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See detailModulation of the biological action of bovine growth hormone by passive immunization in hypophysectomized rat.
Jacqmin, S.; Vleurick, L.; Renaville, Robert ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(1),

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See detailRuthenium-based catalysts for the ring-opening metathesis polymerization (ROMP) of functionalized cyclic olefins
Delaude, Lionel ULg; Jan, Dominique; Simal, François et al

in Macromolecular Symposia (2000), 153

Recent developments in Ring-Opening Metathesis Polymerization (and copolymerization) of functionalized cycloolefins with well-defined ruthenium-based initiators are summarized and illustrated with ... [more ▼]

Recent developments in Ring-Opening Metathesis Polymerization (and copolymerization) of functionalized cycloolefins with well-defined ruthenium-based initiators are summarized and illustrated with synthesis of graft copolymers, telechelic and liquid crystalline polymers, glycopolymers and unsaturated ester-functionalized oligomers. [less ▲]

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See detailExploration de l'effet de simple exposition dans la maladie d'Alzheimer
Willems, Sylvie ULg; Adam, Stéphane ULg; Van der Linden, Martial

in Revue de Neuropsychologie (1999, December 03), 9

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See detailActive deformation along the southern front of the Tianshan Mountains (China)
Hubert, Aurelia ULg; Suppe, J; Wang, Xin et al

in EOS (AGU abstract) (1999, December), 79

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See detailSeismic hazard in the Sea of Marmara Following the Izmit Earthquake
King, G.C.P.; Hubert, Aurelia ULg; Barka, A et al

in EOS : Transactions, American Geophysical Union (1999, December), 79

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See detailTribologie en oxygène liquide
Bozet, Jean-Luc ULg; Bozet, Jean-Luc ULg; Gras, R. et al

in Matériaux et techniques ”, SIRPE, numéro hors série, 38èmes Journées du cercle d’études des métaux (1999, December)

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See detailIntérêt d'une procédure de rappel indicé à 48 items dans le diagnostic précoce de la maladie d'Alzheimer
Ivanoiu, Adrian; Adam, Stéphane ULg; Bechet, Sophie et al

in Revue Neurologique (1999, October 01), 155(Supplément 3), 63-64

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See detail18 kyr, 120 kyr & 5 Myr shortening rates along the front of the southern Tianshan Mountains (China),
Hubert, Aurelia ULg; Suppe, J; Wang, Xin et al

in Geological Society of America - Abstracts with Programs (1999, October), 31(7),

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See detailEndurance training versus combined strength and endurance training in leisure-time cyclists
Weiler, B.; Urhausen, A.; Dahm, C. et al

in International Journal of Sports Medicine (1999, October), 20

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See detailFar ultraviolet Observations of Jovian low latitude regions with HST/STIS
Gustin, Jacques ULg; Grodent, Denis ULg; Gérard, Jean-Claude ULg et al

in Bulletin of the American Astronomical Society (1999, September 01), 30(11),

Far ultraviolet observations of the Jovian disk were made at low and mid-latitudes with FUV MAMA/STIS on board HST in January 1999 both in the imaging and spectroscopic modes. An image was obtained with ... [more ▼]

Far ultraviolet observations of the Jovian disk were made at low and mid-latitudes with FUV MAMA/STIS on board HST in January 1999 both in the imaging and spectroscopic modes. An image was obtained with the Lyalpha filter in the hydrogen bulge region for comparison with the expected Lyman-alpha brightness distribution for Ly-alpha resonance scattering. Other images in the 1200-1700 { Angstroms} region show band structures parallel to the equator with fading contrast toward the center and the limb. Spectroscopic observations were made in the 1200-1700 { Angstroms} (G140L) and 1245-1298 { Angstroms} (G140M) regions at ~ 5 { Angstroms} resolution to map the H_2 airglow and the UV absorbents along the STIS slit. Preliminary results indicate that a C_2H_2 absorption signature is clearly observed in the solar ultraviolet reflected spectrum. The ethylene absorption may be mapped to derive variations of the acetylene abundance. The H_2 FUV airglow shows both the fluorescence and the electron impact components. Its spatial variation is described and compared with the expected airglow distribution. We acknowledge funding by NASA and by the PRODEX program of the European space agency. [less ▲]

