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Coghe, Frédéric; Elkarous, Lamine ULg

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See detailGenetic analysis of pig survival in a crossbred population
Dufrasne, Marie ULg; Misztal, Ignacy; Tsuruta, Shogo et al

in Journal of Animal Science (in press)

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See detailA modeling approach to determine the contribution of plant hydraulic conductivities on the water uptake dynamics in the soil-plant-atmosphere system
Lobet, Guillaume ULg; Pagès, Loïc; Draye, Xavier

in IEEE Plant Growth Modeling and Applications (in press)

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See detailChronos et la clé du temps
Desert, Jean-Benoît ULg; Charon, valérie; Triffaux, Jean-Marc ULg

in Revue des Hôpitaux de Jour Psychiatriques et des Thérapies Institutionnelles 2013, 15 : à paraître. (in press), 15

L’argument de ce XLème Colloque des Hôpitaux de jour psychiatriques nous a plongés dans un abîme de questionnements théoriques et pratiques. Défiés par cette immersion dans les tréfonds du modèle, nous ... [more ▼]

L’argument de ce XLème Colloque des Hôpitaux de jour psychiatriques nous a plongés dans un abîme de questionnements théoriques et pratiques. Défiés par cette immersion dans les tréfonds du modèle, nous avons choisi de nous accrocher aux fondements de notre univers. La mythologie grecque sera donc notre source d’inspiration en mettant un dieu antique à notre disposition. Chronos sera notre guide dans un périple réflexif soumettant nos théories et notre pratique à l’épreuve du temps. Le récit de la conception d’un atelier thérapeutique, l’atelier « Art & Temps », sera notre fil d’Ariane dans notre tentative de symboliser notre pratique thérapeutique quotidienne et ses enjeux. Par la suite, l’exposé d’un cas clinique concrétisera un raisonnement théorique visant à situer notre modèle de prise en charge dans le réseau psychiatrique global. [less ▲]

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See detailDes ambassadeurs entre Liège et Bourgogne: Pour une étude des relations diplomatiques des pouvoirs liégeois avec les ducs Valois
Masson, Christophe ULg

in Publication du Centre Européen d'Etudes Bourguignonnes (in press), LIII(2013),

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See detailVie et praxis : le statt de l'organisme dans la Critique de la Raison dialectique
Caeymaex, Florence ULg

in Bulletin d'Analyse Phénoménologique (in press)

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See detailImaginer l’indicible. De la mise en mouvement des images dans les récits de visions de la Trinité des hagiographes et des mystiques médiévaux (VIIe-XIIe siècles)
Close, Florence ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

Cette communication consistait en une réflexion sur les tentatives d’imagination de la Trinité divine, dogme fondamental du christianisme. Elle portait plus particulièrement sur la manière dont les clercs ... [more ▼]

Cette communication consistait en une réflexion sur les tentatives d’imagination de la Trinité divine, dogme fondamental du christianisme. Elle portait plus particulièrement sur la manière dont les clercs et les moines du haut moyen âge et du moyen âge central ont perçu, le temps d’une expérience mystique extraordinaire, les relations unissant les trois personnes divines entre elles. L'auteur pose la question du rôle et de l’importance des représentations mentales et de la traduction picturale de certains détails et mouvements – énoncés ou non dans les traités théologiques, la tradition scripturaire ou les textes liturgiques – dans le processus de compréhension et d’appréhension de ce mystère. Elle n'hésite pas à confronter des images perçues par les visionnaires aux images de la Trinité produites à la même époque (Trône de grâce, Trinité du psautier, Trinité triandrique, Trinité tricéphale/trifrons, Paternité, Trinité à deux médaillons). [less ▲]

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See detailDétection automatique de réminiscences potentielles de Xénophon chez Arrien
Vanhaegendoren, Koen ULg; Vandersmissen, Marc ULg

in Etudes Classiques (Namur, Belgium) (in press)

Depuis des siècles, les spécialistes et les savants des littératures grecque et latine se sont attachés à repérer les citations et les reprises d’un auteur chez un autre en raison de l’importance de ... [more ▼]

Depuis des siècles, les spécialistes et les savants des littératures grecque et latine se sont attachés à repérer les citations et les reprises d’un auteur chez un autre en raison de l’importance de l’imitatio et de l’aemulatio dans le processus de création littéraire des œuvres anciennes. Arrien de Nicomédie en est un parfait exemple puisqu’il s’inspira abondamment de son modèle admiré, Xénophon. C’est pourquoi, après avoir répertorié le plus grand nombre possible de réutilisations déjà mises au jour entre les deux historiens par les philologues de manière livresque, notre projet a pour but de détecter et de commenter de nouvelles réminiscences potentielles de Xénophon dans l’œuvre d’Arrien grâce à un logiciel développé spécifiquement à l’Université de Liège sur base de fichiers de textes lemmatisés en collaboration avec le LASLA. [less ▲]

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See detailHigh-speed imaging use to predict spray retention on barley leaves
Boukhalfa, Hassina dite Hafida ULg; Massinon, Mathieu ULg; Lebeau, Frédéric ULg

in COMMUNICATIONS IN AGRICULTURAL AND APPLIED BIOLOGICAL SCIENCES (in press)

Laboratory studies were conducted to validate the effectiveness of the use of high-speed imaging method to replace chemical nalysis by fluoremetrie. Measurements were performed with a high-speed camera ... [more ▼]

Laboratory studies were conducted to validate the effectiveness of the use of high-speed imaging method to replace chemical nalysis by fluoremetrie. Measurements were performed with a high-speed camera coupled with a retro-LED lighting. Size and velocity of the drop were extracted by image analysis. Drop impact types were determined by the operator. Drops were produced with a flat-fan nozzle mounted on a movable ramp. Two surfactants (Break-Thru® S240 and Li700 ®) were sprayed on BBCH 12 barley leaves to highlight the effect of the reduction of surface tension. Relative volume proportions were computed within of an energy scale divided into 11 classes based on the Weber number. results are compared to the results of the chemical analysis by spectrofluerometry. [less ▲]

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See detailLes ambiguïtés de l’anthropomorphisme : de la divinité agissante à sa statue dans la céramique grecque
Collard, Hélène ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce ... [more ▼]

L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce, la figuration anthropomorphe des dieux est largement majoritaire. Toutefois, en se tournant vers un support particulier, le vase peint, et un type de représentation particulier, la statue divine, on montrera ici que l’anthropomorphisme a pu amener une certaine ambiguïté. Dans la céramique, les représentations de statues fonctionnent sur plusieurs modes, selon la chronologie. C’est ce que l’on propose d’analyser, en examinant un groupe de vases décorés d’un thème semblable et sur lesquels une divinité est représentée, mais soit sous la forme d’une figure « vivante », soit d’une statue plus ou moins bien caractérisée. Cette étude permettra d’aborder les concepts de « fixité » et de « mouvement » de/dans l’image, mais aussi d’explorer quelques pistes de réflexions sur l’image divine et, plus largement, sur les modes de représentation du divin en Grèce ancienne. [less ▲]

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See detailThe soundtrack of RR Lyrae in Omega Cen at high-frequency
Calamida, A.S.; Randall, S.K.; Monelli, M. et al

in Memorie della Società Astronomica Italiana : Journal of the Italian Astronomical Society (in press)

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See detailDiscriminant BOLD Activation Patterns during Mental Imagery in Parkinson’s Disease
Schrouff, Jessica ULg; Cremers, Julien ULg; D'Ostilio, Kevin ULg et al

in Proceedings of MLINI 2012 (in press)

Using machine learning based models in clinical applications has become current practice and can prove useful to provide information at the subject’s level, such as predicting an (early) diagnosis or ... [more ▼]

Using machine learning based models in clinical applications has become current practice and can prove useful to provide information at the subject’s level, such as predicting an (early) diagnosis or monitoring the evolution of a disease. However, the performance of these models depends on the choice of a biomarker to detect the presence or absence of a disease. Choosing a biomarker is not straightforward, especially in the case of Parkinson’s disease when compared to healthy subjects. In the present work, we investigated the mental imagery of gait as a biomarker of Parkinson’s disease and showed that the signal in the mesencephalic locomotor region during the mental imagery of gait at a comfortable pace can discriminate significantly between idiopathic Parkinson’s disease patients and healthy subjects. Although there is room for improvement, the results of this preliminary study are promising. [less ▲]

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See detailZur Stellung des Deutschen in Belgien
Küpper, Achim ULg

in Rundbrief. Mitteilungsblatt des BGDV (in press), 29

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See detailScalar triplet leptogenesis without right-handed neutrino decoupling
Aristizabal Sierra, Diego ULg

in Nuclear Physics B Proceedings Supplement (in press)

We discuss leptogenesis in the context of type-II seesaw in the case in which in addition to the scalar electroweak triplet decays the lepton asymmetry is also induced by right-handed neutrino decays ... [more ▼]

We discuss leptogenesis in the context of type-II seesaw in the case in which in addition to the scalar electroweak triplet decays the lepton asymmetry is also induced by right-handed neutrino decays (mild hierarchical scenarios). We show that within this setup, depending on the relative sizes of the relevant parameters, one can identify three classes of generic models, each one with its own consequences for leptogenesis. [less ▲]

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See detailDo root-emitted volatile organic compounds attract wireworms?
Barsics, Fanny ULg; Latine, Rémi ULg; Gfeller, Aurélie ULg et al

in Communications in Agricultural and Applied Biological Sciences (in press)

Wireworms are the soil dwelling larvae of click beetles (Coleoptera: Elateridae). Their importance as crop pests increases since the efficient chemical means to control them cannot be considered anymore ... [more ▼]

