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See detailLe Système Local de Santé (SYLOS) en 2014 : une approche de la concertation entre lignes de soins à l’échelon local par la recherche-action.
Belche, Jean ULg; Duchesnes, Christiane ULg; van der Vennet, Jean et al

in Revue Médicale de Bruxelles (2014, May), 35(n°3), 1-20

Le vieillissement de la population et la multi-morbidité, la volonté de rationalisation des dépenses dans les soins de santé remettent à l’avant-plan la nécessité d’une articulation plus importante entre ... [more ▼]

Le vieillissement de la population et la multi-morbidité, la volonté de rationalisation des dépenses dans les soins de santé remettent à l’avant-plan la nécessité d’une articulation plus importante entre les deux lignes de soins. Alors qu’une approche intégrée et centrée sur le patient et la communauté est souhaitable, la collaboration prend actuellement la forme d’initiatives nationales ou locales, centrées sur une pathologie. L’objectif de l’étude est d’analyser les différentes modalités de concertation entre les acteurs de la 1ère ligne de soins et de la 2ème ligne de soins au niveau local et éventuellement d’en encourager de nouvelles. Le projet SYLOS Liège est une recherche-action initiée par le Département de Médecine Générale de l’Université de Liège et le Département de Santé Publique de l’Institut de Médecine Tropicale d’Anvers. Trois zones d’étude ont été définies en région liégeoise. Des rencontres individuelles de sensibilisation ont été menées pour présenter le projet et recueillir les premières réactions des protagonistes par rapport à la thématique. Des entretiens semi-dirigés ont ensuite été menés avec certains répondants intéressés pour évoquer les initiatives de concertation existantes, les difficultés et avantages perçus. Finalement, des rencontres mixtes ont été proposées aux acteurs de terrain. Trois ans après le début du projet, il est possible d’identifier les freins et les opportunités actuels à la mise en place de ce type de concertation. Le processus a permis de faire émerger, sur une des trois zones étudiées, une dynamique de réflexion et de recherche de solutions par la concertation entre professionnels concernés. La progression différente sur les trois zones montre l’importance de la prise en compte de l’échelon local. D’un point de vue méthodologique, il apparaît également que la recherche-action et sa visée praxéologique est adaptée à cette problématique. [less ▲]

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See detailEccentric training for elbow hypermobility
Kaux, Jean-François ULg; Delvaux, François ULg; Forthomme, Bénédicte ULg et al

in British Journal of Sports Medicine (2014, April), 48(7), 154

Background: Patients with hypermobility suffer from joints problems and chronic pain is the most frequently reported symptom. Objective: Eccentric muscle strengthening could be very important to protect ... [more ▼]

Background: Patients with hypermobility suffer from joints problems and chronic pain is the most frequently reported symptom. Objective: Eccentric muscle strengthening could be very important to protect hypermobile joints. Design: Case report. Patient: A girl (16 y.o.) affected by an Ehler-Danlos syndrome presented pain in the right elbow and the right wrist after a season of tennis. Interventions: Her training consisted of wrist prono-supination and flexion-extension muscle group reinforcement and proprioceptive training. To protect the wrist against excessive load, the eccentric strengthening exercises of prono-supinator and flexor-extensor muscles of elbow and wrist were undertaken gradually, at increasing speeds within a limited range of motion in flexion and extension, on an isokinetic device after an evaluation. She was also given an orthesis restricting the joint range of motion of the wrist. Main outcome measurements: The evaluation was made by isokinetic evaluation, visual analog scale and MOS-SF36 questionnaire before and after training. Results: The patient rapidly noted a decrease in pain and an increase in the stability of her right arm even when playing tennis. Isokinetic evaluation objectified a significant improvement in maximal torque in flexion-extension muscles of the right elbow. She was also given individualized home exercises. Conclusions: The goal of this eccentric training is to avoid hypermobility by using the muscles as a protective brake in the control of joint positioning. Muscles can be reinforced in eccentric mode with starting position at the maximum length of these muscles when unstreched. The exercises can be carried out safely on an isokinetic device, at slow speed and limited range of joint motion to avoid risk of luxation. Thus, in this case report, the eccentric exercises using an isokinetic device were effective to safely reinforce the muscles as a protective brake for joint hypermobility and prevent pain during practicing tennis. [less ▲]

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See detailLa discussion à visée démocratique et philosophique au prisme de la critique deleuzienne de la discussion. Analyse d'un verbatim.
Herla, Anne ULg; Jeanmart, Gaëlle

in Diotime. Revue internationale de didactique de la philosophie (2014, April), 60

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See detailMultitasking capacities in persons diagnosed with schizophrenia: A preliminary examination of their neurocognitive underpinnings and ability to predict real world functioning
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Levaux, Marie-Noëlle ULg et al

in Schizophrenia Research (2014, April), 153(Supl. 1), 344

Background: Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia. Moreover, patients seem to demonstrate particular difficulties during complex and ... [more ▼]

Background: Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia. Moreover, patients seem to demonstrate particular difficulties during complex and multitasking activities, such as cooking a meal (Semkovska et al., 2004). Multitasking refers to activities where the person has to: carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; define the tasks’ targets; and where the person is faced with unexpected problems during the realization of these tasks (Burgess, 2000). However, at present, patients’ multitasking capacities have not been adequately examined in the literature due to an absence of suitable assessment strategies. We thus recently developed a computerized real-life activity task designed to take into account the complex and multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting – the Computerized Meeting Preparation Task (CMPT) Methods: Twenty-one individuals diagnosed with schizophrenia and 20 matched healthy controls completed the CMPT. During the CMPT, participants found themselves in a virtual room that they had to prepare for a meeting while respecting a list of instructions (the placement of the guests, the needed objects, the desired drinks, etc.). Patients were also evaluated with an extensive cognitive battery (assessing executive functions, attention, processing speed and memory), measures of symptomatology and real world functioning. To examine the ecological validity of the CMPT, 14 others patients were recruited and were given the computerized version and a real version of the meeting preparation task. Results: Results demonstrated that performance on the CMPT significantly differentiated patients and healthy controls for the total time to complete task, planning efficiency, and the respect of the instructions. Moreover, these variables were significantly correlated with executive functioning (i.e. cognitive flexibility and planning), suggesting the major implication of these cognitive processes in multitasking activities. Performance on the CMPT also significantly predicted up to 50% of real world functioning. Finally, performances on the computerized version and the real version of the meeting preparation task were highly correlated, suggesting good ecological validity. Discussion: In this study, we created a novel task involving the multitasking nature of real world activities. The results demonstrated that this approach provides a good indication of the real world functioning in patients diagnosed with schizophrenia. Moreover, results suggest a particular implication of executive functioning in multitasking activities. These findings suggest the importance of evaluating multitasking capacities in patients diagnosed with schizophrenia in order to predict real world functioning. [less ▲]

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See detailEccentric training improves tendon biomechanical properties: a rat model
Kaux, Jean-François ULg; Drion, Pierre ULg; Libertiaux, Vincent et al

in British Journal of Sports Medicine (2014, April), 48(7), 155

Background: Even if eccentric exercises appear favourable in primary prevention of tendons lesions and, especially, in secondary prevention after tendinopathy, the biomechanical changes to the tissue are ... [more ▼]

