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See detailLa recherche et la formation doctorales au XXIe siècle
Winand, Jean ULg

Conference (2013, December 04)

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See detail3D ERT monitoring of the reactivation of waste biodegradation with fresh leachate injection
Dumont, Gaël ULg; Robert, Tanguy ULg; Pilawski, Tamara et al

Conference (2013, December 04)

The aim of this study is to monitor (bio) physical processes occurring in a landfill. The experiment consists in injecting leachate towards a drain in unsaturated and not yet digested waste to reactivate ... [more ▼]

The aim of this study is to monitor (bio) physical processes occurring in a landfill. The experiment consists in injecting leachate towards a drain in unsaturated and not yet digested waste to reactivate (or activate) waste biodegradation. The target is the first 15 meters of the studied landfill subsurface. The visualization of the wet front arrival (short term effect) is crucial because we want to ensure that waste is entirely humidified to allow the reactivation of waste digestion. The second process is a long term effect consisting in the increase of the internal temperature of the landfill which is synonymous of the reactivation of biodegradation processes. We use 3D time-lapse ERT on a monthly basis to capture the decrease of electrical resistivity related to the increasing temperature. We also collect ground truth data, including distributed temperatures in a borehole to validate results. For short term effects, we monitored the wet front arrival with three 2D ERT profiles composing the 3D image, during an entire day. Preliminary results, corroborated by ground truth data, show that leachate flow in anisotropic (more rapid horizontally than vertically). So far, waste was completely humidified and slight changes of temperature occurred. [less ▲]

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See detailRay tracing enhancement for space thermal analysis: isocell method
Jacques, Lionel ULg; Masset, Luc ULg; Kerschen, Gaëtan ULg

Conference (2013, December 04)

The finite element method (FEM) is widely used in mechanical engineering, especially for space structure design. However, FEM is not yet often used for thermal engineering of space structures where the ... [more ▼]

The finite element method (FEM) is widely used in mechanical engineering, especially for space structure design. However, FEM is not yet often used for thermal engineering of space structures where the lumped parameter method is still dominant. Radiative exchange factors (REFs), used to calculate radiative thermal exchanges in space, are usually computed through Monte Carlo ray-tracing. Due to the large number of elements composing a FE model, the computation of the REFs is prohibitively expensive. In the frame of a global approach, several research axes will be investigated to reduce the computational effort of the REFs with FEM. The first one focuses on accelerating the convergence and enhancing the accuracy of the ray-tracing process to decrease the number of rays required to achieve a given accuracy. The developments of the new Isocell quasi-Monte Carlo ray tracing method are presented. Based on Nusselt’s analogy, the ray direction sampling is carried out by sampling the unit disc to derive the ray directions. The unit disc is divided into cells into which random points are then generated. The cells have the particularity of presenting almost the same area and shape. This enhances the uniformity of the generated quasi-random sequence of ray directions and leads to faster convergence. This Isocell method has been associated with different surface sampling to derive the REFs. The method is benchmarked against ESARAD, the standard thermal analysis software used in the European aerospace industry. Various geometries have been used. In particular, one entrance baffle of the Extreme Ultraviolet Imager (EUI) instrument developed at the Centre Spatial de Liège in Belgium is used. The EUI instrument of the Solar Orbiter European Space Agency mission and will be launched in a Sun-centered (0.28 perihelion) orbit in 2018. [less ▲]

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See detailDevelopment of anti-HPV lipoplexes for the treatment of cervical cancer
Lechanteur, Anna ULg; Furst, Tania ULg; Evrard, Brigitte ULg et al

Conference (2013, December 03)

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See detailA micro-meso model to predict van der Walls and capillary induced stiction in micro-structures
Hoang Truong, Vinh ULg; Noels, Ludovic ULg; Wu, Ling ULg

Conference (2013, December)

Undesirable stiction in MEMS results from the contact between surfaces and is due to the adhesive van der Waal and/or capillary forces, which become important for micro-structures. In this work, a micro ... [more ▼]

Undesirable stiction in MEMS results from the contact between surfaces and is due to the adhesive van der Waal and/or capillary forces, which become important for micro-structures. In this work, a micro-macro multi-scale approach is developed in order to predict possible stiction in MEMS structures At the lower scale, the unloading adhesive contact-distance curves of two interacting rough surfaces are established based on Maugis’ model extended herein to account simultaneously for the van der Waals and the capillary forces. The resulting unloading adhesive contact-distance curves are dependent on the material and surface properties -such as elastic modulus, surface energy- on the rough surfaces’ topography parameters -the standard deviation of asperities heights and the asperities’ density- and on the humidity level. At the higher scale, a beam finite element analysis is considered to determine the residual configuration due to the adhesive forces once contact happened. Toward this end, the adhesive contact-distance curve computed previously is integrated on the surface of the finite elements as a contact law. [less ▲]

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See detailOn the statistical assessment of small sample classification
Noirhomme, Quentin ULg; Lesenfants, Damien ULg; Gomez, Francisco et al

Conference (2013, December)

Classifiers start to be used in medical application to infer diagnosis. Their results are assessed through either a binomial or a permutation test. Distributions built from classification of random data ... [more ▼]

Classifiers start to be used in medical application to infer diagnosis. Their results are assessed through either a binomial or a permutation test. Distributions built from classification of random data with cross-validation, did not follow the theoretical binomial distribution, showing that binomial test was not conservative enough. A permutation test is thus recommended. [less ▲]

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See detailNon-Local Incremental-Secant Mean-Field-Homogenization of Damage-Enhanced Elasto-Plastic Composites
Wu, Ling ULg; Noels, Ludovic ULg; Adam, Laurent et al

Conference (2013, December)

An anisotropic gradient–enhanced continuum damage model is herein embedded in a mean–field homogenization (MFH) process for elasto-plastic composites. The homogenization procedure is based on the newly ... [more ▼]

An anisotropic gradient–enhanced continuum damage model is herein embedded in a mean–field homogenization (MFH) process for elasto-plastic composites. The homogenization procedure is based on the newly developed incremental secant mean-field homogenization formulation, for which the residual stress and strain states reached in the phases upon a fictitious elastic unloading are considered as starting point to apply the secant method. The mean stress fields in the phases are then computed using isotropic secant tensors, which are naturally used to define the Linear Comparison–Composite The resulting multi– scale model is then applied to study the damage process at the meso–scale of laminates, and in particular the damaging of plies in a composite stack. By using the gradient–enhanced continuum damage model, the problem of losing uniqueness upon strain softening is avoided. [less ▲]

