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See detailWhen to use locking implants?
Balligand, Marc ULiege

in Proceedings of the 18th ESVOT congress (2016, September)

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See detailLocking implants : polyaxial systems
Balligand, Marc ULiege

in Proceedings of the 18th congress 2016 (2016, September)

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See detailSetting up ex-vivo biomechanics studies
Balligand, Marc ULiege

in Proceedings of the 18th ESVOT congress (2016, September)

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See detailComparative analysis of the respiratory microbiota of healthy dogs and dogs with canine idiopathic pulmonary fibrosis
Roels, Elodie ULiege; Taminiau, Bernard ULiege; Darnis, Elodie ULiege et al

in Journal of Veterinary Internal Medicine (2016, September)

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See detailEVALUATION OF FISH EXPOSURE TO POP-LIKE (ORGANOTIN) COMPOUNDS IN SEPETIBA BAY (RIO DE JANEIRO STATE, BRAZIL) THROUGH HEPATIC TOTAL TIN CONCENTRATIONS
Paiva, TC; Schilithz, PF; Bisi, TL et al

in Organohalogen Compounds (2016, August)

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See detailEVALUATING THE CHEMICAL SAFETY OF EDIBLE INSECTS
Poma, G; Cuykx, M; Amato, E et al

in Organohalogen Compounds (2016, August), 78

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See detailREVISITED SAMPLE PREPARATION APPROACH FOR DIOXIN MEASUREMENTS IN HUMAN SERUM SAMPLES
Calaprice, Chiara ULiege; Focant, Jean-François ULiege

in Organohalogen Compounds (2016, August), 78

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See detailInvolvement of membrane remodelling induced by fatty acids in the regulation of the NLRP3 inflammasome activity in human macrophages
Gianfrancesco, Marco ULiege; Dehairs, Jonas; Bloch, Katarzyna et al

in Diabetologia (2016, August), 59(Supplement 1), 291

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See detailModel-Based Decision Support Algorithm to Guide Fluid Resuscitation
Pironet, Antoine ULiege; Dauby, Pierre ULiege; MORIMONT, Philippe ULiege et al

in IFAC-PapersOnLine (2016, July 26), 49(5), 224-229

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See detailDistinct cerebral metabolic patterns related to high pain sensitivity in episodic or chronic migraine patients and healthy volunteers
D'Ostilio, Kevin ULiege; Lisicki Martinez, Marco ULiege; Schoenen, Jean ULiege et al

in Frontiers in Aging Neuroscience (2016, July)

Introduction Allodynia, i.e. pain evoked by a non-painful stimulus, is prevalent in chronic pain and in migraine where it augments with disease severity and chronicity [1]. Central sensitization is ... [more ▼]

Introduction Allodynia, i.e. pain evoked by a non-painful stimulus, is prevalent in chronic pain and in migraine where it augments with disease severity and chronicity [1]. Central sensitization is thought to be the culprit [2]. It is not known, however, which central areas are involved. The aim of the present study was to evaluate whether brain metabolism in subjects that are more sensitive to pain is different between migraine patients and healthy controls. Subjects and methods Quantitative heat sensory testing on the forehead and 18FDG-PET were performed in 55 subjects: 20 healthy volunteers (HV, 21-59 years, 5M), 21 patients with episodic migraine in the interictal phase (MO, age range: 20-63 years, 5M) and 14 patients with chronic migraine (CM, age range: 22-62 years, 1M). The 3 cohorts were subdivided according to the median heat pain threshold into subgroups with low and high pain thresholds. PET results were compared between these subgroups in each cohort. Data analyses were restricted to areas of the pain/salience matrix. Results There was no significant difference in heat pain thresholds between HV (median: 43.7 °C), MO median: 44.2°C) and CM (median: 43.3°C) (p=0.64). In an SPM-ANOVA, a contrast modelling the potential gradual effect of increased differences in pain sensitivity in relation to disease severity showed significant metabolic changes in bilateral thalamus and midbrain (p < 0.001). Additional analyses revealed that hypometabolic areas in subgroups with a low heat pain threshold differed between HV (anterior cingulate and somatosensory cortices), MO (lower pons and somatosensory cortex) and CM (midbrain and thalamus) (Figure 1). Conclusion Overall migraine patients do not have reduced heat pain thresholds. However, hypometabolic areas related to high thermal pain sensitivity are strictly cortical in HV, but comprise the pons in episodic migraine and are restricted to midbrain and thalamus in chronic migraine. The distinct central correlates of heat pain sensitivity in migraine patients might therefore represent a biomarker of migraine and its chronification. Legend to figure Figure 1. Hypometabolic areas in low pain threshold subgroups in HV (green), MO (orange) and CM (red). p < 0.01 for display purpose. Résumé en Français: Titre: Métabolisme cérébral distinct en relation avec la sensibilité à la douleur entre sujets sains, migraine épisodique et migraine chronique. Les migraineux ont une sensibilité anormale à la douleur. Les mécanismes cérébraux en sont inconnus. Nous avons comparé le métabolisme cérébral chez des sujets sains et chez des migraineux épisodiques ou chroniques et correlé les résultats avec le seuil douloureux. Les aires cérébrales hypométaboliques liées à un seuil douloureux bas diffèrent entre groupes: régions corticales chez les sujets sains, aires corticales et sous-corticales dans la migraine épisodique, régions sous-corticales dans la migraine chronique .Le contrôle central de la douleur semble modifié distinctement dans les formes de migraine, ce qui pourrait en constituer un biomarqueur et avoir des implications thérapeutiques. [less ▲]

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See detailNew antimalarial compounds isolated from Poupartia borbonica, a Mascarene Islands endemic plant
Ledoux, Allison ULiege; Jansen, Olivia ULiege; St-Gelais, Alexis et al

in Planta Medica (2016, July), 82(S01), 1-381

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See detailIn vivo quantification of dopaminergic terminals loss in Parkinson’s Disease rat model: comparison between [18F]FMT and [18F]FDOPA.
Becker, Guillaume ULiege; Bahri, Mohamed Ali ULiege; Michel, Anne et al

in Molecular Imaging & Biology (2016, July), 18(S1), 1744

Objectives: Rat models of Parkinson’s disease (PD), such as unilaterally lesioned rats with 6-hydroxydopamine (6-OHDA), are useful to evaluate novel antiparkinsonian therapies. MicroPET imaging, using L-3 ... [more ▼]

Objectives: Rat models of Parkinson’s disease (PD), such as unilaterally lesioned rats with 6-hydroxydopamine (6-OHDA), are useful to evaluate novel antiparkinsonian therapies. MicroPET imaging, using L-3,4-dihydroxy-6-[18F]-fluoro-phenylalanine ([18F]FDOPA) allows longitudinal evaluations of DA terminals loss. However, chemical structure of [18F]FDOPA leads to suboptimal PET imaging. 18F-fluoro-m-tyrosine ([18F]FMT) is an effective PET tracer to evaluate DA terminals integrity and L-aromatic amino acid decarboxylase (AAAD) metabolic pathway. So far, there are no available quantitative PET studies comparing the two methods in hemiparkinsonian rats. In this study, we compare imaging data provided by [18F]FMT PET and [18F]FDOPA PET in 6-OHDA-lesioned rats. Methods: 10 µg of 6-OHDA were injected into the right medial forebrain bundle (MFB) of male Sprague-Dawley rats (n=8). As control, sham-treated rats (n=8) were injected with vehicle only but otherwise treated identically. Striatal DA presynaptic activity was assessed by dynamic PET with both [18F]FMT and [18F]FDOPA. Structural T2-weighted brain images were acquired on a 9.4T MRI and were used for co-registration. After normalization on a MRI template, kinetic analysis was performed by “Patlak Reference” model, using PMOD software. Six days after the last PET scan, rats were sacrificed, and striatum were rapidly removed for striatal DA and metabolites quantification. Results: Striatal accumulation was observed for both tracers. However, while the administration of [18F]FDOPA required two peripheral inhibitors (benserazide and entacapone), only benserazide is needed with [18F]FMT. As consequence of the 6-OHDA-lesion, significant decrease of both [18F]FMT and [18F]DOPA accumulation was recorded in the striatum ipsilateral to the lesion. Lesioned rats had dramatically reduced uptake constant Ki in the ipsilateral striatum compared to the contralateral striatum (p<0.001 for [18F]FMT and p<0.05 for [18F]DOPA) and to the ipsilateral striatum of sham-treated rats (p<0.001 for both tracers). The DA content in the ipsilateral striatum was significantly lower (p<0.001) than in the contralateral striatum in the 6-OHDA-injected group, whereas such difference was not measured with the sham group. This indicate that [18F]FMT PET is as effective as [18F]DOPA PET to quantify loss of DA presynaptic function in unilaterally 6-OHDA lesioned rats. Conclusions: Our results are in agreement with data reporting correlation between these two tracers in a Non-human primate model of PD. The sensitivity of the data quantification obtained in this study, confirms the interest to pursue longitudinal investigations with [18F]FMT to monitor dopaminergic dysfunction in a more progressive preclinical model of PD. [less ▲]

