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See detailPreliminary evaluation of the di raction behind the PROBA 3/ASPIICS optimized occulter
Baccani, Cristian; Thizy, Cédric ULg; Renotte, Etienne ULg

in Proceedings of SPIE (2016, June)

PROBA-3 is a technological mission of the European Space Agency (ESA), devoted to the in-orbit demon- stration of formation ying (FF) techniques and technologies. ASPIICS is an externally occulted ... [more ▼]

PROBA-3 is a technological mission of the European Space Agency (ESA), devoted to the in-orbit demon- stration of formation ying (FF) techniques and technologies. ASPIICS is an externally occulted coronagraph approved by ESA as payload in the framework of the PROBA-3 mission and is currently in its C/D phase. FF o ers a solution to investigate the solar corona close the solar limb using a two-component space system: the external occulter on one spacecraft and the optical instrument on the other, separated by a large dis- tance and kept in strict alignment. ASPIICS is characterized by an inter-satellite distance of 144 m and an external occulter diameter of 1.42 m. The stray light due to the di raction by the external occulter edge is always the most critical o ender to a coronagraph performance: the designer work is focused on reducing the stray light and carefully evaluating the residuals. In order to match this goal, external occulters are usually characterized by an optimized shape along the optical axis. Part of the stray light evaluation process is based on the di raction calculation with the optimized occulter and with the whole solar disk as a source. We used the eld tracing software VirtualLabTM Fusion by Wyrowski Photonics [1] to simulate the di raction. As a rst approach and in order to evaluate the software, we simulated linear occulters, through as portions of the ight occulter, in order to make a direct comparison with the Phase-A measurements [2]. [less ▲]

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See detailVUV Optical Ground System Equipment and its application to the ICON FUV flight grating characterization and selection
Blain, Pascal ULg; Desselle, Richard ULg; Domken, Isabelle ULg et al

in Advances in Optical and Mechanical Technologies for Telescopes and Instrumentation (2016, June)

ICON FUV is a two channel spectrographic imager that measures intensity and spatial distribution of oxygen (135.6 nm) and molecular nitrogen (157 nm) of the ionosphere. As those wavelengths are strongly ... [more ▼]

ICON FUV is a two channel spectrographic imager that measures intensity and spatial distribution of oxygen (135.6 nm) and molecular nitrogen (157 nm) of the ionosphere. As those wavelengths are strongly absorbed by the atmosphere, the optical elements of the system have to be tested inside vacuum chambers. Prior to the instrument alignment and calibration, two 3600 gr/mm gratings were characterized. The primary focus is the measurement of the diffraction efficiencies; while the second objective is to select the best grating and to define which is the flight and the spare. A dedicated setup has been developed to assess the grating optical performances under vacuum. A 1 cm diameter collimated beam is generated using an off-axis parabola and a UV source at its focal point. The grating is placed at the center of two rotation stages collinearly aligned. One detector is placed on a rotating arm, deported from its rotation center. A PMT detector records diffracted light intensity with respect to its angular position and its wavelength. Angular incidence on the grating is tuned with the help of the second rotation stage. The grating efficiency homogeneity and scattering properties are measured through a Y-X scan. [less ▲]

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See detailOptical design and optical properties of a VUV spectrographic imager for ICON mission
Loicq, Jerôme ULg; Kintziger, Christian ULg; Mazzoli, Alexandra ULg et al

in Proceedings of SPIE (2016, June)

In the frame of the ICON (Ionospheric Connection Explorer) mission of NASA led by UC Berkeley, CSL and SSL Berkeley have designed in cooperation a new Far UV spectro-imager. The instrument is based on a ... [more ▼]

In the frame of the ICON (Ionospheric Connection Explorer) mission of NASA led by UC Berkeley, CSL and SSL Berkeley have designed in cooperation a new Far UV spectro-imager. The instrument is based on a Czerny-Turner spectrograph coupled with two back imagers. The whole field of view covers [± 12° vertical, ± 9° horizontal]. The instrument is surmounted by a rotating mirror to adjust the horizontal field of view pointing by ± 30°. To meet the scientific imaging and spectral requirements the instrument has been optimized. The optimization philosophy and related analysis are presented in the present paper. PSF, distortion map and spectral properties are described. A tolerance study and alignment cases were performed to prove the instrument can be built and aligned. Finally straylight and out of band properties are discussed. [less ▲]

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See detail188Re and 68Ga radiolabeled Starch-Based Microparticles as potential theranostic radiopharmaceutical for Hepatocellular Carcinoma
Verger, Elise ULg; Drion, Pierre ULg; MEFFRE, Geneviève ULg et al

in Journal of Nuclear Medicine (The) (2016, May 01), 57(suppl. 2),

The SBMP as a unique vector is a promising theranostic agent for the SIRT of HCC.

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See detailRoof Frames in the Buit Heritage of Brussels (Belgium): The contribution of dendrochronology and written sources
Weitz, Armelle ULg; Charruadas, Paulo; Fraiture, Pascale et al

in Tree Rings in Archaeology, Climatology and Ecology (2016, May), 14

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See detailMicroparticules à base d’amidon radiomarquées au 188Re et 68Ga comme agent théranostique pour la radiothérapie interne sélective du carcinome hépatocellulaire
Verger, Elise ULg; Drion, Pierre ULg; MEFFRE, Geneviève ULg et al

in Médecine Nucléaire (2016, May), 40(3), 182

Les microparticules SBMP, en étant capable d'être radiomarquées rapidement, de manière reproductible, sous forme de kits prêt-à-l‘emploi, par du 188Re et du 68Ga, se révèlent être un outil théranostique ... [more ▼]

Les microparticules SBMP, en étant capable d'être radiomarquées rapidement, de manière reproductible, sous forme de kits prêt-à-l‘emploi, par du 188Re et du 68Ga, se révèlent être un outil théranostique prometteur pour le traitement du carcinome hépatocellulaire. [less ▲]

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See detailModelling Urban Expansion: A Multiple Urban-Densities Approach
El Saeid Mustafa, Ahmed Mohamed ULg; Saadi, Ismaïl ULg; Cools, Mario ULg et al

in Proceedings of GEOProcessing 2016 (2016, April 24)

Most existing spatio-temporal urban expansion models consider urban land-use as a binary process, through the identification of urban versus non-urban areas. The main aim of this study is to analyze and ... [more ▼]

Most existing spatio-temporal urban expansion models consider urban land-use as a binary process, through the identification of urban versus non-urban areas. The main aim of this study is to analyze and model the expansion of multiple urban densities in Wallonia, Belgium. To this end, this study employs a multinomial logistic regression model that enables to visualize the consequence of different urban densities expansion. Cadastral datasets of years 2000 and 2010 are used to set four urban classes (non-urban, low-density, medium-density and high-density urban). Besides, several socio-economic, geographic and political driving forces dealing with urban development were operationalized to create maps of urban expansion probability for each urban density class. These probability maps are then utilized to predict future urban expansions for years 2020 and 2030. The model is validated using relative operating characteristic method for different urban classes. Our results suggest that different urban densities expansions are mainly linked to zoning status, neighboring areas that are urban and accessibility. Most importantly, this study highlights that the contribution of different driving forces to urban expansion process varies along with urban density. [less ▲]

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See detailUsing NDACC column measurements of carbonyl sulfide to estimate its sources and sinks
Wang; Marshall, J; Palm, M et al

in Geophysical Research Abstracts (2016, April 19), 18

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See detailAbel inversion method for cometary atmospheres.
Hubert, Benoît ULg; Opitom, Cyrielle ULg; Hutsemekers, Damien ULg et al

in Geophysical Research Abstracts (2016, April 01), 18

Remote observation of cometary atmospheres produces a measurement of the cometary emissions integrated along the line of sight joining the observing instrument and the gas of the coma. This integration is ... [more ▼]