Wireworms are the soil dwelling larvae of click beetles (Coleoptera: Elateridae). Their importance as crop pests increases since the efficient chemical means to control them cannot be considered anymore. Therefore, many integrated pest management strategies have been investigated in the past few years. Most of them rely on the understanding of the ecology of the click beetles during their whole life cycle. We focus our work on the chemical ecology of wireworms, more precisely on the root-emitted volatile organic compounds (VOCs) that might intervene in the food-searching process of the larvae by helping them to find a suitable host-plant or by acting as key factors in the belowground defence mechanism of the plant. Here, we present our first results of dual-choice orientation tests in olfactometric pipes. Wireworms (Agriotes sordidus Illiger) were submitted individually to a variety of olfactory baits ranging from entire barley roots (Hordeum vulgare L. var. Quench) to isolated VOCs identified as part of the emitting profile. The latter was described thanks to HS-SPME samplings and GC-MS analysis, for roots grown in the exact same conditions as for the olfactometric experimentations with entire roots. Most of the experimentations gave significant results. When confronted to volatiles emitted by entire roots, wireworms significantly orientated towards the bait (χ²-goodness-of-fit test, χ²=8, P-value=0.005). This result allowed us to follow up with the same device and to progressively vary the nature of the baits. Our protocol should be used for other plant-wireworm species combinations. Our results should be taken into account in varietal selection, in crop rotation, or in trapping systems aiming at the reduction of the populations of wireworms. [less ▲]

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See detailL’incendie : feu purificateur ?
Close, Florence ULg

in Bulletin de la Société d'Art et d'Histoire du Diocèse de Liège (in press)

Dans la nuit du 3 au 4 août 1312, la Cité de Liège est mise à feu et à sang. Sept siècles plus tard, la mémoire collective liégeoise compte encore cet évènement au nombre des jalons les plus tragiques de ... [more ▼]

Dans la nuit du 3 au 4 août 1312, la Cité de Liège est mise à feu et à sang. Sept siècles plus tard, la mémoire collective liégeoise compte encore cet évènement au nombre des jalons les plus tragiques de l’histoire de la Principauté. Les conditions dans lesquelles moururent les patriciens demeurent inqualifiables, de même que les moyens auxquels recourut la masse populaire révoltée pour venir à bout de son adversaire. Cet évènement anecdotique au regard de la grande histoire met en lumière la place ambivalente du feu dans la vie et la mentalité des hommes et des femmes du Moyen Âge. Il invite à une profonde réflexion mêlant des considérations juridiques, spirituelles, symboliques et anthropologiques [less ▲]

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See detailMEASUREMENT OF SERUM ALBUMIN BY PROTEIN ELECTROPHORESIS AND BROMOCRESOL GREEN METHODS IN CANINE AND EQUINE PATIENTS
Ramery, Eve ULg; Bureau, Fabrice ULg

in Veterinary Clinical Pathology (in press)

Background: Bromocresol green method (BCG) is routinely used in veterinary laboratories to measure albumin. A good agreement between BCG and electrophoresis (SPE) in healthy domestic animals is reported ... [more ▼]

Background: Bromocresol green method (BCG) is routinely used in veterinary laboratories to measure albumin. A good agreement between BCG and electrophoresis (SPE) in healthy domestic animals is reported. However, in human medicine, at low albumin and high globulin concentrations, BCG also binds to α- and β-globulins fractions. Surprisingly, there is no recent literature evaluating the BCG method in diseased domestic animals. Objective: The purpose of the present study was therefore to compare the serum albumin values obtained by SPE and BCG in canine and equine patients. Methods: Albumin measured by BCG and SPE was compared in the serum from 30 canine and 30 equine patients. Results: Good correlation was found (Spearman´s rho rs = 0.91 in dogs and 0.84 in horses). However, Altman and Bland analysis of results showed a positive bias of BCG with SPE (3.41 g/l in horses and 0.41 g/l in dogs) that increased when only hypoalbuminemic patients were considered (4.17 g/l in horses and 1.31 g/l in dogs). Conclusion: Results confirm that, despite good correlation, BCG method tends to overestimate albumin, especially in hypoalbuminemic patients. This is particularly evident in horses. [less ▲]

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See detailOn the Number of Abelian Bordered Words
Rampersad, Narad; Rigo, Michel ULg; Salimov, Pavel ULg

in Lecture Notes in Computer Science (in press)

In the literature, many bijections between (labeled) Motzkin paths and various other combinatorial objects are studied. We consider abelian (un)bordered words and show the connection with irreducible ... [more ▼]

In the literature, many bijections between (labeled) Motzkin paths and various other combinatorial objects are studied. We consider abelian (un)bordered words and show the connection with irreducible symmetric Motzkin paths and paths in Z not returning to the origin. This study can be extended to abelian unbordered words over an arbitrary alphabet and we derive expressions to compute the number of these words. In particular, over a 3-letter alphabet, the connection with paths in the triangular lattice is made. Finally, we study the lengths of the abelian unbordered factors occurring in the Thue--Morse word. [less ▲]

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See detailLepton flavor violation and seesaw symmetries
Aristizabal Sierra, Diego ULg

in Hyperfine Interactions (in press)

When the standard model is extended with right-handed neutrinos the symmetries of the resulting Lagrangian are enlarged with a new global U(1)R Abelian factor. In the context of minimal seesaw models we ... [more ▼]

When the standard model is extended with right-handed neutrinos the symmetries of the resulting Lagrangian are enlarged with a new global U(1)R Abelian factor. In the context of minimal seesaw models we analyze the implications of a slightly broken U(1)R symmetry on charged lepton flavor violating decays. We find, depending on the R-charge assignments, models where charged lepton flavor violating rates can be within measurable ranges. In particular, we show that in the resulting models due to the structure of the light neutrino mass matrix muon flavor violating decays are entirely determined by neutrino data (up to a normalization factor) and can be sizable in a wide right-handed neutrino mass range. [less ▲]

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See detailGenetic analysis of longitudinal measurements of feed intake in Piétrain sire lines
Dufrasne, Marie ULg; Jaspart, Véronique; Wavreille, José et al

in Journal of Animal Science (in press)

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See detailIs ultra-short cold ischemia the key to ischemic cholangiopathy avoidance in DCD-LT?
DETRY, Olivier ULg; DE ROOVER, Arnaud ULg; Cheham, S et al

in Acta Chirurgica Belgica (2013, May), Supplement 113(3), 6729

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See detailTherapeutic Strategy and Patient Outcome during the First 2 Years of Pediatric Crohn’s Disease
Veereman, G; Mahachie John, Jestinah ULg; De Greef, E et al

in Journal of Pediatric Gastroenterology and Nutrition (2013, May)

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See detailHealth economics in osteoarthritis
Hiligsmann, Mickaël ULg; Cooper, Cyrus; Arden, Nigel et al

in Osteoporosis International (2013, April), 24(Suppl.1), 79-80

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See detailReproducibility of joint space width assessment when external calibration on the radiograph is missing
DEROISY, Rita ULg; Reginster, Jean-Yves ULg; Bruyère, Olivier ULg

in Osteoporosis International (2013, April), 24(Suppl.1), 379

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See detailQuality of life in sarcopenia and frailty
Rizzoli, René; Reginster, Jean-Yves ULg; Arnal, Jean-François et al

in Osteoporosis International (2013, April), 24(Suppl.1), 76-77

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See detailRole of nutraceuticals in the symptomatic and structural management of osteoarthritis
Bruyère, Olivier ULg

in Osteoporosis International (2013, April), 24(Suppl.1), 82-83

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See detailInvestigation of potential new targets for the diagnosis and/or the treatment of osteoarthritis
Lambert, Cécile ULg; Dubuc, J.-E.; Montell, E. et al

in Osteoarthritis and Cartilage (2013, April), 21(Supplement April 2013),

Purpose: Synovial inflammation plays a key role in the pathophysiology process of osteoarthritis (OA). We have previously compared the gene expression pattern of synovial cells isolated from inflammatory ... [more ▼]

Purpose: Synovial inflammation plays a key role in the pathophysiology process of osteoarthritis (OA). We have previously compared the gene expression pattern of synovial cells isolated from inflammatory (I) or normal/reactive (N/R) areas of a synovial membrane harvested from the same OA patient. We identified a large number of mediators belonging to key pathways involved in OA pathogenesis. The aim of this study was to validate different potential new targets for the diagnosis and/or the treatment OA. Methods: Synovial cells (SC) were isolated from synovial specimens obtained from OA patients undergoing knee replacement. The inflammatory status of the synovial membrane was characterized according to macroscopic criteria. The biopsies from N/R and I areas were cultured separately for a period of 7 days. Microarray gene expression profiling between N/R and I areas was performed. The biological relevance of up- and down-regulated genes was analyzed with Ingenuity Pathways Analysis. Western blot and immunohistochemistry confirmed the identified genes most differentially expressed in the key pathways. The production of the triggering receptor expressed on myeloid cells-1 (TREM1), the alarmin S100 calcium binding protein A9 (S100A9), the wingless-type MMTV integration site family, member 5A (Wnt-5A) and the stanniocalcin 1 (STC1) were evaluated by Western blot. S100A9, hyaluronan synthase-1 (HAS1) and STC1 expression and localization were investigated by immunohistochemistry. Results: 896 genes differentially expressed in N/R and I areas were identified. The key pathways were related to inflammation, cartilage metabolism, Wnt signaling and angiogenesis. In the inflammatory gene pattern, TREM1 and S100A9 were strongly upregulated. We validated the production of these proteins in OA synovial biopsies by Western blot. TREM1 and S100A9 were increased in I compared to N/R synovial cells culture. S100A9 was observed in the perivascular area and in sublining cells in I synovial biopsies, but not in N/R biopsies. An increased staining was also observed in the intima lining layer of I when compared to N/R biopsies. The most upregulated anabolism enzyme in I synovial biopsies was HAS1. Using immunohistochemistry, we observed in I areas an increase of the HAS1-positive cells mainly in the intima lining. We also studied the protein production of Wnt-5A, the most upregulated intermediate of Wnt signaling pathway. The protein level was increased in I compared to N/R areas. Finally, in the angiogenesis pathway, one the most u-regulated gene was STC1. A significant increase of STC1 production was observed in I areas compared to N/R areas by Western blot. This result was also supported by the immunohistochemical analysis. In I area, the staining for STC1 was more intense in perivascular and sublining cells. Conclusions: Synovial membrane inflammation is a key target for OA treatments. In this work, we have identified proteins involved in the synovitis pathways like angiogenesis, cells infiltration and matrix remodeling. These proteins could be targeted by drugs and used as companion biomarkers for evaluating their efficacy. Although qualitative, our results could also yield to the identification of markers of the disease. This investigation has to be further pursued. [less ▲]

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See detailEffects of chondroitin sulfate on the gene expression profile in the inflamed synovial membrane
Lambert, Cécile ULg; Dubuc, J-E; Montell, E. et al

in Osteoarthritis and Cartilage (2013, April), 21(Supplement April 2013),

Purpose: The aim of the present work was to identify the differentially expressed genes between the inflammatory (I) and normal/reactive (N/R) synovial areas using a unique ex vivo culture model. In a ... [more ▼]

