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See detailSpectral Modelling of Massive Binary Systems: The Example of LZ Cep
Palate, Matthieu ULg; Rauw, Grégor ULg; Mahy, Laurent ULg

in Central European astrophysical bulletin (2013)

Despite their importance for many astrophysical processes, massive stars are still not fully understood. Massive binaries offer an attractive way to improve our knowledge of the fundamental properties of ... [more ▼]

Despite their importance for many astrophysical processes, massive stars are still not fully understood. Massive binaries offer an attractive way to improve our knowledge of the fundamental properties of these objects. However, some secondary effects are known to generate variations in the spectra of massive binaries, rendering their analyses more difficult. We present here a new approach to the computation of synthetic spectra of massive binaries at different phases of their orbital cycle. Our model starts with the Roche potential modified by radiation pressure and accounts for the influence of the companion star on the shape and physical properties of the stellar surface. We further account for gravity darkening and reflection effects to compute the surface temperature. Once the local gravity and temperature are determined, we interpolate in a grid of NLTE plan-parallel atmosphere model spectra to obtain the local contribution to the spectrum at each surface points. Then we sum all the contributions, accounting for the Doppler shift, and limb-darkening to obtain the total spectrum. The computation is repeated for different orbital phases and can be compared to the observations to determine the best parameters. We illustrate our method through the example of the LZ Cep system (O9III + ON9.7V). [less ▲]

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See detailOleuropein or rutin consumption decreases the spontaneous development of OA in Hartley guinea pig
Sanchez, Christelle ULg; Horcajada, Marie-Noëlle; Membrez, Fanny et al

in Arthritis and Rheumatism (2013), 65

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See detailIntraperitoneal Adhesions After Open or Laparoscopic Abdominal Procedure: An Experimental Study in the Rat.
Arung, Willy; Drion, Pierre ULg; Honoré, Pierre ULg et al

in Surgical Endoscopy (2013), 27

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See detailHerbaceous Plant Availability and Use by Western Lowland Gorillas in South East Cameroon
Willie, Jacob; Tagg, Nikki; Petre, Charles-Albert ULg et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84

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See detailFeasibility and accessibility to the laparoscopic procedures in University Hospital of Kinshasa
Nsadi Fwene, Berthier; Veyi Tadulu, D.; Kazadi Mutshim, JM et al

in Surgical Endoscopy (2013), 27

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See detailHypovitaminosis D and osteoporosis in burn patients: are the current practices enough ?
ROUSSEAU, Anne-Françoise ULg; LEDOUX, Didier ULg; DAMAS, Pierre ULg et al

in Osteoporosis International (2013), 24(Suppl 1), 377

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See detailQuantitative determination of non persistent endocrine disruptors in human urine
Dewalque, Lucas ULg; PIRARD, Catherine ULg; DUBOIS, Nathalie ULg et al

in Acta Clinica Belgica (2013), 68(6),

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See detailOptimizing scale search in species distribution models
Serckx, Adeline ULg; Huynen, Marie-Claude ULg; Beudels-Jamar, Roseline et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84

The influence of spatial scale on ecological processes and pattern formation, such as species distribution is a major research topic since decades. It has become even more relevant in the context of ... [more ▼]

The influence of spatial scale on ecological processes and pattern formation, such as species distribution is a major research topic since decades. It has become even more relevant in the context of global change. In many studies the influence of a predictor on a response derived over multiple and discrete spatial scales is evaluated. Due to inherent issue of multiple testing, this approach can be problematic. In this study on bonobos distribution, we suggest a 3-steps procedure that overcomes this problem. It takes into account the decay of a predictor by using a weighting function of distance to the observation of interest. We use variables to account for human pressure, food availability, patchy structure of the forest and nesting sites re-use. In a first step, we run a model with a fixed scale for every predictor based on expert opinion. For significant variables, we derive then in a second step the distance weighted influence over a range of scales. This helps to narrow down the search for the final model parameter estimates. Findings indicate that bonobo distribution is driven on the intermediate scale by forest patches structure. Food availability explains their abundance only at smaller scales. Those results demonstrate the sadly well-known influence of habitat fragmentation on animals’ density and distribution but also highlight the importance to understand influences of scale, the animal perceptions of their environment, by using appropriate statistical procedures. Our method can be particularly useful to formulate specific management hypotheses for conservation. Furthermore, its principles can be of use to other types of studies, such as behavior. [less ▲]

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See detailProbing the phase of the elastic $pp$ scattering amplitude with vortex proton beams
Ivanov, Igor ULg

in AIP Conference Proceedings (2013)

We show that colliding vortex proton beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the scattering amplitude changes with the scattering angle. In ... [more ▼]

We show that colliding vortex proton beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the scattering amplitude changes with the scattering angle. In elastic $pp$ scattering, this will open a novel way to measure the parameter $\rho(t)$ and probe the real part of the Pomeron. [less ▲]

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See detailPhysico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration
Nasir, Mehmet Nail ULg; Legrand, Vincent; Gatard, Sylvain et al

in MATEC Web of Conferences (2013), 4

Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the ... [more ▼]

Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the pharmaceutical and cosmetic fields. Until now, no detailed analyses of the physico-chemical properties of these compounds have been undertaken. Two symmetrical D-xylose-based bolaforms were chemically synthesized where the two xylose heads are linked via an acetal link to a hydrocarbon chain containing 18 carbon atoms and an unsaturation. The two bolaforms differ only by their anomeric configuration: or The bolaform exhibits interfacial properties at the air-water interface which is not the case for the . FTIR spectroscopy showed that the interactions between the bolaform and POPC, a model phospholipid, involve the carbonyl groups of the phospholipid [less ▲]

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See detailSpatial distribution of erosion and deposition on an agricultural watershed
Pineux, Nathalie ULg; Colinet, Gilles ULg; Degré, Aurore ULg

in Geophysical Research Abstracts (2013), 15

To better understand the agricultural landscapes evolution becomes an essential preoccupation and, for this, it is needed to take into account the sediments deposition, in a distributed way. As it is not ... [more ▼]

To better understand the agricultural landscapes evolution becomes an essential preoccupation and, for this, it is needed to take into account the sediments deposition, in a distributed way. As it is not possible in practice to study all terrestrial surfaces in detail by instrumenting sectors to obtain data, models of prediction are valuable tools to control the current problems, to predict the future tendencies and to provide a scientific base to the political decisions. In our case, a landscape evolution model is needed, which aims at representing both erosion and sedimentation and dynamically adjusts the landscape to erosion and deposition by modifying the initial digital elevation model. The Landsoil model (Landscape design for Soil conservation under soil use and climate change), among others, could fulfil this objective. It has the advantage to take the soil variability into account. This model, designed for the analysis of agricultural landscape, is suitable for simulations from parcel to catchment scale, is spatially distributed and event-based. Observed quantitative data are essential (notably to calibrate the model) but still limited. Particularly, we lack observations spatially distributed on the watershed. For this purpose, we choose a watershed in Belgium (Wallonia) which is a 124 ha agricultural zone in the loamy region. Its slopes range from 0% to 9%. To test the predictions of the model, comparisons will be done with: - sediment measurements which are done with water samplings in four points on the site to compare the net erosion results; - sediment selective measurements (depth variation observed along graduated bares placed on site) to compare the erosion and deposition results; - very accurate DSM’s (6,76 cm pixel resolution X-Y) obtained by the drone (Gatewing X100) each winter. Besides planning what the landscape evolution should be, a revision of the soil map (drew in 1958) is organized to compare with the past situation and establish how the landscape moved in 50 years. The first results of the sediment measurements and of the pictures of the drone will be showed in the presentation. [less ▲]

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See detailSiblings and coming-out
Haxhe, Stéphanie ULg; D'Amore, Salvatore ULg

in Psychology, Community & Health (2013), 2(2), 162

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See detailThe neural correlates of recollection and familiarity during aging
Angel, Lucie; Bastin, Christine ULg; Genon, Sarah ULg et al

in Journal of Psychophysiology (2013), 27(Suppl 1), 48

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See detailProspective study of an advanced nurse triage for a target pathology at the admission in the emergency department
JOBE, Jérôme ULg; VANDERCLEYEN, C; Ghuysen, Alexandre ULg et al

in Acta Clinica Belgica (2013), 68(6), 2

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See detailFirst steps towards an explicit modeling of aba production and translocation in relation with the water uptake dynamics
Lobet, Guillaume ULg; Pagès, Loic; Draye, Xavier

in Acta Horticulturae (2013), 991

Water flow in the plant continuum is thought to be controlled by the leaf, xylem and the root radial conductances. Leaf conductance is widely recognized as the master control in the system as it can act ... [more ▼]

