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See detailSeasonal variability of carbon dioxide and methane in the rivers and lagoons of Ivory Coast (West Africa)
Koné, Y. J. M.; Abril, G.; Delille, Bruno ULg et al

Poster (2009)

Detailed reference viewed: 10 (3 ULg)
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See detailTransinusoidal portal vein embolisation with Onyx: feasibility study in pigs
Smits; Hav; Vanlengenhoeve et al

Poster (2009)

Detailed reference viewed: 37 (1 ULg)
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See detailCarbon cycling in the mixolimnion of Lake Kivu (East Africa)
Borges, Alberto ULg; Descy, J.-P.; Delille, Bruno ULg et al

Poster (2009)

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See detailSynthèse et propriétés tensioactives de nouveaux surfactants provenant de matières premières renouvelables.
Laurent, Pascal ULg; Razafindralambo, Hary ULg; Wathelet, Bernard ULg et al

Poster (2009)

A l'heure actuelle, le bioraffinage se présente de plus en plus comme une alternative prometteuse aux filières pétrochimiques puisqu'il vise à la fois le remplacement d'une partie du pétrole comme source ... [more ▼]

A l'heure actuelle, le bioraffinage se présente de plus en plus comme une alternative prometteuse aux filières pétrochimiques puisqu'il vise à la fois le remplacement d'une partie du pétrole comme source d'énergie et le développement de produits chimiques issus de la biomasse (végétale principalement) tels que détergents, produits phytopharmaceutiques, dissolvants, matières plastiques, etc. La valorisation de carbohydrates provenant de matières premières renouvelables fait ainsi actuellement l'objet de nombreuses recherches. Dans ce cadre, la synthèse de nouveaux tensioactifs non ioniques dérivés des acides Dglucuronique et D-galacturonique a été effectuée. [less ▲]

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See detailNon destructive testing by digital shearography using a Savart plate
Michel, Fabrice ULg; Blain, Pascal ULg; Renotte, Yvon ULg et al

Poster (2009)

Shearography is a growing optical technique in the field of non-destructive testing (NDT). Hololab developed an out of plane, in line and almost common path interferometer based on polarization states ... [more ▼]

Shearography is a growing optical technique in the field of non-destructive testing (NDT). Hololab developed an out of plane, in line and almost common path interferometer based on polarization states separation using a coated prism for digital phase-shifting shearography. This setup is efficient but does not allow varying the shearing direction, that is an important parameter for defects detection and quantification. To overcome this disadvantage, the coated prism is substituted by a Savart plate device that allows scanning several shearing directions by rotating the device around the light propagation axis. Many advantages of the prism substitution are discussed. The behaviour of the Savart plate as a shearing device is experimentally analyzed to optimize its integration within the interferometer. Recorded phasemaps in NDT for different shearing directions are presented. [less ▲]

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See detailEvaluation of the antitumor activity of 16K prolactin
Kinet, Virginie; Nguyen, Ngoc-Quynh-Nhu ULg; Sabatel, Céline et al

Poster (2009)

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See detailReptile cell cultures for nucleolar studies
Lamaye, Françoise; Thiry, Marc ULg

Poster (2009)

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See detailReintroduction & effects on their environment of indigenous plants of the Cerrado
Buisson, Elise; Le Stradic, Soizig ULg; Negreiros, Daniel et al

Poster (2009)

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See detailThe use of Macronet resins to recover γ-decalactone produced by Rhodotorula aurantiaca from the culture broth
Alchihab, Mohamed ULg; Destain, Jacqueline ULg; Aguedo, Mario ULg et al

Poster (2009)

The objective of this study was to recover the γ-decalactone produced by R. aurantiaca from the culture broth using three Macronet resins (MN-100, MN-102 and MN-202).

