References of "Unpublished conference"
     in
Bookmark and Share    
Peer Reviewed
See detailHandling range ambiguities in registration-based range-dependence compensation for conformal array STAP
Ries, Philippe; Verly, Jacques ULg; Lapierre, Fabian D.

Conference (2009)

Detailed reference viewed: 5 (0 ULg)
Peer Reviewed
See detailApplications of 3D visualization in science and engineering
Burrus, Nicolas; Hoyoux, Thomas; Verly, Jacques ULg

Conference (2009)

Detailed reference viewed: 13 (2 ULg)
Peer Reviewed
See detailThe CORALS project: simulated Cosmic Radiations and Alternative Splicing.
Lambert, Charles ULg; Battout, S.; Van Oostveldt, P. et al

Conference (2009)

Detailed reference viewed: 8 (0 ULg)
See detailFORMULATION OF PEPTIDE-LOADED LIPOSOMES FOR INTRAVENOUS DELIVERY: OPTIMIZATION OF THE ENCAPSULATION EFFICIENCY
Ducat, Emilie ULg; Brion, Michael; Evrard, Brigitte ULg et al

Conference (2009)

Purpose: Print 3G is a peptidic antagonist of oncoprotein involved in breast cancer, containing 25 amino acids. The purpose of this work is to study the peptide encapsulation into PEGylated liposomes ... [more ▼]

Purpose: Print 3G is a peptidic antagonist of oncoprotein involved in breast cancer, containing 25 amino acids. The purpose of this work is to study the peptide encapsulation into PEGylated liposomes composed of SPC:CHOL:mPEG-2000-DSPE (47:47:6). Methods: Loaded unilamellar vesicles were prepared by hydration of lipid film method. Unfortunately, a loss of Print 3G was observed during the different steps of this manufacturing technique giving rise to encapsulation efficiencies (EE) close to 0 %. Thus, the freeze-thawing method was used to enhance the amount of Print 3G encapsulated into blank liposomes prepared using the above procedure. Because many factors may influence the peptide entrapment into the vesicles (number of freeze-thawing cycles (NC), lipid concentration (LC), peptide concentration (PC) and mixing time (MT)), a design of experiment (DOE) was performed (for the screening, a Plackett and Burman plan; for the optimization, a central composite design). EE were calculated in terms of quantity of peptide loaded in liposomes as a function of quantity operated (EEp) or quantity of lipids (EEl). Results: The EE obtained by the freeze-thawing method in standard conditions (Katanasaka, Ida et al., 2008; Maeda, Bharate et al., 2008), amounted to 26.20 ± 7.98 %, n=3 (EEp) and to 0.26 ± 0.074 % (EEl). Among the different considered parameters, the screening permitted to identify two factors having a positive and significant influence on the EE: NC and LC. Concerning the PC and MT, no influence was revealed. For the second part of the DOE, the positive factors were optimized and obtained results revealed a theoretical optimum at 64.75 ± 3.55 % when 11 freeze-thawing cycles were applied (NC) and for the following LC: 36.1 mM SPC, 36.1 mM CHOL and 4mM mPEG-2000-DSPE. The experimental results showed an encapsulation efficiency of 62.68 ± 2.93 %. Photon correlation spectroscopy and freeze-fracture electron microscopy were also realized to examine the liposome integrity, before and after the freeze-thawing cycles. Conclusion: Changing the manufacturing technique permitted a significant encapsulation of Print 3G into liposomes. The DOE led to a significant improvement of encapsulation efficiencies. References: (1) Katanasaka,Y., Ida,T., Asai,T., Maeda,N., Oku,N., 2008. Effective delivery of an angiogenesis inhibitor by neovessel-targeted liposomes. International Journal of Pharmaceutics, 360, 219-224. (2) Maeda,H., Bharate,G.Y., Daruwalla,J., 2008. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR effect. Eur. J Pharm Biopharm. Acknowledgements: This work was supported by the Ministry of the Walloon Region. [less ▲]

Detailed reference viewed: 91 (2 ULg)
Full Text
See detailSurvey of air-ice ocean carbon dioxyde exchange over arctic sea-ice
Heinesch, Bernard ULg; Aubinet, Marc ULg; Carnat, Gauthier et al

Conference (2009)

Detailed reference viewed: 25 (5 ULg)
See detailLes perturbateurs endocriniens et le monde agricole
Charlier, Corinne ULg

