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See detailUPLC®-MS/MS, an analytical tool for the accurate and rapid quantification of phytoestrogen metabolites in milk
Daems, Frédéric ULg; Jasselette, Christophe; Romnee, Jean-Michel et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2015, April 17), 19(2), 121-122

The term ‘phytoestrogen’ is used to define a wide variety of nonsteroidal compounds that occur naturally in many plants. When they are absorbed by cows, these polyphenolic compounds undergo ... [more ▼]

The term ‘phytoestrogen’ is used to define a wide variety of nonsteroidal compounds that occur naturally in many plants. When they are absorbed by cows, these polyphenolic compounds undergo biotransformation by specific bacteria present in the gastrointestinal tract. The resulting metabolites are absorbed in the organism and some are excreted in milk. The impact of these compounds on human health divides opinion. Some scientists believe that they might have adverse health effects. Others believe the opposite, especially with regard to their microbial metabolites, such as equol. Whatever one's view on the subject, scientists need accurate, sensitive and rapid analytical methods in order to continue the research on clarifying the phytoestrogen issue. Cow's milk is an animal product that is common in the human diet, and it is therefore important to evaluate its content of phytoestrogen metabolites. In order to study the human intake of equol via commercial milk, an analytical method was developed and validated following EMA/CVMP/VICH/463202/2009 guidelines. Enzymatic hydrolysis was used to release the equol. It was then extracted using double liquid/liquid extraction and analyzed using UPLC®-MS/MS, with an analysis runtime of only 5 min. This analytical method produced a linear calibration curve with a high correlation coefficient (R2≥0.996) between 5 and 1,000 ng mL−1. Good intra- and inter-day precision (RSDs≤5.3% and ≤5.2%, respectively) and accuracy (bias≤8.6%) were achieved. The recovery rate differed slightly among the different types of milk, ranging between 60.6±1.09% and 82.3±5.21%. Good method repeatability was observed (RSDs<15%). There was neither a matrix effect nor a carry-over effect, and the sample extracts were stable during storage for at least 7 days at −21°C and 5°C. In order to apply the proposed method and obtain an initial estimate of equol concentration in cow’s milk in Belgium, 44 samples of various brands found in several supermarkets and 5 raw milk samples from Walloon farms were analyzed. Equol was found in all the samples analyzed, with a concentration ranging from 10 to 50 ng mL−1 for conventional milk and from 70 to 130 ng mL−1 for organic milk. These results were compared with other European studies and the same trend was observed. The results obtained show the specificity, sensitivity and precision of this method for analyzing oestrogenic metabolite-equol in cow’s milk. This study should be extended to include a greater number of samples and be implemented over a longer period to see if there is a correlation between livestock practice and/or sample origins with the equol content in milk. The addition of other phytoestrogen compounds with this method, using UPLC®-MS/MS technology, could also lead to more reliable monitoring of these compounds in dairy production. [less ▲]

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See detailRetrieval of ammonia from ground-based FTIR measurements and its use for validation of satellite observations by IASI
Dammers, E; Palm, M; Warneke, T et al

in Geophysical Research Abstracts (2015, April 13), 17

Atmospheric Ammonia (NH3) has a major impact on human health and ecosystem services and plays a major role in the formation of aerosols [Erisman et al.,2013; Paulot and Jacob 2014]. NH3 concentrations are ... [more ▼]

Atmospheric Ammonia (NH3) has a major impact on human health and ecosystem services and plays a major role in the formation of aerosols [Erisman et al.,2013; Paulot and Jacob 2014]. NH3 concentrations are highly variable in space and time with overall short lifetime due to deposition and aerosol formation. The global atmospheric budget of nitrogen and in turn NH3 is still uncertain which asks for more ground-based and satellite observations around the world. Recent papers have described the possibility to measure NH3 with satellite infrared sounders which open up the way for calculations of global and regional nitrogen budgets [Clarisse et al 2009,Van Damme et al 2014a]. Validation of the satellite observations is essential to determine the uncertainty in the signal and its potential use. So far available surface layer observations of atmospheric NH3 concentrations have been used for comparisons with total columns retrieved from satellite observations [Van Damme 2014b]. We developed a retrieval for NH3 column density concentrations (molecules NH3/cm2) by fitting a set of spectral windows to ground-based solar absorption Fourier transform infrared (FTIR) measurements with the spectral fitting program SFIT4 [Hase et al., 2004]. The retrieval is then applied to FTIR measurements from a set of spectrometer sites from the Network for detection of Atmospheric Composition Change (NDACC) to retrieve NH3 columns for the sites located in Bremen, Germany; Lauder, New Zealand; Jungfraujoch, Switzerland; and the island of Reunion, France. Using eight years (2005-2013) of retrieved NH3 columns clear seasonal cycles are observed for each of the stations. Maximum concentrations can be related to NH3 emission sources, specific for the regions. A comparison between the retrieved NH3 columns and observations from the recent IASI- NH3 product [Van Damme et al, 2014a] using strict spatial and temporal criteria for the selection of observations showed a good correlation (R=0.82; slope=0.63). The IASI- NH3 columns for the Bremen and Lauder area show similar temporal cycles when compared to the FTIR observations. [less ▲]

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See detailHalogenated source gases measured by FTIR at the Jungfraujoch station: updated trends and new target species
Mahieu, Emmanuel ULg; Bader, Whitney ULg; Bovy, Benoît ULg et al

in Geophysical Research Abstracts (2015, April 13), 17

In this contribution, we present decadal time series of halogenated source gases monitored at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl) with Fourier Transform Infared (FTIR ... [more ▼]

In this contribution, we present decadal time series of halogenated source gases monitored at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl) with Fourier Transform Infared (FTIR) spectrometers, within the framework of the Network for the Detection of Atmospheric Composition Change. Total column trends presented in previous studies for CFC-11, -12 and HCFC-22, CCl4, HCFC-142b, CF4 and SF6 will be updated using the latest available Jungfraujoch solar observations. Investigations dealing with the definition of approaches to retrieve additional halogenated source gases from FTIR spectra will also be evoked. Our trend results will be critically discussed and compared with measurements performed in the northern hemisphere by the in situ networks. [less ▲]

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See detailBaseline Fibulin3 concentrations are associated with incidence of clinical knee OA after 30 months in overweight and obese women
Runhaar, Jos; Sanchez, Christelle ULg; Henrotin, Yves ULg et al

in Osteoarthritis and Cartilage (2015, April), 23(S2), 83

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See detailWolff’s Law and the Interplay between Bone Structure and External Loading
Ruffoni, Davide ULg; Christen, Patrik; Scherf, Heike et al

in IBMS BoneKEy (2015, April), 13

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See detailMeasuring and modelling the intra-day variability of the CO2 & CO2 vertical soil profile production in a Scots pine forest
Longdoz, Bernard; Goffin, Stéphanie; Parent, Florian et al

in Geophysical Research Abstracts (2015, April), 17

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See detailFacteurs génétiques et risque de dysglycémie dans des familles de diabétiques de type 2: l’étude DESCENDANCE
Franc, S; Cauchi, S; Yengo, L et al

in Diabètes & Métabolism (2015, April), 41(s1), 10-35

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See detailBiogenic Volatile Organic Compound (BVOC) emissions from agricultural crop species: is guttation a possible source for methanol emissions following light/dark transition?
Mozaffar, Ahsan ULg; Amelynck, Crist; Bachy, Aurélie ULg et al

in Geophysical Research Abstracts (2015, April), 17(EGU2015-2110-1),

In the framework of the CROSTVOC (CROp STress VOC) project, the exchange of biogenic volatile organic compounds (BVOCs) between two important agricultural crop species, maize and winter wheat, and the ... [more ▼]