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See detailThe shadow position sensors (SPS) formation flying metrology subsystem for the ESA PROBA-3 mission: Present status and future developments
Focardi, Mauro; Thizy, Cédric ULiege; Renotte, Etienne ULiege

in Proceedings of SPIE (2016, June)

PROBA-3 [1] [2] is a Mission of the European Space Agency (ESA) composed of two formation-flying satellites, planned for their joint launch by the end of 2018. Its main purposes have a dual nature ... [more ▼]

PROBA-3 [1] [2] is a Mission of the European Space Agency (ESA) composed of two formation-flying satellites, planned for their joint launch by the end of 2018. Its main purposes have a dual nature: scientific and technological. In particular, it is designed to observe and study the inner part of the visible solar corona, thanks to a dedicated coronagraph called ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun), and to demonstrate the in-orbit formation flying (FF) and attitude control capability of its two satellites. The Coronagraph payload on-board PROBA-3 consists of the following parts: the Coronagraph Instrument (CI) with the Shadow Position Sensor (SPS) on the Coronagraph Spacecraft (CSC), the Occulter Position Sensor (OPSE) [3] [4] and the External Occulting (EO) disk on the Occulter Spacecraft (OSC). The SPS subsystem [5] is one of the main metrological devices of the Mission, adopted to control and to maintain the relative (i.e. between the two satellites) and absolute (i.e. with respect to the Sun) FF attitude. It is composed of eight micro arrays of silicon photomultipliers (SiPMs) [6] that shall be able to measure, with the required sensitivity and dynamic range as asked by ESA, the penumbral light intensity on the Coronagraph entrance pupil. With the present paper we describe the testing activities on the SPS breadboard (BB) and Development Model (DM) as well as the present status and future developments of this PROBA-3 metrological subsystem. [less ▲]

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See detailPreliminary evaluation of the diffraction behind the PROBA 3/ASPIICS optimized occulter
Baccani, Cristian; Thizy, Cédric ULiege; Renotte, Etienne ULiege

in Proceedings of SPIE (2016, June)

ROBA-3 is a technological mission of the European Space Agency (ESA), devoted to the in-orbit demon- stration of formation flying (FF) techniques and technologies. ASPIICS is an externally occulted ... [more ▼]

ROBA-3 is a technological mission of the European Space Agency (ESA), devoted to the in-orbit demon- stration of formation flying (FF) techniques and technologies. ASPIICS is an externally occulted coronagraph approved by ESA as payload in the framework of the PROBA-3 mission and is currently in its C/D phase. FF offers a solution to investigate the solar corona close the solar limb using a two-component space system: The external occulter on one spacecraft and the optical instrument on the other, separated by a large distance and kept in strict alignment. ASPIICS is characterized by an inter-satellite distance of â1/4144 m and an external occulter diameter of 1.42 m. The stray light due to the diffraction by the external occulter edge is always the most critical offender to a coronagraph performance: The designer work is focused on reducing the stray light and carefully evaluating the residuals. In order to match this goal, external occulters are usually characterized by an optimized shape along the optical axis. Part of the stray light evaluation process is based on the diffraction calculation with the optimized occulter and with the whole solar disk as a source. We used the field tracing software VirtualLabTM Fusion by Wyrowski Photonics [1] to simulate the diffraction. As a first approach and in order to evaluate the software, we simulated linear occulters, through as portions of the flight occulter, in order to make a direct comparison with the Phase-A measurements [2]. [less ▲]

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See detailALERBLOT: Interest of 2D Immunoblot for the diagnosis of allergy to wheat
BERTHOLET, Catherine ULiege; GADISSEUR, Romy ULiege; quinting, birgit et al

in Allergy (2016, June), 71

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See detailVUV Optical Ground System Equipment and its application to the ICON FUV flight grating characterization and selection
Blain, Pascal ULiege; Desselle, Richard ULiege; Domken, Isabelle ULiege et al

in Advances in Optical and Mechanical Technologies for Telescopes and Instrumentation (2016, June)

ICON FUV is a two channel spectrographic imager that measures intensity and spatial distribution of oxygen (135.6 nm) and molecular nitrogen (157 nm) of the ionosphere. As those wavelengths are strongly ... [more ▼]

ICON FUV is a two channel spectrographic imager that measures intensity and spatial distribution of oxygen (135.6 nm) and molecular nitrogen (157 nm) of the ionosphere. As those wavelengths are strongly absorbed by the atmosphere, the optical elements of the system have to be tested inside vacuum chambers. Prior to the instrument alignment and calibration, two 3600 gr/mm gratings were characterized. The primary focus is the measurement of the diffraction efficiencies; while the second objective is to select the best grating and to define which is the flight and the spare. A dedicated setup has been developed to assess the grating optical performances under vacuum. A 1 cm diameter collimated beam is generated using an off-axis parabola and a UV source at its focal point. The grating is placed at the center of two rotation stages collinearly aligned. One detector is placed on a rotating arm, deported from its rotation center. A PMT detector records diffracted light intensity with respect to its angular position and its wavelength. Angular incidence on the grating is tuned with the help of the second rotation stage. The grating efficiency homogeneity and scattering properties are measured through a Y-X scan. [less ▲]

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See detailDe Reinach à Levinas : Hering et le réalisme phénoménologique
Boccaccini, Federico ULiege

in Revue de théologie et de Philosophie (2016, June)

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See detailInstauration d'un trajet de réintégration multidisciplinaire au sein de l'Assurance Maladie belge : ombres et lumière
Mairiaux, Philippe ULiege

in Archives des Maladies Professionnelles et de l'Environnement (2016, June), 77(3), 363

Le modèle dit de Sherbrooke développé par P. Loisel au Québec constitue le fondement des recommandations internationales en matière de programmes de retour au travail pour les travailleurs souffrant de ... [more ▼]

Le modèle dit de Sherbrooke développé par P. Loisel au Québec constitue le fondement des recommandations internationales en matière de programmes de retour au travail pour les travailleurs souffrant de lombalgie. Ce modèle a inspiré les recommandations belges et françaises (HAS 2013) en la matière. De nombreuses études explorent maintenant la possibilité d’une intervention précoce en milieu de travail – un des axes essentiels du modèle de Sherbrooke - dans d’autres problématiques de santé que la lombalgie, et notamment en cas de décompensation psychique. La combinaison d’une telle intervention avec les approches propres aux milieux de soin représente cependant un réel défi. Le programme de prévention secondaire de la lombalgie initié en Belgique en 2004 dans le cadre de l’assurance maladies professionnelles permet d’illustrer quelques-unes des difficultés à surmonter : information du public-cible (tout travailleur exposé à la manutention de charges et/ou aux vibrations corps-entier) et des médecins traitants concernés, mise en place d’une collaboration, jusque-là inexistante, entre médecins de revalidation et médecins du travail, sensibilisation des employeurs. Même la collaboration entre médecins se heurte à de sérieuses barrières. Elle implique en effet un dialogue et une relation de confiance entre le médecin traitant qui considère prioritairement la protection de son patient, le médecin du travail qui a à juger l’aptitude d’un travailleur pour une activité de travail définie et un médecin-conseil de la sécurité sociale dont la fonction centrale était encore récemment le contrôle du bien-fondé de l’arrêt de travail afin de préserver l’équilibre financier du système. La prévention de la désinsertion professionnelle devrait idéalement constituer un objectif commun à ces trois métiers médicaux mais il s’agit à l’évidence d’un chantier de longue haleine. La décision du gouvernement belge d’instaurer un trajet de réintégration multidisciplinaire au sein de l'Assurance Maladie pour tout assuré en arrêt-maladie depuis 3 mois a révélé, avant même sa mise en application prévue en 2016, les enjeux sous-jacents à un tel projet. Les négociations avec les partenaires sociaux ont abordé plusieurs questions. Veut-on promouvoir plus d’équité sociale, ou simplement limiter l’augmentation alarmante des dépenses d’invalidité ? L’entrée de l’assuré dans le trajet proposé va-t-elle se faire sur base volontaire, ou faut-il prévoir une sanction financière en cas de refus ? A quel médecin confier la direction du trajet ? Quelle place réserver au médecin du travail, et au médecin traitant ? Faut-il prévoir une responsabilisation financière de l’entreprise ou faire confiance à la bonne volonté des employeurs ? [less ▲]

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See detailEffect of chondroitin sulfate on soluble biomarkers of osteoarthritis: how to analyze and interpret the results from an open-label trial in unilateral knee osteoarthritis patients
Möller, I; Gharbi, Myriam; Martinez, H et al

in Annals of the Rheumatic Diseases (2016, June), 75(Suppl 2), 1167

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See detailAlignment and calibration of the ICON-FUV instrument: Development of a vacuum UV facility
Loicq, Jerôme ULiege; Blain, Pascal ULiege; Kintziger, Christian ULiege et al

in Proceedings of SPIE (2016, June)

