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See detailÉVOLUTION DE LA TENEUR EN EAU LE LONG D’UNE TOPOSEQUENCE FORESTIERE ARGILO-LIMONEUSE
Deraedt, Deborah ULiege; Colinet, Gilles ULiege; Degré, Aurore ULiege

in Milieux Poreux et Transferts Hydriques (in press)

For the hydrological modeling of forested watersheds, the understanding of the forest hydrodynamic is essential. This study focusses on the hydrology of a Belgian forested plot with high stoniness and ... [more ▼]

For the hydrological modeling of forested watersheds, the understanding of the forest hydrodynamic is essential. This study focusses on the hydrology of a Belgian forested plot with high stoniness and steep slope. The soil water content is monitored at several positions on the toposequence and at different depth. During rain events, peak in soil water content are observed in different depth depending on the position along the toposequence. [less ▲]

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See detailQuelques réflexions méthodologiques sur les abandons de sanctuaires en Grèce antique
Palamidis, Alaya ULiege

in Revue de l'Histoire des Religions (in press)

Given the limited number of written sources about the disappearance of cults in ancient Greece, as well as the important difficulties raised by their interpretation, the study of this phenomenon is almost ... [more ▼]

Given the limited number of written sources about the disappearance of cults in ancient Greece, as well as the important difficulties raised by their interpretation, the study of this phenomenon is almost exclusively possible through the analysis of the information obtained from archaeological excavations. However, the identification of the abandonment of a sanctuary is often difficult, mainly because of the excavation conditions but also because of post-depositional processes that may cause a destruction of the upper stratigraphic layers. Moreover, the cult of an abandoned sanctuary can be transferred into a new sanctuary, so that the archaeological sources cannot be sufficient to attest the disappearance of a cult. [less ▲]

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See detailArrêt(s) sur image(s) : usages et pratiques du photogramme
Thonon, Jonathan ULiege

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

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See detailsynthéticité et intuition en mathématiques contemporaines : Kant au-delà de Kant
Mazurkiewicz, Stany ULiege

in Eikasia. Revista de Filosofia. (in press)

Ce texte entend réévaluer l'idée de "pure synthèse intellectuelle" que l'on trouve chez Kant. Celle-ci cadre avec la pratique mathématique et métamathématique postérieure à Kant. Elle permet de dépasser l ... [more ▼]

Ce texte entend réévaluer l'idée de "pure synthèse intellectuelle" que l'on trouve chez Kant. Celle-ci cadre avec la pratique mathématique et métamathématique postérieure à Kant. Elle permet de dépasser l'alternative entre l'intuitionnisme développé dans la Critique de la raison pure et la fondation de la mathématique sur une logique formelle analytique. Je montre que cette idée convient à Bolzano et à Dedekind, dont je soutiens que les projets sont irréductibles à du logicisme et qui sont dès lors bien plus "kantiens" qu'il n'y paraît. [less ▲]

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See detailMesurer les distances entre des textes pré-carolingiens linguistiquement non-normés: le cas de la Passion de sainte Marine
Goullet, Monique; Philippart de Foy, Caroline ULiege

in Etudes Classiques (Namur, Belgium) (in press)

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See detailTwo-loop-induced neutrino masses: A model-independent perspective
Aristizabal Sierra, Diego ULiege

in PoS - Proceedings of Science (in press)

We disucuss Majorana neutrino mass generation mechanisms at the two-loop order. After briefly reviewing the systematic classification of one-loop realizations, we then focus on a general two-loop ... [more ▼]

We disucuss Majorana neutrino mass generation mechanisms at the two-loop order. After briefly reviewing the systematic classification of one-loop realizations, we then focus on a general two-loop classification scheme which provides a model-independent catalog for neutrino mass models at the two-loop order [less ▲]

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See detailL’emblématique de Louise de Savoie
Fagnart, Laure ULiege; Girault, Pierre-Gilles

in Armas e Troféus. Rivista de Historia, Heraldica, Genealogia (in press)

A l'occasion de cette étude, à la suite des travaux d'Anne-Marie Lecoq (1987), nous sommes revenus sur le discours héraldique de la comtesse et duchesse d'Angoulême, Louise de Savoie, l'influente mère de ... [more ▼]

A l'occasion de cette étude, à la suite des travaux d'Anne-Marie Lecoq (1987), nous sommes revenus sur le discours héraldique de la comtesse et duchesse d'Angoulême, Louise de Savoie, l'influente mère de François Ier. Nous avons présenté et explicité ses devises favorites, à savoir la cordelière, qui évoque autant le nœud de Savoie que la cordelière franciscaine, le vol, sans doute choisi puisque l’aile évoque le L de Louise par homophonie, le bouquet de lis ou le cygne « navré », mais aussi les écus et les monogrammes qui lui sont associés et qui ponctuent enluminures, tapisseries, bas-reliefs et éléments sculptés de l’architecture. Notre intention a été de montrer d’une part comment Louise de Savoie manifeste, par l’intermédiaire de ces signes emblématiques, son identité et son pouvoir, d’autre part comment elle construit, par leur biais, un patrimoine, mental, susceptible de renforcer son clan et ses héritiers. [less ▲]

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See detailDonnées des bases latines du LASLA et classification générique
Longrée, Dominique ULiege

in Les Etudes Classiques (in press)

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See detailPaper Formats of the Mamluk Period: The Contribution of Mamluk Chancery Paper
Bauden, Frédéric ULiege

in Journal of Islamic Manuscripts (in press)

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See detailQuatre configurations pour créer une dynamique interactive entre formation et recherche Expériences dans le domaine de la formation des professionnels de la santé
Faulx, Daniel ULiege; Burlet, Géraldine ULiege; Bernard, Nicolas ULiege et al

in Recherches Qualitatives (in press)

Dans cette contribution, nous nous penchons sur la possibilité de créer une dynamique interactive entre intervention sur le terrain et recherche scientifique dans le domaine de la formation. Les terrains ... [more ▼]

Dans cette contribution, nous nous penchons sur la possibilité de créer une dynamique interactive entre intervention sur le terrain et recherche scientifique dans le domaine de la formation. Les terrains d’application se situent tous ici dans le domaine de la santé. Nous présentons quatre configurations d’une telle complémentarité. Chacune d’entre elles représente une articulation différente entre le but de développement des participants et celui de production de savoirs scientifiques. Dans le premier cas, une démarche de recherche est entreprise en amont de la conception d’une formation. La deuxième configuration illustre une recherche scientifique appliquée à un dispositif d’intervention existant et qui vient en retour en modifier la logique. Pour la troisième, il s’agit d’une articulation continue entre recherche et formation s’alimentant mutuellement dans une logique de recherche-action. Enfin, la quatrième partie se penche sur trois dispositifs pédagogiques dont la caractéristique est de combiner des intentions formatives avec des préoccupations de recherche [less ▲]

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See detailLa ceramica della Schola del Traiano a Ostia Antica
Deru, Xavier ULiege; Desbat, Armand; Dienst, Simon ULiege et al

in Forum Romanum Belgicum (in press)

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See detailThe role of conservators: an international survey on conservation within contemporary art collections
D'Haenens, Manon ULiege

in CeROArt : Conservation, Exposition, Restauration d'Objets d'Art (in press)

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See detailCross-cultural adaptation and validation of the Patient-Rated Tennis Elbow Evaluation Questionnaire on lateral elbow tendinopathy for French-speaking patients
Kaux, Jean-François ULiege; Croisier, Jean-Louis ULiege; Bruyère, Olivier ULiege

in Journal of Rehabilitation Medicine (in press)

Introduction: The lateral elbow tendinopathy is a common injury in tennis players and physical workers. The Patient- Rated Tennis Elbow Evaluation (PRTEE) Questionnaire was specifically designed to ... [more ▼]

Introduction: The lateral elbow tendinopathy is a common injury in tennis players and physical workers. The Patient- Rated Tennis Elbow Evaluation (PRTEE) Questionnaire was specifically designed to measure pain and functional limitations in patients with lateral epicondylitis. The aims were to adapt the PRTEE questionnaire into French (PRTEE-F) and to evaluate the reliability and validity of this translated version of the questionnaire . Methods: The PRTEE was translated and cross-culturally adapted into French according to international guidelines. To assess the reliability and validity of the PRTEE-F, 115 participants were asked twice to fill in the PRTEE-F, and once the DASH and the SF-36. Internal consistency (using Cronbach’s alpha), test-retest reliability (using intraclass correlation coefficient (ICC), standard error of measurement and minimal detectable change), and convergent and divergent validity (using the Spearman’s correlation coefficients respectively with the DASH and with some subscales of the SF-36) were assessed. Results: The PRTEE was translated into French without any problems. PRTEE-F showed a good test-retest reliability for the overall score (ICC 0.86) and for each item (ICC 0.8-0.96) and a high internal consistency (Cronbach’s alpha 1⁄4 0.98). The correlation analyses revealed high correlation coefficients between PRTEE-F and DASH (convergent validity) and, as expected, a low or moderate correlation with the divergent subscales of the SF-36 (discriminant validity). There was no floor or ceiling effect. Discussion and Conclusions: The PRTEE questionnaire was successfully cross-culturally adapted into French. The PRTEE-F is reliable and valid for evaluating French-speaking patients with lateral elbow tendinopathy. [less ▲]

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See detailValidity and reliability of the French translation of the VISA-A questionnaire
Kaux, Jean-François ULiege; Croisier, Jean-Louis ULiege; Bruyère, Olivier ULiege

in Journal of Rehabilitation Medicine (in press)

Introduction: The Victorian Institute of Sport Assessment – Achilles tendinopathy questionnaire (VISA-A) evaluates the clinical severity of Achilles tendinopathy. The aim of this study was to translate ... [more ▼]

Introduction: The Victorian Institute of Sport Assessment – Achilles tendinopathy questionnaire (VISA-A) evaluates the clinical severity of Achilles tendinopathy. The aim of this study was to translate the VISA-A into French and to study the reliability and validity of this French version, the VISA-AF.Method: The VISA-A was translated into French to produce the VISA-AF using a validated methodology in six steps. Thereafter, several psychometric properties of this French version such as test–retest reliability, internal consistency, construct validity and floor and ceiling effects were evaluated. Therefore, we recruited 116 subjects, distributed into 3 groups: pathological patients (n=31), at-risk athletes (n=63) and healthy people (n=22). Results: The final version of the VISA-AF was approved by an expert committee. On a scale ranging from 0 to 100, the average scores of the VISA-AF obtained were 59 (± 18) for the pathological group, 99 (± 1) for the healthy group and 94 (± 7) for the at-risk group. The VISA-AF shows excellent reliability, low correlations with the discriminant subscales of the SF-36 and moderate correlations with the convergent subscales of the SF-36. Conclusions: The French version of the VISA-A is equivalent to its original version and is a reliable and valid questionnaire for French- speaking patients with Achilles tendinopathy. [less ▲]

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See detailCross-cultural adaptation and validation of the Kujala Anterior Knee Pain Scale (AKPS) questionnaire for French-speaking patients
Kaux, Jean-François ULiege; Buckinx, Fanny ULiege; Croisier, Jean-Louis ULiege et al

in Journal of Rehabilitation Medicine (in press)

Introduction: The femoropatellar syndrom is one of the most common knee problem observable. The Kujala Anterior Knee Pain Scale (AKPS) is a questionnaire used to examine the subjective symptoms, such as ... [more ▼]

Introduction: The femoropatellar syndrom is one of the most common knee problem observable. The Kujala Anterior Knee Pain Scale (AKPS) is a questionnaire used to examine the subjective symptoms, such as the functional limitations and the anterior knee pain. Objective: The aims of the study were to translate and cross-culturally adapt the AKPS questionnaire into French and to evaluate the reliability and validity of this translated version of the questionnaire (AKPS- F). Patients : 101 patients with femoropatellar syndrom. Methods: The translation and the inter-cultural adaptation of the questionnaire has been adopted through the international recommendations highlighting 6 different steps : initial translation, translations synthesis, translation back to the original language, committee of experts, test of the pre-final version and the approval from the expert’s committee. Indeed the French version obtained, the participants have filled twice the AKPS with an interval of 7 days, and the Short Form Health in order to evaluate the psychometric properties (the internal coherence, the test-retest fidelity and the built validity). Results:The AKPS shows a high level of fidelity in the test-retest with a score of 0.97. The French translation also has a high internal coherence score with 0.87. The Kujula shows a great correlation with a part of the converging sub-scales from the SF36. There is a low/average correlation noticeable with the diverging sub-scales. There is no floor/ceiling effect. Discussion and conclusions: This study shows that AKPS-F is reliable and valid for the French patients suffering from a femoropatellar syndrom and can therefore be used. [less ▲]