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See detailThe complex injuries produced by percutaneous injection of fluids under very high pressure
RADERMECKER, Régis ULg; Thiry, A.; Beaujean, M.

in Journal of Vascular Diseases (1999, September), 11

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See detailEffects of training on delayed onset muscle soreness following isokinetic eccentric exercise
Croisier, Jean-Louis ULg; Camus, Gérard; Ledent, M. et al

in Archives of Physiology & Biochemistry (1999, September), 107(suppl september 1999), 101

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See detailGravity Score and Shock Score as an Aid to dertemine the prognosis in Equine Surgical Colic Cases
Grulke, Sigrid ULg; Olle, Enrice; Detilleux, Johann ULg et al

in Veterinary Surgery : The Official Journal of the American College of Veterinary Surgeons (1999, July)

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See detailWave reflection in the three element WindKessel model
Gommes, Cédric ULg

in Medical & Biological Engineering & Computing (1999, June), 37

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See detailAmorçage perceptif pour du matériel non familier dans la maladie d’Alzheimer : Rôle de l’encodage
Ergis, Anne-Marie; Gierski, F.; Adam, Stéphane ULg et al

in Revue de Neuropsychologie (1999, May 28), 9

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See detailAdvantages of iterative OSEM reconstruction over filtered backprojection in bone SPET
Blocklet, Didier; Seret, Alain ULg; Popa, N. et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1999, May), 40(5), 303

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See detailThe propagation processes of the North Anatolian fault and the Messinian Crisis of the Mediterranean
Armijo, R; Meyer, B; Hubert, Aurelia ULg et al

in Journal of Conference (EUG abstracts) (1999, April), 4

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See detailCongrès SASRO 1999
COUCKE, Philippe ULg

in Strahlentherapie und Onkologie (1999, March)

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See detailDevelopment of a new rat model of fulminant hepatic failure
Detry, Olivier ULg; Gaspard, Yves; Defraigne, Jean-Olivier ULg et al

in Acta Gastro-Enterologica Belgica (1999, January), 62(1), 43

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See detailSurgical management of hepatic cystic echinococcosis
Detry, Olivier ULg; Kanakou, A.; Honoré, Pierre ULg et al

in Acta Gastro-Enterologica Belgica (1999, January), 62(1), 64

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See detailResults of liver transplantation in adults: our experience
Honoré, Pierre ULg; Detry, Olivier ULg; Meurisse, Michel ULg et al

in Acta Gastro-Enterologica Belgica (1999, January), 62(1), 69

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See detailEvaluation of the homocysteine assay on the Abbott IMx
Chapelle, Jean-Paul ULg; Lutteri, Laurence ULg; Gielen, J.

in Clinical Chemistry (1999), 45(6), 134

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See detailSyndrome de Down et entraînement à la mise en œuvre de l’autorépétition active
Frenkel, Stéphanie ULg; Bourdin, Béatrice; Vandromme, Luc

in Le Journal des Psychologues : Le Cahier des Jeunes Chercheurs en Psychologie (1999)

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See detailAre CAB gene expression and flowering under the control of the same clock in Lolium temulentum Ceres ?
Hustin, Cécile; Bernier, Georges ULg; Périlleux, Claire ULg

in Biological Rhythm Research (1999), 30

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See detailHottest pixel analysis: Useful value or statistical artifact ?
DUARTE, P.; HUSTINX, Roland ULg; COUTURIER, O. et al

in Journal of Nuclear Medicine (The) (1999), 40

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See detailIn vivo studies of p-[18F]MPPF metabolites in human.
Damhaut, Ph.; Plenevaux, Alain ULg; Lemaire, Christian ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1999), 42

