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See detailStatistical analysis of low-flow based on short time series. The case of Wallonia
Verstraete, Arnaud ULg; Gailliez, Sébastien; Degre, Aurore ULg

in Geophysical Research Abstracts (2011), 13

The floods have always been the main concern resulting of extreme weather conditions. Now droughts and low flows are more and more recognized as risk situations due to the huge consequences of water ... [more ▼]

The floods have always been the main concern resulting of extreme weather conditions. Now droughts and low flows are more and more recognized as risk situations due to the huge consequences of water shortage. Furthermore, the changing climate context constitutes a new threat even if the uncertainty in low-flows evolution remains high. In Wallonia (Southern part of Belgium), a knowledge gap remains on statistical analysis of low-flows. In this paper, we present a study of historical data in Walloon Region and the first steps of their statistical analysis. Wallonia is one of the three regions of Belgian federal state. It covers an area of 17000 km² and spreads on 4 districts (Meuse, Escaut, Rhin, Senne). The watercourses are divided in navigable watercourses (700km), not navigable watercourses that are listed in 3 categories (14300km) and streams that are not navigable and not listed (4000km). Hydrological monitoring has a short history in Wallonia. The first monitoring site was installed in 1960. It consisted in a limnimetric scale and daily manual readings. Since 1974, hourly data are recorded. The number of measurement sites reached 244 stations in 2011. About 60 % of the monitoring sites have less than 20 years of hourly data. A qualitative analysis of monitoring stations led us to disregard 184 stations. The main quality problems were important discharge rating curve extrapolation, algae development in summer or low flow inferior to 5l/s. In preparation for a statistical analysis of low-flows, the old manual daily readings were analyzed. Unusable in high flow situations, they still hold practical and usable information during drought. This analysis allowed us to extend the registration period up of 7 stations and to recover 16 stations. There were lots of missing data during the 1960-1994 period, due to a poor management of the monitoring network. A yearly hydrograph analysis leads us to keep years of partial measurement when the gaps were found to be out of the low-flow period. The monitoring sites presenting more than 20 years of readings were selected for the statistical analysis. A homogeneity test was performed. Finally 64 out of 244 monitoring sites are kept for the frequency analysis. The indicators used to characterize low-flows are the popular Q95 and MAM7. Five below bounded distributions are tested with the HYFRAN software: Weibull (2 parameters), log-normal 2 parameters and 3 parameters, Gamma and Pearson type III. The parameters of the laws are estimated by the maximum likelihood estimation. The selection of the three best laws is performed for each site thanks to three Bayesian criterions proposed by HYFRAN. Then the distribution that fits the best the data is visually chosen. The results of the adjustment method are the same for the two indicators. The Gamma distribution is the most used followed by the lognormal with 2 parameters. However in some cases a law of three parameters is more appropriate. This preliminary work gives a first analysis of low-flows statistics in Wallonia. Yet a lot of missing data or short recording duration still limits our knowledge, this analysis allows us to progress towards best management practices in rivers and watersheds. [less ▲]

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See detailMaintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis
Reginster, Jean-Yves ULg; Kaufman, J. M.; Devogelaer, J. P. et al

in Arthritis and Rheumatism (2011), 63(S10), 436

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See detailNMHC Climatology from Central European Mountain Observatories
Plass-Duelmer, C.; Reimann, S.; Wallasch, M. et al

in Geophysical Research Abstracts (2011), 13

NMHC (non-methane hydrocarbons) are a major group of atmospheric trace gases with impact on photochemical processes in the atmosphere, especially oxidant formation with ozone being the most prominent of ... [more ▼]

NMHC (non-methane hydrocarbons) are a major group of atmospheric trace gases with impact on photochemical processes in the atmosphere, especially oxidant formation with ozone being the most prominent of them, and contributions to SOA (secondary organic aerosols). By this, they are coupled to climate issues via the oxidizing capacity of the atmosphere, the greenhouse gas ozone and aerosol effects. NMHC monitoring was initiated in Europe in the “Tropospheric Ozone Research” project (1988-1995), and it was continued in EMEP and GAW (Global Atmosphere Watch) where it is an ongoing initiative which recently has been reinforced (GAW Report 171). In this presentation we will focus on time series from Central European mountain stations (46-49°N, 7-13°E): Hohenpeissenberg (985 m, DWD, Germany, 1998-ongoing), Rigi (1031 m, EMPA, Switzerland, 2003-ongoing), Junfraujoch (3580 m, EMPA, Switzerland, 2000-ongoing, and ULg (FTIR), Belgium, 1984-ongoing), Zugpitze (2650 m, UBA, Germany, 2000-ongoing), Schauinsland (1205 m, FZ-Jülich (1989-94), and UBA, Germany, 2004-ongoing), Brotjacklriegel (1016 m, UBA, Germany, 2000-2004), Donon (775 m, EMD, France, 1997-2007). Most sites used weekly flask samples but also on-line measurements were carried out with higher time resolution within the former TOR project and in the more recent time series at Hohenpeissenberg, Rigi, and Jungfraujoch. All samples were analysed by GC. Additionally to these GC measurements, a time series of column integrated acetylene and ethane by FTIR (Fourier Transform InfraRed spectrometry) is available from Jungfraujoch, from 1984 onwards. We focus here on time series of monthly averages of anthropogenic hydrocarbons over the 1997-2009 time period. They show quite similar patterns among the various stations over the whole period with pronounced seasonal cycles. Significantly lower mixing ratios were measured at the highest elevated sites, the Zugspitze and Jungfraujoch. Differences between the lower mountain sites (775-1200 m) are on first view surprisingly small. Generally, the differences between the high altitude and the other mountain sites are lowest in summer due to enhanced vertical mixing and thermal upslope winds. Downward trends for anthropogenic hydrocarbons are very similar at the various stations and are 2 %/yr for C2-C3 alkanes (+/- 1%), 3-6 %/yr for C4-C7 alkanes (+/- 2%), 2-3%/yr for C2-C3 alkynes and ethene (+/- 2%), 4 % /yr for propene and benzene (+/- 2%), and 5-10%/yr for toluene and xylenes (+/-3 and 5%, respectively). [less ▲]

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See detailA phase 3 study of the efficacy and safety of Denosumab in men with low bone mineral density : design of the ADAMO
Orwoll, E.; Stubbe Teglbjaerg, Ch; Langdahl, B. et al

in Journal of Bone and Mineral Research (2011), 26(S1), 511

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See detailReduction in incidence of vertebral fractures with once yearly zoledronic acid in men with osteoporosis
Boonen, S.; Kaufman, J. M.; Reginster, Jean-Yves ULg et al

in Journal of Bone and Mineral Research (2011), 26(S1), 23

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See detailRapid changes of aromatase activity in discrete brain regions following social interactions
de Bournonville, Catherine ULg; Ball, Gregory, F.; Balthazart, Jacques ULg et al

in Trabajos del Instituto Cajal (2011), LXXXIII

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See detailRetrieving semantic information from faces and voices
Barsics, Catherine ULg

in In L. Carlson, C. Hoelscher, & T.F. Shipley (Eds.), Proceedings of the 33rd Annual Conference of the Cognitive Science Society (2011)

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See detailDenosumab therapy in postmenopausal women with osteoporosis : results from the first two years of the freedom trial extension
Bone, H. G.; Chapurlat, R.; Brandi, M. L. et al

in Endocrine Reviews (2011), 32

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See detailSafety and Performance of Stochastic Targeted (STAR) Glycemic Control of Insulin and Nutrition – First Pilot Results
Shaw, Geoffrey M.; Le Compte, Aaron; Evans, Alicia et al

in Intensive Care Medicine (2011)

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See detailMaxwell rigidity and topological constraints in amorphous phase-change networks
Micoulaut, M.; Otjacques, C.; Raty, Jean-Yves ULg et al

in AIP Conference Proceedings (2011), 1393

By analyzing first-principles molecular-dynamics simulations of different telluride amorphous networks, we develop a method for the enumeration of radial and angular topological constraints, and show that ... [more ▼]

By analyzing first-principles molecular-dynamics simulations of different telluride amorphous networks, we develop a method for the enumeration of radial and angular topological constraints, and show that the phase diagram of the most popular system Ge-Sb-Te can be split into two compositional elastic phases: a tellurium rich flexible phase and a stressed rigid phase that contains most of the materials used in phase-change applications. This sound atomic scale insight should open new avenues for the understanding of phase-change materials and other complex amorphous materials from the viewpoint of rigidity. [less ▲]

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See detailGlucosamine sulfate for structure modification in osteoarthritis : fact of fantasy ?
Reginster, Jean-Yves ULg

in Ortopedia, Traumatologia, Rehabilitacja (2011), 13(S1), 44

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See detailMethod for the Measurement of Dechlorane 602 in Human Serum
Brasseur, Catherine ULg; Pirard; Focant, Jean-François ULg

in Organohalogen Compounds (2011), 73

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See detailEffects of different spatial interpolators on the estimate of extreme precipitations
Ly, Sarann ULg; Beckers, Eléonore ULg; Charles, Catherine ULg et al

in Geophysical Research Abstracts (2011), 13

The design values of the areal precipitation are needed for engineer to manage vital elements of our infrastructure. The areal precipitation can be generated by different interpolation methods. The ... [more ▼]

