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See detailNovel HDAC/DNMT twin inhibitors interfere with angiogenesis
Shiva Shankar, Thammadihalli Veerasangaiah ULg; Sulka, Béatrice; Blacher, Silvia ULg et al

Poster (2010)

DNA methylation and histone deacetylation are two key epigenetic modifications that play central role in regulation of gene expression. Several studies have shown that histone deacetylases (HDAC) and DNA ... [more ▼]

DNA methylation and histone deacetylation are two key epigenetic modifications that play central role in regulation of gene expression. Several studies have shown that histone deacetylases (HDAC) and DNA methyltransferases (DNMT) inhibitors are potent antiangiogenic compounds. Though combination of HDAC and DNMT inhibitors are now being examined in clinical trials of hematological malignancies, very little work has been done to understand the effect of this combination on normal and tumoral angiogenesis. We have designed and tested a family of twin drugs with intrinsic HDAC and DNMT inhibitory activities in relevant models of angiogenesis in vitro (endothelial cells, pericytes and the 3D aortic ring assay) and in vivo (the chick chorioallantoic membrane assay). We have identified a lead compound having quantifiable antiangiogenic effect without cytotoxicity associated with increased global acetylation and decreased DNA methylation levels. This compound is presently used to develop effective approaches to treat cancer by modulating the process of angiogenesis. [less ▲]

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See detailSpatio-temporal patterns of preys and wastes moved by ants within the nests
Diez, Lise; Lejeune, Philippe ULg; Deneubourg, Jean-Louis et al

Poster (2010)

Living in society in a restricted and confined nest implies important organisational issues. Ants have to control food supply for the whole colony as well as nest defence but they also have to manage ... [more ▼]

Living in society in a restricted and confined nest implies important organisational issues. Ants have to control food supply for the whole colony as well as nest defence but they also have to manage everyday life tasks such as waste rejection. Within the nest, ants are faced with different items that have to be used or rejected regarding colony needs. We study whether they can discriminate between three types of items (building material, nestmate cadaver or prey) and accordingly adapt the spatio-temporal distribution of these items. Therefore, we used colonies of the ant Myrmica rubra settled in a 2-dimensional space and introduced different items in the nest centre. We show that each item triggers a specific cascade of behaviour. We observed important differences in rejection time: building items were removed within a few minutes and cadavers after a few hours while preys could be kept in the nest for a day or more. Furthermore, the movement of items by ants leads to specific spatio-temporal patterns. Building items were removed with a straight trajectory from the centre to the exit of the nest. Ant cadavers that could bear pathogens showed a trajectory avoiding and moving away from larvae that are potentially more sensitive to diseases. The moving of preys headed an oscillating pattern: these items were alternatively taken on larvae for consumption and then moved away from them, until final rejection. This specific pattern may be due to the coupled effects of groups of ants acting alternatively to feed larvae and reject waste. In the case of cadavers and building items, only undertaking ants may be active. These results suggest that each ant is able to discriminate and interact with each other leading at the collective level to a complex cascade of behaviour. [less ▲]

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See detailThermodynamic and Kinetic Contributions to Stability Adaptation in a Psychrophilic Alpha-amylase
Cipolla, Alexandre; D'Amico, Salvino; Feller, Georges ULg

Poster (2010)

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See detailEffects of methionine sources in interaction with dietary protein content on performance and oxidative status of broiler chickens
Swennen, Q.; Buyse, Johan; Mercier, Yves et al

Poster (2010)

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See detailAnts’ survival and waste management in Myrmica rubra nests
Diez, Lise; Lejeune, Philippe ULg; Detrain, Claire

Poster (2010)

Sociality increases risks of disease transmission as genetically related individuals live in a confined environment. Therefore, social insects developed specific defences against pathogens by showing ... [more ▼]

Sociality increases risks of disease transmission as genetically related individuals live in a confined environment. Therefore, social insects developed specific defences against pathogens by showing hygienic behaviours such as the rejection of cadavers and other wastes. We investigated if the undertaking and waste management is actually an efficient way of increasing ants’ survival and of limiting pathogens transmission. First, we observed the survival curve of ant colonies that were prevented from rejecting their dead nestmates outside the nest. Colonies that were forced to keep their dead inside the nest showed increased mortality of both adults and larvae in comparison to control nests, confirming that undertaking is an effective way for improving colony’s survival. Then, we compared the rejection dynamics of single waste items (ant cadavers, preys and clay pellet) introduced into ant nests. Clay pellets were quickly rejected within 12 ± 4 minutes, cadavers were dumped outside after 139 ± 28 min and preys were eaten and rejected only after 17.3 ± 0.3 hours. Spatial localisation inside the nest also differs between different items, as most cadavers stayed far from ants’ aggregate and larvae while preys were long-eaten close to larvae and inside ants’ aggregate. These results show that cadavers and preys are managed differently before becoming contagious, thus preventing effectively pathogens transmission inside the nest. [less ▲]

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See detailCO2 culling with Influenza Containment Systems (ICS)
Kamers, B.; Everaert, Nadia ULg; Tona, K. et al

Poster (2010)

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See detailHyperfine structure splitting of molecular-iodine transitions near 716 nm
Huet, Nicolas ULg; Krins, Stéphanie ULg; Dubé, P. et al

Poster (2010)

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See detailDecadal changes of carbon dioxide in the Scheldt estuary
Borges, Alberto ULg; Middelburg, J. J.

Poster (2010)

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See detailThe 900-yr sedimentary record of Lago Thompson, Northern Chilean Patagonia
Fagel, Nathalie ULg; Nuttin, L.; Bertrand, S. et al

Poster (2010)

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See detailArtificially generating sediment incipient motion in natural conditions
Gob, Frédéric ULg; Houbrechts, Geoffrey ULg; Linares Carreté, Alba et al

Poster (2010)

Incipient motion thresholds for gravel bed rivers are studied in flumes and natural rivers. Flume studies allow variables such as channel slope, water velocity, water depth, sediment size and sediment ... [more ▼]

Incipient motion thresholds for gravel bed rivers are studied in flumes and natural rivers. Flume studies allow variables such as channel slope, water velocity, water depth, sediment size and sediment composition to be controlled. Meanwhile, in the field, the incipient motion of particles is studied in natural conditions allowing the structure of the bed and the flood characteristics to be considered. Though much less developed, an intermediate possibility also exists. By artificially accelerating near bottom velocity of the water flow in a small portion of the bed, it is possible to initiate sediment transport. This allows sediment incipient motion to be observed in natural conditions while controlling the water velocities. The Cemagref (HHLY) has developed a device which confines water flow in a small tunnel on the bottom of the riverbed. It was developed in order to create a boundary layer similar to the one generated by natural flow. Water is injected into a filter which smoothes the flow before it enters a Plexiglas tunnel where sediment motion is observed. The flow is accelerated by two large pumps that allow flow velocities of up to 2.5 m/s in a small area 40 cm long, 20 cm wide and 12 cm high. As the water flow is confined, large scale turbulence similar to that occurring in natural rivers cannot be reproduced using the device. The velocity profile in the tunnel is stable and in equilibrium with the riverbed. Sediment motion was observed using this device on three Belgian gravel bed rivers (3.5 cm <D50<8 cm). The incipient critical velocities measured were coherent in the three rivers sampled, ranging between 1.3 m/s and 1.7 m/s. A progressive increase in velocity in the tunnel permitted size selective entrainment to be observed. Analysis of the particle entrainment schemes and associated velocities allowed the role played by the armoured layer and the Di/D50 ratio to be more fully understood. Critical velocities measured using the device were also compared to critical velocities observed in natural conditions, determined during several pebble tracing campaigns. This revealed that incipient motion velocities of the largest particles recorded in artificial conditions were systematically larger than those observed in natural conditions. This demonstrates the roles played by large scale turbulence and the vertical component of the flow velocity in single particle entrainment. Due to its inherent characteristics, both of these flow components are weak in the artificial conditions generated by the device. In conclusion, our study demonstrates that this type of device is a useful tool in observing and studying incipient motion processes and, in particular, the role played by the bed structure (armouring, protrusion, etc.). However, some improvements are still required in order to more accurately measure critical velocities, allowing critical discharges to be determined. [less ▲]