Water flow in the plant continuum is thought to be controlled by the leaf, xylem and the root radial conductances. Leaf conductance is widely recognized as the master control in the system as it can act as a switch in the water flow, even under high transpiration demand. The control of the stomatal aperture by the plant has been the object of numerous research projects since decades and different models have been developed to study stomatal regulation. The plant hormone abscisic acid (ABA) produced in the leaves acts as an endogenous signal triggering stomatal closure, but is also thought to act as a long distance signal that is produced by roots experiencing water deficit. However, the relative contributions of leaf-supplied ABA, root-supplied ABA and xylem water potential in the regulation of water flow remains a matter of controversy. Using a novel functional structural plant model (PlaNet-Maize-ABA), we report here a first attempt to explicitly simulate ABA production, degradation, translocation in all plant organs and their effect on the transpiration flow. [less ▲]

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See detailSurface and lipid interaction properties of novel rhamnolipids to explain their eliciting activity
Nasir, Mehmet Nail ULg; Monhonval, Pierre; Nott, Katherine ULg et al

in European Biophysics Journal [=EBJ] (2013), 42(S1), 168

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See detailEffect of abrupt preload reduction on left atrial and ventricular pressures in a multi-scale mathematical model of the cardiovascular system
Pironet, Antoine ULg; Dauby, Pierre ULg; Kosta, Sarah ULg et al

in European Heart Journal Supplements : Journal of the European Society of Cardiology (2013), 34

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See detailImproving the Accuracy of Monitoring Great Apes in the Wild: A Case Study from Southeast Cameroon
Tagg, Nikki; Willie, Jacob; Petre, Charles-Albert ULg

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84

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See detailSystemic Active and Total Myeloperoxidase Levels in Coronary Artery Disease.
GACH, Olivier ULg; MAGNE, Julien ULg; Franck, Thierry ULg et al

in Cardiology (2013), 126(Suppl. 2), 1-521

Backgound: Measurement of total Myeloperoxidase (MPO) by ELISA is considered as a marker of neutrophil activation but is not the true indicator of the degree of its activity. In a dynamic pathology such ... [more ▼]

Backgound: Measurement of total Myeloperoxidase (MPO) by ELISA is considered as a marker of neutrophil activation but is not the true indicator of the degree of its activity. In a dynamic pathology such as atherosclerosis, it may be important to measure the real active part of MPO because it represents the true witness of the oxidant potential of the enzyme. Aim: To identify the relation between coronary artery disease identified by coronaro-angiography on measured serum total and active MPO levels and evaluate the correlation between these MPO levels and the presence of clinically defined unstable condition. Methods: Prospective analyse of serum samples of patients before (within 30 min) coronaro-angiography. Total and active MPO concentrations were assessed by sandwich Elisa and SIEFED® method’s respectively. Results: Two hundred and twenty patients were included in this study (age: 66.1±10.7 years, 67% of male). Among these, 62% presented significant coronary artery disease (stenosis more than 60% at least in one épicardial coronary artery). Twenty four patients (11%) presented unstable coronary syndrome. Mean active and total MPO in the general population were 50.1±63.5 and 147.6±223.3 ng.mL-1 respectively. In comparison, mean active MPO was 47.1±47.9 ng.mL-1 in stable patients and 75.1±135.2 ng.mL-1 in unstable patients (p=0.04). Mean total MPO was 146.3±224.7 ng.mL-1 in stable patients and 158.2±215.8 ng.mL-1 in the unstable’s one (p=0.8). There was a significant correlation between active MPO levels and instability (r=0.14, p=0.04) not present for total MPO levels (r=0.016, p=0.8). Conclusion: We observed a correlation between active MPO and clinical instability while there was no correlation with total MPO. Our preliminary results suggest that this marker could be a powerful indicator of instability which could possess an important prognostic impact. This hypothesis requires an evaluation in wider population and during a prolonged follow-up. [less ▲]

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See detailQuadripulse Repetitive Transcranial Magnetic Stimulation on Visual Cortex for Chronic Migraine Prevention: A Pilot-Trial
Sasso d'Elia, Tullia; Vigano, Alessandro; Fataki, Michel et al

in Cephalalgia : An International Journal of Headache (2013), 33(8), 49

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See detailDéveloppement et validation de la version française d'un questionnaire traitant des attentes des patients dans l'arthrose des membres inférieurs
NEUPREZ, Audrey ULg; Delcour, JP; Fatemi, F et al

in Revue du Rhumatisme (2013), 80(S1), 181

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See detailDes ambassadeurs entre Liège et Bourgogne: Pour une étude des relations diplomatiques des pouvoirs liégeois avec les ducs Valois
Masson, Christophe ULg

in Publication du Centre Européen d'Etudes Bourguignonnes (2013), LIII(2013), 51-66

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See detailExperimental and numerical study of TA6V mechanical behavior under different quasi-static strain paths at room temperature
Gilles, Gaëtan ULg; Habraken, Anne ULg; Cazacu, Oana et al

in AIP Conference Proceedings (2013), 1532

This paper presents an experimental study of the quasi-static mechanical behavior of TA6V titanium alloy. Different monotonic tests were carried out in several orientations in the plane of the sheet in ... [more ▼]

This paper presents an experimental study of the quasi-static mechanical behavior of TA6V titanium alloy. Different monotonic tests were carried out in several orientations in the plane of the sheet in order to characterize the anisotropy and the tension-compression asymmetry exhibited by the material. Initial yielding is modeled by the phenomenological CPB06 criterion and Voce's isotropic hardening is used to describe its evolution. The simulation of a deep-drawing process is performed using the proposed constitutive modeling and compared with experimental data. [less ▲]

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See detailPreliminary data on plicathyridines (Brachiopoda) from the Frasnian of southern Belgium and the Middle East (Afghanistan, Iran)
Mottequin, Bernard ULg; Marion, Jean-Marc ULg; Brice, Denise

in Documents de l’Institut Scientifique (Rabat) (2013), 26

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See detailEstimation of the fascine efficiency in terms of runoff infiltration and sediments deposition
Degré, Aurore ULg; Pineux, Nathalie ULg; Cantreul, Vincent ULg et al

in Geophysical Research Abstracts (2013), 15

Runoff inundations and mudflows are more and more frequent phenomena. In 2011, Belgium had a lot of its municipalities affected by this problematic. Since then, mitigation measures are more and more set ... [more ▼]

Runoff inundations and mudflows are more and more frequent phenomena. In 2011, Belgium had a lot of its municipalities affected by this problematic. Since then, mitigation measures are more and more set up in agricultural watersheds. The fascines are one of these measures which allow to protect the public and private infrastructures and in the same way, which don’t reduce the famers productivity. They consist in branches faggots piled up between two rows of stakes. These linear constructions are mainly put in place across concentrated runoff axis in order to slow down the water and to filter the mud. Only few quantifications of their effectiveness (in terms of flow and concentration water reduction) exist and are however needed to better recommend these types of mitigation measures. Our experiment aims at measuring discharge and mud concentration reduction due to the fascines in a completely defined context. The tests were realised through fascines planted in field border. A watertight surface of 2,45m to 0,80m carries the water to the fascines. Three types of fascines were tested (willow wood fascine, straw fascine, straw compacted fascine), three different water flows were applied (0,5L/s, 3L/s and 6L/s) and three water concentration in dry soil (13g/L, 26g/L, 38g/L) were used. The different factor combinations were tested. The results show that we can expect a reduction of 60% of the flow for the biggest water flows (proportional efficiency with the water flow). The factor interaction study doesn’t allow to see a difference between the type. About the sediment water concentration, the filtration can reach 50%, the fascine with wood faggots showing a better efficiency. Finally, the difference between the fascine type show that straw fascine can support a biggest watershed (25 hectares) than the wood faggot fascine can (5-10 hectares) but during a smaller return period (one year against five years). [less ▲]

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See detailStudy on the sensitivity of three oat varieties to the saddle gall midge, Haplodiplosis marginata (von Roser) (Diptera: Cecidomyiidae)
Censier, Florence ULg; Chavalle, Sandrine; San Martin y Gomez, Gilles et al

in Communications in Agricultural and Applied Biological Sciences (2013), 78(2), 287-292

The saddle gall midge, Haplodiplosis marginata (von Roser, 1840) is a univoltine pest of cereals which occurs in Europe. The larvae feed on stems and attractive saddle-shaped depressions, driving to ... [more ▼]

