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See detailMeasurement of progesterone concentration in plasma samples: comparison of three radioimmunoassay procedures
Legras, B.; Beckers, Jean-François ULg; Sulon, J.

in Reproduction (Cambridge, England). Abstract Series (2004), 31

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See detailGain baro-réflexe calculé lors d’un test d’orthostatisme (« squatting ») : reproductibilité et effet de l’âge dans une population normale
PHILIPS, Jean-Christophe ULg; MARCHAND, Monique ULg; Estrella, F. et al

in Archives des Maladies du Coeur et des Vaisseaux (2004), 97(suppl), 5392

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See detailInfluence of blood glucose control on the progression of cardiac autonomic neuropathy in Type 1 diabetes.
PHILIPS, Jean-Christophe ULg; MARCHAND, Monique ULg; Geronooz, I. et al

in Diabetologia (2004), 47(suppl 1), 368-3691029

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See detailSimenon et la “crise” du roman
Denis, Benoît ULg

in Traces. Travaux du Centre d'Études Georges Simenon (2004), (15), 95-106

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See detailEffects of cromakalim analogues on rat pancreatic B-cells, rat aorta rings and rat uterus. Study of their mechanism of action as potassium channel activators
Sebille, S.; Boverie, S.; Becker, B. et al

in Fundamental & Clinical Pharmacology (2004)

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See detailEffect of ADAMTS-2, a metalloproteinase containing a disintegrin domain and thrombospondin type I repeats, during angiogenesis in vitro and in vivo
Dubail, Johanne ULg; Kesteloot, Frédéric ULg; Motte, Patrick ULg et al

in Angiogenesis (2004), 7(2), 172

Formation of new blood vessels (angiogenesis) is a key step during the development of various pathologies, including cancer. Enzymes of the ADAMTS family are closely related to MMPs and ADAMs. They ... [more ▼]

Formation of new blood vessels (angiogenesis) is a key step during the development of various pathologies, including cancer. Enzymes of the ADAMTS family are closely related to MMPs and ADAMs. They further contain specific domains, such as the ‘‘Thrombospondin type I’’ (TSP1) repeats, that are able to strongly repress angiogenesis, as described for thrombospondin-1 and -2, and for ADAMTS-1 and -8. The primary function of ADAMTS-2 is to process collagen type I, II and III precursors into mature molecules by excising the aminopropeptide. We further hypothesized that it could modulate angiogenesis through its TSP1 repeats. This hypothesis was investigated using different in vitro experimental models of angiogenesis. Recombinant ADAMTS-2 induced morphological changes in human umbilical vein endothelial cells (HUVEC) and human microvessel endothelial cells (HMEC), and significantly reduced their proliferation, attachment and spreading. Similar effects were observed when using inactive ADAMTS-2 mutated at the Zn2+-binding catalytic site. ADAMTS-2 did not alter the initial steps of formation of capillary-like structures by HUVEC in vitro. However, these structures appeared much less stable and were more rapidly disrupted in presence of ADAMTS-2 than in control conditions. ADAMTS-2 was also tested in an ex vivo angiogenesis model using aortic rings from rats and mice, wild type or KO for ADAMTS-2. Outgrowth of capillaries was slightly increased from aortas of ADAMTS-2 KO mice (TS2-/-) as compared to aortas from control animals (TS2+/+), while addition of full size recombinant ADAMTS-2 reduced the formation of capillary structures from rat aortas, suggesting its anti-angiogenic activity. Choroidal neovascularization induced in TS2+/+ or TS2-/- mice by LASER burns was used as in vivo model to confirm the in vitro and ex vivo results. Several genes involved in the healing and angiogenesis processes (fibrillar collagens, VEGF, TGF-beta and CTGF) were not differently regulated in TS2+/+ and TS2-/- mice at 5 days. [less ▲]

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See detailExcitabilité nerveuse et neuropathies périphériques : résultats d’une étude multicentrique
Kuntzer, Thierry; Carrera, E; Boërio, D et al

in Neurophysiologie Clinique = Clinical Neurophysiology (2004)

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See detailNew analogues of the KATP channel opener cromakalim : synthesis and pharmacological evaluation on rat pancreatic B-cells and rat aorta rings
Sebille, S.; De Tullio, Pascal ULg; Antoine, M. H. et al

in Fundamental & Clinical Pharmacology (2004)

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See detailCharacterization of preferential activity on platelet thromboxane A2 receptors of BM-613, a new thromboxane A2 antagonist
Hanson, Julien ULg; Rolin, S.; De Leval, X. et al

in Fundamental & Clinical Pharmacology (2004)

