Etude pharmacologique comparative de quelques 3-alkylamino-4H-1,2,4-benzo- et pyridothiadiazine 1,1-dioxydes, activateurs de canaux potassiques ATP-dépendants

in Journal de Pharmacie de Belgique (1998), 53

Conception et synthèses d’activateurs potentiels de canaux potassiques sensibles à l’ATP et bioisostères du BMS 180448

in Journal de Pharmacie de Belgique (1998), 53

3-Alkylamino-7-halogeno-4H-1,2,4-benzothiadiazine 1,1-dioxides as new potent KATP channels activators

in European Journal of Pharmaceutical Sciences (1998), suppl.1

In vitro models for the study of cartilage damage and repair

in Rheumatology in Europe (1998), 27(S2), 7

Tentatives de synthèse énantiosélective des isomères R et S du pirlindole

in Journal de Pharmacie de Belgique (1998), 53

Transmission du virus de l'hépatite C par examens médicaux invasifs

in Gastroentérologie Clinique et Biologique (1998), 22(2), 172

Nucleolus-associated bodies in meristematic cells of Pisum sativum

in Cell Biology International (1998), 22

Which test for which patient ?

in Osteoporosis International (1998), 8(S3), 152

Quantitative analysis of l-lysine n-acetylcysteinate and related compounds by LC-MS

in Journal de Pharmacie de Belgique (1998), 53

Quand Eros a les honneurs du culte

in Uranie : Mythes et Littératures (1998), 8

Liquid chromatographic separation of pirlindole enantiomers using different types of chiral stationary phases

in Journal de Pharmacie de Belgique (1998), 53

Stereoselective determination of s-naproxen in tablets by capillary electrophoresis

in Journal de Pharmacie de Belgique (1998), 53

Assessment of osteoporosis disease burden in countries currently lacking such studies

in BONE (1998), 23(S5), 306

Verifying Systems with Infinite but Regular State Spaces

in Lecture Notes in Computer Science (1998), 1427

Thanks to the development of a number of efficiency enhancing techniques, state-space exploration based verification, and in particular model checking, has been quite successful for finite-state systems ... [more ▼]

Thanks to the development of a number of efficiency enhancing techniques, state-space exploration based verification, and in particular model checking, has been quite successful for finite-state systems. This has prompted efforts to apply a similar approach to systems with infinite state spaces. Doing so amounts to developing algorithms for computing a symbolic representation of the infinite state space, as opposed to requiring the user to characterize the state space by assertions. Of course, in most cases, this can only be done at the cost of forgoing any general guarantee of success. The goal of this paper is to survey a number of results in this area and to show that a surprisingly common characteristic of the systems that can be analyzed with this approach is that their state space can be represented as a regular language. [less ▲]

Method development strategies for the rapid enantioseparation of drugs by capillary electrophoresis using cyclodextrins as chiral additives

in Journal de Pharmacie de Belgique (1998), 53

Preparative resolution of racemic pirlindole: chromatographic methods and determination of the absolute configuration

in European Journal of Pharmaceutical Sciences (1998), suppl.1

What is the role of bone forming agents ?

in Osteoporosis International (1998), 8(S3), 4

Influence des résidus de pesticides sur la Santé de l'Homme

in Acta Clinica Belgica (1998)

Utilisation de Biopesticides sur pommes en post-récolte

in Journées Techniques Nationales de l'Agriculture Biologique (1998)

Neurobiologie Comportementale de l'éthanol et de l'acétaldéhyde

in Alcoologie (1998), 20(4), 391-391

Effects of regular or lispro insulin on glucose metabolism after an oral glucose load in patients with type 2 diabetes mellitus

in Diabetes (1998), 47(suppl 1), 3

Vers un Observatoire de la Faune, de la Flore et des Habitats.

in Travaux de la Conservation de la Nature (1998), 20

Effets de l’administration d’une insuline ordinaire (regular) et d’un analogue de l’insuline (lispro) sur le métabolisme postprandial du glucose chez le sujet diabétique de type 2

in Diabète & Métabolisme (1998), 24(suppl 1), 3

A survey on the safe and effective use of pesticides in cut flower production: the case of highlands of northern Thailand.

in Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen (Rijksuniversiteit te Gent) (1998), 63(2a),

Electronic contribution to the thermal diffusivity: DyBa2Cu3O7-y and Y0.9Ca0.1Ba2Cu3O7-z

in International Journal of Modern Physics B : Condensed Matter Physics, Statistical Physics, Applied Physics (1998), 12(29-31), 3087-3090

The electronic contribution to the specific heat and the thermal conductivity of high-T-c superconductors is calculated with a three-dimensional band structure including saddle points and a Lawrence ... [more ▼]

