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See detailEpithelial-to-mesenchymal transition (EMT)-regulated soluble factors mediate tumor angiogenesis and myeloid cell recruitment
Suarez-Carmona, M; Bourcy, M; Lesage, J et al

Conference (2015, October 13)

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See detailWiMUAS: New inventory method to perform wildlife counts with UAS and review the large datasets
Linchant, Julie ULg; Lhoest, Simon ULg; Semeki, Jean et al

Conference (2015, October 13)

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See detailPresentation of a simplified method for the crashworthiness of offshore wind turbine jackets
Pire, Timothée ULg; Le Sourne, Hervé; Buldgen, Loïc ULg et al

Conference (2015, October 13)

More and more offshore wind farms will be built in a near future and it is mandatory to perform for every new project a collision risk analysis. Actually, this is done by using finite elements software ... [more ▼]

More and more offshore wind farms will be built in a near future and it is mandatory to perform for every new project a collision risk analysis. Actually, this is done by using finite elements software, which is time consuming and not suitable for pre-design stage. The presentation show analytical developments performed in order to assess the crashworthiness of an offshore wind turbine jacket quickly. [less ▲]

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See detailTracks as a non-invasive tool for monitoring large carnivores
Authelet, Manon ULg; Vermeulen, Cédric ULg

Conference (2015, October 13)

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See detailIndex de résistance à la fatigue: que garder?
Paulus, Julien ULg; Bosquet, Laurent; Forthomme, Bénédicte ULg

Conference (2015, October 10)

Objective Isokinetic tests regularly contribute to the assessment of muscle performance. However, to evaluate an athlete who mainly uses the lactic anaerobic metabolism to perform or in specific ... [more ▼]

Objective Isokinetic tests regularly contribute to the assessment of muscle performance. However, to evaluate an athlete who mainly uses the lactic anaerobic metabolism to perform or in specific pathological contexts, fatigue-resistance protocol could be complementary to short maximal strength evaluation. Although the reproducibility of the protocol has been demonstrated by Bosquet et al. (2010), what about the reproductibility of the measured parameters and various "fatigue index" proposed by dynamometers and used in the clinic and in the literature? Material & method Seventeen subjects, moderately active, performed 30 reciprocal maximal concentric contractions on three occasions with one 7-10 days recovery between each session. The peak torque (PT) and the maximal work (MW) of each repetition computed and subsequently use to compile eleven measured parameters and build forty-four index. The reproducibility of each parameter and index was evaluated through their ICC (2,1), SEM and respective MD. Results The ICC values of the measured parameters for the knee extensors are almost always higher than 0.8 while those for flexor range between 0.7 and 0.8. The ICC values for built "fatigue index" are less than 0.7 and 0.5 respectively for the extensors and flexors. No significant difference was observed between the reproducibility of PT and that of MW (whether for the extensors or flexors or for the measured parameters and "fatigue index"). Discussion In view of the values obtained in our population, it appears that no "fatigue index"or calculated quotient (quotient of the last x repetitions by the first x or accumulated repetitions by the best,...) seems sufficiently reproducible for clinical or scientific use! Only the measured parameters such as the best repetition, total or partial sum have a (very) high or excellent reproducibility and can therefore be used in clinical or research domain. References Bosquet, L., Maquet, D., Forthomme, B., Nowak, N., Lehance, C., & Croisier, J. L. (2010). Effect of the lengthening of the protocol on the reliability of muscle fatigue indicators. Int J Sports Med, 31(2), 82-88. [less ▲]

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See detailHepatitis E virus, an animal or a human virus?
Thiry, Damien ULg

Conference (2015, October 10)

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See detailEvaluation isocinétique du genou: quelle est la compatibilité entre différents dynamomètres?
Paulus, Julien ULg; Crielaard, Jean-Michel ULg; Croisier, Jean-Louis ULg et al

Conference (2015, October 10)

Objective The aim of this study was to assess the compatibility between dynamometer Biodex System 3 Pro, Con-Trex MJ PM-2 and Cybex Humac CSMI of knee extensors and flexors. Material & method Twenty-one ... [more ▼]

Objective The aim of this study was to assess the compatibility between dynamometer Biodex System 3 Pro, Con-Trex MJ PM-2 and Cybex Humac CSMI of knee extensors and flexors. Material & method Twenty-one subjects, moderately active, performed three isokinetic evaluation sessions with six to ten days of rest between each. Each of it, performed on a dynamometer in accordance with a different randomized order, included a concentric evaluation (60°.s-1 & 240°.s-1), eccentric (30°.s-1) and fatigue-resistance protocol (30 concentric repetitions maximum 180°.s-1) for the knee extensors and flexors. The peak torque (PT) and the maximal work (MW) of each repetition were recorded, as well as concentric and mixed agonists/antagonists ratios, to measure the compatibility inter-dynamometer two by two through their respective ICC (3.1), SEM and MD. Results For the short maximal strength test, ICC values for the extensors are almost always higher than 0.85 in concentric mode although they don't exceed 0.61 in eccentric mode. The ICC values for the flexor in slow concentric and eccentric mode are above 0.7, 0.75 and 0.8 for pairs Biodex/Cybex, Biodex/Con-Trex and Cybex/Con-Trex. None of ICC value exceeds 0.75 in fast concentric mode for the flexors. The ratios have ICC values lower than 0.6 except concentric ratio at 60°.s-1 for the pair Cybex/Con-Trex (0.83) and mixed ratio for the pairs Biodex/Cybex (0.73) and Cybex/Con-Trex (0.77). The ICC values of the parameters measured during the extensors fatigue-resistance protocol are mostly above 0.8 regardless of the pair of dynamometers considered. The ICC values of these parameters for the flexors are almost all lower than 0.7. Discussion Although the reproducibility of extensors in concentric mode is high, it's important to inform users, whether in clinical or scientific domain, that different dynamometers provide regular incompatible results and we draw attention to the little reproducibility of the agonist/antagonist ratios. Our results justify the establishment of norms for each dynamometers brand in order to interpret, with relevance, the isokinetic test, either for short maximal strength evaluation or fatigue-resistance protocol. [less ▲]

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See detailStable isotope ratios suggest limited trophic importance of seagrasses for invertebrate consumers from Malagasy tropical polyspecific seagrass meadows
Michel, Loïc ULg; Wang, Haolin; Frederich, Bruno ULg et al

Conference (2015, October 09)

Polyspecific seagrass meadows are of critical ecological importance in tropical coastal zones. These ecosystems provide a wide range of socio-economical services to local populations. Meadows however ... [more ▼]

Polyspecific seagrass meadows are of critical ecological importance in tropical coastal zones. These ecosystems provide a wide range of socio-economical services to local populations. Meadows however undergo multiple threats linked to human activities (increased nutrient input, overfishing, invertebrate overharvesting, etc.). It is currently difficult to assess how seagrass meadows could respond to anthropogenic impacts due to poor knowledge of their functional ecology. Here, stable isotope ratios of carbon, nitrogen and sulfur were used to unravel trophic interactions ruling the food webs associated to seagrass beds of the Toliara Great Reef (SW Madagascar). The contributions of various potential food items (sediment-associated and suspended particulate organic matter, plankton, leaves, roots and epiphytes of 7 seagrasses and thalli of 7 dominant macroalgae) to the diet of 20 invertebrate taxa (one sea urchin, 2 sea stars, 2 sea cucumbers, 5 gastropods including one sea hare, one bivalve, 2 amphipods, one leptostracan, one cumacean 2 hermit crabs and 3 shrimps) were assessed using a Bayesian stable isotope mixing model. Model outputs revealed that important trophic diversity existed among the invertebrate assemblage. In some groups (e.g. hermit crabs and amphipods), resource use by morphologically and taxonomically close taxa was markedly different. Many of the dominant taxa heavily relied on macroalgae for their nutrition. On the other hand, few species apparently consumed seagrass tissues. Moreover, when they did, seagrass generally accounted for a minor portion of the diet only. Overall, our results suggest that seagrass grazing in meadows of the Toliara Great Reef could be lower than in other tropical areas. These discrepancies could be linked with seasonal variation in resource availability or with eutrophication. Higher nutrient load is indeed known to cause ecosystem phase shifts and it may induce diet shift to algivory in some invertebrate consumers. [less ▲]

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See detailTowards new bioherbicides derived from barley root allelochemicals
Bouhaouel, Imen ULg; Gfeller, Aurélie; Fauconnier, Marie-Laure ULg et al

Conference (2015, October 09)

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See detailProgramme d'étirement appliqué à l'épaule raide : conséquences fonctionnelles
Forthomme, Bénédicte ULg; Croisier, Jean-Louis ULg; COLLIGNON, Pierre ULg et al

Conference (2015, October 09)

Les athlètes de lancer présentent une mobilité passive gléno-humérale de l’épaule dominante spécifique avec une majoration de la rotation externe et une limitation de la rotation interne. La limitation ... [more ▼]