Conference (2009)

Detailed reference viewed: 16 (5 ULg)
Full Text
See detailMacrophyte biological index for rivers (MBIR) application for an ecological assessment of walloon rivers, prelilminary investigations.
Sossey Alaoui, Khadija ULg; Galoux, D.; Rosillon, Françis ULg

Conference (2009)

Samples were collected from 45 sites along the Walloon river network in 2007, in accordance with the Water Framework Directive (WFD, European Union, 2000), used to define the overall ecological status of ... [more ▼]

Samples were collected from 45 sites along the Walloon river network in 2007, in accordance with the Water Framework Directive (WFD, European Union, 2000), used to define the overall ecological status of rivers. Within each collected sample, macrophyte data were gathered at species level and the main water quality parameters were analyzed. This involved the use of two approaches: firstly, methods of ordination and classification (Principal Component Analysis and Multiple Factorial Analysis) and secondly, aquatic macrophyte community indexes. The Macrophyte Biological Index for Rivers (MBIR) was used to define the ecological status of the macrophyte community in response to eutrophication pressure. Four trophic qualities were detected in all the monitored stations: 56% of the sites showed a good trophic quality, with the Ardennes region in the leading position and only 2% of the sites showed a poor trophic quality. A Multiple Factorial Analysis (MFA) made it possible to regroup the species according to their ecological affinities and to specify their indicator values in relation to some abiotic parameters. As a result, a rivers typology was outlined based on this analysis. The dendrogram of the Hierarchical Cluster Analysis (HCA) gave three clusters determined by active variables of each compartment that defined functional parts of the Walloon network: Chiloscyphus polyanthos (L.) Corda, Rhynchostegium riparioides(Hedw.)C.Jens., Fontinalis squamosa(Hedw) and Ranunculus penicillatus (Dum.)Bb. showed an oligotrophic status and low mineralization in the Ardennes (GI), while P. pectinatus(Linne), Cladophora glomerata(Linnaeus)proved to be found more often in eutrophicated waters in the Region limoneuse (GIII). Pellia endvifolia (Dicks.)Dum, Fissidens crassipes(Br.Eur);Cinclidotus riparius (Web. & Mohr.) appeared in the Condroz and Famenne, rivers characterized by a high concentration of nitrogen (N-35. NO3-) (GII). [less ▲]

Detailed reference viewed: 180 (9 ULg)
Peer Reviewed
See detailFonctions attentionnelles et exécutives dans la dyspraxie développementale
Lejeune, Caroline ULg; Catale, Corinne ULg; Meulemans, Thierry ULg

Conference (2009)

La dyspraxie développementale se manifeste principalement par des difficultés motrices qui interfèrent avec différentes situations de la vie quotidienne (écriture, dessin, habillage, …). Ces troubles du ... [more ▼]

La dyspraxie développementale se manifeste principalement par des difficultés motrices qui interfèrent avec différentes situations de la vie quotidienne (écriture, dessin, habillage, …). Ces troubles du geste, qui touchent environ 6 % des enfants de 5 à 11 ans, entraînent de lourdes conséquences sur les plans familial, scolaire et social. Plusieurs études ont montré qu’un déficit des capacités d’inhibition, de planification et de mémoire de travail était fréquemment observé chez les enfants souffrant de dyspraxie. Toutefois, en raison des nombreux problèmes méthodologiques rencontrés dans ces recherches (et plus particulièrement liés à l’absence de contrôle de la présence ou non du trouble de l’attention avec/sans hyperactivité – TDA/H - chez la population d’enfants dyspraxiques), les relations entre les troubles attentionnels et les troubles moteurs restent encore à l’heure actuelle mal comprises. L’objectif de cette étude vise à dégager, au travers d’une évaluation du fonctionnement attentionnel et exécutif, le profil neuropsychologique d’enfants diagnostiqués dyspraxiques, et ce en contrôlant la présence d’un TDA/H. Nous avons administré à 23 enfants dyspraxiques âgés de 6 à 12 ans et 23 enfants de contrôle (appariés sur base de l’âge, du sexe et du niveau d’études des parents) des tâches attentionnelles (alerte, attention sélective et divisée) de la batterie TEA et des épreuves exécutives (inhibition [Stroop et Go/No Go], flexibilité cognitive [TEA], mémoire de travail [BTT et mise à jour de TEA] et planification [Tour de Londres]). Les analyses de comparaison de moyennes indiquent que les enfants dyspraxiques présentent des performances inférieures à celles des enfants de contrôle pour l’essentiel des tests neuropsychologiques administrés. Toutefois, deux tiers des enfants dyspraxiques de notre échantillon présentent un trouble de l’attention (critères du DSM-IV). L’analyse des résultats au sein du groupe « dyspraxique sans TDA », permet de montrer que les difficultés de planification, d’attention sélective visuelle, d’inhibition motrice, de mémoire à court terme (BTT et mise à jour) sont spécifiques à la dyspraxie et donc indépendant de la présence d’un trouble de l’attention. En conclusion, cette étude préliminaire montre qu’une grande proportion d’enfants qui présentent une dyspraxie souffre également d’un trouble de l’attention. L’analyse du profil des enfants dyspraxiques montre des difficultés qui touchent l’ensemble des fonctions attentionnelles et exécutives. Toutefois, les difficultés d’analyse visuelle, de planification et de mémoire de travail semblent, quant à elles, spécifiques à la dyspraxie développementale. Des études futures réalisées sur un plus grand nombre de participants permettraient de confirmer cette hypothèse. [less ▲]

