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See detailDevelopment of a full fiber-coupled laser ultrasound robotic system using two-wave mixing 1064 nm detection and 532 nm YAG generation
Vandenrijt, Jean-François ULg; Simar, Juan Felipe ULg; Thizy, Cédric ULg et al

in Laser Ultrasonics and Advanced Sensing (2015, June)

An all-fibered laser ultrasonic system for complex shape composite parts is presented. It is based on two-wave mixing detection and a long pulse laser working at 1064 nm and generation by a fibered YAG Q ... [more ▼]

An all-fibered laser ultrasonic system for complex shape composite parts is presented. It is based on two-wave mixing detection and a long pulse laser working at 1064 nm and generation by a fibered YAG Q-switch laser working at 532 nm. A compact optical head combining both beams is interfaced to a robot system for scanning. Some practical issues of this system are studied. [less ▲]

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See detail[18F]UCB-H as a new PET radiotracer for Synaptic vesicle protein 2A: A first clinical trial.
Bahri, Mohamed Ali ULg; Stifkens, M; Bastin, Christine ULg et al

in Tijdschrift voor Nucleaire Geneeskunde (2015, May 09), 37(3), 1457-1458

The synaptic vesicle protein 2A (SV2A) is widely distributed in the brain and has been demonstrated to be involved in vesicle trafficking. The critical role of SV2A in proper nervous system function is ... [more ▼]

The synaptic vesicle protein 2A (SV2A) is widely distributed in the brain and has been demonstrated to be involved in vesicle trafficking. The critical role of SV2A in proper nervous system function is shown, e.g., by the fact that it is a binding site and the primary mechanism of the antiepileptic drug levetiracetam. This drug has recently been suggested to reduce synaptic deficits in a mouse model for Alzheimer’s disease. We here aimed to investigate the cerebral distribution of [18F]UCB-H, which has a high affinity with the SV2A. Dynamic PET data of the head of 4 healthy volunteers were acquired over 100 minutes after injection of 170.4 ± 24.9 MBq of GMP produced [18F]UCB-H. The arterial input function (IF) was obtained by blood sampling but also derived from the dynamic data using the correlation coefficient method. Blood data revealed a consistent amount of [18F]UCB-H in whole blood and plasma indicating a very low degree of binding of the tracer to the red blood cells. The unchanged fraction of [18F]UCB-H in plasma showed a bi-exponential behavioral decrease with a starting fraction of 92% of the injected amount of the tracer, measured at 3 min post injection. This fraction decreased to about 50% at 10 min post injection. The image-derived arterial IFs showed to be very similar to the measured ones with a peak-ratio around 0.91 and an area-under-curve ratio about 0.98. The PET images showed a high and rapid uptake of [18F]UCB-H in the grey matter structures, matching the known ubiquitous distribution of the SV2A in the brain. The kinetics of the tracer in the brain was characterized by an initial high uptake phase followed by rapid washout. For the three standard compartmental models (1-tissue, 2-tissue, and Logan Plot), similar results were obtained with both the measured and image-derived IFs. Nevertheless the two-tissue compartment model fitted the experimental data best and provided a total distribution volume of the [18F]UCB-H in the brain greater than 7 mL/cm3 and a specific distribution volume around 3 mL/cm3. Our results suggest that [18F]UCB-H is a good candidate as radiotracer for brain SV2A proteins and could be used for human studies (dosimetry has already been reported elsewhere). Image-derived IF showed to be useful for quantitative studies without the need to the arterial blood sampling. This new tracer could help to assess SV2A modifications in neurological pathologies such as Alzheimer’s disease. [less ▲]

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See detailSujet de disputes ou objet de partage ? L’anthropologue au centre de conflits entre enfants de 5 à 8 ans (Liège, Belgique)
Campigotto, Marie ULg

in AnthropoChildren : Perspectives ethnographiques sur les enfants & l'enfance = Ethnographic Perspectives in Children & Childhood (2015, May 08)

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See detailTrace element contamination severity of coastal waters: A first bioassessment at the scale of the whole Mediterranean Sea
Richir, Jonathan ULg; Salivas-Decaux, Maylis; Lafabrie, Céline et al

in PeerJ (2015, May)

Human activities generate large volumes of waste that supply marine coastal environments in pathogens, organic matter, nutrients and toxicants. Among the wide range of toxicants are trace elements. Since ... [more ▼]

Human activities generate large volumes of waste that supply marine coastal environments in pathogens, organic matter, nutrients and toxicants. Among the wide range of toxicants are trace elements. Since the latter are toxic for aquatic organisms from threshold levels and as they are therefore likely to cause multiple damage to the population, the community and the ecosystem levels, their environmental occurrence has to be accurately monitored in order to guarantee appropriate environmental management of coastal zones and to preserve marine coastal ecosystems and the goods and services they provide. In the framework of the STARECAPMED project, the present study aimed to monitor, for the first time, the coastal contamination of the entire Mediterranean by As, Ag, Cd, Cu, Hg, Ni and Pb, using Posidonia oceanica (L.) Delile as bioindicator species. But sustainable coastal management also requires the development of appropriate contamination classification systems intended, among other purposes, for environmental managers and policy makers. The combined utilization of several complementary monitoring tools, i.e. water quality scale, pollution index (TEPI and TESVI) and spatial analysis (PCA, CA, correlation analysis and GIS mapping) successfully led to the development of an operational classification system of this kind. In particular, the mapping of the trace element contamination according to a new proposed 5-level water quality scale using the quantile method precisely outlined the contamination severity along Mediterranean coasts and facilitated interregional comparisons. The reliability of the use of P. oceanica as bioindicator species was further again demonstrated through several global, regional and local detailed case studies. In conclusion, holistic approaches such as developed in the present study should be privileged to accurately monitor the contamination rate of coastal waters and to transfer relevant information on this composite problem to environmental managers and policy makers. [less ▲]

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See detailOne-year Prevalence of Migraine Using a Validated Extended French Version of the ID MigraineTM: a Belgian Population-Based Study
Schoenen, Jean ULg; Streel, Sylvie ULg; Donneau, Anne-Françoise ULg et al

in Cephalalgia : An International Journal of Headache (2015, May), 35(6), 155-156

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See detailA consensual Diving-PAM protocol to monitor Posidonia oceanica photosynthesis
Gobert, Sylvie ULg; Lepoint, Gilles ULg; Silva, João et al

in PeerJ Preprints (2015, May)

The seagrass Posidonia oceanica is widely recognized as an effective bioindicator of the health status of Mediterranean coastal waters. Chlorophyll fluorescence measurements, in particular through the ... [more ▼]

The seagrass Posidonia oceanica is widely recognized as an effective bioindicator of the health status of Mediterranean coastal waters. Chlorophyll fluorescence measurements, in particular through the Pulse Amplitude Modulated (PAM) fluorometry method, are performed to study aquatic plant ecology and vitality and to assess their responses to diverse stressful factors. However, the current understanding of P. oceanica photosynthetic responses to environmental stresses does only allow scientists to use the PAM-method as a complementary tool to other more-robust monitoring techniques. Consequently, a more in-depth knowledge of the natural causes of variability of P. oceanica photosynthetic responses are a prerequisite to any surveys relying on that time and cost-effective method. In the framework of the STARECAPMED project, this work aimed to determine the influence of several environmental (depth, daytime, season) and plant-specific characteristics (leaf age, leaf part analyzed, epiphytic coverage) on the photosynthetic responses (Y, ETR, RLC) of P. oceanica. Water temperature, irradiance and several biochemical parameters of the seagrass (chl.a, chl.b, C, N, P, micronutrients such as Fe, Cu) were measured as well. The field survey was performed in a pristine meadow in the Calvi Bay, Corsica. Environmental and plant-physiological characteristics deeply influenced P. oceanica photosynthetic responses. As an example, ETR decreased with depth, contrary to Y that mostly increased. ETR was lower in the basal part of leaf blade, and the epiphytic coverage of leaf tips slightly increased their ETR compared to leaf tips cleaned of epiphytes. Depth and leaf part-related variations in RLC were also observed. Because of this natural variability, it appears essential to develop a consensual protocol of chlorophyll fluorescence measurements to publish reliable and comparable results between studies. We therefore notably suggest to perform measurements close to midday, when photosynthetic responses are the highest; at 10-15 m depth in order to avoid, among others, low depth light irradiance variability; on the middle part of the 3rd-4th external leaf, well developed, highly photosynthetic, and little epiphyted. Finally, because P. oceanica fluorescence was correlated with N, P and chl.b leaf contents, the PAM-method could afterwards be used as bioindicator technique, according to the protocol proposed. [less ▲]