Les athlètes de lancer présentent une mobilité passive gléno-humérale de l’épaule dominante spécifique avec une majoration de la rotation externe et une limitation de la rotation interne. La limitation interne semble liée à une raideur capsulo-musculaire postérieure, favorisant les pathologies de l’épaule sportive. Matériel et méthodes Vingt hommes, sportifs d’armer / lancer (volley-ball, handball) et pratiquant au moins 6 heures d’entraînement depuis plus de 5 années ont participé à cette étude. Ils présentaient tous une raideur des structures postérieures évaluée en clinique. Lors de l’inclusion dans l’étude, 10 athlètes (22,5 ± 4 ans) étaient asymptomatiques, 10 (24,8 ± 4 ans) présentaient une épaule dominante symptomatique (≥ 3/10 sur l’EVA). Les athlètes ont étiré chaque jour leur épaule dominante (sleeper stretch et cross body arm) pendant 4 semaines (5 x 30’'). Avant et après le programme d’étirement des structures postérieures, ils ont subi un test isocinétique de force maximale des rotateurs internes et externes ainsi qu’une analyse tridimensionnelle définissant la cinématique scapulaire. Résultats Après 4 semaines d’étirement des structures postérieures, tous les athlètes ont montré un gain significatif de mobilité en rotation interne passive. Nous n’observons aucune modification de la cinétique scapulaire lors de l’analyse 3D après les étirements chez les athlètes asymptomatiques ; les athlètes symptomatiques présentent une diminution du tilt antérieur scapulaire au repos après les 4 semaines. L’évaluation isocinétique des rotateurs d’épaules après les étirements montrent uniquement une légère réduction (- 4% ; p < 0,05) de la force des rotateurs internes à 60°/s en concentrique chez les athlètes asymptomatiques. Les sportifs qui décrivaient des douleurs avant les étirements sont significativement améliorés après le programme de 4 semaines ; cette diminution de la douleur est corrélée au gain en rotation interne passive. Discussion L’étirement pendant 4 semaines des structures postérieures de l’épaule raide sportive permet une augmentation de la mobilité passive. Ce gain de mobilité est corrélé à la diminution de la douleur chez les athlètes symptomatiques. [less ▲]

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See detailSpatial variations in concentrations of mercury and persistent organic pollutants in coastal bottlenose dolphins, Tursiops truncatus, from the Lower Florida Keys and the coastal Everglades (South Florida)
Damseaux, France ULg; Kiszka, Jeremy; Heithaus, Michael et al

Conference (2015, October 09)

The bottlenose dolphin (Tursiops truncatus) is a major apex predator and the most common cetacean species found in nearshore waters of South Florida, including the Lower Florida Keys (LFK) and the ... [more ▼]

The bottlenose dolphin (Tursiops truncatus) is a major apex predator and the most common cetacean species found in nearshore waters of South Florida, including the Lower Florida Keys (LFK) and the Everglades National Park (ENP). The objective of this study was 1) to assess contamination levels of total mercury (T-Hg) in skin and persistent organic pollutants (PCBs, PBDEs, DDT, HCH, HCB, DLCs and PCDD/Fs) in blubber samples of bottlenose dolphins from the LFK (T-Hg : nmales = 10; POPs : nmales = 16, nfemales = 8) and the ENP (T-Hg : nmales = 13, nfemales = 9; POPs : nmales = 11, nfemales = 8). T-Hg and POPs were analysed by the mean of Direct Mercury analyser (for T-Hg), GC-ECD (POPs) and GC-MS (DLCs and PCDD/Fs). The PCBs were the main compounds found in bottlenose dolphins from the LFK and ENP. The most present congeners where the CB no. 28, 52, 101, 138, 153 and 180 (Σ 6 PCBs LFK males: 13420.5 ng.g-1 lipids, Σ 6 PCBs LFK females: 9683.4 ng.g-1 lipids, Σ 6 PCBs ENP males: 5637.9 ng.g-1 lipids, Σ 6 PCBs ENP females: 1426.9 ng.g-1 lipids), while the concentrations of DL PCBs remained low for both locations (LFK: 739 ng.g-1 lipids, ENP: 183 ng.g-1 lipids). PCBs concentrations were significantly higher in individuals from the LFK than those from the ENP. PCBs concentrations in LFK and ENP dolphins were significantly lower than those from other locations in the south-eastern US. Unlike organic pollutants, T-Hg concentrations were significantly higher in ENP male dolphins (LFK: 2936.0 ng.g-1 dw, ENP: 10048.3 ng.g-1 dw). These high concentrations were the highest recorded in the south-eastern US and are most likely due to the presence of mangrove ecosystems. This study highlights the complexity of contaminant dynamics (inorganic vs. organic), even at small spatial scales. [less ▲]

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See detailEffect of evolutionary miniaturization on the tempo and mode of diversification - An example from marine angelfishes
Frederich, Bruno ULg; Santini, Francesco; Konow, Nicolai et al

Conference (2015, October 09)

Evolutionary change in body size is a widespread phenomenon in animals. Numerous studies have highlighted evolutionary miniaturization, referring to the evolution of small body size, in various taxa. As ... [more ▼]

Evolutionary change in body size is a widespread phenomenon in animals. Numerous studies have highlighted evolutionary miniaturization, referring to the evolution of small body size, in various taxa. As other traits shift, decrease in size can be viewed as a morphological novelty that enables colonization of new “adaptive zones” and subsequent diversification (i.e. a “key innovation”). Thus, evolution to small body size is hypothesized to influence lineage, morphological and ecological diversification. Until now, few studies have tested this hypothesis and current supports are mixed. Here, we present a quantitative analysis of the radiation of Pomacanthidae (angelfishes), an iconic coral reef fish family where small taxa, the so called “pygmy angelfishes” of the genus Centropyge, appear to have evolved three-times. If an evolutionary decrease in size has acted as a key innovation during the evolutionary history of Pomacanthidae, we predict that diversification rates would be the highest in clades of pygmy angelfishes. We produced a time-calibrated phylogeny including 67 species, collected ecological data and quantified the body shape of 80 species using geometric morphometrics. Then, we tested the prediction by modelling macroevolutionary dynamics of diversification using the Bayesian Analysis of Macroevolutionary Mixture (BAMM) framework. BAMM results do not support a common macroevolutionary regime for every pigmy angelfish clades. Only the clade Centropyge Xiphypops shows higher rates of lineage and morphological diversification than the other clades of angelfishes. We show that miniaturization has few effects on the rate of diversification. The shifts in the tempo of diversification observed in C. Xiphypops might instead be related to a functional innovation of the feeding apparatus. Using the Pomacanthidae, we illustrate that miniaturization may not be a main factor in triggering increased of diversification rates at the family level. [less ▲]

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See detailEtats de conscience altérée: évaluation clinique et techniques d'imagerie
Martial, Charlotte ULg

Conference (2015, October 07)

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See detailVie, institutions, politique : le cas Bergson
Caeymaex, Florence ULg

Conference (2015, October 06)

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See detailCurrent trend in carbon tetrachloride from several NDACC FTIR stations
Hannigan, J.; Palm, M.; Conway, S. et al

Conference (2015, October 05)

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See detailDe l'application des mathématiques en biologie : acquis et perspectives
Brostaux, Yves ULg

Conference (2015, October 03)

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See detailLeucocytes and lipid particles filtration in suction blood during cardiopulmonary bypass: impact on kidney function evaluated with a monocentric prospective randomized study.
LAGNY, Marc-Gilbert ULg; KOCH, Jean-Noël ULg; BLAFFART, Francine ULg et al

Conference (2015, October 03)

OBJECTIVE: Cardiac surgery may be complicated by acute kidney injury (AKI). Cardiotomy suction during cardiopulmonary bypass (CPB) is deleterious. A few studies have demonstrated that shed mediastinal ... [more ▼]

OBJECTIVE: Cardiac surgery may be complicated by acute kidney injury (AKI). Cardiotomy suction during cardiopulmonary bypass (CPB) is deleterious. A few studies have demonstrated that shed mediastinal blood (SMB) suction during cardiopulmonary bypass (CPB) can increase inflammatory response and lipids emboli. These 2 factors contribute to the development of postoperative AKI. The RemoweLL (RemoweLeucoLipids, Eurosets™, Italy) filter is a recent designed cardiotomy with a multilayer filter for activated leucocytes filtration and a syphon for lipid particles sequestration. The SMB can be collected and filtered in this supplementary cardiotomy added to CPB circuit. The aim of this monocentric prospective study was to compare the specific RemoweLL cardiotomy filtration for suction blood during CPB and a conventional 40 µm filter (Admiral, Eurosets™, Italy). The primary goal was to evaluate the AKI within 48 hours after surgery using the Acute Kidney Injury Network classification (AKIN classification) but also measuring early specific biomarkers of AKI: serum Cystatine C and urinary neutrophil gelatinase-associated lipocalin (NGAL). METHODS: Sixty patients scheduled for elective cardiac surgery (aortic or mitral valvular combined or not with coronary bypass grafting) with a glomerular filtration rate (GFR) > 45mL/min. were randomly into 2 groups for SMB filtration: - Groupe 1 (n=30) with RemoweLL cardiotomy (Leucocytes and lipids filter); - Groupe 2 (n=30) with Admiral cardiotomy (conventional 40 µm filter). All components: venous reservoir, oxygenator and surface treatment were similar in both groups. [less ▲]

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See detailBaccio Bandinelli théoricien. Réflexions sur le "Libro del Disegno"
Marique, Charlotte ULg

Conference (2015, October 02)

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See detailConclusions
Valenti, Gianluca ULg; Miesse, Hélène ULg

Conference (2015, October 02)

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See detailNovel chitosan hydrogel for the treatment of osteoarthritis.
Henrotin, Yves ULg

Conference (2015, October 02)

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See detailDGTs, a complementary tool towards more efficient biomonitoring practices
Richir, Jonathan ULg; Lepoint, Gilles ULg; Donnay, Annick et al

Conference (2015, October 01)

Among the diversity of contaminants, trace elements (TEs) remain of concern because of their persistence, their ability to accumulate in biota and their toxicity. The direct measurement of their dissolved ... [more ▼]

