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See detailTemporal evolution and extreme value analysis of precipitations in Burkina Faso
Bel, Liliane; Weiss, Jérôme; Boreux, Jean-Jacques ULg et al

Poster (2011, March 23)

Modeling of damaging extreme events is of great interest for the risk managers who want to implement some protections. It is based on the so-called generalized extreme values model. In the environmental ... [more ▼]

Modeling of damaging extreme events is of great interest for the risk managers who want to implement some protections. It is based on the so-called generalized extreme values model. In the environmental sciences, we need to model the extremes of two or more processes like the daily rainfall recorded in various points of a given region. Each individual process could be modeled using univariate technique, but this strategy could not take into account for dependence of extreme values. For instance, consider two sites A and B fairly close to one another. If we observe an extreme value of the daily rainfall at site A, this information impacts the probability to observe an extreme value at site B even if we never recorded such value at B. The basic modeling tool is formed by so-called max-stable processes which take into account the possible spatial dependence through so-called extremal coefficient. We illustrate with annual maximum daily rainfall values recorded in 41 stations in Burkina Faso. [less ▲]

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See detailAdvanced Data Interpolating Variational Analysis. Application to climatological data.
Troupin, Charles ULg; Sirjacobs, Damien ULg; Rixen, Michel et al

Poster (2011, March 21)

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See detailReversal of acepromazine-induced hemodynamic alterations by norepinephrine in standing horses
pequito, Manuel; Amory, Hélène ULg; Peters, Fabrice et al

Poster (2011, March 18)

Acepromazine (ACP) is a phenothiazine commonly used to sedate horses. Additionally, ACP exerts strong anti-inflammatory effects, which might have a therapeutic potential in horses suffering from systemic ... [more ▼]

Acepromazine (ACP) is a phenothiazine commonly used to sedate horses. Additionally, ACP exerts strong anti-inflammatory effects, which might have a therapeutic potential in horses suffering from systemic inflammatory response syndrome (SIRS). However, the ACP-induced vasodilation precludes its use in horses with SIRS-related cardiovascular compromise. The objective of this study was to test if the hemodynamic effects of the administration of 0,1 mg/kg of ACP could be counteracted by an intravenous infusion of norepinephrine (NOR) at 1ug/kg/min in healthy horses. In 5 healthy adult horses, a 15 minutes NOR IV infusion was administered 45 minutes after an injection of 0,1 mg/kg of ACP IV. The systolic arterial blood pressure (SAP) was non-invasively measured by Doppler sphingometry at the tail. Hemodynamics of the median artery of the left forelimb were studied using Doppler ultrasonography, through calculation of the vessel’s surface (SURF), diameter (DIAM), circumference (CIRC), and peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (MV), volumetric flow (VF) and resistivity index (RI) of the flow. Both SAP and Doppler parameters were determined at regular intervals during the entire study. ACP induced a hypotension and a vasodilatation, that were evidenced by a significant rise of the SURF, DIAM, CIRC, PSV, EDV, MV and VF and reduction of the SAP and RI. During NOR infusion, all these ACP-induced hemodynamic changes were reversed. These findings suggest that a continuous IV NOR infusion at 1ug/kg/min is able to revert ACP-induced hypotension and vasodilation in healthy adult horses. [less ▲]

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See detailTwo-Dimensional, M-Mode and Pulsed Wave Doppler Echocardiographic Reference Values in Healthy Adult Saanen Goats
Leroux, Aurélia ULg; Moonen, Marie ULg; Farnir, Frédéric ULg et al

Poster (2011, March 18)

Echocardiography has become a routine non invasive cardiac diagnostic tool in most species. Accurate measurement of cardiac dimensions requires reference values, which are poorly documented in goats ... [more ▼]

Echocardiography has become a routine non invasive cardiac diagnostic tool in most species. Accurate measurement of cardiac dimensions requires reference values, which are poorly documented in goats. Goats are animals easy to handle with a body and heart size comparable to humans’. This makes goats an attractive candidate for the development of animal models for human cardiology research. The aim of this study was to test the repeatability and to establish the reference values of bi-dimensional (2D-), time-motion (M-) mode and pulsed wave (PW) Doppler echocardiographic variables in adult goats. Six healthy female adult Saanen goats were investigated three times by the same observer at one day interval using a standardized 2D-, M-mode and PW Doppler echocardiographic protocol. Calculation of the coefficient of variation for each variable measured within day and depending on the day allowed to evaluate their degree of variability. A single echocardiographic examination was performed in 6 other goats by the same observer, and the obtained values were added to these obtained on the third day of the 6 first goats. Then the observed mean, the standard deviation and the range of these measurements were calculated to establish the reference values of echocardiographic parameters in unsedated adult healthy female Saanen goats. Statistical analysis revealed a good inter-day repeatability of the 2D- and M-mode echocardiographic cardiac measurements, but PW Doppler parameters presented moderate to high variability, as documented in other species. Echocardiographic reference values obtained in healthy adult Saanen goats were similar to those reported in healthy adult sheep and in healthy adult humans. [less ▲]

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See detailUse of environmental isotopes to infer flow in the highly exploited aquifer system of the Diass region (Senegal)
Madioune, Diakher Hélène; Faye, Serigne; Dassargues, Alain ULg et al

Poster (2011, March 14)

The Diass horst multilayered aquifer constitutes a complex hydrogeological system. But stable isotopes are illustrated to be powerful tools for clarifying the origin of recharge water, and the groundwater ... [more ▼]

The Diass horst multilayered aquifer constitutes a complex hydrogeological system. But stable isotopes are illustrated to be powerful tools for clarifying the origin of recharge water, and the groundwater dynamics due to high exploitation of the system. Used with 3H and 14C, data confirms that most of the investigated groundwater are palaeowaters. Pumping has an impact on groundwater flow evidenced by the different water isotope compositions that illustrates the transient conditions of the system. Mixing of old waters and recently recharged (tritiated) waters occurs in some exploited boreholes, indicates lateral flow to the pumping field through the main groundwater flow directions. [less ▲]

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See detailDERP6 and C3orf75 regulate the invasive potential of melanoma cells as subunits of the elongator complex
Close, Pierre ULg; Gillard, magali; Ladang, A et al

Poster (2011, March 12)

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See detailOccurrence of aphid predators in Belgian agro-ecosystems
Vandereycken, Axel ULg; Durieux, Delphine ULg; Joie, Emilie ULg et al

Poster (2011, March 06)

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See detailMicroorganisms from aphids attract hoverflies and enhance their efficacy
Leroy, Pascal ULg; Sabri, Ahmed ULg; Heuskin, Stéphanie ULg et al

Poster (2011, March 05)

Aphids are some of the most serious pests of crops worldwide, causing major yield and economic losses. They damage plants by feeding on the phloem sap, excreting copious amounts of honeydew and, in some ... [more ▼]

Aphids are some of the most serious pests of crops worldwide, causing major yield and economic losses. They damage plants by feeding on the phloem sap, excreting copious amounts of honeydew and, in some cases, vectoring plant diseases. Here, we report the first isolation of a bacterium from the pea aphid Acyrthosiphon pisum honeydew, Staphylococcus sciuri, which is involved in the release of semiochemicals acting as a kairomone for aphid natural enemies. These semiochemicals were identified by Solid-Phase Microextraction (SPME) and Gas Chromatography-Mass Spectrometry (GC-MS). Our results show that this bacterium plays a key role in the interactions between aphids and natural enemies because it is the direct source of volatiles used by the aphidophagous hoverfly Episyrphus balteatus (De Geer) (Diptera: Syrphidae) to locate its aphid prey. Through wind-tunnel experiments, some specific semiochemicals produced by S. sciuri were identified as significant attractants and ovipositional stimulants. Also, assays under greenhouses and in potato fields have demonstrated that a culture medium containing the bacterium S. sciuri strongly attracts and induces the oviposition of hoverflies, enhancing their efficiency as biological control agents. The use of this no pathogenic bacterium could provide a very novel approach towards enhancing the efficacy of biological control agents to control aphids in field crops and greenhouse systems. [less ▲]