Detailed reference viewed: 27 (4 ULg)
See detailDevelopment of a financial model for Geriatric Day Hospitals
Gillain, Daniel ULg; Fecher-Bourgeois, Fabienne ULg; Velghe, A. et al

Poster (2009)

Detailed reference viewed: 31 (19 ULg)
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See detailDéveloppement des filières Jatropha décentralisées au Sénégal
Terren, Marieke ULg; Saverys, S.; Jacquet de Haverskercke, P et al

Poster (2009)

Detailed reference viewed: 48 (11 ULg)
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See detailThe post-harvest quality of bananas is determined by pre-harvest factors
de Lapeyre de Bellaire, Luc; Chillet, Marc; Lassois, Ludivine ULg et al

Poster (2009)

Detailed reference viewed: 28 (12 ULg)
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See detailHolocene environmental changes in lake sediments from Northern Chilean Patagonia (45-48°S)
Nuttin, L.; Fagel, Nathalie ULg; Bertrand, S. et al

Poster (2009)

Detailed reference viewed: 9 (2 ULg)
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See detail3D anatomy of Heinrich Layer 2.
Van Rooij, D.; Zaazi, N.; Fagel, Nathalie ULg et al

Poster (2009)

Detailed reference viewed: 7 (1 ULg)
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See detailENVIRONMENTAL ASPECTS OF CLAY EXPLOITATION FOR FIRED CLAY BRICKS IN CAMEROON
Njoya, A.; Bastin, D.; Melo, U. et al

Poster (2009)

Detailed reference viewed: 71 (14 ULg)
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See detailNutritional markers course after oral supplementation with different forms of iodine in Holstein non-lactating cows
Guyot, Hugues ULg; VanParijs, Sandrine; Uyttenhoef, Aude et al

Poster (2009)

Iodine (I) deficiency is commonly reported in cattle around the world and is often associated with clinical or sub-clinical diseases. As most of clinical signs are not pathognomonic, diagnosis has to be ... [more ▼]

Iodine (I) deficiency is commonly reported in cattle around the world and is often associated with clinical or sub-clinical diseases. As most of clinical signs are not pathognomonic, diagnosis has to be confirmed by biochemical analyses such as plasmatic inorganic iodine (PII) or urinary I. Different oral mineral forms of I are available in Europe for cattle. The aim of the study was to compare the kinetic of I in blood and urine in non-lactating cows, following oral administration of different forms of I. Five groups of 6 non-lactating cows (aged 6 ± 2 years, weight 604 ± 89 kg), receiving the same ration (11 kg dry matter) and housed in the same conditions (tied-stall and straw) underwent a double-blinded trial during 2 months. Excepting in Group A (Control), all cows received a daily oral supplementation of I equal to 5 ppm, in the form of Ca(IO3)2 (Group B), KI (Group C), organic form of I 1 (Group D) and organic form of I 2 (Group E). Formulas of the organic forms of I are not public and coverable by patent. Supplementation was stopped at T45. Blood and urine samples were taken at T0, T15, T30 and T60. Thyroxine (T4) was measured at T0, T30 and T60 while PII and urinary I were measured at the 4 times of the trial. Student-t test and multiple comparisons of means (mix crossed model) were used to compare I and T4 concentrations between groups and times. All characteristics about the cows and I levels in blood or urine were not significantly different at T0 (p>0.1). There was no significant difference (p>0.1) between groups B, C, D, E at the different times of the trial. PII and urinary I in Group A were significantly lower than in other groups (p<0.01) at T15 and T30. Highest concentrations of I (PII up to 242 ± 30 µg/L and urinary I up to 2326 ± 439 µg/L) were reached at T15 for groups B, D and E. At T60, PII (19 ± 4 µg/L) and urinary I (110 ± 29 µg/L) of all groups reached the basal level. A good correlation was found between PII and urinary I (r² = 0.77). No significant differences were found about T4 (67 ± 10 nmol/L) in all groups and times (p>0.1). PII and urinary I are good markers to assess I nutritional status. No difference was found between either inorganic or organic forms of I, nor between them. Concerning the mineral forms of I, Ca(IO3)2 might be preferably used because of its higher stability in the mineral complexes. [less ▲]

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See detailContribution to the study of semiochemical slow release formulations. Development of flash chromatographic methods.
Heuskin, Stéphanie ULg; Farmakidis, Julien; Lorge, Stéphanie et al

Poster (2009)

Detailed reference viewed: 21 (7 ULg)
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See detailCHARACTERIZATION AND OPTIMIZATION OF PEPTIDE ENCAPSULATION IN PEGYLATED LIPOSOMES
Ducat, Emilie ULg; Brion, Michael; Evrard, Brigitte ULg et al