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See detailMuscle strength profile of patients with patellar tendinopathy
Kaux, Jean-François ULiege; Libertiaux, Vincent ULiege; Croisier, Jean-Louis ULiege

in Journal of Rehabilitation Medicine (in press)

Introduction: Patellar tendinopathy (PT) is commonly observed in jumping sports. Even if its biomechanic is somewhat explored, no information is known about the muscle strength profile of these patients ... [more ▼]

Introduction: Patellar tendinopathy (PT) is commonly observed in jumping sports. Even if its biomechanic is somewhat explored, no information is known about the muscle strength profile of these patients. Objective: To determine if there exists a specific profile of patients suffering from a PT. Patients: 43 patients (29+/-9.8 y.o) suffering from PT were recruited. To be eligible, the patients must not have suffered from any other traumatic or micro-traumatic injury than the PT on the pathologic limb. Methods: After a physical examination, the tendon damage was assessed by ultrasounds examination. The patients were then tested on an isokinetic dynamometer and the maximum torque (per unit of mass, MTm) developed by the quadriceps and the hamstrings were recorded for various angular velocities. After each test, a visual analog scale (VAS) was used to estimate the pain felt by the patients. Results: No significant correlation was found between the MTm and the demographic variables. The difference in MTm between the healthy and the pathological limbs was significant only at a rate of 60°/s, for both the quadriceps and the hamstrings. Lastly, the VAS score showed that the most intense pain was experienced after the eccentric test. Conclusions: There is no clear patient strength profile emerging from the isokinetic test. This stresses the importance for the clinicians to make testing and to apply a personalized treatment to each patient. Finally, the isokinetic eccentric testing of the quadriceps can be used to induce a mechanical stress on the tendon for a reliable pain assessment. [less ▲]

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See detailComparison of the effect of Platelet Rich Plasma (PRP) with Hyaluronic Acid (HA) injections to treat chronic Jumper's knee
Kaux, Jean-François ULiege; DEROISY, Rita ULiege; SAMSON, Antoine ULiege et al

in Journal of Rehabilitation Medicine (in press)

Introduction: Patellar Tendinopathies (PT) represent a very frequent disorder which incidence can reach 30-50% among jumping sports. This trouble is often rebel to classical treatment. Objective: To ... [more ▼]

Introduction: Patellar Tendinopathies (PT) represent a very frequent disorder which incidence can reach 30-50% among jumping sports. This trouble is often rebel to classical treatment. Objective: To compare the efficacy of a single injection of RPR to a double infiltration of HA at one week interval. Patients/Methods: Thirty-three patients suffering from PT were enrolled into the study and split into two randomized groups . Eighteen patients (Group 1) have received one PRP injection and the other fifteen subjects (Group 2) received two HA infiltrations. Pain and functionality of the knee were evaluated before injection (T0), 6 weeks (T2) and 3 months (T3) after injections: pain with VAS and pressure algometer, algofunctional scores with IKDC and VISA-P questionnaires, ultrasound, isokinetic evaluation (quadriceps contractions : concentric 60°/sec (C60), concentric 240°/sec (C240), excentric 30°/sec (E30) and VAS during testing). Results: At baseline, difference existed only between groups for algometer, tendon thickness and axial hypoechoic area. In both groups, VAS, algometer, IKCD, VISA-P, VAS for isokinetic testing C60, C240 and E30 were significantly improved at T2 and T3 compared to T0. Comparison between the 2 groups showed no difference excepted for algometer, tendon thickness (T2, T3) and axial hypoechoic area (T2). Discussion and conclusions: There existed a similar improvement of the symptoms in both groups. PRP has already shown its efficacy in PT. HA should probably be a new therapeutic opportunity in this indication. Nevertheless, it should better, for further studies, to include a more homogeneous population and a longer follow-up period of time. [less ▲]

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See detailTranslation and Validation of the VISA-P Questionnaire for French-Speaking Patients
Kaux, Jean-François ULiege; DELVAUX, François ULiege; Oppong-Kyei, Julian et al

in Journal of Rehabilitation Medicine (in press)

Background: The Victorian Institute of Sport Assessment-Patella (VISA-P), originally developed in English, assesses the severity of patellar tendinopathy symptoms. To date, no French version of the ... [more ▼]

Background: The Victorian Institute of Sport Assessment-Patella (VISA-P), originally developed in English, assesses the severity of patellar tendinopathy symptoms. To date, no French version of the questionnaire exists. Objectives: The aim of our study was to translate the VISA-P into French and verify its psychometric properties. Methods: The translation and cultural adaptation were performed according to international recommendations in 6 steps: initial translation, translation merging, back translation to the original language, use of an expert committee to reach a prefinal version, test of the prefinal version, and expert committee appraisal of a final version. Afterward, the psychometric properties of the final French version (VISA-PF) were assessed in 92 subjects, divided into 3 groups: pathological subjects (n = 28), asymptomatic subjects (n = 22), and sports-risk subjects (n = 42). Results: All members of the expert committee agreed with the final version. On a scale ranging from 0 to 100, with 100 representing an asymptomatic subject, the average SD scores on the VISA-PF were 53 17 for the pathological group, 99 2 for the healthy group, and 86 14 for the sports-risk group. The test-retest reliability of the VISA-PF was excellent, with good internal consistency. Correlations between the VISA-PF and divergent validity of the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) were low, and the correlation coefficient values measured between the VISA-PF scores and converged items of the SF-36 were higher. Conclusion: The VISA-PF is understandable, valid, and suitable for French-speaking patients with patellar tendinopathy. [less ▲]

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See detailNeuro-functional correlates of the protective effects of exercise against cocaine sensitization and dopamine D2 receptors density: a [18F]Fallypride microPET study.
Becker, Guillaume ULiege; Lespine, Louis-Ferdinand ULiege; Serrano Navacerrada, Maria Elisa ULiege et al

in Molecular Imaging & Biology (in press)

Preclinical studies suggest that free access to a running wheel can attenuate behavioural effects of addictive drugs such as psychomotor sensitization to cocaine in rodents. This phenomenon has an ... [more ▼]

Preclinical studies suggest that free access to a running wheel can attenuate behavioural effects of addictive drugs such as psychomotor sensitization to cocaine in rodents. This phenomenon has an integral role in the process of drug addiction in craving and relapse (Steketee and Kalivas, 2011). Free wheel-running was recently shown to be efficacious at preventing the initiation or the long-term expression of psychomotor sensitization to cocaine in mice or rats (Diaz et al., 2013; Geuzaine and Tirelli, 2014). In the present study, we investigated the neuro-functional correlates of the protection against psychomotor sensitization to cocaine afforded by free wheel-running on dopaminergic neurotransmission, using microPET imaging with [18F]Fallypride, a Dopamine 2 receptor (D2R) antagonist. Sixty-four 28-day-old female C57BL/6J mice were randomly assigned to one of the two housing conditions, defined by the presence or the absence of a running wheel in the cage over a 6-week pre-testing period. Since mice from the two types of housing received either saline (controls) or cocaine (8 mg/kg, i.p.) during testing (9 once-daily sessions to establish sensitization plus 1 single session to test its expression), a basic 2x2 randomized blocks design was generated (2-way ANOVA and planned comparisons; n=10). Experimentation lasted 85 days, with a 42-day period of pre-testing and a 3-week interval preceding the test for long-term expression of sensitization (LTES). All mice underwent a microPET (Focus 120, Siemens) the day after the LTES. The microPET protocol consisted of a 60 min. dynamic acquisition after the injection of 10 MBq of [18F]Fallypride in the tail vein. Wheel-running strongly and significantly attenuated LTES (interaction) to cocaine (Cohen’s d=1.63; t(21)=3.75, p<.001) and cocaine-treated mice exhibited a clear-cut and significant increase (main effect) of the [18F]Fallypride BP (d=0.88, t(31)=2.45, p =.02). Wheel-running induced an overall moderate-sized decrease (main effect) of the [18F]Fallypride BP, but without achieving statistical significance (d=0.64, t(31)=1.79, p =.08). These findings suggest that LTES is associated with an increase of the [18F]Fallypride BP in the mouse striatum, probably reflecting an increase in postsynaptic D2R density in this region. Also, the protecting effect of free running on psychomotor sensitization goes together with a decrease in D2R density in the striatum of exercised mice. We intend to complement the present study with an identical experiment to reach a total number of 80 mice (n=20). This will confer to our study a sufficient power (80%) for the main effect of wheel-running exercise on [18F]Fallypride BP to be detected at an alpha-level of 5%. Finally, autoradiography studies, performed on the same mice with [18F]Fallypride, will strengthen our in vivo results. [less ▲]

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See detailFrench Translation and validation of the Exercise-Induced Leg Pain
Kaux, Jean-François ULiege; Hagelstein, Thibaut; Van Beveren, Julien et al

in British Journal of Sports Medicine (in press)

Objective: The « Exercise-Induced Leg Pain » (EILP) questionnaire has been developed (in German) to evaluate the severity of symptoms and sports ability in individuals with exercise-induced leg pain. The ... [more ▼]

Objective: The « Exercise-Induced Leg Pain » (EILP) questionnaire has been developed (in German) to evaluate the severity of symptoms and sports ability in individuals with exercise-induced leg pain. The purpose of the present study was to translate and cross-culturally adapt this questionnaire into French and to study the reliability and validity of the French-translated version (EILP-F). Methods: Translation and cross-culturally adaptation of the original EILP (EILP-G) was performed according to established guidelines. The translation part was articulated in six stages: (i) two initial translations from German to French; (ii) synthesis of the two translations; (iii) backward translations; (iv) expert committee to compare the backward translations with the original questionnaire; (v) pre-test; and (vi) approval of the final version of the EILP-F. To validate the EILP-F questionnaire, 84 subjects were recruited (28 pathological patients with a confirmed diagnosis of chronic leg pain, 28 asymptomatic sport students, 28 athletes healthy control). Discriminative power of the questionnaire was tested as well as reliability (internal consistency, test–retest reliability after a 7-10-day interval), construct validity and floor/ceiling effects. Results: the EILP-F version of the questionnaire has been generated without any major difficulties. The ability of the questionnaire to discriminate the three groups of subjects has been showed with a total score of 61.0 ± 18.5 for the pathologic group; 93.9 ± 7.57 for the asymptomatic group and 94.1 ± 9.79 for the control group (p-value adjusted on age = 0.008). A high internal consistency (Cronbach's alpha of 0.93) and an excellent test-retest radiality (ICC of 0.98 (95% CI 0.97-0.99, p<0.001)) indicated that the EILP-F is reliable. The EILP-F also demonstrated a good construct validity against different subscales of the Short Form-36 questionnaire, a generic quality of life questionnaire, with more than 87 % of prespecified hypotheses confirmed. Finally, no floor or ceiling effects were observed. Conclusion: The EILP-F questionnaire, a French version adapted from the original EILP-G, was successfully translated and cross-culturally adapted. The EILP-F questionnaire is consistent, valid and reliable for evaluating the French-speaking patients with chronic exercise-induced leg pain. [less ▲]

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See detailFrench translation and validation of the AKPS questionnaire
Buckinx, Fanny ULiege; Remy, Gaël; Bornheim, Stephen ULiege et al

in British Journal of Sports Medicine (in press)

Introduction: The Anterior Knee Pain Scale (AKPS) is a questionnaire used to examine the subjective symptoms, such as the functional limitations and the anterior knee pain. First developed in English ... [more ▼]