The design values of the areal precipitation are needed for engineer to manage vital elements of our infrastructure. The areal precipitation can be generated by different interpolation methods. The problem involves choosing the interpolation method that we should use to estimate the extreme event. This work aimed at analyzing the effects of different interpolation methods on the estimate of extreme events of daily areal precipitations at catchment scale. The extreme rainfalls were estimated using areal daily rainfall interpolated by several interpolation methods (Thiessen polygon, Inverse Distance Weighting, Ordinary Kriging, Universal Kriging, Kriging with an External Drift and Ordinary Cokriging). We used thirty-years-long daily time series and different density of rain gages (from 4 to 70 rain gages). Our study is located in the Ourthe and Ambleve catchment area (2908 km²) in the southern part of Belgium). Spatial interpolation with the geostatistical and Inverse Distance Weighting algorithms outperformed considerably interpolation with the Thiessen polygon. Kriging with an External Drift and Ordinary Cokriging presented the highest Root Mean Square Error between the geostatistical and Inverse Distance Weighting methods. Ordinary Kriging and Inverse Distance Weighting were considered to be the best methods, as they provided smallest Root Mean Square Error for nearly all cases. However, it’s not really the case of extreme estimates for particular return period. The extreme daily rainfall, corresponding to return periods of 25, 50 and 100 years, were computed by fitting of a statistical model to the series of maximum annual precipitation. These estimates were conducted using HYFRAN which allows us to fit 16 different statistical models, in 2 or 3 parameters. The most known are the models of Gumbel, Gamma, Weibull, exponential, Pareto, lognormale, Pearson III and GEV. Our results showed that the behaviour of extreme daily areal rainfall in this area was best described via the Gumbel and lognormal distributions. Using 70 rain gages, little differences in extreme rainfall were observed between the interpolation methods. The estimates from these methods were in the area of 95% confidence intervals of the estimates using the Thiessen polygon. However, when the number of rain gages diminishes, the Universal Kriging and Kriging with External drift methods produced extreme estimates outside the area of 95% confidence intervals of the estimates using the Thiessen polygon with all available stations. The analysis described here provides a means to choose the interpolation method in view to calculate extreme events. It shows to engineers or hydrologists the need for a particular care when working in the regions of sparse data. [less ▲]

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See detailION MOBILITY – MASS SPECTROMETRY AS A NEW APPROACH FOR THE SCREENING OF PESTICIDE RESIDUES IN FOOD
Goscinny, Séverine ULg; Touilloux, Romain; Joly, Laure et al

in Organohalogen Compounds (2011)

Pesticide residue analysis requires methods that can determine hundreds of compounds at low levels in complex food matrices. This challenge has given rise to multi residue methods, the only efficient ... [more ▼]

Pesticide residue analysis requires methods that can determine hundreds of compounds at low levels in complex food matrices. This challenge has given rise to multi residue methods, the only efficient analytical approach. This type of analytical method entails a “generic” extraction followed by a soft or no purification step to avoid any analytes looses. With over a 1000 active compounds with different physical chemical properties, gas and liquid chromatography are used as complementary separative techniques. In the past decade, the determination has been performed on tandem mass analyzers, a powerful tool to overcome co-eluting compounds with excellent sensitivity. Nevertheless, these instruments can guarantee these results per acquisition cycles for more or less 150 compounds. This represents a serious limitation when the number of pesticides to be sought for monitoring and MRL enforcement is growing each year. As multiple injections from the same sample are not viable for laboratories, alternative options have to be explored. We propose the investigation of ion mobility (IM) coupled with mass spectrometry as a new approach for pesticide residue analysis in food. [less ▲]

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See detailLevels of PCDD/Fs and PCBs in Camel Milk (Camelus Bactrianus and Camelus Dromedarius) from Kazakhstan
Konuspeyeva, G; Faye, B; De Pauw, Edwin ULg et al

in Organohalogen Compounds (2011), 73

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See detailBilan 2010 des activités du Laboratoire de dendrohcornologie du Centre européen d'archéoémétrie (CEA) de l'Université de Liège
Hoffsummer, Patrick ULg; Maggi, Christophe ULg

in Archeologia Mediaevalis, archéologie du Moyen Âge et des Temps modernes dans les trois régions belges et les pays limitrophes (2011), 34

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See detailLes modèles de l'entrepreneuriat social en Asie de l'Est
Defourny, Jacques ULg

in Social Enterprise Journal (2011), 7(1), 86-111

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See detailEnumeration and decidable properties of automatic sequences
Charlier, Emilie ULg; Rampersad, Narad; Shallit, Jeffrey

in Lecture Notes in Computer Science (2011), 6795

We show that various aspects of k-automatic sequences — such as having an unbordered factor of length n — are both decidable and effectively enumerable. As a consequence it follows that many related ... [more ▼]

We show that various aspects of k-automatic sequences — such as having an unbordered factor of length n — are both decidable and effectively enumerable. As a consequence it follows that many related sequences are either k-automatic or k-regular. These include many sequences previously studied in the literature, such as the recurrence function, the appearance function, and the repetitivity index. We also give a new characterization of the class of k-regular sequences. Many results extend to other sequences defined in terms of Pisot numeration systems. [less ▲]

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See detailInfluence of practice characteristics on injury risk in young athletes
Frisch, Anne ULg; Urhausen, Axel; Seil, Romain et al

in British Journal of Sports Medicine (2011), 45

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See detailLack of P2X1 ion channels increases endotoxemia associated coagulation and organ damage through neutrophil hyperresponsiveness.
Lecut, Christelle ULg; Faccinetto, Céline ULg; Evans, Richard J et al

in Journal of Thrombosis and Haemostasis [=JTH] (2011), 9(suppl S2),

ATP-gated P2X1 ion channels contribute to arterial thrombosis by amplifying platelet activation. In the search for novel anti-platelet strategies, targeting P2X1 ion channels is appealing. However, in ... [more ▼]

ATP-gated P2X1 ion channels contribute to arterial thrombosis by amplifying platelet activation. In the search for novel anti-platelet strategies, targeting P2X1 ion channels is appealing. However, in this study we found that lack or inhibition of P2X1 channels enhanced neutrophil respiratory burst activity ex vivo. <br />To study the consequence of P2X1 deficiency on neutrophil function in vivo, P2X1-/- mice were used in a model of endotoxin-induced sepsis. Upon injection of lipopolysaccharides (LPS), plasma myeloperoxidase (MPO) concentrations reached higher levels in the P2X1-/- mice, and circulating neutrophils expressed higher levels of surface CD11b compared to wild-type mice. Neutrophil relocalization into the lungs of LPS-treated P2X1-/- mice was also significantly augmented, reflecting a higher activation state of P2X1-/- neutrophils under conditions of sepsis. Accordingly, more extensive lipid peroxidation was observed in the liver of LPS-treated P2X1-/- mice, indicative of exaggerated oxidative damage. Concomitantly, the levels of thrombin-antithrombin complexes were higher in the plasma of LPS-treated P2X1-/- mice and thrombocytopenia was worsened as compared to wild type mice. Elevated numbers of microthrombi were also found in the lungs of these mice. These observations coincided with a higher susceptibility of P2X1-/- mice to LPS-induced septic shock than wild type animals. <br />Our results strongly suggest that P2X1 ion channels play a protective role in sepsis by negatively regulating systemic neutrophil activation, thereby limiting oxidative damage, activation of coagulation and platelet accumulation into the lungs. Therefore, since antagonists of P2X1 ion channels may not only target platelets but also affect neutrophils, inhibiting these channels in the highly inflammatory environment of severe sepsis or of acute coronary syndromes might be detrimental. [less ▲]

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See detail2D DIGE, label free quantification, principal component and mass spectrometry analysis for biomarkers discovery in MCF-7/BOS cells exposed to 17β-estradiol and endocrine disruptors.
Collodoro, Mike ULg; Lemaire, Pascale; Eppe, Gauthier ULg et al

in Organohalogen Compounds (2011)

Endocrine system disruption has become a subject of great interest over the last few decades, since it has become evident that natural and also synthetic substances can mimic or reduce the activity of ... [more ▼]

Endocrine system disruption has become a subject of great interest over the last few decades, since it has become evident that natural and also synthetic substances can mimic or reduce the activity of endogenous hormones. Compounds with estrogenic activity are an important family of potential endocrine disruptors that have to be monitored either in the food chain or in the environment. Estrogens are known to induce or promote hormonal dependent cancers, to reduce sperm counts and fertility in men and generate the feminization of exposed wildlife populations. The rapid screening of unwanted chemicals in the food chain is beset by difficulties. The number of toxic compounds is very large and no universal method can cope with their diversity. In this work, emergent differential proteomic techniques are used to discover a set of biomarkers for the development of a multiple estrogen contaminants screening test. [less ▲]