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See detailCo-Occurence of two rare autosomal recessive syndromes in a young patient
SEGERS, Karin ULg; Debray, François-Guillaume ULg; Wuyts, W et al

Poster (2011, March 04)

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See detailAn efficient biphasic synthesis of polymer-grafted reduced graphite oxide based nanocomposites
Vuluga, Daniela ULg; Thomassin, Jean-Michel ULg; Molenberg, Isabel et al

Poster (2011, March 03)

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See detailIn vitro culture of the parasitic wasp Aphidius ervi: Sweet dream or Reality
Sabri, Ahmed ULg; Leroy, Pascal ULg; Haubruge, Eric ULg et al

Poster (2011, March 03)

Aphidius ervi is an entomophagous parasitoid and represents an effective parasitoid of several aphid species that cause great damages in agriculture. Several investigations, for its in vitro mass ... [more ▼]

Aphidius ervi is an entomophagous parasitoid and represents an effective parasitoid of several aphid species that cause great damages in agriculture. Several investigations, for its in vitro mass production, have achieved a limited success and suggest that in vitro culture of this valuable biological control agent is rather closer to a dream than reality. Our work provides a chronological study of A. ervi development, from the oviposition until hatching of the first instar larva, in the body of the pea aphid Acyrthosiphon pisum. We show that this parasitoid has some characteristics in its embryological development that are rather complex and different from most other reported insects, which can be phylogenetically very close. Some of these characteristics concern extraembryonic membranes and could be among the causes of the limited success achieved in the in vitro culture. [less ▲]

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See detailWEEE management using LCA methodology : the fridge case study
Belboom, Sandra ULg; Renzoni, Roberto ULg; Deleu, Xavier et al

Poster (2011, March 01)

This study is based on WEEE life cycle assessment and more particularly on treatment and valorization of fridges and freezers. Two scenarios were envisaged: situation before fridge collect and the Belgian ... [more ▼]

This study is based on WEEE life cycle assessment and more particularly on treatment and valorization of fridges and freezers. Two scenarios were envisaged: situation before fridge collect and the Belgian current situation where all national fridges are treated in Liège. Results of this study prove the importance of collecting and valorizing fridges especially for old fridges containing refrigerant banned by the Montreal Protocol. Recovery and incineration of the pollutants permit to reduce climate change and ozone depletion impacts. [less ▲]

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See detailMir-146a : A new angiostatic miRNA with tumor-suppressive properties
Halkein, Julie ULg; Castermans, Karolien; Malvaux, Ludovic et al

Poster (2011, March)

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See detailRSZ22, a dynamic nucleocytoplasmic shuttling SR splicing factor
Tillemans, Vinciane ULg; Rausin, Glwadys; Stankovic, Nancy ULg et al

Poster (2011, March)

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See detailNon-visual brain sensitivity to light in aging
Daneault, V; Vandewalle, Gilles ULg; Hébert, M et al

Poster (2011, March)

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See detailLe système non-visuel chez l'être humain : lumière, oeil et cerveau
Daneault, V; Vandewalle, Gilles ULg; Dumont, M et al

Poster (2011, March)

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See detailElement fluxes, forest floor characteristics and microbial activities under deciduous tree species after conversion of a Norway spruce (Picea abies (L.) Karst.) stand
Bazgir, Masoud ULg; Guillaume, Patricia ULg; Carnol, Monique ULg

Poster (2011, March)

Forest management is currently confronted with major questions, such as how to adapt plantation forests to a changing world. This questioning is not only essential with regard to forest health and ... [more ▼]

Forest management is currently confronted with major questions, such as how to adapt plantation forests to a changing world. This questioning is not only essential with regard to forest health and productivity, but also within the frame of climate mitigation. As Norway spruce monocultures (Picea abies) have been planted in Europe beyond their assumed natural range, are subjected to forest decline and have negative impacts on ecological conditions, conversion into mixed stands has been suggested. Tree species can influence nutrient inputs, soil microbial activity, soil chemistry and nutrient cycling in forest ecosystems. These tree species effects on biogeochemical cycles may vary according to soil type, site characteristics and land use history. The objective of the present study was to quantify element fluxes in throughfall and seepage water, forest floor exchangeable element pools and nitrogen transformations, 12 years after conversion from Picea abies monocultures to a mixed forest stand. Measurements were performed under young and mature Picea abies, Alnus glutinosa (L.) Gaertn., Quercus robur L. and Sorbus aucuparia L. Thus trees have grown on the same site, sharing identical initial soil conditions and site history, so that potential effects on microbial processes and soil properties can be imputed to tree species. Results showed that conversion had a short term impact on nutrient budgets and nutrient cycling in the upper soil layer; in particular on input fluxes of acidifying cations, soil base saturation, net N mineralization and nitrification. [less ▲]

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See detailEnhanced insulin sensitivity variability in the first 3 days of ICU stay: Implications for TGC
Chase, Geoffrey; Le Compte, Aaron; Penning, Sophie ULg et al

Poster (2011, March)

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See detailHow to use existing power lines to evacuate twice as much wind power ?
Nguyen, Huu-Minh ULg; lambin, jean-jacques; Lilien, Jean-Louis ULg

Poster (2011, March)

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See detailPerformance of three HIV-1 DNA real-time PCRs for early diagnosis in infants and adults
Iserentant, G.; Masquelier, C.; Lambert, C. et al

Poster (2011, March)

Background Early pediatric HIV-1 diagnosis is a challenge in resource limited countries to identify HIV-infected newborns to provide early ART treatment. HIV DNA PCR testing is an accurate method for ... [more ▼]

Background Early pediatric HIV-1 diagnosis is a challenge in resource limited countries to identify HIV-infected newborns to provide early ART treatment. HIV DNA PCR testing is an accurate method for diagnosis in newborns and could be valuable for monitoring HIV infection in adults. We have evaluated the analytical, clinical performances and genotype inclusivity of 3 real-time Taqman PCRs targeting the ltr, int and env genes. Material and methods Total DNA was extracted from whole blood and Dried Blood Spots (DBS) using the NucleoSpin Blood kit (Macherey Nagel) and the Chelex resin. DNA amplification was performed using the Qiagen Multiplex PCR kit and detected on a 7300 Real time PCR system (Applied Biosystems). Method validation was realized as required by ISO 15189 standard. The accuracy profile methodology was applied. HIV-1 DNA of ACH2 cells (0, 25, 50, 100, 1000 and 5000 copies/PCR) mixed in whole blood were measured in 4 different series (2 PCR kits and 2 operators) of 5 independent DNA extraction of each standard. Linear and quadratic weighted and non weighted regression models were tested. Trueness, precision, limit of quantifications of the method and accuracy of the results were obtained for each model and compared. 93 whole blood samples of ART treated-patients with undetectable or low viraemia of 16 B and 77 non-B subtypes were assessed. Clinical evaluation of the assay was performed on 26 whole blood samples and 238 DBS from infants of Guinea Conakry determined HIV+ using the rapid Bioline HIV test Results The calibration model providing the most accurate results was the linear regression with an r² equal to 0.92 for ltr, 0.88 for int and 0.95 for env. Trueness, precision and accuracy were highly acceptable for the 3 sets of primers/probe not exceeding -0.23 log(copies/PCR) for bias and 0.5 log(copies) for intermediate precision standard deviation, respectively. The estimated lower limit of quantification was 41, 475 and 25 copies/PCR for ltr, int and env respectively. The accuracy profile of each gene showed that each future measurement using this assay has 80% probability to be within a limit of 0.5 log (copies/PCR) around the reference or true value of copies of each gene. 52/93 whole blood samples of ART-treated patients had 3 positive genes (Ct<40 cycles), 38/93 had two positive genes and 4/93 had only one positive gene (ltr). Among these patients, 3 were assigned as long term progressors and one was a subtype C strain. Clinical evaluation of the assay identified 1 HIV-1 infected newborn and 3 adults (at least 2 positive genes) for which HIV-1 infection was confirmed either by serology or viral load techniques as well as 96 HIV-1 infected infants using DBS. Conclusions This assay is suitable for detection of proviral HIV-1 DNA in infants and adults on whole blood and DBS samples. Despite an estimated lower limit of quantification higher than ltr and env, the int PCR was required to achieve a good genotype inclusivity. The method was fully validated as required by ISO 15189 and showed to provide sufficiently reliable results. [less ▲]