Remote observation of cometary atmospheres produces a measurement of the cometary emissions integrated along the line of sight joining the observing instrument and the gas of the coma. This integration is the so-called Abel transform of the local emission rate. We develop a method specifically adapted to the inversion of the Abel transform of cometary emissions, that retrieves the radial profile of the emission rate of any unabsorbed emission, under the hypothesis of spherical symmetry of the coma. The method uses weighted least squares fitting and analytical results. A Tikhonov regularization technique is applied to reduce the possible effects of noise and ill-conditioning, and standard error propagation techniques are implemented. Several theoretical tests of the inversion techniques are carried out to show its validity and robustness, and show that the method is only weakly dependent on any constant offset added to the data, which reduces the dependence of the retrieved emission rate on the background subtraction. We apply the method to observations of three different comets observed using the TRAPPIST instrument: 103P/ Hartley 2, F6/ Lemmon and A1/ Siding spring. We show that the method retrieves realistic emission rates, and that characteristic lengths and production rates can be derived from the emission rate for both CN and C2 molecules. We show that the emission rate derived from the observed flux of CN emission at 387 nm and from the C2 emission at 514.1 nm of comet Siding Spring both present an easily-identifiable shoulder that corresponds to the separation between pre- and post-outburst gas. As a general result, we show that diagnosing properties and features of the coma using the emission rate is easier than directly using the observed flux. We also determine the parameters of a Haser model fitting the inverted data and fitting the line-of-sight integrated observation, for which we provide the exact analytical expression of the line-of-sight integration of the Haser model. [less ▲]

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See detailEnglish translation and cross-cultural adaptation of the SarQuoL® questionnaire.
Beaudart, Charlotte ULg; Edwards, M.; Dennison, E.M. et al

in Osteoporosis International (2016, April), 27(Supplement 1), 221-222

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See detailOsteoarthritic sclerotic subchondral osteoblasts secreted elevated concentration of fibulin-3 fragments in vitro
Sanchez, Christelle ULg; Lambert, Cécile ULg; Comblain, Fanny ULg et al

in Osteoarthritis and Cartilage (2016, April), 24(suppl 1), 83

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See detailEfficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys.
Rannou, F.; Maheu; Reginster, Jean-Yves ULg

in Osteoporosis International (2016, April), 27(supplement 1), 66

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See detailReview of soluble biomarkers of osteoarthritis: lessons from animal model
Legrand, Catherine ULg; Lambert, Cécile ULg; Comblain, Fanny ULg et al

in Osteoarthritis and Cartilage (2016, April), 24(suppl 1), 88

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See detailPhysical and muscle performances among elderly nursing home residents.
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Croisier, Jean-Louis ULg et al

in Osteoporosis International (2016, April), 27(Supplement 1), 217

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See detailIs isokinetic exercise dangerous for the heart?
Le Goff, Caroline ULg; Kaux, Jean-François ULg; Cavalier, Etienne ULg et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(suppl. 1 No. 2), 457

INTRODUCTION: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in ... [more ▼]

INTRODUCTION: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in order to perform these very intensive exercises; otherwise an acute myocardial dysfunction could theoretically appear in predisposed patients. PURPOSE: Our study aimed to observe the cardiovascular impact (by biological point of view) of maximal intense isokinetic eccentric and concentric protocols performed by a population of sedentary young men. METHOD: Resting (T0) and post-exercise (just after (T1), 3 hours (T2) and 24 hours after the exercise (T3)) blood samples were taken in 2 populations of young sedentary men: 12 subjects (22.5±1.15 yo) for the eccentric protocol and 18 subjects (22.4±2.6 yo) for the concentric protocol. These subjects performed an intense maximal isokinetic exercise of the quadriceps muscles involving 30 knee flexions–extensions for each leg. We evaluated markers of cardiovascular risk (highly sensitive troponin T (hs-TnT), N-Terminal Brain natriuretic peptide (NT-proBNP), myoglobin (MYO)), of inflammation (highly sensitive C-reactive protein (hsCRP)), muscle damage (creatine kinase (CK)) and of oxidative stress (myeloperoxidase (MPO), lipidic peroxides (POXL), reduced (GSH) and oxidised glutathione (GSSG)). Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: All the physiological parameters measured presented statistically significant changes. For the eccentric exercise, no significant modification in cardiac (NT-proBNP, hs-TNT) and inflammation (hsCRP) biomarkers was observed. However, a significant increase for CK (T3), MYO (T2), MPO (T1), POXL (T1), GSSG (T3) and ratio GSH/GSSG (T2-T3) was shown. For the concentric exercise, the results showed significant increases for the CK (T1-T2-T3), MYO (T1-T2), GSH/GSSG (T1). Evolutionary trends were also observed for the following biomarkers: NT-proBNP (T1-T2-T3), MPO (T2), and GSSG (T4). DISCUSSION and CONCLUSIONS: No modification in cardiac biomarkers was observed after the maximal eccentric isokinetic exercise but some variations can be observed for these biomarkers after the concentric exercise. However, these changes do not exceed the reference values in healthy subjects. We were thus able to prove that the exercise could be performed without any risk to cardiac function in young sedentary subjects. Nevertheless, a significant level of oxidative stress was induced by both exercises. [less ▲]

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See detailEfficacy and safety of glucosamine sulfate in the management of osteoarthritis: Evidence from real-life setting trials and surveys.
Reginster, Jean-Yves ULg

in Osteoporosis International (2016, April), 27(supplement 1), 65

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See detailEffectiveness of High Intensity Radial Shock Wave Therapy in The Treatment of Chronic Plantar Fasciitis
Demoulin, Christophe ULg; Vanderthommen, Marc ULg; Fromm, Aurélien et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(Suppl. 1 No. 2), 733

Introduction: Literature is scarce concerning the effectiveness of high dose radial extracorporeal shock wave therapy (ESWT). Therefore, the aim of this study was to investigate its effectiveness on pain ... [more ▼]

Introduction: Literature is scarce concerning the effectiveness of high dose radial extracorporeal shock wave therapy (ESWT). Therefore, the aim of this study was to investigate its effectiveness on pain, function and pressure pain threshold in patients with chronicplantar fasciitis (PF). Materials and Methods: Patients with a diagnosis of chronic (pain lasting for more than 3 months) uni- or bilateral PF with a history of failed conservative treatment were included. After a 6-week control period during which no treatment occurred, a 2-week treatment period followed by a three weeks of rest (cicatrization phase) was provided. The treatment period consisted of three radial ESWT sessions (2000 impulses of 10 Hz frequency per session with an energy flux density of 0,275mJ/mm2) separated by a one-weekinterval. Patient assessments (pain intensity, foot function and pressure pain threshold (PPT) at the site of maximum local tenderness disability) were conducted at baseline, after the 6-week control phase (pre-treatment) and at the end of the cicatrization phase (post-treatment). Results: Thirty patients (19 women (63.3%)) with chronic PF and a mean age of 51.9±11 years were included in the present study. No drop-out occurred throughout the study period. No changes were observed at the pre-treatment assessment session except for pain intensity which decreased slightly but significantly (P<0.05). At the post-treatment session, highly significant (P<0.001) and clinically meaningful changes occurred for pain intensity (-34%), foot function score (-60%) and PPT (+68%). Conclusions: The present study suggests that high dose radial ESWT is a feasible and effective way to quickly and significantly decrease pain and disability in most patients with chronic PF. [less ▲]

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See detailThe future prevalence of sarcopenia in Europe
Ethgen, Olivier ULg; Tchoconte, C.; Beaudart, Charlotte ULg et al

in Osteoporosis International (2016, April), 27(Supplement 1), 53-54

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See detailPrevalence of concomitant bone and muscle wasting in patients from the SarcoPhAge study.
Locquet, Médéa ULg; Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg et al

in Osteoporosis International (2016, April), 27(supplement 1), 129

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See detailBrain-derived neurotrophic factor (BDNF) in normal healthy and hemodialyzed populations.
CAVALIER, Etienne ULg; CARLISI, Ignazia ULg; KOVACS, Stéphanie ULg et al

in Osteoporosis International (2016, April), 27(Supplement 1), 512

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See detailExploring the effect of a second closely-timed infiltration of platelet-rich plasma to treat proximal patellar tendinopathies
Kaux, Jean-François ULg; CROISIER, Jean-Louis ULg; FORTHOMME, Bénédicte ULg et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 54(Suppl. 1 No. 2), 199

Intorduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to ... [more ▼]

Intorduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of 2 or 3 successive infiltrations. Purpose: The aim of this study was to evaluate whether 2 infiltrations of PRP proves more effective than a single treatment. Methods: Twenty patients suffering from chronic jumper’s knee were enrolled into the study and split into two randomized groups (1 or 2 infiltrations of PRP, respectively). The 3-month follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. After 1 year, subjects were contacted to define their functional evolution. Results: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. Discussion and Conclusion: The comparison between 1 or 2 infiltrations of PRP did not reveal any difference between the 2 groups at short to mid term. A second closely-timed infiltration of PRP to treat jumper’s knees is not necessary to improve the efficacy of this treatment in the short term. A second infiltration should perhaps be envisaged later, but this remains to be demonstrated. [less ▲]

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See detailGood prognosis factors after a platelet rich plasma (PRP) injection for tendinopathies ?
Kaux, Jean-François ULg; Sancerne, Audrey; Libertiaux, Vincent ULg

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(suppl. 1 No. 2), 251

Introduction : Platelet-rich plasma injections are a recent treatment for chronic tendinopathies. However, this theraeutic remains controversed in litterature. Up to now, there is no prognosis factors ... [more ▼]

Introduction : Platelet-rich plasma injections are a recent treatment for chronic tendinopathies. However, this theraeutic remains controversed in litterature. Up to now, there is no prognosis factors identified to predict a good evolution after injection of PRP. Purpose: The aims of this study were to evaluate the effect of PRP injection followed by a standardized reeducation protocol among patients suffering from different tendinopathies and to determine the good prognosis factors, if any. Methods : 51 patients suffering from different tendinopathies and refractory to conventional physiotherapy were treated with a PRP injection. Prior to the injection, a blood sample was drawn and some biological parameters (glycemia, cholesterol level, …). A pain assessment was then made using a visual analog scale (VAS) and a pressure algometer. The same assessment was carried out after 6 weeks and 12 weeks when possible. Results : There is an overall significant improvement VAS score at the end of the 12 weeks follow- up. However, no correlation was found between the evolution of the clinical scores and the biological parameters measured. Discussion and Conclusions : A PRP injection followed by a program of eccentric rehabilitation positively affects the algo-functional scores of patients with tendinopathie who were refractory to conventional physiotherapy, whatever their initial biological parameters. [less ▲]

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See detailTen years of Denosumab (DMAB) treatment in postmenopausal women with osteoporosis. Results from the FREEDOM Extension trial.
Bone, H.G.; Brandi, M.L.; Brown, J.P. et al

in Osteoporosis International (2016, April), 27(Supplement 1), 135-136

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See detailMise au point d’une nouvelle méthode de diagnostic des allergènes du froment par Western blot 2D
BERTHOLET, Catherine ULg; GADISSEUR, Romy ULg; Quinting, Birgit

in Revue Française d'Allergologie (2016, April), 56(3), 284

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See detailMuscular and functional tridimensional analysis after hamstring strain
Paulus, Julien ULg; DELVAUX, François ULg; Schwartz, Cédric ULg et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(2), 263

Introduction The muscle injury, and more especially the hamstring strain, account for a large proportion of explosive top athletes injuries [1-3]. The subsequent down-time period has some sports and ... [more ▼]

Introduction The muscle injury, and more especially the hamstring strain, account for a large proportion of explosive top athletes injuries [1-3]. The subsequent down-time period has some sports and financial negatives consequences for the athlete, his team and/or his club [4, 5]. Despite the rehabilitation before return to play and prevention program, hamstring reinjury rates are still high (26% of all injuries) [6] and it's commonly accepted that a second injury is more severe than a first episode [2]. A more functional test could help the clinician in the return to play process decision to reduce the muscle injuries hamstring relapse. Purpose The aim of our methodology is to analyze, after medical clearance to resume sports activities, for athletes who suffered from grade II/III hamstring muscle strain, the biomechanics of the lower limbs during an explosive jump task. Method After (7,3±0,7 weeks) a grade II or III hamstring muscle tear, eight men (25±5,9 years), without past lower limb major injury, performed: - an isokinetic test (knee maximal flexion-extension in concentric at 60°.s-1 and 240°.s-1 and knee maximal flexion in eccentric at 30°.s-1); - a tridimensional biomechanics analysis of (bipodal and unipodal) squat jump and counter movement jump with Codamotion® system and Kistler® multicomponent force plates. Results A muscular lateral strength imbalance (±10% with p-value < 0,02) has been identified on the hamstring in concentric and eccentric by means of isokinetic testing, with the healthy side stronger than the pathologic. The main statistical significant outcome in the biomechanics analysis is the lower knee angle (±12% with p-value < 0,02) at the low point before the concentric pushing phase of the unipodal CMJ for the healthy leg than to the other one whereas there's no difference between both legs in an equivalent healthy population. Discussion & conclusion The tridimensional analysis appears to be complementary, not redundant, with the isokinetic strength testing due to the different nature of their informations obtained. It could be integrated in the return to play process decision expected the potentially interesting information about the player's biomechanics that it provides. References 1. Ekstrand, J., M. Hagglund, and M. Walden, Epidemiology of muscle injuries in professional football (soccer). Am J Sports Med, 2011. 39(6): p. 1226-32. 2. Ekstrand, J., M. Hagglund, and M. Walden, Injury incidence and injury patterns in professional football: the UEFA injury study. Br J Sports Med, 2011. 45(7): p. 553-8. 3. Lopez, V., Jr., et al., Profile of an American amateur rugby union sevens series. Am J Sports Med, 2012. 40(1): p. 179-84. 4. Price, R.J., et al., The Football Association medical research programme: an audit of injuries in academy youth football. Br J Sports Med, 2004. 38(4): p. 466-71. 5. Verrall, G.M., et al., Assessment of player performance following return to sport after hamstring muscle strain injury. J Sci Med Sport, 2006. 9(1-2): p. 87-90. 6. Brooks, J.H., et al., Incidence, risk, and prevention of hamstring muscle injuries in professional rugby union. Am J Sports Med, 2006. 34(8): p. 1297-306. [less ▲]

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See detailAge-standardized quality of life after hip or knee arthoplasty.
Neuprez, Audrey ULg; KURTH, William ULg; THIRION, Thierry ULg et al

in Osteoporosis International (2016, April), 27(Supplement 1), 541-542

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See detailPrevalence of frailty among nursing home, according to different operational definitions.
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; GILLAIN, Sophie ULg et al

in Osteoporosis International (2016, April), 27(Supplement 1), 216-217

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See detailA randomized double-blind study of Denosumab (DMAB) compared with Zoledronic acid (ZOL) in postmenopausal women with osteoporosis previously treated with oral bisphosphonates
Miller, P.; Pannacciulli, N.; Brown, J.P. et al

in Osteoporosis International (2016, April), 27(SUPPLEMENT1), 42

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See detailrelationship between total hip BMD T-score and incidence of nonvertebral fracture with up to 10 years of Denosumab (DMAB) treatment
Ferrari, S.; ADAMI, S.; Brown, J.P. et al

in Osteoporosis International (2016, April), 27(Supplement 1), 49-50

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See detailLight-to-moderate alcohol intake increases the risk of hepatocellular carcinoma in patients with HCV-related compensated cirrhosis: a prospective study.
Vandenbulcke, H; Moreno, C; Colle, I et al

in Acta Gastro-Enterologica Belgica (2016, March), 79(1), 01

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See detailAzacytidine Enhances Regulatory T-Cells In Vivo and Prevents Experimental Xenogeneic Graft-Versus-Host Disease
Ehx, Grégory ULg; Fransolet, Gilles ULg; de Leval, Laurence ULg et al

in Biology of Blood and Marrow Transplantation (2016, March), 22(3), 393

Background. The demethylating agent 5-azacytidine (AZA) has proven its efficacy as treatment for myelodysplastic syndrome and acute myeloid leukemia. In addition, AZA can demethylate FOXP3 intron 1 ... [more ▼]

