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See detailFuture projections of the Greenland ice sheet surface mass balance simulated by the regional climate model MAR forced by three CMIP5 global models.
Fettweis, Xavier ULg; Franco, Bruno ULg; Lang, Charlotte ULg et al

Conference (2012, September 11)

As part of the ICE2SEA project, the regional climate model MAR was forced by the global models HadCM3 and ECHAM5 for making future projections of the Greenland Ice Sheet (GrIS) Surface Mass Balance (SMB ... [more ▼]

As part of the ICE2SEA project, the regional climate model MAR was forced by the global models HadCM3 and ECHAM5 for making future projections of the Greenland Ice Sheet (GrIS) Surface Mass Balance (SMB) over 1980-2099 at a resolution of 25km. However, the comparison with MAR forced by the ERA-40 reanalysis over 1980-1999 shows that MAR forced by these GCMs is not able to represent reliably the current SMB due to biases in the general circulation and in the free atmosphere summer temperature modelled by these GCMs around the GrIS. That is why, we present here first results of MAR forced by the next generation of GCMs from the CMIP5 data base (CanESM2, NorESM1 and MIROC5 here). The comparison with the ERA-INTERIM forced MAR simulations over current climate is a lot of better, which increases the reliability and the interest of these new MAR projections. In addition, the new scenarios (RCP 2.6, 4.5, 6.0 and 8.5) of the next IPCC Assessment Report (AR5) are used here. These new simulations show notably that the response of SMB to rising temperature is not a linear function of the temperature anomalies due to the positive albedo feedback which enhances the surface melt. For 2100, in case of extreme rising temperature (RCP 8.5 scenario), MAR simulates a surface GrIS mass loss corresponding to a cumulated sea level rise (SLR) of about 15 cm since 2000! Mainly the changes in SMB and in surface energy balance will be discussed here and estimations of the GrIS surface melt contribution to the SLR using all the CMIP5 outputs will be given. [less ▲]

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See detailEnfance, culture, morale. Autour de Sartre lecteur et relecteur d’Alain
Cormann, Grégory ULg

Conference (2012, September 11)

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See detailSeveral years El Niño forecast using a wavelet-based mode decomposition
Nicolay, Samuel ULg; Fettweis, Xavier ULg

Conference (2012, September 10)

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See detailDiagnosis of parathyroid carcinoma: potential role of PTH laboratory assays
CAVALIER, Etienne ULg

Conference (2012, September 08)

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See detailGénitif -aes/-es pour -ae : hellénisme ou vulgarisme ?
Rochette, Bruno ULg

Conference (2012, September 07)

The origin of the genitive –aes/-es for –ae is difficult to establish. The most common opinion about this type of genitive, which occurs in epigraphical and, in more reduced proportions, in papyrological ... [more ▼]

The origin of the genitive –aes/-es for –ae is difficult to establish. The most common opinion about this type of genitive, which occurs in epigraphical and, in more reduced proportions, in papyrological sources (not, insofar as I know, in literary texts) especially for women’s personal names (but also in common nouns), is that it comes from the Greek. Beside the influence of Greek, several theories can be found about the origin of this particularity, commonly attested even in Republican Latin names. Indeed, in vulgar Latin, the –es ending genitive (used as dative as well) was frequently used from the 1st c. B.C. This phenomenon can be observed in Rome, in Italy and in the provinces (not only in western provinces, but also in eastern provinces, where the influence of Greek could have been stronger). In the epigraphical texts, this type of genitive occurs frequently in Greek personal names among some social groups (low classes). The origin of the dedicants (native, Greek or Oriental, i.e. Greek-speaking persons) must be taken into account and, for the common nouns, the contextualization is very important. I’ll focus on the inscriptions from Asia Minor and compare them with other regions as Italia X and Pannonia to see : 1° whether –aes/-es are two distinctive phenomena or two variants of the same phenomenon and 2° if this particularity has been used as a typical feature to point out the Greek origin of the person(s) mentioned in the inscription or the bilingual character of the community which has produced the text. [less ▲]

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See detailIl latino dell'Alcestis Barcinonensis
Macedo, Gabriel ULg

Conference (2012, September 06)

This paper presents a linguistic description of the Barcelona Alcestis, an anonymous Latin poem contained in a fourth century papyrus codex. Traces of Vulgar Latin are identified in the orthography, which ... [more ▼]

This paper presents a linguistic description of the Barcelona Alcestis, an anonymous Latin poem contained in a fourth century papyrus codex. Traces of Vulgar Latin are identified in the orthography, which reveals the language as it was heard, understood and spoken by the copyist, whereas the syntactic features of the text can inform us about the language used by the author in the time of the composition. [less ▲]

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See detailImages et concepts dans le métaphorologie de Hans Blumenberg
Zincq, Aurélien ULg

Conference (2012, September 06)

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See detailHeur(t)s et malheurs dans le contre-transfert
Naziri, Despina ULg

Conference (2012, September 06)

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See detailFunctional connectivity changes in hypnotic state measured by fMRI
Demertzi, Athina ULg; Soddu, Andrea ULg; VANHAUDENHUYSE, Audrey ULg et al

Conference (2012, September 06)

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See detailThe sensitivity of optimal rail‐road terminal locations to intermodal freight costs variations
Carreira, Joana; Santos, Bruno; Limbourg, Sabine ULg

Conference (2012, September 05)

In the last decades, the market of goods became globalized, increasing international trade relations and the demand for long distance transportation. As a consequence of the larger distances traveled and ... [more ▼]

In the last decades, the market of goods became globalized, increasing international trade relations and the demand for long distance transportation. As a consequence of the larger distances traveled and of the containerization of goods, maritime transportation became more efficient and reliable. In the hinterland, intermodal (rail-road) freight transportation emerged as a competitive alternative to truck-only transportation. In one of its possible meanings, intermodal freight transportation is the multimodal chain of container-transportation services [1] that, e.g., brings containers from (or to) the seaport by barge or rail to (or from) an intermodal terminal in the hinterland from where they are shipped by truck to their final destination (or origin). This study focus on inland intermodal freight transport, in particular, on the rail–truck transport of cargo containers in Belgium. This European country has a long rail system and in the last years has readapted this system in order to handle with containerized cargo. Since 2004, some rail-road terminals have been built and new intermodal services between the seaports of Belgium have been established. In addition, with the aim of promoting the modal share of intermodal rail-road transport, the federal government of Belgium started subsidizing part of the rail transport cost and of the transshipments costs at the rail-road terminals. With these investments the intermodal freight flows in Belgium have increased. [less ▲]

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See detailDistribution and identification of molecular interactions between tomato roots and bacterial biofilms
Debois, Delphine ULg; Jourdan, Emmanuel ULg; Ongena, Marc ULg et al

Conference (2012, September 05)

Some non pathogenic microorganisms evolving in the root micro-environment can trigger a positive effect on plant, increasing host defense against disease or/and directly inhibiting growth of pathogen in ... [more ▼]

Some non pathogenic microorganisms evolving in the root micro-environment can trigger a positive effect on plant, increasing host defense against disease or/and directly inhibiting growth of pathogen in soil (1). To initiate both phenomena leading to biocontrol activity, microorganisms use plant exudates to grow on roots and to produce in-situ active compounds. In Bacilli, cyclic lipopeptides of the surfactin, iturin and fengycin families represent important antibiotics involved in biocontrol (2). Recent studies in microbiology allowed a better understanding of plant microorganism interactions but few has been done at the molecular level. In this study, MALDI MS imaging has been used to study the nature of the secreted lipopeptide molecules, their relative quantity and their distribution in the root’s environment. Disinfected tomato seeds were first germinated at 28°C in sterile conditions for germination. Seedlings were then placed in Petri dish on ITO glass slide recovered with a thin layer of plant nutritive solution (Hoagland) containing 1,75% of agar and treated with freshly-grown cells of Bacillus amyloliquefaciens S499. Petri dishes were finally incubated vertically in phytotron at 28°C with a 16h photoperiod. Different root age / time of incubation were studied: 13 / 3; 13 / 7; 21 / 14 and 39 / 32. Control tomato root (without bacterial treatment) of the same ages were also analyzed (13 / 0; 21 / 0 and 42 / 0. For MALDI imaging experiments, the ITO slide was removed from the agar and dried in a dessiccator under vacuum. The matrix solution (α-cyano-hydroxycinnamic acid, 5mg/mL in ACN/0.2% TFA 70/30) was applied with an ImagePrep automated sprayer (Bruker Daltonics). An UltraFlex II TOF/TOF and a Solarix FT-ICR mass spectrometers were used to record molecular cartographies. The average mass spectra recorded around the tomato root (2-3 mm on both sides of the root) showed that lipopeptides were major compounds detected on the agar. The relative intensity of lipopeptides families varied with respect to the age of the root/biofilm system. In the 13/3 system, 3 homologues of surfactins were essentially detected (C13, C14 and C15), with very few iturins and fengycins. Their localizations were identical, whatever the considered homologue. Then the production of iturin and fengycin families increases in older systems (13/7 and 21/14) and a novel homologue of surfactin is detected (C12). Some variations in localizations within families may be observed (around the root or at the close vicinity of it in function of the considered homologue or alkali adduct). Then for the oldest system we studied, iturins and fengycins are not detected anymore and the localization of surfactins is less precise. In the 39/32 system, we also detected unknown compounds at 986.6, 1000.6, 1014.7 and 1028.7 m/z. The mass range of these compounds allied to the mass difference between two consecutive ion peaks let us think that these unknown compounds could be a new lipopeptide family. Investigations are in progress to identify these new secondary metabolites of Bacillus amyloliquefaciens. [less ▲]

