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See detailOverview of Superhydrophilic, Photocatalytic and Anticorrosive Properties of TiO2 Thin Films Doped with Multi-walled Carbon Nanotubes and Deposited on 316L Stainless Steel
Léonard, Géraldine ULg; Remy, Simon; Heinrichs, Benoît ULg

in Materials Today: Proceedings (2016, February), 3(2), 434-438

TiO2 films with MWCNTs are produced for anticorrosive applications to increase the lifetime of steel materials. TiO2 has two additional properties, photoactivity and superhydrophilicity. Two TiO2 samples ... [more ▼]

TiO2 films with MWCNTs are produced for anticorrosive applications to increase the lifetime of steel materials. TiO2 has two additional properties, photoactivity and superhydrophilicity. Two TiO2 samples, synthesized in aqueous or alcoholic media, have been doped with MWCNTs. The material which best combines anticorrosive, superhydrophilic and photocatalytic properties, is the one produced in aqueous medium (Aq-TiO2-CNT). Doping with MWCNTs increases the photodegradation of p-nitrophenol from 18% to 50%. MWCNTs allow to reduce the corrosion current and the corrosion potential. The good superhydrophilicity of TiO2 is kept on stainless steel with a contact angle after illumination around 5°. [less ▲]

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See detailTrophic diversity of seagrass detritus copepods: A consequence of species-specific specialization or a random diet?
Mascart, Thibaud; De Troch, Marleen; Remy, François ULg et al

in PeerJ PrePrints (2016, January 13), 4

One of the major ecological research questions is understanding how biodiversity influences ecosystem functioning. Unravelling interspecific feeding preferences of organisms with overlapping trophic ... [more ▼]

One of the major ecological research questions is understanding how biodiversity influences ecosystem functioning. Unravelling interspecific feeding preferences of organisms with overlapping trophic niches will give part of the answer. Subsequently, the present study displays the trophic diversity of a benthic copepod community in a North-Western Corsican Posidonia oceanica seagrass ecosystem. These seagrass meadows are often interrupted by bare sand patches serving as deposition area for loose detritus. The accumulated macrophytodetritus, mainly derived from senescent macrophytes, harbour a diverse community of Harpacticoida (Crustacea, Copepoda). The most abundant copepods (i.e. three harpacticoids and one calanoid, belonging to different eco-morphological types) and their potential food sources (i.e. macrophytodetritus, epiphytic biofilm and suspended organic matter) were analysed for stable isotope ratios (δ13C, δ15N) and total lipids content. The results revealed a harpacticoid copepod feeding preference towards the epiphytic biofilm, while calanoid copepods preferred suspended organic matter. Additionally, a species-specific composition variation revealed finer partitioning of food resources (e.g. different micro-organisms present in the biofilm like bacteria, diatoms, fungi) over time.In conclusion, results showed species-specific food preferences, resulting in trophic niche and resource partitioning. Every eco-morphological type seems to cope in different ways with temporal fluctuations of food sources to comply with their nutritional needs. This illustrates the high resilience of the copepod community present in macrophytodetritus accumulations. Moreover, our results underlined the importance of multiple biomarker species-specific analysis in trophic ecology studies, especially in complex and dynamic environments offering numerous food items to consumers. [less ▲]

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See detailCan we detect adaptive radiations in marine fishes?
Santini, Francesco; Carnevale, Giorgio; Marrama, Giuseppe et al

in Integrative and Comparative Biology (2016, January), 56

The concept of adaptive radiation, according to which a biological lineage undergoes elevated rates of species diversification while at the same time experiencing divergence along ecological axis, is ... [more ▼]

The concept of adaptive radiation, according to which a biological lineage undergoes elevated rates of species diversification while at the same time experiencing divergence along ecological axis, is often invoked in evolutionary studies to explain the astonishing diversity of groups such as the cichlids of the African rift lakes, silverswords plants and honeycreeper birds in Hawaii, and anole lizards in the Neotropics. Recent surveys of the scientific literature, however, revealed that most studies of adaptive radiation do not recover the expected signal of early burst of lineage diversification, and in several animal groups rates of cladogenesis and phenotypic evolution may often be unlinked, thus creating complex patterns in the tempo of lineage and trait diversification. Furthermore, in spite of the dramatic increase in number of studies of the tempo and mode of evolution in marine fishes during the past decade, very little evidence has been uncovered to support the idea that adaptive radiations played a role in generating their staggering diversity, and even when a signal of radiation is recovered this virtually never conforms to the “traditional” early burst scenario. Using examples from our research on diverse groups of marine teleost fishes such as jacks and allies (Carangoidei), pufferfish and allies (Tetraodontiformes) and snappers (Lutjanidae), we will discuss why it is so difficult to recover a signal of adaptive radiation in general, and early burst in particular, and offer some suggestions on how to test for these patterns. [less ▲]

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See detailProjet Neworld: Evaluation informatisée des capacités de multitâches en neuropsychiatrie
Laloyaux, Julien ULg; Van Der Linden, M; Levaux, M-N et al

in Encéphale (L') (2016)

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See detailAvelumab (MSB0010718C ; anti-PD-L1) as a first-line treatment for patients with advanced NSCLC from the JAVELIN Solid Tumor phase 1b trial : safety, clinical activity, and PD-L1 expression
Verschraegen, C.; Chen, F.L.; Spigel, D.R. et al

in Journal of Clinical Oncology (2016), 34

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See detailApports de l'électrophysiologie à la médecine d'expertise
WANG, François-Charles ULg

in Consilio manuque (2016), 1

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See detailHistoire et expérience fondatrice dans Sein und Zeit
Zincq, Aurélien ULg

in Bulletin d'Analyse Phénoménologique (2016)

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See detailEpisodic memory and aging: The effect of perceptual processing fluency on recognition memory processes
Bastin, Christine ULg; Willems, Sylvie ULg

in Journal of Cognitive Neuroscience (2016), S2016

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See detail'En fonction du futur': la fonction publique régionale wallonne sous contrainte d'innovation
Claisse, Frédéric ULg; Guyot, Jean-Luc

in Prospective et Stratégie (2016), 1(7), 39-58

Building on a forward-looking reflexion initiated at the Walloon Institute for Evaluation, Foresight and Statistics (IWEPS), the paper considers the issues at stake for the transformation of the regional ... [more ▼]

Building on a forward-looking reflexion initiated at the Walloon Institute for Evaluation, Foresight and Statistics (IWEPS), the paper considers the issues at stake for the transformation of the regional Walloon public administration, taken as a changing environment under strong pressures – institutional, budgetary, demographic, economic and ideological –. In another perspective, these multiple constraints can also be seen as opportunities to innovate and to think about the public administration identity, modes of organisation and ways of performing its missions : how is the profession of civil servant going to be redefined, at a time when the proportion of contract employees vs. public servants has never been so high? What management practices can the administration draw inspiration from, as New Public Management (NPM) principles are showing some signs of exhaustion? What changes can be observed in the users’ expectations towards the administration? What role will instruments of digital governance play in this new configuration? How will the public administration react to the competition of new providers of services to the public? [less ▲]

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See detailEn-deçà du langage : Communauté et historicité de l’antéprédicatif selon Heidegger
Zincq, Aurélien ULg

in Bulletin d'Analyse Phénoménologique (2016), XII(2), 251-274

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See detailAntonymie et exhaustivité
Steffens, Marie ULg

in SHS Web of Conferences (2016), 27

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See detailadministration of Third-Party Mesenchymal Stromal Cells at the Time of Kidney Transplantation: Interim Safety Analysis at One-Year Follow-Up
WEEKERS, Laurent ULg; Erpicum, Pauline ULg; DETRY, Olivier ULg et al

in Transplant International (2016), 29(Suppl 2), 13-6

Objective. Mesenchymal stromal cells (MSC) therapy has been suggested in kidney transplantation (KTx). We report on the 1-year follow-up of an open-label phase I trial using MSC at the time of KTx ... [more ▼]

Objective. Mesenchymal stromal cells (MSC) therapy has been suggested in kidney transplantation (KTx). We report on the 1-year follow-up of an open-label phase I trial using MSC at the time of KTx. Methods. On postoperative day 3 (D3), third-party MSC (~2.0x106/kg) were administered to 7 non-immunized first-transplant recipients from deceased donors, under standard immunosuppression (Basiliximab, Tacrolimus, MMF and steroids). No HLA matching was required for MSC donors. In parallel, 7 comparable KTx recipients were included as controls. Written informed consent was obtained from all participants. Results. No hemodynamic or immune-allergic side-effect was noted at the time of MSC injection. Still, 1 patient with a history of ischemic heart disease had a NSTEMI ~3h after MSC infusion. Four MSC patients presented with CMV reactivation within 165 ± 96 days post KTx, whereas 3 controls had positive polyoma-BK viremia within 92 ± 4d post KTx. Three MSC patients were affected by pneumonia within 269 ± 98d post KTx, whereas 3 controls had urinary infection within 48 ± 43d post KTx. No MSC engraftment syndrome was observed. At D14, eGFR in MSC and control groups was 47.1 ± 6.8 and 39.7 ± 5.9 ml/min, respectively (p, 0.05). At 1 year, eGFR in MSC and control groups was 43.1 ± 17.8 and 53.9 ± 13.4 ml/min, respectively (p, 0.25). At 3-month protocol biopsy, no rejection was evidenced in MSC or control patients. Later on, 1 acute rejection was diagnosed at D330 in 1 MSC patient. No biopsy-proven AR was noted in controls. Three patients developed anti-HLA antibodies against MSC (n=1) or shared kidney/MSC (n=2) mismatches. Conclusions. MSC infusion was safe in all patients except one. Incidence of opportunist and non-opportunist infections was similar in both MSC and control groups. No MSC engraftment syndrome was documented. No difference in eGFR was found at 1 year post KTx. Putative immunization against MSC was observed in 3 patients. [less ▲]