Background. The demethylating agent 5-azacytidine (AZA) has proven its efficacy as treatment for myelodysplastic syndrome and acute myeloid leukemia. In addition, AZA can demethylate FOXP3 intron 1 (FOXP3i1) leading to the generation of regulatory T cells (Tregs). Objective. We investigated the impact of AZA on xenogeneic graft-versus-host disease (xGVHD) in a humanized murine model of transplantation, and described the impact of the drug on human T cells in vivo. Methods. In order to induce xGVHD, human peripheral blood mononuclear cells (huPBMC) were administered intravenously in NOD-scid IL-2Rγnull (NSG) mice. Results. AZA successfully improved both survival (p<0.0001) and xGVHD scores (p<0.0001). Further, AZA significantly decreased human T-cell proliferation as well as INF-γ and TNF-α serum levels, and reduced the expression of GRANZYME B and PERFORIN 1 by cytotoxic T cells. In addition, AZA administration significantly increased the function, proliferation and frequency of Tregs through demethylation of FOXP3i1 and higher secretion of IL-2 by conventional T cells due to IL2 gene promoter site 1 demethylation. Interestingly, among AZA-treated mice surviving the acute phase of xGVHD, there was an inverse correlation between the presence of Tregs and signs of chronic GVHD. Finally, Tregs harvested from the spleen of AZA-treated mice were suppressive and stable over time since they persisted at high frequency in secondary transplant experiments. Conclusion. These findings emphasize a potential role for AZA as prevention or treatment of GVHD and other autoimmune diseases. [less ▲]

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See detailSofosbuvir in combination with simeprevir +/- ribavirin in genotype 4 hepatitis C patients with advanced fibrosis or cirrhosis: real-life experience from Belgium
Moreno, C; Lasser, L; DELWAIDE, Jean ULg et al

in Acta Gastro-Enterologica Belgica (2016, March), 79(1), 08

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See detailGenetics 2 Multiple fractures, genetics to the rescue!
HENNUY, Nadège ULg; NYAMUGABO MUNYERE NKANA, Kindja ULg; FLORKIN, Benoît ULg et al

in Belgian Journal of Paediatrics (2016, March), 18(1), 63

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See detailDiscovery of novel accessible proteins for therapeutic targeting of hepatocellular carcinoma.
Turtoi, Andrei ULg; Otaka, Y; Rokudai, S et al

in Acta Gastro-Enterologica Belgica (2016, March), 79(1), 13

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See detailNewborn screening for sickle cell disease : 13 years at the CHR "La Citadelle", Liège
Sepulchre, Edith; Ketelslegers, Olivier; Minon, Jean-Marc et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2016, March), 18(1), 107

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See detailChattering-free Sliding Mode Control for Propellantless Rendez-vous using Differential Drag
Cho, Hancheol ULg; Dell'Elce, Lamberto ULg; Kerschen, Gaëtan ULg

in International Conference on Astrodynamics Tools and Techniques (2016, March)

This paper develops a differential drag-based sliding mode controller for satellite rendez-vous. It is chattering-free and avoids bang-bang type control to adjust the relative motion more efficiently. In ... [more ▼]

This paper develops a differential drag-based sliding mode controller for satellite rendez-vous. It is chattering-free and avoids bang-bang type control to adjust the relative motion more efficiently. In spite of uncertain nonlinear perturbations and disturbances, it is shown that the in-plane relative motion between two satellites can be effectively controlled by regulating the drag difference. An adaptive tuning rule is also presented such that the errors are suppressed to lie within a desired error box. The proposed controller is simple and easy to implement in a small satellite, and numerical simulations are carried out to demonstrate its effectiveness in a high fidelity environment. [less ▲]

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See detailBois, brique et fer : Approche multi-disciplinaire de la charpente de l'église Notre-Dame du Sablon, Bruxelles (RBC)
CREMER, Sarah; FRAITURE, Pascale; Hoffsummer, Patrick ULg et al

in Archaeologia Mediaevalis (2016, March), 39

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See detailMulticenter Belgian experience of sofosbuvir medical need program in pre-and post-liver transplantation patients: safety and efficacy results.
Degré, D; Laleman, W; Verhelst, X et al

in Acta Gastro-Enterologica Belgica (2016, March), 79(1), 15

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See detailLINKING CATTLE GRAZING BEHAVIOR TO METHANE AND CARBON DIOXIDE DYNAMICS
Blaise, Yannick ULg; Lebeau, Frédéric ULg; Andriamandroso, Andriamasinoro ULg et al

in Communications in Agricultural and Applied Biological Sciences (2016, February), 81(1), 107-112

Various methods are presently used to measure methane (CH4) emissions of ruminants on pasture. Those measurements are essential to evaluate nutritional strategies to mitigate enteric CH4 emissions as well ... [more ▼]

Various methods are presently used to measure methane (CH4) emissions of ruminants on pasture. Those measurements are essential to evaluate nutritional strategies to mitigate enteric CH4 emissions as well as addressing the selection of low producing individuals. On pasture and in the barn, variations in CH4 emissions are observed depending on the time of the day. However, no studies have been made to link these diurnal fluctuations to behavioural phases, especially on pasture. The aim of this study was to understand the individual dynamics of CH4 production and their links to the grazing behaviour. For this purpose, a new tool was specifically developed. Five red-pied dry cows were equipped with infrared CH4 and carbon dioxide (CO2) sensors measuring concentrations in the exhaled air at 4 Hz. The animals were equipped with a heart rate belt (HR) and motion sensors to detect their feeding behaviours (grazing vs. rumination) for periods of 8 h/d. Wind speed (WS) was also monitor to verify interference with sampled gas concentrations. Results showed that using the CH4:CO2 ratio reduced the interference with WS that was observed on raw CH4 and CO2 concentration signals. CH4:CO2 ratio average over 5 min periods indicated that CH4 emissions were lower during grazing than rumination (P<0.01). The eructation frequency during grazing (0.48 eructation/min, P<0.01) was also lower than during rumination (0.65 eructation/min). HR was higher during grazing that rumination. Because HR is usually linked to metabolic CO2 production intensity, hence influencing the denominator of the CH4:CO2 ratio, further investigation should focus on the quantification of changes in fermentative and metabolic CO2 emissions along the day to estimate total CH4 production more accurately and the relationship between CH4 emissions patterns and post-feeding times. [less ▲]

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See detailSuivi de quelques mammifères protégés en Wallonie.
Schockert, Vincianne ULg; Lambinet, Clotilde ULg; Libois, Roland ULg

in FORÊT.NATURE (2016, February), 138

Depuis 2005, la "convention Mammifères" qui lie le SPW et l'U.Lg a pour but d'actualiser les connaissances sur les petits mammifères non volants en Wallonie: distribution et (micro-) habitats utilisés ... [more ▼]

Depuis 2005, la "convention Mammifères" qui lie le SPW et l'U.Lg a pour but d'actualiser les connaissances sur les petits mammifères non volants en Wallonie: distribution et (micro-) habitats utilisés. Ces 30 dernières années, quelques mesures ont eu un impact sur les populations: mise sous statut de protection, renforcement général de la règlementation environnementale (Natura 2000, code forestier...) et épizooties. Quelques exemples montrent la diversité et la spécificité des suivis nécessaires en vue d'évaluer leur état de conservation: cinq espèces de musaraignes protégées, la loutre, la martre, le muscardin et le blaireau. Pour ce dernier, la comparaison des niveaux de population et de dégâts de l'année 2012 démontre l'importance de disposer de données solides sur les populations pour éviter une révision inappropriée de leur statut [less ▲]

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See detailOverview of Superhydrophilic, Photocatalytic and Anticorrosive Properties of TiO2 Thin Films Doped with Multi-walled Carbon Nanotubes and Deposited on 316L Stainless Steel
Léonard, Géraldine ULg; Remy, Simon; Heinrichs, Benoît ULg

in Materials Today: Proceedings (2016, February), 3(2), 434-438

TiO2 films with MWCNTs are produced for anticorrosive applications to increase the lifetime of steel materials. TiO2 has two additional properties, photoactivity and superhydrophilicity. Two TiO2 samples ... [more ▼]