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See detailEvaluation de la performance des muscles extenseurs du tronc
Demoulin, Christophe ULg; GROSDENT, Stéphanie ULg; Crielaard, Jean-Michel ULg et al

in Kinesitherapie Revue (2011), 111

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See detailImpact of thresholding techniques on X-ray soil microtomogram analyses
Beckers, Eléonore ULg; Léonard, Angélique ULg; Beekkerk van Ruth, Jöran ULg et al

in Geophysical Research Abstracts (2011), 13

Using X-ray microtomography, 3D soil structure can be visualised and analysed through useful factors like pore size distribution, shape, connectivity, orientation, etc. X-ray scans yield grey-level 2D ... [more ▼]

Using X-ray microtomography, 3D soil structure can be visualised and analysed through useful factors like pore size distribution, shape, connectivity, orientation, etc. X-ray scans yield grey-level 2D images, which can be recombined to form 3D structures. Treatments of the grey-level images can consist of either a binarization -distinguishing soil and pores- or a permeability level attribution directly linked to the grey-level values. The latter leads to problems in order to assign a permeability for each point (in soil a same grey level value can be assigned to points with a different permeability), as well as to analyse the 3D structure. On the other hand, treatment of black and white 3D structures is well-handled. However, the impact of the choice of one thresholding technique on the resulting images has already been demonstrated. Moreover, thresholding methods are various and numerous. Many of them are based on the image histogram analysis. But because of the soil complexity, the relevance of these techniques becomes debatable, with a risk of producing non reliable images. We propose to palliate this with a simple new algorithm based on physical measurements: it uses a loop fixing the threshold value in order to match the measured porosity for each sample. In this communication, our point is to highlight the impact of different thresholding techniques on the analysis and interpretation of our soil microtomograms. The underlying questions could be: Does the thresholding method influence our conclusions? Are the results depending on the sample itself or on the methodology? In order to answer these questions we tested the Otsu technique and our physically based algorithm. Soils samples were removed from the upper layer (Ap horizon) of a silty soil (Gentinnes, Brabant Walloon, Belgium) in plots with different management practices. In fact, since 2004, the field has been cultivated in conventional tillage (CT) or reduced tillage (RT). In order to empty the meso- and macroporosity, samples were placed under a 1.5 MPa pressure (Richards apparatus). Samples were then scanned by X-ray microtomography using a Skyscan-1172 high-resolution desktop micro-CT system (Skyscan, Kontich, Belgium). The cone beam source operated at 100 kV, using an aluminium filter. The detector configuration, i.e. 1048x2000 pixels with a 16-bit X-ray camera, and the distance source-object-camera were adjusted to produce images with a pixel size of 17 µm. Porosity was measured for each scanned sample. Then the threshold methods -the Otsu technique on one hand and our developed algorithm on the other - were applied, and morphological factors were calculated for both methods. A comparison of the first results shows a threshold influence on average porosity and number of pores, but also on connectivity factors and size distribution. The apparent porosity of the images, as well as connectivity, is underestimated with the Otsu technique. Despite the fact that the changes induced by thresholding are more important for RT than CT, global conclusions about the comparison of these agricultural practices are approximately the same in this case. However, differences between tillage systems are less important with the Otsu method, confirming the impact of choosing the adapted threshold method. [less ▲]

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See detailExperimental characterization and constitutive modeling of TA6V mechanical behavior in plane strain state at room temperature
Gilles, Gaëtan ULg; Tuninetti Vásquez, Victor ULg; Ben Bettaieb, Mohamed ULg et al

in AIP Conference Proceedings (2011), 1383

This paper presents an experimental and theoretical study of the quasi-static behavior of TA6V titanium alloy in plane strain state. In order to quantify the anisotropy of the material, tests were carried ... [more ▼]

This paper presents an experimental and theoretical study of the quasi-static behavior of TA6V titanium alloy in plane strain state. In order to quantify the anisotropy of the material, tests were carried out at room temperature on specimens cut out from a sheet along three loading directions. The initial yield locus is described by the phenomenological CPB06ex3 criterion and Voce’s type isotropic hardening is used. Finite element simulations are performed and compared with the experiments. [less ▲]

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See detailFuran formation in baby food model system via lipid oxidation and sugar degradation
Owczarek-Fendor, Agnieszka; De Meulenaer, Bruno; Scholl, Georges ULg et al

in Communications in Agricultural and Applied Biological Sciences (2011), 76(1), 107-110

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See detailRELATIONS ENTRE GAIN BARO-REFLEXE ET STRESS PULSATILE CHEZ LE PATIENT DIABETIQUE DE TYPE 1
SCHEEN, André ULg; MARCHAND, Monique ULg; PHILIPS, Jean-Christophe ULg

in Archives des Maladies du Coeur et des Vaisseaux (2011), hors série 3

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See detailTraitement durant cinq ans par denosumab (DMAb) chez des femmes ménopausées ostéoporotiques : résultats d'efficacité des deux premières années de l'extension de l'essai FREEDOM
Chapurlat, R.; Roux, C.; Papapoulos, S. et al

in Revue du Rhumatisme (2011), 78(S5), 214

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See detailTrend evolution and seasonal variation of tropospheric and stratospheric carbonyl sulfide (OCS) above Jungfraujoch
Lejeune, Bernard ULg; Mahieu, Emmanuel ULg; Duchatelet, Pierre ULg et al

in Geophysical Research Abstracts (2011), 13

Carbonyl sulfide (OCS) is the most abundant sulfur-containing trace gas in the atmosphere and accounts for a substantial portion of the sulfur in the stratospheric aerosol layer which influences the ... [more ▼]

Carbonyl sulfide (OCS) is the most abundant sulfur-containing trace gas in the atmosphere and accounts for a substantial portion of the sulfur in the stratospheric aerosol layer which influences the Earth’s radiation budget and stratospheric ozone chemistry. The major identified OCS sources are oceans and anthropogenic emissions, while atmospheric loss and uptake by vegetation and soils constitute the main OCS sinks. The uptake by vegetation strongly influences the distribution and seasonality of OCS throughout most of the Northern Hemisphere, just like for CO2. Montzka et al. (2007) pointed that atmospheric OCS measurements have the potential to constrain the biomass Gross Primary Production (GPP). Unfortunately, there remain large uncertainties on some components strengths of the atmospheric OCS budget. A recent work by Suntharalingam et al. (2008) showed that uptake by plants has been strongly underestimated in actual balanced budgets, suggesting that additional significant OCS sources have still to be identified. In order to improve our understanding of the different processes governing seasonal and inter-annual OCS variability, a new approach has been developed and optimized, using the SFIT-2 algorithm, to retrieve atmospheric abundance of OCS from high-resolution ground-based infrared solar spectra. Our observations are recorded on a regular basis with Fourier Transform Infrared spectrometers (FTIRs), under clear-sky conditions, at the NDACC site (Network for the Detection of Atmospheric Composition Change, http://www.ndacc.org) of the International Scientific Station of the Jungfraujoch (Swiss Alps, 46.5°N, 8.0°E, 3580m asl). Information content analysis of the retrieved OCS products shows us that we are able to distinguish between tropospheric and stratospheric partial column contributions for this species. Thanks to our unique observational database, we have produced an updated OCS long-term trend from 1995 to 2010, representative for both the troposphere and stratosphere at northern mid-latitudes. In this contribution, we will present and critically discuss the recent OCS trend evolution, in particular the end of the slow decline of its abundance observed in 2002 and the maximum reached in 2008. In addition to the OCS inter-annual variations, we will analyze the OCS seasonal cycle during the 15 last years. We will also compare our results with simulations of seasonal OCS variations issued from a 3D global atmospheric chemical transport model (CTM), in order to try to quantify the individual contribution of the various processes playing a role in the Jungfraujoch OCS variability and influencing its atmospheric abundance. [less ▲]

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See detailConstraining statistical-model parameters using fusion and spallation reactions
Mancusi, D.; Charity, R. J.; Cugnon, Joseph ULg

in European Physics Journal: Web of conferences (2011)

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See detailTrend and lifetime of sulfur hexafluoride at mid-latitudes deduced from ACE-FTS occultation measurements
Mahieu, Emmanuel ULg; Duchatelet, Pierre ULg; Zander, Rodolphe ULg et al

in Geophysical Research Abstracts (2011), 13

Sulfur hexafluoride (SF6) is one of the strongest greenhouse gases on a per molecule basis, with a global warming potential of 22800 (100-yr horizon). This is an extremely stable gas in the atmosphere ... [more ▼]

