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See detailPrevalence of frailty among nursing home, according to different operational definitions.
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; GILLAIN, Sophie ULg et al

in Osteoporosis International (2016, April), 27(Supplement 1), 216-217

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See detailIs isokinetic exercise dangerous for the heart?
Le Goff, Caroline ULg; Kaux, Jean-François ULg; Cavalier, Etienne ULg et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(suppl. 1 No. 2), 457

INTRODUCTION: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in ... [more ▼]

INTRODUCTION: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in order to perform these very intensive exercises; otherwise an acute myocardial dysfunction could theoretically appear in predisposed patients. PURPOSE: Our study aimed to observe the cardiovascular impact (by biological point of view) of maximal intense isokinetic eccentric and concentric protocols performed by a population of sedentary young men. METHOD: Resting (T0) and post-exercise (just after (T1), 3 hours (T2) and 24 hours after the exercise (T3)) blood samples were taken in 2 populations of young sedentary men: 12 subjects (22.5±1.15 yo) for the eccentric protocol and 18 subjects (22.4±2.6 yo) for the concentric protocol. These subjects performed an intense maximal isokinetic exercise of the quadriceps muscles involving 30 knee flexions–extensions for each leg. We evaluated markers of cardiovascular risk (highly sensitive troponin T (hs-TnT), N-Terminal Brain natriuretic peptide (NT-proBNP), myoglobin (MYO)), of inflammation (highly sensitive C-reactive protein (hsCRP)), muscle damage (creatine kinase (CK)) and of oxidative stress (myeloperoxidase (MPO), lipidic peroxides (POXL), reduced (GSH) and oxidised glutathione (GSSG)). Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: All the physiological parameters measured presented statistically significant changes. For the eccentric exercise, no significant modification in cardiac (NT-proBNP, hs-TNT) and inflammation (hsCRP) biomarkers was observed. However, a significant increase for CK (T3), MYO (T2), MPO (T1), POXL (T1), GSSG (T3) and ratio GSH/GSSG (T2-T3) was shown. For the concentric exercise, the results showed significant increases for the CK (T1-T2-T3), MYO (T1-T2), GSH/GSSG (T1). Evolutionary trends were also observed for the following biomarkers: NT-proBNP (T1-T2-T3), MPO (T2), and GSSG (T4). DISCUSSION and CONCLUSIONS: No modification in cardiac biomarkers was observed after the maximal eccentric isokinetic exercise but some variations can be observed for these biomarkers after the concentric exercise. However, these changes do not exceed the reference values in healthy subjects. We were thus able to prove that the exercise could be performed without any risk to cardiac function in young sedentary subjects. Nevertheless, a significant level of oxidative stress was induced by both exercises. [less ▲]

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See detailThe O2(a1Δ) Venus nightglow intensity: internal versus solar activity control
Soret, Lauriane ULg; Gérard, Jean-Claude ULg

Conference (2016, April)

Introduction: The O2(a1Δg) Venus nightglow emission at 1.27 μm occurs in the atmospheric region governed by the subsolar to antisolar circulation. Several studies showed that the intensity of this ... [more ▼]

Introduction: The O2(a1Δg) Venus nightglow emission at 1.27 μm occurs in the atmospheric region governed by the subsolar to antisolar circulation. Several studies showed that the intensity of this emission is highly variable on a timescale of hours. Here, we study the possible correlation between the solar flux and the O2 infrared emission using VIRTIS-VEx spectral images at 1.27 μm that has been predicted to exist by theVTGCM model calculations by Bougher and Borucki(1994). VIRTIS data: Using the entire VIRTIS-M-IR nadir database, Soret et al. (2014) generated seven statistical maps of the O2(a1Δg) emission, each containing 500 observations. The purpose was to analyze the location of the brightest spot of the emission and its variations over time. Here, we analyze the intensity of the emission over time. Several methods have been used by Soret et al., (2015) to do so (evolution of the emission maximum, evolution of the average intensity, …) Here we present the results of a new analysis using a masking technique to calculate the time evolution of the nightglow brightness. However, none of them follow the same trend over time. Solar flux data: We now focus on solar flux variations in the time of VIRTIS observations (between May 2006 and October 2008), which were collected during a deep solar minimum. We use the SOHO-CELIAS/SEM (Judge et al., 1998) EUV daily average full solar disk fluxes at 1 AU between 0.1 and 50 nm available from the Space Sciences Center of the University of Southern California. EUV0.1–50 daily average fluxes decrease from 2.6 in May 2006 to 1.9 in October 2008 at the Earth. These values have been adapted to Venus by taking into account the distance from the Sun to the planet, but also the shift in date, considering the difference in solar longitude of the two planets. Values at Venus vary from 4.4 to 3.4, which corresponds to a decrease of 10.4% of the solar flux at Venus compared to a complete solar cycle (ranging from 13.5 to 3.9) Comparison of VIRTIS and SEM datasets: The linear correlation coefficient between the solar flux and the intensity peak is found to be 0.62, which expresses the global decreasing trend for both quantities. This coefficient is not higher because internal variations of the two studied variables do not occur simultaneously. More significantly, the correlation coefficient between the solar flux and the averaged intensities is found to be 0.35, meaning that no relation-ship exists between the O2(a1Δg) brightness and the solar activity. Conclusions: Contrary to the VTGCM calculations, we do not observe here a correlation between the O2(a1Δg) brightness and the solar flux. However, VIRTIS data were acquired during a deep solar minimum and, more importantly, during a relatively stable phase of the solar activity. A high level of variability of the O2(a1Δg) emission has been detected in the same dataset from day to day though (Hueso et al., 2008; Soret et al., 2014). It thus appears that the variability is more controlled by internal than external conditions: transport appears to play a major role in the nightglow emissions than the solar activity eventually does. This conclusion is at least valid for solar minimum conditions. A space mission with global imaging capabilities over an entire solar cycle would definitely allow determining the relative role played by solar activity and internal factors. [less ▲]

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See detailUncertainty quantification in profile Hidden Markov Models (pHMM)-based activity sequences characterization
Saadi, Ismaïl ULg; Liu, Feng; El Saeid Mustafa, Ahmed Mohamed ULg et al

Poster (2016, April)

Recently, Liu et al. (2015) proposed a method to characterize activity sequences stemming from activity-travel diaries. The framework is structured as follows: from an extracted set of activity sequences ... [more ▼]

Recently, Liu et al. (2015) proposed a method to characterize activity sequences stemming from activity-travel diaries. The framework is structured as follows: from an extracted set of activity sequences, (a) the occurrence probabilities of the different activities are determined as well as their sequential order for aligning the activity sequences. Then, (b) profile Hidden Markov Models (pHMM) are defined based on the previous output. This technique is interesting given the fact that it is also able to include the irregular activities and, as a result, their derived trips. In this context, thinking about integration with an agent-based micro-simulation model requires, as a preliminary step, an uncertainty quantification analysis in order to measure the variability of the outcome. This approach is all the more necessary when agent-based micro-simulation is used to predict mid- and long-term system states. [less ▲]

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See detailCompact handheld low-cost biosensor platform for remote health monitoring
Hastanin, Juriy ULg; Lenaerts, Cedric ULg; Gailly, Patrick ULg et al

in Proceedings of SPIE; SPIE 2016 Photonics Europe (2016, April)

In this paper, we present an original concept of plasmonic-related instrumentation platform dedicated to diagnostic biosensing tests out of the laboratory. The developed instrumental platform includes ... [more ▼]

In this paper, we present an original concept of plasmonic-related instrumentation platform dedicated to diagnostic biosensing tests out of the laboratory. The developed instrumental platform includes both disposable one-use microfluidic affinity biochip and compact optical readout device for biochip monitoring involving mobile Internet devices for data processing and communication. The biochip includes both microfluidic and optical coupling structures formed into a single plastic slab. The microfluidic path of the biochip operates in passive capillary pumping mode. In the proof-of-concept prototype, we address specifically the sensing format involving Surface Plasmon Resonance phenomenon. The biochip is plugged in the readout device without the use of an index matching fluid. An essential advantage of the developed biochip is that its implementation involves conventional hot embossing and thin film deposition process, perfectly suited for mass production of low-cost microfluidic biochip for biochemical applications. [less ▲]

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See detailEfficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys.
Rannou, F.; Maheu; Reginster, Jean-Yves ULg

in Osteoporosis International (2016, April), 27(supplement 1), 66

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See detailMuscular and functional tridimensional analysis after hamstring strain
Paulus, Julien ULg; DELVAUX, François ULg; Schwartz, Cédric ULg et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(2), 263

Introduction The muscle injury, and more especially the hamstring strain, account for a large proportion of explosive top athletes injuries [1-3]. The subsequent down-time period has some sports and ... [more ▼]

Introduction The muscle injury, and more especially the hamstring strain, account for a large proportion of explosive top athletes injuries [1-3]. The subsequent down-time period has some sports and financial negatives consequences for the athlete, his team and/or his club [4, 5]. Despite the rehabilitation before return to play and prevention program, hamstring reinjury rates are still high (26% of all injuries) [6] and it's commonly accepted that a second injury is more severe than a first episode [2]. A more functional test could help the clinician in the return to play process decision to reduce the muscle injuries hamstring relapse. Purpose The aim of our methodology is to analyze, after medical clearance to resume sports activities, for athletes who suffered from grade II/III hamstring muscle strain, the biomechanics of the lower limbs during an explosive jump task. Method After (7,3±0,7 weeks) a grade II or III hamstring muscle tear, eight men (25±5,9 years), without past lower limb major injury, performed: - an isokinetic test (knee maximal flexion-extension in concentric at 60°.s-1 and 240°.s-1 and knee maximal flexion in eccentric at 30°.s-1); - a tridimensional biomechanics analysis of (bipodal and unipodal) squat jump and counter movement jump with Codamotion® system and Kistler® multicomponent force plates. Results A muscular lateral strength imbalance (±10% with p-value < 0,02) has been identified on the hamstring in concentric and eccentric by means of isokinetic testing, with the healthy side stronger than the pathologic. The main statistical significant outcome in the biomechanics analysis is the lower knee angle (±12% with p-value < 0,02) at the low point before the concentric pushing phase of the unipodal CMJ for the healthy leg than to the other one whereas there's no difference between both legs in an equivalent healthy population. Discussion & conclusion The tridimensional analysis appears to be complementary, not redundant, with the isokinetic strength testing due to the different nature of their informations obtained. It could be integrated in the return to play process decision expected the potentially interesting information about the player's biomechanics that it provides. References 1. Ekstrand, J., M. Hagglund, and M. Walden, Epidemiology of muscle injuries in professional football (soccer). Am J Sports Med, 2011. 39(6): p. 1226-32. 2. Ekstrand, J., M. Hagglund, and M. Walden, Injury incidence and injury patterns in professional football: the UEFA injury study. Br J Sports Med, 2011. 45(7): p. 553-8. 3. Lopez, V., Jr., et al., Profile of an American amateur rugby union sevens series. Am J Sports Med, 2012. 40(1): p. 179-84. 4. Price, R.J., et al., The Football Association medical research programme: an audit of injuries in academy youth football. Br J Sports Med, 2004. 38(4): p. 466-71. 5. Verrall, G.M., et al., Assessment of player performance following return to sport after hamstring muscle strain injury. J Sci Med Sport, 2006. 9(1-2): p. 87-90. 6. Brooks, J.H., et al., Incidence, risk, and prevention of hamstring muscle injuries in professional rugby union. Am J Sports Med, 2006. 34(8): p. 1297-306. [less ▲]