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See detailThird-party mesenchymal stem cell infusion in kidney transplant recipient: 6-month safety interim analysis
WEEKERS, Laurent ULg; ERPICUM, Pauline ULg; DETRY, Olivier ULg et al

in American Journal of Transplantation (2015, May), 15(suppl 3),

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See detailHigh output [18F]FDOPA on AllInOne (Trasis) at commercial scale
Otabashi, Muhammad; Cascione, Christian; Lemaire, Christian ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (2015, May), 58

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See detailA phase 1b study of Trebananib plus Paclitaxel and Trastuzumab or Capecitabine and Lapatinib in patients with HER2+ locally recurrent or metastatic breast cancer
Kaufman, P.A.; Freyer, G.; Kemeny, M. et al

in Cancer Research (2015, May), 75(9), 5-19-14

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See detailNew Continuous Control Methodology for Nonlinear Dynamical Systems with Uncertain Parameters
Cho, Hancheol ULg; Wanichanon, Thanapat; Udwadia, Firdaus

in International Conference on Uncertainty Quantification in Computational Sciences and Engineering (2015, May)

This paper presents a new reference-tracking control methodology for nonlinear dynamical systems in the presence of unknown, but bounded, uncertainties in the system. To this end, two controllers are ... [more ▼]

This paper presents a new reference-tracking control methodology for nonlinear dynamical systems in the presence of unknown, but bounded, uncertainties in the system. To this end, two controllers are combined. A nonlinear controller is first developed to exactly track the desired reference trajectory assuming no uncertainties in the nonlinear nominal system. The entire nonlinear dynamics of the nominal system is included and no approximations / linearizations are made. Next, an additional continuous controller is developed in closed form to compensate for uncertainties in the physical model by generalizing the concept of sliding surfaces. Unlike conventional sliding mode control, this Lyapunov-based approach eliminates the chattering problem by replacing a signum function with a set of continuous functions that may have different forms depending on practical considerations related to actuator implementation. Among these possible forms, special attention is paid to a controller with a PID form. By using Lyapunov stability theory it is shown that this additional controller forces the tracking errors that arise because of the uncertainties in the system to move into a small, user-specified region around the generalized sliding surface. Once these tracking errors enter this small region, if the original nonlinear system is assumed to be linearizable, then linear control theory will ensure that they will further converge to even smaller values. A numerical example is provided, in which a satellite in the presence of air drag is required to maintain a specific, circular orbit around the Earth whose gravity field is imprecisely known. The example demonstrates the accuracy, efficiency, and ease of implementation of the control methodology. [less ▲]

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See detailSeagrasses or caged mussels to bioassess the contamination rate of Mediterranean coastal waters? That is the question
Richir, Jonathan ULg; Galgani, François; Benedicto, José et al

in PeerJ (2015, May)

Biological indicators have the capacity to integrate the temporal changes of contaminants, concentrations or fluxes over various time-scales, and are thus considered as interesting tools for water quality ... [more ▼]

Biological indicators have the capacity to integrate the temporal changes of contaminants, concentrations or fluxes over various time-scales, and are thus considered as interesting tools for water quality biomonitoring. Since the mid-70ies, French programs have developed water monitoring approaches based on the use of bivalve molluscs; and recently the natural background and the extent of water contamination were bioassessed at the scale of the whole western Mediterranean. But even if bivalve molluscs are viewed as reliable bioindicators, their use is not always made easy as a result of their absence in numerous coastal regions that force their transplantation (cages) during several months before their sampling and analysis. This weakness led several scientists to evaluate the bioindicator abilities of other marine organisms. Seagrasses, whose ability to bioaccumulate contaminants proportionally to environmental contamination levels has been clearly demonstrated, have thus been proposed as an appropriate alternative tool for coastal water quality assessment. Very little studies have however so far considered the combined utilization of these two groups of bioindicator organisms, i.e. caged bivalve molluscs and seagrasses. In the framework of the STARECAPMED project, we therefore compared and discussed the bioaccumulation of trace elements in the Neptune grass Posidonia oceanica and in caged Mediterranean mussels Mytilus galloprovincialis. The sampling was performed at the scale of the western Mediterranean. The two species told two contamination stories which, although sometimes different, showed to be complementary. P. oceanica and M. galloprovincialis bioaccumulated dissolved trace elements from the water column and thus provided information regarding trace element contamination severity integrated over several days to a few months. Seagrasses, strongly rooted in the sediments, reflected the long-term exposure to trace elements since sediments offer a degree of time integration over several years to decades. Caged mussels, as filter feeder artificially maintained in the water column, bioaccumulated trace elements from their particulate phase, and therefore gave valuable information regarding continental-terrigenous inputs to coastal waters. In conclusion, seagrasses and mussels should neither supplant, nor substitute, but rather complement each other in order to provide the full time- and space-integrated coastal contamination story of the Mediterranean. [less ▲]

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See detailUPLC®-MS/MS, an analytical tool for the accurate and rapid quantification of phytoestrogen metabolites in milk
Daems, Frédéric ULg; Jasselette, Christophe; Romnee, Jean-Michel et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2015, April 17), 19(2), 121-122

The term ‘phytoestrogen’ is used to define a wide variety of nonsteroidal compounds that occur naturally in many plants. When they are absorbed by cows, these polyphenolic compounds undergo ... [more ▼]

The term ‘phytoestrogen’ is used to define a wide variety of nonsteroidal compounds that occur naturally in many plants. When they are absorbed by cows, these polyphenolic compounds undergo biotransformation by specific bacteria present in the gastrointestinal tract. The resulting metabolites are absorbed in the organism and some are excreted in milk. The impact of these compounds on human health divides opinion. Some scientists believe that they might have adverse health effects. Others believe the opposite, especially with regard to their microbial metabolites, such as equol. Whatever one's view on the subject, scientists need accurate, sensitive and rapid analytical methods in order to continue the research on clarifying the phytoestrogen issue. Cow's milk is an animal product that is common in the human diet, and it is therefore important to evaluate its content of phytoestrogen metabolites. In order to study the human intake of equol via commercial milk, an analytical method was developed and validated following EMA/CVMP/VICH/463202/2009 guidelines. Enzymatic hydrolysis was used to release the equol. It was then extracted using double liquid/liquid extraction and analyzed using UPLC®-MS/MS, with an analysis runtime of only 5 min. This analytical method produced a linear calibration curve with a high correlation coefficient (R2≥0.996) between 5 and 1,000 ng mL−1. Good intra- and inter-day precision (RSDs≤5.3% and ≤5.2%, respectively) and accuracy (bias≤8.6%) were achieved. The recovery rate differed slightly among the different types of milk, ranging between 60.6±1.09% and 82.3±5.21%. Good method repeatability was observed (RSDs<15%). There was neither a matrix effect nor a carry-over effect, and the sample extracts were stable during storage for at least 7 days at −21°C and 5°C. In order to apply the proposed method and obtain an initial estimate of equol concentration in cow’s milk in Belgium, 44 samples of various brands found in several supermarkets and 5 raw milk samples from Walloon farms were analyzed. Equol was found in all the samples analyzed, with a concentration ranging from 10 to 50 ng mL−1 for conventional milk and from 70 to 130 ng mL−1 for organic milk. These results were compared with other European studies and the same trend was observed. The results obtained show the specificity, sensitivity and precision of this method for analyzing oestrogenic metabolite-equol in cow’s milk. This study should be extended to include a greater number of samples and be implemented over a longer period to see if there is a correlation between livestock practice and/or sample origins with the equol content in milk. The addition of other phytoestrogen compounds with this method, using UPLC®-MS/MS technology, could also lead to more reliable monitoring of these compounds in dairy production. [less ▲]