In the framework of the CROSTVOC (CROp STress VOC) project, the exchange of biogenic volatile organic compounds (BVOCs) between two important agricultural crop species, maize and winter wheat, and the atmosphere has recently been measured during an entire growing season by using the eddy covariance technique. Because of the co-variation of BVOC emission drivers in field conditions, laboratory studies were initiated in an environmental chamber in order to disentangle the responses of the emissions to variations of the individual environmental parameters (such as PPFD and temperature) and to diverse abiotic stress factors. Young plants were enclosed in transparent all-Teflon dynamic enclosures (cuvettes) through which BVOC-free and RH-controlled air was sent. BVOC enriched air was subsequently sampled from the plant cuvettes and an empty cuvette (background) and analyzed for BVOCs in a high sensitivity Proton-Transfer Reaction Mass Spectrometer (hs-PTR-MS) and for CO2 in a LI-7000 non-dispersive IR gas analyzer. Emissions were monitored at constant temperature (25 °C) and at a stepwise varying PPFD pattern (0-650 µmol m-2 s-1). For maize plants, sudden light/dark transitions at the end of the photoperiod were accompanied by prompt and considerable increases in methanol (m/z 33) and water vapor (m/z 39) emissions. Moreover, guttation droplets appeared on the sides and the tips of the leaves within a few minutes after light/dark transition. Therefore the assumption has been raised that methanol is also coming out with guttation fluid from the leaves. Consequently, guttation fluid was collected from young maize and wheat plants, injected in an empty enclosure and sampled by PTR-MS. Methanol and a large number of other compounds were observed from guttation fluid. Recent studies have shown that guttation from agricultural crops frequently occurs in field conditions. Further research is required to find out the source strength of methanol emissions by this guttation phenomenon in real environmental conditions. [less ▲]

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See detailGAIMS: a tool specifically developed for the clinical gait analysis of patients with multiple sclerosis
Pierard, Sébastien ULg; Phan-Ba, Rémy; Giet, Amaury et al

in Multiple Sclerosis Journal (2015, April), 21(4), 498-499

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See detailThe CROSTVOC project – an integrated approach to study the effect of stress on BVOC exchange between agricultural crops and grassland ecosystems and the atmosphere
Amelynck, Crist; Heinesch, Bernard ULg; Aubinet, Marc ULg et al

in Geophysical Research Abstracts (2015, April), 17

Global changes in atmospheric composition and climate are expected to affect BVOC exchange between terrestrial vegetation and the atmosphere through changes in the drivers of constitutive BVOC emissions ... [more ▼]

Global changes in atmospheric composition and climate are expected to affect BVOC exchange between terrestrial vegetation and the atmosphere through changes in the drivers of constitutive BVOC emissions and by increases in frequency and intensity of biotic or abiotic stress episodes. Indeed, several studies indicate changes in the emission patterns of constitutive BVOCs and emission of stress-induced BVOCs following heat, drought and oxidative stress, amongst others. Relating changes in BVOC emissions to the occurrence of one or multiple stressors in natural environmental conditions is not straightforward and only few field studies have dealt with it, especially for agricultural crop and grassland ecosystems. The CROSTVOC project aims to contribute in filling this knowledge gap in three ways. Firstly, it aims at performing long-term BVOC emission field measurements from maize (Zea mays L.) and wheat (Triticum aestivum L.), two important crop species on the global scale, and from grassland. This should lead to a better characterization of (mainly oxygenated) BVOC emissions from these understudied ecosystems, allowing a better representation of those emissions in air quality and atmospheric chemistry and transport models. BVOC fluxes are obtained by the Disjunct Eddy Covariance by mass scanning (DEC-MS) technique, using a hs-PTR-MS instrument for BVOC analysis. Secondly, the eddy covariance BVOC flux measurements (especially at the grassland site) will be accompanied by ozone flux, chlorophyll fluorescence, photosynthesis and soil moisture measurements, amongst others, to allow linking alterations in BVOC emissions to stress episodes. Simultaneously, automated dynamic enclosures will be deployed in order to detect specific abiotic and biotic stress markers by PTR-MS and identify them unambiguously by GC-MS. Thirdly, the field measurements will be accompanied by laboratory BVOC flux measurements in an environmental chamber in order to better disentangle the responses of the BVOC emissions to driving factors that co-occur in field conditions and to determine the influence of single abiotic stressors on BVOC emissions. Next to a general presentation, some preliminary results of the project will be shown. [less ▲]

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See detailIndividual variation of gait characteristics along a 500 meter walk in people with multiple sclerosis and healthy volunteers
Phan-Ba, Rémy; Pierard, Sébastien ULg; Giet, Amaury et al

in Multiple Sclerosis Journal (2015, April), 21(4), 532-533

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See detailModelling carbon fluxes of forest and grassland ecosystems in Western Europe using the CARAIB dynamic vegetation model: evaluation against eddy covariance data.
Henrot, Alexandra-Jane ULg; François, Louis ULg; Dury, Marie ULg et al

in Geophysical Research Abstracts (2015, April), 17

Eddy covariance measurements are an essential resource to understand how ecosystem carbon fluxes react in response to climate change, and to help to evaluate and validate the performance of land surface ... [more ▼]

Eddy covariance measurements are an essential resource to understand how ecosystem carbon fluxes react in response to climate change, and to help to evaluate and validate the performance of land surface and vegetation models at regional and global scale. In the framework of the MASC project (« Modelling and Assessing Surface Change impacts on Belgian and Western European climate »), vegetation dynamics and carbon fluxes of forest and grassland ecosystems simulated by the CARAIB dynamic vegetation model (Dury et al., iForest - Biogeosciences and Forestry, 4:82-99, 2011) are evaluated and validated by comparison of the model predictions with eddy covariance data. Here carbon fluxes (e.g. net ecosystem exchange (NEE), gross primary productivity (GPP), and ecosystem respiration (RECO)) and evapotranspiration (ET) simulated with the CARAIB model are compared with the fluxes measured at several eddy covariance flux tower sites in Belgium and Western Europe, chosen from the FLUXNET global network (http://fluxnet.ornl.gov/). CARAIB is forced either with surface atmospheric variables derived from the global CRU climatology, or with in situ meteorological data. Several tree (e.g. Pinus sylvestris, Fagus sylvatica, Picea abies) and grass species (e.g. Poaceae, Asteraceae) are simulated, depending on the species encountered on the studied sites. The aim of our work is to assess the model ability to reproduce the daily, seasonal and interannual variablility of carbon fluxes and the carbon dynamics of forest and grassland ecosystems in Belgium and Western Europe. [less ▲]

