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See detailDevelopment of formulated elicitors to control bioagressors of wheat: which interests?
Le Mire, Géraldine ULg; Deleu, Magali ULg; Ongena, Marc ULg et al

Poster (2014, February 07)

Crop plants are constantly exposed to a wide range of environmental stresses that can cause major productivity loss. Fungicide treatments are the most efficient disease control methods used up to now ... [more ▼]

Crop plants are constantly exposed to a wide range of environmental stresses that can cause major productivity loss. Fungicide treatments are the most efficient disease control methods used up to now. However, the environmental and health issues caused by these chemicals make it urgent to develop safer methods for pathogen control. In the optic of a sustainable agriculture, several biocontrol tools have been developed during the last decades. Elicitors are increasingly subject to research as interesting alternatives to phytosanitary products. Yet, few efficient formulations exist on the market, and no product has been designed specifically to protect wheat crops. This study will thus focus on the the manipulation of host natural defenses through the use of elicitors as a preventive treatment against major wheat diseases such as Septoria tritici, Fusarium graminearum and Fusarium culmorum. [less ▲]

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Peer Reviewed
See detailDevelopment of an ex-vitro system allowing plant-bacteria interactions through VOCs in the context of water stress
Mendaluk, Magdalena ULg; Baudson, Caroline ULg; Delory, Benjamin ULg et al

Poster (2014, February 07)

Water stress is one of the major environmental factors limiting the crop productivity . Plant stress responses are very complex and drought tolerance may be linked to the presence of specific ... [more ▼]

Water stress is one of the major environmental factors limiting the crop productivity . Plant stress responses are very complex and drought tolerance may be linked to the presence of specific microorganisms in the rhizosphere. Indeed, some plant growth promoting bacteria (PGPR) strains have been found to improve plant growth under abiotic stresses. Among the many mechanisms by which those PGPR can support plant growth, the emission of volatile organic compounds (VOCs) and their biological impact are still under study. The aim of this work is to evaluate the interaction between the model grass Brachypodium distachyon (Bd21) and two strains of PGPR. The impact of volatile emission on Bd21 growth was studied using an ex-vitro cocultivation system without physical contact between plant and bacteria during 10 days. This peculiar system was developed to assess bacterial VOCs impacts on plants under realistic growth and stress conditions. In parallel, the response of Bd21 seedlings to water deficit induced by polyethylene glycol 6000 (PEG 6000) was studied to establish contrasted growth conditions regarding water availability [less ▲]

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See detailRobot weed killers - no pain more gain
Krishna Moorthy Parvathi, Sruthi Moorthy ULg; Mercatoris, Benoît ULg; Boigelot, Bernard ULg

Poster (2014, February 07)

Weed destruction plays a significant role in crop production, and its automation has both economic and environmental benefits by minimizing the usage of chemicals in the fields. Our aim is to design a ... [more ▼]

Weed destruction plays a significant role in crop production, and its automation has both economic and environmental benefits by minimizing the usage of chemicals in the fields. Our aim is to design a small low-cost versatile robot allowing the destruction of weeds that lie between the crop rows by navigating in the field autonomously. Major challenges foreseen are: mapping the unknown geometry of the field, high-level planning of efficient and complete coverage of the field, and controlling the low-level operations of the robot. Traditionally, sensors like odometer have been used for localisation of robots but without much success in real-world scenarios. Specialized sensors like cameras will therefore be investigated and the plethora of image recognition algorithms will be explored and fine-tuned to enable Simultaneous Localisation And Mapping (SLAM) even on resource constrained robotic platforms. Vision-based localisation is not always viable because of the varying weather conditions of the environment and to overcome that, intelligent stochastic data fusion and machine learning algorithms will be utilized to combine data from heterogenous sensor. The image sensors for localisation will be re-used to differentiate crop rows from the weeds, which are cut when they grow. Finally, logics and reinforcement learning techniques will be explored, to exploit the generated map of the field and other sensorial information, to efficiently plan and execute weed elimination. [less ▲]

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See detailEfficient computation of genomically-enhanced inbreeding coefficients
Faux, Pierre ULg; Gengler, Nicolas ULg

Poster (2014, February 07)

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See detailAllelopathic potential of sunflower against the great brome
Bouhaouel, Imen ULg; Gfeller, Aurélie; Fauconnier, Marie-Laure ULg et al

Poster (2014, February 06)

Control methods commonly used to suppress the great brome (Bromus diandrus Roth., syn. Bromus rigidus Roth. subsp. gussonii Parl.) in Tunisian cereal crop are essentially chemical, raising both efficacy ... [more ▼]

Control methods commonly used to suppress the great brome (Bromus diandrus Roth., syn. Bromus rigidus Roth. subsp. gussonii Parl.) in Tunisian cereal crop are essentially chemical, raising both efficacy and safety issues. The introduction of allelopathic species into the crop rotation or utilizing allelopathic plants as living/green mulches has been suggested as a cost-effective way to reduce the weed presence. Among these species, the sunflower (Helianthus annuus L.) has shown an allelopathic potential against some troublesome weed species. In this study, we analyzed the biological activities of water extract of different tissues (root, shoot, leaf and flower) of sunflower on the seedling establishment of the great brome. In a second experiment, the allelopathic influence of sunflower residues (leaf or flower) against this weed was also studied under glasshouse conditions at more advanced stages of growth using different concentrations (0, 6, 12 and 18g tissue dry weight / kg of soil). The first experiment showed an effect depending on the parts of the sunflower. Indeed, the roots seem to be the less allelopathic part (22% of root inhibition growth) as compared to the leaves and flowers (82% and 100%, respectively). This potential seems to simultaneously affect the radicle and the coleoptile growth of the great brome. In the second experiment, weed growth was inhibited in a dose-dependent manner, using increasing amounts of sunflower residues. The allelopathic potential of the leaves or flowers reduced both the root or shoot length and biomass accumulation of the weed. These results suggest that the sunflower can be a good previous crop for cereal cultivation by controlling the presence of some weeds, including the great brome. In this perspective, the inhibitory effects of sunflower residues on cultivated cereals in the field need to be assessed. [less ▲]

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See detailPaleoenvironmental record of the Amik Basin (Amuq Plain, Southern Turkey) over the last 4000 years
Hubert, Aurelia ULg; El Ouahabi, Meriam ULg; Lebeau, Hélène ULg et al

Poster (2014, February 04)

Continous human occupation is attested in the Amik Basin since 6000-7000 BC. The low-lying Amuq plain is covered by tell settlements first explored by Robert Braidwood in the 1930s. The Basin also is ... [more ▼]

Continous human occupation is attested in the Amik Basin since 6000-7000 BC. The low-lying Amuq plain is covered by tell settlements first explored by Robert Braidwood in the 1930s. The Basin also is crossed by The Dead Sea Fault (DSF), a major neotectonic structure in the Middle East extending from the Red Sea in the south to Turkey in the north. The study focuses on the sedimentary record of the Amik Lake occupying the central part of the Basin. Our objective is to constrain major paleo-environmental changes in the area over the last 4000 years and assess possible human impact. The lake has been drained and progressively dried up since the mid-50s so that it is not watered during the summer season and constitutes a unique opportunity to collect sediment records. Sediments were collected at 1 cm to 2 cm intervals in a trench and in cores up to a depth of 5 meters in the clay deposits. A diverse array of complementary methods is applied to study the records: magnetic susceptibility, grain size, organic matter and inorganic carbon (L.O.I), XRD mineralogy, XRF geochemistry, carbon geochemistry. The age of the record is constrained combining radionuclide and radiocarbon dating. The record shows two intense phases of soil erosion with enrichments in Chromium and Nickel. The most recent erosion phase might be linked with enhanced development during the Roman and the growth of the Antioch City. The oldest one would occur around 3000 BC. The record also allows reconstructing past lake level variations and discusses the results in comparison with variations of the Dead Sea. [less ▲]