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See detailRetrieval of ammonia from ground-based FTIR measurements and its use for validation of satellite observations by IASI
Dammers, E; Palm, M; Warneke, T et al

in Geophysical Research Abstracts (2015, April 13), 17

Atmospheric Ammonia (NH3) has a major impact on human health and ecosystem services and plays a major role in the formation of aerosols [Erisman et al.,2013; Paulot and Jacob 2014]. NH3 concentrations are ... [more ▼]

Atmospheric Ammonia (NH3) has a major impact on human health and ecosystem services and plays a major role in the formation of aerosols [Erisman et al.,2013; Paulot and Jacob 2014]. NH3 concentrations are highly variable in space and time with overall short lifetime due to deposition and aerosol formation. The global atmospheric budget of nitrogen and in turn NH3 is still uncertain which asks for more ground-based and satellite observations around the world. Recent papers have described the possibility to measure NH3 with satellite infrared sounders which open up the way for calculations of global and regional nitrogen budgets [Clarisse et al 2009,Van Damme et al 2014a]. Validation of the satellite observations is essential to determine the uncertainty in the signal and its potential use. So far available surface layer observations of atmospheric NH3 concentrations have been used for comparisons with total columns retrieved from satellite observations [Van Damme 2014b]. We developed a retrieval for NH3 column density concentrations (molecules NH3/cm2) by fitting a set of spectral windows to ground-based solar absorption Fourier transform infrared (FTIR) measurements with the spectral fitting program SFIT4 [Hase et al., 2004]. The retrieval is then applied to FTIR measurements from a set of spectrometer sites from the Network for detection of Atmospheric Composition Change (NDACC) to retrieve NH3 columns for the sites located in Bremen, Germany; Lauder, New Zealand; Jungfraujoch, Switzerland; and the island of Reunion, France. Using eight years (2005-2013) of retrieved NH3 columns clear seasonal cycles are observed for each of the stations. Maximum concentrations can be related to NH3 emission sources, specific for the regions. A comparison between the retrieved NH3 columns and observations from the recent IASI- NH3 product [Van Damme et al, 2014a] using strict spatial and temporal criteria for the selection of observations showed a good correlation (R=0.82; slope=0.63). The IASI- NH3 columns for the Bremen and Lauder area show similar temporal cycles when compared to the FTIR observations. [less ▲]

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See detailHalogenated source gases measured by FTIR at the Jungfraujoch station: updated trends and new target species
Mahieu, Emmanuel ULg; Bader, Whitney ULg; Bovy, Benoît ULg et al

in Geophysical Research Abstracts (2015, April 13), 17

In this contribution, we present decadal time series of halogenated source gases monitored at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl) with Fourier Transform Infared (FTIR ... [more ▼]

In this contribution, we present decadal time series of halogenated source gases monitored at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl) with Fourier Transform Infared (FTIR) spectrometers, within the framework of the Network for the Detection of Atmospheric Composition Change. Total column trends presented in previous studies for CFC-11, -12 and HCFC-22, CCl4, HCFC-142b, CF4 and SF6 will be updated using the latest available Jungfraujoch solar observations. Investigations dealing with the definition of approaches to retrieve additional halogenated source gases from FTIR spectra will also be evoked. Our trend results will be critically discussed and compared with measurements performed in the northern hemisphere by the in situ networks. [less ▲]

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See detailIndividual variation of gait characteristics along a 500 meter walk in people with multiple sclerosis and healthy volunteers
Phan-Ba, Rémy; Pierard, Sébastien ULg; Giet, Amaury et al

in Multiple Sclerosis Journal (2015, April 10), 21(4), 532-533

Background: we previously demonstrated the usefulness of the Deceleration Index (DI, the ratio between the last 100m of the Timed 500-Meter Walk test –T500MW – and the walking speed - WS – of the Timed 25 ... [more ▼]

Background: we previously demonstrated the usefulness of the Deceleration Index (DI, the ratio between the last 100m of the Timed 500-Meter Walk test –T500MW – and the walking speed - WS – of the Timed 25-Foot Walk Test with a propelled start – T25FW+) to evaluate motor fatigue over a long walking distance in people with multiple sclerosis (pwMS). We also recently designed and internally validated a new gait analysis tool for pwMS (GAIMS) that can measure other relevant gait characteristics than the sole WS, such as ataxia, asymmetry and perhaps spasticity. Aims: (i) To compare various gait characteristics between the last and the first 100m of the T500MW in a population of pwMS and healthy volunteers (HV), (ii) to compare the ratio between the last and the first 100m of the T500MW with the DI, and (iii) their relationship with the EDSS. Methods : Subjects were asked to perform the T25FW+ and the T500MW as part of a multimodal evaluation at the MS Clinic of the CHU of Liège. Their gait characteristics were measured using GAIMS. (i) Paired Student’s t-tests were performed on various gait characteristics extracted during the last and first 100m of the T500MW with .05 as a level of significance, (ii) Spearman correlation coefficient (ρ) was calculated (ii) between these ratio and (iii) subject’s EDSS. Results: Seventy-one pwMS and 129 were enrolled in our study. (i) Significant differences were observed for speed related gait characteristics between the last and first 100m of the T500MW, but also for gait characteristics related to ataxia and precision of foot placement. (ii) A moderate positive correlation was observed between the WS ratio of the last and first 100m of the T500MW and the DI. (iii) The correlation between the DI and the EDSS was weakly negative, while the one between the last and first 100m of the T500MW ratio and the EDSS was moderatly negative. Conclusion: (i) As previously demonstrated, we here confirm that alongside to WS, there are other gait features affected by locomotor fatigue over a long walking distance, (ii) the moderate positive correlation between the DI and the last/first 100m of the T500MW indicates that these measures are not the same and that next to a long distance walking test such as the T500MW, a short one such as the T25FW+ remains useful. (iii) The last/first 100m of the T500MW is better correlated to the EDSS and might be a better predictive tool of pwMS’ neurologic state than the DI. [less ▲]

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See detailBaseline Fibulin3 concentrations are associated with incidence of clinical knee OA after 30 months in overweight and obese women
Runhaar, Jos; Sanchez, Christelle ULg; Henrotin, Yves ULg et al

in Osteoarthritis and Cartilage (2015, April), 23(S2), 83

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See detailThe CROSTVOC project – an integrated approach to study the effect of stress on BVOC exchange between agricultural crops and grassland ecosystems and the atmosphere
Amelynck, Crist; Heinesch, Bernard ULg; Aubinet, Marc ULg et al

in Geophysical Research Abstracts (2015, April), 17

Global changes in atmospheric composition and climate are expected to affect BVOC exchange between terrestrial vegetation and the atmosphere through changes in the drivers of constitutive BVOC emissions ... [more ▼]

Global changes in atmospheric composition and climate are expected to affect BVOC exchange between terrestrial vegetation and the atmosphere through changes in the drivers of constitutive BVOC emissions and by increases in frequency and intensity of biotic or abiotic stress episodes. Indeed, several studies indicate changes in the emission patterns of constitutive BVOCs and emission of stress-induced BVOCs following heat, drought and oxidative stress, amongst others. Relating changes in BVOC emissions to the occurrence of one or multiple stressors in natural environmental conditions is not straightforward and only few field studies have dealt with it, especially for agricultural crop and grassland ecosystems. The CROSTVOC project aims to contribute in filling this knowledge gap in three ways. Firstly, it aims at performing long-term BVOC emission field measurements from maize (Zea mays L.) and wheat (Triticum aestivum L.), two important crop species on the global scale, and from grassland. This should lead to a better characterization of (mainly oxygenated) BVOC emissions from these understudied ecosystems, allowing a better representation of those emissions in air quality and atmospheric chemistry and transport models. BVOC fluxes are obtained by the Disjunct Eddy Covariance by mass scanning (DEC-MS) technique, using a hs-PTR-MS instrument for BVOC analysis. Secondly, the eddy covariance BVOC flux measurements (especially at the grassland site) will be accompanied by ozone flux, chlorophyll fluorescence, photosynthesis and soil moisture measurements, amongst others, to allow linking alterations in BVOC emissions to stress episodes. Simultaneously, automated dynamic enclosures will be deployed in order to detect specific abiotic and biotic stress markers by PTR-MS and identify them unambiguously by GC-MS. Thirdly, the field measurements will be accompanied by laboratory BVOC flux measurements in an environmental chamber in order to better disentangle the responses of the BVOC emissions to driving factors that co-occur in field conditions and to determine the influence of single abiotic stressors on BVOC emissions. Next to a general presentation, some preliminary results of the project will be shown. [less ▲]