Among the diversity of contaminants, trace elements (TEs) remain of concern because of their persistence, their ability to accumulate in biota and their toxicity. The direct measurement of their dissolved concentrations only gives punctual and fluctuating information, and often remains below detection limits of analytical methods. The more appropriate use of sentinel organisms, or bioindicators, to monitor TEs has thus often been preferred in environmental surveys. The introduction of the diffusive gradients in thin films (DGTs) technique has however participated to progressively change this binary view - bioindicator vs water - of the coastal monitoring of TEs, and DGTs rapidly became a relevant complementary tool to bioindicators, has illustrated below. In the framework of the STARECAPMED project, the ecology and the ecotoxicology of TEs were studied in the seagrass Posidonia oceanica (L.) Delile and the mussel Mytilus galloprovincialis Lamarck, 1819. DGTs (free- and pore-water probes) were deployed before sampling of organisms. TEs were also analyzed in suspended matter (dissolved and suspended-particulate TE speciation). Studies were performed in the Calvi Bay (Corsica, France), northwestern Mediterranean. TE concentrations in organisms and suspended matter or in DGT resins were measured by DRC-ICP-MS after HNO3/H202 mineralization or after a 24h elution in HNO3 1M, respectively. (1) TE bioaccumulation was first seasonally studied in P. oceanica over 3 years. Dissolved TE concentrations monitored with DGTs were low to very low. TE bioaccumulation dynamics in P. oceanica could thus be linked to the natural physiological cycle of the plant, in clean environmental conditions. (2) To complement that field survey, isolated seagrasses were in situ contaminated with TEs at environmental relevant concentrations. Through the use of DGTs, TE uptake kinetics were modelled for seagrasses exposed to know bioavailable concentrations of contaminants, as were loss kinetics during the following depuration phase. The TE sequestration ability of a healthy P. oceanica meadow facing sudden trace metal contamination events could also be quantified. (3) The deployment of pore-water DGT probes in bare-sand or seagrass colonized sediments further showed that, through its stabilizing function of the seabed, P. oceanica maintained higher TE levels in the pore-water. P. oceanica meadows thus offer a significant “depuration-filtering” ecological service along highly anthropized Mediterranean coasts. M. galloprovincialis are widely used in large spatial scale coastal monitoring surveys. (4) The deployment of caged mussels together with DGTs showed that the little contaminated water body of the Calvi Bay was relatively homogenous. It also allowed to calculate TE bioaccumulation towards mussels in reference conditions, and to compare it to native mussel populations. (5) Finally, during a 5 months mussel caging survey, mussels and suspended matter were collected weekly to monthly, such as were deployed DGTs. The physiological status of mussels, the speciation of TEs between their dissolved and suspended-particulate phases, and their relative influence on TE bioaccumulation dynamics in mussels were investigated. In conclusion, these case studies properly demonstrate how DGT probes can be used as a relevant and complementary tool to bioindicators. Their concomitant use should therefore be privileged in monitoring surveys. [less ▲]

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See detailTranscriptionally active HPV infection in the cervical squamo-columnar junction
Herfs, Michael ULg

Conference (2015, October 01)

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See detailLe droit de vote à distance: Emergence d'un objet de recherche et apport au champ de la sociologie électorale
Lafleur, Jean-Michel ULg

Conference (2015, October 01)

Dans cet article, nous présentons tout d’abord l’émergence du droit de vote à distance comme objet de recherche dans le champ la théorie politique et des études migratoires. Ces travaux caractérisés par ... [more ▼]

Dans cet article, nous présentons tout d’abord l’émergence du droit de vote à distance comme objet de recherche dans le champ la théorie politique et des études migratoires. Ces travaux caractérisés par leur dimension exploratoire, nous permettent toutefois de définir le droit de vote à distance et d’identifier les caractéristiques essentielles qui le différencie aujourd’hui des pratiques antérieures. Nous présentons ensuite les travaux sur la diffusion de la norme qui depuis moins d’une décennie ont constitué le principal angle d’entrée de la science politique sur le droit de vote à distance. Dans la troisième et dernière partie de l’article, nous défendons enfin l’intérêt d’une approche transnationale des questions électorales dans les études électorales. Cette approche, comme nous le défendons, permet d’éclairer non seulement le comportement des expatriés mais plus largement la transformation des pratiques électorales ici et là-bas. [less ▲]

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See detailComment décrire la musique expérimentale ? Le cas de Vital Weekly
Claisse, Frédéric ULg

Conference (2015, October 01)

Publiée de manière interrompue sous forme de courrier hebdomadaire depuis 1995, le magazine Vital Weekly est un observateur privilégié de vingt ans d’évolution dans le domaine des musiques expérimentales ... [more ▼]

Publiée de manière interrompue sous forme de courrier hebdomadaire depuis 1995, le magazine Vital Weekly est un observateur privilégié de vingt ans d’évolution dans le domaine des musiques expérimentales. La communication revient sur ce corpus de 1001 numéros, qui voit les chroniqueurs progressivement inventer une forme de critique musicale radicale, gratuite et libre d’accès, sans prétention stylistique ou journalistique, visant l’informativité avant tout, à destination d’une communauté de lecteurs dont beaucoup sont eux-mêmes producteurs ou musiciens. Le magazine illustre la situation hybride des musiques expérimentales, appellation commode et fourre-tout pour des pratiques musicales extrêmement diversifiées, qui doivent autant aux traditions « savantes » du XXe siècle (field recordings, musique concrète, musiques électro-acoustiques, poésie sonore, …) qu’à l’esprit Do-It-Yourself et à l’esthétique industrielle de la cassette culture ayant émergé au tournant des années 1970-1980. D’inspiration pragmatique, l’analyse sociologique présentée ici prend au sérieux l’épreuve perceptive que représente pour le chroniqueur la rencontre avec un matériau sonore qui défie le jugement esthétique. Exemples à l’appui, il s’agit d’expliciter les « prises » de la critique sous contrainte de descriptivité : quels sont les repères conventionnels sur lesquels s’appuyer pour situer l’objet musical dans un espace structuré (paratexte, épitexte, descripteurs de genre, références intertextuelles) ? quels sont les registres (étrangeté, malaise, onirisme, puissance, intimité, présence à soi, matérialité et textures) qui permettent de transmettre au lecteur l’expérience sensible d’un face-à-face avec un objet sonore bouleversant ? [less ▲]

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See detailChronos and Topos: The Inheritance of the Here-Now in Gail Jones’s Five Bells
Belleflamme, Valérie-Anne ULg

Conference (2015, October 01)

In an interview, Australian novelist, essayist, and academic Gail Jones claimed an interest in psycho-geography, i.e. “in the idea,” as she puts it, “that we must walk around our own place with an active ... [more ▼]

In an interview, Australian novelist, essayist, and academic Gail Jones claimed an interest in psycho-geography, i.e. “in the idea,” as she puts it, “that we must walk around our own place with an active intelligence and with a degree of radical attention to what is there.” Taking Sydney as an example, Jones insists on the importance of looking at the city’s “shapes, its motions,” of attending to its “sounds, corridors between spaces, the unexpected.” It is, she continues, “about apprehending things through shapes and signs.” Sydney, to her, is a place haunted by its colonial inheritance, and Australia, more generally, is a “colony of trauma”, a place where “there is always a tension between remembering and forgetting.” Thus time and space are merged, or to put it as Jones does, “within the material spaces of a city are these immaterial traces of something else.” Along the same lines, Jones distinguishes between a vertical and a horizontal history: on the one hand, she explains, “there is the history that seems to be unfolding and moving forward,” while on the other hand there is a “plunging down into the interiority of the place, into its lost history.” This merging together of time and space, of history and geography is an inherent attribute of cosmopolitanism as it finds an echo in Jones’s novel Five Bells, which takes place on a single day in cosmopolitan Sydney and draws together four characters with their different national backgrounds, haunting histories and memories, all converging on Circular Quay, an Aboriginal site also marked as the place where Captain Cook first set foot. Focusing on the characters’ migrant perceptions of this historical and iconic site, my paper will seek to investigate how Jones draws on the trope of temporal and spatial inheritance in Five Bells to offer “ethical understanding” as an alternative to today’s embattled conception of Australian national identity. [less ▲]

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See detailBuilding a bridge between Liege and Asturias : the case of zinc
Peters, Arnaud ULg

Conference (2015, October 01)

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See detailMars atmospheric escape constrained using MAVEN IUVS coronal observations
Chaffin; Deighan; Chauffray et al

Conference (2015, October)

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See detailPlankton ecosystem response to the decadal variation of winter intensity in the Mediterranean Sea : a long-term study (1979-2014)
Goffart, Anne ULg; Collignon, Amandine ULg; Hecq, Jean-Henri ULg et al

Conference (2015, October)

In the Mediterranean Sea, several studies with distinct data sets indicate that the pelagic ecosystem underwent periods of change in the late 1980s and in the early 2000s. Here we used a unique long-term ... [more ▼]

In the Mediterranean Sea, several studies with distinct data sets indicate that the pelagic ecosystem underwent periods of change in the late 1980s and in the early 2000s. Here we used a unique long-term time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) from 1979 and 2014 to explore the synchrony between changes in environmental conditions and phyto- and zooplankton dynamics. We identified an almost decadal, long-term variability in winter intensity, with three distinct periods: the 1980s (1979-1988), the 1990s (1989-1998) and the 2000s (1999-2014), which were characterized by moderate, mild and highly variable winters, respectively. We pointed out how the decadal changes in winter intensity affected (i) the duration and intensity of phyto- and zooplankton blooms, (ii) the mean yearly biomasses, and (iii) the nature of the assemblages. High phyto- and zooplankton biomasses were observed in years characterized by moderate and severe winters, and low phyto- and zooplankton abundances were recorded in years with mild winters. Moderate/severe and mild winters were favorable for diatoms and gelatinous zooplankton, respectively. Focusing on meroplanktonic species, we explored ecological consequences of decadal variations observed in the Bay of Calvi for resource management. We highlighted parallelisms with other European seas. [less ▲]

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See detailThe role of LMIs in supporting nonstandard professional transitions
Pichault, François ULg

Conference (2015, October)

The succession of economic and financial crises has led to the development of multiple categories of jobs ranging from unemployment and precarious jobs to full-time salaried positions (Schmid, 2015 ... [more ▼]