TiO2 films with MWCNTs are produced for anticorrosive applications to increase the lifetime of steel materials. TiO2 has two additional properties, photoactivity and superhydrophilicity. Two TiO2 samples, synthesized in aqueous or alcoholic media, have been doped with MWCNTs. The material which best combines anticorrosive, superhydrophilic and photocatalytic properties, is the one produced in aqueous medium (Aq-TiO2-CNT). Doping with MWCNTs increases the photodegradation of p-nitrophenol from 18% to 50%. MWCNTs allow to reduce the corrosion current and the corrosion potential. The good superhydrophilicity of TiO2 is kept on stainless steel with a contact angle after illumination around 5°. [less ▲]

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See detailComputed Tomography and Magnetic Resonance Findings in Athletes at Risk for Sudden Cardiac Death
Ghekiere, Olivier; Nchimi Longang, Alain ULg; Bijnens, Eric et al

in Journal of the Belgian Society of Radiology (2016, February), 1

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See detailTrophic diversity of seagrass detritus copepods: A consequence of species-specific specialization or a random diet?
Mascart, Thibaud; De Troch, Marleen; Remy, François ULg et al

in PeerJ PrePrints (2016, January 13), 4

One of the major ecological research questions is understanding how biodiversity influences ecosystem functioning. Unravelling interspecific feeding preferences of organisms with overlapping trophic ... [more ▼]

One of the major ecological research questions is understanding how biodiversity influences ecosystem functioning. Unravelling interspecific feeding preferences of organisms with overlapping trophic niches will give part of the answer. Subsequently, the present study displays the trophic diversity of a benthic copepod community in a North-Western Corsican Posidonia oceanica seagrass ecosystem. These seagrass meadows are often interrupted by bare sand patches serving as deposition area for loose detritus. The accumulated macrophytodetritus, mainly derived from senescent macrophytes, harbour a diverse community of Harpacticoida (Crustacea, Copepoda). The most abundant copepods (i.e. three harpacticoids and one calanoid, belonging to different eco-morphological types) and their potential food sources (i.e. macrophytodetritus, epiphytic biofilm and suspended organic matter) were analysed for stable isotope ratios (δ13C, δ15N) and total lipids content. The results revealed a harpacticoid copepod feeding preference towards the epiphytic biofilm, while calanoid copepods preferred suspended organic matter. Additionally, a species-specific composition variation revealed finer partitioning of food resources (e.g. different micro-organisms present in the biofilm like bacteria, diatoms, fungi) over time.In conclusion, results showed species-specific food preferences, resulting in trophic niche and resource partitioning. Every eco-morphological type seems to cope in different ways with temporal fluctuations of food sources to comply with their nutritional needs. This illustrates the high resilience of the copepod community present in macrophytodetritus accumulations. Moreover, our results underlined the importance of multiple biomarker species-specific analysis in trophic ecology studies, especially in complex and dynamic environments offering numerous food items to consumers. [less ▲]

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See detailProjet Neworld: Evaluation informatisée des capacités de multitâches en neuropsychiatrie
Laloyaux, Julien ULg; Van Der Linden, M; Levaux, M-N et al

in Encéphale (L') (2016)

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See detailConclusions des journées d’étude "Cher Monsieur Madrane"
Fierens, Jacques ULg

in Journal du Droit des Jeunes (2016), 354

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See detailApports de l'électrophysiologie à la médecine d'expertise
WANG, François-Charles ULg

in Consilio manuque (2016), 1

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See detailStudy of the Potential Zoonotic Transmission of Clostridium difficile in Belgian Cattle Farms.
Rodriguez Diaz, Cristina ULg; Hakimi, Djalal-Eddine; Daube, Georges ULg et al

in Journal of Food Protection (2016), 79(supplement A),

Introduction: Zoonoses are infectious that can be transmitted between animals and humans through direct contact, close proximity or the environment. Since domestic and food animals frequently test ... [more ▼]

Introduction: Zoonoses are infectious that can be transmitted between animals and humans through direct contact, close proximity or the environment. Since domestic and food animals frequently test positive for the bacterium, it seems plausible that C. difficile could be zoonotic. A former study showed that the prevalence in veal calf aged less than 6 months was 22% while in adult cattle population, it was 6,9 %. Purpose: This study aimed to determine the prevalence and the epidemiology of C. difficile in cattle farms and the possible spread of the bacterium among animals and farmers. Methods: A total of 176 faecal samples of cattle were collected from 5 different Belgian farms (south East Belgium), from November 2015 to February 2016. A stool sample of each farmer was also requested. Detection of C. difficile was performed by classical culture on C. difficile selective medium (cycloserine cefoxitin fructose cholate). Isolates were characterised by PCR-ribotyping and Genotype Cdiff test (Hain Lifescience), which allows the detection of all toxin genes, mutations in gyrA gene and the deletion in the regulator gene tcdC. Toxic activity was confirmed by a cytotoxic assay on MRC-5 cells. Results: C. difficile was detected in 14/178 (7.9%) animal samples. Isolates were grouped into five different types, including PCR-ribotype 015 (this ribotype is one the most encountered in hospitals in Belgium). The other types were UCL46A, UCL24*, UCL24, UCL33. All of them were identified as toxigenic by cytotoxicity assay and toxin genes profile. In contrast, none of the 5 farmers studied were positive for the bacterium. Significance: Results obtained indicate that PCR-ribotypes commonly isolated from hospitalised patients are also present in cattle, indicating an animal reservoir. However, a zoonotic transmission could be not demonstrated in this preliminary study. [less ▲]

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See detailEpisodic memory and aging: The effect of perceptual processing fluency on recognition memory processes
Bastin, Christine ULg; Willems, Sylvie ULg

in Journal of Cognitive Neuroscience (2016), S2016

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See detailSclérostine & insuffisance rénale: que nous apprennent les différents méthodes de dosage?
PAQUOT, Francois ULg; BOUQUEGNEAU, Antoine ULg; CAVALIER, Etienne ULg et al

in Néphrologie & Thérapeutique (2016), 12(5), 374

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See detailEn-deçà du langage : Communauté et historicité de l’antéprédicatif selon Heidegger
Zincq, Aurélien ULg

in Bulletin d'Analyse Phénoménologique (2016), XII(2), 251-274

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See detailAssociation between vertebral heart score measurement and overweight condition in dogs
François, Marion; Merveille, Anne-Christine ULg; Mc Entee, Kathleen ULg et al

in Veterinary Radiology & Ultrasound (2016)

Introduction Vertebral heart score (VHS) is used to assess heart size on thoracic radiographs. Association between VHS and overweight condition in dogs of different breeds is still unknown. The aim of ... [more ▼]

Introduction Vertebral heart score (VHS) is used to assess heart size on thoracic radiographs. Association between VHS and overweight condition in dogs of different breeds is still unknown. The aim of this study is to determine if VHS is influenced by overweight condition in dogs. The hypothesis is that VHS is influenced by BCS and T4 ratio. Methods Recruitment criteria for this retrospective study were the presence of a minimum of 2 thoracic radiographic views and a diagnosis of “normal echocardiographic examination” in medical records from 2013 to 2016. Body weight, BCS and breed were extracted. VHS and overweight condition were calculated. Dogs from breeds with a normal maximal VHS < 11 (group 1) and from breeds with a normal maximal VHS > 11 (group 2) were separated. Statistical analyses were performed using XLStat® software. Results Fifty-one dogs were included in the study. Body weight ranged from 3.7 to 44.8 kg and was not recorded in 2 dogs. These dogs were not excluded because of the BCS was recorded for these dogs. BCS ranged from 3 to 9. Thirteen dogs had a VHS value superior to the normal range and all of them had BCS ≥ 4. A weak positive correlation was found between BCS and T4 ratio (P ≤ 0.001, R2=0.4). There was a positive relationship between BCS and VHS (ANCOVA, P ≤ 0.003) for each group and between T4 ratio and VHS for each group (ANCOVA, P ≤ 0.001). Discussion/Conclusions This study confirms that the T4 ratio is correlated to BCS evaluated clinically. This ratio could be used to assess overweight condition on thoracic radiographs. VHS is influenced by BCS and the T4 ratio; therefore, VHS should be use with caution in overweighed dogs. [less ▲]

