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See detailGFR estimation equations in HIV-infected patients: one patient, one GFR estimating equation.
Gagneux-Brunon, A; DELANAYE, Pierre ULiege; Mariat, C et al

Poster (2013)

Detailed reference viewed: 6 (0 ULiège)
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See detailDeterminants of sclerostin concentration in hemodialysis patients.
DELANAYE, Pierre ULiege; KRZESINSKI, Jean-Marie ULiege; Warling, X et al

Poster (2013)

Detailed reference viewed: 7 (2 ULiège)
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See detailSelf-coverage of Leidenfrost droplets
Maquet, Laurent ULiege; Colinet, pierre; Moreau, Florian ULiege et al

Poster (2013)

Detailed reference viewed: 59 (13 ULiège)
See detailIdentification of a putative quantitative trait nucleotide (QTN) for host response to Porcine Respiratory and Reproductive Syndrome (PRRS) virus infection.
Koltes, James E; Fritz-Waters, Eric; Choi, Igseo et al

Poster (2013)

Detailed reference viewed: 15 (1 ULiège)
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See detailLa responsabilité des constructeurs
Kohl, Benoît ULiege

Poster (2013)

Detailed reference viewed: 41 (5 ULiège)
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See detailNanomedicines and micromedicines for vectorised radiotherapy of Hepatocellular Carcinoma
Verger, Elise ULiege; Belloche, Camille; Cikankowitz, Annabelle et al

Poster (2013)

Detailed reference viewed: 34 (4 ULiège)
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See detailNanomédecines et micromédecines pour la radiothérapie vectorisée appliquée au traitement du Carcinome Hepato-Cellulaire
Verger, Elise ULiege; Lacoeuille, Franck; Couturier, Olivier et al

Poster (2013)

Detailed reference viewed: 24 (3 ULiège)
Peer Reviewed
See detailInduction of resistance in wheat against powdery mildew by bacterial cyclic lipopeptides
Khong, N.G.; Randoux, B.; Deravel, J. et al

Poster (2013)

Detailed reference viewed: 17 (2 ULiège)
Peer Reviewed
See detailBiosurfactant production by Bacillus sp using sustainable medium and renewable applications of biomass and biosurfactant produced.
Coutte, F.; Etchegaray, A.; Bechet, M. et al

Poster (2013)

Detailed reference viewed: 19 (1 ULiège)
See detailNon Ribosomal Peptides: A monomeric puzzle
Dufresne, Yoann; Leclère, Valérie; Jacques, Philippe ULiege et al

Poster (2013)

Detailed reference viewed: 13 (0 ULiège)
Peer Reviewed
See detailPotential new biopesticides against mildew in lettuce
Van Hese, N.; Van Bogaert, I.; Boistel, C. et al

Poster (2013)

Detailed reference viewed: 30 (3 ULiège)
See detailSurproduction d’un lipopeptide antifongique par Bacillus subtilis à basses températures.
Guy, J.; Coucheney, F.; Chihib, N.E. et al

Poster (2013)

Detailed reference viewed: 22 (1 ULiège)
Peer Reviewed
See detailREALCAT: Advanced high throughput bio(chemical)technologies platform for biorefineries hybrid catalysts design
Dhulster, P.; Jacques, Philippe ULiege; Froidevaux, R. et al

Poster (2013)

Detailed reference viewed: 20 (1 ULiège)
See detailNRPStoolbox : une boîte à outils bioinformatiques dédiée aux NRPs
Pupin, M.; Smail-Tabbone, M.; Jacques, Philippe ULiege et al

Poster (2013)

Detailed reference viewed: 18 (1 ULiège)
See detailExpression des promoteurs des opérons «plipastatine/fengycine» chez Bacillus subtilis.
Hussein, W.; Gancel, F.; Bechet, M. et al

Poster (2013)

Detailed reference viewed: 23 (3 ULiège)
Peer Reviewed
See detailNRPS toolbox : a bioinformatics platform for identifying new non-ribosomal peptides
Pupin, M.; Smail-Tabbone, M.; Caradec, T. et al

Poster (2013)

Detailed reference viewed: 24 (1 ULiège)
Peer Reviewed
See detailGenetic engineering of Bacillus subtilis assisted by computational modelling to overproducing lipopeptide biosurfactants.
Coutte, F.; John, M.; Bechet, M. et al

Poster (2013)

Detailed reference viewed: 18 (1 ULiège)
See detailBiologie synthétique pour la surproduction de lipopeptides chez Bacillus subtilis.
Coutte, F.; John, M.; Bechet, M. et al

Poster (2013)

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See detailLow Sickle Cell Disease Mortality In Belgium and Benefit From Hydroxyurea Therapy
Lê, Phu-Quoc; Dedeken, Laurence; Gulbis, Beatrice et al

Poster (2013)

In Western countries, mortality among patients with sickle cell disease (SCD) has decreased in the last decades by means of neonatal screening (NS), infectious prophylaxis and care improvements. The major ... [more ▼]

In Western countries, mortality among patients with sickle cell disease (SCD) has decreased in the last decades by means of neonatal screening (NS), infectious prophylaxis and care improvements. The major causes of death in children include acute chest syndrome, sepsis, splenic sequestration, stroke, aplastic crisis while in adults end-stage organ failure contributes also to premature death. Hydroxyurea (HU) and stem cell transplantation (SCT) are used in Belgium for more than 20 years but their possible influences on survival have not been yet analyzed. The Belgian SCD Registry was created in 2008 including patients of 8 centres. All available data in 2008 were retrospectively encoded in the database. After 2008 and until 2012, all data were recorded prospectively for already registered patients as well as newly diagnosed subjects. Data were registered from NS or from diagnosis (first contact) until last follow up (FU) visit, SCT or death. Data included diagnosis, demography and outcome data. After SCT, only vital status and cause of death were recorded. Up to date, data from 470 pts are recorded (224 males), 412 are HbSS, 14 HbSβ0, 7 HbSβ+ and 37 HbSC. The median age at diagnosis and at last FU was respectively 0.7 year (y) and 9.9 y. The FU for the whole cohort was 3810 patient-years (PY) and with 136 patients aged over 18y, their FU during adulthood accounted for 520 PY. Thirteen patients died (2.8%). The mortality per 100-PY was 0.34 and the median age at death was 14.5 y (range, 1.5-23.7 y). All deaths occurred in HbSS patients, 5 after SCT and 8 due to an acute event. Complete data set is missing for 3 of the 8 patients. For the 5 well documented SCD related deaths, causes were: hemorrhagic stroke (2), sepsis due to S. pneumoniae (1), aplastic crisis (1) and infection during stay in homeland (1). At last FU, 91 patients were transplanted, 182 were on HU, 7 on HU + chronic transfusion (CT), 19 on CT (4 after HU treatment). The remaining 171 patients never had disease modifying therapy (DMT). Compared with the latter, mortality rate for those on HU was significantly reduced (0.1 vs 0.5/100-PY) while patients on HU have longer FU and are older at last FU (Table 1). Among 91 patients transplanted at a median age 6.9 y, 5 died: 3 from acute transplant related toxicity, 1 from secondary acute myeloblastic leukemia after cGVHD, and 1 is unexplained more than 7 years post SCT. The data issued from the most recent NS cohorts report a low death rate during childhood ranging from 0.13 to 0.52. Even if our Belgian cohort is not exclusively issued from neonatal diagnosis, the observed death rate is low (0.34/100-PY). Several methodological biases are present in this partially retrospective study (incomplete or unavailable data, lost of FU, no information if death occurred before the first contact in a center, …). Nevertheless our low mortality is not underestimated since 1) most patients were followed since infancy and during a long period (3810 PY); 2) the FU during adulthood (period of increased mortality) accounted for 520 PY; 3) our cohort represents a very large part of the Belgian SCD population since a national inquiry performed in 2007 estimated the whole SCD population to 500. The effect of HU on mortality has been reported in adults and more recently in children. Despite longer FU and older age at last FU, our data confirms those previously results. With only one case, death by infection is rare while SCT complications contributed to about 40 % of deaths. Even if SCT is the only curative option for SCD, it encompasses a risk of mortality. As life expectancy of SCD patients has been extended which is confirmed by our results (especially for patients on HU), SCT should be reserved for clinically severe cases. Population-based prospective studies evaluating the survival in transplanted and non transplanted patients are needed. [less ▲]