Poster (2009)

Purpose: Print 3G is a peptidic antagonist of oncoprotein involved in breast cancer, containing 25 amino acids. The purpose of this work is to study the peptide encapsulation into PEGylated liposomes. Two ... [more ▼]

Purpose: Print 3G is a peptidic antagonist of oncoprotein involved in breast cancer, containing 25 amino acids. The purpose of this work is to study the peptide encapsulation into PEGylated liposomes. Two formulations composed of SPC:CHOL:mPEG-750-DSPE (47:47:6) or SPC:CHOL:mPEG-2000-DSPE (47:47:6) were investigated. Methods: Unilamellar vesicles containing either mPEG750 or mPEG2000 were prepared by hydration of lipid films method. Unfortunately, a loss of Print 3G was observed during the different steps of this manufacturing technique giving rise to encapsulation efficiencies close to 0 %. Thus, the freeze-thawing method was used to enhance the amount of Print 3G encapsulated into blank liposomes prepared using the above procedure. Because many factors may influence the peptide entrapment into the vesicles (number of freeze-thawing cycles, lipid concentration, peptide concentration, mixing time and liposome composition), a design of experiment was performed (for the screening, a Plackett and Burman plan; for the optimization, a central composite design). Results: The encapsulation efficiencies obtained by the freeze-thawing method in standard conditions, varied between 17.26 ± 0.46 % (n=3) for liposomes containing mPEG750 and 26.20 ± 7.98 % (n=3) for those comprising mPEG2000. Among the different considered factors, the screening permitted to identify two factors having a positive and significant influence on the encapsulation efficiencies: the number of freeze-thawing cycles and the lipid concentration, while the presence of mPEG2000 or mPEG750 had a relatively weak effect on the encapsulation. Concerning the peptide concentration and the mixing time, no influence was revealed. For the second part of the DOE, the positive factors were optimized for the liposomes containing mPEG2000. The obtained results for liposomes containing mPEG2000 revealed a theoretical optimum at 64.75 ± 3.55 % when 11 freeze-thawing cycles were applied and for the following lipid concentrations: 36.1 mM SPC, 36.1 mM CHOL and 4mM mPEG-2000-DSPE. The experimental results showed an encapsulation efficiency of 62.68 ± 2.93 %. Conclusion: Changing the manufacturing technique permitted a significant encapsulation of Print 3G into liposomes. The DOE led to a significant improvement of encapsulation efficiencies for the liposomes containing mPEG2000. Thereafter, an optimization design for liposomes containing mPEG750 will be started. Acknowledgements: This work was supported by the Ministry of the Walloon Region. [less ▲]

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See detailCHARACTERIZATION AND OPTIMIZATION OF PEPTIDE ENCAPSULATION IN PEGYLATED LIPOSOMES
Ducat, Emilie ULg; Brion, Michael; Evrard, Brigitte ULg et al

Poster (2009)

Purpose: The purpose of this work is to study the peptide encapsulation into PEGylated liposomes. Two formulations (SPC:CHOL:mPEG-750-DSPE (47:47:6) or SPC:CHOL:mPEG-2000-DSPE (47:47:6)) were investigated ... [more ▼]

Purpose: The purpose of this work is to study the peptide encapsulation into PEGylated liposomes. Two formulations (SPC:CHOL:mPEG-750-DSPE (47:47:6) or SPC:CHOL:mPEG-2000-DSPE (47:47:6)) were investigated. Methods: Blank SUV liposomes were prepared by the lipid film hydration and the encapsulation was achieved by applying freeze-thawing cycles. Because many factors may influence peptide entrapment (number of freeze-thawing cycles (NC), lipid concentration (LC), peptide concentration (PC), mixing time (MT) and liposome composition (COMP)), a design of experiment (DOE) was performed. Results: The screening permitted to identify two factors having a positive and significant influence on the encapsulation efficiencies (NC and LC) while the liposome composition had a relatively weak effect. For the second part of the DOE, the positive factors were optimized for liposomes containing mPEG2000. The obtained results revealed a theoretical optimum at 64.75±3.55% when 11 cycles were applied and for the following LC: 36.1mM SPC, 36.1mM CHOL and 4mM mPEG-2000-DSPE. Experimental results showed an encapsulation efficiency of 62.68±2.93%. Conclusion: The DOE led to significant improvement of encapsulation for liposomes containing mPEG2000. Thereafter, an optimization design for liposomes containing mPEG750 will be started. Acknowledgements: This work was supported by the Ministry of the Walloon Region. [less ▲]