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See detailImmune thrombocytopenic purpura - Watchful waiting pharmacologic treatment?
Guffens, Anne; Bequet, Emeline ULg; Defontaine, Elizabeth et al

Poster (2011, March)

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See detailMBD5 deletion: a new recurrent cause of mental retardation
JACQUINET, Adeline ULg; STEVENS, René; DEMONCEAU, Nathalie et al

Poster (2011, March)

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See detailMiR-146a an angiostatic miRNA elevated in peripartum cardiomyopathy
Halkein, Julie ULg; Castermans, Karolien; Malvaux, Ludovic et al

Poster (2011, March)

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See detailValidation of a Virtual Patient and Virtual Trials Method for Accurate Prediction of TGC Protocol Performance
Suhaimi, Fatanah; Le Compte, Aaron; Penning, Sophie ULg et al

Poster (2011, March)

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See detailTemporal evolution of biogeochemical properties of landfast sea ice at Barrow (Alaska)
Zhou, Jiayun ULg; Tison, Jean-Louis; Eicken, Hajo et al

Poster (2011, March)

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See detailAging and effect of blue monchromatic light on non-visual functions
Daneault, V; Vandewalle, Gilles ULg; Teikari, P et al

Poster (2011, March)

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See detailConservation et valorisation de la Bleue Mixte au travers du projet franco-belge BlueSel
Colinet, Frédéric ULg; Glorieux, Géry; Beguin, Emmanuel et al

Poster (2011, March)

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See detailType II GM1 gangliosidosis presenting as isolated psychomotor regression
JACQUINET, Adeline ULg; STEVENS, René; DEMONCEAU, Nathalie et al

Poster (2011, March)

Detailed reference viewed: 17 (2 ULg)
See detailThe impact of diet in shaping microbiota revealed by a comparative study in children from Europe and Rural Africa
De Filippo, C.; Massart, Sébastien ULg; Di Paola, M. et al

Poster (2011, March)

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See detailOrganisms as ecosystems engineers: the case of amphipod grazers from Posidonia oceanica meadows
Michel, Loïc ULg; Schnitzler, Joseph ULg; Dupont, Alessandra et al

Poster (2011, February 25)

Posidonia oceanica is a seagrass endemic to the Mediterranean Sea, and is able to form large monospecific areas, called meadows. These meadows shelter high biomasses and biodiversities of amphipod ... [more ▼]

Posidonia oceanica is a seagrass endemic to the Mediterranean Sea, and is able to form large monospecific areas, called meadows. These meadows shelter high biomasses and biodiversities of amphipod crustaceans. Moreover, It is now established that several species of these amphipods feed on the macro-epiphytes present on the leaves of the seagrass. Here, we performed in situ experiments to assess whether this grazing activity could impact the dynamics of the leaves’ epiphytic cover, and thus influence the functioning of the meadow as an ecosystem. We used microcosms containing monospecific populations of 3 amphipods taxa (Apherusa chiereghinii, Dexamine spiniventris and Gammarus spp.), and placed them directly in the meadow, at a depth of 10m. Biomasses of erected macroalgae and erected animals (hydrozoans, bryozoans) were lower in all grazed treatments. However, none of the studied taxa seemed to consume encrusting epiphytes, either vegetal or animal. This selective grazing pressure by amphipods may release encrusting epiphytes from competition for space, light and/or nutriments with the fast-growing erected algae, and could thus play an important role in the structuring of the epiphytic cover from P. oceanica leaves. Moreover, this top-down control might keep erected algae biomass to a normal, sustainable level, therefore also benefiting the seagrass itself. Our results also indicate that amphipod trophic activity caused nitrogen enrichment in both grazed (erected algae) and non-grazed (encrusting algae & seagrass leaves) vegetal tissues. A plausible interpretation could be that sloppy feeding and excretion by the grazers enhanced availability of this nutrient, which is typically limiting for photosynthesis in shallow P. oceanica meadows. This emphasizes the fact that grazing is not a simple negative interaction, but that it can also benefit the primary producers. Our results thus indicate that amphipods from P. oceanica meadows seem to be bound to the epiphytic cover of the leaves by complex and multilateral trophic interactions, and have an indirect influence on the seagrass itself. Amphipods may therefore play an important part in the functioning of the epiphyte/seagrass/grazer system of these meadows, and thus act as ecosystems engineers. This abstract is dedicated to the freshly born Adèle and Côme. [less ▲]

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See detailLe stress du cavalier et du cheval en compétition
Peeters, Marie ULg; Closson, Coline ULg; Beckers, Jean-François ULg et al

Poster (2011, February 24)

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See detailDimebon Enhances Hippocampus-Dependent Learning in Mouse Models of Appetitive Y-Maze and Inhibitory Step-Down Memory Tasks in Mice
Vignisse, Julie ULg; Steinbusch, Harry W.M.; Bolkunov, Alexei et al

Poster (2011, February 23)

Dimebon, a compound recently proposed for a treatment of Alzheimer’s disorder, was suggested to have memory enhancing properties in pre-clinical and clinical studies. We investigated whether dimebon at ... [more ▼]

Dimebon, a compound recently proposed for a treatment of Alzheimer’s disorder, was suggested to have memory enhancing properties in pre-clinical and clinical studies. We investigated whether dimebon at doses acutely (0.1 mg/kg and 0.5 mg/kg) or repeatedly (0.1 mg/kg) administered to mice via i.p. injections, increases memory scores respectively in an appetitive and an inhibitory learning task. Acute treatment with dimebon at the dose 0.1 mg/kg did not affect learning scores in 3-month-old C57BL/6N. Acute treatment with higher dose of dimebon (0.5mg/kg) was found to enhance inhibitory learning in 3-month-old mice as shown in the step-down avoidance paradigm in C57BL/6N mice. In a model of appetitive learning, a spatial version of the Y-maze, repeated treatment with dimebon increased the rate of correct choices and decreased the latency of accessing a water reward after water deprivation. Repeated administration of dimebon also increased the duration of drinking behaviour during training/testing procedures although water consumption behaviour was not altered. Additional behavioural tests were carried out to investigate possible non-specific effects of dimebon on parameters of drinking, anxiety and exploration/locomotion. Our data suggest that dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory tasks in mice. [less ▲]

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See detailANALYSING THE SOIL STRUCTURE UNDER DIFFERENT TILLAGE SYSTEMS USING X-RAY MICROTOMOGRAPHY AND PF CURVES
Beekkerk van Ruth, Jöran ULg; Degre, Aurore ULg; Aubinet, Marc ULg et al

Poster (2011, February 23)