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See detailAssociation between vertebral heart score measurement and overweight condition in dogs
François, Marion; Merveille, Anne-Christine ULg; Mc Entee, Kathleen ULg et al

in Veterinary Radiology & Ultrasound (2016)

Introduction Vertebral heart score (VHS) is used to assess heart size on thoracic radiographs. Association between VHS and overweight condition in dogs of different breeds is still unknown. The aim of ... [more ▼]

Introduction Vertebral heart score (VHS) is used to assess heart size on thoracic radiographs. Association between VHS and overweight condition in dogs of different breeds is still unknown. The aim of this study is to determine if VHS is influenced by overweight condition in dogs. The hypothesis is that VHS is influenced by BCS and T4 ratio. Methods Recruitment criteria for this retrospective study were the presence of a minimum of 2 thoracic radiographic views and a diagnosis of “normal echocardiographic examination” in medical records from 2013 to 2016. Body weight, BCS and breed were extracted. VHS and overweight condition were calculated. Dogs from breeds with a normal maximal VHS < 11 (group 1) and from breeds with a normal maximal VHS > 11 (group 2) were separated. Statistical analyses were performed using XLStat® software. Results Fifty-one dogs were included in the study. Body weight ranged from 3.7 to 44.8 kg and was not recorded in 2 dogs. These dogs were not excluded because of the BCS was recorded for these dogs. BCS ranged from 3 to 9. Thirteen dogs had a VHS value superior to the normal range and all of them had BCS ≥ 4. A weak positive correlation was found between BCS and T4 ratio (P ≤ 0.001, R2=0.4). There was a positive relationship between BCS and VHS (ANCOVA, P ≤ 0.003) for each group and between T4 ratio and VHS for each group (ANCOVA, P ≤ 0.001). Discussion/Conclusions This study confirms that the T4 ratio is correlated to BCS evaluated clinically. This ratio could be used to assess overweight condition on thoracic radiographs. VHS is influenced by BCS and the T4 ratio; therefore, VHS should be use with caution in overweighed dogs. [less ▲]

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See detailDo the elderly feel older after exposure to negative aging stereotypes?
Marquet, Manon ULg; Missotten, Pierre ULg; Adam, Stéphane ULg

in International Psychogeriatrics (2016), 27(Supplement 1), 70-172

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See detailPhysical and muscle performances among elderly nursing home residents. Results fo the senior cohort
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; CROISIER, Jean-Louis ULg et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 69

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See detailAgeism among nurses in oncology
Schroyen, Sarah ULg; Missotten, Pierre ULg; Jerusalem, Guy ULg et al

in International Psychogeriatrics (2016)

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See detailCircadian and homeostatic sleep pressure modulate fMRI correlates of vigilant attention
Muto, Vincenzo ULg; Jaspar, Mathieu ULg; Meyer, C et al

in Journal of Sleep Research (2016), 25(s1),

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See detailInfluence of crossed fields in structures combining large grain, bulk (RE)BCO superconductors and soft ferromagnetic discs
Philippe, Matthieu ULg; Fagnard, Jean-François ULg; Wera, Laurent ULg et al

in Journal of Physics: Conference Series (2016), 695

Bulk (RE)BCO superconductors are able to trap record magnetic fields and can be used as powerful permanent magnets in various engineering applications such as rotating machines and magnetic bearings. When ... [more ▼]

Bulk (RE)BCO superconductors are able to trap record magnetic fields and can be used as powerful permanent magnets in various engineering applications such as rotating machines and magnetic bearings. When such superconducting (SC) “trapped field magnets” are combined to a ferromagnetic (FM) disc, the total magnetic moment is increased with respect to that of the superconductor alone. In the present work, we study experimentally the magnetic behaviour of such hybrid FM/SC structures when they are subjected to cycles of applied field that are orthogonal to their permanent magnetization, i.e. a “crossed-field” configuration. Experimental results show that the usual “crossed-field demagnetization” caused by the cycles of transverse field is strongly reduced in the presence of the ferromagnet. [less ▲]

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See detailDiffusion MRI for following tumor modifications after neoadjuvant radiotherapy.
LALLEMAND, François ULg; Leroi, Natacha ULg; Bahri, Mohamed Ali ULg et al

in Radiotherapy & Oncology (2016), 119

Neoadjuvant radiotherapy (NeoRT) improves tumor local control and tumor resection in many cancers. The timing between the end of the NeoRT and surgery is driven by the occurrence of side effects or the ... [more ▼]

Neoadjuvant radiotherapy (NeoRT) improves tumor local control and tumor resection in many cancers. The timing between the end of the NeoRT and surgery is driven by the occurrence of side effects or the tumor downsizing. Some studies demonstrated that the timing of surgery and the RT schedule could influence tumor dissemination and subsequently patient overall survival. We demonstrated the impact of NeoRT on metastatic spreading in a Scid mice model. After an irradiation of 2x5gy, we show more metastasis in the lung when the mice are operated at day 4 compared to day 11. Here, our aim is to evaluate with functional MRI (fMRI) the impact of the radiation treatment on the tumor microenvironment and subsequently to identify non-invasive markers helping to determine the best timing to perform surgery for avoiding tumor spreading. [less ▲]

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See detailEnd-to-end continuous manufacturing
Monbaliu, Jean-Christophe ULg

in ChemistryViews (2016)

We will discuss the development and implementation of continuous-flow multistep strategies for the synthesis of high-value added organic targets. Selected examples include unusual reaction conditions such ... [more ▼]

We will discuss the development and implementation of continuous-flow multistep strategies for the synthesis of high-value added organic targets. Selected examples include unusual reaction conditions such as working with solids in microreactors, high temperature reactions and the handling of highly reactive species. [less ▲]

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See detailEnquêter sur les non-publics de la culture: quelle posture de recherche pour quel dispositif méthodologique?
Ghebaur, Cosmina ULg

in Questions de Communication (2016)

Mes travaux portent sur les non-publics de la culture et leur fabrication institutionnelle, à savoir leur production par les institutions chargées de mettre en œuvre sur un territoire donné les politiques ... [more ▼]

Mes travaux portent sur les non-publics de la culture et leur fabrication institutionnelle, à savoir leur production par les institutions chargées de mettre en œuvre sur un territoire donné les politiques culturelles les concernant. Pour explorer cette question, je me place dans la perspective initiée en sociologie de l'art par Pascale Ancel et Alain Pessin (2004) et caractérisée par la remise en question de la frontière entre publics et non-publics. On peut, écrit Martine Azam (2004), être " à la fois " public et non-public s'agissant de deux objets culturels différents ou du même objet à des moments différents. L'objectif de cet article est d'expliciter les principaux choix méthodologiques que j'ai été amenée à faire en enquêtant, avec cette posture de recherche, sur une exposition photographique en extérieur organisée dans une ville de la banlieue parisienne. [less ▲]

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See detailStudy of the Potential Zoonotic Transmission of Clostridium difficile in Belgian Cattle Farms.
Rodriguez Diaz, Cristina ULg; Hakimi, Djalal-Eddine; Daube, Georges ULg et al

in Journal of Food Protection (2016), 79(supplement A),

Introduction: Zoonoses are infectious that can be transmitted between animals and humans through direct contact, close proximity or the environment. Since domestic and food animals frequently test ... [more ▼]

Introduction: Zoonoses are infectious that can be transmitted between animals and humans through direct contact, close proximity or the environment. Since domestic and food animals frequently test positive for the bacterium, it seems plausible that C. difficile could be zoonotic. A former study showed that the prevalence in veal calf aged less than 6 months was 22% while in adult cattle population, it was 6,9 %. Purpose: This study aimed to determine the prevalence and the epidemiology of C. difficile in cattle farms and the possible spread of the bacterium among animals and farmers. Methods: A total of 176 faecal samples of cattle were collected from 5 different Belgian farms (south East Belgium), from November 2015 to February 2016. A stool sample of each farmer was also requested. Detection of C. difficile was performed by classical culture on C. difficile selective medium (cycloserine cefoxitin fructose cholate). Isolates were characterised by PCR-ribotyping and Genotype Cdiff test (Hain Lifescience), which allows the detection of all toxin genes, mutations in gyrA gene and the deletion in the regulator gene tcdC. Toxic activity was confirmed by a cytotoxic assay on MRC-5 cells. Results: C. difficile was detected in 14/178 (7.9%) animal samples. Isolates were grouped into five different types, including PCR-ribotype 015 (this ribotype is one the most encountered in hospitals in Belgium). The other types were UCL46A, UCL24*, UCL24, UCL33. All of them were identified as toxigenic by cytotoxicity assay and toxin genes profile. In contrast, none of the 5 farmers studied were positive for the bacterium. Significance: Results obtained indicate that PCR-ribotypes commonly isolated from hospitalised patients are also present in cattle, indicating an animal reservoir. However, a zoonotic transmission could be not demonstrated in this preliminary study. [less ▲]