Introduction: The Anterior Knee Pain Scale (AKPS) is a questionnaire used to examine the subjective symptoms, such as the functional limitations and the anterior knee pain. First developed in English, this questionnaire has since been translated and validated into several languages. The aims of the study were to translate and cross-culturally adapt the AKPS into French and to evaluate the reliability and validity of this translated version of the questionnaire. Methods: The translation part was articulated in six stages, according to international guidelines: (i) two initial translations from english to french; (ii) synthesis of the two translations; (iii) backward translations into the original language; (iv) expert committee to compare the backward translations with the original questionnaire (v) pre-final version testing and (VI) expert committee appraisal. To validate the French AKPS questionnaire, we assessed its validity, reliability and floor/ceiling effects. To do this, volunteer patients from Belgium and France, with patellofemoral pain syndrome were asked to answer the french version of the AKPS questionnaire at baseline and after 7 days, as well as the generic SF-36 questionnaire. Results: The AKPS questionnaire was translated without any major difficulties. A total of 101 subjects aged 34.49 ± 11.38 years on average were included in this study. Among them, 58.4% were women. Results indicated an excellent test-retest reliability (intraclass coefficient correlation of 0.97, 95% CI 0.96 - 0.98), a high internal consistency (Cronbach’s alpha of 0.87), a consistent construct validity (high correlations with the SF-36 questionnaire were found with domains related to physical function (r = 0.80), physical role (r = 0.70), pain (r = 0.64)) and low or moderate correlations with domains related to mental health (r = 0.26), vitality (r = 0.32), social function (r = 0.41)). Moreover, no floor/ceiling has been found. Conclusion: A valid AKPS french questionnaire is now available and can be used with confidence to better assess the disease burden associated with femoropatellar syndrom. It was successfully cross-culturally adapted into French. [less ▲]

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See detailComparison of Platelet Rich Plasma (PRP) versus Hyaluronic Acid (HA) injections to treat patellar tendinopathies
Kaux, Jean-François ULiege; Roberjot, Mathieu; SAMSON, Antoine ULiege

in British Journal of Sports Medicine (in press)

Introduction: The treatment of patellar tendinopathies could be difficult. Recent systematic review concluded that PRP could be recommend as a treatment in such indication. Recently, the viscoelastic ... [more ▼]

Introduction: The treatment of patellar tendinopathies could be difficult. Recent systematic review concluded that PRP could be recommend as a treatment in such indication. Recently, the viscoelastic properties of hyaluronic acid (HA) on liquid connective tissue have been proposed for the treatment of tendinopathies. Some observations also support its use in a clinical setting to improve pain and function. We aimed to compare the effect of PRP injection versus two injections of HA after three months on patients who have a proximal patellar tendinopathy. Methods: Thirty-three sportsmen with proximal patellar tendinopathies being not relieved after minimum three months of normal physiotherapy treatments where included. Eighteen of them (group 1) have received a leukocyte poor PRP injection (obtained using an aphaeresis machine (3)) and the other fifteen (group 2) two HA injections, all of them have benefited of standardized rehabilitation. Concerning the evaluation of the pathology, algo-functional tests (visual analogic scale (VAS), pressure algometer, IKDC score, VISA-P score), isokinetic (associated to VAS) along with the patellar tendon ultrasonography (US) have been realized over three times (pre-injection, after 6 weeks, after 3 months post-injections). Results: The results of VAS (p<0,01), algometric scores (p<0,01), IKDC scores (p<0,01) and VISA-P (p<0,01) show a considerable improvement in the two groups, but not for the US findings. For the group 1, isokinetic tests show significative results for the hamstrings in C60°/s with an improvement of maximum peak torque (p=0,01) for the pathological member, a diminution (p>0,05) for the healthy limb and during the analysis of the bilateral difference (p=0,0002). For the group 2, the improvement of quadriceps maximum peak torque in C240°/s is significant (p>0,01) for the pathological knee after 6 weeks post-injections only. The VAS associated with isokinetic tests decreases significantly for all contraction modes after three months of study. Conclusion: Both PRP and HA can improve the symptoms of proximal patellar tendinopathy, even if the results are slightly better in the PRP group. [less ▲]

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See detailExploring the effect of a second closely-timed PRP infiltration for tendinopathy
Kaux, Jean-François ULiege; Croisier, Jean-Louis ULiege; Forthomme, Bénédicte ULiege et al

in British Journal of Sports Medicine (in press)

Introduction: Some clinical series have previously evaluated the effect of PRP in the treatment of proximal patellar tendinopathies. Although it is possible that a single infiltrative administration may ... [more ▼]

Introduction: Some clinical series have previously evaluated the effect of PRP in the treatment of proximal patellar tendinopathies. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of successive infiltrations which is arguably likely to increase the risks of complications. Methods: Our study is a single blinded, randomized controlled clinical trial on 20 leisure sportsmen (2 groups, respectively 1 or 2 infiltrations of pure PRP) with chronic proximal patellar tendinopathies, rebel to classical management. PRP was obtained using an aphaeresis machine. The one-year follow-up evaluation consisted of VAS, IKDC and VISA-P scores, while algometer, isokinetic and ultrasounds evaluations were carried out up to 3 months. Results: The concentration of the PRP used was similar in both groups. The VAS significantly decreased with time over the 3-month follow-up period (p=0.002), with no difference observed between the two groups (p=0.2). Values obtained with the pressure algometer increased with time across both groups over the 3-month follow-up period (p<0.0001), and values were significantly higher for Group 1 (p=0.001). The IKDC score increased with time in both groups over the follow-up period (p=0.034), with values again significantly higher for Group 1 (p=0.0026). The VISA-P score increased with time in both groups over the follow-up period (p=0.0023), with no difference observed between the groups (p=0.41). No improvements in isokinetic physical performance were observed in either group. However, pain during E30 significantly decreased over the 3-month follow-up period (p=0.027) for patients in both groups. No improvement in either jumping performances or in pain was observed in either group during opto-jump evaluation. No improvements in US findings were observed. After one year, 90% patients of group 1 did not report anymore pain during daily activities, in comparison with only 20% in group 2. Conclusions: A second closely-timed infiltration of PRP to treat proximal patellar tendinopathies is not necessary to improve the efficacy of this treatment. [less ▲]

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See detailCross-cultural adaptation in French and validation of Functional Assessment Scale for acute Hamstring injuries
Kaux, Jean-François ULiege; Willems, Tom; Locquet, Médéa ULiege

in British Journal of Sports Medicine (in press)

Introduction : Acute hamstring injury is a very common muscle injury particularly in sports that require high explosive strength, sports with impulsions and sports with running phases. Among those sports ... [more ▼]

Introduction : Acute hamstring injury is a very common muscle injury particularly in sports that require high explosive strength, sports with impulsions and sports with running phases. Among those sports, the most widespread are soccer, rugby and sprinting. The Functional Assessment Scale for acute Hamstring injuries (FASH) assesses pain, physical activity and how patients realize some exercises while suffering hamstring injury. Current available versons are in English, in German and in Greek. Objectives : The aims of thus study were to reach a reliable and valid translation and a cross-cultural adaptation of this questionnaire in French. Methods: FASH translation and adaptation were realized in respect of international guidelines. The population composed of 116 subjects filled the questionnaire twice separated by 48-60th. FASH reliability and validity were assessed thanks to SF-36 allowing us to assess the test re-test reliability (with intra-class correlation ICC), internal consistency (with Cronbach’s alpha coefficient and construct validity, with Spearman’s correlation coefficients). Results : ICC showed a strong correlation between test and re-test (ICC total=0.9985). Internal consistency was also found to be strong with Cronbach’s alpha coefficient = 0.98. Correlation between FASH and SF-36 overall score was considered as strong (Rs=0.69, p<0.0001). Correlation with SF-36 sub scales (PF, RP, BP) were also considered as strong, showing their convergent validity. Other SF-36 subclass (GH, MH, REm, SF, VT) displayed a moderate correlation with FASH questionnaire, showing their divergent validity. No floor or ceiling effect was observed. Conclusions: FASH translation and cross-cultural adaptation into French can be considered as successful. FASF-F is now a reliable and valid tool for patients suffering acute hamstring injury. [less ▲]

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See detailIsokinetic profile of subjects with proximal patellar tendinopathy
Kaux, Jean-François ULiege; Croisier, Jean-Louis ULiege; Libertiaux, Vincent ULiege

in British Journal of Sports Medicine (in press)

Introduction Patellar tendinopathy (PT) is commonly observed in jumping sports. Even if its biomechanic is somewhat explored, no information is known about the muscle strength profile of these patients ... [more ▼]

Introduction Patellar tendinopathy (PT) is commonly observed in jumping sports. Even if its biomechanic is somewhat explored, no information is known about the muscle strength profile of these patients. We aimed to determine if there exists a specific profile of patients suffering from a PT Methods 43 patients (42 males; 29 y.o +/- 9.8 y.o) suffering from PT were recruited. To be eligible, the patients must not have suffered from any other traumatic or micro-traumatic injury than the PT on the pathologic limb. After a physical examination, the tendon damage was assessed by ultrasounds examination. The patients were then tested on an isokinetic dynamometer and the peak torque per unit of mass (PTm) developed by the quadriceps and the hamstrings were recorded for various testing modalities. After each test, a visual analog scale (VAS) was used to estimate the pain felt by the patients. Results No significant correlation was found between the MTm and the demographic variables. The difference in MTm between the healthy and the pathological limbs was significant only in concentric 60°/s, for both the quadriceps and the hamstrings. Lastly, the VAS score showed that the most intense pain was experienced after the eccentric test. Conclusions There is no specific patient strength profile emerging from the isokinetic test. This stresses the importance for the clinicians to make testing and to apply a personalized treatment to each patient. On the other hand, the isokinetic eccentric testing of the quadriceps could be used to induce a mechanical stress on the tendon for a reliable pain assessment. [less ▲]

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See detailDiscovering Routers in Load-balanced Paths
Grailet, Jean-François ULiege; Donnet, Benoît ULiege

in 13th International Conference on emerging Networking EXperiments and Technologies Student Workshop (2017, December 12)

Usually, a set of Traceroute measurements collected for a large amount of target IPs contain one or several route hops at which the IP interfaces vary from one measurement to another. These variations ... [more ▼]

Usually, a set of Traceroute measurements collected for a large amount of target IPs contain one or several route hops at which the IP interfaces vary from one measurement to another. These variations occur even if several measurements share the same length and the same last hops. This is likely a consequence of load balancing, a traffic engineering policy which aims at sharing the load to ensure quality of service. In this paper, we consider the problem of conducting alias resolution on IP interfaces discovered via Traceroute and which are involved in load balancing. By conducting alias resolution in such a context, we want to verify if the IP interfaces involved in load balancing belong to unique routers, and more broadly, how relevant is alias resolution in this context. To do so, we use a slightly edited version of TreeNET, a topology discovery tool which relies on a tree-like structure based on Traceroute measurements to map a target domain. The upgraded TreeNET along the measurements described in this paper are both freely available online. [less ▲]

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See detailAn Observation-Based Middlebox Policy Taxonomy
Edeline, Korian ULiege; Donnet, Benoît ULiege

in 13th International Conference on emerging Networking EXperiments and Technologies Student Workshop (2017, December 12)

Recent years have seen the rise of middleboxes, such as NATs, firewalls, or TCP accelerators. Those middleboxes play an important role in today's Internet, including enterprise networks and cellular ... [more ▼]

Recent years have seen the rise of middleboxes, such as NATs, firewalls, or TCP accelerators. Those middleboxes play an important role in today's Internet, including enterprise networks and cellular networks. However, despite their undisputable success in modern network architecture, their actual impact on packets, traffic, and network performance is not that much understood. In this paper, we propose a path impairment oriented middlebox classification that aims at categorizing the initial purpose of a middlebox policy as well as its potential complications. [less ▲]

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See detailThrough the Wormhole: Tracking Invisible MPLS Tunnels
Vanaubel, Yves ULiege; Mérindol, Pascal; Pansiot, Jean-Jacques et al

in ACM Internet Measurement Conference (2017, November)

For years, Internet topology research has been conducted through active measurement. For instance, CAIDA builds router level topologies on top of IP level traces obtained with traceroute. The resulting ... [more ▼]