Assessing soil structure is primordial when comparing tillage systems. Whilst most conventional techniques characterize global parameters, X-ray microtomography allows a characterization of the poral ... [more ▼]

Assessing soil structure is primordial when comparing tillage systems. Whilst most conventional techniques characterize global parameters, X-ray microtomography allows a characterization of the poral space at a µm-scale. These results, combined with data from pF curves, can form a solid basis in order to quantify soil physical fertility. Soil samples were taken from the organic topsoil on two Belgian experimental sites implementing both conventional tillage (CT, ploughing) and simplified tillage (ST, superficial works), without straw restitution: Gentinnes, Brabant Wallon (March 2010), and Gembloux, Namur (November 2010). On the Gentinnes site (Aba(b)1), CT and ST have been implemented since October 2005, with a beet/winter wheat rotation. On the Gembloux site (Aba(b)), CT and ST have been implemented since September 2008, with a winter wheat cultivation since end 2009. Tomography (10 samples for Gentinnes, 8 for Gembloux) and pF curves (10 samples for Gentinnes, 14 for Gembloux) were used for analysis. Pressure pans were used in order to obtain the pF curves on 100 cm³ undisturbed samples. Soil cores (3 cm diameter, 5 cm height) were scanned using a Skyscan-1172 µ-CT device. The conical beam, operating at 100 kV, produced images having a 17µm pixel size, using a 16-bit 1048×2000 pixels camera equipped with an aluminium filter. The raw images were then treated under Matlab® for binarization, using a thresholding loop to fit the measured and the calculated porosity of each sample (Beckers et al, 2011). The 2D binary images were then analyzed under Matlab® and Skyscan™ CT-analyzer. On the site of Gentinnes, pF analysis showed a greater available water content (between pF 4.2 and 2.5) for ST, and a greater efficient porosity (between saturation and pF 2.5) for CT. The differences in available water content, although not significant, were confirmed by site observation. Tomography analysis yielded the following: under ST, the pores are smaller and the anisotropy less developed. As for the poral connectivity, it was found greater in CT. On the site of Gembloux, however, no significant differences were found between the tillage systems concerning the pF curves. Tomography analysis showed smaller pores for simplified tillage, but the differences deduced by the tomographic analysis of the Gentinnes samples concerning connectivity and anisotropy were not found in this case. To conclude, from the results, the soil structure is found to differ between CT and ST. The pores tend to be smaller and less oriented in ST, whilst in CT pores are more connected. Soils undergoing a CT show a greater efficient porosity, whilst soils under ST display a greater available water content. However, these differences were mostly spotted on the Gentinnes site: in Gembloux, the differences between the samples were less marked. This could be due to the fact that the soil did not have time to differentiate yet (less than 3 years of tillage differentiation). More sampling is needed in any case before inferring general conclusions from these observations. A further analysis of the soil images, especially concerning pore orientation, will be done in order to fully exploit the tomography results. [less ▲]

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See detailHistone deacetylase 5 is a regulator of S phase progression
Peixoto, Paul ULg; Pirotte, Sophie ULg; Matheus, Nicolas ULg et al

Poster (2011, February 05)

Detailed reference viewed: 17 (5 ULg)
See detailFading of modern Prussian blue pigments in linseed oil medium
Samain, Louise ULg; Silversmit, Geert; Sanyova, Jana et al

Poster (2011, February 04)

Detailed reference viewed: 22 (6 ULg)
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See detailMiR-146a an angiostatic miRNA elevated in peripartum cardiomyopathy
Halkein, Julie ULg; Castermans, Karolien; Malvaux, Ludovic et al

Poster (2011, February)

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See detailALT "4"CER "Alternatives for cereals"
Delcour, Alice ULg; Van Stappen, Florence ULg

Poster (2011, February)

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See detailA collection of polar cyanobacteria to contribute to the inventory of the biodiversity and discover the biotechnological potential
Wilmotte, Annick ULg; Waleron, Kzryzstof; Waleron, Malgorzata et al

Poster (2011, February)

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See detailmicroRNA-21 Exhibits Anti-Angiogenic Function by Targeting RhoB Expression in Endothelial Cells
Sabatel, Céline; Malvaux, Ludovic; Bovy, Nicolas ULg et al

Poster (2011, February)

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See detailDoppler Echocardiographic follow up of three horses with congestive heart failure and treated with quinapril, digoxin, and diuretics
Leroux, Aurélia ULg; Sandersen, Charlotte ULg; Borde, Laura ULg et al

Poster (2011, February)

Angiotensin converting enzyme inhibitors are recommended therapy in human and canine patients with congestive heart failure (CHF), but little is known concerning their efficiency to treat horses with CHF ... [more ▼]

Angiotensin converting enzyme inhibitors are recommended therapy in human and canine patients with congestive heart failure (CHF), but little is known concerning their efficiency to treat horses with CHF. Enalapril has been shown to be poorly absorbed in horses and quinapril has been shown to decrease the severity of the insufficiency and to increase the stroke volume (SV) and the cardiac output (CO) in horses with mitral regurgitation (MR) without signs of CHF. The objective of this cases report was to evaluate the effect of quinapril associated with routine treatment in horses with CHF. Three horses with clinical, echocardiographic and electrocardiographic signs of severe MR, CHF and secondary atrial fibrillation were studied (Fig 1 to 3). None of them had been previously treated for those problems. According to the ACVIM classification system for management of canine CHF, they were therefore classified in class C. They were treated with quinapril 0.2mg/kg SID PO, digoxin 0.011mg/kg BID PO, and furosemide 1mg/kg BID IM. Standard echocardiographic and Doppler measurements were performed before treatment (T0), and 1 and 4 weeks after starting treatment (W1 and W4, respectively). All horses showed a transient clinical improvement (decrease of edemas and disappearance of the dyspnea) after 1 week of treatment, but clinical signs deteriorated within the following weeks in 2 horses that were euthanized for ethical reasons. The third horse kept a steady clinical status and was discharged with the treatment pursued at home. Evolution (in %) of main echocardiographic parameters at W1 and W4 compared to T0 values are showed in Table1. Large individual variations in response to the treatment were seen. Nevertheless, in all horses, a decrease of the Heart Rate (HR) was observed after 1 week of treatment, but the HR increased again after 1 month of treatment (Fig 4). On the contrary, no increase in SV or CO, and no decrease in LVIDd were seen in response to treatment (Fig 5). In the 2 horses that were euthanized, the fractional shortening (FS) and the pre-ejection to ejection time ratio (PEP/ET) decreased and the mitral E peak velocity increased with treatment, whereas they followed the opposite evolution in the surviving horse. No conclusion can be drawn from this study because of the limited number of studied cases. However, it would be interesting to extend it to additional cases and to less severely affected cases (i.e. horses classified in class C after initial treatment or class B horses). Negative chronotropic effect of digoxin was suggested after 1 week of treatment since a decrease of the HR was observed in all horses. However, this effect seemed to decrease after 1 month of treatment. Those preliminary results of echocardiography suggest that quinapril in association with digoxin and furosemide at the used dosage could be inefficient to reduce the left ventricular filling pressure and to improve the myocardial contractility in horses with severe CHF. This could however be due to the fact that the 3 studied horses were cases refractory to classic treatment (thus to be classified in class D). [less ▲]

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See detailMiR-146a: an angiostatic miRNA with tumor-suppressive properties
Halkein, Julie ULg; Bovy, Nicolas ULg; Castermans, Karolien et al

Poster (2011, February)

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See detailDriven weak to strong pinning crossover in a partially nanopatterned superconductor
Shaw, Gorky ULg; Sinha, Jaivardhan; Mohan, Shyam et al

Poster (2011, February)

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See detailL'adolescience, un univers de contradictions
Vanesse, Marc ULg; Colmant, François ULg; Colson, Justine ULg et al

Poster (2011, February)

Un documentaire produit par le Lemme (Laboratoire d'étude sur les médias et la médiation) et réalisé dans cinq écoles au cours duquel des adolescents parlent librement de leurs rapports avec les sciences.