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See detailNon-invasive vagus nerve stimulation with the gammaCore® in healthy subjects: is there electrophysiological evidence for activation of vagal afferents ?
Schoenen, Jean ULg; NONIS, Romain ULg; D'Ostilio, Kevin ULg et al

Poster (2016, April)

Abstract: Background Non-invasive vagus nerve stimulation (nVNS) with the gammaCore® improves migraine and cluster headache. Animal experiments suggest that nVNS acts via stimulation of vagal afferents ... [more ▼]

Abstract: Background Non-invasive vagus nerve stimulation (nVNS) with the gammaCore® improves migraine and cluster headache. Animal experiments suggest that nVNS acts via stimulation of vagal afferents, but proof in humans is lacking. Vagal somatosensory evoked potentials (vSEP) are identified after invasive VNS or transcutaneous stimulation of auricular vagal branches, but late components could be muscle artifacts. Objective To search in healthy volunteers for reliable vSEP during nVNS with the gammaCore® Methods In 12 healthy subjects (7males) evoked potentials were recorded at A1/A2 (ref Cz) and C3/C4 (ref F3/F4) during 2-minute stimulation over left/right cervical vagus nerve with the gammaCore® (25Hz, 6-24V) and during stimulation over the inner tragus with a monopolar stimulator (2Hz, 50 stimuli, mean intensity 8mA). Results We identified 3 reproducible peaks P1, N1, P2 in 10 patients on the side of the gammaCore® stimulation at mean latencies of 2.05ms, 5.20ms and 9.13ms. P1-N1 amplitude increased significantly (p<0.01) with increasing voltage from 0.04μV to 0.52μV (C3/C4) and from 0.13µV to 2.04μV (A1/A2) respectively at 10V and 30V. Inner tragus stimulation elicited P1, N1, P2 peaks with shorter mean latencies (2.21ms, 3.72ms, 5.71ms) and a mean P1-N1 amplitude (A1/A2) of 5.0µV. When the gammaCore® was placed over the sternocleidomastoid muscle, there were no reproducible evoked potentials. Conclusion Non-invasive transcutaneous stimulation of the cervical vagus nerve with the gammaCore® elicits evoked potentials similar to those found with implanted electrodes or stimulation of Arnold’s nerve in the outer ear. The gammaCore®-evoked potentials increase in amplitude with stimulation intensity and disappear when the stimulator is positioned over neck muscles, suggesting that they are not muscle artifacts. Their short latency is compatible with their generation at the level of the foramen jugulare. The therapeutic effects reported with the gammaCore® in primary headaches can thus be mediated by genuine activation of vagus nerve afferents. [less ▲]

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See detailIdentification of nonlinear frequency responses and bifurcations from experimental data
Noël, Jean-Philippe ULg; Gourc, Etienne ULg; Grappasonni, Chiara ULg et al

in Actes de CFA/VISHNO 2016 (2016, April)

The objective of the paper is to obtain the frequency response curves of nonlinear mechanical systems from broadband testing. The proposed approach consists in coupling an identification method with a ... [more ▼]

The objective of the paper is to obtain the frequency response curves of nonlinear mechanical systems from broadband testing. The proposed approach consists in coupling an identification method with a continuation method. Specifically, the frequency-domain nonlinear subspace identification (FNSI) method is first used to derive an experimental model of the structure in state-space from broadband measurements. The harmonic balance method coupled with arclength continuation then utilizes this experimental model to compute the frequency response curves of the system. The method is demonstrated using a numerical example. [less ▲]

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See detailUnderground Pumped Storage Hydropower using abandoned open pit mines: influence of groundwater seepage on the system efficiency
Pujades, Estanislao ULg; Bodeux, Sarah ULg; Orban, Philippe ULg et al

Poster (2016, April)

Pumped Storage Hydropower (PSH) plants can be used to manage the production of electrical energy according to the demand. These plants allow storing and generating electricity during low and high demand ... [more ▼]

Pumped Storage Hydropower (PSH) plants can be used to manage the production of electrical energy according to the demand. These plants allow storing and generating electricity during low and high demand energy periods, respectively. Nevertheless, PSH plants require a determined topography because two reservoirs located at different heights are needed. At sites where PSH plants cannot be constructed due to topography requirements (flat regions), Underground Pumped Storage Hydropower (UPSH) plants can be used to adjust the electricity production. These plants consist in two reservoirs, the upper one is located at the surface (or at shallow depth) while the lower one is underground (or deeper). Abandoned open pit mines can be used as lower reservoirs but these are rarely isolated. As a consequence, UPSH plants will interact with surrounding aquifers exchanging groundwater. Groundwater seepage will modify hydraulic head inside the underground reservoir affecting global efficiency of the UPSH plant. The influence on the plant efficiency caused by the interaction between UPSH plants and aquifers will depend on the aquifer parameters, underground reservoir properties and pumping and injection characteristics. The alteration of the efficiency produced by the groundwater exchanges, which has not been previously considered, is now studied numerically. A set of numerical simulations are performed to establish in terms of efficiency the effects of groundwater exchanges and the optimum conditions to locate an UPSH plant. [less ▲]

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See detailUne généralisation du triangle de Pascal et la suite A007306
Stipulanti, Manon ULg

Conference (2016, March 25)

We introduce a generalization of Pascal triangle based on binomial coefficients of finite words. These coefficients count the number of times a word appears as a subsequence of another finite word ... [more ▼]

We introduce a generalization of Pascal triangle based on binomial coefficients of finite words. These coefficients count the number of times a word appears as a subsequence of another finite word. Similarly to the Sierpinski gasket that can be built as the limit set, for the Hausdorff distance, of a convergent sequence of normalized compact blocks extracted from Pascal triangle modulo 2, we describe and study the first properties of the subset of [0, 1]×[0, 1] associated with this extended Pascal triangle modulo a prime p. We consider a sequence (S(n))n≥0 counting the number of positive entries on each row of the generalized Pascal triangle. By introducing a convenient tree structure, we provide a recurrence relation for (S(n))n≥0, we prove that the sequence is 2-regular, give a linear representation and make the connection with the sequence of denominators occurring in the Farey tree. [less ▲]

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See detailVoyage d'étude curriculum et évaluation de la qualité
Pirard, Florence ULg; Goossens, Xavier

Conference (2016, March 25)

Quand ils sont inscrits dans des dispositifs d’accompagnement organisé en réseau et ancré dans les pratiques professionnelles, on peut faire l’hypothèse que les voyages d’étude contribuent à une ... [more ▼]

Quand ils sont inscrits dans des dispositifs d’accompagnement organisé en réseau et ancré dans les pratiques professionnelles, on peut faire l’hypothèse que les voyages d’étude contribuent à une transformation à la fois des acteurs qui découvrent d’autres manières de penser et d’agir et des actions qu’ils sont susceptibles d’améliorer. Ils s’inscrivent dans des dispositifs qui relèvent d’une culture de la professionnalisation. Nous analyserons un dispositif d’accompagnement centré sur le travail avec les familles qui intègre des voyages d’étude pour des professionnel-le-s de l’accueil en collectivité (fonction d’accueil, direction et coordination). Elle questionne la place du voyage d’étude dans le dispositif, les conditions de sa mise en œuvre et les effets observés sur les pratiques professionnelles. [less ▲]

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See detailrapport de mission colloque Rencontres Waterloo Paris 24-25 mars 2016
Raxhon, Philippe ULg

Poster (2016, March 24)

Présence mémorielle de la bataille de Waterloo au cours de la Première Guerre mondiale, dans le contexte du centenaire de l'événement en 1915.

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See detailAnalyse qualitative et quantitative des populations de norovirus murins générées lors d’infections in vitro synchrones et asynchrones avec des souches homologues : détection de phénomènes de dominance, d’interférence due aux particules non-infectieuses et d’exclusion à la surinfection
Di Felice, Elisabetta; Ludwig, Louisa ULg; Toffoli, Barbara et al

Poster (2016, March 24)

RÉSUMÉ Buts du travail La recombinaison est un des mécanismes moteurs de l’évolution génétique des norovirus. Malgré une détection fréquente de séquences recombinantes à partir d’échantillons de terrain ... [more ▼]