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See detailInvestigation on prenatal endocrinology: preliminary results on long term catheterisation of bovine foetuses
Touati, Kamal ULg; Melo de Sousa, Noelita ULg; Gangl, M. et al

in Reproduction (Cambridge, England). Abstract Series (2004), 31

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See detailLiving related liver transplantation in adults: First year experience at the University of Liege
DETRY, Olivier ULg; DE ROOVER, Arnaud ULg; DELWAIDE, Jean ULg et al

in Acta Gastro-Enterologica Belgica (2004), 67

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See detailHCV genotype 5: an easy to treat population
REENAERS, Catherine ULg; DELWAIDE, Jean ULg; GERARD, Christiane ULg et al

in Acta Gastro-Enterologica Belgica (2004), 67

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See detailLaparoscopic sigmoidectomy for fistulized diverticulitis
Laurent, S; DETROZ, Bernard ULg; DETRY, Olivier ULg et al

in Acta Gastro-Enterologica Belgica (2004), 67

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See detailLuminal contact improves human small bowel preservation
DE ROOVER, Arnaud ULg; de Leval, Laurence ULg; GILMAIRE, Julie ULg et al

in Acta Gastro-Enterologica Belgica (2004), 67

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See detailRadioimmunoassay of bovine placental lactogen (bPL) using an antiserum raised in guinea pigs: measurement in foetal plasma
Alvarez-Oxiley, A. V.; Melo de Sousa, Noelita ULg; Touati, Kamal ULg et al

in Reproduction (Cambridge, England). Abstract Series (2004), 31

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See detailEarly release of myeloperoxydase and lactoferin after direct stenting in patient presented for unstable angina
Gach, Olivier ULg; Biemar, C.; Pierard, Luc ULg et al

in European Heart Journal (2004), 25(Suppl. S), 450-450

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See detailHpatitis C infection: eligibility for antiviral therapies
El souda, R; DELWAIDE, Jean ULg; GERARD, Christiane ULg et al

in Acta Gastro-Enterologica Belgica (2004), 67

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See detailStructure of liquid Te-based alloys used in rewritable DVDs
Delheusy, M.; Raty, Jean-Yves ULg; Detemple, R. et al

in Physica B: Condensed Matter (2004), 350(1-3 SUPPL. 1), 1055-1057

We analyze the structure of Te-based chalcogenide compounds that are used as materials for rewritable DVDs by using a combination of neutron diffraction and ab initio computer simulation. We show that in ... [more ▼]

We analyze the structure of Te-based chalcogenide compounds that are used as materials for rewritable DVDs by using a combination of neutron diffraction and ab initio computer simulation. We show that in the liquid, the atoms have a low average coordination number, as the result of a Peierls distortion. The partial pair correlation functions are obtained from the computer simulation data. © 2004 Published by Elsevier B.V. [less ▲]

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See detailFuranic avocado/soybean unsaponifiables prevent osteoarthritic subchondral osteoblasts-induced cartilage degradation
Sanchez, Christelle ULg; Deberg, Michelle ULg; Piccardi, Nathalie et al

in Osteoarthritis and Cartilage (2004), 12(Suppl. B), 108-109

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See detailSet-up of a camera quality programme in six departments: the initial experience
Seret, Alain ULg

in European Journal of Nuclear Medicine and Molecular Imaging (2004), 31

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See detailImage des dieux et rituel dans le discours de Pausanias : de l’« axiologie » à la théologie
Pirenne-Delforge, Vinciane ULg

in Mélanges de l'École Française de Rome. Antiquité (2004), 116

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See detailInteractions at large distances and spin effects in nucleon-nucleon and nucleon-nuclei scattering
Cudell, Jean-René ULg; Predazzi, E.; Selyugin, Oleg Viktorovich

in Physics of Particles and Nuclei (2004), 35(Suppl. 1), 75-78

The momentum transfer dependence of the slopes of the spin-non-flip and spin-flip amplitudes is analyzed. It is shown that the long tail of the hadronic potential in impact parameter space leads, for ... [more ▼]

The momentum transfer dependence of the slopes of the spin-non-flip and spin-flip amplitudes is analyzed. It is shown that the long tail of the hadronic potential in impact parameter space leads, for hadron-hadron interactions, to a larger value of the slope for the reduced spin-flip amplitude than for the spin-non-flip amplitude. It is also shown that the preliminary measurement of A(N) obtained by the E950 Collaboration confirms such behavior of the hadron spin-flip amplitude. [less ▲]