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See detailAmplification par PCR et Maldi-Tof: outils pour la recherche de peptides NRPS bactériens
Chollet, M.; Abderrahmani, A.; Savadogo, A. et al

Poster (2013)

Detailed reference viewed: 17 (3 ULiège)
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See detailThromboses veineuses cérébrales chez l'enfant
Barrea, Christophe ULiege; Vaessen, Sandrine; Leroy, Patricia et al

Poster (2013)

Detailed reference viewed: 21 (6 ULiège)
Peer Reviewed
See detailDevelopment of a non-lethal sampling method to monitor immune response and disease progression in salmonid fish.
Mira Monte, Milena ULiege; Urquhart, Katy; Hoare, Rowena et al

Poster (2013)

Detailed reference viewed: 24 (1 ULiège)
Peer Reviewed
See detailManaging Rhinophyma: an important lesson.
Takhar, Arun; Stephens, Joanna; POIRRIER, Anne-Lise ULiege et al

Poster (2013)

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See detailSuccessful Recording of Visual Evoked Potentials in a 9.4T Static Magnetic Field
Arrubla Martinez, Jorge Andres ULiege; Neuner, Irene; Hahn, David et al

Poster (2013)

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See detailSuccessful Recording of Auditory P300 in a 9.4T Static Magnetic Field
Neuner, Irene; Arrubla Martinez, Jorge Andres ULiege; Hahn, David et al

Poster (2013)

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Peer Reviewed
See detailValidation of the SinoNasal Outcome Test-23 in septorhinoplasty: a pilot study.
Takhar, Arun; Stephens, Joanna; POIRRIER, Anne-Lise ULiege et al

Poster (2013)

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See detailEtude longitudinale des besoins psychosociaux des conjoints de personnes atteintes d'un cancer : hiérarchisation et résolution de problème
Wagener, Aurélie ULiege; Jonius, Bénédicte; DEVOS, Martine ULiege et al

Poster (2012, December 18)

The existence and importance of psychosocial needs experienced by spouses of cancer patients have been demonstrated repeatedly. In order to reduce these needs, our study assesses the efficacy of the ... [more ▼]

The existence and importance of psychosocial needs experienced by spouses of cancer patients have been demonstrated repeatedly. In order to reduce these needs, our study assesses the efficacy of the combination of two psychotherapeutic methods: psychosocial needs' organisation into a hierarchy and problem solving. Our longitudinal and randomized study comprises three assessment times, separated from three weeks, (T0, T1 and T2) and two groups (experimental and control). At T0, both groups realize the hierarchy of needs. Between T0 and T1, only the experimental group practices problem solving. Then, between T1 and T2, the control group practices this method too. Questionnaires administered at each assessment time are: sociodemographic questionnaire, Hospital Anxiety and Depression Scale (HADS), Psychosocial Needs Inventory (PNI), self-efficacy questionnaire (GSES). Between T0 and T1, a general improvement in scores is expected in both groups: it is expected to be higher in the experimental group who completed the problem solving. Between T1 and T2, scores in the control group should improve to join those obtained by theexperimental group at T1. Thirty-seven people participated: experimental group (N=19, male=12, female=7) and control group (N=18, male=11, female=7). The results confirm our initial hypotheses and emphasize the importance of taking care of cancer patients' spouses. [less ▲]

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See detailIncidence du burnout parmi les radiothérapeutes belges
Bragard, Isabelle ULiege; Hansez, Isabelle ULiege; Etienne, Anne-Marie ULiege et al

Poster (2012, December 18)

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See detailQualité de vie des enfants atteints de mucoviscidose et de leurs parents: Quels sont les prédicteurs?
Toucheque, Malorie ULiege; Lemétayer, Fabienne; Missotten, Pierre ULiege et al

Poster (2012, December 17)

Introduction. La mucoviscidose est une maladie génétique grave, limitant la durée de vie du patient et entraînant de nombreuses complications. Les progrès scientifiques et médicaux ont conduit à ... [more ▼]

Introduction. La mucoviscidose est une maladie génétique grave, limitant la durée de vie du patient et entraînant de nombreuses complications. Les progrès scientifiques et médicaux ont conduit à l’augmentation de l’espérance de vie, de sorte que l’âge moyen de survie est d’environ 40 ans. Dans ce contexte, la qualité de vie (QV) est devenue un objectif thérapeutique important pour les patients atteints de mucoviscidose. Cependant, malgré un intérêt croissant pour le QV, celle-ci a été sous-investiguée chez les enfants âgés de 6 à 12 ans. Parallèlement, on observe que les professionnels de la santé ne sont plus seuls à intervenir dans la prise en charge du jeune patient. L’essentiel du traitement ayant lieu à la maison, la responsabilité concernant la gestion de la maladie reposent désormais sur les épaules de la famille. Ainsi, les parents d’enfants atteints de mucoviscidose doivent faire face à une variété de stresseurs pouvant entraîner d’importantes implications pour le bien-être psychosocial du système familial. Ces dernières années, le rôle de la famille dans l’adaptation des enfants atteints d’une maladie chronique a reçu une attention particulière. À l’heure actuelle, on reconnaît l’importance et l’influence de la relation parent-enfant dans de multiples aspects du développement social et émotionnel de l’enfant. Cependant, dans les recherches en pédiatrie, les pères sont sous-représentés. C’est principalement la relation mère-enfant malade qui a été pris en considération en ignorant la relation père-enfant malade. Objectifs. Ce projet de thèse s’oriente autour de trois objectifs : (1) étudier l’impact de la mucoviscidose sur la QV et, de manière plus générale, sur l’ajustement de l’enfant et de ses parents ; (2) comprendre le lien entre l’ajustement des parents et celui de l’enfant et identifier les mécanismes spécifiques par lesquels les parents influent sur la QV de l’enfant ; (3) étudier l’effet du genre. Méthodologie. Chaque triade (enfant, père et mère) devra répondre à un ensemble de questionnaire évaluant l’ajustement émotionnel, cognitif et comportemental ainsi que le fonctionnement familial et la qualité de vie. Afin d'isoler la spécificité de la mucoviscidose, trois groupes seront créés : mucoviscidose – asthme – sain. Le début du recrutement est prévu en septembre 2012. Contribution. Cette recherche se veut intégrative et contribuera à mettre en évidence les facteurs prédicteurs de la résilience et des difficultés d’ajustement chez les enfants souffrant de mucoviscidose et leur parent. Les résultats contribueront à l’avancement des connaissances et nous permettraient d’influer sur les initiatives de prévention. [less ▲]