RÉSUMÉ Buts du travail La recombinaison est un des mécanismes moteurs de l’évolution génétique des norovirus. Malgré une détection fréquente de séquences recombinantes à partir d’échantillons de terrain, la reproduction du phénomène de recombinaison en conditions de laboratoire semble difficile. Utilisant le modèle du norovirus murin, cette étude a pour objectif d’évaluer de manière qualitative et quantitative les populations virales, y compris potentiellement recombinantes, générées lors de variations des conditions de temps et de multiplicité d’infection dans des expériences de coinfections ou de surinfections in vitro. Méthodes Des cellules RAW264.7 ont été inoculées par deux souches homologues de norovirus murins (infection primaire : Wu20 ; surinfection : CW1) en utilisant des multiplicités d’infection (MOI : Wu20 = 1; CW1= 0.1, 1 ou 10) et des temps d’inoculation (surinfection après un délai allant de 0 minutes à 24 heures) variables. Les surnageants ont été prélevés 24h post-surinfection et une quantification moléculaire discriminante sur la région 5’ du génome a été réalisée. Des cellules ont été ré-inoculées par ces surnageants et 36 isolats ont été amplifiés. Ces isolats ont été caractérisés moléculairement comme de type CW1, Wu20 ou recombinant par une méthode discriminante sur leurs extrémités génomiques 3’ et 5’. Les recombinants potentiels ont été séquencés sur la région génomique classiquement impliquée dans la recombinaison (chevauchement ORF 1/2). Résultats et discussion L’analyse des ratios des isolats a montré une tendance à une dominance potentielle de Wu20 sur CW1 pour les conditions de MOI relatives 0.1/1 et 1/1 avec un phénomène d’exclusion à la surinfection entre les temps t4 (4h post-infection primaire) et t8. Cependant, cette tendance n’a pas été détectée dans la condition de MOI relative 10/1. Ceci suggère une hypothèse de présence de particules défectives interférentes (PDI) dans la population de Wu20 qui pourrait interférer avec les étapes précoces de l’attachement et de l’entrée et donc modifier les ratios attendus 24h post-infection. La comparaison des ratios de copies génomiques a soutenu l’hypothèse de présence de PDI dans la population de Wu20 avec des ratios différents de ceux logiquement escomptés aux MOI relatives 0.1/1 et 1/1, et qui se sont vérifiés cette fois en condition 10/1 (condition dans laquelle CW1 peut retrouver une chance réelle dans la compétition à l’attachement et à la pénétration). Cependant le temps t1 de cette condition a dévié clairement de la tendance générale et pourrait constituer une population virale de choix pour la présence de recombinants ou suggérer un autre mécanisme par lequel CW1 pourrait momentanément être dominant par rapport à Wu20. L’exclusion à la surinfection a également pu être corroborée par l’analyse moléculaire quantitative. Trois isolats ont été détectés comme des recombinants potentiels mais les séquençages n’ont pu les confirmer. Les évènements de recombinaison pourraient avoir eu lieu sur une autre région que celle classiquement décrite. Cette étude permet de montrer que la composition de la population virale peut avoir un effet majeur sur la compétition entre deux norovirus. Elle suggère également l’existence d’un mécanisme d’exclusion à la surinfection. Elle confirme enfin que malgré les fréquentes détections de souches recombinantes in silico, le phénomène de recombinaison est difficile à reproduire in vitro chez les norovirus. [less ▲]

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See detailWavelet-based Methods to Study the Regularity of a Signal: from Theory to Practice
Kleyntssens, Thomas ULg; Nicolay, Samuel ULg

Conference (2016, March 23)

In this talk, I use the notion of wavelet to design multifractal formalisms. I present the theoritical results obtained on the generalized Snu spaces and I show the utility of these generalization ... [more ▼]

In this talk, I use the notion of wavelet to design multifractal formalisms. I present the theoritical results obtained on the generalized Snu spaces and I show the utility of these generalization. Besides, I also apply these formalisms on a practical example: the Mars topography. [less ▲]

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See detailRefractory ceramic molds fabrication by additive methods for low and high melting point metal alloys casting
Bister, Geoffroy; Deschuyteneer, Dorian; Hautcoeur, Dominique et al

Conference (2016, March 23)

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See detailEtude de dermatophytes isolés dans les services de revalidation et physiothérapie d’une structure hospitalière en région Liégeoise (Belgique)
SACHELI, Rosalie ULg; Utri, Tania ULg; Abdel-Sadick, Hidjab Abdoulaye ULg et al

Poster (2016, March 23)

Objectifs : Les dermatophytes sont responsables d’infections de la peau, des ongles et du cuir chevelu. Les espèces anthropophiles peuvent se transmettre d’une personne à une autre par un simple contact ... [more ▼]

Objectifs : Les dermatophytes sont responsables d’infections de la peau, des ongles et du cuir chevelu. Les espèces anthropophiles peuvent se transmettre d’une personne à une autre par un simple contact. Leur présence en milieu sportif (salles de sport, piscine, tatamis), douches collectives, vestiaires des écoles, a été largement décrite. Par contre il existe peu de littérature concernant les établissements de soins. C’est pourquoi, nous nous sommes intéressés au risque potentiel d’infection par des dermatophytes en milieu hospitalier et particulièrement dans les salles de kinésithérapie et de revalidation ainsi que dans une piscine du CHU de Liège. Matériel et méthodes : Trois sites du CHU de Liège ont été investigués: le site du Sart Tilman (ST), le site Ourthe Amblève (OA) et le site Notre-Dame des Bruyères (NDB). Les prélèvements ont été effectués en salle de revalidation et kinésithérapie ainsi qu’à la piscine de revalidation. Ces prélèvements ont été réalisés sur les surfaces à l’aide de géloses de contact (milieu de Sabouraud/chloramphénicol/actidione/gentamicine, Tritium Microbiologie, Pays-bas). L’identification des espèces fongiques a été réalisée par observation macro-microscopique des cultures, spectrométrie de masse (Maldi-Tof) et séquençage moléculaire. Résultats : Au total, 552 prélèvements ont été réalisés parmi lesquels 15 dermatophytes ont été recensés (2,72%). On retrouve: 7 T. rubrum, 7 T. interdigitale, 1 T. mentagrophytes var. mentagrophytes. Sur le site ST, 207 prélèvements ont été effectués parmi lesquels 4 T. rubrum, 1 T. interdigitale et 1 T. mentagrophytes var. mentagrophytes (zoophile). Sur le site OA, parmi les 226 prélèvements effectués, 4 Trichophyton interdigitale et 3 Trichophyton rubrum ont été retrouvés. Aucun dermatophyte n’a été isolé de l’eau de piscine ou pédiluve. Sur le site de NDB, sur 119 prélèvements, seuls 2 isolats de Trichophyton interdigitale ont été identifiés. Les prélèvements positifs pour les dermatophytes concernent des tapis de gymnastique, vélos, rameurs, balances, trampolines, demi-sphères d’équilibre, table de kinésithérapie, sols de douches et vestiaires de la piscine. Conclusion Grâce à ces investigations, nous avons pu mettre en évidence sur le matériel de revalidation et les sols des vestiaires, la présence de deux espèces anthropophiles, T. rubrum et T. interdigitale fréquemment impliquées dans les cas d’onychomycoses et atteintes cutanées. Une souche zoophile de T. mentagrophytes a également été mise en évidence. Cette étude démontre qu’un renforcement de la fréquence de nettoyage des sols et des instruments utilisés dans les salles de sport du CHU de Liège est nécessaire de façon à minimaliser les risques de contamination de patients et du personnel médical. [less ▲]

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See detailCalendars and rituals at Mari during the šakkanakkū period (end of the 3rd millennium B.C. – beginning of the 2nd)
Colonna d'Istria, Laurent ULg

Conference (2016, March 23)

The order of the months in the calendar at the end of the šakkanakkū period (19th century B.C.) is now well established. This calendar is largely similar to the one in use during the amorite period. This ... [more ▼]

The order of the months in the calendar at the end of the šakkanakkū period (19th century B.C.) is now well established. This calendar is largely similar to the one in use during the amorite period. This paper will focus on the rituals and festivals at Mari during the end of the šakkanakkū period: expenditures for temples, deities and rituals are mentioned in many administrative texts dated to the mid-19th century. Nevertheless, these texts are very patchy and the festivals are not clearly named. The latest excavation archaeological excavations at the site of Tell Hariri-Mari provided us with eleven administrative texts dated to the middle of the šakkanakkū period (i.e. UrIII period or slightly earlier). These texts reveal a calendar which is partly similar to the late šakkanakkū one. [less ▲]

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See detailGeophysical Investigation of the Pb-Zn deposit of Lontzen, Belgium
Evrard, Maxime ULg

Conference (2016, March 22)

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See detailOsteopontin predicts radiotherapy response of glioblastoma patients : new role in DNA damage repair
Henry, Aurélie ULg; Nokin, Marie-Julie; Leroi, Natacha ULg et al

Conference (2016, March 22)

- Introduction: Glioblastoma (GBM) is the most aggressive and common solid human brain tumor. Because of GBM heterogeneity, location and aggressiveness, none of the available treatment is curative. These ... [more ▼]

- Introduction: Glioblastoma (GBM) is the most aggressive and common solid human brain tumor. Because of GBM heterogeneity, location and aggressiveness, none of the available treatment is curative. These treatments include maximal surgical resection, radiotherapy and concomitant or adjuvant chemotherapy with Temozolomide. However, the prognosis of adult patients with GBM remains poor and the survival outcome after treatment does not exceed 15 months. GBM-composing cells have developed many strategies to counteract these current therapies. Among the wide hallmarks acquired to survive, high osteopontin (OPN) expression correlates with lower overall and disease-free/relapse-free survival in all tumors combined, as well in brain cancer. Our recent study (Lamour V and Henry A, IJC 2015) has demonstrated the role of OPN in the tumorigenicity of glioblastoma cells and its importance in the maintenance of the stem characters. In the continuation of this work, our recent studies focused on the potential role of OPN in the resistance of GBM cells to radiotherapy and its potential implication in the initiation of Double Strand Breaks (DSBs) repair mechanisms. - Aims: In the context of this study, different GBM cell lines (U251-MG, U87-MG and U87 Viii) were used to assess the role of OPN in the initiation of the DSBs repair mechanism after an exposure to gamma-irradiation. - Methods and results: We performed the transient transfection of different GBM cell lines (U251-MG, U87-MG and U87-MG overexpressing EGFR VIII) with siRNAs specifically directed against OPN. After irradiation, all these OPN-depleted cells consistently showed a lower induction of γ–H2AX compared to control (irrelevant siRNA) as evidenced by western blot and immunofluorescence techniques. Thereafter, clonogenic assays allowed to prove that the survival of OPN-depleted cells was affected after an exposure to irradiation. To assess the importance of OPN expression in the response to radiotherapy, an heterotopic xenograft model was used. In brief, IPTG-inducible U87 shOPN clones were injected subcutaneously in NOD-SCID mice and were allowed to form a tumor. When average tumor volume reached a predetermined size range, mice were treated (or not) with IPTG by intraperitoneal injection during five days. At the end of the treatment, tumors were selectively exposed to gamma-irradiation by using a small animal irradiator X-RAD 225Cx (Precision X-Ray Inc., North Branford, CT). One week later, mice were sacrificed and tumors were measured. In this pilot study, we observed that mice in which the tumor was depleted in OPN displayed a slight regression in the tumor growth compared to mice that received radiotherapy alone (no IPTG), where the tumor volume remained constant. - Conclusions: Taken together, these preliminary data meet the fact that OPN is important in the response of GBM to radiotherapy. The in vitro results converge to the fact that OPN might be implicated in the initiation of the DSBs repair following irradiation. Currently, we would like to investigate this hypothesis in vivo but also to check the effect of OPN depletion combined to radiotherapy on the survival of mice in an orthotopic xenograft model. [less ▲]

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See detailUne généralisation du triangle de Pascal
Stipulanti, Manon ULg

Conference (2016, March 22)