Detailed reference viewed: 888 (23 ULg)
Peer Reviewed
See detailEco-éthologie de la population de bonobos récemment découverte dans l’ouest de la République Démographique du Congo
Serckx, Adeline ULg; Huynen, Marie-Claude ULg; Beudels-Jamar, Roseline

Conference (2009)

The bonobo, Pan paniscus, an endemic primate of the DRC, forms with the chimpanzee, Pan troglodytes, the pair of species closest to humans. Classified as “Endangered” by the IUCN, it’s seriously ... [more ▼]

The bonobo, Pan paniscus, an endemic primate of the DRC, forms with the chimpanzee, Pan troglodytes, the pair of species closest to humans. Classified as “Endangered” by the IUCN, it’s seriously threatened by the degradation of the forests. Only the creation of protected areas large enough and properly managed can improve its status but requires a good knowledge of the eco-ethology of the local populations. Our project will focus on studying a bonobo population recently discovered in the region of the Lake Tumba, in the west of the DRC. It is characterized by densities never encountered elsewhere, and a preliminary study has revealed significant differences in habitat and food resources in comparison to these of eastern populations. We will contribute to a recently established WWF conservation program by gathering eco-ethological data on bonobos, data that will allow identifying areas to protect, their boundaries and management measures to implement. To do this, we will study the diet of bonobos via direct and indirect observations of their behavior. We will also study the party size and its composition and identify underlying environmental factors. We will assess the bonobos’ home range size and pattern of displacement, which we will correlate with the abundance of food resources to determine whether there is a pattern of occupation of time and space specific to this population. [less ▲]

Detailed reference viewed: 36 (8 ULg)
Full Text
See detailImportance de l'école dans le développement rural
Duquesne, Brigitte ULg

Conference (2009)

Detailed reference viewed: 21 (6 ULg)
See detailEarly land plant evolution: a tremendous success story.
Gerrienne, Philippe ULg

Conference (2009)

Detailed reference viewed: 6 (0 ULg)
See detailThe socio-economic integration of migrants in Spain
Brey, Elisa ULg

Conference (2009)

Detailed reference viewed: 9 (0 ULg)
See detailDevelopment of a quantitative method to detect trace amounts of hazelnut and soy allergens in food
Dobson, Rowan ULg; Fourdrilis, Séverine; Kirsch, Stéphanie ULg et al

Conference (2009)

Detailed reference viewed: 22 (3 ULg)
Full Text
Peer Reviewed
See detaile-Demos, We'll Show You What We've Got !"
Lecomte, Béatrice ULg

Conference (2009)

Detailed reference viewed: 40 (17 ULg)
Peer Reviewed
See detailDetecting preferential flow and transport in soils using electrical resistivity tomography
Vanderborght, Jan; Oberdoerster, Christoph; Garré, Sarah ULg et al

Conference (2009)

Detailed reference viewed: 47 (1 ULg)
See detailLe Dévonien: des mousses à l'arbre.
Gerrienne, Philippe ULg

Conference (2009)