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See detailEmpathy for pain and Alexithymia : a rTMS study
Lemaire, Morgan ULiege

Poster (2012, December 12)

Empathy is a multi-facet function regulating social life. In this study, we investigated empathy in relation to alexithymia. Alexithymia is considered as a state showing difficulties in identification and ... [more ▼]

Empathy is a multi-facet function regulating social life. In this study, we investigated empathy in relation to alexithymia. Alexithymia is considered as a state showing difficulties in identification and distinction of one’s own emotional life, as well as difficulties in identification/distinction of others emotions. Thus, alexithymia is considered as an empathy trouble. Previous studies demonstrated that alexithymia is characterized by a particular pattern of cerebral activation comprising some important zones of emotional control (i.e., left DLPFC hyperactivation, left ACC hypoactivation). In the present study, we investigated the electrodermal response of participants during an empathy for pain task before and after an inhibiting rTMS on the right DLPFC to facilitate the ACC activation, with the aim to enhance the emotional expression for alexithymic population. Results showed that rTMS on the right DLPFC increase the relaxation of the alexithymic participants facing the stimuli. This can match our assumptions but further research is needed to clarify this situation. [less ▲]

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See detailSections efficaces de production de rayonnement gamma sur Li et F
Debande, Vivien; Chene, Grégoire ULiege; Strivay, David ULiege

Poster (2012, December 11)

Detailed reference viewed: 53 (9 ULiège)
See detailOncogenic human papillomavirus could directly interact with Natural Killer cells
Renoux, Virginie; Bastin, Renaud ULiege; Boniver, Jacques ULiege et al

Poster (2012, December 10)

Detailed reference viewed: 32 (13 ULiège)
See detailCharacterization of chemotherapy-induced cell death in glioblastoma
Coupienne, Isabelle ULiege; Fettweis, Grégory ULiege; Piette, Jacques ULiege

Poster (2012, December 10)

Glioblastoma constitute the most frequent and deadliest type of brain tumors. Their annual incidence is estimated between 5 and 8 cases per 100,000 people in Europe and North America. They are resistant ... [more ▼]

Glioblastoma constitute the most frequent and deadliest type of brain tumors. Their annual incidence is estimated between 5 and 8 cases per 100,000 people in Europe and North America. They are resistant to all current therapies and are associated with a very high rate of recurrence. The associated prognosis is generally very poor and most patients die within a year after diagnosis. Unfortunately, despite extensive research and use of multimodality treatments combining surgical resection, chemotherapy and radiotherapy, survival hasn’t really much improved over the last 20 years. Indeed, these tumors were shown to be characterized by a high radio- and chemo-resistance. Glioblastoma cells exhibit overexpression of the anti-apoptotic Bcl-2 family proteins and downregulation of its pro-apoptotic members, high expression of the IAPs (Inhibitors of Apoptosis Proteins) and constitutive activation of the pro-survival NF-κB pathway. Currently, the most commonly used treatment offering the best prognosis to patients consists in a combination of maximal surgical tumor resection (when feasible) with subsequent radio- and/or chemotherapy. Among the most commonly used chemotherapeutic agents, the alkylating agent temozolomide and the topoisomerase I inhibitor camptothecin occupy a central position. Therefore, in this study, the impact of both temozolomide and irinotecan (a soluble derivative of camptothecin) on glioma cell survival will be investigated. Important progress was made in the comprehension of the molecular mechanisms underlying tumor development and progression however, survival benefits conferred by the use of new drugs and therapeutic strategies are counted in months rather than years. Consequently, there is an urge to rapidly improve the efficiency of the currently used treatments. This research project consists in (i) the study of the mechanisms implicated in glioblastoma cell death induced by two chemotherapeutic agents : temozolomide and irinotecan, (ii) the identification of the mechanisms underlying the resistance of glioblastoma to these treatments, (iii) the use of pharmacological tools to interfere with those resistance strategies to enhance chemotherapy efficiency. Necrosis was, until recently, long thought to be only accidental. However, it was shown to be finely regulated by specific signalling pathways. Programmed necrosis often takes place in cells in which apoptosis cannot be properly activated and serves as a back-up cell death pathway. Previous work from our lab having already demonstrated that glioblastoma are, at least partially, apoptosis-defective, special emphasis is put on the study of necrotic parameters. Results from survival tests performed on several glioblastoma cell lines in the presence of necrotic inhibitors like necrostatin-1 (an inhibitor of the central regulator of the necrotic pathway RIP1) allows to partially overcome temozolomide and irinotecan-induced glioblastoma cell death, highlighting the role played by programmed necrosis in chemotherapy sensitivity. [less ▲]

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See detailOnline monitoring of the interaction of balls and slurry with the Sensomag ®
Köttgen, Axel; Leroy, Sophie ULiege; Bastin, David ULiege et al

Poster (2012, December 10)

Presentation of Optimag Project results. Optimag aims to optimize the ball milling operations through the use of an embarked sensor, called the Sensomag, and developed by Magotteaux to monitor in real ... [more ▼]

Presentation of Optimag Project results. Optimag aims to optimize the ball milling operations through the use of an embarked sensor, called the Sensomag, and developed by Magotteaux to monitor in real time the position of the slurry and the grinding balls. [less ▲]

Detailed reference viewed: 52 (9 ULiège)
See detailRole of γδ T cells in HPV-induced cancer progression
Van hede, Dorien ULiege; Bastin, Renaud; Francis, Floriane et al

Poster (2012, December 10)

Detailed reference viewed: 38 (9 ULiège)
See detailSéminaire des chercheurs Télévie 2013
Cimino, Jonathan ULiege; Sounni, Nor Eddine ULiege; Calligaris, David ULiege et al

Poster (2012, December 10)