The electronic contribution to the specific heat and the thermal conductivity of high-T-c superconductors is calculated with a three-dimensional band structure including saddle points and a Lawrence-Doniach coupling between the CuO2 planes. The electronic thermal diffusivity is deduced for s- and d-wave symmetry of the order parameter. Data on DyBa2Cu3O7-y and Y0.9Ca0.1Ba2Cu3O7-z and theory are in good agreement on the change of the slope near T-c. [less ▲]

Ab initio phonon dispersion curves and interatomic force constants of barium titanate

in Ferroelectrics (1998), 206(1-4), 205-217

The phonon dispersion curves of cubic BaTiO3 have been computed within a first-principles approach and the results compared to the experimental data. The curves obtained are very similar to those reported ... [more ▼]

The phonon dispersion curves of cubic BaTiO3 have been computed within a first-principles approach and the results compared to the experimental data. The curves obtained are very similar to those reported for KNbO3 by Yu and Krakauer (Phys. Rev. Lett., 74, 4067 (1995)). They reveal that correlated atomic displacements along [100] chains are at the origin of the ferroelectric instability. A simplified model illustrates that spontaneous collective displacements will occur when a dozen of aligned atoms are coupled. The longitudinal interatomic force constant between nearest neighbour Ti and O atoms is relatively weak in comparison to that between Ti atoms in adjacent cells. The small coupling between Ti and O displacements seems however necessary to reproduce a linear ferroelectric instability. [less ▲]

Regulation of the chondrocyte metabolism by a new divalent strontium salt (S12911)

in BONE (1998), 23(S5), 344

The effect of 2 and 3 years of Raloxifene on vertebral and non-vertebral fractures in postmenopausal women with osteoporosis

in BONE (1998), 23(S5), 174

On-line coupling of dialysis to liquid chromatography for the automated determination of some local anaesthetics in human plasma

in Journal de Pharmacie de Belgique (1998), 53

radiosensitizers FMdC and idUrd: HPLC-analysis in vitro

in Radiotherapy & Oncology (1998), 48(Supp 1),

Effets du monoxyde d’azote (NO) sur le métabolisme des chondrocytes

in Revue du Rhumatisme (1998), 11

Validation of an automated method for the LC determination of atenolol in plasma : application of a new validation strategy

in Journal de Pharmacie de Belgique (1998), 53

Nitric oxid (NO) down-regulates cytokines and PGE2 production by human chondrocytes

in Revue du Rhumatisme (English ed.) (1998), 11

(E)-2'-Deoxy-2'-(Fluoromethylene)cytidine potentiates radioresponse of two human solid tumor xenografts.

in Proceedings of the American Association for Cancer Research (1998)

Antitumor and radiosensitizing effects of (E)-2'-deoxy-2'-(fluoromethylene) cytidine (FMdC), a novel inhibitor of ribonucleotide reducÃase, were evaluated on nude mice bearing s.c. human C33-A cervix ... [more ▼]

Antitumor and radiosensitizing effects of (E)-2'-deoxy-2'-(fluoromethylene) cytidine (FMdC), a novel inhibitor of ribonucleotide reducÃase, were evaluated on nude mice bearing s.c. human C33-A cervix cancer and I -H7 MG glioblastoma xenografts. FMdC given once daily has a dosedependent antitumor effect. The maximum tolerated dose in the mice was reached with 10 daily i.p. administrations of 10 mg/kg over 12 days. In the case of radiotherapy (RT) alone (10 fractions over 12 days), the radiation dose required to produce local tumor control in 50% of the treated C33-A xenografts was 51.0 Gy. When combined with FMdC, the radiation dose required to produce local tumor control was reduced to 41.4 and 38.2 Gy, at respective doses of 5 and 10 mg/kg given i.p. l h before each irradiation. The corresponding enhancement ratios (ERs) were 1.2 and 1.3, respec tively. In U-87 MG xenografts, when 5-20 mg/kg FMdC combined with 30 or 40 Gy of RT, the combination treatment produced a significantly increased growth delay as compared with RT alone (P £0.002). The ERs of 5, 10, and 20 mg/kg FMdC at a dose of 30 Gy were 2.0, 1.4, and 1.8, respectively. At the 40-Gy level, ERs of 10 and 20 mg/kg FMdC were 1.4 and 1.7. When FMdC was combined with 50 Gy of RT, an increased long-term remission rate of 80-88.9% was observed, as compared with 25% for RT alone (P <0.05). FMdC produced moderate myelosuppression in the mice bearing cervix cancer, whereas leukocytosis occurred in the mice bearing glioblastoma at a low dose. Slightly increased skin toxicity (only with U-87 MG tumor) was observed, as compared with RT alone. In conclusion, FMdC is a potent cytotoxic agent and able to modify the radiation response of C33-A and U-87 MG xenografts. [less ▲]