Sulfur hexafluoride (SF6) is one of the strongest greenhouse gases on a per molecule basis, with a global warming potential of 22800 (100-yr horizon). This is an extremely stable gas in the atmosphere, which results in a very long lifetime, with large uncertainties. The value adopted by IPCC is 3200 years, but some studies suggest shorter lifetimes, as low as 800 years. Surface concentrations are now about 7 ppt, with reported trends indicating a steady and strong increase of 0.3 ppt/yr. Most emissions are of anthropogenic origin, related to its use as an insulator in high-voltage electrical installations. Secondary contributions result from magnesium and aluminum production as well as from the manufacturing of semiconductors (see e.g. Levin et al., 2010; Rigby et al., 2010 and references therein). In this contribution, we use occultation measurements performed by the ACE-FTS (Atmospheric Chemistry Experiment Fourier Transform Spectrometer) instrument, launched in August 2003 onboard the Canadian SCISAT satellite (Bernath et al., 2005). ACE-FTS is still in operation to date, with no significant degradation in its performance. This spectrometer achieves a spectral resolution of 0.02 cm-1 in the broad 750-4400 cm-1 range which covers the unresolved nu-3 band Q branch of SF6 centered at 947.9 cm-1. Signal-to-noise ratios of 200-300 are typically obtained in the spectral region of interest. Version 3 retrievals performed by University of Waterloo give volume mixing ratio profiles of SF6 in the 11-32 km altitude range. We consider all available sunrise and sunset occultation measurements obtained at midlatitudes in both hemispheres to derive the trend of SF6 in the lower stratosphere, from late February 2004 onwards. Consistency between both hemispheres will be investigated. In addition, concurrent N2O measurements are used to evaluate the atmospheric lifetime of SF6, following a method used previously for other long-lived gases (e.g. Zander et al, 1996). Comparisons with trends derived from in situ surface measurements or from ground-based remote-sensing observations (e.g. at the Jungfraujoch station, 46.5ºN) are also included. [less ▲]

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See detailInvestigation of the efficiency of the Ti555 compared with TA6V alloy in the case of an aeronautic application
Ben Bettaieb, Mohamed ULg; Van Hoof, T.; Zhang, Lihong ULg et al

in The 12th World Conference on Titanium Ti-2011 (2011)

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See detailFinite orbits of language operations
Charlier, Emilie ULg; Domaratzski, Michael; Harju, Tero et al

in Lecture Notes in Computer Science (2011), 6638

We consider a set of natural operations on languages, and prove that the orbit of any language L under the monoid generated by this set is finite and bounded, independently of L. This generalizes previous ... [more ▼]

We consider a set of natural operations on languages, and prove that the orbit of any language L under the monoid generated by this set is finite and bounded, independently of L. This generalizes previous results about complement, Kleene closure, and positive closure. [less ▲]

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See detailRécit de paroles et expériences de l’altérité dans Le Monde vrai de Marivaux
Tilkin, Françoise ULg

in Philologia (2011), XXI(Supplementum I), 281-290

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See detailTaux sérique de vitamine D et réponse au traitement par alendronate
Roux, C.; Chartier, C.; Boonen, S. et al

in Revue du Rhumatisme (2011), 78(S5), 102

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See detailOscillations in rapidly rotating stars
Reese, Daniel ULg

in Astronomische Nachrichten (2010, December 01), 331

Spurred by the spectroscopic and interferometric observations of rapidly rotating stars and the highly accurate pulsation data coming from asteroseismology space missions, theoreticians have spent many ... [more ▼]

Spurred by the spectroscopic and interferometric observations of rapidly rotating stars and the highly accurate pulsation data coming from asteroseismology space missions, theoreticians have spent many years developing models for such stars and studying their oscillations. This has led to the discovery of new phenomena and new types of pulsation modes. In what follows, a review is given of the different methods used to model the effects of rotation on stellar pulsations, as well as a description of these effects on inertial, gravito-inertial, r and acoustic modes. [less ▲]

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See detailApplication of magnetic susceptibility to the Maastrichtian-Eocene phosphatic deposits of Séjla section in Gafsa-Métlaoui basin (Southern Tunisia)
Akermi, Souha; Abdallah, H.; Da Silva, Anne-Christine ULg et al

in Geologica Belgica (2010, December), 13(4),

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See detailMagnetic susceptibility records in recent (Cenozoic) and Ancient (Devonian – Palaeozoic) mound systems.
Foubert, Anneleen; Da Silva, Anne-Christine ULg; Boulvain, Frédéric ULg et al

in Geologica Belgica (2010, December), 13(4),

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See detailMagnetic susceptibility on different sedimentary settings, example from the Devonian of Belgium
Da Silva, Anne-Christine ULg; Mabille, Cédric; Boulvain, Frédéric ULg

in Geologica Belgica (2010, December), 13(4),

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See detailDetailed sedimentological study and magnetic susceptibility of and Eifelian mixed ramp-related system in the Eifel area
Pas, Damien ULg; Mabille, Cédric; Aretz, Markus et al

in Geologica Belgica (2010, December), 13(4),

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See detailCellular uptake of long-circulating pH-sensitive liposomes: evaluation of the liposome and its encapsulated material penetration in cancer cells
Ducat, Emilie ULg; Deprez, Julie ULg; Peulen, Olivier ULg et al

in Drug Discovery Today (2010, December), 15(23-24), 1079-1114

Print 3G, a peptidic antagonist of oncoprotein involved in breast cancer, could reduce the angiogenic development of breast tumors, leading to tumor dormancy. The necessity of intravenous administration ... [more ▼]

Print 3G, a peptidic antagonist of oncoprotein involved in breast cancer, could reduce the angiogenic development of breast tumors, leading to tumor dormancy. The necessity of intravenous administration of Print 3G led to the development of long-circulating liposomes as drug carriers. Pegylated liposomes, too large to be collected by fenestrated organs, accumulate passively in solid tumors thanks to the EPR effect. The strategy was to combine the protective properties of PEG with the transfection properties of pH-sensitive lipids which could promote the uptake of liposomes by cells and avoid lysosomal sequestration and degradation of entrapped materials such as peptides. In this study, we compare two formulations in terms of cellular uptake using confocal microscopy. The first one is composed of SPC:CHOL:mPEG-750-DSPE (47:47:6), used as "standard" liposomes, and the second one of DOPE:CHEMS:CHOL:mPEG750-DSPE (43:21:30:6), used as pH-sensitive liposomes. First, we evaluated the penetration of an encapsulated model molecule, calcein, in Hs578t human breast cancer epithelial cells. When calcein was encapsulated in standard liposomes, its penetration was effective only in few cells. On the contrary, a majority of cells were fluorescent when calcein-loaded pH-sensitive liposomes were applied for 3 hours on cells. Secondly, we studied the penetration of liposomes themselves in Hs578t cells using 25-[(nitrobenzoxadiazolyl)methylamino]nor-cholesterol (NBD-CHOL) as a fluorescent marker of the phospholipid membrane. The obtained results were comparable to those obtained with calcein: a higher penetration of liposome was observed for pH-sensitive liposomes. Finally, the cellular uptake of liposomes using both NBD-CHOL and rhodamine encapsulated in the inner cavity of vesicles was evaluated with Hs578t cells and compared with WI26 human diploid lung fibroblast cells. Thanks to this experiment, we could follow simultaneously the cell distribution of the encapsulated material and of the liposome itself. Confocal pictures obtained with pH-sensitive liposomes on both WI26 and Hs578t cells allow us to visualize the co-localized red and green colors of rhodamine and NBD-CHOL, with a higher concentrated area near the nucleus. In comparison with "standard" liposomes, we observed a higher penetration of the encapsulated material and of the liposome itself in breast cancer cells. Moreover, we visualized a colocalization near the nucleus of liposomes components. Concerning results obtained with fibroblastic cells, there was no difference in terms of cellular uptake between the two formulations. In perspective, we would like to compare these results, obtained with model molecules, with experiments performed with biotinylated Print 3G to assess its cellular distribution. Moreover, it would be interesting to correlate results obtained with confocal microscopy with a possible increase of the peptide efficacy against cancer cells when it is encapsulated in long-circulating pH-sensitive liposomes. [less ▲]

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See detailRehabilitation in osteoporosis
Bruyère, Olivier ULg

in Proceedings of the annual congress of the Royal Belgian Society of Physical and Rehabilitation medicine (2010, December)

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See detailEvolution of the Kızılırmak river and its interaction with the North Anatolian Fault, Turkey
Drab, Laureen; Hubert, Aurelia ULg; Benedetti, Lucilla et al

in AGU Abstract (2010, December)

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See detailMagnetic susceptibility correlation of km-thick Eifelian-Frasnian sections (Belgium-Czech Republic)
Boulvain, Frédéric ULg; Da Silva, Anne-Christine ULg; Mabille, Cedric et al

in Geologica Belgica (2010, December), 13(4), 5-7

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See detailAltération du mouvement lombo-pelvien chez les danseurs. Valeur prédictive et interprétation clinique
Roussel, Nathalie; Demoulin, Christophe ULg

in Kinesitherapie Revue (2010, December), 108

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See detailÉvaluation clinique du patient lombalgique chronique : état des lieux
Roussel, Nathalie; Demoulin, Christophe ULg

in Kinesitherapie Revue (2010, December), 108

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See detailLe renforcement instrumentalisé des muscles du tronc
Vanderthommen, Marc ULg; Demoulin, Christophe ULg; Grosdent, Stéphanie ULg et al

in Kinesitherapie Revue (2010, December), 108

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See detailControl of hypertension in a kidney transplanted population : the EPARA study
Gellner, Karen; Saint-Remy, Annie ULg; Weekers, Laurent ULg et al

in Acta Clinica Belgica (2010, November 27), 66(1), 79

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See detailDe la Carte des Sols de la Belgique à la Carte Numérique des Sols de Wallonie : vers des Systèmes Régionaux d'Information sur les Sols et leurs propriétés
Legrain, Xavier ULg; Demarcin, Pierre ULg; Colinet, Gilles ULg et al

in Bulletin du groupe francophone humidimétrie et transferts en milieux poreux (2010, November 25), 56