The optical calibration of the ICON-FUV instrument requires designing specific ground support equipment (GSE). The ICON-FUV instrument is a spectrographic imager that operates on two specific wavelengths ... [more ▼]

The optical calibration of the ICON-FUV instrument requires designing specific ground support equipment (GSE). The ICON-FUV instrument is a spectrographic imager that operates on two specific wavelengths in the UV (135.6 nm and 157 nm). All the operations have to be performed under vacuum UV light. The optical setup is based on a VUV monochromator coupled with a collimator that illuminates the FUV entrance slit. The instrument is placed on a manipulator providing fields pointing. Image quality and spectral properties can be then characterized for each field. OGSE, MGSE, optical calibration plan and vacuum alignment of the instrument are described. [less ▲]

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See detailOptical design and optical properties of a VUV spectrographic imager for ICON mission
Loicq, Jerôme ULiege; Kintziger, Christian ULiege; Mazzoli, Alexandra ULiege et al

in Proceedings of SPIE (2016, June)

In the frame of the ICON (Ionospheric Connection Explorer) mission of NASA led by UC Berkeley, CSL and SSL Berkeley have designed in cooperation a new Far UV spectro-imager. The instrument is based on a ... [more ▼]

In the frame of the ICON (Ionospheric Connection Explorer) mission of NASA led by UC Berkeley, CSL and SSL Berkeley have designed in cooperation a new Far UV spectro-imager. The instrument is based on a Czerny-Turner spectrograph coupled with two back imagers. The whole field of view covers [± 12° vertical, ± 9° horizontal]. The instrument is surmounted by a rotating mirror to adjust the horizontal field of view pointing by ± 30°. To meet the scientific imaging and spectral requirements the instrument has been optimized. The optimization philosophy and related analysis are presented in the present paper. PSF, distortion map and spectral properties are described. A tolerance study and alignment cases were performed to prove the instrument can be built and aligned. Finally straylight and out of band properties are discussed. [less ▲]

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See detailRecent achievements on ASPIICS, an externally occulted coronagraph for PROBA-3.
Renotte, Etienne ULiege; Denis, François ULiege; Desselle, Richard ULiege et al

in Proceedings of SPIE (2016, June)

This paper presents the current status of ASPIICS, a solar coronagraph that is the primary payload of ESA’s formation flying in-orbit demonstration mission PROBA-3. The “sonic region” of the Sun corona ... [more ▼]

This paper presents the current status of ASPIICS, a solar coronagraph that is the primary payload of ESA’s formation flying in-orbit demonstration mission PROBA-3. The “sonic region” of the Sun corona remains extremely difficult to observe with spatial resolution and sensitivity sufficient to understand the fine scale phenomena that govern the quiescent solar corona, as well as phenomena that lead to coronal mass ejections (CMEs), which influence space weather. Improvement on this front requires eclipse-like conditions over long observation times. The space-borne coronagraphs flown so far provided a continuous coverage of the external parts of the corona but their over-occulting system did not permit to analyse the part of the white-light corona where the main coronal mass is concentrated. The PROBA-3 Coronagraph System, also known as ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun) is designed as a classical externally occulted Lyot coronagraph but it takes advantage of the opportunity to place the external occulter on a companion spacecraft, about 150m apart, to perform high resolution imaging of the inner corona of the Sun as close as ~1.1 solar radii. The images will be tiled and compressed on board in an FPGA before being down-linked to ground for scientific analyses. ASPIICS is built by a large European consortium including about 20 partners from 7 countries under the auspices of the European Space Agency. This paper is reviewing the recent development status of the ASPIICS instrument as it is approaching CDR. [less ▲]

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See detailThe satellite formation flying in lab: PROBA-3/ASPIICS metrology
Capobianco, G; Thizy, Cédric ULiege; Renotte, Etienne ULiege

in Proceedings of SPIE (2016, June)

Formation flying is one of the most promising techniques for the future of astronomy and astrophysics from the space. The capabilities of the rockets strongly affect the dimensions and the weights of ... [more ▼]

Formation flying is one of the most promising techniques for the future of astronomy and astrophysics from the space. The capabilities of the rockets strongly affect the dimensions and the weights of telescopes and instrumentation to be launched. Telescopes composed by several smallest satellites in formation flying, could be the key for build big space telescopes. With this aim, the ESA PROBA-3 mission will demonstrate the capabilities of this technology, maintaining two satellites aligned within 1 mm (longitudinal) when the nominal distance between the two is of around 144m. The scientific objective of the mission is the observation of the solar corona down to 1.08 solar radii. The Coronagraph Spacecraft (CSC) will observe the Sun, when the second spacecraft, the Occulter Spacecraft (OSC) will work as an external occulter, eclipsing to the CSC the sun disk. The finest metrology sub-systems, the Shadow Position Sensors (SPS) and the Occulter Position Sensor Emitters (OPSE) identifying respectively the CSC-Sun axis and the formation flying (i.e., CSC-OSC) axis will be considered here. In particular, this paper is dedicated to the test-bed for the characterization, the performance analysis and the algorithms capabilities analysis of the both the metrology subsystems. The test-bed is able to simulate the different flight conditions of the two spacecraft and will give the opportunity to check the response of the subsystems in the conditions as close as possible to the flight ones. [less ▲]

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See detailCharacterization of the ASPIICS/OPSE metrology sub-system and PSF centroiding procedure.
Lorregia, D; Thizy, Cédric ULiege; Renotte, Etienne ULiege

in Proceedings of SPIE (2016, June)

Metrology in diluted systems for space applications is one of the most important technology research fields that in recent years have raised increasing interest. Many applications of astronomical ... [more ▼]

Metrology in diluted systems for space applications is one of the most important technology research fields that in recent years have raised increasing interest. Many applications of astronomical observation techniques, as coronography and interferometry get great benefit when moved in space and the employment of diluted systems represents a milestone to step-over in astronomical research. In this work, we present the Optical Position Sensors Emitter (OPSE) metrological sub-system on-board of the PROBA3. PROBA3 is an ESA technology mission that will test in-orbit many metrology techniques for the maintenance of a Formation Flying with two satellites, in this case an occulter and a main satellite housing a coronagraph named ASPIICS, kept at an average inter-distance of 144m. The scientific task is the observation of the Sun’s Corona at high spatial and temporal resolution down to 1.08R⊙. The OPSE will monitor the relative position of the two satellites and consists of 3 emitters positioned on the rear surface of the occulter, that will be observed by the coronagraph itself. A Centre of Gravity (CoG) algorithm is used to monitor the emitter’s PSF at the focal plane of the Coronagraph retrieving the Occulter position with respect to the main spacecraft. The 3 location target accuracy is 300m for lateral movement and 21cm for longitudinal movements. A description of the characterization tests on the OPSE LED sources, and of the design for a laboratory set-up for on ground testing is given with a preliminary assessment of the performances expected from the OPSE images centroiding algorithm. [less ▲]

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See detail188Re and 68Ga radiolabeled Starch-Based Microparticles as potential theranostic radiopharmaceutical for Hepatocellular Carcinoma
Verger, Elise ULiege; Drion, Pierre ULiege; MEFFRE, Geneviève ULiege et al

in Journal of Nuclear Medicine (The) (2016, May 01), 57(suppl. 2),

The SBMP as a unique vector is a promising theranostic agent for the SIRT of HCC.

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See detailRoof Frames in the Buit Heritage of Brussels (Belgium): The contribution of dendrochronology and written sources
Weitz, Armelle ULiege; Charruadas, Paulo; Fraiture, Pascale et al

in Tree Rings in Archaeology, Climatology and Ecology (2016, May), 14

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See detailMicroparticules à base d’amidon radiomarquées au 188Re et 68Ga comme agent théranostique pour la radiothérapie interne sélective du carcinome hépatocellulaire
Verger, Elise ULiege; Drion, Pierre ULiege; MEFFRE, Geneviève ULiege et al

in Médecine Nucléaire (2016, May), 40(3), 182

Les microparticules SBMP, en étant capable d'être radiomarquées rapidement, de manière reproductible, sous forme de kits prêt-à-l‘emploi, par du 188Re et du 68Ga, se révèlent être un outil théranostique ... [more ▼]

Les microparticules SBMP, en étant capable d'être radiomarquées rapidement, de manière reproductible, sous forme de kits prêt-à-l‘emploi, par du 188Re et du 68Ga, se révèlent être un outil théranostique prometteur pour le traitement du carcinome hépatocellulaire. [less ▲]

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See detailModelling Urban Expansion: A Multiple Urban-Densities Approach
El Saeid Mustafa, Ahmed Mohamed ULiege; Saadi, Ismaïl ULiege; Cools, Mario ULiege et al

in Proceedings of GEOProcessing 2016 (2016, April 24)

Most existing spatio-temporal urban expansion models consider urban land-use as a binary process, through the identification of urban versus non-urban areas. The main aim of this study is to analyze and ... [more ▼]

