References of "Paper published in a journal"
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See detailLevels of Dechloranes and PBDEs in Serum from Central European Population
Brasseur, Catherine ULg; Focant, Jean-François ULg

in Organohalogen Compounds (2013), 75

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See detailAnother Generalization of Abelian Equivalence: Binomial Complexity of Infinite Words
Rigo, Michel ULg; Salimov, Pavel ULg

in Lecture Notes in Computer Science (2013), 8079

The binomial coefficient of two words u and v is the number of times v occurs as a subsequence of u. Based on this classical notion, we introduce the m-binomial equivalence of two words refining the ... [more ▼]

The binomial coefficient of two words u and v is the number of times v occurs as a subsequence of u. Based on this classical notion, we introduce the m-binomial equivalence of two words refining the abelian equivalence. The m-binomial complexity of an infinite word x maps an integer n to the number of m-binomial equivalence classes of factors of length n occurring in x. We study the first properties of m-binomial equivalence. We compute the m-binomial complexity of the Sturmian words and of the Thue-Morse word. We also mention the possible avoidance of 2-binomial squares. [less ▲]

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See detailImaging osteoarthritis using (18F)FPRGD2 PET/CT : observation and potential application.
WITHOFS, Nadia ULg; ALVAREZ MIEZENTSEVA, Victoria ULg; SIMONI, Paolo ULg et al

in Journal of Nuclear Medicine (The) (2013), 54(SUPPL), 250

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See detailEstimation of the fascine efficiency in terms of runoff infiltration and sediments deposition
Degré, Aurore ULg; Pineux, Nathalie ULg; Cantreul, Vincent ULg et al

in Geophysical Research Abstracts (2013), 15

Runoff inundations and mudflows are more and more frequent phenomena. In 2011, Belgium had a lot of its municipalities affected by this problematic. Since then, mitigation measures are more and more set ... [more ▼]

Runoff inundations and mudflows are more and more frequent phenomena. In 2011, Belgium had a lot of its municipalities affected by this problematic. Since then, mitigation measures are more and more set up in agricultural watersheds. The fascines are one of these measures which allow to protect the public and private infrastructures and in the same way, which don’t reduce the famers productivity. They consist in branches faggots piled up between two rows of stakes. These linear constructions are mainly put in place across concentrated runoff axis in order to slow down the water and to filter the mud. Only few quantifications of their effectiveness (in terms of flow and concentration water reduction) exist and are however needed to better recommend these types of mitigation measures. Our experiment aims at measuring discharge and mud concentration reduction due to the fascines in a completely defined context. The tests were realised through fascines planted in field border. A watertight surface of 2,45m to 0,80m carries the water to the fascines. Three types of fascines were tested (willow wood fascine, straw fascine, straw compacted fascine), three different water flows were applied (0,5L/s, 3L/s and 6L/s) and three water concentration in dry soil (13g/L, 26g/L, 38g/L) were used. The different factor combinations were tested. The results show that we can expect a reduction of 60% of the flow for the biggest water flows (proportional efficiency with the water flow). The factor interaction study doesn’t allow to see a difference between the type. About the sediment water concentration, the filtration can reach 50%, the fascine with wood faggots showing a better efficiency. Finally, the difference between the fascine type show that straw fascine can support a biggest watershed (25 hectares) than the wood faggot fascine can (5-10 hectares) but during a smaller return period (one year against five years). [less ▲]

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See detailThe general approach to the patient with osteoarthritis : is a treatment algorithm feasible ?
Reginster, Jean-Yves ULg

in Osteoporosis International (2013), 24(1), 385

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See detailInitiation of methane turbulent flux measurements over a grazed grassland in Belgium
Dumortier, Pierre ULg; Aubinet, Marc ULg; Chopin, Henri ULg et al

in Geophysical Research Abstracts (2013), 15

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See detailEvaluation de l'exposition professionnelle aux cytostatiques des travailleurs de deux services du CHU de Liège
Rusu, Dorina; DUBOIS, Nathalie ULg; Surleraux, Cécile et al

in Acta Clinica Belgica (2013), 68(6), 472

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See detailInteraction of fengycin with stratum corneum mimicking model membranes: a calorimetry study
Nasir, Mehmet Nail ULg; Eeman, Marc; Olofsson, Gerd et al

in European Biophysics Journal [=EBJ] (2013), 42(S1), 168

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See detailPharmacological management : osteoporosis and osteoarthritis, similarities and differences
Reginster, Jean-Yves ULg

in Osteoporosis International (2013), 24(1), 75-76

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See detailBehavioural Ecology of Bonobos (Pan paniscus) in the Forest-Savannah Mosaics of Western Democratic Republic of Congo
Vimond, Marie; Serckx, Adeline ULg; Beudels-Jamar, Roseline et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013)

The long-term survival of the Endangered bonobo (IUCN, 2012) will depend on well thought out conservation programmes that need to be built both upon the species’ ecological requirements and local socio ... [more ▼]

The long-term survival of the Endangered bonobo (IUCN, 2012) will depend on well thought out conservation programmes that need to be built both upon the species’ ecological requirements and local socio-economics realities. Yet there is still a lot to find out, including information on the species geographical distribution. In 2005, the presence of a western population was confirmed in the forest-savannah mosaic in the south-western part of the Lake Tumba Landscape. With the exception of an early study carried out in Lukuru, the species is mainly known from lowland rainforest research sites in the Cuvette Centrale. The western forest-savannah mosaic is an ecotone with a marked seasonal pattern, a high variability of habitats and monthly variations in fruit production. All this leads to spatio-temporal variation of food availability. In order to increase studies and monitoring of this unique population, WWF initiated a habituation process of two groups of bonobos 6 years ago. The groups are now semi-habituated, making the collection of direct daily observations possible. Our objective is to describe the behavioural strategies developed by this population in order to cope with spatio-temporal variations of food availability. This will be approached by identifying daily activity, ranging and grouping patterns, in order to understand how they affect social structure. It should also allow us to define the use of savannahs. Our findings will help determine specific conservations measures for this endangered species. [less ▲]

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See detailHow adaptation strategies of crops could counteract climate change effects? The case of four catchments in Wallonia, Belgium.
Bauwens, Alexandra ULg; Sohier, Catherine ULg; Degré, Aurore ULg

in Geophysical Research Abstracts (2013), 15

A sharp increase in extreme heat and drought stress is projected in Belgium by the end of the 21st century, with the potential to significantly reduce crops’ yields under current agricultural practices ... [more ▼]

A sharp increase in extreme heat and drought stress is projected in Belgium by the end of the 21st century, with the potential to significantly reduce crops’ yields under current agricultural practices. This contribution uses an agro-hydrological model in order to assess the potential effects of climate evolution on crop development, yield, and water balance for the main agricultural productions in the Meuse catchment. Erosion risk is also evaluated. We show that grasslands and maize yield decrease and yield variability increases under climate change scenarios. The leaf area index study permits to put in emphasis the earlier start of the vegetation due to warmer climate. It appears that all the sensitive stages occur earlier in the season and that crops are negatively affected by summer drought stress. The better understanding of crops development under evolving climate allows us to propose some changes in agricultural practices and to assess their effectiveness. We evaluate different strategies of adaptation in agricultural practices in order to reduce the potential negative effects of climate change on grasslands and maize production. Adaptation strategies proposed are advanced sowing and harvesting date, introduction of a cover crop for maize and advance in the cutting dates for grasslands. In the particular case of the Vesdre catchment, shifting the growth period of maize permits to avoid the water-deficit period and allow increased yield. This shift makes it possible to introduce a cover crop that will drastically reduce winter soil erosion. For grassland, the adjustment of the cutting dates favored the first cut and the earlier start of the vegetation. The second cut is less profitable due to summer drought stress. The vulnerability assessments focused on the main rotation encountered in the cultivated areas and in the difference in the cover type of these crops. [less ▲]