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See detailThe synthesis of 6-[18F]fluoro-L-dopa by chiral catalytic phase-transfer alkylation.
Lemaire, Christian ULg; Guillouet, S.; Plenevaux, Alain ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1999), 42

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See detailp-[18F]MPPF, a fluoro analog of WAY-100635 for visualisation of 5-HT1A receptors in cat.
Le Bars, D.; Ginovart, N.; Hassoun, W. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1999), 42

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See detail5-HT1A Receptors visualization with p-[18F]MPPF in healthy volunteers.
Plenevaux, Alain ULg; Lemaire, Christian ULg; Salmon, Eric ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1999), 42

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See detailEconomie sociale et Innovation socio-économique dans le secteur de l’élevage en Wallonie. .
Collet, Eric; Stassart, Pierre M ULg

in Cahiers du CIRIEC (1999)

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See detailEthanol neurotoxicity: from basic science to clinical reality
De Witte, Philippe; Ward, Roberta; Dahchour, Abdelkhader et al

in Alcohol & Alcoholism (1999), 34

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See detailComparison of four markers of bone resorption as diagnostic or monitoring tools in postmenopausal osteoporosis
Reginster, Jean-Yves ULg; Taquet, AN; Christiansen, C et al

in Arthritis and Rheumatism (1999), 42(S1), 291

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See detailClinical performance of the C-PET camera.
SMITH, RJ.; HUSTINX, Roland ULg; ADAM, LE. et al

in Journal of Nuclear Medicine (The) (1999), 40

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See detailDual time-point FDG-PET imaging to distinguish tumor from normal and inflammatory sites in the head and neck.
HUSTINX, Roland ULg; SMITH, RJ.; ROSENTHAL, DI. et al

in Journal of Nuclear Medicine (The) (1999), 40

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See detailA dominant negative mutation in the P2X1 receptor causes a severe bleeding disorder.
Oury, Cécile ULg; Toth-Zsamboki, Emese; Van Geet, Chris et al

in Blood (1999)

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See detailCongenital deficiency of the phospholipase C coupled P2Y1 receptor leads to a mild bleeding disorder.
Oury, Cécile ULg; Lenaerts, Tim; Peerlinck, Kathelijn et al

in Thrombosis and Haemostasis (1999)

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See detailSome phase equilibrium constraints on the origin of Proterozoic Massif anorthosites and related rocks
Longhi, John; Vander Auwera, Jacqueline ULg; Fram, Miranda et al

in Journal of Conference Abstracts (1999), 41

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See detailNon-invasive assessment of tumor hypoxia with the 2-nitroimidazole 18F-EF1 and PET.
HUSTINX, Roland ULg; EVANS, SM.; KACHUR, CY. et al

in Journal of Nuclear Medicine (The) (1999), 40

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See detailStable classical configurations in strongly driven helium
Schlagheck, Peter ULg; Buchleitner, A.

in Physica D: Nonlinear Phenomena (1999), 131(1-4), 110-124

We present a detailed analysis of the classical dynamics of the frozen-planet configuration of helium in an external, linearly polarized electromagnetic field. It is shown that the phase space of the ... [more ▼]

We present a detailed analysis of the classical dynamics of the frozen-planet configuration of helium in an external, linearly polarized electromagnetic field. It is shown that the phase space of the collinear frozen planet in the held is mixed regular-chaotic and exhibits regular islands corresponding to nonlinear resonances between the periodic external force and the frozen-planet dynamics. An analysis of the transverse stability properties of the configuration shows that - except for regular regions corresponding to high-order atom-field resonances - the configuration is generally unstable with respect to deviations from collinearity. We find that stability of the driven frozen planet in all phase space dimensions can be enforced by the application of an additional, static electric field. The minimum atomic excitation necessary fur the localization of a quantum state on the thereby stabilized atom-field resonances is estimated. (C) 1999 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailPan-african acidic magmatism in the south Carpathians (Romania): from calc-alkaline to shoshonitic and back
Berza, Tudor; Duchesne, Jean Clair; Vander Auwera, Jacqueline ULg et al