Purpose: The aim of the present work was to identify the differentially expressed genes between the inflammatory (I) and normal/reactive (N/R) synovial areas using a unique ex vivo culture model. In a second step, we investigated the genetic modulatory effects of chondroitin sulfate (CS) in this model. Methods: Synovial cells (SC) were isolated from OA synovial specimens obtained from 12 patients undergoing knee replacement. The inflammatory status of the synovial membrane was characterized according to macroscopic criteria. At the surgery time, the synovial membrane was dissected and biopsies from N/R and I areas cultured separately for a period of 7 days in the absence or in the presence of highly purified bovine CS (200 µg/ml, Bioibérica S.A., Barcelona, Spain). Total RNA was extracted using the RNeasy Mini Kit. RNA purity and quality were evaluated using the Experion RNA StdSens Analysis kit (Bio-rad Laboratories). Gene expression profiling was performed using Illumina’s multi-sample format Human HT-12 BeadChip (Illumina Inc.). Differential analysis was performed with the BRB array tools software. Class Comparison test between N/R and I conditions, N/R and N/R-CS conditions and I and I-CS conditions was based on paired t-test where N/R and I, N/R and N/R-CS and I and I-CS were paired for each patient. The biological relevance of up- and down-regulated genes was analyses with Ingenuity Pathways Analysis (Ingenuity® Systems). Results: From among 47000 probes, 18253 were filtered out. Probes with a p-value below than 0.005 were chosen and classified as up- or down-regulated ones. By this way, 465 differentially expressed genes between N/R and I areas were identified. Many inflammatory mediators appear differentially expressed. The interferon alpha-inductible protein 6 (IFI6) was the most up-regulated. We also identified the hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), the cathepsin K (CTSK), the chemokine (C-X-C motif) ligand 1 (CXCL1) and the EBV-induced G-protein coupled receptor 2 (EBI2). The differential expression of intermediates involved in angiogenesis pathway was also revealed between N/R and I areas. Among them, R-spondin-3 (RSPO3), the secreted phopshoprotein 1 (SPP1) and aquaporin 9 (AQP9) were up-regulated whereas ADAMTS1 was down-regulated. Finally, in the Wnt signaling, RSPO3 was up-regulated unlike dickkopf homolog 3 (DKK3) which was in turn down-regulated. We next performed a class comparison test between N/R and N/R-CS in one hand and between I and I-CS the other hand. 489 genes were identified as differentially expressed genes between N/R and N/R-CS conditions while 219 genes were identified between I and I-CS conditions. In this latter, our attention was focused on the down-regulated genes. Among them, we identified a number implicated in angiogenesis and cell migration pathways. Thus, the endothelial cell-specific molecule-1 (ESM1), the Transmembrane-4-L-six-family-1 (TM4SF1), the 5’-Ectonucleotidase (NT5E) and the growth arrest-specific gene 6 (GAS6) were down-regulated by CS. Conclusions: Our work demonstrates the differential gene expression profile between paired non inflammatory and normal/reactive areas of synovial membrane as well as the modulatory effects of CS on gene expression in the inflammatory areas, especially regarding genes involved in both angiogenesis and cell migration. [less ▲]

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See detailClinical characteristics of patients responsive to whole body vibration
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Maquet, Didier ULg et al

in Osteoporosis International (2013, April), 24(Suppl.1), 243

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See detailOARSI recommended performance-based tests to assess physical function in people with established hip and knee osteoarthritis
Dobson, F.; Hinman, R.S.; Roos, E.M. et al

in Osteoarthritis and Cartilage (2013, April), 21(Supplement April 2013),

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See detailEffects of chondroitin sulfate on the gene expression profile in IL-1β stimulated synovial fibroblast cells cultures
Lambert, Cécile ULg; Dubuc, Jean-Emile; Montell, E. et al

in Osteoarthritis and Cartilage (2013, April), 21(Supplement April 2013),

Purpose: Chondroitin sulfate (CS) is one the most used molecules in the management of OA. In this study, we performed a microarray analysis and identified a differential expression profile between control ... [more ▼]

Purpose: Chondroitin sulfate (CS) is one the most used molecules in the management of OA. In this study, we performed a microarray analysis and identified a differential expression profile between control and IL-1β stimulated synovial fibroblast cells cultures. In a second step, we investigated the effects of CS on this gene expression profile. Methods: OA synovial specimens were obtained from 12 patients undergoing knee replacement. At the surgery time, the synovial membrane was dissected. Synovial fibroblast cells (SFC) were enzymatically isolated and used after four passages (P4). SFC were pre-treated 1 hour with highly purified bovine CS (200 µg/ml, Bioibérica S.A., Barcelona, Spain) before treatment with IL-1β (1 ng/ml) for 24 hours. Total RNA was extracted using the RNeasy Mini Kit. RNA purity and quality were evaluated using the Experion RNA StdSens Analysis kit (Bio-rad Laboratories). Gene expression profiling was performed using Illumina’s multi-sample format Human HT-12 BeadChip (Illumina Inc.). Differential analysis was performed with the BRB array tools software. Class comparison test between control (Ctl) and interleukin (IL)-1β conditions, Ctl and Ctl/CS and IL-1β and IL-1β/CS conditions was based on paired t-test where Ctl and IL-1β, Ctl and Ctl/CS and IL-1β and IL-1β/CS were paired for each patient. The biological relevance of up- and down-regulated genes was analyses with Ingenuity Pathways Analysis (Ingenuity® Systems). Probes with a p-value below 0.001 were chosen and classified as up- or down-regulated ones. Results: 3308 genes were identified as differentially expressed genes between Ctl and IL-1β conditions. We observed a differential profile of expression of major pathways involved in OA pathogenesis. The key identified pathways were related to inflammation, complement cascade, angiogenesis, cartilage catabolism and anabolism and Wnt signaling. In the inflammatory network, the most upregulated cytokines were IL-8 and IL-6 with a fold change of 156.25 and 58.8 respectively. We also identified several chemokines, enzymes and metallothioneins (MTs). Complement factor B (CFB) and complement component 3 (C3) are two factors upregulated in the inflammatory complement cascade. We also identified some genes implicated in the angiogenesis pathway. The most upregulated was Stanniocalcin 1 (STC1) with a fold change of 9.09. The differential expression of intermediates involved in both cartilage anabolism and catabolism was revealed by the IL-1β stimulation, showing an imbalance in favour of catabolism. MMP-3 was largely upregulated (fold change of 62.5). Wnt 5A and low density lipoprotein receptor-related protein (LRP8) were significantly upregulated while frizzled homolog 2 (FZD2) and dickkopf homolog 3 (DKK3) were downregulated in the Wnt signaling pathway. We next performed a class comparison test between Ctl and Ctl/CS in one hand and IL-1β and IL-1β/CS on the other hand. 660 genes were identified as differentially expressed between Ctl and Ctl/CS conditions while 241 genes were identified between IL-1β and IL-1β/CS. Among them, our attention was focused on two genes upregulated in the presence of CS: lysyl oxidase-like 4 (LOXL4) and claudin 11 (CDLN11), two genes that negatively regulate cell invasion. Conclusions: We here evidenced in synovial fibroblast cells the modulation of gene expression following IL-1β stimulation. We also demonstrated the modulatory effects of CS on gene expression and isolated several CS-modulated genes of interest such as LOXL4 and CDLN11, which could constitute new mechanisms of action of the molecule and contribute to explain the symptomatic efficacy of CS in the treatment of OA. [less ▲]

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See detailValidity of the French hip and knee replacement expectations surveys
NEUPREZ, Audrey ULg; François, Garance ULg; Delcour, JP et al

in Osteoporosis International (2013, April), 24(Suppl.1), 374

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See detailPlanet TOPERS: Planets, Tracing the Transfer, Origin, Preservation, and Evolution of Their Reservoirs
Dehant, V.; Van Hoolst, T.; Breuer, D. et al

in Geophysical Research Abstracts (2013, April), 15

An overview is given of the Planet TOPERS project addressing habitability in our solar system.

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See detailThe intra-articular injection of a new chitosan biomaterial prevents the progression of osteoarthritis in ACLT rabbit model
Oprenyeszk, Frédéric ULg; Chausson, Mickael; Maquet, Véronique et al

in Osteoarthritis and Cartilage (2013, April), 21(Supplement April 2013), 69

Purpose To evaluate the effects of a single intra-articular injection of a new biomaterial consisting in a mix of alginate-chitosan (AC) beads and a viscous thermogelling chitosan-based (H) hydrogel on ... [more ▼]

Purpose To evaluate the effects of a single intra-articular injection of a new biomaterial consisting in a mix of alginate-chitosan (AC) beads and a viscous thermogelling chitosan-based (H) hydrogel on cartilage lesion in osteoarthritis (OA) rabbit model. These effects were compared to those obtained with the intra-articular injection of either chitosan-based (H) hydrogel without the AC bead or saline solution. Methods OA was surgically induced by the transection of the anterior cruciate ligament (ACLT) in HYLA albino rabbits. One week after surgery, animals were randomly divided into 3 groups: group I (n=7): mix of AC beads and H hydrogel; group II (n=7): H hydrogel alone; group III (n=7): saline solution (control). The treatments (900 µl) were injected intra-articularly. X-rays from the right knee were performed before surgery, at the time of injection and at sacrifice. The standard radiographs were acquired in extension and scored by the Kellgren and Lawrence (K&L) scale. After 6 weeks, animals were euthanized and the right joint was dissected. The macroscopic evaluation of cartilage from femoral condyles and tibial plateaus stained with India ink was done. Histological sections stained with Safranine-O/fast green from bearing areas of each compartment were evaluated according to the OARSI histological score. Briefly, the evaluation considered: staining of the cartilage matrix (0-6), cartilage structure (0-11), chondrocyte density (0-4) and cluster formation (0-3), where 0 represented a normal situation and 24 points the maximum severity score. Blood samples were collected the day of injection and prior the sacrifice. Prostaglandin E2 (PGE2) and C-reactive protein (CRP) were measured in serum using immunoassays. Results The X-rays analysis showed a significant decrease (p <0.05) of the K&L score in group I (AC beads and H hydrogel; 1.5 ± 0.2) compared with group II (H hydrogel; 2.2 ± 0.5) and group III (saline solution; 3.0 ± 0.4). The size and the severity of the macroscopic OA cartilage lesion tended to decrease in group I compared to the other groups. The histological global score that refers to all compartments of the knee joint was significantly decreased in group I (11.0 ± 0.7) compared to group II (14.4 ± 0.6, p <0.01) and group III (14.8 ± 0.6, p <0.001). No significant variation of PGE2 and CRP serum levels were observed in each after 6 weeks follow-up whatever the treatment injected. Conclusions This study showed that a biphasic hydrogel composed by AC beads and H hydrogel prevented OA in rabbit with ACL transection. This effect was not observed with the hydrogel alone, suggesting that AC beads play a role in joint protection. The preventive effect was observed in all joint compartments indicating a global protective effect of this new viscosupplementation. [less ▲]