Detailed reference viewed: 4 (0 ULg)
See detailUncertainty of carbon dioxide fluxes introduced by different high-pass filtering methods
Ibrom, Andreas; Geißler, Simon; Laffineur, Quentin ULg et al

Conference (2009)

Detailed reference viewed: 15 (5 ULg)
Peer Reviewed
See detailAutonomous Learning of Object-specific Grasp Affordance Densities
Detry, Renaud ULg; Başeski, Emre; Krüger, Norbert et al

Conference (2009)

Detailed reference viewed: 25 (2 ULg)
See detailDroits d'enregistrement et TVA
Bourgeois, Marc ULg

Conference (2009)

Detailed reference viewed: 4 (0 ULg)
See detailSteps Prior to the RAI Instrument Implementation in Belgium
Degey, S; Tancredi, A; Renard, F et al

Conference (2009)

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailIRF3 is required for induction of allergic airway inflammation by dendritic cells
Marichal, Thomas ULg; Bedoret, Denis; Goriely, M. et al

Conference (2009)

Detailed reference viewed: 46 (11 ULg)
See detailThe beta Cephei star HD180642: Seismic modelling
Thoul, Anne ULg

Conference (2009)

Detailed reference viewed: 1 (0 ULg)
See detailLes premières plantes terrestres (Embryophytes) : origine et diversification - première partie.
Gonez, Paul ULg; Prestianni, Cyrille ULg; Strullu-Derrien, Marie-Christine et al

Conference (2009)

Detailed reference viewed: 23 (4 ULg)
See detailInfluences de l'environnement sur la fonction endocrinienne
Charlier, Corinne ULg

Conference (2009)

Detailed reference viewed: 8 (4 ULg)
See detailLes sacro-iliaques
Massart, Nicolas ULg

Conference (2009)

Detailed reference viewed: 41 (14 ULg)
See detailFootball, nationalisme et gouvernance
Tuñón, Jorge; Brey, Elisa ULg

Conference (2009)

Detailed reference viewed: 14 (0 ULg)
See detailHet leerdercorpus Nederlands in theorie en in de praktijk
Perrez, Julien ULg; Degand, Liesbeth

Conference (2009)

Detailed reference viewed: 27 (0 ULg)
See detailOnline assessment of the quality of care in elderly (Belgium)
Tancredi, A; Renard, Florence ULg; Degey, S et al

Conference (2009)

Detailed reference viewed: 14 (0 ULg)
Peer Reviewed
See detailOn the use of posture verbs by French-speaking learners of Dutch : a corpus-based study.
Lemmens, Maarten; Perrez, Julien ULg

Conference (2009)

Detailed reference viewed: 4 (0 ULg)
Peer Reviewed
See detailSearching for traces of life in ancient stromatolites down to the nanoscale.
Lepot, Kevin ULg; Philippot, Pascal; Benzerara, Karim et al

Conference (2009)

Detailed reference viewed: 26 (1 ULg)
Peer Reviewed
See detailAgroecology and the emergence of "Publics"
Stassart, Pierre M ULg

Conference (2009)

Detailed reference viewed: 17 (1 ULg)
Peer Reviewed
See detailStudy of antibiotics influence on activated sludge behaviour via analysis of exopolymeric substances
Avella, Catalina; Essendoubi, M.; Louvet, Jean-Noël ULg et al

Conference (2009)

Detailed reference viewed: 7 (0 ULg)
Peer Reviewed
See detailRestauração dos campos rupestres: efeitos de espécies lenhosas sobre as comunidades adjacentes
Le Stradic, Soizig ULg; Buisson, Elise; Negreiros, Daniel et al

Conference (2009)

Detailed reference viewed: 3 (0 ULg)
See detailPerturbations endocriniennes liées aux polluants environnementaux
Charlier, Corinne ULg

Conference (2009)

Detailed reference viewed: 36 (10 ULg)
See detailThermal manipulations of broiler embryos during late incubation and their immediate and long-lasting effects
Willemsen, H.; Everaert, Nadia ULg; Tona, K. et al

Conference (2009)

Detailed reference viewed: 9 (0 ULg)
See detailRéponse à Harm Pinkster: Relatieve bijzinnen in het Latijn
Longrée, Dominique ULg

Conference (2009)