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See detailSeasonal variation in the essential oil composition of Artemisia herba alba, Growing in Eastern Morocco
Imelouane, B.; El Bachiri, A.; Wathelet, Jean-Paul ULg et al

Poster (2010)

The seasonal and even the number of hours that enable plants to be exposed to sunlight, may influence the phytochemistry of the plant since some compounds may be accumulated at a particular period to ... [more ▼]

The seasonal and even the number of hours that enable plants to be exposed to sunlight, may influence the phytochemistry of the plant since some compounds may be accumulated at a particular period to respond to environmental changes. Objectifs The seasonal variation of the essential oil extracted from the aerial parts of Artemisia herba alba growing in eastern Morocco (Taforalt) has been studied. [less ▲]

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See detailTowards deterministic multipartite entanglement classes in circuit QED
Bastin, Thierry ULg; Toth, G.; Siewert, J. et al

Poster (2010)

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See detailSpatial variability of the Siphonophora along the radial Calvi-Nice (Corsican side)
Collignon, Amandine ULg; Hecq, Jean-Henri ULg; Goffart, Anne ULg

Poster (2010)

The spatial distribution of the Siphonophorae has been examined, in Occidental Mediterranean, along the radial Calvi-Nice, from Calvi up to 30 miles offshore in September 2009. The variation of the ... [more ▼]

The spatial distribution of the Siphonophorae has been examined, in Occidental Mediterranean, along the radial Calvi-Nice, from Calvi up to 30 miles offshore in September 2009. The variation of the abundance of the plankton and of the Siphonophorae was put in relation with the hydrological structures of the Liguro-Provençal front. This structure separates the coastal waters of Atlantic origin from the offshore central Mediterranean waters of deep origin. Globally, the larger abundances of Siphonophorae were present in inshore waters between the front and the coast. Both nectophores (asexual stage) and gonophores and bracts (reproductive stage) of Lensia subtilis occured only in the inshore waters. The nectophores of Chelophyes appendiculata occured at all sampling stations with no significative variation. However, the abundance of the bracts and the gonophores increases when we get closer to the coast. This allows us to hypothesize that the maximum of reproduction is located in waters close to the coast. On the other hand, the larvae abundance of calycophoran siphonophores, in the plankton samples, increase from the coastal waters to the offshore waters with a maximum of abundance at the station located at 25 miles offshore. That contradiction could be explained by plankton net avoidance of small larvae, by current transport or by variable hatching success at the various stations. The larvae of physonect siphonophores are more often found offshore. [less ▲]

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See detailUsing time-dependent reference profiles for an instability analysis of an evaporating binary liquid layer
Machrafi, Hatim ULg; Rednikov, Alexey; Colinet, Pierre et al

Poster (2010)

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See detailResidual stress measurement in dental prostheses by hole-drilling.
Mainjot, Amélie ULg; Schajer, Gary; Vanheusden, Alain ULg et al

Poster (2010)

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See detailThe Venus OH Nightglow Distribution
Soret, Lauriane; Gérard, Jean-Claude ULg; Piccioni, G. et al

Poster (2010)

The study shows that the OH emission is highly variable, ranging from less than 20 kR to about 2 MR. The peak brightness appears to decrease away from the antisolar point even if the variability at a ... [more ▼]

The study shows that the OH emission is highly variable, ranging from less than 20 kR to about 2 MR. The peak brightness appears to decrease away from the antisolar point even if the variability at a given location is very strong. By contrast, although the OH peak altitude also appears to be variable, it shows no dependence with the location on the nightside of Venus. Some correlation between simultaneous observations of the intensity of the OH and the O2(a1Δ) emissions has also been detected, presumably because atomic oxygen is a common precursor to the formation of O2(a1Δ) and O3, whose reaction with H produces excited OH. Anyway, it is important to keep in mind that horizontal transport plays an important role in the redistribution of photochemically produced species such as O, O3 and minor long-lived species and possibly explains some of the variability of the OH emission and its brightness relative to O2(a1 ). [less ▲]

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See detailL’extraction des huiles essentielles par micro-ondes : Quels avantages ?
Ramdani, M.; Benchat, N.; Amhamdi, H. et al

Poster (2010)

Detailed reference viewed: 153 (13 ULg)
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See detailA 500-yr record of Northern Patagonian environmental changes: Lago Plomo and Lago Bertrand
Fagel, Nathalie ULg; Brix, J.; El Ouahabi, M. et al

Poster (2010)

Detailed reference viewed: 26 (4 ULg)
Peer Reviewed
See detailInfluence of operating conditions on the gaseous emissions related to urban residual sludge convective drying
Fraikin, Laurent ULg; Herbreteau, Benjamin; Chaucherie, Xavier et al

Poster (2010)

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See detailLate Holocene environmental changes recorded in the sediments of Lago Thompson, Northern Chilean Patagonia
Fagel, Nathalie ULg; Nuttin, L.; Bertrand, S. et al

Poster (2010)

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Peer Reviewed
See detailSimultaneous quantification os asiaticoside, asiatic acid, madecassoside and madecassic acid in leaves of Centella asiatica (L.) urb.
Rafamantanana, M. H.; Rozet, Eric ULg; Raoelison, G. E. et al

Poster (2010)

Detailed reference viewed: 104 (10 ULg)
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See detailEnvironmental changes in two lakes of Northern Patagonia (Chile): A 1000 yr reconstruction based on pollen and charcoal.
Vargas, N.; Torres, L.; Araneda, A. et al

Poster (2010)

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See detailEffets du mode d’extraction des huiles essentielles sur l’efficacité de l’inhibition de la corrosion
ramdani, M.; Benchat, N.; Amhamdi, H. et al

Poster (2010)

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See detailTechnique d’extraction et activité antibactérienne des huiles essentielles
Benchat, N.; Amhamdi, H.; Wathelet, Jean-Paul ULg et al

Poster (2010)

Detailed reference viewed: 90 (9 ULg)
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See detailTraces metal inputs in the Misten bog (East Belgium): Level of contamination and spatial variability
Allan, M.; Fagel, Nathalie ULg; De Vleeschouwer, F. et al

Poster (2010)

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See detailA 14,000 yr elemental and lead isotopis record in a peat core in the south of Poland –results and interpretation
Tudyka, K.; De Vleeschouwer, F.; Pazdur, A. et al

Poster (2010)

Detailed reference viewed: 38 (4 ULg)
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See detailAtmospheric lead deposition in an ombrotrophic peat bog of Southern Poland
Fiałkiewicz-Kozieł, B.; De Vleeschouwer, F.; Smieja-Król, B. et al

Poster (2010)

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See detailA paleorecord of atmospheric lead deposition in France. New data from “La Godivelle” peat bog (Puy de Dôme)
De vleeschouwer, F.; Mattielli, N.; Renson, V. et al

Poster (2010)

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See detailBenthic remineralisation in the Northeast European Continental margin (Northern Biscay Bay)
Suykens, K.; Schmidt, S.; Delille, Bruno ULg et al

Poster (2010)

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See detailSpecies effect on the water use efficiency of a mixed forest of beech (Fagus sylvatica L.), Douglas fir (Pseudotsuga menziesii (Mirb.) Franco) and silver fir (Abies alba Mill.) in Belgium Ardennes
Soubie, Rémy; Heinesch, Bernard ULg; Aubinet, Marc ULg et al