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See detailPrevalence of vasculare risk factors in different stages of prodromal Alzheimer’s disease and its influence on cognitive decline
Bos, I.; Vos, S.; Frölich, L. et al

in Alzheimer's & Dementia : The Journal of the Alzheimer's Association (2016), 12(7), 1059-1061

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See detailЛексико-семантическое калькирование в финансово-экономической сфере
Kolyaseva, Alena ULg

in Новая экономика и региональная наука (New economy and the regional science), #2 (5) (2016)

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See detailPermutations and shifts
Charlier, Emilie ULg

in Lecture Notes in Computer Science (2016), 9840

The entropy of a symbolic dynamical system is usually defined in terms of the growth rate of the number of distinct allowed factors of length $n$. Bandt, Keller and Pompe showed that, for piecewise ... [more ▼]

The entropy of a symbolic dynamical system is usually defined in terms of the growth rate of the number of distinct allowed factors of length $n$. Bandt, Keller and Pompe showed that, for piecewise monotone interval maps, the entropy is also given by the number of permutations defined by consecutive elements in the trajectory of a point. This result is the starting point of several works of Elizalde where he investigates permutations in shift systems, notably in full shifts and in beta-shifts. The goal of this talk is to survey Elizalde's results. I will end by mentioning the case of negative beta-shifts, which has been simultaneously studied by Elizalde and Moore on the one hand, and by Steiner and myself on the other hand. [less ▲]

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See detailCharacteristics and frequency of large submarine landslides at the western tip of the Gulf of Corinth
Beckers, Arnaud; Hubert, Aurelia ULg; Beck, Christian et al

in Geophysical Research Abstracts (2016), 18

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See detailPsychometric properties of the Questionnaire of Executive Self-Awareness (QESA) for Children
Geurten, Marie ULg; Catale, Corinne ULg; Geurten, Claire ULg et al

in Journal of the International Neuropsychological Society (2016)

Objective: People with accurate representations of their own cognitive functioning (i.e., cognitive self-awareness) tend to use appropriate strategies to regulate their behavior. Due to the lack of ... [more ▼]

Objective: People with accurate representations of their own cognitive functioning (i.e., cognitive self-awareness) tend to use appropriate strategies to regulate their behavior. Due to the lack of appropriate instruments, few studies have examined the development of this ability among children. Method: This study tested the measurement properties of the self-rating and other-rating forms of the Questionnaire of Executive Self-Awareness (QESA), designed to tap children’s knowledge of their executive functioning. Participants were 317 children aged 7 to 14 years old. Results: Confirmatory factor analyses carried out on the QESA confirmed the eight-factor structure of both versions. There were significant correlations between the QESA and the parent versions of the BRIEF, DEX-C, and CHEXI. Both forms of the QESA were able to distinguish between children who had sustained a traumatic brain injury (TBI) and control participants. A self-other discrepancy score was computed to assess children’s executive self-awareness. A statistical difference was observed between the TBI and control groups on this score, suggesting that TBI may trigger self-awareness impairments in children. Conclusion: The good psychometric properties of the two forms of the QESA were established. Furthermore, results of the analyses carried on the different discrepancy scores seem to indicate that the QESA could help clinicians to detect patients with self-awareness deficits. [less ▲]

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See detailUrban infrastructure resilience to fire disaster: An overview
Gernay, Thomas ULg; Selamet, Serdar; Tondini, Nicola et al

in Procedia Engineering (2016), 161C

Fire disasters are a serious threat to the functionality of the built environment, in particular in densely populated urban areas where city infrastructure systems are under strain. Yet, fire safety ... [more ▼]

Fire disasters are a serious threat to the functionality of the built environment, in particular in densely populated urban areas where city infrastructure systems are under strain. Yet, fire safety issues are still mostly considered at the level of individual elements or buildings, disregarding the global risk for systems’ functionality. In line with the current efforts toward ensuring more resilient cities, this paper presents an overview of urban infrastructure resilience to fire disaster. The definitions of resilience and the quantitative frameworks established for other hazards such as earthquakes are reviewed. Then, the specificities of structural fire engineering are presented and it is shown how resilience frameworks could be applied to fire hazard. Finally, the paper identifies areas where further research efforts are needed. [less ▲]

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See detailThe effect of napping on the consolidation of explicit and implicit information
van Schalkwijk, F J; Heib, D P J; Hoedlmoser, K et al

in Journal of Sleep Research (2016), 25(s1),

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See detailConclusions des journées d’étude "Cher Monsieur Madrane"
Fierens, Jacques ULg

in Journal du Droit des Jeunes (2016), 354

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See detailBrain-derived neurotrophic factor (BDNF) in normal healthy and hemodialyzed populations
CAVALIER, Etienne ULg; Carlisi, A.S.; WATAR, Florence ULg et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 116

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See detailFunctional respiratory imagning-aided virtual preoperative planning in nasal surgery: towards a personalized approach.
Ansari, Edward; Vos, Wim; Van Holsbeke, Cedric et al

in B-ENT (2016)

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See detailPrevalence of concomitant bone and muscle wasting in patients from the SarcoPhAge Study
Locquet, Médéa ULg; Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 84

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See detailDo Burundians have a more positive perception of older people than immigrants or Belgians?
Marquet, Manon ULg; Missotten, Pierre ULg; Nindaba, Desiderate et al

in International Psychogeriatrics (2016), 27(Supplement 1), 70-172

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See detailImplementation of the green payment within the scheme of the new Common Agricultural Policy (2015-2020): first results for 2015 in Wallonia (South of Belgium)
Burny, Philippe ULg; Terrones Gavira, François ULg

in Quality-Access to Success (2016), (Supplement), 10-14

At the end of 2013, a new Common Agricultural Policy was defined at the European level, including the implementation of the so-called “green payment”, which obliges farmers to respect three new conditions ... [more ▼]

At the end of 2013, a new Common Agricultural Policy was defined at the European level, including the implementation of the so-called “green payment”, which obliges farmers to respect three new conditions in order to get financial support through direct payments. The year 2015 being the first implementation year, the consequences on Walloon agriculture are examined. It appears that 50% of Walloon farmers are not obliged to practice crop diversification, while 16% are obliged to have at least two crops on their arable land and 33% are obliged to have at least three crops on their arable land. Less than 1% does not respect the new diversification rules. Concerning the obligation to have at least 5% of ecological focus area on the arable land, it appears that 54% of Walloon farmers are in conditions not to be obliged to respect the measure. When they implement the measure, the percentage of ecological focus areas in arable land reaches 6.9% as a mean and 2.4% do not reach the requested 5%. Finally, it can be said that the green payment does not represent a big constraint for Walloon farmers, though eventual economic consequences are still to be precised, while environmental benefits are strengthened. [less ▲]

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See detailCalibration of MATSim in the context of natural hazards in Liège (Belgium): Preliminary results
Saadi, Ismaïl ULg; El Saeid Mustafa, Ahmed Mohamed ULg; Teller, Jacques ULg et al

in Proceedings of the 12th Conference on Transport Engineering (2016)

In Belgium, river floods are among the most frequent natural disasters and they may cause important changes on travel demand. In this regard, we propose to set up a large scale scenario using MATSim for ... [more ▼]

In Belgium, river floods are among the most frequent natural disasters and they may cause important changes on travel demand. In this regard, we propose to set up a large scale scenario using MATSim for guarantying an accurate assessment of the river floods impact on the transportation systems. In terms of inputs, agent-based models require a base year population. In this context, a synthetic population with a respective set of attributes is generated as a key input. Afterwards, agents are assigned activity chains through an activity-based generation process. Finally, the synthetic population and the transportation network are integrated into the dynamic traffic assignment simulator, i.e. MATSim. With respect to data, households travel surveys are the main inputs for synthesizing the populations. Besides, a steady-state inundation map is integrated within MATSim for simulating river floods. To our knowledge, very few studies have focused on how river floods affect transportation systems. In this regard, this research will undoubtedly provide new insights in term of methodology and traffic pattern analysis under disruptions, especially with regard to spatial scale effects. The results indicate that at the municipality level, it is possible to capture the effects of disruptions on travel behavior. In this context, further disaggregation is needed in future studies for identifying to what extent results are sensitive to disaggregation. In addition, results also suggest that the target sub-population exposed to flood risk should be isolated from the rest of the travel demand to reach have more sensitive effects. [less ▲]

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See detailGeological evidence for Holocene earthquakes and tsunamis along the Nankai-Suruga Trough, Japan
Garett, Ed; Fujiwara, Osamu; Garrett, Philip et al

in Geophysical Research Abstracts (2016)

The Nankai-Suruga Trough, lying immediately south of Japan’s densely populated and highly industrialised southern coastline, generates devastating great earthquakes (magnitude > 8). Intense shaking ... [more ▼]