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See detailProbabilistic model for MEMS micro-beam resonance frequency made of polycrystalline linear anisotropic material
Lucas, Vincent ULg; Wu, Ling ULg; Arnst, Maarten ULg et al

Conference (2013, December)

In order to ensure the accuracy of MEMS vibrometers, the first resonance frequency should be predicted at the design phase. However, this prediction cannot be deterministic: there is a scatter in the ... [more ▼]

In order to ensure the accuracy of MEMS vibrometers, the first resonance frequency should be predicted at the design phase. However, this prediction cannot be deterministic: there is a scatter in the reached value resulting from the uncertainties involved in the manufacturing process. The purpose of this work is to take into account these uncertainties of the microstructure and to propagate them up to the micro-beam resonance frequency. The objective is a non-deterministic model that can be used since the design stage. Towards this end a 3-scales stochastic model predicting the resonance frequency of a micro-beam made of a polycrystalline linear anisotropic material is described. Uncertainties are related to the sizes and orientations of the grains. The first part of the problem is a homogenization procedure performed on a volume which is not representative, due to the small scale of the problem inherent in MEMS. The method is thus non-deterministic and a meso-scale probabilistic elasticity tensor is predicted. This stage is followed by a perturbation stochastic finite element procedure to propagate the meso-scale uncertainties to the macro-scale, leading to a probabilistic model of the resonance frequency of the MEMS. [less ▲]

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See detailBiohydrometallurgy, a key for recyclng crtical metals?
Lambert, Fanny ULg

Conference (2013, December)

In Europe, recycling of end-of-life consumer goods appears as a strategy to secure raw materials supply and to preserve resources. Industrial processes exist to recycle a large number of metals (ferrous ... [more ▼]

In Europe, recycling of end-of-life consumer goods appears as a strategy to secure raw materials supply and to preserve resources. Industrial processes exist to recycle a large number of metals (ferrous metals, base metals and precious metals) but high technology metals, as some of the fourteen metals listed as critic in Europe, are currently not recycled from post-consuming applications. The PhD project focuses on the recycling of these high technology metals by an innovative process based on bio-hydrometallurgy. The main objective is the study of the possibility (technique and economic) to recover gallium from printed circuit boards. [less ▲]

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See detailCompétences durables et transférables, clé pour l'employabilité
Dujardin, Jean-Marie ULg

Conference (2013, December)

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See detailCURRENT CROWDING EFFECTS IN NANOSTRUCTURED SUPERCONDUCTORS
Silhanek, Alejandro ULg

Conference (2013, December)

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See detailInvestigating the Effects of Training and Techno-Pedagogical Support
Lecomte, Béatrice ULg; Van de Poël, Jean-François ULg; Verpoorten, Dominique ULg et al

Conference (2013, December)

This communication presents a quantitative-qualitative research conducted among 225 teachers and teaching assistants who have benefited from the education technologies training program provided by our ... [more ▼]

This communication presents a quantitative-qualitative research conducted among 225 teachers and teaching assistants who have benefited from the education technologies training program provided by our eCampus department at IFRES (University of Liege, Belgium) since 2011. The data collected are used to a) describe and characterize the public who attended these training sessions, b) identify the types of training programs chosen by the attendees, and c) to explore the influence of those sessions on the techno-pedagogical development of teachers. That effect is manifested by a change of mental representations or by "acting out" in terms of integrating technology into teaching practices. [less ▲]

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See detailHD 97658 and its super-Earth: Spitzer transit analysis and seismic modeling of the host star
Van Grootel, Valérie ULg; Gillon, Michaël ULg; Valencia, Diana et al

Conference (2013, December)

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See detailAlexander KLUGE / Gerhard RICHTER. L’ART CONTRE LE HASARD
Hagelstein, Maud ULg; Letawe, Céline ULg

Conference (2013, December)

Dans plusieurs de ses textes, A. Kluge affronte le problème du temps qui coule sans discontinuer avec des effets tantôt heureux tantôt désastreux. La formulation de ce problème implique presque toujours ... [more ▼]

Dans plusieurs de ses textes, A. Kluge affronte le problème du temps qui coule sans discontinuer avec des effets tantôt heureux tantôt désastreux. La formulation de ce problème implique presque toujours la référence au hasard – le cours hasardeux des choses qui fait qu’entre plusieurs indéterminations (plusieurs virtualités encore susceptibles d’êtres actualisées), à un moment, un seul événement est fixé de manière irréversible. Cette détermination hasardeuse et brutale a quelque chose de fatalement injuste : pourquoi le monde prend-il telle tournure (éventuellement catastrophique) plutôt que telle autre ? Pourquoi certains sont épargnés quand d’autres ne le sont pas ? Face à ce problème, Kluge nous donne les moyens – dans ses réflexions théoriques mais aussi par le dispositif pratique qu’il met au point dans ses œuvres – de repenser la fonction de l’art : les œuvres (visuelles ou littéraires) pourraient avoir pour vocation de dompter le flux fatal du temps, de suspendre l’ « emportance » du temps (pour citer la traduction de Vincent Pauval), en mettant « sous tension » nos représentations du monde et en y réintroduisant des indéterminations (des possibles) pour nous inviter à repenser l’histoire aussi bien dans sa terrible détermination que dans ses alternatives. Le travail entamé avec l’artiste allemand Gerhard Richter nous semble pouvoir être lu dans cette perspective. [less ▲]

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See detailEkphrasis in the Work of Lucian of Samosata – The Case of “The Centaurs Family”
Vanesse, Sylvain ULg

Conference (2013, December)

The literary and rhetoric process of Ekphrasis was used on numerous occasions in Ancient literature, especially by the author Lucian of Samosata. Because these descriptions of Works of Art combine ... [more ▼]

The literary and rhetoric process of Ekphrasis was used on numerous occasions in Ancient literature, especially by the author Lucian of Samosata. Because these descriptions of Works of Art combine literature and Art history, they allow scientists to choose either a philological or an iconographical study approach. Philologists obviously have studied these Ekphraseis so as to define their styles, shapes, and influences from the author, whereas Art historians have considered them as one of the rare source of information about the Ancient painting but have not always replaced them in their context of writing or taken a critical look at them. « The Centaur’s Family » picture, for example, which would have been painted by Zeuxis of Heraclea, will on the one hand allow us to highlight the problem of these two different analyses, and on the other hand to show how they can be combined to bring a new perspective, not only on this picture, but perhaps also on the other paintings described by Lucian of Samosata. [less ▲]