Poster (2010)

Induced by climate change, intensity and frequency of droughts should be more important for the next century. How does water availability affect the physiology of woody plants at the species and stand ... [more ▼]

Induced by climate change, intensity and frequency of droughts should be more important for the next century. How does water availability affect the physiology of woody plants at the species and stand scale? Carbon and water vapour fluxes measurements of a mixed forest (deciduous and coniferous) were performed for over ten years by the eddy covariance method in Belgian Ardennes (Aubinet et al, 2001) as a part of the CarboEurope project. Whereas carbon fluxes have been analyzed in detailed and good estimations of the Net Ecosystem Exchange (NEE) and Gross Primary Production (GPP) were obtained, a thorough analysis of water vapour fluxes remains to be done. Improving analysis of water vapour fluxes and monitoring species transpiration will contribute to the estimation of the water use efficiency, WUE, at both the species and stand scale. The WUE well characterizes the vegetation productivity and ecosystem response to environmental factors. It also allows evaluating the sensitivity of temperate woody species to drought. The species concerned are beech (Fagus sylvatica L.), Douglas fir (Pseudotsuga menziesii (Mirb.) Franco) and silver fir (Abies alba Mill.). Since summer 2009 we monitor and analyze each species water use by measuring sap flow with the thermal dissipation method (Granier, 1987). Results at the species level will then be upscaled and compared to stand water vapour fluxes measurements obtained by the eddy covariance methodology. Transpiration of each species will be analyzed in relation with their own phenological and ecophysiological attributes, ecosystem soil and atmospheric conditions, to clarify among others their behaviour in case of water deficit. Data are actually analysed, the presented results will concern the 2009, and a part of 2010 growing season. [less ▲]

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See detailDevelopment of a new crossbred based evaluation for carcass quality of Piétrain boars in the Walloon Region of Belgium
Dufrasne, Marie ULg; Hammami, Hedi ULg; Jaspart, Véronique et al

Poster (2010)

The aim of this study was to develop a genetic evaluation model to estimate the genetic merit of Piétrain boars for some carcass quality traits. These boars are now evaluated on performances recorded on ... [more ▼]

The aim of this study was to develop a genetic evaluation model to estimate the genetic merit of Piétrain boars for some carcass quality traits. These boars are now evaluated on performances recorded on their crossbred progeny fattened in a central test station. Data provided by the on-farm performance recording system were utilized in this study. Traits analysed were backfat thickness (BF) and lean meat percentage (%meat). The data file contains 60 546 records measured on pigs between 150 and 300 days of age. Model developed was a multitrait animal model. Fixed effects were sex, contemporary groups and heterosis, modeled as regression on heterozygosity. Random effects were additive genetic and permanent environment, modeled by random regressions using linear splines, and residual. Variance components were estimated by restricted maximum likelihood (REML) method on random samples of the total dataset and then confirmed by a Gibbs sampling algorithm on the total dataset. Fit of the model was tested by computing residuals from a BLUP (Best Linear Unbiased Prediction) evaluation. BF and %meat have a high heritability that increase with age. These two traits are also highly genetically correlated. Mean residuals are not significantly different from zero for both traits. Given that BF and %meat had high heritability, genetic improvement of carcass quality is possible by selection on these two traits. Like residuals are close to zero for both traits, it seems that model developed explain a great proportion the variance in each traits. [less ▲]

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See detailImproving the grinding performance in ball mills with a conductive and inductive sensor
Köttgen, Axel ULg; de Haas, Bernard; Keshav, Pratish et al

Poster (2010)

A series of tests were conducted in a South African concentrator on the secondary grinding mill. The results were analysed and provided showed the importance of selecting an optimum density and filling ... [more ▼]

A series of tests were conducted in a South African concentrator on the secondary grinding mill. The results were analysed and provided showed the importance of selecting an optimum density and filling degree of the mill. Moreover, a Sensomag (r) is installed on this mill and the surveys showed that an increase of the density was improving the mixing of balls in the pulp and increasing the grinding performance. [less ▲]

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See detailChemical Composition and Antimicrobial Activity of the Essential Oil of Myrtus communis L. from Algeria
Brada, M.; Hennia, A.; Nemmiche, S. et al

Poster (2010)

This study deals with the valorisation of medicinal and aromatic plants of the Algerian flora, in order to find new bioactive natural products. Myrtus communis essential oil obtained by hydrodistillation ... [more ▼]

This study deals with the valorisation of medicinal and aromatic plants of the Algerian flora, in order to find new bioactive natural products. Myrtus communis essential oil obtained by hydrodistillation was investigated by capillary gas chromatography and gas chromatography/mass spectrometry. Twenty-seven volatile compounds were identified in the leaves essential oil; the major components were: -pinene (23.5 %), limonene (22.9 %), 1,8-cineole (16.1 %), linalool (13.0%), linalyl acetate (10.9%) and geranyl acetate (4.6%). The antibacterial activity of essential oils extracts was evaluated by the diffusion method and by the dilution method in liquid medium on pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Salmonella sp, Proteus sp and Klebsiella sp). [less ▲]

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See detailEtude de la composition chimique de l'huile essentielle du lentisque de la région orientale du Maroc
Aouinti, F.; Amhamdi, H.; Wathelet, Jean-Paul ULg et al

Poster (2010)

Le lentisque ou pistachier appartient à la famille des Anacardiacées. C'est un arbuste poussant dans les sites arides de la région méditerranéenne (Asie, Europe, Afrique). On l'appelle aussi arbre à ... [more ▼]

Le lentisque ou pistachier appartient à la famille des Anacardiacées. C'est un arbuste poussant dans les sites arides de la région méditerranéenne (Asie, Europe, Afrique). On l'appelle aussi arbre à mastic car sa sève est utilisée pour la réalisation d'une gomme à odeur prononcée. Son huile essentielle est obtenue par hydrodistillation et analysée par chromatographie en phase gazeuse. L'objectif ce ce travail est l'étude de la composition chimique de l'huile essentielle du lentisque récolté de différentes zones de la région orientale du Maroc. [less ▲]

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See detailDiagenèse osseuse et genèse de nodules phosphatés, associés aux sédiments fluvio-lacustres de sites à hominidés miocène (Kenya)
DERICQUEBOURG, P.; PERSON, A.; SEGALEN, L. et al

Poster (2010)

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See detailA double-cartridge SPE-HPLC-UV method for monitoring a humanfriendly anticancer in plasma: Ketoglutarate levels in metastatic carcinoma
Michail, K.; Rozet, Eric ULg; Hubert, Philippe ULg et al

Poster (2010)

We present a fully validated HPLC-UV assay for the concurrent quantification of ketoglutaric acid and hydroxymethylfurfural, a ‘targeted therapy’ composition inducing a synergistic metabolic distress to ... [more ▼]

We present a fully validated HPLC-UV assay for the concurrent quantification of ketoglutaric acid and hydroxymethylfurfural, a ‘targeted therapy’ composition inducing a synergistic metabolic distress to the tumoral microenvironment. The analytes were exclusively extracted from the biomatrix via a combined-cartridge solid phase extraction assembly. The method is based on derivatizing both analytes with 2-nitrophenylhydrazine directed to their chemically divergent but commonly occurring carbonyl function. The reaction is kinetically catalyzed. Acidifying the buffered eluate post-extraction is critical for the feasibility of the reaction. The chromatographic separation is successfully accomplished on octyl columns in less than 15 min at 330 nm using 0.028% TFAA-methanol-acetonitrile (58:32:10, v/v) as eluant. The assay was validated using the concept of accuracy profile. The selectivity of the method was demonstrated in pre- and post-dosed patients from a pilot study. Quality control samples were prepared and analyzed during the routine use of the method. Life samples collected from patients enduring oesophageal and breast carcinoma with lung metastases were monitored for ketoglutarate in a trial to correlate its plasma levels with the malignancy. [less ▲]