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See detailComplex I Mitochondrial Dysfunction in HDAC5-depleted Cancer Cells Induces Glucose-dependent Metabolic Reprogramming
Hendrick, Elodie ULg; Peixoto, Paul ULg; Polese, Catherine ULg et al

Poster (2014, February 01)

Introduction : Histone deacetylases (HDAC) is a family of eighteen enzymes, which modulates the acetylation level of histones and non-histone proteins to regulate gene expression and chromatin structure ... [more ▼]

Introduction : Histone deacetylases (HDAC) is a family of eighteen enzymes, which modulates the acetylation level of histones and non-histone proteins to regulate gene expression and chromatin structure. Broad-spectrum inhibitors of these enzymes such as SAHA can inhibit tumor growth both in vitro and in vivo and are currently used as anti-cancer agents in clinic. For many years, we are investigating the specific role of individual HDAC members in cancer biology and we have recently demonstrated that specific depletion of HDAC5 using siRNA technology reduced cancer cells proliferation and survival1. Aims : The goal of this study is to further understand the molecular mechanisms of action of HDAC5 in cancer cells. Methods and results : Screening transcriptomic study demonstrated that HDAC5 depletion induces a down-regulation of NDUFB5, a subunit of the complex I of the mitochondrial respiratory chain through modulation of mRNA stability. HDAC5 depletion-induced NDUFB5 downregulation causes a significant increase of ROS production and induces uncoupled mitochondrial respiration. In addition, this HDAC5 depletion-induced mitochondrial dysfunction provokes metabolic adaptation associated with increased importance of glucose. Indeed, interference with glucose supply in HDAC5-depleted cancer cells significantly increases apoptotic cell death suggesting that glucose deprivation might be combined to HDAC5 inhibition as a therapeutic strategy to kill cancer cells. Conclusions : Our study demonstrated for the first time that specific HDAC5 inhibition induces alteration of NDUFB5 gene expression by altering mRNA stability and provides insight into a valuable experimental strategy for manipulation of specific HDAC5 inhibition and glucose metabolism in therapy against cancer. 1.Peixoto, P. et al. HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells. Cell death and differentiation, 2012; 1-14. [less ▲]

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See detailImportance of recent extreme weather variation in Djibouti and need for impact quantification
Nour Ayeh, Moustapha; Mahamoud, Ayan; Saad, Osman et al

Poster (2014, February)

This analysis shows that the current rainfall deficit is exceptional and historically unique. The significant population migration induced by the drought to Djibouti city must be supervised, especially ... [more ▼]

This analysis shows that the current rainfall deficit is exceptional and historically unique. The significant population migration induced by the drought to Djibouti city must be supervised, especially during their spontaneous settling. This presented example confirms that current rainfall shortages and increasing temperature extremes are impactinglocal people who urgently need adaptation and DRR strategies. It is necessary to reduce exposure to hydrological risks of these affected populations, in order that victims of the drought are not carried away by a rainfall excess. [less ▲]

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Peer Reviewed
See detailControl of phytoplankton bloom by winter conditions in a Mediterranean coastal area : results from a long–term study (1979–2011)
Goffart, Anne ULg; Hecq, Jean-Henri ULg; Legendre, Louis

Poster (2014, February)

The occurrence of a late-winter (February-March) phytoplankton bloom is one of the most unifying features of Mediterranean pelagic ecosystems. However, very little is known about the mechanisms that ... [more ▼]

The occurrence of a late-winter (February-March) phytoplankton bloom is one of the most unifying features of Mediterranean pelagic ecosystems. However, very little is known about the mechanisms that regulate the interannual variability of this phytoplankton bloom in coastal areas. In the present study, we show how winter physical forcing and environmental drivers control surface phytoplankton bloom dynamics in terms of the onset of the bloom, its duration, and its intensity through the analysis of a long-term time series (1979-2011) at the oligotrophic PhytoCly station (Bay of Calvi, Corsica, northwestern Mediterranean). We define a winter intensity index (WII) that integrates wind forcing and water temperature, and discuss strong correlations between WII and both surface nutrient fertilization and phytoplankton bloom intensity. Our study is consistent with reports that phytoplankton blooms can develop in homogenous water columns, and it does not fit the conventional idea that phytoplankton are blooming in temperate oceans because of warming/stratification of the surface layer. [less ▲]

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See detailAnthropogenic effects on African Landscapes: Spatial Structure, Typologies, Ecological Impact
Vranken, Isabelle ULg

Poster (2014, February)

The problematique of anthropogenic disturbance on African landscapes is studied within the double framework of DPSIR (Drivers Pressures States Impact Response) and Pattern/Process Paradygm (Landscape ... [more ▼]

The problematique of anthropogenic disturbance on African landscapes is studied within the double framework of DPSIR (Drivers Pressures States Impact Response) and Pattern/Process Paradygm (Landscape Ecology). 20 landscae images from D.R. Congo, Ivory Coast and Benin were studied using indexes of spatial (compositional and configurational) heterogeneity and anthropogenic disturbance in order to highlight the relationship between spatial structure and disturbance intensity. The results show maximal heterogeneity at intermediate anthropogenic disturbances and fasten the triangular relationship between anthropogenic effect, biodiversity and spatial heterogeneity, that had been partially theoretised with the intermidiate disturbance and habitat heterogeneity hypotheses. [less ▲]

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See detailSoil Seed Bank : a poorly know component of forest regeneration
Douh, Chauvelin ULg; Daïnou, Kasso ULg; Fernandez Pierna, Juan-Antonio et al

Poster (2014, February)

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See detailIMPACT OF COVER CROP MANAGEMENT ON CROP PRODUCTION: A FIELD EXPERIMENT IN WALLONIA CONTEXT
Hiel, Marie-Pierre ULg; Bodson, Bernard ULg

Poster (2014, February)

Minimal soil tillage methods, crop rotation, cover crop and continuous plant residue cover are the main pillars of sustainable agriculture. Lower energy consumption, costs and time are some direct ... [more ▼]

Minimal soil tillage methods, crop rotation, cover crop and continuous plant residue cover are the main pillars of sustainable agriculture. Lower energy consumption, costs and time are some direct benefits in favor to the adaptation of this agriculture. This practices aims also directly at protecting the soil from wind and water erosion by covering the soil. Lower disruption of the soil aims at developping the micro- and macro-fauna activity that increases soil fertility and carbon and nitrogen sequestration in soils. Unfortunately, some of the great constraints to the adaptation of conservation agriculture remain weed management, fungal diseases and pest management, that has been shown to be a problem in non-ploughed fields. The aim of our study is to evaluate, on a same field (Wallonia context), contrasted tillage methods for managing the cover crop and the implantation of the main crop. The following measurements were taken: germination rate, root and shoot biomass development, root notation (size and shape), leaf area index and quality of harvested product. Preliminary results indicate that the different tillage methods did not have a significant impact on crop production or development. However changes in germination dynamics were observed, the reduced tillage inducing slower germination. Regarding weeds populations, some difference were observed in weed occurrences. Since a field exp [less ▲]

Detailed reference viewed: 47 (7 ULg)
Peer Reviewed
See detailExploration on structure activity relation of natural, self-assembling cyclic lipodepsipeptides
Geudens, Niels; Feher, Kristina; De Vleeschouwer, Matthias et al

Poster (2014, February)