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See detailAttribution of Cysteine Connectivities in small toxins - New Prospects Based on Partial Oxidation/Reduction Experiments and Ion-Mobility Mass Spectrometry
Quinton, Loïc ULg; Massonnet, Philippe ULg; Echterbille, Julien ULg et al

Conference (2013, December)

Disulfide bonds are post-translational modifications often found in biological compounds and especially in animal toxins. Disulfide bonds participate in the formation of specific folding of peptides and ... [more ▼]

Disulfide bonds are post-translational modifications often found in biological compounds and especially in animal toxins. Disulfide bonds participate in the formation of specific folding of peptides and proteins, directly related to their biological activity. Cystein pairing determinations are primordial for the synthesis of chemical homologous displaying the same bioactivity than the natural compound. This task appears already difficult when the cysteine pairings have to be determined from large proteins. The combination of physical and chemical techniques such as NMR, enzymatic proteolysis, liquid chromatography and mass spectrometry, is needed to circumvent this difficulty. However, when the work concerns small compounds such as conotoxins, the problem is much more complex due to the low amount of available compound and to the lack of enzymatic cleavage sites between cysteines. In this study, we investigate the case of small peptides that contain two disulphide bonds. The idea is to determine the cystein pairings in such compounds by a chemical partial reduction (or oxidation) of the peptides, followed by the separation of the generated species by ion-mobility mass spectrometry, and their characterisation by tandem mass spectrometry. Up to now, we have investigated the partial reduction not only in solution (with DTT and TCEP) but also in the gas-phase (Electron transfer dissociation), and partial oxidation in solution (with 3-CPBA). The results demonstrate an unexpected complexity of the data, including low fragmentation ratios of peptides and disulfide scramblings. [less ▲]

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See detailL'iconologie des intervalles. Métavisuel et montages d'images fixes (Warburg)
Hagelstein, Maud ULg

Conference (2013, December)

Je vais tenter ici de reformuler ici les problématiques abordées durant ces journées à partir du champ disciplinaire spécifique de l’iconologie – que l’on peut plus ou moins situer à l’intersection de la ... [more ▼]

Je vais tenter ici de reformuler ici les problématiques abordées durant ces journées à partir du champ disciplinaire spécifique de l’iconologie – que l’on peut plus ou moins situer à l’intersection de la philosophie et de l’histoire de l’art (en tant que ses fondateurs, Aby Warburg puis Erwin Panofsky, ont construit les principes de la méthode dans le cadre d’une réflexion générale sur le symbolique, en dialogue avec la philosophie d’Ernst Cassirer, notamment). J’aborderai en introduction – très rapidement – les critiques récentes adressées à la méthode iconologique par la théorie de l’image contemporaine, critiques qui reposent globalement sur l’idée d’un déni du visuel et de sa spécificité (= ses moyens et sa logique propres) au profit du paradigme langagier – omniprésent dès qu’il s’agit de dégager le sens d’une image. Je repartirai notamment des propos d’un des principaux protagonistes de la Bildwissenschaft actuelle (= la science de l’image), G. Boehm. La critique de l’iconologie me semble parfois caricaturale, même si ces questions sont essentielles, et je voudrais essayer de la déstabiliser quelque peu en revenant aux sources de la méthode. Dans son ouvrage sur le métavisuel, dont MG m’a suggéré la lecture, Stefania Caliandro décrit le projet établi par Warburg d’un atlas d’images intitulé Mnemosyne comme une vaste entreprise d’explicitation, par l’image, de la fonction du visuel – idée que j’appuierai ici. En développant ce qu’il a lui-même appelé une « iconologie de l’intervalle », Aby Warburg suggère que les montages d’images, et la variété des agencements/séries dans lesquels elles peuvent être prises, contribuent à l’élaboration d’un méta-discours qui dépasse largement les significations établies portées par ces images individuellement. Loin de se contenter d’attribuer à des motifs visuels artistiques des significations déterminées, l’iconologie – dans cette version inaugurale – se donne pour objectif de faire apparaître (par l’image) la dynamique de transformation incessante qui anime les symboles de l’art. [less ▲]

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See detailEnergetical aspects of solar-like oscillations in red giants
Grosjean, Mathieu ULg; Dupret, Marc-Antoine ULg; Belkacem, Kevin et al

Conference (2013, December)

CoRoT and Kepler observations of red giants reveal very rich spectra of non-radial solar- like oscillations allowing us to probe their internal structure. The study of energetic aspects of these ... [more ▼]

CoRoT and Kepler observations of red giants reveal very rich spectra of non-radial solar- like oscillations allowing us to probe their internal structure. The study of energetic aspects of these oscillations is of great importance to predict the peak parameters in the power spectrum. The theoretical determination of lifetimes (or equivalently width) of the modes require non- adiabatic computations. Next, combined with a stochastic excitation model, we can also predict the height of the mode and finally obtain theoretical power spectra. Comparison between our theoretical predictions with observations give important constraint on red-giants models. Lifetimes and amplitudes of modes trapped in the envelope (e.g. radial modes) constrain the characteristics of the convective envelope and its time-dependent interaction with oscillations. Lifetimes of mixed-modes (mainly dipolar modes) strongly depend on mode trapping, allowing us to probe the core of red-giants. I will discuss under which circumstances mixed modes are detectable for a large variety of red-giant stellar models, with emphasis on the effect of the evolutionary status of the star (along the red-giant branch and during the He-burning phase) for a wide range of stellar masses (from 0.7 to 4 Msun ) on theoretical power spectra. [less ▲]

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See detailAsteroseismology of B stars with MESA
Thoul, Anne ULg

Conference (2013, December)

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Peer Reviewed
See detailDiversité des races de poules locales dans trois régions du monde: Bejaia (Algérie), le Nord du Vietnam et le Bas-Congo (République Démocratique de Congo)
Moula, Nassim ULg; Antoine-Moussiaux, Nicolas ULg; Philippe, François-Xavier ULg et al

Conference (2013, November 30)

La gestion des ressources génétiques animales est capitale pour le développement de filières de production durables. En production avicole, une érosion graduelle et régulière des ressources génétiques est ... [more ▼]