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See detailGypsum and bassanite in the bat guano deposit from the « dry » Cioclovina cave (Sureanu Mountains, Romania)
Dumitras, Delia; Hatert, Frédéric ULg; Bilai, E. et al

in Romanian Journal of Mineral Deposits (2004), 81

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See detailPhase stability of Triphylite, LiFePO4, and the Phases of the Mason-Quensel-Sequence
Schmid-Beurmann, Peter ULg; Moavenian, M.; Hatert, Frédéric ULg

in Berichte der Deutschen Mineralogischen Gesellschaft : Beihefte zum European Journal of Mineralogy (2004), 16

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See detailTissue distribution and metabolism of D-p-[18F]MPPF in rats.
Defraiteur, C.; Muroni, S.; Lemaire, Christian ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (2004), 45(S2), 444

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See detailUse of pregnancy specific proteins, P4, PGFM and E1S assays to monitor pregnancy in sheep
Gajewski, Z.; Beckers, Jean-François ULg; Melo de Sousa, Noelita ULg et al

in Reproduction in Domestic Animals (2004), 39(4), 288

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See detailStrontium ranelate reduces the risk of vertebral fractures in postmenopausal women with osteopenia
Sawicki, A; Reginster, Jean-Yves ULg; Roux, C et al

in Osteoporosis International (2004), 15(S1), 119-120

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See detailSubchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes
Sanchez, Christelle ULg; Deberg, Michelle ULg; Piccardi, Nathalie et al

in Osteoarthritis and Cartilage (2004), 12(Suppl. B), 99-100

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See detailFebrile convulsions: an update
Lagae, L.; Ceulemans, B.; Misson, Jean-Paul ULg

in Acta Neurologica Belgica (2004)

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See detailStrontium ranelate reduces the risk of vertebral and non-vertebral fractures in Caucasian women with post-menopausal osteoporosis.
Adami, S; Meunier, J; Devogelaer, JP et al

in Calcified Tissue International (2004), 74(S1), 37-38

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See detailGossypol. A substance likely involved in the cotton / Fusarium oxysporum f. sp. vasinfectum interaction
Turco, E; Brubaker, C; Scown, J et al

in Journal of Plant Pathology [=JPP] (2004)

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See detailLocalizable effective theories, bootstrap and the parameters of hadron resonances
Semenov-Tyan-Shanskiy, Kirill ULg; Vereshagin, Alexander; Vereshagin, Vladimir

in AIP Conference Proceedings (2004), 717

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See detailDietary supplementation with chondroitin sulfate and glucosamine HCL does not slow down articular cartilage erosion in biglycan/fibromodulin deficient mice
Henrotin, Yves ULg; Deberg, M; Oliviera, M et al

in Osteoarthritis and Cartilage (2004), 12(Suppl B), 33

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See detailHCV genotype 4 in Belgium: epidemiological characteristics
REENAERS, Catherine ULg; DELWAIDE, Jean ULg; GERARD, Christiane ULg et al

in Acta Gastro-Enterologica Belgica (2004), (67), 03

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See detailRemoval of C-terminal Src kinase from the immune synapse by a new binding protein
Mustelin, Tomas; Rahmouni, Souad ULg; Alonso, Andres et al

in Cancer Research (2004), 45

The Csk tyrosine kinase negatively regulates the Src family kinases Lck and Fyn in T cells. Engagement of the T cell antigen receptor results in a removal of Csk from the lipid raft-associated ... [more ▼]

The Csk tyrosine kinase negatively regulates the Src family kinases Lck and Fyn in T cells. Engagement of the T cell antigen receptor results in a removal of Csk from the lipid raft-associated transmembrane protein PAG/Cbp. Instead, Csk becomes associated with a ∼72-kDa tyrosine phosphorylated protein, which we here identify as G3BP, a phosphoprotein reported to bind the SH3 domain of Ras GTPase activating protein. G3BP reduced the ability of Csk to phosphorylate Lck at Y505 by decreasing the amount of Csk in lipid rafts. As a consequence, G3BP augmented T cell activation as measured by IL-2 gene activation. Conversely, elimination of endogenous G3BP by RNA interference reduced TCR signaling. In antigen-specific T cells, endogenous G3BP moved into a intracellular location adjacent to the immune synapse, but well inside the cell, upon antigen recognition. Csk co-localization with G3BP occurred in this ‘parasynaptic’ location. We conclude that G3BP is a new player in TCR signaling that acts to reduce the amount of Csk in the immune synapse. [less ▲]