Background: Even if eccentric exercises appear favourable in primary prevention of tendons lesions and, especially, in secondary prevention after tendinopathy, the biomechanical changes to the tissue are not yet clear. Objective: We aimed to better define the biomechanical changes that affect healthy tendon after eccentric and concentric training. Design: Randomised controlled trial. Participants: Eighteen Sprague-Dawley rats of 2 months. Interventions: The six rats in the control group (U) were not subjected to physical exercise. The 12 remaining rats (6 in each group) ran on a treadmill set at a +15° incline for concentric training (C) or a -15° incline for eccentric training (E), at a speed of 17 m/min for 1 h, three times per week for 5 weeks. Main Outcome Measurements: The tricipital, patellar and Achilles tendons were subsequently removed to perform a traction test until rupture, and a histological analysis was performed. Results: There was a significant improvement in the rupture force of the patellar and tricipital tendons between the U and E groups. The tricipital tendons in the control group presented a significantly smaller cross-section than the E- and C-trained groups, but none between E and C groups. No significant difference was observed for the mechanical stress at rupture per surface unit between the three groups for all three tendons. However, a tendency towards improvement these values was observed between the trained and the U groups for the patellar tendon. Histological studies demonstrated the tendency of the development of a greater number of blood vessels and a larger quantity of collagen in the eccentric group. Conclusions: The mechanical properties of tendons in rats improve after specific training, especially following eccentric training. Our results partly explained how mechanical loading, especially in eccentric mode, could improve the tendon structure. [less ▲]

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See detailTwo biomarkers for the screening of cardiac risk among runners ?
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Fillet, Marianne ULg et al

in British Journal of Sports Medicine (2014, April), 48(7), 174

Background Heart-type fatty acid-binding protein (H-FABP) is a low molecular weight protein involved in the intracellular uptake and buffering of long chain fatty in the myocardium. Troponin T is a ... [more ▼]

Background Heart-type fatty acid-binding protein (H-FABP) is a low molecular weight protein involved in the intracellular uptake and buffering of long chain fatty in the myocardium. Troponin T is a component of the contractile apparatus of the striated musculature. Both are early markers for acute coronary syndrome. Objective The aim of our study was to compare the results obtained with the H-FABP and the highly sensitive cardiac troponins (hsTnT) and to test their cardiospecificity in healthy runners. Design Prospective, cohort study. Setting Amateur marathon runners. Patients 23 runners (marathon) were enrolled. Interventions We drowned blood samples at three times: just before (T0), just after (T1), and three hours after the end of the race (T3). Main outcome measurements H-FABP and hs-TnT were performed according to the manufacturer's instructions. A linear regression was calculated to observe if there is any correlation between the two biomarkers. Values above the 95th percentile for H-FABP (2.5 ng/mL) and the 99th percentile for hsTnT (14 ng/L) were considered as positive. Results At T0, none of the subjects were positive for hsTnT but 35% were positive for H-FABP; at T1, 83% for hsTnT and 100% for H-FABP; at T3, 83% for hsTnT and 96% for H-FABP. At T0, the regression equation was H-FABP T0=3.9454–0.1001×hsTnT T0; at T1: H-FABP T1=51.838–1.7026×hsTnT T1; at T3: H-FABP T3=47.977–1.6193×hsTnT T3. No correlation was observed between the 2 biomarkers. Conclusion We observed a significant increase of H-FABP and hsTnT in runners. These markers are independent to each other. These values could biologically correspond to a heart ischemia. These biomarkers could be helpful for the screening of cardiac risk among runners. [less ▲]

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See detailCardiac troponins and natriuretic peptides in runners: useful for cardiac risk screening ?
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Fillet, Marianne ULg et al

in British Journal of Sports Medicine (2014, April), 48(7), 173

Background Cardiac troponins (cTn) are considered as the best biomarkers for detection of myocardial cell injury and NT-proBNP as the best for the cardiac insufficiency. Objective Our aim was to compare ... [more ▼]

Background Cardiac troponins (cTn) are considered as the best biomarkers for detection of myocardial cell injury and NT-proBNP as the best for the cardiac insufficiency. Objective Our aim was to compare cTnT and NT-proBNP levels before and after the stress tests, in sportive subjects. Design Prospective, cohort study. Setting Amateur marathon runners and ultrarunners. Patients 28 subjects (26 men, 42.5±11 yrs) were enrolled. Interventions Subjects ran the Maasmarathon (42.195 kilometers) and 33 subjects (33 men, 45.7±9.3 yrs) ran the Ultratour of Liège (Belgium; 67 km). All subjects gave their informed consent. We took blood sample before (T0), just after (T1) and 3 hours after the race (T3). Main outcome measurements cTnT concentrations were measured by high sensitive methods (hsTnT, Roche Diagnostics) on heparin plasma. The NT-proBNP was also determined with the kit Roche on heparin plasma. All statistical analyses were performed using Medcalc version 8.1 for Windows. P-value <.01 was regarded as statistically significant. Results A significant difference between hsTnT concentrations at T0 and T1 (P<.001), and between T0 and T3 (P<.001) for NT-proBNP have been observed, but not between T1 and T3. This observation appeared only after a strenuous exercise. However, up to now this type of exercise is not reproducible easily in a laboratory. Moreover, nobody knows if these observations would have cardiac consequences at long terms. Conclusion Measurement of cardiac troponins by high sensitive methods allows detecting significant release of biomarkers from the heart during exercise. The value of NT-proBNP are also significant but less than TnThs. We think that the TnThs could be an interesting tool in the future to help sport medicine to detect risk of developing a cardiac problem in the future or a sudden death. [less ▲]

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See detailTGF-B induced protein IG-H3 is essential for the growth of human liver metastases
Castronovo, Vincenzo ULg; Blomme, Arnaud; Delvenne, Philippe ULg et al

in Acta Gastro-Enterologica Belgica (2014, March), 77(1), 05

Introduction : Transforming growth factor-beta-induced protein ig-h3 (TGFBI) is extracellular matrix component known to be important for cell-collagen interaction. We and others have reported elevated ... [more ▼]

Introduction : Transforming growth factor-beta-induced protein ig-h3 (TGFBI) is extracellular matrix component known to be important for cell-collagen interaction. We and others have reported elevated expression of TGFBI in sev- eral human cancers, where its role remains controversial. Aim Current study aims at clarifying the function of TGFBI to date. Methods &Results : CRC-LM and in liver metastases originating from breast, lung and pancreatic tumors. We have next focused on func- tional aspects and have silenced TGFBI expression in SW1222 human colorectal carcinoma cells. The suppression of TGFBI protein led to a marked decrease in cell migration (-70%) and proliferation (-30%) in vitro. To study the effects in vivo we have developed a novel animal model of colorectal carcinoma based on chicken chorioallantoic membrane (CAM) that mimics human CRC-LM. TGFBI silencing resulted in 50% reduction of tumor volume in the CAM tumor model. Notably, the tumors displayed a marked inhibition of vascularization, suggesting an additional anti-angiogenic effect. Indeed, SW1222 cells silenced for TGFBI expression secreted lower levels of VEGFA in vitro. Finally, we have investigated if TGFBI can be used as systemically reachable target for antibody-drug delivery. For this purpose we have The in vivo data demonstrated that TGFBI is an accessible tumor target. Conclusions : Taken together, the present study shows that TGFBI is essential for promoting the development of CRC- LM and therefore represents a promising target for designing novel therapeutic approaches. [less ▲]

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See detailCertificat d’université en tutorat à distance : une approche de formation isomorphique pour acquérir des compétences de e-tuteur
Denis, Brigitte ULg

in Tutorales (2014, March), 12

Depuis plus d'une dizaine d'années, de nombreux auteurs ont décrit les rôles des tuteurs dans les dispositifs de formation en ligne (Depover et al, 2011 ; Salmon, 2000). La "présence" et les interventions ... [more ▼]