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See detailWhat is the value of biomarkers for drug development in osteoarthritis?
Lotz, Martin; Martel-Pelletier, Johanne; Christiansen, Claus et al

in Osteoporosis International (2013, April), 24(Suppl.1), 77-78

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See detailStrontium ranelate improves osteoarthritis symptoms compared to placebo in patients with knee OA: The SEKOIA study
Bruyère, Olivier ULg; Richette, P; Bellamy, N et al

in Osteoporosis International (2013, April), 24(Suppl.1), 49-51

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See detailChanges in the structure and the symptoms of the osteoarthritis knee and prediction of future knee replacement over an 8-year follow-up period
Bruyère, Olivier ULg; Cooper, Cyrus; Pavelka, Karel et al

in Osteoporosis International (2013, April), 24(Suppl.1), 209

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See detailWhat is the predictive value of MRI for the occurrence of hard clinical endpoints in knee osteoarthritis?
Pelletier, Jean-Pierre; Peterfy, Charles; Brandi, Maria Luisa et al

in Osteoporosis International (2013, April), 24(Suppl.1), 84-85

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See detailQuantitative gait assessment using an accelerometer technology as a predictive tool of falls among nursing home residents: a 6-month prospective study
Bruyère, Olivier ULg; Detalle, Anne-Sophie; Demonceau, Marie ULg et al

in Osteoporosis International (2013, April), 24(Suppl.1), 210

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See detailEvaluation of the impact of a 6-month training by whole body vibration on the risk of falls among nursing home residents
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Demonceau, Marie ULg et al

in Osteoporosis International (2013, April), 24(Suppl.1), 246-247

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See detailNonpharmacological management
Bruyère, Olivier ULg

in Osteoporosis International (2013, April), 24(Suppl.1), 76

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See detailCost-effectiveness of vitamin D and calcium supplementation in the treatment of postmenopausal women
Hiligsmann, Mickaël ULg; Ben Sedrine, Wafa ULg; Rabenda, Véronique ULg et al

in Osteoporosis International (2013, April), 24(Suppl.1), 198

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See detailBelgian multicentre experience with intestinal transplantation
Ceulemans, L; DE ROOVER, Arnaud ULg; DETRY, Olivier ULg et al

in Acta Gastro-Enterologica Belgica (2013, March), 76(1), 07

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See detailAn overview of white dwarf stars
Fontaine, Gilles; Brassard, Pierre; Charpinet, Stéphane et al

in EPJ Web of Conferences (2013, March), 43

We present a brief summary of what is currently known about white dwarf stars, with an emphasis on their evolutionary and internal properties. As is well known, white dwarfs represent the end products of ... [more ▼]

We present a brief summary of what is currently known about white dwarf stars, with an emphasis on their evolutionary and internal properties. As is well known, white dwarfs represent the end products of stellar evolution for the vast majority of stars and, as such, bear the signatures of past events (such as mass loss, mixing phases, loss and redistribution of angular momentum, and thermonuclear burning) that are of essential importance in the evolution of stars in general. In addition, white dwarf stars represent ideal testbeds for our understanding of matter under extreme conditions, and work on their constitutive physics (neutrino production rates, conductive and radiative opacities, interior liquid/solid equations of state, partially ionized and partially degenerate envelope equations of state, diffusion coefficients, line broadening mechanisms) is still being actively pursued. Given a set of constitutive physics, cooling white dwarfs can be used advantageously as cosmochronometers. Moreover, the field has been blessed by the existence of four distinct families of pulsating white dwarfs, each mapping a different evolutionary phase, and this allows the application of the asteroseismological method to probe and test their internal structure and evolutionary state. We set the stage for the reviews that follow on cooling white dwarfs as cosmochronometers and physics laboratories, as well as on the properties of pulsating white dwarfs and the asteroseismological results that can be inferred. [less ▲]

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See detailStockage de bois chablis sous bâche
Castaings, Frédéric; Jourez, Benoît ULg; Riguelle, Simon ULg

in Les infos de RND (2013, March), (1er semestre), 3-5

Le samedi 24 janvier 2009, la tempête Klaus traverse le sud-ouest de la France. Tempête la plus dévastatrice depuis 1999, la forêt des Landes et ses pins maritimes paient un lourd tribut à ce phénomène ... [more ▼]

Le samedi 24 janvier 2009, la tempête Klaus traverse le sud-ouest de la France. Tempête la plus dévastatrice depuis 1999, la forêt des Landes et ses pins maritimes paient un lourd tribut à ce phénomène extrême: 60% de la superficie est touchée, environ 40 millions de m3 de bois sont à terre, quatre fois la récolte annuelle. Il faudra attendre plusieurs mois avant que les aires de stockage par aspersion soient opérationnelles. Trop tard, le pin maritime montre déjà des signes de bleuissement de son bois, il est invendable sur les marchés à forte valeur ajoutée, là où l’esthétisme prime. Écarté des meilleurs débouchés, le lambris et le plancher, le manque à gagner est énorme. Un tel scénario catastrophe, notre région s’y prépare depuis 2005, tirant les enseignements des expériences étrangères et fondant son action sur les spécificités de notre forêt, de notre filière. C’est dans ce cadre que le 28 février dernier, à Eupen, des grumes d’épicéa stockées depuis presque cinq ans ont été extraites des bâches hermétiques qui les protégeaient. Comment le bois est-il ressorti de cette épreuve? Que penser de cette méthode alternative de stockage? Quelle place lui réserver ? Benoit Jourez du Laboratoire de Technologie du Bois du DEMNA (Département de l’Étude du milieu naturel et agricole) nous a apporté son éclairage et nous a conviés à l’ouverture de la poche étanche. Entre supputations et réalité des bois extraits après cinq ans, suspense… [less ▲]

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See detailThe empirical mass distribution of hot B subdwarfs: implications for stellar evolution theory
Van Grootel, Valérie ULg; Fontaine, Gilles; Charpinet, Stéphane et al

in EPJ Web of Conferences (2013, March), 43

Subdwarf B (sdB) stars are hot, compact, and evolved objects that form the very hot end of the horizontal branch, the so-called Extreme Horizontal Branch (EHB). Understanding the formation of sdB stars is ... [more ▼]

Subdwarf B (sdB) stars are hot, compact, and evolved objects that form the very hot end of the horizontal branch, the so-called Extreme Horizontal Branch (EHB). Understanding the formation of sdB stars is one of the remaining challenges of stellar evo- lution theory. Several scenarios have been proposed to account for the existence of such objects, made of He-burning core surrounded by very thin H-rich envelope. They give quite different theoretical mass distributions for the resulting sdB stars. Detailed astero- seismic analyses, including mass estimates, of 15 pulsating hot B subdwarfs have been published since a decade. The masses have also been reliably determined by light curve modeling and spectroscopy for 7 sdB components of eclipsing and/or reflection effect binaries. These empirical mass distributions, although based on small-number statistics, can be compared with the expectations of stellar evolution theory. In particular, the two He white dwarfs merger scenario does not seem to be the dominant channel to form iso- lated sdB stars, while the post-red giant branch scenario is reinforced. This opens new questions on extreme mass loss of red giants to form EHB stars, possibly in connection with the recently discovered close substellar companions and planets orbiting sdB stars. [less ▲]

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See detailAsteroseismology of hot B subdwarf stars
Charpinet, Stéphane; Van Grootel, Valérie ULg; Brassard, Pierre et al

in EPJ Web of Conferences (2013, March), 43

Nonradial pulsations in Extreme Horizontal Branch stars (also known as hot B subdwarfs or sdB stars) offer strong opportunities to study through asteroseismology the structure and internal dynamics of ... [more ▼]

Nonradial pulsations in Extreme Horizontal Branch stars (also known as hot B subdwarfs or sdB stars) offer strong opportunities to study through asteroseismology the structure and internal dynamics of stars in this intermediate stage of stellar evolution. Most sdB stars directly descend from former red giants and are expected to evolve straight into white dwarfs after core helium exhaustion. They thus represent the most direct link between these two stages. Their properties should therefore reflect both the outcome of the core evolution of red giant stars and the initial state for a fraction of the white dwarfs. We review the status of this field after a decade of efforts to exploit both p-mode and g-mode pulsating sdB stars as asteroseismic laboratories. From the discoveries of these two classes of pulsators in 1997 and 2003, respectively, up to the current epoch of data gathering of unprecedented quality from space, a lot of progress has been made in this area and prospects for future achievements look very promising. [less ▲]

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See detailDevelopment of an experimental device allowing plant-plant interaction studies and in situ dynamic trapping of volatile organic compounds emitted by barley (Hordeum distichon L.) roots
Delory, Benjamin ULg; Delaplace, Pierre ULg; Fauconnier, Marie-Laure ULg et al

in Communications in Agricultural and Applied Biological Sciences (2013, February), 78(1), 97-102

In response to wounding or herbivore attack, leaves and roots of higher plants release volatile organic compounds (VOCs). To date, VOCs analysis and plant−plant interaction studies have been mainly ... [more ▼]