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See detailSustainability, Strategy and Management Control: A Review of the Literature
Crutzen, Nathalie ULg; Herzig, Christian

Conference (2012, September 04)

The purpose of this research is to explore the emerging body of literature on the relationship between sustainability, strategy and management control. Our way to organise and present the literature aims ... [more ▼]

The purpose of this research is to explore the emerging body of literature on the relationship between sustainability, strategy and management control. Our way to organise and present the literature aims to both structure the state of our knowledge in this area and stimulate others to contribute to a shared and better understanding of this field of research. Previous research has underlined that (sustainability) management control systems play a key role in shaping processes of (sustainability/CSR) strategy formulation and implementation (e.g. Simons, 1990; Epstein and Wisner, 2005; Gond et al., 2011). While the relationship between management control systems and strategy has widely been investigated in the traditional accounting and control literature (e.g. Simons, 1990; Langfield-Smith, 1997; Ferreira and Otley, 2009; Tucker et al., 2009), this is much less frequent in the context of research related to the concept of sustainability. Indeed, until recently social and environmental accounting research has predominantly paid attention to external reporting and accountability (e.g. Albelda, 2011; Gray, 2002) or the link between corporate social responsibility/environmental management and economic performance (e.g. Henri and Journeault, 2010). Conscious of this situation, several researchers have stressed the need for research on the interrelation between sustainability, strategy and control (Parker, 2000; Chung and Parker, 2008; Durden, 2008) and a growing body of literature has emerged over the last years. We hope that in reviewing and reflecting on how this emerging body of literature is organised we can contribute to a better understanding of our current knowledge and to the development of new knowledge in the future. The paper thus also aims to suggest future directions for research. Our interest in reviewing and codifying the literature is also driven by a practical need to further embed sustainability into organisations. Until today, it seems that many organisations are still confronted with difficulties in “operationalising” sustainability and translating their strategic aspirations for sustainability into practice in the midst of many other business pressures (Epstein and Roy, 2001; Schaltegger and Wagner, 2006; Taplin et al., 2006; CIMA and Accenture, 2011). [less ▲]

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See detailStudy  of  breast  cancer  adaptation  to  anti-­angiogenic  therapies  by   molecular  imaging  on  tissue  slides
Cimino, Jonathan ULg; Calligaris, David ULg; Debois, Delphine ULg et al

Conference (2012, September 04)

Breast   carcinoma   is   the   most   common   and   second   leading   cause   of   cancer   mortality   in   women1.   The   ␣␣␣␣␣␣␣␣␣␣␣␣ ␣␣␣ ␣␣␣␣ ␣␣␣␣␣␣␣␣␣␣␣␣ ␣␣␣␣␣␣␣␣ ␣␣␣ ␣␣ ␣␣␣␣-­‐limiting   ... [more ▼]

Breast   carcinoma   is   the   most   common   and   second   leading   cause   of   cancer   mortality   in   women1.   The   ␣␣␣␣␣␣␣␣␣␣␣␣ ␣␣␣ ␣␣␣␣ ␣␣␣␣␣␣␣␣␣␣␣␣ ␣␣␣␣␣␣␣␣ ␣␣␣ ␣␣ ␣␣␣␣-­‐limiting   secondary   step   in   tumorigenesis   led   to   extensive   pre-­‐clinical   researches   on   angiogenesis   and   finally   the   approval   of   VEGF-­‐neutralizing   antibodies   (bevacizumab)  and  VEGF  receptor  tyrosine  kinase  inhibitors  (RTKs:sunitinib).  The  Sunitinib  has  been  used   clinically   in   patients   with   breast   cancer   refractory   to   other   therapeutic   agents2.   Unfortunately,   like   the   cytotoxic   therapies,   these   drugs   do   not   produce   lasting   effects   and   resistance   to   treatment   appeared   clinically3.   Recently,   independent   laboratories   have   reported   experimental   data   demonstrating   that   anti-­‐ angiogenic   treatments   inhibit   tumor   growth,   but   also   stimulate   the   formation   of   lung   metastases   after   treatment   discontinuation4.   The   field   of   imaging   mass   spectrometry   provides   new   tools   to   visualize   and   study  the  profiles  of  proteins  and  small  molecules  associated  with  biomedical  problems5.   To  this  aim,  we  conducted  a  series  of  experiments  to  setup  a  reproductible  model  of  resistance  to  sunitinib.   The   cells   MDA-­‐MB-­‐231   triple   negative,   from   human   breast   cancer   and   expressing   luciferase   are   injected   subcutaneously  into  mice  RAG1-­‐/-­‐.  The  mice  were  divided  into  four  experimental  groups  including,  on  the   one  hand,  control  mice  treated  with  placebo  (Carboxymethyl  cellulose,  CMC)  sacrificed  on  day  30  (group  1)   or  when  the  tumor  reached  a  volume  of  300  mm3  (group  2).    On  the  other  hand,  Sunitinib-­‐treated  mice  (LC   Laboratories,   40mg/kg/day),   sacrificed   at   day   30   (group   3),   or   when   the   tumor   reached   a   volume   of   300   mm3  (group  4).  MALDI  mass  spectrometry  imaging  was  performed  on  tissue  sections  of  tumors  and  organs   subsequently   colonized   by   metastases.   Matrix   sublimation   was   used   to   coat   tumor   sections   (14   μm-­‐tick)   with   1.5   Diaminonaphthalene   (1.5   DAN)   for   lipids   analysis   and   Sinapinic   acid   (SA)   for   entire   proteins   analysis.   Ion   cartographies   were   recorded   with   a   Solarix9.4T   FTMS   instrument   for   lipids   and   with   an   Ultraflex   II   TOF-­‐TOF   instrument   for   entire   proteins   (BrukerDaltonics,   Bremen,   Germany)   with   a   spatial   resolution  of  100  μm.     The  analysis  of  differential  protein/lipid  profiles  with  high  mass  accuracy  and  broadband  resolution  allows   detection   of   intense   signals   from   lipid   families   such   as   Phosphatidylcholine   (PC),   Triglyceride   (TAG),   Sphingomyelin   (SM)   and   precise   lipid   droplets   or   tumor   cells   differentiated   location   in   the   Sunitinib   resistant   tumor   cells   compared   to   control   cells.The   protein   profiles   of   the   4   groups   of   mice   show   differences   in   intensity   and   location,   enabling   a   correlation   to   inflammatory   (highlighted   by   histological   staining)  and  angiogenic  phenomenon.   [less ▲]

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See detailFactors influencing wild boar presence in agricultural landscape: a habitat suitability modelling approach
Morelle, Kevin ULg; Lejeune, Philippe ULg

Conference (2012, September 04)

The wild boar (Sus scrofa L.) population has increased in most parts of Europe during the last three decades. As a consequence, population distribution ranges have shifted to more agricultural areas ... [more ▼]

The wild boar (Sus scrofa L.) population has increased in most parts of Europe during the last three decades. As a consequence, population distribution ranges have shifted to more agricultural areas. These newly colonized areas are characterized by highly fragmented forest cover and a preponderance of crop fields and grasslands, thus increasing the risk of problematic interactions with farming activities and small game species. Although plasticity of wild boar to various environmental conditions is well known, understanding the ecological patterns that promote the density distribution of the species within agricultural areas remains of importance for adapted management strategies within these landscapes. Inside a recently occupied area (between 10-30 years of wild boar regular presence) of southern Belgium, we studied the relation between occurences of wild boar population, estimated by hunting bag and crop damages, with a set of environmental, anthropic and landscape variables. We used Maximum Entropy (MaxEnt) approach to analyze the data. Considering the main factors known to favour wild boar distribution, we hypothesized that crop fields providing cover and food, deciduous forest (providing mast) and water stream density are the main factors influencing the wild boar density distribution. The results are used to derive a habitat suitability map of wild boar distribution in northern Wallonia where wild boar recently starts to spread. [less ▲]

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See detailEsthétique du symptôme et politique de l’imagination
Hagelstein, Maud ULg

Conference (2012, September 04)

Cette intervention se propose de retracer les moments décisifs de la construction de la théorie de l’image didi-hubermanienne. Celle-ci se décline en deux temps (esthétique du symptôme / politique de ... [more ▼]