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See detailAssessment of damage and anisotropic plasticity models to predict Ti-6Al-4V behavior
Guzmán Inostroza, Carlos Felipe ULg; Tuninetti, Víctor; Gilles, Gaëtan ULg et al

in Key Engineering Materials [=KEM] (2015, April), 651-653

The plastic behavior of the Ti-6Al-4V alloy includes several features as strength differential effect, anisotropy and yield strength sensitivity to temperature and strain rate. Monotonic tensions in the ... [more ▼]

The plastic behavior of the Ti-6Al-4V alloy includes several features as strength differential effect, anisotropy and yield strength sensitivity to temperature and strain rate. Monotonic tensions in the three orthogonal directions of the material are performed to identify the Hill ’48 yield criterion. Monotonic compression and plane strain tensile tests are also included in the experimental campaign to identify the orthotropic yield criterion of CPB06. An assessment of the two models is done by comparing the yield loci and the experimental data points for different levels of plastic work. A first approach of the damage modelling of the Ti-6AL-4V alloy is investigated with an extended Gurson-Tvergaard-Needleman damage model based on Hill ’48 yield criterion. Finite element simulations of the experiments are performed and numerical results allows checking force-displacement curves until rupture and local information like displacement and strain fields. The prediction ability of the Hill ’48, CPB and extended Gurson models are assessed on simple shear and notched tensile tests until fracture. [less ▲]

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See detailImproving energy partitioning and the nighttime energy balance by implementation of a multi-layer energy budget in ORCHIDEE-CAN
Chen, Yiying; Ryder, James; Naudts, Kim et al

in Geophysical Research Abstracts (2015, April), 17

Canopy structure is one of the most important vegetation characteristics for land-atmosphere interactions as it determines the energy and scalar exchanges between land surface and overlay air mass. In ... [more ▼]

Canopy structure is one of the most important vegetation characteristics for land-atmosphere interactions as it determines the energy and scalar exchanges between land surface and overlay air mass. In this study we evaluated the performance of a newly developed multi-layer energy budget (Ryder et al., 2014) in a land surface model, ORCHIDEE-CAN (Naudts et al., 2014), which simulates canopy structure and can be coupled to an atmospheric model using an implicit procedure. Furthermore, a vertical discrete drag parametrization scheme was also incorporated into this model, in order to obtain a better description of the sub-canopy wind profile simulation. Site level datasets, including the top-of-the-canopy and sub-canopy observations made available from eight flux observation sites, were collected in order to conduct this evaluation. The geo-location of the collected observation sites crossed climate zones from temperate to boreal and the vegetation types included deciduous, evergreen broad leaved and evergreen needle leaved forest with maximum LAI ranging from 2.1 to 7.0. First, we used long-term top-of-the-canopy measurements to analyze the performance of the current one-layer energy budget in ORCHIDEE-CAN. Three major processes were identified for improvement through the implementation of a multi-layer energy budget: 1) night time radiation balance, 2) energy partitioning during winter and 3) prediction of the ground heat flux. Short-term sub-canopy observations were used to calibrate the parameters in sub-canopy radiation, turbulence and resistances modules with an automatic tuning process following the maximum gradient of the user-defined objective function. The multi-layer model is able to capture the dynamic of sub-canopy turbulence, temperature and energy fluxes with imposed LAI profile and optimized parameter set at a site level calibration. The simulation result shows the improvement both on the nighttime energy balance and energy partitioning during winter and presents a better Taylor skill score, compared to the result from single layer simulation. The importance of using the multi-layer energy budget in a land surface model for coupling to the atmospheric model will also be discussed in this presentation. [less ▲]

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See detailDiurnal and seasonal variability of CO2 fluxes over a degraded Woodland under a Sudanian climate in Northern Benin (West Africa)
Ago, Expédit Evariste ULg; Serça, Dominique; Agbossou, Euloge Kossi et al

in Geophysical Research Abstracts (2015, April), 17

Turbulent CO2 exchanges over a degraded woodland were measured during 17 months (from November 2005 to March 2007) by an eddy-covariance system at Nangatchori in the northern part of Benin, West Africa ... [more ▼]

Turbulent CO2 exchanges over a degraded woodland were measured during 17 months (from November 2005 to March 2007) by an eddy-covariance system at Nangatchori in the northern part of Benin, West Africa. The site (Lat 9.65°N, Long 1.74°E, Alt: 432 m), under a Sudanian climate, is one of the sites that were equipped in the framework of the international AMMA-CATH program. The site was highly disturbed during preceding years by illegal tree logging, agricultural activities, cattle pasture, and bushfire. The footprint area is mainly formed by herbs and crops with some sparse shrubs and trees. Fluxes data were completed during the same period by meteorological measurements made at the Nalohou site located approximately 20 km from Nangatchori, and by an inventory of dominating species on 1km2 area around the tower during the wet season. Fluxes response to climatic variables was analyzed. The annual drought and moisture cycle was found to be the main controlling factor of the ecosystem dynamics. A very clear response of CO2 fluxes to PPFD appears, but is different according to seasons. During wet season, CO2 uptake increases with increasing PPFD following a typical curvilinear function and saturates for high PPFD (PPFD > 1000 µmol m-2 s-1), while during dry season, a very weak linear response of CO2 fluxes was observed. No clear dependency of the total ecosystem respiration on temperature was observed. At an annual scale (from November 1st 2005 to October 31st 2006), net carbon sequestered by the ecosystem was 18 +- 5 g C m-2. Finally, with respect to the water use the ecosystem appeared to be more efficient during morning and wet season than during afternoon and dry period. [less ▲]

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See detailUltra-low power microsystems integrated
Laurent, Philippe ULg; Dupont, François ULg; Stoukatch, Serguei ULg et al

in Conference proceedings (2015, March 11)

Microsys has developed wireless microsystems using off-the-shelf components comprising ultra-low power sensors such as temperature, humidity and luminosity. We will show how to make the microsystem more ... [more ▼]

Microsys has developed wireless microsystems using off-the-shelf components comprising ultra-low power sensors such as temperature, humidity and luminosity. We will show how to make the microsystem more compact by decreasing the power consumption. So doing, no or little maintenance is required, leading to an efficient Wireless Sensor Network (WSN). [less ▲]

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See detailRole of adamalysin proteases in modulations of tumor microenvironment and premetastatic niches
Donati, Kim ULg; Bekaert, Sandrine; Sepult, Christelle ULg et al

in Revue des Maladies Respiratoires (2015, March), 32

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See detailMulticenter Belgian experience of sofosbuvir (medical need program) in very difficult-to-treat HCV patients: safety and efficacy results.
Degre, D; Laleman, W; Verhelst, X et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 03