The succession of economic and financial crises has led to the development of multiple categories of jobs ranging from unemployment and precarious jobs to full-time salaried positions (Schmid, 2015). Between these two “extreme” situations, a “grey zone” of hybrid work categories is developing, with jobs supported by public authorities, temporary jobs, integration programs via internships and intensive training, incubators for new entrepreneurs, franchising, contract work, etc. The main common feature of such hybrid categories is a progressive transformation of the traditional employment relationships towards “multilaterality” (Countouris, 2007). If a context of nonstandard work arrangements (Cappelli & Keller, 2013) paves the way to nonstandard forms of professional transitions, it may also drive dissatisfaction, as the growing grey zone of hybrid statuses may be associated with cumulated precariousness, without counterparts (Kalleberg, 2009). Professional transitions through alternative work arrangements raise many questions in terms of job security, continuity of wage, skills development, integration into the social security system, etc. (Davidov, 2004; Havard et al., 2009; Keller & Seifert, 2013; Wears & Fisher, 2012). Who should take care of these issues? If individuals are no longer following a classical organisational and/or professional career, to what extent must their career path be automatically considered as their own responsibility and a result of their entrepreneurial capabilities? Between the “hierarchical” steering of organisational careers and the free “market” interplay specific to boundaryless careers (Arthur & Rousseau, 1996), there is a place for median formulas, seeking to both relieve individuals of the administrative difficulties linked to a discontinuous series of different statuses, while offering them new services that meet simultaneously their demands for flexibility and security. Our paper explores the extent to which such Labour Market Intermediaries (LMIs) can effectively secure nonstandard career paths. In order to characterize their roles, we created a multidimensional grid made up of 6 criteria: 1) partnership logic, 2) responsibility for matchmaking, 3) prevailing regulatory framework, 4) HR packages offered, 5) availability of information produced and 6) innovativeness. We illustrate this analytical framework via several case studies of LMIs operating in Belgium. Beyond the creation of an original multidimensional grid, our results outline two ideal-typical ways of securing nonstandard careers paths. Some LMIs reconstruct internal labour markets and operate as “quasi-employers”. Others suggest more disruptive solutions in which workers are supported while becoming fully responsible for their career as “self-employers”. Between these two extreme situations, many other possibilities may emerge according the variations of each criterion. Our multidimensional grid is an attempt to enrich existing typologies provided by the literature (Autor, 2008; Benner, 2003; Bonet et al., 2013). At the end of our analysis, a challenging hypothesis emerges from our empirical material. Once the support offered by LMIs goes away from the traditional employment patterns, a radical shift seems to occur in the purpose of career management: it is no longer a question of securing the employment relationship itself but rather a question of smoothing over welfare entitlements and incomes through professional transitions. It probably reflects more profound changes in the labour market, under the aegis of an active welfare State (Van Berkel et al., 2011)… [less ▲]

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See detailThe antibiotic resistance in the environment
Bardiau, Marjorie ULg

Conference (2015, October)

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See detailL’institution de la contre-culture
Saint-Amand, Denis ULg

Conference (2015, October)

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See detailApparatuses as loci of bio-political emergence: development of genetic testing in Belgium
Fallon, Catherine ULg

Conference (2015, October)

In his vision of “biopolitics” Lemke (2011) proposes to conceptualize life and politics as entities intertwined within a dynamic relationship. These technologies change the production of norms and the ... [more ▼]

In his vision of “biopolitics” Lemke (2011) proposes to conceptualize life and politics as entities intertwined within a dynamic relationship. These technologies change the production of norms and the apparatuses (Foucault 2008) organizing the distribution of the living in the domain of utility: therefore biopolitics must be analyzed as center pieces in the transformation of politics. The developments in genomics and epigenetics support the vision of the individual body as an “information network” rather than a physical substrate. The experts (with the active support of the patients) construct models for the calculation of life in the development of policy regulation and contribute actively to frame the policy relevant issues – either at individual or at population level, on the basis of power strategies mobilizing and disseminating specific forms of knowledge which are disciplined and selective. The contribution will present the recent evolution of the apparatuses producing the technical regulation and financial norms for the use of genetic testing in the federal Belgian public health system, considering the two complementary level of the “dispositif” : - At the political level, transformation of the « Conseil supérieur de la Génétique humaine » (1973-2013) into a « Collège de médecins pour le centre de génétique humaine » and the development of new control relations between the subsidizing and control bodies and the hospitals, - At the individual level, transformation of the cooperation between medical doctors, biomedical experts and psycho-sociologists in the relationship with the patients, as they can be observed at the level of the hospital; Who has the resources (intellectual, technological or financial) to control the technology and its use ? what are the social, institutional and technological constrains? who defines and select the legitimate options ? The analysis is not so much normative than critical, giving due attention to the social context and contingent rationalities in the evolution of this peculiar political action, with the aim of opening new areas of discussions transgressing disciplinary and institutional borders which are too often considered as self evident. [less ▲]

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See detailSoil production and hillslope transport in mid-latitudes during the last glacial-interglacial cycle: A combined data and modelling approach in northern Ardennes
Bovy, Benoît ULg; Braun, Jean; Demoulin, Alain ULg

Conference (2015, October)

The relative efficiency of various hillslope processes through Quaternary glacial-interglacial cycles in the mid-latitudes is not well constrained. Based on a unique set of topographic and soil thickness ... [more ▼]

The relative efficiency of various hillslope processes through Quaternary glacial-interglacial cycles in the mid-latitudes is not well constrained. Based on a unique set of topographic and soil thickness data in the Ardennes (Belgium), we combine the new CLICHE model of climate-dependent hillslope evolution with an inversion algorithm in order to get deeper insight into the ways and timing of hillslope dynamics under one such climatic cycle. We simulate the evolution of a synthetic hill reproducing the terrain attribute distributions of the hillslopes of a ~2500 km2 real area under a simple two-stage 120-kyr-long climatic scenario with linear transitions. The inversion method samples a misfit function in the model parameter space, based on estimates of the fit of topographic derivative distributions in classes of soil thickness and of the relative frequencies of the predicted soil thickness classes. Though the inversion results show convergence patterns for several parameters, no unique solution emerges. We obtain five clusters of good fits, whose centroids are taken as acceptable model solutions. Based on the predicted time series of average denudation rate and soil thickness, plus snapshots of the soil distribution at characteristic times, we compare these solutions with independent data not involved in the misfit function and identify the most realistic one. Providing first-order estimates of several parameters that compare well with published data, it shows that denudation rates increase dramatically at both warm-cold and cold-warm transitions when the mean annual temperature passes through the [0, -5°C] range. It also underlines the overwhelming importance of gelifluction in transporting soil and shaping hillslopes. [less ▲]

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See detailBelgian wildlife as potential zoonotic reservoir of hepatitis E virus
Thiry, Damien ULg

Conference (2015, October)

Hepatitis E is an acute human liver disease in healthy individuals but may become chronic. It is caused by the hepatitis E virus (HEV) and can have a zoonotic origin. In this study, 383 sera from wild ... [more ▼]

Hepatitis E is an acute human liver disease in healthy individuals but may become chronic. It is caused by the hepatitis E virus (HEV) and can have a zoonotic origin. In this study, 383 sera from wild boars were selected for serology; for virology, 69 sera and 61 livers from young wild boars were used. A total of 189 and 235 sera of respectively red and roe deer were collected for serological analysis. For virology, 84 and 68 sera and 29 and 27 livers from respectively red and roe deer were sampled. An apparent seroprevalence of 34% was found in wild boars, 1% in red deer and 3% in roe deer. In order to assess the ELISA screening prevalence, Western blot (WB) analyses and a ROC curve analysis were performed. Different scenarios with varying ELISA specificities relative to WB were analysed. In wild boar, seroprevalence remained high whatever the scenario; 4 out of 69 sera and 4 out of 61 livers were detected as positive for HEV RNA. All sequences obtained from sera belonged to genotype HEV-3. HEV RNA, belonging to genotype HEV-3, was detected in one red deer liver. Wild boar can be considered as a host reservoir of the virus in Belgium. However, the low prevalence in deer makes these species an unlikely reservoir. This evidence needs further investigation in order to determine in which situation deer can serve as reservoir and raise the question of the dynamics of HEV infection between wild fauna, domestic pigs and humans. [less ▲]

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See detailSociology of literature and sociocriticism
Saint-Amand, Denis ULg

Conference (2015, October)

Detailed reference viewed: 17 (1 ULg)
See detailGestationnal trophoblastic diseases
GOFFIN, Frédéric ULg; Seckl, M

Conference (2015, October)

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See detailFonds 'vautours', contentieux des dettes souveraines et droit de propriété
Wautelet, Patrick ULg

Conference (2015, October)

Cette présentation a pour objectif de contextualiser la loi du 12 juillet 2015 visant à réprimer l'action des fonds dits 'vautours' en offrant une première analyse critique de la loi, principalement au ... [more ▼]

Cette présentation a pour objectif de contextualiser la loi du 12 juillet 2015 visant à réprimer l'action des fonds dits 'vautours' en offrant une première analyse critique de la loi, principalement au regard de la protection internationale du droit de propriété [less ▲]

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See detailLipid analysis on a putative early land plant and its matrix: Preliminary results
Versteegh, Gerath J.M.; Cascales-Miñana, Borja ULg; Gerrienne, Philippe ULg et al

Conference (2015, October)

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Peer Reviewed
See detailTriclosan retardes development of Sheepshead minnow (Cyprinodon variegatus)
Dussenne, Mélanie ULg; Frederich, Bruno ULg; Das, Krishna ULg et al

Conference (2015, October)

The aquatic environment represents the final sink for many chemicals, including bactericidal agents. Among them Triclosan (TCS), with his chemical structure similar to thyroid hormones (THs), may have ... [more ▼]