Séminaire des chercheurs Télévie 2013

Detailed reference viewed: 100 (30 ULiège)
See detailRole of HDAC5 depletion induced autophagy on cancer cell death
Hendrick, Elodie ULiege; Peixoto, Paul ULiege; Mathéus, Nicolas et al

Poster (2012, December 10)

Introduction: Histone deacetylases (HDAC) is a family of eighteen enzymes which modulates the acetylation level of histones and non-histone proteins to regulate gene expression and chromatin structure ... [more ▼]

Introduction: Histone deacetylases (HDAC) is a family of eighteen enzymes which modulates the acetylation level of histones and non-histone proteins to regulate gene expression and chromatin structure. Broad spectrum inhibitors of these enzymes can inhibit tumor growth both in vitro and in vivo and are currently used in clinic as anti-cancer agents. For many years, we are investigating the specific role of individual HDAC members in cancer biology and we have recently demonstrated that depletion of HDAC5 using siRNA technology triggered cancer cells to both autophagy and apoptosis. The study of autophagy in cancer is a new research field that has recently generated tremendous attention due to the recognition that autophagy can have either pro-survival or pro-death functions depending on its level of activation. In addition, more and more studies indicate that a complex relationship exists between autophagy and apoptosis, and that the interplay between these two processes determines whether a cell will live or die. - Aims: The aim of this study is to further understand the role of autophagy induced by HDAC5 depletion. Current investigations include determining the molecular mechanisms of HDAC5 depletion-mediated autophagy and exploring regulatory relationships between autophagy and apoptosis on cancer cell death in absence of HDAC5. - Methods and results : The set up of the autophagy in absence of HDAC5 occurs trough a non-canonical pathway which depends on the JNK activation. This activation could be induced by an inappropriate ROS production. Indeed, a transcriptomic analysis performed in HDAC5 depleted Hela cells highlighted a deregulation of a set of genes implicated in ROS detoxification. This deregulation has been validated by FACS analysis. - Conclusion: Through this study we determined the molecular mechanism implicated in the autophagy induction after HDAC5 silencing. This phenomenon appears dependent of an accumulation of ROS into the cells that activates JNK and mediate cell death by autophagy and apoptosis. Now, in we hope to determine whether manipulation of autophagy may provide a useful way to increase the efficacy of treatments with HDAC inhibitors, and limit tumor progression. [less ▲]

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See detailAbundance and phenological model of Harmonia axyridis (Coleoptera: Coccinellidae) in field crops
Vandereycken, Axel ULiege; Brostaux, Yves ULiege; Joie, Emilie ULiege et al

Poster (2012, December 07)

The multicolored Asian ladybeetle Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) was introduced into Western Europe in the late 1990s. This exotic and invasive species is known to thrive ... [more ▼]

The multicolored Asian ladybeetle Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) was introduced into Western Europe in the late 1990s. This exotic and invasive species is known to thrive principally in shrubs and arboreal habitats. We focus on a phonological model and on annual abundance in various field crops. The abundance of H. axyridis adults and larvae were evaluated during a three-year period, from 2009 to 2011, in four important agronomical crops (wheat, corn, broad bean and potato) in Belgium. H. axyridis colonizes and reproduces in all four crops studied, with larger densities observed in corn and broad bean. The reproduction of H. axyridis occurs principally in corn and occurred much less in wheat and potato. From 2009 to 2011, abundances of H. axyridis populations were constant except in corn, where the observed densities of all immature stages and adults were higher in 2011 than in 2009. The population dynamics of aphids and H. axyridis were characterized by a symmetric logistic function (S-shape) based on the cumulative population size. [less ▲]

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See detailBiorthogonalization Techniques for Least Squares Temporal Difference Learning
Jung, Tobias ULiege; Ernst, Damien ULiege

Poster (2012, December 07)

We consider Markov reward processes and study OLS-LSTD, a framework for selecting basis functions from a set of candidates to obtain a sparse representation of the value function in the context of least ... [more ▼]

We consider Markov reward processes and study OLS-LSTD, a framework for selecting basis functions from a set of candidates to obtain a sparse representation of the value function in the context of least squares temporal difference learning. To support efficient both updating and downdating operations, OLS-LSTD uses a biorthogonal representation for the selected basis vectors. Empirical comparisons with the recently proposed MP and LARS frameworks for LSTD are made. [less ▲]

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See detailHorizon Partitioning of soil CO2 sources and their Isotopic Composition (13C) in a Pinus Sylvestris
Goffin, Stéphanie ULiege; Parent, Florian; Plain, Caroline et al

Poster (2012, December 07)

The overall aim of this study is to contribute to a better understanding of mechanisms behind soil CO2 efflux using carbon stable isotopes. Given (i) the interest of conducting in situ studies with soil ... [more ▼]

The overall aim of this study is to contribute to a better understanding of mechanisms behind soil CO2 efflux using carbon stable isotopes. Given (i) the interest of conducting in situ studies with soil multilayer analysis and (ii) the benefits of isotopic tool to improve mechanistic understanding, these two approaches are combined. Quantifying the origin and the determinism of 13CO2 and 12CO2 production processes in the different soil layers using the gradient-efflux approach is the main goal of this work. To meet this one, the work includes an experimental setup and a modeling approach. The experimental set up (see also communication of Parent et al., session B008) comprised a combination of different systems, which were installed in a Scot Pine temperate forest at the Hartheim site (Southwestern Germany). Measurements include (i) half hourly vertical profiles of soil CO2 concentration (using soil CO2 probes), soil water content and temperature; (ii) half hourly soil surface CO2 effluxes (automatic chambers); (iii) half hourly isotopic composition of surface CO2 efflux and soil CO2 concentration profile and (iv) estimation of soil diffusivity through laboratory measurements conducted on soil samples taken at several depths. Using the data collected in the experimental part, we developed and used a diffusive transport model to simulate CO2 (13CO2 and 12CO2) flows inside and out of the soil based on Fick’s law. Given the horizontal homogeneity of soil physical parameters in Hartheim, we treated the soil as a structure consisting of distinctive layers of 5 cm thick and expressed the fick’s first law in a discrete formalism. The diffusion coefficient used in each layer was derived from (i) horizon specific relationships, obtained from laboratory measurements, between soil relative diffusivity and its water content and (ii) the soil water content values measured in situ. The concentration profile was obtained from in situ measurements. So, the main model inputs are the profiles of (i) CO2 (13CO2 and 12CO2) concentration, (ii) soil diffusion coefficient and (iii) soil water content. Once the diffusive fluxes deduced at each layer interface, the CO2 (13CO2 and 12CO2) production profile was calculated using the (discretized) mass balance equation in each layer. The results of the Hartheim measurement campaign will be presented. The CO2 source vertical profile and its link with the root and the Carbon organic content distribution will be showed. The dynamic of CO2 sources and their isotopic signature will be linked to climatic variables such soil temperature and soil water content. For example, we will show that the dynamics of CO2 sources was mainly related to temperature while changing of isotopic signature was more correlated to soil moisture. [less ▲]