in Documents du BRGM (1999), 290

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See detailPotassic and ultrapotassic dikes around the plutons of Biella and Traversella
Bogaerts, Michel; Vander Auwera, Jacqueline ULg

in Documents du BRGM (1999), 290

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See detailAlcohol-non-preferring Sardinian rats exhibit a higher ethanol-induced taurine increase compared to alcohol-preferring Sardinian rats: a microdialysis study
Quertemont, Etienne ULg; Lallemand, Frédéric; Colombo, Giancarlo et al

in Alcohol & Alcoholism (1999), 34

It is well known that ethanol injections induce increases in the extracellular taurine concentration from various rat brain regions. Furthermore, recent studies have shown that taurine supplementation ... [more ▼]

It is well known that ethanol injections induce increases in the extracellular taurine concentration from various rat brain regions. Furthermore, recent studies have shown that taurine supplementation modulates the ethanol reinforcing effects in a place conditioning experiment. However, it is unknown whether there is a relationship between this taurine increase and the ethanol drinking behaviors. In the present microdialysis experiments, we compared the effects of ethanol injections (1.0 and 2.0 g/kg) on the extracellular taurine concentration from the nucleus accumbens of either Sardinian alcohol-preferring or Sardinian alcohol-non-preferring rats which have been selectively bred for their differential ethanol preference. The results show that acute ethanol produces an immediate increase in the taurine microdialysate content from both rat lines. However, this increase in taurine microdialysate content was more potent in the alcohol-non-preferring rats. Since taurine has been postulated to be released by brain cells to modulate some of the adverse effects of ethanol, the higher increase in taurine microdialysate content in the alcohol-non-preferring rats is probably related to their higher vulnerability to ethanol aversive effects. [less ▲]

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See detailGenetics of lactation persistency
Swalve, H. H.; Gengler, Nicolas ULg

in British Society of Animal Science Occasional Publication (1999), 24

Lactation persistency, often simply called persistency, in general can be defined as the ability to maintain yields during the lactation. Persistency has an impact on feed costs, health, and fertility. Of ... [more ▼]

Lactation persistency, often simply called persistency, in general can be defined as the ability to maintain yields during the lactation. Persistency has an impact on feed costs, health, and fertility. Of these three components affected by persistency, the impact of persistency on health, i.e. metabolic stress of the cow leading to health problems, may be most important nowadays. Numerous suggestions for criteria of persistency exist. Often simple ratios of part-lactation yields, e.g. the ratio of yield in the first and last 100 days of lactation, have been used. New approaches have used results from the application of random regression test day models developed for the genetic evaluation of yield traits. Many studies have unfortunately neglected the effect of gestation on persistency but acknowledged that an improved persistency should lead to an improved reproductive performance. Both relationships should be considered in genetic analyses and recommendations for improvement of management decisions. Today the correct description of persistency plays a prominent role to obtain correct genetic evaluations based on test day yields. But, although apparently trivial, a direct genetic analysis of lactation persistency and even more an inclusion of this trait into selection programmes clearly is a complicated task. A reason for this, amongst others, is that management strategies for feeding during the lactation and handling of the reproductive performance that are most often not recorded, are likely to mask the real persistency. Future studies on the genetics of persistency should also seek a strong interaction of geneticists and physiologists as persistency is fundamentally confounded with the problem of metabolic stress. Today, a recommendation of the inclusion of persistency in selection programmes appears to be premature and more studies, e. g. on the association of persistency with longevity, could aid in this process. [less ▲]