The aquatic environment represents the final sink for many chemicals, including bactericidal agents. Among them Triclosan (TCS), with his chemical structure similar to thyroid hormones (THs), may have adverse effects on the thyroid system. The study we carried out aims to evaluate the effects of TCS exposure on development of Cyprinodon variegatus, a fish model used in ecotoxicological studies. We investigated the potential effects of TCS on C. variegatus during two key periods; embryonic development and metamorphosis. We exposed eggs and larvae to environmental relevant concentrations. We showed that TCS had no effect on reproduction parameters, such as egg fertility or survival rate of larvae. However, we highlighted the fact that hatching of exposed larvae was delayed of around 6 to 13 hours compared to control embryos. During the larval phase, measurements of THs levels were performed. We showed that TCS affected the typical ontogenic variations of the whole body thyroid hormones concentrations during metamorphosis. As THs are known to control somatic growth and development, we tested the effects of TCS exposure on morphological development. We observed no deformity or malformation, but we revealed a developmental retardation in larvae exposed to TCS, of around 18 to 32 hours. Such a developmental delay had never been highlighted in previous studies on TCS exposed fish. We hypothesize that the disruption of THs homeostasis affects the timing of the start of metamorphosis. As a consequence, exposed larvae showed an extended larval phase compared to the control group. The harmful effects of TCS on physiology and development are a major concern, as marine organisms are constantly exposed to it. Furthermore, strong connections exist between thyroid and reproductive system, which might have deleterious effects on population dynamics. [less ▲]

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See detailDéchéance de nationalité et terrorisme : quelle marge de manoeuvre pour l'Etat?
Wautelet, Patrick ULg

Conference (2015, October)

Cette présentation a pour objet de situer de manière critique les récentes interventions du législateur belge en matière de déchéance de la nationalité belge, en montrant quelles sont les limites ... [more ▼]

Cette présentation a pour objet de situer de manière critique les récentes interventions du législateur belge en matière de déchéance de la nationalité belge, en montrant quelles sont les limites internationales à l'action du législateur national. Le cadre législatif en vigueur en Belgiqe est analysé en particulier à la lumière de l'interdiction de discrimination [less ▲]

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See detailDévelopper l'autorégulation et les compétences en résolution de problèmes : une étude exploratoire en fin d'enseignement primaire
Fagnant, Annick ULg; Jaegers, Doriane ULg

Conference (2015, October)

L’article s’appuie sur une étude exploratoire en fin d'enseignement primaire (grade 6, élèves de 11-12 ans). L’approche d’enseignement/apprentissage mise en place visait conjointement à développer des ... [more ▼]

L’article s’appuie sur une étude exploratoire en fin d'enseignement primaire (grade 6, élèves de 11-12 ans). L’approche d’enseignement/apprentissage mise en place visait conjointement à développer des capacités d’autorégulation et l’apprentissage d’une démarche de résolution de problèmes en favorisant les régulations interactives et, particulièrement, le recours à une grille de co-évaluation. Le dispositif quasi-expérimental de l’étude permet d’apprécier les progrès plus importants des élèves de la classe expérimentale (comparativement à une classe contrôle) en termes de performances mais aussi d’une certaine anticipation et planification de la démarche de résolution. Ils démontrent aussi de meilleures capacités d’autoévaluation. Les entretiens réalisés avec quelques élèves permettent de mettre en évidence la plus-value des différentes formes de régulations interactives mises en place. Enfin, plusieurs éléments permettent également d’émettre l’hypothèse d’un impact positif de l’approche sur les variables affectives et motivationnelles. [less ▲]

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See detailLaparoscopic management of bladder endometriosis
BRICHANT, Géraldine ULg; NICOLAS, Hubert; NISOLLE, Michelle ULg

Conference (2015, October)

Detailed reference viewed: 21 (3 ULg)
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See detailValorisation de la biomasse pour des applications vers des marchés de niche
Richel, Aurore ULg

Conference (2015, October)

Dans le contexte économique actuel de notre société, il est reconnu que des alternatives et des compléments à la pétrochimie devront être développés dans un futur proche. L’une des solutions possibles ... [more ▼]

Dans le contexte économique actuel de notre société, il est reconnu que des alternatives et des compléments à la pétrochimie devront être développés dans un futur proche. L’une des solutions possibles réside dans le développement de procédés permettant de substituer les actuels produits pétro-sourcés par de nouveaux matériaux bio-basés issus de la biomasse. Sur base de ce constat, Gembloux Agro-Bio Tech et son laboratoire de Chimie Biologique Industrielle se positionnent sur cette thématique en abordant les aspects technico-économiques de transformation du végétal en une gamme de produits à haute valeur ajoutée à destination de divers secteurs applicatifs tels que les matériaux, le cosmétique, le pharmaceutique, etc. L'importance de l'agronomie et des techniques agricoles, combinée à une gestion appropriée des déchets en circuits courts, sont deux piliers discutés dans ce exposé et illustrés au travers de divers exemples stratégiques. [less ▲]

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See detailImplication of adamalysin proteases in mesothelioma
Sepult, Christelle ULg; Rocks, Natacha ULg; Bekaert, Sandrine et al

Conference (2015, September 30)

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See detailBetter tests better care : Syndrome-based diagnostics for respiratory tract infections
MELIN, Pierrette ULg

Conference (2015, September 29)

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See detailSimulations of the auroral signatures of Jupiter’s magnetospheric injections
Dumont, Maïté ULg; Grodent, Denis ULg; Radioti, Aikaterini ULg et al

Conference (2015, September 29)

We report the evolution of ultraviolet auroral features located equatorward of the main emission appearing in the Hubble Space Telescope (HST) images of the northern and the southern Jovian hemisphere. We ... [more ▼]

We report the evolution of ultraviolet auroral features located equatorward of the main emission appearing in the Hubble Space Telescope (HST) images of the northern and the southern Jovian hemisphere. We investigate the possibility that those ultraviolet auroral structures are associated with energetic particle injections. For this study, we compare the characteristics of the simulated auroral signature of plasma injections with the observed parameters of equatorward isolated auroral structures. [less ▲]

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See detailPasser à Alma d’Ex Libris : projet de réinformatisation ? projet de bibliothèque ? L'expérience de l'Université de Liège 6 mois avant et 6 mois après
Renaville, François ULg; Thirion, Paul ULg

Conference (2015, September 29)

En janvier 2014, les Bibliothèques de l'Université de Liège ont décidé de passer au système de gestion de bibliothèque Alma. Le projet a débuté en août 2014 ; six mois après, la migration vers Alma et le ... [more ▼]

En janvier 2014, les Bibliothèques de l'Université de Liège ont décidé de passer au système de gestion de bibliothèque Alma. Le projet a débuté en août 2014 ; six mois après, la migration vers Alma et le lancement d'une nouvelle interface de découverte Primo étaient réalisés. Cette présentation balaye les moments clés de ce projet, en mettant l'accent sur la composante organisationnelle et la gestion du changement, ainsi que sur les premiers mois d’expérience avec le nouvel outil. [less ▲]

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See detailBien soigner l'arthrose: un enjeu capital pour notre société!
Henrotin, Yves ULg

Conference (2015, September 29)

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See detailDynamics of the active region in Jupiter’s aurorae
Bonfond, Bertrand ULg; Grodent, Denis ULg; Badman, Sarah et al

Conference (2015, September 29)

The Far-UV aurorae at Jupiter variety on a wide range of timescales. This study focuses on the dynamics of the active region on timescales of a few minutes. Up to now, only the time-tag mode of the Space ... [more ▼]

The Far-UV aurorae at Jupiter variety on a wide range of timescales. This study focuses on the dynamics of the active region on timescales of a few minutes. Up to now, only the time-tag mode of the Space Telescope Imaging Spectrograph provides access to such fast variations with a high spatial resolution. This active region, located on the dusk flank of the area inside the main auroral oval, is the locus of particularly bright (up to several mega Reyleighs) and sudden (a few tens of seconds) enhancements called flares. A previous study also showed that these flare could reoccur quasi-periodically every 2-3 minutes and propagate from dusk to dawn. Here we use data obtained in 2013 and 2014 to show that this quasi-periodic behavior is only present on half of the cases and that the affected region could either cover the whole active region or a much smaller area (∼5000km^2). We also found areas that were still during part of the observation sequence and then began to blink (see Figure 1). We also show that there no systematically preferred propagation direction. Finally, sequences acquired successively in the two hemispheres show that the quasi-periodic flares can be in phase [less ▲]

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See detailExperimental and in silico approaches to study the interaction of Remorin with plant plasma membrane : specific interaction of the C-term domain with lipids
Deleu, Magali ULg; Nasir, Mehmet Nail ULg; Gronnier, Julien et al

Conference (2015, September 29)

The function of Remorins, a diverse family of plant-specific proteins (1) is far to be fully elucidated. One of them, StREM1.3 (for Solanum tuberosum Remorin from group 1, homolog 3) has been reported to ... [more ▼]

The function of Remorins, a diverse family of plant-specific proteins (1) is far to be fully elucidated. One of them, StREM1.3 (for Solanum tuberosum Remorin from group 1, homolog 3) has been reported to regulate cell-to-cell propagation of the potato virus X (2). It was also shown to be localized to the inner leaflet of plasma membranes (PMs) and along plasmodesmata, bridges connecting neighbor cells essential for cell-to-cell communication in plants (3). The mechanisms driving StREM1.3 association with PM is still an open question. It was shown recently that a domain of 28 residues at the C-terminus of the potato (RemCA) is required and sufficient for anchoring to the PM (4). Here we combined experimental and in silico biophysics to unravel the molecular bases of RemCA membrane binding. Biomimetic membrane models of plant PM such as monolayers and liposomes were used with various biophysical techniques (Langmuir monolayer technique, Fourier-transformed infrared spectroscopy, circular dichroïsm) and modeling tools (home-made methods and molecular dynamics) (5) to answer to three questions: (i) What is the conformation adopted by RemCA within a membrane?, (ii) Is there any membrane lipid specificity in the RemCA-membrane binding? (iii) What is the role of the two different RemCA domains in the interaction? Results show that RemCA displays a preference for plant phosphoinositide and sitosterol-enriched inner leaflet plasma membrane rafts. Within the membrane, the C-terminal and the N-terminal domains adopt a random coil and a -helical conformation respectively. The C-terminal domain acts as a driver to bind RemCA to the membrane while the N-terminal domain stabilizes the peptide at the membrane. Lysine residues have a crucial importance in this interaction. References (1) Raffaele et al., Plant Physiol., 2007, 145: 593–600 (2) Raffaela et al., Plant Cell, 2009, 21: 1541–1555. (3) Maule, Curr. Opin. Plant Biol., 2008, 11: 680–686. (4) Perraki et al., Plant Physiology, 2012, 160 : 624-637. (5) Deleu et al., Biochim. Biophys. Acta – Biomembranes, 2014, 1838 : 3171-3190. [less ▲]