The saddle gall midge, Haplodiplosis marginata (von Roser, 1840) is a univoltine pest of cereals which occurs in Europe. The larvae feed on stems and attractive saddle-shaped depressions, driving to important yield losses when the galls are numerous. After 40 years without any reporting, large populations of H. marginata and important damage have been observed since 2010 in wheat crops in Belgium, especially in the Flemish Polders where clay soils and intensive farming of cereals favour heavy infestations. According to some research conducted in the 1960s during the last outbreak, oat (Avena sativa L.) is known to be one of the less favourable hosts to the saddle gall midge. Our study was performed in order to assess the host sensitivity of three oat varieties currently grown in Belgium: EVITA, EFFEKTIV and FREDDY. Therefore, oat varieties were sown on infested soil in two separate enclosures in a glasshouse. In the first enclosure, only the three oat varieties were grown; in the second one, these three oat varieties were grown together with two varieties of spring wheat: GRANNY and KWS CHAMSIN. Two parameters were measured: the percentage of leaves with laid eggs, and the number of galls per stem. The percentage of leaves with eggs showed that the infestation was significantly lower on oats when they were in presence of wheat. The egg infestation was also significantly higher on wheat than on oat, which means oat is a much less favourable host plant than spring wheat for egg laying. Oat varieties were significantly different from each other regarding the number of galls per stem, but with very little damage compared to wheat. The FREDDY variety even seemed to be completely resistant to saddle gall midge, as no galls were observed although there was a similar percentage of leaves with eggs for the three oat varieties. Cropping oat could thus contribute to reduce infestations of H. marginata. [less ▲]

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See detailInfusion of CliniMACS (Myltenyi Biotec) Enriched Regulatory T Cells Delays Experimental Xenogeneic Graft-versus-Host Disease
Hannon, Muriel ULg; Lechanteur, C.; Somja, Joan ULg et al

in Belgian Journal of Hematology (2013), Abstracts book(Supplement of 28th General Meeting of the Belgian Hematological Society), 15

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See detailIndirect comparison of bazedoxifene vs. oral bisphosphonates for the prevention of vertebral fractures in postmenopausal osteoporotic women
Reginster, Jean-Yves ULg; Ellis, AG; Luo, X et al

in Osteoporosis International (2013), 24(1), 37

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See detailComparing Co-Parenting Among Gay- and Straight-Parented Triads
D'Amore, Salvatore ULg; Miscioscia, Marina ULg; Delvoye, Marie

in Psychology, Community & Heath (2013), 2(2), 87-88

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See detailPrediction of residual stresses by FE simulations on bimetallic work rolls during cooling
Neira Torres, Ingrid ULg; Gilles, Gaëtan ULg; Tchuindjang, Jérôme Tchoufack ULg et al

in Computer Methods in Materials Science (2013), 13(1), 84-91

Bimetallic rolls used in the roughing stands of the Hot Strip Mill require mixed properties as a high wear resistance for the shell material and an enhanced toughness for the core material. The bimetallic ... [more ▼]

Bimetallic rolls used in the roughing stands of the Hot Strip Mill require mixed properties as a high wear resistance for the shell material and an enhanced toughness for the core material. The bimetallic roll studied in this paper is obtained from a vertical spin casting process followed by cooling and subsequent heat treatments. Failure of the compound roll sometimes occurs during the cooling stage of the casting route or later during the thermal treatments. It requires to deeply investigate the thermo mechanical metallurgical interactions generated during cooling and heat treatment in order to find the origin of cracks. For this purpose, a thermo metallurgic mechanical finite element model is used. However these numerical simulations require a high amount of mechanical, thermal and metallurgical parameters. In order to determinate these parameters, a study of available data for estimation of mechanical parameters was performed. Thermo physical parameters were obtained by DTA and DSC methods. Metallurgical characterization by inverse numerical method based on available CCT diagrams was performed to determine the TTT diagrams. First cooling numerical simulations are presented, allowing a rough estimate of residual stresses values and the identification of key parameters for predicting accurate residual stresses by sensitivity analysis. [less ▲]

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See detailFirst retrievals of HCFC-142b from ground-based high resolution FTIR solar observations: application to high altitude Jungfraujoch spectra
Mahieu, Emmanuel ULg; O'Doherty, Simon; Reimann, Stefan et al

in Geophysical Research Abstracts (2013), 15

Hydrofluorocarbons (HCFCs) are the first substitutes to the long-lived ozone depleting halocarbons, in particular the chlorofluorocarbons (CFCs). Given the complete ban of the CFCs by the Montreal ... [more ▼]

Hydrofluorocarbons (HCFCs) are the first substitutes to the long-lived ozone depleting halocarbons, in particular the chlorofluorocarbons (CFCs). Given the complete ban of the CFCs by the Montreal Protocol, its Amendments and Adjustments, HCFCs are on the rise, with current rates of increase substantially larger than at the beginning of the 21st century. HCFC-142b (CH3CClF2) is presently the second most abundant HCFC, after HCFC-22 (CHClF2). It is used in a wide range of applications, including as a blowing foam agent, in refrigeration and air-conditioning. Its concentration will soon reach 25 ppt in the northern hemisphere, with mixing ratios increasing at about 1.1 ppt/yr [Montzka et al., 2011]. The HCFC-142b lifetime is estimated at 18 years. With a global warming potential of 2310 on a 100-yr horizon, this species is also a potent greenhouse gas [Forster et al., 2007]. First space-based retrievals of HCFC-142b have been reported by Dufour et al. [2005]. 17 occultations recorded in 2004 by the Canadian ACE-FTS instrument (Atmospheric Chemistry Experiment – Fourier Transform Spectrometer, onboard SCISAT-1) were analyzed, using two microwindows (1132.5–1135.5 and 1191.5–1195.5 cm-1). In 2009, Rinsland et al. determined the HCFC-142b trend near the tropopause, from the analysis of ACE-FTS observations recorded over the 2004–2008 time period. The spectral region used in this study extended from 903 to 905.5 cm-1. In this contribution, we will present the first HCFC-142b measurements from ground-based high-resolution Fourier Transform Infrared (FTIR) solar spectra. We use observations recorded at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl), with a Bruker 120HR instrument, in the framework of the Network for the Detection of Atmospheric Composition Change (NDACC, visit http://www.ndacc.org). The retrieval of HCFC-142b is very challenging, with simulations indicating only weak absorptions, lower than 1% for low sun spectra and current concentrations. Among the four microwindows tested, the region extending from 900 to 906 cm-1 proved to be the most appropriate, with limited interferences, in particular from water vapor. A total column time series spanning the 2004-2012 time period will be presented, analyzed and critically discussed. After conversion of our total columns to concentrations, we will compare our results with in situ measurements performed in the northern hemisphere by the AGAGE network. [less ▲]

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See detailA new method for computing the derivatives of the mean and amplitude of physiological variables with respect to the parameters of a cardiovascular system model
Pironet, Antoine ULg; Dauby, Pierre ULg; Revie, James A. et al

in Minimally Invasive Therapy & Allied technologies : Official Journal of the Society for Minimally Invasive Therapy (2013), 22

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See detailRisks factors for valvular regurgitations in 3499 equids: a cross-sectional study.
Leroux, Aurélia ULg; Detilleux, Johann ULg; Sandersen, Charlotte ULg et al

in Proceedings of the 2013 ACVIM Forum (2013)

Risk factors for valvular regurgitations (VR) have been suspected in equids, but no extensive epidemiologic study has been performed in a large mixed equine population. Therefore, the aim of this study ... [more ▼]

Risk factors for valvular regurgitations (VR) have been suspected in equids, but no extensive epidemiologic study has been performed in a large mixed equine population. Therefore, the aim of this study was to statistically test risk factors for VR in a large population of equids. Hospital records were reviewed for 3.499 equids, admitted at the internal medicine department of the Liege Equine Teaching Hospital between 1994 and 2011, aged ≥2 years, and which underwent thorough cardiac clinical evaluation. Of this population, 495 cases had ECG and echocardiography performed because of a clinical suspicion of cardiac disease. Chi-square test or logistic regressions (as appropriate) were used to test if breed, gender, age, body weight (BW), and co-existence of various cardiac diseases were risk factors for each VR. Moreover, the risk of development of congestive heart failure (CHF) was tested for each VR. Significance was set at p<0.05. Most of the studied animals were warmbloods, and observed prevalences were 4.4% for mitral regurgitation (MR), 2.1% for aortic regurgitation (AR), 1.7% for tricuspid regurgitation (TR), and 1.0% for pulmonary regurgitation (PR). Significant risk factors were male gender and increasing age for AR (OR=2.03, CI=1.07-4.94), and racehorses breed group and middle-age for TR (OR=4.36; CI=1.10-17.24). No effect of age or BW was demonstrated for MR. MR was the major valvular disease associated with atrial fibrillation (AF), ventricular tachyarrhythmia, PR and CHF. TR was also linked to AF, PR and CHF; but AR was not linked to CHF. In conclusion, several previously suspected risks factors for VR were confirmed statistically in this study and should be taken into account in health and athletic monitoring of horses presenting predisposing factors. [less ▲]

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See detailValence transversities: the collinear extraction
Courtoy, Aurore ULg; Bacchetta, Alessandro; Radici, Marco

in PoS - Proceedings of Science (2013)