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See detailImpact of intensive enteral nutrition in association with corticosteroïds in the treatment of severe alcoholic hepatitis: a multicenter randomized controlled trial
Moreno, C; Trepo, E; Louvet, A et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 01

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See detailDesign and implementation of a ‘physical activity day’ for overweight and obese youth
Cloes, Marc ULg; DEWANDRE, Anne-Cécile ULg; LEBRETHON, Marie-Christine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1),

This study aimed to analyze the development and implementation of an adapted physical activity day expected to underline to overweight/obese youth the role of PA and hw they could be more active in their ... [more ▼]

This study aimed to analyze the development and implementation of an adapted physical activity day expected to underline to overweight/obese youth the role of PA and hw they could be more active in their daily life. [less ▲]

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See detailInfusion of third-party mesenchymal stream cells after liver transplantation: a phase-1, open-label, clinical study
DETRY, Olivier ULg; VANDERMEULEN, Morgan ULg; DELBOUILLE, Marie-Hélène ULg et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 29

Background: Mesenchymal stromal cells (MSC) are multipotent bone marrow progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed ... [more ▼]

Background: Mesenchymal stromal cells (MSC) are multipotent bone marrow progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. Patients & Methods: Clinical grade MSCs were locally collected from the bone marrow of unrelated healthy donors. They were cultured in a GMP-compliant lab, underwent extensive quality controls and were frozen for storage in a MSC bank. When needed for patient treatment, MSC were thawed and intravenously injected into patients. 10 liver transplant recipients under standard immunosuppression (TAC-MMF-low dose steroids until day 30) received 1.5-3x106/kg MSC on post-operative day 3±2. These patients were prospectively compared to a group of 10 control (MSC-) liver recipients. Primary endpoints were MSC infusion toxicity, and incidence of cancer and opportunistic infections at month 6. Secondary endpoints were patient and graft survivals and rejection at month 6, as well as the effects of MSC on recipients’ immune function and on immunohistology of at month 6 graft biopsies. Results: No MSC infusional toxicity was observed. Both groups were comparable in terms of donor and recipient characteristics. There was no difference in primary end-points between control and MSC groups. No patient developed de novo cancer. There was no statistical difference in patient and graft survivals or in rejection rates. There was no graft rejection in the MSC group. Month-6 graft biopsies were not different according to Banff and fibrosis scores. Discussion: This phase 1 study showed excellent tolerability and safety of a single infusion of third-party MSC after liver transplantation. There were no graft safety issues and no excess of immunosuppression after MSC injection. Further analyses of consequences of MSC injection on the immune profile are needed. The possibility of avoiding calcineurin-inhibitors with repeated MSC injections as main immunosuppressive therapy and/of tolerance induction by MSC infusion should be investigated by further studies. [less ▲]

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See detailDairy products & Bone Health: Turning facts and beliefs into clinical practice
Bruyère, Olivier ULg

in Osteoporosis International (2015, March), 26(S1), 383

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See detailMultitasking abilities in persons diagnosed with schizophrenia: a new tool and cognitive model.
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Laroi, Frank ULg

in Schizophrenia Bulletin (2015, March), 41(Supplement 1),

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities (Semkovska et al., 2010). Multitasking refers to ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities (Semkovska et al., 2010). Multitasking refers to activities (e.g. preparing a meal) where the person has to: (a) carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; (b) define the tasks’ targets; (c) and where the person is faced with unexpected problems during the realization of these tasks (Burgess, 2000). However, the cognitive underpinnings of multitasking abilities have never been adequately explored in schizophrenia. Further, only two cognitive models exist in the literature, which are based on student (Logie et al., 2011) and neurological (Burgess et al., 2000) samples. Both of these models suggest three primary constructs: Memory, Planning and Intent. There are, however, several limitations related to the way multitasking abilities were evaluated in these studies. We thus developed a computerized real-life activity task - the Computerized Meeting Preparation Task (CPMT), which was specifically designed to take into account the multitasking nature of certain everyday life activities. Using this task, and based on previous studies (Burgess et al., 2000; Logie et al., 2011), the aim of the present study was to evaluate multitasking abilities in schizophrenia and to do so in a new cognitive model of multitasking that takes into account certain cognitive functions that are not integrated in existing models. Methods: Fifty-seven individuals with schizophrenia and 41 matched healthy controls completed the CMPT. Participants were also evaluated with a battery of cognitive tests. Results: The results suggest that the CMPT possesses good sensitivity and confirmed the three underlying constructs of multitasking (Memory, Planning and Intent), which were found to be underpinned by several cognitive functions and multitasking aspects. Conclusion: Taken together, this new cognitive model and the CMPT could be a good basis for cognitive interventions of multitasking abilities in schizophrenia. Burgess, P.W., 2000. Strategy application disorder: the role of the frontal lobes in human multitasking. Psychol Res 63, 279-288. Logie, R., et al., 2011. Multitasking: multiple, domain-specific cognitive functions in a virtual environment. Mem Cogn 39, 1561-1574. Semkovska, M. et al., 2004. Assessment of executive dysfunction during activities of daily living in schizophrenia. Schizophr Res 69, 289-300. [less ▲]

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See detailEvaluation de l’efficacité de la simulation haute fidélité dans la prise en charge des troubles du rythme cardiaque chez l’enfant: étude pilote
SCHUMACHER, Katharina ULg; Seghaye, Marie-Christine ULg; Baugnon, Thomas et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1),

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See detailExploring limiting factors in the prediction of allogeneic HSCT related mortality: an in-silico machine learning analysis of the acute leukemia working party (ALWP) registry of the EBMT
SHOUVAL, R.; LABOPIN, M.; UNGER, R. et al

in Bone Marrow Transplantation (2015, March), 50

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See detailAnalyse rétrospective des données concernant les patientes avec diabète gestationnel au CHU de Liège
RADERMECKER, Régis ULg; PHILIPS, Jean-Christophe ULg; Sepulchre, E

in Diabètes & Métabolism (2015, March), 41

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See detailPhysical rehabilitation in musculoskeletal conditions: which method?
Bruyère, Olivier ULg

in Osteoporosis International (2015, March), 26(S1), 68

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See detailExpel: a novel non-destructive method for mining soluble tumor biomarkers
Costanza, B; Blomme, A; MUTIJIMA NZARAMBA, Eugène ULg et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 13

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See detailAvancement du projet de l'inventaire typologique et dendrochronologique des charpentes anciennes en région Bruxelles-Capitale
Weitz, Armelle ULg; Charruadas, Paulo ULg; Crémer, Sarah et al

in Archaeologia Mediaevalis (2015, March), 38

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See detailMetabolomic, proteomic and preclinical imaging of patient-derived tumor xenografts for improving treatment of liver metastases patients
Perez Palacios, A; Blomme, A; Boutry, S et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 134