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See detailGAIMS: a tool specifically developed for the clinical gait analysis of patients with multiple sclerosis
Pierard, Sébastien ULg; Phan-Ba, Rémy; Giet, Amaury et al

in Multiple Sclerosis Journal (2015, April), 21(4), 498-499

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See detailWolff’s Law and the Interplay between Bone Structure and External Loading
Ruffoni, Davide ULg; Christen, Patrik; Scherf, Heike et al

in IBMS BoneKEy (2015, April), 13

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See detailFacteurs génétiques et risque de dysglycémie dans des familles de diabétiques de type 2: l’étude DESCENDANCE
Franc, S; Cauchi, S; Yengo, L et al

in Diabètes & Métabolism (2015, April), 41(s1), 10-35

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See detailAssessment of damage and anisotropic plasticity models to predict Ti-6Al-4V behavior
Guzmán Inostroza, Carlos Felipe ULg; Tuninetti, Víctor; Gilles, Gaëtan ULg et al

in Key Engineering Materials [=KEM] (2015, April), 651-653

The plastic behavior of the Ti-6Al-4V alloy includes several features as strength differential effect, anisotropy and yield strength sensitivity to temperature and strain rate. Monotonic tensions in the ... [more ▼]

The plastic behavior of the Ti-6Al-4V alloy includes several features as strength differential effect, anisotropy and yield strength sensitivity to temperature and strain rate. Monotonic tensions in the three orthogonal directions of the material are performed to identify the Hill ’48 yield criterion. Monotonic compression and plane strain tensile tests are also included in the experimental campaign to identify the orthotropic yield criterion of CPB06. An assessment of the two models is done by comparing the yield loci and the experimental data points for different levels of plastic work. A first approach of the damage modelling of the Ti-6AL-4V alloy is investigated with an extended Gurson-Tvergaard-Needleman damage model based on Hill ’48 yield criterion. Finite element simulations of the experiments are performed and numerical results allows checking force-displacement curves until rupture and local information like displacement and strain fields. The prediction ability of the Hill ’48, CPB and extended Gurson models are assessed on simple shear and notched tensile tests until fracture. [less ▲]

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See detailBiogenic Volatile Organic Compound (BVOC) emissions from agricultural crop species: is guttation a possible source for methanol emissions following light/dark transition?
Mozaffar, Ahsan ULg; Amelynck, Crist; Bachy, Aurélie ULg et al

in Geophysical Research Abstracts (2015, April), 17(EGU2015-2110-1),

In the framework of the CROSTVOC (CROp STress VOC) project, the exchange of biogenic volatile organic compounds (BVOCs) between two important agricultural crop species, maize and winter wheat, and the ... [more ▼]

In the framework of the CROSTVOC (CROp STress VOC) project, the exchange of biogenic volatile organic compounds (BVOCs) between two important agricultural crop species, maize and winter wheat, and the atmosphere has recently been measured during an entire growing season by using the eddy covariance technique. Because of the co-variation of BVOC emission drivers in field conditions, laboratory studies were initiated in an environmental chamber in order to disentangle the responses of the emissions to variations of the individual environmental parameters (such as PPFD and temperature) and to diverse abiotic stress factors. Young plants were enclosed in transparent all-Teflon dynamic enclosures (cuvettes) through which BVOC-free and RH-controlled air was sent. BVOC enriched air was subsequently sampled from the plant cuvettes and an empty cuvette (background) and analyzed for BVOCs in a high sensitivity Proton-Transfer Reaction Mass Spectrometer (hs-PTR-MS) and for CO2 in a LI-7000 non-dispersive IR gas analyzer. Emissions were monitored at constant temperature (25 °C) and at a stepwise varying PPFD pattern (0-650 µmol m-2 s-1). For maize plants, sudden light/dark transitions at the end of the photoperiod were accompanied by prompt and considerable increases in methanol (m/z 33) and water vapor (m/z 39) emissions. Moreover, guttation droplets appeared on the sides and the tips of the leaves within a few minutes after light/dark transition. Therefore the assumption has been raised that methanol is also coming out with guttation fluid from the leaves. Consequently, guttation fluid was collected from young maize and wheat plants, injected in an empty enclosure and sampled by PTR-MS. Methanol and a large number of other compounds were observed from guttation fluid. Recent studies have shown that guttation from agricultural crops frequently occurs in field conditions. Further research is required to find out the source strength of methanol emissions by this guttation phenomenon in real environmental conditions. [less ▲]

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See detailImproving energy partitioning and the nighttime energy balance by implementation of a multi-layer energy budget in ORCHIDEE-CAN
Chen, Yiying; Ryder, James; Naudts, Kim et al

in Geophysical Research Abstracts (2015, April), 17

Canopy structure is one of the most important vegetation characteristics for land-atmosphere interactions as it determines the energy and scalar exchanges between land surface and overlay air mass. In ... [more ▼]

Canopy structure is one of the most important vegetation characteristics for land-atmosphere interactions as it determines the energy and scalar exchanges between land surface and overlay air mass. In this study we evaluated the performance of a newly developed multi-layer energy budget (Ryder et al., 2014) in a land surface model, ORCHIDEE-CAN (Naudts et al., 2014), which simulates canopy structure and can be coupled to an atmospheric model using an implicit procedure. Furthermore, a vertical discrete drag parametrization scheme was also incorporated into this model, in order to obtain a better description of the sub-canopy wind profile simulation. Site level datasets, including the top-of-the-canopy and sub-canopy observations made available from eight flux observation sites, were collected in order to conduct this evaluation. The geo-location of the collected observation sites crossed climate zones from temperate to boreal and the vegetation types included deciduous, evergreen broad leaved and evergreen needle leaved forest with maximum LAI ranging from 2.1 to 7.0. First, we used long-term top-of-the-canopy measurements to analyze the performance of the current one-layer energy budget in ORCHIDEE-CAN. Three major processes were identified for improvement through the implementation of a multi-layer energy budget: 1) night time radiation balance, 2) energy partitioning during winter and 3) prediction of the ground heat flux. Short-term sub-canopy observations were used to calibrate the parameters in sub-canopy radiation, turbulence and resistances modules with an automatic tuning process following the maximum gradient of the user-defined objective function. The multi-layer model is able to capture the dynamic of sub-canopy turbulence, temperature and energy fluxes with imposed LAI profile and optimized parameter set at a site level calibration. The simulation result shows the improvement both on the nighttime energy balance and energy partitioning during winter and presents a better Taylor skill score, compared to the result from single layer simulation. The importance of using the multi-layer energy budget in a land surface model for coupling to the atmospheric model will also be discussed in this presentation. [less ▲]

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See detailMeasuring and modelling the intra-day variability of the CO2 & CO2 vertical soil profile production in a Scots pine forest
Longdoz, Bernard ULg; Goffin, Stéphanie; Parent, Florian et al

in Geophysical Research Abstracts (2015, April), 17

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See detailDiurnal and seasonal variability of CO2 fluxes over a degraded Woodland under a Sudanian climate in Northern Benin (West Africa)
Ago, Expédit Evariste ULg; Serça, Dominique; Agbossou, Euloge Kossi et al

in Geophysical Research Abstracts (2015, April), 17

Turbulent CO2 exchanges over a degraded woodland were measured during 17 months (from November 2005 to March 2007) by an eddy-covariance system at Nangatchori in the northern part of Benin, West Africa ... [more ▼]