Detailed reference viewed: 19 (4 ULg)
Peer Reviewed
See detailNew alternatives to chemical pesticides: deciphering the action mechanisms of lipid based plant elicitors via complementary biophysical and biological approaches.
Nasir, Mehmet Nail ULg; Polo Lozano, Damien ULg; Luzuriaga Loaiza, Walter ULg et al

Poster (2014, February)

Nowadays, many health and environmental problems are caused by the use of chemical pesticides. In this context, an increasing demand for alternative products such as biopesticides has been observed. Among ... [more ▼]

Nowadays, many health and environmental problems are caused by the use of chemical pesticides. In this context, an increasing demand for alternative products such as biopesticides has been observed. Among biopesticides, elicitor molecules which are able to trigger immune defense responses in plants are one of the most promising options. Although numerous elicitors have been discovered, the mechanisms involved in the perception, by plants, of only a few molecules have been identified. These elicitors usually interact with proteic receptors but we have recently shown that they may also act on the lipid phase of the plasma membrane. This project first aims to improve our understanding of the molecular mechanisms involved in the recognition of specific lipid based elicitors (LBE). On that basis, the FIELD project will contribute to the design and the development of innovative compounds derived natural LBE. A multi-disciplinary approach, based on chemistry, bio-physics, bio-chemistry, and phytopathology will be followed by a consortium of different research groups from Gembloux Agro-Bio Tech in close collaboration with teams from foreign institutions. [less ▲]

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See detailMicrofluidic on optical fibers: Towards a new kind of fluorescent biosensor
Lismont, Marjorie ULg; Vandewalle, Nicolas ULg; Weyer, Floriane ULg et al

Poster (2014, February)

In recent works, the behavior of droplets moving along vertical treads due to gravity was studied. It appeared that the droplet can be stopped by encountering a horizontal fiber depending on droplet ... [more ▼]

In recent works, the behavior of droplets moving along vertical treads due to gravity was studied. It appeared that the droplet can be stopped by encountering a horizontal fiber depending on droplet volumes and fiber characteristics. On the basis of this behavior and by replacing treads by two crossed optical fibers, it is possible to combine fluidics and optics to develop a new kind of fluorescent sensor. In our work, the intersection between two crossed optical fibers is used as the basic unit of an original optofluidic biosensor. These two optical fibers are used as droplets carriers: one for probe molecules and the other one for target species. The fiber's junction catches the droplets and act as a reaction center. The main advantage of using optical fibers resides in their ability to propagate and collect light to and from the droplet localized at the fiber's crossing. This optical fiber configuration can therefore allow the study of biological interactions using fluorescent labels. This new and versatile detection scheme was validated on a calcium indicator where ions detection is accomplished by using a dye, Oregon green Bapta-2, that has a Ca 2+ recognition group as well as an entity exhibiting fluorescence. A FRET recognition event, between Rh-Con A and FITC-Dextran, was also investigated to detect glucose. Finally, a prototype of a multiplexing device, composed of several juxtaposed fibers' junctions, was developed. [less ▲]

Detailed reference viewed: 101 (21 ULg)
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See detailSTUDY OF ENVIRONMENTAL CONTAMINATION OVER THE HISTORICAL PERIOD: TRACE ELEMENT AND LEAD ISOTOPIC SIGNATURE IN COASTAL SEDIMENTS FROM CAP CORSICA (FRANCE)
Fontaine, François ULg; lefebvre, lucie; Vranken, François et al

Poster (2014, February)

The Mediterranean coasts have been characterised by intense maritime commercial exchanges since Antiquity. Archeological researches reveal that Cape Corsica (France) may have been an ancient Roman harbor ... [more ▼]

The Mediterranean coasts have been characterised by intense maritime commercial exchanges since Antiquity. Archeological researches reveal that Cape Corsica (France) may have been an ancient Roman harbor. The purpose of this study is first to highlight an anthropogenic contamination due to Roman activities using trace element concentration. Second we aim to identify the contamination sources through Pb isotope composition. Radiocarbon ages performed on macroremains in coastal sediments from Cala Francese (cores CF10-II and CF10-III) allow the localisation of the Roman Period in the sedimentary columns. In core CF 10-II, two major shifts of trace element concentration (such as Pb, Cu, Zn, As and Sb) have been measured at 60-80 and 140-160 cm, corresponding respectively to the Industrial Revolution and to the Roman Period. The same tendency of the Pb concentration is observed in core CF10-III. In this core, the Roman Period is localised between 80 and 140 cm. A major shift in Pb isotopic composition is observed in both core at 140 cm in CF10-II and 60 cm in CD10-III, with a decrease of 206Pb/207Pb ratios and 208Pb/206Pb ratios. All the Pb isotopic ratios match with Pb Roman time signatures from Greece and Spain. Such significant changes in trace metal content and in Pb isotopic signature of sediments are consistent with Human perturbations of the environment during the Roman and Industrial periods. The Pb isotopic signatures measured in Cala Francese are in the same range as those located in other sites of Cape Corsica, indicating a regional contamination. [less ▲]

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See detailCan a global dynamic vegetation model be used for both grassland and crop modeling at the local scale?
Minet, Julien ULg; Tychon, Bernard ULg; Jacquemin, Ingrid ULg et al

Poster (2014, February)

We report on the use of a dynamic vegetation model, CARAIB, within two modeling exercises in the framework of MACSUR. CARAIB is a physically-based, mechanistic model that calculates the carbon ... [more ▼]

We report on the use of a dynamic vegetation model, CARAIB, within two modeling exercises in the framework of MACSUR. CARAIB is a physically-based, mechanistic model that calculates the carbon assimilation of the vegetation as a function of the soil and climatic conditions. Within MACSUR, it was used in the model intercomparison exercises for grassland and crop modeling, in the LiveM 2.4 and CropM WP4 tasks, respectively. For grassland modeling, blind model runs at 11 locations were performed for various time ranges (few years). For crop modeling, a sensitivity analysis for building impact response surfaces (IRS) was performed, based on a bench of model runs at different levels of perturbation in the temperature and precipitation input data over 30 years. For grassland modeling, specific management functions accounting for the cutting or grazing of the grass were added to the model, in the framework of the MACSUR intercomparison. Initially developed for modeling the carbon dynamics of the natural vegetation, CARAIB was already adapted for crop modeling but further modifications regarding the management, i.e., yearly-dependent sowing dates, were introduced. For grassland modeling, simulation results will be further intercompared with other modeling groups, but preliminary results showed that the model could cope with the introduction of the grass cutting module. For crop modeling, building the IRS over 30 years permitted to assess the sensitivity of the model to temperature and precipitation changes. So far, the participation of CARAIB in the intercomparison exercises within MACSUR resulted in further improvements of the model by introducing new functionalities. [less ▲]

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See detailBayesian methods for predicting and modelling winter wheat biomass
Mansouri, Majdi ULg; Dumont, Benjamin ULg; Destain, Marie-France ULg

Poster (2014, February)

The objectives of this paper are threefold. The first objective is to propose to use an Improved Particle Filtering (IPF) based on minimizing Kullback-Leibler divergence for crop models' predictions. The ... [more ▼]

The objectives of this paper are threefold. The first objective is to propose to use an Improved Particle Filtering (IPF) based on minimizing Kullback-Leibler divergence for crop models' predictions. The performances of the proposed technique are compared with those of the conventional Particle Filtering (PF) for improving nonlinear crop model predictions. The main novelty of this task is to develop a Bayesian algorithm for nonlinear and non-Gaussian state and parameter estimation with better proposal distribution. The second objective is to investigate the effects of practical challenges on the performances of state estimation algorithms PF and IPF. Such practical challenges include (i) the effect of measurement noise on the estimation performances and (ii) the number of states and parameters to be estimated. The third objective is to use the state estimation techniques PF and IPF for updating prediction of nonlinear crop model in order to predict winter wheat biomass. PF and IPF are applied at a dynamic crop model with the aim to predict a state variable, namely the winter wheat biomass, and to estimate several model parameters. Furthermore, the effect of measurement noise (e.g., different signal-to-noise ratios) on the performances of PF and IPF is investigated. The results of the comparative studies show that the IPF provides a significant improvement over the PF because, unlike the PF which depends on the choice of sampling distribution used to estimate the posterior distribution, the IPF yields an optimum choice of the sampling distribution, which also accounts for the observed data. [less ▲]