In response to wounding or herbivore attack, leaves and roots of higher plants release volatile organic compounds (VOCs). To date, VOCs analysis and plant−plant interaction studies have been mainly performed on aboveground plant tissues, leaving the roles played by root VOCs in plant−plant interaction unexplored. In this context, this project aims at setting up an original experimental device allowing both dynamic trapping of VOCs emitted by mechanically damaged H. distichon roots and the study of the roles played by root VOCs in intra and interspecific plant−plant interactions. The experimental device consists of Barley seedlings cultivated in closed PTFE reactors filled with wet sand. Before being analysed by gas chromatography−mass spectrometry, root VOCs are trapped via a dynamic system on Tenax cartridges using a charcoal-filtered and humidified air. Preliminary results show that 7 day-old wounded Barley roots emit C9 fatty acid derivatives (E-non-2-enal and nona-2,6-dienal) as major compounds, contrasting with aboveground plant tissues that mainly emit C6 alcohols, aldehydes, and their derivative esters. For plant−plant interaction studies, receiver plants are exposed to an airflow enriched with VOCs from root damaged Barley plants of the same age. [less ▲]

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See detailTherapeutic Strategy and Patient Outcome during the First 2 Years of Pediatric Crohn’s Disease
Veereman, G; Mahachie John, Jestinah ULg; De Greef, E et al

in Acta Gastroenterologica Belgica (2013, February)

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See detailLong term measurements of volatile organic compounds exchanges above a maize field at Lonzee (Belgium)
Bachy, Aurélie ULg; Aubinet, Marc ULg; SALERNO, Giovanni ULg et al

in Communications in Agricultural and Applied Biological Sciences (2013, February), 78(1), 127-132

VOC (volatile organic compounds) include a wide set of molecules which are mostly emitted by the plants. Atmospheric scientists are strongly interested in these compounds because of their important role ... [more ▼]

VOC (volatile organic compounds) include a wide set of molecules which are mostly emitted by the plants. Atmospheric scientists are strongly interested in these compounds because of their important role in the atmospheric chemistry and their final impact on air pollution and climate change. Evaluation of current and future VOC emissions is thus necessary and requires a comprehensive understanding of VOC production and exchange dynamics under a wide panel of climatic conditions and ecosystems. Forest and non pastured grasslands have been largely studied for the last decade. However, knowledge about VOC fluxes from croplands remains scarce. Our study focuses on the VOC exchanges between a maize field and the atmosphere. It is incorporated in a wider project that aims to study VOC fluxes from two croplands (maize and winter wheat) and a pastured grassland. VOC fluxes have been measured on a maize field during the whole growing season using a micrometeorological method (eddy covariance). While first results show half-hourly bidirectionnal exchanges among all the preselected compounds, in average methanol stands for the greatest emitted VOC, followed by green leaf volatiles, and acetic acid is the greatest taken up VOC. Small isoprene and monoterpenes fluxes are also observed. A diurnal pattern is found for all those VOC, with greater emission/uptake during the day, suggesting a flux dependence on environmental parameters. These environmental controls will be further investigated [less ▲]

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See detailDevelopment of a test to assess the Banana Bunchy Top Virus transmissibility through direct analysis of its aphid vector Pentalonia nigronervosa
De Clerck, Caroline ULg; Francis, Frédéric ULg; Lepoivre, Philippe ULg et al

in Communications in Agricultural and Applied Biological Sciences (2013, February), 78(1), 49-54

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See detailEstimation of the fascine efficiency in terms of runoff infiltration and sediments deposition
Degré, Aurore ULg; Pineux, Nathalie ULg; Cantreul, Vincent ULg et al

in Geophysical Research Abstracts (2013), 15

Runoff inundations and mudflows are more and more frequent phenomena. In 2011, Belgium had a lot of its municipalities affected by this problematic. Since then, mitigation measures are more and more set ... [more ▼]

Runoff inundations and mudflows are more and more frequent phenomena. In 2011, Belgium had a lot of its municipalities affected by this problematic. Since then, mitigation measures are more and more set up in agricultural watersheds. The fascines are one of these measures which allow to protect the public and private infrastructures and in the same way, which don’t reduce the famers productivity. They consist in branches faggots piled up between two rows of stakes. These linear constructions are mainly put in place across concentrated runoff axis in order to slow down the water and to filter the mud. Only few quantifications of their effectiveness (in terms of flow and concentration water reduction) exist and are however needed to better recommend these types of mitigation measures. Our experiment aims at measuring discharge and mud concentration reduction due to the fascines in a completely defined context. The tests were realised through fascines planted in field border. A watertight surface of 2,45m to 0,80m carries the water to the fascines. Three types of fascines were tested (willow wood fascine, straw fascine, straw compacted fascine), three different water flows were applied (0,5L/s, 3L/s and 6L/s) and three water concentration in dry soil (13g/L, 26g/L, 38g/L) were used. The different factor combinations were tested. The results show that we can expect a reduction of 60% of the flow for the biggest water flows (proportional efficiency with the water flow). The factor interaction study doesn’t allow to see a difference between the type. About the sediment water concentration, the filtration can reach 50%, the fascine with wood faggots showing a better efficiency. Finally, the difference between the fascine type show that straw fascine can support a biggest watershed (25 hectares) than the wood faggot fascine can (5-10 hectares) but during a smaller return period (one year against five years). [less ▲]

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See detailHypovitaminosis D and osteoporosis in burn patients: are the current practices enough ?
ROUSSEAU, Anne-Françoise ULg; LEDOUX, Didier ULg; DAMAS, Pierre ULg et al

in Osteoporosis International (2013), 24(Suppl 1), 377

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See detailStrunian Rugose and Tabulate corals from Northwestern Turkey
Denayer, Julien ULg

in Document de l'Institut Scientifique, Rabat (2013), 26

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See detailSNR dependence of mean kurtosis and how to correct it
Andre, Elodie; Phillips, Christophe; Farrher, Ezequiel et al

in Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society For Magnetic Resonance in Medicine. Scientific Meeting and Exhibition (2013), 21

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See detailVisean corals from the transverse Jebel Begaa to Gara el Itima (eastern Tafilalt, Morocco)
Aretz, Markus; Denayer, Julien ULg

in Document de l'Institut Scientifique, Rabat (2013), 26

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See detailMise en image du spectacle et spectacularisation de l’image à l’âge baroque
Delfosse, Annick ULg; Dekoninck, Ralph; Delbeke, Maarten et al

in Degrés : Revue de Synthèses à Orientation Sémiologique (2013)

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See detailSymmetries in multi-Higgs-doublet models
Ivanov, Igor ULg; Vdovin, Evgeny

in AIP Conference Proceedings (2013)

We report the recent progress in understanding of symmetries which can be implemented in the scalar sector of electroweak symmetry breaking models with several Higgs doublets. In particular we present the ... [more ▼]

We report the recent progress in understanding of symmetries which can be implemented in the scalar sector of electroweak symmetry breaking models with several Higgs doublets. In particular we present the list of finite reparametrization symmetry groups which can appear in the three-Higgs-doublet models. [less ▲]

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See detailSelf-shuffling words
Charlier, Emilie ULg; Kamae, Teturo; Puzynina, Svetlana et al

in Lecture Notes in Computer Science (2013)

In this paper we introduce and study a new property of infinite words which is invariant under the action of a morphism: We say an infinite word x, defined over a finite alphabet A, is self-shuffling if x ... [more ▼]

In this paper we introduce and study a new property of infinite words which is invariant under the action of a morphism: We say an infinite word x, defined over a finite alphabet A, is self-shuffling if x admits factorizations: x=\prod_{i=1}^\infty U_iV_i=\prod_{i=1}^\infty U_i=\prod_{i=1}^\infty V_i with U_i,V_i \in \A^+. In other words, there exists a shuffle of x with itself which reproduces x. The morphic image of any self-shuffling word is again self-shuffling. We prove that many important and well studied words are self-shuffling: This includes the Thue-Morse word and all Sturmian words (except those of the form aC where a is a letter and C is a characteristic Sturmian word). We further establish a number of necessary conditions for a word to be self-shuffling, and show that certain other important words (including the paper-folding word and infinite Lyndon words) are not self-shuffling. In addition to its morphic invariance, which can be used to show that one word is not the morphic image of another, this new notion has other unexpected applications: For instance, as a consequence of our characterization of self-shuffling Sturmian words, we recover a number theoretic result, originally due to Yasutomi, which characterizes pure morphic Sturmian words in the orbit of the characteristic. [less ▲]

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See detailPhysico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration
Nasir, Mehmet Nail ULg; Legrand, Vincent; Gatard, Sylvain et al

in MATEC Web of Conferences (2013), ACCEPTED

Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the ... [more ▼]

Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the pharmaceutical and cosmetic fields. Until now, no detailed analyses of the physico-chemical properties of these compounds have been undertaken. Two symmetrical D-xylose-based bolaforms were chemically synthesized where the two xylose heads are linked via an acetal link to a hydrocarbon chain containing 18 carbon atoms and an unsaturation. The two bolaforms differ only by their anomeric configuration: or The bolaform exhibits interfacial properties at the air-water interface which is not the case for the . FTIR spectroscopy showed that the interactions between the bolaform and POPC, a model phospholipid, involve the carbonyl groups of the phospholipid [less ▲]

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See detailHow adaptation strategies of crops could counteract climate change effects? The case of four catchments in Wallonia, Belgium.
Bauwens, Alexandra ULg; Sohier, Catherine ULg; Degré, Aurore ULg

in Geophysical Research Abstracts (2013), 15

A sharp increase in extreme heat and drought stress is projected in Belgium by the end of the 21st century, with the potential to significantly reduce crops’ yields under current agricultural practices ... [more ▼]

A sharp increase in extreme heat and drought stress is projected in Belgium by the end of the 21st century, with the potential to significantly reduce crops’ yields under current agricultural practices. This contribution uses an agro-hydrological model in order to assess the potential effects of climate evolution on crop development, yield, and water balance for the main agricultural productions in the Meuse catchment. Erosion risk is also evaluated. We show that grasslands and maize yield decrease and yield variability increases under climate change scenarios. The leaf area index study permits to put in emphasis the earlier start of the vegetation due to warmer climate. It appears that all the sensitive stages occur earlier in the season and that crops are negatively affected by summer drought stress. The better understanding of crops development under evolving climate allows us to propose some changes in agricultural practices and to assess their effectiveness. We evaluate different strategies of adaptation in agricultural practices in order to reduce the potential negative effects of climate change on grasslands and maize production. Adaptation strategies proposed are advanced sowing and harvesting date, introduction of a cover crop for maize and advance in the cutting dates for grasslands. In the particular case of the Vesdre catchment, shifting the growth period of maize permits to avoid the water-deficit period and allow increased yield. This shift makes it possible to introduce a cover crop that will drastically reduce winter soil erosion. For grassland, the adjustment of the cutting dates favored the first cut and the earlier start of the vegetation. The second cut is less profitable due to summer drought stress. The vulnerability assessments focused on the main rotation encountered in the cultivated areas and in the difference in the cover type of these crops. [less ▲]