Detailed reference viewed: 26 (5 ULg)
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See detailPercutaneous penetration studies of ibuprofenencapsulated into nanoparticles using different skin membrane models
Destrée, Caroline; Wouters, Johan; Deleu, Magali ULg et al

Poster (2009)

Detailed reference viewed: 7 (1 ULg)
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See detailHolocene environmental changes in lake sediments from Northern Chilean Patagonia
Nuttin; Fagel, Nathalie ULg; Brogniet et al

Poster (2009)

Detailed reference viewed: 33 (0 ULg)
See detailevaluation of two protein extractions protocols for pichia anomala proteome analysis
Bajji, M.; Delaplace, Pierre ULg; Mauro, S. et al

Poster (2009)

Detailed reference viewed: 29 (6 ULg)
Peer Reviewed
See detailCoupled hydro-thermo-mechanical analysis of a deep radioactive waste disposal based on porous media mechanics
Passarotto, Mareva; Luison, Loris; Sanavia, Lorenzo et al

Poster (2009)

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See detailPurification de protéines associées à la gestation (PAG) chez le porc
Dethier, M.; Melo de Sousa, Noelita ULg; Balci, S. et al

Poster (2009)

Detailed reference viewed: 19 (2 ULg)
See detailInvolvement of autophagic pathway in the hypoxia-induced resistance to etoposide in HepG2
Cosse, Jean-Philippe ULg; Sermeus, Audrey; Flamant, Lionel et al

Poster (2009)

Detailed reference viewed: 8 (1 ULg)
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See detailDepth resolution and surface transients in crystalline Silicon at ultra low energies
Goossens, Jozefien; Berghmans, Bart; Franquet, Alexis et al

Poster (2009)

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See detailFunctional amphiphilic and degradable copolymers for drug delivery systems
Freichels, Hélène ULg; Pourcelle, Vincent; Plapied, Laurence et al

Poster (2008, December 18)

Detailed reference viewed: 28 (4 ULg)
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See detailBiohydrogen production from anaerobic digestion of carbohydrate organic matter.
Hiligsmann, Serge ULg; Masset, Julien ULg; Beckers, Laurent ULg et al

Poster (2008, December 16)

Hydrogen has received wide attention in the last decade as a clean energy vector. The major advantage of energy from hydrogen is the zero carbon emissions, since the utilization of hydrogen, either via ... [more ▼]

Hydrogen has received wide attention in the last decade as a clean energy vector. The major advantage of energy from hydrogen is the zero carbon emissions, since the utilization of hydrogen, either via combustion or via fuel cells, results in pure water. At industrial scale, steam reformation of methane is currently the major hydrogen producing process. However recently, increasing interest has been paid on biological production of hydrogen gas. Indeed, biohydrogen generation from renewable biomass would reduce dependence on fossil fuel, decrease the carbon dioxide emissions and produce usable bioenergy. Biological production of hydrogen using anaerobic bacteria is an exciting and promising new area of technology development that offers the potential production of usable hydrogen from a variety of renewable resources such as carbohydrates from agriculture or agro-food industries. This biological system is called dark fermentation and the most interesting bacteria strains are Clostridium sp. The investigations carried out at CWBI involve selection and characterization of bacteria strains, optimization of the biotechnological process and design of highly efficient bioreactors. [less ▲]

Detailed reference viewed: 63 (8 ULg)
See detailLes mobilisations pour la cause des femmes en RDCongo
Grenade, Sophie ULg

Poster (2008, December 12)

Detailed reference viewed: 21 (9 ULg)
See detailCharacteristics of Saturn's polar atmosphere and auroral electrons derived from HST/STIS, FUSE and Cassini/UVIS spectra
Gustin, Jacques ULg; Pryor, W.; Feldman, P. et al

Poster (2008, December 01)