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See detailImmunomodulatory effects of Rapamycin in xenogeneic GVHD
Ehx, Grégory ULg

Poster (2014, January 31)

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Several studies have shown that rapamycin (RAPA), an mTOR ... [more ▼]

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Several studies have shown that rapamycin (RAPA), an mTOR inhibitor with immunosuppressive properties, may reduce GVHD severity and mortality, notably by favoring regulatory T cells (Tregs) proliferation in vivo and in vitro. However, very few data have been reported about the global impact of this drug on the immune system in the context of GVHD. The present work investigates the cellular mechanisms by which RAPA delays death from xenogeneic GVHD induced by peripheral blood mononuclear cells infusion in NSG mice. Our results show that RAPA injections significantly delay death from xenogeneic GVHD and reduce disease severity. Flow cytometric analyses highlighted a strong reduction of human cells chimerism in mice together with higher CD4+/CD8+ T cells balance due to a lower proliferation of CD8+ T cells. In addition, the frequencies of naive CD4+ and CD8+ T cells were higher and the CD4+ T cells showed a reduced effector phenotype (CD45RO+CD27-). Tregs were positively affected as RAPA up-regulated their expression of Bcl-2 and Ki67 as well as their STAT5 phosphorylation level, leading to higher Treg frequency in treated mice. Altogether these data demonstrate that RAPA delays xenogeneic GVHD by lowering human chimerism and effector CD4+ frequency as well as promoting Tregs. [less ▲]

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See detailL'oxydation des poudres: un défi pour l'avenir
Blecker, Christophe ULg

Poster (2014, January 27)

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See detailGIGA ANIMAL CARE : Mice & Zebrafish Animal Facility and Transgenesis
Remy, Benoît ULg; Ectors, Fabien ULg; Winandy, Marie ULg et al

Poster (2014, January 27)

In fundamental research, animal models allow to place molecular and cellular observations back into their physiological context. In applied research, these models still remain a mandatory step to evaluate ... [more ▼]

In fundamental research, animal models allow to place molecular and cellular observations back into their physiological context. In applied research, these models still remain a mandatory step to evaluate the efficiency and the toxicity of potential treatments, before going to clinical trials. Mouse and Zebrafish (Danio rerio) are two very interesting models because of a short live cycle and a high prolificacy. They require a limited space. Their genome is well known and shows a high homology with the human. Many tools are available to produce transgenic mice or zebrafishes. Many tests are validated using both these species. [less ▲]

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See detailKisspeptin and neuronal nitric oxide signaling are important in female sexual behavior
Hellier, Vincent ULg; Bakker, Julie

Poster (2014, January 27)

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See detailCryopreservation of embryos : a way to reduce the number of housed animals and the genetic drift.
Remy, Benoît ULg; Ectors, Fabien ULg; Drion, Pierre ULg

Poster (2014, January 27)

The GIGA Mouse facility platform has recently improved its mouse line cryopreservation technique. The method of embryo cryopreservation by rapid cooling also called aseptic vitrification has been selected ... [more ▼]

The GIGA Mouse facility platform has recently improved its mouse line cryopreservation technique. The method of embryo cryopreservation by rapid cooling also called aseptic vitrification has been selected. Vitrification media, key steps and timing have been optimized and validated. After a first partial exposition of the embryos to cryoprotective solutions, they are immersed in a vitrifying mixture of penetrating and non-penetrating cryoprotectants for a short time. The straw containing the embryos is immediately sealed before to be plunged in LN2, resulting in a brutal solidification in which crystallization does not have time to occur. [less ▲]

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See detailDUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase
Amand, Mathieu ULg; Erpicum, Charlotte ULg; BAJOU, Khalid ULg et al

Poster (2014, January 27)

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See detailImmunomodulatory effects of Rapamycin in xenogeneic GVHD
Ehx, Grégory ULg; HANNON, Muriel ULg; DUBOIS, Sophie ULg et al

Poster (2014, January 27)

Detailed reference viewed: 23 (12 ULg)
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See detailGenome-wide association interaction analysis for Alzheimer’s disease.
Gusareva, Elena ULg; Bellenguez, C; Cuyvers, E et al

Poster (2014, January 27)

Detailed reference viewed: 7 (0 ULg)
See detailComplex I Mitochondrial Dysfunction in HDAC5-depleted Cancer Cells Induces Glucose-dependent Metabolic Reprogramming
Hendrick, Elodie ULg; Peixoto, Paul ULg; Matheus, Nicolas ULg et al

Poster (2014, January 27)

Introduction : Histone deacetylases (HDAC) is a family of eighteen enzymes, which modulates the acetylation level of histones and non-histone proteins to regulate gene expression and chromatin structure ... [more ▼]

Introduction : Histone deacetylases (HDAC) is a family of eighteen enzymes, which modulates the acetylation level of histones and non-histone proteins to regulate gene expression and chromatin structure. Broad-spectrum inhibitors of these enzymes such as SAHA can inhibit tumor growth both in vitro and in vivo and are currently used as anti-cancer agents in clinic. For many years, we are investigating the specific role of individual HDAC members in cancer biology and we have recently demonstrated that specific depletion of HDAC5 using siRNA technology reduced cancer cells proliferation and survival1. Aims : The goal of this study is to further understand the molecular mechanisms of action of HDAC5 in cancer cells. Methods and results : Screening transcriptomic study demonstrated that HDAC5 depletion induces a down-regulation of NDUFB5, a subunit of the complex I of the mitochondrial respiratory chain through modulation of mRNA stability. HDAC5 depletion-induced NDUFB5 downregulation causes a significant increase of ROS production and induces uncoupled mitochondrial respiration. In addition, this HDAC5 depletion-induced mitochondrial dysfunction provokes metabolic adaptation associated with increased importance of glucose. Indeed, interference with glucose supply in HDAC5-depleted cancer cells significantly increases apoptotic cell death suggesting that glucose deprivation might be combined to HDAC5 inhibition as a therapeutic strategy to kill cancer cells. Conclusions : Our study demonstrated for the first time that specific HDAC5 inhibition induces alteration of NDUFB5 gene expression by altering mRNA stability and provides insight into a valuable experimental strategy for manipulation of specific HDAC5 inhibition and glucose metabolism in therapy against cancer. 1.Peixoto, P. et al. HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells. Cell death and differentiation, 2012; 1-14. [less ▲]

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See detailScikit-Learn: Machine Learning in the Python ecosystem
Joly, Arnaud ULg; Louppe, Gilles ULg

Poster (2014, January 27)

The scikit-learn project is an increasingly popular machine learning library written in Python. It is designed to be simple and efficient, useful to both experts and non-experts, and reusable in a variety ... [more ▼]