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See detailGeomorphometric mapping of spatio-temporal changes in Plio-Quaternary uplift in the NW European Alpine foreland
Demoulin, Alain ULg; Bourdon, Hadrien

in Geophysical Research Abstracts (2016), 18

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See detailCircadian and homeostatic sleep pressure modulate fMRI correlates of vigilant attention
Muto, Vincenzo ULg; Jaspar, Mathieu ULg; Meyer, C et al

in Journal of Sleep Research (2016), 25(s1),

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See detailPrevalence of vasculare risk factors in different stages of prodromal Alzheimer’s disease and its influence on cognitive decline
Bos, I.; Vos, S.; Frölich, L. et al

in Alzheimer's & Dementia : The Journal of the Alzheimer's Association (2016), 12(7), 1059-1061

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See detailPrevalence of frailty among nursing home, according to different operational definitions
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; GILLAIN, Sophie ULg et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 69

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See detailPrevalence of concomitant bone and muscle wasting in patients from the SarcoPhAge Study
Locquet, Médéa ULg; Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 84

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See detailBrain-derived neurotrophic factor (BDNF) in normal healthy and hemodialyzed populations
CAVALIER, Etienne ULg; Carlisi, A.S.; WATAR, Florence ULg et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 116

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See detailImplementation of the green payment within the scheme of the new Common Agricultural Policy (2015-2020): first results for 2015 in Wallonia (South of Belgium)
Burny, Philippe ULg; Terrones Gavira, François ULg

in Quality-Access to Success (2016), (Supplement), 10-14

At the end of 2013, a new Common Agricultural Policy was defined at the European level, including the implementation of the so-called “green payment”, which obliges farmers to respect three new conditions ... [more ▼]

At the end of 2013, a new Common Agricultural Policy was defined at the European level, including the implementation of the so-called “green payment”, which obliges farmers to respect three new conditions in order to get financial support through direct payments. The year 2015 being the first implementation year, the consequences on Walloon agriculture are examined. It appears that 50% of Walloon farmers are not obliged to practice crop diversification, while 16% are obliged to have at least two crops on their arable land and 33% are obliged to have at least three crops on their arable land. Less than 1% does not respect the new diversification rules. Concerning the obligation to have at least 5% of ecological focus area on the arable land, it appears that 54% of Walloon farmers are in conditions not to be obliged to respect the measure. When they implement the measure, the percentage of ecological focus areas in arable land reaches 6.9% as a mean and 2.4% do not reach the requested 5%. Finally, it can be said that the green payment does not represent a big constraint for Walloon farmers, though eventual economic consequences are still to be precised, while environmental benefits are strengthened. [less ▲]

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See detailPsychometric properties of the Questionnaire of Executive Self-Awareness (QESA) for Children
Geurten, Marie ULg; Catale, Corinne ULg; Geurten, Claire ULg et al

in Journal of the International Neuropsychological Society (2016)

Objective: People with accurate representations of their own cognitive functioning (i.e., cognitive self-awareness) tend to use appropriate strategies to regulate their behavior. Due to the lack of ... [more ▼]

Objective: People with accurate representations of their own cognitive functioning (i.e., cognitive self-awareness) tend to use appropriate strategies to regulate their behavior. Due to the lack of appropriate instruments, few studies have examined the development of this ability among children. Method: This study tested the measurement properties of the self-rating and other-rating forms of the Questionnaire of Executive Self-Awareness (QESA), designed to tap children’s knowledge of their executive functioning. Participants were 317 children aged 7 to 14 years old. Results: Confirmatory factor analyses carried out on the QESA confirmed the eight-factor structure of both versions. There were significant correlations between the QESA and the parent versions of the BRIEF, DEX-C, and CHEXI. Both forms of the QESA were able to distinguish between children who had sustained a traumatic brain injury (TBI) and control participants. A self-other discrepancy score was computed to assess children’s executive self-awareness. A statistical difference was observed between the TBI and control groups on this score, suggesting that TBI may trigger self-awareness impairments in children. Conclusion: The good psychometric properties of the two forms of the QESA were established. Furthermore, results of the analyses carried on the different discrepancy scores seem to indicate that the QESA could help clinicians to detect patients with self-awareness deficits. [less ▲]

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See detailEnglish translation and cross-cultural adaptation of the SARQOL Questionnaire
Beaudart, Charlotte ULg; Edwards, M.; Dennisson, E. et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 58

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See detailVolumetric brain MRI measurements in a retrospective Belgian multi-centr MRI biomarker study in dementia - REMEMBER
Niemantsverdriet; Smeets, D.; Bastin, Christine ULg et al

in Acta Neurologica Belgica (2016)

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See detailNumerical prediction of ductile failure in the blanking process by means of uncoupled and coupled phenomenological damage models
Canales Cardenas, Cristian ULg; Ponthot, Jean-Philippe ULg

in MATEC Web of Conferences (2016)

Fracture prediction in blanking has gained great attention due to increasing requirements of high-quality products. In this work, the predictive capabilities of different uncoupled and coupled damage ... [more ▼]

Fracture prediction in blanking has gained great attention due to increasing requirements of high-quality products. In this work, the predictive capabilities of different uncoupled and coupled damage models, recently implemented in a fully implicit homemade FE code, for blanking process are compared. Some advanced models considered here include damage sensitivity to both triaxiality and Lode angle in their formulation. The material characterization is based on the history of internal variables during loading, where different mechanical tests are considered. Finally, numerical and experimental results are compared for a wide range of different geometries of blanking. [less ▲]

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See detailUrban infrastructure resilience to fire disaster: An overview
Gernay, Thomas ULg; Selamet, Serdar; Tondini, Nicola et al

in Procedia Engineering (2016), 161C

Fire disasters are a serious threat to the functionality of the built environment, in particular in densely populated urban areas where city infrastructure systems are under strain. Yet, fire safety ... [more ▼]

Fire disasters are a serious threat to the functionality of the built environment, in particular in densely populated urban areas where city infrastructure systems are under strain. Yet, fire safety issues are still mostly considered at the level of individual elements or buildings, disregarding the global risk for systems’ functionality. In line with the current efforts toward ensuring more resilient cities, this paper presents an overview of urban infrastructure resilience to fire disaster. The definitions of resilience and the quantitative frameworks established for other hazards such as earthquakes are reviewed. Then, the specificities of structural fire engineering are presented and it is shown how resilience frameworks could be applied to fire hazard. Finally, the paper identifies areas where further research efforts are needed. [less ▲]

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See detailSofosbuvir + simeprevir +/-ribavirin treatment is efficient in genotype 4 chronic hepatitis C patients: results of a large international cohort.
Moreno, C; Derbala, M; Nguyen-Khac, E et al

in Hepatology (Baltimore, Md.) (2016), 64(1), 1990

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See detailInfluence of crossed fields in structures combining large grain, bulk (RE)BCO superconductors and soft ferromagnetic discs
Philippe, Matthieu ULg; Fagnard, Jean-François ULg; Wera, Laurent ULg et al

in Journal of Physics: Conference Series (2016), 695

Bulk (RE)BCO superconductors are able to trap record magnetic fields and can be used as powerful permanent magnets in various engineering applications such as rotating machines and magnetic bearings. When ... [more ▼]

Bulk (RE)BCO superconductors are able to trap record magnetic fields and can be used as powerful permanent magnets in various engineering applications such as rotating machines and magnetic bearings. When such superconducting (SC) “trapped field magnets” are combined to a ferromagnetic (FM) disc, the total magnetic moment is increased with respect to that of the superconductor alone. In the present work, we study experimentally the magnetic behaviour of such hybrid FM/SC structures when they are subjected to cycles of applied field that are orthogonal to their permanent magnetization, i.e. a “crossed-field” configuration. Experimental results show that the usual “crossed-field demagnetization” caused by the cycles of transverse field is strongly reduced in the presence of the ferromagnet. [less ▲]