Depuis plus d'une dizaine d'années, de nombreux auteurs ont décrit les rôles des tuteurs dans les dispositifs de formation en ligne (Depover et al, 2011 ; Salmon, 2000). La "présence" et les interventions de ces derniers s'avèrent un facteur important dans l'efficacité de tels dispositifs, qu'il s'agisse de maintien de la motivation des apprenants ou du processus d'apprentissage. La variété des méthodologies mises en œuvre dans les scénarios de formation (apprentissage collaboratif, coopératif, individuel...) entraînent des modalités d'interaction différentes entre e-tuteur et apprenants. Se basant sur les étapes de formation au e-tutorat décrites par Denis (2003), un processus original de formation de e-tuteurs est proposé afin de rencontrer la diversité et l'adéquation des profils à adopter selon le contexte considéré. Le scénario de formation au e-tutorat recourt au principe d'isomorphisme en pédagogie (Leclercq, 1998). Outre des apports théoriques relatifs à la problématique traitée et une approche réflexive sur cette dernière, les formés sont amenés à vivre différentes situations d'animation qui pourront (ou non) les inspirer dans leurs futures pratiques de tutorat à distance. Par ailleurs, la formation met l'accent sur le respect d'une triple concordance entre les compétences visées, les activités mises en place et les modalités d'évaluation. [less ▲]

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See detailAdherence to Continuous Positive Airway Pressure (CPAP) Therapy
Deflandre, Eric ULg; Degey, Stéphanie; BONHOMME, Vincent ULg et al

in CHEST (2014, March), 145

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See detailOrganized proteomic heterogeneity in colorectal liver metastases and implications for therapies
Turtoi, Andrei ULg; Blomme, Arnaud ULg; Debois, Delphine ULg et al

in Acta Gastro-Enterologica Belgica (2014, March), 77(1), 07

Introduction : Tumor heterogeneity is a major obstacle for developing effective anti-cancer treatments. Recent studies have pointed at large stochastic genetic heterogeneity within cancer lesions, where ... [more ▼]

Introduction : Tumor heterogeneity is a major obstacle for developing effective anti-cancer treatments. Recent studies have pointed at large stochastic genetic heterogeneity within cancer lesions, where no pattern seems to exist that would enable a more structured targeted therapy approach. Aim : Because to date no similar information is available at the protein (phenotype) level, we aimed at characterising the proteomic heterogeneity in human colorectal carcinoma (CRC) liver metastases. Methods & Results : We employed MALDI imaging-guided proteomics and explored the heterogeneity of extracellular distribution of over 1000 proteins we found unexpectedly that all liver metastasis lesions displayed a reproducible, zon- ally delineated, pattern of functional and therapeutic biomarker heterogeneity. Peritumoral region featured elevated lipid metabolism and protein synthesis, the rim of the metastasis displayed increased cellular growth, movement and drug metabolism whereas the center of the lesion was characterized by elevated carbohydrate metabolism and DNA- repair activity. From the aspect of therapeutic targeting zonal expression of known and novel biomarkers was evident, reinforcing the need to select several targets in order to achieve optimal coverage of the lesion. Finally we highlight two novel antigens, LTBP2 and TGFBI, whose expression is a consistent feature of CRC liver metastasis. Conclusions : proteome heterogeneity has a distinct, organized, pattern. This particular hallmark can now be used as a part of the strategy for developing rational therapies based on multiple sets of targetable antigens. [less ▲]

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See detailPrognostic value of FDG PET/CT in liver transplantation for hepatocarcinoma
DETRY, Olivier ULg; Govaerts, L; BLETARD, Noëlla ULg et al

in Acta Gastro-Enterologica Belgica (2014, March), 77(1), 08

AIM : FDG uptake has been shown to predict the outcome in large series of patients with hepatocarcinoma (HCC) in Asia, but few data are available regarding European populations. Our aim was to evaluate ... [more ▼]

AIM : FDG uptake has been shown to predict the outcome in large series of patients with hepatocarcinoma (HCC) in Asia, but few data are available regarding European populations. Our aim was to evaluate the prognostic value of pretreatment FDG PET-CT in patients treated by liver transplantation. Methods: We retrospectively analyzed the data of 27 patients (24 M and 3 W, mean age 58 ± 9 years). The mean follow-up was 26 ± 18 months (min 1 month, max 66 months). All patients had an FDG PET-CT before the transplantation. The FDG PET/CT was performed according to a standard clinical protocol: 4 MBqFDG/kg body weight, uptake 60 min., low-dose non-enhanced CT. We measured the SUVmax and SUVmean of the tumor and the normal liver. The tumor/liver activity ratios (RSUVmax and RSUVmean) were tested as prognostic factors and compared to the following conventional prognostic factors: MILAN, CLIP, OKUDA, TNM stage, alphafoetoprotein level, portal thrombosis, size of the largest nodule, tumor differentiation, microvascular invasion, underlying cirrhosis and liver function. Results : The DFS was 87.2% at 1y and 72.1% at 3y. The OS was 85.2% at 1y and 80.7% at 3y. According to an univariate Cox model, RSUVmax, RSUVmean and healthy liver were predictors of DFS and RSUVmax, RSUVmean, size of the largest nodule, CLIP, liver involvement>50%, and healthy liver predicted the OS. According to a multivariate Cox model, only RSUVmax predicted DFS and RSUVmax and liver involvement>50% predicted OS. An ROC analysis of the ratios showed that the 1.15 cut-off for RSUVmax was best for predicting both the DFS (Cox regression:HR 14.4, p=0.02) and OS (HR 5.6, p=0.049). The Kaplan-Meier curves and Logrank tests confirmed those results. Even though the MILAN criteria alone were not predictive, it is worth noting that none of the patients outside the MILAN criteria and with RSUVmax<1.15 relapsed. Conclusions: The RSUVmax is a strong prognostic factor for recurrence and death in patients with HCC treated by liver transplantation with a cut-off value of 1,15. further prospective studies should test whether the metabolic index should be systematically included in the preoperative assessment. [less ▲]

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See detailControlled DCD donation is part of the solution to liver graft shortage, regardless of donor age
DETRY, Olivier ULg; MEURISSE, Nicolas ULg; DELWAIDE, Jean ULg et al

in Acta Gastro-Enterologica Belgica (2014, March), 77(1), 16

Aim: Results of donation after circulatory death (DCD) liver transplantation (LT) are impaired by ischemic bile duct lesions caused by procurement warm ischemia. Donor age is a risk factor in deceased ... [more ▼]

Aim: Results of donation after circulatory death (DCD) liver transplantation (LT) are impaired by ischemic bile duct lesions caused by procurement warm ischemia. Donor age is a risk factor in deceased donor LT, and particularly in DCD-LT. At the authors institute, age is not an absolute exclusion criterion to discard DCD liver grafts, controlled DCD donors receive comfort therapy before withdrawal, and cold ischemia is minimized. The aim of the present study was to report on the results of the first 10 years of this experience, and particularly on graft survival and the rate of post-transplant biliary complications, according to DCD donor age. 
 Methods: The authors retrospectively studied a consecutive series of 70 DCD-LT performed from 2003 to 2012, with at least one year of follow-up. This series was divided according to donor’s age, including 32 liver grafts from donors <55years, 20 between 56 and 69 years, and 18 from older donors >69 years. The three groups were compared in terms of donor and recipient demographics, procurement and transplantation conditions, peak laboratory values during the first post-transplant 72 hours, and results at one and four years. Median follow-up was 43 months. 
 Results: Overall graft survival was 98.5%, 91.4% and 69.5% at 1 month, 1 year and 4 years, respectively, without graft loss secondary to ischemic bile duct lesions. Cancer was the primary cause of graft loss and patient death. No difference other than age was noted between the three groups in donor and recipient characteristics, and in procurement conditions. There was no primary non-function but one patient needed re-transplantation for artery thrombosis. Biliary complications occurred similarly in the three groups. Graft and patient survival rates were not different at one and four years between the three groups. During the study period, there was an increasing liver procurement and transplantation activity, and in 2012, 30% of performed LT were DCD-LT, allowing a mean LT waiting time of 66 days. 
 Conclusions: This study shows comparable results between controlled DCD-LT from younger and older donors. Donor age >50 years should not be a contraindication to DCD-LT if other donor risk factors (such as warm and cold ischemia time) are minimized. DCD-LT with short cold ischemia may provide a significant source of liver grafts, decreasing waiting time. [less ▲]