Ultraviolet spectra of Saturn's aurora obtained with the Hubble Space Telescope Imaging Spectrograph (STIS), the Cassini Ultraviolet Imaging Spectrograph (UVIS) and the Far Ultraviolet Spectroscopic ... [more ▼]

Ultraviolet spectra of Saturn's aurora obtained with the Hubble Space Telescope Imaging Spectrograph (STIS), the Cassini Ultraviolet Imaging Spectrograph (UVIS) and the Far Ultraviolet Spectroscopic Explorer (FUSE) have been compared to synthetic spectra of electron-excited H2 in order to derive various auroral characteristics, such as the energy of the primary precipitating electrons and the H2 temperature at the altitude of the aurora. Two physical processes have been exploited: the absorption by hydrocarbons in the FUV and H2 self-absorption in the EUV. We find energies in the range 10-18 keV, which locates Saturns's aurora between 0.1 and 0.3 μ bar. We also determined that the auroral H2 emission is characterized by a temperature of ~400K, consistent with temperatures measured in the infrared, but much higher than what is expected from equatorial atmospheric models. These new results bring valuable constraints on both polar atmospheric models and theoretical studies of the ionosphere-magnetosphere coupling. [less ▲]

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See detailOverlay Routing using Coordinate Systems
Cantin, François ULg; Gueye, Cheikh Ahmadou Bamba ULg; Kaafar, Mohamed Ali ULg et al

Poster (2008, December)

We address the problem of finding indirect overlay paths that reduce the latency between pairs of nodes in an overlay. To this end we propose to rely on an Internet Coordinate System (ICS), namely Vivaldi ... [more ▼]

We address the problem of finding indirect overlay paths that reduce the latency between pairs of nodes in an overlay. To this end we propose to rely on an Internet Coordinate System (ICS), namely Vivaldi, to estimate RTTs and help find these interesting detours. We define two initial criteria to illustrate our approach and assess their true/false positive rates. [less ▲]

Detailed reference viewed: 105 (48 ULg)
See detailSignes de conflit d’intentions dans un syndrome de déconnexion calleuse : cas J.B.
VINCENT, Eric ULg; DELRUE, Gaël ULg; SALMON, Eric ULg et al

Poster (2008, December)

Presentation of a patient showing multiple symptoms of a callosal disconnection.

Detailed reference viewed: 9 (2 ULg)
See detailCarbon Cycle and Climate Sensitivity in an Earth System Model
Mouchet, Anne ULg; Loutre, M.; Fichefet, T. et al

Poster (2008, December)

The sensitivity of the potential feedbacks between climate and biogeochemical cycles (BGC) is adressed with the help of LOVECLIM, a global three-dimensional Earth system model of intermediate complexity ... [more ▼]

The sensitivity of the potential feedbacks between climate and biogeochemical cycles (BGC) is adressed with the help of LOVECLIM, a global three-dimensional Earth system model of intermediate complexity. Key physical or biogeochemical parameters of LOVECLIM are varied within their range of uncertainty in order to provide an ensemble of parameter sets resulting in contrasted climate and global carbon cycle sensitivities. The selected climate parameter sets lead to a climate sensitivity ranging from 2 to 4°C and a reduction of the Atlantic meridional overturning circulation (MOC) ranging from 20 to 60% after 1 kyr in response to identical external forcings. The key parameters for the carbon cycle were chosen among those with the largest impact on the marine biogeochemical cycle and on the response of atmospheric CO2 to emission scenario. We then analyze the results of freshwater hosing experiments in which both the climate parameters and the BGC parameters are modified. These experiments allow to examine the impact of changes in climate sensitivity and of MOC reduction over the biogeochemical cycles as well as to assess the potential feedback from the carbon cycle onto the climate. A decreasing MOC directly impacts the ocean biogeochemistry. Most of the model setups show a decline in export production although some parameter sets yield reorganisation of the large scale ocean circulation, which leads to different behaviour of the ocean biogeochemistry. The atmospheric carbon is also affected by a decrease of the MOC. While most parameter sets cause a modest increase in atmospheric CO2, consecutive to the decrease of the continental vegetation, some model versions exhibit an amplification of the atmospheric CO2 response to the forcing. The mechanisms leading to the different responses for the different parameter sets are examined and discussed. [less ▲]