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See detailOn differentially dissipative dynamical systems
Forni, Fulvio ULg; Sepulchre, Rodolphe ULg

in IFAC-PapersOnLine website. (2013)

Dissipativity is an essential concept of systems theory. The paper provides an extension of dissipativity, named differential dissipativity, by lifting storage functions and supply rates to the tangent ... [more ▼]

Dissipativity is an essential concept of systems theory. The paper provides an extension of dissipativity, named differential dissipativity, by lifting storage functions and supply rates to the tangent bundle. Differential dissipativity is connected to incremental stability in the same way as dissipativity is connected to stability. It leads to a natural formulation of differential passivity when restricting to quadratic supply rates. The paper also shows that the interconnection of differentially passive systems is differentially passive, and provides preliminary examples of differentially passive electrical systems. [less ▲]

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See detailPatients' preferences for osteoporosis drug therapy : a discrete choice experiment
Hiligsmann, Mickaël ULg; Dellaert, B; Dirksen, C et al

in Osteoporosis International (2013), 24(1), 53

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See detailThe Future of the Past: Architectural Heritage Guides as Handbooks for City Decoding and as a Blueprints for Urban design
Occhiuto, Rita ULg; De Fijter, Arie; Hautecler, Paul-Christian ULg

in Actes du Colloque (2013)

The recent UNESCO Recommendations on the historic hurban landscape insist on the opportunity to "shift from an emphasis on architectural monuments primarly" towards "a landscape approach" including "the ... [more ▼]

The recent UNESCO Recommendations on the historic hurban landscape insist on the opportunity to "shift from an emphasis on architectural monuments primarly" towards "a landscape approach" including "the broader urban context and its geographical setting", to understand historic urban landscape "as the result of a historic layerling, and to create new tools to adress this vision". Along this line of thought of thought, the proposed approach expands the traditional contents of architectural guides, providing keys to reconsider and evaluate the listed works' contribution to the evolution of their immediate surrounding, to the urban structure as a whole, up to the territorial scale. Moving from a design-oriented perspective and using the methods of urban morphology, the work consists mainly of set of original schemes, maps and drawings of Liège and its neighborhoods, as means to reveal the urban structure, its layerling over time, and the role of architectural heritage in clarifuing, enhancing, or even degrading the coherence of the urban artifact. Halfway between popular and scholarly literature, the forthcoming guides aim to become at both times "handbooks for city decoding" and blueprints for urban design. Providing tools lo read, comprehehen, and appreciate the part played by built heritage in a city's evolution and in the shaping of our daily environment helps to understand urban environments as a process bearing the overlapping influences of many experiments, partially implemented plans, competing visions and contradictory ideas. As a result, both the ordinary and specialized audience can possibly raise their awareness and perception of modernist architecture's legacy, but also learn how certain qualities were achieved and how certain local issues came about, acquiring relevant critical keys to take part as stakeholders or designers in the debate over the future city. [less ▲]

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See detailBaseline measurements of COLL2-1 and COLL2-1 NO2 in urine are highly predictive of joint space narrowing in knee osteoarthritis
Henrotin, Yves ULg; Kraus, V.; Huebner, J. et al

in Annals of Rheumatic Diseases (2013)

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See detailMeasurement of cerebrospinal fluid albumin in healthy dogs
Ramery, Eve ULg; Girod, Maud ULg; Allerton, Fergus et al

in Veterinary Clinical Pathology (2013)

Background: Measurement of CSF albumin aids diagnosis in human medicine but technical difficulties related to its low CSF concentration prohibit its routine use in veterinary medicine. High-resolution ... [more ▼]

Background: Measurement of CSF albumin aids diagnosis in human medicine but technical difficulties related to its low CSF concentration prohibit its routine use in veterinary medicine. High-resolution electrophoresis (HRE) has been described but often results in non-interpretable integration profiles preventing albumin determination. Fraction quantification using HRE may be more precise after concentration (cHRE) using a membrane microconcentrator technique but has not been evaluated in CSF with total protein levels below 20mg/dL. Immunoturbidimetry is routinely used for human CSF albumin measurement and was recently applied on canine samples with encouraging results. Objective: The purpose of this study was to compare HRE (including the use of a concentration step) and immunoturbidimetric assay for the measurement of albumin levels in normal canine CSF. Methods: 30 CSF specimens from 15 healthy dogs were evaluated. CSF total protein was measured by the pyrogallol red methoda and CSF albumin was determined by HREb (n=15), cHREc (n=30) and immunoturbidimetric assayd (n=30). Validation of the human immunoturbidimetric assay was performed using a purified canine albumin standarde. Results: Mean CSF total protein was 17.5 (range 7-39) mg/dL. HRE integration profiles were non-interpretable in all unconcentrated specimens. However, clear distinction of the major protein fractions was achieved for all cHRE specimens. CSF albumin levels were measureable in 29/30 specimens using immunoturbidimetry. Excellent correlation (Pearson r=0.92, p<0.001) was found between the two techniques. Conclusion: Immunoturbidimetry and cHRE may be used for routine measurement of CSF albumin. [less ▲]

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See detailTime-Controlled Cryogenic Zone Compression (tCZC) GC-HRMS, A Novel Tool fro Targetted Analysis at Uktra Trace Level
Krumwiede, D; Mehmlann, H; Focant, Jean-François ULg et al

in Organohalogen Compounds (2013), 75

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See detailModeling of Dendritic Cell-based vaccination Immunotherapy using Artificial Neural Networks
Mehrian, Mohammad ULg; Arabameri, Abazar; Sedghi, Alireza et al

in Modeling of Dendritic Cell-based vaccination Immunotherapy using Artificial Neural Networks (2013)

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See detail‘Volkomen Hollands en toch op Europees peil’: E. du Perron over Louis Couperus
Andringa, Kim ULg

in Cahiers voor een lezer (2013), 37

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See detailInhibition of sclerostin with romosozumab in postmenopausal women with low BMD : phase 2 trial results
McClung, M; Grauer, A; Boonen, S et al

in Osteoporosis International (2013), 24(1), 38-39

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See detailPrimary spinal cord ependymoma WHO grade II - a multi-institutional European series of 29 patients
Sperl; Zacharoulis, S; Massimino, M et al

in Pediatric Blood & Cancer (2013)

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See detailValidation of analytical method for the determination in serum of psychotropic drugs commonly prescribed in Rwanda by HPLC-DAD
Hahirwa, Innocent; Charlier, Corinne ULg; DENOOZ, Raphael ULg et al

in Acta Clinica Belgica (2013), 68(6), 479

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See detailThe Enhancement of Secondary Succession by Western Lowland Gorillas (Gorilla gorilla gorilla) in a Moist Tropical Forest of Southeast Cameroon
Petre, Charles-Albert ULg; Haurez, Barbara ULg; Tagg, Nikki et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84

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See detailNutrition and bone health : turning beliefs into knowledge for healthy behaviour
Brandi, ML; Reginster, Jean-Yves ULg

in Osteoporosis International (2013), 24(1), 388-389

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See detailKoaleszenz in Extraktionskolonnen und Abscheidern
Pfennig, Andreas ULg; Buchbender, Florian; Chuttrakul, P et al

in Chemie Ingenieur Technik (2013)

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See detailChirurgie bariatrique chez le patient diabétique de type 1 : résultats d’une expérience limitée.
FRANCK, Marie ULg; DE FLINES, Jenny ULg; PAQUOT, Nicolas ULg et al

in Diabète & Métabolisme (2013), 39(suppl), 102

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See detailStrunian Rugose and Tabulate corals from Northwestern Turkey
Denayer, Julien ULg

in Document de l'Institut Scientifique, Rabat (2013), 26

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See detailOn the Number of Abelian Bordered Words
Rampersad, Narad; Rigo, Michel ULg; Salimov, Pavel ULg

in Lecture Notes in Computer Science (2013), 7907

In the literature, many bijections between (labeled) Motzkin paths and various other combinatorial objects are studied. We consider abelian (un)bordered words and show the connection with irreducible ... [more ▼]