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See detailMitral valve dynamics in a closed-loop model of the cardiovascular system
Paeme, Sabine ULg; Chase, J. Geoffrey; Hann, Christopher et al

Poster (2009, December 17)

A cardiovascular and circulatory system (CVS) model has been validated in silico, and in several animal model studies. It accounts for valve dynamics by means of Heaviside function to simulate “open on ... [more ▼]

A cardiovascular and circulatory system (CVS) model has been validated in silico, and in several animal model studies. It accounts for valve dynamics by means of Heaviside function to simulate “open on pressure, close on flow” law. Thus, it does not consider the real time scale of the valve aperture and thus doesn’t fully capture valve dysfunction. This research couples the CVS model with a model describing the progressive aperture of the mitral valve. [less ▲]

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See detailHydrolysis of starch by sorghum malt for maltodextrin production
Ba, Khady ULg; Destain, Jacqueline ULg; Thonart, Philippe ULg

Poster (2009, December 16)

Maltodextrin is a mixture of saccharides with a molecular weight between polysaccharides and oligosaccharides with DE lower than 20. Maltodextrin is more soluble in water than native starches, also is ... [more ▼]

Maltodextrin is a mixture of saccharides with a molecular weight between polysaccharides and oligosaccharides with DE lower than 20. Maltodextrin is more soluble in water than native starches, also is cheaper in comparison with other major edible hydrocolloids. Maltodextrin is obtained by moderate enzymatic or acidic hydrolysis of starch. The hydrolysis of starch, catalyzed by amylases, is the most important commercial enzyme process. The hydrolyzed products are widely applied in food, paper and textile industries. Because of the increasing demand for these enzymes in various industries, there is enormous interest in developing enzymes with better properties, such as raw starch-degrading amylases suitable for industrial applications and their cost-effective production techniques. Sorghum (Sorghum bicolor) is a widely grown crop in Africa. Obtaining enzymes from sorghum requires a transformation. The objective of this study was application of sorghum amylase for maltodextrin. Sorghum seeds were supplied by the ISRA (Bambey, Senegal). Seeds were germinated in the laboratory at 30°C for 72 h and the sorghum malt was dried at 40°C for 48 h. Corn starch (from Roquette, France) hydrolysis was assayed in a bioreactor of 2 l at a temperature of 65°C gently stirred. Raw starch was slurried in water (30% w/v) and sorghum malt was introduced, chloride calcium was added, pH was adjusted to 6. Maltodextrin was characterized in term of the dextrose equivalent (DE) during the hydrolysis. The yield of hydrolysis was evaluated by soluble solids (° BRIX) at different hydrolysis time. The glucose concentration released was measured by DNS method (Miller method). [less ▲]

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See detailLA STEAM EXPLOSION : PRINCIPE ET ACTION SUR LES MATERIAUX LIGNOCELLULOSIQUES
Jacquet, Nicolas ULg; Blecker, Christophe ULg; Paquot, Michel ULg

Poster (2009, December 16)

La steam explosion est un procédé thermomécanochimique qui va permettre la déstructuration de la matière lignocellulosique par l’action combinée de la chaleur issue de la vapeur, des hydrolyses induites ... [more ▼]

La steam explosion est un procédé thermomécanochimique qui va permettre la déstructuration de la matière lignocellulosique par l’action combinée de la chaleur issue de la vapeur, des hydrolyses induites par la formation d’acides organiques et du cisaillement résultant de la chute brutale de pression. Le procédé est composé de deux phases distinctes. D’une part, le vapocraquage qui consiste à faire pénétrer par diffusion, puis à condenser, la vapeur sous haute pression à l’intérieur de la structure du matériau. L’eau condensée à température élevée va initier l’hydrolyse des groupements acétyles contenus dans les xylanes et induire la formation d’acides organiques. Selon la sévérité des conditions (pression, température), les acides vont catalyser l’hydrolyse des fractions hémicellulosiques, induire des modifications dans la structure des lignines et modifier le degré de cristallinité de la fraction cellulosique. D’autre part, la décompression explosive. Cette phase est provoquée par une chute brutale de pression qui va entraîner la revaporisation d’une partie de l’eau condensée. L’expension brutale de la vapeur va induire des forces de cisaillement qui vont modifier les propriétés physiques (granulométrie, surface spécifique, rétention d’eau…) du matériau. [less ▲]

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See detailThe diversity of clostridial hydrogenases revealed by genome sequencing projects
Calusinska, Magdalena ULg; Wilmotte, Annick ULg; Joris, Bernard ULg

Poster (2009, December 15)

Molecular hydrogen is a key intermediate in metabolomic interactions of a wide range of microorganisms. Hydrogen is also regarded as a key component in future energy systems as it is a sustainable, clean ... [more ▼]

Molecular hydrogen is a key intermediate in metabolomic interactions of a wide range of microorganisms. Hydrogen is also regarded as a key component in future energy systems as it is a sustainable, clean, and transportable energy carrier. Some microorganisms can produce hydrogen during a reversible reduction of protons to dihydrogen, a reaction which is catalyzed by the enzyme hydrogenases. On the basis of their bimetallocenter composition, hydrogenases are divided into three main groups, phylogenetically not related: [NiFe] hydrogenases, [Fe] only hydrogenases and FeS cluster free hydrogenases. The latter were described in methanogenic Archaea only. [NiFe] hydrogenases, composed of at least two subunits are well characterized and widely distributed between Archaea and Bacteria. However, only a few representatives of Clostridium sp. possess this type of enzyme. On the other hand, much less is known about the [Fe] only hydrogenases, that are usually monomeric enzymes and restricted to Bacteria and a few eukaryotic species. Genome sequencing projects gave a completely new insight into the diversity of forms of putative [Fe] only hydrogenases within the genus Clostridium. With the use of bioinformatic tools, we have described the unusual modularity of forms of these enzymes, from monomeric to tetrameric with a different number of accessory domains reacting with diverse redox partners. This fact seems to support the central role of hydrogenases in cell metabolism and quick adaptation of the host to changing environmental conditions. Moreover, the presence of multiple putative operons encoding for multisubunit [FeFe] hydrogenases is highlighting the fact that hydrogen metabolism is very complex in the Clostridium genus. [less ▲]

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See detailCobalt-mediated radical polymerization (CMRP) and coupling reaction (CMRC): mechanistic advances ans synthetic opportunities
Debuigne, Antoine ULg; Poli, Rinaldo; De Winter, Julien et al

Poster (2009, December 14)

Detailed reference viewed: 34 (10 ULg)
See detailSynthesis of novel amphiphilic mikto-arm star-shaped copolymers
Riva, Raphaël ULg; Lazarri, Wenda; Billiet, Leen et al

Poster (2009, December 14)

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See detailCharacterization of spatio-temporal organization of slow waves during human NREM sleep
Schrouff, Jessica ULg; Leclercq, Yves ULg; Foret, Ariane et al

Poster (2009, December 14)

Sleep is a behavior commonly observed in a large number of animal species. However, neuroscientists still poorly understand the meaning of this loss of consciousness absolutely needed for life. In the ... [more ▼]