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See detailSUIVI D'UN TEST GEOTHERMIQUE PEU PROFOND DANS UN AQUIFERE SABLEUX PAR TOMOGRAPHIE DE RESISTIVITE ELECTRIQUE : ETUDE DE FAISABILITE
Hermans, Thomas ULg; Vandenbohede, Alexander; Nguyen, Frédéric ULg et al

in Bulletin du groupe francophone d'humidimétrie et transferts en milieux poreux (2010, November 24), 56(Novembre 2010), 21-26

A shallow thermal test was monitored with electrical resistivity tomography (ERT). Heated water (48°C) was injected in a sandy aquifer (10°C). Laboratory measurements indicated a change of 2.1 %/°C of ... [more ▼]

A shallow thermal test was monitored with electrical resistivity tomography (ERT). Heated water (48°C) was injected in a sandy aquifer (10°C). Laboratory measurements indicated a change of 2.1 %/°C of water electrical conductivity for injection water. Due to this change, the plume of heated water was detected by geophysical imaging. In parallel, a hydrogeological flow and heat transport model was calibrated. Geophysics brought important information to calibrate this model and to show the heat exchange through the unsaturated zone. The comparison of the two models shows that ERT was able to retrieve the position and the temperature of the plume. However, a distortion occurs due to the smoothing of the solution during the regularized inversion process. This work demonstrates the ability of ERT to help quantifying parameters governing heat transport in the subsurface non-invasively and therefore studying and designing heat and storage experiments for shallow reservoirs. [less ▲]

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See detailAnalysis of fetal death in relation with increased fetal nuchal translucency thickness in the south of Vietnam
To, Hong ULg; Schaaps, Jean-Pierre ULg; Foidart, Jean-Michel ULg

in Asian Federation of Societies for Ultrasound in Medicine and Biology (2010, November 18)

Objectives: The aim of this study was to investigate the fetal deaths relation with an increased fetal nuchal translucency (NT) thickness in the South of Vietnam. Methods: A total of 2500 singleton ... [more ▼]

Objectives: The aim of this study was to investigate the fetal deaths relation with an increased fetal nuchal translucency (NT) thickness in the South of Vietnam. Methods: A total of 2500 singleton pregnancies were measured fetal NT thickness and performed free beta subunit of human Chorionic Gonadotropin (free β-hCG) and pregnancy associated plasma protein-A (PAPP-A) routinely in the first trimester, then scanned systematically for fetal structure by ultrasonography at the second trimester of gestation, next followed to their delivery and examined neonatal status. For suspicion of fetal abnormality, amniocentesis was indicated to confirm a fetal karyotype. Fetal abnormal chromosome was counselled a termination of pregnancy (TOP). 5 groups of fetal NT thickness was divided: group of normal fetal NT thickness (< 2.4mm), group of mild increased of fetal NT thickness (2.4-3.4mm), group of moderate increased fetal NT (3.5-4.4mm), group of severe fetal NT (4.5-5.4mm) and group of very severe fetal NT (≥ 5.5mm). We evaluated the fetal deaths (included spontaneous abortion, fetal death intra-uterine, and terminated pregnancy due to aneuploidy and/or structural abnormality), then look for a relation between an increased fetal NT thickness and those fetal adverse outcomes. Results: Fetal NT thickness cut-off point at 2.4mm or more was defined as an increased fetal NT thickness with 65.5% of sensitivity for fetal abnormal detection. 5.3% (133/2500) was the prevalence of increased fetal NT thickness. 2.8% (71/2500) of cases had been indicated an amniocentesis. A total incidence of fetal death was found 1.5% (37/2500). In group of fetal NT thickness < 2.4mm, the rate of abnormal karyotype was 0.4% (10/2367), none case of fetal deaths obtained. In the fetal NT group of 2.4-3.4mm, total of fetal death found 26.4% (32/121) that included 12.4% (15/121) of abnormal karyotype, 8.3% (10/121) of abnormal ultrasound scanning, 5.8% (7/121) of fetal demised, and 0.8% (1 case) of neonatal defect due to G6PD deficiency. In the group of 3.5-4.4mm, 33.3% (3/9) of fetuses were died (22.2% was due to aneuploidy and 11.1% was due to miscarriage spontaneously). In the group of 4.5-5.4mm, 1 case (50%) of trisomy 18 was detected and in the group of ≥ 5.5mm, 1 case (100%) of trisomy 21 had been diagnosed. When fetal NT thickness increased, the possibility of fetal demised was higher significantly: likelihood ratio (LR) augmented from 15.2 in the fetal NT group at 2.4-3.4mm to 169.5 in fetal NT group at ≥ 5.5mm (p < 0.01, Pearson chi2). Conclusion: An increased fetal NT thickness was useful finding for prediction of fetal deaths (included fetal abortion, demised or terminated) in the prenatal diagnosis and care program in the South of Vietnam. [less ▲]

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See detailMemantine-induced brain activation as a model for the rapid screening of potential novel antipsychotic compounds: Exemplified by an mGlu2/3 receptor agonist
Dedeurwaerdere, S.; Wintmolders, C.; Straetemans, R. et al

in Society-for-Neuroscience Abstracts/Annual Meeting Publications (2010, November 17), 40

Schizophrenia is a severe, disabling chronic disorder affecting approximately 1% of the population. Unfortunately, patients afflicted by this difficult to treat psychiatric illness remain stigmatized and ... [more ▼]

Schizophrenia is a severe, disabling chronic disorder affecting approximately 1% of the population. Unfortunately, patients afflicted by this difficult to treat psychiatric illness remain stigmatized and are likely to suffer permanent cognitive and social deficits. Improvements and development of more robust and hopefully predictive screening assays for this disease should enhance the identification and development of novel treatments. The present study describes a rapid and robust method for the testing of potential novel antipsychotics by utilising a simplified [14C]2-deoxyglucose (2-DG) uptake autoradiography technique following memantine-induced brain activation. Male C57BL/6JCRL mice were treated with either vehicle, ketamine (30 mg/kg, s.c.) or memantine (20 mg/kg, s.c.). Both NMDA antagonists induced significant increases in 2-DG uptake in specific brain region such as lateral orbital cortex, olfactory tubercle, piriform cortex, cingulate cortex, retrosplenial cortex, lacunosum molecular layer of the hippocampus and the lateral posterior thalamic nucleus. Interestingly, memantine elicited a more robust brain activation signature with a larger dynamic window than ketamine. For further characterisation of the assay, we also tested the effect of diet (fasting versus non-fasting) and different vehicles. In addition, dedicated software, developed particularly for this assay, was evaluated for automated quantification of the brain sections. In subsequent reversal studies, we found that in accordance to the ketamine challenge model (Duncan et al. 1998), the “atypical” anti-psychotic clozapine (2.5 and 10 mg/kg, s.c.) significantly reversed memantine-induced 2-DG uptake whilst the “typical” anti-psychotic haloperidol (0.32 mg/kg, s.c.) was inactive thus further validating our choice of memantine for the challenge agent. An additional study then determined the effects of a mGlu2/3 receptor agonist on both ketamine and memantine-induced brain activation. Pre-treatment with LY404039 (10 mg/kg, s.c.) fully reversed both the ketamine and memantine-induced increase in 2-DG uptake without effects on basal 2-DG uptake. Finally, a small animal PET study was performed with [18F]-FDG in mice and rats investigating the effect of memantine (20 mg/kg) administration in vivo. This study confirmed the memantine-induced brain activation previously demonstrated by autoradiography. In conclusion, this novel pre-clinical method shows potential for the screening of compounds targeting the NMDA receptor hypofunction hypothesis of schizophrenia and may assist in translating these findings from the bench to clinic. [less ▲]

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See detailApproches comparées de l'entrepreneuriat social en Europe et aux Etats-Unis
Defourny, Jacques ULg

in Revue Internationale de l'Economie Sociale : Recma, Revue des Etudes Coopératives, Mutualistes et Associatives (2010, November 09)

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See detailLiposomes loaded with diglyceride esters of methotrexate and mephalan studies on stability and hemocompatibility
Kuznetsova, N; Kandyba, A.K.; Bovin, N et al

in European Cells and Materials (2010, November 03), 20(3), 152

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See detailNew advances in asteroseismology of pulsating hot subdwarf stars
Charpinet, S.; Van Grootel, Valérie ULg; Randall, S. K. et al

in Highlights of Astronomy (2010, November 01), 15

Hot subdwarf stars (of the sdB and sdO type) host three known classes of nonradial pulsators. Two of them feature short period (P ~ 60 - 600 s) accoustic mode oscillations, while the third group is ... [more ▼]