Rural development in Wallonia (Belgium) - Academic point of view.

in Sbornik praci z mezinarodni vedecke konference, Agrarni perspektivyVII. Evropska integrace a vyuzivani prirodnich zdroju, Dil I, Praha,Czech Republic, 17.-18. Zari 1998. (1998)

More and more, european universities will be involved in research topics concerning rural development. Common Agricultural Policy is modified and concerns specific area when the support of european funds ... [more ▼]

More and more, european universities will be involved in research topics concerning rural development. Common Agricultural Policy is modified and concerns specific area when the support of european funds will be focus. In Wallonia, we have a large experience of this kind of policy started in 1981 with Integrated Development Program. The main goal of this paper is to present some characteristics of Wallonia and some research topics initiated by Universities. [less ▲]

Biological treatment of waste gypsum

in Biodegradation (1998)

The presentation presents the investigations about gypsum treatment by sulfate-reducing bacteria

Hybrid wheat - a different wheat crop?

in Aspects of Applied Biology (1997, December 15), (50), 23-30

From 1994 to 1996, trials have been carried out in Gembloux (Belgium) to evaluate the agronomical value of hybrid wheat varieties and to determine the best adapted growing conditions for these new wheats ... [more ▼]

From 1994 to 1996, trials have been carried out in Gembloux (Belgium) to evaluate the agronomical value of hybrid wheat varieties and to determine the best adapted growing conditions for these new wheats. These experiments show that the best hybrids have a yield potential hyghly superior to classical varieties. In order to improve the cost-effectiveness of hybrid wheat crops, a reduction in seed rate may be possible together with changes in nitrogen fertilisation, if the results of preliminary studies are confirmed. [less ▲]

Deformation localisation in continental lithosphere

in EOS (American Geosciences Union abstract) (1997, December), 78

Isokinetic testing of knee musculature in patient with unilateral gonarthrosis

in Revue du Rhumatisme (English ed.) (1997, November), 11

Difunctional initiator based on 1,3-diisopropenylbenzene. 7. Mechanical and thermal properties of new butadiene-based thermoplastic elastomers

in Rubber Chemistry and Technology (1997, November), 70(5), 820-838

Mechanical and thermal properties of SBS thermoplastic elastomers, in which S stands for polystyrene and B for polybutadiene, can be remarkably improved through end-capping by syndiotactic poly(methyl ... [more ▼]

Mechanical and thermal properties of SBS thermoplastic elastomers, in which S stands for polystyrene and B for polybutadiene, can be remarkably improved through end-capping by syndiotactic poly(methyl methacrylate) sequences. Furthermore, the upper service temperature of these sPMMA teleblock copolymers can also be enhanced by blending with isotactic PMMA so that the rubbery PBD soft segments are connected to high-melting stereocomplexed hard segments. The factors which affect the mechanical and thermal properties of these novel thermoplastic elastomers have been extensively investigated. [less ▲]

Epreuves isocinétiques de résistance à la fatigue musculaire

in Annales de Réadaptation et de Médecine Physique (1997, October), 40(6), 469

On the Production and Kinematics of Sodium Atoms in the Head of Comet Hale-Bopp

in Bulletin of the American Astronomical Society (1997, July 01), 29

The interpretation of the presence and extent of the atomic sodium observed in comet Hale-Bopp raises a number of questions related to the production, motion, and lifetime of these Na atoms under the ... [more ▼]

The interpretation of the presence and extent of the atomic sodium observed in comet Hale-Bopp raises a number of questions related to the production, motion, and lifetime of these Na atoms under the action of the solar radiation near 1 AU. Here we report on data which pertain to the study of sodium in the head of the comet, yielding information on the Na emission in the coma out to ~ 0.15 x 10(6) km on the sunward side, to ~ 0.2 x 10(6) km tailwards. The observations were carried out at the Observatoire de Haute-Provence, with the 1.93 m telescope and the ELODIE spectrometer, which is fed by a pair of optical fibers with 2-arcsec apertures separated by 1.8 arcmin. In particular, spectra were obtained on 15-17 April, 1997, near the discovery date of the sodium tail at the La Palma Observatory. These spectra (resolution ~ 7 km/s) were used to determine Na D line profiles, as well as the relative intensities of the emissions corresponding to the two positions observed simultaneously. The main outcome of our first analysis concerns the profiles recorded some distance away from the optical centre, which all show velocity shifts and asymmetric line broadening in the direction of anti-sunward velocities. Some evidence is found to suggest the existence of an extended or multi-source production of sodium atoms, at least in the coma. Another series of spectra secured just before perihelion, 25-27 March, was analysed in the same way as the April spectra. Comparison between the two sets of data provides a nice illustration of the marked influence of the heliocentric radial velocity, not only upon the strength of the fluorescence ("Swings effect"), but also upon the motion of the emitting atoms, which are accelerated by the radiation pressure to widely different degrees as their excitation wavelengths fall at different places within the Fraunhofer Na D line profiles. [less ▲]