We introduce a generalization of Pascal triangle based on binomial coefficients of finite words. These coefficients count the number of times a word appears as a subsequence of another finite word ... [more ▼]

We introduce a generalization of Pascal triangle based on binomial coefficients of finite words. These coefficients count the number of times a word appears as a subsequence of another finite word. Similarly to the Sierpinski gasket that can be built as the limit set, for the Hausdorff distance, of a convergent sequence of normalized compact blocks extracted from Pascal triangle modulo 2, we describe and study the first properties of the subset of [0, 1]×[0, 1] associated with this extended Pascal triangle modulo a prime p. [less ▲]

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See detailFeasibility study of repetitive diffusion MRI after Neoadjuvant radiotherapy for following tumor microenvironment.
LALLEMAND, François ULg; Leroi, Natacha ULg; Bahri, Mohamed Ali ULg et al

Conference (2016, March 22)

Purpose/Objective. Neoadjuvant radiotherapy (NeoRT) improves tumor local control and tumor resection in many cancers. The timing between the end of the NeoRT and surgery is mostly driven by the occurrence ... [more ▼]

Purpose/Objective. Neoadjuvant radiotherapy (NeoRT) improves tumor local control and tumor resection in many cancers. The timing between the end of the NeoRT and surgery is mostly driven by the occurrence of side effects or the tumor downsizing. We previously demonstrated in an in vivo model that the timing of surgery and the schedule of NeoRT influenced the tumor dissemination. Here, our aim is to evaluate with functional MRI (fMRI) the impact of the radiation treatment on the tumor microenvironment and subsequently to identify non-invasive markers helping to determine the best timing to perform surgery for avoiding tumor spreading. First, we needed to demonstrate the feasibility of repetitive MRI imaging after NeoRT in mice. Material/methods. We used two models of NeoRT we previously developed in mice: MDA-MB 231 and 4T1 cells implanted in the flank of mice. When tumors reached the planned volume, they are irradiated with 2x5 Gy and then surgically removed at different time points after RT. In the mean time between the end of RT and the surgical procedure, mice were imaged in a 9,4T Agilent® MRI. Diffusion Weighted (DW) -MRI was performed every 2 days between RT and surgery. For each tumors we acquired 8 slices of 1 mm thickness and 0.5 mm gap with an “in plane voxel resolution” of 0.5 mm. For DW-MRI, we performed FSEMS (Fast Spin Echo MultiSlice) sequences, with 9 different B-values (from 40 to 1000) and B0, in the 3 main directions. We also performed IVIM (IntraVoxel Incoherent Motion) analysis, in the aim to obtain information on intravascular diffusion, related to perfusion (F: perfusion factor) and subsequently tumor vessels perfusion. Results. As preliminary results, with the MBA-MB 231 we observed a significant increase of F at day 6 after irradiation than a decrease and stabilization until surgery. No other modifications of the MRI signal, ADC, D or D* were observed. We observed similar results with 4T1 cells, F increased at day 3 than returned to initial signal. The difference in the timing of the peak of F can be related to the difference in tumor growth between MBA-MB 231 and 4T1 (four weeks vs one week). Conclusion. For the first time, we demonstrate the feasibility of repetitive fMRI imaging in mice models after NeoRT. With these models, we show a significant peak of the perfusion factor (F) at day 6 or day 3. This change occurs between the two previous time points of surgery demonstrating a difference in the metastatic spreading. Indeed, after a NeoRT of 2X5Gy we observed more metastases in the lung when MDA-MB 231 tumor bearing mice are operated 4 days after RT compared to 11 days. These preliminary results are very promising for identifying noninvasive markers for determining the best timing for surgery. [less ▲]

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See detailEnhanced biomass production of a novel Acetobacter strain isolated from Moroccan biotopes using response surface methodology approach
Mounir, Majid ULg; Hamas, Khadija; Tamraoui, Khadija et al

Conference (2016, March 21)

The objective of this work was first the isolation of novel acetic acid bacteria strains from natural Moroccan habitats, and then, the evaluation of their ability to produce microbial starters for vinegar ... [more ▼]

The objective of this work was first the isolation of novel acetic acid bacteria strains from natural Moroccan habitats, and then, the evaluation of their ability to produce microbial starters for vinegar production in large-scale. The isolation was made from figs, dates, cactus, and traditional fruit vinegars. Four strains, selected from a total of 63 isolates were confirmed to be belonged to Acetobacter species according to biochemical tests and molecular study based on 16s rDNA sequence analysis. Acetic acid fermentation tests, performed on date and apple fermented juices by the selected Acetobacter strains, showed high capacity of acidification. The most efficient strain, isolated from cactus vinegar, yielded an acidity of about 42.5 g/L on apple juice. A cell growth optimization was carried out on the most efficient strain using the response surface methodology (RSM). The linear, quadratic and interaction effects of four factors; ethanol, acetic acid, glucose and pH were studied by the application of a central composite design. 30 experiments were designed to predict the maximum concentration of cell biomass. The optimal calculated values of ethanol, acetic acid, glucose and pH allowing the prediction of the maximum biomass production (2.2 g/L) were 28.18 g/L, 10.12 g/L, 15.15 g/L and 5.33, respectively. Subsequently, further batch fermentations were carried out in a 6 L lab-bioreactor using the optimased culture medium. The results were in line with the predict values. It was concluded that the studied strain is well suited to be used as parental strain to prepare a starter for vinegar fruit production. [less ▲]

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See detail“Rhythm and Repetition in Caryl Phillips’s Dancing in the Dark”
Mascoli, Giulia ULg

Conference (2016, March 20)

My proposal is to deal with Dancing in the Dark (London: Vintage, 2005), a novel by Caryl Phillips, a contemporary British author of Caribbean descent. This narrative is devoted to the Caribbean American ... [more ▼]

My proposal is to deal with Dancing in the Dark (London: Vintage, 2005), a novel by Caryl Phillips, a contemporary British author of Caribbean descent. This narrative is devoted to the Caribbean American entertainer Bert Williams (1874–1922) who was the first black performer in the Ziegfield Follies and it traces his frustrating life as a black performer who had to blackface. Like most of Phillips’s literary production, Dancing in the Dark is shaped by music, both thematically –there are scenes involving musical performances, lyrics interspersed throughout the novel– and formally through the recurrent and creative use of repetitions and meaningful variations in rhythm, and sonic effects. Indeed, various elements of sound are present through poetic language and forms to emphasize elements of rhythm: repetitive devices such as rhymes, meters and alliterations. My contention is that these rhythmic devices partake in the emotional impact of Phillips’s writing; sonic elements emphasize the musical properties of language, strike the reader and prevent them from forgetting the traumatic experience of Bert. Through repetition, they transfer the character’s traumatic experience into the writing and create a sense of sympathy with the reader which privileges immediate empathy. If Bert Williams has been largely forgotten until recently, I believe that Phillips’s rhythmic prose will enable Bert’s story to resonate in the reader’s mind long after closing the book. [less ▲]

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See detailLes PCSK9 : la mort des statines ?
RADERMECKER, Régis ULg

Conference (2016, March 19)

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See detailLes pays émergents : vecteur de sécurité alimentaire en Afrique ? le cas du Brésil au Mozambique
WCusson, Gabrielle ULg

Conference (2016, March 19)

Cette communication a pour objectif d’analyser le rôle des pays émergents dans la coopération agricole en Afrique pour assurer la sécurité alimentaire et énergétique du continent, et plus particulièrement ... [more ▼]

Cette communication a pour objectif d’analyser le rôle des pays émergents dans la coopération agricole en Afrique pour assurer la sécurité alimentaire et énergétique du continent, et plus particulièrement celui du Brésil au Mozambique. Parmi les pays émergents, la Chine, l’Inde et le Brésil s’affichent dorénavant comme des puissances agricoles à l’échelle internationale et détiennent une expertise particulière qu’ils souhaitent partager avec l’Afrique afin de soutenir sa révolution agraire et son insertion au marché mondial. Cependant, cette coopération Sud-Sud (CSS) ne semble pas exempte de bénéfices politiques et commerciaux à l’égard des pays donateurs. Ainsi, les pays émergents proposent-ils un modèle de coopération et de développement différent et solidaire ou reproduisent-ils la structure d’aide traditionnelle Nord-Sud soutenue par les institutions financières internationales? Quels sont les intérêts des puissances émergentes à participer à la nouvelle révolution verte en Afrique ? Plus précisément, cette analyse portera sur la stratégie de CSS du Brésil au Mozambique via le projet ProSAVANA, un projet de coopération triangulaire développé avec le Japon qui vise le transfert du savoir-faire technique et technologique agraire du Brésil dans les savanes africaines à des fins de production de biocarburants; un enjeu clé pour le Brésil. Pour répondre à la question de recherche, nous confronterons le discours officiel du Brésil en terme de CSS avec la réalité qui se dessine au Mozambique. Pour ce faire, nous nous appuierons sur les théories critiques de la nouvelle économie politique. [less ▲]

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See detailClinical and molecular classification of glioblastoma patients
Lambert, Jérémy ULg; Kaoma, Tony; Van Dyck, Eric et al

Poster (2016, March 19)

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See detailGoro Gheri as the "perfect secretary"?
Miesse, Hélène ULg

Conference (2016, March 19)

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See detailThe Islamic coinage of Barqa from the conquest up to the advent of the Fatimids
Bauden, Frédéric ULg

Conference (2016, March 19)

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See detailThérapeutiques conservatrices des tendinopathies : quoi de neuf ?
Kaux, Jean-François ULg

in 11ème Congrès d'actualités diagnostiques, éthiques et thérapeutiques de l'arrondissement de Dinant (2016, March 19)

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See detailWill Big Data Deliver Its Promised Productivity Growth?
Artige, Lionel ULg

Conference (2016, March 18)

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See detailÉcrire (malgré) l'espace aéré. Yves Berger et Edward Abbey au seuil du parc national américain
Di Gregorio, Luca ULg

Conference (2016, March 18)

Edward Abbey et Yves Berger ont nourri l’essentiel de leurs œuvres de leur fascination commune pour l’Ouest américain : plus spécifiquement pour la région du Grand Bassin et le pays des canyons – pays de ... [more ▼]