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See detailShoulder injury prevention in sports using 3D motion capture
Schwartz, Cédric ULiege; HAZEE, Amandine ULiege; Denoël, Vincent ULiege et al

Poster (2012, December 07)

In sports, where regular and intensive training could progressively lead to traumatic situations, accurate measurement of kinematic parameters can help to predict and anticipate injuries. Overhead ... [more ▼]

In sports, where regular and intensive training could progressively lead to traumatic situations, accurate measurement of kinematic parameters can help to predict and anticipate injuries. Overhead throwing athletes may develop an increased stiffness of the shoulder capsule. The resulting diminution of the gleno-humeral range of motion is usually associated with decreased performance and injury risks. This study illustrates the detection of these situations that put the athlete at risk. [less ▲]

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See detailAnticipating Juno Observations of the Magnetosphere of Jupiter
Bunnell; Fowler; Bagenal et al

Poster (2012, December 07)

The Juno spacecraft will arrive at Jupiter in 2016 and will go into polar orbit. Juno will make the first exploration of the polar regions of Jupiter's vast magnetosphere, combining in situ particles and ... [more ▼]

The Juno spacecraft will arrive at Jupiter in 2016 and will go into polar orbit. Juno will make the first exploration of the polar regions of Jupiter's vast magnetosphere, combining in situ particles and fields measurements with remote sensing of auroral emissions in the UV, IR and radio. The primary science period comprises ~30 orbits with 11-day periods with a~1.06Rj perijove, allowing Juno to duck under the hazardous synchrotron radiation belts. Apojove is at ~38Rj. The oblateness of the planet causes the orbit to precess with the major axis moving progressively south at about 1 degree per orbit, eventually bringing the spacecraft into the radiation belts. This orbit allows unprecedented views of the aurora and exploration of the auroral acceleration regions. We present an overview of anticipated Juno observations based on models of the Jovian magnetosphere. On approach to Jupiter and over a capture orbit that extends to ~180Rj on the dawn flank, Juno will traverse the magnetosheath, magnetopause and boundary layer regions of the magnetosphere. Due to the high plasma pressures in the magnetospheric plasmasheet the magnetosphere of Jupiter is known to vary substantially with the changes in the solar wind dynamic pressure. We use Ulysses solar wind data obtained around 5 AU to predict the conditions that Juno will observe over the several months it will spend in these boundary regions. [less ▲]

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See detailBreeding sites of main Bluetongue virus vectors in Belgian cowshed
Zimmer, Jean-Yves ULiege; Saegerman, Claude ULiege; Losson, Bertrand ULiege et al

Poster (2012, December 07)

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See detailUsing a 2D Model of the Io Plasma Torus to Investigate the Effects of Density Variations on the Morphology and Intensity of the Io Footprint
Payan, Alexia; Rajendar, Ashok; Paty, Carol et al

Poster (2012, December 06)

Io is the primary source of plasma in the Jovian magnetosphere, continuously releasing approximately 1 ton/s of SO2 from volcanic eruptions. The interaction of Io with Jupiter’s magnetosphere is strongly ... [more ▼]

Io is the primary source of plasma in the Jovian magnetosphere, continuously releasing approximately 1 ton/s of SO2 from volcanic eruptions. The interaction of Io with Jupiter’s magnetosphere is strongly influenced by the density structure of the resulting plasma torus and the position of Io relative to the center of the torus [Bonfond et al. 2008]. This unusual interaction produces a complex auroral feature on Jupiter’s ionosphere known as the Io footprint. Hubble Space Telescope (HST) observations of Jupiter’s far-UV aurora during spring 2007 showed an increased number of isolated auroral blobs along with a continuous expansion of Jupiter’s main auroral oval over a few months. These blobs were associated with several large injections of hot plasma between 9 and 27 Jovian radii. These events coincided with a large volcanic eruption of the Tvashtar Paterae on Io, as observed by the New Horizons spacecraft [Spencer et al., 2007]. This, in turn, may have resulted in a significant increase in the plasma torus density. Besides, on June 7th, 2007, the Io footprint momentarily became so faint that it disappeared under a diffuse patch of emission remaining from an injection blob [Bonfond et al., 2012]. The goal of the present study is to examine the relationship between the increased density of the plasma torus and the dimming of the Io footprint. We implement a 2D model of the Io plasma torus that treats the variable-density torus as being composed of discrete layers of uniform density. As the co-rotating plasma in the plasma torus impinges on Io, Alfvén waves are launched at a pushback angle obtained from Gurnett and Goertz [1981]. The waves propagate inside the plasma torus through reflection and refraction at density discontinuities where they lose some of their initial energy. Using the above model, we can track the Alfvén wave fronts in the plasma torus and determine the longitude at which they exit the torus along with the corresponding remaining energy. Since Alfvén waves are capable of accelerating charged particles along magnetic field lines, we assume that the discrete Io footprint features are created at these longitudes, and that the intensity of each of these features is positively correlated to the energy transported by the wave front as it exits the plasma torus. Therefore, the model allows us to investigate both the effects of density changes and of Io’s position in the plasma torus on the intensity and the morphology of the Io footprint. In this context, the model enables us to determine the density increase in the plasma torus required to explain the apparent disappearance of Io footprint given its position at that time. [less ▲]

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See detailLikely Detection of UV Auroral Emission from the Magnetic Footprint of Callisto
Clarke, John; Bhattacharyya, Dolon; Montgomery, Jordan et al

Poster (2012, December 06)

A large number of UV images of Jupiter's aurora were obtained in 2007/2008 with the Hubble Space Telescope (HST) ACS/SBC camera. The initial results on variations with the solar wind conditions have been ... [more ▼]

A large number of UV images of Jupiter's aurora were obtained in 2007/2008 with the Hubble Space Telescope (HST) ACS/SBC camera. The initial results on variations with the solar wind conditions have been published elsewhere, but the large database permits other studies to be performed. In particular, while auroral emissions have been detected from the magnetic footprints of Io, Europa, and Ganymede in Jupiter's atmosphere, the footprint of Callisto has been located too close to the main auroral oval to be detected. We have thus analyzed images of the ultraviolet auroral emissions of Jupiter taken using the F115LP filter on the HST/ACS instrument. Using a unique co-addition method, we have identified a strong candidate for the footprint of Callisto on May 24, 2007. We tested this finding by applying the same co-addition method to a nearly identical auroral configuration on May 30, 2007 when Callisto was well removed in its orbit. Comparing the two co-added images, we can clearly see the presence of Callisto’s footprint on the 24th and its absence on the 30th. The method relies as well on the motion of Callisto's footprint remaining under the satellite, while most of the auroral emissions rotate with the planet. The images and analysis method will be presented in this presentation. [less ▲]