Cette intervention se propose de retracer les moments décisifs de la construction de la théorie de l’image didi-hubermanienne. Celle-ci se décline en deux temps (esthétique du symptôme / politique de l’image), jalonnés de rencontres avec des auteurs dont l’influence est manifeste (Panofsky, Freud, Warburg, Benjamin). En automne 2006, la revue Vacarme (n°37) proposait à ses lecteurs un entretien avec Georges Didi-Huberman (mené par Pierre Zaoui et Mathieu Potte-Bonneville). Au milieu de l’entretien, surgit la demande suivante : « Permettez-moi de vous poser la question un peu brutalement : quel est votre rapport réel à la politique ? […] Il semble que vous entreteniez un rapport extrêmement subtil, mais du même coup peu lisible au premier coup d’œil, à la chose publique et à la question des rapports sociaux en général. […] Il semble que vous vous arrêtiez toujours aux frontières de l’engagement, à la fois pour des motifs à la Foucault – ne pas s’emparer de la parole et de l’image de ceux qui souffrent ou agissent – et pour des motifs plus "indicibles" ». La réponse de Didi-Huberman n’est pas – à cet endroit du moins – bouleversante d’originalité : il faut bien dit-il reconnaître sa limite sur certains dossiers de l’actualité – s’engager à tout va, sans connaître les problèmes de première main, ne servirait à rien. Il admet : de nature contemplative, le rapport aux images semble d’abord coupé de l’action. Mais par ailleurs, le théoricien de l’image ne peut se résoudre à la fascination d’un monde visuel replié sur lui-même. Il faut bien qu’il sorte du musée, de la bibliothèque, de l’atelier d’artiste, pour plonger au cœur du réel et se contraindre à affronter ses aspects les plus inquiétants. Mettre les images au contact du réel, voilà la tâche la plus difficile : « L’inquiétude du contact entre l’image et le réel n’est autre qu’une accession à la dimension politique des images » . Depuis cet entretien, Didi-Huberman a développé une « politique de l’image » plus explicite, avec deux ouvrages en 2009 : Quand les images prennent position (premier volume d’un cycle intitulé L’œil de l’histoire – en trois volumes désormais tous publiés) et Survivance des lucioles (autour de Paolini). À nouveau marqué par le souffle critique de Walter Benjamin, ce dernier texte permet à son auteur de se situer très clairement dans le champ de la réflexion politique sur l’image – en prenant, surtout, ses distances à l’égard de la pensée « apocalyptique » de Giorgio Agamben. Tel est bien l’argument décisif de Survivance des lucioles : face au constat tragique du « dépérissement culturel » de nos sociétés actuelles, deux attitudes sont possibles. Soit on souligne le pire, en reprochant aux images leur pacte secret avec le pouvoir aliénant, et on prend le ton défaitiste du chroniqueur de la fin des temps, attendant désespérément une rédemption venue d’on ne sait où. Soit on souligne les efforts de résistance, les lueurs du contre-pouvoir et la « capacité de suspension, de transformation, de bifurcation » de l’image s’insérant dans la sphère politique. Mais on ne peut pas parler pour autant d’un « tournant politique » de l’esthétique didi-hubermanienne, tant les thèmes aujourd’hui avancés dans les ouvrages récents font écho aux premières interventions. Le débat épistémologique entamé très tôt avec les maîtres à penser de l’histoire de l’art traditionnelle montrait déjà à quel point les opérations théoriques relatives aux images (décrire, interpréter, analyser, retracer l’histoire) sont lourdes de conséquences d’un point de vue idéologique. Je voudrais faire voir la continuité très nette que l’on peut établir entre l’esthétique du symptôme et la politique de l’image. [less ▲]

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See detailAnalysis of the Biocompatibility of Different Intraocular Lens (IOL) Material Using Mass Spectrometry Tisssue Imaging
Bertrand, Virginie ULg; Debois, Delphine ULg; Calligaris, David ULg et al

Conference (2012, September 04)

The cataract corresponds to the total or partial opacification of the lens of the eye preventing the passage of the light. At present, the surgery is the only effective treatment to overcome the cataract ... [more ▼]

The cataract corresponds to the total or partial opacification of the lens of the eye preventing the passage of the light. At present, the surgery is the only effective treatment to overcome the cataract. The surgical intervention consists in removing the cloudy lens and to replace it by an artificial intraocular lens (IOL). The in vivo implantation of these synthetic lenses involves the evaluation of several factors as their physico-chemical properties, their capacities to interact with lens epithelial cells and proteins, as well as their biocompatibility. During a previous study, we demonstrated major differences concerning the tackiness (atomic force microscopy), the cellular adhesion and the protein adsorption of various polymer disks intended for the manufacturing of intraocular lenses. The aim of this work was to correlate a histological analysis to a mass spectrometry imaging analysis performed on the same sample. To estimate the biocompatibility of the biomaterials, an animal testing was realized in rabbits. The various polymers were implanted subcutaneously. After one month, the 2 cm x 3 cm pieces of rabbit skin and underlying muscle with a 2 cm thickness were removed, fixed with formaldehyde 10% during six days, treated for the paraffin inclusion and stored at room temperature until use. Slices of 5 µm thickness were performed using a microtome. Paraffin was removed and tissue sections were washed in graded ethanol baths. The slices were then stained with the hematoxylin and eosin dyes. The analysis of stained sections showed different histo-morphological features according to the implanted polymer. For MALDI MSI purposes, on tissue protein digestion was performed using trypsin (1) and the MALDI matrix (α-cyanohydroxycinnamic acid, 5 mg/mL in ACN/0.2% TFA 70:30) was deposited using an ImagePrep automated sprayer (Bruker Daltonics, Bremen, Germany). Experiments were carried out using an UltraFlex II TOF/TOF mass spectrometer (Bruker Daltonics, Bremen, Germany). MALDI imaging can show the detection of different proteomic profiles according to the tested biomaterials, which may be considered as biocompatibility markers. The MALDI images of these markers are then correlated with the histo-morphological profiles. Consequently, mass spectrometry imaging can become a powerful tool in the evaluation of the biocompatibility of artificial implants in biomedical application. [less ▲]

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See detailL’Action ou l’Espace : aux Prémices du Processus de la Conception Architecturale
Allani, Zeineb ULg

Conference (2012, September 04)

L’architecte, en tant que concepteur d’espaces, est confronté à un dilemme majeur, lors de la conception architecturale sera-t-il amené à privilégier l’image que donnera son projet en tant que forme ... [more ▼]

L’architecte, en tant que concepteur d’espaces, est confronté à un dilemme majeur, lors de la conception architecturale sera-t-il amené à privilégier l’image que donnera son projet en tant que forme matérielle perçue visuellement afin d’offrir au regard une oeuvre architecturale, parfois même sculpturale, ou bien doit-il sacrifier l’aspect au dépend de l’utilisation de l’espace par l’usager (le confort, l’habitude, la culture, …) ? [less ▲]

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See detailMetagenomic analysis as a tool to better characterize the bacterial content of food and food preparations.
Taminiau, Bernard ULg; Delhalle, Laurent ULg; Nezer, Carine et al

Conference (2012, September 04)

Metagenomic analysis is a new culture-independent approach for assigning a taxonomic, genic or functional identity to bacterial DNA fragments of unknown origin. Its power and utility is increasingly ... [more ▼]

Metagenomic analysis is a new culture-independent approach for assigning a taxonomic, genic or functional identity to bacterial DNA fragments of unknown origin. Its power and utility is increasingly rising thanks to the next generation sequencing techniques. It is now mature and cheap enough to be transposed to more applied fields like the food microbiology. We demonstrated in several studies the extraordinary potential of the targeted metagenomic analysis to different problematics related to food products. First, this approach is highly useful for the validation of the shelf life of food products. We analyzed standardized pork minced meat and meat product samples packaged either under modified atmosphere (MAP - 30% CO2, 70% O2) or under permeable atmosphere packaging, stored at different temperature (4°C, 4-8°C and 12°C) until the end of shelf-life. The metagenomic analysis allowed to identify species of all the sub-dominant bacterial populations. This approach showed why MAP can improve meat quality by favoring certain species rather than others. As a second example, we sought to identify the potential spoiling bacteria in several food products like raw fish, rind cheese or vacuum packed beef meats in order to illustrate the usefulness of metagenomics for the quality control of food preparations. Samples from various food matrices were screened to identify the bacterial contaminants. We combined the bioinformatics analysis with a classical approach to generate effective quantitative data for the various bacterial populations detected. This analysis characterizes the samples both on the identity of the potential spoiling bacteria present and on the quantification level of the contaminants. Finally, the metagenomic analysis reveals the presence of numerous uncultured and uncharacterized bacteria. The use of a carefully designed analysis pipeline has been used to ensure to label the bacterial population with a precise taxonomic identity and to determine whether the targeted population corresponds to a known species or not. This way, even if the nearest known homologous sequence is an environmental sample, its relatedness to known species can be deduced. This represents a new tool to trace yet uncharacterized food spoiling bacteria. [less ▲]