The Nankai-Suruga Trough, lying immediately south of Japan’s densely populated and highly industrialised southern coastline, generates devastating great earthquakes (magnitude > 8). Intense shaking, crustal deformation and tsunami generation accompany these ruptures. Forecasting the hazards associated with future earthquakes along this >700 km long fault requires a comprehensive understanding of past fault behaviour. While the region benefits from a long and detailed historical record, palaeoseismology has the potential to provide a longer-term perspective and additional insights. Here, we summarise the current state of knowledge regarding geological evidence for past earthquakes and tsunamis, incorporating literature originally published in both Japanese and English. This evidence comes from a wide variety of sources, including uplifted marine terraces and biota, marine and lacustrine turbidites, liquefaction features, subsided marshes and tsunami deposits in coastal lakes and lowlands. We enhance available results with new age modelling approaches. While publications describe proposed evidence from > 70 sites, only a limited number provide compelling, well-dated evidence. The best available records allow us to map the most likely rupture zones of eleven earthquakes occurring during the historical period. Our spatiotemporal compilation suggests the AD 1707 earthquake ruptured almost the full length of the subduction zone and that earthquakes in AD 1361 and 684 were predecessors of similar magnitude. Intervening earthquakes were of lesser magnitude, highlighting variability in rupture mode. Recurrence intervals for ruptures of the a single seismic segment range from less than 100 to more than 450 years during the historical period. Over longer timescales, palaeoseismic evidence suggests intervals ranging from 100 to 700 years. However, these figures reflect thresholds of evidence creation and preservation as well as genuine recurrence intervals. At present, we have not identified any geological data that support the occurrence earthquakes of larger magnitude than that experienced in AD 1707; however, few published studies seek to establish the relative magnitudes of different earthquake and tsunami events. Alongside the paucity of research designed to quantify the magnitude of past earthquakes, we emphasise a number of other issues, including alternative hypotheses for proposed palaeoseismic evidence, the lack of robust chronological frameworks and insufficient appreciation of changing thresholds of evidence creation and preservation over time. These key issues must be addressed by future research. [less ▲]

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See detailEnglish translation and cross-cultural adaptation of the SARQOL Questionnaire
Beaudart, Charlotte ULg; Edwards, M.; Dennisson, E. et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 58

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See detailGeomorphometric mapping of spatio-temporal changes in Plio-Quaternary uplift in the NW European Alpine foreland
Demoulin, Alain ULg; Bourdon, Hadrien

in Geophysical Research Abstracts (2016), 18

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See detailIdentification and characterization of volatile organic compounds active against barley pathogens
De Clerck, Caroline ULg; Kaddes, Amine ULg; Fiers, Marie et al

in Bulletin OILB/SROP = IOBC/WPRS Bulletin (2016), 117

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See detailPharmacokinetic (PK) effects and safety of olaparib in combination with tamoxifen, anastrozole or letrozole : Phase I study
Plummer, R.; Verheul, H.M.; Langenberg, M. et al

in Journal of Clinical Oncology (2016), 34

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See detailLast millennium gravity reworking processes in the western Gulf of Corinth: correlations with historical seismicity and indication of earthquake clusters
Beckers, Arnaud; Beck, Christian; Hubert, Aurelia ULg et al

in Geophysical Research Abstracts (2016), 18

The western tip of the Corinth Rift is considered as the most active within this major extensional structure, as evidenced by: seismicity, GPS kinematics, and INSAR data (Bernard et al., 2006). Within the ... [more ▼]

The western tip of the Corinth Rift is considered as the most active within this major extensional structure, as evidenced by: seismicity, GPS kinematics, and INSAR data (Bernard et al., 2006). Within the frame of a multidisciplinary project dedicated to seismic hazards assessment for this region, two offshore surveys - high resolution seismic reflection and gravity coring - were conducted in this area. They were dedicated to the Late Quaternary sedimentary fill as the latter was expected to record both long term deformation (Beckers et al., 2015) and sedimentary “events” related to major earthquakes and/or tsunamis. Seismic reflection imaging displays the time and geographical distributions of large submarine landslides (MTDs) during the last 100 kyr. Based on a morpho-sedimentary map and the active fault pattern, up to 2 m-long cores were selected to detect and characterise the possible impact of historical events. The chronological control is based on AMS 14C dating and four detailed 210Pb and 137Cs profiles. Sedimentation (components, sources, transport and settling mechanisms) was analysed through textural, chemical, and mineralogical parameters. Turbidites could be clearly separated from the hemipelagic deposits. Our attempt to correlate identified sedimentary “events” with historical data greatly benefited from a recently elaborated catalog (Albini et al., 2014) with precisely re-located epicentral areas. Cable breaks were also taken into account. Attenuation models (Papazachos & Papaioannou’s, 1997) were used to discuss paleo-intensities vs. distance form epicentral areas. From the whole set of cores, the following results may be underlined: - the correlations between cores from the different sites are not complete, including for a few neighbouring sites belonging to the same morpho-sedimentary unit; we relate these discrepancies to the complex bottom morphology and/or to bottom currents responsible for local erosion; - for several well-documented earthquakes and tsunamis, we could not find a clearly recorded sedimentary impact; - non earthquake-triggered MTDs (as the 1963 event) produced specific layers identical to the major earthquakes impacts. At the difference, for a few cores from the deep axial floor, several sandy or silty turbidites permit to establish correlations: i) between coring sites, ii) with earthquakes which stroke two different areas, respectively east and west of the concerned part of the Gulf. Furthermore, the sedimentary events show a particular time distribution for the last 600 yr: - two intervals with short recurrences: a recent one ( 1900 AD-Present or 1750 AD-Present) and an older one ( 1550 AD-1700 AD or 1450 AD-1800 AD); these time distributions differ from each coring site; - a long “quiet” period (150 to 200 yr). From these results, we tentatively consider this sedimentary record as an indicator of a migration of seismogenic faulting activity. Ref.: Albini, P., et al., 2014. Techn. Rep. I.N.G.V. Roma. Beckers, A., et al., 2015. Marine Geology, 360:55–69 Bernard, P., et al., 2006. Tectonophysics, 426:7-30. Papazachos, C., Papaioannou, C., 1997. Journal of Seismology, 1:181-201. [less ▲]

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See detailPhage therapy against antimicrobial resistance, design of the first clinical study Phagoburn.
Jault, Patrick; Gabard, Jérôme; Leclerc, Thomas et al

in Critical Care (2016), 20(Suppl 2), 109

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See detailImpact of Age and Treatment Group in Childhood High Hyperdiploid Low Risk B-Cell Acute Lymphoblastic Leukemia (ALL): Results of the CLG-EORTC 58951 Study
Clement, Laura; Suciu, Stefan; Luquet, Isabelle et al

in Blood (2016)

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See detailPrevalence of frailty among nursing home, according to different operational definitions
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; GILLAIN, Sophie ULg et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 69

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See detailInvestigation of sol-gel yttrium doped ZnO thin films: structural and optical properties
Ivanova, T; Harizanova, A; Koutzarova, T et al

in Journal of Physics: Conference Series (2016)

Nanostructured metal oxide films are extensively studied due to their numerous applications such as optoelectronic devices, sensors. In this work, we report the Y–Zn–O nanostructured films prepared by sol ... [more ▼]

Nanostructured metal oxide films are extensively studied due to their numerous applications such as optoelectronic devices, sensors. In this work, we report the Y–Zn–O nanostructured films prepared by sol-gel technology from sols with different concentration of yttrium precursor, followed by post-annealing treatment. The Y doped ZnO thin films have been deposited on Si and quartz substrates by spin coating method, then treated at températures ranging from 300-800°C. XRD analysis reveals modification of the film structure and phases in the doped ZnO films. [less ▲]

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See detailOptical characterization of Sol-Gel ZnO:Al thin films
Ivanova, T; Harizanova, A; Koutzarova, T et al

in Journal of Physics: Conference Series (2016), 700

This paper presents a sol-gel technological process for preparing thin films of ZnO and ZnO:Al. The effect of annealing treatments (500, 600, 700 and 800 oC) on their properties was studied. The ... [more ▼]

This paper presents a sol-gel technological process for preparing thin films of ZnO and ZnO:Al. The effect of annealing treatments (500, 600, 700 and 800 oC) on their properties was studied. The structural evolution with the temperature was investigated by using X-Ray diffraction (XRD). Fourier Transform Infrared (FTIR) and UV-VIS spectrophotometry were applied to characterizing the films’ vibrational and optical properties. The ZnO and ZnO:Al films possessed a polycrystalline structure. The films studied are highly transparent in the visible spectral range. The optical band gap values and the haze parameter were also determined. [less ▲]

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See detailVolumetric brain MRI measurements in a retrospective Belgian multi-centr MRI biomarker study in dementia - REMEMBER
Niemantsverdriet; Smeets, D.; Bastin, Christine ULg et al

in Acta Neurologica Belgica (2016)

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See detailSclérostine & insuffisance rénale: que nous apprennent les différents méthodes de dosage?
PAQUOT, Francois ULg; BOUQUEGNEAU, Antoine ULg; CAVALIER, Etienne ULg et al

in Néphrologie & Thérapeutique (2016), 12(5), 374

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See detailFramework for building integrated policies regarding forest risk management: Insights from Wallonia (Belgium)
Riguelle, Simon ULg

in Natural Resources and Bioeconomy Studies (2016), 41

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See detailAntonymic co-presence: overview of the syntactic patterns model
Steffens, Marie ULg

in Studies van de BKL - Travaux du CBL - Papers of the LSB (2016), 10

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See detailNumerical prediction of ductile failure in the blanking process by means of uncoupled and coupled phenomenological damage models
Canales Cardenas, Cristian ULg; Ponthot, Jean-Philippe ULg

in MATEC Web of Conferences (2016)