Detailed reference viewed: 7 (1 ULg)
See detailApplication of a 3-D Super Ensemble to ocean forecast
Lenartz, Fabian ULg; Barth, Alexander ULg; Beckers, Jean-Marie ULg et al

Conference (2009)

Super Ensemble (SE) techniques have recently allowed improving the forecast of various important oceanographic parameters, such as the significant wave height, the speed of sound or the surface drift, by ... [more ▼]

Super Ensemble (SE) techniques have recently allowed improving the forecast of various important oceanographic parameters, such as the significant wave height, the speed of sound or the surface drift, by correcting the prediction at a single or multiple locations, where data were available during the whole training period. However, nowadays common observation systems, such as satellite imagery or drifters, do not always provide information at the exact same locations, hence it is necessary to generalize the approach in order to take benefit of every image or track available. In this study, we try and apply a SE, fed with remote sensing and gliders data, to 3-D hydrodynamic models. The basic idea on which rely the SE methods is that a certain combination of several model runs and possibly data could yield better results than just one single model, even if it has a higher temporal or spatial resolution. As the most efficient techniques are the ones using observations, they rapidly developed and increased in complexity by copying what had been done in the data assimilation community; getting from the simple ensemble mean of the model outputs to their linear combination based on a particle filter. In our present study, we have decided to use the Kalman filter (KF) as it alleviates the need of an a priori determination of the training period length, and does not require the run of a very large ensemble of members. In addition, we apply it in a 3-D framework in order to take benefit of the spatial information contained by each source of measurements. For example, satellite images of sea surface temperature (SST) are very useful to correct the value of this parameter, but depending on the structure of the water column, it can also give a precious guess of how warm or cold is the ocean at 20 m deep. In our experiment the domain of interest is the Ligurian Sea during the last week of September, when part of the set-up for the CalVal08 campaign (SiC Charles Trees) had already taken place. The data assimilated during the training of the filter are SST images from AVHRR, as well as temperature and salinity profiles from two Rutgers University gliders. The models used for the study are three nested models of NCOM, run without data assimilation. The two considered variables are the temperature and the salinity. As our method is designed to work in a multivariate way, salinity forecast can possibly be improved by observing temperature profiles. Statistics are computed for both the training and the testing periods with an independent set of data. In four test cases, we review the impact of both the nature of the assimilated data, and the formulation of the model covariance matrix. At the end, we show that, on the basis of previous model outputs from which we’ve drawn an estimate of the model covariance, RMS error of the forecast in the whole 3-D domain can be reduced by 30%, thanks to the only assimilation of satellite SST images. [less ▲]

Detailed reference viewed: 46 (5 ULg)
See detailComa, consciousness and the brain
Noirhomme, Quentin ULg

Conference (2009)

Detailed reference viewed: 7 (1 ULg)
See detailIdentification, cartographie et gestion des Forêts à Haute Valeur de Conservation : cas de la concession Pallisco, Cameroun
Julve Larrubia, C.; Sépulchre, F.; Philippart, Julien ULg et al

Conference (2009)

Detailed reference viewed: 48 (11 ULg)
See detailTransformation identitaires en cours de formation initiale des enseignants: axes d'une grille de réflexivité sur le métier
Dejean, Karine ULg

Conference (2009)

Cette communication porte sur l’analyse des transformations identitaires exprimées dans les discours des enseignants en formation initiale. Cette analyse nous a permis de dégager des axes de ... [more ▼]

Cette communication porte sur l’analyse des transformations identitaires exprimées dans les discours des enseignants en formation initiale. Cette analyse nous a permis de dégager des axes de transformation qui pourront servir d’outils dans le cadre de séances de réflexivité collective et individuelle avec les futurs enseignants en leur offrant des éléments d’intelligibilité pour les aider à se situer par rapport à leur propre parcours de développement et par rapport aux différentes attentes institutionnelles à leur égard. [less ▲]

Detailed reference viewed: 18 (1 ULg)
Full Text
See detailAchromatization of solar concentrator thanks to diffractive optics
Languy, Fabian ULg; Lenaerts, Cedric ULg; Loicq, Jerôme ULg et al

Conference (2009)

Refractive solar concentrators suffer from important chromatic aberration. To enhance solar cell performance and increase the concentrating ratio, we propose an hybrid (diffractive/refractive) lens which ... [more ▼]