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See detailHigh-throughput sequencing of toxins with pharmacological interest: proof of concept and first applications
Echterbille, Julien ULg; Degueldre, Michel ULg; Boulanger, Madeleine ULg et al

Conference (2015, September 28)

Animal venoms are complex chemical cocktails, comprising wide ranges of biologically active reticulated peptides that target with high selectivity and efficacy varieties of membrane receptors. Assuming ... [more ▼]

Animal venoms are complex chemical cocktails, comprising wide ranges of biologically active reticulated peptides that target with high selectivity and efficacy varieties of membrane receptors. Assuming the fact that each of the 170,000 venomous species reported can produce more than 250 bioactive toxins, at least 40,000,000 bioactive peptides and proteins may be discovered. Among the four described species of mambas, Eastern Jameson’s mamba (Dendroaspis jamesonii kaimosae) venom is the less characterized since only 9 peptides are referenced in database. This work aims at developing a new strategy devoted to the deep analysis of animal venoms. Our approach consists in a first separation of the venom using cation exchange chromatography. Each primary fraction is then purified a second time by classical RP-HPLC. A total of 328 fractions, containing amongst 1 and 4 toxins, are finally collected. MALDI-MS analysis of each fraction is done in order (1) to obtain information about masses and (2) to obtain sequences of toxins thanks to MALDI-In Source Decay (ISD) dissociation coupled with on MALDI target plate reduction of the peptides. ISD has already been demonstrated efficient for toxin sequencing1, and especially when using 1,5-DAN as reducing matrix2. ISD yields to sequences that cover more than 50% of peptide sequences by series of singly charged c-type ions. Thanks to this methodology, we were able to obtain 85% of satisfactory results i.e. spectra giving quite long tags of amino acids (up to 20 residues). As a way to validate our method, a tag coming from ISD spectrum interpretation has found a match in database for an Eastern Jameson’s mamba toxin. The global sequence has then been obtained by extrapolation on the ISD spectrum. Since ISD spectra are simpler than classical MS/MS spectra, automation of spectra interpretation, difficult with other fragmentation techniques (CID, ETD…), is implementable. In the near future, sequences obtained with this approach will be used to direct tests of biological activity through sequence homologies with already known ligands for different kinds of membrane receptors. [less ▲]

Detailed reference viewed: 24 (7 ULg)
See detailPsychological benefits of a multidisciplinary rehabilitation program after breast cancer
Leclerc, Anne-France ULg; FOIDART-DESSALLE, Marguerite ULg; Bury, Thierry ULg et al

Conference (2015, September 27)

Background : Breast cancer is the most frequent cancer in women, affecting 8 women out of 100. With early detection and improved treatments, the number of deaths linked to this disease has declined ... [more ▼]

Background : Breast cancer is the most frequent cancer in women, affecting 8 women out of 100. With early detection and improved treatments, the number of deaths linked to this disease has declined. However, the disease and its treatments are at the origin of many undesirable side effects such as fatigue, anxiety, weight gain and sleep disorders. The objective of this study is to determine the psychological benefits of a multidisciplinary rehabilitation program among women treated for breast cancer (on average six months after the end of the adjuvant radiotherapy or chimiotherapy). Material and methods : 122 patients were included into a control group (n = 61) and a treated group (n = 61). All participants were submitted to evaluations before the beginning of the trial and after three months. These evaluations included different questionnaires exploring the quality of life, anxiety, depression and various functions and other symptoms related to cancer (EORTC QLQ-C30, EQ-5D, STAI, HADS) and functional assessments. The control group has received no intervention unlike the treated group that received a three-month rehabilitation including supervised physical training (90 min) with three times a week and various psycho-educational sessions (120 min) once a week. Results : After three months, the health status (quality of life) (p < 0,0001), the functional role (p = 0,031), emotional state (p < 0,0001) and physical (p = 0,0045), cognitive (p = 0,0027) and social functions (p = 0,0018) improve significantly in the treated group. This observation also applies to symptoms of fatigue (p < 0,0001), insomnia (p < 0,0001), pain (p = 0,002), dyspnea (p = 0,009), loss of appetite (p = 0,04), anxiety (p < 0,0001) and depression (p < 0,0001) as well as physical parameters obtained through functional assessments. In the control group, these improvements do not appear. Conclusions : This study shows the feasibility and psychological benefits of such a multidisciplinary oncological rehabilitation program in women after their treatments for breast cancer. Additional studies are needed to know the optimal time of beginning (during treatments or after them) and the optimal management time for this support. [less ▲]

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See detailHypoxic ischemic encephalopathy : new insights in neuroprotection
VIELLEVOYE, Renaud ULg

Conference (2015, September 26)

Hypoxic-ischemic encephalopathy (HIE) is a major contributor to neonatal morbidity and mortality and is a common cause of disability with devastating impact on individuals and families. During the acute ... [more ▼]