Most existing spatio-temporal urban expansion models consider urban land-use as a binary process, through the identification of urban versus non-urban areas. The main aim of this study is to analyze and model the expansion of multiple urban densities in Wallonia, Belgium. To this end, this study employs a multinomial logistic regression model that enables to visualize the consequence of different urban densities expansion. Cadastral datasets of years 2000 and 2010 are used to set four urban classes (non-urban, low-density, medium-density and high-density urban). Besides, several socio-economic, geographic and political driving forces dealing with urban development were operationalized to create maps of urban expansion probability for each urban density class. These probability maps are then utilized to predict future urban expansions for years 2020 and 2030. The model is validated using relative operating characteristic method for different urban classes. Our results suggest that different urban densities expansions are mainly linked to zoning status, neighboring areas that are urban and accessibility. Most importantly, this study highlights that the contribution of different driving forces to urban expansion process varies along with urban density. [less ▲]

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See detailDesign and Modelization of a convex grating for the hyperspectral imager Chandrayaan 2: spectral optimization based on free form profile
Sabushimike, Bernard ULiege

in International Journal of Latest Research in Science and Technology (2016, April 20), 5(2), 69-74

For hyperspectral imaging, diffraction gratings based spectrometers exhibit high spectral resolution and optical performance. Among those spectrometers, the Offner type (which consists of an entrance slit ... [more ▼]

For hyperspectral imaging, diffraction gratings based spectrometers exhibit high spectral resolution and optical performance. Among those spectrometers, the Offner type (which consists of an entrance slit, two concave mirrors and convex grating) offers a lot of advantages. In this paper, we propose the design and modelization of a convex grating which covers a spectral band ranging from 0.7 μm to 5 μm with a minimum diffraction efficiency of 20% at 8 00 nm, 50% at 3000 nm and 25% at 5000 nm. For a so wide band, a grating with a single blaze cannot satisfy these requirements. Wewill therefore propose an approach of multi-blaze grating which is subdivided intodifferent sections each with its own blaze angle. Meanwhile, we perform the diffraction efficiency prediction using the scalar and rigorous theories to prove the compliance of this design with the technical specifications. The rigorous theory will also allow us to study the polarization sensitivity of this grating and the calculation of the diffraction efficiency of a grating with a profile degraded by manufacturing errors to assess the impact on the diffraction efficiency and the sensitivity to polarization. [less ▲]

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See detailUsing NDACC column measurements of carbonyl sulfide to estimate its sources and sinks
Wang; Marshall, J; Palm, M et al

in Geophysical Research Abstracts (2016, April 19), 18

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See detailAbel inversion method for cometary atmospheres.
Hubert, Benoît ULiege; Opitom, Cyrielle ULiege; Hutsemekers, Damien ULiege et al

in Geophysical Research Abstracts (2016, April 01), 18

Remote observation of cometary atmospheres produces a measurement of the cometary emissions integrated along the line of sight joining the observing instrument and the gas of the coma. This integration is ... [more ▼]

Remote observation of cometary atmospheres produces a measurement of the cometary emissions integrated along the line of sight joining the observing instrument and the gas of the coma. This integration is the so-called Abel transform of the local emission rate. We develop a method specifically adapted to the inversion of the Abel transform of cometary emissions, that retrieves the radial profile of the emission rate of any unabsorbed emission, under the hypothesis of spherical symmetry of the coma. The method uses weighted least squares fitting and analytical results. A Tikhonov regularization technique is applied to reduce the possible effects of noise and ill-conditioning, and standard error propagation techniques are implemented. Several theoretical tests of the inversion techniques are carried out to show its validity and robustness, and show that the method is only weakly dependent on any constant offset added to the data, which reduces the dependence of the retrieved emission rate on the background subtraction. We apply the method to observations of three different comets observed using the TRAPPIST instrument: 103P/ Hartley 2, F6/ Lemmon and A1/ Siding spring. We show that the method retrieves realistic emission rates, and that characteristic lengths and production rates can be derived from the emission rate for both CN and C2 molecules. We show that the emission rate derived from the observed flux of CN emission at 387 nm and from the C2 emission at 514.1 nm of comet Siding Spring both present an easily-identifiable shoulder that corresponds to the separation between pre- and post-outburst gas. As a general result, we show that diagnosing properties and features of the coma using the emission rate is easier than directly using the observed flux. We also determine the parameters of a Haser model fitting the inverted data and fitting the line-of-sight integrated observation, for which we provide the exact analytical expression of the line-of-sight integration of the Haser model. [less ▲]

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See detailOsteoarthritic sclerotic subchondral osteoblasts secreted elevated concentration of fibulin-3 fragments in vitro
Sanchez, Christelle ULiege; Lambert, Cécile ULiege; Comblain, Fanny ULiege et al

in Osteoarthritis and Cartilage (2016, April), 24(suppl 1), 83

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See detailReview of soluble biomarkers of osteoarthritis: lessons from animal model
Legrand, Catherine ULiege; Lambert, Cécile ULiege; Comblain, Fanny ULiege et al

in Osteoarthritis and Cartilage (2016, April), 24(suppl 1), 88

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See detailIs isokinetic exercise dangerous for the heart?
Le Goff, Caroline ULiege; Kaux, Jean-François ULiege; Cavalier, Etienne ULiege et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(suppl. 1 No. 2), 457

INTRODUCTION: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in ... [more ▼]

INTRODUCTION: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in order to perform these very intensive exercises; otherwise an acute myocardial dysfunction could theoretically appear in predisposed patients. PURPOSE: Our study aimed to observe the cardiovascular impact (by biological point of view) of maximal intense isokinetic eccentric and concentric protocols performed by a population of sedentary young men. METHOD: Resting (T0) and post-exercise (just after (T1), 3 hours (T2) and 24 hours after the exercise (T3)) blood samples were taken in 2 populations of young sedentary men: 12 subjects (22.5±1.15 yo) for the eccentric protocol and 18 subjects (22.4±2.6 yo) for the concentric protocol. These subjects performed an intense maximal isokinetic exercise of the quadriceps muscles involving 30 knee flexions–extensions for each leg. We evaluated markers of cardiovascular risk (highly sensitive troponin T (hs-TnT), N-Terminal Brain natriuretic peptide (NT-proBNP), myoglobin (MYO)), of inflammation (highly sensitive C-reactive protein (hsCRP)), muscle damage (creatine kinase (CK)) and of oxidative stress (myeloperoxidase (MPO), lipidic peroxides (POXL), reduced (GSH) and oxidised glutathione (GSSG)). Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: All the physiological parameters measured presented statistically significant changes. For the eccentric exercise, no significant modification in cardiac (NT-proBNP, hs-TNT) and inflammation (hsCRP) biomarkers was observed. However, a significant increase for CK (T3), MYO (T2), MPO (T1), POXL (T1), GSSG (T3) and ratio GSH/GSSG (T2-T3) was shown. For the concentric exercise, the results showed significant increases for the CK (T1-T2-T3), MYO (T1-T2), GSH/GSSG (T1). Evolutionary trends were also observed for the following biomarkers: NT-proBNP (T1-T2-T3), MPO (T2), and GSSG (T4). DISCUSSION and CONCLUSIONS: No modification in cardiac biomarkers was observed after the maximal eccentric isokinetic exercise but some variations can be observed for these biomarkers after the concentric exercise. However, these changes do not exceed the reference values in healthy subjects. We were thus able to prove that the exercise could be performed without any risk to cardiac function in young sedentary subjects. Nevertheless, a significant level of oxidative stress was induced by both exercises. [less ▲]

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See detailEffectiveness of High Intensity Radial Shock Wave Therapy in The Treatment of Chronic Plantar Fasciitis
Demoulin, Christophe ULiege; Vanderthommen, Marc ULiege; Fromm, Aurélien et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(Suppl. 1 No. 2), 733

Introduction: Literature is scarce concerning the effectiveness of high dose radial extracorporeal shock wave therapy (ESWT). Therefore, the aim of this study was to investigate its effectiveness on pain ... [more ▼]

Introduction: Literature is scarce concerning the effectiveness of high dose radial extracorporeal shock wave therapy (ESWT). Therefore, the aim of this study was to investigate its effectiveness on pain, function and pressure pain threshold in patients with chronicplantar fasciitis (PF). Materials and Methods: Patients with a diagnosis of chronic (pain lasting for more than 3 months) uni- or bilateral PF with a history of failed conservative treatment were included. After a 6-week control period during which no treatment occurred, a 2-week treatment period followed by a three weeks of rest (cicatrization phase) was provided. The treatment period consisted of three radial ESWT sessions (2000 impulses of 10 Hz frequency per session with an energy flux density of 0,275mJ/mm2) separated by a one-weekinterval. Patient assessments (pain intensity, foot function and pressure pain threshold (PPT) at the site of maximum local tenderness disability) were conducted at baseline, after the 6-week control phase (pre-treatment) and at the end of the cicatrization phase (post-treatment). Results: Thirty patients (19 women (63.3%)) with chronic PF and a mean age of 51.9±11 years were included in the present study. No drop-out occurred throughout the study period. No changes were observed at the pre-treatment assessment session except for pain intensity which decreased slightly but significantly (P<0.05). At the post-treatment session, highly significant (P<0.001) and clinically meaningful changes occurred for pain intensity (-34%), foot function score (-60%) and PPT (+68%). Conclusions: The present study suggests that high dose radial ESWT is a feasible and effective way to quickly and significantly decrease pain and disability in most patients with chronic PF. [less ▲]