La gestion des ressources génétiques animales est capitale pour le développement de filières de production durables. En production avicole, une érosion graduelle et régulière des ressources génétiques est observée à l'échelle mondiale. Parmi les causes de cette érosion, on retrouve principalement un abandon progressif, volontaire ou contraint, de ces races par les éleveurs. D'autres facteurs aggravant sont les épidémies, les catastrophes naturelles, les conflits et la dégradation de l’habitat de ces animaux. Néanmoins, les races de poules traditionnelles contribuent significativement à la production de viande et d’œufs. Les races indigènes représentent plus de 80 % de la population de volaille mondiale. Cependant, la majorité de ces races n’ont pas été décrites et sont mal connues. La gestion efficace des ressources génétiques animales en général et aviaires en particulier nécessite une identification précise des races concernées, la connaissance des effectifs (taille des populations) et leur distribution géographique, permettant la caractérisation de leur habitat. L’objectif de ce travail est par conséquent de caractériser les races de poules locales dans trois régions du monde : Bejaia (Algérie), le Nord du Vietnam et le Bas-Congo (République Démocratique de Congo) par une description phénotypique, une évaluation des performances zootechniques et une étude des différentes pratiques d’élevage. Une grande diversité phénotypique a été révélée dans chaque région d'étude. Les objectifs d'élevage sont multiples (alimentaire, financier et socioculturel) et variables d’un pays à un autre. Les femmes et les enfants jouent un rôle important dans l'aviculture familiale, quoique variable entre les régions d'étude. Ainsi, les solutions visant à la promotion des races de poules locales doivent être adaptées à la spécificité de chaque contexte. [less ▲]

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See detailUn sociologue au pays du libre
Lejeune, Christophe ULg

Conference (2013, November 29)

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See detailIndoor Joinery and Furniture Made for Eighteenth-Century Houses in Liège (Belgium)
Gilles, Isabelle ULg

Conference (2013, November 29)

Though few eighteenth-century houses in Liège have conserved their original wooden furniture or fittings, archival research reveals that these elements constituted a key aspect of the domestic interior ... [more ▼]

Though few eighteenth-century houses in Liège have conserved their original wooden furniture or fittings, archival research reveals that these elements constituted a key aspect of the domestic interior. The present work draws largely on a series of public announcements known as Rendages proclamatoires which concerned property belonging to orphans sold by public auction, that exist. From 1697 to 1765, these sources provided descriptions of 257 houses situated within the city walls. The wooden furniture and fittings of eighteenth-century Liegerian houses can clearly be seen to be pertain to far more than the sole history of joinery: they also tell the story of Liege’s domestic living spaces in terms of social structure and cultural change. As such they eloquently illustrate the fact that it is only by taking into account the Old Regime’s conception of architecture as a total entity that we can today work towards establishing an increasingly just, coherent and complete understanding of ancient edifices. [less ▲]

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See detailDeterminanten bij bedrijfsartsen in hun aanpak van middelenmisbruik van werknemers
Lambrechts, M.C.; Ketterer, Frédéric ULg; Symons, Linda et al

Conference (2013, November 28)

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Peer Reviewed
See detailIntroduction / Conclusions
Saint-Amand, Denis ULg

Conference (2013, November 28)

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See detailIntroduction de la conférence inaugurale de J.-P. Bronckart "Dimensions praxéologiques et gnoséologiques de l'organisation des textes/discours" (27/11/2013) et aux deux journées d'études sur les "genres" en Langues et littératures modernes : didactique - linguistique, littérature, traduction (24 et 25 avril 2014)
Simons, Germain ULg; Letawe, Céline ULg

Conference (2013, November 27)

Cette introduction visait à présenter brièvement a) les objectifs de l'Entité de recherche structurelle du département, b) l'objet de recherche : les "genres", c) le programme des deux journées d'études ... [more ▼]

Cette introduction visait à présenter brièvement a) les objectifs de l'Entité de recherche structurelle du département, b) l'objet de recherche : les "genres", c) le programme des deux journées d'études dans les quatre grands domaines de recherche : littérature, linguistique, didactique et traduction et d) l'orateur de cette conférence inaugurale : J.P. Bronckart (Université de Genève). [less ▲]

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See detaildilemmas in cluster analysis
Sauvageot, Nicolas ULg

Conference (2013, November 27)

Cluster analysis is a set of multivariate procedures to detect natural groupings in data. The objective of those methods is to group a set of objects in such a way that objects in the same group (called ... [more ▼]

Cluster analysis is a set of multivariate procedures to detect natural groupings in data. The objective of those methods is to group a set of objects in such a way that objects in the same group (called cluster) are more similar to each other than to those in other groups. Organizing data into sensible groupings arises naturally in many scientific fields as psychology, biology, statistics, bioinformatics, marketing, and so on. However, the obtained solution is not unique and it strongly depends upon the analyst’s choices. Representation and normalization scheme, selection of distance measures and a clustering algorithm, choice of the number of clusters and their interpretations are all subjective choices which change the final output. Those decisions are mainly guided by the purpose of grouping, domain knowledge and the individual data set. Therefore, cluster validity assessment should be performed to evaluate the validity of the obtained clusters and to find the partitioning that best fits the underlying data. I provide a brief overview of clustering, summarize well known algorithms, and discuss the major challenges and key issues in performing clustering analysis. [less ▲]

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See detailDensification et qualité de vie : objectifs de la conférence et cadrage des travaux
Godart, Marie-Françoise; Halleux, Jean-Marie ULg; Hanin, Yves

Conference (2013, November 26)

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See detailElasto-inertial turbulence in polymeric flows
Terrapon, Vincent ULg; Dubief, Yves; Soria, Julio

Conference (2013, November 26)

The dynamics of elasto-inertial turbulence (EIT) is investigated numerically from the perspective of the coupling between polymer dynamics and flow structures. In particular, direct numerical simulations ... [more ▼]

The dynamics of elasto-inertial turbulence (EIT) is investigated numerically from the perspective of the coupling between polymer dynamics and flow structures. In particular, direct numerical simulations of channel flow with Reynolds numbers ranging from 1000 to 6000 are used to study the formation and dynamics of elastic instabilities and their effects on the flow. Based on the splitting of the pressure into inertial and polymeric contributions, it is shown that the trains of cylindrical structures around thin sheets of high polymer extension that are characteristics to elasto-inertial turbulence are mostly driven by polymeric contributions. [less ▲]

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See detailLa psychologie du travail au service de l'approche qualité
Nyssen, Anne-Sophie ULg

Conference (2013, November 26)

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See detailProduction de l’habitat et enjeux territoriaux : comment soutenir la transition vers un nouveau système de production pour l’habitat wallon ?
Halleux, Jean-Marie ULg

Conference (2013, November 26)

En Wallonie, la maison isolée demeure le type de logement le plus fréquemment construit. La construction résidentielle continue donc à se caractériser par un usage peu parcimonieux du sol. Pour autant ... [more ▼]