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See detailNew possibilities for the diagnosis of early pregnancy (EP) and late embryonic mortality (LEM) in the cow
Szenci, O.; Taverne, M. A. M.; Beckers, Jean-François ULg

in Reproduction in Domestic Animals (2004), 39(4), 252

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See detailGeochemical and Pb isotopic investigations in peat bogs from Southern Chile: Identification of particles supplies and possible paleoclimate record
De Vleeschouwer, François ULg; Ibanez, M.; Mattielli, N. et al

in Geochimica et Cosmochimica Acta (2004), 68(11), 478-478

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See detailUse of heterologous and homologous radioimmunoassay (RIA) for ovine pregnancy-associated glycoprotein (ovPAG) determination to detect pregnancy in sheep
Vandaele, L.; Verberckmoes, S.; De Cat, S. et al

in Reproduction (Cambridge, England). Abstract Series (2004), 31

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See detailOvine pregnancy-associated glycoprotein profiles in ewes pregnant with singletons or twins
Vandaele, L.; Verberckmoes, S.; Van Soom, A. et al

in Reproduction in Domestic Animals (2004), 39(4), 278

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See detailDevelopment of RT-PCR assays using fluorogenic-3 minor groove binder DNA probes for detection of fruit tree viruses.
Roussel, S.; Kummert, J.; Dutrecq, O. et al

in Acta Horticulturae (2004), 657(1),

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See detailApplication of the CALUX bioassay for epidemiological study: analyses of Belgian human plasma
Van Wouwe, Nathalie; Debacker, Noemi; Sasse, André et al

in Organohalogen Compounds (2004)

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See detailProteomic and genomic analysis of Chlamydomonas reinhardtii complex 1: conserved components in eukaryotes
Cardol, Pierre ULg; Vanrobaeys, F.; Devreese, B. et al

in Biochimica et Biophysica Acta-Bioenergetics (2004), 1657(Suppl. 1), 41-42

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See detailComparison of the rat and mouse cell lines commercially available for CALUX bioassays
Goeyens, Leo; Windal, Isabelle; Scippo, Marie-Louise ULg et al

in Organohalogen compounds (2004), 66

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See detailEvaluation of the function of ADAMTS-2, a metalloproteinase containing a disintegrin domain and thrombospondin type I repeats, during angiogenesis in vitro and in vivo
Kesteloot, Frédéric ULg; Lapière, Charles M; Colige, Alain ULg et al

in Acta Clinica Belgica (2004), 59(2), 120

Angiogenesis is required for development, growth, tissue remodeling, and wound healing. Pathologies such as diabetic retinopathy, rheumatoid arthritis and cancer would benefit from therapies controlling ... [more ▼]

Angiogenesis is required for development, growth, tissue remodeling, and wound healing. Pathologies such as diabetic retinopathy, rheumatoid arthritis and cancer would benefit from therapies controlling and reducing angiogenesis. Enzymes of the ADAMTS family are closely related to MMPs and ADAMs. They contain however some specific features, such as a variable number of domains known as “ThromboSpondin type I repeat” (TSPI). ADAMTS-1 and -8 are 20-fold more anti-angiogenic than angiostatin and endostatin, two potent inhibitors of angiogenesis. The primary function of ADAMTS-2 is the maturation of collagen type I and II molecules by excising the amino-propeptide. In addition, ADAMTS-2 could also modulate angiogenesis, as it contains the same sequences than those responsible for the anti-angiogenic activity of ADAMTS-1 and -8. This hypothesis was investigated in vitro in different experimental models such as cell proliferation and formation of capillary structures by human endothelial cells. An ex vivo angiogenesis model was also used. It consists in mice or rat aorta pieces embedded in a collagen gel in order to allow the growth of capillaries from the vascular endothelium. As compared to control mice (TS2+/+), angiogenesis was slightly increased, in absence of ADAMTS-2, from aortas of ADAMTS-2 KO mice (TS2-/-). Using rat aortas, addition of recombinant ADAMTS-2 reduced the formation of capillary structure, also confirming the anti-angiogenic activity of ADAMTS-2. Finally, an in vivo model of angiogenesis was also used. Biocompatible sponges (Ivalon) were implanted under the skin of TS2+/+ or TS2-/- mice in order to evaluate the formation of capillaries in the granulation tissue invading the sponge. In absence of ADAMTS-2, angiogenesis and granulation tissue formation were both reduced. Additional investigations are being performed in order to identify the underlying mechanism(s) inducing these modifications. [less ▲]