Sleep is a behavior commonly observed in a large number of animal species. However, neuroscientists still poorly understand the meaning of this loss of consciousness absolutely needed for life. In the present work, we established different methods to characterize the Slow Wave Sleep most recognizable patterns: the Slow Waves (SWs). Since the anatomical structure of white matter tracts that connect various brain regions is not random and thus must constraint the propagation of waves (Hagmann et al., 2008), our basic hypothesis was that large white matter bundles would bias the propagation of SW along specific patterns, which could be identified in homogeneous clusters of waves. To investigate our hypothesis, SWs were detected automatically on the three first periods of SWS using an algorithm based on Massimini et al., 2004. They were then clustered using a two steps procedure involving a hierarchical clustering based on delay maps and a k-means clustering based on the SWs potential in a given time interval around the maximum power of the SW negative peak. To compute the relevance of the final clusters, a mathematical criterion was implemented as well as a visual check. Results of the multisubjects study showed that only bad quality and small clusters could be obtained, suggesting that there is no particular organization of SWs across the night and inforcing the hypothesis that SWs are local phenomena, each one decreasing the homeostatic pressure in only one specific area. [less ▲]

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See detailAFM-based mechanical testing of electrospun PCL fibers
Croisier, Florence ULg; Duwez, Anne-Sophie ULg; Jérôme, Christine ULg et al

Poster (2009, December 14)

Poly(ε-caprolactone)(PCL forms a part of the aliphatic polyesters; the biodegradable and biocompatible character of these polymers makes them outstanding candidates for short-to medium-term biomedical ... [more ▼]

Poly(ε-caprolactone)(PCL forms a part of the aliphatic polyesters; the biodegradable and biocompatible character of these polymers makes them outstanding candidates for short-to medium-term biomedical applications, especially in the form of nanometric fibers,as their assembly mimics the extracellular matrix structure. However, a prerequisite to their application as nanofibrous biomaterial scaffolds is the investigation of their mechanical strength. In the present study, PCL fibers produced by electrospinning were individually tested using an AFM-based nano-scale three-point bending technique. [less ▲]

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See detailSuperhydrophobic surfaces by electrospinning of polymer mixtures
Grignard, Bruno ULg; Vaillant, Alexandre; De Coninck, Joel et al

Poster (2009, December 14)

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See detailAdherent functional coatings from readily available acrylates
Cecius, Michaël ULg; Jérôme, Christine ULg

Poster (2009, December 14)

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See detailApplication of molecular techniques to monitor the evolution of bacterial consortia composed of Clostridium sp. in a hydrogen producing bioreactor
Calusinska, Magdalena ULg; Savichtcheva, Olga; Joris, Bernard ULg et al

Poster (2009, December 11)

Our current dependence on fossil fuels as the primary energy source contributes to global climate change, environmental degradation and health problems. Hydrogen offers a tremendous potential as a clean ... [more ▼]

Our current dependence on fossil fuels as the primary energy source contributes to global climate change, environmental degradation and health problems. Hydrogen offers a tremendous potential as a clean, renewable energy currency and it is compatible with electrochemical and combustion processes for energy conversion without producing carbon – based emissions. Many microorganisms, especially photosynthetic as well as facultative and anaerobic bacteria have been reported to produce large amounts of hydrogen from soluble and insoluble biomass. Clostridia, being obligate anaerobes, are capable of biogas production during ‘dark fermentation’ of a wide range of carbohydrates. In this ARC project, entitled Micro – H2 we have focused on a new direction in bio – hydrogen production systems which is the use of mixed cultures of microorganisms (consortia). We expect that the combination of complementary metabolisms could significantly increase the efficiencies of mixed systems compared to monocultures. However, a few fundamental studies need to be carried out in order to investigate and improve the stability of microbial populations involved in the processes. It is now recognised that molecular microbial ecology tools provide the scientific basis to monitor the processes used in environmental biotechnology. To characterize the diversity of bacterial communities, quantitative techniques such as Real – Time Quantitative PCR and FISH (Fluorescence in situ hybridization) and semi – quantitative DGGE (Denaturing Gradient Gel Electrophoresis) have been optimized and applied on different bioreactor samples. This approach enabled for the temporal monitoring of the evolution of bacterial consortia, both in terms of species dominance and their metabolic activity. Molecular analysis of bacterial consortia allowed for careful examination of interactions between different bacterial species within a consortium, which is crucial in the stabilization of the hydrogen production process. [less ▲]

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See detailCyanobacterial 
molecular 
diversity 
and distribution 
in 
microbial 
mats from 
antarctic 
lakes
De Carvalho Maalouf, Pedro ULg; Lambion, Alexandre ULg; Zakhia, Frédéric et al

Poster (2009, December 11)

The coastal deglaciated areas of Antarctica hold lakes and other water bodies with a wide spectrum of limnological conditions. Aquatic habitats offer milder conditions to the microorganisms, which are the ... [more ▼]

The coastal deglaciated areas of Antarctica hold lakes and other water bodies with a wide spectrum of limnological conditions. Aquatic habitats offer milder conditions to the microorganisms, which are the only permanent inhabitants of this glacial desert. Among them, cyanobacteria are the first photosynthetic colonisers, sometimes forming thick, cohesive and pigmented benthic mats. In the frame of the BELSPO AMBIO project (Antarctic Microbial BIOdiversity, influence of geographical and ecological factors, www.ambio.ulg.ac.be), we have obtained benthic mat samples coming from lakes from various coastal regions of the continent (MERLIN 2007 and BELARE 2007 field campaigns and by collaborations). We have investigated cyanobacterial molecular diversity via Polymerase Chain Reaction and Denaturating Gradient Gel Electrophoresis (PCR-DGGE) on a set of 80 samples. We couple the numerical analysis of the obtained band patterns with the phylogenetic analysis of the sequences, and by using multivariate analysis, we will assess the role of the ecological and geographical factors shaping the distribution and the diversity of cyanobacteria. Preliminary results of the analysis of 13 samples seem to indicate that lakes separated by a small distance have different cyanobacterial communities, highlighting the importance of ecological factors. Fifty per cent of the obtained Operational Taxonomic Units (OTUs) are potentially endemic to Antarctica while others seem to have a global distribution. The completed study will give us a wide scale view on the distribution and the diversity of cyanobacteria in two biogeographical zones: Continental Antarctica and Maritime Antarctica. Finally, our studies will supply new data and arguments for the ongoing “everything is everywhere, but the environment selects” debate concerning microbial biogeography. [less ▲]

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See detailComparative study of Murid gammaherpesvirus 4 infection in mice and in its natural host, the bank voles.
François, Sylvie ULg; Vidick, Sarah ULg; Koteja, Pawel et al

Poster (2009, December 11)

Gammaherpesviruses are the archetypes of persistent viruses that have been identified in a range of animals from mice to man. They are host-range specific and establish persistent, productive infections ... [more ▼]

Gammaherpesviruses are the archetypes of persistent viruses that have been identified in a range of animals from mice to man. They are host-range specific and establish persistent, productive infections of immunocompetent hosts. Thus, infected individuals simultaneously both elicit antiviral protective immune response and secrete infectious virions. The best studied gammaherpesviruses are Human herpesvirus 4 and Human herpesvirus 8. As these viruses have no well-established in vivo infection model, related animal gammaherpesviruses are an important source of information. We are studying Murid herpesvirus 4 (MuHV-4), a virus that has originally been isolated from bank voles (Myodes glareolus). Although MuHV-4 has not been isolated from house mice (Mus musculus), infection of inbred laboratory mouse strains is commonly accepted as a good model for studying gammaherpesviruses in vivo. It has however never been possible to monitor viral reexcretion and virus transmission in this species suggesting that this model could be imperfect. In this study, we therefore characterized MuHV-4 infection in its natural host, the bank voles, through classical virological methods but also through global luciferase imaging for an anatomical complete view of the infection. Results obtained show that, after intra-nasal infection, the natural route of infection is similar in mice and voles. Following nasal productive infection, the virus spreads to the lung where the infection is accompanied by massive cellular infiltrates. By opposition to extensive viral replication observed in mice, the different analyses indicated that the viral replication was ~1000 fold lower in bank voles. This lower replication did however not affect colonization of latency sites in superficial cervical lymph nodes and spleen as measured by real-time PCR quantification of viral genomes in these organs. In conclusion, this study revealed that MuHV-4 can experimentally infect bank voles, the supposed natural host, but with a lower replicative power. As, gammaherpesvirus epidemiology indicates that transmission correlates with the latent load, our results suggest that gammaherpesviruses may have evolved to infect their hosts without extensive lytic spread. In the future, establishment of experimental transmission in a population of Myodes glareolus should help us to better understand mechanisms used by gammaherpesviruses to evade immune response. [less ▲]