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See detailAnomalous OI-989 Å intensity profile: solving an old mystery.
Hubert, Benoît ULiege; Gérard, Jean-Claude ULiege; Shematovich, Valery I. et al

Poster (2012, December 06)

Sounding rocket measurements conducted in 1988 under high solar activity conditions had revealed that the intensity of the thermospheric OI emission at 989 Å presents an anomalous vertical profile ... [more ▼]

Sounding rocket measurements conducted in 1988 under high solar activity conditions had revealed that the intensity of the thermospheric OI emission at 989 Å presents an anomalous vertical profile. Observation presents an intensity much higher than what can be expected compared with theoretical results including the photochemical sources of excited oxygen and the radiative transfer of the photons of the OI-989 sextuplet especially above the exobase. Attempts were conducted to clarify the discrepancy by including the non-thermal O(3P) population that appears around the exobase and higher, and that can scatter Doppler-shifted photons of the line profile farther from the rest wavelength. All attempts based on detail modeling of the photochemical processes and radiative transfer revealed unable to account for the discrepancy. Recently the FUV and EUV solar flux has been obtained at very high spectral resolution with the SOHO-SUMER instrument, revealing a significant solar oxygen emission at 989 Å, i.e. a source of photons that had never been accounted for before. In this study, we compute the radiative transfer of the OI-989 Å multiplet including the photochemical sources of excited oxygen, the scattering of incident solar photons and the effect of non-thermal atoms. We find a good agreement with the previous sounding rocket observation, solving the old mystery. We also compare the model simulations with the observations of the STP-78 satellite to better determine the relative importance of the various parameters at work in the radiative transfer of the OI-989 Å multiplet. [less ▲]

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See detailCatalytic purification of biogas
Claude, Vincent ULiege; Lambert, Stéphanie ULiege

Poster (2012, December 05)

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See detailBiological network inference with tree-based methods
Schrynemackers, Marie ULiege

Poster (2012, December)

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See detailDevelopment of Highly Active doped Titania Photocatalysts by Aqueous Sol-Gel Processing
Malengreaux, Charline ULiege; Douven, Sigrid ULiege; Poelman, Dirk et al

Poster (2012, December)

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See detailL'intelligence émotionnelle et l'anxiété chez l'enfant: Quel liens?
Stassart, Céline ULiege; Etienne, Anne-Marie ULiege

Poster (2012, December)

Introduction: The concept of emotional intelligence (EI) is characterized by an individual difference to feel, identify, understand, regulate and use their own emotions and those of others. Several ... [more ▼]

Introduction: The concept of emotional intelligence (EI) is characterized by an individual difference to feel, identify, understand, regulate and use their own emotions and those of others. Several studies show a negative association between EI and various fields such as depression and anxiety. At various times, EI has been described as a protective factor against the development of certain disorders or dysfunctions. However, these studies have often been conducted with an adult population and fewer children. But a child is not a miniature adult, there may be differences between child emotional life and that of an adult. Objectives: This study aims to examine the internal consistency of the short version of the scale and French IE in children. Then, the association between EI and trait anxiety is studied, and the share of explanatory IE in the presence of trait anxiety in children, taking into account the effect of gender. Methods: A sample of 198 Belgian children aged between 9 and 13 years old completed the Trait Emotional Intelligence Questionnaire - Short Form Children (TEIQue - CSF) and the State Trait Anxiety Index for Children (STAIC). Results: We observe a good internal consistency of the French version of TEIQue - CSF (α = .83) and a negative correlation between EI and STAIC (r = - .43). The regression analyzes show that EI significantly explains 18% of the variance STAIC. No gender effect was observed. Discussion: As expected, this study demonstrates a negative association between emotional intelligence of the child and the presence of anxiety symptoms, as well as the lack of gender effect in the scores of EI. We also note that the scores TEIQue - CSF significantly predict the presence of anxiety symptoms in boys as well as girls. This is consistent with other studies in a population of adults or adolescents. [less ▲]

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See detailInsulin clearance during hyper-insulinemia euglycemia therapy
Penning, Sophie ULiege; MASSION, Paul ULiege; Pretty, Christopher ULiege et al

Poster (2012, December)

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See detailModel-based glycemic control in critical care
Pretty, Christopher ULiege; Penning, Sophie ULiege; Le Compte, Aaron J. et al

Poster (2012, December)

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See detailLa diversité bactérienne et son évolution pendant la conservation de viandes bovines fraîches de différentes origines conditionnées sous vide
Didimo Imazaki, Pedro Henrique ULiege; Tahiri, Assia ULiege; Taminiau, Bernard ULiege et al

Poster (2012, December)

Le but de cette étude à été d'évaluer la diversité bactérienne et son évolution pendant la conservation de viandes bovine fraîches sous vide, en fonction de leur origine et du respect ou non d’une ... [more ▼]

Le but de cette étude à été d'évaluer la diversité bactérienne et son évolution pendant la conservation de viandes bovine fraîches sous vide, en fonction de leur origine et du respect ou non d’une température proche du point de congélation. Les dénombrements réalisés ont mis en évidence que les viandes d’origines britannique et belge testées présentent un écosystème microbien différent. Les analyses par approche métagénomique permettront d’éclaircir ces différences, surtout en ce qui concerne la présence de bactéries pouvant jouer un rôle "bioprotecteur" permettant d’améliorer la conservabilité des viandes. [less ▲]

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See detailAllelopathic potential of Tunisian barley against weeds
Bouhaouel, Imen ULiege; Gfeller, Aurélie; Fauconnier, Marie-Laure ULiege et al

Poster (2012, December)

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See detailGenetic parameters for individual weights at birth, weaning and 60 days of stress negative Piétrain pigs in the tropics: the case of Vietnam
Do Duc, Luc ULiege; Michaux, Charles ULiege; Dang Vu, Binh et al

Poster (2012, November 28)

Data recorded between 2008 and 2012 from Dong Hiep pig farm, Vietnam, was used to stimate genetic parameters for weights at birth (WB), weaning (WW) and 60 days (W60) of stress negative Piétrain pigs ... [more ▼]

Data recorded between 2008 and 2012 from Dong Hiep pig farm, Vietnam, was used to stimate genetic parameters for weights at birth (WB), weaning (WW) and 60 days (W60) of stress negative Piétrain pigs using restricted maximum likelihood methodology. WB, WW and W60 were recorded from 1146, 839 and 610 animals respectively. The data were analyzed according to a mixed model including 4 fixed effects, parity, season, sex, and interaction between halothane genotype and country of origin (Belgium and Vietnam) of sows. Additionally, 3 random effects (maternal common environment for litter, direct and maternal additive genetic) for WB and 2 random effects (maternal common environment for litter and direct additive genetic) for WW and W60 were included in the model. Estimates of direct heritability and proportion of the maternal common environmental variance for WB, WW and W60 were 0.20, 0.13; 0.22, 0.21 and 0.19, 0.30 respectively. In addition, the estimate of maternal heritability for WB was 0.14. These genetic parameters suggest that WB, WW and W60 could be improved by selection using both direct and maternal effects. [less ▲]