En Wallonie, la maison isolée demeure le type de logement le plus fréquemment construit. La construction résidentielle continue donc à se caractériser par un usage peu parcimonieux du sol. Pour autant, des signaux annonciateurs de la mise en place d’un système de production plus vertueux semblent se manifester, en lien avec la représentation croissante des logements collectifs et des logements mitoyens dans la production immobilière. Les traitements opérés afin de rendre compte de ces évolutions mettent en avant le rôle central de la disponibilité en zones d’habitat. En effet, ces tendances caractérisent surtout des régions où l’offre foncière constructible est en pénurie. La première partie de notre intervention sera focalisée sur ce sujet des relations entre la disponibilité en terrains et les modes de production du logement. En deuxième partie, nous présenterons les résultats d’une enquête menée auprès de ménages ayant choisi d’habiter un logement neuf. Les résultats de cette enquête témoignent du fait que la rareté foncière renforce l’acceptation des ménages pour les produits immobiliers de la maison jointive et de l’appartement. Par ailleurs, ils attestent de l’opportunité de développer une politique foncière active visant, d’une part, à renforcer la production de maisons mitoyennes à proximité des centres urbains et, d’autre part, à contrôler les développements de type Bimby. [less ▲]

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See detailTraitement médical des tendinopathies du genou
Kaux, Jean-François ULg

Conference (2013, November 23)

Detailed reference viewed: 83 (18 ULg)
See detailRéintroduction d'Aedes albopictus, une menace pour la Belgique? (Diptera: Culicidae)
Boukraa, Slimane ULg; Raharimalala, Fara Nantenaina ULg; Zimmer, Jean-Yves ULg et al

Conference (2013, November 23)

Actuellement, l’espèce Aedes albopictus Skuse est considérée comme le moustique le plus invasif dans le monde entier et l’un des plus importants vecteurs d’arbovirus (notamment chikungunya et dengue). En ... [more ▼]

Actuellement, l’espèce Aedes albopictus Skuse est considérée comme le moustique le plus invasif dans le monde entier et l’un des plus importants vecteurs d’arbovirus (notamment chikungunya et dengue). En Belgique, Ae. albopictus a été introduit pour la première fois en 2000 à Vrasene (Province de Flandre-Orientale), dans une entreprise de recyclage des pneus usagés en provenance des États-Unis et du Japon. Plusieurs autres inspections ont été effectuées (2001-2012) après ce premier rapport, mais aucun autre spécimen n’a été trouvé. L’espèce était considérée comme éliminée naturellement et aucune nouvelle introduction n’avait été signalée. Dans le cadre d'une étude de surveillance de moustiques réalisée dans plusieurs endroits à travers la Belgique en 2013, un adulte mâle d’Ae. albopictus a été capturé à l'aide d’un piège à CO2 à Vrasene dans la même entreprise de recyclage de pneus (51 ° 12'49 "N, 4 ° 11'37" E; juillet 2013). L’espèce a été confirmée par identification morphologique et moléculaire. Cette redécouverte d’Ae. albopictus ainsi que son absence durant les treize dernières années, démontrent sa réintroduction en Belgique via le commerce de pneus usagés. Une étude sur la survie et la dispersion de ce moustique en Belgique, ainsi que de son écologie dans les pays voisins pourrait fournir des indications importantes pour élucider davantage son caractère invasif et identifier les zones à haut risque. [less ▲]

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See detailQuand les traducteurs parlent de traduction. Ou le genre de la préface détourné
Letawe, Céline ULg

Conference (2013, November 23)

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See detailProtective effect of a new CHITOSAN BIOMATERIAL against the development of experimental osteoarthritis lesions in rabbit
Oprenyeszk, Frédéric ULg; Chausson, M; Maquet, V et al

Conference (2013, November 23)

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See detailEFFECTS OF CHONDROITIN SULFATE ON THE GENE EXPRESSION PROFILE IN THE INFLAMED SYNOVIAL MEMBRANE
Lambert, Cécile ULg; Dubuc, Jean-Emile; Montell, E et al

Conference (2013, November 23)

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See detailOleuropein or rutin consumption decreases the spontaneous development of OA in Hartley guinea pig
Sanchez, Christelle ULg; Horcajada, Marie-Noëlle; Membrez, Fanny et al

Conference (2013, November 23)

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See detailEFFECTS OF CHONDROITIN SULFATE ON THE GENE EXPRESSION PROFILE IN INTERLEUKIN-1Β STIMULATED SYNOVIAL FIBROBLAST CELLS CULTURES
Lambert, Cécile ULg; Dubuc, Jean-Emile; Montell, E et al

Conference (2013, November 23)

Detailed reference viewed: 4 (1 ULg)
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See detailComparaison de la qualité vocale chez des patients souffrant d’un cancer des cordes vocales classé T1a ayant suivi une résection endoscopique au laser ou une radiothérapie externe
Poncelet, Mélanie ULg; DEMEZ, Pierre ULg; PIRET, Yves et al

Conference (2013, November 22)

Thème général : le choix du traitement concernant les cancers glottiques à un stade précoce reste controversé. Les deux principaux traitements sont la chirurgie endoscopique au laser et la radiothérapie ... [more ▼]

Thème général : le choix du traitement concernant les cancers glottiques à un stade précoce reste controversé. Les deux principaux traitements sont la chirurgie endoscopique au laser et la radiothérapie. Nous nous sommes intéressée aux conséquences des traitements sur une fonction importante, à savoir la phonation. Hypothèse de recherche : la qualité vocale des patients ayant souffert d’une tumeur T1a du plan glottique varie en fonction du traitement reçu, à savoir une résection endoscopique au laser CO2 ou une radiothérapie. Matériel et méthodes : nous avons recruté 18 patients traités par cordectomie, 7 traités par radiothérapie et 31 sujets contrôles. Un bilan vocal recommandé par l’European Voice Society a été réalisé chez tous les participants. Ce bilan comprenait des mesures acoustiques, aérodynamiques et des mesures perceptives (évaluation par le sujet lui-même ainsi que par un jury naïf composé de 38 juges). Résultats : les sujets traités par cordectomie obtiennent un score au jitter plus élevé et une étendue fréquentielle réduite par rapport aux sujets contrôles. Leur temps maximum phonatoire est plus faible alors que leur Mean flow rate est plus élevé par rapport aux sujets contrôles. Leurs scores au VHI total ainsi qu’à l’échelle physique sont plus élevés. Au niveau des mesures acoustiques, aérodynamiques et perceptives nous n’obtenons pas de différence significative entre les patients traités par cordectomie et ceux traités par radiothérapie. On constate néanmoins que les voix des sujets traités par cordectomie ont tendance à être jugées par le jury comme moins altérées. Conclusion : notre étude ne permet pas d’affirmer la supériorité d’un des traitements en ce qui concerne la qualité vocale post-traitement. L’analyse perceptive réalisée par un jury naïf permet d’observer que les voix des sujets traités pas radiothérapie ont tendance à être jugées comme étant légèrement plus altérées que celles des sujets traités pas cordectomie. Bien que certains prolongements soient possibles, notre étude apporte néanmoins une évaluation multiparamétrique de la qualité vocale après un cancer des cordes vocales classé T1a et traité soit par cordectomie endoscopique au laser CO2 soit par radiothérapie externe. Elle est la première à utiliser un jury naïf dans l’évaluation perceptive de la qualité vocale. [less ▲]