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See detailRemboursement de la mesure continue du glucose en Belgique: un exemple de multidisciplinarité
RADERMECKER, Régis ULg; Contessi, El

in Diabètes & Métabolism (2015, March), 41

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See detailLes PPP comme nouveau mode de régulation du marché de l'accompagnement des demandeurs d'emploi. A chaque modèle de partenariat son type de stratégie
Remy, Céline ULg

in Cahiers Loyola (2015, February), 1

Cette communication vise à montrer en quoi les partenariats publics-privés (PPP) constituent désormais un nouveau mode de régulation du marché de l’accompagnement des demandeurs d’emploi. Les services ... [more ▼]

Cette communication vise à montrer en quoi les partenariats publics-privés (PPP) constituent désormais un nouveau mode de régulation du marché de l’accompagnement des demandeurs d’emploi. Les services publics de l’emploi (SPE) doivent établir des PPP avec des prestataires de service pour la mise en place de formation à destination des demandeurs d’emploi. La réalisation de trois études de cas au sein des SPE, dont deux en Belgique et une en Suisse, nous permet de mettre en évidence une forte influence du modèle de gestion du PPP sur la collaboration entre les parties-prenantes mais aussi sur les stratégies développées par les prestataires pour surmonter les problèmes liés à la collaboration avec l’Office de l’Emploi et à la mise en place de la prestation de service. [less ▲]

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See detailAzione, testualizzazione, notazione
Dondero, Maria Giulia ULg

in Espressione e contenuto. Rivista on-line dell'AISS Associazione Italiana di Studi Semiotici (2015, February), 18/19

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See detailCastalia — A Mission to a Main Belt Comet
Jones, G. H.; Altwegg, K.; Bertini, I. et al

in LPI (2015, January 01), 1829

Main Belt Comets (MBCs) are a newly identified class of solar system object, having asteroid-like orbits but sometimes exhibiting comet-like behavior. We present the case for a mission to an MBC, to be ... [more ▼]

Main Belt Comets (MBCs) are a newly identified class of solar system object, having asteroid-like orbits but sometimes exhibiting comet-like behavior. We present the case for a mission to an MBC, to be submitted to the European Space Agency. [less ▲]

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See detailMassive stars: privileged sources of cosmic-rays for interstellar astrochemistry
De Becker, Michaël ULg

in Bulletin de la Société Royale des Sciences de Liège (2015, January), 84

Massive stars can be considered as crucial engines for interstellar physics. They are indeed the main providers of UV radiation field, and constitute a substantial source of chemical enrichment. On their ... [more ▼]

Massive stars can be considered as crucial engines for interstellar physics. They are indeed the main providers of UV radiation field, and constitute a substantial source of chemical enrichment. On their evolution time-scale (at most about 10 Myr), they typically stay close to their formation site, i.e. close to molecular clouds very rich in interstellar molecules. These stellar objects have also the property to be involved in particle acceleration processes leading to the production of high energy charged particles (cosmic-rays). After rejection in the interstellar medium, these particles will play a substantial role in processes such as those simulated in various facilities dedicated to experimental astrochemistry. This short contribution intends to put these particles, crucial for astrochemistry, in their adequate astrophysical context. [less ▲]

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See detailPaucisymptomatic presentation of viral myocarditis in children
TSHIMANGA, Prisca ULg; DARON, B.; FARHAT, Nesrine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 98

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See detailRespiratory distress or eating disorder could: it be a vascular ring ?
Solowianiuk, Marie ULg; FARHAT, Nesrine ULg; HOLZKI, Josef ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 98

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See detailSexually dimorphic effect of gestational exposure to BPA on DNA methylation in the rat placenta
Fudvoye, Julie ULg; Dehan, Pierre ULg; Trooskens, G. et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 37

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See detailMono- and Biallelic deletion of neurexin - à propos of 3 cases
Barrea, Christophe ULg; RAMAEKERS, Vincent ULg; Seghaye, Marie-Christine ULg

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 107

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See detailAutoimmune thyroid diseases in early childhood three case reports
Guffins, Amandine ULg; HARVENGT, Julie ULg; LUYCKX, F. et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 41

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See detailCellulite faciale sévère au départ d'une lésion de varicelle - à propos d'un cas
Bourcy, Emilie ULg; Saliba, Mariane ULg; NYAMUGABO MUNYERE NKANA, Kindja ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 113

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See detailDoes gestational diabetes influence foetal organ function ?
Guffins, Amandine ULg; FARHAT, Nesrine ULg; GKIOUGKI, Evangelia ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 99

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See detailFood provioning influences ranging patterns in northern pigtailed macaques (Macaca leonina)
Huynen, Marie-Claude ULg; Savini, Tommaso ULg; Asensio, Norberto et al

in International Journal of Primatology (2015, January)

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See detailJAWAC evolving technologies to study sleep disturbance in obese adolescents - a preliminary study
Barrea, Christophe ULg; HARVENGT, Julie ULg; LEBRETHON, Marie-Christine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 107

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See detailComplications de l'appendicite aiguë chez l'enfant : à propos d'un cas
Janssen, Aurélie; NYAMUGABO MUNYERE NKANA, Kindja ULg; STERGIOPOULOU, Theodouli ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 66

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See detailExperimental astrochemistry: from ground-based to space-borne laboratories (Foreword)
De Becker, Michaël ULg; Cottin, Hervé; Fleury-Frenette, Karl ULg et al

in Bulletin de la Société Royale des Sciences de Liège (2015, January), 84(4-6),

The investigation of the origin and evolution of molecules in space environments, either in interstellar or interplanetary conditions, constitutes a topic of high importance in modern space sciences. The ... [more ▼]

The investigation of the origin and evolution of molecules in space environments, either in interstellar or interplanetary conditions, constitutes a topic of high importance in modern space sciences. The presence of diversified and complex molecules motivates astrochemists to explore their formation mechanisms along with the physical conditions ruling these physico-chemical processes. Beside theoretical approaches aiming at simulating these processes, experimental techniques are nowadays frequently applied. Both laboratory and space experiment projects allow to reproduce to some extent the adequate conditions to understand some of these processes. The most recent results based on these techniques, and the prospects for future investigations, including the use of space platforms, were the scientific motivation of this workshop. These proceedings summarize a part of the content of this workshop, including abundant references to the relevant bibliography. [less ▲]

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See detailPromotion of physical activity among children and adolescents followed for overweight or obesity in
DEWANDRE, Anne-Cécile ULg; HARVENGT, Julie ULg; LAGASSE, Celine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 40

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See detailGene expression of growth factors and apoptosis regulating proteins in rat myocardium after exposure to endocrine disrupting chemicals : a preliminary study
ROUATBI, Hatem ULg; GERARD, Arlette ULg; Seghaye, Marie-Christine ULg

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 99

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See detailUne gangrène digitale humide traitée de façon conservatrice
Janssen, Aurélie; STERGIOPOULOU, Theodouli ULg; NYAMUGABO MUNYERE NKANA, Kindja ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 64

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See detailExercice stress echocardiography in secondary mitral regurgitation : impact of pulmonary hypertension
MAGNE, Julien; PIERARD, Luc ULg; LANCELLOTTI, Patrizio ULg

in Archives of Cardiovascular Diseases (2015, January), 7

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See detailComparison of soil water potential sensors
Degré, Aurore ULg; Cadwell, Todd; van der Ploeg, Martine

in Geophysical Research Abstracts (2015)