Hypoxic-ischemic encephalopathy (HIE) is a major contributor to neonatal morbidity and mortality and is a common cause of disability with devastating impact on individuals and families. During the acute phase, HIE is initially characterized by an excitotoxic cascade with hypoxic membrane depolarization, cytotoxic edema, glutamate release and intracellular accumulation of calcium leading to necrotic cell death and production of proinflammatory cytokines through the NF-κB pathway. In a second phase, reperfusion leads to production of free radicals, activation of proteases and phospholipases, exacerbing the damage to cell membrane and DNA and mitochondrial dysfunction causing caspase mediated apoptotic cell death. In a third phase, growth factors and inflammatory cytokines produced during the early phase of HIE attempt to repair damage induced by hypoxia–ischemia. Although the utility of therapeutic hypothermia induced in the 6 hours following HIE in the reduction of death or major neurodevelopmental disability is now well established in the neonate with moderate or severe encephalopathy, almost half of these children still die or have abnormal outcomes [1]. Protocols attempting to optimize cooling with deeper hypothermia (33.5°C vs 32.0°C) and/or longer duration (72h vs 120h), as well protocols studying neuroprotective effect of late hypothermia (6-24h) or hypothermia for 33-35 week GA preterm babies are currently performed. Furthermore, experimental data suggest that hypothermia extends the duration of the therapeutic window [2] and that certain drugs given during this time may improve neuroprotection either additively or synergistically. Xenon is a noble gas with anaesthetic and neuroprotective properties. It inhibits NMDA receptor, promotes cell survival and induces the production of erythropoietin and vascular endothelial growth factor through the hypoxia inducible factor 1 alpha (HIF-1α) pathway. Data from experimental piglet models of hypoxia-ischemia (HI) demonstrate a synergy when Xenon is administered in combination with mild therapeutic hypothermia [3]. In the human newborn, a phase-1 trial recently established that breathing 50% Xenon for up to 18 hours with 72 hours of cooling was feasible, with no adverse effects seen with 18 months’ follow-up [4]. A monocentric phase-3 trial is currently under process in England. Melatonin is a remarkable natural antioxidant but also exhibits antiapoptotic and anti-inflammatory properties in vitro. In animal models, melatonin administration prior or after the onset of HI significantly reduced infarct volume demonstrating both prophylactic and therapeutic effect [5-6]. When combined with hypothermia, melatonin enhances neuroprotection by reduction of the H–I-induced increase in clinically relevant biomarkers in the deep grey matter of newborn piglets [7]. Clinical studies confirmed its safety profile and its ability to reduce biomarkers level of HI in the human newborn [8]. Recently, a randomized controlled trial showed that the combination of melatonin and hypothermia administered to infants with moderate-to-severe H–I brain injury was efficacious in reducing oxidative stress, neonatal seizures and MRI brain lesions as well as in improving neurological outcomes at 6 months of age [9]. Erythropoietin (EPO) and its receptor are expressed in the developing central nervous system and are required for normal brain development. EPO is up-regulated in umbilical cord blood from babies who have suffered HI, which may be an endogenous repair mechanism. In vitro and in vivo neuroprotection induced by EPO is achieved by several mechanisms such as direct neurotrophic effect, direct antioxidant effects, decreased inflammation or regulation between pro-apoptotic and anti-apoptotic factors. Safety profile of EPO administration during hypothermia for newborns with HIE has been established in Phase I trials [10]. In a randomized prospective pase-2 trial, repeated low-dose rEPO reduced the risk of disability for infants with moderate but not severe HIE at 18 months, without apparent side effects [11]. A double-blind randomized controlled phase-3 trial is currently performed in France. Allopurinol is a xantine-oxidase inhibitor. In high concentrations it also scavenges hydroxyl radicals and prevents free radical formation. Allopurinol provides neuroprotection in rat and piglets models of HIE. In the human, a systematic review and meta-analysis of three studies on 114 newborns did not reveal statistically difference in the risk of death or a composite of death or severe neurodevelopmental disability between groups [12]. It was hypothesized that postnatal allopurinol treatment started too late to reduce reperfusion-induced free radical surge. However, in a recent study, allopurinol given to mothers during labor with fetal hypoxia did not significantly lower neuronal damage markers in cord blood even if post hoc analysis revealed a potential beneficial treatment effect in girls [13]. Magnesium sulfate (MgSO4) is a naturally occurring NMDA receptor antagonist. MgSO4 given to mothers at risk for preterm birth is associated with a reduced risk of cerebral palsy and gross motor dysfunction in their children. Its role as an adjuvant to therapeutic hypothermia in the asphyxiated term infant remains unclear. A recent review of preclinical studies using MgSO4 in HIE highlights the inconsistent impact between studies related to a lack of temperature control during and after HI, along with variability in the dose, timing of treatment [14]. A metaanalysis of five randomized controlled trials that compared magnesium to control in newborns with HIE showed a significant improvement in short term outcomes but no difference in the composite outcome of death or moderate to severe disability at 18 months [15]. Other NMDA and AMPA antagonist such as topiramate and memantine also exhibited neuroprotective properties in animal models but safety and efficacy in the human newborn with HIE still needs to be clarified [16]. N-acetyl cysteine (NAC) acts as a glutathione precursor with antioxidant, antiapoptotic, and anti-inflammatory properties. In a piglet model of HIE, NAC reduced cerebral oxidative stress, reduced cerebral lactate accumulation and improved cerebral perfusion. When combined with hypothermia in the asphyxiated rodent, NAC decreased infarct volume, improved myelin expression and functional outcomes on a synergistic pattern. NF-κB inhibitors and NO synthase inhibitors are other therapeutic options currently under investigation in in vitro and in vivo preclinical studies. Moreover, recent research performed at the University of Liege also suggests that Estetrol (E4), an estrogen synthetized exclusively by the human foetus, has neuroprotective properties in a rat model of HIE. Translation to clinical use in humans still needs to be studied [17]. Several therapies have also been suggested in order to improve mechanisms of repair and regeneration observed after the HI insult. Growth factors such as BDNF, IGF-1, EGF or bFGF can improve cell viability, stimulate the growth of new neurons or promotes oligodendroglial differentiation and myelination. Recent advances in regenerative medicine suggest that stem cell transplantation may improve repair of the damaged brain after HIE through the replacement of dead cells as well as through the release of trophic factors [18]. Animal preclinical data are promising. However many questions need to be answered with well-designed controlled trials before clinical application in daily practice. References [1] Edwards AD et al. (2010) Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data. BMJ. 340:c363. [2] O'Brien F et al. (2006) Delayed whole-body cooling to 33 or 35 degrees c and the development of impaired energy generation consequential to transient cerebral hypoxia-ischemia in the newborn piglet. Pediatrics 117:1549–59. [3] Chakkarapani, E. et al. (2010) Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs. Ann. Neurol. 68, 330–341 [4] Dingley, J. et al. (2014) Xenon ventilation during therapeutic hypothermia in neonatal encephalopathy: a feasibility study. Pediatrics 133, 809–818 [5] Carloni, S. et al. (2008) Melatonin protects from the long-term consequences of a neonatal hypoxic–ischemic brain injury in rats. J. Pineal. Res. 44, 157–164 [6] Hutton, L.C. et al. (2009) Neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (Acomyscahirinus). Dev. Neurosci. 31, 437–451 [7] Robertson, N.J. et al. (2013) Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model. Brain 136, 90–105 [8] Fulia, G. et al. (2001) Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin. Journal of Pineal Research; 31(4):343–349. [9] Aly, H. et al. (2015) Melatonin use for neuroprotection in perinatal asphyxia: a randomized controlled pilot study. J. Perinatol. 35, 186–191 [10] Wu, Y.W. et al. (2012) Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics. Pediatrics 130, 683–691 [11] Zhu, C. et al. (2009) Erythropoietin improved neurologic outcomes in newborns with hypoxic–ischemic encephalopathy. Pediatrics 124, 218–226 [12] Chaudhari, T. and McGuire, W. (2012) Allopurinol for preventing mortality and morbidity in newborn infants with hypoxic–ischaemic encephalopathy. Cochrane Database Syst. Rev. 7, Cd006817 [13] Kaandorp, J.J. et al. (2015) Maternal allopurinol administration during suspected fetal hypoxia: a novel neuroprotective intervention? A multicentre randomised placebo controlled trial. Arch. Dis. Child Fetal Neonatal Ed. 100, F216–F223 [14] Galinsky, R. et al. (2014) Magnesium is not consistently neuroprotective for perinatal hypoxia-ischemia in term-equivalent models in preclinical studies: a systematic review. Dev. Neurosci. 36, 73–82 [15] Tagin, M. et al. (2013) Magnesium for newborns with hypoxic–ischemic encephalopathy: a systematic review and meta-analysis. J. Perinatol. 33, 663–669 [16] Wu, Q et al. (2015) Neuroprotective agents for neonatal hypoxic–ischemic brain injury. Drug Discovery Today. [17] Tskitishvili, E et al. (2014). Estetrol attenuates neonatal hypoxic–ischemic brain injury. Experimental Neurology, 261, 298-307. [18] Kelen, D and Robertson, NJ. (2010) Experimental treatments for hypoxic ischaemic encephalopathy. Early Human Development 86; 369–377. [less ▲]

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See detailPhysicochimie de la pollution atmosphérique
Mahieu, Emmanuel ULg

Conference (2015, September 25)

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See detailEn tous quartiers ou j’ay esté. Le récit de pèlerinage de Georges Lengherand, mayeur de Mons (1486–1487)
Bruwier, Marie-Cécile; Docquier, Gilles; Marchandisse, Alain ULg

Conference (2015, September 25)

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See detailHabitants des petites villes et des villages face à la nature dans les paysages ordinaires
Vanderheyden, Vincent ULg

Conference (2015, September 25)

La recherche sur les perceptions paysagères dénigre souvent les paysages ordinaires, ces paysages modifiés par l’homme qui n’appellent pas à la protection. Pourtant, dans les régions de forte densité de ... [more ▼]

La recherche sur les perceptions paysagères dénigre souvent les paysages ordinaires, ces paysages modifiés par l’homme qui n’appellent pas à la protection. Pourtant, dans les régions de forte densité de population comme la Belgique, les paysages naturels sont rares ou inexistants, sans pour autant que la nature ait disparu des paysages ordinaires. Il est donc intéressant de se poser la question de la nature dans de tels paysages : à partir de quand un paysage est-il perçu comme naturel par ceux qui l’observent ou y vivent ? Les critères dépendent-ils du mode d’habiter (petite ville, village périurbain ou village rural) ou d’autres facteurs liés à la trajectoire biographique des gens ? Trois terrains d’études ont été retenus pour la recherche : la Wallonie picarde, l’Entre-Sambre et Meuse et l’Ardenne. Ces terrains offrent des paysages ruraux assez typés et suffisamment différenciés et éloignés des grandes agglomérations urbaines, hormis Tournai, ville d’envergure régionale. La Wallonie picarde présente des paysages de vastes plateaux agricoles limoneux au relief plan et peu élevé, occasionnellement surplombé de petites collines. L’Entre-Sambre-et-Meuse offre des paysages mixtes, alternant cultures, prairies et boisement dans un relief plus accidenté d’altitude moyenne. Enfin, l’Ardenne, troisième terrain, montre des paysages de hauts plateaux disséqués, dominés par les massifs forestiers et les pâturages. Ces terrains offrent un bel aperçu du continuum urbain-rural belge : de la petite ville en milieu rural au semis d’habitat très lâche du village ardennais, loin de l’habituelle dichotomie ville - campagne. Dans ces terrains, une approche empirique a été privilégiée. Nous y avons interviewé trois groupes de neuf étudiants (18-25 ans) d’un niveau d’éducation moyen (Bac +1 à Bac +3), non spécialistes en analyse du paysage, habitant dans de petites villes ou villages et un de leurs parents. Durant l’enquête, les personnes devaient classer des photos de paysages ruraux belges plus ou moins impactés par la présence de l’homme (habitat, cultures, éoliennes, pylônes, zones périurbaines) puis devaient motiver leur classement. Les entretiens ont été enregistrés, retranscrits et codés à l’aide d’un logiciel d’analyse qualitative. L’analyse de contenu montre des résultats contrastés. Un certain consensus indépendant du mode d’habiter semble se dégager concernant la présence d’éléments anthropiques récents, tels quel les éoliennes, les zones industrielles ou les pylônes électriques : cela participe à la dénaturation d’un paysage, avec une subtile nuance pour les éoliennes, où la symbolique positive écologique peut pour certains contrebalancer la perte de naturalité induite. Chez des personnes vivant dans un milieu plus urbanisé, le paysage naturel attire, car il change des habitudes de vie. Certains n’hésitent pas à qualifier un paysage de naturel pour peu qu’il contienne suffisamment de végétation, fusse une vaste étendue agricole dédiée à la monoculture. Chez des personnes vivant dans des milieux très ruraux par contre, on ne constate pas toujours la tendance inverse : même la petite ville voisine semble parfois trop urbanisée à leurs yeux pour y vivre. A leurs yeux, les paysages deviennent moins attractifs au fur et à mesure que la densité du bâti devient perceptible. Plus qu’une analyse du visuel, cette recherche montre également que les gens s’imaginent être dans le paysage, entendant les bruits ou ressentant une perte de convivialité à mesure que le paysage s’industrialise ou se remplit de maisons. [less ▲]

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See detailBaltic seagrass meadows as a sediment carbon sink
Jankowska, Emilia; Włodarska-Kowalczuk, Maria; Michel, Loïc ULg et al

Conference (2015, September 25)

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See detailOn generalized Hölder spaces
Kreit, Damien; Nicolay, Samuel ULg

Conference (2015, September 24)

We introduce generalized pointwise Hölder spaces as the point wise version of generalized uniform Hölder spaces. These last ones can be seen as a special case of generalized Besov spaces.