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See detailDe rol van de bibliotheek in tijden van information overload
Decoster, Sara ULg

in Cahiers de la Documentation = Bladen voor Documentatie (2014, March), 68(1),

Cet article étudie le rôle que peut jouer la bibliothèque en temps d'information overload et part des deux composantes de base du phénomène de l'infobésité : en premier lieu, un flot de données ... [more ▼]

Cet article étudie le rôle que peut jouer la bibliothèque en temps d'information overload et part des deux composantes de base du phénomène de l'infobésité : en premier lieu, un flot de données objectivement important, et, en second lieu, la manière dont ces données sont traitées par le sujet humain, l’usager. Pour gérer l’afflux de données constant, la bibliothèque offre d’abord un outillage technique. Le développement récent des outils « discovery » peut être resitué dans cette veine. Deuxièmement, c’est en investissant dans les compétences informationnelles des utilisateurs que la bibliothèque peut lutter contre le versant subjectif de l’infobésité. Dans ce processus, la communication joue un rôle primordial. [less ▲]

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See detailPrise en charge des enfants à risque de sevrage.
Counson, Florence; Decortis, Thierry; Kalenga, Masendu ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2014, March)

Description of care and outcomes of infants at risk of withdrawal syndrom from in utero exposure to addictive of psychotropic drugs.

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See detailFibromatose desmoide : une masse cervicale peu banale
Tribolet, Sophie ULg; Francotte, Nadine; Chantraine, Christophe et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2014, March)

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See detailUsing micro-injection technique to assess fungal toxicity in mosquito control
Bawin, Thomas ULg; Boukraa, Slimane; Seye, Fawrou et al

in Communications in Agricultural and Applied Biological Sciences (2014, February 07), 79(1), 181-185

Topical application of insecticidal compounds allows directly exposing these substances on insect tissues and measuring their toxicity while ignoring many factors. However, this technique remains ... [more ▼]

Topical application of insecticidal compounds allows directly exposing these substances on insect tissues and measuring their toxicity while ignoring many factors. However, this technique remains difficult to apply on mosquito larvae considering their aquatic lifestyle. Micro-injection could be used for the direct deposition of toxic compounds in the larvae. Capillaries exhibiting an injection tip with an external diameter of 0.5 mm have been designed from silica tubes. For each treatment, a capillary is mounted on a pump connected to a flow rate regulator. Culex quinquefasciatus larvae were injected with 10^7 spores/ml of entomopathogenic fungi (Aspergillus clavatus, Metarhizium anisopliae, Metarhizium sp.). Mortalities were recorded daily during 72h. The distribution of spores stained with methylene blue and injected into the body of larvae was also observed according to the system described. Results showed that spores were distributed over the whole body. The injection of Aspergillus clavatus, Metarhizium anisopliae and Metarhizium sp spores induced corrected mortalities of 62%, 53% and 57% after 72h, and differed statistically from control groups. Finally, post-mortem emergences of filaments from dead larvae were observed in the case of the three fungal strains confirming spore viability. Injection of inactivated spores (or inert bodies of similar size) could help to reject the hypothesis of a response due to the presence of foreign bodies. [less ▲]

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See detailIMPLEMENTATION OF A METAL STRUCTURED PACKING IN A FUNGAL BIOFILM REACTOR FOR THE PRODUCTION OF A RECOMBINANT PROTEIN BY ASPERGILLUS ORYZAE
Zune, Quentin ULg; Delepierre, Anissa; Toye, Dominique ULg et al

in Communications in Agricultural and Applied Biological Sciences (2014, February 07)

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See detailPhysico-chemical properties and aroma profile of Acacia Honey produced in Romania
Madas, Mariana-Niculina ULg; Francis, Frédéric ULg; Marghitas, L.A. et al

in Communications in Agricultural and Applied Biological Sciences (2014, February 07), 79(1), 133-135

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See detailOrigin and Pulsation of Hot Subdwarfs
Randall, Suzanna K; Fontaine, Gilles; Charpinet, Stéphane et al

in Proceedings of the International Astronomical Union (2014, February), 301

We briefly introduce hot subdwarfs and their evolutionary status before discussing the different types of known pulsators in more detail. Currently, at least six apparently distinct types of variable are ... [more ▼]

We briefly introduce hot subdwarfs and their evolutionary status before discussing the different types of known pulsators in more detail. Currently, at least six apparently distinct types of variable are known among hot subdwarfs, encompassing p- as well as g-mode pulsators and objects in the Galactic field as well as in globular clusters. Most of the oscillations detected can be explained in terms of an iron opacity mechanism, and quantitative asteroseismology has been very successful for some of the pulsators. In addition to helping constrain possible evolutionary scenarios, studies focussing on stellar pulsations have also been used to infer planets and characterize the rotation of the host star. [less ▲]

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See detailG-mode trapping and period spacings in hot B subdwarf stars
Charpinet, Stéphane; Van Grootel, Valérie ULg; Brassard, Pierre et al

in Proceedings of the International Astronomical Union (2014, February), 301

Hot B subdwarfs (sdB) are hot and compact helium core burning stars of nearly half a solar mass that can develop pulsational instabilities driving acoustic and/or gravity modes. These evolved stars are ... [more ▼]

Hot B subdwarfs (sdB) are hot and compact helium core burning stars of nearly half a solar mass that can develop pulsational instabilities driving acoustic and/or gravity modes. These evolved stars are expected to be chemically stratified with an almost pure hydrogen envelope surrounding a helium mantle on top of a carbon/oxygen enriched core. However, the sdB stars pulsating in g-modes show regularities in their observed period distributions that, surprisingly (at first sight), are typical of the behavior of high order g-modes in chemically homogeneous (i.e., non-stratified) stars. This led to a claim that hot B subdwarfs could be much less chemically stratified than previously thought. Here, we reinvestigate trapping effects affecting g-modes in sdB stars. We show that standard stratified models of such stars can also produce nearly constant period spacings in the low frequency range similar to those found in g-mode spectra of sdB stars monitored with Kepler. [less ▲]

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See detailPulsations in white dwarf stars
Fontaine, Gilles; Bergeron, Pierre; Brassard, Pierre et al

in Proceedings of the International Astronomical Union (2014, February), 301

We first present a brief description of the six distinct families of pulsating white dwarfs that are now known. These are all opacity-driven pulsators showing low- to mid-order, low-degree gravity modes ... [more ▼]

We first present a brief description of the six distinct families of pulsating white dwarfs that are now known. These are all opacity-driven pulsators showing low- to mid-order, low-degree gravity modes. We then discuss some recent highlights that have come up in the field of white dwarf asteroseismology. [less ▲]

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See detailElucidating the role of Bovine Leukemia Virus encoded micro-RNAs
Durkin, Keith ULg; Rosewick, Nicolas; Momont, Momont et al

in Retrovirology (2014, January 07), 11(1), 62

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See detailSperm Motility and Lactate production at different sperm concentrations
Ponthier, Jérôme ULg; De Tullio, Pascal ULg; Blommaert, Didier ULg et al

in Journal of Equine Veterinary Science (2014, January), 34(1), 75-76

Lactate production is associated with total spermatozoa concentration. It negatively affects preservation of total and progressive motility, showing an effect of by-products of anaerobic metabolism on ... [more ▼]

Lactate production is associated with total spermatozoa concentration. It negatively affects preservation of total and progressive motility, showing an effect of by-products of anaerobic metabolism on long-term storage. Moreover, our data show that non-progressive motile spermatozoa are highly associated to lactate concentration, and thus, anaerobic glycolysis. More studies are required to determine relative contributions of aerobiosis and anaerobiosis to spermatozoa motility under different storage conditions. [less ▲]