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See detailWhy bother ?
Nazé, Yaël ULiege; Bouquiaux, Laurence ULiege

Poster (2012, November 27)

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See detailA study of Electra posidoniae Gautier (Cheleistomata, Anasca), a bryozoan strictly found as epiphyte of the seagrass Posidonia oceanica (L.) Delile.
Lepoint, Gilles ULiege; Mouchette, Olivier; Pelaprat, Corinne et al

Poster (2012, November 26)

Species living as epiphytes of marine macrophytes have often important role in ecosystem functioning, such as food web suppliers. Some animal or algae species may be considered as really specialised in ... [more ▼]

Species living as epiphytes of marine macrophytes have often important role in ecosystem functioning, such as food web suppliers. Some animal or algae species may be considered as really specialised in the colonization of plant substrate and often dominates epiphytic community, particularly, on long life-span seagrass and macroalgae species. Because epiphytic compartment dysfunction is often implied in seagrass human-induced declining, it is important to understand dynamics and life traits of its specific component in pristine area. In our study, colonization dynamics, biomass seasonality, diet composition of Electra posidoniae, an epiphytic bryozoa, strictly found on the leaves of the seagrass Posidonia oceanica and dominating the leaf epifauna, were assessed monthly at 10 metre depth in the Revellata Bay (Corsica, Mediterranean sea). Aiming to delineate their trophic role in the ecosystem, we have performed bulk stable isotopes measurements and gut content analysis. [less ▲]

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See detailZnO/PVA Macroscopic Fibers Bearing Anisotropic Photonic Properties
Kinadjian, Natacha ULiege; Achard, Marie-France; Julian-Lopez, Beatriz et al

Poster (2012, November 25)

Composite PVA/ZnO-nanorods fibers, synthesized through co-axial flux extrusion exhibit higher anisotropic photonic properties, both in absorption and emission, as a result of the collective alignment of ... [more ▼]

Composite PVA/ZnO-nanorods fibers, synthesized through co-axial flux extrusion exhibit higher anisotropic photonic properties, both in absorption and emission, as a result of the collective alignment of the ZnO nanorods along the main axis of the PVA fiber. This photonic anisotropy is triggered by a synergistic interaction between the PVA matrix, stretched above the glass transition temperature (Tg), and cooled down under strain. Compared with non-elongated fibers that present an isotropic emission, composite fibers previously submitted to a tensile stress absorb selectively UV emission when the polarized laser beam is parallel to the main axis of the fiber. In addition, their photolumincescence is also anisotropic, with a waveguide behavior along the main axis of the fiber. Mechanical properties of these composite fibers are also drastically improved, compared with pure PVA fibers: the longitudinal Young modulus of these fibers is increased from 2 to 6 GPa upon ZnO addition, a value similar to those already observed for composite fibers, prepared either with carbon nanotubes, or V2O5 macroscopic fibers. [less ▲]

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See detailPhotocatalytic TiO2 Macroscopic Fibers Obtained Through Integrative Chemistry
Kinadjian, Natacha ULiege; Le Bechec, Mickael; Pigot, Thierry et al

Poster (2012, November 25)

The photocatalytic properties of titanium dioxide depend not only on its electronic properties, but also on the material size and shape, which can increase interactions between the reactants and catalyst ... [more ▼]

The photocatalytic properties of titanium dioxide depend not only on its electronic properties, but also on the material size and shape, which can increase interactions between the reactants and catalyst. Most studies to date show that reducing the particle size down to the nanoscale increases photocatalytic efficiency, as a result of a higher surface to volume ratio and because a larger proportion of the material is actually irradiated by light. We demonstrate that a multiscale shape design, which integrates surface roughness, particle shape, and 1D material processing and orientation, can favor photocatalytic properties in the solidgas regime, especially mineralization (conversion into CO2), when the hierarchical 1D orientation of the material is combined with unidirectional gas flow. Several materials with hierarchical structure were prepared and characterized. They have been tested for the photocatalytic mineralization of gaseous acetone and compared with commercial catalysts. Our study reveals that a suitable combination of multiscale design and optimization of the material orientation and gas flow favors high mineralization. [less ▲]

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See detailUne étude de la vulnérabilité cognitive des parents au premier degré de patients schizophrènes
Wagener, Aurélie ULiege; Duke, Géraldine; Xhenseval, Laure et al

Poster (2012, November 24)

Les patients schizophrènes et leurs parents au premier degré présentent des déficits cognitifs dans différents domaines (mémoire, fonctions exécutives, attentionnelles et langagières) ce qui permet de ... [more ▼]

Les patients schizophrènes et leurs parents au premier degré présentent des déficits cognitifs dans différents domaines (mémoire, fonctions exécutives, attentionnelles et langagières) ce qui permet de considérer ces déficits comme des endophénotypes de la schizophrénie. Les patients schizophrènes souffrent aussi d’un déficit en mémoire autobiographique et d’une instabilité de l’identité : l’objectif de notre étude est de déterminer si ce déficit et cette instabilité sont des endophénotypes de la schizophrénie. Pour ce faire, nous avons évalué des parents au premier degré. Les résultats mettent en évidence des déficits cognitifs chez les parents au premier degré mais, contrairement à ce que nous attendions, nous n’observons pas de déficit de spécifique et d’instabilité de l’identité chez ces parents. [less ▲]

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See detailSTUDY OF THE INTERACTION BETWEEN FLUORESCENT PDMAEMA AND BLOOD CELLS
Lombart, François ULiege; Flebus, Luca ULiege; Vervecken, Jennifer ULiege et al

Poster (2012, November 22)

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See detailPostoperative bleeding and autotransfusion
ERPICUM, Marie ULiege; BLAFFART, Francine ULiege; DEFRAIGNE, Jean ULiege et al

Poster (2012, November 20)

Bleeding in the postoperative period of cardiac surgery is not rare. Mediastinal bleedings could potentially be saved with a cell salvage device. This practice may contribute to decreased allogeneic ... [more ▼]

Bleeding in the postoperative period of cardiac surgery is not rare. Mediastinal bleedings could potentially be saved with a cell salvage device. This practice may contribute to decreased allogeneic transfusion. This study explores the effectiveness of a chest drainage system combined with a cell salvage option during the postoperative period of cardiac surgery in patients at high risk of bleeding [less ▲]

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See detailMultimodality blood conservation strategy in cardiac surgery with cardiopulmonary bypass: the CHU of Liege experience
ERPICUM, Marie ULiege; BLAFFART, Francine ULiege; DEFRAIGNE, Jean ULiege et al

Poster (2012, November 20)

This study presents the transfusion rates of cardiac surgery patients and describes the in-house strategy of blood conservation applied in a single centre