Fracture prediction in blanking has gained great attention due to increasing requirements of high-quality products. In this work, the predictive capabilities of different uncoupled and coupled damage ... [more ▼]

Fracture prediction in blanking has gained great attention due to increasing requirements of high-quality products. In this work, the predictive capabilities of different uncoupled and coupled damage models, recently implemented in a fully implicit homemade FE code, for blanking process are compared. Some advanced models considered here include damage sensitivity to both triaxiality and Lode angle in their formulation. The material characterization is based on the history of internal variables during loading, where different mechanical tests are considered. Finally, numerical and experimental results are compared for a wide range of different geometries of blanking. [less ▲]

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See detailRole of inflammatory- and growth factors in the pathophysiology of gestational diabetes-related complications in neonates
Guffins, Amandine; FARHAT, Nesrine ULg; GKIOUGKI, Evangelia ULg et al

in Belgian Journal of Paediatrics (2016), 18(1), 82

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See detailSofosbuvir + simeprevir +/-ribavirin treatment is efficient in genotype 4 chronic hepatitis C patients: results of a large international cohort.
Moreno, C; Derbala, M; Nguyen-Khac, E et al

in Hepatology (Baltimore, Md.) (2016), 64(1), 1990

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See detailIncidence of bone fractures after critical illness
ROUSSEAU, Anne-Françoise ULg; Michel, Laure ULg; Bawin, Maxime ULg et al

in Intensive Care Medicine Experimental (2016), 4(Suppl 1), 1131

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See detailThe impact of factors related to retirement on cognitive functioning
Grotz, Catherine ULg; Adam, Stéphane ULg; Matharan, Fanny et al

in International Psychogeriatrics (2016), 27(supplement S1), 45-69

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See detailTechnical diversity within the tanged-tool Gravettian: new results from Belgium
Touzé, Olivier ULg; Flas, Damien; Pesesse, Damien

in Quaternary International (2016), http://dx.doi.org/10.1016/j.quaint.2015.11.034

Located at the interface between the Paris and the Rhine Basins and the more northern territories of Europe, Belgium contains several Gravettian occupations, both open-air and in caves. The available ... [more ▼]

Located at the interface between the Paris and the Rhine Basins and the more northern territories of Europe, Belgium contains several Gravettian occupations, both open-air and in caves. The available documentation is unfortunately limited by the earliness of the excavations conducted at most sites. Stratified records in karstic context, primarily excavated in the 19th century, are particularly affected by this situation. The analysis of Gravettian lithic technological behaviours can, however, rely on two open air sites excavated in the late 20th century which provide more rigorous data: Maisières-Canal and Station de l'Hermitage. These two sites have been the focus of comparisons that highlight their similarities, both in terms of the lithic industry and location. In fact, the former stands out for the presence of tanged tools, a typological marker which is usually associated with the Early Gravettian of Western Europe. In this article, we present a new study that evidences the differences in the lithic technical systems represented at these sites. After a presentation of the most recent data, we consider the causes that may be responsible for such diversity, highlighting the possible role of the chronological factor, but also of the existence of an original technical tradition in north-western Europe during the appearance and development of the Gravettian. [less ▲]

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See detailPleading for a new DCB in the historical German deep facies of Sauerland near Stockum
Streel, Maurice ULg; Korn, Dieter

in Subcommission on Devonian Stratigraphy Newsletter (2016), 31

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See detailExergy analysis applied to performance of buildings in Europe
Sartor, Kevin ULg; Dewallef, Pierre ULg

in Proceedings (2016)

Energy performance of buildings generally assesses the energy consumption of buildings such as heating, domestic heat water, ventilation systems... However, this approach is based on the first law of ... [more ▼]

Energy performance of buildings generally assesses the energy consumption of buildings such as heating, domestic heat water, ventilation systems... However, this approach is based on the first law of thermodynamics and considers only the quantity of energy used without considering its “quality” and leads to a lack of information about the energy conversion processes. This is particularly true in the new low-energy buildings where sometimes high temperatures sources are used to meet low-temperature needs. The exergy analysis of a system, based on first and second thermodynamic laws, can be used to overcome this. In this work, it is proposed to compare the energy and the exergy consumption of several kinds of buildings to determine the best systems in terms of energy and exergy needs. The energy demand calculations are performed using the official software available in Belgium and some assumptions are implemented to consider the exergy approach. As exergy calculations require a reference state, some different climatic conditions are also investigated. Finally, some conclusions are discussed to rank the sources of energy and their related exergy losses. [less ▲]

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See detailPurpura thrombocytopénique idiopathique...idiopathique, vraiment?
LONGTON, Julie ULg; DRESSE, Marie-Françoise ULg; Florkin, Benoît et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2016), 18(1), 112

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See detailA Brief History of MPLS Usage in IPv6
Vanaubel, Yves ULg; Mérindol, Pascal; Pansiot, Jean-Jacques et al

in Lecture Notes in Computer Science (2016)

Recent researches have stated the fast deployment of IPv6. It has been demonstrated that IPv6 grows much faster, being so more and more adopted by both Internet service providers but also by servers and ... [more ▼]

Recent researches have stated the fast deployment of IPv6. It has been demonstrated that IPv6 grows much faster, being so more and more adopted by both Internet service providers but also by servers and end-hosts. In parallel, researches have been conducted to discover and assess the usage of MPLS tunnels. Indeed, recent developments in the ICMP protocol make certain categories of MPLS tunnels transparent to traceroute probing. However, these studies focus only on IPv4, where MPLS is strongly deployed. In this paper, we provide a first look at how MPLS is used under IPv6 networks using traceroute data collected by CAIDA. At first glance, we observe that the MPLS deployment and usage seem to greatly differ between IPv4 and IPv6, in particular in the way MPLS label stacks are used. While label stacks with at least two labels are marginal in IPv4 (and mostly correspond to a VPN usage), they are prevalent in IPv6. After a deeper analysis of the label stack typical content in IPv6, we show that such tunnels result from the use of 6PE. This is not really surprising since this mechanism was specifically designed to forward IPv6 traffic using MPLS tunnels through networks that are not fully IPv6 compliant. However, we show that it does not result from non dual-stack routers but rather from the absence of native IPv6 MPLS signaling protocols. Finally, we investigate a large Tier-1 network, Cogent, that stands out with an original set-up. [less ▲]

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See detailTrace metals in soft tissue of marine bivalve Noah's ark (Arca noao) from Bizerte lagoon (Northern Tunisia)
Ghribi, Feriel; Richir, Jonathan ULg; Boussafa, Dhouha et al

in Rapports et Procès Verbaux des Réunions - Commission Internationale pour l'Exploration Scientifique de la Mer Mediterranée (2016), 41

This study aimed to monitor the bioaccumulation of 5 trace elements (TEs: Zn, Fe, Cu, Cd, and Pb) in the soft tissue of the Ark shell (Arca noae), seasonally sampled in Bizerte lagoon, northern Tunisia ... [more ▼]

This study aimed to monitor the bioaccumulation of 5 trace elements (TEs: Zn, Fe, Cu, Cd, and Pb) in the soft tissue of the Ark shell (Arca noae), seasonally sampled in Bizerte lagoon, northern Tunisia, in order to assess the nutritional quality of this bivalve and to promote its consumption as marine resource in Tunisia. The levels of all trace metals analyzed in Arca noae are below maximum admissible level which makes this species a healthy and safe food for human consumption. [less ▲]

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See detailUpdating the correlation Miospores/Conodonts in upper and uppermost Famennian
Streel, Maurice ULg

in IUGS, Subcommisson Devonian Strata Newsletter (2016), 31

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See detailA no-go theorem for the dark matter interpretation of the positron anomaly
Laletin, Maxim ULg

in Frascati Physics Series (2016), LXIII

The overabundance of high-energy cosmic positrons, observed by PAMELA and AMS-02, can be considered as the consequence of dark matter decays or annihilations. We show that recent FERMI/LAT measurements of ... [more ▼]

The overabundance of high-energy cosmic positrons, observed by PAMELA and AMS-02, can be considered as the consequence of dark matter decays or annihilations. We show that recent FERMI/LAT measurements of the isotropic diffuse gamma-ray background impose severe constraints on dark matter explanations and make them practically inconsistent. [less ▲]

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See detailGERONTECHNOLY IN WALLONIA
PETERMANS, Jean ULg; LEJEUNE, CHRISTOPHE; MAERTENS, Fulvie ULg et al

in Gerontechnology (2016), 15

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See detailPulsations in hot subdwarf stars: recent advances and prospects for testing stellar physics
Charpinet, Stéphane; Van Grootel, Valérie ULg; Fontaine, G. et al

in Proceedings of the International Astronomical Union (2016), 29

The evolved, core helium burning, extreme horizontal branch stars (also known as hot B subdwarfs) host several classes of pulsators showing either p- or g-modes, or both. They offer particularly favorable ... [more ▼]