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See detailModeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo
Crowet, Jean-Marc ULg; Lins, Laurence ULg; Deshayes, Sébastien et al

in European Biophysics Journal [=EBJ] (2013), 42(S1), 63

CADY is a cell-penetrating peptide spontaneously making non-covalent complexes with short interfering RNAs (siRNAs) in water. Neither the structure of CADY nor that of the complexes is resolved. We have ... [more ▼]

CADY is a cell-penetrating peptide spontaneously making non-covalent complexes with short interfering RNAs (siRNAs) in water. Neither the structure of CADY nor that of the complexes is resolved. We have calculated and analyzed 3D models of CADY and of the non-covalent CADY–siRNA complexes in order to understand their formation and stabilization. Data from the ab initio calculations and molecular dynamics support that, in agreement with the experimental data, CADY is a polymorphic peptide partly helical. We calculated and compared several complexes with peptide/siRNA ratios of up to 40. The initial binding of CADYs is essentially due to the electrostatic interactions of the arginines with siRNA phosphates. Due to a repetitive arginine motif (XLWR(K)), CADYs can adopt multiple positions at the siRNA surface. Nevertheless, several complex properties are common: an average of 14 ± 1 CADYs is required to saturate a siRNA. The 40 CADYs/siRNA that is the optimal ratio for vector stability always corresponds to two layers of CADYs per siRNA and the peptide cage is stabilized by hydrophobic CADY–CADY contacts. The analysis demonstrates that the hydrophobicity, the positive charges and the polymorphism of CADY are mandatory to make stable the CADY–siRNA complexes. [less ▲]

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See detailHydrological and geopedological dynamics of a forested slope
Deraedt, Deborah ULg; Degré, Aurore ULg; Colinet, Gilles ULg

in Geophysical Research Abstracts (2013), 15

Though forested watersheds are really particular in terms of hydrodynamics, most of the hydrological models oversimplify the phenomena involved. More investigations are unavoidable to improve the ... [more ▼]

Though forested watersheds are really particular in terms of hydrodynamics, most of the hydrological models oversimplify the phenomena involved. More investigations are unavoidable to improve the knowledge and the modelling of this environment. Here is the aim of this study. The studied slope is located on the Houille watershed in the West of the Belgian Ardenne (50 1’47”N, 4 53’22”E) on a silty rocky soil. The site is situated under a Douglas fir (Pseudotsuga menziesii (MIRB.) FRANCO) and spruce stand cover (Picea abies (L.) Karst). It is about 160 meters long with a North-West facing slope between 7 and 55%. The goal of the study is : - to characterise the hydrological and pedogeological dynamics along a forested slope, - to compare these dynamics with the tree growth. For the geopedological part of the study, eight pits were dug to describe the soil and take some soil samples used for granulometric, chemical, etc. analysis. We have used geophysical methods (Electrical Resistivity Tomography and Ground Penetrating Radar) to estimate the soil depth. As for the hydrological part of this study, moisture sensors (capacitive and TDR) have been installed in the pits along the slope. A dye tracing test has been performed to underline the preferential flow and the importance of the subsurface flow. Several trees have been equipped with dendrometers and some measures of the LAI and the height of the trees are planned. [less ▲]

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See detailStrunian Rugose and Tabulate corals from Northwestern Turkey
Denayer, Julien ULg

in Document de l'Institut Scientifique, Rabat (2013), 26

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See detailAnalysis of $\alpha_s$ from the realization of quark-hadron duality
Courtoy, Aurore ULg; Liuti, Simonetta

in World Scientific (2013)

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See detailSymmetries in multi-Higgs-doublet models
Ivanov, Igor ULg; Vdovin, Evgeny

in AIP Conference Proceedings (2013)

We report the recent progress in understanding of symmetries which can be implemented in the scalar sector of electroweak symmetry breaking models with several Higgs doublets. In particular we present the ... [more ▼]

We report the recent progress in understanding of symmetries which can be implemented in the scalar sector of electroweak symmetry breaking models with several Higgs doublets. In particular we present the list of finite reparametrization symmetry groups which can appear in the three-Higgs-doublet models. [less ▲]

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See detailInteraction of fengycin with stratum corneum mimicking model membranes: a calorimetry study
Nasir, Mehmet Nail ULg; Eeman, Marc; Olofsson, Gerd et al

in European Biophysics Journal [=EBJ] (2013), 42(S1), 168

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See detailGestion de la reproduction dans les troupeaux bovins laitier
Hanzen, Christian ULg; Rao, Anne-Sophie ULg; Theron, Léonard ULg

in Revue Africaine de Santé et de Productions Animales [=RASPA] (2013)

La décision de la commission européenne de mettre fin en 2015 à la politique des quotas laitiers mise en place en 1984 va vraisemblablement bousculer le paysage laitier européen mais aussi mondial. Plus ... [more ▼]

La décision de la commission européenne de mettre fin en 2015 à la politique des quotas laitiers mise en place en 1984 va vraisemblablement bousculer le paysage laitier européen mais aussi mondial. Plus que jamais les grands pays producteurs (Etats-Unis, Canada, France, Allemagne, Pays-Bas, Irlande, Nouvelle-Zélande) vont dans ce contexte de libéralisation et de globalisation de « l’or blanc » se livrer une concurrence effrénée dans laquelle la majorité des producteurs n’auront que peu ou rien à dire. L’augmentation attendue de la production laitière mondiale (15 milliards de litres par an entre 2010 et 2020) résulte bien entendu de l’augmentation de la population mondiale (3,1 milliards entre 1970 et 2010 auxquels s’ajouteront 2 milliards de plus en 2050) mais également du fait que davantage de personnes en Extrême et Moyen-Orient, en Amérique du Sud et en Afrique du Nord consomment davantage de lait et de produits dérivés. L’enjeu pour la majorité des éleveurs européens ou non va être de réduire les coûts liés à la production laitière en (1) optimisant les ressources alimentaires, (2) en améliorant la santé mammaire, (3) en augmentant la longévité des vaches, (4) en réduisant la fréquence des maladies métaboliques, locomotrices ou infectieuses et (5) en améliorant la fécondité. L’amélioration de la fécondité passe définition oblige par la réduction de l’âge du premier vêlage et de l’intervalle entre vêlages. Par gestion, il faut entendre dans un premier temps la quantification du problème et dans un second l’identification des diverses hypothèses diagnostiques qui en sont responsables. Les facteurs de nature alimentaire, thérapeutique, pathologique ou de gestion susceptibles de modifier l'évolution normale de chaque femelle depuis sa naissance jusqu'au moment de sa réforme sont de nature diverse. Ils concernent l'individu ou le troupeau. Ils sont directement ou indirectement responsables de leur fertilité et/ou de leur fécondité. Leurs effets se manifestent de manière isolée ou synergique. Ils concernent aussi bien les animaux que ceux qui en ont la responsabilité sanitaire ou de gestion. Ils sont de nature anatomique, infectieuse, hormonale, thérapeutique ou zootechnique. Par gestion de la reproduction, il faut entendre une approche épidémiologique, globale de l’infécondité qui en intègre les aspects spécifiques sans négliger pour autant les autres aspects qui ne lui sont pas directement liés. Par gestion de la reproduction, on peut aussi comprendre sa gestion hormonale à savoir le recours à des protocoles thérapeutiques de synchronisation des inséminations et donc des vêlages. L’une et l’autre approche s’inscrive dans le contexte d’une identification systématique des animaux à risque au travers d’un suivi mensuel de reproduction. Ce suivi est la clé de voûte d’une gestion de la reproduction. Au travers d’une démarche hypothético-déductive, la présente communication se propose de - quantifier les performances de reproduction au travers des ses principaux paramètres de fécondité et de fertilité : cette première étape est indispensable pour identifier la présence ou non d’un problème d’infécondité, - passer en revue et de manière aussi synthétique que possible les diverses hypothèses et donc les facteurs de risque responsables d’infécondité - proposer des stratégies curatives ou préventives, anti-infectieuses ou hormonales voire zootechniques pour limiter les conséquences de l’infécondité. [less ▲]

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See detailAltered cartilage phenotype in mice lacking Sirt-1 gene
Gabay, Odile; Zaal, K; Sanchez, Christelle ULg et al

in Osteoarthritis and Cartilage (2013), 21

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See detailIdentifying early Earth microfossils in unsilicified sediments
Javaux, Emmanuelle ULg; Asael, Dan; Bekker, Andrey et al

in Geophysical Research Abstracts (2013), 15

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See detailQUASI-STATIC MECHANICAL BEHAVIOUR OF TI-6AL-4V ALLOY AT ROOM TEMPERATURE
Tuninetti Vásquez, Victor ULg; Gilles, Gaëtan ULg; Milis, Olivier ULg et al

in Complas XII (2013), XII

In order to determine the mechanical behavior of a bulk TA6V alloy, a set of mechanical tests such as shear, compression, tensile monotonic tests, and tensile tests on notched samples are performed. The ... [more ▼]