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See detailPrediction of residual stresses by FE simulations on bimetallic work rolls during cooling
Neira Torres, Ingrid ULg; Gilles, Gaëtan ULg; Tchuindjang, Jérôme Tchoufack ULg et al

in Computer Methods in Materials Science (2013), 13(1), 84-91

Bimetallic rolls used in the roughing stands of the Hot Strip Mill require mixed properties as a high wear resistance for the shell material and an enhanced toughness for the core material. The bimetallic ... [more ▼]

Bimetallic rolls used in the roughing stands of the Hot Strip Mill require mixed properties as a high wear resistance for the shell material and an enhanced toughness for the core material. The bimetallic roll studied in this paper is obtained from a vertical spin casting process followed by cooling and subsequent heat treatments. Failure of the compound roll sometimes occurs during the cooling stage of the casting route or later during the thermal treatments. It requires to deeply investigate the thermo mechanical metallurgical interactions generated during cooling and heat treatment in order to find the origin of cracks. For this purpose, a thermo metallurgic mechanical finite element model is used. However these numerical simulations require a high amount of mechanical, thermal and metallurgical parameters. In order to determinate these parameters, a study of available data for estimation of mechanical parameters was performed. Thermo physical parameters were obtained by DTA and DSC methods. Metallurgical characterization by inverse numerical method based on available CCT diagrams was performed to determine the TTT diagrams. First cooling numerical simulations are presented, allowing a rough estimate of residual stresses values and the identification of key parameters for predicting accurate residual stresses by sensitivity analysis. [less ▲]

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See detailProbing the phase of the elastic $pp$ scattering amplitude with vortex proton beams
Ivanov, Igor ULg

in AIP Conference Proceedings (2013)

We show that colliding vortex proton beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the scattering amplitude changes with the scattering angle. In ... [more ▼]

We show that colliding vortex proton beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the scattering amplitude changes with the scattering angle. In elastic $pp$ scattering, this will open a novel way to measure the parameter $\rho(t)$ and probe the real part of the Pomeron. [less ▲]

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See detailSpatial distribution of erosion and deposition on an agricultural watershed
Pineux, Nathalie ULg; Colinet, Gilles ULg; Degré, Aurore ULg

in Geophysical Research Abstracts (2013), 15

To better understand the agricultural landscapes evolution becomes an essential preoccupation and, for this, it is needed to take into account the sediments deposition, in a distributed way. As it is not ... [more ▼]

To better understand the agricultural landscapes evolution becomes an essential preoccupation and, for this, it is needed to take into account the sediments deposition, in a distributed way. As it is not possible in practice to study all terrestrial surfaces in detail by instrumenting sectors to obtain data, models of prediction are valuable tools to control the current problems, to predict the future tendencies and to provide a scientific base to the political decisions. In our case, a landscape evolution model is needed, which aims at representing both erosion and sedimentation and dynamically adjusts the landscape to erosion and deposition by modifying the initial digital elevation model. The Landsoil model (Landscape design for Soil conservation under soil use and climate change), among others, could fulfil this objective. It has the advantage to take the soil variability into account. This model, designed for the analysis of agricultural landscape, is suitable for simulations from parcel to catchment scale, is spatially distributed and event-based. Observed quantitative data are essential (notably to calibrate the model) but still limited. Particularly, we lack observations spatially distributed on the watershed. For this purpose, we choose a watershed in Belgium (Wallonia) which is a 124 ha agricultural zone in the loamy region. Its slopes range from 0% to 9%. To test the predictions of the model, comparisons will be done with: - sediment measurements which are done with water samplings in four points on the site to compare the net erosion results; - sediment selective measurements (depth variation observed along graduated bares placed on site) to compare the erosion and deposition results; - very accurate DSM’s (6,76 cm pixel resolution X-Y) obtained by the drone (Gatewing X100) each winter. Besides planning what the landscape evolution should be, a revision of the soil map (drew in 1958) is organized to compare with the past situation and establish how the landscape moved in 50 years. The first results of the sediment measurements and of the pictures of the drone will be showed in the presentation. [less ▲]

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See detailPreliminary data on plicathyridines (Brachiopoda) from the Frasnian of southern Belgium and the Middle East (Afghanistan, Iran)
Mottequin, Bernard ULg; Marion, Jean-Marc ULg; Brice, Denise

in Documents scientifiques de l'Institut de Rabat (2013), 26

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See detailProcessing of Ti alloys by additive manufacturing: a comparison of the microstructures obtained by laser cladding, selective laser melting and electron beam melting
Reginster, Sylvie ULg; Mertens, Anne ULg; Paydas, Hakan ULg et al

in Materials Science Forum (2013)

Additive manufacturing processes such as laser cladding (LC) or selective laser melting (SLM) appear very promising in view of an economic near-net-shape production – and also, in the case of LC, the ... [more ▼]

Additive manufacturing processes such as laser cladding (LC) or selective laser melting (SLM) appear very promising in view of an economic near-net-shape production – and also, in the case of LC, the restoration - of complex and (almost) fully dense parts from Ti alloys. Both techniques involve the melting of a metallic powder with a laser. In the SLM process, the metallic powder is deposited layer by layer in a powder bed and then molten locally according to the desired shape, whereas in LC, the metallic powder is directly projected onto a substrate through a nozzle coaxial with the laser beam. The present research aims at comparing Ti-6Al-4V samples processed by these two techniques with reference samples produced by electron beam melting (EBM), another well established additive manufacturing process (patented by Arcam AB Company) in which a powder bed is molten locally by means of an electron beam. In all three processes, the melt pool undergoes an ultrafast cooling and solidifies very rapidly once the beam has left the area, thus giving rise to strongly out-of-equilibrium microstructures. Yet, each one of these processes also has its own specificities e.g. in terms of scanning strategy and of working atmosphere (low vacuum vs. protective Ar flow). In the present work, the microstructures obtained by these three processes have been compared in details, with a particular attention for characteristics such as porosity, grain size, and the various phases present. Since epitaxial growth of the newly deposited layer on the material previously solidified has been shown [1, 2] to exert a strong influence on the microstructure and on the resulting mechanical properties, great care has been taken to study the microstructural anisotropy associated with each one of the three processes. [less ▲]

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See detailIdentifying early Earth microfossils in unsilicified sediments
Javaux, Emmanuelle ULg; Asael, Dan; Bekker, Andrey et al

in Geophysical Research Abstracts (2013), 15

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See detailHydrological and geopedological dynamics of a forested slope
Deraedt, Deborah ULg; Degré, Aurore ULg; Colinet, Gilles ULg

in Geophysical Research Abstracts (2013), 15

Though forested watersheds are really particular in terms of hydrodynamics, most of the hydrological models oversimplify the phenomena involved. More investigations are unavoidable to improve the ... [more ▼]

Though forested watersheds are really particular in terms of hydrodynamics, most of the hydrological models oversimplify the phenomena involved. More investigations are unavoidable to improve the knowledge and the modelling of this environment. Here is the aim of this study. The studied slope is located on the Houille watershed in the West of the Belgian Ardenne (50 1’47”N, 4 53’22”E) on a silty rocky soil. The site is situated under a Douglas fir (Pseudotsuga menziesii (MIRB.) FRANCO) and spruce stand cover (Picea abies (L.) Karst). It is about 160 meters long with a North-West facing slope between 7 and 55%. The goal of the study is : - to characterise the hydrological and pedogeological dynamics along a forested slope, - to compare these dynamics with the tree growth. For the geopedological part of the study, eight pits were dug to describe the soil and take some soil samples used for granulometric, chemical, etc. analysis. We have used geophysical methods (Electrical Resistivity Tomography and Ground Penetrating Radar) to estimate the soil depth. As for the hydrological part of this study, moisture sensors (capacitive and TDR) have been installed in the pits along the slope. A dye tracing test has been performed to underline the preferential flow and the importance of the subsurface flow. Several trees have been equipped with dendrometers and some measures of the LAI and the height of the trees are planned. [less ▲]

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See detailInitiation of methane turbulent flux measurements over a grazed grassland in Belgium
Dumortier, Pierre ULg; Aubinet, Marc ULg; Chopin, Henri ULg et al

in Geophysical Research Abstracts (2013), 15

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See detailFirst retrievals of HCFC-142b from ground-based high resolution FTIR solar observations: application to high altitude Jungfraujoch spectra
Mahieu, Emmanuel ULg; O'Doherty, Simon; Reimann, Stefan et al

in Geophysical Research Abstracts (2013), 15

Hydrofluorocarbons (HCFCs) are the first substitutes to the long-lived ozone depleting halocarbons, in particular the chlorofluorocarbons (CFCs). Given the complete ban of the CFCs by the Montreal ... [more ▼]

Hydrofluorocarbons (HCFCs) are the first substitutes to the long-lived ozone depleting halocarbons, in particular the chlorofluorocarbons (CFCs). Given the complete ban of the CFCs by the Montreal Protocol, its Amendments and Adjustments, HCFCs are on the rise, with current rates of increase substantially larger than at the beginning of the 21st century. HCFC-142b (CH3CClF2) is presently the second most abundant HCFC, after HCFC-22 (CHClF2). It is used in a wide range of applications, including as a blowing foam agent, in refrigeration and air-conditioning. Its concentration will soon reach 25 ppt in the northern hemisphere, with mixing ratios increasing at about 1.1 ppt/yr [Montzka et al., 2011]. The HCFC-142b lifetime is estimated at 18 years. With a global warming potential of 2310 on a 100-yr horizon, this species is also a potent greenhouse gas [Forster et al., 2007]. First space-based retrievals of HCFC-142b have been reported by Dufour et al. [2005]. 17 occultations recorded in 2004 by the Canadian ACE-FTS instrument (Atmospheric Chemistry Experiment – Fourier Transform Spectrometer, onboard SCISAT-1) were analyzed, using two microwindows (1132.5–1135.5 and 1191.5–1195.5 cm-1). In 2009, Rinsland et al. determined the HCFC-142b trend near the tropopause, from the analysis of ACE-FTS observations recorded over the 2004–2008 time period. The spectral region used in this study extended from 903 to 905.5 cm-1. In this contribution, we will present the first HCFC-142b measurements from ground-based high-resolution Fourier Transform Infrared (FTIR) solar spectra. We use observations recorded at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl), with a Bruker 120HR instrument, in the framework of the Network for the Detection of Atmospheric Composition Change (NDACC, visit http://www.ndacc.org). The retrieval of HCFC-142b is very challenging, with simulations indicating only weak absorptions, lower than 1% for low sun spectra and current concentrations. Among the four microwindows tested, the region extending from 900 to 906 cm-1 proved to be the most appropriate, with limited interferences, in particular from water vapor. A total column time series spanning the 2004-2012 time period will be presented, analyzed and critically discussed. After conversion of our total columns to concentrations, we will compare our results with in situ measurements performed in the northern hemisphere by the AGAGE network. [less ▲]