In the literature, many bijections between (labeled) Motzkin paths and various other combinatorial objects are studied. We consider abelian (un)bordered words and show the connection with irreducible symmetric Motzkin paths and paths in Z not returning to the origin. This study can be extended to abelian unbordered words over an arbitrary alphabet and we derive expressions to compute the number of these words. In particular, over a 3-letter alphabet, the connection with paths in the triangular lattice is made. Finally, we study the lengths of the abelian unbordered factors occurring in the Thue--Morse word. [less ▲]

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See detailL’incendie : feu purificateur ?
Close, Florence ULg

in Bulletin de la Société d'Art et d'Histoire du Diocèse de Liège (2013), LXX

Dans la nuit du 3 au 4 août 1312, la Cité de Liège est mise à feu et à sang. Sept siècles plus tard, la mémoire collective liégeoise compte encore cet évènement au nombre des jalons les plus tragiques de ... [more ▼]

Dans la nuit du 3 au 4 août 1312, la Cité de Liège est mise à feu et à sang. Sept siècles plus tard, la mémoire collective liégeoise compte encore cet évènement au nombre des jalons les plus tragiques de l’histoire de la Principauté. Les conditions dans lesquelles moururent les patriciens demeurent inqualifiables, de même que les moyens auxquels recourut la masse populaire révoltée pour venir à bout de son adversaire. Cet évènement anecdotique au regard de la grande histoire met en lumière la place ambivalente du feu dans la vie et la mentalité des hommes et des femmes du Moyen Âge. Il invite à une profonde réflexion mêlant des considérations juridiques, spirituelles, symboliques et anthropologiques [less ▲]

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See detailGenetic analysis of pig survival in a crossbred population
Dufrasne, Marie ULg; Misztal, Ignacy; Tsuruta, Shogo et al

in Journal of Animal Science (2013), 91(E-Suppl.2), 193

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See detailThe interdependent relationship between C dynamics and soil-forming processes in a podzollic chronosequence under a temperate rainforest.
Vermeire, Marie-Liesse; Lavkulich, Les; Cornelis, Jean-Thomas ULg

in Geophysical Research Abstracts (2013), 15

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See detailLaparoscopic liver resection: a single center experience
SZECEL, Delphine ULg; DE ROOVER, Arnaud ULg; DELWAIDE, Jean ULg et al

in Surgical Endoscopy (2013), 27

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See detailGenetic analysis of longitudinal measurements of feed intake in Piétrain sire lines
Dufrasne, Marie ULg; Jaspart, Véronique; Wavreille, José et al

in Journal of Animal Science (2013), 91(E-Suppl.2), 293

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See detailAnalysis of $\alpha_s$ from the realization of quark-hadron duality
Courtoy, Aurore ULg; Liuti, Simonetta

in World Scientific (2013)

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See detailImage-guided failure assessment of human trabecular bone - Inverse finite element modelling for characterization of elastic properties
Zwahlen, Alexander; Christen, David; Ruffoni, Davide ULg et al

in BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK (2013), 58(1),

Local interpretation of micro finite element (mu FE) simulations has become important in different fields of bone biomechanics. Although on an apparent level mu FE has successfully been validated against ... [more ▼]

Local interpretation of micro finite element (mu FE) simulations has become important in different fields of bone biomechanics. Although on an apparent level mu FE has successfully been validated against experiments, local validations are sparse and limited by imaging resolution. At the tissue level heterogeneity of Young's modulus has been reported. Although non-uniform material distribution have been shown to only have a minor influence on the apparent material properties, its impact on local material behaviour is largely unknown. By combining image-guided failure assessment (IGFA) using synchrotron-based-micro-computed tomography, strain mapping and inverse mu FE modelling, we present an experimental and computational framework which will allow studying local effects of intratrabecular heterogeneity of the Young's modulus. [less ▲]

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See detailPrognostic value of FDG PET/CT in patients with lung tumors treated by Cyberknife.
LOVINFOSSE, Pierre ULg; JANVARY, Zsolt Levente ULg; JANSEN, Nicolas ULg et al

in Journal of Nuclear Medicine (The) (2013), 54(SUPPL), 567

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See detailStudy on the sensitivity of three oat varieties to the saddle gall midge, Haplodiplosis marginata (von Roser) (Diptera: Cecidomyiidae)
Censier, Florence ULg; Chavalle, Sandrine ULg; San Martin y Gomez, Gilles et al

in Communications in Agricultural and Applied Biological Sciences (2013), 78(2), 287-292

The saddle gall midge, Haplodiplosis marginata (von Roser, 1840) is a univoltine pest of cereals which occurs in Europe. The larvae feed on stems and attractive saddle-shaped depressions, driving to ... [more ▼]

The saddle gall midge, Haplodiplosis marginata (von Roser, 1840) is a univoltine pest of cereals which occurs in Europe. The larvae feed on stems and attractive saddle-shaped depressions, driving to important yield losses when the galls are numerous. After 40 years without any reporting, large populations of H. marginata and important damage have been observed since 2010 in wheat crops in Belgium, especially in the Flemish Polders where clay soils and intensive farming of cereals favour heavy infestations. According to some research conducted in the 1960s during the last outbreak, oat (Avena sativa L.) is known to be one of the less favourable hosts to the saddle gall midge. Our study was performed in order to assess the host sensitivity of three oat varieties currently grown in Belgium: EVITA, EFFEKTIV and FREDDY. Therefore, oat varieties were sown on infested soil in two separate enclosures in a glasshouse. In the first enclosure, only the three oat varieties were grown; in the second one, these three oat varieties were grown together with two varieties of spring wheat: GRANNY and KWS CHAMSIN. Two parameters were measured: the percentage of leaves with laid eggs, and the number of galls per stem. The percentage of leaves with eggs showed that the infestation was significantly lower on oats when they were in presence of wheat. The egg infestation was also significantly higher on wheat than on oat, which means oat is a much less favourable host plant than spring wheat for egg laying. Oat varieties were significantly different from each other regarding the number of galls per stem, but with very little damage compared to wheat. The FREDDY variety even seemed to be completely resistant to saddle gall midge, as no galls were observed although there was a similar percentage of leaves with eggs for the three oat varieties. Cropping oat could thus contribute to reduce infestations of H. marginata. [less ▲]

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See detailSimultaneous fitting of statistical-model parameters to symmetric and asymmetric fission cross sections
Mancusi, Davide; Charity, R.J; Cugnon, Joseph ULg

in Journal of Physics: Conference Series (2013), 420

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See detailImproving the Accuracy of Monitoring Great Apes in the Wild: A Case Study from Southeast Cameroon
Tagg, Nikki; Willie, Jacob; Petre, Charles-Albert ULg

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84

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See detailResearch Contributions from Lola Ya Bonobo
André, Claudine; Songrady, Judy; Serckx, Adeline ULg et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84

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See detailSpectral Modelling of Massive Binary Systems: The Example of LZ Cep
Palate, Matthieu ULg; Rauw, Grégor ULg; Mahy, Laurent ULg

in Central European astrophysical bulletin (2013)

Despite their importance for many astrophysical processes, massive stars are still not fully understood. Massive binaries offer an attractive way to improve our knowledge of the fundamental properties of ... [more ▼]