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See detailThe effect of napping on the consolidation of explicit and implicit information
van Schalkwijk, F J; Heib, D P J; Hoedlmoser, K et al

in Journal of Sleep Research (2016), 25(s1),

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See detailIdentification and characterization of volatile organic compounds active against barley pathogens
De Clerck, Caroline ULg; Kaddes, Amine ULg; Fiers, Marie et al

in Bulletin OILB/SROP = IOBC/WPRS Bulletin (2016), 117

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See detailGERONTECHNOLY IN WALLONIA
PETERMANS, Jean ULg; LEJEUNE, CHRISTOPHE; MAERTENS, Fulvie ULg et al

in Gerontechnology (2016), 15

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See detailPulsations in hot subdwarf stars: recent advances and prospects for testing stellar physics
Charpinet, Stéphane; Van Grootel, Valérie ULg; Fontaine, G. et al

in Proceedings of the International Astronomical Union (2016), 29

The evolved, core helium burning, extreme horizontal branch stars (also known as hot B subdwarfs) host several classes of pulsators showing either p- or g-modes, or both. They offer particularly favorable ... [more ▼]

The evolved, core helium burning, extreme horizontal branch stars (also known as hot B subdwarfs) host several classes of pulsators showing either p- or g-modes, or both. They offer particularly favorable conditions for probing with asteroseismology their internal structure, thus constituting arguably the most interesting seismic window for this intermediate stage of stellar evolution. G-modes in particular have the power to probe deep inside these stars, down to the convective He-burning core boundary where uncertain physics (convection, overshooting, semi-convection) is at work. Space data recently obtained with CoRoT and Kepler are offering us the possibility to probe these regions in detail and possibly shed new light on how these processes shape the core structure. In this short paper, we present the most recent advances that have taken place in this field and we provide hints of the foreseen future achievements of hot subdwarf asteroseismology. [less ▲]

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See detailOptical characterization of Sol-Gel ZnO:Al thin films
Ivanova, T; Harizanova, A; Koutzarova, T et al

in Journal of Physics: Conference Series (2016), 700

This paper presents a sol-gel technological process for preparing thin films of ZnO and ZnO:Al. The effect of annealing treatments (500, 600, 700 and 800 oC) on their properties was studied. The ... [more ▼]

This paper presents a sol-gel technological process for preparing thin films of ZnO and ZnO:Al. The effect of annealing treatments (500, 600, 700 and 800 oC) on their properties was studied. The structural evolution with the temperature was investigated by using X-Ray diffraction (XRD). Fourier Transform Infrared (FTIR) and UV-VIS spectrophotometry were applied to characterizing the films’ vibrational and optical properties. The ZnO and ZnO:Al films possessed a polycrystalline structure. The films studied are highly transparent in the visible spectral range. The optical band gap values and the haze parameter were also determined. [less ▲]

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See detailEnquêter sur les non-publics de la culture: quelle posture de recherche pour quel dispositif méthodologique?
Ghebaur, Cosmina ULg

in Questions de Communication (2016)

Mes travaux portent sur les non-publics de la culture et leur fabrication institutionnelle, à savoir leur production par les institutions chargées de mettre en œuvre sur un territoire donné les politiques ... [more ▼]

Mes travaux portent sur les non-publics de la culture et leur fabrication institutionnelle, à savoir leur production par les institutions chargées de mettre en œuvre sur un territoire donné les politiques culturelles les concernant. Pour explorer cette question, je me place dans la perspective initiée en sociologie de l'art par Pascale Ancel et Alain Pessin (2004) et caractérisée par la remise en question de la frontière entre publics et non-publics. On peut, écrit Martine Azam (2004), être " à la fois " public et non-public s'agissant de deux objets culturels différents ou du même objet à des moments différents. L'objectif de cet article est d'expliciter les principaux choix méthodologiques que j'ai été amenée à faire en enquêtant, avec cette posture de recherche, sur une exposition photographique en extérieur organisée dans une ville de la banlieue parisienne. [less ▲]

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See detailDiffusion MRI for following tumor modifications after neoadjuvant radiotherapy.
LALLEMAND, François ULg; Leroi, Natacha ULg; Bahri, Mohamed Ali ULg et al

in Radiotherapy & Oncology (2016), 119

Neoadjuvant radiotherapy (NeoRT) improves tumor local control and tumor resection in many cancers. The timing between the end of the NeoRT and surgery is driven by the occurrence of side effects or the ... [more ▼]

Neoadjuvant radiotherapy (NeoRT) improves tumor local control and tumor resection in many cancers. The timing between the end of the NeoRT and surgery is driven by the occurrence of side effects or the tumor downsizing. Some studies demonstrated that the timing of surgery and the RT schedule could influence tumor dissemination and subsequently patient overall survival. We demonstrated the impact of NeoRT on metastatic spreading in a Scid mice model. After an irradiation of 2x5gy, we show more metastasis in the lung when the mice are operated at day 4 compared to day 11. Here, our aim is to evaluate with functional MRI (fMRI) the impact of the radiation treatment on the tumor microenvironment and subsequently to identify non-invasive markers helping to determine the best timing to perform surgery for avoiding tumor spreading. [less ▲]

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See detailA no-go theorem for the dark matter interpretation of the positron anomaly
Laletin, Maxim ULg

in Frascati Physics Series (2016), LXIII

The overabundance of high-energy cosmic positrons, observed by PAMELA and AMS-02, can be considered as the consequence of dark matter decays or annihilations. We show that recent FERMI/LAT measurements of ... [more ▼]

The overabundance of high-energy cosmic positrons, observed by PAMELA and AMS-02, can be considered as the consequence of dark matter decays or annihilations. We show that recent FERMI/LAT measurements of the isotropic diffuse gamma-ray background impose severe constraints on dark matter explanations and make them practically inconsistent. [less ▲]

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See detailGeological evidence for Holocene earthquakes and tsunamis along the Nankai-Suruga Trough, Japan
Garett, Ed; Fujiwara, Osamu; Garrett, Philip et al

in Geophysical Research Abstracts (2016)

The Nankai-Suruga Trough, lying immediately south of Japan’s densely populated and highly industrialised southern coastline, generates devastating great earthquakes (magnitude > 8). Intense shaking ... [more ▼]

The Nankai-Suruga Trough, lying immediately south of Japan’s densely populated and highly industrialised southern coastline, generates devastating great earthquakes (magnitude > 8). Intense shaking, crustal deformation and tsunami generation accompany these ruptures. Forecasting the hazards associated with future earthquakes along this >700 km long fault requires a comprehensive understanding of past fault behaviour. While the region benefits from a long and detailed historical record, palaeoseismology has the potential to provide a longer-term perspective and additional insights. Here, we summarise the current state of knowledge regarding geological evidence for past earthquakes and tsunamis, incorporating literature originally published in both Japanese and English. This evidence comes from a wide variety of sources, including uplifted marine terraces and biota, marine and lacustrine turbidites, liquefaction features, subsided marshes and tsunami deposits in coastal lakes and lowlands. We enhance available results with new age modelling approaches. While publications describe proposed evidence from > 70 sites, only a limited number provide compelling, well-dated evidence. The best available records allow us to map the most likely rupture zones of eleven earthquakes occurring during the historical period. Our spatiotemporal compilation suggests the AD 1707 earthquake ruptured almost the full length of the subduction zone and that earthquakes in AD 1361 and 684 were predecessors of similar magnitude. Intervening earthquakes were of lesser magnitude, highlighting variability in rupture mode. Recurrence intervals for ruptures of the a single seismic segment range from less than 100 to more than 450 years during the historical period. Over longer timescales, palaeoseismic evidence suggests intervals ranging from 100 to 700 years. However, these figures reflect thresholds of evidence creation and preservation as well as genuine recurrence intervals. At present, we have not identified any geological data that support the occurrence earthquakes of larger magnitude than that experienced in AD 1707; however, few published studies seek to establish the relative magnitudes of different earthquake and tsunami events. Alongside the paucity of research designed to quantify the magnitude of past earthquakes, we emphasise a number of other issues, including alternative hypotheses for proposed palaeoseismic evidence, the lack of robust chronological frameworks and insufficient appreciation of changing thresholds of evidence creation and preservation over time. These key issues must be addressed by future research. [less ▲]