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See detailThe neural correlates of recollection and familiarity during aging
Angel, Lucie; Bastin, Christine ULg; Genon, Sarah ULg et al

in Journal of Psychophysiology (2013), 27(Suppl 1), 48

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See detailInfluence of lignin in Reticulitermes santonensis: symbiotic interations investigated through proteomics
Bauwens, Julien ULg; Tarayre, Cédric ULg; Brasseur, Catherine ULg et al

in Symbiosis (2013)

The gut of lower termites is populated by numerous microbial species belonging to prokaryotes, fungi, yeasts and protists. These micro-organisms are organized in a complex symbiotic system, interacting ... [more ▼]

The gut of lower termites is populated by numerous microbial species belonging to prokaryotes, fungi, yeasts and protists. These micro-organisms are organized in a complex symbiotic system, interacting together and with the insect host. Their likely ability to degrade ligno-cellulosic compounds could lead to improvements in second generation biofuels production. Lignin elimination represents a critical point as this polymer significantly interferes with industrial process of cellulose. Although host produces its own lignin-degrading enzymes, some symbionts may participate in digestion of lignin and its degradation products in termite gut. Here, we compared gut proteomes from R. santonensis after rearing on artificial diets composed of cellulose with and without lignin. The effect of lignin in artificial diets on different parts of the digestive tract was compared through liquid chromatography associated with tandem mass spectrometry (LC-MS/MS) experiments. Enzymatic assays were performed to characterize activities present in R. santonensis digestive tract after feeding on artificial diets. Microscopic observations of microbial communities provided some information on population balances after feeding experiment. [less ▲]

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See detailEvaluation d'un protocole de prise en charge nutritionnelle interdisciplinaire chez des patients brulés
MALHERBE, Christian ULg; VERBRUGGE, Anne-Marie ULg; MAGNETTE, André ULg et al

in Nutrition Clinique et Metabolisme (2012, December), 26-Supp1

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See detailUse of medium without reducing agent for in vitro fermentation studies by bacteria isolated from pig intestine
POELAERT, Christine ULg; Boudry, Christelle ULg; Portetelle, Daniel ULg et al

in Journal of Animal Science (2012, December), 90(Supplement 4), 387-389

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See detail(Pré)textes : perspective didactique sur le dépeçage des textes littéraires à des fins d'exemplification
Van Beveren, Julien ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (2012, December), 4

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See detailPotentiel de dispersion du sanglier et historique de la colonisation de la plaine agricole
Morelle, Kevin ULg; Prévot, Céline

in Forêt Wallonne (2012, December), 121

Les populations de sangliers augmentent en nombre et étendent leur aire de répartition un peu partout en Europe. En Wallonie, la population de sangliers a quadruplé en 30 ans. Plusieurs études se sont ... [more ▼]

Les populations de sangliers augmentent en nombre et étendent leur aire de répartition un peu partout en Europe. En Wallonie, la population de sangliers a quadruplé en 30 ans. Plusieurs études se sont penchées sur le sujet et les raisons de cette augmentation concernent souvent l’influence du climat. Grâce aux différents suivis réalisés par le DEMNA, les déplacements au sein des populations de sangliers sont mieux compris. L’article se penche d’abord sur le potentiel de dispersion du sanglier en se basant sur les données de bagage de marcassins. Deux variables sont analysées : la distance parcourue dans le cadre de la dispersion natale (mouvement à sens unique à partir du site de naissance d’un individu jusqu’à son site de première reproduction) et le taux de cette dispersion natale. Quelques résultats provenant d’une étude génétique sont également présentés. Le génotypage de 1153 sangliers répartis sur l’ensemble de la Wallonie a mis en évidence quatre sous-populations génétiquement homogènes. Parallèlement à l’augmentation de la taille de ses populations, le sanglier a vu son aire de distribution s’accroître en Wallonie. Un suivi par enquête a été réalisé auprès des conseils cynégétiques et des agents du DNF pour mieux comprendre l’expansion géographique observée. Une première phase de l’enquête visait à retracer l’expansion géographique du sanglier en Wallonie. La seconde phase consistait à réaliser un état des lieux sur la situation actuelle de la distribution du sanglier en périphérie du sillon Sambre-et-Meuse. [less ▲]

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See detailNon-thermal radiation from a runaway early-type star
del Valle, M.; Romero, G.E.; De Becker, Michaël ULg

in AIP Conference Proceedings (2012, December), 1505

HD 195592 is an O-type supergiant star, known as a well-established runaway. Recently, a Fermi γ-ray source (2FGL J2030.7+4417) with a position compatible with that of HD 195592 has been reported. Our ... [more ▼]

HD 195592 is an O-type supergiant star, known as a well-established runaway. Recently, a Fermi γ-ray source (2FGL J2030.7+4417) with a position compatible with that of HD 195592 has been reported. Our goal is to explore a scenario where HD 195592 is the counterpart of the Fermi γ-ray source. The high-energy emission would be inverse Compton radiation produced in the bowshock of the runaway star. We calculate relativistic particle energy losses and the resulting radiation from the bowshock of HD 195592 and show that the latter is compatible with the detected γ-ray emission. We conclude that the Fermi source 2FGL J2030.7+4417 might be produced, under some energetic assumptions, by inverse Compton up-scattering of infrared photons from locally heated dust. HD 195592 might therefore be the very first object detected belonging to the category of γ-ray emitting runaway massive stars, whose existence has been recently predicted. [less ▲]

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See detailVocal Impact of a Prolonged Reading Task in Dysphonic versus Normophonic Female Teachers
Remacle, Angélique ULg; Morsomme, Dominique ULg; Berrué, Elise et al

in Journal of Voice (2012, November), 26(6), 8201-82013

OBJECTIVES: This study evaluates the impact on voice of a 2-hour reading task between 70-75 dB(A) in 16 normophonic and 16 dysphonic female teachers with vocal nodules. METHODS: Objective measurements ... [more ▼]

OBJECTIVES: This study evaluates the impact on voice of a 2-hour reading task between 70-75 dB(A) in 16 normophonic and 16 dysphonic female teachers with vocal nodules. METHODS: Objective measurements (acoustic analysis, voice range measurements, aerodynamic measurements) and subjective self-ratings were collected before the task and every 30 minutes during the reading to determine the voice evolution in both groups. RESULTS: Fundamental frequency, lowest frequency, highest frequency (F-High), highest intensity and intensity range increase through the reading, whereas Shimmer decreases. Maximum phonation time decreases after 30 minutes. Estimated subglottal pressure (ESP) and sound pressure level increase during the first hour. Afterwards, ESP decreases. Self-ratings worsen through time. When comparing the normophonic and the dysphonic teachers, self-ratings reveal more complaints in the dysphonic group. Few differences in objective measurements are found between both groups: normophonic teachers show lower ESP, higher F-High and greater frequency range. CONCLUSIONS: Frequency modifications from acoustic analysis and voice range measurements suggest an increased laryngeal tension during vocal load, while subjects perceive a worsening of voice. Aerodynamic parameters depict first a deterioration of voice efficiency and then an adaptation to the prolonged reading. The comparison between both groups shows a discrepancy between objective measurements and self-ratings, suggesting that both approaches are necessary to have a complete view of vocal load effects. Surprisingly, both groups behave similarly through vocal load, without more or quicker deterioration of voice in the dysphonic group. [less ▲]

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See detailEvaluation de l’impact de la filiere de production porcine sur les caractéristiques des jambons de l’IGP (Indication Géographique Protégée) Jambon d’Ardenne
Dzaomuho-Lenieregue, Phidias ULg; Eloundou Mballa, Pierre; Sindic, Marianne ULg et al

in Viandes et Produits Carnés (2012, November), Hors-Série

The aim of this study is to evaluate the influence of pork production sector on technological behavior of raw material, properties of the ham final product and consumer preferences. An experimental ... [more ▼]

The aim of this study is to evaluate the influence of pork production sector on technological behavior of raw material, properties of the ham final product and consumer preferences. An experimental manufacturing assay of Ardenne Ham has been conducted for this purpose. Results show few incidence of pork production conditions on technological properties and chemical or sensory characteristics of hams. The preference tests, carried out with a sensory panel using several criteria, showed that consumers were able to distinguish two groups of hams, according to their fat content. They have a preference for lower-fat ham from one of the studied sectors. Method of multicriteria decision shows no overall preference for one of the submitted ham. [less ▲]

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See detailPrognostic Value of Serologic and Histologic Markers on Clinical Relapse in Ulcerative Colitis Patients With Mucosal Healing
Bessissow, Talat; Lemmens, Bart; Ferrante, Marc et al

in American Journal of Gastroenterology (2012, November), 11(107), 1684-92

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See detailCouplage des modèles numériques SWAT et FeFlow pour l'étude des flux de nitrate à l'échelle d'un bassin versant agricole posé sur un aquifère sableux. Calibrage, validation et test de scénarios pour l'évaluation de pratiques agricoles plus durables en terme de gestion de l'azote
Vandenberghe, Christophe ULg; Deneufbourg, Mathieu ULg; Gaule, David et al

in Bulletin du groupe francophone Humidimétrie et Transferts en milieux poreux (2012, November), 58

Quatre prises d’eau exploitées à Arquennes (Belgique) sont contaminées par le nitrate. Leurs bassins d’alimentation sont situés en zone agricole caractérisée par un sol limoneux sur un aquifère sableux ... [more ▼]