Despite their importance for many astrophysical processes, massive stars are still not fully understood. Massive binaries offer an attractive way to improve our knowledge of the fundamental properties of these objects. However, some secondary effects are known to generate variations in the spectra of massive binaries, rendering their analyses more difficult. We present here a new approach to the computation of synthetic spectra of massive binaries at different phases of their orbital cycle. Our model starts with the Roche potential modified by radiation pressure and accounts for the influence of the companion star on the shape and physical properties of the stellar surface. We further account for gravity darkening and reflection effects to compute the surface temperature. Once the local gravity and temperature are determined, we interpolate in a grid of NLTE plan-parallel atmosphere model spectra to obtain the local contribution to the spectrum at each surface points. Then we sum all the contributions, accounting for the Doppler shift, and limb-darkening to obtain the total spectrum. The computation is repeated for different orbital phases and can be compared to the observations to determine the best parameters. We illustrate our method through the example of the LZ Cep system (O9III + ON9.7V). [less ▲]

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See detailGestion de la reproduction dans les troupeaux bovins laitier
Hanzen, Christian ULg; Rao, Anne-Sophie ULg; Theron, Léonard ULg

in Revue Africaine de Santé et de Productions Animales [=RASPA] (2013)

La décision de la commission européenne de mettre fin en 2015 à la politique des quotas laitiers mise en place en 1984 va vraisemblablement bousculer le paysage laitier européen mais aussi mondial. Plus ... [more ▼]

La décision de la commission européenne de mettre fin en 2015 à la politique des quotas laitiers mise en place en 1984 va vraisemblablement bousculer le paysage laitier européen mais aussi mondial. Plus que jamais les grands pays producteurs (Etats-Unis, Canada, France, Allemagne, Pays-Bas, Irlande, Nouvelle-Zélande) vont dans ce contexte de libéralisation et de globalisation de « l’or blanc » se livrer une concurrence effrénée dans laquelle la majorité des producteurs n’auront que peu ou rien à dire. L’augmentation attendue de la production laitière mondiale (15 milliards de litres par an entre 2010 et 2020) résulte bien entendu de l’augmentation de la population mondiale (3,1 milliards entre 1970 et 2010 auxquels s’ajouteront 2 milliards de plus en 2050) mais également du fait que davantage de personnes en Extrême et Moyen-Orient, en Amérique du Sud et en Afrique du Nord consomment davantage de lait et de produits dérivés. L’enjeu pour la majorité des éleveurs européens ou non va être de réduire les coûts liés à la production laitière en (1) optimisant les ressources alimentaires, (2) en améliorant la santé mammaire, (3) en augmentant la longévité des vaches, (4) en réduisant la fréquence des maladies métaboliques, locomotrices ou infectieuses et (5) en améliorant la fécondité. L’amélioration de la fécondité passe définition oblige par la réduction de l’âge du premier vêlage et de l’intervalle entre vêlages. Par gestion, il faut entendre dans un premier temps la quantification du problème et dans un second l’identification des diverses hypothèses diagnostiques qui en sont responsables. Les facteurs de nature alimentaire, thérapeutique, pathologique ou de gestion susceptibles de modifier l'évolution normale de chaque femelle depuis sa naissance jusqu'au moment de sa réforme sont de nature diverse. Ils concernent l'individu ou le troupeau. Ils sont directement ou indirectement responsables de leur fertilité et/ou de leur fécondité. Leurs effets se manifestent de manière isolée ou synergique. Ils concernent aussi bien les animaux que ceux qui en ont la responsabilité sanitaire ou de gestion. Ils sont de nature anatomique, infectieuse, hormonale, thérapeutique ou zootechnique. Par gestion de la reproduction, il faut entendre une approche épidémiologique, globale de l’infécondité qui en intègre les aspects spécifiques sans négliger pour autant les autres aspects qui ne lui sont pas directement liés. Par gestion de la reproduction, on peut aussi comprendre sa gestion hormonale à savoir le recours à des protocoles thérapeutiques de synchronisation des inséminations et donc des vêlages. L’une et l’autre approche s’inscrive dans le contexte d’une identification systématique des animaux à risque au travers d’un suivi mensuel de reproduction. Ce suivi est la clé de voûte d’une gestion de la reproduction. Au travers d’une démarche hypothético-déductive, la présente communication se propose de - quantifier les performances de reproduction au travers des ses principaux paramètres de fécondité et de fertilité : cette première étape est indispensable pour identifier la présence ou non d’un problème d’infécondité, - passer en revue et de manière aussi synthétique que possible les diverses hypothèses et donc les facteurs de risque responsables d’infécondité - proposer des stratégies curatives ou préventives, anti-infectieuses ou hormonales voire zootechniques pour limiter les conséquences de l’infécondité. [less ▲]

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See detailIntraperitoneal Adhesions After Open or Laparoscopic Abdominal Procedure: An Experimental Study in the Rat.
Arung, Willy; Drion, Pierre ULg; Honoré, Pierre ULg et al

in Surgical Endoscopy (2013), 27

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See detailFeasibility and accessibility to the laparoscopic procedures in University Hospital of Kinshasa
Nsadi Fwene, Berthier; Veyi Tadulu, D.; Kazadi Mutshim, JM et al

in Surgical Endoscopy (2013), 27

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See detailValence transversities: the collinear extraction
Courtoy, Aurore ULg; Bacchetta, Alessandro; Radici, Marco

in PoS - Proceedings of Science (2013)

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See detailQuantitative determination of non persistent endocrine disruptors in human urine
Dewalque, Lucas ULg; PIRARD, Catherine ULg; DUBOIS, Nathalie ULg et al

in Acta Clinica Belgica (2013), 68(6),

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See detailOleuropein or rutin consumption decreases the spontaneous development of OA in Hartley guinea pig
Sanchez, Christelle ULg; Horcajada, Marie-Noëlle; Membrez, Fanny et al

in Arthritis and Rheumatism (2013), 65

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See detailProbing the phase of the elastic $pp$ scattering amplitude with vortex proton beams
Ivanov, Igor ULg

in AIP Conference Proceedings (2013)

We show that colliding vortex proton beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the scattering amplitude changes with the scattering angle. In ... [more ▼]

We show that colliding vortex proton beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the scattering amplitude changes with the scattering angle. In elastic $pp$ scattering, this will open a novel way to measure the parameter $\rho(t)$ and probe the real part of the Pomeron. [less ▲]

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See detailBiofilm formation on metal structured packing for the production of high added value biomolecules
Zune, Quentin ULg; Toye, Dominique ULg; Delvigne, Frank ULg et al

in Récents Progrès en Génie des Procédés (2013)

Many white biotechnology bioprocesses apply techniques from chemical engineering based on bioreactors with mechanical stirring system commonly employed in pharmaceutical sector, food industry or energy ... [more ▼]

Many white biotechnology bioprocesses apply techniques from chemical engineering based on bioreactors with mechanical stirring system commonly employed in pharmaceutical sector, food industry or energy field (Dasilva, 2004). As in chemical engineering, scale-up of these bioprocesses induces physicochemical constraints that affect physiological pathways and decrease performances. In this context, it is essential to think new bioprocesses better suited to physiology of microorganisms, minimizing physicochemical constraints. The aim of this work consists to use stainless steel structured packing (SSP) with high specific area (500-750 m²/m³) as inert support for biomass immobilization in order to produce high added value biomolecules. These bioreactors are biocatalysts in which microbial system is immobilized biomass on the form of a biofilm performing bioconversion of a substrate into a specific product (Rosche, 2009). In this study, an experimental setting containing a SSP reproduces solid-state fermentation (SSF) like conditions. Two well known microorganisms for their ability to form biofilm and secrete metabolites are tested in the experimental setting : Bacillus subtilis for its lipopeptides and Aspergillus oryzae for its glucoamylase. Effectiveness of the bioprocess in term of dynamic of the excretion of the target biomolecule is compared with a classical submerged culture (SmF). For lipopeptides production from B. subtilis, SSP is located in a 20L bioreactor continuously aspersed by liquid medium required to the growth of the biofilm. In the case of A. oryzae, the SSP is partially immerged in a 250 mL shake flask. X-ray tomography of the SSP allows non-invasive visualization and quantification of biofilm repartition inside the support. Implementation of SSP permits almost total immobilization of biomass on the form of a mono-species biofilm to the detriment of the liquid phase. Processing of images obtained by X-ray tomography of the SSP provides relevant information for the optimization of the bioprocess. For both microorganism species, results indicate the influence of parameters such as hydrodynamics, aeration rate and microorganism specificity, on the biofilm morphology inside the support and the performances of the bioprocess. SSF-like conditions in the experimental setting lead to technologic progress, such as absence of foam formation, persistence of the microbial system, and improve the dynamic of metabolites excretion compared with conditions imposed by the submerged culture. Further experiment will consider hydrodynamics aspects and amount of carbon source on effectiveness of the bioprocess. [less ▲]