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See detailResidual cerebral functioning in the vegetative state
Laureys, Steven ULg; Faymonville, Marie-Elisabeth ULg; De Tiège, X. et al

in Arco di Giano (2004)

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See detailDIOXIN BODY BURDEN AMONG BLOOD DONORS BEFORE AND AFTER THE BELGIAN DIOXIN/PCB INCIDENT
Debacker, Noemi; Sasse, André; Van Wouwe, Nathalie et al

in Organohalogen Compounds (2004)

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See detailRégulation du Métabolisme des Chondrocytes par l'Oncostatine M et l'Interleukine 6
Sanchez, Christelle ULg; Deberg, Michelle ULg; Devel, Philippe et al

in Revue du Rhumatisme (2004), 71(10-11), 1008

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See detailBiochemical findings associated with atypical myopathy in grazing horses
Votion, Dominique ULg; Delguste, Catherine ULg; Amory, Hélène ULg et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailChemo-mechanical interactions in clay: a correlation between clay mineralogy and Atterberg limits
Schmitz, R. M.; Schroeder, Christian ULg; Charlier, Robert ULg

in Applied Clay Science (2004), 26(1-4), 351-358

Among some few others tests, the evaluation of the Atterberg limits is a very basic soil mechanical test allowing a first insight into the chemical reactivity of clays. Basically, the liquid limit and the ... [more ▼]

Among some few others tests, the evaluation of the Atterberg limits is a very basic soil mechanical test allowing a first insight into the chemical reactivity of clays. Basically, the liquid limit and the plasticity index are highly and mainly influenced by the ability of clay minerals to interact with liquids. In this contribution, a correlation between the Atterberg limits and clay mineralogy is proposed. This correlation increases the understanding between clay mineralogists and engineers in soil mechanics; additionally a wealth of information in clay mineralogy literature is now available to predict the mechanical behaviour of clays via index tests. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailPP1 targeting and regulation as revealed by the structure of a PP1 delta-MYPT1 complex.
Terrak, Mohammed ULg; Kerff, Frédéric ULg; Langsetmo, K. et al

in Biophysical Journal (2004), 86(1), 172-172

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See detailConvergence and conditionning issues with X-FEM in fracture mechanics
Béchet, Eric ULg; Minnebo, Hans; Moës, Nicolas

in Computational Mechanics (2004)

Numerical crack propagation schemes were augmented in an elegant manner by the X-FEM method applied to fracture mechanics. The use of special tip enrichment functions, as well as a discontinuous function ... [more ▼]

Numerical crack propagation schemes were augmented in an elegant manner by the X-FEM method applied to fracture mechanics. The use of special tip enrichment functions, as well as a discontinuous function along the sides of the crack allows one to do a complete crack analysis virtually without modifying the underlying mesh, which is of an evident industrial interest. The conventional approach for crack tip enrichment (described in [2,3]) is that only a specific layer of elements are enriched around the crack tip. We show that this “topological” approach does not yield an increase of the order of the asymptotic convergence rate when compared to unenriched finite elements, as when the crack is part of the mesh. It rather modifies the proportionality factor of the asymptotic convergence rate. In this study, we propose another enrichment scheme which yields a convergence rate that appears to be close to that of regular finite elements used when the solution field does not show singularities. The enriched basis in X-FEM degrades the rigidity and mass matrices condition numbers (the mass matrix typically appears in case of time dependent problems such as wave propagation in cracked bodies). To recover the condition number of non enriched matrices, we introduce a preconditioning strategy which acts block-wise on the set of enriched degrees of freedom associated to each node. This strategy uses a local (nodal) Cholesky based decomposition. Another issue is brought by the integration scheme used to build the matrices. The nature of the asymptotic functions are such that any Gauss-Legendre based integration scheme will only poorly converge with respect of the order of the quadrature. We propose a modified integration scheme to handle that issue. We apply the new technique developed to the estimation of stress intensity factors along the crack front of 3D cracks and use these SIFs for crack propagation using a Paris type fatigue law. [less ▲]