Refractive solar concentrators suffer from important chromatic aberration. To enhance solar cell performance and increase the concentrating ratio, we propose an hybrid (diffractive/refractive) lens which allows a more uniform flux density and an achromatized (in the sense of achromatic doublet) illumination of the cell. To solve the problem of high diffraction efficiency, we turn to multilayer diffractive lenses to have broadband high diffraction efficiency optimized on solar spectrum. Rigorous coupled wave analysis simulations were performed in order to check the validity of scalar theory, they led to a new order of magnitude for the ratio period/wavelength which has been found to be around 100 in place of 10. [less ▲]

Detailed reference viewed: 201 (33 ULg)
Full Text
See detailL'agriculture familiale africaine au coeur des Objectifs du Millénaire pour le Développement (OMD)
Berti, Fabio ULg; Lebailly, Philippe ULg

Conference (2009)

L’agriculture familiale africaine est concernée directement par l’Objectif 1 du Millénaire pour le Développement, de réduire de moitié d’ici 2015 l’extrême pauvreté et la faim. En effet, selon la plupart ... [more ▼]

L’agriculture familiale africaine est concernée directement par l’Objectif 1 du Millénaire pour le Développement, de réduire de moitié d’ici 2015 l’extrême pauvreté et la faim. En effet, selon la plupart des observateurs, 70% des pauvres sont localisés dans les zones rurales et sont agriculteurs. Dans ce contexte, il importe de s’interroger sur l’avenir des exploitations agricoles familiales en Afrique. Après avoir présenté la problématique générale de l’exploitation agricole familiale dans le développement, les auteurs présentent une analyse au départ des constats qu’ils ont pu réaliser, respectivement pour les filières de rente de la zone forestière au Cameroun et pour le coton, dans plusieurs pays d’Afrique de l’Ouest. Les analyses sont réalisées à partir des observations effectuées au départ de différentes études financées essentiellement par la Commission européenne au cours de ces dernières années. Il en résulte que le terme « agriculture familiale » recouvre des réalités très différentes avec une différenciation de plus en plus poussée des exploitations agricoles. Dans le même temps, il subsiste de nombreuses exploitations familiales plus « traditionnelles » mêlant des logiques d’autoconsommation et de marché avec des dotations en facteurs plus inégales et donc plus vulnérables. L’enjeu primordial des politiques agricoles qui seront définies sera précisément de prendre en considération la dimension spécifique de ce type d’exploitation, cible prioritaire dans la lutte contre la pauvreté. L’orientation des politiques mises en œuvre autour du seul objectif de la production de biens agricoles ne permettra pas de réduire les disparités internes et souvent croissantes observées. Il convient donc d’intégrer les dimensions sociales et environnementales dans les objectifs des politiques agricoles à mettre en œuvre. [less ▲]

Detailed reference viewed: 129 (25 ULg)
See detailVanadium oxide-based mesoporous films as positive electrode material in Li-ion batteries
Krins, Natacha ULg; Caes, Sébastien ULg; Arrebola, José-Carlos et al

Conference (2009)

Detailed reference viewed: 2 (0 ULg)
Full Text
Peer Reviewed
See detailDust exposure exacerbates the expression of ptx3, a recently discovered acute phase protein, in horses’ airways
Ramery, Eve ULg; Bureau, Fabrice ULg; Lekeux, Pierre ULg

Conference (2009)

Heaves is a common cause of recurrent airway obstruction (R.A.O) that occurs in mature horses stabled in a dusty environment. The long pentraxin PTX3 play an important role in the host defence and over ... [more ▼]