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See detailEffect of kynurenic acid on sensitivity to cortical spreading depression in rats
Chauvel, Virginie ULg; Vamos, Eniko; Pardutz, Arpat et al

Poster (2011, January 31)

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See detailNucleolar structure across evolution : the transition between bi- and tricompartmentalized nucleoli lies within the class Reptilia
Franck, Claire; Lamaye, Françoise; Thelen, Nicolas ULg et al

Poster (2011, January 31)

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See detailSpatio-temporal localisation of β-actin and γ-actin isoforms during the development of the organ of Corti in rat from the embryonic day 18 (E18) to the post-natal day 25 (P25).
Johnen, Nicolas ULg; Thelen, Nicolas ULg; Cloes, Marie ULg et al

Poster (2011, January 31)

The auditory organ, the organ of Corti (OC), is a highly specialized structure composed by specific cellular types. The sensory cells (HC) are characterized by stereocilia at their apex and are necessary ... [more ▼]

The auditory organ, the organ of Corti (OC), is a highly specialized structure composed by specific cellular types. The sensory cells (HC) are characterized by stereocilia at their apex and are necessary for the sound perception. Theses cells are supported by supporting cells. Based on their morphology and physiology, at least four types of supporting cells can be identified in the OC: inner and outer pillar cells (PC), phalangeal cell and Deiter’s cells. Sensory and supporting cells have cytoskeletons containing β-actin and γ-actin isoforms. In the adult mammalian cochlea, amounts of γ-actin increase and β-actin decrease in the order: outer pillar cells, inner pillar cells, Deiters’ cells and hair cells. In sensory cells, γ-actin appears to be the most prominent component with an apparent γ-actin/β-actin ratio of approximately 2:1 (Hofer et al., 1997). β-actin is present in the cuticular plate but is more concentrated in the stereocilia, especially at the base where the stereocilia insert into the cuticular plate. The amount of γ-actin differs less between these structures, the stereocilia and cuticular plate, although its expression is apparently higher towards the tip of stereocilia and it is the predominant isoform of the hair cell's lateral wall (Furness et al., 2005). The differential subcellular localization of two actin isoforms suggests they may play different functions in auditory organ. In the brain, β-actin is restricted to dynamic structures whereas γ-actin is more ubiquitously distributed and occurs in relatively quiescent regions (Micheva et al., 1998). In the present study, by using confocal microscopy, we investigated the spatio-temporal localisation of β-actin and γ-actin isoforms during the development of the OC in rat from the embryonic day 18 (E18) to the post-natal day 25 (P25). Our results indicated that the labelling for both actin isoforms changed during the OC development. Between E18 and P25, we observed a labelling for β-actin in the apical region of the HC. Between P8 and P25, the feet of PC are also β-actin-positive. Unlike β-actin, between E18 and P10, γ-actin is detected in the basal region of supporting cells. Between P12 and P25, the labelling for γ-actin is preferentially localized in the apical surface of the HC. Our results revealed that during development β-actin isoform preceded γ-actin isoform in the apical region of HC. They also suggest that γ-actin isoform might be involved in attachment of supporting cells with their basal membrane and that β-actin isoform might play a role in PC reorganization during the formation of Corti tunnel. [less ▲]

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See detailNovel HDAC/DNMT Twin inhibitors interfere with angiogenesis
Shiva Shankar, Thammadihalli Veerasangaiah ULg; Sulka, Béatrice ULg; Blacher, Silvia ULg et al

Poster (2011, January 31)

DNA methylation and histone deacetylation are two key epigenetic modifications that play central role in regulation of gene expression. Several studies have shown that histone deacetylases (HDAC) and DNA ... [more ▼]

DNA methylation and histone deacetylation are two key epigenetic modifications that play central role in regulation of gene expression. Several studies have shown that histone deacetylases (HDAC) and DNA methyltransferases (DNMT) inhibitors are potent anti-angiogenic compounds. Though combination of HDAC and DNMT inhibitors are now being examined in clinical trials of hematological malignancies, little work has been done to understand the effect of this combination on physiological and tumoral angiogenesis. We have designed and tested a family of twin drugs with intrinsic HDAC and DNMT inhibitory activities in relevant models of angiogenesis in vitro (Human Umbilical Vein Endothelial Cells – HUVEC and aortic ring) and in vivo (chick chorioallantoic membrane and Zebrafish). We have identified a lead compound having quantifiable anti-angiogenic effect without cytotoxicity affecting global histone acetylation and DNA methylation levels. In order to elucidate its anti-angiogenic mechanism, we characterized gene expression pattern simultaneously with the methylation profile of HUVEC cells treated with the lead compound and reference epigenetic modulators. This approach based on parallel microarray analyses permitted us to underscore a list of genes exclusively affected by the lead compound but not by other HDAC or DNMT inhibitors. These genes were then analyzed using the Ingenuity Pathway software revealing potential involvement of a subset of genes in angiogenesis. Our present aim is to validate the expression levels of a series of genes with respect to epigenetic mechanisms (histone modifications and DNA methylation). Finally, the biological relevance of the target genes will be explored by RNA silencing. Hence, we are using these novel epigenetic modulators as a tool to understand the regulatory mechanism of angiogenesis and to develop effective approaches to treat cancer. [less ▲]

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See detailDistribution of glycogen during the development of the organ of Corti
Thelen, Nicolas ULg; Cloes, Marie ULg; Johnen, Nicolas ULg et al

Poster (2011, January 31)

Although the structure of the auditory organ in mature mammals, the organ of Corti, is clearly established, its development is far from being elucidated. Using cytochemical methods at the light and ... [more ▼]

Although the structure of the auditory organ in mature mammals, the organ of Corti, is clearly established, its development is far from being elucidated. Using cytochemical methods at the light and electron microscope levels, we examined the spatiotemporal distribution of polysaccharides during the development of the organ of Corti in rats from embryonic day 16 (E16) to postnatal day 15 (P15). At E16, small polysaccharide inclusions were detected in the cytoplasm of the future inner pillar cells by electron microscope only. These inclusions became obvious at the light microscope level at E17. At E19, the polysaccharide deposits were important within the inner pillar cells and they arose in the Hensen cells cytoplasm. Polysaccharide accumulations also appeared in the outer pillar cells and the Deiters cells from P3-P4. As the organ of Corti developed, the amount of polysaccharide inclusions within the inner and outer pillar cells decreased. At P15, large amount of polysaccharide deposits were visible in the Deiters cells whereas they had almost disappeared from the inner and outer pillar cells. Finally, we showed that the polysaccharide deposits present in the developing organ of Corti are PAS-positive and can be digested with a salivary amylase, suggesting that they are essentially constituted of glycogen. [less ▲]

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See detailDimebon enhances hippocampus-dependent learning in both appetitive and inhibitory memory tasks in mice
Vignisse, Julie ULg; Steinbusch, Harry W.M.; Bolkunov, Alexei et al

Poster (2011, January 31)

Dimebon, a compound recently proposed for a treatment of Alzheimer’s disorder was suggested to have memory enhancing properties in pre-clinical and clinical studies. We investigated whether dimebon at ... [more ▼]