For years, Internet topology research has been conducted through active measurement. For instance, CAIDA builds router level topologies on top of IP level traces obtained with traceroute. The resulting graphs contain a significant amount of nodes with a very large degree, often exceeding the actual number of interfaces of a router. Although this property may result from inaccurate alias resolution, we believe that opaque MPLS clouds made of invisible tunnels are the main cause. Using Layer-2 technologies such as MPLS, routers can be configured to hide internal IP hops from traceroute. Consequently, an entry point of an MPLS network appears as the neighbor of all exit points and the whole Layer-3 network turns into a dense mesh of high degree nodes. This paper tackles three problems: the revelation of IP hops hidden by MPLS tunnels, the MPLS deployment underestimation, and the overestimation of high degree nodes. We develop new measurement techniques able to reveal the presence and content of invisible MPLS tunnels. We assess them through emulation and cross-validation and perform a large-scale measurement campaign targeting suspicious networks on which we apply statistical analysis. Finally, based on our dataset, we look at basic graph properties impacted by invisible tunnels. [less ▲]

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See detailMODEL FOR REASONING FROM SEMANTICALLY RICH POINT CLOUD DATA
Poux, Florent ULiege; Neuville, Romain ULiege; Hallot, Pierre ULiege et al

in ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences (2017, October 26), IV-4/W5

This paper proposes an interoperable model for managing high dimensional point clouds while integrating semantics. Point clouds from sensors are a direct source of information physically describing a 3D ... [more ▼]

This paper proposes an interoperable model for managing high dimensional point clouds while integrating semantics. Point clouds from sensors are a direct source of information physically describing a 3D state of the recorded environment. As such, they are an exhaustive representation of the real world at every scale: 3D reality-based spatial data. Their generation is increasingly fast but processing routines and data models lack of knowledge to reason from information extraction rather than interpretation. The enhanced smart point cloud developed model allows to bring intelligence to point clouds via 3 connected meta-models while linking available knowledge and classification procedures that permits semantic injection. Interoperability drives the model adaptation to potentially many applications through specialized domain ontologies. A first prototype is implemented in Python and PostgreSQL database and allows to combine semantic and spatial concepts for basic hybrid queries on different point clouds. [less ▲]

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See detailTOWARDS A DECISION SUPPORT TOOL FOR 3D VISUALISATION: APPLICATION TO SELECTIVITY PURPOSE OF SINGLE OBJECT IN A 3D CITY SCENE
Neuville, Romain ULiege; Pouliot, Jacynthe; Poux, Florent ULiege et al

in ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences (2017, October 26), IV-4/W5

This paper deals with the establishment of a comprehensive methodological framework that defines 3D visualisation rules and its application in a decision support tool. Whilst the use of 3D models grows in ... [more ▼]

This paper deals with the establishment of a comprehensive methodological framework that defines 3D visualisation rules and its application in a decision support tool. Whilst the use of 3D models grows in many application fields, their visualisation remains challenging from the point of view of mapping and rendering aspects to be applied to suitability support the decision making process. Indeed, there exists a great number of 3D visualisation techniques but as far as we know, a decision support tool that facilitates the production of an efficient 3D visualisation is still missing. This is why a comprehensive methodological framework is proposed in order to build decision tables for specific data, tasks and contexts. Based on the second-order logic formalism, we define a set of functions and propositions among and between two collections of entities: on one hand static retinal variables (hue, size, shape…) and 3D environment parameters (directional lighting, shadow, haze…) and on the other hand their effect(s) regarding specific visual tasks. It enables to define 3D visualisation rules according to four categories: consequence, compatibility, potential incompatibility and incompatibility. In this paper, the application of the methodological framework is demonstrated for an urban visualisation at high density considering a specific set of entities. On the basis of our analysis and the results of many studies conducted in the 3D semiotics, which refers to the study of symbols and how they relay information, the truth values of propositions are determined. 3D visualisation rules are then extracted for the considered context and set of entities and are presented into a decision table with a colour coding. Finally, the decision table is implemented into a plugin developed with three.js, a cross-browser JavaScript library. The plugin consists of a sidebar and warning windows that help the designer in the use of a set of static retinal variables and 3D environment parameters. [less ▲]

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See detailIsotopic Ratios in a Peculiar Outbursting Comet
Yang, Bin; Hutsemekers, Damien ULiege; Shinnaka, Yoshiharu et al

in Bulletin of the American Astronomical Society (2017, October 01), 49

Isotopic ratios in comets provide keys for the understanding of the origin of cometary material, and the physical and chemical conditions in the early Solar Nebula. A newly discovered peculiar comet, C ... [more ▼]

Isotopic ratios in comets provide keys for the understanding of the origin of cometary material, and the physical and chemical conditions in the early Solar Nebula. A newly discovered peculiar comet, C/2015 ER61, underwent an outburst with a total brightness increase of 2 magnitudes on the night of April 4th, 2017. The sharp increase in brightness offers a rare opportunity to measure the isotopic ratios of the light elements of this comet. We obtained two high-resolution spectra of C/2015 ER61 with UVES on Apr. 13 and Apr. 17 respectively. At the time of our observations, the comet was fading gradually since the outburst. We measured the 12C/13C and 14N/15N isotopic ratios from the CN Violet (0,0) band. In addition, we determined the 14N/15N ratio in NH2 for C/2015 ER61 from four pairs of NH2 isotopologue lines. Some 18OH lines were detected but the S/N of these lines is too low to derive a reliable 18O/16O estimate. We will present our UVES spectra of C/2015 ER61, obtained shortly after the outburst. We will also present the comparison of the Isotopic ratios of C/2015 ER61 with those of other comets. [less ▲]

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See detailWhat CoRoT tells us about δ Scuti stars. Existence of a regular pattern and seismic indices to characterize stars
Michel, Eric; Dupret, Marc-Antoine ULiege; Reese, Daniel et al

in European Physical Journal Web of Conferences (2017, October 01), 160

Inspired by the so appealing example of red giants, where going from a handful of stars to thousands revealed the structure of the eigenspectrum, we inspected a large homogeneous set of around 1860 δ ... [more ▼]

Inspired by the so appealing example of red giants, where going from a handful of stars to thousands revealed the structure of the eigenspectrum, we inspected a large homogeneous set of around 1860 δ Scuti stars observed with CoRoT. This unique data set reveals a common regular pattern which appears to be in agreement with island modes featured by theoretical non-perturbative treatments of fast rotation. The comparison of these data with models and linear stability calculations suggests that spectra can be fruitfully characterized to first order by a few parameters which might play the role of seismic indices for δ Scuti stars, as Δv and v[SUB]max[/SUB] do for red giants. The existence of this pattern offers an observational support for guiding further theoretical works on fast rotation. It also provides a framework for further investigation of the observational material collected by CoRoT ([1]) and Kepler ([2]). Finally, it sketches out the perspective of using δ Scuti stars pulsations for ensemble asteroseismology [less ▲]

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See detailCessation of nucleos(t)ide analogue treatment after HBeAg seroconversion is associated with a 4-fold increased risk of relapse in cirrhotic compared to non-cirrhotic patients
Van Hees, S; Bourgeois, S; Van Vlierberghe, H et al

in Hepatology (Baltimore, Md.) (2017, October), 66(S1), 934

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See detailThe γ Dor stars as revealed by Kepler: A key to reveal deep-layer rotation in A and F stars
Salmon, Sébastien ULiege; Ouazzani, R.-M.; Antoci, V. et al

in EPJ Web of Conferences (2017, September 08), 152

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See detailReliability of a standardized protocol for bedside quadriceps strength measurement in critically ill patients
ROUSSEAU, Anne-Françoise ULiege; Freycenon, Gaëlle ULiege; KELLENS, Isabelle ULiege et al

in Intensive Care Medicine Experimental (2017, September), 5(S2), 327

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See detailAdministration of mesenchymal stromal cells before renal ischemia/reperfusion attenuates kidney injury and modulates renal lipid metabolism in rats
ERPICUM, Pauline ULiege; Rowart, Pascal ULiege; POMA, Laurence ULiege et al

in Transplant International (2017, September), 30(S2), 9004

Background: Mesenchymal stromal cells (MSC) have been demonstrated to attenuate renal ischemia/reperfusion (I/R) damage in rodents. The mecha- nisms of such nephroprotection remain unclear. Materials and ... [more ▼]

Background: Mesenchymal stromal cells (MSC) have been demonstrated to attenuate renal ischemia/reperfusion (I/R) damage in rodents. The mecha- nisms of such nephroprotection remain unclear. Materials and Methods: Male Lewis rats aged of 8–10 weeks received tail i.v injection of 1.5x106 MSC in 1 mL saline (MSCD-7, n = 11) or saline alone (SD- 7, n = 6) 7 days before renal I/R. Left renal ischemia (by clamping the renal pedicle) lasted 45 min. Right nephrectomy was simultaneously performed. Blood sample was collected from inferior vena cava 48 h post reperfusion. Renal function was assessed by measuring serum creatinine (SCr) levels. Expressions of inflammatory and apoptotic markers by real-time (RT)-qPCR were comparatively quantified. High-throughput RNA sequencing was applied to MSCD-7 vs. SD-7 non-ischemic right kidneys. Relevant pathways were detected using an Over-Representation Analysis with WebGestalt, and confirmed by RT-qPCR. Results: Scr levels reached 1.4 ` 0.7 vs. 2.4 ` 0.8 mg/dL in MSCD-7 vs. SD-7 group (p < 0.05). MSC infusion significantly reduced mRNA expression of Casp3, Hsp 70, Kim-1, Mcp-1 and Il-6 and increased mRNA expression of Bcl compared to saline. Among 25 908 genes, 748 were identified as significantly differentially expressed (False Discovery Rate (FDR), <0.05) between MSCD-7 and SD-7 non-ischemic kidneys. Among the most affected metabolic pathways, renal lipid metabolism was significantly altered, with down-regulation of fatty acid biosynthesis and an up-regulation of PPARa pathway in MSCD-7 vs. SD-7 groups. By immunoblotting, PPARa and phosphorylated-PPARa were significantly increased in MSCD-7 vs. SD-7 kidneys, in both non-ischemic and ischemic conditions. Moreover, levels of malondialdehyde-derived lipid peroxidation products were decreased in MSCD-7 ischemic kidneys in comparison to SD-7 ischemic kidneys. Conclusion: MSC infusion at day 7 prior injury critically impacts renal lipid metabolism, which may condition kidney parenchyma against I/R. [less ▲]

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See detailLes modes d'acquisition et de transmission du savoir médical dans l'antiquité gréco-romaine
Marganne, Marie-Hélène ULiege

in Histoire des Sciences Médicales (2017, September), 51(2), 163-173

This paper aims to define and describe the ways of acquiring and transmitting medical knowledge in Greco-Roman Antiquity through an analysis of literary, archaeological, and, primarily, papyrological ... [more ▼]

This paper aims to define and describe the ways of acquiring and transmitting medical knowledge in Greco-Roman Antiquity through an analysis of literary, archaeological, and, primarily, papyrological sources. The methods and practices revealed by these sources include experiment, analogy, and imitation, oral and written teaching, the composition and copying of books (illustrated or not), as well as the elaboration of commentaries, abridgments, questionnaires, and word lists. These modes of knowledge transfer were intended not only for medical practitioners and students, but also for philiatroi, for generally educated people, as well as for scribes, and eventually tachygraphers, of medical books. [less ▲]

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See detailLes références à la maladie et à son traitement dans les archives de Zénon
Ricciardetto, Antonio ULiege

in Histoire des Sciences Médicales (2017, September), LI(2), 153-162

Amongst the 1837 papyri from the archive of Zenon, the private secretary to Apollonius, finance minister to Ptolemy II Philadelphus (285-246 BC), about twenty private Greek letters refer to ailments ... [more ▼]

Amongst the 1837 papyri from the archive of Zenon, the private secretary to Apollonius, finance minister to Ptolemy II Philadelphus (285-246 BC), about twenty private Greek letters refer to ailments suffered either by the sender or the recipient of the letter, or by a third party. How do these letters, which were not written by medical professionals, designate and describe diseases, their evolution and their outcome? This paper attempts to answer this question, while highlighting the contribution of these documents to the history of health and illness in Ptolemaic Egypt. [less ▲]

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See detailDO MESENCHYMAL STROMAL CELLS PROMOTE HLA SPECIFIC ANTIBODIES FORMATION AFTER INFUSION IN LIVER TRANSPLANT RECIPIENTS?
VANDERMEULEN, Morgan ULiege; MAGGIPINTO, Gianni ULiege; JOURET, François ULiege et al

in Transplant International (2017, September), 30(S2), 548051

Background: Mesenchymal stromal cells (MSC) immunogenicity is debated. We recently published a prospective, controlled, phase I study evaluating a single administration of third-party MSC in 10 liver ... [more ▼]