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See detailDo the elderly feel older after exposure to negative aging stereotypes?
Marquet, Manon ULg; Missotten, Pierre ULg; Adam, Stéphane ULg

in International Psychogeriatrics (2016), 27(Supplement 1), 70-172

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See detailAgeism among nurses in oncology
Schroyen, Sarah ULg; Missotten, Pierre ULg; Jerusalem, Guy ULg et al

in International Psychogeriatrics (2016)

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See detailLast millennium gravity reworking processes in the western Gulf of Corinth: correlations with historical seismicity and indication of earthquake clusters
Beckers, Arnaud; Beck, Christian; Hubert, Aurelia ULg et al

in Geophysical Research Abstracts (2016), 18

The western tip of the Corinth Rift is considered as the most active within this major extensional structure, as evidenced by: seismicity, GPS kinematics, and INSAR data (Bernard et al., 2006). Within the ... [more ▼]

The western tip of the Corinth Rift is considered as the most active within this major extensional structure, as evidenced by: seismicity, GPS kinematics, and INSAR data (Bernard et al., 2006). Within the frame of a multidisciplinary project dedicated to seismic hazards assessment for this region, two offshore surveys - high resolution seismic reflection and gravity coring - were conducted in this area. They were dedicated to the Late Quaternary sedimentary fill as the latter was expected to record both long term deformation (Beckers et al., 2015) and sedimentary “events” related to major earthquakes and/or tsunamis. Seismic reflection imaging displays the time and geographical distributions of large submarine landslides (MTDs) during the last 100 kyr. Based on a morpho-sedimentary map and the active fault pattern, up to 2 m-long cores were selected to detect and characterise the possible impact of historical events. The chronological control is based on AMS 14C dating and four detailed 210Pb and 137Cs profiles. Sedimentation (components, sources, transport and settling mechanisms) was analysed through textural, chemical, and mineralogical parameters. Turbidites could be clearly separated from the hemipelagic deposits. Our attempt to correlate identified sedimentary “events” with historical data greatly benefited from a recently elaborated catalog (Albini et al., 2014) with precisely re-located epicentral areas. Cable breaks were also taken into account. Attenuation models (Papazachos & Papaioannou’s, 1997) were used to discuss paleo-intensities vs. distance form epicentral areas. From the whole set of cores, the following results may be underlined: - the correlations between cores from the different sites are not complete, including for a few neighbouring sites belonging to the same morpho-sedimentary unit; we relate these discrepancies to the complex bottom morphology and/or to bottom currents responsible for local erosion; - for several well-documented earthquakes and tsunamis, we could not find a clearly recorded sedimentary impact; - non earthquake-triggered MTDs (as the 1963 event) produced specific layers identical to the major earthquakes impacts. At the difference, for a few cores from the deep axial floor, several sandy or silty turbidites permit to establish correlations: i) between coring sites, ii) with earthquakes which stroke two different areas, respectively east and west of the concerned part of the Gulf. Furthermore, the sedimentary events show a particular time distribution for the last 600 yr: - two intervals with short recurrences: a recent one ( 1900 AD-Present or 1750 AD-Present) and an older one ( 1550 AD-1700 AD or 1450 AD-1800 AD); these time distributions differ from each coring site; - a long “quiet” period (150 to 200 yr). From these results, we tentatively consider this sedimentary record as an indicator of a migration of seismogenic faulting activity. Ref.: Albini, P., et al., 2014. Techn. Rep. I.N.G.V. Roma. Beckers, A., et al., 2015. Marine Geology, 360:55–69 Bernard, P., et al., 2006. Tectonophysics, 426:7-30. Papazachos, C., Papaioannou, C., 1997. Journal of Seismology, 1:181-201. [less ▲]

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See detailAvelumab (MSB0010718C ; anti-PD-L1) as a first-line treatment for patients with advanced NSCLC from the JAVELIN Solid Tumor phase 1b trial : safety, clinical activity, and PD-L1 expression
Verschraegen, C.; Chen, F.L.; Spigel, D.R. et al

in Journal of Clinical Oncology (2016), 34

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See detailPhage therapy against antimicrobial resistance, design of the first clinical study Phagoburn.
Jault, Patrick; Gabard, Jérôme; Leclerc, Thomas et al

in Critical Care (2016), 20(Suppl 2), 109

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See detailInvestigation of sol-gel yttrium doped ZnO thin films: structural and optical properties
Ivanova, T; Harizanova, A; Koutzarova, T et al

in Journal of Physics: Conference Series (2016)

Nanostructured metal oxide films are extensively studied due to their numerous applications such as optoelectronic devices, sensors. In this work, we report the Y–Zn–O nanostructured films prepared by sol ... [more ▼]

Nanostructured metal oxide films are extensively studied due to their numerous applications such as optoelectronic devices, sensors. In this work, we report the Y–Zn–O nanostructured films prepared by sol-gel technology from sols with different concentration of yttrium precursor, followed by post-annealing treatment. The Y doped ZnO thin films have been deposited on Si and quartz substrates by spin coating method, then treated at températures ranging from 300-800°C. XRD analysis reveals modification of the film structure and phases in the doped ZnO films. [less ▲]

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See detailCharacteristics and frequency of large submarine landslides at the western tip of the Gulf of Corinth
Beckers, Arnaud; Hubert, Aurelia ULg; Beck, Christian et al

in Geophysical Research Abstracts (2016), 18

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See detailImpact of Age and Treatment Group in Childhood High Hyperdiploid Low Risk B-Cell Acute Lymphoblastic Leukemia (ALL): Results of the CLG-EORTC 58951 Study
Clement, Laura; Suciu, Stefan; Luquet, Isabelle et al

in Blood (2016)

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See detailAntonymic co-presence: overview of the syntactic patterns model
Steffens, Marie ULg

in Studies van de BKL - Travaux du CBL - Papers of the LSB (2016), 10

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See detailDo Burundians have a more positive perception of older people than immigrants or Belgians?
Marquet, Manon ULg; Missotten, Pierre ULg; Nindaba, Desiderate et al

in International Psychogeriatrics (2016), 27(Supplement 1), 70-172

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See detailEnd-to-end continuous manufacturing
Monbaliu, Jean-Christophe ULg

in ChemistryViews (2016)

We will discuss the development and implementation of continuous-flow multistep strategies for the synthesis of high-value added organic targets. Selected examples include unusual reaction conditions such ... [more ▼]

We will discuss the development and implementation of continuous-flow multistep strategies for the synthesis of high-value added organic targets. Selected examples include unusual reaction conditions such as working with solids in microreactors, high temperature reactions and the handling of highly reactive species. [less ▲]

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See detailFramework for building integrated policies regarding forest risk management: Insights from Wallonia (Belgium)
Riguelle, Simon ULg

in Natural Resources and Bioeconomy Studies (2016), 41

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See detailTrace metals in soft tissue of marine bivalve Noah's ark (Arca noao) from Bizerte lagoon (Northern Tunisia)
Ghribi, Feriel; Richir, Jonathan ULg; Boussafa, Dhouha et al

in Rapports et Procès Verbaux des Réunions - Commission Internationale pour l'Exploration Scientifique de la Mer Mediterranée (2016), 41

This study aimed to monitor the bioaccumulation of 5 trace elements (TEs: Zn, Fe, Cu, Cd, and Pb) in the soft tissue of the Ark shell (Arca noae), seasonally sampled in Bizerte lagoon, northern Tunisia ... [more ▼]

This study aimed to monitor the bioaccumulation of 5 trace elements (TEs: Zn, Fe, Cu, Cd, and Pb) in the soft tissue of the Ark shell (Arca noae), seasonally sampled in Bizerte lagoon, northern Tunisia, in order to assess the nutritional quality of this bivalve and to promote its consumption as marine resource in Tunisia. The levels of all trace metals analyzed in Arca noae are below maximum admissible level which makes this species a healthy and safe food for human consumption. [less ▲]

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