Heaves is a common cause of recurrent airway obstruction (R.A.O) that occurs in mature horses stabled in a dusty environment. The long pentraxin PTX3 play an important role in the host defence and over-expression of PTX3 may contribute to airways injury. Therefore, we hypothesised that PTX3 may have relevance in the understanding of the pathogenesis of recurrent airway obstruction (R.A.O). In the present study, we first investigated the equine PTX3 (ePTX3) structure by cloning, sequencing and western-blotting. A 120pb deletion was found in the second exon of ePTX3 in comparison to human PTX3. Moreover, an alternative splicing occurs with complete deletion of the second exon, resulting in two forms of the protein, “spliced” (32 kD) and “full length” (42 kD). The pentraxin domain is very well conserved in the two forms with 94% of amino-acids conserved between equines and humans. These findings could have implications for the comprehension of the function of each domain of the protein. Then, we studied the effects of dust exposure and subsequent R.A.O crisis on ePTX3 expression in the broncho-alveolar lavage fluid (BALF) and the bronchial epithelial cells. PTX3 could be detected in BALF macrophages, neutrophils, eosinophils and bronchial epithelial cells. It was over-expressed in the BALF supernatant from RAO-affected horses in crisis. Dust exposure induced PTX3 in BALF macrophages either in healthy horses or in R.A.O-affected horses. Conversely, PTX3 was strongly over-expressed in the bronchial epithelial cells from R.A.O-affected horses in crisis. Considering epithelial cells as one of the major cell types in the airways, PTX3 produced at this level may play an important role in inflammatory process. Moreover, it suggests that dust-induced expression of PTX3 is differentially regulated in macrophages and bronchial-epithelial cells. A JNK-dependant, NFκB-independent regulatory pathway has been described in lung epithelial cells. A comparable mechanism could be involved in bronchial epithelial cells. If this is confirmed, PTX3 expression in respiratory epithelial cells could be therapeutically targeted. [less ▲]

Detailed reference viewed: 21 (1 ULg)
See detailDevelopment of an active H maser: first results
Mandache, Cipriana ULg; Léonard, D.; Bastin, Thierry ULg

Conference (2009)

Detailed reference viewed: 38 (8 ULg)
See detailModelling error of a hydrodynamic model of the Mediterranean Sea
Vandenbulcke, Luc ULg; Rixen, M.; Beckers, Jean-Marie ULg et al

Conference (2009)

Detailed reference viewed: 15 (2 ULg)
Peer Reviewed
See detailDoes music education facilitate the perception of prosodic prominence in a foreign language?
Rasier, Laurent ULg; Degrave, Pauline; Hiligsmann, Philippe

Conference (2009)

Detailed reference viewed: 10 (0 ULg)
See detailImplants dans le secteur esthétique: choix du timing et de la technique chirurgicale.
LAMBERT, France ULg

Conference (2009)

Les résultats esthétiques en implantologie sont déterminés par une harmonie tissulaire et prothétique. Plusieurs techniques chirurgicales sont décrites et le choix de celle-ci est déterminant pour obtenir ... [more ▼]

Les résultats esthétiques en implantologie sont déterminés par une harmonie tissulaire et prothétique. Plusieurs techniques chirurgicales sont décrites et le choix de celle-ci est déterminant pour obtenir un résultat esthétique optimal. Cet exposé décrit des techniques chirurgicales telles que: extraction/implantation immédiate, gestion d'alvéoles ou encore régénération osseuse. L'objectif est, à partir d'une situation clinique initiale, de déterminer le choix de la technique idéale ainsi que le timing chirurgical . [less ▲]

Detailed reference viewed: 16 (0 ULg)
Full Text
Peer Reviewed
See detailCo-transplantation of mesenchymal stem cells might mitigate acute GvHD without abrogating graftversus- tumour alloreactivity after allogeneic transplantation with non-myeloablative conditioning
Baron, Frédéric ULg; WILLEMS, Evelyne ULg; LECHANTEUR, Chantal ULg et al

Conference (2009)

Background: Results of nonmyeloablative HCT in pts with HLA-mismatched donors have been disappointing due to high incidence of graft rejection and severe acute GVHD. Recent studies have suggested that ... [more ▼]