Dimebon, a compound recently proposed for a treatment of Alzheimer’s disorder was suggested to have memory enhancing properties in pre-clinical and clinical studies. We investigated whether dimebon at doses acutely (0.1 mg/kg and 0.5 mg/kg) or repeatedly (0.1 mg/kg) administered to mice via i.p. injections, increases memory scores respectively in an appetitive and an inhibitory learning task. Acute treatment with dimebon at the dose 0.1 mg/kg did not affect learning scores in either 3-month-old C57BL/6N or CD1 mice. Acute treatment with higher dose of dimebon (0.5mg/kg) was found to enhance inhibitory learning in 3- and 7-month-old mice as shown in the step-down avoidance paradigm in C57BL/6N mice. No effects on learning were seen in CD1 mice. In a model of appetitive learning, a spatial version of the Y-maze, repeated treatment with dimebon increased the rate of correct choices and decreased the latency of accessing a water reward after water deprivation. Repeated administration of dimebon also increased the duration of drinking behaviour during training/testing procedures although behaviours in others tests or water consumption were not altered. Acute treatment of water-deprived and non-water-deprived mice with dimebon also did not affect their water intake. Our data suggest that dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory tasks in mice. [less ▲]

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See detailSpatio-temporal localization of the glial fibrillary acidic protein (GFAP) in the spiral ganglion from the 16th embryonic day until the 25th postnatal day in rats
Cloes, Marie ULg; Thelen, Nicolas ULg; Johnen, Nicolas ULg et al

Poster (2011, January 31)

The spiral ganglion (SG) is responsible for the conduction of the information between the sensory epithelium of the auditory organ (the organ of Corti) and the central nervous system. The origin and ... [more ▼]

The spiral ganglion (SG) is responsible for the conduction of the information between the sensory epithelium of the auditory organ (the organ of Corti) and the central nervous system. The origin and nature of the SG glial cells in mammals are barely known, although glial cells are essential to the development and the working of the nervous system. Using confocal microscopy, we studied the spatio-temporal distribution of the GFAP in the rat SG from the 16th embryonic day (E16) until the 25th postnatal day (P25). We performed a double-labelling experiment targeting GFAP- and betaIIItubulin-positive cells. BetaIII-tubulin is used for the labelling of (pro)neural cells, according to a previous preliminary study from our team. Our first results show clearly that the GFAP is expressed in the SG from P0 until P25. A homogenous labelling is found in the cytoplasm of a few dispersed unidentified cells among the (pro)neurons, whereas a granular labelling appears among a group of cells neighbouring the bundle of fibers innervating the organ of Corti. The identity of the GFAP-positive cells will be further investigated by electron microscopy. The reason why the labelling of the GFAP adopts those two different aspects is still unknown. Moreover, it seems that, surprisingly, some cells of the ganglion are not labelled by either marker. The possibility that such cells correspond to fibroblasts will be tested thanks to the labelling of vimentin. [less ▲]

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See detailidentification of new parterns of the NOD2 protein
Lecat, Aurore ULg; Di Valentin, Emmanuel ULg; Fillet, Marianne ULg et al

Poster (2011, January 27)

Detailed reference viewed: 27 (13 ULg)
See detailRole of MDC1 in NF-kappaB activation by DNA double-strand breaks.
Sabatel, Hélène; Piette, Jacques ULg; Habraken, Yvette ULg

Poster (2011, January 25)

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See detailRespiratory pathologies in foals
Frizot, Myriam; Amory, Hélène ULg; Borde, Laura ULg et al

Poster (2011, January 22)

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See detailTHE USE OF VAC® THERAPY IN HORSES
Lazzaretti, Sarah; Grulke, Sigrid ULg; Serteyn, Didier ULg et al

Poster (2011, January 22)

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See detailMettalic foreign body in a horse: case report
Evrard, Laurence ULg; Bolen, Géraldine ULg; Gougnard, Alexandra ULg et al

Poster (2011, January 22)

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See detailContribution of CT scan for lesions affecting the spine
Deudon, Pauline ULg; Peeters, Dominique ULg; Balligand, Marc ULg et al

Poster (2011, January 22)

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See detailIdiopathic central diabetes insipidus and severe hypernatremia in a cat
Desmas, Isabelle ULg; Manens, Jefferson ULg; Rizza, Maïlis et al

Poster (2011, January 22)

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See detailSémiologie des troubles de l'attention : attention convergente et attention divergente, continuum développemental de la petite enfance à l'âge adulte.
SCHOLL, Jean-Marc ULg; PHILIPPE, Paule ULg

Poster (2011, January)

Introduction : Le « Trouble de l'attention avec ou sans hyperactivité » (ADHD ou TDA/H) connu chez l'enfant, demeure une clinique peu identifiée à l'âge adulte alors qu'elle persiste dans 50 % des cas ... [more ▼]

Introduction : Le « Trouble de l'attention avec ou sans hyperactivité » (ADHD ou TDA/H) connu chez l'enfant, demeure une clinique peu identifiée à l'âge adulte alors qu'elle persiste dans 50 % des cas (Faraone et al., 2006) ; plus précisément, l'étude de l'évolution comparative des symptômes entre 6 ans et 20 ans révèle que l'hyperactivité diminue de 50 %, l'impulsivité de 40 % et l'inattention ne diminue que de 20 % (Mick et al., 2004). La sémiologie des troubles de l'attention est particulièrement méconnue chez l'adulte, or, elle peut interférer avec le pronostic socio-affectif de la personne (Bange, dans Revol & Brun, 2010). Dans le DSM IV-TR le trouble de l'attention isolé nécessite la présence de 6 des 9 critères d'inattention mentionnés. La littérature évoque aussi une distinction sémiologique en formes « d'attention convergente » et « d'attention divergente » ; ce vocable médical est plus global que celui de la neuropsychologie mais possède un substrat neurophysiologique qu'un traitement spécifique de l'E.E.G. permet de mesurer sur l'ensemble du cortex cérébral par les degrés respectifs d'utilisation de processus convergents et divergents lors de tâches en cours (Arns et al., 2009 ; Van den Bergh, 2003 ; van Dongen-Boomsma et al., 2010). Objectif : Affiner la sémiologie des troubles de l'attention tant chez l'enfant que chez l'adulte. Méthode : 1) une revue de la littérature et 2) une étude d'observation qualitative fine avec une « anamnèse sémiologique » détaillée d'un maximum de micro-signes sémiologiques porte sur 14 enfants, âgés de 5 ans 3 mois à 10 ans 7 mois, et 7 adultes de 20 ans à 37 ans présentant un diagnostic de trouble de l'attention (selon le DSM IV). Résultat : Deux tableaux, selon qu'il y a une prépondérance de « l'attention convergente » ou de « l'attention divergente », donnent un descriptif détaillé de la sémiologie. Ces tableaux sont différenciés chez l'enfant et chez l'adulte ; ils permettent d'établir un continuum développemental de la clinique. Réf. : « Bipolarité et ADHD. Recherche sémiologique : continuum développemental de la petite enfance à l'âge adulte et diagnostic différentiel », La psychiatrie de l'enfant, vol. 55/2012, in press. [less ▲]

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See detailPegase : Outil opérationnel de modélisation de la qualité des eaux de surface
Deliège, Jean-François ULg; Everbecq, Etienne ULg; Grard, Aline ULg et al

Poster (2011, January)

Pegase (Planification Et Gestion de l’ASsainissement des Eaux) est un modèle intégré bassins hydrographiques/rivières qui permet de calculer de façon déterministe et prévisionnelle la qualité des eaux des ... [more ▼]

Pegase (Planification Et Gestion de l’ASsainissement des Eaux) est un modèle intégré bassins hydrographiques/rivières qui permet de calculer de façon déterministe et prévisionnelle la qualité des eaux des rivières en fonction des rejets et apports de pollution (relation pression-impact), pour des situations hydrologiques constantes ou non-stationnaires. Pegase est un outil opérationnel doté d’une interface conviviale, s’interfaçant avec des outils propriétaires de type ArcGIS et permettant d’orienter les choix des opérateurs publics et privés en matière de gestion des eaux de surface à l’échelle des bassins versants. [less ▲]