Temporal and spatial monitoring of soil water potential and soil water content are necessary for quantifying water flow in the domains of hydrology, soil science and crop production as knowledge of the ... [more ▼]

Temporal and spatial monitoring of soil water potential and soil water content are necessary for quantifying water flow in the domains of hydrology, soil science and crop production as knowledge of the soil water retention curve is important for solving Richards’ equation. Numerous measurement techniques exist nowadays that use various physical properties of the soil-water complex to record changes in soil water content or soil water potential. Laboratory techniques are very useful to determine static properties of the soil water retention curve, and have been used to show the impacts of hysteresis. Yet, other spatiotemporal dynamics resulting from for example growing root systems, biological activity, periodic tillage and their impact on the soil structure cannot satisfactory be quantified in static setups in the laboratory. ). To be able to quantify the influence of soil heterogeneity, and spatiotemporal dynamics on the soil water retention curve, an in situ approach combining soil moisture and soil water potential measurements could provide useful data. Such an in situ approach would require sensors that can measure a representative part of the soil water retention curve. The volumetric soil water content is often measured using time domain reflectometry, and has gained widespread acceptance as a standard electronic means of volumetric water content measurement. To measure the soil water potential, water filled tensiometers are used in most studies. Unfortunately, their range remains limited due to cavitation. Recently, several new sensors for use under in situ conditions have been proposed to cover a wider range of pressure head: Polymer tensiometers, MPS (Decagon) and pF-meter (ecoTech). In this study, we present the principles behind each measurement technique. Then we present the results of a fully controlled experiment where we compared two MPS sensors, two pF-meter sensors and two POT sensors in the same repacked soil. It allows us to discuss advantages and disadvantages of each method. A CS616 volumetric water content probe was installed to compare in situ measured retention curves with laboratory measured retention curves for each method. [less ▲]

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See detailQuality of work life of rural emergency department nurses and physicians: a pilot study
Bragard, Isabelle ULg; Dupuis, Gilles; Archambault, Patrick et al

in Canadian Family Physician (2015), 61(Suppl 1), 9

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See detailTracheal diameter in puppies
Rizza, Maïlis ULg; Liotta, Annalisa Pia ULg; Billen, Frédéric ULg et al

in Veterinary Radiology & Ultrasound (2015)

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See detailEnquêter sur les non-publics de la culture: quelle posture de recherche pour quel dispositif méthodologique?
Ghebaur, Cosmina ULg

in Questions de Communication (2015)

Mes travaux portent sur les non-publics de la culture et leur fabrication institutionnelle, à savoir leur production par les institutions chargées de mettre en œuvre sur un territoire donné les politiques ... [more ▼]

Mes travaux portent sur les non-publics de la culture et leur fabrication institutionnelle, à savoir leur production par les institutions chargées de mettre en œuvre sur un territoire donné les politiques culturelles les concernant. Pour explorer cette question, je me place dans la perspective initiée en sociologie de l'art par Pascale Ancel et Alain Pessin (2004) et caractérisée par la remise en question de la frontière entre publics et non-publics. On peut, écrit Martine Azam (2004), être " à la fois " public et non-public s'agissant de deux objets culturels différents ou du même objet à des moments différents. L'objectif de cet article est d'expliciter les principaux choix méthodologiques que j'ai été amenée à faire en enquêtant, avec cette posture de recherche, sur une exposition photographique en extérieur organisée dans une ville de la banlieue parisienne. [less ▲]

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See detailBaseline characteristics of the Liège Hand Osteoarthritis Cohort (LIHOC)
NEUPREZ, Audrey ULg; Bruyère, Olivier ULg; Dardenne, Nadia ULg et al

in Annals of the Rheumatic Diseases (2015), 74(Supp2), 1346

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See detailImplémentation d’un cours avec simulation haute fidélité pour la préparation des internes débutant leur formation en pédiatrie et en médecine d’urgence
SCHUMACHER, Katharina ULg; Seghaye, Marie-Christine ULg; Solowianiuk, Marie et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1),

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See detailTechnical diversity within the tanged-tool Gravettian: new results from Belgium
Touzé, Olivier ULg; Flas, Damien; Pesesse, Damien

in Quaternary International (2015), http://dx.doi.org/10.1016/j.quaint.2015.11.034

Located at the interface between the Paris and the Rhine Basins and the more northern territories of Europe, Belgium contains several Gravettian occupations, both open-air and in caves. The available ... [more ▼]

Located at the interface between the Paris and the Rhine Basins and the more northern territories of Europe, Belgium contains several Gravettian occupations, both open-air and in caves. The available documentation is unfortunately limited by the earliness of the excavations conducted at most sites. Stratified records in karstic context, primarily excavated in the 19th century, are particularly affected by this situation. The analysis of Gravettian lithic technological behaviours can, however, rely on two open air sites excavated in the late 20th century which provide more rigorous data: Maisières-Canal and Station de l'Hermitage. These two sites have been the focus of comparisons that highlight their similarities, both in terms of the lithic industry and location. In fact, the former stands out for the presence of tanged tools, a typological marker which is usually associated with the Early Gravettian of Western Europe. In this article, we present a new study that evidences the differences in the lithic technical systems represented at these sites. After a presentation of the most recent data, we consider the causes that may be responsible for such diversity, highlighting the possible role of the chronological factor, but also of the existence of an original technical tradition in north-western Europe during the appearance and development of the Gravettian. [less ▲]

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See detailMonitoring the pregnancy status of dairy cows using mid-infrared spectra of milk collected from milk recording
Laine, Aurélie ULg; Dale, Laura-Monica ULg; Bel Mabrouk, Hana ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2015), 19(2), 97-124

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See detailThe position of Strontium ranelate in today's management of osteoporosis
Reginster, Jean-Yves ULg; Brandi, ML; Cannata-Andia, J et al

in Osteoporosis International (2015), 26(S1), 39

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See detailTypochronologie des charpentes de toiture en Bourgogne médiévale (France)
Blain, Sophie ULg; Hoffsummer, Patrick ULg; Aumard, Sylvain et al

in Chronique d’Archaeologia Mediaevalis (2015), 38

Localisée entre deux zones bien définies culturellement : l’Europe méditerranéenne et celle du Nord, et dotée d’un réseau hydrographique dense, la situation géostratégique de la Bourgogne favorise les ... [more ▼]

Localisée entre deux zones bien définies culturellement : l’Europe méditerranéenne et celle du Nord, et dotée d’un réseau hydrographique dense, la situation géostratégique de la Bourgogne favorise les échanges de matériaux, les déplacements humains, la circulation d'idées et de savoir-faire au sein de cette zone de passage et de contacts. Cette dynamique marque inévitablement la construction architecturale à l’époque médiévale. A partir du XIe siècle, des abbayes d'influence situées dans la région telles que Cluny et Cîteaux, essaiment à travers toute l'Europe. Ainsi, la région favorise l'affirmation de conventions architecturales qui sont en vigueur dans la Bourgogne romane, puis gothique. Inscrit dans le cadre d’un mandat de recherche postdoctorale financé par le F.R.S-FNRS (2013-2016), le projet présenté ici vise à établir les réseaux d'influences d'idées et de savoir-faire dans le domaine de la construction dans cette zone emblématique en évaluant les origines de modèles architecturaux et leur diffusion au sein de la région mais également à l’extérieur. [less ▲]