The evolved, core helium burning, extreme horizontal branch stars (also known as hot B subdwarfs) host several classes of pulsators showing either p- or g-modes, or both. They offer particularly favorable conditions for probing with asteroseismology their internal structure, thus constituting arguably the most interesting seismic window for this intermediate stage of stellar evolution. G-modes in particular have the power to probe deep inside these stars, down to the convective He-burning core boundary where uncertain physics (convection, overshooting, semi-convection) is at work. Space data recently obtained with CoRoT and Kepler are offering us the possibility to probe these regions in detail and possibly shed new light on how these processes shape the core structure. In this short paper, we present the most recent advances that have taken place in this field and we provide hints of the foreseen future achievements of hot subdwarf asteroseismology. [less ▲]

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See detailRandomized, Double-Blinded, Controlled Clinical Trial Evaluating the Efficacy of a Diet Supplemented with Curcuminoids Extract, Hydrolysed Collagen and Green Tea Extract in Dogs with Osteoarthritis
Barthélémy, Nicolas; Comblain, Fanny ULg; Lesponne, Isabelle et al

in Veterinary and Comparative Orthopaedics and Traumatology (2016)

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See detailBlockade of Interleukin 27 Signaling Attenuates Graft Versus Host Disease By Augmenting CD4+ and CD8+ Regulatory T Cell Reconstitution
Belle, Ludovic ULg; Agle, K; Zhou, V et al

in Blood (2015, December), 126

The interleukin-6 (IL-6) cytokine superfamily (i.e. IL-6, IL-12, and IL-23) plays a major role in the modulation of inflammatory and regulatory pathways during graft versus host disease (GVHD). IL-27, a ... [more ▼]

The interleukin-6 (IL-6) cytokine superfamily (i.e. IL-6, IL-12, and IL-23) plays a major role in the modulation of inflammatory and regulatory pathways during graft versus host disease (GVHD). IL-27, a recently discovered member of this family, is a heterodimeric cytokine that is composed of the p28 and EBI3 subunits and signals through a heterodimeric receptor composed of WSX-1 and gp130. Notably, IL-6 also uses gp130 as a signaling component which biologically links IL-27 and IL-6. IL-27 has been shown to have opposing proinflammatory and immunoregulatory effects, but its role in GVHD is not well understood. To define the functional significance of IL-27, lethally irradiated Balb/c (H-2d) mice were transplanted with C57BL/6J (H-2b) BM and spleen cells, and then treated with an anti-IL-27p28-specific antibody on days 0 and +6. p28 antibody-treated animals had significantly improved weight recovery and overall survival (47% versus 0% survival at day 60, p=0.002), as well as reduced numbers of proinflammatory CD4+ and CD8+ IFN-γ+ T cells in GVHD target organs, when compared to isotype control antibody-treated mice. A similar outcome was observed in an MHC-matched, minor antigen disparate model (B6→Balb.B), indicating that this was not a strain-specific phenomenon. Given the similarities between IL-6 and IL-27, we examined whether blockade of IL-27 promoted regulatory T cell (Treg) reconstitution as has been observed with inhibition of IL-6 signaling. Recipients transplanted with BM grafts from B6 Foxp3EGFP reporter animals and treated with p28 antibody had a significant increase in the number of CD4+ nTregs, CD4+ iTregs and CD8+ iTregs in GVHD target organs, indicating that blockade of IL-27 augmented global Treg reconstitution. In fact, inhibition of IL-27 was more effective at augmenting Treg reconstitution than comparable antibody blockade of IL-6. To further elucidate the role of IL-27, we employed transgenic IL-27−/− and IL-27R−/− animals to dissect the relevant contributions of donor and recipient populations. Paradoxically, we observed that transplantation with IL-27−/− donor grafts exacerbated GVHD mortality and augmented accumulation of proinflammatory T cells, whereas transplantation of recipient IL-27−/− mice with wild type grafts had no effect on transplant outcomes. This discordance between antibody-based and genetic studies was unexpected and led us to consider whether there were steady state alterations in T cells from IL-27−/− animals that biased these cells towards a proinflammatory phenotype. To that end, we observed that naive CD8+ T cells from IL-27−/− mice had greater IFN-γ production than wild type cells after in vitro polyclonal stimulation and CD4+ nTregs from these animals had diminished expression of CXCR3 which is critical for Treg trafficking into inflamed tissue sites. Thus, the lack of endogenous IL-27 resulted in intrinsic immune dysregulation which led to an exacerbation of GVHD after transfer of these T cells into recipients. To resolve this paradox, we employed IL-27R−/− (WSX-1−/−) mice and demonstrated that mice transplanted with IL-27R−/− grafts had enhanced weight recovery and survival providing confirmation that blockade of IL-27 signaling reduced GVHD. In addition, using IL-27R−/− Foxp3EGFP reporter mice, we observed increased frequencies and numbers of CD4+ and CD8+ Foxp3+ T cells in mice reconstituted with IL-27R−/− grafts, confirming results observed with p28 antibody blockade. Since IL-10 is a mechanism by which CD4+ Tregs suppress GVHD and IL-27 has been shown to enhance T cell-derived IL-10 secretion in nontransplant models, we examined whether IL-27 blockade adversely affected IL-10 production by Tregs. Recipients transplanted with marrow grafts from IL-10.BitFoxp3EGFP dual reporter animals and treated with p28 antibody had a significant reduction in the frequency of IL-10-producing conventional CD4+ and CD8+ T cells in GVHD target organs. Notably, however, there was no difference in the frequency of CD4+ Foxp3+ IL-10+ T cells, indicating that blockade of IL-27 signaling preferentially affected conventional T cells and had no adverse effect on CD4+ Foxp3+ T cell-derived IL-10 production. In summary, these studies demonstrate that blockade of IL-27 signaling potently augments Treg reconstitution leading to a reduction in the severity of GVHD and may therefore represent a novel strategy to reduce mortality from this disease in man. [less ▲]

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See detailCroyances de la population générale au sujet des manipulations vertébrales
Demoulin, Christophe ULg; Baeri, D.; TOUSSAINT, Geoffrey ULg et al

in Revue du Rhumatisme (2015, December), 82S

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See detailAn Effective Approach for the Control of Uncertain Systems
Wanichanon, Thanapat; Cho, Hancheol ULg; Udwadia, Firdaus

in ABCM International Congress of Mechanical Engineering (2015, December)

This paper develops a new methodology for robust control of uncertain nonlinear systems. Two different controllers are developed and combined to accurately satisfy control requirements in the presence of ... [more ▼]

This paper develops a new methodology for robust control of uncertain nonlinear systems. Two different controllers are developed and combined to accurately satisfy control requirements in the presence of (a) system uncertainties in our knowledge of the exact physical system, and (b) uncertainties in the given forces acting on the system. The methodology is developed in two steps. First, a controller is designed for the nominal system, which is our best assessment of the actual physical system, and no uncertainties are considered at this step. This controller is realized using a recent finding in the field of analytical dynamics. The control requirements are recast as constraints on the dynamical system, and use of the analytical dynamics result enables us to find the required generalized forces to exactly satisfy the control requirements while simultaneously minimizing a control cost. The discrepancies caused by ignoring the uncertainties are next compensated for by adding a second controller that is obtained by generalizing the concept of sliding mode control. Unlike conventional sliding mode controllers, this additive controller does not suffer from a chattering problem; it also leads to much smaller errors, and faster response. In addition, it allows many different forms of control functions to be used, depending on practical considerations of implementation. A numerical example of a three-degree-of-freedom pendulum is simulated to demonstrate the control strategy developed herein, in which there are uncertainties both in the description of the physical system’s parameters and in the description of the gravity field acting on the pendulum. The example illustrates the accuracy, efficiency, and ease of implementation of the new control methodology. [less ▲]

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See detailQualités métrologiques de la version courte du Neurophysiology of Pain Questionnaire
Demoulin, Christophe ULg; Brasseur, P.; Roussel, N. et al

in Revue du Rhumatisme (2015, December), 82S

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See detailSpiral Arms in the Disk of HD 142527
Christiaens, Valentin ULg; Casassus, Simon; Pérez, Sebastian et al

in Astronomical Society of the Pacific Conference Series (2015, December), 499

In view of its large gap, previously reported asymmetries and near-infrared (NIR) spiral arms, the transition disk of the Herbig Fe star HD 142527 constitutes a remarkable case study. Based on our ALMA ... [more ▼]

In view of its large gap, previously reported asymmetries and near-infrared (NIR) spiral arms, the transition disk of the Herbig Fe star HD 142527 constitutes a remarkable case study. Based on our ALMA observations of the disk and previous NIR images, we try to infer the origin of the observed spirals. Different scenarios, including the effect of the binary companion, unseen planets, disk self-gravity and tidal interaction by a stellar encounter, are discussed in order to constrain the origin of the spirals. We conclude that at least a combination of two of the considered scenarios are required to account for the large annular gap, the NIR spirals and all three CO spirals. [less ▲]

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See detailEvaluation of simplified flexibility evaluation tools using a unit commitment model
Quoilin, Sylvain ULg; Nijs, Wouter; Hidalgo, Ignacio et al

in IEEE Digital Library (2015, December)

Different tools and methods have been proposed in the literature to assess the required flexibility resources and needs in a particular grid or geographical area. However, few of them are readily usable ... [more ▼]