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See detailMigrations congolaises (RDC) en Belgique et postcolonialismes
Demart, Sarah ULg

in La lutte contre les discriminations au regard de l’histoire et de la mémoire coloniales : état des lieux (2014, January)

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See detailUse of automatic stapling device during castration to prevent (re)occurrence of inguinal hernia in horses with large vaginal rings.
Salciccia, Alexandra ULg; de la Rebière de Pouyade, Geoffroy ULg; Ponthier, Jérôme ULg et al

in Journal of Equine Veterinary Science (2014, January), 34(1), 99-100

(Re)ocurrence of inguinal hernia in case of very large vaginal rings may simply be prevented by closure of the vaginal tunic by TA staples during castration by inguinal approach. This method provides a ... [more ▼]

(Re)ocurrence of inguinal hernia in case of very large vaginal rings may simply be prevented by closure of the vaginal tunic by TA staples during castration by inguinal approach. This method provides a good resistance to internal pressure, appears to be safe, fast and easy to perform and may therefore be an interesting alternative to laparoscopic techniques when castration is considered. [less ▲]

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See detailEdging towards better accounting
Schumesch, Patrice ULg

in Accounting and Business Magazine of the Association of Certified Chartered Accountants (2014, January)

The ACCA's International Public Sector Conference explored the direction of public sector reporting, and rebuilding public trust through improved financial reporting. Other speakers included Carla Moordy ... [more ▼]

The ACCA's International Public Sector Conference explored the direction of public sector reporting, and rebuilding public trust through improved financial reporting. Other speakers included Carla Moordy of Monitory UK, Zinga Venner of the World Bank, and Professor Michael Parker of Henley Business School. [less ▲]

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See detailGalectins in cancer: jacks of all trades
Heusschen, Roy ULg; Schulkens, Iris; Muller, Joséphine ULg et al

in International Journal of Molecular Medicine (2014)

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See detailAnton de Kom, historiographe. La construction d’un passé national pour les esclaves du Surinam
Andringa, Kim ULg

in Amnis : Revue de Civilisation Contemporaine Europes/Amériques (2014), 13

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See detailPrognostic factors of death among nursing homes residents followed prospectively for a period of 2 years
Buckinx, Fanny ULg; Slomian, Justine ULg; Maquet, Didier ULg et al

in Osteoporosis International (2014), 25(2), 121-122

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See detailImpact of bone marrow lesion on the progression of knee osteoarthritis in the Sekoia study
Parsons, C; Edwards, MH; Bruyère, Olivier ULg et al

in Osteoporosis International (2014), 25(2), 142

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See detailAssociation between lean mass and hip bone mineral density
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Slomian, Justine ULg et al

in Arthritis and Rheumatism (2014), 66(11), 95

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See detailPercentage of women achieving non-osteoporotic BMD T-scores at the spine and hip over 8 years of denosumab treatment
Ferrari, S; Libanati, C; Lin, CJF et al

in Arthritis and Rheumatism (2014), 66(11), 986-987

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See detailEfficient finite element assembly of high order Whitney forms
Marsic, Nicolas ULg; Geuzaine, Christophe ULg

in IET Conference Proceedings (2014)

This paper presents an efficient method for the finite element assembly of high order Whitney elements. We start by reviewing the classical assembly technique and by highlighting the most time consuming ... [more ▼]

This paper presents an efficient method for the finite element assembly of high order Whitney elements. We start by reviewing the classical assembly technique and by highlighting the most time consuming part. Then, we show how this classical approach can be reformulated into a computationally efficient matrix - matrix product. We also address the problem of the basis orientation by considering more than one reference space. We conclude by presenting numerical results on a wave guide problem. [less ▲]

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See detailA Spatiotemporal Analysis of Membership: Formalizing the Space-Time Elements of Connection for Groups
Hallot, Pierre ULg; Stewart, Kathleen

in Proceedings of the AAG Annual Meeting (2014)

This research aims to formalize the spatiotemporal relationships of membership between individuals and the groups to which they belong. Specifically, we analyze how the membership to a community evolves ... [more ▼]

This research aims to formalize the spatiotemporal relationships of membership between individuals and the groups to which they belong. Specifically, we analyze how the membership to a community evolves over time considering past, present and future connections. The framework developed for this research is presented using an ontological approach. We demonstrate a specific domain ontology application for spatiotemporal membership using BFO2, an updated version of the Basic Formal Ontology. Key to this work is the representation of membership, modeled through different kinds of mereological relations possible with a group, for example, pre-member, active member, and alumni that capture how membership evolves and changes over time. The semantic web rule language (SWRL) is used to express the different spatiotemporal events that relate to membership and their consequences on membership such as subscription, graduation and reunion events. Mobility events are also included in the model. SWRL supports reasoning using the ontology and studying the evolution of membership between people and their various groups. We use the environment of a university community as an exemplar to develop and test the formalizations. However, the ideas are generalizable to a wide range of spatiotemporal domains, for example, these ideas hold for citizenship modeling or for consumers shopping at certain retail chains. The study of the evolution of membership connections between these entities and groups lends important insights for many different kinds of event planning. [less ▲]

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See detailComparison of continuous background in-situ and column integrated CO2 observations at Jungfraujoch with an urban site in the city of Bern
Schibig, Michael; Leuenberger, Markus; Nyfeler, Peter et al

in Geophysical Research Abstracts (2014), 16

A six and a half year (January 2005 to May 2011) comparison of CO2 concentration observations has been performed at Jungfraujoch, Switzerland and the city of Bern using two different measurement ... [more ▼]

A six and a half year (January 2005 to May 2011) comparison of CO2 concentration observations has been performed at Jungfraujoch, Switzerland and the city of Bern using two different measurement techniques run by the University of Bern (UBE) and the University of Liege (UL). The UBE systems at Jungfraujoch and Bern are both combined systems for atmospheric oxygen and CO2 measurements. The cryogenically dried air is analysed for CO2 with a Maihak analyser based on the broad-band infrared absorption technique. The measurement frequency is every second but the final reported data are averages of six minute periods. UL is measuring the solar infrared spectrum since 1950 at Jungfraujoch. On its way through the atmosphere, the solar spectrum is modulated depending on the abundant gas species and their amount in the column. Since some gases like CO2 absorb the solar infrared radiation at particular wavelengths and the extinction is proportional to the gas concentration, it is possible to determine the gas concentration in the column above the sensor. At the conference, we will present the three observational records for the six and a half year period. The results show for all three records a distinct, but different seasonality. The seasonalities of the UL and UBE record at Jungfraujoch are lower than the seasonality in the city of Bern, i.e. 4.5 ppm per year and 9 ppm per year for the column and the in- situ record respectively, whereas the seasonality in the city of Bern is 31 ppm per year. Also the maxima and minima of the Jungfraujoch measurements are delayed by several weeks compared to the measurements in the city of Bern. The annual increase of the CO2 concentration of the UBE and UL records of Jungfraujoch are in good agreement with 1.94 ppm per year and 1.90 ppm per year, respectively. The annual increase of the CO2 concentration at the urban site is a bit higher at 2.01 ppm per year. [less ▲]

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See detailImpact of bone marrow lesion on the progression of knee osteoarthritis in the SEKOIA study
Parsons, C; Edwards, MH; Bruyère, Olivier ULg et al

in Rheumatology (2014), 53(1), 130

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See detailDétection automatique de réminiscences potentielles de Xénophon chez Arrien
Vanhaegendoren, Koen ULg; Vandersmissen, Marc ULg

in Etudes Classiques (Namur, Belgium) (2014)

Depuis des siècles, les spécialistes et les savants des littératures grecque et latine se sont attachés à repérer les citations et les reprises d’un auteur chez un autre en raison de l’importance de ... [more ▼]