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See detailLe développement langagier des enfants dysphasiques
Maillart, Christelle ULg

Conference (2013, November 22)

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See detailAccompagner les etudiants infirmiers en stage: enjeux et defis
Dury, Cécile ULg

Conference (2013, November 21)

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See detailHemicolectomie droite par laparoscopic
COIMBRA MARQUES, Carla ULg

Conference (2013, November 21)

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See detailClostridium difficile: an emerging zoonotic pathogen ?
Rodriguez Diaz, Cristina ULg; Taminiau, Bernard ULg; Avesani, Véronique et al

Conference (2013, November 21)

Clostridium difficile is an anaerobic, spore-forming bacterium that remains the main cause of nosocomial diarrhoea in humans after use of antibiotics. C. difficile has also been described in other ... [more ▼]

Clostridium difficile is an anaerobic, spore-forming bacterium that remains the main cause of nosocomial diarrhoea in humans after use of antibiotics. C. difficile has also been described in other environments outside of hospitals, such as soil, river and seawater samples (Pasquale et al., 2011) and in animals, in which it can also cause enteric disease (Songer and Anderson, 2006). The possibility of transmission of C. difficile pathogenic isolates between animals, environments and humans has been suggested (Janezic et al., 2012). In recent years, the interest in C. difficile in food and in food animals has increased, leading to studying animals as a possible reservoir and a potential risk for food borne infections linked to C. difficile. Studies in various countries have determined differences in the prevalence of C. difficile in animals just before slaughter (Houser et al., 2012; Rodriguez et al., 2012) as well as in retail meat (Houser et al., 2012). In addition, many types, including PCR-ribotype 078, are present in humans, animals and meat (Janezic et al.; Weese et al., 2009). The objective of this study was to evaluate the presence of C. difficile at the slaughterhouse and in retail meat. Intestinal and carcass samples were collected from pigs and cattle at a single slaughterhouse. Raw meat (beef and pork) was obtained from the retail trade. C. difficile was isolated in 1% and 9.9% of the pig and cattle intestinal contents and in 7.9% and 7% of cattle and pig carcass samples respectively. From retail meat, C. difficile was recovered from 2.3% of the beef samples and from 4.7% of the pork samples. A total of 21 different PCR-ribotypes were identified with a large percentage of types 078 and 014. This study confirms that animals are carriers of C. difficile at slaughter, and that carcass contamination occurs inside the slaughterhouse. Furthermore the results obtained also reveal the presence of toxigenic C. difficile in retail meat in Belgium with a predominance of isolates correlated with the PCR-ribotypes involved in human C. difficile infections. [less ▲]

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See detailUse of supercritical carbon dioxide to prepare drug-loaded polymer implants
Champeau, Mathilde; Tassaing, Thierry; Thomassin, Jean-Michel ULg et al

Conference (2013, November 20)

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See detailSwitching to the Dark Side: Repositioning of Polyglutamine Repeat Promotes Amyloid Fibril Formation by the Model Protein, β-Lactamase BlaP
Thorn, David ULg; Pain, Coralie ULg; Scarafone, Natacha et al

Conference (2013, November 20)

Background: The expansion of polyglutamine (polyQ) repeats is associated with an increased propensity of the protein to aggregate into amyloid fibrils. There are ten human proteins presently known within ... [more ▼]

Background: The expansion of polyglutamine (polyQ) repeats is associated with an increased propensity of the protein to aggregate into amyloid fibrils. There are ten human proteins presently known within which polyQ expansion above a threshold length, e.g. 35-50 residues, leads to ten distinct neurodegenerative disorders [1], the most well-known being Huntington’s disease. While repeat length, aggregation, and disease are well correlated, recent studies suggest the non-polyQ regions of these proteins can also play a significant role, both preventative and facilitative, in the aggregation process. With the aim of exploring this role in more detail, we have engineered chimeric proteins via the insertion of polyQ repeats of various length (23, 30, 55, 79 Q) into two sites of antibiotic resistance enzyme BlaP β-lactamase from Bacillus licheniformis 749/C [2]. Questions addressed: How does polyQ repeat position affect the structure, stability and aggregation of polyQ proteins? Methods: Aggregation kinetics determined by monitoring the decrease in soluble protein fraction over time. Aggregate morphology examined by transmission electron microscopy. Protein stability derived from thermal or chemical unfolding transitions monitored by far-UV CD and intrinsic fluorescence. Results and discussion: PolyQ insertion at either of the two positions led to a decrease in thermodynamic stability that was largely independent of polyQ length. Chimeras with polyQ insertions at position 216 were destabilised to a much greater extent than those with insertions at position 197. The reduced stability of the 216 chimeras was associated with an increased aggregation propensity: (i) the minimum polyQ length leading to aggregation was lower, and (ii) the aggregation rate was significantly higher than that observed by 197 chimeras with equivalent polyQ lengths. Remarkably, the two sites of polyQ insertion are indeed very similar, both residing within flexible loop regions between stable α-helices. Moreover, the 216 chimeras exhibited a higher aggregation propensity than their 197 counterparts even under denaturing conditions, suggesting the disparity between the two chimeras cannot be accounted for by structural differences alone. These findings highlight the strong and complex influence of the overall protein context on polyQ-mediated aggregation. The molecular basis for the observed changes in stability and aggregation propensity is the subject of on-going work. [less ▲]

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See detailBio-inspired polymers for the functionalization of surfaces by green processes
Detrembleur, Christophe ULg

Conference (2013, November 20)

Detailed reference viewed: 14 (1 ULg)
See detailLes acteurs de la carrière des femmes cadres : une analyse par catégories d'âge
Grodent, Françoise ULg

Conference (2013, November 20)