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See detailHydrological modeling of the EU Nitrates Directive Actions Programme:
Sohier, Catherine ULg; Dautrebande, Sylvia; Degre, Aurore ULg

Poster (2009, December 11)

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See detailEx vivo bioluminescent detection of alcelaphine herpesvirus 1 infection during malignant catarrhal fever induced in rabbits
Dewals, Benjamin G ULg; Myster, Françoise ULg; Massart, François et al

Poster (2009, December 11)

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla ... [more ▼]

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. Experimentally, WD-MCF can be reproduced in rabbits. The lesions observed are very similar to those described in natural host species. Recently, we demonstrated that WD-MCF induced by AlHV-1 in rabbits is associated with the proliferation of CD8+ cells supporting a latent type of infection. In the present study, we investigated whether the virus could be detected ex vivo in the tissues of rabbits developing WD-MCF. Taking advantage of the recent cloning of the AlHV-1 genome as a bacterial artificial chromosome (BAC), we produced a recombinant plasmid encoding a firefly luciferase (LUC) expression cassette inserted in a non-coding region of the AlHV-1 genome. In vitro, the reconstituted AlHV-1 LUC strain replicated comparably to the parental strain in permissive cells and was able to induce a bioluminescent signal. In vivo, rabbits infected with the AlHV-1 LUC strain developed WD-MCF similarly to the parental wild-type strain with hyperthermia, increased CD8/CD4 ratio and viral genomic charge over time in PBMC and in lymph nodes at time of death. To identify the presence of AlHV-1 infection ex vivo, various organs of infected rabbits developing WD-MCF were analysed by bioluminescent imaging. Luciferase activity could be detected macroscopically at the time of death in most of analyzed organs including lung, popliteal and mesenteric lymph nodes, spleen, liver, kidney and appendix. Infectious virus could be isolated following co-cultures of lymph node and permissive cells, and the isolated virus retained the ability to induce a bioluminescent signal. In conclusion, we produced an AlHV-1 LUC recombinant and we were able to detect the AlHV-1 infection ex vivo in many organs at the time of death. [less ▲]

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See detailRétroconversion automatique du Französisches Etymologisches Wörterbuch (FEW)
Renders, Pascale ULg

Poster (2009, December 09)

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See detailCross-linked pH sensitive polymer micelles for drug delivery systems
Cajot, Sébastien ULg; Jérôme, Christine ULg

Poster (2009, December 08)

Over the last decade, polymer micelles attracted an increasing interest in drug pharmaceutical research because they could be used as efficient drug delivery systems. Micelles of amphiphilic block ... [more ▼]

Over the last decade, polymer micelles attracted an increasing interest in drug pharmaceutical research because they could be used as efficient drug delivery systems. Micelles of amphiphilic block copolymers are supramolecular core-shell type assemblies of tens of nanometers in diameter. In principle, the micelles core is usually constructed with biodegradable hydrophobic polymers such as aliphatic polyesters, e.g. poly(ɛ-caprolactone) (PCL), which serves as a reservoir for the incorporation of various lipophilic drugs. Water soluble poly(ethylene oxide) (PEO) is most frequently used to build the micelle corona because it is very efficient in preventing protein adsorption at surfaces and in stabilizing the micelles in the blood compartment, giving rise to particles invisible to the body defence system (so-called stealthy or long circulating particles). The tumour targeting of a cytotoxic agent refers to the passive accumulation of polymer nanocarriers to solid tumours (EPR effect) followed by active internalization in tumor cells. The internalization of the drug is required for cell death because most cytotoxic drugs act intracellularly. Accordingly, polymer micelles are usually modified by specific ligands. No-specific ligands can be used if their exposition is modulated by the pH decrease typical of tumour tissues. The release of the drug is ruled by diffusion and degradation of the biodegradable polymer used as reservoir. Even if micelles get a high stability in aqueous media thanks to their low critical micellar concentration, the dissociation of micelles is not always preserved when they are injected in the blood compartment. The cross-linking of the core of micelles by disulfide bridges will provide the stability of micelles after the administration and will release the drugs intracellularly by enzymatic breaking of disulfide bridges. This work consists in the development of new macromolecular architectures for the targeting of tumour cells. pH sensitive copolymers able to micellize so as non-specific ligand like biotin is exposed on their surface in response to pH decrease typical for tumour tissues will be synthesized by the incorporation of pH-sensitive linkers, e.g. imine benzoïc linkers. In addition, the core of these new micelles will be cross-linked by disulfide bridges to prevent dissociation around healthy cells and trigger the drug release inside tumour cells. [less ▲]

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See detailSynthesis of glucose-responsive hollow capsules
Alaimo, David ULg; Detrembleur, Christophe ULg; Auzély-Velty, Rachel et al

Poster (2009, December 07)

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See detailRépétition de non-mots et rappel sériel immédiat : Des mesures équivalentes de la mémoire à court terme verbale?
Leclercq, Anne-Lise ULg; Majerus, Steve ULg

Poster (2009, December 04)

En psychologie expérimentale et en neuropsychologie, les mesures classiques pour évaluer la mémoire à court terme verbale (MCTV) sont des tâches de rappel sériel immédiat (empan de chiffres ou de mots ... [more ▼]

En psychologie expérimentale et en neuropsychologie, les mesures classiques pour évaluer la mémoire à court terme verbale (MCTV) sont des tâches de rappel sériel immédiat (empan de chiffres ou de mots). Il a été démontré que cette même MCTV prédit les capacités de développement lexical, mais sur base d’une estimation de la MCTV à partir de tâches de répétition de non-mots. Même si ces deux procédures (répétition de non-mots, rappel sériel immédiat) sont censées mesurer la MCTV de façon équivalente, la répétition de non-mots recrute davantage de processus linguistiques tels que la segmentation phonologique et la coarticulation (Gathercole, 2006; Majerus, Van der Linden, Mulder, Meulemans, & Peters, 2004). Le but de cette étude est de déterminer dans quelle mesure ces deux types d’estimation de la MCTV sont des prédicteurs équivalents du développement lexical. Des tâches de rappel de syllabes présentées soit de manière sérielle (chaque syllabe étant séparée par une pause), soit de manière agglutinée (= répétition de non-mots) ont été administrées à des enfants de 4, 5, 6 et 8 ans (N=30 dans chaque groupe). Le niveau de vocabulaire a été évalué par le test EVIP (Dunn, Thériault-Whalen, & Dunn, 1993). Une analyse de variance sur les performances aux tâches de MCTV a montré un effet de l’âge (F(3,116)=26.87, p<.001) et un effet du type de tâche, avec de meilleures performances pour les syllabes présentées de façon agglutinée (F(1,116)=390.85, p<.001). Une analyse de régression sur le niveau de vocabulaire a indiqué qu’à la fois la répétition de non-mots et le rappel de séries de syllabes sont des prédicteurs significatifs, après contrôle de l’âge et du niveau intellectuel non-verbal. En outre, la répétition de non-mots reste un prédicteur significatif du niveau de vocabulaire après contrôle du rappel sériel de syllabes (Δ R²=.016). La relation inverse n’est pas significative. Cette étude montre que la répétition de non-mots et le rappel sériel immédiat ne reflètent pas des mesures identiques de la MCTV, et que la prédiction la plus robuste du niveau de vocabulaire est observée pour les tâches de MCTV recrutant un maximum de processus linguistiques. [less ▲]