In order to determine the mechanical behavior of a bulk TA6V alloy, a set of mechanical tests such as shear, compression, tensile monotonic tests, and tensile tests on notched samples are performed. The material is tested at constant strain rate. Full-field optical technique for displacement measurements and strain computation are used for all the experiments. Plastic anisotropy and tension–compression asymmetry are observed. The CPB06 [1] yield criterion adapted for hexagonal close packed (hcp) material is identified. The sensitivity of the material parameters on the identification method as well as the efficiency of the model to predict forces and displacement field are discussed. Validation is done by using Finite Element method (FEM) simulations and 3D Digital Image Correlation (3D-DIC) measurements on specimens with multi-axial stress and strain fields subjected to large deformation. [less ▲]

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See detailGenetics of body energy status of Holstein cows predicted by mid-infrared spectrometry
Bastin, Catherine ULg; Berry, D.; Gengler, Nicolas ULg et al

in Journal of Dairy Science (2013), 96(E-Suppl. 1),

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See detailSterile neutrinos and $R_K$
Vicente, Avelino ULg

in Journal of Physics: Conference Series (2013), 447

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See detailApplication de la résonance magnétique nucléaire (RMN) en toxicologie judiciaire
Denooz, Raphaël ULg; Frederich, Michel ULg; Charlier, Corinne ULg et al

in Acta Clinica Belgica (2013), 68(6), 470

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See detailProcessing of Ti alloys by additive manufacturing: a comparison of the microstructures obtained by laser cladding, selective laser melting and electron beam melting
Reginster, Sylvie ULg; Mertens, Anne ULg; Paydas, Hakan ULg et al

in Materials Science Forum (2013), 765

Additive manufacturing processes such as laser cladding (LC) or selective laser melting (SLM) appear very promising in view of an economic near-net-shape production – and also, in the case of LC, the ... [more ▼]

Additive manufacturing processes such as laser cladding (LC) or selective laser melting (SLM) appear very promising in view of an economic near-net-shape production – and also, in the case of LC, the restoration - of complex and (almost) fully dense parts from Ti alloys. Both techniques involve the melting of a metallic powder with a laser. In the SLM process, the metallic powder is deposited layer by layer in a powder bed and then molten locally according to the desired shape, whereas in LC, the metallic powder is directly projected onto a substrate through a nozzle coaxial with the laser beam. The present research aims at comparing Ti-6Al-4V samples processed by these two techniques with reference samples produced by electron beam melting (EBM), another well established additive manufacturing process (patented by Arcam AB Company) in which a powder bed is molten locally by means of an electron beam. In all three processes, the melt pool undergoes an ultrafast cooling and solidifies very rapidly once the beam has left the area, thus giving rise to strongly out-of-equilibrium microstructures. Yet, each one of these processes also has its own specificities e.g. in terms of scanning strategy and of working atmosphere (low vacuum vs. protective Ar flow). In the present work, the microstructures obtained by these three processes have been compared in details, with a particular attention for characteristics such as porosity, grain size, and the various phases present. Since epitaxial growth of the newly deposited layer on the material previously solidified has been shown [1, 2] to exert a strong influence on the microstructure and on the resulting mechanical properties, great care has been taken to study the microstructural anisotropy associated with each one of the three processes. [less ▲]

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See detailVisean corals from the transverse Jebel Begaa to Gara el Itima (eastern Tafilalt, Morocco)
Aretz, Markus; Denayer, Julien ULg

in Document de l'Institut Scientifique, Rabat (2013), 26

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See detailMeasurement of cerebrospinal fluid albumin in healthy dogs
Ramery, Eve ULg; Girod, Maud ULg; Allerton, Fergus et al

in Veterinary Clinical Pathology (2013)

Background: Measurement of CSF albumin aids diagnosis in human medicine but technical difficulties related to its low CSF concentration prohibit its routine use in veterinary medicine. High-resolution ... [more ▼]

Background: Measurement of CSF albumin aids diagnosis in human medicine but technical difficulties related to its low CSF concentration prohibit its routine use in veterinary medicine. High-resolution electrophoresis (HRE) has been described but often results in non-interpretable integration profiles preventing albumin determination. Fraction quantification using HRE may be more precise after concentration (cHRE) using a membrane microconcentrator technique but has not been evaluated in CSF with total protein levels below 20mg/dL. Immunoturbidimetry is routinely used for human CSF albumin measurement and was recently applied on canine samples with encouraging results. Objective: The purpose of this study was to compare HRE (including the use of a concentration step) and immunoturbidimetric assay for the measurement of albumin levels in normal canine CSF. Methods: 30 CSF specimens from 15 healthy dogs were evaluated. CSF total protein was measured by the pyrogallol red methoda and CSF albumin was determined by HREb (n=15), cHREc (n=30) and immunoturbidimetric assayd (n=30). Validation of the human immunoturbidimetric assay was performed using a purified canine albumin standarde. Results: Mean CSF total protein was 17.5 (range 7-39) mg/dL. HRE integration profiles were non-interpretable in all unconcentrated specimens. However, clear distinction of the major protein fractions was achieved for all cHRE specimens. CSF albumin levels were measureable in 29/30 specimens using immunoturbidimetry. Excellent correlation (Pearson r=0.92, p<0.001) was found between the two techniques. Conclusion: Immunoturbidimetry and cHRE may be used for routine measurement of CSF albumin. [less ▲]

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See detailRisk factors for atrial fibrillation and ventricular tachyarrhythmias in 3499 equids admitted at the liege university equine hospital between 1994 and 2011
Leroux, Aurélia ULg; Detilleux, Johann ULg; Sandersen, Charlotte ULg et al

in Proceedings of the 2013 ECEIM Congress (2013)

Risk factors for atrial fibrillation (AF) and pathological ventricular tachyarrhythmias (VTA) have been suspected in equids, however little epidemiologic data exists. The aim of this study was to ... [more ▼]

Risk factors for atrial fibrillation (AF) and pathological ventricular tachyarrhythmias (VTA) have been suspected in equids, however little epidemiologic data exists. The aim of this study was to determine risk factors for AF and VTA in a large equine population. Case files of 3499 equids admitted to the internal medicine department of the Liege University Equine Teaching Hospital between 1994 and 2011were reviewed. Amongst them, 495 horses with a suspicion of a cardiac abnormality underwent ECG and echocardiography. After calculation of prevalence of AF and VTA, we tested whether breed (chi-square test) or gender, age, body weight (BW) and presence of other cardiac diseases (logistic regressions) were risk factors (significance set at p<0.05). In the studied population, prevalence of AF was high (2.3%), whereas prevalence of VTA was low (0.7%). Warmbloods and standardbreds were significantly overrepresented in AF cases. High BW was a risk factor for AF (OR=3.54; CI=1.67-7.49), whereas age was not. No effect of breed, age or BW was demonstrated for VTA. AF was observed significantly more frequently in horses presenting with moderate to severe mitral regurgitation (MR), tricuspid regurgitation, and pulmonary regurgitation, and VTA was significantly more frequent in horses with MR. Several previously suspected but not statistically demonstrated risk factors of AF were confirmed in this study and horses presenting valvular disease could be at increased risk of developing AF and VTA. [less ▲]

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See detailImportance of LUC and ILUC on the carbon footprint of bioproduct:case of bio-HDPE
Belboom, Sandra ULg; Léonard, Angélique ULg

in International seminar on society and materials (2013)

Due to the depletion of fossil fuels and the increase of greenhouse gas emissions, solutions are needed to replace petrol based products. As a consequence, the number of biobased products developed using ... [more ▼]