Different tools and methods have been proposed in the literature to assess the required flexibility resources and needs in a particular grid or geographical area. However, few of them are readily usable in long term energy planning models because they require small time steps and detailed data. In this paper, two candidate methods to address the flexibility issues in such models are evaluated. A unit commitment model developed at the JRC, DispaSET 2.0, is used as a test case for the different simplified flexibility assessment tools. The modelled geographical area is Belgium, using historical data for the demand and VRE curves and their day-ahead forecast. Different VRE penetration scenarios are simulated to evaluate the flexibility of the power system. The simplified assessment tools are then run with the same inputs. Results indicate significant discrepancies between the detailed Unit Commitment model and the simplified tools. The underlying reasons are described and suggestions are formulated to improve their accuracy. [less ▲]

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See detailWho are my Visitors and Where do They Come From? An Analysis Based on Foursquare Check-ins and Place-based Semantics.
Hallot, Pierre ULg; Stewart, Kathleen; Billen, Roland ULg

in Eurographics Workshop on Urban Data Modelling and Visualisation 2015 (2015, November 23)

Activity recommendation systems aims at providing relevant information depending on targeted users' groups. For instance in a city, it makes sense to differentiate local residents from tourists. This ... [more ▼]

Activity recommendation systems aims at providing relevant information depending on targeted users' groups. For instance in a city, it makes sense to differentiate local residents from tourists. This research investigates to what extent the anonymized data collected from social networks can be used as a basis for making activity recommendations associated with local residents versus tourists when visiting a public place, such as a museum or gallery. Using rules based on the spatial, temporal and semantics of visited places, we are able to infer if a user is likely to be local or a tourist, based on anonymous sample Foursquare data and place-based semantics retrieved using Google Places API. Using semantics of visited places, it becomes possible to infer additional information about a user based on their movements over space and time. Depending on the kind and frequency of visited places, inferences about the aim of a visit to a location are possible. This analysis could provide information to users in the form of recommendations based on their movements while travelling around an area. This study has been performed using Foursquare check-ins for visitors to the Art Institute of Chicago between March 2010 and January 2011. [less ▲]

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See detailOutgassing and chemical evolution of C/2012 S1 (ISON)
Dello Russo, Neil; Vervack, Ronald J.; Kawakita, Hideyo et al

in Bulletin of the American Astronomical Society (2015, November 01), 47

Volatile production rates, relative abundances, rotational temperatures, and spatial distributions in the coma were measured in C/2012 S1 (ISON) using long-slit high-dispersion (λ/Δλ ~ 25,000) infrared ... [more ▼]

Volatile production rates, relative abundances, rotational temperatures, and spatial distributions in the coma were measured in C/2012 S1 (ISON) using long-slit high-dispersion (λ/Δλ ~ 25,000) infrared spectroscopy as part of a worldwide observing campaign. Spectra were obtained on UT 2013 October 26 and 28 with NIRSPEC at the W. M. Keck Observatory, and UT 2013 November 19 and 20 with CSHELL at the NASA IRTF. H[SUB]2[/SUB]O was detected on all dates, with production rates increasing by about a factor of 40 between October 26 (R[SUB]h[/SUB] = 1.12 AU) and November 20 (R[SUB]h[/SUB] = 0.43 AU). Short-term variability of H[SUB]2[/SUB]O was also seen as the production rate increased by nearly a factor of two during observations obtained over a period of about six hours on November 19. C[SUB]2[/SUB]H[SUB]6[/SUB], CH[SUB]3[/SUB]OH and CH[SUB]4[/SUB] abundances were slightly depleted relative to H[SUB]2[/SUB]O in ISON compared to mean values for comets measured at infrared wavelengths. On the November dates, C[SUB]2[/SUB]H[SUB]2[/SUB], HCN and OCS abundances relative to H[SUB]2[/SUB]O appear to be close to the range of mean values, whereas H[SUB]2[/SUB]CO and NH[SUB]3[/SUB] were significantly enhanced. We will compare derived chemical abundances in ISON to other comets measured with infrared spectroscopy. [less ▲]

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See detailFive years of comet narrow band photometry and imaging with TRAPPIST
Opitom, Cyrielle ULg; Jehin, Emmanuel ULg; Manfroid, Jean ULg et al

in Bulletin of the American Astronomical Society (2015, November 01), 47

TRAPPIST is a 60-cm robotic telescope in La Silla Observatory [1] mainly dedicated to the study of exoplanets and comets. The telescope is equipped with a set of narrow band cometary filters designed by ... [more ▼]

TRAPPIST is a 60-cm robotic telescope in La Silla Observatory [1] mainly dedicated to the study of exoplanets and comets. The telescope is equipped with a set of narrow band cometary filters designed by the NASA for the Hale-Bopp observing campaign [2]. Since its installation in 2010, we gathered a high quality and homogeneous data set of more than 30 bright comets observed with narrow band filters. Some comets were only observed for a few days but others have been observed weekly during several months on both sides of perihelion. From the images, we derived OH, NH, CN, C[SUB]2[/SUB], and C[SUB]3[/SUB] production rates using a Haser [3] model in addition to the Afρ parameter as a proxy for the dust production. We computed production rates ratios and the dust color for each comet to study their composition and followed the evolution of these ratios and colors with the heliocentric distance.The TRAPPIST data set, rich of more than 10000 images obtained and reduced in an homogeneous way, allows us to address several fundamental questions such as the pristine or evolutionary origin of composition differences among comets. The evolution of comet activity with the heliocentric distance, the differences between species, and from comet to comet, will be discussed. Finally, the first results about the one year campaign on comet C/2013 US10 (Catalina) and our recent work on the re-determination of Haser scalelengths will be presented.[1] Jehin et al., The Messenger, 145, 2-6, 2011[2] Farnham et al., Icarus, 147, 180-204, 2000[3] Haser, Bulletin de l’Académie Royal des Sciences de Belgique,63, 739, 1957 [less ▲]

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See detailPluto's atmosphere from stellar occultations in 2012 and 2013
Dias-Oliveira, Alex; Sicardy, Bruno; Lellouch, Emmanuel et al

in Bulletin of the American Astronomical Society (2015, November 01), 47

We present results from two Pluto stellar occultations observed on 18 July 2012 and 04 May 2013, and monitored respectively from five and six sites in South America. Both campaigns involved large ... [more ▼]

We present results from two Pluto stellar occultations observed on 18 July 2012 and 04 May 2013, and monitored respectively from five and six sites in South America. Both campaigns involved large telescopes (including the 8.2-m VLT at ESO/Paranal). The high SNR ratios and multi-chord coverage provide amoung the best Pluto atmospheric profiles ever obtained from the ground.We show that a spherically symmetric, clear (no-haze) and pure N2 atmosphere with a unique temperature profile satisfactorily fits the twelve lightcurves provided by the two events. We find, however, a small but significant increase of pressure of 6% (6-sigma level) between the two dates, with values of 2.16 ± 0.2 and 2.30 ± 0.01 μbar at the reference radius 1275 km, respectively.We provide atmospheric constrains between 1190 km and 1450 km from Pluto's center, and we determine the temperature profile with accuracy of a few km in vertical scale. Our model shows a stratosphere with strong positive gradient between 1190 km (at 36 K, 11 μbar) and r =1215 km (6.0 μbar), where a temperature maximum of 110 K is reached. Above it is a mesosphere with negative thermal gradient of -0.2 K/km up to 1,390 km (0.25 μbar), at which point, the mesosphere connects itself to a more isothermal upper branch at 81 K. This profile provides (assuming no troposphere) a Pluto surface radius of 1190 ± 5 km, consistent with preliminary values obtained by New Horizons. Currently measured CO abundances are too low to explain the negative mesospheric thermal gradient. We explore the possibility of an HCN (recently detected by ALMA) cooling. This model, however, requires largely supersaturated HCN. Zonal winds and vertical compositional variations of the atmosphere are also unable to explain the observed mesospheric trend.These events are the last useful ground-based occultations recorded before the 29 June 2015 occultation observed from Australia and New Zealand, and before the NASA's New Horizons flyby of July 2015. This work can serve as a benchmark in the New Horizons context, enabling comparisons between ground-based and space results concerning Pluto's atmospheric structure and temporal evolution. [less ▲]

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See detailChariklo's size, shape and orientation from stellar occultations
Bérard, Diane; Sicardy, Bruno; Assafin, Marcelo et al

in Bulletin of the American Astronomical Society (2015, November 01), 47

Chariklo is the largest Centaur object known to date, and it is surrounded by dense and narrow rings (Braga-Ribas et al. Nature 508, 72, 2014). The size, shape and orientation of the central body are ... [more ▼]

Chariklo is the largest Centaur object known to date, and it is surrounded by dense and narrow rings (Braga-Ribas et al. Nature 508, 72, 2014). The size, shape and orientation of the central body are important parameters to better understand the dynamics of the rings.In that context, we have analyzed three stellar occultations by Chariklo and its main ring observed on June 3, 2013, April 29, 2014 and June 28, 2014. Elliptical limb fitting to Chariklo’s main body occultation chords has been performed, where we denote a (resp. b) the semi-major (resp. semi-minor) axis of the limb. Preliminary results indicate that Chariklo’s limb is elliptical with axes ratio b/a~0.89. We obtain a~133 km and b~119 km, providing an equivalent radius of R[SUB]equiv[/SUB]=√(ab)~126 km. The rms dispersion of the fit, about 4 km, is compatible with local topographic features on a small icy body. For comparison, an equivalent radius of R[SUB]equiv[/SUB]= 119±5 km, based on thermal data, is given by Fornasier et al, AA 518, L11, 2014, while Duffard et al. AA 568, A79, 2014 estimate a= 122 km and b= 117 km.Our results are obtained under the simplifying assumption that the main ring is circular and that its center coincides with that of Chariklo. Caveats and error bars will be discussed, and dynamical implications will be presented. In particular, rough estimations of the ring apsidal precession rates will be given, as well as constraints on Chariklo's density. [less ▲]