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See detailContribution to genetic methods of mapping using non-parametric statistical
Abo Al Chamlat, Sinan; Farnir, Frédéric

Poster (2012, November 19)

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See detailAttachement romantique, homophobie intériorisée et soutien social: comparaison entre un groupe italien et un groupe belge.
Messina, Roberta; Scali, Thérèse ULiege; D'Amore, Salvatore ULiege

Poster (2012, November 17)

This poster aims to study the same-sex relationships in two radically different socio-legal contexts (Belgium and Italy). In particular, it highlights the links between the romantic attachment style, the ... [more ▼]

This poster aims to study the same-sex relationships in two radically different socio-legal contexts (Belgium and Italy). In particular, it highlights the links between the romantic attachment style, the internalized homophobia, the social support and the desire and intent of parenthood. The sample is composed by 120 young homosexual people (60 Belgian and 60 Italian), each sub-group is stratified into 2 equal groups according to gender (30 men and 30 women) and to the relational status (30 singles and 30 in a current relationship). Some significant correlations and differences between these groups have been demonstrated, allowing a better understanding of the way to live a relationship and the desire of parenthood among homosexual people. [less ▲]

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See detailSymptoms associated with lumbar instability in athletes with low back pain
GROSDENT, Stéphanie ULiege; Demoulin, Christophe ULiege; Tomasella, Marco ULiege et al

Poster (2012, November 17)

Introduction. Low back pain (LBP) is common among athletes and can be challenging for athletic trainers and therapists. Unfortunately, little is known about symptoms associated with functional lumbar ... [more ▼]

Introduction. Low back pain (LBP) is common among athletes and can be challenging for athletic trainers and therapists. Unfortunately, little is known about symptoms associated with functional lumbar segmental instability (FLSI) in athletes with LBP. Purpose. To determine subjective and objective symptoms associated with FLSI in athletes with LBP. Materials and Methods. We included 24 male athletes (12 soccer players and 12 tennis players) with non specific LBP mean (± standard deviation) pain intensity (0-100 Visual Analogue Scale) and disability (0-24 Roland-Disability questionnaire) scores reaching respectively 35 (±20) and 4 (±3). Athletes were submitted to a standardized anamnesis (including subjective identifiers of FLSI) and a clinical assessment conducted by a manual therapist who explored objective identifiers of FLSI. Results. According to the manual therapist, 12 athletes (6 tennis and 6 soccer players) presented a FLSI. The two groups did not differ regarding pain intensity and disability (P>0.05). However, athletes with FLSI appeared significantly younger than non FLSI athletes (P<0.01). Only three subjective identifiers appeared significantly related to FLSI in soccer and tennis players with LBP: “reports frequent episodes of muscle spasms”, “reports feelings of giving way or back giving out” and “Pain increased with sudden, trivial, or mild movements”. Regarding objective identifiers of FLSI, “positive prone instability test”, “aberrant movement during active and passive trunk flexion-extension“ and “poor lumbopelvic control” were significantly related to FLSI in these athletes. Conclusions. In this preliminary study, 50% of the athletes with LBP presented a FLSI. Some subjective and objective symptoms are significantly related to FLSI in soccer and tennis players. Implications. Athletes with LSI should be targeted for retraining to restore normal movement control. [less ▲]

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See detailEVALUATION AND IMPROVEMENT OF CHILD’S SITTING POSITION IN CLASSROOM
Fettweis, Tatiana ULiege; Henrist, Laura; Vanderthommen, Marc ULiege

Poster (2012, November 17)

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See detailSynthesis and physico-chemical characterization of fatty esters
Sainvitu, Pauline ULiege; Nott, Katherine ULiege; Nicks, Francois ULiege et al

Poster (2012, November 16)

Specific antioxidant molecules (e.g. phenolics) help to prevent oxidation reaction of the cell membrane. A fatty chain grafted on these compounds should enhance their capacity to interact with the ... [more ▼]

Specific antioxidant molecules (e.g. phenolics) help to prevent oxidation reaction of the cell membrane. A fatty chain grafted on these compounds should enhance their capacity to interact with the membrane lipids. In our study, three fatty esters comprising an aromatic part were synthesized. They differentiate the aromatic substituent and the number of carbons between the aromatic ring and the ester function. A structure-function relationships study was performed to identify the structural pattern affecting the interfacial properties and the membrane interaction properties. The behavior of their monolayer film at an air-water interface was studied. The interactions with membrane were assessed on living cells and were predicted by a computational approach. In the future, we will investigate the effect of the presence of a sugar unit on these molecules. [less ▲]

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See detailRing-opening polymerization of cyclic phosphoesters
Vanslambrouck, Stéphanie ULiege; Clement, Benoît ULiege; Jérôme, Christine ULiege et al

Poster (2012, November 16)

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See detailYttrium orthoferrite thin films... a great challenge
Stevens, Frédéric ULiege

Poster (2012, November 16)

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See detailIn silico and in vivo combinatorial design of Octarellin VI, an artificial protein modeled on the (B/A)8 fold
Figueroa Yévenes, Maximiliano ULiege; Taralla, Sébastien; Buscetta, Marco et al

Poster (2012, November 16)

One way to gain insight into the sequence-structure-function relationship in proteins is to perform de novo design of artificial proteins. The applications of such a study are varied. For example, in ... [more ▼]

One way to gain insight into the sequence-structure-function relationship in proteins is to perform de novo design of artificial proteins. The applications of such a study are varied. For example, in medicine and industry, it would give us the ability to precisely engineer proteins to perform a specific function under a wider range of conditions. Despite impressive successes in the de novo protein design, designing a folded protein of more than 100 amino acids remains a challenge. In our lab, four generations of Octarellins, de novo polypeptides of more than two hundred amino acids modelled on the (beta/alpha)8 barrel fold, have been built and structurally characterized using biophysical and spectroscopic methods. The last generation of Octarellins was designed following a hierarchical method combining the specificity of rational design and the power of computational design. The resulting artificial protein, named Octarellin VI, was expressed in E. coli and purified from inclusion bodies. The biophysical characterization showed a monomeric protein, with a secondary structure level similar to the computationally designed model and thermostability. However, the poor solubility in bacteria and low stability of the protein at long term make impossible determine its structure to criticize the model. To improve these negative features, we performed a directed evolution process over the Octarellin, following the improvement at solubility level in the bacteria, thanks to the fusion of Octarellin to the fluorescent folding reporter GFP. After 8 cycles of directed evolution by Error Prone PCR technique, we obtained a most soluble protein, with a 92% of sequence identity with the original protein. This soluble variant is under study to characterize its structural features. The combination between in silico design and directed evolution process emerges as a powerful tool for protein engineering, showing be complementaries techniques and the information obtained by the whole process of design and posterior comparison between 3D structure of Octarellin with the computational model will allow to improve the algorithms for protein design. [less ▲]

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