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See detailSpatial distribution of erosion and deposition on an agricultural watershed
Pineux, Nathalie ULg; Colinet, Gilles ULg; Degré, Aurore ULg

in Geophysical Research Abstracts (2013), 15

To better understand the agricultural landscapes evolution becomes an essential preoccupation and, for this, it is needed to take into account the sediments deposition, in a distributed way. As it is not ... [more ▼]

To better understand the agricultural landscapes evolution becomes an essential preoccupation and, for this, it is needed to take into account the sediments deposition, in a distributed way. As it is not possible in practice to study all terrestrial surfaces in detail by instrumenting sectors to obtain data, models of prediction are valuable tools to control the current problems, to predict the future tendencies and to provide a scientific base to the political decisions. In our case, a landscape evolution model is needed, which aims at representing both erosion and sedimentation and dynamically adjusts the landscape to erosion and deposition by modifying the initial digital elevation model. The Landsoil model (Landscape design for Soil conservation under soil use and climate change), among others, could fulfil this objective. It has the advantage to take the soil variability into account. This model, designed for the analysis of agricultural landscape, is suitable for simulations from parcel to catchment scale, is spatially distributed and event-based. Observed quantitative data are essential (notably to calibrate the model) but still limited. Particularly, we lack observations spatially distributed on the watershed. For this purpose, we choose a watershed in Belgium (Wallonia) which is a 124 ha agricultural zone in the loamy region. Its slopes range from 0% to 9%. To test the predictions of the model, comparisons will be done with: - sediment measurements which are done with water samplings in four points on the site to compare the net erosion results; - sediment selective measurements (depth variation observed along graduated bares placed on site) to compare the erosion and deposition results; - very accurate DSM’s (6,76 cm pixel resolution X-Y) obtained by the drone (Gatewing X100) each winter. Besides planning what the landscape evolution should be, a revision of the soil map (drew in 1958) is organized to compare with the past situation and establish how the landscape moved in 50 years. The first results of the sediment measurements and of the pictures of the drone will be showed in the presentation. [less ▲]

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See detailImportance of LUC and ILUC on the carbon footprint of bioproduct:case of bio-HDPE
Belboom, Sandra ULg; Léonard, Angélique ULg

in International seminar on society and materials (2013)

Due to the depletion of fossil fuels and the increase of greenhouse gas emissions, solutions are needed to replace petrol based products. As a consequence, the number of biobased products developed using ... [more ▼]

Due to the depletion of fossil fuels and the increase of greenhouse gas emissions, solutions are needed to replace petrol based products. As a consequence, the number of biobased products developed using agricultural feedstock is continuously increasing. This study focuses on the carbon footprint of bio-HDPE produced either from Brazilian sugar cane or Belgian sugar beet. The goal of this study is to compare the carbon footprint of bio-HDPE with the fossil one, taking into account the effect of land use change. Common boundaries of the agricultural systems comprise the cultivation step for both crops, i.e. sugar cane and sugar beet, with all associated energy and fertilizer consumptions, the transportation step from field to the industrial plant, the sugar crops transformation into hydrate bioethanol, the by-products valorisation, the dehydration and polymerization steps and the HDPE incineration as end of life issue. Fossil scenario includes the production of ethylene, its polymerization and its incineration. When comparing the entire life cycle of bio and fossil HDPE, the GHG emissions are lower for the biobased product which is the willing effect. This result is only valid if no Land Use Change (LUC) or Indirect Land Use Change (ILUC) effect appears. To assess the environmental impact of the deforestation or of the transformation of a pasture into a field, the EC-Guidelines from the European Union were used in order to calculate the CO2 emissions depending on several parameters. For sugar cane, LUC consists in the transformation of pastures into fields in the region of Sao Paulo in Brazil. Three scenarios can be developed based on different agricultural practices for pasture and field (tillage and fertilizers inputs): the best, the worst and the average. The best case leads to a supplementary environmental gain. The worst and average achieve additional emissions. A payback time, considering the time needed to find again an environmental gain compared to the fossil counterpart, was calculated for the average scenario which is equal to 12 years. The ILUC effect for sugar cane is assumed to be deforestation due to the transformation of forest into pasture induced by the previous LUC effect. The rate of deforestation can vary between 16% or 100% depending on used statistics and leads to a payback time of respectively 26 and 101 years. For sugar beet, no LUC is considered. Indeed, no land expansion is available in Belgium due to small available areas. In the case of an increase of bioplastics production, Belgium should import sugar beet from neighboring countries which can induce ILUC. In this study, sugar beet is assumed to be provided by the Netherlands on pastures previously transformed into fields. The average scenario implies a payback time of 8 years. This study permits to highlight the importance of LUC and ILUC especially for energetic crops dedicated to replace fossil products. This effect can reverse expected results and induce long payback times. [less ▲]

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See detailBlood lead, urinary lead, urinary δ-aminolevulinic acid and urinary porphyrins levels among people living in kinshasa, D.R. Congo : a pilot biomonitoring study
Mputu Malolo, Corneille-Liévin; Ndelo di Phanzu, Josaphat; Marini Djang'Eing'A, Roland ULg et al

in Acta Clinica Belgica (2013), 68(6), 475

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See detailPrevalence of vitamin D inadequacy in European postmenopausal women aged over 80 years
Bruyère, Olivier ULg; Slomian, Justine ULg; Beaudart, Charlotte ULg et al

in European Geriatric Medicine (2013), 4(S1), 13-14

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See detailPhysico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration
Nasir, Mehmet Nail ULg; Legrand, Vincent; Gatard, Sylvain et al

in MATEC Web of Conferences (2013), 4

Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the ... [more ▼]

Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the pharmaceutical and cosmetic fields. Until now, no detailed analyses of the physico-chemical properties of these compounds have been undertaken. Two symmetrical D-xylose-based bolaforms were chemically synthesized where the two xylose heads are linked via an acetal link to a hydrocarbon chain containing 18 carbon atoms and an unsaturation. The two bolaforms differ only by their anomeric configuration: or The bolaform exhibits interfacial properties at the air-water interface which is not the case for the . FTIR spectroscopy showed that the interactions between the bolaform and POPC, a model phospholipid, involve the carbonyl groups of the phospholipid [less ▲]

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See detailExperimental and numerical study of TA6V mechanical behavior under different quasi-static strain paths at room temperature
Gilles, Gaëtan ULg; Habraken, Anne ULg; Cazacu, Oana et al

in AIP Conference Proceedings (2013), 1532

This paper presents an experimental study of the quasi-static mechanical behavior of TA6V titanium alloy. Different monotonic tests were carried out in several orientations in the plane of the sheet in ... [more ▼]