The scikit-learn project is an increasingly popular machine learning library written in Python. It is designed to be simple and efficient, useful to both experts and non-experts, and reusable in a variety of contexts. The primary aim of the project is to provide a compendium of efficient implementations of classic, well-established machine learning algorithms. Among other things, it includes classical supervised and unsupervised learning algorithms, tools for model evaluation and selection, as well as tools for data preprocessing and feature engineering. This presentation will illustrate the use of scikit-learn as a component of the larger scientific Python environment to solve complex data analysis tasks. Examples will include end-to-end workflows based on powerful and popular algorithms in the library. Among others, we will show how to use out-of-core learning with on-the-fly feature extraction to tackle very large natural language processing tasks, how to exploit an IPython cluster for distributed cross-validation, or how to build and use random forests to explore biological data. [less ▲]

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See detailArt et schizophrénie : étude comparative de biographies d’artistes d’art brut et de sujets schizophrènes peintres
Moffarts, Aloïse; Englebert, Jérôme ULg

Poster (2014, January 22)

La psychopathologie phénoménologique explique la schizophrénie en termes de perte de l'évidence naturelle (Blankenburg, 1991/1971) ou de psychopathologie du sens commun (Stanghellini, 2000, 2004, 2007 ... [more ▼]

La psychopathologie phénoménologique explique la schizophrénie en termes de perte de l'évidence naturelle (Blankenburg, 1991/1971) ou de psychopathologie du sens commun (Stanghellini, 2000, 2004, 2007). Concernant les théories consacrées à l'art et la psychopathologie, nous nous penchons sur la théorie de la Gestaltung de Prinzhorn (1984), sur l’hypothèse de l’« l'art révolutionnaire » de Sass (1992 ; Spaniol, 2001) et analysons la classification de Jádi (Hulak, 1990). Enfin, à partir de ces travaux, nous avons établi trois types d'art qui peuvent se retrouver chez des artistes malades mentaux : art brut, art naïf et art de recherche. Notre méthodologie consiste à analyser la biographie de deux artistes peintres de la famille de « l'art brut » (Aloïse Cobraz et Adolf Wölfli) en les comparant aux biographies et analyses de cas de deux patients schizophrènes se considérant comme artistes peintres. Nous avons élaboré un questionnaire semi-structuré pour questionner les artistes sur leur parcours artistique et leur rapport à l’art. Après nos analyses et le croisement avec les théories existantes, nous émettons comme hypothèse que les schizophrènes artistes se distinguent des autres types d’artistes (pathologiques ou non) dans leur rapport à la créativité. Ceci est congruent avec le concept d’« art révolutionnaire » de Sass (1992). La classification de Jádi nous permet de suggérer qu’il n’est pas cohérent de parler d’un art des malades mentaux et que le trouble psychiatrique ne peut donc pas être considéré comme l’essence de l'art brut. Enfin, nous pouvons émettre l’hypothèse que l'art semble conférer aux schizophrènes artistes une forme d'adaptation sociale eu égard au sens commun « perdu ». [less ▲]

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See detailLe Rorschach selon le Système Intégré et le TCI-R : comparaison et intégration
Rentmeister, Daniel; Englebert, Jérôme ULg; Blavier, Adelaïde ULg

Poster (2014, January 22)

Pour cette étude, un double objectif est recherché. Premièrement, nous comparons statistiquement le test de Rorschach selon le Système Intégré de J.E.Exner et le Temperament and Character Inventory – ... [more ▼]

Pour cette étude, un double objectif est recherché. Premièrement, nous comparons statistiquement le test de Rorschach selon le Système Intégré de J.E.Exner et le Temperament and Character Inventory – Revised de R. Cloninger afin de mettre en évidence leurs divergences et convergences. Deuxièmement, à l’aide de cas cliniques, nous discutons de la pertinence de l’intégration des résultats obtenus par ces deux outils en vue d’établir le profil psychologique complet et cohérent d’un individu. Pour la comparaison statistique, notre échantillon de 27 sujets tout-venant (M = 24,37 ans ; SD = 2,75) a d’abord été soumis au test de Rorschach. Directement après, chaque sujet a complété le TCI-R. Une analyse de corrélation (Rho de Pearson) a été calculée entre les indices et un ajustement de Bonferroni a été effectué. Pour l’analyse de cas, 3 sujets cliniques ont été recrutés. Une anamnèse a été réalisée et le test de Rorschach et TCI-R administré. Nos premiers résultats, qui sont à prendre avec prudence au vu du faible nombre de sujet de l’échantillon, sont à nuancer et discuter. À partir de 2016 comparaisons statistiques, nous sélectionnons les résultats les plus pertinents et discutons des différentes corrélations observées. Les analyses de cas nous montrent une concordance au niveau des relations sociales et de l’impulsivité ; et nous montrent que les informations propres à chaque test permettent de compléter le profil du sujet. Enfin, c’est en abordant les deux épistémologies différentes sur lesquelles reposent ces deux tests que nous pouvons expliquer au mieux les différences psychologiques mises en évidence à propos des mêmes individus. Nous concluons en suggérant que cette différence de résultats doit certainement être comprise selon une logique intégrative et souligne la complémentarité existant entre ces deux épreuves. [less ▲]

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See detailLe problème des protocoles longs au test de Rorschach
Dufour, Cristelle; Englebert, Jérôme ULg

Poster (2014, January 22)

Notre étude s’intéresse aux protocoles exceptionnellement longs (supérieurs à 50 réponses) fournis par cinq sujets au test du Rorschach administré et interprété selon la méthode du Système Intégré (Exner ... [more ▼]

Notre étude s’intéresse aux protocoles exceptionnellement longs (supérieurs à 50 réponses) fournis par cinq sujets au test du Rorschach administré et interprété selon la méthode du Système Intégré (Exner, 2003). Afin de mieux comprendre quelle attitude adopter face à ce type de protocole, nous avons effectué une réduction a posteriori du nombre de réponses en nous basant sur les recommandations d’Exner (1988, 1992, 2003). Nous avons ensuite réalisé une étude comparative entre l’interprétation clinique réalisée avec la totalité des réponses et avec seulement les cinq premières réponses par planche. Nous avons également reproduit cette méthodologie de réduction a posteriori du nombre de réponses avec quatre réponses par planche en nous inspirant des nouvelles recommandations du système R-PAS de Meyer et al. (2009). Selon ces propositions, un protocole de test de Rorschach serait valide lorsque le sujet fournit entre 20 et 40 réponses (entre 2 et 4 par planche). L’échantillon est composé de trois sujets tout-venant et deux sujets psychiatriques. Notre analyse a mis en évidence une stabilité de certaines variables (EB, Lambda, EA) mais d’importantes différences dans le profil psychologique des sujets après réduction. Nous avons observé une clarification des difficultés fondamentales chez les sujets psychiatriques et plutôt une neutralisation de ces difficultés pour les sujets tout-venant, avec notamment des stratégies défensives qui apparaissent plus adaptées. Selon les résultats obtenus à partir de notre échantillon, nous pouvons suggérer que la prise en compte de la totalité des réponses ou seulement du protocole partiel induit une différence dans l’interprétation clinique. En conséquence, toute réduction du nombre de réponses devrait se faire avec grande prudence. Notre étude permet de discuter des pratiques actuelles du test de Rorschach, en faisant dialoguer les contraintes inhérentes à la validité du test et les questions de la réduction de la complexité clinique propres à toute entreprise de standardisation. [less ▲]

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See detail“A QUICK HIGH BEFORE IMMERSION INTO THE DEEP BLUE: THE FALL OF ICARUS REVISED.”
Lopez-Rodrigez, Alicia; BRASSEUR, Edmond ULg; GHUYSEN, Alexandre ULg et al

Poster (2014, January 18)

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See detailAN UNUSUAL CERVICALGY.
PIAZZA, Justine ULg; BRASSEUR, Edmond ULg; Ghuysen, Alexandre ULg et al

Poster (2014, January 18)