Background: Mesenchymal stromal cells (MSC) immunogenicity is debated. We recently published a prospective, controlled, phase I study evaluating a single administration of third-party MSC in 10 liver transplant recipients (LTR). Here, we focus on the development of antibodies (Ab) against MSC-donor HLA (MSCDSA) in LTR following MSC infusion. Methods: Ten LTR under standard immunosuppression received 3rd-party unrelated MSC on postoperative day 3, and were prospectively compared to 10 control LTR. Recipients and donor of either liver or MSC were genotyped for HLA A/B/C/DR/DQ. Recipients were tested for HLA Ab before and 1, 3 and 6 months after transplant by Luminex". Ab were considered as positive in case of MFI >1500 and in accordance with the manufacturer’s recommendations. Results: In MSC-treated group, 2 patients showed pre-transplant MSCDSA. During follow-up, MSCDSA were detected in 6 additional patients who had received multiple red blood cell allo-transfusions before and/or rapidly after transplant. These patients also developed Ab against various MSC-unrelatedHLA. Two patients did not develop any MSCDSA throughout the follow-up, and one of them did not receive any allo-transfusion. MFI of detected MSCDSA were not significantly different from MFI of other detected HLA Ab. In control group, 3 patients were sensitized pre-transplant, and 6 patients developed de novo multiple HLA Ab. Four of these had received multiple allo-transfusions. Conclusion: In the large pool of HLA Ab identified in LTR post transplant, the detection of MSCDSA is most likely caused by allo-transfusions rather than related to MSC infusion. Further studies are required to confirm that MSC are “immune privileged”. [less ▲]

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See detailSurgical factors and not donor type per se are risk factors for acute kidney injury after liver transplantation
MEURISSE, Nicolas ULiege; Smet, Heloise ULiege; LEDOUX, Didier ULiege et al

in Transplant International (2017, September), 30(S2), 106-107298

Background: Because Liver Transplantation (LT) using DCD has been shown to be risk factor for Acute Kidney Injury (AKI), we reviewed results at our center. Patients and Methods: AKI was defined as ... [more ▼]

Background: Because Liver Transplantation (LT) using DCD has been shown to be risk factor for Acute Kidney Injury (AKI), we reviewed results at our center. Patients and Methods: AKI was defined as decrease >50% eGFR (CKD- EPI) within 48 h postreperfusion (RIFLE). 106 first LT-only [63 DBD (59%) & 43 DCD (41%)] without pre-existing renal dysfunction (eGFR>60 ml/min/1,73 m2, no renal replacement therapy) were performed from 2012 to 2016. Incidence/ risk factors for AKI were assessed. Data: mean (IQR). Results: Incidence of AKI was 33% (35/106). AKI-patients were more hospitalized before LT [9/16 (56%) vs 26/89 (29%), p < 0.01], with higher labMELD [16 (10–23) vs 12 (8–16), p = 0.01]. Donor type [11/43 DCD (25%) vs 24/63 DBD (39%), p = 0.16], donor hepatectomy time [38 min (26–50) vs 35 (25–42), p = 0.37], cold ischemic time [6 h (4.1–7.6) vs 5.1 (3.4–6.4), p = 0.21], time for anastomosis [44 min (35–49) vs 42 (38–48), p = 0.53], postreperfusion syndrome [19/46 (42%) vs 27/46 (58%), p = 0.07] were similar between AKI & non-AKI groups. AKI was more frequent if lungs were procured first in the donor [23/48 (48%) vs 11/56 (19%), p < 0.01]. Recipient surgery was longer in the AKI group [5.2 h (3.9–6.3) vs 4.3 (3.4–4.8), p < 0.01]. AKI was more frequent if platelets were transfused during LT [19/42 (56%) vs 15/59 (44%), p = 0.03]. Blood volume administrated from the cellsaver was larger in the AKI-patients [834 ml (300–750) vs 408 (0–550), p = 0.03]. AKI-patients have a higher peak AST [1235 U/L (310–1858) vs 812 (429–978), p = 0.04]. Haemoglobin [8.8 g/dl (7.4–9.9) vs 10 (8.5–11.7)] & platelets [69x103 (50 9 103–87 9 103) vs 89 9 103 (50 9 103–118 9 103)] at day 1 postreperfusion were significantly lower if AKI occurred. After multivariable analysis, thoracic procurement before liver [OR 5.75 (1.76–18.77), p = 0.004] & recipient surgery duration [OR 1.64 (1.15–2.32), p = 0.006] were only risk factors for AKI. Conclusion: Rapid donor/recipient surgery and not donor type are key factors to prevent AKI-post-LT. [less ▲]

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See detailImpact of a mountain ultra-marathon (UTMB) on cardiac biomarkers
Le Goff, Caroline ULiege; Gergelé, Laurent; Kaux, Jean-François ULiege et al

in European Journal of Sports Medicine (2017, September), 5(Supplement 1), 15-16

OBJECTIVES: While moderate exercise has beneficial effects on the cardiovascular system, consequences of a supraphysiological effort are not clear yet. In particular, the physiological consequences of ... [more ▼]

OBJECTIVES: While moderate exercise has beneficial effects on the cardiovascular system, consequences of a supraphysiological effort are not clear yet. In particular, the physiological consequences of ultramarathons need to be further documented. The aim of the study was to assess the changes of various cardiac biomarkers after a mountain ultramarathon. MATERIAL AND METHODS: Blood and urine samples were collected on 28 runners (17 men) participating to the UltraTrail du Mont Blanc (105 km, total positive elevation: 5600 m) at 3 different times: before the race (Pre), within 1 h after the finish (Post) and 7 days after the finish (D+7). Several biomarkers involved in heart disease (coronary syndrome, heart failure and fibrosis) and in inflammation were assayed on different analyzers such a COBAS® (for CKMB,TnThs, NTproBNP, HFABP and CRPs) and KRYPTOR® (for Copeptin). ST2 was measured manually with the Presage kit from CRITICAL DIAGNOSTIC®. RESULTS: Plasma levels of cardiac markers (CKMB, TnThs, NTproBNP, copeptin, HFABP, ST2) and inflammation (CRPs) increased significantly at Post. Means values increased from Pre to Post as follows: 2.3 to 91.9 UI/L for CKMB (p<0.0001); 7.6 to 31.7 ng/L for TnThs (p<0.0001); 41.7 to 1190.5 ng/L for NTproBNP, 4.2 to 22.9 pmol/L for copeptin (p=0.001); 3.6 to 107.8 ng/mL for HFABP (p<0.0001), 29.7 to 126.2 ng/mL for ST2 (p<0.0001); 0.5 to 29.1 mg/L for CRPs (p<0.0001). With the exception of a few (HFABP, ST2, CRPs) biomarkers in some subjects, all values were back to Pre values at D+7. DISCUSSION/CONCLUSION: Prolonged strenuous running exercise caused an elevation in cardiac biomarkers. Elevation in CKMB levels lacks specificity for cardiac damage as runners have increased CKMB from skeletal muscles as well. Previous studies suggested that exercise induced TnThs elevation is a benign reversible physiologic phenomenon but this parameter, as well as HFABP, could be a sign of ischemia. Different phenomena occurred such as stretch of myocytes causing an increase in pressure or volume and neurohormonal activation which can explain the Copeptine and NTproBNP increase, while ST2 is a biomarker of cardiac remodeling and fibrosis. CRP is an acute phase compound that tends to increase following a strenuous and prolonged bout of exercise and/or muscular injury. As the values tended to return within the normal reference range values within 7 days after the race, our study suggests that there is no permanent structural damage at the myocardium level. [less ▲]

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See detailisokinetic profile of subjects with proximal patellar tendinopathy
Croisier, Jean-Louis ULiege; Libertiaux, Vincent ULiege; Kaux, Jean-François ULiege

in European Journal of Sports Medicine (2017, September), 5(Supplement 1), 65-66

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See detailValidity and reliability of the French translation of the VISA-A questionnaire
Bruyère, Olivier ULiege; Kaux, Jean-François ULiege; Croisier, Jean-Louis ULiege

in European Journal of Sports Medicine (2017, September), 5(Supplement 1), 64

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See detailPlatelet-rich plasma versus hyaluronic acid to treat tendinopathies
Kaux, Jean-François ULiege; Robertjot, Mathieu; SAMSON, Antoine ULiege et al

in European Journal of Sports Medicine (2017, September), 5(Supplement 1), 21-22

INTRODUCTION: The treatment of patellar tendinopathies could be difficult. This is the reason why new treatments have been developed, among which platelet rich plasma (PRP) injections. Some clinical ... [more ▼]

INTRODUCTION: The treatment of patellar tendinopathies could be difficult. This is the reason why new treatments have been developed, among which platelet rich plasma (PRP) injections. Some clinical series have previously evaluated the effect of PRP in the treatment of proximal patellar tendinopathies. Recent systematic review concluded that PRP could be recommend as a treatment in such indication (1). Recently, the viscoelastic properties of hyaluronic acid (HA) on liquid connective tissue have been proposed for the treatment of tendinopathies (2). Some fundamental studies show encouraging results on HA’s ability to promote tendon gliding and reduce adhesion as well as to improve tendon architectural organisation. Some observations also support its use in a clinical setting to improve pain and function. PURPOSE: We aimed to compare the effect of PRP injection versus two injections of HA after three months on patients who have a proximal patellar tendinopathy. METHODS: Thirtythree sportsmen with proximal patellar tendinopathies being not relieved after minimum three months of normal physiotherapy treatments where included. Eighteen of them (group 1) have received a leukocyte poor PRP injection (obtained using an aphaeresis machine (3)) and the other fifteen (group 2) two HA injections, all of them have benefited of standardized rehabilitation. Concerning the evaluation of the pathology, algofunctional tests (visual analogic scale (VAS), pressure algometer, IKDC score, VISAP score), isokinetic (associated to VAS) along with the patellar tendon ultrasonography (US) have been realized over three times (preinjection, after 6 weeks, after 3 months postinjections). RESULTS: The results of VAS (p<0,01), algometric scores (p<0,01), IKDC scores (p<0,01) and VISAP (p<0,01) show a considerable improvement in the two groups, but not for the US findings. For the group 1, isokinetic tests show significative results for the hamstrings in C60°/s with an improvement of maximum peak torque (p=0,01) for the pathological member, a diminution (p>0,05) for the healthy limb and during the analysis of the bilateral difference (p=0,0002). For the group 2, the improvement of quadriceps maximum peak torque in C240°/s is significant (p>0,01) for the pathological knee after 6 weeks post injections only. The VAS associated with isokinetic tests decreases significantly for all contraction modes after three months of study. CONCLUSIONS: Both PRP and HA can improve the symptoms of proximal patellar tendinopathy, even if the results are slightly better in the PRP group. REFERENCES: Andia I et al., Plateletrich plasma in the conservative treatment of painful tendinopathy: a systematic review and metaanalysis of controlled studies. Br Med Bull. 2014 Jun;110(1):99115. Kaux JF et al., Hyaluronic acid and tendon lesions. Muscles Ligaments Tendons J. 2016 Feb 13;5(4):2649. Kaux JF et al. Using platelet rich plasma to treat jumper's knees: Exploring the effect of a second closely timed infiltration. J Sci Med Sport. 2016 Mar;19(3):2004. [less ▲]

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See detailEnhancing CIDOC - CRM and compatible models with the concept of multiple interpretation
Van Ruymbeke, Muriel ULiege; Hallot, Pierre ULiege; Billen, Roland ULiege

in ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences (2017, August 17), Volume IV-2/W2

Modelling cultural heritage and archaeological objects is used as much for management as for research purposes. To ensure the sustainable benefit of digital data, models benefit from taking the data ... [more ▼]

Modelling cultural heritage and archaeological objects is used as much for management as for research purposes. To ensure the sustainable benefit of digital data, models benefit from taking the data specificities of historical and archaeological domains into account. Starting from a conceptual model tailored to storing these specificities, we present, in this paper, an extended mapping to CIDOC-CRM and its compatible models. Offering an ideal framework to structure and highlight the best modelling practices, these ontologies are essentially dedicated to storing semantic data which provides information about cultural heritage objects. Based on this standard, our proposal focuses on multiple interpretation and sequential reality. [less ▲]