This paper presents an experimental study of the quasi-static mechanical behavior of TA6V titanium alloy. Different monotonic tests were carried out in several orientations in the plane of the sheet in order to characterize the anisotropy and the tension-compression asymmetry exhibited by the material. Initial yielding is modeled by the phenomenological CPB06 criterion and Voce's isotropic hardening is used to describe its evolution. The simulation of a deep-drawing process is performed using the proposed constitutive modeling and compared with experimental data. [less ▲]

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See detailPrediction of residual stresses by FE simulations on bimetallic work rolls during cooling
Neira Torres, Ingrid ULg; Gilles, Gaëtan ULg; Tchuindjang, Jérôme Tchoufack ULg et al

in Computer Methods in Materials Science (2013), 13(1), 84-91

Bimetallic rolls used in the roughing stands of the Hot Strip Mill require mixed properties as a high wear resistance for the shell material and an enhanced toughness for the core material. The bimetallic ... [more ▼]

Bimetallic rolls used in the roughing stands of the Hot Strip Mill require mixed properties as a high wear resistance for the shell material and an enhanced toughness for the core material. The bimetallic roll studied in this paper is obtained from a vertical spin casting process followed by cooling and subsequent heat treatments. Failure of the compound roll sometimes occurs during the cooling stage of the casting route or later during the thermal treatments. It requires to deeply investigate the thermo mechanical metallurgical interactions generated during cooling and heat treatment in order to find the origin of cracks. For this purpose, a thermo metallurgic mechanical finite element model is used. However these numerical simulations require a high amount of mechanical, thermal and metallurgical parameters. In order to determinate these parameters, a study of available data for estimation of mechanical parameters was performed. Thermo physical parameters were obtained by DTA and DSC methods. Metallurgical characterization by inverse numerical method based on available CCT diagrams was performed to determine the TTT diagrams. First cooling numerical simulations are presented, allowing a rough estimate of residual stresses values and the identification of key parameters for predicting accurate residual stresses by sensitivity analysis. [less ▲]

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See detailProcessing of Ti alloys by additive manufacturing: a comparison of the microstructures obtained by laser cladding, selective laser melting and electron beam melting
Reginster, Sylvie ULg; Mertens, Anne ULg; Paydas, Hakan ULg et al

in Materials Science Forum (2013), 765

Additive manufacturing processes such as laser cladding (LC) or selective laser melting (SLM) appear very promising in view of an economic near-net-shape production – and also, in the case of LC, the ... [more ▼]

Additive manufacturing processes such as laser cladding (LC) or selective laser melting (SLM) appear very promising in view of an economic near-net-shape production – and also, in the case of LC, the restoration - of complex and (almost) fully dense parts from Ti alloys. Both techniques involve the melting of a metallic powder with a laser. In the SLM process, the metallic powder is deposited layer by layer in a powder bed and then molten locally according to the desired shape, whereas in LC, the metallic powder is directly projected onto a substrate through a nozzle coaxial with the laser beam. The present research aims at comparing Ti-6Al-4V samples processed by these two techniques with reference samples produced by electron beam melting (EBM), another well established additive manufacturing process (patented by Arcam AB Company) in which a powder bed is molten locally by means of an electron beam. In all three processes, the melt pool undergoes an ultrafast cooling and solidifies very rapidly once the beam has left the area, thus giving rise to strongly out-of-equilibrium microstructures. Yet, each one of these processes also has its own specificities e.g. in terms of scanning strategy and of working atmosphere (low vacuum vs. protective Ar flow). In the present work, the microstructures obtained by these three processes have been compared in details, with a particular attention for characteristics such as porosity, grain size, and the various phases present. Since epitaxial growth of the newly deposited layer on the material previously solidified has been shown [1, 2] to exert a strong influence on the microstructure and on the resulting mechanical properties, great care has been taken to study the microstructural anisotropy associated with each one of the three processes. [less ▲]

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See detailSterile neutrinos and $R_K$
Vicente, Avelino ULg

in Journal of Physics: Conference Series (2013), 447

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See detailSymmetries in multi-Higgs-doublet models
Ivanov, Igor ULg; Vdovin, Evgeny

in AIP Conference Proceedings (2013)

We report the recent progress in understanding of symmetries which can be implemented in the scalar sector of electroweak symmetry breaking models with several Higgs doublets. In particular we present the ... [more ▼]

We report the recent progress in understanding of symmetries which can be implemented in the scalar sector of electroweak symmetry breaking models with several Higgs doublets. In particular we present the list of finite reparametrization symmetry groups which can appear in the three-Higgs-doublet models. [less ▲]

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See detailQuadripulse Repetitive Transcranial Magnetic Stimulation on Visual Cortex for Chronic Migraine Prevention: A Pilot-Trial
Sasso d'Elia, Tullia; Vigano, Alessandro; Fataki, Michel et al

in Cephalalgia : An International Journal of Headache (2013), 33(8), 49

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See detailCorrelation between RNA and protein levels in a large european series from the LYSA
Bossard, C.; Dobay, M.P.; Lamant, L. et al

in Hematological Oncology (2013), 31 Suppl.1

Introduction: CD22 is expressed on most B-non-Hodgkin lymphomas (NHL); inotuzumab ozogamicin (INO) is an anti-CD22 antibody conjugated to calicheamicin. This study evaluated the safety and tolerability of ... [more ▼]

Introduction: CD22 is expressed on most B-non-Hodgkin lymphomas (NHL); inotuzumab ozogamicin (INO) is an anti-CD22 antibody conjugated to calicheamicin. This study evaluated the safety and tolerability of INO plus R-CVP in patients (pts) with relapsed/refractory CD22+ B-NHL. Efficacy data were also collected. Methods: Part 1 of this open-label study identified a maximum tolerated dose (MTD) of INO 0.8mg/m,2 on day 2 plus R-CVP (rituximab 375mg/m,2 cyclophosphamide 750mg/m,2 and vincristine 1.4mg/m,2 on day 1; prednisone 40mg/m,2 on days 1-5) every 21 days. Subsequently, pts were enrolled in the MTD confirmation cohort (part 2, n = 10), which required a dose-limiting toxicity rate of <33% in cycle 1 and <4 pts discontinuing prior to cycle 3 due to an adverse event (AE) in the MTD expansion cohort (part 3, n = 22), which explored preliminary activity. Results: Parts 2 and 3 enrolled 32 pts: 16 pts with diffuse large B-cell lymphoma, 15 with follicular lymphoma and one with mantle cell lymphoma. Median age was 64.5 years (range 44-81 years); 34% of pts had 1 prior regimen, 34% had 2, 28% had ≥3 and 3% had none (median 2; range 0-6).Median treatment duration was five cycles (range 1-6). Part 2 confirmed the MTD as standard dose R-CVP plus INO 0.8mg/m,2; 2/10 pts had a dose-limiting toxicity (grade 3 increased ALT/AST, grade 4 neutropenia requiring G-CSF). One pt discontinued because of an AE prior to cycle 3. Common treatment-related AEs were thrombocytopenia (78%), neutropenia (66%), fatigue (50%), leukopenia (50%), nausea (41%) and lymphopenia (38%); common grade 3/4 AEs were neutropenia (63%), thrombocytopenia (53%), leukopenia (38%) and lymphopenia (31%). There was one case of treatment-related fatal pneumonia with grade 4 neutropenia. Ten pts discontinued treatment due to AEs; thrombocytopenia/delayed platelet recovery was the leading cause (grade 1/2, n = 6; grade 3/4, n = 3). Objective response rate (ORR) was 77% (n = 24/31 evaluable pts), including 26% (n=8/31) with complete response (CR); three pts had stable disease. Of the pts with follicular lymphoma, ORR was 100% (n = 15/15), including seven pts with CR. Of the pts with diffuse large B-cell lymphoma, ORR was 60% (n = 9/16), including one pt with CR. Conclusions: Results suggest that INOplus R-CVP has acceptable toxicity and promising activity in relapsed/refractory CD22+ B-NHL. The most common grade 3/4 AEs were hematologic. Follow-up for progression-free and overall survival is ongoing. [less ▲]