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See detailLack of contribution of two endotelial nitric oxide synthase (eNOS) gene polymorphisms to diabetic nephropathy in type 1 diabetes
Weekers, Laurent ULg; Hadjadj, S.; Belloum, R. et al

in Diabetologia (1999), 42(Sup. 1), 226

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See detailSuspected environmental zinc poisoning in a foal
Amory, Hélène ULg; Christman, U; Gangl, M et al

in Journal of Equine Veterinary Science (1999), 19

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See detailGravity induced tectonics in the Rogaland anorthositic province, Southwest Norway
Bolle, Olivier ULg; Diot, Hervé; Barnichon, Jean-Dominique et al

in Documents du BRGM (1999), 290

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See detailNew 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as putative KATP channel openers: design, synthesis and pharmacological evaluation
Somers, F.; De Tullio, Pascal ULg; Boverie, S. et al

in Fundamental & Clinical Pharmacology (1999), 13

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See detailPharmacological study of original 3-alkylamino-2-methyl-2H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides
Ouedraogo, R.; Nguyen, Q.-A.; Antoine, M.-H. et al

in Fundamental & Clinical Pharmacology (1999), 13

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See detailChanges in the amygdala amino acid microdialysate after conditioning with a cue associated with ethanol
Quertemont, Etienne ULg; de Neuville, Jessica; De Witte, Philippe

in Alcohol & Alcoholism (1999), 34

The excitatory amino acid neurotransmission within the amygdala has been implicated in learning associations between external stimuli and intrinsic reward values such that it may play a key role in ... [more ▼]

The excitatory amino acid neurotransmission within the amygdala has been implicated in learning associations between external stimuli and intrinsic reward values such that it may play a key role in conditioned drug effects. In the present studies, the responses of the excitatory amino acids, aspartate and glutamate together with the neuromodulatory sulphonated amino acid taurine, within the basolateral amygdala, to an odor cue repeatedly associated with acute ethanol injections (2g/kg, IP) have been investigated by a microdialysis technique combined with HPLC-EC analysis. After presentation of the ethanol-conditioned stimulus, a single IP saline injection induced an immediate and significant increase in the taurine microdialysate content which could be related to the neuromodulatory action of taurine. Furthermore, when the conditioned stimulus was combined with the ethanol injection (2g/kg, IP), significant increases in both taurine and glutamate microdialysate content were observed and indicated a learned compensatory response to counteract the acute effects of ethanol. These results demonstrate that changes in amygdala extracellular glutamate and taurine concentrations can be conditioned to ethanol-associated stimuli and are therefore probably implicated in the phenomenon of environmental-dependent tolerance to ethanol. [less ▲]

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See detailRisedronate significantly reduces vertebral and non-vertebral fractures in osteoporotic women
Roux, C; Keller, M; Eastell, R et al

in Journal of Bone and Mineral Research (1999), 14(S1), 538

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See detailIn vivo et in vitro effect of new glibenclamide isosteres
Lebrun, P.; Ouedraogo, R.; Nguyen, Q.-A. et al

in Fundamental & Clinical Pharmacology (1999), 13, Suppl. 1

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See detailRisedronate reduces fracture risk in women with established postmenopausal osteoporosis
Eastell, R; Minne, H; Sorensen, O et al

in Calcified Tissue International (1999), 64(S1), 43

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See detailPharmacological evaluation of 3-alkylsulfanyl-4H-1,2,4-benzothiadiazine 1,1-dioxides structurally related to the KATP channel opener diazoxide
Boverie, S.; Nguyen, Q.-A.; De Tullio, Pascal ULg et al

in Fundamental & Clinical Pharmacology (1999), 13

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See detailVegetative endocarditis in 2 young horses
Amory, Hélène ULg; Christmann, U; Cassart, Dominique ULg et al

in Journal of Equine Veterinary Science (1999), 19

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See detailOesophageal stricture in 5 foals
Christmann, U; Amory, Hélène ULg

in Journal of Equine Veterinary Science (1999), 19

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See detailImpact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: An ROC analysis.
HUSTINX, Roland ULg; DOLIN, RJ.; BENARD, F. et al

in Journal of Nuclear Medicine (The) (1999), 40

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See detailStudy of adsorption effects in the analysis of pharmaceutical formulations by CE
Fotsing, L.; Fillet, Marianne ULg; Chiap, Patrice ULg et al

in Journal de Pharmacie de Belgique (1999), 54

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See detailDynamics of rRNA within the nucleolus: a study by confocal and electron microscopy
Thiry, Marc ULg; O'Donohue, M-F; Kaplan, H et al

in Analytical Cellular Pathology : The Journal of the European Society for Analytical Cellular Pathology (1999), 18