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See detailTen years of Denosumab (DMAB) treatment in postmenopausal women with osteoporosis. Results from the FREEDOM Extension trial.
Bone, H.G.; Brandi, M.L.; Brown, J.P. et al

in Osteoporosis International (2016, April), 27(Supplement 1), 135-136

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See detailPrevalence of frailty among nursing home, according to different operational definitions.
Buckinx, Fanny ULiege; Reginster, Jean-Yves ULiege; GILLAIN, Sophie ULiege et al

in Osteoporosis International (2016, April), 27(Supplement 1), 216-217

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See detailIdentification of a Spectrum of Therapeutic Targets of a New Treatment for Osteoarthritis Composed by Curcuminoids Extract, Hydrolyzed Collagen and Green Tea Extract
Comblain, Fanny ULiege; Dubuc, Jean-Emile; Lambert, Cécile ULiege et al

in Osteoarthritis and Cartilage (2016, April), 24(Supp 1), 353

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See detailA randomized double-blind study of Denosumab (DMAB) compared with Zoledronic acid (ZOL) in postmenopausal women with osteoporosis previously treated with oral bisphosphonates
Miller, P.; Pannacciulli, N.; Brown, J.P. et al

in Osteoporosis International (2016, April), 27(SUPPLEMENT1), 42

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See detailEfficacy and safety of glucosamine sulfate in the management of osteoarthritis: Evidence from real-life setting trials and surveys.
Reginster, Jean-Yves ULiege

in Osteoporosis International (2016, April), 27(supplement 1), 65

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See detailEfficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys.
Rannou, F.; Maheu; Reginster, Jean-Yves ULiege

in Osteoporosis International (2016, April), 27(supplement 1), 66

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See detailrelationship between total hip BMD T-score and incidence of nonvertebral fracture with up to 10 years of Denosumab (DMAB) treatment
Ferrari, S.; ADAMI, S.; Brown, J.P. et al

in Osteoporosis International (2016, April), 27(Supplement 1), 49-50

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See detailThe future prevalence of sarcopenia in Europe
Ethgen, Olivier ULiege; Tchoconte, C.; Beaudart, Charlotte ULiege et al

in Osteoporosis International (2016, April), 27(Supplement 1), 53-54

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See detailPrevalence of concomitant bone and muscle wasting in patients from the SarcoPhAge study.
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Reginster, Jean-Yves ULiege et al

in Osteoporosis International (2016, April), 27(supplement 1), 129

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See detailPrevalence of sarcopenia in a population of nursing home residents according to their frailty status: results of the Senior cohort
Buckinx, Fanny ULiege; Reginster, Jean-Yves ULiege; Beaudart, Charlotte ULiege et al

in Osteoporosis International (2016, April), 27(supplement 1), 55-56

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See detailPhysical and muscle performances among elderly nursing home residents.
Buckinx, Fanny ULiege; Reginster, Jean-Yves ULiege; Croisier, Jean-Louis ULiege et al

in Osteoporosis International (2016, April), 27(Supplement 1), 217

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See detailEnglish translation and cross-cultural adaptation of the SarQuoL® questionnaire.
Beaudart, Charlotte ULiege; Edwards, M.; Dennison, E.M. et al

in Osteoporosis International (2016, April), 27(Supplement 1), 221-222

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See detailAge-standardized quality of life after hip or knee arthoplasty.
Neuprez, Audrey ULiege; KURTH, William ULiege; THIRION, Thierry ULiege et al

in Osteoporosis International (2016, April), 27(Supplement 1), 541-542

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See detailBrain-derived neurotrophic factor (BDNF) in normal healthy and hemodialyzed populations.
CAVALIER, Etienne ULiege; CARLISI, Ignazia ULiege; KOVACS, Stéphanie ULiege et al

in Osteoporosis International (2016, April), 27(Supplement 1), 512

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See detailGood prognosis factors after a platelet rich plasma (PRP) injection for tendinopathies ?
Kaux, Jean-François ULiege; Sancerne, Audrey; Libertiaux, Vincent ULiege

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(suppl. 1 No. 2), 251

Introduction : Platelet-rich plasma injections are a recent treatment for chronic tendinopathies. However, this theraeutic remains controversed in litterature. Up to now, there is no prognosis factors ... [more ▼]

Introduction : Platelet-rich plasma injections are a recent treatment for chronic tendinopathies. However, this theraeutic remains controversed in litterature. Up to now, there is no prognosis factors identified to predict a good evolution after injection of PRP. Purpose: The aims of this study were to evaluate the effect of PRP injection followed by a standardized reeducation protocol among patients suffering from different tendinopathies and to determine the good prognosis factors, if any. Methods : 51 patients suffering from different tendinopathies and refractory to conventional physiotherapy were treated with a PRP injection. Prior to the injection, a blood sample was drawn and some biological parameters (glycemia, cholesterol level, …). A pain assessment was then made using a visual analog scale (VAS) and a pressure algometer. The same assessment was carried out after 6 weeks and 12 weeks when possible. Results : There is an overall significant improvement VAS score at the end of the 12 weeks follow- up. However, no correlation was found between the evolution of the clinical scores and the biological parameters measured. Discussion and Conclusions : A PRP injection followed by a program of eccentric rehabilitation positively affects the algo-functional scores of patients with tendinopathie who were refractory to conventional physiotherapy, whatever their initial biological parameters. [less ▲]

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See detailExploring the effect of a second closely-timed infiltration of platelet-rich plasma to treat proximal patellar tendinopathies
Kaux, Jean-François ULiege; CROISIER, Jean-Louis ULiege; FORTHOMME, Bénédicte ULiege et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 54(Suppl. 1 No. 2), 199

Intorduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to ... [more ▼]

Intorduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of 2 or 3 successive infiltrations. Purpose: The aim of this study was to evaluate whether 2 infiltrations of PRP proves more effective than a single treatment. Methods: Twenty patients suffering from chronic jumper’s knee were enrolled into the study and split into two randomized groups (1 or 2 infiltrations of PRP, respectively). The 3-month follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. After 1 year, subjects were contacted to define their functional evolution. Results: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. Discussion and Conclusion: The comparison between 1 or 2 infiltrations of PRP did not reveal any difference between the 2 groups at short to mid term. A second closely-timed infiltration of PRP to treat jumper’s knees is not necessary to improve the efficacy of this treatment in the short term. A second infiltration should perhaps be envisaged later, but this remains to be demonstrated. [less ▲]

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See detailMise au point d’une nouvelle méthode de diagnostic des allergènes du froment par Western blot 2D
BERTHOLET, Catherine ULiege; GADISSEUR, Romy ULiege; Quinting, Birgit

in Revue Française d'Allergologie (2016, April), 56(3), 284

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See detailMuscular and functional tridimensional analysis after hamstring strain
Paulus, Julien ULiege; DELVAUX, François ULiege; Schwartz, Cédric ULiege et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(2), 263

Introduction The muscle injury, and more especially the hamstring strain, account for a large proportion of explosive top athletes injuries [1-3]. The subsequent down-time period has some sports and ... [more ▼]