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See detailFirst steps towards an explicit modeling of aba production and translocation in relation with the water uptake dynamics
Lobet, Guillaume ULg; Pagès, Loic; Draye, Xavier

in Acta Horticulturae (2013), 991

Water flow in the plant continuum is thought to be controlled by the leaf, xylem and the root radial conductances. Leaf conductance is widely recognized as the master control in the system as it can act ... [more ▼]

Water flow in the plant continuum is thought to be controlled by the leaf, xylem and the root radial conductances. Leaf conductance is widely recognized as the master control in the system as it can act as a switch in the water flow, even under high transpiration demand. The control of the stomatal aperture by the plant has been the object of numerous research projects since decades and different models have been developed to study stomatal regulation. The plant hormone abscisic acid (ABA) produced in the leaves acts as an endogenous signal triggering stomatal closure, but is also thought to act as a long distance signal that is produced by roots experiencing water deficit. However, the relative contributions of leaf-supplied ABA, root-supplied ABA and xylem water potential in the regulation of water flow remains a matter of controversy. Using a novel functional structural plant model (PlaNet-Maize-ABA), we report here a first attempt to explicitly simulate ABA production, degradation, translocation in all plant organs and their effect on the transpiration flow. [less ▲]

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See detailComparison of Immune Reconstitution after Hematopoietic Stem Cell Transplantation with Flu-TBI versus TLI-ATG Conditioning
Hannon, Muriel ULg; Humblet-Baron, S.; Graux, C. et al

in Belgian Journal of Hematology (2013), Abstracts book(Supplement of 28th General Meeting of the Belgian Hematological Society), 38

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See detailIndirect comparison of bazedoxifene vs. oral bisphosphonates for the prevention of vertebral fractures in postmenopausal osteoporotic women
Reginster, Jean-Yves ULg; Ellis, AG; Luo, X et al

in Osteoporosis International (2013), 24(1), 37

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See detailLa consommation d’oleuropéine ou de rutine diminue le développement spontané de l’arthrose chez le cobaye Hartley
Sanchez, Christelle ULg; Horcajada, Marie-Noëlle; Membrez, Fanny et al

in Revue du Rhumatisme (2013), 80S

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See detailDeciphering the role of 75KDA SIRT1 fragment in osteoarthritis
Dvir-Ginzberg, M; Oppenheimer, H; Meir, H et al

in Osteoarthritis and Cartilage (2013), 21

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See detailImpairments of 3D visual perception in posterior cortical atrophy: functional and anatomical characterization
Gillebert, Céline; Bastin, Christine ULg; Sunaert, Stefan et al

in Alzheimer's & Dementia : The Journal of the Alzheimer's Association (2013), 9(4), 524

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See detailModeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo
Crowet, Jean-Marc ULg; Lins, Laurence ULg; Deshayes, Sébastien et al

in European Biophysics Journal [=EBJ] (2013), 42(S1), 63

CADY is a cell-penetrating peptide spontaneously making non-covalent complexes with short interfering RNAs (siRNAs) in water. Neither the structure of CADY nor that of the complexes is resolved. We have ... [more ▼]

CADY is a cell-penetrating peptide spontaneously making non-covalent complexes with short interfering RNAs (siRNAs) in water. Neither the structure of CADY nor that of the complexes is resolved. We have calculated and analyzed 3D models of CADY and of the non-covalent CADY–siRNA complexes in order to understand their formation and stabilization. Data from the ab initio calculations and molecular dynamics support that, in agreement with the experimental data, CADY is a polymorphic peptide partly helical. We calculated and compared several complexes with peptide/siRNA ratios of up to 40. The initial binding of CADYs is essentially due to the electrostatic interactions of the arginines with siRNA phosphates. Due to a repetitive arginine motif (XLWR(K)), CADYs can adopt multiple positions at the siRNA surface. Nevertheless, several complex properties are common: an average of 14 ± 1 CADYs is required to saturate a siRNA. The 40 CADYs/siRNA that is the optimal ratio for vector stability always corresponds to two layers of CADYs per siRNA and the peptide cage is stabilized by hydrophobic CADY–CADY contacts. The analysis demonstrates that the hydrophobicity, the positive charges and the polymorphism of CADY are mandatory to make stable the CADY–siRNA complexes. [less ▲]

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See detailModélisation du captage post-combustion du CO2 avec évaluation de la dégradation des solvants
Léonard, Grégoire ULg; BELLETANTE, Ségolène; Cabeza Mogador, Bruno et al

in Récents Progrès en Génie des Procédés (2013), 104

Post-combustion CO2 capture in power plants is one of the most mature technologies for a short-term and large-scale decrease of CO2 emissions while simultaneously addressing the growing global energy ... [more ▼]

Post-combustion CO2 capture in power plants is one of the most mature technologies for a short-term and large-scale decrease of CO2 emissions while simultaneously addressing the growing global energy demand. CO2 is chemically absorbed in an amine solvent that can be regenerated at higher temperature, producing a pure CO2 stream. However, the large impact of this technology on the power plant efficiency and the environmental penalty are the main drawbacks for large-scale implementation. In this work, an innovative approach combining process modeling and evaluation of the environmental penalty due to amine degradation is presented. Based on experimental results, the kinetics of solvent oxidative and thermal degradation is estimated and included in the process model developed in Aspen Plus. Using this model, the influence of operating parameters like the oxygen concentration in the flue gas or the solvent regeneration pressure is studied. This model is a first step for a multi-objective optimization of the CO2 capture process, assessing both energy and environmental penalties of this technology. [less ▲]

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See detailApplication de la résonance magnétique nucléaire (RMN) en toxicologie judiciaire
Denooz, Raphaël ULg; Frederich, Michel ULg; Charlier, Corinne ULg et al

in Acta Clinica Belgica (2013), 68(6), 470

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See detailHerbaceous Plant Availability and Use by Western Lowland Gorillas in South East Cameroon
Willie, Jacob; Tagg, Nikki; Petre, Charles-Albert ULg et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84

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See detailSystemic Active and Total Myeloperoxidase Levels in Coronary Artery Disease.
GACH, Olivier ULg; MAGNE, Julien ULg; Franck, Thierry ULg et al

in Cardiology (2013), 126(Suppl. 2), 1-521

Backgound: Measurement of total Myeloperoxidase (MPO) by ELISA is considered as a marker of neutrophil activation but is not the true indicator of the degree of its activity. In a dynamic pathology such ... [more ▼]

Backgound: Measurement of total Myeloperoxidase (MPO) by ELISA is considered as a marker of neutrophil activation but is not the true indicator of the degree of its activity. In a dynamic pathology such as atherosclerosis, it may be important to measure the real active part of MPO because it represents the true witness of the oxidant potential of the enzyme. Aim: To identify the relation between coronary artery disease identified by coronaro-angiography on measured serum total and active MPO levels and evaluate the correlation between these MPO levels and the presence of clinically defined unstable condition. Methods: Prospective analyse of serum samples of patients before (within 30 min) coronaro-angiography. Total and active MPO concentrations were assessed by sandwich Elisa and SIEFED® method’s respectively. Results: Two hundred and twenty patients were included in this study (age: 66.1±10.7 years, 67% of male). Among these, 62% presented significant coronary artery disease (stenosis more than 60% at least in one épicardial coronary artery). Twenty four patients (11%) presented unstable coronary syndrome. Mean active and total MPO in the general population were 50.1±63.5 and 147.6±223.3 ng.mL-1 respectively. In comparison, mean active MPO was 47.1±47.9 ng.mL-1 in stable patients and 75.1±135.2 ng.mL-1 in unstable patients (p=0.04). Mean total MPO was 146.3±224.7 ng.mL-1 in stable patients and 158.2±215.8 ng.mL-1 in the unstable’s one (p=0.8). There was a significant correlation between active MPO levels and instability (r=0.14, p=0.04) not present for total MPO levels (r=0.016, p=0.8). Conclusion: We observed a correlation between active MPO and clinical instability while there was no correlation with total MPO. Our preliminary results suggest that this marker could be a powerful indicator of instability which could possess an important prognostic impact. This hypothesis requires an evaluation in wider population and during a prolonged follow-up. [less ▲]