Edward Abbey et Yves Berger ont nourri l’essentiel de leurs œuvres de leur fascination commune pour l’Ouest américain : plus spécifiquement pour la région du Grand Bassin et le pays des canyons – pays de sable et de grès, pays minéral, sidéral, qui concentre plusieurs des plus fameux parcs naturels des États-Unis. Mais si leur passion s’attache au même objet d’élection – les paysages sublimes du Sud-Ouest –, l’un et l’autre divergent par les voies qu’ils empruntent et les points de vue d’où ils se postent pour le goûter, et surtout pour en rendre compte par l’écriture. En effet, un Océan entier sépare leurs positions vis-à-vis de la nature américaine – mais pas uniquement : chacun représente aussi, pour son pays respectif, une bonne part de l’ethos et de l’habitus qui y valorise d’ordinaire l’écrivain. Ancien ranger saisonnier, Abbey est un écrivain activiste et baroudeur, s’affichant en prise directe avec le terrain, tandis que Berger, protagoniste influent du milieu littéraro-éditorial parisien, rêve d’Amérique en même temps qu’il siège parmi les jurés du Goncourt. En première analyse donc, rien, hormis une vague parenté de génération et un goût du Nouveau Monde, ne justifierait l’association de deux écrivains aussi éloignés l’un de l’autre. Mais nonobstant ce gouffre sociogéographique, ce qui, en dernière analyse, rapproche nos deux auteurs, réside dans l’obstacle commun qui perturbe leur abord de l’Amérique sauvage: le National Park Service et son immense réseau d’espaces aérés naturels, quadrillant, pour les protéger (et les promouvoir), les plus fameux paysages de l’Ouest. Là où Abbey rejoint Berger, et réciproquement, c’est dans cette façon de mal assumer l’importun isolant phénoménologique qu’est le parc, d’éprouver une nette complication à écrire et ressentir la Nature au travers de son interférence. Phénomène non-naturel par excellence, ce seuil que pose le parcage leur pose, à eux, un lourd problème, puisqu’il leur renvoie la part d’impossible du rapport qu’ils désirent cultiver avec le Grand Ouest. Là encore cependant, même cet « impossible » se manifeste différemment à chacun. Comment, pour le ranger Abbey, évoquer une intimité native avec le cosmos en dépit du cadenassage institutionnel dont il est partie prenante? Comment, pour le Français Berger, passer dignement en Amérique à la façon d’un vrai voyageur, en évitant de rendre l’effet d’un touriste anonyme, téléguidé par le balisage et la signalétique du parc naturel ? Heurtant le désir d’immanence à la wilderness de l’un, le parc compromet aussi l’aspiration au voyage authentique de l’autre : tel est le « problème » du parc, dont on analysera ici quelques symptômes et solutions poétiques au sein de deux œuvres ayant pour cadre la région des Four Corners1 : l’incontournable Desert Solitaire (1968) d’Abbey, véritable bible du Nature Writing en Amérique, dialoguera ainsi avec La Pierre et le Saguaro (Prix de la langue française, 1990) d’Yves Berger. Mais préalablement, et alors que le National Park Service fête cette année son centenaire, il convient de faire un rapide point théorique et phénoménologique sur ce qu’implique et recouvre l’objet culturel « parc américain ». [less ▲]

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See detailLes libéraux belges et le national-socialisme (1933-1945)
Brüll, Christoph ULg

Conference (2016, March 18)

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See detailMarker et mémoire
Pieron, Julien ULg

Conference (2016, March 18)

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See detailRecollection versus familiarity in normal aging and in mild cognitive impairment: Impact of test format
Gilsoul, Jessica ULg; Simon, Jessica ULg; SALMON, Eric ULg et al

Poster (2016, March 18)

Objectives. Memory retrieval typically involves a combination of recollection and familiarity. However, test format can promote one or the other process (Norman & O’Reilly, 2003). The aim of this study ... [more ▼]

Objectives. Memory retrieval typically involves a combination of recollection and familiarity. However, test format can promote one or the other process (Norman & O’Reilly, 2003). The aim of this study was to investigate the impact of test format on recollection and familiarity in normal aging and in mild cognitive impairment (MCI). Methods. Seventy young participants (18-30 years), 65 “younger-old” (55- 69 years), 53 “older-old” (70-85 years), and 13 MCIs (55-82 years) were enrolled. In the “forced-choice” task, they had to recognize which picture, among three, was presented during the encoding stage. In the “yes/no” task, they had to judge whether each item, successively presented, was previously seen or not. In each task, they had to give a “Remember/Know/Guess” judgment. Results. Group × Format repeated measures ANOVAs revealed that young people had better recognition performance (d’) than “younger-old”, which were better than “older-old” and MCIs. Moreover, young people used familiarity more accurately than both groups of old participants and MCIs, with MCIs being equivalent to “younger-old” and “older-old”. However, MCIs displayed a high rate of familiarity-based false alarms. The resort to recollection decreased with age and in MCIs. Finally, Group × Format interaction revealed that young people (but not the other groups) could use recollection more often in the “forcedchoice” task compared to the “yes/no” task. Conclusions. Recollection and familiarity decline progressively in healthy aging. In MCI, recollection is more affected than familiarity, but patients demonstrated a more liberal use of familiarity. Finally, test format did not influence strongly the results. [less ▲]

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See detailRegain of fitness through in vitro replication for a recombinant murine norovirus
de Oliveira-Filho, Edmilson; Ludwig, Louisa ULg; Toffoli, Barbara et al

Poster (2016, March 18)

INTRODUCTION Molecular mechanisms driving norovirus evolution are the accumulation of point mutations and recombination. Recombination can create considerable changes in viruses, allowing for complete ... [more ▼]

INTRODUCTION Molecular mechanisms driving norovirus evolution are the accumulation of point mutations and recombination. Recombination can create considerable changes in viruses, allowing for complete antigenic shifts, host jumps and fitness and pathogenesis modifications. Mathijs et al. recently isolated a viable recombinant murine norovirus (RecMNV) in vitro after coinfection of two parental MNV strains (MNV1-CW1 and -WU20) in a mouse leukaemic monocyte-macrophage cell line (RAW 264.7). The ensuing RecMNV possessed reduced in vitro fitness compared to its parental strains but has also been shown to have retained in vivo infectivity (Mathijs et al, submitted). The aim of this study was to follow the replicative and genetic adaptations of RecMNV over serial in vitro passages in order to characterise its capability of replicative fitness adaptation. MATERIALS AND METHODS: RecMNV was serially replicated in vitro in monolayers of RAW 264.7 cells over ten passages. Following a first initial infection at an MOI of 0.05, cell layers were consecutively infected with 100 μl neat supernatant of the preceding passage. Two independent lysis plaque assays were performed in triplicate with RecMNV progenies resulting from the first (early) and tenth (late) passage (RecE and RecL). Viral plaque sizes of RecE and RecL were measured with image processing program Image J and statistical analyses of plaque size diameters were subsequently performed. To obtain the complete genome sequences of RecE and RecL, a sequencing strategy was developed in which the MNV genome was divided into seven regions and amplification was performed using overlapping primers. Nucleotide sequences of RecE and RecL were analysed via BioEdit Sequence Editor. Growth curves of RecE and RecL progenies were established for high (10) or low MOI (0.01). RESULTS After ten in vitro passages, viral lysis plaque size diameters had increased significantly. Molecular analysis of RecMNV and both parental strains showed nine nucleotide mutations in the RecMNV genome, comprising three non-silent mutations. In addition, a mutation at position 7245 (A187G) introduced a stop codon, resulting in a 20 AA shorter VP2 in RecMNV (for both RecE and RecL). A comparison of RecE and RecL revealed four non-silent mutations in the NS1-2 and NS7 region of ORF1, two of which were present in the latter region (G1384D and S1393N). DISCUSSION This is the first study in which the fitness of a recombinant NoV strain was evaluated in vitro. Our data provides evidence of viral adaptation to a new environment (here a cell culture system) after a recombination event. Evidence of gain-of-function of RecMNV was demonstrated by differences in growth curves and viral lysis plaque size. In addition, non-silent mutations associated to the gain-of-function/in vitro adaptation were detected. It is noteworthy, that the mutation causing a shorter VP2 in RecE and RecL did not compromise its ability to infect and replicate either in vitro or in vivo (Mathijs et al, submitted). As a perspective we should like to characterise the precise mutation(s) responsible for the fitness regain via infectious clone assay. [less ▲]

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See detailPrecision of novel bio-based and ethylene-based copolymers: application to advanced nanocomposites
Scholten, Philip ULg; Detrembleur, Christophe ULg; Meier, Michaël et al

Conference (2016, March 18)

Polyolefins are an inexpensive class of compounds that can be used to prepare a plethora of different materials. Poly(ethylene) is the worldwide most produced polymer and is mostly synthesised by free ... [more ▼]

Polyolefins are an inexpensive class of compounds that can be used to prepare a plethora of different materials. Poly(ethylene) is the worldwide most produced polymer and is mostly synthesised by free radical polymerisation or catalytic coordination insertion using high temperature and pressure. The controlled radical polymerisation of ethylene is very difficult to achieve because of secondary reactions of this unconjugated monomer, e.g. chain transfer and termination reactions. Cobalt-mediated radical polymerisation (CMRP) represents a solution to control its polymerisation in mild conditions: in a reversible deactivation mechanism, a cobalt complex reversibly traps the active growing chains and converts them into dormant species, avoiding side reactions and allowing for a controlled polymerisation. Using CMRP, statistical copolymers of ethylene and vinyl acetate (VAc) have been synthesised, as well as block-like and block copolymers. Furthermore, functionalisation of the α- and ω-chain ends are now possible. Incorporating other monomers, e.g. vinyl esters or vinyl amides, into an ethylene copolymer by CMRP will lead to completely new and highly interesting materials which may act as compatibilisers for the dispersion of natural polymers, such as cellulose, into various polymer matrices. The goal of this work is to design novel well-defined functional polyethylenes that are expected to improve the dispersion of natural polymers into polyolefins. [less ▲]

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See detailPancreatic Beta Cell Regeneration: Duct Cells Act as Progenitors in Adult Zebrafish
Bergemann, David ULg; Ghaye, Aurélie; Tarifeño, Estefania et al

Poster (2016, March 18)

Diabetes is characterized by the loss of insulin producing beta cells. Although different therapeutic strategies do exist, they lack precise and dynamic control of glycemia as carried out by endogenous ... [more ▼]