Due to the depletion of fossil fuels and the increase of greenhouse gas emissions, solutions are needed to replace petrol based products. As a consequence, the number of biobased products developed using agricultural feedstock is continuously increasing. This study focuses on the carbon footprint of bio-HDPE produced either from Brazilian sugar cane or Belgian sugar beet. The goal of this study is to compare the carbon footprint of bio-HDPE with the fossil one, taking into account the effect of land use change. Common boundaries of the agricultural systems comprise the cultivation step for both crops, i.e. sugar cane and sugar beet, with all associated energy and fertilizer consumptions, the transportation step from field to the industrial plant, the sugar crops transformation into hydrate bioethanol, the by-products valorisation, the dehydration and polymerization steps and the HDPE incineration as end of life issue. Fossil scenario includes the production of ethylene, its polymerization and its incineration. When comparing the entire life cycle of bio and fossil HDPE, the GHG emissions are lower for the biobased product which is the willing effect. This result is only valid if no Land Use Change (LUC) or Indirect Land Use Change (ILUC) effect appears. To assess the environmental impact of the deforestation or of the transformation of a pasture into a field, the EC-Guidelines from the European Union were used in order to calculate the CO2 emissions depending on several parameters. For sugar cane, LUC consists in the transformation of pastures into fields in the region of Sao Paulo in Brazil. Three scenarios can be developed based on different agricultural practices for pasture and field (tillage and fertilizers inputs): the best, the worst and the average. The best case leads to a supplementary environmental gain. The worst and average achieve additional emissions. A payback time, considering the time needed to find again an environmental gain compared to the fossil counterpart, was calculated for the average scenario which is equal to 12 years. The ILUC effect for sugar cane is assumed to be deforestation due to the transformation of forest into pasture induced by the previous LUC effect. The rate of deforestation can vary between 16% or 100% depending on used statistics and leads to a payback time of respectively 26 and 101 years. For sugar beet, no LUC is considered. Indeed, no land expansion is available in Belgium due to small available areas. In the case of an increase of bioplastics production, Belgium should import sugar beet from neighboring countries which can induce ILUC. In this study, sugar beet is assumed to be provided by the Netherlands on pastures previously transformed into fields. The average scenario implies a payback time of 8 years. This study permits to highlight the importance of LUC and ILUC especially for energetic crops dedicated to replace fossil products. This effect can reverse expected results and induce long payback times. [less ▲]

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See detailInfluence of lignin in Reticulitermes santonensis: symbiotic interations investigated through proteomics
Bauwens, Julien ULg; Tarayre, Cédric ULg; Brasseur, Catherine ULg et al

in Symbiosis (2013)

The gut of lower termites is populated by numerous microbial species belonging to prokaryotes, fungi, yeasts and protists. These micro-organisms are organized in a complex symbiotic system, interacting ... [more ▼]

The gut of lower termites is populated by numerous microbial species belonging to prokaryotes, fungi, yeasts and protists. These micro-organisms are organized in a complex symbiotic system, interacting together and with the insect host. Their likely ability to degrade ligno-cellulosic compounds could lead to improvements in second generation biofuels production. Lignin elimination represents a critical point as this polymer significantly interferes with industrial process of cellulose. Although host produces its own lignin-degrading enzymes, some symbionts may participate in digestion of lignin and its degradation products in termite gut. Here, we compared gut proteomes from R. santonensis after rearing on artificial diets composed of cellulose with and without lignin. The effect of lignin in artificial diets on different parts of the digestive tract was compared through liquid chromatography associated with tandem mass spectrometry (LC-MS/MS) experiments. Enzymatic assays were performed to characterize activities present in R. santonensis digestive tract after feeding on artificial diets. Microscopic observations of microbial communities provided some information on population balances after feeding experiment. [less ▲]

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See detailExtension of the Liège Intra Nuclear Cascade model to light ion-induced collisions for medical and space applications
Leray, S.; Mancusi, D.; Kaitaniemi, P. et al

in Journal of Physics: Conference Series (2013), 420

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See detailCorrelation between RNA and protein levels in a large european series from the LYSA
Bossard, C.; Dobay, M.P.; Lamant, L. et al

in Hematological Oncology (2013), 31 Suppl.1

Introduction: CD22 is expressed on most B-non-Hodgkin lymphomas (NHL); inotuzumab ozogamicin (INO) is an anti-CD22 antibody conjugated to calicheamicin. This study evaluated the safety and tolerability of ... [more ▼]

Introduction: CD22 is expressed on most B-non-Hodgkin lymphomas (NHL); inotuzumab ozogamicin (INO) is an anti-CD22 antibody conjugated to calicheamicin. This study evaluated the safety and tolerability of INO plus R-CVP in patients (pts) with relapsed/refractory CD22+ B-NHL. Efficacy data were also collected. Methods: Part 1 of this open-label study identified a maximum tolerated dose (MTD) of INO 0.8mg/m,2 on day 2 plus R-CVP (rituximab 375mg/m,2 cyclophosphamide 750mg/m,2 and vincristine 1.4mg/m,2 on day 1; prednisone 40mg/m,2 on days 1-5) every 21 days. Subsequently, pts were enrolled in the MTD confirmation cohort (part 2, n = 10), which required a dose-limiting toxicity rate of <33% in cycle 1 and <4 pts discontinuing prior to cycle 3 due to an adverse event (AE) in the MTD expansion cohort (part 3, n = 22), which explored preliminary activity. Results: Parts 2 and 3 enrolled 32 pts: 16 pts with diffuse large B-cell lymphoma, 15 with follicular lymphoma and one with mantle cell lymphoma. Median age was 64.5 years (range 44-81 years); 34% of pts had 1 prior regimen, 34% had 2, 28% had ≥3 and 3% had none (median 2; range 0-6).Median treatment duration was five cycles (range 1-6). Part 2 confirmed the MTD as standard dose R-CVP plus INO 0.8mg/m,2; 2/10 pts had a dose-limiting toxicity (grade 3 increased ALT/AST, grade 4 neutropenia requiring G-CSF). One pt discontinued because of an AE prior to cycle 3. Common treatment-related AEs were thrombocytopenia (78%), neutropenia (66%), fatigue (50%), leukopenia (50%), nausea (41%) and lymphopenia (38%); common grade 3/4 AEs were neutropenia (63%), thrombocytopenia (53%), leukopenia (38%) and lymphopenia (31%). There was one case of treatment-related fatal pneumonia with grade 4 neutropenia. Ten pts discontinued treatment due to AEs; thrombocytopenia/delayed platelet recovery was the leading cause (grade 1/2, n = 6; grade 3/4, n = 3). Objective response rate (ORR) was 77% (n = 24/31 evaluable pts), including 26% (n=8/31) with complete response (CR); three pts had stable disease. Of the pts with follicular lymphoma, ORR was 100% (n = 15/15), including seven pts with CR. Of the pts with diffuse large B-cell lymphoma, ORR was 60% (n = 9/16), including one pt with CR. Conclusions: Results suggest that INOplus R-CVP has acceptable toxicity and promising activity in relapsed/refractory CD22+ B-NHL. The most common grade 3/4 AEs were hematologic. Follow-up for progression-free and overall survival is ongoing. [less ▲]

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See detailDetecting correlated di-hadron pairs: about the extraction of transversity and beyond
Radici, Marco; Bacchetta, Alessandro; Courtoy, Aurore ULg

in World Scientific (2013)

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See detailThe Enhancement of Secondary Succession by Western Lowland Gorillas (Gorilla gorilla gorilla) in a Moist Tropical Forest of Southeast Cameroon
Petre, Charles-Albert ULg; Haurez, Barbara ULg; Tagg, Nikki et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84

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See detailPrevalence of vitamin D inadequacy in European postmenopausal women aged over 80 years
Bruyère, Olivier ULg; Slomian, Justine ULg; Beaudart, Charlotte ULg et al

in European Geriatric Medicine (2013), 4(S1), 13-14

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See detailPrognostic value of FDG PET/CT in patients with lung tumors treated by Cyberknife.
LOVINFOSSE, Pierre ULg; JANVARY, Zsolt Levente ULg; JANSEN, Nicolas ULg et al

in Journal of Nuclear Medicine (The) (2013), 54(SUPPL), 567

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See detailComparison of Immune Reconstitution after Hematopoietic Stem Cell Transplantation with Flu-TBI versus TLI-ATG Conditioning
Hannon, Muriel ULg; Humblet-Baron, S.; Graux, C. et al

in Belgian Journal of Hematology (2013), Abstracts book(Supplement of 28th General Meeting of the Belgian Hematological Society), 38

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See detailBlood lead, urinary lead, urinary δ-aminolevulinic acid and urinary porphyrins levels among people living in kinshasa, D.R. Congo : a pilot biomonitoring study
Mputu Malolo, Corneille-Liévin; Ndelo di Phanzu, Josaphat; Marini Djang'Eing'A, Roland ULg et al

in Acta Clinica Belgica (2013), 68(6), 475

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See detailPotential of mid-infrared spectrum of milk to detect changes in the physiological status of dairy cows
Laine, Aurélie ULg; Goubau, Amaury; Hammami, Hedi ULg et al

in Journal of Dairy Science (2013)

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See detailFinal analysis of overall survival for the Phase III CONFIRM trial: fulvestrant 500 mg versus 250 mg
DI LEO, Angelo; JERUSALEM, Guy ULg; PETRUZELKA, Lubos et al

in Cancer Research. Supplement (2012, December 15), 72(24), 1-4

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See detailDiscriminant BOLD Activation Patterns during Mental Imagery in Parkinson’s Disease
Schrouff, Jessica ULg; Cremers, Julien ULg; D'Ostilio, Kevin ULg et al

in Proceedings of MLINI 2012 (2012, December 07)