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See detailDE L’AIR DANS LA VESSIE?
TAMBWE RAMAZANI, Willy ULg; BRASSEUR, Edmond ULg; Johnson, S et al

Poster (2014, January 18)

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See detailDendroecology and Dendroclimatology of a Tasmanian Bog Forest
Balanzategui, Daniel; Copenheaver, Carolyn; Frank, David et al

Poster (2014, January 14)

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See detailDepression and autobiographical memory: which are the characteristics of depressed patients' self-defining memories?
Wagener, Aurélie ULg; Weigend, Alicia; Boulanger, Marie ULg et al

Poster (2014, January 13)

BACKGROUND. Depressed patients suffer from autobiographical memory deficits. Indeed, depressed patients present an overgeneralization and a mood congruence biases. Moreover, they seem to have difficulties ... [more ▼]

BACKGROUND. Depressed patients suffer from autobiographical memory deficits. Indeed, depressed patients present an overgeneralization and a mood congruence biases. Moreover, they seem to have difficulties to recall positive memories. Our aim is to focus on a specific kind of memories called “self-defining memories” (SDM) which are highly pertinent for self-building. Their characteristics (e.g. specificity, meaning making) were assessed and compared to those of healthy subjects. HYPOTHESES. Depressed patients relate less specific and meaning making events than control group. A mood congruence bias is observed. METHOD. 17 depressed patients and 18 healthy subjects fulfilled SDM exercises: subjects were asked to relate six important events that happened in their life. These SDM were assessed on several variables: specificity, impact, meaning making, contain. Moreover, subjects were assessed on depression severity and self-esteem (explicit and implicit). RESULTS. No difference between depressed patients and healthy subjects has been found for specificity. A marginal effect appeared for meaning making: control group seemed to relate more meaning making events than depressed patients. Depressed patients related more negative events than control group: this negative emotional valence was positively correlated with higher depression severity. Depressed subjects presented a lower explicit self-esteem than healthy subjects but no difference has been found for implicit self-esteem. Higher explicit self-esteem was positively correlated with positive emotional valence of SDM. DISCUSSION. Results partially support our hypotheses. Experimental and clinical implications of our results will be discussed. [less ▲]

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See detailSelves Impairment in Bipolar Disorder through Self-Concept Clarity, Self-Defining Memories and Self-Esteem
Wagener, Aurélie ULg; Boulanger, Marie ULg; Van Limbergen, Coralie et al

Poster (2014, January 13)

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See detailFunctional traits and speciation of tropical African species: the case of genus Guibourtia Benn
Tosso, Dji-ndé Félicien ULg; Daïnou, Kasso ULg; Hardy, J. Olivier et al

Poster (2014, January 07)

Nowadays, comparative ecology approach is widely used to understand mechanisms of speciation. In evolutionary biology, few studies take into account the importance of physiological traits as criteria for ... [more ▼]

Nowadays, comparative ecology approach is widely used to understand mechanisms of speciation. In evolutionary biology, few studies take into account the importance of physiological traits as criteria for interspecific differentiation, although such an approach is particularly suited to infer the adaptive capacities of taxa. The genus Guibourtia Benn (Fabaceae / Caesalpinioideae), composed of 13 species in Africa, seems an ideal candidate for this study. As a matter of fact, this model includes not only species of different vegetation ecosystems (forest and savanna) but also morphologically very similar species found in various areas with different climates and soils (sandy, clayloam, limestone, hydromorph). Addressing speciation issues, our study seeks to test the hypothesis that populations of closely related species should be studied in terms of both functional traits and phylogeny. In this research, two questions are asked: (i) what are the phylogenetic differences within the genus Guibourtia? (ii) To what extent phylogeny, functional traits and bioclimatic envelope are linked? The results of the study will help to realize the distribution modeling of different evolutionary units of Guibourtia using a dynamic vegetation model (CARAIB) in order to propose strategies for conservation and sustainable management in the context of Central African forests. [less ▲]

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See detailImatinib improves survival of chronic Graft-versus-host disease by inhibiting TGF-β and PDGF-R in mice
Fransolet, Gilles ULg; Belle, Ludovic ULg; SOMJA, Joan ULg et al

Poster (2014, January)

Introduction: Graft-versus-host disease (GVHD) remains a major complication of allogeneic hematopoietic stem cell transplantation (HSCT). Approximately 15% of the patients develop the sclerodermatous ... [more ▼]

Introduction: Graft-versus-host disease (GVHD) remains a major complication of allogeneic hematopoietic stem cell transplantation (HSCT). Approximately 15% of the patients develop the sclerodermatous cGvHD (scl-cGvHD) form of the disease characterized by multiple organ fibrosis and loss of skin elasticity. A few studies have suggested potential benefits of imatinib, a tyrosine kinase inhibitor, as a treatment of fibrosis in scl-cGVHD due to its ability to inhibit simultaneously the PDGF receptor and TGF-β pathways (via ABL inhibition), which are both involved in fibrosis . Aim: This work investigates the impact of imatinib on fibrosis in the B10.D2 to BALB/cJ scl-cGvHD murine model. Lethally irradiated BALB/cJ recipient mice were injected with 107 bone marrow cells + 7.107 splenocytes from B10.D2 donor mice. Recipients were treated with imatinib 150 mg/kg/day (50 mg/kg in the morning followed by 100 mg/kg in the evening) by oral gavage or the same volume of sterile water. Mice health status was evaluated with a scoring system encompassing five criteria (weight loss, activity, fibrosis, hair loss and mice posture; 0-1-2 points/criteria). Mice were sacrificed at a score of 8/10 according to our local ethical committee. Results: Mice given daily 150 mg/kg imatinib had a better survival than control mice (42 versus 33 days, p = 0,0357). cGvhD scores were suggestively lower in imatinib-treated than in control mice (p ≤ 0,15). Further, histological analyses evidenced reduction in the levels of both PDGF receptor (p = 0,033) and c-Abl (p = 0,185) phosphorylation in imatinib as compared to control mice. Finally, no significant differences were observed in the number or frequency of lymphocyte subsets in the 2 groups of mice. Conclusion: Imatinib slightly decreased fibrosis and significantly improved survival in a severe scl-cGvHD murine model. [less ▲]

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See detailPromotor specific regulation of NF-kappaB mediated transcription by the phosphorylation of p65 on Ser547.
Trussart, Charlotte ULg; Orban, Tanguy ULg; Sabatel, Hélène ULg et al

Poster (2014, January)

NF-kappaB (p50/p65) is an important regulator of gene transcription as it controls the expression of hundred of genes involved in inflammatory and innate responses, proliferation, survival, cancer ... [more ▼]

NF-kappaB (p50/p65) is an important regulator of gene transcription as it controls the expression of hundred of genes involved in inflammatory and innate responses, proliferation, survival, cancer initiation and progression. Several modes of NF-kappaB activation are known among which the classical pathway induced by pro-inflammatory cytokines and a complex atypical pathway induced by DNA damage. Both pathways converge on the IKK activation. The stimulidependent p65 phosphorylation on several serine can control its transcriptional potential either globally or often in a gene specific manner. Lately, we have reported a direct interaction between p65 and ATM and the in vitro phosphorylation of Ser547 by this kinase. A comparative transcriptomic analysis performed in HEK-293 cells expressing either p65WT or p65S547A identified several differentially transcribed genes (IL8, A20, SELE…) after an Etoposide treatment. Substitution of Ser547 to Ala does not affect p65 binding on the kappaB site of the IL8 promoter but it reduces p65 interaction with HDAC1 leading to a higher level of histone H3 acetylated on Lys9 and therefore a higher gene induction. These data indicate that ATM regulates a sub-set of NF-kappaB dependent genes after a genotoxic stress by direct phosphorylation of p65 (1). We are now investigating the impact of the S547A mutation in the context of an inflammatory response. Mefs p65KO expressing recombinant p65WT or p65S547A were treated with TNFalpha. No differences were observed in the kinetic of degradation of IkBa or the nuclear translocation of p65. The level of transcription of a few selected genes is presently under investigation. Contrary to another study, we did not observed any role of ATM in NF-kappaB activation by TNFalpha [less ▲]