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See detailOrganometallic-mediated radical polymerization of vinyl amides: Effect of metal coordination
Kermagoret, Anthony ULg; Morin, A.; Hurtgen, Marie ULg et al

Conference (2012, September 04)

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See detailBiodegradable microcarriers based on chitosan and polyesters for tissue engineering
Demina, T; Akopova, T; Sevrin, Chantal ULg et al

Conference (2012, September 03)

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See detailAutomated Mineral Mapping in Optical Ore Microscopy : accuracy and limitations
Pirard, Eric ULg

Conference (2012, September 03)

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See detailThe structural complexity of phosphates in the Li-Fe2+-Fe3+ (+ PO4) system
Dal Bo, Fabrice ULg; Hatert, Frédéric ULg

Conference (2012, September 03)

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See detailThe Museum of Modern Art in Brussels: how 20 years of urban activism can fail
Houbart, Claudine ULg

Conference (2012, September 01)

The debate around the construction of the Museum of Modern Art in Brussels in the 1960’s and 70’s is the most revealing illustration of the urban struggle between « the ancients and the moderns”, in which ... [more ▼]

The debate around the construction of the Museum of Modern Art in Brussels in the 1960’s and 70’s is the most revealing illustration of the urban struggle between « the ancients and the moderns”, in which the associations play a crucial part besides the public authorities. From the beginning of the 1960’s, the implantation of the new building is the subject of numerous discussions where the “Ligue Esthétique”, a very conservative association proceeding from the Social Christian Party, founded in 1953, conflicts with the modernist designs of the Minister of Culture Pierre Wigny. Supporting the idea that the container should reflect the content, the Minister appoints the young architect Roger Bastin, whose project is also supported by the museum curator Philippe Roberts-Jones and the association “Les Amis des Musées”, lead by Count René Boël and comprising art patrons and lovers. Situated in a very delicate area of the city, besides the 18th century Place Royale and the Palace of Charles de Lorraine, the project plans the demolition of a historical building block occupied by dwellings and shops, and its replacement by a sculptural concrete building indicating the presence of the museum, almost entirely subterranean. This option earns the project the opposition of two more associations, which arise at the end of the 1960’s with very different backgrounds and aims. The “Quartier des Arts”, composed of members of the industrial aristocracy, politicians and public authorities representatives, is founded in 1967 with the aim of preserving the heritage of the area. Advised by the archaeologist and conservation expert Raymond Lemaire, the association is opposed to the demolition of one of the last ancient districts of Brussels. The ARAU (Atelier de recherche et d’action urbaine), founded in 1969 by the left wing sociologist René Schoonbrodt, fights for the maintain of the housing function of the city centre. The joint action of these very different groups of interest leads to a new version of the project and the giving up of the concrete signal building. But due to the length of the debates, more than a half of the ancient buildings have to be demolished and the other are very strongly restored: neither contemporary architecture, nor ancient heritage has won this urban battle. If the result of this long story seems today very disappointing as to urban design, the study of its mechanism is, on the other hand, particularly interesting: it reveals, through archival research, the complex relations between public and associative actors, where ideological and political considerations mix with personal – or even familial – relations and the hazards of urban life. [less ▲]

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See detailCognitive Mediation and hyper-reflexivity: Analyzing a “non-valid” Rorschach protocol of a schizophrenic patient
Englebert, Jérôme ULg

Conference (2012, September 01)

Nous proposons de réaliser une analyse du Rorschach d’un sujet schizophrène en phase de stabilisation. Le protocole ne répond pas aux critères de validité (moins de 14 réponses et refus de planche à 3 ... [more ▼]

Nous proposons de réaliser une analyse du Rorschach d’un sujet schizophrène en phase de stabilisation. Le protocole ne répond pas aux critères de validité (moins de 14 réponses et refus de planche à 3 reprises) et ne permet donc pas de réaliser une analyse structurale complète selon les recommandations du Système Intégré. Cependant, une étude que nous qualifierons de « phénoménologique » se révèle intéressante. En centrant notre réflexion sur le processus de médiation cognitive, que le sujet emploie de manière idiosyncrasique lorsqu’il est confronté à la consigne du test, nous observerons que la démarche implicite de « fausse perception » qui est suggérée au sujet (« qu’est-ce que cela pourrait-être ? ») semble difficilement tolérable. La principale particularité de ce protocole consiste en une remise en question par le sujet des éléments perçus, pour finir, la plupart du temps, par rejeter la réponse fournie. Le recours à ce « doute méthodique » est superposable à ce que les théorisations modernes de la psychopathologie phénoménologique appellent l’« hyper-réflexivité schizophrénique » (Sass, 1992, 1994, 2001 ; Stanghellini, 2006). Nous pouvons également réaliser un rapprochement entre ce processus perceptif et les théories du « salience syndrome » développées par la neuropsychologie sociale (Van Os, 2009 ; Van Os & Kapur, 2009). Ces considérations nous permettent de rediscuter la pertinence de la remédiation cognitive basée sur la connaissance de la maladie et la reconnaissance des symptômes associés à laquelle a été soumis le patient. L’analyse du Rorschach nous donne également des informations intéressantes sur la stabilisation symptomatologique de notre patient et sur la composante résiduelle de son trouble schizophrénique. Ces observations semblent incompatibles avec des hypothèses homéostatiques et la possibilité d’un retour à un état antérieur à la schizophrénie, et démontrent l’utilité du diagnostic de schizophrénie résiduelle. Enfin, cette présentation cherchera à construire des ponts entre la méthode du Système Intégré et la psychopathologie phénoménologique moderne. [less ▲]

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See detailStrategic bypass deterrence
Bloch, Francis; Gautier, Axel ULg

Conference (2012, September)

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See detailThe Uranus System Explorer (USE) – Unveiling the evolution and formation of icy giants
Costa, Marc; Nordheim, Tom; Provinciali, Lorenzo et al

Conference (2012, September)

The results presented are the output of a student exercise carried out at the Alpbach Summer School 2012 , the topic of which pertained to the exploration of the giant planets and their systems. In this ... [more ▼]

The results presented are the output of a student exercise carried out at the Alpbach Summer School 2012 , the topic of which pertained to the exploration of the giant planets and their systems. In this context, we propose in this paper the Uranus System Explorer (USE), a mission to investigate the Uranus planetary system and gain new insight into the formation and evolution of icy giants. [less ▲]

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See detailSuccessions internationales - panorama des difficultés dans les relations belgo-allemandes
Wautelet, Patrick ULg

Conference (2012, September)

Cette présentation fait le point sur les difficultés que présent le cadre juridique en vigueur actuellement dans les relations belgo-allemandes en matière successorale, pour mieux illustrer l'impact qu ... [more ▼]

Cette présentation fait le point sur les difficultés que présent le cadre juridique en vigueur actuellement dans les relations belgo-allemandes en matière successorale, pour mieux illustrer l'impact qu'aura le Règlement succession dont l'entrée en vigueur est prévue en 2015. [less ▲]

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See detailDistribution and identification of molecular interactions between tomato roots and bacterial biofilms
Debois, Delphine ULg; Jourdan, Emmanuel ULg; Smargiasso, Nicolas ULg et al

Conference (2012, September)

Some non pathogenic microorganisms evolving in the root micro-environment can trigger a positive effect on plant, increasing host defense against disease or/and directly inhibiting growth of pathogen in ... [more ▼]