Diabetes is characterized by the loss of insulin producing beta cells. Although different therapeutic strategies do exist, they lack precise and dynamic control of glycemia as carried out by endogenous beta cells. One promising alternative is to replenish the pancreas with bona fide functional beta cells by triggering regeneration mechanisms. Previous studies have shown beta cell neogenesis but still remain controversial about their origin as they used different models. However, among the different hypotheses, it is tempting to assume that pancreatic ducts contain progenitor/precursor cells in adults. The latter is supported by the fact that the embryonic duct epithelium gives rise to the endocrine lineage, and that in healthy and diabetic human adults, insulin positive cells could be found next to or in pancreatic ducts. Despite these observations, mammals show very limited regenerative capabilities, making it difficult to investigate those mechanisms. In contrast, zebrafish are extensively used for regeneration studies. The ability of adult zebrafish to regenerate its beta cells and restore normoglycemia after massive beta cell ablation has already been shown. Our work focuses on the understanding of the underlying mechanisms leading to this retained potential. Here we show that adult pancreatic duct cells act as progenitors, giving rise to beta cells, in physiological and induced diabetic condition in vivo. To get insight into this process, we conducted RNA-seq experiments on zebrafish pancreatic duct cells. By this mean we could identify new ductal markers and noticed that adult duct cells also show strong expression of embryonic pancreatic progenitor markers. In our ongoing comparative analyses we are deciphering the key genes and pathways needed to set in motion the regenerative machinery. The differences between zebrafish and mammal duct cells that will thereby be underlined might then be transposed to mammalian model s to restore regenerative processes. [less ▲]

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See detail“Everything was losing definition and outline”: Re-membering Trauma Fiction in Gail Jones’s Sorry
Belleflamme, Valérie-Anne ULg

Conference (2016, March 18)

In an article, Australian novelist and essayist Gail Jones confesses of her novel Sorry that it has “a political-allegorical aspect – as one would expect, claiming such a title” (2008, 79). Published in ... [more ▼]

In an article, Australian novelist and essayist Gail Jones confesses of her novel Sorry that it has “a political-allegorical aspect – as one would expect, claiming such a title” (2008, 79). Published in 2007, that is, one year prior to the formal apology delivered by the Australian government to the Aborigines and Torres Strait Islanders, Sorry engages in a reflection on the ethics of reconciliation. Written in response to Jones’s wish to acknowledge the debt to the Stolen Generations, the novel also offers new possibilities of ethical mourning, allowing the dead to return and the voiceless to speak. My paper will seek to explore the ways in which Jones draws on trauma fiction to bypass not only the unsayable dimension of Australia’s history and what she elsewhere criticises as the trauma model’s “transferential gesture of victim surrogacy” symptomatic of postcolonising settler cultures (2004, 162) but also the representational difficulties inherent in trauma. Moreover, it is by introducing into her novel the concept of traumatic time, “a time that is broken, and […] recursive” (qtd. in Block 2008) and which mirrors on the level of form and structure the effects that trauma exerts on its victims, that Jones she recreates a narrative model that echoes an Australian discourse pre-dating the Bringing Them Home report – that is tinged with amnesia, fragmented memories, and silence –, against which she will assert her own counter-discourse. Works Cited: - Block, Summer. 09 May 2008. “Interview: Gail Jones.” Interview. January Magazine. Web. 16 Jan. 2013. - Jones, Gail. 2004. “Sorry-in-the-Sky: Empathetic Unsettlement, Mourning, and the Stolen Generations.” In Imagining Australia: Literature and Culture in the New New World, edited by Judith Ryan and Chris Wallace-Crabbe, 159-171. Cambridge, MA: Harvard University Press. - Jones, Gail. 2007. Sorry. London: Harvill Secker. - Jones, Gail. 2008. “Speaking Shadows: Justice and the Poetic.” In Just Words?: Australian Authors Writing for Justice, edited by Bernadette Brennan, 76-86. St Lucia: University of Queensland Press. [less ▲]

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See detail“From another angle”: the Australian Reconciliation in Gail Jones’s Sorry and Five Bells
Belleflamme, Valérie-Anne ULg

Conference (2016, March 17)

On 26 May 2000, an estimated 250,000 people – Australian novelist and essayist Gail Jones included – walked across the Sydney Harbour Bridge in support of the Australian Reconciliation process. More ... [more ▼]

On 26 May 2000, an estimated 250,000 people – Australian novelist and essayist Gail Jones included – walked across the Sydney Harbour Bridge in support of the Australian Reconciliation process. More importantly, eight years later, Jones claimed that “in writing [her novel Sorry] [she] rehearsed [her] own concern that the reconciliation process not be forgotten – since it has certainly faded from the political agenda since the bridge walk of 2000[” (2008: 84). This and her claim that “the heartwarming Sorry Books [...] ought seriously to be considered within the genre of the poetics of political dissent, and not as casual or sentimental acts of mere signature” (2008: 164) are indicative of Jones’s writing and of her wish to subvert the stereotypical and ambiguous discursive manifestations of the Australian Reconciliation. By the same token, her novels Sorry (2007) and Five Bells (2011) offer a complex picture of the ethics of reconciliation, namely one that includes “an admission of uncertainty, a calculation of difficulty, and an awareness that justice – and human relations – is rarely written in black and white” (Jones 2008: 86). My paper will thus seek to explore how Jones, by drawing on forms of narrative indirections in both, Sorry and Five Bells, distances herself from white Australian writers who deal with the Stolen Generations in a way that seems to appropriate Aboriginal and Torres Strait Islander peoples’ experiences. Sorry and Five Bells, then, offer an alternative to standard reconciliation practices, with a view to bridging the gap between white Australia’s history and the history of the Aborigines. References: - Jones, Gail. 2008a. Sorry. London: Vintage. - Jones, Gail. 2008b. Speaking shadows: Justice and the poetic. In Just Words?: Australian Authors Writing for Justice, Bernadette Brennan (ed.). St Lucia, Qld.: University of Queensland, 76-86. - Jones, Gail. 2012. Five Bells. London: Vintage. [less ▲]

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See detailEnhancing the salience of perceptual fluency improves familiarity-based recognition memory in aging
Bastin, Christine ULg; Willems, Sylvie ULg

Poster (2016, March 17)

Objective. Normal aging is characterized by decreased recollection, but better preserved familiarity. Memory tasks that facilitate the use of familiarity should allow attenuating age-related differences ... [more ▼]

Objective. Normal aging is characterized by decreased recollection, but better preserved familiarity. Memory tasks that facilitate the use of familiarity should allow attenuating age-related differences in memory. The study tested two hypotheses: (1) can the reliance on familiarity during recognition memory be promoted by increasing the difference in perceptual processing fluency between old and new items; (2) can this manipulation reduce age-related difficulties in episodic memory? Methods. Twenty-four young and 24 older adults performed two verbal recognition memory tasks. In the No-Overlap task, target words and new words did not share any letter. Prior exposition to the target words thus induced increased processing fluency of the words and letters, so that fluency difference was a salient and reliable cue to discriminate between old and new words. In the Overlap task, target and new words had letters in common, so fluency cues were less useful. Recollection and familiarity was assessed with the Remember/Know/Guess paradigm. Results. There was an age effect on recollection but intact familiarity. Moreover, (1) memory performance was better in the No Overlap than the Overlap task, with a greater hit rate and a smaller false alarm rate associated with familiarity. (2) Age-related differences in recognition accuracy (hits – false alarms) were significantly attenuated in the No Overlap task compared to the Overlap task. Conclusion. These findings suggest that minimizing the perceptual similarity between targets and distractors, and thus increasing processing fluency differences, allowed to reduce the effect of age on recognition memory performance by facilitating the use of familiarity. [less ▲]

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See detail"Parcours fléchés. Seuils et traversées dans l'œuvre de Marc-Antoine Mathieu"
Belloi, Livio ULg

Conference (2016, March 17)

Cette communication se propose d'étudier "Sens" (2014), le dernier album du dessinateur français Marc-Antoine Mathieu. Plus spécifiquement, il s'agissait, conformément au thème directeur du Congrès de St ... [more ▼]

Cette communication se propose d'étudier "Sens" (2014), le dernier album du dessinateur français Marc-Antoine Mathieu. Plus spécifiquement, il s'agissait, conformément au thème directeur du Congrès de St. Louis, d'examiner l'œuvre de Mathieu sous l'angle de son dispositif péritextuel (première de couverture, prologue, couverture intérieure). [less ▲]

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See detailLa Province au défi de la Sixième réforme de l'État
Grandjean, Geoffrey ULg

Conference (2016, March 17)

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See detailThe impact of cognitive reserve on recognition memory performance is dependent of the task format in healthy aging
Simon, Jessica ULg; Gilsoul, Jessica ULg; Bastin, Christine ULg

Poster (2016, March 17)

Objective: According to the cognitive reserve hypothesis (Stern, 2009), individuals who have developed a high level of reserve should resist better to the effects of aging than individuals with lower ... [more ▼]

Objective: According to the cognitive reserve hypothesis (Stern, 2009), individuals who have developed a high level of reserve should resist better to the effects of aging than individuals with lower cognitive reserve. In this study, we identified the factors of cognitive reserve that impact most memory performance in aging. Methods: 118 healthy older participants performed one yes/no recognition task and one 3-alternative forced-choice recognition task. For each recognized item, participants provided a Remember/Know/Guess judgment. Furthermore, participants completed a questionnaire assessing different aspects of cognitive reserve (level of education, occupation, physical, social, cultural and intellectual activities). We determined the moderators of cognitive reserve that explain a significant proportion of variance for each memory index through stepwise regression analyzes (p<0.05). Results: In the forced-choice test, the level of education explained positively the use of recollection and negatively the level of false alarms associated with familiarity. In the yes/no recognition task, the precision of recognition was explained positively by the physical activities. Recollection was positively explained by the physical activities and the level of education. Finally, the level of false alarms associated with familiarity was explained negatively by the level of education although the precision of the use of the familiarity is explained positively by physical activities. Conclusion: The more older adults were educated and/or were practicing physical activities, the better their recollection was. The impact of the moderators of the cognitive reserve is dependent on the format of the recognition task. [less ▲]

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See detailComment lire les textes informatifs au début du secondaire?
De Croix, Séverine ULg

Conference (2016, March 17)

Pourquoi et comment apprendre à lire les textes informatifs dans les différentes disciplines au début de l'enseignement secondaire ? Pour tenter de répondre à cette double question, l'auteure s'efforce ... [more ▼]

Pourquoi et comment apprendre à lire les textes informatifs dans les différentes disciplines au début de l'enseignement secondaire ? Pour tenter de répondre à cette double question, l'auteure s'efforce tout d'abord d'identifier les spécificités de ces textes et des modes de lecture qu'ils impliquent. Elle propose ensuite quelques repères, fondés sur différents travaux de recherche récents, quant aux pratiques et dispositifs didactiques qui y sont adaptés. [less ▲]

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See detailThe Bullshit Abstract: From Critique to Reflexive Practice
Van Oudheusden, Michiel ULg; Charlier, Nathan ULg; Claisse, Frédéric ULg

Conference (2016, March 17)