Hot subdwarf stars (of the sdB and sdO type) host three known classes of nonradial pulsators. Two of them feature short period (P ~ 60 - 600 s) accoustic mode oscillations, while the third group is characterized by slow g-mode deformations with periods of ~ 1 - 2h. These pulsations offer favorable grounds to infer some of the internal properties of these objects through asteroseismology. This has been exploited for the rapid p-mode sdB pulsators and the present contribution reviews some of the recent advances in this field. The long period g-mode pulsators, whose vibrations probe much deeper inside the star, are also of high interest. With the advent of space observations using CoRoT and KEPLER, the asteroseismology of these slower oscillators will also become a possibility, and likely contribute to significant breakthroughs in our understanding of these hot and compact stars. [less ▲]

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See detailPhase 2 Results of XL184 in a Cohort of Patients with Advanced Melanoma
Nechushtan, Hovav; Edelman, Gerald; JERUSALEM, Guy ULg et al

in EJC Supplements (2010, November), 8(7), 126-127

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See detailAdding value to test-day data by using modified best prediction method
Gillon, Alain ULg; Abras, Sven; Mayeres, Patrick et al

in ICAR Technical Series (2010, November), 14

Computation of lactation yields from test-day data has lost much of its importance for genetic evaluations as the use of test-day models is currently quite widespread. In the other hand its interest for ... [more ▼]

Computation of lactation yields from test-day data has lost much of its importance for genetic evaluations as the use of test-day models is currently quite widespread. In the other hand its interest for intra-farm management is increasing as a base for advanced management tools. The first and principal aim of this study was to develop a method which takes into account advantages and disadvantages of existing methods, and to test its potential to provide useful management tools to dairy farmers. A test-day model with modifications to able daily run and management tools was developed. Because of its similarities with best prediction, the method developed here was called modified best prediction. The second objective was to compare the accuracy of this new method with best prediction and test interval methods. Modified best prediction showed good results for predicting daily yields and was slightly better than best prediction for lactation yields prediction. Management tools obtained with modified best prediction are explained. [less ▲]

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See detailNutritive value of fibrous ingredients fed to pigs in the Democratic Republic of Congo measured using an in vitro technique
Kambashi Mutiaka, Bienvenu ULg; Boudry, Christelle ULg; Picron, Pascale ULg et al

in Advances in Animal Biosciences (2010, November), 1(2), 423-424

Incorporation of forages in the diets can improve the economics of smallholder pig production in tropical countries. However, the information on the nutritive value of fibrous crop by-products and forages ... [more ▼]

Incorporation of forages in the diets can improve the economics of smallholder pig production in tropical countries. However, the information on the nutritive value of fibrous crop by-products and forages species used as ingredients in pig diets is scarce. The present work aimed at measuring the chemical composition and the nutritive value using an in vitro model of the pig gastro-intestinal tract of 21 ingredients used by farmers in the province of Bas-Congo (D.R. Congo). [less ▲]

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See detailTrend of hip fracture incidence in Belgium between 2000 and 2007 and future projections
Hiligsmann, Mickaël ULg; Bruyère, Olivier ULg; Detilleux, Johann ULg et al

in Value in Health (2010, November), 13(7), 303

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See detailEvaluation des peurs liées à la douleur du lombalgique chronique au moyen du PHODA (Photograph Series of Daily Activities)
Demoulin, Christophe ULg; Accary, Laure; Somville, Pierre-René ULg et al

in Revue du Rhumatisme (2010, November), 77(Supplément 3), 52-53

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See detailEvaluation du contenu du PHODA (Photograph Series of Daily Activities) par des spécialistes du rachis
Demoulin, Christophe ULg; Accary, Laure; Somville, Pierre-René ULg et al

in Revue du Rhumatisme (2010, November), 77(Supplément 3), 52

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See detailPour en finir avec la génération Y. Enquête sur une représentation managériale
Pichault, François ULg; Pleyers, Mathieu

in Actes des Congrès de l'AGRH (2010, November)

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See detailLe ranélate de strontium augmente la viabilité de chondrocytes humains stimulés par IL-1 bêta
Merville, Marie-Paule ULg; Deroyer, Céline ULg; Bruyère, Olivier ULg et al

in Revue du Rhumatisme (2010, November), 77(Suppl.3), 222

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See detailRanélate de strontium : efficacité à long terme sur 10 ans chez les femmes ménopausées ostéoporotiques
Reginster, Jean-Yves ULg; Kaufman, Jean-Marc; Goemaere, S. et al

in Revue du Rhumatisme (2010, November), 77(Suppl.3), 99-100

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See detailEvolution des structures de sols sous itinéraires techniques contrastés : relations entre courbes de rétention et analyse par microtomographie à rayons X
Beckers, Eléonore ULg; Roisin, Christian; Léonard, Angélique ULg et al

in Milieux Poreux et Transferts Hydriques (2010, November), 56

Tillage reduction seems to affect porosity distribution, orientation and connectivity. Soil samples were removed from plots under conventional tillage or reduced tillage. Their water retention curves were ... [more ▼]

Tillage reduction seems to affect porosity distribution, orientation and connectivity. Soil samples were removed from plots under conventional tillage or reduced tillage. Their water retention curves were measured, and the characterization of soils porosity was made using x-ray microtomography measurements. Results show differences in the meso as well as in the macroporosity. [less ▲]

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See detailCan an underestimation of opacity explain B-type pulsators in the SMC?
Salmon, Sébastien ULg; Montalban Iglesias, Josefa ULg; Miglio, Andrea ULg et al

in Astronomische Nachrichten (2010, October 09), 331(9-10),

Slowly Pulsating B and ß Cephei are ĸ mechanism driven pulsating B stars. That ĸ mechanism works since a peak in the opacity due to a high number of atomic transitions from iron-group elements occurs in ... [more ▼]

Slowly Pulsating B and ß Cephei are ĸ mechanism driven pulsating B stars. That ĸ mechanism works since a peak in the opacity due to a high number of atomic transitions from iron-group elements occurs in the area of log T ~ 5.3. Theoretical results predict very few SPBs and no ß Cep to be encountered in low metallicity environments such as the Small Magellanic Cloud. However recent variability surveys of B stars in the SMC reported the detection of a significant number of SPB and ß Cep candidates. Though the iron content plays a major role in the excitation of ß Cep and SPB pulsations, the chemical mixture representative of the SMC B stars such as recently derived does not leave room for a significant increase of the iron abundance in these stars. Whilst abundance of iron-group elements seems reliable, is the opacity in the iron-group elements bump underestimated? We determine how the opacity profile in B-type stars should change to excite SPB and ß Cep pulsations in early-type stars of the SMC. [less ▲]

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See detailThe PLATO End-to-End CCD Simulator -- Modelling space-based ultra-high precision CCD photometry for the assessment study of the PLATO Mission
Zima, W.; Arentoft, T.; De Ridder, J. et al

in Astronomische Nachrichten (2010, October 09), 331(9-10),

The PLATO satellite mission project is a next generation ESA Cosmic Vision satellite project dedicated to the detection of exo-planets and to asteroseismology of their host-stars using ultra-high ... [more ▼]

The PLATO satellite mission project is a next generation ESA Cosmic Vision satellite project dedicated to the detection of exo-planets and to asteroseismology of their host-stars using ultra-high precision photometry. The main goal of the PLATO mission is to provide a full statistical analysis of exo-planetary systems around stars that are bright and close enough for detailed follow-up studies. Many aspects concerning the design trade-off of a space-based instrument and its performance can best be tackled through realistic simulations of the expected observations. The complex interplay of various noise sources in the course of the observations made such simulations an indispensable part of the assessment study of the PLATO Payload Consortium. We created an end-to-end CCD simulation software-tool, dubbed PLATOSim, which simulates photometric time-series of CCD images by including realistic models of the CCD and its electronics, the telescope optics, the stellar field, the pointing uncertainty of the satellite (or Attitude Control System [ACS] jitter), and all important natural noise sources. The main questions that were addressed with this simulator were the noise properties of different photometric algorithms, the selection of the optical design, the allowable jitter amplitude, and the expected noise budget of light-curves as a function of the stellar magnitude for different parameter conditions. The results of our simulations showed that the proposed multi-telescope concept of PLATO can fulfil the defined scientific goal of measuring more than 20000 cool dwarfs brighter than mV =11 with a precision better than 27 ppm/h which is essential for the study of earth-like exo-planetary systems using the transit method. [less ▲]

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See detailOPRs of Ammonia versus 14N/15N Ratios in CN in 15 Comets
Shinnaka, Yoshiharu; Kawakita, H.; Kobayashi, H. et al

in Bulletin of the American Astronomical Society (2010, October 01), 42

The solar system was formed from interstellar matter 4.6 Gyrs ago and comets are considered as remnants of icy planetesimals formed in the early solar system. One of interesting primordial characters of ... [more ▼]