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See detailNitrogen Isotopic Ratios in Cometary NH2: Implication for 15N-fractionation in Ammonia
Shinnaka, Yoshiharu; Kawakita, Hideyo; Jehin, Emmanuel ULg et al

in Bulletin of the American Astronomical Society (2015, November 01), 47

Isotopic ratios in cometary molecules are diagnostic for the physico-chemical conditions where molecules formed and are processed, from the interstellar medium to the solar nebula. Usually temperatures at ... [more ▼]

Isotopic ratios in cometary molecules are diagnostic for the physico-chemical conditions where molecules formed and are processed, from the interstellar medium to the solar nebula. Usually temperatures at the molecular formation control the fractionation of the heavier element in molecular species, e.g., D-fractionation in water.In cometary volatiles, the [SUP]14[/SUP]N/[SUP]15[/SUP]N ratios in CN have been well observed (Manfroid et al. 2009, A&A, 503, 613, and reference therein) and is consistent with the ratio in HCN (a most probable parent of CN) measured in few comets (Bockelée-Morvan et al. 2008, ApJ, 679, L49). Those ratios are enriched compared to the proto-solar value by a factor of ~3. In contrast to those Nitriles, there are only few reports on [SUP]14[/SUP]N/[SUP]15[/SUP]N ratios in Ammonia (as Amine) (Rousselot et al. 2014, ApJ, 780, L17; Shinnaka et al. 2014, ApJ, 782, L16). Ammonia (NH[SUB]3[/SUB]) is usually the most abundant and HCN is the second most abundant N-bearing volatiles in cometary ice. Especially, recent observations of [SUP]15[/SUP]NH[SUB]2[/SUB] revealed the [SUP]14[/SUP]N/[SUP]15[/SUP]N ratios in NH[SUB]3[/SUB] are comparable to those of CN. However, from the viewpoint of theoretical work, the enrichment of [SUP]15[/SUP]N in cometary NH[SUB]3[/SUB] cannot be reproduced by current chemical network models. Information about the diversity of the [SUP]14[/SUP]N/[SUP]15[/SUP]N ratios in NH[SUB]3[/SUB] of individual comets is needed to understand the formation mechanisms/environments of NH[SUB]3[/SUB] in the early solar system.To clarify the diversity of the [SUP]14[/SUP]N/[SUP]15[/SUP]N ratios in cometary NH[SUB]3[/SUB], we determine the [SUP]14[/SUP]N/[SUP]15[/SUP]N ratios in NH[SUB]3[/SUB] for more than ten comets individually which include not only Oort cloud comets but also short period comets by using the high-resolution optical spectra of NH[SUB]2[/SUB]. These spectra were obtained with both the UVES mounted on the VLT in Chile and the HDS on the Subaru Telescope in Hawaii.The derived [SUP]14[/SUP]N/[SUP]15[/SUP]N ratios in NH[SUB]3[/SUB] for more than ten comets show high [SUP]15[/SUP]N-enrichment compared with the elemental abundances of nitrogen in the Sun by about factor of ~3 and has no large diversity depending on these dynamical properties. We discuss about the origin of the formation conditions of cometary NH[SUB]3[/SUB] and its physico-chemical evolution in the solar nebula based on our and other results.This work was supported by JSPS, 15J10864 (Y. Shinnaka). [less ▲]

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See detailReport on the ground-based observation campaign of 67P/Churyumov-Gerasimenko
Jehin, Emmanuel ULg

in Bulletin of the American Astronomical Society (2015, November 01), 47

Rosetta gets closer to the nucleus than any previous mission, and returns wonderfully detailed measurements from the heart of the comet, but at the cost of not seeing the large scale coma and tails. The ... [more ▼]

Rosetta gets closer to the nucleus than any previous mission, and returns wonderfully detailed measurements from the heart of the comet, but at the cost of not seeing the large scale coma and tails. The ground-based campaign fills in the missing part of the picture, studying the comet at about 1000 km resolution, and following how the overall activity of the comet varies. These data provide context information for Rosetta, so changes in the inner coma seen by the spacecraft can be correlated with the phenomena observable in comets. This will not only help to complete our understanding of the activity of 67P, but also to allow us to compare it with other comets that are only observed from the ground.The ground-based campaign includes observations with nearly all major facilities world-wide. In 2014 the majority of data came from the ESO VLT, as the comet was still relatively faint and in Southern skies, but as it returns to visibility from Earth in 2015 it is considerably brighter, approaching its perihelion in August, and at Northern declinations. I will present results from the 2014 campaign, including visible wavelength photometry and spectroscopy, and the latest results from 2015 observations. [less ▲]

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See detailInfusion of third-party mesenchymal stream cells after liver transplantation: a phase-1, open-label, clinical study
DETRY, Olivier ULg; VANDERMEULEN, Morgan ULg; DELBOUILLE, Marie-Hélène ULg et al

in Transplant International (2015, November), 28(S4), 1027

Background: Mesenchymal stromal cells (MSC) are multipotent bone mar- row progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed ... [more ▼]

Background: Mesenchymal stromal cells (MSC) are multipotent bone mar- row progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. Methods: 10 liver transplant recipients under standard immunosuppression (TAC-MMF-low dose steroids until day 30) received 1.5–3 9 106/kg third party MSC on post-operative day 3 ` 2. These patients were prospectively compared to a group of 10 control liver recipients. Primary endpoints were MSC infusion toxicity, and incidence of cancer and opportunistic infections at month 6. Secondary endpoints were patient and graft survivals and rejection at month 6, as well as the effects of MSC on recipients’ immune function and on immunohistology of at month 6 graft biopsies. Results: No MSC infusional toxicity was observed. Both groups were comparable in terms of donor and recipient characteristics. There was no difference in primary end-points between control and MSC groups. No patient developed de novo cancer. There was no statistical difference in patient and graft survivals or in rejection rates. There was no graft rejection in the MSC group. Month-6 graft biopsies were not different according to Banff and fibrosis scores. Discussion: This phase 1 study showed excellent tolerability and safety of a single infusion of third-party MSC after liver transplantation. There were no graft safety issues and no excess of immunosuppression after MSC injection. Further analyses of consequences of MSC injection on the immune profile are needed. The possibility of avoiding calcineurin-inhibitors with repeated MSC injections as main immunosuppressive therapy and/of tolerance induction by MSC infusion should be investigated by further studies. This study is in part supported by an ESOT Senior Clinical Research Grant and by the University of Liege. [less ▲]

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See detailA consecutive series of 100 controlled DCD liver transplantation
DETRY, Olivier ULg; DE ROOVER, Arnaud ULg; Ledinh, H et al

in Transplant International (2015, November), 28(S4), 109296

Introduction: Donation after circulatory death (DCD) have been proposed to partially overcome the organ donor shortage. DCD-LT remains controversial, with reported increased risk of graft loss and ... [more ▼]

Introduction: Donation after circulatory death (DCD) have been proposed to partially overcome the organ donor shortage. DCD-LT remains controversial, with reported increased risk of graft loss and retransplantation. The authors retrospectively reviewed a single centre experience with controlled DCD-LT in a 12-year period. Patients and Methods: 100 DCD-LT were consecutively performed between 2003 and 2014. All donation and procurement procedures were performed as controlled DCD in operative rooms. Data are presented as median (ranges). Median donor age was 57 years (16–83). Median DRI was 2.16 (1.4–3.4). Most grafts were flushed with HTK solution. Allocation was centre-based. Median recipient MELD score at LT was 15 (7–40). Mean follow-up was 35 months. No patient was lost to follow-up. Results: Median total DCD warm ischemia was 19 min (10–39). Median cold ischemia was 235 min (113–576). Median peak AST was 1132 U/l (282– 21 928). Median peak bilirubin was 28 mg/dL. Patient survivals were 90.7%, 75.5% and 70.7% at 1.3 and 5 years, respectively. Graft survivals were 88.7%, 72.1% and 67.1% at 1.3 and 5 years, respectively. Biliary complications included mainly anastomotic strictures and extrahepatic main bile duct ischemic obstruction, that were managed either by endoscopy or hepatico- jejunostomy. No PNF or graft loss due to ischemic cholangiopathy was observed in this series. Discussion: In this series, DCD LT appears to provide results similar to classical LT. Short cold ischemia and recipient selection with low MELD score may be the keys to good results in DCD LT, in terms of graft survival and avoidance of ischemic cholangiopathy. If symptomatic ischemic cholangiopa- thy is diagnosed, adequate management with endoscopy and surgical hepaticojejunostomy may avoid graft loss and retransplantation. [less ▲]

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See detailPourcentage de femmes atteignant des T-scores de DMO non ostéoporotiques au rachis lombaire (RL) et à la hanche totale (HT) après 8 ans de traitement par denosumab (DMAb)
Ferrari, S.; Libanati, C.; Lin, J. et al

in Revue du Rhumatisme (2015, November), 82(S1), 35-36

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