Quatre prises d’eau exploitées à Arquennes (Belgique) sont contaminées par le nitrate. Leurs bassins d’alimentation sont situés en zone agricole caractérisée par un sol limoneux sur un aquifère sableux. Depuis 2004, ces bassins servent de site pilote dans le cadre de l’évaluation du Programme de Gestion Durable de l’Azote (PGDA), transposition de la Directive « Nitrates » en droit wallon. Les modèles numériques SWAT et FEFLOW ont permis de simuler les flux d’eau et de nitrate depuis la surface jusqu’aux galeries. Après calibrage et validation des modèles (sur la base d’une caractérisation du sol et du sous-sol et de traçages en milieux saturé et non saturé), plusieurs scénarios de pratiques agricoles ont été simulés afin de prédire l’évolution qualitative des eaux. L’expérience d’Arquennes a démontré que le recours au couplage SWAT / FEFLOW permet de proposer des solutions environnementales réalistes pour atteindre les objectifs fixés par la DCE. [less ▲]

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See detailHighly excited states of baryond in large Nc QCD
Matagne, Nicolas; Stancu, Floarea ULg

in Bled Workshops in Physics (2012, November), 13(1), 47-53

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See detailWhat is the potential increase of the heart graft pool by cardiac donation after circulatory death?
NOTERDAEME, Timothée; NELLESSEN, Eric ULg; HANS, Marie-France ULg et al

in Transplantation (2012, November), 94

Background: Heart transplantation remains to date the only definite treatment option for end-stage heart diseases. Currently only heart procured from brain death (DBD) donors are used. Combined with an ... [more ▼]

Background: Heart transplantation remains to date the only definite treatment option for end-stage heart diseases. Currently only heart procured from brain death (DBD) donors are used. Combined with an increasing demand, the constant heart graft shortage leads to an increase of deaths on cardiac transplantation waiting lists. The use of hearts procured after donation after circulatory death (DCD) could help to partly decrease the heart graft shortage. The aim of this study was to evaluate the potential increase of heart graft pool by development of DCD heart transplantation. Methods: The authors retrospectively reviewed their local donor database for the period 2006-2011, and screened the complete controlled DCD donor population for potential heart donors, using the same criteria as for DBD heart transplantation. The acceptable warm ischemic time (WIT) was limited to 30min from life support withdrawal to aortic cannulation. Results: During the analyzed timespan, 177 DBD and 70 DCD were effectively performed. From the 177 DBD, a total of 70 (39.5%) hearts were procured and transplanted locally or in another center. Out of the 70 DCD, 8 (11%) donors fulfilled the criteria for heart graft procurement and had a WIT of less than 30 minutes. During the same period, 82 patients were newly listed for heart transplantation, of which 53 were transplanted, 20 died or were unlisted, and 9 were still awaiting transplantation. Conclusions: Based on our database and a WIT of less than 30min, it could be estimated that 11% of the DCD might be heart graft donors, representing a 11% increase in heart graft procurement, as well as potential reduction of the deaths on the waiting list by 40%. [less ▲]

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See detailDoes processing speed protect from age-related decline in cognitive control?
Manard, Marine ULg; Carabin, Delphine; Collette, Fabienne ULg

in Frontiers in Human Neuroscience (2012, October 27)

Age-related difficulties have been reported on proactive control whereas reactive control seems to remain intact (Braver, Gray, & Burgess, 2007; Braver, 2012). This study investigated the potential ... [more ▼]

Age-related difficulties have been reported on proactive control whereas reactive control seems to remain intact (Braver, Gray, & Burgess, 2007; Braver, 2012). This study investigated the potential influence of speed of processing abilities on the age-related decline in proactive control. We used a working memory recognition paradigm involving proactive or reactive cognitive control by manipulating the interference level across items. 80 young adults (18-29 years old) and 80 healthy older adults (60-89 years old) were included. The main results revealed significant effects of age on sensitivity to interference. As expected, reactive control performance remained intact with aging (similar interference effect in the two groups). In contrast, we observed a larger interference effect in the proactive condition in aging. Finally, when the groups are matched according to their processing speed (assessed by the Code task of the WAIS III, with both younger and older adults having a score comprised between 60 and 93), the effect of age on sensitivity to interference disappeared. In other words, when younger and older adults had similar speed of processing abilities, no age-related proactive control decline was observed. In conclusion, beyond the fact that this study confirms the selective age-related decline in proactive control, it also indicates that speed of processing, a measure considered as reflecting the integrity of cognitive functioning during aging (Salthouse, 1996), influences the efficiency of proactive control in that population. [less ▲]

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See detailDetermination of Romanian alfalfa crude protein and crude fiber contents as well as in vitro organic matter digestibility by NIR spectrometry
Dale, Laura ULg; Thewis, André ULg; Rotar, Ioan et al

in Scientific Papers. Series D, Animal Science (2012, October 04)

Alfalfa (Medicago sativa L.) is a high quality forage which has been used worldwide. The superiority of alfalfa lies in its high yield, high protein content and high digestibility. The aim of this study ... [more ▼]

Alfalfa (Medicago sativa L.) is a high quality forage which has been used worldwide. The superiority of alfalfa lies in its high yield, high protein content and high digestibility. The aim of this study was to develop a simple, fast and non-destructive method, named Near Infrared Spectroscopy (NIRS) to determinate alfalfa quality. To realize this study, alfalfa samples were obtained from Mănăştur Experimental Station – Farm Cojocna in 2008–2009, in one experiment carried out using randomization blocks design with two experimental factors (mineral fertilization and period of harvest). Alfalfa quality was first determinated on 48 samples by classical analyses: crude protein CP (AOAC, 1990), crude fiber CF (Fiber Cap, FOSS, DK) and in vitro organic matter digestibility OMDrt (DeBoever, 1986). Then the samples were scanned by NIRS. Calibration models were performed by PerkinElmer Spectrum Quant + 4.21 program (USA) on the 48 samples determinated by classical analysis. The results showed fully confirmed by acceptable coefficients of determination and standard error of cross-validation (R2=0.96 for CP, 0.94 for CF, 0.98 for OMDrt and SECV=0.77 for CP, 1.35 for CF, 1.13 for OMDrt). Successful results for prediction of other 176 alfalfa samples were then obtained using these calibration models: SEP=0.869 for CP, 1.058 for CF, 1.058 for OMDrt). The highest CP and OMDrt values of alfalfa were obtained in bud stage (22.0% and 66.0% respectively). While for CF, the highest content was registered in the seed formation stage (46.0%). The NIRS technique offers us the possibility to determinate rapidly and easily Romanian alfalfa important parameters, but the system could also be used for the determination of other constituents. [less ▲]

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See detailPulsational Mode Identification Based on Chromatic Amplitude Behaviour: Recent Results for Rapidly Oscillating Subdwarf B Stars
Randall, S.K.; Fontaine, G.; Brassard, P. et al

in Leaflet - Astronomical Society of the Pacific (2012, October), 462

We present recent results from mode identification based on the amplitude-wavelength behaviour for three rapidly pulsating subdwarf B stars: HS 2201+2610, EC 11583–2708 and EC 20338–1925.

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See detailCumulative Time in Band (cTIB): Glycemic Level, Variability and Patient Outcome All in 1
Penning, Sophie ULg; Signal, Matthew; Preiser, Jean-Charles et al

in Intensive Care Medicine (2012, October), 38 (Suppl 1)

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See detailAssociation between chondrocytes hypertrophy and angiogenesis of cartilage in osteoarthritis
Pesesse, Laurence ULg; Sanchez, Christelle ULg; Delcour, Jean-Pierre et al

in Arthritis and Rheumatism (2012, October), 64(10 (Suppl)), 760

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See detailAccompagnement des aidants des patients Alzheimer comme approche non-pharmacologique essentielle!
Adam, Stéphane ULg; Bottard, Aude ULg; Crespin, Maurane ULg et al

in Revue Francophone de Gériatrie et de Gérontologie (2012, October), XIX(188), 326-327

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See detailArbitrary Lagrangian Eulerian Modelling of Tension Levelling
Boman, Romain ULg; Parrico, Anthony; Legrand, Nicolas et al

in Matériaux et Techniques (2012, October), 100(Hors série 2012), 40-42

This paper presents a two-dimensional model of tension levelling using the Arbitrary Lagrangian Eulerian (ALE) approach. During the simulation, the ALE mesh remains globally fixed along the rolling ... [more ▼]

This paper presents a two-dimensional model of tension levelling using the Arbitrary Lagrangian Eulerian (ALE) approach. During the simulation, the ALE mesh remains globally fixed along the rolling direction. Therefore, the required number of finite elements is much smaller than in the Lagrangian case and smaller CPU times are obtained for the same accuracy on the results. The ALE model is first validated against a classical equivalent Lagrangian model. Then, both sets of numerical results are compared to experimental measurements from the pilot mill of ArcelorMittal Maizières R&D. [less ▲]

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See detailChemometric tools for NIRS and NIR hyperspectral imaging
Dale, Laura ULg; Thewis, André ULg; Rotar, Ioan et al

in Bulletin of USAVM Cluj Napoca, Agriculture (2012, September 27), 69(1), 70-76

Nowadays in agriculture, new analytical tools based on spectroscopic technologies are developed. Near Infrared Spectroscopy (NIRS) is a well known technology in the agricultural sector allowing the ... [more ▼]

Nowadays in agriculture, new analytical tools based on spectroscopic technologies are developed. Near Infrared Spectroscopy (NIRS) is a well known technology in the agricultural sector allowing the acquisition of chemical information from the samples with a large number of advantages, such as: easy to use tool, fast and simultaneous analysis of several components, non-polluting, non-invasive and non destructive technology, and possibility of online or field implementation. Recently, NIRS system was combined with imaging technologies creating the Near Infrared Hyperspectral Imaging system (NIR-HSI). This technology provides simultaneously spectral and spatial information from an object. The main differences between NIR-HSI and NIRS is that many spectra can be recorded simultaneously from a large area of an object with the former while with NIRS only one spectrum was recorded for analysis on a small area. In this work, both technologies are presented with special focus on the main spectrum and images analysis methods. Several qualitative and quantitative applications of NIRS and NIR-HSI in agricultural products are listed. Developments of NIRS and NIR-HSI will enhance progress in the field of agriculture by providing high quality and safe agricultural products, better plant and grain selection techniques or compound feed industry’s productivity among others. [less ▲]

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