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See detailPOINT CLOUD CLASSIFICATION OF TESSERAE FROM TERRESTRIAL LASER DATA COMBINED WITH DENSE IMAGE MATCHING FOR ARCHAEOLOGICAL INFORMATION EXTRACTION
Poux, Florent ULiege; Neuville, Romain ULiege; Hallot, Pierre ULiege et al

in ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences (2017, August 16), IV-2/W2

Reasoning from information extraction given by point cloud data mining allows contextual adaptation and fast decision making. However, to achieve this perceptive level, a point cloud must be semantically ... [more ▼]

Reasoning from information extraction given by point cloud data mining allows contextual adaptation and fast decision making. However, to achieve this perceptive level, a point cloud must be semantically rich, retaining relevant information for the end user. This paper presents an automatic knowledge-based method for pre-processing multi-sensory data and classifying a hybrid point cloud from both terrestrial laser scanning and dense image matching. Using 18 features including sensor’s biased data, each tessera in the high-density point cloud from the 3D captured complex mosaics of Germigny-des-prés (France) is segmented via a colour multi-scale abstraction-based featuring extracting connectivity. A 2D surface and outline polygon of each tessera is generated by a RANSAC plane extraction and convex hull fitting. Knowledge is then used to classify every tesserae based on their size, surface, shape, material properties and their neighbour’s class. The detection and semantic enrichment method shows promising results of 94% correct semantization, a first step toward the creation of an archaeological smart point cloud. [less ▲]

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See detailAn efficient algorithm to decide periodicity of b-recognisable sets using MSDF convention
Boigelot, Bernard ULiege; Mainz, Isabelle ULiege; Marsault, Victor ULiege et al

in Leibniz International Proceedings in Informatics (2017, August), 80

Given an integer base b>1, a set of integers is represented in base b by a language over {0,1,...,b-1}. The set is said to be b-recognisable if its representation is a regular language. It is known that ... [more ▼]

Given an integer base b>1, a set of integers is represented in base b by a language over {0,1,...,b-1}. The set is said to be b-recognisable if its representation is a regular language. It is known that eventually periodic sets are b-recognisable in every base b, and Cobham's theorem implies the converse: no other set is b-recognisable in every base b. We are interested in deciding whether a $b$-recognisable set of integers (given as a finite automaton) is eventually periodic. Honkala showed that this problem is decidable in 1986 and recent developments give efficient decision algorithms. However, they only work when the integers are written with the least significant digit first. In this work, we consider the natural order of digits (Most Significant Digit First) and give a quasi-linear algorithm to solve the problem in this case. [less ▲]

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See detailMonitoring of comets activity and composition with the TRAPPIST-North telescope
Moulane, Youssef ULiege; Benkhaldoun, Zouhair; Jehin, Emmanuel ULiege et al

in Journal of Physics: Conference Series (2017, July), 869

TRAPPIST-North (TRAnsiting Planets and PlanetesImals Small Telescope) is a 60-cm robotic telescope that was installed in May 2016 at the Oukaimeden Observatory. The project is led by the University of ... [more ▼]

TRAPPIST-North (TRAnsiting Planets and PlanetesImals Small Telescope) is a 60-cm robotic telescope that was installed in May 2016 at the Oukaimeden Observatory. The project is led by the University of Liège (Belgium) and the Caddi Ayad University of Marrakech (Morocco). This telescope is a twin of the TRAPPIST-South telescope, which was installed at the ESO La Silla Observatory in 2010. The TRAPPIST telescopes are dedicated to the detection and characterization of planets orbiting stars other than our Sun (exoplanets) and the study of comets and other small bodies in our solar system. For the comets research, these telescopes have very sensitive CCD cameras with complete sets of narrow band filters to measure the production rates of several gases (OH, NH, CN, C3 and C2) and the dust. With TRAPPIST-North we can also observe comets that would not be visible in the southern hemisphere. Therfore, with these two telescopes, we can now observe continuously the comets around their orbit. We project to study individually the evolution of the activity, chemical composition, dust properties, and coma morphology of several comets per year and of different origins (New comets and Jupiter Family comets) over a wide range of heliocentric distances, and on both sides of perihelion. We measure the production rates of each daughter molecules using a Haser model, in addition to the Afρ parameter to estimate the dust production in the coma. In this work, we present the first measurements of the production rates of comet C/2013 X1 (PANSTARRS) observed with TN in June 2016, and the measurements of comet C/2013 V5 (Oukaimeden) observed in 2014 with TRAPPIST-South. [less ▲]

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See detailTrajectory planning of soft link robots with improved intrinsic safety
Lismonde, Arthur ULiege; Sonneville, Valentin; Bruls, Olivier ULiege

in IFAC-PapersOnLine (2017, July)

For human-robot cooperation, intrinsic safety approaches aim at reducing the energy involved in the motion of the robotic system and at increasing the system compliance in order to reduce the risk of ... [more ▼]

For human-robot cooperation, intrinsic safety approaches aim at reducing the energy involved in the motion of the robotic system and at increasing the system compliance in order to reduce the risk of injury in case of an unexpected collision. Robots based on lightweight and inherently exible links exhibit attractive features in this context but the control of their motion then leads to a tremendous challenge. This paper presents a novel trajectory planning method for 3D robots which aims at improving the tracking accuracy despite the link exibility. [less ▲]

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See detailVibration Induced Phenomena in Granular Media in Microgravity
Opsomer, Eric ULiege; Noirhomme, Martial ULiege; Vandewalle, Nicolas ULiege

in EPJ Web of Conferences (2017, June 30)

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See detailSmall solar system bodies as granular systems
Hestroffer, Daniel; Campo Bagatin, Adriano; Losert, Wolfgang et al

in EPJ Web of Conferences (2017, June 30)

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See detailDeformation measurements by ESPI of the surface of a heated mirror and comparison with numerical model
Languy, Fabian ULiege; Vandenrijt, Jean-François ULiege; Saint-Georges, Philippe et al

in Proceedings of SPIE (2017, June 26), 103291M

The manufacture of mirrors for space application is expensive and the requirements on the optical performance increase over years. To achieve higher performance, larger mirrors are manufactured but the ... [more ▼]

The manufacture of mirrors for space application is expensive and the requirements on the optical performance increase over years. To achieve higher performance, larger mirrors are manufactured but the larger the mirror the higher the sensitivity to temperature variation and therefore the higher the degradation of optical performances. To avoid the use of an expensive thermal regulation, we need to develop tools able to predict how optics behaves with thermal constraints. This paper presents the comparison between experimental surface mirror deformation and theoretical results from a multiphysics model. The local displacements of the mirror surface have been measured with the use of electronic speckle pattern interferometry (ESPI) and the deformation itself has been calculated by subtracting the rigid body motion. After validation of the mechanical model, experimental and numerical wave front errors are compared. [less ▲]

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See detailLeibniz and the Polyp, or the Metaphysical Puzzle of Life
Dony, Arthur ULiege

in Scienza e Philosophia (2017, June), 17

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See detailEstablishment of reference values for 6 six steroids in serum
LE GOFF, Caroline ULiege; Fabregat Cabello, Neus ULiege; Huyghebaert, Loreen ULiege et al

in Clinical Chemistry and Laboratory Medicine (2017, June)

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See detailQuantification of serum androstanediol glucuronide
LE GOFF, Caroline ULiege

in Clinical Chemistry and Laboratory Medicine (2017, June)

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See detailEmpathie et culpabilité : les émotions au coeur du lien social
Devillers, Bérengère ULiege

in Actes des 17èmes journées de valorisation de la recherche « La place des émotions dans le travail socio-éducatif » (2017, June)

Bonjour à tous, et merci aux organisateurs de m’avoir invitée. C’est un plaisir pour moi d’être là aujourd’hui parmi vous. Je vais tout d’abord revenir sur la traduction du « Good Lives Model ». Plusieurs ... [more ▼]