Introduction The muscle injury, and more especially the hamstring strain, account for a large proportion of explosive top athletes injuries [1-3]. The subsequent down-time period has some sports and financial negatives consequences for the athlete, his team and/or his club [4, 5]. Despite the rehabilitation before return to play and prevention program, hamstring reinjury rates are still high (26% of all injuries) [6] and it's commonly accepted that a second injury is more severe than a first episode [2]. A more functional test could help the clinician in the return to play process decision to reduce the muscle injuries hamstring relapse. Purpose The aim of our methodology is to analyze, after medical clearance to resume sports activities, for athletes who suffered from grade II/III hamstring muscle strain, the biomechanics of the lower limbs during an explosive jump task. Method After (7,3±0,7 weeks) a grade II or III hamstring muscle tear, eight men (25±5,9 years), without past lower limb major injury, performed: - an isokinetic test (knee maximal flexion-extension in concentric at 60°.s-1 and 240°.s-1 and knee maximal flexion in eccentric at 30°.s-1); - a tridimensional biomechanics analysis of (bipodal and unipodal) squat jump and counter movement jump with Codamotion® system and Kistler® multicomponent force plates. Results A muscular lateral strength imbalance (±10% with p-value < 0,02) has been identified on the hamstring in concentric and eccentric by means of isokinetic testing, with the healthy side stronger than the pathologic. The main statistical significant outcome in the biomechanics analysis is the lower knee angle (±12% with p-value < 0,02) at the low point before the concentric pushing phase of the unipodal CMJ for the healthy leg than to the other one whereas there's no difference between both legs in an equivalent healthy population. Discussion & conclusion The tridimensional analysis appears to be complementary, not redundant, with the isokinetic strength testing due to the different nature of their informations obtained. It could be integrated in the return to play process decision expected the potentially interesting information about the player's biomechanics that it provides. References 1. Ekstrand, J., M. Hagglund, and M. Walden, Epidemiology of muscle injuries in professional football (soccer). Am J Sports Med, 2011. 39(6): p. 1226-32. 2. Ekstrand, J., M. Hagglund, and M. Walden, Injury incidence and injury patterns in professional football: the UEFA injury study. Br J Sports Med, 2011. 45(7): p. 553-8. 3. Lopez, V., Jr., et al., Profile of an American amateur rugby union sevens series. Am J Sports Med, 2012. 40(1): p. 179-84. 4. Price, R.J., et al., The Football Association medical research programme: an audit of injuries in academy youth football. Br J Sports Med, 2004. 38(4): p. 466-71. 5. Verrall, G.M., et al., Assessment of player performance following return to sport after hamstring muscle strain injury. J Sci Med Sport, 2006. 9(1-2): p. 87-90. 6. Brooks, J.H., et al., Incidence, risk, and prevention of hamstring muscle injuries in professional rugby union. Am J Sports Med, 2006. 34(8): p. 1297-306. [less ▲]

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See detailLight-to-moderate alcohol intake increases the risk of hepatocellular carcinoma in patients with HCV-related compensated cirrhosis: a prospective study.
Vandenbulcke, H; Moreno, C; Colle, I et al

in Acta Gastro-Enterologica Belgica (2016, March), 79(1), 01

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See detailSofosbuvir in combination with simeprevir +/- ribavirin in genotype 4 hepatitis C patients with advanced fibrosis or cirrhosis: real-life experience from Belgium
Moreno, C; Lasser, L; DELWAIDE, Jean ULiege et al

in Acta Gastro-Enterologica Belgica (2016, March), 79(1), 08

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See detailAzacytidine Enhances Regulatory T-Cells In Vivo and Prevents Experimental Xenogeneic Graft-Versus-Host Disease
Ehx, Grégory ULiege; Fransolet, Gilles ULiege; de Leval, Laurence ULiege et al

in Biology of Blood and Marrow Transplantation (2016, March), 22(3), 393

Background. The demethylating agent 5-azacytidine (AZA) has proven its efficacy as treatment for myelodysplastic syndrome and acute myeloid leukemia. In addition, AZA can demethylate FOXP3 intron 1 ... [more ▼]

Background. The demethylating agent 5-azacytidine (AZA) has proven its efficacy as treatment for myelodysplastic syndrome and acute myeloid leukemia. In addition, AZA can demethylate FOXP3 intron 1 (FOXP3i1) leading to the generation of regulatory T cells (Tregs). Objective. We investigated the impact of AZA on xenogeneic graft-versus-host disease (xGVHD) in a humanized murine model of transplantation, and described the impact of the drug on human T cells in vivo. Methods. In order to induce xGVHD, human peripheral blood mononuclear cells (huPBMC) were administered intravenously in NOD-scid IL-2Rγnull (NSG) mice. Results. AZA successfully improved both survival (p<0.0001) and xGVHD scores (p<0.0001). Further, AZA significantly decreased human T-cell proliferation as well as INF-γ and TNF-α serum levels, and reduced the expression of GRANZYME B and PERFORIN 1 by cytotoxic T cells. In addition, AZA administration significantly increased the function, proliferation and frequency of Tregs through demethylation of FOXP3i1 and higher secretion of IL-2 by conventional T cells due to IL2 gene promoter site 1 demethylation. Interestingly, among AZA-treated mice surviving the acute phase of xGVHD, there was an inverse correlation between the presence of Tregs and signs of chronic GVHD. Finally, Tregs harvested from the spleen of AZA-treated mice were suppressive and stable over time since they persisted at high frequency in secondary transplant experiments. Conclusion. These findings emphasize a potential role for AZA as prevention or treatment of GVHD and other autoimmune diseases. [less ▲]

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See detailBois, brique et fer : Approche multi-disciplinaire de la charpente de l'église Notre-Dame du Sablon, Bruxelles (RBC)
CREMER, Sarah; FRAITURE, Pascale; Hoffsummer, Patrick ULiege et al

in Archaeologia Mediaevalis (2016, March), 39

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See detailNewborn screening for sickle cell disease : 13 years at the CHR "La Citadelle", Liège
Sepulchre, Edith; Ketelslegers, Olivier; Minon, Jean-Marc et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2016, March), 18(1), 107

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See detailMulticenter Belgian experience of sofosbuvir medical need program in pre-and post-liver transplantation patients: safety and efficacy results.
Degré, D; Laleman, W; Verhelst, X et al

in Acta Gastro-Enterologica Belgica (2016, March), 79(1), 15

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See detailDiscovery of novel accessible proteins for therapeutic targeting of hepatocellular carcinoma.
Turtoi, Andrei ULiege; Otaka, Y; Rokudai, S et al

in Acta Gastro-Enterologica Belgica (2016, March), 79(1), 13

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See detailChattering-free Sliding Mode Control for Propellantless Rendez-vous using Differential Drag
Cho, Hancheol ULiege; Dell'Elce, Lamberto ULiege; Kerschen, Gaëtan ULiege

in International Conference on Astrodynamics Tools and Techniques (2016, March)

This paper develops a differential drag-based sliding mode controller for satellite rendez-vous. It is chattering-free and avoids bang-bang type control to adjust the relative motion more efficiently. In ... [more ▼]

This paper develops a differential drag-based sliding mode controller for satellite rendez-vous. It is chattering-free and avoids bang-bang type control to adjust the relative motion more efficiently. In spite of uncertain nonlinear perturbations and disturbances, it is shown that the in-plane relative motion between two satellites can be effectively controlled by regulating the drag difference. An adaptive tuning rule is also presented such that the errors are suppressed to lie within a desired error box. The proposed controller is simple and easy to implement in a small satellite, and numerical simulations are carried out to demonstrate its effectiveness in a high fidelity environment. [less ▲]

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See detailGenetics 2 Multiple fractures, genetics to the rescue!
HENNUY, Nadège ULiege; NYAMUGABO MUNYERE NKANA, Kindja ULiege; FLORKIN, Benoît ULiege et al

in Belgian Journal of Paediatrics (2016, March), 18(1), 63

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See detailThyroid-related bone lesions: clinical case
Tribolet, Sophie ULiege; Nicolescu, Ramona

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2016, March)

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See detailLINKING CATTLE GRAZING BEHAVIOR TO METHANE AND CARBON DIOXIDE DYNAMICS
Blaise, Yannick ULiege; Lebeau, Frédéric ULiege; Andriamandroso, Andriamasinoro ULiege et al

in Communications in Agricultural and Applied Biological Sciences (2016, February), 81(1), 107-112

Various methods are presently used to measure methane (CH4) emissions of ruminants on pasture. Those measurements are essential to evaluate nutritional strategies to mitigate enteric CH4 emissions as well ... [more ▼]

Various methods are presently used to measure methane (CH4) emissions of ruminants on pasture. Those measurements are essential to evaluate nutritional strategies to mitigate enteric CH4 emissions as well as addressing the selection of low producing individuals. On pasture and in the barn, variations in CH4 emissions are observed depending on the time of the day. However, no studies have been made to link these diurnal fluctuations to behavioural phases, especially on pasture. The aim of this study was to understand the individual dynamics of CH4 production and their links to the grazing behaviour. For this purpose, a new tool was specifically developed. Five red-pied dry cows were equipped with infrared CH4 and carbon dioxide (CO2) sensors measuring concentrations in the exhaled air at 4 Hz. The animals were equipped with a heart rate belt (HR) and motion sensors to detect their feeding behaviours (grazing vs. rumination) for periods of 8 h/d. Wind speed (WS) was also monitor to verify interference with sampled gas concentrations. Results showed that using the CH4:CO2 ratio reduced the interference with WS that was observed on raw CH4 and CO2 concentration signals. CH4:CO2 ratio average over 5 min periods indicated that CH4 emissions were lower during grazing than rumination (P<0.01). The eructation frequency during grazing (0.48 eructation/min, P<0.01) was also lower than during rumination (0.65 eructation/min). HR was higher during grazing that rumination. Because HR is usually linked to metabolic CO2 production intensity, hence influencing the denominator of the CH4:CO2 ratio, further investigation should focus on the quantification of changes in fermentative and metabolic CO2 emissions along the day to estimate total CH4 production more accurately and the relationship between CH4 emissions patterns and post-feeding times. [less ▲]