Detailed reference viewed: 41 (0 ULg)
See detailPreparation and characterization of thermoresponsive iron nanoparticles for biomedical applications
Sibret, Pierre ULg; Aqil, Abdelhafid ULg; Gohy, Jean-François et al

Poster (2008, November 28)

Detailed reference viewed: 24 (4 ULg)
See detailElectrografting of thermo-responsive polymer films on conducting surfaces
Gabriel, Sabine; Stach, M.; Confortini, O. et al

Poster (2008, November 28)

Detailed reference viewed: 27 (2 ULg)
See detailPolymer membrane by electrospinning
Aqil, Abdelhafid ULg; Grignard, Bruno ULg; Croisier, Florence ULg et al

Poster (2008, November 28)

Detailed reference viewed: 41 (9 ULg)
See detailNew strategies to prepare melt processable polymer-grafted gold nanoparticles
Alexandre, Michaël ULg; Abetz, Volker; Boschetti-de-Fierro, A. et al

Poster (2008, November 28)

Detailed reference viewed: 31 (6 ULg)
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See detailLe Childhood Anxiety Sensitivity Index-Revised (CASI-R) : Etude de validation.
Stassart, Céline ULg; Depauw, Brigitte; Delvaux, Muriel ULg et al

Poster (2008, November 28)

La sensibilité à l'anxiété est la peur des sensations corporelles liées à l’anxiété, qui proviendrait de croyances que ces sensations ont des conséquences somatiques, psychologiques ou sociales néfastes ... [more ▼]

La sensibilité à l'anxiété est la peur des sensations corporelles liées à l’anxiété, qui proviendrait de croyances que ces sensations ont des conséquences somatiques, psychologiques ou sociales néfastes. Ce concept a été très peu exploré dans le contexte infantile. L’AS étant considérée comme un facteur de risque dans le développement et le maintien des troubles anxieux, ceci montre l’intérêt de s’intéresser davantage à l’outil d’évaluation de l’AS dans le contexte infantile, le Childhood Anxiety Sensitivity Index revised. L'objectif de cette étude est de d'évaluer les propriétés psychométriques de la version française de la CASI-R auprès d'un échantillon de 60 enfants âgés de 10 à 11 ans. En ce qui concerne les résultats, la confrontation de la CASI-R aux qualités psychométriques nous fournit des premiers éléments en faveur de l’intérêt clinique et de la pertinence théorique de cet outil dans le contexte infantile. En ce sens, la poursuite de son développement paraît constituer une perspective intéressante. [less ▲]

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See detailModelling the Ionosphere over Europe: Investigation of NeQuick Formulation
Bidaine, Benoît ULg; Warnant, René ULg

Poster (2008, November 18)

The modelling of the Total Electron Content (TEC) plays an important role in global satellite navigation systems (GNSS) accuracy, especially for single-frequency receivers, the most common ones ... [more ▼]

The modelling of the Total Electron Content (TEC) plays an important role in global satellite navigation systems (GNSS) accuracy, especially for single-frequency receivers, the most common ones constituting the mass market. For the latter and in the framework of Galileo, the NeQuick model has been chosen for correcting the ionospheric error contribution. It has been designed to calculate the electron density at a given point of the ionosphere according to the time conditions and the solar activity. This electron density can be integrated along the path from the receiver to the considered satellite to provide the TEC. For Galileo, a parameter Az (“effective ionisation level”) will be provided to the model as solar activity information and will be daily updated by the ground stations. Since NeQuick was chosen for Galileo purpose, a new version of the model has been released. It involves simplifications in the representation of the bottomside as well as a unique formula for a key parameter of the topside formulation previously defined through two equations, each one used for six months of the year. Hence we decided to investigate consecutive improvements and remaining weaknesses of this new formulation. To this extent, we take benefit of various ionosphere data from several European stations (Chilton in UK, Dourbes in Belgium, El Arenosillo and Roquetes in Spain, Pruhonice in Czech Republic) where ionosonde and GPS TEC data are available for different solar activity levels. These data allow us to study NeQuick representation of the ionosphere at mid-latitudes. We investigate the difference between GPS-derived vTEC and corresponding values from NeQuick for the latest years (between solar maximum in 2000 and minimum in 2007) in order to observe the temporal dependencies towards Universal Time, season and solar activity. We use ionosonde data to constrain the model so that we can concentrate on its formulation of the profile only. We especially highlight the improvements from the second version of NeQuick and show the critical importance of the topside formulation. [less ▲]