Bonjour à tous, et merci aux organisateurs de m’avoir invitée. C’est un plaisir pour moi d’être là aujourd’hui parmi vous. Je vais tout d’abord revenir sur la traduction du « Good Lives Model ». Plusieurs traductions sont communément admises, les plus connues étant celles de « modèle de bonne vie » ou « modèle de vie satisfaisante » ou encore « modèle de vies saines ». Il faut savoir que le groupe Antigone, dans lequel je travaille, n’adhère pas vraiment à ces définitions. En effet, nous trouvons que les traductions françaises proposées enferment le sujet dans une vision prescriptive de ce que devraient être les besoins, qu’elles laissent entendre qu’il y aurait des besoins universels auxquels tous les individus devraient répondre. Or nous ne nous y retrouvons pas et cela ne correspond pas à l’intention de Ward qui veut faire référence à une manière de vivre qui est bénéfique pour le sujet lui-même. Je vous propose donc de garder l’appellation anglophone, « Good Lives Model ». Je vais revenir à l’émergence de ce modèle : il s’agit d’un modèle de réhabilitation qui a vu le jour au début des années 2000 sous l’impulsion de Tony Ward, tout d’abord pour le public des auteurs d’infractions à caractère sexuel. Cependant, il s’est rapidement étendu à d’autres populations, notamment les auteurs de violences domestiques, le public psychiatrique, et ce pour le public aussi bien adolescent qu’adulte. D’autres adaptations ont depuis vu le jour, notamment à l’initiative d’un service français, l’ARCA, qui est spécialisé en recherche et en intervention en délinquance sexuelle, et où le directeur, Erwan Dieu, a adapté le Good Lives Model au public radicalisé. Plusieurs expériences ont également été menées en Belgique, notamment une à l’hôpital des Marronniers, à Tournai, dans une unité de défense sociale qui accueille des délinquants sexuels. L’équipe a décidé, suite à une formation, de reprendre les outils du Good Lives Model et de les adapter avec les patients, afin qu’ils correspondent à leur langage, à leur niveau de compréhension et donc à leurs besoins. Le GLM se veut avant tout humaniste, positiviste et tout à fait écologiste, parce qu’il tient compte des différents systèmes qui gravitent autour de la personne. Il a pour première cible de traitement le développement des besoins humains fondamentaux. Sa deuxième cible est la réduction du risque de récidive, mais qui se veut être un effet de la poursuite du bien-être et des besoins des personnes. Le Good Lives Model comprend des principes théoriques et des implications cliniques. Selon un principe prioritaire au niveau théorique, nous considérons que le délinquant est animé par les mêmes besoins humains que tout un chacun, mais que les voies qu’il emprunte ne sont pas pro-sociales. Nous mettrons donc la notion de besoin au centre de la prise en charge, bien plus que le passage à l’acte délinquant. Le principe clinique qui me paraît être le plus en lien avec le thème qui nous occupe aujourd’hui est peut-être la notion de responsabilité à substituer à celle de culpabilité. Je ne connais pas précisément votre cadre légal protectionnel de la jeunesse. En Belgique, dans les mesures qui sont privilégiées par le magistrat de la jeunesse dès lors qu’un jeune a commis un fait qualifié d’infraction, nous retrouvons les mesures réparatrices, mais dans une visée de responsabilisation du jeune, de prise en compte des conséquences dommageables pour les victimes. Tel est le mandat qui est confié aux équipes chargées du suivi du jeune. Dans le cadre de la philosophie du modèle GLM, nous verrons s’opérer un glissement de la notion de responsabilité, qui reposait avant tout sur les épaules du jeune, vers celles de l’intervenant psychosocial et de son environnement proche : les familiers, mais aussi tous les intervenants gravitant autour du jeune. Par quoi cela passe-t-il concrètement ? Tout d’abord le GLM est attentif à la définition du problème. Bien souvent, le problème est libellé soit dans les rapports qui ont été rédigés par au sujet du jeune, soit dans l’ordonnance qui précise notamment la qualification des faits. Nous laisserons cela de côté, et nous repartirons avec le jeune de la définition du problème tel qu’elle se pose pour lui, dans l’ici et maintenant. Nous ne repartirons donc pas du passé, mais nous nous centrerons sur les conséquences pour lui et pour son environnement dans le présent, ce qui suppose que nous devrons nous accorder sur les buts et objectifs de la prise en charge. Le jeune et les intervenants seront donc associés aux différentes phases du plan de traitement, où les intervenants psychosociaux auront également une responsabilité. Par conséquent, ils s’engageront à réaliser des démarches avec le jeune. Par quoi passe encore cette responsabilité ? L’intervenant psychosocial devra créer les conditions propices à un engagement et à un maintien du jeune dans la prise en charge. La notion de disposition au traitement (Treatment Readiness, Ward et al., 2004) nous éclaire ici sur cette question de l’engagement tant de l’usager que de l’intervenant dans le processus de changement. En effet, la disposition au traitement est définie comme étant « la présence de caractéristiques (états et dispositions) dans le chef du délinquant mais aussi de la situation thérapeutique qui sont susceptibles de promouvoir l’engagement dans la thérapie et donc l’amélioration des aptitudes au changement thérapeutique » (Ward et al., 2004). Il existe également un langage assez particulier qui devra être adapté aux besoins et au niveau de développement du jeune. Tony Ward avait initialement énoncé onze besoins fondamentaux, et le GMAP, qui est le service en Nouvelle-Zélande ayant adapté le GLM pour les adolescents, a réduit le nombre de besoins à huit. Les besoins couvriront surtout la santé (émotionnelle, en général et sexuelle) ainsi que les besoins de réalisation, d’amusement, de trouver un sens à sa vie et de développer des relations. Nous travaillerons donc beaucoup tout ce qui est du registre des émotions, soit tout d’abord pouvoir identifier ses émotions avant de pouvoir les gérer. Dans les questions en lien avec le modèle de réhabilitation, il est vrai que nous travaillons le lien social. Or, dans l’optique GLM, nous ferons d’abord passer le lien social par un lien à restaurer du jeune vis-à-vis de lui-même. Dans l’optique GLM, nous considérerons que travailler le lien social et la réparation d’un dommage vis-à-vis de la société sans se soucier d’abord d’une réparation à l’encontre du jeune est anticipé, par rapport au fait de vouloir d’emblée se lancer dans une logique de réparation. Par conséquent, un accent est mis sur une alliance thérapeutique, et le jeune se sentira beaucoup plus concerné puisque nous partirons de sa définition à lui du problème, telle qu’elle se pose pour lui avant tout. Il pourra alors retrouver un sens, et quelque part, sortir un peu de cette stigmatisation, de cet étiquetage qui lui pèse et qui est souvent lié à tout son parcours, ou qui transparaît au travers des différents rapports, des diverses rencontres avec le magistrat ou les intervenants. Cette optique de travail pourra permettre également au jeune de sortir de ses mécanismes de défense, de faciliter une distanciation par rapport aux mécanismes habituels de minimisation, de déni, d’opposition, et nous verrons que les équipes ou les intervenants qui s’imprègnent de principes liés au GLM pourront s’inscrire davantage dans des rapports relationnels s’éloignant de rapports d’opposition, de recadrage (tels que souvent vécus par les équipes). Pour revenir sur l’expérience menée aux Marronniers, il a été constaté, dans les effets au premier plan, une amélioration de la qualité relationnelle avec les patients. Ceux-ci étaient tout à fait étonnés que l’équipe se détache du travail centré exclusivement sur les passages à l’acte, la récidive, les perspectives de réhabilitation, pour s’intéresser à leurs besoins. Le deuxième effet observé concerne le bien-être des travailleurs, qui s’est traduit par une réduction significative du taux d’absentéisme. L’équipe psycho-sociale ressentant en effet davantage de plaisir à travailler les forces plutôt que les déficits de leurs patients. Avec le jeune, nous travaillons aussi la question de la responsabilité active : toujours dans la notion d’ici et maintenant, que pourra engager le jeune, par exemple si un membre de la famille est toujours très préoccupé, s’il s’agit d’un abus intrafamilial, par la réalité du risque au quotidien ? Que peut dire le jeune de son rapport à la sexualité, mais vraiment dans l’ici et maintenant et dans des perspectives futures, dans ce qu’il peut mettre en place pour rassurer sa famille ? Nous travaillons donc le projet du jeune centré sur ses besoins et son avenir, et beaucoup moins le passé. Cela ne veut pas dire qu’il n’y a pas de place pour le travail sur l’empathie, sur les habilités relationnelles, personnelles et sociales, mais nous nous recentrons d’abord sur le jeune, sur les situations d’adversité qu’il a pu rencontrer durant sa trajectoire de vie afin de favoriser une expression libre de ses émotions. Comme nous l’avons vu avec notre collègue Nadine Lanctôt, bien souvent, nous pointons du doigt tous les éléments de victimisation, maltraitance sexuelle, négligence, mais nous oublions tout l’effet des violences plus émotionnelles, plus insidieuses, qui ont également des effets tout à fait délétères sur le développement du jeune. Ainsi, nous trouvons important de travailler toute cette reconnexion du jeune à ses différents états émotionnels, afin qu’il puisse distinguer le registre des idées, des émotions, des sensations physiologiques, pour ensuite pouvoir refaire ce travail vis-à-vis du passage à l’acte. Le GLM offre un cadre conceptuel et opérationnel utile aux professionnels pour intégrer une gamme d’évaluations et d’informations, de supports théoriques et d’outils d’intervention, dans la perspective d’une compréhension riche, cohérente et complémentaire des (et avec leurs) usagers. [less ▲]

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See detailImpact of an ultra-trail of 330 km on plasma levels
LE GOFF, Caroline ULiege; Kaux, Jean-François ULiege; Gergelé, Laurent et al

in Clinical Chemistry and laboratory medicine (2017, June)

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See detailComparison of cardiac biomarker fluctuation in runners of marathons, semi-marathons and untrained runners
LE GOFF, Caroline ULiege; VRANKEN, Laura ULiege; van Nueten, Jan et al

in Clinical Chemistry & Laboratory Medicine (2017, June)

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See detailReference interval determination for serum and urine aldosterone for healthy Belgian population
LE GOFF, Caroline ULiege; Fabregat Cabello, Neus ULiege; Huyghebaert, Loreen ULiege et al

in Clinical Chemistry & Laboratory Medicine (2017, June)

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See detailNondestructive inspection of aerospace composites by a fiber-coupled laser ultrasonics system
Vandenrijt, Jean-François ULiege; Languy, Fabian ULiege; Thizy, Cédric ULiege et al

in Proceedings of SPIE (2017, June)

Laser ultrasonics is a technique currently studied for nondestructive inspection of aerospace composite structures based on carbon fibers. It combines a pulsed laser impacting the surface generates an ... [more ▼]

Laser ultrasonics is a technique currently studied for nondestructive inspection of aerospace composite structures based on carbon fibers. It combines a pulsed laser impacting the surface generates an ultrasound inside the material, through the nondestructive thermoelastic effect. Second a detection interferometer probes the impacted point in order to measure the displacement of the surface resulting from the emitted ultrasound wave and the echo coming back from the different interfaces of the structure. Laser ultrasonics is of interest for inspecting complex shaped composites. We have studied the possibility of using frequency doubled YAG laser for the generation and which is fiber-coupled, together with a fiber-coupled interferometric probe using a YAG laser in the NIR. Our final system is a lightweight probe attached to a robot arm and which is able to scan complex shapes. The performances of the system are compared for different wavelengths of generations. Also we have studied some experimental parameters of interest such as tolerance to angle and focus distance, and different geometries of generation beams. We show some examples of inspection of reference parts with known defects. In particular C-scans of curved composites structures are presented. [less ▲]

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See detailNGOs and female circumcision in Egypt. An anthropological enquiry
Mescoli, Elsa ULiege

in The Journal of the Anthropology of the Contemporary Middle East and Central Eurasia (2017, June)

In 1994, during the International Conference on Population and Development convened by the United Nations in Cairo, a shocking video was shown, realized by an operator of CNN and depicting the ... [more ▼]

In 1994, during the International Conference on Population and Development convened by the United Nations in Cairo, a shocking video was shown, realized by an operator of CNN and depicting the circumcision of a ten-year-old child living in this very same city. Discourses around female circumcision were not new in Egypt and in the international community, but what was considered as a new episode of a recurrent scandal (not the last one indeed) led to enhance the “war against bad government” (Foucault 2003: 38). A war fought by means of ideological weapons produced by various forms of expert knowledge among which the medical and the feminist ones. The assignment of a value to the state of integrity of the female body and to the women freedom of choice, both designed according to Western canons, led to different actions to “save” Egyptian women. In this context, development agencies foster a widespread representation of the victim, constituted by the woman mutilated body. Such representation is functional to put in place programs which do not guarantee a freedom of choice, but rather require adherence to another female model, one that defines the "modern" woman. My article, based on ethnographic experience, aims at highlighting the complexity of such dynamics and the role played by humanitarianism within them. Female body becomes the arena where local and international economic powers operate, disregarding a real understanding of the practice, its meanings and its eventual change. [less ▲]

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See detailChanges in preoptic estradiol concentrations during male sexual behavior
de Bournonville, Marie-Pierre ULiege; de Bournonville, Catherine; Ball, Gregory et al

in Frontiers in Neuroscience (2017, May 30)

Besides its long-term control by steroids, male sexual behavior is also modulated by membrane-initiated effects of neuroestrogens in the short-term (within minutes). These effects are thought to depend on ... [more ▼]

Besides its long-term control by steroids, male sexual behavior is also modulated by membrane-initiated effects of neuroestrogens in the short-term (within minutes). These effects are thought to depend on short-term variations in the local production of estrogens, through rapid fluctuations of the enzymatic activity of brain aromatase, the enzyme that synthesizes estradiol (E2) from testosterone. Studies in male Japanese quail have shown that a sexual interaction with a female leads to a decrease in the activity of brain aromatase within minutes. These effects occur mainly within the medial preoptic nucleus (POM), a sexually dimorphic structure of the preoptic area that plays a key role in the activation of male sexual behavior and contains the highest aromatase activity (AA) in the brain. However recent studies showed that AA does not always reflect local E2 concentration. For example, while an acute stress decreases AA in the POM, E2 concentration increases in the same conditions. Here we used in vivo microdialysis to quantify changes in E2 concentration in the male POM during sexual interactions with a female. A series of experiments conducted to validate the in vivo dialysis and RIA methods showed that (1) E2 concentration in the dialysate change linearly with the concentration of a bath containing known amounts of E2 in which the probe was placed, (2) an increase in preoptic E2 concentration is observed after retrodialysis of testosterone and (3) preoptic E2 levels also increase after a peripheral injection of E2. Together these results suggest that in vivo dialysis is a suitable method to assay E2 in the range of brain concentrations suspected to be present in physiological conditions. With this approach, we showed during two independent experiments that E2 concentrations increase in the POM during sexual interactions with a female. Birds that had their cannula placed outside the POM did not show any increase in E2 levels. The E2 increase in the POM could serve to maintain motivation during the entire sexual encounter. The decrease of AA observed ex vivo after copulation would then reflect a compensatory mechanism to restore baseline pre-copulatory conditions. [less ▲]

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See detailNumerical analysis and design optimization of multi-coil units for latent heat cold storage applications
Hastanin, Juriy ULiege; Salvador, Lucas ULiege

in International Conference on Environment and Renewable Energy (2017, May 04)

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See detailMODELISATION D’UN ECHANGEUR A THERMOSIPHONS POUR LA RECUPERATION DE CHALEUR
Le, Van Long ULiege; Dumas, Xavier; Ferrand, Ludovic et al

in XIIIème Colloque Interuniversitaire Franco-Québécois sur la Thermique des Systèmes (2017, May)

Le présent travail a pour objectif de modéliser un échangeur à thermosiphons diphasiques pour transporter la chaleur d’un effluent gazeux (c.à.d. gaz de combustion) à haute température (720°C) au système ... [more ▼]