Turbulent CO2 exchanges over a degraded woodland were measured during 17 months (from November 2005 to March 2007) by an eddy-covariance system at Nangatchori in the northern part of Benin, West Africa. The site (Lat 9.65°N, Long 1.74°E, Alt: 432 m), under a Sudanian climate, is one of the sites that were equipped in the framework of the international AMMA-CATH program. The site was highly disturbed during preceding years by illegal tree logging, agricultural activities, cattle pasture, and bushfire. The footprint area is mainly formed by herbs and crops with some sparse shrubs and trees. Fluxes data were completed during the same period by meteorological measurements made at the Nalohou site located approximately 20 km from Nangatchori, and by an inventory of dominating species on 1km2 area around the tower during the wet season. Fluxes response to climatic variables was analyzed. The annual drought and moisture cycle was found to be the main controlling factor of the ecosystem dynamics. A very clear response of CO2 fluxes to PPFD appears, but is different according to seasons. During wet season, CO2 uptake increases with increasing PPFD following a typical curvilinear function and saturates for high PPFD (PPFD > 1000 µmol m-2 s-1), while during dry season, a very weak linear response of CO2 fluxes was observed. No clear dependency of the total ecosystem respiration on temperature was observed. At an annual scale (from November 1st 2005 to October 31st 2006), net carbon sequestered by the ecosystem was 18 +- 5 g C m-2. Finally, with respect to the water use the ecosystem appeared to be more efficient during morning and wet season than during afternoon and dry period. [less ▲]

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See detailConjonctivite néonatale à Neisseria Gonorrhoeae: pas seulement du passé
Tribolet, Sophie; Lefevre, Annabelle; Gillard, Perrine et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March 13), 17(1), 113

L’ophtalmie néonatale n’appartient pas qu’au passé, l’incidence d’infections à Neisseria Gonorrhaea étant en augmentation en Belgique. Différentes prophylaxies sont proposées (nitrate d’argent, povidone ... [more ▼]

L’ophtalmie néonatale n’appartient pas qu’au passé, l’incidence d’infections à Neisseria Gonorrhaea étant en augmentation en Belgique. Différentes prophylaxies sont proposées (nitrate d’argent, povidone iodine, tétracycline, érythromycine, acide fusidique), avec leurs avantages et inconvénients respectifs. Aucun consensus clair n’est établi quant à la solution la plus efficace, certains remettant en doute leur utilisation dans les pays développés. [less ▲]

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See detailL'histiocytose de Langerhans, une cause rare de Blueberry Muffin Syndrome
Kreins, Nathalie; Kalenga, Masendu ULg; RIGO, Vincent ULg

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March 12), 17(1), 72

La présentation du Blueberry Muffin Syndrome est typique, et permet de rapidement orienter le bilan étiologique. La biopsie cutanée est importante pour établir le diagnostic, qui lui-même conditionne le ... [more ▼]

La présentation du Blueberry Muffin Syndrome est typique, et permet de rapidement orienter le bilan étiologique. La biopsie cutanée est importante pour établir le diagnostic, qui lui-même conditionne le pronostic. [less ▲]

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See detailImplementation of placental transfusion protocol
Lefebvre, Caroline; MASSON, Véronique ULg; Kalenga, Masendu ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March 12), 17(1), 72

A clear protocol for placental transfusion gives the opportunity to improve care of preterm infants. Initial information session and simulation practice for medical and midwifes staffs helps with its ... [more ▼]

A clear protocol for placental transfusion gives the opportunity to improve care of preterm infants. Initial information session and simulation practice for medical and midwifes staffs helps with its implementation. Delayed clamping and cord milking are not difficult after a learning phase like for most new procedures. [less ▲]

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See detailUltra-low power microsystems integrated
Laurent, Philippe ULg; Dupont, François ULg; Stoukatch, Serguei ULg et al

in Conference proceedings (2015, March 11)

Microsys has developed wireless microsystems using off-the-shelf components comprising ultra-low power sensors such as temperature, humidity and luminosity. We will show how to make the microsystem more ... [more ▼]

Microsys has developed wireless microsystems using off-the-shelf components comprising ultra-low power sensors such as temperature, humidity and luminosity. We will show how to make the microsystem more compact by decreasing the power consumption. So doing, no or little maintenance is required, leading to an efficient Wireless Sensor Network (WSN). [less ▲]

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See detailImpact of intensive enteral nutrition in association with corticosteroïds in the treatment of severe alcoholic hepatitis: a multicenter randomized controlled trial
Moreno, C; Trepo, E; Louvet, A et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 01

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See detailExpel: a novel non-destructive method for mining soluble tumor biomarkers
Costanza, B; Blomme, A; MUTIJIMA NZARAMBA, Eugène ULg et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 13

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See detailAvancement du projet de l'inventaire typologique et dendrochronologique des charpentes anciennes en région Bruxelles-Capitale
Weitz, Armelle ULg; Charruadas, Paulo ULg; Crémer, Sarah et al

in Archaeologia Mediaevalis (2015, March), 38

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See detailMulticenter Belgian experience of sofosbuvir (medical need program) in very difficult-to-treat HCV patients: safety and efficacy results.
Degre, D; Laleman, W; Verhelst, X et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 03

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See detailRemboursement de la mesure continue du glucose en Belgique: un exemple de multidisciplinarité
RADERMECKER, Régis ULg; Contessi, El

in Diabètes & Métabolism (2015, March), 41

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See detailAnalyse rétrospective des données concernant les patientes avec diabète gestationnel au CHU de Liège
RADERMECKER, Régis ULg; PHILIPS, Jean-Christophe ULg; Sepulchre, E

in Diabètes & Métabolism (2015, March), 41

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See detailInfusion of third-party mesenchymal stream cells after liver transplantation: a phase-1, open-label, clinical study
DETRY, Olivier ULg; VANDERMEULEN, Morgan ULg; DELBOUILLE, Marie-Hélène ULg et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 29

Background: Mesenchymal stromal cells (MSC) are multipotent bone marrow progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed ... [more ▼]

Background: Mesenchymal stromal cells (MSC) are multipotent bone marrow progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. Patients & Methods: Clinical grade MSCs were locally collected from the bone marrow of unrelated healthy donors. They were cultured in a GMP-compliant lab, underwent extensive quality controls and were frozen for storage in a MSC bank. When needed for patient treatment, MSC were thawed and intravenously injected into patients. 10 liver transplant recipients under standard immunosuppression (TAC-MMF-low dose steroids until day 30) received 1.5-3x106/kg MSC on post-operative day 3±2. These patients were prospectively compared to a group of 10 control (MSC-) liver recipients. Primary endpoints were MSC infusion toxicity, and incidence of cancer and opportunistic infections at month 6. Secondary endpoints were patient and graft survivals and rejection at month 6, as well as the effects of MSC on recipients’ immune function and on immunohistology of at month 6 graft biopsies. Results: No MSC infusional toxicity was observed. Both groups were comparable in terms of donor and recipient characteristics. There was no difference in primary end-points between control and MSC groups. No patient developed de novo cancer. There was no statistical difference in patient and graft survivals or in rejection rates. There was no graft rejection in the MSC group. Month-6 graft biopsies were not different according to Banff and fibrosis scores. Discussion: This phase 1 study showed excellent tolerability and safety of a single infusion of third-party MSC after liver transplantation. There were no graft safety issues and no excess of immunosuppression after MSC injection. Further analyses of consequences of MSC injection on the immune profile are needed. The possibility of avoiding calcineurin-inhibitors with repeated MSC injections as main immunosuppressive therapy and/of tolerance induction by MSC infusion should be investigated by further studies. [less ▲]