Depuis des siècles, les spécialistes et les savants des littératures grecque et latine se sont attachés à repérer les citations et les reprises d’un auteur chez un autre en raison de l’importance de l’imitatio et de l’aemulatio dans le processus de création littéraire des œuvres anciennes. Arrien de Nicomédie en est un parfait exemple puisqu’il s’inspira abondamment de son modèle admiré, Xénophon. C’est pourquoi, après avoir répertorié le plus grand nombre possible de réutilisations déjà mises au jour entre les deux historiens par les philologues de manière livresque, notre projet a pour but de détecter et de commenter de nouvelles réminiscences potentielles de Xénophon dans l’œuvre d’Arrien grâce à un logiciel développé spécifiquement à l’Université de Liège sur base de fichiers de textes lemmatisés en collaboration avec le LASLA. [less ▲]

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See detailUne ingénierie pour l’étude de la proportionnalité par confrontation à la non-proportionnalité via des manipulations
Lambrecht, Pauline; Henry, Valérie ULg

in Quaderni di Ricerca in didattica (2014), 24(1), 388

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See detailAn interaction map for HTLV-1 Tax and PDZ-containing proteins
Blibek, Karim ULg; Rambout, Xavier ULg; Beaufays, Jérome et al

in Retrovirology (2014), 11

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See detailQuels facteurs sociodémographiques influencent l'attitude des médecins généralistes envers la prévention ?
Vanmeerbeek, Marc ULg; Donneau, Anne-Françoise ULg; Monseur, Christian ULg

in Revue Médicale de Bruxelles (2014), 35(3 (Suppl)), 6

Objectifs En Belgique, les mesures de prévention médicalisées restent inéquitablement distribuées dans plusieurs domaines (vaccins, dépistages, conseil cardio-vasculaire, etc.). Une recherche antérieure ... [more ▼]

Objectifs En Belgique, les mesures de prévention médicalisées restent inéquitablement distribuées dans plusieurs domaines (vaccins, dépistages, conseil cardio-vasculaire, etc.). Une recherche antérieure au moyen d’une échelle d’attitude a mis en évidence trois facteurs pouvant modeler l’attitude des médecins généralistes (MG) envers la prévention : 1. Evaluation de pratique. 2. Sentiment de responsabilité envers la santé des patients. 3. Compétences professionnelles particulières (CPP) : références scientifiques, positionnement dans le système de soins, délégation de tâches à des paramédicaux. Cette étude a cherché à établir des profils de MG par rapport à la prévention, en croisant les scores sur ces trois facteurs et les variables sociodémographiques. Méthode Les réponses des 457 MG répondants à l’échelle d’attitude ont été soumis à des analyses multivariées, en prenant comme variables dépendantes les scores obtenus sur les trois facteurs, et comme variables indépendantes l’ancienneté, le sexe, la langue, le lieu de pratique, le travail dans un centre de prévention (ONE, planning, PSE), le type de pratique (solo ou divers types d’association). Résultats Le type de pratique est le seul déterminant qui influence les 3 facteurs, avec un gradient des pratiques solo vers les maisons médicales, en passant par les associations mono- puis pluridisciplinaires. Les MG ayant moins de 20 ans de pratique ont de meilleurs scores en évaluation et CPP. Les hommes ont de meilleurs scores en évaluation, et les pratiques urbaines se distinguent en CPP. La langue influence tantôt dans un sens tantôt dans l’autre. Il n’y a pas d’influence du fait de travailler dans un centre de prévention. Conclusion Une diffusion plus large et équitable des actes préventifs passe par la prise en compte de facteurs personnels et organisationnels propres aux MG. Les associations pluridisciplinaires semblent mieux préparées pour atteindre cet objectif. [less ▲]

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See detailDélires et Hallucinations : Echelle transdiagnostique d’auto-évaluation.
Beaupain, Margaux; Thirion, Julie; Wagener, Aurélie ULg et al

in Revue Francophone de Clinique Comportementale et Cognitive (2014), 19(3), 72

Introduction : Les délires et les hallucinations sont des symptômes majeurs présents chez 80% des personnes souffrant d’un trouble psychotique (e.g., bipolaire, schizophrène). Cependant, ces phénomènes ... [more ▼]

Introduction : Les délires et les hallucinations sont des symptômes majeurs présents chez 80% des personnes souffrant d’un trouble psychotique (e.g., bipolaire, schizophrène). Cependant, ces phénomènes sont également présents dans d’autres troubles psychiatriques (e.g., troubles anxieux, dépression) et chez 8% des individus tout venants (Linscott & Van Os, 2012) suggérant l’importance de les évaluer. D’après la littérature, les populations cliniques et non-cliniques se distinguent d’avantage à travers différentes dimensions telles que la détresse, la conviction et le contenu que par la fréquence (Lincoln, 2007). Cependant, les évaluations existantes se centrent principalement sur la fréquence des phénomènes, ce qui laisse beaucoup d’informations cliniques de côté. De plus, elles ne sont que rarement basées sur une approche en continuum permettant d’appréhender la complexité et l’hétérogénéité des phénomènes (allant des perceptions aberrantes jusqu’aux délires et hallucinations). Enfin, ce sont souvent des hétéroévaluations qui sont chronophages et requièrent du personnel qualifié alors que certaines études suggèrent une bonne validité des autoévaluations de ces phénomènes (Se Hyun et al., 2010). Afin de pallier ces limites, nous avons développé une échelle transdiagnostique d’auto-évaluation des idées délirantes et hallucinations en se basant sur une approche en continuum. Méthode : Une revue de la littérature sur les caractéristiques et outils d’évaluations des idées délirantes et des hallucinations a été réalisée. Vingt-quatre items parmi les plus discriminants ont été sélectionnés et adaptés. Pour chaque item, huit dimensions ont été sélectionnées : fréquence, détresse, interférence, conviction, état de conscience, contenu positif VS négatif, agréabilité et attribution interne VS externe. Les individus répondent d’abord à la fréquence sur une échelle de type Likert en 5 points (« Oui, ça m’arrive souvent » à « Non, ça ne m’est jamais arrivé »). Si la réponse est positive, les sept autres dimensions sont évaluées via une échelle visuelle analogique de 0 à 10. Perspectives: L’échelle est actuellement en cours de validation. Elle sera pré-testée auprès d’étudiants avant d’être validée auprès de populations cliniques et non-cliniques. A long terme, cette échelle transdiagnostique d’auto-évaluation pourrait être utilisée en clinique comme un outil favorisant une meilleure prise en charge de ces symptômes et comme un nouvel outil de recherche. [less ▲]

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See detailOdanacatib anti-fracture efficacy and safety in postmenopausal women with osteoporosis: results from the phase III long-term odanacatib fracture trial
McClung, MR; Langdahl, B; Papapoulos, S et al

in Arthritis and Rheumatism (2014), 66(11), 987

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See detailPrecision and Accuracy of Asteroseismology Applied to sdB stars Using the Forward Modeling Method
Charpinet, Stéphane; Van Grootel, Valérie ULg; Brassard, Pierre et al

in Astronomical Society of the Pacific Conference Series (2014), 481

Detailed seismic studies of hot B subdwarf (sdB) stars using the forward modeling approach provide measurements of their fundamental parameters at very interesting precisions. For instance, masses, radii ... [more ▼]