Some non pathogenic microorganisms evolving in the root micro-environment can trigger a positive effect on plant, increasing host defense against disease or/and directly inhibiting growth of pathogen in soil (1). To initiate both phenomena leading to biocontrol activity, microorganisms use plant exudates to grow on roots and to produce in-situ active compounds. In Bacilli, cyclic lipopeptides of the surfactin, iturin and fengycin families represent important antibiotics involved in biocontrol (2). Recent studies in microbiology allowed a better understanding of plant microorganism interactions but few has been done at the molecular level. In this study, MALDI MS imaging has been used to study the nature of the secreted lipopeptide molecules, their relative quantity and their distribution in the root’s environment. Disinfected tomato seeds were first germinated at 28°C in sterile conditions for germination. Seedlings were then placed in Petri dish on ITO glass slide recovered with a thin layer of plant nutritive solution (Hoagland) containing 1,75% of agar and treated with freshly-grown cells of Bacillus amyloliquefaciens S499. Petri dishes were finally incubated vertically in phytotron at 28°C with a 16h photoperiod. Different root age / time of incubation were studied: 13 / 3; 13 / 7; 21 / 14 and 39 / 32. Control tomato root (without bacterial treatment) of the same ages were also analyzed (13 / 0; 21 / 0 and 42 / 0. For MALDI imaging experiments, the ITO slide was removed from the agar and dried in a dessiccator under vacuum. The matrix solution (α-cyano-hydroxycinnamic acid, 5mg/mL in ACN/0.2% TFA 70/30) was applied with an ImagePrep automated sprayer (Bruker Daltonics). An UltraFlex II TOF/TOF and a Solarix FT-ICR mass spectrometers were used to record molecular cartographies. The average mass spectra recorded around the tomato root (2-3 mm on both sides of the root) showed that lipopeptides were major compounds detected on the agar. The relative intensity of lipopeptides families varied with respect to the age of the root/biofilm system. In the 13/3 system, 3 homologues of surfactins were essentially detected (C13, C14 and C15), with very few iturins and fengycins. Their localizations were identical, whatever the considered homologue. Then the production of iturin and fengycin families increases in older systems (13/7 and 21/14) and a novel homologue of surfactin is detected (C12). Some variations in localizations within families may be observed (around the root or at the close vicinity of it in function of the considered homologue or alkali adduct). Then for the oldest system we studied, iturins and fengycins are not detected anymore and the localization of surfactins is less precise. In the 39/32 system, we also detected unknown compounds at 986.6, 1000.6, 1014.7 and 1028.7 m/z. The mass range of these compounds allied to the mass difference between two consecutive ion peaks let us think that these unknown compounds could be a new lipopeptide family. Investigations are in progress to identify these new secondary metabolites of Bacillus amyloliquefaciens. [less ▲]

Detailed reference viewed: 64 (12 ULg)
See detailMesozoic marine reptile palaeobiogeography in response to drifting plates
Bardet, Nathalie; Fischer, Valentin ULg; Houssaye, Alexandra et al

Conference (2012, September)

Mesosaurus Broom, 1913, from the Early Permian, is the first aquatic reptile known in the fossil record. Its co-occurrence in both South Africa (South Africa) and South America (Brazil, Uruguay) made it ... [more ▼]

Mesosaurus Broom, 1913, from the Early Permian, is the first aquatic reptile known in the fossil record. Its co-occurrence in both South Africa (South Africa) and South America (Brazil, Uruguay) made it one of the key-fossils - with the pteridospermatophyta plant Glossopteris - used by the German meteorologist / geophysician Alfred Wegener to support his theory of the Continental Drift (Kontinentalverschiebung), first published in 1912. But Mesosaurus was only the “tip of the iceberg” as, during the Mesozoic, various clades of reptiles massively invaded the aquatic, and more especially, the marine realm. They were highly diversified both systematically and ecologically, and some of them were large top-predators of the marine ecosystems. The main groups were, in order of appearance in the fossil record, Ichthyosauria (earliest Triassic – early Late Cretaceous), Sauropterygia (nothosaurs, pachypleurosaurs, placodonts, plesiosaurs; Early Triassic – latest Cretaceous), Thalattosauria (Middle-Late Triassic), Pleurosauria (Early Jurassic–Early Cretaceous), as well as, among others, several lineages of Chelonians (e.g. chelonioids, bothremydids, “thalassemyds”), Crocodyliformes (thalattosuchians, dyrosaurids, pholidosaurids, gavialoids) and Squamates (mosasauroids, “dolichosaurs”, marine snakes). During the Mesozoic, the palaeobiogeographical distributions and the dispersion events of these marine reptiles closely followed the break-off of the Pangea induced by plate tectonic movements. Although marine reptiles can help in determining the possible date of opening of marine corridors, the information they provide are less precise than that delivered by terrestrial faunas, as the marine realm is a more open system and various migration ways are always possible. Generally, the Triassic taxa were animals with a restricted palaeobiogeographical distribution living near the coastlines of the Pangea. From the end of the Triassic and during the Jurassic, the break-off of the Pangea resulted in the formation of large marine corridors, allowing open-sea marine reptiles such as ichthyosaurs, plesiosaurs and crocodyliformes to spread out over large distances. As an example, similar marine reptile faunas are known from the Jurassic of Europe and southern South America, as a result of dispersion events via the Hispanic Corridor that connected the Tethys / North Atlantic and Pacific realms at this time. During the Cretaceous, and notably with the expansion of the Atlantic Ocean, most of these reptiles were cosmopolite and open-sea forms (plesiosaurs, mosasaurid squamates, chelonioid turtles). However, even if large faunal interchanges were possible, some provinces such as the Northern and Southern margins of the Tethys were characterized by a peculiar faunal identity, notably concerning mosasaurids, despite the apparent absence of barriers. So, if Continental Drift enabled circulation and faunal interchanges, other parameters such as ecological constraints probably also played a role in the distribution of these marine reptile faunas. [less ▲]

Detailed reference viewed: 164 (2 ULg)
See detailComment créer ou maintenir la motivation des étudiants en Haute Ecole ?
Poumay, Marianne ULg

Conference (2012, September)

Detailed reference viewed: 52 (9 ULg)
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See detailProceedings of the 12th Nordic Steel Construction Conference
Li, Yongzhen; Rossi, Barbara ULg

Conference (2012, September)

Detailed reference viewed: 155 (4 ULg)
See detailQuelle qualité de l'enseignement en ligne et quels partages possibles ?
Poumay, Marianne ULg

Conference (2012, September)

Ce forum a pour objectif de présenter les technologies de demain qui permettront aux hommes de mieux vivre ensemble dans les domaines de la santé, des transports, de la culture, de l'éducation et de l ... [more ▼]

Ce forum a pour objectif de présenter les technologies de demain qui permettront aux hommes de mieux vivre ensemble dans les domaines de la santé, des transports, de la culture, de l'éducation et de l'environnement. [less ▲]

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See detailConstant 2-labelling of a graph
Gravier, Sylvain; Vandomme, Elise ULg

Conference (2012, September)

We introduce the concept of constant 2-labelling of a weighted graph and show how it can be used to obtain periodic sphere packing. Roughly speaking, a constant 2-labelling of a weighted graph is a 2 ... [more ▼]

We introduce the concept of constant 2-labelling of a weighted graph and show how it can be used to obtain periodic sphere packing. Roughly speaking, a constant 2-labelling of a weighted graph is a 2-coloring (black and white) of its vertex set which preserves the sum of the weight of black vertices under some automorphisms. In this manuscript, we study this problem on weighted complete graphs and on weighted cycles. Our results on cycles allow us to determine (r,a,b)-codes in Z^2 whenever |a-b|>4 and r>1. [less ▲]

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See detailCestodes and Acanthocephalans parasitizing small mammals from Benin
Houemenou, Gualbert; Martin-Alonso, A.; Sanchez, S. et al

Conference (2012, September)

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See detailZelfbehandeling van frequente hoofdpijn : een Belgische apotheekstudie
Mehuys, E; Paemeleire, K; Van Hees, Thierry ULg et al

Conference (2012, September)

Detailed reference viewed: 25 (16 ULg)
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See detailLight as a modulator of cognitive brain functions
Vandewalle, Gilles ULg

Conference (2012, September)

Detailed reference viewed: 23 (2 ULg)
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See detailAn attempt to date by OSL the implantation of megaliths : the case of the standing stones of Le Gâvre (France)
Blain, Sophie ULg; Guibert, Pierre; Cassen, Serge et al

Conference (2012, September)

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See detailTowards an integrative model of short-term memory : the A-O-STM framework.
Majerus, Steve ULg

Conference (2012, September)

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See detailWaste management evolution through years: evaluation of improvement using Life Cycle Assessment methodology
Belboom, Sandra ULg; Renzoni, Roberto ULg; Digneffe, Jean-Marc et al

Conference (2012, September)

Waste is considered as a major concern of our century. New technologies and attempts to improve appeared through years. The goal of this study was to evaluate the improvement of waste management through ... [more ▼]

Waste is considered as a major concern of our century. New technologies and attempts to improve appeared through years. The goal of this study was to evaluate the improvement of waste management through the last forty years. Four steps of time and of technologies of waste treatment were evaluated in an environmental point of view using the life cycle assessment methodology. The first scenario is situated before 1970 with waste landfilling in an open dump without recuperation and valorization of gas. The second one considers the situation between 1990 and 2008 with a plant comprising grinding and sorting of waste to obtain refused derived fuel fraction (RDF) which was burnt in an incinerator, remaining waste being sent to sanitary landfill with recuperation and valorization of gas in electricity. The third one is the current one, in operation since 2009, with incineration of the whole of the residual municipal waste. The last scenario is about future considering the current installation and adding a biomethanation plant using the collected biodegradable fraction of household waste. This environmental evaluation was performed in accordance with the ISO standards 14040 and 14044 and the environmental impacts were calculated with the ReCiPe methodology. We modeled a specific plant situated in Liege using its technical and environmental reports to be as realistic as possible. Main result of this study is the improvement through years starting from the important environmental impact for the landfilling of waste in an open dump to an environmental gain for some categories with the current installation coupled with biomethanation. Global warming impact from the eighties was reduced by 9 in the years 1990-2008 and by 14 for the current scenario alone or coupled with a biomethanation plant. Some sensitivity analyses were used to evaluate the strength of assumptions with for example using a consequential LCA instead of an attributional one and modifying the electricity origin mix. An uncertainty analysis using Monte-Carlo method showed the robustness of our results. This study confirms the environmental improvement of technologies and emissions of waste management through years. [less ▲]