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See detailEmbryonic signals and pregnancy diagnosis in ruminants
Beckers, Jean-François ULg; Touati, Kamal ULg; Alvarez-Oxiley, A. V. et al

in Reproduction in Domestic Animals (2004), 39(4), 252

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See detailGraft-versus-tumor effects after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning
Baron, Frédéric ULg; Maris, Michael; Sandmaier, Brenda et al

in Blood (2004), 104

We have used a nonmyeloablative conditioning regimen consisting of 2 Gy total body irradiation +/– fludarabine, 30 mg/m²/day x 3 days, to condition elderly or ill patients (pts) with hematological ... [more ▼]

We have used a nonmyeloablative conditioning regimen consisting of 2 Gy total body irradiation +/– fludarabine, 30 mg/m²/day x 3 days, to condition elderly or ill patients (pts) with hematological malignancies for allogeneic hematopoietic cell transplantation (HCT). This approach relies almost exclusively on graft-versus-tumor (GVT) effects for control of malignancy. Here, we analyzed GVT effects in 322 pts with hematological malignancies given grafts from HLA-matched related (n=192) or unrelated (n=130) donors. Grades I, II, III and IV acute GVHD were seen in 26 (8.1%), 141 (43.8%), 34 (10.6%) and 11 (3.4%) pts, respectively. Extensive chronic GVHD was seen in 181 (56.2%) pts and of these, 64 (19.9%) cases had de novo chronic GVHD. Putative GVT effects were evaluated using time-dependent Cox regression models. Of the 221 pts with measurable disease at HCT, 126 (57%) achieved complete (n=98) or partial (n=28) remissions. Multivariate analysis identified chemosensitivity for B-cell malignancies (p=.02), and tandem autologous/allogeneic HCT (p=.04) as pre-transplant factors associated with higher probabilities of achieving complete remissions (CR) after HCT. After adjusting for these factors, acute GVHD of any grade was not found to be associated with an increased probability of achieving CR. There was a trend for a higher probability of achieving CR in pts with chronic GVHD (p=.07). Progression/relapse was observed in 108 pts. Multivariate analysis identified that lower disease-risk (p=.0004), tandem autologous/allogeneic HCT (p=.02) and adapted Charlson comorbidity index (CCI) score at transplant < 3 (p=.002) resulted in significantly decreased risk of progression/relapse. After correcting for these factors, extensive chronic GVHD was associated with a decreased risk of progression/relapse (p=.006). Pts with grade 1 acute GVHD tended to have less progression/relapse (p=.07). Conversely, grade II–IV acute GVHD did not significantly affect the risk of progression/relapse. Nonrelapse mortality was observed in 70 pts. Multivariate analysis showed that lower disease-risk (p=. 001), tandem autologous/allogeneic HCT (p=.002) and CCI score at transplant < 3 (p<.0001) significantly decreased nonrelapse mortality. After adjusting for these variables, grade II (p=.04) and grade III–IV (p<.0001) acute GVHD increased nonrelapse mortality while extensive chronic GVHD did not. The 3-year probability of progression-free survival (PFS) was 38.5%. In multivariate analysis, lower disease-risk (p<.0001), tandem autologous/allogeneic HCT (p=.0008) and CCI score at transplant < 3 (p<.0001) resulted in significantly better PFS. After adjusting for theses variables, grade 1 acute GVHD (p=.02) and chronic extensive GVHD (p=.003) were both associated with significantly better PFS, while grade III–IV acute GVHD (p<.0001) was associated with decreased PFS. In summary, chronic GVHD in pts given nonmyeloablative conditioning was associated with substantial GVT effects which led to improved PFS. Conversely, any potential GVT benefits from grade II–IV acute GVHD were offset by higher nonrelapse mortality resulting in worse PFS. Efforts should be directed at reducing the risk of grade II–IV acute GVHD while allowing de novo chronic GVHD for best PFS after allogeneic HCT with nonmyeloablative conditioning. [less ▲]

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See detailEffect of exercise on blood glutathione in healthy race horses
De Moffarts, Brieuc; Kirschvink, Nathalie; Art, Tatiana ULg et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailEffects of thiazolidinediones on tumor necrosis factor R alpha induced inflammatory cytokine expression
Desmet, Christophe ULg; Warsée, Barbara; Mélotte, D. et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailSTAT5 promotes granulocyte survival during inflammation
Fievez, Laurence ULg; Desmet, Christophe ULg; Pajak, B. et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailCeramides play a critical role in spontaneous neutrophil apoptosis
Seumois, G.; Fillet, Marianne ULg; Gillet, Laurent ULg et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailInfluence of chloride and phosphate on the binding of oxygen to canine and feline red blood cells
Cambier, Carole ULg; Wiernickx; Clerbaux, Th et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailCadmium-induced lung inflammation in rats is associated with an increase of matrix metalloproteinases-2 and -9 activity in broncho-alveolar lavage fluid
Vincke, G.; Kirschvink, Nathalie; Belleflamme, M. et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailOxygen consumption and blood oxygen transport in endotoxemic calves
Cambier, Carole ULg; Clerbaux, T.; Detry, B. et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailMelatonin can Phase Shift the Endogenous Circadian Rhythm of Heart Rate and its Variability
Vandewalle, Gilles ULg; Middleton, B; Rajaratnam, SW et al