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See detaildoes neoadjuvant radiotherapy promote tumor dissemination ,
Leroi, Natacha ULg; boujouf, Sarah; COUCKE, Philippe ULg et al

Poster (2011, January)

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See detailAquapôle, Cellule Latitudes Sud : Coopération avec les pays du Sud dans le domaine de l’eau
Deliège, Jean-François ULg; Detienne, Xavier; Grard, Aline ULg et al

Poster (2011, January)

L’objectif de la Cellule Latitudes Sud au sein de l'Aquapôle de l'Université de Liège est de favoriser le développement de projets liés à l’eau dans les pays du Sud, et en particulier dans les pays en ... [more ▼]

L’objectif de la Cellule Latitudes Sud au sein de l'Aquapôle de l'Université de Liège est de favoriser le développement de projets liés à l’eau dans les pays du Sud, et en particulier dans les pays en développement. La Cellule Latitudes Sud intervient au niveau de la promotion, la réalisation et/ou la collaboration à différents projets avec une approche pluridisciplinaire et plurisectorielle. Elle s’appuie sur les compétences de l’Aquapôle (ULg) et également sur le réseau de compétences que constituent ses services membres. [less ▲]

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See detailStudy of the combined effect of 5-ALA-based photodynamic therapy and NF-kappaB inhibition on human glioblastoma cell survival
Coupienne, Isabelle ULg; Fettweis, Grégory ULg; Piette, Jacques ULg

Poster (2011, January)

Glioblastoma constitute the most frequent and deadliest type of brain tumors in human adults. They are very resistant to all current therapies and are associated with a huge rate of recurrence. In most ... [more ▼]

Glioblastoma constitute the most frequent and deadliest type of brain tumors in human adults. They are very resistant to all current therapies and are associated with a huge rate of recurrence. In most cases, this type of tumor is characterized by a constitutive activation of the nuclear factor-kappaB (NF-kappaB). This factor is known to be a key regulator of various physiological processes such as inflammation, immune response, cell growth or apoptosis. In the present study, we explored the role of NF-kappaB activation in the sensitivity of human glioblastoma cells to a treatment by 5-aminolevulinic acid (5-ALA)–based photodynamic therapy (PDT). Our results show that inhibition of NF-kappaB improves glioblastoma cell death in response to 5-ALA-PDT. We then studied the molecular mechanisms underlying the cell death induced by PDT combined or not with NF-kappaB inhibition. We found that PDT mainly induced necrosis in glioblastoma cells and NF-kappaB was found to have anti-necrotic functions in this context. In the second part of this study, we examined the role of the kinase RIP3, recently identified as a key effector of the necrotic pathway, in 5-ALA-PDT-induced necrosis and studied whether NF-kappaB interfered in RIP3-dependent necrosis induction. [less ▲]

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See detailLa thérapie institutionnelle est-elle efficace ?
Triffaux, Jean-Marc ULg

Poster (2011, January)

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See detailPyridine Derivatives of Nimesulide as New Promising Anti-inflammatory Agents
Renard, Jean-François ULg; Lecomte, Frédéric ULg; de Leval, Xavier et al

Poster (2011, January)

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See detailCapacité à ressentir la durée du temps : instauration d'une sémiologie développementale en milieu écologique chez des enfants de 2,5 à 12 ans
SCHOLL, Jean-Marc ULg

Poster (2011, January)

Introduction : Comment le clinicien peut-il préciser la sémiologie de « la perception de l'écoulement du temps » chez l'enfant dans son contexte écologique ? En psychologie clinique la perception du temps ... [more ▼]

Introduction : Comment le clinicien peut-il préciser la sémiologie de « la perception de l'écoulement du temps » chez l'enfant dans son contexte écologique ? En psychologie clinique la perception du temps est souvent abordée à partir des repères séquentiels et des capacités rythmiques mais la sémiologie de « la capacité à ressentir la durée du temps » manque de références développementales. Objectif : instaurer « une sémiologie développementale » de « la perception de l'écoulement du temps » chez des enfants typiques, et rechercher des indices sémiologiques de trajectoires développementales atypiques. Hypothèses cliniques : 1) la « capacité à ressentir l'écoulement du temps » a une réalité clinique déterminable par des « indices sémiologiques » au sein de la réalité écologique d'enfants typiques de 2,5 à 12 ans en population générale, 2) une population d'enfants atypiques présente une clinique et un cours développemental différents. Méthodologie : Un « questionnaire d'anamnèse sémiologique » à remplir par les parents a été développé à partir des observations cliniques des chercheurs. 25 questions approchent une « sémiologie écologique » des attitudes de l'enfant pouvant être liées à la perception du temps. Il a été appliqué dans 2 populations d'enfants de 2,5 à 12 ans : 827 enfants typiques en population générale et 297 enfants atypiques consultant des services de suivis psychologiques ambulatoires (S.S.M) (échantillon transnosographique). Des analyses développementales portent sur 4 populations: garçons typiques, filles typiques, garçons atypiques, filles atypiques. Chaque question est considérée comme une variable ordinale à 5 modalités (échelle de Likert). L'analyse (programme Statistica) procède par régression logistique multinomiale de chaque variable en fonction de l'âge et de deux variables explicatives nominales : enfants atypiques et sexe ; les interactions atypique/sexe/âge sont ensuite analysées. Résultats : les questions sont catégorisées selon: 1) La présence d'une évolution développementale (19 variables/25); 2) Une discrimination de la population atypique (12 variables/25 dont 6 variables ont une évolution développementale spécifique aux atypiques), ce qui constitue un questionnaire de dépistage; 3) Une différenciation sexuée (2 variables sur 25). [less ▲]

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See detailPerception de l'écoulement du temps : une sémiologie développementale de 2,5 à 12 ans, population générale versus atypique
SCHOLL, Jean-Marc ULg; PHILIPPE, Paule ULg

Poster (2011, January)

Introduction : En clinique, la perception du temps chez l'enfant est surtout considérée à partir du temps séquentiel mais il y a une quasi-absence de prise en compte de repères sémiologiques de sa ... [more ▼]

Introduction : En clinique, la perception du temps chez l'enfant est surtout considérée à partir du temps séquentiel mais il y a une quasi-absence de prise en compte de repères sémiologiques de sa capacité d'appréhender la durée du temps. Objectif : Développer une sémiologie développementale de « la perception de l'écoulement du temps » en situation écologique. Méthode : Élaboration d'un « questionnaire sémiologique » de la « capacité à ressentir la durée du temps » à remplir par les parents (échelle de Likert) ; recrutement de 2 échantillons d'enfants de 2,5 à 12 ans : 827 enfants typiques en population générale et 297 enfants atypiques consultant des services de suivis psychologiques ambulatoires (S.S.M.) (échantillon transnosographique) ; régression logistique multinomiale de chaque item en fonction de l'âge et de 2 variables explicatives nominales : population atypique et sexe. Résultats : 19 questions/25 ont une évolution développementale ; 2 questions une différence sexuée ; 12 questions/25 différencient la population atypique. Ces 12 questions permettent de relever une sémiologie cliniquement pertinente qui approche la « capacité de ressentir la durée du temps » en milieu écologique ; en voici quelques exemples : - Quand l’enfant est ailleurs (par exemple à l’école ou à la garde d’une personne), il répète souvent la question de savoir quand on viendra le rechercher bien qu’on lui ait déjà souvent répondu ou qu’il en ait déjà souvent fait l’expérience ? - A-t-il toujours besoin de savoir comment va se dérouler sa journée ? - Lorsqu’une activité est prévue, répète-t-il souvent la question de savoir quand elle aura lieu alors qu’on lui a déjà répondu ? - Votre enfant est-il souvent en retard (et pour cela il faut souvent lui rappeler l'heure)? - Quand votre enfant est occupé à une activité, a-t-il tendance à être surpris quand arrive la fin du temps qui était prévu pour celle-ci (comme s’il n’avait pas anticipé que le temps approche de la fin) ? - Spontanément, sans avoir besoin de regarder l’heure, votre enfant « sent-il » qu’une activité en cours approche de l’heure où on va devoir l’arrêter ? (par exemple, spontanément il ressent l’approche de la fin de l’heure de piscine ; il interrompt à temps son jeu pour aller regarder son émission favorite à la TV). [less ▲]