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See detailMelanoma AntiGEn D2 (MAGED2) a new partner of the DNA damage response?
Pirlot, Céline ULg; Piette, Jacques ULg; Habraken, Yvette ULg

Poster (2014, January)

MAGED2 belongs to the Melanoma AntiGEn (MAGE) family of proteins. It is ubiquitously expressed and its overexpression in many cancers could make it a potential biomarker of tumor development and ... [more ▼]

MAGED2 belongs to the Melanoma AntiGEn (MAGE) family of proteins. It is ubiquitously expressed and its overexpression in many cancers could make it a potential biomarker of tumor development and metastasis formation. Actually, the only known function of this protein is its involvement in the p53 pathways. Indeed, MAGED2 could be a negative regulator of p53 and it increases apoptosis induced by TRAIL in a p53 dependent manner. Moreover, a phosphoproteomic experiment has shown that this protein is likely phosphorylated by ATM, ATR or DNA-PK after exposition to ionizing irradiation. These three kinases are implicated in the DNA damage response (DDR). Our lab showed by yeast two hybrids an interaction between MAGED2 and ATM. Thus, the aims of the project are to confirm and to find the function of this interaction in a DDR context. Current avenues of investigations include determining the impact of MAGED2 depletion and overexpression in the p53, NF-kappaB and cell cycle regulation following double strand break induced by etoposide treatment. Though this study we plan to confirm a new partner of ATM in the DDR pathway, which could be targeted to limit cancer progression and improve the chemotherapy relying on DNA damaging compounds. [less ▲]

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See detailEffet de la microfiltration d’épuration sur les composants influençant la qualité fromagère du lait
Ninane, Véronique; Grelet, Clément ULg; Dehareng, Frédéric et al

Poster (2014)

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See detailPolyplex Based On Polycarbonate Polymers For An Efficient Delivery Of An Anti-Angiogenic siRNA
Frère, Antoine ULg; Kawalec, Michal; Tempelaar, Sarah et al

Poster (2014)

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See detailCO spiral arms in the outer disk of HD 142527 with ALMA
Christiaens, Valentin ULg; Casassus, Simon; Perez, Sebastian et al

Poster (2014)

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See detailExperimental replication of Australian grinding stone implements
Hayes, Elspeth; Cnuts, Dries ULg; Fullagar, Richard et al

Poster (2014)

Until recently in Australia, lithic tool-use experiments were dominated by flaked stone with relatively few studies of ground-stone. This poster reports on a workshop, during which tool-use experiments ... [more ▼]

Until recently in Australia, lithic tool-use experiments were dominated by flaked stone with relatively few studies of ground-stone. This poster reports on a workshop, during which tool-use experiments were designed to document the wear traces associated with grinding various materials (n=7), different processing techniques (n=3), and sandstones of different hardness (n=5). The specific variables were selected to build a use-wear and residue reference library applicable to Australian archaeological grinding implements proposed for detailed functional analysis. [less ▲]

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See detailMultifunctionality of lipopeptide antibiotics from rhizobacteria
Ongena, Marc ULg; Hofte, M.

Poster (2014)

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See detailInfluence of mesoporosity in hematite films on water splitting efficiency
Toussaint, Caroline ULg; Cloots, Rudi ULg; Henrist, Catherine ULg

Poster (2014)

Solar energy is inexhaustible but variable during the day and the seasons. Photoelectrolysis of water (water splitting) convert this energy into hydrogen to obtain an energy that can be stored and ... [more ▼]

Solar energy is inexhaustible but variable during the day and the seasons. Photoelectrolysis of water (water splitting) convert this energy into hydrogen to obtain an energy that can be stored and transported on demand. Hematite is a promising material for the photoanode in water splitting because of its high stability in water, cheapness, abundance and its band gap that enables the absorption of visible light (Eg: 2,1eV). Nevertheless, hematite has also some drawbacks including a short diffusion length of holes and a bad electronic conductivity. We have implemented spin coating and templating to produce doped mesoporous hematite films. The nanostructuration can improve the performances in water splitting by reducing the diffusion length of holes and increasing the specific surface between the film and the electrolyte. To suppress the collapse of the mesoporosity at high temperature (requested for dopant activation), we have used a temporary silica confinement scaffold that reduces the crystallite growth. To show the impact of the nanostructure, we have compared three films (mesoporous, collapsed and dense) in terms of hematite content (elemental analysis), nanostructure (electron microscopy), crystallinity (X-ray diffraction) and water splitting efficiency. We have also test two thermal treatments. This study highlights the effect of the effective interface with the electrolyte, through the preservation or not of open porosity and the different evolutions of the nanostructures as a function of the heat treatment. [less ▲]

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See detailSeasonal variation in human executive brain responses
Meyer, Christelle ULg; Jaspar, Mathieu ULg; Muto, Vincenzo ULg et al

Poster (2014)

It is well established that cognition shows daily fluctuations with changes in circadian phase and sleep pressure. The physiological impact of season changes, which is well characterized in animals ... [more ▼]

It is well established that cognition shows daily fluctuations with changes in circadian phase and sleep pressure. The physiological impact of season changes, which is well characterized in animals, remains largely unexplored in human. Here we investigated the impact of seasonal variation on human cognitive brain function. This cross-sectional study,conducted in Liège (Belgium),spanned from May 2010 to October 2011. Following 8h in-lab baseline night of sleep, 30 volunteers (age 20.9+1.5; 15F)spent 42h awake under constant routine conditions(<5lux, semi-recumbent position, no time-cues). After12h recovery night, they underwent15minfMRI recording while performing a working memory 3-back task (3b) and a letter detection 0-back task (0b). Thus, fMRI data were acquired when volunteers had been in isolation under controlled conditionsfor 63h. Executive brain responses were isolated by subtracting 0b activity from 3b responses (3b>0b).Analysis tested seasonal influence on executive brain responses at the random effects level, using a phasoranalysis across the year.Inferences were conducted at p<0.05, after correction for multiple comparisons over a priori small volume of interest. Significanteffects of season on executive responses were detected inmiddle frontal and frontopolarregions, insula, and thalamus, with a maximum response at the end of summer and a minimum response at the end of winter.These brain areas are key regions for executive control and alertness. These results constitute the first demonstration that seasonality directly impacts on human cognitive brain functions. [less ▲]

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See detailEvaluation of bio-based additives in architectural paints
Wenkin, M.; Delvaux, M.H.; de Lame, C. et al

Poster (2014)

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See detailOptimization of cricket breeding production system for human food in Ratanakiri province (Cambodia)
Caparros Megido, Rudy ULg; Alabi, Taofic ULg; Nieus, Clément et al

Poster (2014)

Despite many natural resources, Cambodia is considered as a relatively poor country with a Gross National Income per capita averaging about 880 USD in 2012. Annâdya project in the Ratanakiri province ... [more ▼]