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See detailL'influence de la fréquence d'occurrence sur l'abstraction des schémas de construction linguistiques chez les enfants dysphasiques
Leroy, Sandrine ULg; Moulin, Mélissa; Parisse, Christophe et al

Poster (2009, December 04)

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See detailRétention de l’ordre sériel en mémoire verbale à court-terme chez des adultes dyslexiques
Martinez Perez, Trecy ULg; Poncelet, Martine ULg; Majerus, Steve ULg

Poster (2009, December 04)

Les difficultés en mémoire verbale à court terme (MCTV) chez les dyslexiques sont interprétées comme le reflet de représentations phonologiques déficitaires (voir Snowling, 2000). Cependant, leurs ... [more ▼]

Les difficultés en mémoire verbale à court terme (MCTV) chez les dyslexiques sont interprétées comme le reflet de représentations phonologiques déficitaires (voir Snowling, 2000). Cependant, leurs capacités en MCTV sont généralement évaluées au moyen de tâches classiques (tâches d'empan) qui ne permettent pas de dissocier le stockage de l'information relative à l'identité des items (information « item ») du stockage de l'information concernant l'ordre de présentation de ces items (information « ordre sériel ») (Majerus et al., 2006). Or, ces deux aspects de la MCTV pourraient être différentiellement liés à l'apprentissage du langage écrit et être tous deux déficitaires dans la dyslexie. L’objectif de cette étude est de déterminer si les dyslexiques présentent des difficultés en MCTV non seulement pour l'information « item » mais également pour l'ordre sériel.  [less ▲]

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See detailThe use of an adapted model allows contributing to the “Reduction” of mice used in experimental protocols: the case of the apoE–deficient (apo E-/-) mice in a model of atherosclerosis control
Cherdon, Céline ULg; Rolin, Stéphanie; de Leval, Laurence ULg et al

Poster (2009, December 01)

Atherosclerosis is a chronic vascular disease whose development is influenced by several mediators 1. Among them, the prostanoids large family lipids generated from the metabolism of arachidonic acid by ... [more ▼]

Atherosclerosis is a chronic vascular disease whose development is influenced by several mediators 1. Among them, the prostanoids large family lipids generated from the metabolism of arachidonic acid by the action of COX includes various types of PGs and thromboxane. Thromboxane A2 and PGI2 are present in abnormally elevated concentration in atherosclerosis 2-3. To exert its effects TXA2 and its precursor PGH2 act at a specific receptor termed TP receptor 4. As a result, TXA2 synthase inhibitors and TP antagonists have been developed to reduce and to prevent TXA2 production and actions, respectively. The present study was undertaken in order to investigate whether BM-573, an original sulfonylurea derivate synthesized in our lab 5, and aspirin would be effective in preventing the progression of atherosclerosis in an apo E deficient mouse model. [less ▲]

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See detailLa maîtrise des strongles gastro-intestinaux en élevage laitier: des pratiques souvent inappropriées.
Picron, Pascale ULg; Turlot, Amélie; Froidmont, Eric et al

Poster (2009, December)

Dans le contexte actuel de crise, le secteur laitier est en difficulté. Il devient alors essentiel de maîtriser les coûts liés à chaque phase d’élevage tout en optimisant la croissance des jeunes animaux ... [more ▼]

Dans le contexte actuel de crise, le secteur laitier est en difficulté. Il devient alors essentiel de maîtriser les coûts liés à chaque phase d’élevage tout en optimisant la croissance des jeunes animaux. La première mise à l’herbe est, dans ce cadre, une étape importante et sensible. Cependant, la méconnaissance de cet aspect de la part des éleveurs et le recours à des pratiques bien souvent inappropriées engendrent des frais superflus sans garantir de manière systématique l’état sanitaire du cheptel. [less ▲]

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See detailEstimation des effets du gène culard sur les caractères de production laitière au sein du rameau Blanc Bleu Belge de type mixte
Colinet, Frédéric ULg; Gengler, Nicolas ULg

Poster (2009, December)

Le rameau Blanc Bleu Belge de type mixte (BBm) est apprécié pour sa rusticité, sa longévité, une bonne santé ainsi que pour ses bonnes performances de reproduction. Une délétion de 11 paires de base ... [more ▼]

Le rameau Blanc Bleu Belge de type mixte (BBm) est apprécié pour sa rusticité, sa longévité, une bonne santé ainsi que pour ses bonnes performances de reproduction. Une délétion de 11 paires de base (allèle mh) au sein du gène de la myostatine engendre le syndrome d’hypertrophie musculaire (plus connu sous le nom de type culard ; d’ailleurs, cet allèle mh est souvent appelé le gène culard). Bien que cet allèle mh soit très présent au sein du rameau Blanc Bleu Belge de type viandeux, seulement 41 et 39 % des animaux BBm sont respectivement mh/mh et mh/+. Etant donné l’importance des effets du gène culard sur la conformation viandeuse des animaux et de son rôle potentiel indirect en production laitière, il nous a semblé intéressant de tenir compte de sa présence lors de l’évaluation génétique des animaux BBm. Néanmoins, il n’est pas envisageable et concevable de génotyper tous les individus de la population BBm. Dès lors, il a fallu modifier légèrement le modèle mixte utilisé pour pouvoir y incorporer ce génotype connu pour certains animaux. La méthodologie ici présentée permet l’estimation simultanée des effets polygéniques (plus connus sous le terme « valeur d’élevage », VE) et de l’effet du gène culard. [less ▲]

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See detailImplementing pedagogic strategies between vets and farmers to create synergies in udder health management: Project Mammipack®
Theron, Léonard ULg; Sustronck, Bart; Bertozzi, Carlo et al

Poster (2009, December)

Udder health is usually considered as a health and economic problem for farmers. We now consider that mastitis is the result of many factors related to the environment, the pathogen and the host. What may ... [more ▼]

Udder health is usually considered as a health and economic problem for farmers. We now consider that mastitis is the result of many factors related to the environment, the pathogen and the host. What may have been forgotten in the process is the fact that nowadays, the main interface with mastitis is the farmer, and their knowledge about mastitis is very heterogeneous. This reflexion has led to the creation of a technical and pedagogical pack called “Mammipack” which contains different tools, from all actors of the dairy chain. We included small charts explaining the most important risk factors identified through epidemiology, good dairy practices and its effect on milk flow, milking machine check-up, how-to for mastitis milk sample, a how-to for performance records use for udder health management, a resume on genetic selection of sires and mastitis, charts upon nutrition factors and their main effect on udder physiology during lactation and dry-off, resume on veterinary drugs good management in the farm. Small laminated sheets upon milk sampling for bacteriology and teats evaluation were also joined in order to be use in parlors, sterile sampling tubes were also given in the pack. A mastitis record pad was designed to record the main clinical forms and the treatment chosen. Eventually, the book Udder Health® was added to have a complete modern look on that problem in dairy farms. 25 farmers were selected on a voluntary base by 12 veterinarians, and they answered to questionnaires about their main practices regarding herd structure, mastitis treatment, and southern Belgium main 19 risk factors. They had to answer basic questions concerning udder health on 15 points. They agreed to keep a record of all next mastitis cases in their farms and take milk samples for bacteriology each time at day 0 and day 21 during 3 months. The main objective is to show to a group of dairy farmers that mastitis could take several different forms from one farm to another, in term of incidence, pathogens and clinical forms. One other purpose is to show the difficulty to have bacteriological cure, even when physical cure has happened. After all, one collateral objective was to create the Mammipack®, designed for farmers and vets to increase their ability to collaborate on mastitis management through most dairy chain actors’ expertise. [less ▲]