L'objectif de ce papier est d'identifier l'ensemble des acteurs qui interviennent dans la carrière ainsi que dans les choix professionnels des femmes cadres issues de trois catégories d'âge, à savoir les ... [more ▼]

L'objectif de ce papier est d'identifier l'ensemble des acteurs qui interviennent dans la carrière ainsi que dans les choix professionnels des femmes cadres issues de trois catégories d'âge, à savoir les moins de 35 ans, les [35-50] ans et les plus de 50 ans. Ce découpage en trois classes correspond tant aux générations (génération "Y", génération "X" et Baby-boomers) qu'aux catégories mobilisées en gestion, notamment en gestion des ressources humaines mais aussi dans les dispositifs légaux. On parle ainsi des jeunes (les juniors), des médiors et des seniors. L'idée principale est vraiment de voir si les femmes cadres, aux situations familiales multiples, gèrent leur carrière de manière individuelle et personnelle ou si elles tiennent compte de contraintes familiales, organisationnelles, amicales, etc. au moment de prendre des décisions relatives à leur travail. [less ▲]

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See detailReversibly cross-linked polymer micelle as smart drug dellivery device
Lecomte, Philippe ULg; Riva, Raphaël ULg; Cajot, Sébastien et al

Conference (2013, November 20)

Detailed reference viewed: 17 (5 ULg)
See detailOrganocatalyzed ring-opening polymerization of cyclic phosphate monomers
Clement, Benoît ULg; Vanslambrouck, Stéphanie ULg; Koole, Leo H. et al

Conference (2013, November 19)

Detailed reference viewed: 20 (8 ULg)
See detailLe rêve dans la Théorie du film ou l'épistémologie de l'exilé
Barbion, Sébastien ULg

Conference (2013, November 19)

Detailed reference viewed: 25 (6 ULg)
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See detailpH and redox responsive hydrogel and nanogels made from poly(2-ethyl-2-oxazoline)
Legros, Camille ULg; Gillet, Marie-Claire ULg; Tam, Michael et al

Conference (2013, November 19)

Detailed reference viewed: 13 (7 ULg)
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See detailFactive versus reported speech complements in English
Brems, Lieselotte ULg; Gentens, Caroline; Davidse, Kristin et al

Conference (2013, November 17)

Detailed reference viewed: 26 (1 ULg)
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See detailVitamine D et Allergie
GADISSEUR, Romy ULg

Conference (2013, November 16)

Detailed reference viewed: 29 (14 ULg)
See detailLa vitamine D, état des lieux et recommandations
CAVALIER, Etienne ULg

Conference (2013, November 16)

Detailed reference viewed: 25 (6 ULg)
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See detailLe plomb atmosphérique enregistré dans les stalagmites de Han-sur-Lesse
Allan, Mohammed ULg; Verheyden, sophie

Conference (2013, November 16)

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See detailL’Afrique et la science impériale britannique dans une phase de transition: une étude de cas de l’expédition au Congo en 1816 sous la direction de James Hingston Tuckey
Vandersmissen, Jan ULg

Conference (2013, November 16)

This paper fits in a broader research project funded by the Belgian F.R.S.-Fonds national de la Recherche scientifique. It is entitled: Africa in the “science policies” of France and Great Britain from ... [more ▼]

This paper fits in a broader research project funded by the Belgian F.R.S.-Fonds national de la Recherche scientifique. It is entitled: Africa in the “science policies” of France and Great Britain from the eighteenth to the mid- nineteenth century: the scholarly background of the Scramble. This general project aims at completing in an original way recent studies on the interactions between the “New Science” derived from the Scientific Revolution and the building of colonial empires in the Atlantic area from the Enlightenment to the apogee of the first Industrial Revolution. Its objective is to investigate how in this period Africa has become a scientific object in its own right for the colonial administrations of France and Great Britain. Botanical knowledge (industrial plants, food crops and medicinal herbs) that originated in Africa was first applied in the plantations of slave economies in the Caribbean and North America. It was increased with knowledge about the geography and natural history of the continent’s interior through a revival of exploration in Africa itself. The project aims to relate the increased interest from scholars for Africa to the intensification of economic and military competition between the powers. It also wants to demonstrate how a more precise knowledge of the African terrain influenced the ways in which the governments of both countries have integrated colonial expertise in a complex science policy adapted to the specific needs of the two states. In this paper I will focus on the British side of the spectrum. I will investigate the changing British attitude towards Africa in the early nineteenth century through a case study of an expedition to the River Congo organized in 1816. Although this expedition ended in disaster (a majority of the members died in the course of the undertaking), it offers a series of useful examples that help to illustrate the transformation of British science policies under the pressure of competition with the French. Thus, it is my aim to show how Great Britain in the face of state-oriented French science has abandoned its policy of informal relationships and started to encourage its administration and scientific institutions to intervene more directly in exploration. Crucial in this evolution was the way in which the Admiralty absorbed the scholarly input of a number of learned societies and institutions, such as the Royal Society, the British Museum or the so-called “African Association” – the latter combining both scientific and commercial objectives. Thus the expedition illustrates the transition from Late Enlightenment “Banksian” exploration, inspired by the omnipotent science organizer Sir Joseph Banks (1743-1820), towards a more thorough imperial design of exploration under the command of Sir John Barrow (1764-1848). Already since the French conquest of Egypt, “scientific” expeditions relied on the collaboration between learned networks and the military, an example that would be copied later in Algeria. At the British side, it was the Admiralty that strengthened its grip on exploration. Tuckey’s expedition illustrates very well the amplification of operations, the more direct intervention by the government, and the growing importance of the commercial agendas of science. I will focus here on the interaction between the Admiralty and the learned societies with regard to the composition of the instruction text given to the leader of the expedition on the eve of his departure, on the specific choice of the area he had to explore (related to the “Niger question”), on the practical organization (e.g. the development of special steam engines by the engineer Watt, the scientific equipment offered with the help of the British Museum, etc.), on the choice of the scientists who formed a real team of experts (e.g. Christen Smith, John Cranch, etc.), on the collection of scientific data and their integration in collections in Britain, on the presentation of the expedition’s results in a published report entitled Narrative of an expedition to explore the river Zaire, usually called the Congo, in South Africa, in 1816, under the direction of Captain J. K. Tuckey, R.N., (London, 1818), and finally, on the circulation of these results in the rest of Europe due to the translation of the report in Dutch and French. [less ▲]

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See detailQuelles activités pour nos seniors souffrant de maladie de la mémoire ?
Adam, Stéphane ULg

Conference (2013, November 16)