Despite many natural resources, Cambodia is considered as a relatively poor country with a Gross National Income per capita averaging about 880 USD in 2012. Annâdya project in the Ratanakiri province (Cambodia) aims to improve the food security and nutrition of smallholder households by introducing and facilitating the adoption of productive and environmentally sustainable agricultural technologies. The main purpose of this work was to optimize a cheap cricket breeding production system for local farmers to contribute to the reduction of protein deficiency and to create new source of incomes. Cricket development, Teleogryllus testaceus (Walker), was compared between seven diets composed of different ratio of aerial parts of taro, young cassava leaves, young cashew leaves, brown rice flour (with or without the addition of banana slices) and between the traditionally used chicken feed diet. Cricket mortality was relatively low on all diets (<10 %) excepted on the two cashew-based diets where mortality achieves 90 %. Mean adult body mass of the cricket was significantly higher on control diet (chicken feed) and on the two cassava-based diet (80% of cassava leave flour, 20% of brown rice with or without banana slices) than on the other diets (F = 20.87, P<0.001). The nutritional analyzes of the seven diets shows that the ideal diet should contain 19% protein, 5-6% fat, and a percentage of carbohydrates as high as possible. While the cricket mass body gain seems to be proportional to the carbohydrate content of the diet, the use of older cassava leaves, more rich in carbohydrates than the younger ones, is an interesting solution to substitute relatively expensive brown rice and banana slices also consumed by local population. In the future, consideration should be given to the adjustment of cassava leave maturity in function of the cricket growth stage as it is already done with chicken feed in Thai cricket farms. [less ▲]

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See detailSituation and perspective of entomophagy in Kinshasa
Nsevolo, Papy; Caparros Megido, Rudy ULg; Blecker, Christophe ULg et al

Poster (2014)

Eating edible insects in Republic Democratic of Congo is a tradition for centuries but a lack of knowledge remains about an actualized inventory of species consumed in the country. Moreover, a rigorous ... [more ▼]

Eating edible insects in Republic Democratic of Congo is a tradition for centuries but a lack of knowledge remains about an actualized inventory of species consumed in the country. Moreover, a rigorous taxonomic matching of the used vernacular name of edible insects and a precise characterization of the sector of entomophagy are still needed. According to our studies focused on the city of Kinshasa, 14 edible species were inventoried as regularly consumed. They belong respectively and by degree of importance to the Lepidoptera (46.7%), Isoptera (18.6%), Orthoptera (17.6%), Coleoptera (9.7%) and Hymenoptera (3.7%) orders. Generally 80.0% of the Kinshasa population consumes at least one species of insects 5 days per month. The key peoples in the edible insect sector are mostly women. The incomes generated by this activity contribute to the well being of households, to reduce poverty and food insecurity in the capital Kinshasa. Future studies should focus on sustainable ways of harvesting wild populations, the use of improved conservation practices, the enhancement of cottage industries for farming insects and the development of economically feasible ways of mass-rearing edible species. [less ▲]

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See detailSpectroscopic analysis of the remorin-lipid interactions at the moleculaer level
Nasir, Mehmet Nail ULg; Perraki, Artemis; Mongrand, Sébastien et al

Poster (2014)

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See detailModelling Farmers Credit Allocation Decisions and Impacts on Farms Technical Efficiency in Benin, West Africa
Sossou, Comlan ULg; Noma, Freddy; Yabi, Jacob

Poster (2014)

This paper models farmers credit allocation behaviours in schemes and analyses effects of the schemes on farms technical efficiency. Data were collected from 476 farmers using the multistage sampling ... [more ▼]

This paper models farmers credit allocation behaviours in schemes and analyses effects of the schemes on farms technical efficiency. Data were collected from 476 farmers using the multistage sampling procedure. The stochastic frontier truncated-normal with conditional mean model was used to assess allocation schemes effects on farms technical efficiency. A Tobit model reveals the impact of farmers' socio-demographic characteristics on efficiency scores. Results revealed that the revenue 2,262,566 Fcfa is positively correlated with acreage, quantity of labour and costs of fertilisers, insecticides, fertilisers. The average technical efficiency score is 0.675 (±0.137). The scores are diversely distributed across farms, with a median score equals to 0.713. Farmers behaviours respond to six credit investments schemes, which are categorised in two allocation contexts: in-farm and out-farm allocations. In the latter credit is invested towards social needs (weddings, traditional festivals, etc.) and household needs (health, education, housing etc.). Credit in-farm allocations are towards production inputs (land, labour, capital). The model showed that only one scheme impacted positively farms technical efficiency: scheme (e). It is the decision to invest the credit to purchase better quality of pesticides, herbicides, fertilisers, etc. The positive effect of the scheme (c) may be significant under conditions of farmers' education level improvement. Then, scheme (e) is a better investment for all farmers; either they have a high or low level of education. But the credit allocation to buy agricultural materials is positive only for the educated farmers; who are 53.53% of the surveyed farmers. The scores of efficiency are reduced by household size and gender of the household head. Therefore, households with less than 10 members, an educated man as head; are likely to improve their farms technical efficiency through two credit investments schemes: Credit×Capital and Credit×Intermediary-inputs. [less ▲]

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See detailMechanoreceptors in the anterior horn of the equine medial meniscus: an immunohistochemical approach.
Nemery, Elodie ULg; Gabriel, Annick ULg; Grulke, Sigrid ULg et al

Poster (2014)

Mechanoreceptors are “encapsulated sensory end-organs” involved in proprioceptive function. Given the high incidence of meniscal injuries in horses, the clinical interest in these mechanoreceptors ... [more ▼]

Mechanoreceptors are “encapsulated sensory end-organs” involved in proprioceptive function. Given the high incidence of meniscal injuries in horses, the clinical interest in these mechanoreceptors, particularly in the meniscus, and the lack of information concerning them in equine menisci, our objective was to study these corpuscles in the anterior horn of the equine medial meniscus, which is the most common localization reported for equine meniscal injuries. An immunohistochemical approach to detect Schwann cells and nerve fibres allowed us to localize and identify these corpuscles within the meniscus. Three types of mechanoreceptors were identified and localized between the abaxial quarter and the abaxial third of the meniscus: the Ruffini, Pacini and Golgi corpuscles. In conclusion, from a purely fundamental point of view, our work highlights for the first time the presence of MCR at the level of the anterior horn of the equine medial meniscus and proposes a classification based on specific immunocytochemical techniques. This morphological approach could serve as a basis for clinical studies, in order to evaluate the impact of these corpuscles on the poor sportive prognosis in equine meniscal tears. [less ▲]

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See detailAn unusual presentation for congenital cytomegalovirus infection
Hennuy, Nadège; PIERART; Demarche, Martine et al

Poster (2014)

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See detailEfficient method for a controlled deposition of Pd nanoparticles on a glassy carbon electrode
Olu, Pierre-Yves; Chatenet, Marian; Job, Nathalie ULg

Poster (2014)

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See detailMartian thermosphere scale height from SPICAM dayglow measurements
Stiepen, Arnaud ULg; Gérard, Jean-Claude; Bougher, Steve et al

Poster (2014)

We analyze the ultraviolet dayglow in the atmosphere of Mars through CO2+ and CO Cameron emissions. These emissions are accumulated on a large dataset of dayside grazing limb performed by the Spectroscopy ... [more ▼]

We analyze the ultraviolet dayglow in the atmosphere of Mars through CO2+ and CO Cameron emissions. These emissions are accumulated on a large dataset of dayside grazing limb performed by the Spectroscopy for Investigation of Characteristics of the Atmosphere of Mars (SPICAM) instrument on board the Mars Express spacecraft. The temperature of the Martian upper atmosphere can be retrieved from these limb emission profiles. We present discussion on the validity domain for such retrieval. We also show evidence for local (spatial and temporal) variability in the scale height of the atmosphere at the altitude of these emissions. [less ▲]

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See detailPréservation de la thymopïèse dans le grand âge
RICOUR, Céline ULg; de saint hubert, Marie; Martens, Henri ULg et al

Poster (2014)

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