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See detailDetermination of total homocysteine in plasma by automated fluorescence polarization immunoassay
Chapelle, Jean-Paul ULg; Gielen, Jacques; Legrand, Victor ULg et al

in Clinical Chemistry & Laboratory Medicine (1999), 37(suppl), 373

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See detailAn association demonstrated between homocysteine, CRP and troponin levels in PTCA patients
Lutteri, Laurence ULg; Chapelle, Jean-Paul ULg; Gielen, Jacques

in Acta Clinica Belgica. Supplementum (1999), (suppl.1), 15

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See detailExploration de la mémoire prospective dans le vieillissement normal
Bastin, Christine ULg; Meulemans, Thierry ULg

in Revue de Neuropsychologie (1999), 9

Certaines études (par exemple, Einstein et McDaniel, 1990) ont montré que le vieillissement normal affecterait les situations de mémoire prospective « time-based » (où l’action doit être réalisée à un ... [more ▼]

Certaines études (par exemple, Einstein et McDaniel, 1990) ont montré que le vieillissement normal affecterait les situations de mémoire prospective « time-based » (où l’action doit être réalisée à un moment particulier dans le temps), mais pas les situations « event-based» (où la réalisation de l’action est liée à un événement particulier). L’objectif du présent travail était d’explorer les effets du vieillissement normal sur les situations « event-based » et « time-based », en veillant à adapter aux capacités de mémoire de travail de chaque sujet le degré de difficulté de la tâche concurrente (dans laquelle est imbriquée l’action prospective). Les résultats confirment ce qu’ont trouvé Einstein et McDaniel : une absence d’effet de l’âge pour la tâche event-based et des performances inférieures dans la tâche « time-based » pour les sujets âgés. Ces résultats peuvent être interprétés dans le cadre d’une réduction des ressources attentionnelles liée au vieillissement ; nous suggérons par ailleurs qu’un problème spécifique de contrôle du temps pourrait également expliquer l’effet de l’âge sur la tâche time-based. [less ▲]

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See detailLa variation de l’équilibre glycémique (mais pas du poids) est correlée positivement à la modification du risque cardio-vasculaire absolu chez le sujet diabétique
Hadjadj, Samy; Guilloteau, Gérard; Weekers, Laurent ULg et al

in Archives des Maladies du Coeur et des Vaisseaux (1999), 92

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See detailAn improved synthesis of 9-[(3)-[F-18]fluoro-1-hydroxy-2-propoxy)methyl]guanine ([F-18]FHPG).
SHIUE, CY.; SHIUE, GG.; HUSTINX, Roland ULg et al

in Journal of Nuclear Medicine (The) (1999), 40

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See detailSafety of strontium ranelate in prevention of postmenopausal bone loss - a double-blind, prospective, placebo-controlled study
Reginster, Jean-Yves ULg; Roux, C; Jupsin, I et al

in Journal of Bone and Mineral Research (1999), 14(S1), 412

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See detailRisedronate is well-tolerated in women with osteoporosis
McClung, M; Eastell, R; Watts, N et al

in Journal of Bone and Mineral Research (1999), 14(S1), 538

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See detailEffects of nimesulide and indomethacin on cyclooxygenaxse-1 and 2 : a comparative study
De Leval, X; Dogne, JM; Neven, P et al

in Osteoarthritis and Cartilage (1999), 7(SA), 32

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See detailCharacterization of acetification enzymes from thermotolerant acetic acid bacteria, Acetobacter pasteurianus VM 136.
Mouanda, P.; Thonart, Philippe ULg; Tanazefti, H. et al

in Mededelingen Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen Universiteit Gent (1999), 64(5a),