Detailed seismic studies of hot B subdwarf (sdB) stars using the forward modeling approach provide measurements of their fundamental parameters at very interesting precisions. For instance, masses, radii, and log g values derived this way are typically claimed at ∼ 1 − 2%, ∼ 0.5%, and ∼ 0.1 % precision, respectively. However, this method relies on still imperfect stellar models that contains various uncertainties associated with their inner structure and the underlying microphysics. A signature of these imperfections is the inability of current best-fit seismic models to reproduce all the observed oscillation frequencies at the precision of the observations. Therefore, the question of the accuracy (as opposed to the precision) of the derived parameters obtained from this approach is legitimate. Here, we revisit the question of precision and accuracy based on new, third generation, complete static models of sdB stars developed for asteroseismology and applied to the case of the eclipsing system PG 1336-018. This allows us to evaluate the reliability of the method and quantify the impact of various uncertainties in the stellar models on the derived stellar parameters. Finally, we discuss the intrinsic potential of asteroseismology for precise measurements of stellar parameters and show that we are far from having fully exploited this technique in terms of precision that can, in principle, be achieved. [less ▲]

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See detailOn Interpreting g-Mode Period Spacings in sdB Stars
Charpinet, Stéphane; Brassard, Pierre; Van Grootel, Valérie ULg et al

in Astronomical Society of the Pacific Conference Series (2014), 481

Long period B subdwarf (sdB) pulsators, when observed from space with the satellites CoRoT and Kepler, show particularly rich g-mode oscillation spectra with often hundreds of frequencies. In many of ... [more ▼]

Long period B subdwarf (sdB) pulsators, when observed from space with the satellites CoRoT and Kepler, show particularly rich g-mode oscillation spectra with often hundreds of frequencies. In many of these pulsation spectra, regularities in the observed period distributions typical of high order g-modes in chemically homogeneous stars have been reported. This led to a claim that sdB stars could be much less chemically stratified than previously thought. In this paper, we show that such an interpretation is unfounded. We reinvestigate trapping effects on g-modes in sdB stars in view of current observations and show that ”standard” stratified models can also produce nearly quasi-constant period spacings in the low frequency range which are comparable to those observed in the g-mode spectra of these stars. [less ▲]

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See detailBioactive Intraocular Lens – A Strategy to Control Secondary Cataract
Huang, Yi-Shiang ULg; Bertrand, Virginie ULg; Bozukova, Dimitriya et al

in IFMBE Proceedings (2014), 41

Cataract is the opacity of the lens, causing impairment of vision or even blindness. Today, a surgery is still the only available treatment. The intraocular lens (IOL) is a polymer implant designed to ... [more ▼]

Cataract is the opacity of the lens, causing impairment of vision or even blindness. Today, a surgery is still the only available treatment. The intraocular lens (IOL) is a polymer implant designed to replace the natural lens in the cataract surgery. However, the bioinert materials could not satisfy the unmet need in the secondary cataract control. Posterior capsular opacification (PCO, or Secondary Cataract), characterized by a thick and cloudy layer of lens epithelial cells (LECs), is the most common postoperative complication. In our research, a bioactive molecule is immobilized onto the conventional acrylic hydrophilic polymer pHEMA (Poly(2-hydroxyethyl methacrylate)) using oxygen plasma treatment followed by deposition. The RGD peptide sequence, being well-known for its ability to promote cellular attachment by binding to integrin receptors, is designed to stimulate the adhesion of LECs on the IOL. Our data show the peptide immobilized biomaterial not only exhibits similar optical property, but also reveals enhanced biological properties in cell adhesion and cell morphology maintenance. By means of surface functionalization of IOL to stimulate LECs adhesion, the secondary cataract could be controlled. [less ▲]

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See detailFunctional connectivity and recognition of familiar faces in Alzheimer’s disease
Kurth, Sophie ULg; Bahri, Mohamed Ali ULg; Moyse, Evelyne ULg et al

in Frontiers in Human Neuroscience (2014)

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See detailOdanacatib anti-fracture efficacy and safety in postmenopausal women with osteoporosis: results from the phase III long-term odanacatib fracture trial
McClung, MR; Langdahl, B; Papapoulos, S et al

in Osteoporosis International (2014), 25(5), 573-575

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See detailGalectin expression in the multiple myeloma microenvironment
Muller, Joséphine ULg; CAERS, Jo ULg; Binsfeld, Marilène ULg et al

in Belgian Journal of Hematology (2014)

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See detailEfficient combination of pairwise feature networks
Bellot, Pau; Meyer, Patrick ULg

in JMLR: Workshop and Conference Proceedings (2014)

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See detailA volatile sex pheromone in the invasive ladybeetle Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae)
Fassotte, Bérénice ULg; Fischer, Christophe ULg; Durieux, Delphine ULg et al

in Communications in Agricultural and Applied Biological Sciences (2014), 79(1), 79-81

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See detailObservational Asteroseismology of Hot Subdwarf Stars with the Mont4K/Kuiper Combination at the Steward Observatory Mount Bigelow Station
Fontaine, Gilles; Green, Elizabeth M.; Charpinet, Stéphane et al

in Astronomical Society of the Pacific Conference Series (2014), 481

In the last few years, we have carried out several extensive observational campaigns on pulsating hot subdwarf stars using the Mont4K CCD camera attached to the 1.55 m Kuiper Telescope on Mount Bigelow ... [more ▼]

In the last few years, we have carried out several extensive observational campaigns on pulsating hot subdwarf stars using the Mont4K CCD camera attached to the 1.55 m Kuiper Telescope on Mount Bigelow. The Mont4K is a joint partnership between the University of Arizona and Universite ́ de Montre ́al. It was designed and built at Steward Observatory. Using the Mont4K/Kuiper combination, we have so far, and among others, gathered high-sensitivity broadband light curves for PG 1219+534, PB8783, HS 0702+6043, and Feige 48. We report very briefly on some of the most interesting observational results that came out of these campaigns. [less ▲]

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See detailMode Identification in Subdwarf B Stars from Multi-Wavelength Observations
Randall, Suzanna K; Fontaine, Gilles; Brassard, Pierre et al

in Astronomical Society of the Pacific Conference Series (2014), 481

We present several examples of partial mode identification for rapidly pulsating subdwarf B stars on the basis of multi-colour observations. Three targets (V391 Per, Balloon 090100001, and EC 11583−2708 ... [more ▼]

We present several examples of partial mode identification for rapidly pulsating subdwarf B stars on the basis of multi-colour observations. Three targets (V391 Per, Balloon 090100001, and EC 11583−2708) were analysed from multi-colour photometry, while studies were conducted from time-series spectrophotometry for two further stars (EC 20338−1925 and EC 01541−1409). In all cases, periodicities strongly dominating the frequency spectrum are associated with radial modes, indicating a clear hierarchy according to visibility when integrating over the visible disk of the star. [less ▲]

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See detailPrevalence of sarcopenia according to different diagnostic tools
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Slomian, Justine ULg et al

in Journal of Frailty & Aging (2014), 3(1), 43

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See detailEvolution over two years of functional and motor abilities among nursing home residents
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Slomian, Justine ULg et al

in Journal of Frailty & Aging (2014), 3(1), 45

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See detailReaching the 1% accuracy level on stellar mass and radius determinations from asteroseismology
Van Grootel, Valérie ULg; Charpinet, Stephane; Fontaine, Gilles et al

in Proceedings of the International Astronomical Union (2014), 301

Asteroseismic modeling of subdwarf B (sdB) stars provides measurements of their fundamental parameters with a very good precision; in particular, the masses and radii deter- mined from asteroseismology ... [more ▼]

Asteroseismic modeling of subdwarf B (sdB) stars provides measurements of their fundamental parameters with a very good precision; in particular, the masses and radii deter- mined from asteroseismology are found to typically reach a precision of 1% containing various uncertainties associated with their inner structure and the underlying microphysics (composition and transition zones profiles, nuclear reaction rates, etc.). Therefore, the question of the accuracy of the stellar parameters derived by asteroseismology is legitimate. We present here the seismic modeling of the pulsating sdB star in the eclipsing binary PG 1336-018, for which the mass and the radius are independently and precisely known from the modeling of the reflection/irradiation effect and the eclipses observed in the light curve. This allows us to quantitatively evaluate the reliability of the seismic method and test the impact of uncertainties in our stellar models on the derived parameters. We conclude that the sdB star parameters inferred from asteroseismology are precise, accurate, and robust against model uncertainties. [less ▲]