Detailed reference viewed: 126 (19 ULg)
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See detailFilamentous fungi in water distribution systems: what is the risk?
Hayette, Marie-Pierre ULg

Conference (2013, November 14)

Detailed reference viewed: 17 (2 ULg)
See detailObservations sur la forme, l'état du support et la mise en page du P.Vat.gr. 11
Carlig, Nathan ULg

Conference (2013, November 14)

Detailed reference viewed: 9 (1 ULg)
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See detailFiscalité européenne : soixante ans de hauts et de bas
Richelle, Isabelle ULg

Conference (2013, November 14)

La fiscalité ne peut être ignorée dans la construction européenne d’un marché intérieur unique. Cependant, la fiscalité étant un des attributs essentiels de la souveraineté étatique, les Etats membres ... [more ▼]

La fiscalité ne peut être ignorée dans la construction européenne d’un marché intérieur unique. Cependant, la fiscalité étant un des attributs essentiels de la souveraineté étatique, les Etats membres sont particulièrement réticents à délaisser de leurs compétences en ce domaine. Elle n’apparaît donc pas comme un élément-clé de cette construction. Pourtant, dès le Traité de Rome, des choix stratégiques sont opérés, qui vont peu à peu conduire à l’harmonisation de pans entiers de la fiscalité. Si certaines avancées résultent de l’action politique, d’autres progrès seront plus tard le fait des contribuables. L’émergence d’une fiscalité européenne est donc le résultat d’un processus évolutif et interactif impliquant – à des degrés divers – les institutions européennes, les Etats membres et les contribuables. Cette construction connaît cependant des limites, qui sont d’autant plus durement ressenties que la fiscalité prend de plus en plus d’importance, par rapport à d’autres matières, au fur et à mesure de la réalisation du marché intérieur. [less ▲]

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See detailLe dossier papyrologique de Favorinos d'Arles
Marganne, Marie-Hélène ULg

Conference (2013, November 14)

La mise en série et la comparaison des trois papyrus littéraires grecs en relation avec Favorinos révèlent maints points communs : même datation au IIIe siècle, même utilisation d'un support d'écriture de ... [more ▼]

La mise en série et la comparaison des trois papyrus littéraires grecs en relation avec Favorinos révèlent maints points communs : même datation au IIIe siècle, même utilisation d'un support d'écriture de réemploi, même type d'écriture, informelle ou cursive, et même contexte de production ou d'utilisation. Provenant, l’un, de la Marmarique, et un autre, sûrement, d'Oxyrhynchus, ils attestent la connaissance de l'auteur arlésien (c. 80-150/160), dans la chôra égyptienne au sens large, moins d'un siècle après sa mort, probablement dans le cadre particulier des intérêts liés à la rhétorique et à son enseignement ou son apprentissage ou sa pratique. [less ▲]

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See detailDo recent West African rainfall variations really impact the livestock in the Sahel?
Ozer, Pierre ULg

Conference (2013, November 14)

Detailed reference viewed: 13 (0 ULg)
See detailVulnérabilité du patient âgé (en partenariat avec le Professeur A. BENETOS)
Petermans, Jean ULg

Conference (2013, November 14)

Detailed reference viewed: 44 (6 ULg)
See detailAssessing the vulnerability of sites in the East African Rift Valley to natural hazards: case study of Bujumbura, Burundi
Nibigira, Léonidas ULg; Havenith, Hans-Balder ULg; Dewals, Benjamin ULg et al

Conference (2013, November 13)

Due to the geomorphologic, structural and climatic context, the East African Rift Valley is prone to many natural hazards. The locally high density of the population contributes to related risk. As a ... [more ▼]

Due to the geomorphologic, structural and climatic context, the East African Rift Valley is prone to many natural hazards. The locally high density of the population contributes to related risk. As a result, the impacts on the habitat and infrastructures are constantly increasing. This work is based on a case study near the city of Bujumbura, which, for decades, has been affected by severe floods. Based on a study focusing on one of its rivers, the river Ntahangwa, this work tries to answer some questions related to the potential causes and ways of prevention and management of flood risk. The analysis is based on hydrological considerations while having a look at the possible mutual influences between these hydrological risks and geodynamic hazards. The methodology uses rainfall, geographic, demographic, topographic, and elevation data. Hydraulic modeling reveals the extent of the flood hazard according to its likelihood of occurrence and its sensitivity to geodynamic disturbances. This led us to propose solutions and related prevention/remediation measures. Considering the vulnerability of the population, it is clear that a change of people’s behavior is needed to reduce the total risk they’re exposed to, both with respect to the choice of construction areas and to all kinds of activities related to rivers exploitation. [less ▲]

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See detailDes activités pour nos aînés en institution? Oui, mais pas n’importe lesquelles!
Adam, Stéphane ULg

Conference (2013, November 13)

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See detailEUTHANASIE ET DEMENCE
Barthélemy, Nicole ULg; DAMAS, François ULg; ALLEPAERTS, Sophie ULg et al

Conference (2013, November 13)

Detailed reference viewed: 18 (1 ULg)
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See detailSAHBNET, An Accessible Surface-Based Elastic Network to Insert a Protein in a Complex Lipid Membrane
Dony, Nicolas ULg; Crowet, Jean-Marc ULg; Joris, Bernard ULg et al

Conference (2013, November 11)

Study of membrane proteins have become one of the most challenging fields in biology. Solving their structure is one important step toward the understanding of their physiological activity but despite the ... [more ▼]

Study of membrane proteins have become one of the most challenging fields in biology. Solving their structure is one important step toward the understanding of their physiological activity but despite the recent advances in membrane protein crystallization, it represents less than 1 % of the entries in the Protein Data Bank. Therefore, calculation methods to study membrane proteins are helpful to complement experimental studies and fill the gap between the information obtained from the sequence and/or structure, the experimental results and the biological activity. Molecular Dynamics is a method of choice for membrane simulations and the rising of coarse-grained forcefields has opened the way to longer simulations with reduced calculations times. However, these approaches have two main drawbacks, the preparation of complex systems and the preservation of the 3D protein structure, which is not trivial in coarse grained approach. To circumvent these problems, we propose to use a modified version of the Gromacs tool genbox to easily insert lipids and a network based on hydrogen bonds and accessible surface to maintain the protein 3D structure. This protocol is available through a website (gcgs.gembloux.ulg.ac.be). [less ▲]

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See detailInfinite Depth: du Movie Ride à la 3D relief, l'expérience de la profondeur.
Thonon, Jonathan ULg

Conference (2013, November 10)

Detailed reference viewed: 12 (1 ULg)