The solar system was formed from interstellar matter 4.6 Gyrs ago and comets are considered as remnants of icy planetesimals formed in the early solar system. One of interesting primordial characters of cometary ice is an ortho-to-para abundance ratio (OPR) of molecules such as H2O, NH3, etc. The OPR probably indicates the molecular formation temperatures in the solar nebula or in the pre-solar molecular cloud. We determined the OPRs of ammonia by using the high dispersion optical spectra of NH2 in 15 comets: C/1995 O1 (Hale-Bopp), C/1999 S4 (LINEAR), C/2001 A2 (LINEAR), C/2000 WM1 (LINEAR), 153P/Ikeya-Zhang, C/2002 V1 (NEAT), C/2002 X5 (Kudo-Fujikawa), C/2002 Y1 (Juels-Holvorcem), C/2001 Q4 (NEAT), C/2002 T7 (LINEAR), C/2003 K4 (LINEAR), 8P/Tuttle, 88P/Howell, 9P/Tempel 1, and 73P-B and -C/Schwassmann-Wachmann 3. The observations were mainly carried out by the Ultraviolet and Visual Echelle Spectrograph (UVES) mounted on the Very Large Telescope (VLT) in Chile. Other telescopes/instruments were also used in some cases. The OPRs of ammonia are determined from OPRs of NH2 (0,9,0) ro-vibronic band around 600 nm. Although absorption lines (by the telluric atmosphere) and cometary C2 emission lines blended affected to NH2 emission lines in this region, we removed them in our analysis. The determined OPRs of ammonia clustered around 30K but not in the cases of 73P-B and -C. This situation is very similar to that of 14N/15N ratios in CN (i.e., 73P-B and -C are quite peculiar relative to other comets). We discuss about the relationship between the OPRs of ammonia and 14N/15N ratios in CN in these 15 comets. Our results indicate the formation of materials at relatively higher temperatures for 73P-B and -C than other comets. [less ▲]

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See detailThe 3/4 July 2010 Pluto Stellar-Occultation Observations
Pasachoff, Jay M; Elliot, J. L.; Souza, S. P. et al

in Bulletin of the American Astronomical Society (2010, October 01), 42

Continuing our monitoring of Pluto's atmospheric temperature and pressure, previously shown by us to be increasing (Elliot et al., Nature 424, 165, 2003; Pasachoff et al., AJ 129, 1718, 2005) and ... [more ▼]

Continuing our monitoring of Pluto's atmospheric temperature and pressure, previously shown by us to be increasing (Elliot et al., Nature 424, 165, 2003; Pasachoff et al., AJ 129, 1718, 2005) and subsequently found by us to be leveling off (Elliot et al., AJ 134, 1, 2007), we report on a stellar occultation by Pluto of UCAC2 mag=15.3, observed from South America and Africa on 4 July 2010 UT. Success was achieved with a 0.45 m at Cerro Calan using one of our POETS (Portable Occultation, Eclipse, and Transit System; Souza et al. PASP 118, 1550, 2006), a 1.0 SMARTS (Small and Medium Aperture Research Telescope System) at Cerro Tololo, four 0.6 m telescopes of PROMPT (Panchromatic Robotic Optical Monitoring and Polarimetry Telescopes) on Cerro Tololo, and TRAPPIST's (TRansiting Planets and Planetesimals Small Telescope) 0.6-m telescope on La Silla in Chile; the 0.35 m telescope of U. Ponta Grossa, Brazil; and the 0.75-m ATOM (Automatic Telescope for Optical Monitoring), Namibia, using POETS. Winds prevented opening the 6.5 m Magellan/Clay telescope on Las Campanas, Chile, with its own frame-transfer camera, and clouds obscured the 1.9 m telescope at Sutherland, South Africa, which had POETS. With shadow velocity 23.6 km/s, it was a rapid event: maximum occultation <2 minutes. The observations were supported in part by grants NNX08AO50G to Williams College and NNX10AB27G to MIT from NASA's Planetary Astronomy Division, and NNH08AI17I to USNO for astrometry. Student participation was supported in part by NASA's Massachusetts Space Grant and NSF's REU. Japan's government donated U. Chile's Cerro Calan Goto telescope. PROMPT observations were made possible by the Robert Martin Ayers Science Fund. TRAPPIST is a project driven by the University of Liège, in close collaboration with the Observatory of Geneva, supported by the Belgian Fund for Scientific Research and the Swiss National Science Foundation. [less ▲]

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See detailComet 29P/Schwassmann-Wachmann Observed with the Herschel Space Observatory: Detection of Water Vapour and Dust Far-IR Thermal Emission
Bockelee-Morvan, Dominique; Biver, N.; Crovisier, J. et al

in Bulletin of the American Astronomical Society (2010, October 01), 42

The distant comet 29P/Schwassmann-Wachmann was observed with the HIFI, PACS and SPIRE instruments aboard the Herschel Space Observatory, as part of the guaranteed time key programme "Water and related ... [more ▼]

The distant comet 29P/Schwassmann-Wachmann was observed with the HIFI, PACS and SPIRE instruments aboard the Herschel Space Observatory, as part of the guaranteed time key programme "Water and related chemistry in the Solar System" (KP-GT HssO). Supporting observations of the 230 GHz CO line were carried out with the IRAM 30-m telescope. The HIFI observations of the 557 GHz H2O line were performed on 19.05 April 2010, about 2 days after a major outburst, and on 11.02 May 2010, when 29P was in a more quiescent phase. H2O was detected on both dates with a production rate corresponding to about 1/10th the CO production, assuming near-nucleus production. The H2O line shape is consistent with release of water vapour from icy grains. PACS and SPIRE imaging data from 70 to 500 micrometers were acquired mid-June 2010 when the comet was in a quiescent phase. The continuum emission detected in the 70-μm and 160-μm PACS images is weakly extended with respect to the PSF, suggesting a major contribution from the nucleus or from slowly moving large grains. [less ▲]

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See detailAdvantages, disadvantages and feasibility of Pay-for-Quality programs in Belgium
Van Herck, Pieter; Sermeus, Walter; Annemans, Lieven et al

in BMC Health Services Research (2010, October), 10

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See detailProgress in the asteroseismic analysis of the pulsating sdB star PG 1605+072
Van Grootel, Valérie ULg; Charpinet, Stéphane; Fontaine, Gilles et al

in Astrophysics & Space Science (2010, October), 329

The hot pulsating sdB star PG 1605+072 exhibits uncommon spectroscopic and pulsation properties, and is one of the biggest challenge in the field of sdB star modeling. Two hypotheses have been proposed to ... [more ▼]

The hot pulsating sdB star PG 1605+072 exhibits uncommon spectroscopic and pulsation properties, and is one of the biggest challenge in the field of sdB star modeling. Two hypotheses have been proposed to explain its unusually rich pulsation spectrum. The first is the natural explanation of a fast-rotating pulsator, which lifts the (2 l+1)-fold degeneracy of the frequency components. Another approach, where PG 1605+072 can be seen as a slow rotator, considers that the numerous low amplitude frequency components are second- and third-order harmonics and nonlinear combinations of the highest amplitude frequencies. We investigated the two hypotheses in the light of asteroseismology, using our latest tools—including pulsation codes that incorporate star rotation and new generation complete sdB models. The results of both approaches are presented, showing interesting results and raising new questions for our understanding of this mysterious sdB star. [less ▲]

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See detailBiocompatible solid particles for controlled instigation of cavitation during therapeutic ultrasound.
Arora, Manish; Schiffter, Heiko; Manhas, Varun ULg et al

in Journal of the Acoustical Society of America (2010, October), 128(4), 2440

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See detailSynovium angiogenesis in osteoarthritis: a new therapy target for chondroitin sulfate
Mathy, Marianne ULg; Lambert, Cécile ULg; Dubuc, Jean Emile et al

in Osteoarthritis and Cartilage (2010, October), 18

Purpose: Osteoarthritis (OA) is an important cause of pain and disability in the ageing population. Angiogenesis and inflammation are closely integrated process in OA and may contribute to its ... [more ▼]

Purpose: Osteoarthritis (OA) is an important cause of pain and disability in the ageing population. Angiogenesis and inflammation are closely integrated process in OA and may contribute to its pathogenesis, as well as, affect disease progression and pain. Chondroitin sulfate (CS) is a symptomatic slow acting drug for OA and there is strong evidence suggesting that CS may also be a structure disease modifying osteoarthritis drug. The mechanisms underlying these effects remain poorly understood. This work aimed to demonstrate the relation between inflammation and angiogenesis of synovium and to study the effect of CS on synovium angiogenesis. [less ▲]

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See detailThe impact of HAART initiation on the selection and persistence of HIV-1 CTL-escape mutations
Dilernia, D.A.; Monaco, D.C.; Jones, L.R. et al

in AIDS Research and Human Retroviruses (2010, October), 26(10), 72

The impact of HAART initiation on the selection and persistence of HIV-1 CTL-escape mutations D.A. Dilernia,1 D.C. Monaco,1 L.R. Jones,2 G.D. Damilano,1 S. Rodriguez,3 H. Salomon1 1Argentinean Reference ... [more ▼]