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See detailHepatitis E virus infection in domestic swine, wild boar and human in Belgium
Thiry, Damien ULg; Mauroy, Axel ULg; Brochier, Bernard et al

Conference (2012, September)

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See detailHow does engagement in reading predict digital reading proficiency among 15 year-olds?
Lafontaine, Dominique ULg; Monseur, Christian ULg; Baye, Ariane ULg

Conference (2012, September)

In PISA 2009, 19 countries took part to an optional assessment of digital reading. In each country, a subsample of 15 year-olds was administered not only the paper and pencil PISA test, but also different ... [more ▼]

In PISA 2009, 19 countries took part to an optional assessment of digital reading. In each country, a subsample of 15 year-olds was administered not only the paper and pencil PISA test, but also different reading tasks online. The aim of our study is to investigate the relationships between engagement in reading, especially online reading practices, and digital reading proficiency of 15 year-olds in the 11 European countries which took part to this option (11 out of 19). [less ▲]

Detailed reference viewed: 78 (6 ULg)
See detailOntogenesis of kisspeptin neurons: from neurogenesis to adulthood
Desroziers, Elodie ULg; Droguerre, Marine; Bentsen, A.H et al

Conference (2012, September)

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See detailLes carrières professionnelles des cadres : regard croisé du genre et de l'âge
Grodent, Françoise ULg; Cornet, Annie ULg

Conference (2012, September)

Ce papier a pour objectif de réaliser une revue de littérature qui doit permettre de construire une recherche empirique visant à apporter une vision comparative des carrières des hommes et des femmes ... [more ▼]

Ce papier a pour objectif de réaliser une revue de littérature qui doit permettre de construire une recherche empirique visant à apporter une vision comparative des carrières des hommes et des femmes cadres en regard de trois groupes d’âge : les moins de 35 ans, les [35-50] ans et les plus de 50 ans. Nous considérons les deux sexes étant donné que les trajectoires professionnelles sont influencées par le sexe de la personne ainsi que par les stéréotypes et les rôles qui y sont directement associés (genre). Les générations, quant à elles, nous permettront de tenir compte de l’évolution des facteurs de contexte que sont notamment ces rôles attribués au masculin et au féminin à travers les époques. En effet, les constructions sociales liées au sexe des individus sont susceptibles de changer d’une génération à l’autre et donc d’agir distinctement sur les intentions de carrière. Le fait d’introduire la dimension générationnelle, en plus de celle du genre, est l’occasion d’aborder le concept d’intersectionnalité qui consiste en un croisement des groupes cibles propres à la gestion de la diversité. A l’issue de cet aperçu théorique faisant état de la littérature existante relative à cette thématique des carrières des individus occupant un poste à responsabilités, nous pourrons mettre en évidence différentes questions de recherche qu’il nous faudra, dans un second temps, confronter à la réalité du terrain. [less ▲]

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See detailThe OUFTI-1 nanosatellite system in mid-2012: architectures of ground and space segments
Denis, Amandine ULg; Pisane, Jonathan ULg; Crosset, Nicolas ULg et al

Conference (2012, September)

We describe the current status of the OUFTI-1 nanosatellite project, the main payload of which is an innovative D- STAR radiocommunication system. We describe the architectures of the ground and space ... [more ▼]

We describe the current status of the OUFTI-1 nanosatellite project, the main payload of which is an innovative D- STAR radiocommunication system. We describe the architectures of the ground and space segments. [less ▲]

Detailed reference viewed: 63 (21 ULg)
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See detailFusion alpha and proton diagnostics by thin layer activation
Chene, Grégoire ULg; Bonheure, George; Delhalle, René ULg et al

Conference (2012, September)

Detailed reference viewed: 29 (2 ULg)
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See detailQuand l’art parle des restructurations : au-delà du dévoilement, une forme d’expérimentation
Pichault, François ULg; Baujolin, Rachel; Schmidt, Géraldine et al

Conference (2012, September)

Detailed reference viewed: 57 (3 ULg)
See detailRevision of the Annex VI of the Regulation (EC) n° 152/2009
Lecrenier, Marie-Caroline ULg; Veys, Pascal; Berben, Gilbert et al

Conference (2012, September)

Detailed reference viewed: 12 (2 ULg)
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See detailSPICAM dayglow measurements: a tool to retrieve CO2 vertical density profile and exospheric temperatures
Stiepen, Arnaud ULg; Gérard, Jean-Claude ULg; Bougher, S. et al

Conference (2012, September)

We analyze the behavior of the CO2+ and CO Cameron ultraviolet dayglow in the atmosphere of Mars through a large dataset of dayside grazing limb observations performed by the Spectroscopy for ... [more ▼]

We analyze the behavior of the CO2+ and CO Cameron ultraviolet dayglow in the atmosphere of Mars through a large dataset of dayside grazing limb observations performed by the Spectroscopy for Investigation of Characteristics of the Atmosphere of Mars (SPICAM) on board the Mars Express spacecraft. Limb profiles are studied to retrieve the temperature of the Martian exosphere and its variability with season, latitude and solar activity. We use a one-dimensional chemical-diffusive model to retrieve the main features of the emissions and constrain the temperature and density vertical profiles of the main components of the Martian atmosphere. [less ▲]

Detailed reference viewed: 58 (4 ULg)
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See detailMANAGING PUBLIC ORDER DURING
Schoenaers, Frédéric ULg; Vincent, Jeffrey; Easton, Marleen et al

Conference (2012, September)

Detailed reference viewed: 40 (5 ULg)
See detailFunctional degradable polymers for advanced drug delivery systems
Cajot, Sébastien; Riva, Raphaël ULg; Jérôme, Christine ULg

Conference (2012, September)

Nowadays, polymer micelles have attracted an increasing interest in pharmaceutical research because they could be used as efficient drug delivery systems. Micelles of amphiphilic block copolymers are ... [more ▼]

Nowadays, polymer micelles have attracted an increasing interest in pharmaceutical research because they could be used as efficient drug delivery systems. Micelles of amphiphilic block copolymers are supramolecular core-shell type assemblies of several tens of nanometers in diameter. In principle, the micelle core is usually constructed with biodegradable hydrophobic polymers such as aliphatic polyesters, e.g. poly(ε-caprolactone) (PCL), which serves as a reservoir for the incorporation of various lipophilic drugs. Water soluble poly(ethylene oxide) (PEO) is most frequently used to build the micelle corona because it is very efficient in preventing protein adsorption at surfaces and in stabilizing micelles in the blood compartment, making particles invisible to the body defense system. Even if micelles get a high stability in aqueous media thanks to their low critical micellar concentration, micelle dissociation is not always preserved when they are injected in the blood compartment. A way to provide the micelle stability during their administration is to cross-link them. Different kinds of cross-linked micelles can be investigated depending on the localization of the cross-linking. Shell cross-linked micelles or nanocage structures with a degradable core have the great advantage to reach drug encapsulation with a high loading rate. However, cross-linking the hydrophilic shell may affect the stealthiness of the carrier. Thus, we have designed reversibly cross-linked micelles by introducing the cross-linking bridges in the hydrophobic segment of the block copolymer, rather than in the hydrophilic one, leading so to more internal cross-linking and thus preserving the mobility of the hydrophilic segment. Three different localizations of the cross-linking has been targeted; (i) loose core cross-linking of a core-corona system, (ii) tight core cross-linking of a core-shell-corona system (the shell and the core being both hydrophobic and the corona hydrophilic) and (iii) tight shell cross-linking of a similar core-shell-corona system. To reach this goal, three types of amphiphilic copolymers have been used bearing pendent azide groups in the hydrophobic segment. These copolymers have been obtained by starting the ring-opening polymerization of ε-CL and a functional CL, either as a mixture or sequentially from a poly(ethylene oxide) macroinitiator leading to the three targeted architectures. The azide groups located along the PCL backbone have then been used to cross-link the micelles by the Huisgens cycloaddition with a bis-alkyne cross-linker. The choice of this cross-linker has also taken into account the requirement to make the cross-linking reversible. For that purpose, disulfide bridges have been selected in order to impart reversibility to the cross-linking by intracellular reduction. Indeed, the marked concentration difference of glutathione between extra- and intra-cellular environments has already been used to trigger drug release by intracellular disulfide bond cleavage. Accordingly, a bis-alkyne disulfide molecule has been chosen as cross-linker. The micellization and cross-linking of these amphiphilic azido macromolecules have been studied. The reversibility of the cross-linking in reductive environment and the cross-linked micelles stealthiness have been tested. [less ▲]