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See detailOverview of Superhydrophilic, Photocatalytic and Anticorrosive Properties of TiO2 Thin Films Doped with Multi-walled Carbon Nanotubes and Deposited on 316L Stainless Steel
Léonard, Géraldine ULiege; Remy, Simon; Heinrichs, Benoît ULiege

in Materials Today: Proceedings (2016, February), 3(2), 434-438

TiO2 films with MWCNTs are produced for anticorrosive applications to increase the lifetime of steel materials. TiO2 has two additional properties, photoactivity and superhydrophilicity. Two TiO2 samples ... [more ▼]

TiO2 films with MWCNTs are produced for anticorrosive applications to increase the lifetime of steel materials. TiO2 has two additional properties, photoactivity and superhydrophilicity. Two TiO2 samples, synthesized in aqueous or alcoholic media, have been doped with MWCNTs. The material which best combines anticorrosive, superhydrophilic and photocatalytic properties, is the one produced in aqueous medium (Aq-TiO2-CNT). Doping with MWCNTs increases the photodegradation of p-nitrophenol from 18% to 50%. MWCNTs allow to reduce the corrosion current and the corrosion potential. The good superhydrophilicity of TiO2 is kept on stainless steel with a contact angle after illumination around 5°. [less ▲]

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See detailComputed Tomography and Magnetic Resonance Findings in Athletes at Risk for Sudden Cardiac Death
Ghekiere, Olivier; Nchimi Longang, Alain ULiege; Bijnens, Eric et al

in Journal of the Belgian Society of Radiology (2016, February), 1

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See detailSuivi de quelques mammifères protégés en Wallonie.
Schockert, Vincianne ULiege; Lambinet, Clotilde ULiege; Libois, Roland ULiege

in FORÊT.NATURE (2016, February), 138

Depuis 2005, la "convention Mammifères" qui lie le SPW et l'U.Lg a pour but d'actualiser les connaissances sur les petits mammifères non volants en Wallonie: distribution et (micro-) habitats utilisés ... [more ▼]

Depuis 2005, la "convention Mammifères" qui lie le SPW et l'U.Lg a pour but d'actualiser les connaissances sur les petits mammifères non volants en Wallonie: distribution et (micro-) habitats utilisés. Ces 30 dernières années, quelques mesures ont eu un impact sur les populations: mise sous statut de protection, renforcement général de la règlementation environnementale (Natura 2000, code forestier...) et épizooties. Quelques exemples montrent la diversité et la spécificité des suivis nécessaires en vue d'évaluer leur état de conservation: cinq espèces de musaraignes protégées, la loutre, la martre, le muscardin et le blaireau. Pour ce dernier, la comparaison des niveaux de population et de dégâts de l'année 2012 démontre l'importance de disposer de données solides sur les populations pour éviter une révision inappropriée de leur statut [less ▲]

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See detailTrophic diversity of seagrass detritus copepods: A consequence of species-specific specialization or a random diet?
Mascart, Thibaud; De Troch, Marleen; Remy, François ULiege et al

in PeerJ PrePrints (2016, January 13), 4

One of the major ecological research questions is understanding how biodiversity influences ecosystem functioning. Unravelling interspecific feeding preferences of organisms with overlapping trophic ... [more ▼]

One of the major ecological research questions is understanding how biodiversity influences ecosystem functioning. Unravelling interspecific feeding preferences of organisms with overlapping trophic niches will give part of the answer. Subsequently, the present study displays the trophic diversity of a benthic copepod community in a North-Western Corsican Posidonia oceanica seagrass ecosystem. These seagrass meadows are often interrupted by bare sand patches serving as deposition area for loose detritus. The accumulated macrophytodetritus, mainly derived from senescent macrophytes, harbour a diverse community of Harpacticoida (Crustacea, Copepoda). The most abundant copepods (i.e. three harpacticoids and one calanoid, belonging to different eco-morphological types) and their potential food sources (i.e. macrophytodetritus, epiphytic biofilm and suspended organic matter) were analysed for stable isotope ratios (δ13C, δ15N) and total lipids content. The results revealed a harpacticoid copepod feeding preference towards the epiphytic biofilm, while calanoid copepods preferred suspended organic matter. Additionally, a species-specific composition variation revealed finer partitioning of food resources (e.g. different micro-organisms present in the biofilm like bacteria, diatoms, fungi) over time.In conclusion, results showed species-specific food preferences, resulting in trophic niche and resource partitioning. Every eco-morphological type seems to cope in different ways with temporal fluctuations of food sources to comply with their nutritional needs. This illustrates the high resilience of the copepod community present in macrophytodetritus accumulations. Moreover, our results underlined the importance of multiple biomarker species-specific analysis in trophic ecology studies, especially in complex and dynamic environments offering numerous food items to consumers. [less ▲]

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See detailCan we detect adaptive radiations in marine fishes?
Santini, Francesco; Carnevale, Giorgio; Marrama, Giuseppe et al

in Integrative and Comparative Biology (2016, January), 56

The concept of adaptive radiation, according to which a biological lineage undergoes elevated rates of species diversification while at the same time experiencing divergence along ecological axis, is ... [more ▼]

The concept of adaptive radiation, according to which a biological lineage undergoes elevated rates of species diversification while at the same time experiencing divergence along ecological axis, is often invoked in evolutionary studies to explain the astonishing diversity of groups such as the cichlids of the African rift lakes, silverswords plants and honeycreeper birds in Hawaii, and anole lizards in the Neotropics. Recent surveys of the scientific literature, however, revealed that most studies of adaptive radiation do not recover the expected signal of early burst of lineage diversification, and in several animal groups rates of cladogenesis and phenotypic evolution may often be unlinked, thus creating complex patterns in the tempo of lineage and trait diversification. Furthermore, in spite of the dramatic increase in number of studies of the tempo and mode of evolution in marine fishes during the past decade, very little evidence has been uncovered to support the idea that adaptive radiations played a role in generating their staggering diversity, and even when a signal of radiation is recovered this virtually never conforms to the “traditional” early burst scenario. Using examples from our research on diverse groups of marine teleost fishes such as jacks and allies (Carangoidei), pufferfish and allies (Tetraodontiformes) and snappers (Lutjanidae), we will discuss why it is so difficult to recover a signal of adaptive radiation in general, and early burst in particular, and offer some suggestions on how to test for these patterns. [less ▲]

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See detailEn-deçà du langage : Communauté et historicité de l’antéprédicatif selon Heidegger
Zincq, Aurélien ULiege

in Bulletin d'Analyse Phénoménologique (2016), XII(2), 251-274

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See detailChatter mitigation using the nonlinear tuned vibration absorber
Habib, G.; Kerschen, Gaëtan ULiege; Stepan, Gabor

in Proceedings of ISMA 2016 - International Conference on Noise and Vibration Engineering and USD2016 - International Conference on Uncertainty in Structural Dynamics (2016)

A passive vibration absorber, termed the nonlinear tuned vibration absorber (NLTVA), is designed for the suppression of chatter vibrations. Differently from most passive vibration absorbers proposed in ... [more ▼]

A passive vibration absorber, termed the nonlinear tuned vibration absorber (NLTVA), is designed for the suppression of chatter vibrations. Differently from most passive vibration absorbers proposed in the literature, the NLTVA comprises both a linear and a nonlinear restoring force. Its linear characteristics are tuned in order to optimize the stability properties of the machining operation, while its nonlinear properties are chosen in order to control the bifurcation behavior of the system and guarantee robustness of stable operation. In this work, the NLTVA is applied to turning machining. [less ▲]

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See detailImportance of Metabolism Variations in a Model of Extracorporeal Carbon Dioxide Removal
Habran, Simon ULiege; Desaive, Thomas ULiege; MORIMONT, Philippe ULiege et al

in Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society (2016)

Extracorporeal CO2 Removal device is used in clinics when a patient suffers from a pulmonary insufficiency like Acute Respiratory Distress Syndrome and allows to decarboxylate blood externally. In this ... [more ▼]

Extracorporeal CO2 Removal device is used in clinics when a patient suffers from a pulmonary insufficiency like Acute Respiratory Distress Syndrome and allows to decarboxylate blood externally. In this work, a model of the respiratory system coupled with such a device is proposed to analyze the decrease of CO2 partial pressure in blood. To validate the model, some parameters are estimated thanks to experimental data. Metabolism is a crucial parameter and we show that its time evolution must be taken into account in order to have correct CO2 partial pressure simulations in arteries and in veins. [less ▲]

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See detailProjet Neworld: Evaluation informatisée des capacités de multitâches en neuropsychiatrie
Laloyaux, Julien ULiege; Van Der Linden, M; Levaux, M-N et al

in Encéphale (L') (2016)