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See detailMultitasking abilities in persons diagnosed with schizophrenia: a new tool and cognitive model.
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Laroi, Frank ULg

in Schizophrenia Bulletin (2015, March), 41(Supplement 1),

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities (Semkovska et al., 2010). Multitasking refers to ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities (Semkovska et al., 2010). Multitasking refers to activities (e.g. preparing a meal) where the person has to: (a) carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; (b) define the tasks’ targets; (c) and where the person is faced with unexpected problems during the realization of these tasks (Burgess, 2000). However, the cognitive underpinnings of multitasking abilities have never been adequately explored in schizophrenia. Further, only two cognitive models exist in the literature, which are based on student (Logie et al., 2011) and neurological (Burgess et al., 2000) samples. Both of these models suggest three primary constructs: Memory, Planning and Intent. There are, however, several limitations related to the way multitasking abilities were evaluated in these studies. We thus developed a computerized real-life activity task - the Computerized Meeting Preparation Task (CPMT), which was specifically designed to take into account the multitasking nature of certain everyday life activities. Using this task, and based on previous studies (Burgess et al., 2000; Logie et al., 2011), the aim of the present study was to evaluate multitasking abilities in schizophrenia and to do so in a new cognitive model of multitasking that takes into account certain cognitive functions that are not integrated in existing models. Methods: Fifty-seven individuals with schizophrenia and 41 matched healthy controls completed the CMPT. Participants were also evaluated with a battery of cognitive tests. Results: The results suggest that the CMPT possesses good sensitivity and confirmed the three underlying constructs of multitasking (Memory, Planning and Intent), which were found to be underpinned by several cognitive functions and multitasking aspects. Conclusion: Taken together, this new cognitive model and the CMPT could be a good basis for cognitive interventions of multitasking abilities in schizophrenia. Burgess, P.W., 2000. Strategy application disorder: the role of the frontal lobes in human multitasking. Psychol Res 63, 279-288. Logie, R., et al., 2011. Multitasking: multiple, domain-specific cognitive functions in a virtual environment. Mem Cogn 39, 1561-1574. Semkovska, M. et al., 2004. Assessment of executive dysfunction during activities of daily living in schizophrenia. Schizophr Res 69, 289-300. [less ▲]

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See detailEvaluation de l’efficacité de la simulation haute fidélité dans la prise en charge des troubles du rythme cardiaque chez l’enfant: étude pilote
SCHUMACHER, Katharina ULg; Seghaye, Marie-Christine ULg; Baugnon, Thomas et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1),

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See detailExploring limiting factors in the prediction of allogeneic HSCT related mortality: an in-silico machine learning analysis of the acute leukemia working party (ALWP) registry of the EBMT
SHOUVAL, R.; LABOPIN, M.; UNGER, R. et al

in Bone Marrow Transplantation (2015, March), 50

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See detailBenefits of placental transfusion in very preterm infants
Lefebvre, Caroline; MASSON, Véronique ULg; Kalenga, Masendu ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1), 84

Introduction Cord clamping is not a trivial process. Its timing influences the significant physiological changes involved with this nearly universal practice. While the fetal and placental blood volumes ... [more ▼]

Introduction Cord clamping is not a trivial process. Its timing influences the significant physiological changes involved with this nearly universal practice. While the fetal and placental blood volumes add up to 100-120 ml/kg, their distributions differ between preterm and term neonates. The placenta accounts for 50% of the total blood volume in preterm infants and for only 33% in term neonates. Placental transfusion for 60 seconds increases neonatal blood volume by ± 16 ml/kg. In randomized trials, delayed cord clamping in preterm birth is associated with a more stable transitional circulation, a decrease need for inotropic support, and reduce blood transfusions, necrotizing enterocolitis, and intraventricular hemorrhages. Given those benefits, placental transfusion is integrated systematically in our management of preterm births since October 2013. This study aims to confirm expected benefits in a clinical setting. Patients and Methods We conducted a retro-prospective trial in a single tertiary care center. Very preterm infants (VPTi; <32 weeks GA) and VLBWi (BW<1500g) born between April 1st and September 30th 2013 were managed conventionally, with early cord clamping and constitute the control group. These data were collected retrospectively. October 2013 is the month for the new protocols implementation, and infants born this month are not included. Data from VPTi and VLBWi with delayed cord clamping or cord milking were collected prospectively from November 1st 2013 to April 30st 2014. Exclusion criteria were maternal and fetal vital emergencies, Rhesus sensitization, known major congenital abnormalities, tight nuchal cord, meconium teinted liquor, or mother infection by HIV or hepatitis. Results Fifty-two patients are included in the control group. In the second period, 26/XX preterm infants received a placental transfusion, including 6 with a 60 seconds delay in cord clamping and 20 with cord milking. Maternal and neonates’ characteristics were not significantly different. Mean birth weights (BW) were 1208g in the control and 1157g in the placental transfusion groups, with mean gestational age of 28 weeks 4/7 and 28 weeks 6/7, respectively. Mean arterial pressure is significantly increased with placental transfusion (H0 p=0.0006), (H12 p=0.032), (H24 p=0.01). Hemoglobin (H24 p=0,01) and hematocrit (H0 p=0,03), (H12 p=0,05), (H24 p=0,007) are also significantly higher. The number of transfusions per patient transfused (early group 3±2.5 vs. placental transfusion 1±0.4) is significantly lower (p=0.038). No infant with a BW>950g managed with delayed clamping or cord milking did required a transfusion. Conclusion Placental transfusion is associated with a higher blood pressure during the first 24 hours. Placental transfusion also reduces transfusion requirements, with reduction in the number of multi-transfused patients. We found this procedure safe and did not identify short or medium term adverse effects. For preterm infants, the third stage of labor management should evolve toward a more physiological practice, with systematic placental transfusion. [less ▲]

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See detailDairy products & Bone Health: Turning facts and beliefs into clinical practice
Bruyère, Olivier ULg

in Osteoporosis International (2015, March), 26(S1), 383

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See detailPhysical rehabilitation in musculoskeletal conditions: which method?
Bruyère, Olivier ULg

in Osteoporosis International (2015, March), 26(S1), 68

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See detailDesign and implementation of a ‘physical activity day’ for overweight and obese youth
Cloes, Marc ULg; DEWANDRE, Anne-Cécile ULg; LEBRETHON, Marie-Christine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1),

This study aimed to analyze the development and implementation of an adapted physical activity day expected to underline to overweight/obese youth the role of PA and hw they could be more active in their ... [more ▼]

This study aimed to analyze the development and implementation of an adapted physical activity day expected to underline to overweight/obese youth the role of PA and hw they could be more active in their daily life. [less ▲]

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See detailRole of adamalysin proteases in modulations of tumor microenvironment and premetastatic niches
Donati, Kim ULg; Bekaert, Sandrine; Sepult, Christelle ULg et al

in Revue des Maladies Respiratoires (2015, March), 32

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See detailMetabolomic, proteomic and preclinical imaging of patient-derived tumor xenografts for improving treatment of liver metastases patients
Perez Palacios, A; Blomme, A; Boutry, S et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 134

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See detailAzione, testualizzazione, notazione
Dondero, Maria Giulia ULg

in Espressione e contenuto. Rivista on-line dell'AISS Associazione Italiana di Studi Semiotici (2015, February), 18/19

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See detailLes PPP comme nouveau mode de régulation du marché de l'accompagnement des demandeurs d'emploi. A chaque modèle de partenariat son type de stratégie
Remy, Céline ULg

in Cahiers Loyola (2015, February), 1

Cette communication vise à montrer en quoi les partenariats publics-privés (PPP) constituent désormais un nouveau mode de régulation du marché de l’accompagnement des demandeurs d’emploi. Les services ... [more ▼]

Cette communication vise à montrer en quoi les partenariats publics-privés (PPP) constituent désormais un nouveau mode de régulation du marché de l’accompagnement des demandeurs d’emploi. Les services publics de l’emploi (SPE) doivent établir des PPP avec des prestataires de service pour la mise en place de formation à destination des demandeurs d’emploi. La réalisation de trois études de cas au sein des SPE, dont deux en Belgique et une en Suisse, nous permet de mettre en évidence une forte influence du modèle de gestion du PPP sur la collaboration entre les parties-prenantes mais aussi sur les stratégies développées par les prestataires pour surmonter les problèmes liés à la collaboration avec l’Office de l’Emploi et à la mise en place de la prestation de service. [less ▲]

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See detailCastalia — A Mission to a Main Belt Comet
Jones, G. H.; Altwegg, K.; Bertini, I. et al

in LPI (2015, January 01), 1829

Main Belt Comets (MBCs) are a newly identified class of solar system object, having asteroid-like orbits but sometimes exhibiting comet-like behavior. We present the case for a mission to an MBC, to be ... [more ▼]