in Journal of Sleep Research (2004), 13(Suppl. 1),

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See detailChronic cough in horses : environmental management and aerosol therapy
Art, Tatiana ULg

in Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere (2004), 32 (G)

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See detailEffect of elevated PCO2 on optical properties of the coccolithophorid Emiliania huxleyi grown under nitrate limitation
Denis, M.; Sciandra; Harlay, Jérôme ULg et al

in Cytometry. Part A : The Journal of the International Society for Analytical Cytology (2004), 59A(1), 105

Side scatter and red fluorescence properties of the coccolithophore Emiliania huxleyi were investigated by flow cytometry when NO3-limited continuous cultures were submitted to a CO2 partial pressure ... [more ▼]

Side scatter and red fluorescence properties of the coccolithophore Emiliania huxleyi were investigated by flow cytometry when NO3-limited continuous cultures were submitted to a CO2 partial pressure (pCO2) increase from 400 to 700 ppm. Cultures renewed at the rate of 0.5 d-1 and were submitted to saturating light level. pCO2 was controlled by bubbling CO2-rich or CO2- free air in the cultures. Most of the analyses were repeated 5 times and the average SD were < 1.6%, 0.1 and 0.2% for counting, fluorescence and side scatter respectively. Considering the possible decalcification induced by the increase of CO2 in the chemostat atmosphere, the maximum variation that can be expected for side scatter is that provided by the coccolith depletion upon acidification of the cell suspension. The acidification induced a large (36%) decrease of the side scatter signal but had no detectable effect on the red fluorescence. A control was run with a non-calcifying species, Dunaliella tertiolecta, where acidification induced no detectable change, both on fluorescence and side scatter. During the time of the experiment, the decline of side scatter in chemostat 1 never approached the potential 36% change observed when coccoliths are fully dissolved. Interestingly, the specific chl a fluorescence of E. huxleyi slightly increased during the period of high CO2 level. At the end of the experiment this increase amounted to a significant 2.8% of the initial signal. Furthermore, it progressed linearly with time over the period of observation. However, the experiment did not last enough to know if the fluorescence increase had already reached its maximum value. The acidification experiment supported the use of side scatter as a relevant parameter to trace potential changes in calcification. Since the estimated 25% decrease in calcification induced by the rise in CO2 atmosphere did not result in dramatic changes in side scatter values, we can conclude that the number of cocoliths and the overall shape and granulosity of cells was not significantly affected by this decrease. Changes must have only affected tiny structure details of the coccoliths which is supported by scanning electron microscopy observations. The small but significant increase of the fluorescence signal can be considered as a physiological response to the CO2 rise. This suggests a more dynamic photosynthetic process that would result in a higher rate of organic matter production providing that the system is not nutrient limited as in the present situation. [less ▲]

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See detailPlatelet expression of non-functional P2X1delL ion channels in mice reduces arterial thrombosis
Oury, Cécile ULg; Daenens, Kim; Feijge, Marion et al

in Haematologica (2004)

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See detailLevels of contamination for various pollutants present in Belgian human plasma
Van Wouwe, Nathalie; Covaci, Adrian; Kannan, Kurunthachalam et al

in Organohalogen Compounds (2004)

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See detailChronic mastitis-affected cows display lower lipoxin levels than acute mastitis-affected cows
Boutet, Philippe ULg; Bureau, Fabrice ULg; Degand, Guy ULg et al

in Recueil "Le Médecin Vétérinaire du Québec" (2004), 34(1 et 2), 160

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See detailInterleukin-1, interleukin-6 and oncostatin M stimulate normal subchondral osteoblasts to induce cartilage degradation
Sanchez, Christelle ULg; Deberg, Michelle ULg; Piccardi, Nathalie et al

in Osteoarthritis and Cartilage (2004), 12(Suppl. B), 98

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See detailEffects of interleukin-1 beta and dexamethasone on the expression by chondrocytes of antioxidant enzymes
Mathy, Marianne ULg; Devel, Philippe; Sanchez, Christelle ULg et al