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See detailPower line dynamic rating: forecasting potential period of low wind speed is crucial
Nguyen, Huu-Minh ULg; Doutreloup, Sébastien; Erpicum, Michel ULg et al

Conference (2012, September)

The replacement and building of new electrical power lines (50 000 km in Europe) can’t cope with the growth of RES development in EU for the ten upcoming years. New solutions have to be found to manage ... [more ▼]

The replacement and building of new electrical power lines (50 000 km in Europe) can’t cope with the growth of RES development in EU for the ten upcoming years. New solutions have to be found to manage such power transmission needs. Dynamic Line Rating (DLR) systems are part of the global solution. They allow to increase the power line capacity by an average 20% over the static rating (which is defined as the maximum current-carrying capacity as designed). The ampacity or thermal rating, is calculated thanks to (i) sensors installed directly on the power line conductors, like Ampacimon, (ii) weather data, and (iii) standard thermal models (IEEE, CIGRE). However, in order to be fully effective and to allow an efficient use of assets, ampacity calculation in real-time is not enough; it has to be forecasted as well. Beyond 6h-forecast, weather forecasts are necessary to compute the line ampacity up to two days ahead, as needed by network operation. As wind convection has a major impact on conductor cooling, even low wind speeds (2m/s up to 5m/s) allow a huge ampacity increase (the actual rating can be doubled). Therefore, low wind speed forecast up to 2-days ahead finds a major application in dynamic rating of overhead transmission and distribution lines. [less ▲]

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See detailPredictive models for strength enhancements in cold-formed structural sections
Rossi, Barbara ULg; Afshan, Sheida; Gardner, Leroy

Conference (2012, September)

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See detailIgE antibodies critically contribute to acquired enhanced resistance to honeybee venom in mice
Marichal, Thomas ULg; Starkl, Philipp; Reber, Laurent L. et al

Conference (2012, September)

Detailed reference viewed: 25 (0 ULg)
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See detailThe diversification of early eukaryotes
Javaux, Emmanuelle ULg

Conference (2012, September)

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See detailUNFOLDING SYNTHETIC PEPTIDES BY AFM AT THE SINGLE-MOLECULE LEVEL
Willet, Nicolas ULg; Hinterdorfer, Peter; lecommandoux, Sébastien et al

Conference (2012, September)

The aim of this study is to investigate the mechanochemical behavior of homopolypeptides able to change their conformation is a stimuli-responsive way. The peptidic secondary structures were studied in ... [more ▼]

The aim of this study is to investigate the mechanochemical behavior of homopolypeptides able to change their conformation is a stimuli-responsive way. The peptidic secondary structures were studied in detail by atomic force microscopy (AFM) at the single-molecule level. Synthetic copolymers containing a polypeptide block were prepared by N-carboxyanhydride amino acid ring-opening polymerization. The polymer chains were grafted as a dilute brush onto gold surfaces and their mechanochemical behavior was then studied by AFM single-molecule force spectroscopy (SMFS). The investigated polypeptide blocks were based on poly(L-glutamic acid), which undergoes a transition from alpha-helix to random coil. This can be induced by external stimuli (pH, ionic strength, temperature) or simply by applying a force. We were able to study the mechanically driven unfolding of the peptide by stretching-release cycles of the biomacromolecule. Stretching the helical peptide resulted in original features in the force-distance traces. Plateaus that are specific for the helical conformation were detected, quantified and discussed. Pulling-relaxing SMFS experiments will eventually lead to a better understanding of the force-induced unfolding of an alpha-helix and the reversibility of the phenomenon. [less ▲]

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See detailLes fondements économiques de la motivation des sanctions
Sibony, Anne-Lise ULg

Conference (2012, September)

Il existe une approche économique des sanctions. Les économistes proposent ainsi des théories ou des modèles de sanctions qui permettent de calculer la sanction optimale en fonction d'un certain nombre de ... [more ▼]

Il existe une approche économique des sanctions. Les économistes proposent ainsi des théories ou des modèles de sanctions qui permettent de calculer la sanction optimale en fonction d'un certain nombre de paramètres considérés comme pertinents. Cette contribution explore les possibilité pour les juridiction d'emprunter à ces approches économiques lorsqu'elles doivent imposer des sanctions et en motiver le quantum. [less ▲]

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See detailA severe drop in Eurasian ichthyosaur diversity prior to their late Cenomanian extinction: local or global signal?
Fischer, Valentin ULg

Conference (2012, September)

During the last decade, our knowledge of the taxonomic diversity of the Early Cretaceous ichthyosaurs (Mesozoic marine reptiles) has increased significantly, with the recognition of new species, genera ... [more ▼]

During the last decade, our knowledge of the taxonomic diversity of the Early Cretaceous ichthyosaurs (Mesozoic marine reptiles) has increased significantly, with the recognition of new species, genera, and subfamilies from Canada, Europe, and Russia. New data from England, France, and western Russia suggest ichthyosaurs remained diverse and abundant in western Eurasian marine ecosystems up to the late Albian–early Cenomanian, with the co-occurrence of three to four taxa occupying two to three distinct ecological niches in each formation considered (Cambridge Greensand Member, England; Marnes Bleues Formation, France; Stoïlensky quarry, Russia). However, the overlying formations (middle–late Cenomanian), consisting of chalk or glauconiferous sands, have yielded a very depauperate ichthyosaur fauna. These ichthyosaur assemblages are monospecific and comprise medium to large-sized, presumably opportunistic predators belonging the genus Platypterygius. This suggests a severe drop in ichthyosaur diversity some 5 millions years before their final extinction, which presumably occurred at or near the Cenomanian–Turonian boundary. However, it is difficult to know if this pattern is biased or genuine: the diversity drop may very well be an effect of preservational/ecological biases as well as a genuine extinction linked to the profound environmental changes occurring during the Cenomanian. The presence of similar impoverished assemblages in Cenomanian sediments worldwide favours the latter hypothesis, but the question remains open for now. [less ▲]

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See detailDermatosparaxis : altered processing of type I procollagen by ADAMTS2 and beyond.
Colige, Alain ULg

Conference (2012, September)

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See detailDeformation pattern at the western tip of the Corinth Rift
Beckers, Arnaud ULg; Hubert, Aurelia ULg; Beck, Christian et al

Conference (2012, September)

The Gulf of Corinth in Greece is an active continental rift propagating westward toward the Aegean subduction zone. GPS data shows that deformation rate reaches a maximum of 15 mm/yr at its western tip ... [more ▼]

The Gulf of Corinth in Greece is an active continental rift propagating westward toward the Aegean subduction zone. GPS data shows that deformation rate reaches a maximum of 15 mm/yr at its western tip. The style of extension and strain distribution is well documented offshore in the eastern and central parts of the rift (Bell, 2009). At its most active western extremity, published offshore data is not sufficient to characterize the deformation pattern. High resolution seismic profiles were thus acquired in that region within the framework of the SISCOR project to improve our understanding of fault evolution, seismicity and to be able to construct mechanical models of deformation. Here we investigate the spatio-temporal pattern of the basin subsidence and deposition with sparker data acquired in November 2011. Active faults and correlative time horizons were first mapped. The stratigraphy was then correlated with the eustatic sea-level curve. This sequence stratigraphic interpretation is possible because there are strong glacial-interglacial variations in the depositional environment. In fact lacustrine conditions prevail within the gulf during glacio-eustatic lowstands and are characterized by low amplitudes seismic facies. So synrift sediment isopachs over the last 12 000 and 130 000 yrs could be produced. The interpreted data allow us to: (1) compare deformation pattern at the western tip of the Gulf with the more mature central and eastern part of the Rift; (2) constrain the pattern and the timing of deformation as well as rates of faulting. Reference Bell, R. E., McNeill, L. C., Bull, J. M., Henstock, T. J., Collier, R. E. L., & Leeder, M. R., 2009. Fault architecture, basin structure and evolution of the Gulf of Corinth Rift, central Greece. Basin Research, 21(6), 824-855. doi:10.1111/j.1365-2117.2009.00401.x [less ▲]

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See detailDioxin Food Crises and New POPs: Challenges in Analyses
Focant, Jean-François ULg

Conference (2012, September)

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See detailEffectiveness of pharmaceutical care for patients with COPD (PHARMACOP) : A randomized controlled trial
Tommelein, E; Mehuys, E; Van Hees, Thierry ULg et al

Conference (2012, September)

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See detailThe role of disorder in the mechanical control of trabecular bone as a cellular solid structure
Ruffoni, Davide ULg; Maurer, Manfred; Weinkamer, Richard et al

Conference (2012, September)

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See detailVenus O2 night glow observations with VIRTSI/Venus Express
Migliorin, Alessandra; Piccioni, Giuseppe; Gérard, Jean-Claude ULg et al

Conference (2012, September)

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See detailLa perception de la pénibilité au travail dans les métiers du social
Dubois, Valérie ULg; Cornet, Annie ULg

Conference (2012, September)

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See detailUn projet de promotion de la santé mentale : des actions élaborées avec une association d'usagers, partenaire du projet
Fond-Harmant, Laurence; Pull, Charles; Lerebourg, Annick et al

Conference (2012, September)

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See detailReading the plant fossil record through taxonomic survivorship curves
Cascales - Miñana, Borja ULg; Cleal, Christopher J.