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See detailIonospheric variability which degrades the precision of real time GNSS applications
Wautelet, Gilles ULg; Lejeune, Sandrine; Warnant, René ULg

Poster (2008, November 18)

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See detailDirect block of SK2 and SK3 current by the sigma agonist 1,3-di-(2-tolyl)guanidine
Lamy, Cédric; Moreau, Jacqueline ULg; Dilly, Sébastien ULg et al

Poster (2008, November 17)

Sigma receptors are widely distributed in the central nervous system where they modulate neurotransmitter release, receptor function, ionic channel activity and calcium homeostasis. Two subtypes of sigma ... [more ▼]

Sigma receptors are widely distributed in the central nervous system where they modulate neurotransmitter release, receptor function, ionic channel activity and calcium homeostasis. Two subtypes of sigma receptors have been identified (sigma-1 and sigma-2) with different pharmacological profiles, anatomical distribution and physiological functions. 1,3-Di-(2-tolyl)guanidine (DTG) is a sigma-1 and sigma-2 agonist which is widely used to probe the function of these receptors. It has recently been shown that sigma-1 receptor activation reduces the opening of SK channels in the hippocampus. We have observed that DTG (100 µM) reduces the apamin-sensitive afterhyperpolarization (AHP) of dopaminergic neurons within a slice preparation by ~60%, an effect not observed with other sigma agonists. In addition, neither the selective sigma-1 antagonist BD 1047 (30 µM) nor haloperidol (1 µM) blocked the effect of DTG, which suggested that the inhibition of the AHP might result from a direct block of the underlying SK channels. Whole-cell recordings were made from HEK293 cells transiently transfected with rSK2 or hSK3 cDNA in symmetrical K+ conditions with currents activated by a [Cai] of 1 µM. Expressed SK2 and SK3 channels displayed a classical pharmacology, being blocked by apamin with mean IC50’s of 100 pM and 4 nM, respectively. In contrast, both channel subtypes were blocked with equal sensitivity by N-methyl-laudanosine (NML). DTG inhibited both SK2 and SK3 currents with the same potency (IC50’s were ~30 µM). A mutation that rendered both SK2 and SK3 insensitive to apamin and NML produced a current that was still sensitive to DTG. This direct block of SK channels may be important to consider in relation to the pharmacological effects of this compound. [less ▲]

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See detailModelling soil heterotrophic respiration in an agricultural soil: Model structure and first comparison with experimental data.
Buysse, Pauline ULg; Le Dantec, Valérie; Sagnier, Charlotte et al

Poster (2008, November 17)

Ce travail visait à adapter un modèle de respiration hétérotrophe du sol à un site agricole situé en Hesbaye (Belgique) et cultivé avec une rotation betterave sucrière / blé d’hiver / pomme de terre / blé ... [more ▼]

Ce travail visait à adapter un modèle de respiration hétérotrophe du sol à un site agricole situé en Hesbaye (Belgique) et cultivé avec une rotation betterave sucrière / blé d’hiver / pomme de terre / blé d’hiver. A long terme, ce modèle fera partie intégrante d’un modèle plus important qui décrira la respiration totale du sol et l’évolution du contenu en carbone du sol dans les cultures. Le modèle utilisé dans ce travail est dérivé du modèle Century, possède un pas de temps journalier et couvre une échelle spatiale de l’ordre de l’écosystème. La paramétrisation du modèle a été réalisée sur base d’une recherche bibliographique et de données collectées sur le site Carbo-Europe de Lonzée. Les caractéristiques du sol sont issues d’analyses réalisées sur des sols limoneux, typiques de la région de Hesbaye. Les variables conductrices (variables météorologiques et apports de litière) furent obtenues suite à une campagne de mesures de 4 ans réalisée sur le site expérimental de Lonzée. Les paramètres biochimiques du blé, de la pomme de terre et de la betterave furent tirés de la littérature. Une analyse de sensibilité fut réalisée en vue de classer les différents paramètres par rapport à leur impact sur le taux de respiration et les contenus en carbone de chaque pool. Les paramètres les plus importants étaient ceux contrôlant la réponse à la température, l’apport de litière et les teneurs en lignine et en azote. Des différences d’impact à court et long terme ont aussi été mises en évidence, notamment à cause de la dynamique de stabilisation des pools et des types de résidus de culture. Finalement, cette analyse nous a permis de définir de futures expériences qui seraient nécessaires pour améliorer l’ajustement du modèle sur des données expérimentales. [less ▲]