in Osteoarthritis and Cartilage (2004), 12(Suppl. B), 51-52

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See detailBootstrap and the parameters of pion nucleon resonances
Semenov-Tyan-Shanskiy, Kirill ULg; Vereshagin, Alexander; Vereshagin, Vladimir

in AIP Conference Proceedings (2004), 717

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See detailMarkers of vitamin C and K-3 induced autoschizis of urologic tumors
Jamison, J; Gilloteaux, J; Taper, HS et al

in Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society (2004), 52

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See detailDevelopment of RT-PCR assays using fluorogenic 3 minor groove binder DNA probes for detection of fruit tree viruses.
Marbot, Sophie; Kummert, Jean; Vendrame, Marina et al

in Acta Horticulturae (2004), (657), 547-551

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See detailEnCOrE (Encyclopédie de Chimie Organique Electronique): an Original Way to Represent and Transfer Knowledge from Freshmen to Researchers in Organic Chemistry
Colaux, Catherine ULg; Krief, Alain

in Electronic Workshops in Computing (2003, December 03)

EnCOrE is an original proposal which is expected to allow to share and transfer knowledge in organic chemistry. The system will use MIDES a software, with a peer-to-peer architecture, which will allow to ... [more ▼]

EnCOrE is an original proposal which is expected to allow to share and transfer knowledge in organic chemistry. The system will use MIDES a software, with a peer-to-peer architecture, which will allow to set up a technological and methodological frame to allow collaborative building of knowledge in between chemists. Learning GRID's services will help for Experimental electronic laboratory "LabCOrE" as well as for predictive computational tools. [less ▲]

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See detailSoft tissue attachment formation at titanium abutments in humans: a new model
Rompen, Eric ULg; Domken, Olivier ULg; Lamy, Marc ULg et al

in Journal of Dental Research (2003, December), 82(Sp. Iss. C), 510

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See detailImpact du Percussionaire® et de la kinésithérapie respiratoire conventionnelle après chirurgie cardiaque : étude randomisée contrôlée
Kellens, Isabelle ULg; Fraipont, V.; Weber, T. et al

in Réanimation (2003, December), 12(suppl 3), 243

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See detailPharmacological evaluation of BM-573, a dual thromboxane A(2) receptor antagonist and thromboxane synthase inhibitor, as potential anti-metastatic agent
de Leval, X. J.; Dassesse, T.; Benoit, V. et al

in Blood (2003, November 16), 102(11, Part 2), 72

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See detailEvaluation of an osteoporosis screening campaign in the general population: does misclassification by screening test impact on the perception of the campaign?
Richy, Florent; Pire, G.; Maassen, P. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 68

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See detailUncoupling of bone formation and resorption with a novel oral formulation of salmon calcitonin in postmenopausal women
Tanko, L. B.; Bagger, Y. Z.; Devogelaer, Jean-Pierre et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 4

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See detailFive-year follow-up patients issued from a previous 3-year randomised, controlled trial of glucosamine sulfate in knee osteoarthritis
Bruyère, Olivier ULg; Compère, S.; Gathy, C. et al

in Osteoporosis International (2003, November), 14(Suppl 7), 9

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See detailEvaluation of a campaign for osteoporosis screening in the general population: what is the follow-up given by general practitioners to a positive screening result?
Richy, Florent; Pire, G.; Maassen, P. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 67

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See detailEvaluation of prevalence of osteoporosis and osteopenia in men presenting at multiple risk detection campaign
Hanssens, L.; De Ceulaer, F.; Tancredi, Annalisa ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 90

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See detailUse of healthcare resources related to gastrointestinal toxicity of NSAIDS
Rabenda, Véronique ULg; Belaiche, Jacques ULg; Raeman, F. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 14

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See detailEvaluation of the osteoporosis self-assessment tool (OST) as a screening test for osteoporosis and osteopenia in men
De Ceulaer, F.; Hanssens, L.; Tancredi, Annalisa ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 93

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See detailControlled whole body vibration to decrease fall risk and improve health related quality of life in elderly patients
Bruyère, Olivier ULg; Wuidart, M. A.; di Palma, E. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 63

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See detailRelief in mild-to-moderate pain is not a confounder in joint space narrowing assessment of full extension knee radiographs in recent osteoarthritis structure modifying drug trials
Pavelka, K.; Bruyère, Olivier ULg; Rovati, Lucio C et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 62-63

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