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See detailMiR-146a an angiostatic miRNA elevated in peripartum cardiomyopathy
Halkein, Julie ULg; Castermans, Karolien; Malvaux, Ludovic et al

Poster (2011, January)

Detailed reference viewed: 15 (3 ULg)
See detailThe Cenomanian marine reorganization
Fischer, Valentin ULg

Poster (2011, January)

The middle Cretaceous is usually associated with numerous climatic and oceanic perturbations, and a minor to intermediate extinction event at the Cenomanian-Turonian (CTB) boundary. Amongst marine ... [more ▼]

The middle Cretaceous is usually associated with numerous climatic and oceanic perturbations, and a minor to intermediate extinction event at the Cenomanian-Turonian (CTB) boundary. Amongst marine vertebrate palaeontologists, the CTB is mostly known as the extinction of the last ichthyosaurs (Reptilia), after a long period of decline (e.g. Bardet, 1992; Bardet, 1994; Sander, 2000; Lingham-Soliar, 2003). However, new data from France, Canada and Russia indicates that the diversity of late Early Cretaceous ichthyosaurs was far higher than previously thought, both in terms of taxonomical and ecological diversity, but the Cenomanian ichthyosaur diversity remains extremely low. This suggests that the ichthyosaur extinction is far more severe than initially thought and took place during the whole duration of the Cenomanian, in a diachronic fashion. Additionally, a compilation of the current data on the diversity of other marine vertebrates groups shows that the Cenomanian is a peculiar stage within the Cretaceous, with the radiation burst of marine squamates, such as dolichosaurs and mosasauroids (Bardet et al., 2007; Bardet et al., 2008), as well as chondrichtyans, polycotylid plesiosaurs and teleost fishes (e.g. Cumbaa et al., 2010; Schultze et al., 2010). This profound reorganisation of the marine ecosystems (coeval with the onset of the “Chalk sea”) was probably driven by external, physical factors given the diversity of biotic responses. The numerous potential causes for that major reorganisation renders the identification of its precise mechanisms difficult. [less ▲]

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See detailDiagnostic différentiel ADHD / Bipolarité par une étude de l'évolution développementale de la sémiologie enfants - adultes
SCHOLL, Jean-Marc ULg; PHILIPPE, Paule ULg

Poster (2011, January)

Introduction : La prévalence du Trouble de l'attention avec ou sans hyperactivité (ADHD, TDA/H) est de 3 à 5 % pour les enfants et de 1,9 à 7,3 % pour les adultes dans différentes pays (Kessler et al ... [more ▼]

Introduction : La prévalence du Trouble de l'attention avec ou sans hyperactivité (ADHD, TDA/H) est de 3 à 5 % pour les enfants et de 1,9 à 7,3 % pour les adultes dans différentes pays (Kessler et al., 2006; Fayyad et al., 2007). Le Trouble bipolaire a une prévalence chez l'adulte de 1 % pour le type I et de 4,4 % pour le spectre bipolaire (Merikangas et al., 2007), chez l'adolescent elle est évaluée à 1 % pour le type I et le spectre bipolaire en population juvénile à 6 % (2 à 15) (Benazzi, 2007). Des controverses demeurent quant au recouvrement de ces différentes entités cliniques selon les âges. Gabrielle Carlson a décrit chez l'enfant un tableau bipolaire comportant des symptômes maniaques continus et chroniques avec des symptômes d'ADHD. Ainsi, le « National Institutes of Health (NIH) » a distingué cette forme continue du trouble dans l'enfance, le « severe mood dysregulation », du trouble bipolaire de type I de l'adolescent, le « narrow phenotype » comportant des épisodes thymiques et davantage de symptômes psychotiques. Dans une population d'enfants maniaques bipolaires les études rapportent 57 à 98 % d'ADHD en comorbidité. Par contre, dans une population d'enfants ADHD, la comorbidité avec les états bipolaires est de 11 à 22 % (Angold et al., 1999 ; Carlson, 1998 ; Singh et al., 2006). Objectif : Affiner « une sémiologie développementale » et le diagnostic différentiel ADHD/Bipolarité Méthode : Étude qualitative avec observation et « anamnèse sémiologique » détaillée d'un maximum de micro-signes ; échantillons: 14 enfants (5 à 10 ans) et 7 adultes (20 à 37 ans) avec ADHD seul et 170 enfants (2 à 10 ans) et 55 adultes (19 à 61 ans) avec des caractéristiques bipolaires (selon le DSM IV). Résultat : Proposition d'un "tempérament maniaque bipolaire simple" en 7 axes sémiologiques : 1. forme super-énergétique, 2. clinique du sommeil, 3. "mal-être en situation d'être seul", 4. labilité émotionnelle, 5. excitabilité-désinhibitions, 6. prépondérance de l'attention divergente sur l'attention convergente, 7. tendance à l'hyperactivité. L'ADHD ne comporte que 1, 6 et 7. Réf.: « Bipolarité et ADHD. Recherche sémiologique : continuum développemental de la petite enfance à l'âge adulte et diagnostic différentiel », La Psychiatrie de l'enfant, vol. 55/2012, in press. [less ▲]

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See detailHow asteroseismology can help to precisely constrain properties of planet-host stars
Salmon, Sébastien ULg; Montalban Iglesias, Josefa ULg; Lanotte, Audrey ULg et al

Poster (2011, January)

Nowadays more than 500 exoplanets have been discovered, mainly studied by radial velocity and transit measurements. Precise knowledge on their characteristics is crucial to develop theories of planetary ... [more ▼]

Nowadays more than 500 exoplanets have been discovered, mainly studied by radial velocity and transit measurements. Precise knowledge on their characteristics is crucial to develop theories of planetary formation and evolution. In that aim, not only star and planet(s) masses but also the evolutionary stage of systems are needed. From radial velocity measurements one has to assume the inclination and the stellar mass of the system to disentangle the mass of the planet. When transit is observable, one can measure the ratio of planetary and stellar radii. Finally, the degree of evolution of the system is determined by the one of the star. Thus the host star must be well known to obtain a full set of system properties. However, determination of stellar parameters such as the mass, radius and its evolution from classical observables (Teff, log g, [Fe/H]) suffers of large uncertainties. This is particularly true for dwarf stars on the Main Sequence. Fortunately we can obtain better constrains with the help of asteroseismology. That latter approach probes the stellar properties through observation of oscillations present in stars. With the launches of high-precision photometry space missions, CoRoT and Kepler, we are now able to detect oscillations in a huge number of stars. In particular Kepler photometry, primarily intended to detect transits of planet, can give accurate stellar parameters of planetary systems as it also affords to make [less ▲]

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See detailTowards laser cooling of Iron Atoms
Huet, Nicolas ULg; Krins, Stéphanie ULg; Bastin, Thierry ULg

Poster (2011)

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