Main Belt Comets (MBCs) are a newly identified class of solar system object, having asteroid-like orbits but sometimes exhibiting comet-like behavior. We present the case for a mission to an MBC, to be submitted to the European Space Agency. [less ▲]

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See detailMassive stars: privileged sources of cosmic-rays for interstellar astrochemistry
De Becker, Michaël ULg

in Bulletin de la Société Royale des Sciences de Liège (2015, January), 84

Massive stars can be considered as crucial engines for interstellar physics. They are indeed the main providers of UV radiation field, and constitute a substantial source of chemical enrichment. On their ... [more ▼]

Massive stars can be considered as crucial engines for interstellar physics. They are indeed the main providers of UV radiation field, and constitute a substantial source of chemical enrichment. On their evolution time-scale (at most about 10 Myr), they typically stay close to their formation site, i.e. close to molecular clouds very rich in interstellar molecules. These stellar objects have also the property to be involved in particle acceleration processes leading to the production of high energy charged particles (cosmic-rays). After rejection in the interstellar medium, these particles will play a substantial role in processes such as those simulated in various facilities dedicated to experimental astrochemistry. This short contribution intends to put these particles, crucial for astrochemistry, in their adequate astrophysical context. [less ▲]

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See detailPromotion of physical activity among children and adolescents followed for overweight or obesity in
DEWANDRE, Anne-Cécile ULg; HARVENGT, Julie ULg; LAGASSE, Celine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 40

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See detailMono- and Biallelic deletion of neurexin - à propos of 3 cases
Barrea, Christophe ULg; RAMAEKERS, Vincent ULg; Seghaye, Marie-Christine ULg

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 107

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See detailUne gangrène digitale humide traitée de façon conservatrice
Janssen, Aurélie; STERGIOPOULOU, Theodouli ULg; NYAMUGABO MUNYERE NKANA, Kindja ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 64

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See detailCellulite faciale sévère au départ d'une lésion de varicelle - à propos d'un cas
Bourcy, Emilie ULg; Saliba, Mariane ULg; NYAMUGABO MUNYERE NKANA, Kindja ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 113

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See detailRespiratory distress or eating disorder could: it be a vascular ring ?
Solowianiuk, Marie ULg; FARHAT, Nesrine ULg; HOLZKI, Josef ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 98

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See detailPaucisymptomatic presentation of viral myocarditis in children
TSHIMANGA, Prisca ULg; DARON, B.; FARHAT, Nesrine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 98

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See detailAutoimmune thyroid diseases in early childhood three case reports
Guffins, Amandine ULg; HARVENGT, Julie ULg; LUYCKX, F. et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 41

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See detailExercice stress echocardiography in secondary mitral regurgitation : impact of pulmonary hypertension
MAGNE, Julien; PIERARD, Luc ULg; LANCELLOTTI, Patrizio ULg

in Archives of Cardiovascular Diseases (2015, January), 7

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See detailFood provioning influences ranging patterns in northern pigtailed macaques (Macaca leonina)
Huynen, Marie-Claude ULg; Savini, Tommaso ULg; Asensio, Norberto et al

in International Journal of Primatology (2015, January)

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See detailExperimental astrochemistry: from ground-based to space-borne laboratories (Foreword)
De Becker, Michaël ULg; Cottin, Hervé; Fleury-Frenette, Karl ULg et al

in Bulletin de la Société Royale des Sciences de Liège (2015, January), 84(4-6),

The investigation of the origin and evolution of molecules in space environments, either in interstellar or interplanetary conditions, constitutes a topic of high importance in modern space sciences. The ... [more ▼]

The investigation of the origin and evolution of molecules in space environments, either in interstellar or interplanetary conditions, constitutes a topic of high importance in modern space sciences. The presence of diversified and complex molecules motivates astrochemists to explore their formation mechanisms along with the physical conditions ruling these physico-chemical processes. Beside theoretical approaches aiming at simulating these processes, experimental techniques are nowadays frequently applied. Both laboratory and space experiment projects allow to reproduce to some extent the adequate conditions to understand some of these processes. The most recent results based on these techniques, and the prospects for future investigations, including the use of space platforms, were the scientific motivation of this workshop. These proceedings summarize a part of the content of this workshop, including abundant references to the relevant bibliography. [less ▲]

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See detailJAWAC evolving technologies to study sleep disturbance in obese adolescents - a preliminary study
Barrea, Christophe ULg; HARVENGT, Julie ULg; LEBRETHON, Marie-Christine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 107

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See detailGene expression of growth factors and apoptosis regulating proteins in rat myocardium after exposure to endocrine disrupting chemicals : a preliminary study
ROUATBI, Hatem ULg; GERARD, Arlette ULg; Seghaye, Marie-Christine ULg

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 99

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See detailSexually dimorphic effect of gestational exposure to BPA on DNA methylation in the rat placenta
Fudvoye, Julie ULg; Dehan, Pierre ULg; Trooskens, G. et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 37

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See detailDoes gestational diabetes influence foetal organ function ?
Guffins, Amandine ULg; FARHAT, Nesrine ULg; GKIOUGKI, Evangelia ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 99

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See detailComplications de l'appendicite aiguë chez l'enfant : à propos d'un cas
Janssen, Aurélie; NYAMUGABO MUNYERE NKANA, Kindja ULg; STERGIOPOULOU, Theodouli ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 66

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See detailComparison of soil water potential sensors
Degré, Aurore ULg; Cadwell, Todd; van der Ploeg, Martine

in Geophysical Research Abstracts (2015)

Temporal and spatial monitoring of soil water potential and soil water content are necessary for quantifying water flow in the domains of hydrology, soil science and crop production as knowledge of the ... [more ▼]

Temporal and spatial monitoring of soil water potential and soil water content are necessary for quantifying water flow in the domains of hydrology, soil science and crop production as knowledge of the soil water retention curve is important for solving Richards’ equation. Numerous measurement techniques exist nowadays that use various physical properties of the soil-water complex to record changes in soil water content or soil water potential. Laboratory techniques are very useful to determine static properties of the soil water retention curve, and have been used to show the impacts of hysteresis. Yet, other spatiotemporal dynamics resulting from for example growing root systems, biological activity, periodic tillage and their impact on the soil structure cannot satisfactory be quantified in static setups in the laboratory. ). To be able to quantify the influence of soil heterogeneity, and spatiotemporal dynamics on the soil water retention curve, an in situ approach combining soil moisture and soil water potential measurements could provide useful data. Such an in situ approach would require sensors that can measure a representative part of the soil water retention curve. The volumetric soil water content is often measured using time domain reflectometry, and has gained widespread acceptance as a standard electronic means of volumetric water content measurement. To measure the soil water potential, water filled tensiometers are used in most studies. Unfortunately, their range remains limited due to cavitation. Recently, several new sensors for use under in situ conditions have been proposed to cover a wider range of pressure head: Polymer tensiometers, MPS (Decagon) and pF-meter (ecoTech). In this study, we present the principles behind each measurement technique. Then we present the results of a fully controlled experiment where we compared two MPS sensors, two pF-meter sensors and two POT sensors in the same repacked soil. It allows us to discuss advantages and disadvantages of each method. A CS616 volumetric water content probe was installed to compare in situ measured retention curves with laboratory measured retention curves for each method. [less ▲]

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See detailImplémentation d’un cours avec simulation haute fidélité pour la préparation des internes débutant leur formation en pédiatrie et en médecine d’urgence
SCHUMACHER, Katharina ULg; Seghaye, Marie-Christine ULg; Solowianiuk, Marie et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1),

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See detailTracheal diameter in puppies
Rizza, Maïlis ULg; Liotta, Annalisa Pia ULg; Billen, Frédéric ULg et al

in Veterinary Radiology & Ultrasound (2015)

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See detailBaseline characteristics of the Liège Hand Osteoarthritis Cohort (LIHOC)
NEUPREZ, Audrey ULg; Bruyère, Olivier ULg; Dardenne, Nadia ULg et al

in Annals of the Rheumatic Diseases (2015), 74(Supp2), 1346

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See detailHow Many Hippos (HOMHIP): Algorithm for automatic counts of animals with infrared thermal imagery from UAV
Lhoest, Simon ULg; Linchant, Julie ULg; Quevauvillers, Samuel ULg et al

in The International Archives of Photogrammetry, Remote Sensing and Spatial Information Sciences (2015), XL-3/W3