Academics use the abstract to summarize and communicate a research paper’s focus, methods, findings, and conclusions. However, not all abstracts are convincing. Many are bland, uninspired, or outright ... [more ▼]

Academics use the abstract to summarize and communicate a research paper’s focus, methods, findings, and conclusions. However, not all abstracts are convincing. Many are bland, uninspired, or outright stupid, as authors do not always know what they want to say or how to communicate complex research in the space of a few hundred words. They hence often convey the kind of “intelligent stupidity,” which Robert Musil (1937) said could hardly be “distinguished from talent, progress, hope or improvement.” By implication, abstracts are prone to contain and perpetuate “academic bullshit” (Frankfurt 2005), broadly understood as forms of academic expression that meet the stylistic academic standards but generate content that is deceptive, doubtful, or irrelevant. Taking this inherent disposition towards bullshit in the academic abstract as its entry point, this paper presents ten self-authored “bullshit abstracts,” which draw inspiration from various academic fields. Far from denouncing bullshit outright, it acknowledges the inevitable character of bullshit in academic writing (Eubanks and Schaeffer 2008). It urges academics to reflexively consider, and perform, their roles as researchers and writers in view of the challenges they face today, such as reputation management and the pressure in academia to publish or perish; and their complete lack of sensitivity to the odorous aspects of writing. [less ▲]

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See detailEvaluation results of ECHAM-HAMMOZ
Schultz, Martin; Taraborrelli, Domenico; Franco, Bruno ULg et al

Conference (2016, March 16)

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See detailNursing student’s perception of the educational efficiency between two strategies of education: Problem Based Learning and the High-Fidelity Simulation.
Servotte, Jean-Christophe ULg; Guillaume, Michèle ULg

Conference (2016, March 16)

Introduction: The teaching’s evolution in nursing education has to answer the challenge to stimulate the student’s skills development. According to literature review, it’s necessary to compare High ... [more ▼]

Introduction: The teaching’s evolution in nursing education has to answer the challenge to stimulate the student’s skills development. According to literature review, it’s necessary to compare High-Fidelity Simulation (HFS) with other pedagogical methods. Furthermore, the comparison with Problem Based Learning (PBL) was not studied yet. Methods: Two indicators were evaluated : student satisfaction self-confidence. For this, two validated scales were used : Student Satisfaction Learning Scale and Self-Confidence in Learning Using Simulations Scale. 141 nursing’s students were involved in the study. They were exposed to the two pedagogical methods (PBL and HFS). The experience was organized according a complete cross plan. Results: The results demonstrated a higher level of the student’s confidence and the student’s satisfaction in learning for the HFS compare to PBL. Carry-over effects were study. It was concerning the teaching style (questions 3 and 5) as well as the varieties of educational tools (questions 2 and 4). The perception of the value of the PBL during the second period was systematically lower while the score obtained for the HFS for the two periods remains almost identical. Conclusion: A clear superiority of the HFS compared with the PBL is perceived by the students. This result seems to open new opportunities with the HFS method in the education nursing student. Nevertheless, research must be conducted in order to better understand the value of this new pedagogic approach. [less ▲]

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See detailCharacterization of the impact of tillage and nitrogen fertilization on the root development of a winter wheat crop by use of NIR hyperspectral imaging combined to chemometrics
Fraipont, Guillaume ULg; Eylenbosch, Damien ULg; Fernández Pierna, Juan Antonio et al

Poster (2016, March 16)

The objective of this study is to characterize the impact of tillage management and nitrogen fertilization on the root system development of a winter wheat crop. To reach this objective, an innovative ... [more ▼]

The objective of this study is to characterize the impact of tillage management and nitrogen fertilization on the root system development of a winter wheat crop. To reach this objective, an innovative root quantification method that combines NIR hyperspectral imaging (NIR-HSI) and chemometric tools will be applied. [less ▲]

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See detailFoot identification from digital 3D models of lion tracks and paws
Marchal, Antoine ULg; Lejeune, Philippe ULg; De Bruyn, Nico

Conference (2016, March 15)

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See detailGetting on Board but How? Conflicting Perspectives on the Role of the Social Sciences and Humanities in Radiation Protection
Van Oudheusden, Michiel ULg; Rossignol, Nicolas ULg; Perko, Tanja et al

Conference (2016, March 14)

In Europe, science research policy is predicated on the understanding that science and technology (S&T) serve societal needs. Accordingly, European Framework Programs urge scientists and technologists to ... [more ▼]

In Europe, science research policy is predicated on the understanding that science and technology (S&T) serve societal needs. Accordingly, European Framework Programs urge scientists and technologists to give due attention to societal and ethical aspects of S&T, and to engage with social scientists and humanists when doing research and reaching out to society. Starting from these policy prescriptions and from invitations from befriended life scientists to "get on board," we explore the terms of our involvement as social scientists and humanists in a European Joint Program on radiation protection research (EJP-CONCERT). We illuminate recurring tensions between instrumental, normative, and substantive perspectives on the role of the social sciences and humanities (SSH) in radioprotection research and nuclear S&T. Our aim is to shed light on the controversial and contingent nature of integrating SSH into nuclear S&T, as actors articulate divergent assumptions and expectations about SSH and society. These expectations pertain to the value of SSH research for S&T, issues of trust and legitmacy, and different perspectives on risk and uncertainty. By rendering these tensions explicit we seek to probe the implications for SSH of developing a separate SSH Strategic Research Agenda (SRA) within radiation protection research. [less ▲]

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See detailGel Beads to Investigate Sedimentation
Leleu, David ULg; Pfennig, Andreas ULg

Conference (2016, March 14)

Separation of liquid-liquid dispersions with multiple phases involves different interactions between the different dispersed species present in the system, which makes it difficult to predict e.g. the ... [more ▼]

Separation of liquid-liquid dispersions with multiple phases involves different interactions between the different dispersed species present in the system, which makes it difficult to predict e.g. the separation behaviour. Nevertheless such systems are relevant in chemical engineering e.g. for systems involving gas bubbles and simultaneously solid particles like in a fermentation broth. Models for describing the sedimentation behaviour as a basis for settler design are available in principle but have not been systematically validated for variation in size-distribution and e.g. density differences between the various species in the system. Thus, to design technical separation equipment, the separation process has to be better understood, which requires the study of the sedimentation as a first step. This project is focused on the interactions which may occur between each species during the sedimentation e.g. the effect on sedimentation of descending particles when they meet ascending drops. However, a proper study of the sedimentation with fluid phases is difficult due to other phenomena occurring simultaneously, e.g. coalescence. To overcome this issue, the use of gel beads is proposed, which due to their solid interface cannot coalesce. In addition, it is easy to define their parameters which are the density, the hardness and the size distribution. Besides, they can also be preserved during an extended period of time, experiments can thus be reproduced many times with identical beads. During the project, gel beads are designed with different particle size distributions and with different densities. Different batches of the produced gel beads will be mixed to simulate systems with different dispersed phases discriminated via density and different size distributions. With these multiple dispersed phases Experiments will be performed in a settling cell in order to evaluate the overall sedimentation velocity at certain hold up. Simultaneously a new method for measurement of local hold-up profile in the dispersion is tested, which allows hold-up measurement even in opaque systems. Finally sedimentation models found in the literature are compared and adapted to experimental results for predict the sedimentation of systems which involve different dispersed phases. In the presentation the new hold-up measurement will be presented together with an error analysis, experiments on the sedimentation of multiple dispersed phases and the model evaluation will be presented. [less ▲]

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See detailOpening risk gouvernance with a vigilance system: lessons learned from the Blue Tongue Virus outbreak in 2006
Fallon, Catherine ULg

Conference (2016, March 14)

This contribution results from a field research by a multidisciplinary group of veterinary and political scientists and gives an analyses of the transformations of an epidemiosurveillance governance ... [more ▼]

This contribution results from a field research by a multidisciplinary group of veterinary and political scientists and gives an analyses of the transformations of an epidemiosurveillance governance system dedicated to animal diseases, when confronted to new emerging threats in the wake of global changes (Fallon et al., in Vertigo 12(3) 2012) . The research field refers to the emergence of bluetongue virus serotype 8 in 2006 in Belgium and it mobilises the results of a survey based on Delphi method involving relevant public servants and scientists, which showed that most of the means proposed by the authorities are based on the logic of known risk management. However we can identify attempts for renewal and organisational learning, especially with the proposal of a new vigilance system, which allows open discussion and reporting through the decision process. In terms of prevention and anticipation of the adverse event), these changes are intended to accommodate the surveillance system reactivity against uncertain and unforeseen events. We question the problems faced by this transformation and its potential for enriching and reconfiguring the conceptualisation of risk management which is currently dominant in the sector. Finally the article identifies two drivers for change in the governance network : by admitting the persistence of unavoidable cognitive uncertainty and by recognizing the importance for opening up arenas of expert knowledge. [less ▲]

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See detailAgeism and communication in oncology
Schroyen, Sarah ULg; Adam, Stéphane ULg; Marquet, Manon ULg et al

Poster (2016, March 11)

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See detailThe roads of colouring materials: from sources to residues
Pradeau, Jean-Victor; Dayet, Laure; Salomon, Hélène ULg

Conference (2016, March 11)

Economic systems and social relationships gain an increasing complexity in prehistoric periods. Despite their symbolic value and their informative potential in these issues, colouring materials (“ochre” ... [more ▼]

Economic systems and social relationships gain an increasing complexity in prehistoric periods. Despite their symbolic value and their informative potential in these issues, colouring materials (“ochre”, iron oxi(hydrxi)des, cinnabar, etc.) had received scant attention compare to obsidian, flint, metals or igneous rocks. Since the 2000’s, trace elemental analysis (PIXE, XRF, INAA, ICP-MS) and petrographic studies give keys to collect gitological and sourcing data. This methodology has recently improved quantitative knowledge on colouring material’s acquisition modalities and on global technic system itself. Contrasting situations are indeed highlight: archaeological corpus may consist of several raw colouring materials, unequally shared, providing from site range, close diffusion area or far diffusion area. Furthermore, the status of the different geomaterials, the diffusion modalities – direct acquisition, direct or indirect exchanges – and the identity of exporters, transporters and receivers (if any) stay unclear. Two main topics should liven up this session: a fruitful debate on different methodologies depending on geographical contexts and diachronic revue of colouring material procurement through the lens of cultural contexts and site’s status. [less ▲]

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See detailThe Macroeconomics of PAYG Pension Schemes in an Ageing Society
Artige, Lionel ULg

Conference (2016, March 10)

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See detailL'ENMG...c'est le pied
WANG, François-Charles ULg

Conference (2016, March 10)

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See detailTransient neonatal diabetes mellitus due to paternal uniparental disomy of chromosome 6.
FUDVOYE, Julie ULg; Farhat, Khaldoun; Nicolescu, Ramona

Conference (2016, March 10)

Detailed reference viewed: 25 (1 ULg)
See detailIntroduction au séminaire
Francois, Jeromine ULg; Regibeau, Julien ULg

Conference (2016, March 09)

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See detailSpecialization SIAMU : past, present and future
Servotte, Jean-Christophe ULg

Conference (2016, March 08)

Présentation de l'histoire de la spécialisation SIAMU avec un focus sur la simulation.