Conference (2012, September)

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See detailImaging Guided Proteomics Unveils Heterogeneity in Colorectal Carcinoma Liver Metastases – Implications for Targeted Therapies
Blomme, Arnaud ULg; Turtoi, Andrei ULg; Castronovo, Vincenzo ULg

Conference (2012, September)

Patients suffering from liver metastases are diagnosed late and have a poor outcome. Targeted therapies are promising treatment options, however the malignant lesions are heterogeneous in nature offering ... [more ▼]

Patients suffering from liver metastases are diagnosed late and have a poor outcome. Targeted therapies are promising treatment options, however the malignant lesions are heterogeneous in nature offering niches for cancer cells to survive and regrow. A rational strategy is needed to select targetable antigens that would overcome this intra-tumoral heterogeneity. MALDI-MS imaging is an emerging tool to study the distribution of biomolecules in tissue samples and is a good base for defining the regions of interest (ROI) that deserve further in-depth analysis. We employed MALDI-MS imaging of colorectal liver metastasis to identify ROI and guide the proteomic analysis for a more in-depth picture of modulated proteins. The focus was laid on cell membrane and extracellular proteins as these have enhanced potential to be used for targeted therapy and clinical imaging applications. Four defined ROI were further analyzed employing 2D-Nano-UPLC-MSe methodology. Over 1500 unique proteins were statistically divided into different patterns of expression, generating a quantitative picture of the proteome heterogeneity in liver metastases. The results offered insight into novel targets but also antigens against which the antibodies are already involved in cancer clinical trials. Following immunohistochemistry based validation experiments, certain proteins demonstrated the potential to homogeneously cover the metastatic lesion and become better targets. Two such antigens, LTBP2 and TGFBI were selected for in vivo functional/ tumor targeting studies in colorectal carcinoma animal model. Importantly, we were able to demonstrate the “targetable” nature of these antigens for homing antibodies injected i.v. Functionally, TGFBI showed an additional potential to target the tumor via it’s ability to affect migration and growth of cancer cells, hence taking the influence on the process of tumorigenesis. In conclusion, liver metastases display a significant heterogeneity in terms of targetable biomarkers and these findings should flow in the future development of targeted therapies aiming to cure the patient. [less ▲]

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See detailGrétry moraliste et mémorialiste
Daubercies, Laurence ULg

Conference (2012, September)

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See detailExemple d'un dispositif de formation basé sur l'accompagnement réflexif de la pratique : le CAPAES en langues modernes à l'ULg
Simons, Germain ULg

Conference (2012, August 31)

Après avoir brièvement décrit le contexte général du CAPAES en FWB, nous présentons le dispositif de formation en didactique professionnelle des langues modernes à l'ULg, en nous concentrant ... [more ▼]

Après avoir brièvement décrit le contexte général du CAPAES en FWB, nous présentons le dispositif de formation en didactique professionnelle des langues modernes à l'ULg, en nous concentrant principalement sur l'accompagnement individualisé des étudiants-enseignants assisté par la vidéo (autoscopie). Nous fournissons ensuite quelques éléments d'évaluation de ce dispositif de formation basés sur nos observations et sur deux types d'enquêtes (questionnaires et entretiens semi-structurés). Enfin, sur la base de cette évaluation croisée, nous proposons quelques pistes pour optimiser le dispositif actuel. [less ▲]

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See detailEvaluation sommaire du dispositif de formation initiale à l'ULg et pistes d'amélioration.
Simons, Germain ULg

Conference (2012, August 31)

Dans cette communication, nous présentons d'abord le dispositif de formation initiale des enseignants du secondaire supérieur dans la Fédération Wallonie-Bruxelles. Ensuite, nous épinglons quelques points ... [more ▼]

Dans cette communication, nous présentons d'abord le dispositif de formation initiale des enseignants du secondaire supérieur dans la Fédération Wallonie-Bruxelles. Ensuite, nous épinglons quelques points forts et problèmes liés à cette formation. Enfin, nous proposons des pistes de solutions pour optimiser le dispositif actuel. [less ▲]

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See detailDevelopment and Identification of a Closed-Loop Model of the Cardiovascular System Including the Atria
Pironet, Antoine ULg; Revie, James A.; Paeme, Sabine ULg et al

Conference (2012, August 31)

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See detailSymmetries in the three-Higgs-doublet model
Ivanov, Igor ULg

Conference (2012, August 31)

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See detailThe role of distinctiveness in person recognition from faces and voices
Barsics, Catherine ULg; Brédart, Serge ULg

Conference (2012, August 30)

Objectives: When we recognize a familiar person, we can retrieve different kinds of information about her/him: semantic information (e.g. the person’s occupation), episodic information, such as a memory ... [more ▼]

Objectives: When we recognize a familiar person, we can retrieve different kinds of information about her/him: semantic information (e.g. the person’s occupation), episodic information, such as a memory of a specific occasion on which this person has previously been encountered and lexical information (i.e. the name). Recent findings indicated that semantic and episodic information retrieval is more likely to be elicited following familiar face than voice recognition. The present study was designed in order to explore the potential role of stimulus distinctiveness as an underlying factor of the face advantage. Design: The design included two within-subject factors: the stimulus domain (faces or voices) and the stimulus distinctiveness (distinctive or typical). Methods: The proportions of episodic and semantic information recalled following the recognition of famous faces and voices was assessed, using an adapted version of the Remember/Know paradigm. Results: In line with earlier results, more semantic and episodic information was retrieved from faces than voices. Moreover, semantic information was better retrieved from distinctive than typical stimuli. Nonetheless, distinctiveness impacted less than domain on the recall of semantic information, since more semantic details were retrieved from typical faces than from distinctive voices. Conclusions: These results are discussed in the light of current models of person recognition. [less ▲]

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See detailAccompaniment - a professional care?
Pirard, Florence ULg

Conference (2012, August 30)

In the European contexts where the structure of service supply is divided and where the initial trainings of professionals of childcare services are inaccurate (low levels, a focus on medical approach ... [more ▼]

In the European contexts where the structure of service supply is divided and where the initial trainings of professionals of childcare services are inaccurate (low levels, a focus on medical approach without adopting a more global psycho-educational view, etc.), several ways of professional developments could be considered as « professional care». The case of the Brussels-Wallonia Federation shows the importance of educational orientations for all services (for children between 0-12 years) thanks to curricula understood as tools of professionalization (rather than of standardization) (OCED, 2001, 2006, 2012). The case also illustrates the necessity to have a comprehensive set of coordinated actions of professional accompaniment for several years (Pirard, 2011; Pirard, Barbier, 2012). This accompaniment could be considered as a «professional care» that acknowledges the process of individual and collective competencies growing when certain conditions are guaranteed (Urban, al., 2011). [less ▲]

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See detailEstimation of genetic parameters for longitudinal measurements of feed intake in Piétrain sire lines
Dufrasne, Marie ULg; Jaspart, Véronique; Wavreille, José et al

Conference (2012, August 30)

The aim of this study was to estimate the genetic parameters for longitudinal measurements of feed intake (FI) in a crossbred population of pigs to develop a genetic evaluation model for the estimation of ... [more ▼]

The aim of this study was to estimate the genetic parameters for longitudinal measurements of feed intake (FI) in a crossbred population of pigs to develop a genetic evaluation model for the estimation of breeding values for FI of Piétrain boars. Data were collected on crossbred pigs in test station in the context of the genetic evaluation system of Piétrain boars in the Walloon Region of Belgium. Trait analyzed was daily FI (DFI). Because there were no facilities to record individual DFI in the Walloon test station, individual DFI were assumed to be the total pen FI divided by the number of pigs per pen. The edited dataset consisted of 3,902 measurements of DFI recorded on 1,975 crossbred pigs from 75 purebred Piétrain sires and 150 Landrace dams from the hyperprolific Landrace K+ line. A random regression animal model with fixed effects of sex and pen, and random effects of additive genetic, permanent environment and residual was developed in this study. Random additive genetic and permanent environment effects were modeled with linear splines with knots located at 75, 100, 175 and 210 d. The mean DFI was 1.979 kg/d with a SD of 0.479 kg/d. Estimated heritability for DFI increased with age from 0.02 at 75 d to 0.30 at 210 d. Estimated genetic correlation between age decreased when age interval increased. These preliminary results are consistent with literature. However, additional research are ongoing to test alternative random regression models that should be better than using splines for longitudinal performance of DFI. Furthermore, genetic relationship between DFI and other production traits, like growth and carcass traits, must be analyzed. [less ▲]

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