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See detailIn vitro induced imbalance between stromelysin and TIMP-1 production by human chondrocytes
Henrotin, Yves ULg; Labasse, A; Crielaard, Jean-Michel ULg et al

in Osteoarthritis and Cartilage (1999), 7(SA), 33

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See detailp-[18F]MPPF, 5-HT1A antagonist: comparison to [3H]8-OH-DPAT with autoradiography
Plenevaux, Alain ULg; Weissmann, D.; Lemaire, Christian ULg et al

in Society for Neuroscience / Abstracts (1999)

p-MPPF 4-(2’-methoxyphenyl)-1-[2’-[N-(2’’-pyridinyl)-p-fluorobenzamido] ethyl]piperazine is the para-fluorobenzoyl analog of the highly selective 5-HT1A antagonist WAY-100635. The one step procedure used ... [more ▼]

p-MPPF 4-(2’-methoxyphenyl)-1-[2’-[N-(2’’-pyridinyl)-p-fluorobenzamido] ethyl]piperazine is the para-fluorobenzoyl analog of the highly selective 5-HT1A antagonist WAY-100635. The one step procedure used to label p-MPPF with fluorine-18 (cyclotron produced positron emitter of 110 min half-life) leads to a radiopharmaceutical compound easily prepared on a large scale. The preliminary evaluations conducted in rats and cats are good reason to consider p-[18F]MPPF as an interesting reversible radioligand to study the 5-HT1A receptor family in humans with positron emission tomography (PET). In this paper we report a careful comparison between p-[18F]MPPF and [3H]8-OH-DPAT with autoradiography and quantitative densitometry in the same animal. All experiments were conducted in Sprague Dawley male rats. For p-[18F]MMPF, the results were obtained ex-vivo after an intravenous injection of high specific activity radioligand (0.8-1.5 Ci/µmol) in vigil (no anesthesia), free moving and unstressed animals. For the purpose, permanent cannulation of the posterior vena cava were realized at least four days in advance. The [3H]8-OH-DPAT results were obtained in vitro on adjacent coronal sections to the one used for the p-[18F]MPPF autoradiography. Quantitative densitometry was employed to compare the values obtained in relevant brain structures (frontal cortex, lateral septum, hippocampus, dorsal raphe, entorhinal cortex and cerebellum). The plot of the p-[18F]MPPF values obtained for each structure against the [3H]8-OH-DPAT results displayed a significant linear correlation. These results demonstrate that from a qualitative as well as quantitative point of view, the binding of p-[18F]MPPF is totally comparable to the one of [3H]8-OH-DPAT. Supported by grants from INSERM/CGRI and FNRS Belgium. [less ▲]

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See detailDNA and RNA distribution in the nucleus of trypanosomatids: a cytochemical and immunocytochemical study
Motta, M C M; De Souza, W; Thiry, Marc ULg

in Memorias do Instituto Oswaldo Cruz (1999), 94

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See detailRaloxifene therapy for 3 years reduces the risk of incident vertebral fractures in postmenopausal women
Delmas, PD; Ensrud, KE; Harris, S et al

in Calcified Tissue International (1999), 64(S1), 43

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See detailInterest of a simple pre-screening test for optimazing the cost/benefit value of bone densitometry
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in Arthritis and Rheumatism (1999), 42(S1), 289

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See detailIncreasing incidence of equine motor neurone disease in Belgium
Christmann, U; Noppe, E; Cassart, Dominique ULg et al

in Journal of Equine Veterinary Science (1999), 19

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See detailNew hope for CSWS/ESES treatment: Topiramate?
Symann, S.; Rucquoy, M.; Misson, Jean-Paul ULg et al

in European Journal of Paediatric Neurology : Official Journal of the European Paediatric Neurology Society (1999)