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See detailPESTEAUX : A project for building GIS-based tool for the assessment of water pollution risks at local scale due to pesticides
Bah, Boubacar Billo ULg; Noël, Stéphanie; Buffet, Dominique et al

Poster (2008, November)

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See detailThe amazing bouncing droplet
Terwagne, Denis ULg; Dorbolo, Stéphane ULg; Vandewalle, Nicolas ULg et al

Poster (2008, November)

When a low viscosity oil droplet is laid onto the surface of a high viscosity oil liquid, it stays at rest for a moment before coalescence. The coalescence can be delayed and sometimes inhibited by ... [more ▼]

When a low viscosity oil droplet is laid onto the surface of a high viscosity oil liquid, it stays at rest for a moment before coalescence. The coalescence can be delayed and sometimes inhibited by injecting fresh air under the droplet. This can happen when the surface of the bath oscillates vertically. In this case the droplet basically bounces on the interface [1, 2]. We observe that the conditions for bouncing depends on the frequency, more precisely we observe resonance when the eigenfrequency of the droplet is excited. Lord Rayleigh expressed the droplet deformation modes in terms of spherical harmonics Y m. We present different l experimental mode of deformation with the corresponding spherical harmonic model. In some conditions, a droplet presents a non axi-symmetric mode of deformation. That leads to a rotation of the droplet and to a horizontal displacement. [less ▲]

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See detailSpatiotemporal Distribution of Polysaccharides During the Mammalian Auditory Organ Development
Thelen, Nicolas ULg; Compère, Philippe; Malgrange, Brigitte et al

Poster (2008, October 31)

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See detailPersistent organic pollutants in wild seabass (Dicentrarchus labrax) from the Northeast atlantic coastal regions and relationship with thyroid hormone levels
Schnitzler, Joseph ULg; Thomé, Jean-Pierre ULg; Das, Krishna ULg

Poster (2008, October 30)

Polychlorinated biphenyls (PCBs) and organochlorine pesticides like Dichloro-Diphenyl-Trichloroethane (DDTs), Hexachlorocyclohexanes (HCHs), Aldrin and Dieldrin were analysed in the muscle of sea bass ... [more ▼]

Polychlorinated biphenyls (PCBs) and organochlorine pesticides like Dichloro-Diphenyl-Trichloroethane (DDTs), Hexachlorocyclohexanes (HCHs), Aldrin and Dieldrin were analysed in the muscle of sea bass (Dicentrarchus labrax) sampled in coastal regions near several important European river mouths (Garonne, Charente, Loire, Seine and Scheldt). These organochlorinated compounds are known to influence the endocrine system of many fish species and mammals and are thus qualified as endocrine disrupters. To highlight a potentially harmful effect of these compounds on the thyroid function of these fishes, we measured the muscular concentrations of thyroid hormones T3 and T4 by Radio-Immuno-Assay. The contamination levels were as follows: the highest concentrations were measured in individuals collected from the coastal region near the Scheldt > Seine > Loire > Charente and the lowest levels were observed in sea bass from coastal regions near the Garonne (from 2422 to 6188 ng.g-1 lw). The measured levels were generally higher than those reported in literature in sea bass from other regions in the Mediterranean Sea. Contamination patterns were different depending on the sampling area and thus the river input of pollutants. The multivariate statistical analysis revealed a significant relationship between the measured persistent organic pollutants and thyroid hormones in muscle. We cannot exclude the assumption that an endocrine disruption of the thyroid related to these pollutants could be the origin of these modifications of the thyroid hormone concentrations. [less ▲]

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