Le présent travail a pour objectif de modéliser un échangeur à thermosiphons diphasiques pour transporter la chaleur d’un effluent gazeux (c.à.d. gaz de combustion) à haute température (720°C) au système ORC (cycle organique de Rankine). Les thermosiphons sont placés dans les gaz de combustion et refroidis par le fluide de travail du système ORC (le Cyclopentane pour le cas actuel). Le débit massique des fumées et la puissance thermique de l’échangeur sont respectivement imposés de 21 kg/s et de 4.022 MWth. Le fluide organique s’évapore à une température de 200°C et quitte l’évaporateur sans surchauffe (vapeur saturée). Le modèle de simulation développé dans le logiciel EES (Engineering Equation Solver) est capable de déterminer le nombre nécessaiare de thermosiphons. L’influence des pas transversaux et longitudinaux de l’échangeur sur le nombre de thermosiphons et la perte de charge des fumées est également examinée pour les dispositions quinconces et alignées des tubes de thermosiphons. [less ▲]

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See detailCanopy aerodynamic distance (z-d) estimation and impact on eddy covariance measurements
Hurdebise, Quentin ULiege; De Ligne, Anne ULiege; Vincke, Caroline et al

in Geophysical Research Abstracts 2017 (2017, April 24)

Understanding if and how the spatial and temporal variability of the surrounding environment affects turbulence is essential for long-term eddy covariance measurements above growing and heterogeneous ... [more ▼]

Understanding if and how the spatial and temporal variability of the surrounding environment affects turbulence is essential for long-term eddy covariance measurements above growing and heterogeneous ecosystems. It requires characterizing the surrounding environment. One way to achieve this is to analyse the canopy aerodynamic distance, which is the difference between measurement height (z) and displacement height (d). In this study, twenty years of eddy covariance measurements from the Vielsalm Terrestrial Observatory, a site located in a mixed temperate forest, were used. Canopy aerodynamic distance (z-d) estimates were obtained using two micrometeorological methods: the first one, which is original so far as we know, was based on analysing sensible heat cospectra; the second one was derived from the wind speed profile equation. Canopy height estimates based on inventories were used to validate both methods. The micrometeorological methods allowed the z-d variations due to changes in canopy or measurement height to be detected. In addition, the results obtained using the two methods were well correlated, spatially and temporally, with the z-d derived from canopy height measurements. The micrometeorological approaches used could therefore be a promising tool for investigating z-d variability at a high directional and temporal resolution. Questions remain, however, particularly with regard to the variability observed that cannot be explained by canopy or measurement height variation. Forest management practices and the non-fulfilment of similarity relationships were suspected to be the main explanatory factors. [less ▲]

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See detailThe Belgian Internment Policy as an Example of Hybrid Governance
Pans, Maurice; Darcis, Coralie ULiege

in Tijdschrift voor Bestuurswetenschappen en Publiekrecht (2017, April), 4(4),

Het domein van de zorg voor geïnterneerde personen kent internationaal een omslag. Naast de “criminalisering” van personen met een psychiatrische stoornis die criminele feiten begaan, ontwikkelen er zich ... [more ▼]

Het domein van de zorg voor geïnterneerde personen kent internationaal een omslag. Naast de “criminalisering” van personen met een psychiatrische stoornis die criminele feiten begaan, ontwikkelen er zich nieuwe visies en zorgperspectieven op de kwaliteit van leven en de re-integratie in de maatschappij van zowel personen met psychische kwetsbaarheid als geïnterneerde personen.1 Tot zeer recent werden geïnterneerde personen bijna exclusief benaderd als personen die misdaden of misdrijven hebben gepleegd waar ze door hun psychische stoornis niet voor verantwoordelijk konden worden gesteld. De onderliggende logica van de aanpak was sterk geënt op een model waarbij opsluiting en isolatie van de maatschappij centraal stonden omwille van misdaad. Geïnterneerde personen werden om die reden opgesloten in een gevangenissysteem volgens een justitiële benadering. Het behandelings- en zorgperspectief raakte hierbij ondergesneeuwd. De “criminalisering” van personen met psychische stoornissen heeft in België historisch geleid tot inadequate aanpak en begeleiding van deze groep patiënten. Meerdere veroordelingen van de Belgische Staat door het Europees Hof voor de Rechten van de Mens (EHRM), overvolle gevangenissen, het gebrek aan somatische en psychiatrische gezondheidszorg binnen gevangenissen en psychiatrische annexen en aanbevelingen van het Europees Comité voor de Preventie van Foltering en Onmenselijke of Vernederende Behandeling of Bestraffing (CPT) zijn directe aanleidingen voor het Masterplan Internering (juni 2016)2 en de wet van 5 mei 2014 betreffende de internering van personen3. In deze bijdrage staan we stil bij het Masterplan Internering van 2016 en de nieuwe Interneringswet van 5 mei 2014. We proberen te duiden op welke manier in beide bronnen randvoorwaarden worden gecreëerd voor een hybride bestuursvorm in de sector. We staan kort stil bij beleidsmatige en juridische ontwikkelingen die vooraf gingen. [less ▲]

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See detailAn innovative non-animal chitosan hydrogel is able to restore the rheology of osteoarthritis synovial fluid ex vivo
Henrotin, Yves ULiege; Rocasalbas, Guillem; Chausson, Mickaël et al

in Osteoarthritis and Cartilage (2017, April)

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See detailTraduction en français du "back pain attitudes questionnaire" et étude de ses qualités métrologiques
Demoulin, Christophe ULiege; hALLEUX, V.; DARLOW, B. et al

in Kinesitherapie Revue (2017, April), 184

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See detailÉtude du degré de satisfaction de patients lombalgiques au sujet de la brochure éducative « PAIN fundamentals »
Demoulin, Christophe ULiege; Blanc, A.; Wolfs, Sébastien ULiege et al

in Kinesitherapie Revue (2017, April), 184

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See detailContrôle du mouvement lombopelvien et football
Grosdent, Stéphanie ULiege; Demoulin, Christophe ULiege; Cortès Flores, A. et al

in Kinesitherapie Revue (2017, April), 184

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See detailStudy of the evolution of the osteoarthritis pathology and the mechanical properties of cartilage in a spontaneous osteoarthritis model in the Dunkin-Hartley guinea pigs.
Legrand, Catherine ULiege; Centonze, Prescilia ULiege; Comblain, Fanny ULiege et al

in Osteoarthritis and Cartilage (2017, April), 25

In animal models, the severity of cartilage damage is assessed by histological scores evaluating the structure, the proteoglycan con- tent, the integrity of the tidemark, the cellularity, and osteophytes ... [more ▼]

In animal models, the severity of cartilage damage is assessed by histological scores evaluating the structure, the proteoglycan con- tent, the integrity of the tidemark, the cellularity, and osteophytes. In parallel to these histological analyzes, we studied the mechanical properties of cartilage at different stages of disease progression in the Dunkin-Hartley guinea pigs. We also correlated the severity of histo- logical lesions with the mechanical properties of cartilage. [less ▲]

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See detailA Markov Chain Monte Carlo Cellular Automata Model to Simulate Urban Growth
El Saeid Mustafa, Ahmed Mohamed ULiege; Nishida, Gen; Saadi, Ismaïl ULiege et al

in GEOProcessing 2017 proceedings, The Ninth International Conference on Advanced Geographic Information Systems, Applications, and Services (2017, March 25)

This paper investigates the potential of a cellular automata (CA) model based on logistic regression (logit) and Markov Chain Monte Carlo (MCMC) to simulate the dynamics of urban growth. The model ... [more ▼]

This paper investigates the potential of a cellular automata (CA) model based on logistic regression (logit) and Markov Chain Monte Carlo (MCMC) to simulate the dynamics of urban growth. The model assesses urbanization likelihood based on (i) a set of urban development driving forces (calibrated based on logit) and (ii) the land-use of neighboring cells (calibrated based on MCMC). An innovative feature of this CA model is the incorporation of MCMC to automatically calibrate the CA neighborhood transition rules. The MCMC based CA model is applied to Wallonia region (Belgium) to simulate urban growth from 1990 to 2000 using Corine Land Cover data (CLC). The outcome of logit model is evaluated by the relative operating characteristic (ROC). The simulated map of 2000 is then validated against 2000 actual map based on cell-to-cell location agreement. The model outcomes are realistic and relatively accurate confirming the effectiveness of the proposed MCMC-CA approach. [less ▲]

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See detailImmunomodulatory effects of rapamycin in xenogeneic Graft versus Host Disease
Ehx, Grégory ULiege; Hannon, Muriel ULiege; DUBOIS, Sophie ULiege et al

in Biology of Blood and Marrow Transplantation (2017, March), 23(3), 365366

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Several studies have suggested that rapamycin (RAPA), an mTOR ... [more ▼]

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Several studies have suggested that rapamycin (RAPA), an mTOR inhibitor with immunosuppressive properties, may reduce GVHD severity and mortality, possibly by promoting regulatory T cells (Tregs). However, few data have been reported about the impact of this drug on overall T cell population. The present work aims at investigating the mechanisms by which RAPA impacts GVHD in a humanized mouse model of GVHD (NSG mice infused with human PBMCs). We observed that RAPA injections significantly reduced xenogeneic GVHD lethality and severity. RAPA dramatically reduced human cells chimerism in RAPA mice and increased CD4+/CD8+ T cells balance due to a lower proliferation of CD8+ T cells. In addition, the frequencies of naive CD4+ and CD8+ T cells were higher and the CD4+ T cells showed a reduced effector phenotype (CD45RO+CD27-). Further, the differentiation of helper T cells (Th1, Th2 and Th17) was significantly decreased in treated mice. Tregs were positively affected as RAPA up-regulated their expression of BCL-2 and KI67 as well as their STAT5 phosphorylation level, leading to higher Treg frequency in treated mice. Altogether these data suggest that RAPA ameliorates GVHD by lowering cytotoxic and effector CD4+ T cells frequency as well as promoting Tregs. [less ▲]

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See detailOsteoarthritis increases the risk of cardiovascular disease: data from the osteoarthritis initiative.
Veronese, N.; Smith, T; Reginster, Jean-Yves ULiege et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailMetronomic treatments in Pediatric Neuro-Oncology, a new therapeutic alternative?
Fohn, Anaïs; Hoyoux, Claire; DRESSE, Marie-Françoise ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2017, March), 19(1), 88

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See detailSarcopenia in nursing home residents: the senior cohort.
Buckinx, Fanny ULiege; Reginster, Jean-Yves ULiege; Beaudart, Charlotte ULiege et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailLow bone mineral density and fractures are associated with incident cardiovascular disease: a systematic review and meta-analysis.
Veronese, N.; Stubbs, B.; Crepaldi, G. et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailThe relationship between knee osteoarthritis and incident hypertension: a representative longitudinal study.
Veronese, N.; Stubbs, B.; Smith, T. et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailPublic health and economic impact of vitamin D-fortified dairy products for fracture prevention in France.
Hiligsmann, M.; Burlet, N.; Fardellone, P. et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailBone quality assessment among sarcopenic and non sarcopenic elderly subjects from the SarcoPhAge Study.
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Delandsheere, Laura ULiege et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailThe SarcoPhAge study: evolution of sarcopenic subjects after 2 years of follow-up.
Beaudart, Charlotte ULiege; Locquet, Médéa ULiege; Reginster, Jean-Yves ULiege et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailPrevalence of sarcopenia accoring to 10 different operational definitions of the frailty.
Buckinx, Fanny ULiege; Reginster, Jean-Yves ULiege; Beaudart, Charlotte ULiege et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailSubjective sleep quality in sarcopenic vs non-sarcopenic older adults from the sarcophage cohort.
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Delandsheere, Laura ULiege et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailProfile of osteoarthritic patients undergoing total hip and knee arthroplasty.
Neuprez, Audrey ULiege; KURTH, William ULiege; GILLET, Philippe ULiege et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailBiomarkers of osteoarthritis : practical considerations.
CAVALIER, Etienne ULiege; Reginster, Jean-Yves ULiege

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailThe risk of subsequent osteoporotic fractures is decreased in patients experiencing fracture while on denosumab: results from the FREEDOM and FREEDOM Extension studies.
Kendler, D.L.; Chines, A.; Brandi, M.L. et al

in Osteoporosis International (2017, March), 28 Suppl 1

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See detailDaily management of knee osteoarthritis: from the ESCEO algorithm to the CONCEPT study.
Reginster, Jean-Yves ULiege

in Osteoporosis International (2017, March), 28 Suppl 1

Detailed reference viewed: 41 (3 ULiège)