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See detailCommunication strategy increases osteoporosis awareness in postmenopausal women
Tellier, V; De Maeseneer, J; Cartier, P et al

in Journal of Bone and Mineral Research (1999), 14(S1), 385

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See detailCharnockites: the lower crust connection
Duchesne, Jean Clair; Vander Auwera, Jacqueline ULg; Bolle, Olivier ULg

in Documents du BRGM (1999), 290

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See detailPinhole SPECT of small animals using vendor standard equipment.
Seret, Alain ULg; Schoutens, André; Blocklet, Didier et al

in Tijdschrift voor Nucleaire Geneeskunde (1999), 21(3), 103-104

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See detailMagmatic intrusion and mineralization along a strike-slip fault into the Åna-Sira anorthosite: the Tellnes case, Rogaland, Norway
Diot, Hervé; Lambert, Jean-Marc; Bolle, Olivier ULg et al

in Documents du BRGM (1999), 290

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See detailMedian root prior for DMSA cortical renal SPET
Seret, Alain ULg; Blocklet, Didier; Schoutens, André

in Tijdschrift voor Nucleaire Geneeskunde (1999), 21(3), 104

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See detailAdverse effects of edema on adjacent gray matter function in patients with brain tumor as determined by FDG-PET imaging.
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in Journal of Nuclear Medicine (The) (1999), 40

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See detailMedian root prior for DMSA cortical renal SPET
Seret, Alain ULg; Blocklet, Didier; Schoutens, André

in European Journal of Nuclear Medicine (1999), 26

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See detailOptimization of a high performance thin layer chromatography method to quantify solanines in patatoes
Bodart, P.; Hubert, Philippe ULg; Angenot, Luc ULg et al

in Journal de Pharmacie de Belgique (1999), 54

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See detailSynthesis and in vivo evaluation of 6-fluoro-a-methyl-L-tryptophan.
Lambin, D.; Tadino, V.; Olynyk, C. et al

in American Chemical Society / Abstracts (1999)

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See detailThymic insulin-related polypeptides in diabetes-prone Bio-Breeding rats
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in Diabetologia (1999), 42 (Suppl. 1)

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See detailThymic neuroendocrine self-antigens. Role in T-cell development and central T-cell self-tolerance
Geenen, Vincent ULg; Kecha, Ouafae

in Neuroimmunomodulation (1999), 6

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See detail5-HT1A receptor distribution in the human brain: preliminary PET data with p-[18F]MPPF.
Fuchs, Sonia ULg; Plenevaux, Alain ULg; Degueldre, Christian ULg et al

in Society for Neuroscience / Abstracts (1999), 25

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See detailRisedronate produces dose-dependent increases in bone mineral density in postmenopausal women with low bone mass
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in Calcified Tissue International (1999), 64(S1), 69

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See detailFactors involved in the bystander effect induced by Varicella zoster and Herpes simplex viral thymidine kinase suicide gene therapy
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in Journal of Gene Medicine (The) (1999), 1

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See detailA Comparative Study of the Antimycotic Activity of a Miconazole Hp-Beta Cyclodextrin Solution and a Surfactant Solution
Piel, Géraldine ULg; Hayette, Marie-Pierre ULg; Evrard, Brigitte ULg et al

in Journal de Pharmacie de Belgique (1999), 54(3, May-Jun), 87-8

The antimycotic activity of a new parenteral solution containing miconazole was compared to that of a marketed solution (Daktarin IV solution). This solution has been withdrawn from the belgian market ... [more ▼]

The antimycotic activity of a new parenteral solution containing miconazole was compared to that of a marketed solution (Daktarin IV solution). This solution has been withdrawn from the belgian market probably because of the toxic effects related to the presence of polyoxyl 35 castor oil. We propose a new formulation containing 10 mg of miconazole per ml (as the marketed solution), in combination with HP-beta cyclodextrin and lactic acid. The MIC of these two solutions were determined by broth microdilution method (following the NCCLS guidelines) against 15 yeasts and 16 filamentous fungi isolates. This study showed that MIC obtained with these two solutions are not significantly different. In vitro, the cyclodextrin solution has the same antimycotic activity as the Daktarin IV solution and can be proposed as a safe and effective parenteral solution to replace the previous surfactant solution. [less ▲]

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