Obesity and nutrition. The Belgian Luxembourg Child Study

in International Journal of Obesity (1997, June)

Intérêt et positionnement d'un traitement fongicide avant le stade épiaison sur froment d'hiver dans les conditions culturales de la Belgique

in Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen (Rijksuniversiteit te Gent) (1997, May 06), 62(3b), 1109-1115

Sur des cultures recevant une protection fongicide à large spectre à l'épiaison (GS 59), les effets d'un traitement fongicide effectué soit au stade 31-32 soit au stade 39 ont été examinés au cours des ... [more ▼]

Sur des cultures recevant une protection fongicide à large spectre à l'épiaison (GS 59), les effets d'un traitement fongicide effectué soit au stade 31-32 soit au stade 39 ont été examinés au cours des cinq dernières années. Ces traitements précoces ne se sont avérés rentables que lorsque la pression des maladies était importante. Dans ce cas, les résultats montrent que, généralement, il est préférable d'attendre le stade dernière feuille GS39 pour intervenir. Le risque de perte de rendement par rapport à une intervention au stade GS31-32 est minime; de plus, la décision de traiter et le choix des fongicides sont beaucoup plus aisés. [less ▲]

Etude longitudinale des relations entre la structure financière, la stratégie d'investissement, l e taux de valeur ajoutée et la santé économique des Petites et Moyennes Entreprises belges à caractère industriel

in Cahier de Recherche du Crédit Professionnel / Beroepskrediet (1997, May), 1997(Mai), 1-81

This Working Paper summarizes the main findings emerging from the larger study financed by Crédit Professionnel / Beroepskrediet in the context of the "Chair SME 1995" and dedicated to a global and in ... [more ▼]

This Working Paper summarizes the main findings emerging from the larger study financed by Crédit Professionnel / Beroepskrediet in the context of the "Chair SME 1995" and dedicated to a global and in-depth analysis of the links between financial structure, added value, investment strategy and economic health in industrial Belgian SMEs (9 different industries). [less ▲]

New constraints on the slip rate of the North Anatolian Fault, Turkey

in Terra nova (European Union of Geosciences abstracts) (1997, March), 9

Electrochemical synthesis of new electroactive polymers from dithienylene-vinylene derivatives

in Synthetic Metals (1997, January), 84(1-3), 163-164

Highly conjugated thiophene derivatives, based on thienylene-vinylene and thieneylene-vinylene-phenylene units, have been synthesized in order to examine: (i) the effect of such regular conjugated monomer ... [more ▼]

Highly conjugated thiophene derivatives, based on thienylene-vinylene and thieneylene-vinylene-phenylene units, have been synthesized in order to examine: (i) the effect of such regular conjugated monomer structures on the polymerization; (ii) the optical and electrochemical properties of the corresponding conjugated polymers. The all-trans monomers have been prepared by a Wittig reaction and the polymers have then been synthesized electrochemically. The polymers are electrochromic and can be reversibly doped both oxidatively and reductively. Their electrochemical behavior and optical properties have been analysed on the basis of quantum-chemical calculations. [less ▲]

L'acétylcholinestérase dans le système olfactif de la carpe Cyprinus carpio L. (Poisson, Cyprinidae): utilisation comme biomarqueurs d'exposition à l'égard des insecticides dans le milieu aquatique.

in Annales ANPP (1997), 1

Sea air land modelling operational network

in Lecture Notes in Computer Science (1997), 1225

The purpose of the SALMON project is to develop a single model from three previously existing models (ocean, river and groundwater) for the description of environment quality in a whole system of regional ... [more ▼]

The purpose of the SALMON project is to develop a single model from three previously existing models (ocean, river and groundwater) for the description of environment quality in a whole system of regional scale including marine, river, groundwater and atmospheric inputs. The connection of the different models is done through a specific interface, a junction, designed to allow the data exchange between models based on different numerical methods. The software is developed on IBM RS/6000 computers (the SP2 parallel machine). [less ▲]

Numerical modelling of the Canary Upwelling

in Annales Geophysicae. Series B, Terrestrial and Planetary Physics (1997), 15(suppl. II),