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See detailBiomarkers of prognosis and efficacy of treatment in OA
Henrotin, Yves ULg

in BMC Musculoskeletal Disorders (2015), 16(suppl 1),

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See detailBaseline Fibulin3 Concentrations Are Associated with Incidence of Clinical Knee OA after 30 Months in Overweight and Obese Women
Runhaar; Sanchez, Christelle ULg; Taralla, Sébastien et al

in Arthritis and Rheumatism (2015), 67(Suppl10),

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See detailPosterior Reversible Encephalopathy Syndrome in Pediatric Leukemia
Carichon, Tifenn ULg; Piette, Caroline ULg; Florkin, Benoît et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1), 48

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See detailErratum: Elevated basal levels of circulating activated platelets predict ICU-acquired sepsis and mortality: a prospective study.
Layios, N.; Delierneux, Céline ULg; Hego, A. et al

in Critical care (London, England) (2015), 19(1), 301

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See detailA randomized double-blind study of denosumab compared with zoledronic acid in postmenopausal women with osteoporosis previously treated with oral bisphosphonate.
MILLER, P.D.; PANNACCIULLI, N.; BROWN, J.P. et al

in Arthritis and Rheumatology (2015), 67(S10), 1181-1182

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See detailMuscle fatigue resistance and self-perceived fatigue in relation with sarcopenia and quality of life
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Bautmans, I et al

in Journal of Frailty & Aging (2015), 4(S1), 61-62

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See detailPrevalence of frailty in nursing home residents according to various diagnostic tools
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Dardenne, Nadia ULg et al

in Journal of Frailty & Aging (2015), 4(S1), 61

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See detailPercentage of women achieving non-osteoporotic BMD T-scores at the lumbar spine (LS) and total hip (TH) during up to 8 years of Denosumab (Dmab) treatment
Ferrari, S; Libanati, C; Lin, CJF et al

in Osteoporosis International (2015), 26(S1), 149-150

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See detailWIMUAS: A TOOL TO REVIEW WILDLIFE DATA FROM VARIOUS FLIGHT PLANS
Linchant, Julie ULg; Lhoest, Simon ULg; Quevauvillers, Samuel ULg et al

in International Archives of Photogrammetry, Remote Sensing and Spatial Information Sciences (2015), XL-3/W3

To get around UAS limitations and propose a viable solution for wildlife monitoring, the development of new inventory methods is needed. However, most authors use the classic systematic transect method as ... [more ▼]

To get around UAS limitations and propose a viable solution for wildlife monitoring, the development of new inventory methods is needed. However, most authors use the classic systematic transect method as data processing and statistics are easier. We thus created an application to process data from every type of flight plan and to help detect and compare observations on large datasets. WiMUAS is a small software compatible with the open-source QGIS© that allows the creation of visual maps compatible with geographical information systems based on telemetry data and payload parameters to estimate the covered area. The application also has a slider for animal detection that allows multiple observers to record and compare their results for accurate counts. We then tested it on data from a trial realized on savannah animal populations in Democratic Republic of Congo using the Falcon UAS. We created a new type of flight plan, a rosette-shaped design that can be covered in three flights,.and repeated it twice. More than 5000 images were collected during the six flights. Image projection gives an area of 12,4 km2 for the first trial and of 12,1 km2 for the second. The mean sampling rate for both test is 6,1 %. Observers spotted buffaloes, hippos, warthogs and various antelopes with different success over an average rate of 8 images reviewed per minute. Resulting densities observed by the three observers are similar for each test (coefficient of variation 6,9 and 8,6 % respectively) but mean densities vary a lot between the two trials (23,8 and 6,5 animals/km2 respectively). [less ▲]

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See detailLa Tregua de Doce Años (1609-1621): los confesores de los Archiduques, espiritualidad y política en los Países Bajos Católicos
Pirlet, Pierre-François ULg

in Libros de la corte (2015), 7

Iñigo de Brizuela and Andrés de Soto, both confessors of the Archdukes were key figures at Brussels' court. Each of them used to influence the policy, using different bias. But they weren't trying to ... [more ▼]

Iñigo de Brizuela and Andrés de Soto, both confessors of the Archdukes were key figures at Brussels' court. Each of them used to influence the policy, using different bias. But they weren't trying to reach similar goals: Brizuela carefully acted to preserve Spanish interests in the Catholic Netherlands, while de Soto struggled for a Catholic victory. Their political actions and its reasons will be covered by this paper. [less ▲]

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See detailRelations entre gain baro-réflexe et autres marqueurs de risque chez le patient diabétique de type 2
SCHEEN, André ULg; MARCHAND, Monique ULg; PHILIPS, Jean-Christophe ULg

in Annales de Cardiologie et d'Angeiologie (2015), 64(s1),

André J. Scheen, Monique Marchand, Jean-Christophe Philips (1) (1) Service de Diabétologie, Nutrition et Maladies métaboliques, CHU Sart Tilman, Université de Liège, Liège, Belgique. Relations entre gain ... [more ▼]

André J. Scheen, Monique Marchand, Jean-Christophe Philips (1) (1) Service de Diabétologie, Nutrition et Maladies métaboliques, CHU Sart Tilman, Université de Liège, Liège, Belgique. Relations entre gain baro-réflexe et autres marqueurs de risque chez le patient diabétique de type 2 Relationships between baroreflex gain and other risk markers in patients with type 2 diabetes Objectifs : Le gain baro-réflexe (GBR) est un marqueur de la neuropathie autonome cardiovasculaire (NAC) qui s’avère plus discriminant que le classique R-R E/I ratio. Le but du travail est d’étudier les relations entre le GBR et d’autres marqueurs de risque comme la pression pulsée (PP) et la diminution du débit de filtration glomérulaire (DFG) chez le patient diabétique de type 2 (DT2). Méthodes : Au total, 64 patients DT2 ont été étudiés par enregistrement continu de la pression artérielle (PA) et de la fréquence cardiaque (FC) lors d’un test postural standardisé (test de «squatting» : 1min debout – 1min accroupi – 1min debout). GBR est calculé par la pente de la relation entre les espaces R-R et PA systolique lors du redressement. PP (PAS-PAD) est analysée pendant tout le test et par son augmentation durant l’accroupissement (delta PP). Le DFG est calculé par la formule MDRD avant et après un suivi moyen de 12±5 années. Résultats : Les patients ont été séparés en deux groupes en fonction de la valeur médiane du GBR : G1 (n=34) : </=1,36 msec/mm Hg (moyenne ± SD : 0,77±0,40) vs G2 (n=30) : >1,36 (3,05±0,35). Les sujets de G1 sont légèrement plus âgés (58±7 vs 54±8 ans; p=0,04), mais ont un sexe ratio, une durée du DT2, un taux d’HbA1c et des valeurs de PA comparables aux valeurs de G2. Les patients de G1 ont une FC de base plus élevée (88±15 vs 82±14 bpm; p=0,0462) et un DFG plus bas (79±19 vs 95±19 ml/min; p=0,0479). Si la PP en position debout est comparable (59±15 vs 54±15 mmHg; p=0,1983), elle devient plus élevée en position accroupie (73±18 vs 65±16 mmHg; p=0,0395) chez G1 que chez G2. Lors du redressement, la chute de PA moyenne est significativement plus importante (-46±12 vs -38±12 mmHg; p=0,0079), avec un retard à la récupération des valeurs de base (29±19 vs 21±19 sec; p=0,0107) et une tachycardisation moindre (17±8 vs 23±9 bpm; p=0,0359) chez G1. Par contre, la diminution du DFG durant le suivi est comparable chez G1 vs G2 (-13±21 vs -13±21 ml/min; p=0,8561). Conclusion : Un GBR abaissé, marqueur de la NAC, est associé à une PP élevée en position accroupie (un marqueur indirect de rigidité artérielle) et une diminution du DFG. Par contre, la seule valeur de GBR ne permet pas de prédire l’ampleur de la dégradation de la fonction rénale lors d’un suivi ultérieur de 12 années [less ▲]