Background: Results of nonmyeloablative HCT in pts with HLA-mismatched donors have been disappointing due to high incidence of graft rejection and severe acute GVHD. Recent studies have suggested that infusion of mesenchymal stem cells (MSC) the day of HCT might promote engraftment and prevent acute GVHD after myeloablative allogeneic HCT. However, some studies suggested that MSC co-infusion might abrogate graft-versus-host alloreactivity and graft-versus-tumor effects. This prompted us to investigate whether MSC infusion a few hours before HCT could allow nonmyeloablative HCT from HLA-mismatched donors to be performed safely (i.e. with a 100-day incidence of nonrelapse mortality < 35%). Methods: 20 patients with hematological malignancies were given MSC (1-2 x 10E6 cells/kg) from third party donors a few hours before PBSC from HLA-mismatched unrelated donors, after conditioning with 2 Gy TBI and fl udarabine 90 mg/m. Postgrafting immunosuppression included tacrolimus (day -3 to +180; tapered by day +365) and mycophenolate mofetil (tid days 0 to +42). HLA-compatibility was assessed at the HLA-A, -B, -C, -DRBI and DQBI loci: 13 pairs were mismatched for at least one HLA class I antigen (including 4 pairs who were also mismatched for 1 HLA-class II antigens (n=3) or 1 HLA-class I allele (n=1)), 1 pair was mismatched for 2 HLA class II alleles, while 6 pairs were mismatched for a single HLA class I (n=3) or HLA class II (n=3) alleles. Results: Median follow-up for surviving patients was 288 (range, 76-571) days. One patient with secondary AML had primary graft rejection, while the remaining 19 patients had sustained engraftment. Median donor T-cell chimerism levels on days 28, 100, 180 and 365 after HCT were 90%, 98%, 96%, and 98%, respectively. Grade II, III and IV acute GVHD were seen in 5, 2 and 1 patients, respectively, while 7 experienced NIH moderate/severe chronic GVHD. Three of 7 patients with measurable disease at transplantation achieved complete remission on days 41, 104 and 353 after HCT. Two patients died of nonrelapse causes on days 74 and 114 after HCT, while 3 died of disease progression. Projected 1-yr overall and progressionfree survivals were 77% and 61%, respectively. Conclusions: HLA-mismatched nonmyeloablative HCT with MSC co-infusion appeared to be safe, with MSC co-infusion possibly mitigating graft-versus-host alloreactivity without abrogating graft-versus-tumor effects. Survival is encouraging. [less ▲]

Detailed reference viewed: 18 (3 ULg)
Peer Reviewed
See detailIntentional patina of metal archaeological artefacts; a non-destructive investigation of Egyptian and Roman museum treasures
Mathis, François ULg; Aucouturier, Marc; Robcis, Dominique et al

Conference (2009)

Detailed reference viewed: 9 (0 ULg)
Full Text
See detailCarbon cycling in the mixolimnion of Lake Kivu (East Africa)
Borges, Alberto ULg; Descy, J.-P.; Delille, Bruno ULg et al

Conference (2009)

Detailed reference viewed: 25 (5 ULg)
Peer Reviewed
See detailGeneration of Long-lived Entanglement on Demand in Remote Qubits
Schilling, U.; Thiel, C.; Bastin, Thierry ULg et al

Conference (2009)

Detailed reference viewed: 8 (2 ULg)
See detailDiversité et limites de la vie
Wilmotte, Annick ULg; Javaux, Emmanuelle ULg

Conference (2009)

Detailed reference viewed: 5 (4 ULg)
Peer Reviewed
See detailImpact of Prosthesis-Patient Mismatch on Short-term Mortality Following Mitral Valve Replacement.
Magne, Julien ULg; Mathieu, P; Dumesnil, JG et al

Conference (2009)

Detailed reference viewed: 3 (0 ULg)
Peer Reviewed
See detailRegional mapping of pedogeochemical background in Southern Belgium: Combining grid-survey measurements with existing maps of the physical environment.
Colinet, Gilles ULg; Bock, Laurent ULg

Conference (2009)

Among natural factors driving the soil content in metallic trace elements (MTE), the geochemical background is often deemed as a sound base for the detection of contaminations. Numerous studies have shown ... [more ▼]

Among natural factors driving the soil content in metallic trace elements (MTE), the geochemical background is often deemed as a sound base for the detection of contaminations. Numerous studies have shown the difficulties to take into account the multi-dimensionnality of the spatial variability of most soil properties. As far as a detailed soil map is available for Belgium, the relevance of its information was investigated at various spatial scales in the Walloon Region (Southern Belgium), from the plot to the entire region, to evaluate the feasibility of a multi-scale mapping of geochemical background. The soil properties of 410 plots from the regional forest soil monitoring and the relationships with informations related to the physical environment (lithology, soil types...) were investigated through multivariate statistical analysis. Some processes of integration of point measurements and qualitative information were also explored. At the regional scale, some long-range spatial structures could be identified. These result mainly from the geological structure of the Walloon region, where the lithological zonation is rather clearly marked. The soil map (texture and nature of stone charge) appears relevant at that scale too but does need a generalization process and fails however to differenciate the intra-type soil spatial variability. [less ▲]

Detailed reference viewed: 30 (3 ULg)