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See detailApports de l'électrophysiologie à la médecine d'expertise
WANG, François-Charles ULiege

in Consilio manuque (2016), 1

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See detailEpisodic memory and aging: The effect of perceptual processing fluency on recognition memory processes
Bastin, Christine ULiege; Willems, Sylvie ULiege

in Journal of Cognitive Neuroscience (2016), S2016

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See detailDo Burundians have a more positive perception of older people than immigrants or Belgians?
Marquet, Manon ULiege; Missotten, Pierre ULiege; Nindaba, Desiderate et al

in International Psychogeriatrics (2016), 27(Supplement 1), 70-172

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See detailThe impact of factors related to retirement on cognitive functioning
Grotz, Catherine ULiege; Adam, Stéphane ULiege; Matharan, Fanny et al

in International Psychogeriatrics (2016), 27(supplement S1), 45-69

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See detailDo the elderly feel older after exposure to negative aging stereotypes?
Marquet, Manon ULiege; Missotten, Pierre ULiege; Adam, Stéphane ULiege

in International Psychogeriatrics (2016), 27(Supplement 1), 70-172

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See detailPerformance comparison between a nonlinear energy sink and a linear tuned vibration absorber for broadband control
Gourc, E.; Elce, L. D.; Kerschen, Gaëtan ULiege et al

in Conference Proceedings of the Society for Experimental Mechanics Series (2016), 1

The performance of a linear tuned vibration absorber (LTVA) and a nonlinear energy sink (NES) for the vibration mitigation of an uncertain linear primary system is investigated. An analytic tuning rule ... [more ▼]

The performance of a linear tuned vibration absorber (LTVA) and a nonlinear energy sink (NES) for the vibration mitigation of an uncertain linear primary system is investigated. An analytic tuning rule for the LTVA when the primary system contains uncertainty is derived. The behavior of the linear system coupled to the NES is analyzed theoretically. A tuning methodology for the NES in the deterministic as well as for the uncertain case is presented. © The Society for Experimental Mechanics, Inc. 2016. [less ▲]

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See detailEnglish translation and cross-cultural adaptation of the SARQOL Questionnaire
Beaudart, Charlotte ULiege; Edwards, M.; Dennisson, E. et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 58

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See detailOptical characterization of Sol-Gel ZnO:Al thin films
Ivanova, T; Harizanova, A; Koutzarova, T et al

in Journal of Physics: Conference Series (2016), 700

This paper presents a sol-gel technological process for preparing thin films of ZnO and ZnO:Al. The effect of annealing treatments (500, 600, 700 and 800 oC) on their properties was studied. The ... [more ▼]

This paper presents a sol-gel technological process for preparing thin films of ZnO and ZnO:Al. The effect of annealing treatments (500, 600, 700 and 800 oC) on their properties was studied. The structural evolution with the temperature was investigated by using X-Ray diffraction (XRD). Fourier Transform Infrared (FTIR) and UV-VIS spectrophotometry were applied to characterizing the films’ vibrational and optical properties. The ZnO and ZnO:Al films possessed a polycrystalline structure. The films studied are highly transparent in the visible spectral range. The optical band gap values and the haze parameter were also determined. [less ▲]

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See detailInvestigation of sol-gel yttrium doped ZnO thin films: structural and optical properties
Ivanova, T; Harizanova, A; Koutzarova, T et al

in Journal of Physics: Conference Series (2016)

Nanostructured metal oxide films are extensively studied due to their numerous applications such as optoelectronic devices, sensors. In this work, we report the Y–Zn–O nanostructured films prepared by sol ... [more ▼]

Nanostructured metal oxide films are extensively studied due to their numerous applications such as optoelectronic devices, sensors. In this work, we report the Y–Zn–O nanostructured films prepared by sol-gel technology from sols with different concentration of yttrium precursor, followed by post-annealing treatment. The Y doped ZnO thin films have been deposited on Si and quartz substrates by spin coating method, then treated at températures ranging from 300-800°C. XRD analysis reveals modification of the film structure and phases in the doped ZnO films. [less ▲]

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See detailPrevalence of frailty among nursing home, according to different operational definitions
Buckinx, Fanny ULiege; Reginster, Jean-Yves ULiege; GILLAIN, Sophie ULiege et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 69

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See detailPhysical and muscle performances among elderly nursing home residents. Results fo the senior cohort
Buckinx, Fanny ULiege; Reginster, Jean-Yves ULiege; CROISIER, Jean-Louis ULiege et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 69

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See detailRandomized, Double-Blinded, Controlled Clinical Trial Evaluating the Efficacy of a Diet Supplemented with Curcuminoids Extract, Hydrolysed Collagen and Green Tea Extract in Dogs with Osteoarthritis
Barthélémy, Nicolas; Comblain, Fanny ULiege; Lesponne, Isabelle et al

in Veterinary and Comparative Orthopaedics and Traumatology (2016)

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See detailPermutations and shifts
Charlier, Emilie ULiege

in Lecture Notes in Computer Science (2016), 9840

The entropy of a symbolic dynamical system is usually defined in terms of the growth rate of the number of distinct allowed factors of length $n$. Bandt, Keller and Pompe showed that, for piecewise ... [more ▼]

The entropy of a symbolic dynamical system is usually defined in terms of the growth rate of the number of distinct allowed factors of length $n$. Bandt, Keller and Pompe showed that, for piecewise monotone interval maps, the entropy is also given by the number of permutations defined by consecutive elements in the trajectory of a point. This result is the starting point of several works of Elizalde where he investigates permutations in shift systems, notably in full shifts and in beta-shifts. The goal of this talk is to survey Elizalde's results. I will end by mentioning the case of negative beta-shifts, which has been simultaneously studied by Elizalde and Moore on the one hand, and by Steiner and myself on the other hand. [less ▲]

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See detailA Brief History of MPLS Usage in IPv6
Vanaubel, Yves ULiege; Mérindol, Pascal; Pansiot, Jean-Jacques et al

in Lecture Notes in Computer Science (2016)

Recent researches have stated the fast deployment of IPv6. It has been demonstrated that IPv6 grows much faster, being so more and more adopted by both Internet service providers but also by servers and ... [more ▼]

Recent researches have stated the fast deployment of IPv6. It has been demonstrated that IPv6 grows much faster, being so more and more adopted by both Internet service providers but also by servers and end-hosts. In parallel, researches have been conducted to discover and assess the usage of MPLS tunnels. Indeed, recent developments in the ICMP protocol make certain categories of MPLS tunnels transparent to traceroute probing. However, these studies focus only on IPv4, where MPLS is strongly deployed. In this paper, we provide a first look at how MPLS is used under IPv6 networks using traceroute data collected by CAIDA. At first glance, we observe that the MPLS deployment and usage seem to greatly differ between IPv4 and IPv6, in particular in the way MPLS label stacks are used. While label stacks with at least two labels are marginal in IPv4 (and mostly correspond to a VPN usage), they are prevalent in IPv6. After a deeper analysis of the label stack typical content in IPv6, we show that such tunnels result from the use of 6PE. This is not really surprising since this mechanism was specifically designed to forward IPv6 traffic using MPLS tunnels through networks that are not fully IPv6 compliant. However, we show that it does not result from non dual-stack routers but rather from the absence of native IPv6 MPLS signaling protocols. Finally, we investigate a large Tier-1 network, Cogent, that stands out with an original set-up. [less ▲]

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See detailPsychometric properties of the Questionnaire of Executive Self-Awareness (QESA) for Children
Geurten, Marie ULiege; Catale, Corinne ULiege; Geurten, Claire ULiege et al

in Journal of the International Neuropsychological Society (2016)

Objective: People with accurate representations of their own cognitive functioning (i.e., cognitive self-awareness) tend to use appropriate strategies to regulate their behavior. Due to the lack of ... [more ▼]

Objective: People with accurate representations of their own cognitive functioning (i.e., cognitive self-awareness) tend to use appropriate strategies to regulate their behavior. Due to the lack of appropriate instruments, few studies have examined the development of this ability among children. Method: This study tested the measurement properties of the self-rating and other-rating forms of the Questionnaire of Executive Self-Awareness (QESA), designed to tap children’s knowledge of their executive functioning. Participants were 317 children aged 7 to 14 years old. Results: Confirmatory factor analyses carried out on the QESA confirmed the eight-factor structure of both versions. There were significant correlations between the QESA and the parent versions of the BRIEF, DEX-C, and CHEXI. Both forms of the QESA were able to distinguish between children who had sustained a traumatic brain injury (TBI) and control participants. A self-other discrepancy score was computed to assess children’s executive self-awareness. A statistical difference was observed between the TBI and control groups on this score, suggesting that TBI may trigger self-awareness impairments in children. Conclusion: The good psychometric properties of the two forms of the QESA were established. Furthermore, results of the analyses carried on the different discrepancy scores seem to indicate that the QESA could help clinicians to detect patients with self-awareness deficits. [less ▲]

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See detailIncidence of bone fractures after critical illness
ROUSSEAU, Anne-Françoise ULiege; Michel, Laure ULiege; Bawin, Maxime ULiege et al

in Intensive Care Medicine Experimental (2016), 4(Suppl 1), 1131

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