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See detailImplementation of geriatric assessment - based recommendations in older patients with cancer : a multicenter prospective study
Baitar, A; Kenis, C; Moor, R et al

in Journal of Geriatric Oncology (2015), 6

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See detailCan we use bone turnover markers as targets for antiresorptive treatment in postmenopausal osteoporosis ? an analysis from two phase 3 clinical trials.
BROWN, J.P.; DAKIN, P.; HADJI, P. et al

in Arthritis and Rheumatology (2015), 67(S10), 515-517

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See detailLa circulation du livre humaniste italien en Brabant au XVe siècle
Adam, Renaud ULg

in Publication du Centre Européen d'Etudes Bourguignonnes (2015), 55

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See detailGlucosamine and chondroitin salts in the management of osteoarthritis in Europe
Reginster, Jean-Yves ULg

in Osteoporosis International (2015), 26(S1), 60-61

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See detailCREATING PERENNIAL FLOWER STRIPS: THINK FUNCTIONAL!
Uyttenbroeck, Roel ULg; Hatt, Séverin ULg; Piqueray, Julien et al

in Agriculture and Agricultural Science Procedia (2015), 6

In last decades, farmland biodiversity came under large threat. To counteract farmland biodiversity loss and other environmental impacts of intensive agriculture, European farmers can apply Agri ... [more ▼]

In last decades, farmland biodiversity came under large threat. To counteract farmland biodiversity loss and other environmental impacts of intensive agriculture, European farmers can apply Agri-environmental schemes. One of these is the creation of flower strips, a part of the cropping field where flowers are sown or naturally settled. Flower strips are known to increase biodiversity in the agricultural landscape, notably attracting specific insects groups, such as pollinators and natural enemies that can provide valuable pollination and biocontrol services to the crop. However, the plant species composition and management of the strips can have a large influence on the identity and amount of useful insects present in the strips, suggesting the need to develop tailored flower strips to maximize the services delivered. Functional diversity (FD) is sometimes proposed as a promising approach, focusing on plant functional traits rather than plant species itself. Yet, it is not certain that sowing a set of plant species results in the desired vegetation with the desired functional trait composition. Species from soil seed bank or dispersing from neighboring vegetation can settle in the strip, while sown species might not always be equally adapted to local conditions. To test this, we developed seed mixtures with four different levels of FD, based on flower traits, and sew them as flower strips in a conventional arable field. We monitored the vegetation to calculate the FD of the realized vegetation. While the absolute FD values of the realized vegetation were lower than the expected FD values, the realized vegetation showed the same FD gradient as expected from the sown mixtures, indicating that it is possible to manipulate FD in flower strips. [less ▲]

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See detailPrevalence of frailty in nursing home residents according to various diagnostic tools
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Dardenne, Nadia ULg et al

in Osteoporosis International (2015), 26(S1), 160-161

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See detailTumeurs rhabdoïdes néonatales : à propos de deux cas.
Carichon, T; FORGET, Patricia ULg; Piette, Caroline ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1),

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See detailMaintenir la banque de proximité à l'heure du digital : des pressions du contexte aux jeux d'acteurs
Jarnias, Sylvie; Reydet, Sabine; Pichault, François ULg

in Actes du colloque de l'AGRH (2015)

Les banques françaises subissent depuis une dizaine d’années, de profonds changements qui les amènent à redéfinir leur approche client et les amènent à faire des choix stratégiques importants. Nous avons ... [more ▼]

Les banques françaises subissent depuis une dizaine d’années, de profonds changements qui les amènent à redéfinir leur approche client et les amènent à faire des choix stratégiques importants. Nous avons partagé l’expérience innovante d’une grande banque mutualiste française, qui a initié un important changement organisationnel dont la particularité est de s’inscrire dans une approche de type NWOW. L’intérêt de ce papier réside dans la mobilisation de deux approches théoriques complémentaires, la théorie néo-institutionnelle élargie, et l’approche stratégique des acteurs, pour analyser, dans une perspective critique (Critical Management Studies), l’implémentation d’un changement inspiré du NWOW. Nous avons mené une étude de cas auprès d’une soixantaine de collaborateurs bancaires impliqués dans le changement organisationnel. Nous avons recueilli l’avis des membres de la Direction Générale pour comprendre l’émergence et les caractéristiques du changement organisationnel, et celui des collaborateurs sur le terrain pour évaluer leurs perceptions quant aux conséquences du changement dans leur quotidien professionnel. [less ▲]

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See detailRecommendation for the management of knee osteoarthritis
Reginster, Jean-Yves ULg; Bruyère, Olivier ULg

in Bone, Muscle and Joint Diseases (2015), (S35), 40

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See detailAppel au peuple/appel du public : décrire la réception comme une "adresse"
Servais, Christine ULg

in Questions de Communication (2015), Série Actes 26

Par rapport à d'autres productions culturelles ou scientifiques, la particularité des médias de masse est qu'ils font quelque chose au peuple en faisant quelque chose du peuple, c'est-à-dire en le ... [more ▼]

Par rapport à d'autres productions culturelles ou scientifiques, la particularité des médias de masse est qu'ils font quelque chose au peuple en faisant quelque chose du peuple, c'est-à-dire en le représentant à lui-même. La construction mass-médiatique du "peuple" a donc une dimension pragmatique que les études de réception doivent intégrer. C'est à quoi s'attache cette communication, notamment à travers la notion d'adresse, issue du travail de J. Derrida, et celle de "partage du sensible" formalisée par Jacques Rancière. [less ▲]

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