Using machine learning based models in clinical applications has become current practice and can prove useful to provide information at the subject’s level, such as predicting an (early) diagnosis or ... [more ▼]

Using machine learning based models in clinical applications has become current practice and can prove useful to provide information at the subject’s level, such as predicting an (early) diagnosis or monitoring the evolution of a disease. However, the performance of these models depends on the choice of a biomarker to detect the presence or absence of a disease. Choosing a biomarker is not straightforward, especially in the case of Parkinson’s disease when compared to healthy subjects. In the present work, we investigated the mental imagery of gait as a biomarker of Parkinson’s disease and showed that the signal in the mesencephalic locomotor region during the mental imagery of gait at a comfortable pace can discriminate significantly between idiopathic Parkinson’s disease patients and healthy subjects. Although there is room for improvement, the results of this preliminary study are promising. [less ▲]

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See detailInnovative Surface Plasmon Resonance biosensing architectures
desfours, Caroline; Hastanin, Juriy ULg; Drucbert, Anne-Sophie et al

in International Conference on Fibre Optics and Photonics (2012, December)

Surface Plasmons Resonance (SPR) architectures involving multi-wavelength interrogation are an attractive alternative for droplet biosensing. We present our results for in situ measurements of biological ... [more ▼]

Surface Plasmons Resonance (SPR) architectures involving multi-wavelength interrogation are an attractive alternative for droplet biosensing. We present our results for in situ measurements of biological molecules with a two-wavelength sensor and a SPR Coupler- Disperser spectroscopic sensor. [less ▲]

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See detailEvaluation d'un protocole de prise en charge nutritionnelle interdisciplinaire chez des patients brulés
MALHERBE, Christian ULg; VERBRUGGE, Anne-Marie ULg; MAGNETTE, André ULg et al

in Nutrition Clinique et Metabolisme (2012, December), 26-Supp1

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See detailNon-thermal radiation from a runaway early-type star
del Valle, M.; Romero, G.E.; De Becker, Michaël ULg

in AIP Conference Proceedings (2012, December), 1505

HD 195592 is an O-type supergiant star, known as a well-established runaway. Recently, a Fermi γ-ray source (2FGL J2030.7+4417) with a position compatible with that of HD 195592 has been reported. Our ... [more ▼]

HD 195592 is an O-type supergiant star, known as a well-established runaway. Recently, a Fermi γ-ray source (2FGL J2030.7+4417) with a position compatible with that of HD 195592 has been reported. Our goal is to explore a scenario where HD 195592 is the counterpart of the Fermi γ-ray source. The high-energy emission would be inverse Compton radiation produced in the bowshock of the runaway star. We calculate relativistic particle energy losses and the resulting radiation from the bowshock of HD 195592 and show that the latter is compatible with the detected γ-ray emission. We conclude that the Fermi source 2FGL J2030.7+4417 might be produced, under some energetic assumptions, by inverse Compton up-scattering of infrared photons from locally heated dust. HD 195592 might therefore be the very first object detected belonging to the category of γ-ray emitting runaway massive stars, whose existence has been recently predicted. [less ▲]

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See detailUne étude de la vulnérabilité cognitive des parents au premier degré de patients schizophrènes
Wagener, Aurélie ULg; Duke, Géraldine; Xhenseval, Laure et al

in Revue Francophone de Clinique Comportementale et Cognitive (2012, December), XVII(4), 53

Schizophrenic patients and their first-degree relatives suffer from cognitive deficits in different area (memory, executive, attentional and language functions) which allows us to consider these deficits ... [more ▼]

Schizophrenic patients and their first-degree relatives suffer from cognitive deficits in different area (memory, executive, attentional and language functions) which allows us to consider these deficits as endophenotypes of schizophrenia. Schizophrenic patients also suffer from a lack of autobiographical memory and instability of identity: our study aims to determine whether this deficit and this instability are endophenotypes of schizophrenia. In order to reach this objective, we evaluated first-degree relatives. The results show that first-degree relatives suffer from cognitive deficits but, contrary to our hypotheses, not any deficit of specificity or instability of identity have been highlighted among these parents. [less ▲]

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See detail(Pré)textes : perspective didactique sur le dépeçage des textes littéraires à des fins d'exemplification
Van Beveren, Julien ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (2012, December), 4

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See detailDynamic simulations of solar combisystems integrating a seasonal sorption storage: Influence of the combisystem configuration
Hennaut, Samuel ULg; Thomas, Sébastien ULg; Davin, Elisabeth ULg et al

in Strojarstvo: Journal for Theory and Application in Mechanical Engineering (2012, December), 54(6), 433-440

This paper focuses on the sizing of solar combisystems with adsorption seasonal storage to target autonomous solar space heating. Two main configurations of the combisystem are simulated, including one or ... [more ▼]

This paper focuses on the sizing of solar combisystems with adsorption seasonal storage to target autonomous solar space heating. Two main configurations of the combisystem are simulated, including one or two tanks. The influence of the seasonal storage on the sizing of the tanks is also discussed. Results show that performances of the system with two tanks are better (2 to 4 % with seasonal storage) but some improvements should be possible for the single tank configuration. The sizing of the sensible storage is nearly independent of the solar collectors area if there is a seasonal storage. The sensible storage size increase with the collectors area without adsorption storage. The analysis is conducted in simulation using the TRNSYS program. [less ▲]

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See detailUse of medium without reducing agent for in vitro fermentation studies by bacteria isolated from pig intestine
POELAERT, Christine ULg; Boudry, Christelle ULg; Portetelle, Daniel ULg et al

in Journal of Animal Science (2012, December), 90(Supplement 4), 387-389

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See detailPotentiel de dispersion du sanglier et historique de la colonisation de la plaine agricole
Morelle, Kevin ULg; Prévot, Céline

in Forêt Wallonne (2012, December), 121

Les populations de sangliers augmentent en nombre et étendent leur aire de répartition un peu partout en Europe. En Wallonie, la population de sangliers a quadruplé en 30 ans. Plusieurs études se sont ... [more ▼]

Les populations de sangliers augmentent en nombre et étendent leur aire de répartition un peu partout en Europe. En Wallonie, la population de sangliers a quadruplé en 30 ans. Plusieurs études se sont penchées sur le sujet et les raisons de cette augmentation concernent souvent l’influence du climat. Grâce aux différents suivis réalisés par le DEMNA, les déplacements au sein des populations de sangliers sont mieux compris. L’article se penche d’abord sur le potentiel de dispersion du sanglier en se basant sur les données de bagage de marcassins. Deux variables sont analysées : la distance parcourue dans le cadre de la dispersion natale (mouvement à sens unique à partir du site de naissance d’un individu jusqu’à son site de première reproduction) et le taux de cette dispersion natale. Quelques résultats provenant d’une étude génétique sont également présentés. Le génotypage de 1153 sangliers répartis sur l’ensemble de la Wallonie a mis en évidence quatre sous-populations génétiquement homogènes. Parallèlement à l’augmentation de la taille de ses populations, le sanglier a vu son aire de distribution s’accroître en Wallonie. Un suivi par enquête a été réalisé auprès des conseils cynégétiques et des agents du DNF pour mieux comprendre l’expansion géographique observée. Une première phase de l’enquête visait à retracer l’expansion géographique du sanglier en Wallonie. La seconde phase consistait à réaliser un état des lieux sur la situation actuelle de la distribution du sanglier en périphérie du sillon Sambre-et-Meuse. [less ▲]

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See detailMeasurement of serum albumin by protein electrophoresis and bromocresol green methods in canine and equine patients
Ramery, Eve ULg; Bureau, Fabrice ULg

in Veterinary Clinical Pathology (2012, December), 41(4), 5

Background: Bromocresol green method (BCG) is routinely used in veterinary laboratories to measure albumin. A good agreement between BCG and electrophoresis (SPE) in healthy domestic animals is reported ... [more ▼]

Background: Bromocresol green method (BCG) is routinely used in veterinary laboratories to measure albumin. A good agreement between BCG and electrophoresis (SPE) in healthy domestic animals is reported. However, in human medicine, at low albumin and high globulin concentrations, BCG also binds to α- and β-globulins fractions. Surprisingly, there is no recent literature evaluating the BCG method in diseased domestic animals. Objective: The purpose of the present study was therefore to compare the serum albumin values obtained by SPE and BCG in canine and equine patients. Methods: Albumin measured by BCG and SPE was compared in the serum from 30 canine and 30 equine patients. Results: Good correlation was found (Spearman´s rho rs = 0.91 in dogs and 0.84 in horses). However, Altman and Bland analysis of results showed a positive bias of BCG with SPE (3.41 g/l in horses and 0.41 g/l in dogs) that increased when only hypoalbuminemic patients were considered (4.17 g/l in horses and 1.31 g/l in dogs). Conclusion: Results confirm that, despite good correlation, BCG method tends to overestimate albumin, especially in hypoalbuminemic patients. This is particularly evident in horses. [less ▲]