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See detailModeling and observation of an upwelling filament off Cape Ghir (NW~Africa) during the CAIBEX campaign
Troupin, Charles ULg; Arístegui, Javier; Barton, Eric Desmond et al

Poster (2009, November 27)

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See detailToxicodynamic of pollutants in poïkilotherm species
Dyc, Christelle ULg; Bouquegneau, Jean-Marie ULg; Debier, Cathy et al

Poster (2009, November 27)

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See detailVariations in sound production in <i>Dascyllus flavicaudus<i>
Kever, Loïc ULg; Lecchini, David; Parmentier, Eric ULg

Poster (2009, November 27)

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See detailCan we use exergy index and the microbenthic loop as indicators of perturbations in Posidonia oceanica (L.) Delile meadows?
Pete, Dorothée ULg; Lenartz, Fabian ULg; Velimirov, Branko et al

Poster (2009, November 27)

Nowadays, many anthropogenic perturbations threaten the Mediterranean Sea. Posidonia oceanica , its endemic phanerogam, is often used as a pollution descriptor. Unfortunately, it does not react very fast ... [more ▼]

Nowadays, many anthropogenic perturbations threaten the Mediterranean Sea. Posidonia oceanica , its endemic phanerogam, is often used as a pollution descriptor. Unfortunately, it does not react very fast because of its low turnover rate (i.e. 1.5y-1). To solve that problem, this project proposes to use the microbenthic loop (meiofauna, bacteria, microphytobenthos and organic matter) of this important coastal ecosystem to detect anthropogenic pollutions earlier, because its components may react more rapidly than the posidonia plant. Every components of the loop are investigated and characterized, in order to determine their reactions to perturbations and use them in the calculation of the exergy index. This index comes from the thermodynamic theory of ecosystems and expresses the distance of an ecosystem, at a given state, from its equilibrium. The higher this index, the closer from its optimum state (climax) the ecosystem is. To calculate it, the biomass of each part of the studied ecosystem, weighted by a factor called β, is needed. This factor is estimated on a genetic basis and given in Jørgensen et al. (2005). The final aim of this project is to show if the exergy index can be used in the Mediterranean Sea as a tool in monitoring strategies, specifically in the sedimentary compartment of P. oceanica meadows. To realise these goals, a reference meadow was chosen near the research station STARESO (STAtion de REcherches Sous-marines et Oceanographiques) in Calvi Bay (Corsica, France). This meadow is studied since the 80’s and its good state of health is proven. Seasonal, spatial (small scale) and bathymetric variations in the microbenthic loop are studied there since 2007, by sediment cores (diameter=4.7cm, length=10cm). Those results are compared for 2008 with the patterns observed in a supposed perturbed site, situated close to a fish farm, in Calvi Bay too. In situ experiments were also led in summer 2009. During three months, a shading experiment and an enrichment of the sediment with sediment coming from under the aquaculture (once a week) were performed. Those experiments aimed to understand reactions of the microbenthic loop to those kinds of perturbations, that are often occurring close to a fish farm. Up to now, that study has led to a better understanding of seasonal and bathymetric patterns in the microbenthic loop of P. oceanica. The most important result obtained is the existence of an important spatial heterogeneity at small scale in that ecosystem. This phenomenon must absolutely be taken into account in every study based on the sediment in P. oceanica meadows. [less ▲]

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See detailMultidisciplinary study of the trophic diversity and functional role of amphipod crustaceans associated to Posidonia oceanica meadows
Michel, Loïc ULg; Lepoint, Gilles ULg; Gobert, Sylvie ULg et al

Poster (2009, November 27)

Posidonia oceanica is a seagrass endemic to the Mediterranean Sea, and is able to form large monospecific areas, called meadows. These meadows are critical features of the Mediterranean coastal zones, and ... [more ▼]

Posidonia oceanica is a seagrass endemic to the Mediterranean Sea, and is able to form large monospecific areas, called meadows. These meadows are critical features of the Mediterranean coastal zones, and are of great ecologic and economic importance. Posidonia oceanica meadows shelter high biomasses and biodiversities of amphipod crustaceans. In other temperate meadows, such as Atlantic Zostera marina meadows, the amphipods play an important part in the functioning of the ecosystem, notably in organic matter transfers from producers to higher level consumers. However, the situation in Posidonia oceanica meadows remains unclear, due to the lack of precise studies, and little is known about the trophic ecology of amphipods. In this context, our research is structured in three main tasks. We chose the Calvi Bay (NW Corsica, France) as a study site, and sampling is undertaken from the STARESO research station (University of Liège, Belgium). First, we study the exact composition of the amphipod community, as well as its temporal variation at diel and seasonal scale. This task is based on in situ collection of samples using three methods: the hand-towed net, litter collection and light traps. Completion of this task will allow us to have accurate and reliable data, taken on our study site, concerning the abundance and specific diversity of amphipods associated with P. oceanica meadows. The second task is a reconstruction of the diet of the studied animals. Indeed, amphipods from P. oceanica meadows are usually regarded as vegetal epiphytes grazers, or generalist detritivores, but few studies focus on the interspecific trophy diversity, or on the importance of alternative food sources. Our approach relies on in situ sampling of amphipods and potential food items. The techniques used combine traditional methods (gut content observation) and use of trophic markers, such as measurements of C and N stable isotope rations and fatty acid composition analysis. Finally, we use in vitro and in situ microcosms experiments to evaluate the impact of amphipod feeding activity on the ecosystem functioning, and more precisely on the dynamics of the epiphyte cover. By quantifying this interaction, our purpose is to put back the results obtained in the first two parts into a wider context, the functioning of the Posidonia oceanica meadow as an ecosystem. Thus, by combining in situ sampling and in vitro experimentation, and by combining traditional and innovating techniques, we hope, at the end of this research, to enhance the knowledge of the trophic diversity and the functional role of amphipod crustaceans associated with Mediterranean Posidonia meadows. [less ▲]

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Peer Reviewed
See detailIMMUNOCAP© ISAC: INTEREST IN ALLERGY DIAGNOSIS
Gadisseur, Romy ULg; Chapelle, Jean-Paul ULg; Cavalier, Etienne ULg

Poster (2009, November 19)

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See detailInfluence of geometry in the case of relative positioning with GNSS
Wautelet, Gilles ULg; Lejeune, Sandrine; Lonchay, Matthieu ULg et al

Poster (2009, November 18)

Relative positioning with GNSS is generally used to achieve precise positions in the frame of critical applications (surveying, photo-control...). On this basis, we have developed a software which allows ... [more ▼]

Relative positioning with GNSS is generally used to achieve precise positions in the frame of critical applications (surveying, photo-control...). On this basis, we have developed a software which allows to compute a positioning error due to the ionosphere only using reference stations belonging to the Belgian Dense Network (BDN). This network consists in 66 GPS (dual-frequency) receivers over the whole Belgium. The drawback of this method is that this computation needs the design matrix which contains coefficients depending on satellite constellation geometry. Therefore, like for absolute positioning, a poor geometry (evaluated by the Dilution of Precision, or DOP) can also lead to large positioning error that cannot be separated from the one due to ionospheric effects, and in particular the small-scale structures. The main goal of this paper is to build a similar index to DOP for relative positioning in our software to be able to separate the ionospheric effects from the geometric ones. The final step is to study the feasability of a service for users of relative positioning using the BDN. The objective is to give in post-processing the positioning accuracy degradation for all BDN baselines and to associate a colour scheme to the different degradation classes created. [less ▲]

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