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See detailImplication des troubles métaboliques dans la progression radiologique de la gonarthrose : analyse post-hoc issue de l'essai randomisé SEKOIA
Eymard, F; Parsons, C; Edwards, M et al

in Revue du Rhumatisme (2014), 81(Suppl. 1), 92

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See detailPreferences of patients for osteoporosis drug treatment: a cross-european discrete choice experiment
Hiligsmann, Mickaël ULg; Dellaert, BG; Dirksen, CD et al

in Osteoporosis International (2014), 25(2), 227-228

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See detailQuality of life benefits of knee arthroplasty for osteoarthritis
NEUPREZ, Audrey ULg; François, Garance ULg; KURTH, William ULg et al

in Osteoporosis International (2014), 25(2), 40

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See detailFurther reduction in nonvertebral fracture rate is observed following 3 years of denosumab treatment: results with up to 7 years in the freedom extension
Ferrari, S; Adachi, JD; Lippuner, K et al

in Osteoporosis International (2014), 25(2), 56

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See detailCould internet use be promising in health prevention and promotion in menopausal women ? A preliminary report
Slomian, Justine ULg; Streel, Sylvie ULg; Appleboom, G et al

in Osteoporosis International (2014), 25(2), 309

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See detailThe Mass Distribution of sdB Stars Derived by Asteroseismology and Other Means: Implications for Stellar Evolution Theory
Van Grootel, Valérie ULg; Charpinet, Stéphane; Fontaine, Gilles et al

in Astronomical Society of the Pacific Conference Series (2014), 481

Understanding the formation of sdB stars is one of the remaining challenges of stellar evolution theory. Competing scenarios have been proposed to account for the existence of such evolved objects. They ... [more ▼]

Understanding the formation of sdB stars is one of the remaining challenges of stellar evolution theory. Competing scenarios have been proposed to account for the existence of such evolved objects. They give quite different mass distributions for resulting sdB stars. Detailed asteroseismic analyses, including mass estimates, of 15 pulsating hot B subdwarfs have been published in the past decade. Masses have also been reliably determined by light curve modeling and spectroscopy for 7 sdB components of eclipsing or reflection binaries. We present here the empirical mass distribution of sdB stars on the basis of these samples. Implications are also briefly discussed. [less ▲]

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See detailRisk factors for falls among elderly nursing home residents: a 2-year prospective study
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Slomian, Justine ULg et al

in Osteoporosis International (2014), 25(2), 36-37

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See detailEconomic evaluation of an osteoporosis screening campaign: using FRAX as a prescreening tool
Hiligsmann, Mickaël ULg; Ben Sedrine, Wafa ULg; Bruyère, Olivier ULg et al

in Osteoporosis International (2014), 25(2), 38-39

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See detailImpact of components of the metabolic syndrome on progression of knee osteoarthritis in the Sekoia study
Parsons, C; Edwards, MH; Eymard, F et al

in Osteoporosis International (2014), 25(2), 230

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See detailPatterns of difficult cases for breast irradiation: where multi-beam IMRT and SIB should be the primary choice
Ben Mustapha, S.; Dechambre, D.; Mievis, C. et al

in Radiother Oncol (2014), ESTRO 33

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See detailChallenges for the development of bone forming agents in Europe: introduction
Kanis, JA; Rizzoli, R; Cooper, C et al

in Osteoporosis International (2014), 25(2), 66-67

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See detailPrevalence of sarcopenia according to different diagnostic tools
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Slomian, Justine ULg et al

in Osteoporosis International (2014), 25(2), 115

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See detailEvolution over two years of functional and motor abilities among nursing home residents
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Slomian, Justine ULg et al

in Osteoporosis International (2014), 25(2), 121

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See detailEight years of denosumab treatment in postmenopausal women with osteoporosis: results from the first five years of the freedom extension
Papapoulos, S; Lippuner, K; Roux, C et al

in Osteoporosis International (2014), 25(2), 46-47

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See detailStreamlined clinical CBCT protocols: Reduced dose and variation and maintained image quality
Devillers, M.; Lakosi, F.; Janvary, L. et al

in Radiother Oncol (2014), ESTRO 33

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See detailModeling the hot subdwarf PB 8783 by asteroseismology
Van Grootel, Valérie ULg; Charpinet, Stephane; Fontaine, Gilles et al

in Astronomical Society of the Pacific Conference Series (2014), 481

We present the preliminary seismic modeling of one of the hottest and most compact subdwarf pulsators, PB 8783 (EO Ceti). This is a well observed hot subdwarf star, including a 78 d campaign in white ... [more ▼]

We present the preliminary seismic modeling of one of the hottest and most compact subdwarf pulsators, PB 8783 (EO Ceti). This is a well observed hot subdwarf star, including a 78 d campaign in white light photometry that we carried out at Mount Bigelow, Arizona, during the fall 2007. PB 8783 has also been observed at length in spectroscopy, revealing a spectrum highly contaminated by a main sequence companion. It is extremely difficult to disentangle the contribution of the two components and, as a consequence of this, the exact nature of the hot subdwarf (sdB or sdO star) is undetermined. We propose here to test the two hypotheses by asteroseismology. Although the sdB possibility cannot be excluded, the pulsation modes observed in PB 8783 are much better accommodated in the case of an sdO star. [less ▲]

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See detailYearly Follow-up of Methane Turbulent Exchange Over an Intensively Grazed Pasture in Belgium
Dumortier, Pierre ULg; Aubinet, Marc ULg; Beckers, Yves ULg et al

in Communications in Agricultural and Applied Biological Sciences (2014), 79(1), 91-96

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See detailLes récits numériques : de nouvelles formes narratives ?
Hurel, Pierre-Yves ULg

in L'espace de publication de Culture Numérique (2014)

Face aux discours techno-enthousiastes sur les innovations des récits numériques, des études de l’hyperfiction cherchent à définir les nouveautés réelles apportées par le média informatique. Cet article ... [more ▼]

Face aux discours techno-enthousiastes sur les innovations des récits numériques, des études de l’hyperfiction cherchent à définir les nouveautés réelles apportées par le média informatique. Cet article s’inscrit dans ce courant en comparant les récits interactifs numériques aux non-numériques, tels que les jeux de rôle, le théâtre expérimental ou les livres dont vous êtes le héros. Cette comparaison se fait en deux temps : d’abord le rapprochement par les caractéristiques narratives, puis la distinction par les spécificités des supports. Elle nuance le caractère nouveau de l’arborescence, de l’émergence, de l’hybridation de l’avatar et de spatialité ; et cherche à déterminer des caractéristiques propres au numérique. [less ▲]

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See detailFacteurs de risque de chute chez des sujets résidant en maison de repos : étude prospective d'une durée de 2 ans
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Slomian, Justine ULg et al

in Gériatrie et Psychologie Neuropsychiatrie du Vieillissement (2014), 12(1), 164-165

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See detailFacteurs pronostiques de décès chez des sujets résidant en maison de repos suivis d'une manière prospective pendant une période de 2 ans
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Slomian, Justine ULg et al

in Gériatrie et Psychologie Neuropsychiatrie du Vieillissement (2014), 12(1), 73-74

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See detailVitamine D et sujet âgé
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Gériatrie et Psychologie Neuropsychiatrie du Vieillissement (2014), 12(1), 5-6

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See detailImpact of components of the metabolic syndrome on knee osteoarthritis progression in the SEKOIA study
Eymard, F; Edwards, M; Parsons, C et al

in Osteoarthritis and Cartilage (2014), 22(1), 376

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