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See detailMedicinal plants, malaria and biotechnology
Frederich, Michel ULg; Jansen, Olivia ULg; Muganga, Raymond et al

Conference (2015, September 24)

The first part of the talk will be dedicated to the investigation of medicinal plants with the objective to identify new antimalarial treatments. According to the last World Malaria Report [1], there were ... [more ▼]

The first part of the talk will be dedicated to the investigation of medicinal plants with the objective to identify new antimalarial treatments. According to the last World Malaria Report [1], there were 584 000 deaths for 198 millions malaria cases worldwide in 2013. Particularly, the disease caused an estimated 437 000 African children died before their fifth birthday, still in 2013. Malaria is caused by a parasite, Plasmodium sp. and transmitted by Anopheles mosquitoes. The problem of parasite resistance towards common available medicines such as chloroquine, mefloquine, quinine, is increasing. In this context, the vegetal kingdom remains the main source of pharmacologically active compounds against this parasitic infection as attested by the famous quinine, isolated from Cinchona sp., artemisinin extracted from Artemisia annua and also atovaquone derived from lapachol found in several Bignoniaceae. All these substances are related to plants with traditional use against fever and malaria. Beside these well-known examples, various new antiplasmodial compounds are frequently discovered from Nature, particularly following an ethnopharmacological approach, as reviewed by several authors in recent years [2-6]. Then, the pharmacological and phytochemical study of plants from traditional pharmacopoeias can be of first interest not only to discover new antimalarial “lead compounds”, but also to valorize local vegetal species whose efficacy and safety would have been demonstrated in laboratory and by clinical investigations [7,8]. Some results obtained with Dicoma tomentosa from Burkina-Faso [9] and Terminalia mollis from Rwanda [10] will be presented. In the second part of the talk, two applications of biotechnology for the production of artemisinin and paclitaxel and then some works developed at the ‘Université de la Réunion’ will be presented. In the framework of this collaboration, Psiadia arguta, an endemic plant from Reunion Island, which is known to have cytotoxic, anti-plasmodial and anti-inflammatory properties, was subjected to micropropagation. The objective of the work was to compare the biological properties and the phytochemical composition of callus, vitroplants and acclimatized plants of Psiadia arguta [11]. 1. WHO, World Malaria Report 2014, December 2014, Geneva (http://www.who.int/malaria/publications/world_malaria_report_2014/en/). 2. Batista R, Silva Ade J Jr, de Oliveira AB: Plant-derived antimalarial agents: new leads and efficient phytomedicines. Part II. Non-alkaloidal natural products. Molecules 2009, 14:3037-72. 3. Bero J, Frédérich M, Quetin-Leclercq J : Antimalarial compounds isolated from plants used in traditional medicine. Journal of Pharmacy and Pharmacology 2009, 61:1401–1433. 4. Bero J and Quetin-Leclercq J: Natural products published in 2009 from plants traditionally used to treat malaria. Planta Medica 2011, 77:631-40. 5. Kaur K, Jain M, Kaur T, Jain R: Antimalarials from nature. Bioorganic & Medicinal Chemistry 2009, 17:3229–3256. 6. Nogueira CR and Lopes LMX: Antiplasmodial Natural Products. Molecules 2011, 16:2146-2190 7. Ginsburg H and Deharo E: A call for using natural compounds in the development of new antimalarial treatments – an introduction. Malaria Journal 2011, 10 (suppl. 1):S1 8. Willcox M, Graz B, Falquet J, Diakite C, Giani S, Diallo D: A “reverse pharmacology” approach for developing an antimalarial phytomedicine. Malaria journal 2011, 10(suppl1):S8 9. Jansen, O., Tits, M., Angenot, L., Nicolas, J.-P., De Mol, P., Nikiema, J.-B., & Frédérich, M : Anti-plasmodial activity of Dicoma tomentosa (Asteraceae) and identification of urospermal A-15-O-acetate as the main active compound. Malaria Journal 2012, 11, 289. 10. Muganga, R., Angenot, L., Tits, M., & Frédérich, M : In vitro and in vivo antiplasmodial activity of three Rwandan medicinal plants and identification of their active compounds. Planta Medica 2013, 80(6), 482-489. 11. Mahy Justine, Comparative study of biological activities and analysis of volatile compounds of Psiadia arguta in various cultures: vitroplants and acclimatized plants. Mémoire de M2, 2013, Université de Liège/Université de la Réunion. [less ▲]

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See detailVALIDATION RELEVANCE OF ANALYTICAL METHODS IN BIOTECHNOLOGY
Marini Djang'Eing'A, Roland ULg; Hubert, Philippe ULg

Conference (2015, September 24)

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See detailPerformances of a simple exhaust mechanical ventilation coupled to a mini heat pump: modeling and experimental investigations
Ransy, Frédéric ULg; Gendebien, Samuel ULg; Lemort, Vincent ULg

Conference (2015, September 24)

According to the European directive 2012/27/EU of October 2012 on energy efficiency, buildings represented 40 % of the EU’s final energy consumption in 2011. The major part of this energy consumption is ... [more ▼]

According to the European directive 2012/27/EU of October 2012 on energy efficiency, buildings represented 40 % of the EU’s final energy consumption in 2011. The major part of this energy consumption is due to the residential sector for space heating and domestic hot water production. Moreover, buildings are crucial to achieve the EU objective of reducing greenhouse gas emissions by 80-95 % by 2050 compared to 1990. In order to reduce these greenhouse gas emissions, retrofit measures regarding insulation and air-tightness have to be taken. However, such improvements of the building envelope lead to a relative increase in consumption related to ventilation. Indeed, according to Orme (2001), Roulet et al. (2001) and Fouih et al. (2012), the heating demand due to ventilation can reach more than 50 % of the total building heating demand for new and retrofitted buildings. To reduce the energy consumption due to ventilation, exhaust air heat pumps (EAHPs) can be used instead of the traditional heat recovery with an air-to-air heat exchanger. EAHPs recover heat from the exhaust air of the ventilation system to produce domestic hot water and space heating. According to Fehrm et al. (2002), this technology is already widely used in the northern countries such as Germany and Sweden. In fact, according to Fracastoro et al. (2010), efficiencies of EAHPs are higher than those obtained with outside air or geothermal heat pumps in certain conditions, whatever the climate location. Berg et al. (2010) have monitored three houses in Sweden equiped with exhaust air heat pumps. The seasonal performance factor (SPF) values were all within the range 1.4-1.7. This factor takes into account the energy consumption of the heat pumps and the auxiliary heating systems. A 17 kW exhaust air heat pump has also been tested by Mikola et al. (2014). The measured SPF for the heat pump only (without taking into account the auxiliary heating system) was about 2.9-3.4 in winter and 3 in the summer. Exhaust air heat pumps coupled with simple exhaust mechanical ventilation systems have many advantages compared to traditional balanced systems with heat recovery: • Only one fan is necessary and the duct system is simpler. Consequently, EAHPs are suitable for retrofitted buildings. • The heat pump can provide the whole part of the heating demand related to domestic hot water and 50 % of the heating demand related to space heating, according to Fracastoro et al. (2010). • The heat pump can also provide active cooling by inversing the refrigerating cycle. • The heat pump performance is high and remains constant with outdoor temperature changes since the temperature of the heat sink is constant (20°C). As a result, the system is cost-effective. • The system is compact, quiet and requires little maintenance. In the present paper, the energetic performances of an exhaust air heat pump are assessed through numerical and experimental studies. The thermal capacity of the machine is 1.5 kW when the inside air temperature is 20°C and the outside water temperature is 35°C. The heat pump is therefore ideally suited for new or retrofitted buildings. The system including a mechanical exhaust ventilation system and an exhaust air heat pump is first presented. Secondly, the heat pump model used afterwards to determine the heat pump seasonal performance factor is described. Thirdly, the model is calibrated to fit the measurement data. Finally, the heat pump model is coupled to a building model to determine the annual performance of the system. The system is compared to a traditional balanced ventilation system with heat recovery in terms of primary energy consumption, for different heating and DHW production systems (electric heater, heat pump, gas condensing boiler). [less ▲]

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See detailPerformances analytiques d’un biomarqueur : dialogue
CAVALIER, Etienne ULg

Conference (2015, September 23)

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See detailStratospheric HCl increasing again, caused by dynamic variability, driven by increased tropopsheric wave activity
Notholt, J; Mahieu, Emmanuel ULg; Pfloeger, F et al

Conference (2015, September 22)

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See detailAir-sea ice gases exchange: update of recent findings, outcomes from sea ice models, caveats and open questions
Delille, Bruno ULg; Zhou, Jiayun; Kotovitch, Marie ULg et al

Conference (2015, September 21)

There are growing evidences that sea ice exchanges climate gases with the atmosphere. We will rapidly present a state of the art of current large scale assessment of spring and summer uptake of ... [more ▼]

There are growing evidences that sea ice exchanges climate gases with the atmosphere. We will rapidly present a state of the art of current large scale assessment of spring and summer uptake of atmospheric CO2. We will challenge these assessments with 1) new evidence of significant winter CO2 release for winter experiments 2) new finding of the role of bubbles formation and transport within sea ice and 3) impurities expulsion derived from combined artificial ice experiment and modelling. Finally, comparison of air-ice fluxes derived from automated chamber and micrometeorological method and, mechanistic and box models show significant discrepancies that suggest that the contribution of sea ice to the air-ocean fluxes of CO2 remain an open question. We will also highlight that sea ice contribute to the fluxes of other gases as CH4 ,N2O and DMS [less ▲]

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See detailUse of Near Infrared Hyperspectral Imaging in studies on root systems
Eylenbosch, Damien ULg; Fernández Pierna, Juan Antonio; Fraipont, Guillaume ULg et al

Conference (2015, September 21)

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See detailPathways of recurrent high-grade squamous intraepithelial lesions of the cervix
Herfs, Michael ULg

Conference (2015, September 20)

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