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See detailLocal estradiol synthesis in the brain and its implication in male and female sexual motivation of Japanese quail
de Bournonville, Catherine ULg; Schmit, Mélanie; Ball, Gregory F et al

in Trabajos del Instituto Cajal (2013)

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See detailFirst retrievals of HCFC-142b from ground-based high resolution FTIR solar observations: application to high altitude Jungfraujoch spectra
Mahieu, Emmanuel ULg; O'Doherty, Simon; Reimann, Stefan et al

in Geophysical Research Abstracts (2013), 15

Hydrofluorocarbons (HCFCs) are the first substitutes to the long-lived ozone depleting halocarbons, in particular the chlorofluorocarbons (CFCs). Given the complete ban of the CFCs by the Montreal ... [more ▼]

Hydrofluorocarbons (HCFCs) are the first substitutes to the long-lived ozone depleting halocarbons, in particular the chlorofluorocarbons (CFCs). Given the complete ban of the CFCs by the Montreal Protocol, its Amendments and Adjustments, HCFCs are on the rise, with current rates of increase substantially larger than at the beginning of the 21st century. HCFC-142b (CH3CClF2) is presently the second most abundant HCFC, after HCFC-22 (CHClF2). It is used in a wide range of applications, including as a blowing foam agent, in refrigeration and air-conditioning. Its concentration will soon reach 25 ppt in the northern hemisphere, with mixing ratios increasing at about 1.1 ppt/yr [Montzka et al., 2011]. The HCFC-142b lifetime is estimated at 18 years. With a global warming potential of 2310 on a 100-yr horizon, this species is also a potent greenhouse gas [Forster et al., 2007]. First space-based retrievals of HCFC-142b have been reported by Dufour et al. [2005]. 17 occultations recorded in 2004 by the Canadian ACE-FTS instrument (Atmospheric Chemistry Experiment – Fourier Transform Spectrometer, onboard SCISAT-1) were analyzed, using two microwindows (1132.5–1135.5 and 1191.5–1195.5 cm-1). In 2009, Rinsland et al. determined the HCFC-142b trend near the tropopause, from the analysis of ACE-FTS observations recorded over the 2004–2008 time period. The spectral region used in this study extended from 903 to 905.5 cm-1. In this contribution, we will present the first HCFC-142b measurements from ground-based high-resolution Fourier Transform Infrared (FTIR) solar spectra. We use observations recorded at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl), with a Bruker 120HR instrument, in the framework of the Network for the Detection of Atmospheric Composition Change (NDACC, visit http://www.ndacc.org). The retrieval of HCFC-142b is very challenging, with simulations indicating only weak absorptions, lower than 1% for low sun spectra and current concentrations. Among the four microwindows tested, the region extending from 900 to 906 cm-1 proved to be the most appropriate, with limited interferences, in particular from water vapor. A total column time series spanning the 2004-2012 time period will be presented, analyzed and critically discussed. After conversion of our total columns to concentrations, we will compare our results with in situ measurements performed in the northern hemisphere by the AGAGE network. [less ▲]

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See detailPhenomenology of $\alpha_s$ at intermediate energy: the quark-hadron duality approach
Courtoy, Aurore ULg

in PoS - Proceedings of Science (2013)

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See detailLe ranélate de strontium diminue la proportion de patients progressant rapidement dès la première année : une analyse post hoc de l'étude SEKOIA
Chevalier, X; Richette, P; Bruyère, Olivier ULg et al

in Revue du Rhumatisme (2013), 80(S1), 59-60

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See detailIn silico simulations of bone remodeling with improved parameter estimation from local strains and dynamic morphometry in vivo
Levchuk, Alina; Sommer, Remo; Badilatti, Sandro D. et al

in JOURNAL OF BONE AND MINERAL RESEARCH (2013), 28(1),

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See detailSiblings and coming-out
Haxhe, Stéphanie ULg; D'Amore, Salvatore ULg

in Psychology, Community & Health (2013), 2(2), 162

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See detailPartonic Picture of Generalized Transverse Momentum Distributions
Liuti, Simonetta; Courtoy, Aurore ULg; Goldstein, Gary R. et al

in World Scientific (2013)

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See detailLa Meuse comme "Barrière" ? Regards croisés sur une frontière stratégique entre la France et l'Allemagne (1870-1914)
Bechet, Christophe ULg

in Revue Belge de Philologie et d'Histoire (2013), XCI(4), 1155-1186

In the margins of the London Treaty of 1831, a secret provision – regarding the defence of the Belgian fortresses in case of a war against France by the other Powers was maintained, putting the strategic ... [more ▼]

In the margins of the London Treaty of 1831, a secret provision – regarding the defence of the Belgian fortresses in case of a war against France by the other Powers was maintained, putting the strategic burden of the old « Low Countries Barrier » of 1815 on the frail shoulders of the newly-formed Kingdom of Belgium. To the full satisfaction of the Belgian Government, this « Fortress agreement » was practically forgotten afterwards. Nevertheless, after the Franco-Prussian War of 1870-1871, a march of the French and German armies through the Meuse valley became more and more a nightmarish eventuality. As a consequence, the towns of Liège and Namur were surrounded with modern forts to check any invasion attempt by belligerents. This shift in defensive paradigm led to numerous diplomatic and military commentaries in Belgium and abroad. Meanwhile, the new railways established between Meuse and Rhin increased the strategic value of the Ardennes-Eifel area. Finally, these modifications to the border area distorted the French and German war plans. At the beginning of the twentieth century, war-planners had started to look at the Belgian Meuse valley from a completely new perspective. [less ▲]

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See detailDevelopment of a non lethal sampling method to monitor immune response and disease progression in salmonid fish
Mira Monte, Milena ULg; Urquhart, K.; Hoare, R. et al

in Fish and Shellfish Immunology (2013)

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See detailVisean corals from the transverse Jebel Begaa to Gara el Itima (eastern Tafilalt, Morocco)
Aretz, Markus; Denayer, Julien ULg

in Document de l'Institut Scientifique, Rabat (2013), 26

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See detailStudy of a solar concentrator for space based on a diffractive/refractive optical combination
Michel, Céline ULg; Loicq, Jerôme ULg; Languy, Fabian ULg et al

in AIP Conference Proceedings (2013), (1556), 97-100

This paper presents a new design of a planar solar concentrator for space applications focusing on two spatially separated PV cells, allowing independent control of output power of each cell. It has the ... [more ▼]

This paper presents a new design of a planar solar concentrator for space applications focusing on two spatially separated PV cells, allowing independent control of output power of each cell. It has the advantages of both spectral splitting and solar concentration by the combination of a blaze transmission diffraction grating and a flat cylindrical Fresnel lens. An optical optimization has been realized and two variations of configuration have been developed to improve tracking tolerance: first, a design completed by secondary reflective concentrators and second, a symmetrical configuration composed of two lenses. First numerical results are presented, highlighting the possibility to design a concentrator at about 10×, with an electrical output power about 290W/m² lens and less than 10% losses for tracking errors lower than ±0.9°. [less ▲]

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