The common hippopotamus (Hippopotamus amphibius L.) is part of the animal species endangered because of multiple human pressures. Monitoring of species for conservation is then essential, and the ... [more ▼]

The common hippopotamus (Hippopotamus amphibius L.) is part of the animal species endangered because of multiple human pressures. Monitoring of species for conservation is then essential, and the development of census protocols has to be chased. UAV technology is considering as one of the new perspectives for wildlife survey. Indeed, this technique has many advantages but its main drawback is the generation of a huge amount of data to handle. This study aims at developing an algorithm for automatic count of hippos, by exploiting thermal infrared aerial images acquired from UAV. This attempt is the first known for automatic detection of this species. Images taken at several flight heights can be used as inputs of the algorithm, ranging from 38 to 155 meters above ground level. A Graphical User Interface has been created in order to facilitate the use of the application. Three categories of animals have been defined following their position in water. The mean error of automatic counts compared with manual delineations is +2.3% and shows that the estimation is unbiased. Those results show great perspectives for the use of the algorithm in populations monitoring after some technical improvements and the elaboration of statistically robust inventories protocols. [less ▲]

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See detailMonkey business: Inter-group differences in the object/food bartering practice in Balinese macaques (Macaca fascicularis) at the Uluwatu Temple, Indonesia
Brotcorne, Fany ULg; Leca, Jean-Baptiste; Gunst, Noelle et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2015), 86

While there is increasing evidence for the social transmission of behavioural innovations and intergroup behavioural variation in a wide range of nonhuman primate taxa, some behavioural domains (e.g ... [more ▼]

While there is increasing evidence for the social transmission of behavioural innovations and intergroup behavioural variation in a wide range of nonhuman primate taxa, some behavioural domains (e.g., tool use) are far more represented than others (e.g., arbitrary social conventions) in the literature. Our study explores the ‘object/food bartering’ activity in the free-ranging long-tailed macaques, Macaca fascicularis, living around the Uluwatu temple, southern Bali (Indonesia). This practice occurs in two steps: after robbing temple visitors of non-edible objects, the monkeys use these objects as tokens, by returning them in exchange for specific food rewards. This spontaneous population-level activity is customary and enduring at Uluwatu, whereas it is very rare or absent at other macaque-tourism sites across the island. During a fourmonth study in 2010 at Uluwatu, we used the all-occurrence sampling technique to record 186 successful events of object-robbing, where 95 (51%) were followed by object/food bartering attempts. In line with the ‘needing-to-learn’ hypothesis, we found that older individuals were significantly more efficient at robbing valuable objects and more successful at exchanging them for food than younger individuals. We also found substantial differences in the frequency and form of the bartering practice (n = 95 events) among the four social groups constituting the Uluwatu population, with two groups (‘Temple’: 60% of the bartering events, ‘Tear’: 34%) being responsible for more frequent bartering events than the two other groups (‘Scarface’: 4%, ‘Nez’: 2%). We investigated the role of group-specific environmental and anthropic influences (food provisioning and degree of human presence) in such intergroup differences. Taken together, these preliminary results suggest that the bartering practice could be a local behavioural tradition in Balinese macaques. [less ▲]

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See detailErratum: Prospective immune profiling in critically ill adults: before, during and after severe sepsis and septic shock.
Layios, N.; GOSSET, Christian ULg; Delierneux, Céline ULg et al

in Critical care (London, England) (2015), 19(1), 300

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See detailMonitoring the pregnancy status of dairy cows using mid-infrared spectra of milk collected from milk recording
Laine, Aurélie ULg; Dale, Laura-Monica ULg; Bel Mabrouk, Hana ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2015), 19(2), 97-124

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See detailOn the relationship between gray matter and behavioral data: lessons learned
Genon, Sarah ULg; Wensing, Tobias; Hoffstaedter, Felix et al

in Proceedings of the Annual Meeting of the Organization of Human Brain Mapping (2015)

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See detailEnergy and nutrient contents of food served and consumed by nursing home residents
Buckinx, Fanny ULg; PAQUOT, Nicolas ULg; ALLEPAERTS, Sophie ULg et al

in The Journal of Nursing Home Research Sciences (2015), 1

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See detailBiomarkers of prognosis and efficacy of treatment in OA
Henrotin, Yves ULg

in BMC Musculoskeletal Disorders (2015), 16(suppl 1),

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See detailAnomaly-free chiral fermion sets and gauge coupling unification
Da Silva Simoes, Catarina ULg

in Journal of Physics: Conference Series (2015)

In this work we search for minimal sets of chiral fermions, with arbitrary quantum numbers, beyond the Standard Model that are anomaly-free and lead to vector-like particles under SU(3) and U(1)_em after ... [more ▼]

In this work we search for minimal sets of chiral fermions, with arbitrary quantum numbers, beyond the Standard Model that are anomaly-free and lead to vector-like particles under SU(3) and U(1)_em after symmetry breaking. We further study which of these anomaly free sets lead to unification of the gauge couplings at energy scales higher that 5.0×10^15 GeV in order to be consistent with proton decay bounds. A similar study is performed in the context of the SU(5) gauge group; for some of the anomaly-free sets found it is possible to obtain unification of the gauge couplings with the extra fermions decoupling at high intermediate scales. [less ▲]

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See detailBaseline Fibulin3 Concentrations Are Associated with Incidence of Clinical Knee OA after 30 Months in Overweight and Obese Women
Runhaar; Sanchez, Christelle ULg; Taralla, Sébastien et al

in Arthritis and Rheumatism (2015), 67(Suppl10),

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See detailOptimization of a new dioxin/PCB clean-up and fractionation procedure for an existing automated system
Calaprice, Chiara ULg; L'Homme, Benjamin; Calvano, Cosima Damiana et al

in Organohalogen Compounds (2015)

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See detailImplementation of geriatric assessment - based recommendations in older patients with cancer : a multicenter prospective study
Baitar, A; Kenis, C; Moor, R et al

in Journal of Geriatric Oncology (2015), 6

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See detailRadiative Origin of Majorana Neutrino Masses
Aristizabal Sierra, Diego ULg

in PoS - Proceedings of Science (2015)

We discuss raditiative-induced neutrino mass mechanisms. We first briefly discuss systematic one-loop level classifications, and then discuss two-loop classification schemes based on a diagrammatic ... [more ▼]

We discuss raditiative-induced neutrino mass mechanisms. We first briefly discuss systematic one-loop level classifications, and then discuss two-loop classification schemes based on a diagrammatic decomposition of the Weinberg operator. We point out that both, the one and two-loop order systematic sorting provides an exhaustive guide for radiative neutrino mass models. [less ▲]

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See detailPrevalence of frailty in nursing home residents according to various diagnostic tools
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Dardenne, Nadia ULg et al

in Journal of Frailty & Aging (2015), 4(S1), 61

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See detailMuscle fatigue resistance and self-perceived fatigue in relation with sarcopenia and quality of life
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Bautmans, I et al

in Journal of Frailty & Aging (2015), 4(S1), 61-62

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See detailL’Anonyme de Londres et les papyrus documentaires grecs de médecine au CEDOPAL
Ricciardetto, Antonio ULg

in Histoire des Sciences Médicales (2015), XLIX(2), 239-245

The present paper proposes an account of my research on human and veterinary medicine in Graeco-Roman and Byzantine Egypt, undertaken since 2008 at the CEDOPAL at the University of Liège. This research ... [more ▼]

The present paper proposes an account of my research on human and veterinary medicine in Graeco-Roman and Byzantine Egypt, undertaken since 2008 at the CEDOPAL at the University of Liège. This research focuses on literary papyri, particularly on the Anonymus Londiniensis (Hermopolis?, 2d half of the Ist century A.D.), the longest known Greek medical papyrus, as well as on documentary fragments, far more numerous than their literary counterparts, of which several categories have been studied in my PhD dissertation defended in Liège in March 2015. [less ▲]

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