The impact of HAART initiation on the selection and persistence of HIV-1 CTL-escape mutations D.A. Dilernia,1 D.C. Monaco,1 L.R. Jones,2 G.D. Damilano,1 S. Rodriguez,3 H. Salomon1 1Argentinean Reference Center for AIDS, Capital Federal, Argentina; 2División de Biología Molecular, Estación de Fotobiología, Playa Unión, Rawson, Chubut, Argentina; 3INTA, Castelar, Buenos Aires, Argentina Background: Immune response drives the selection of CTL escape mutations during the course of HIV infection. After initiation of HAART, antiviral drugs exert a strong selective force leading to an important limitation of viral replication. Our objective was to evaluate the impact of HAART initiation on the selection and persistence of CTL-escape mutations. Methods: Blood samples were collected from 113 newly HIV diagnosed individuals. A second sample was collected from 49 of them after 3 years. (12 of which were still drug-naı¨ve in the second sample). Dynamics of CTL-escape mutations identified in the gag gene by statistical analysis of HLA genes and viral sequences, including multiple comparison corrections (BH method) and phylogeny correction (Bayesian MCM method), were analyzed. Epitope-specific immune response was evaluated by ELISPOT against sequence-based designed peptides. Results: Immune response was evaluated on 113 individuals on an HLA-allele basis. Positive responses were detected against 6 of the 9 epitopes containing HLA-associated CTL-escape mutations.A03-restricted epitope RLRPGGKKK had the highest frequency of detection in allele-matched individuals (75%). Epitopes harboring the CTL-escape mutations identified through negative associations (i.e. escape is consensus) had lower frequency of detection: A02-restricted SLYNTVATL(25%) and A24-resctricted KYKLKHIVW(0%). Epitope sequences analysis over the second sample of 21 patients successfully sequenced showed that 38% of them did not have evidence of escape neither in the first sample nor in the second, 44% had the escape mutations in both samples and in 18%the escape mutations appeared in the second sample. Of the 7 individuals containing the epitopes of the last group, only 2 had initiated HAART (28.6%) while 64.3% (9/14) of individuals where no escape emerged, had initiated HAART. Conclusion: Accumulation of CTL-escape mutations at the population-level impaired recognition by individuals studied while initiation of HAART may prevent the selection of new escape mutations even in advanced stages of infection. [less ▲]

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See detailEXOTIME: searching for planets around pulsating subdwarf B stars
Schuh, Sonja; Silvotti, Roberto; Lutz, Ronny et al

in Astrophysics & Space Science (2010, October), 329

In 2007, a companion with planetary mass was found around the pulsating subdwarf B star V391 Pegasi with the timing method, indicating that a previously undis- covered population of substellar companions ... [more ▼]

In 2007, a companion with planetary mass was found around the pulsating subdwarf B star V391 Pegasi with the timing method, indicating that a previously undis- covered population of substellar companions to apparently single subdwarf B stars might exist. Following this serendip- itous discovery, the EXOTIME (http://www.na.astro.it/ ~silvotti/exotime/) monitoring program has been set up to follow the pulsations of a number of selected rapidly pul- sating subdwarf B stars on time scales of several years with two immediate observational goals: (1) determine P ̇ of the pulsational periods P (2) search for signatures of substellar companions in O– C residuals due to periodic light travel time variations, which would be tracking the central star’s companion- induced wobble around the centre of mass These sets of data should therefore, at the same time, on the one hand be useful to provide extra constraints for classical asteroseismological exercises from the P ̇ (comparison with “local” evolutionary models), and on the other hand allow one to investigate the preceding evolution of a target in terms of possible “binary” evolution by extending the otherwise unsuccessful search for companions to potentially very low masses. While timing pulsations may be an observationally ex- pensive method to search for companions, it samples a dif- ferent range of orbital parameters, inaccessible through or- bital photometric effects or the radial velocity method: the latter favours massive close-in companions, whereas the timing method becomes increasingly more sensitive toward wider separations. In this paper we report on the status of the on-going ob- servations and coherence analysis for two of the currently five targets, revealing very well-behaved pulsational charac- teristics in HS 0444+0458, while showing HS 0702+6043 to be more complex than previously thought. [less ▲]

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See detailAn integrated history of paleoearthquakes along the North Anatolian Fault (Turkey)
Hubert, Aurelia ULg; Vanneste, Kriss; Avsar, U.

in Abstracts with Programs - Geological Society of America (2010, October)

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See detailSedimentological fingerprints of paleoseimic activity revealed from lake sediments: a case study from the North Anatolian Fault (NAF), Turkey
Avsar, Ulas; Hubert, Aurelia ULg; Fagel, Nathalie ULg et al

in Abstracts with Programs - Geological Society of America (2010, October)

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See detailLong-term evolution of the North Anatolian Fault
Hubert, Aurelia ULg; Van Der Woerd, Jerome; King, G. et al

in Abstracts with Programs - Geological Society of America (2010, October)

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See detailEffectiveness of zoledronic acid in the prevention and treatment of glucocorticoid-induced osteoporosis in men and premenopausal women
Saag, k; Roux, C.; Devogelaer, J. P. et al

in Arthritis and Rheumatism (2010, October), 62(10), 902-903

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See detailLong-term denosumab treatment of postmenopausal women with osteoporosis: results from the first year extension study of the FREEDOM trial
Chapurlat, R.; Papapoulos, Socrates; Bone, Henry G et al

in Arthritis and Rheumatism (2010, October), 62(10), 903

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See detailRelationship between changes in bone mineral density or bone turnover markers and vertebral fracture incidence in patients treated with bazedoxifene
Bruyère, Olivier ULg; Detilleux, Johann ULg; Akadi, Chines et al

in Arthritis and Rheumatism (2010, October), 62(10), 406-407

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See detailComparaison de l'évaluation des propriétés de transport tranpéritonéal au moyen d'un dialysat "conventionnel" par rapport à un nouveau dialysat dit "biocompatible"
Van Overmeire, Lionel ULg; Goffin, E.; Bovy, Philippe et al

in Néphrologie & Thérapeutique (2010, September 30), 6

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See detailEvolution nutritionnelle des patients hémodialysés du CHBAH
Meurice, C.; Smelten, Nicole; Furnemont, L. et al

in Néphrologie & Thérapeutique (2010, September 28), (6), 393-394

La dénutrition touche les patients en hémodialyse surtout lorsqu'ils ont plus de 50 ans et plus de 5 ans de dialyse. En 2006, nous avions observé que les patients dialysés (n = 27) ne consommaient pas le ... [more ▼]

La dénutrition touche les patients en hémodialyse surtout lorsqu'ils ont plus de 50 ans et plus de 5 ans de dialyse. En 2006, nous avions observé que les patients dialysés (n = 27) ne consommaient pas le taux de protéines et de calories recommandé. Depuis, nous avons élargi nos régimes. Cette présente étude évalue l'impact de cette nouvelle attitude nutritionnelle chez les anciens (n=11) et les nouveaux patient (n=10). [less ▲]

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See detailCould Western blot analysis be an alternative to radio-immunoassay for sheep pregnancy associated glycoproteins measurements ?
El Amiri, B.; El Abbadi, N.; Benjelloun, B. et al

in Reproduction in Domestic Animals (2010, September 15), 45(Suppl 3), 65

This study prospected whether Western blot analysis could be an alternative to radio-immunoassay (RIA) for sheep pregnancy diagnosis. Blood samples were taken from Boujaâd ewes (n= 9) and Boujaâd x D’man ... [more ▼]

This study prospected whether Western blot analysis could be an alternative to radio-immunoassay (RIA) for sheep pregnancy diagnosis. Blood samples were taken from Boujaâd ewes (n= 9) and Boujaâd x D’man (BD) cross breed (n= 12). The pregnancy associated glycoproeins (PAGs) were weekly monitored in plasma during the whole gestation and the first month postpartum by two RIA systems (El Amiri et al., 2007, Reprod Domest Anim 42:257-62). The highly immunoreactive samples derived from PAG profiles were tested using Western blot based on the same antiserum used in RIA. Each week (from the 13th to the 19th week), two pools of plasma samples (4 ml each) were taken from single and multiple lambing ewes respectively. Samples were submitted to a protein extraction at neutral pH, followed by ammonium sulfate (A.S.) precipitation, dialysis, and lyophilization. The placental extract was used as a check. Results revealed that ewes with multiple lambs presented numerically higher PAG concentrations. In both RIA systems, the high concentrations were recoded around the 19th week of gestation and the maximal concentrations varied from 120 to 700 ng/ml. In Western blot, the placental extracts reacted positively while the plasma samples did not give any positive reaction. In conclusion, the RIA remains the only sensitive method to measure PAGs in plasma. The present study strengthens the need to develop an ELISA kit as an alternative to RIA systems. [less ▲]

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See detailLes conceptions de l'entreprise sociale en Europe et aux Etats-Unis: convergences et divergences
Defourny, Jacques ULg; Nyssens, Marthe

in Revue Internationale de l'Economie Sociale : Recma, Revue des Etudes Coopératives, Mutualistes et Associatives (2010, September 09), 319(janvier 2011), 18-35

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See detailDosage de la 25-OH vitamine D: attention aux erreurs analytiques!
Cavalier, Etienne ULg; Carlisi, Ignazia ULg; Delanaye, Pierre ULg et al

in 27ème Congrès de la Société Française d'Endocrinologie - Deauville, 29 septembre - 2 octobre 2010 (2010, September)

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