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See detailPatterns of Clinical Management and Resource Utilisation for Postmenopausal Hormone-Receptor-Positive HER2-Negative (HR+ HER2-) Advanced Breast Cancer (BC) in Europe
ANDRE, Fabrice; MARINSEK, Nina; RICCI, Jean-François et al

in Value in Health (2012, November), 15(7), 419

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See detailCouplage des modèles numériques SWAT et FeFlow pour l'étude des flux de nitrate à l'échelle d'un bassin versant agricole posé sur un aquifère sableux. Calibrage, validation et test de scénarios pour l'évaluation de pratiques agricoles plus durables en terme de gestion de l'azote
Vandenberghe, Christophe ULg; Deneufbourg, Mathieu ULg; Gaule, David et al

in Bulletin du groupe francophone Humidimétrie et Transferts en milieux poreux (2012, November), 58

Quatre prises d’eau exploitées à Arquennes (Belgique) sont contaminées par le nitrate. Leurs bassins d’alimentation sont situés en zone agricole caractérisée par un sol limoneux sur un aquifère sableux ... [more ▼]

Quatre prises d’eau exploitées à Arquennes (Belgique) sont contaminées par le nitrate. Leurs bassins d’alimentation sont situés en zone agricole caractérisée par un sol limoneux sur un aquifère sableux. Depuis 2004, ces bassins servent de site pilote dans le cadre de l’évaluation du Programme de Gestion Durable de l’Azote (PGDA), transposition de la Directive « Nitrates » en droit wallon. Les modèles numériques SWAT et FEFLOW ont permis de simuler les flux d’eau et de nitrate depuis la surface jusqu’aux galeries. Après calibrage et validation des modèles (sur la base d’une caractérisation du sol et du sous-sol et de traçages en milieux saturé et non saturé), plusieurs scénarios de pratiques agricoles ont été simulés afin de prédire l’évolution qualitative des eaux. L’expérience d’Arquennes a démontré que le recours au couplage SWAT / FEFLOW permet de proposer des solutions environnementales réalistes pour atteindre les objectifs fixés par la DCE. [less ▲]

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See detailWhat is the potential increase of the heart graft pool by cardiac donation after circulatory death?
NOTERDAEME, Timothée; NELLESSEN, Eric ULg; HANS, Marie-France ULg et al

in Transplantation (2012, November), 94

Background: Heart transplantation remains to date the only definite treatment option for end-stage heart diseases. Currently only heart procured from brain death (DBD) donors are used. Combined with an ... [more ▼]

Background: Heart transplantation remains to date the only definite treatment option for end-stage heart diseases. Currently only heart procured from brain death (DBD) donors are used. Combined with an increasing demand, the constant heart graft shortage leads to an increase of deaths on cardiac transplantation waiting lists. The use of hearts procured after donation after circulatory death (DCD) could help to partly decrease the heart graft shortage. The aim of this study was to evaluate the potential increase of heart graft pool by development of DCD heart transplantation. Methods: The authors retrospectively reviewed their local donor database for the period 2006-2011, and screened the complete controlled DCD donor population for potential heart donors, using the same criteria as for DBD heart transplantation. The acceptable warm ischemic time (WIT) was limited to 30min from life support withdrawal to aortic cannulation. Results: During the analyzed timespan, 177 DBD and 70 DCD were effectively performed. From the 177 DBD, a total of 70 (39.5%) hearts were procured and transplanted locally or in another center. Out of the 70 DCD, 8 (11%) donors fulfilled the criteria for heart graft procurement and had a WIT of less than 30 minutes. During the same period, 82 patients were newly listed for heart transplantation, of which 53 were transplanted, 20 died or were unlisted, and 9 were still awaiting transplantation. Conclusions: Based on our database and a WIT of less than 30min, it could be estimated that 11% of the DCD might be heart graft donors, representing a 11% increase in heart graft procurement, as well as potential reduction of the deaths on the waiting list by 40%. [less ▲]

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See detailVocal Impact of a Prolonged Reading Task in Dysphonic versus Normophonic Female Teachers
Remacle, Angélique ULg; Morsomme, Dominique ULg; Berrué, Elise et al

in Journal of Voice (2012, November), 26(6), 8201-82013

OBJECTIVES: This study evaluates the impact on voice of a 2-hour reading task between 70-75 dB(A) in 16 normophonic and 16 dysphonic female teachers with vocal nodules. METHODS: Objective measurements ... [more ▼]

OBJECTIVES: This study evaluates the impact on voice of a 2-hour reading task between 70-75 dB(A) in 16 normophonic and 16 dysphonic female teachers with vocal nodules. METHODS: Objective measurements (acoustic analysis, voice range measurements, aerodynamic measurements) and subjective self-ratings were collected before the task and every 30 minutes during the reading to determine the voice evolution in both groups. RESULTS: Fundamental frequency, lowest frequency, highest frequency (F-High), highest intensity and intensity range increase through the reading, whereas Shimmer decreases. Maximum phonation time decreases after 30 minutes. Estimated subglottal pressure (ESP) and sound pressure level increase during the first hour. Afterwards, ESP decreases. Self-ratings worsen through time. When comparing the normophonic and the dysphonic teachers, self-ratings reveal more complaints in the dysphonic group. Few differences in objective measurements are found between both groups: normophonic teachers show lower ESP, higher F-High and greater frequency range. CONCLUSIONS: Frequency modifications from acoustic analysis and voice range measurements suggest an increased laryngeal tension during vocal load, while subjects perceive a worsening of voice. Aerodynamic parameters depict first a deterioration of voice efficiency and then an adaptation to the prolonged reading. The comparison between both groups shows a discrepancy between objective measurements and self-ratings, suggesting that both approaches are necessary to have a complete view of vocal load effects. Surprisingly, both groups behave similarly through vocal load, without more or quicker deterioration of voice in the dysphonic group. [less ▲]

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See detailEvaluation de l’impact de la filiere de production porcine sur les caractéristiques des jambons de l’IGP (Indication Géographique Protégée) Jambon d’Ardenne
Dzaomuho-Lenieregue, Phidias ULg; Eloundou Mballa, Pierre ULg; Sindic, Marianne ULg et al

in Viandes et Produits Carnés (2012, November), Hors-Série

The aim of this study is to evaluate the influence of pork production sector on technological behavior of raw material, properties of the ham final product and consumer preferences. An experimental ... [more ▼]

The aim of this study is to evaluate the influence of pork production sector on technological behavior of raw material, properties of the ham final product and consumer preferences. An experimental manufacturing assay of Ardenne Ham has been conducted for this purpose. Results show few incidence of pork production conditions on technological properties and chemical or sensory characteristics of hams. The preference tests, carried out with a sensory panel using several criteria, showed that consumers were able to distinguish two groups of hams, according to their fat content. They have a preference for lower-fat ham from one of the studied sectors. Method of multicriteria decision shows no overall preference for one of the submitted ham. [less ▲]

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See detailHighly excited states of baryons in large Nc QCD
Matagne, Nicolas; Stancu, Floarea ULg

in Bled Workshops in Physics (2012, November), 13(1), 47-53

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See detailDoes processing speed protect from age-related decline in cognitive control?
Manard, Marine ULg; Carabin, Delphine; Collette, Fabienne ULg

in Frontiers in Human Neuroscience (2012, October 27)

Age-related difficulties have been reported on proactive control whereas reactive control seems to remain intact (Braver, Gray, & Burgess, 2007; Braver, 2012). This study investigated the potential ... [more ▼]

Age-related difficulties have been reported on proactive control whereas reactive control seems to remain intact (Braver, Gray, & Burgess, 2007; Braver, 2012). This study investigated the potential influence of speed of processing abilities on the age-related decline in proactive control. We used a working memory recognition paradigm involving proactive or reactive cognitive control by manipulating the interference level across items. 80 young adults (18-29 years old) and 80 healthy older adults (60-89 years old) were included. The main results revealed significant effects of age on sensitivity to interference. As expected, reactive control performance remained intact with aging (similar interference effect in the two groups). In contrast, we observed a larger interference effect in the proactive condition in aging. Finally, when the groups are matched according to their processing speed (assessed by the Code task of the WAIS III, with both younger and older adults having a score comprised between 60 and 93), the effect of age on sensitivity to interference disappeared. In other words, when younger and older adults had similar speed of processing abilities, no age-related proactive control decline was observed. In conclusion, beyond the fact that this study confirms the selective age-related decline in proactive control, it also indicates that speed of processing, a measure considered as reflecting the integrity of cognitive functioning during aging (Salthouse, 1996), influences the efficiency of proactive control in that population. [less ▲]

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