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See detailMOOCs in business administration - An overview of assessment practice
Gherib, Camelia; Dujardin, Jean-Marie ULg; Verpoorten, Dominique ULg

in Proceedings of the Conference of the European Association for Practitioner Research on Improving Learning (EAPRIL) 2015, Issue 2 (2016, March 07)

The study explores 31 MOOCs in the field of business administration, equipped with a conceptual framework documenting 18 facets of assessment design. As a second step, the data collected on 3 MOOCs about ... [more ▼]

The study explores 31 MOOCs in the field of business administration, equipped with a conceptual framework documenting 18 facets of assessment design. As a second step, the data collected on 3 MOOCs about assessment is submitted to university members in charge of external courses accreditation procedures in order to ascertain its possible influence on their decision to credit a MOOC or not. Main results indicate that, a) the typical profile of the assessment procedure for MOOCs in business administration is: QCM-based, automatic, continuous, individual, product-centred, standardized, b) secure ways (proctoring, test-centres) to warrant learners’ identity for the tests can already be found in some MOOCs of this field, and c) concerns of course accreditors bear first and foremost on these student authentication aspects. [less ▲]

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See detailThe Many AUrorae of Jupiter : Auroral Ffilaments, Flares, Transient features of the main oval, Swirls, Polar dawn spots, Injection signatures and Satellite footprints
Bonfond, Bertrand ULg

Conference (2016, March 07)

The presentation is a review of the many features of the Jovian aurorae in the frame of the imminent arrival of the Juno spacecraft around Jupiter, with a special focus on the most recent results.

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See detailMOOCs in business administration - An overview of assessment practice
Gherib, Camelia; Dujardin, Jean-Marie ULg; Verpoorten, Dominique ULg

in Proceedings of the Conference of the European Association for Practitioner Research on Improving Learning (EAPRIL) 2015, Issue 2 (2016, March 07)

The study explores 31 MOOCs in the field of business administration, equipped with a conceptual framework documenting 18 facets of assessment design. As a second step, the data collected on 3 MOOCs about ... [more ▼]

The study explores 31 MOOCs in the field of business administration, equipped with a conceptual framework documenting 18 facets of assessment design. As a second step, the data collected on 3 MOOCs about assessment is submitted to university members in charge of external courses accreditation procedures in order to ascertain its possible influence on their decision to credit a MOOC or not. Main results indicate that, a) the typical profile of the assessment procedure for MOOCs in business administration is: QCM-based, automatic, continuous, individual, product-centred, standardized, b) secure ways (proctoring, test-centres) to warrant learners’ identity for the tests can already be found in some MOOCs of this field, and c) concerns of course accreditors bear first and foremost on these student authentication aspects. [less ▲]

Detailed reference viewed: 251 (5 ULg)
See detailCardio-pulmonary mechanics and minimal modelling in critical care
de Bournonville, Sébastien; Pironet, Antoine ULg; Desaive, Thomas ULg et al

Poster (2016, March 04)

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See detailCardio-pulmonary mechanics and minimal modelling in critical care
de Bournonville, Sébastien; Pironet, Antoine ULg; Desaive, Thomas ULg et al

in 14th Belgian Day on Biomedical Engineering (2016, March 04)

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See detailPropositions pour penser la notion d'erreur en photographie
Havelange, Carl ULg

Conference (2016, March 04)

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See detailEuthanasie et don d'organes
DETRY, Olivier ULg

Conference (2016, March 04)

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See detailRepeated Behavioral Assessments in Patients with Disorders of Consciousness
Wannez, Sarah ULg; Annen, Jitka ULg; Aubinet, Charlène ULg et al

Conference (2016, March 04)

The Coma Recovery Scale Revised (CRS-R) is considered as the most sensitive scale to assess patients with disorders of consciousness (DOC). Guidelines recommend repeated assessments because patients might ... [more ▼]

The Coma Recovery Scale Revised (CRS-R) is considered as the most sensitive scale to assess patients with disorders of consciousness (DOC). Guidelines recommend repeated assessments because patients might suffer from consciousness fluctuations, but it is not specified how many assessments are needed. The present study included 131 patients with DOC. They have been assessed at least 6 times during a 14-days period with the CRS-R. Results show that 5 CRS-R assessments are needed to reach a reliable diagnosis, and that all the CRS-R subscales are influenced by consciousness fluctuations. We here showed that consciousness fluctuations influence the behavioral diagnosis, and that 5 assessments within a short period of time are needed to get a reliable clinical diagnosis. [less ▲]

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See detailParameter Correlation Analysis in Four Mathematical Models of Left Ventricular Relaxation
Pironet, Antoine ULg; MORIMONT, Philippe ULg; Dauby, Pierre ULg et al

in 14th Belgian Day on Biomedical Engineering (2016, March 04)

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See detailRelative positioning with Galileo E5 AltBOC code measurements
Deprez, Cécile ULg

Conference (2016, March 03)

Depuis une dizaine d’années, l’Europe développe son propre système de positionnement par satellites (ou Global Navigation Satellites System (GNSS) en anglais), connu sous le nom de Galileo. À la pointe de ... [more ▼]

Depuis une dizaine d’années, l’Europe développe son propre système de positionnement par satellites (ou Global Navigation Satellites System (GNSS) en anglais), connu sous le nom de Galileo. À la pointe de la technologie, les horloges atomiques embarquées à bord de ses satellites ainsi que les signaux transmis par ces derniers sont extrêmement prometteurs dans beaucoup de domaines. Bien que toujours en phase de test à l’heure actuelle, ce système a déjà conduit à de premières mesures, notamment en matière de positionnement. Parmi ces nouvelles technologies, un signal en particulier semble très prometteur : Galileo E5, aussi appelé Galileo E5a+b ou encore Galileo E5 AltBOC. Ce signal permet d’effectuer des mesures de code et de phase plus précises. Il est également moins sensible au multi-trajet. Grâce à ses caractéristiques innovantes, Galileo E5 devrait permettre d’estimer des positions avec une précision supérieure à tous les autres signaux utilisés aujourd’hui. Une étude comparative des positions estimées avec les systèmes GPS (américain) et Galileo (européen) sur leurs différentes fréquences émises (GPS L1, GPS L2, GPS L5 pour GPS et Galileo E1, Galileo E5a, Galileo E5b et Galileo E5 AltBOC pour Galileo) a été menée dans ce mémoire. Pour ce faire, une combinaison d’observations appelée double différence (DD) est utilisée sous différentes configurations (ligne de base nulle (ZB), courte (SB) et moyenne (MB)) de récepteurs GNSS. Les récepteurs utilisés appartiennent à l’Université de Liège (2 récepteurs Trimble NetR9, 1 récepteur Septentrio XS et un récepteur Septentrio X4). Il ressort de cette étude que Galileo E5 AltBOC présente les observations les plus précises (en ZB, toutes sources d’erreurs éliminées). L’analyse démontre également qu’une précision de l’ordre de quelques décimètres sur la position à déterminer peut être atteinte avec les codes transmis par le signal Galileo E5, et ce jusqu’à 25 kilomètres de distance. [less ▲]

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See detailSalon de la géomatique F.I.G. 2016 - Saint-Dié
Donnay, Jean-Paul ULg

Conference (2016, March 03)

Le Festival International de la Géographique (FIG) est organisé depuis 1990 à Saint-Dié-des-Vosges. Il accueille chaque année quelque 50.000 visiteurs et rassemble tant les spécialistes internationaux et ... [more ▼]

Le Festival International de la Géographique (FIG) est organisé depuis 1990 à Saint-Dié-des-Vosges. Il accueille chaque année quelque 50.000 visiteurs et rassemble tant les spécialistes internationaux et que les simples amateurs de culture et d’animation. Conférences, débats, tables rondes, cafés géographiques, expositions, foire du livre, salon de la géomatique, films… tout dans la ville et durant 3 jours est consacré – gratuitement – à la présentation des dernières découvertes de la recherche scientifique en géographie. Chaque année, un pays invité est à l’honneur. En 2016, c’est la Belgique ; de sorte que les chercheurs, les enseignants et les entreprises publiques et privées belges sont spécialement invités à participer à cette manifestation. La présentation faite durant la journée BeGeo du 3 mars à Bruxelles aura pour but de présenter les conditions de participation et d’inviter les partenaires belges au Salon de la Géomatique organisé durant le Festival International de la Géographie du 30 septembre au 2 octobre 2016. [less ▲]

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See detailMetamorphosing cultural patterns: Cassirer in the steps of Warburg on Culture Theory
Hagelstein, Maud ULg

Conference (2016, March 03)

My argument stems from a reading of the fifth study in Cassirer’s The Logic of the Cultural Sciences (1942), devoted to the “Tragedy of Culture.” I contend that this fifth study resolves an observable ... [more ▼]

My argument stems from a reading of the fifth study in Cassirer’s The Logic of the Cultural Sciences (1942), devoted to the “Tragedy of Culture.” I contend that this fifth study resolves an observable indecision in Cassirer’s position on cultural productions: to lead man toward greater happiness and freedom, should one strive to uphold traditional forms, or should one abandon old models and create new ones? I believe that Cassirer’s consideration of art historian Aby Warburg’s works (1866-1929) constitutes a defining moment in understanding his answer to that question. This fifth study illustrates the profound impact of Warburg’s model for understanding culture on Cassirer’s philosophy. Contrary to the claims of some exegetes, Cassirer and Warburg’s theoretical positions on the matter are very close. Cassirer’s treatment of the reception of artistic forms (he argues that form reception is never merely a passive act) follows, point by point, Warburg’s theory of the survival (Nachleben) of artistic motifs. [less ▲]

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See detailAnticoherence of spin states with point-group symmetries
Baguette, Dorian ULg; Damanet, François ULg; Giraud, Olivier et al

Poster (2016, March 02)

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana ... [more ▼]

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana represen- tation of spin states in terms of points on the unit sphere, we analyze the consequences of a point-group symmetry in their arrangement on the quantum properties of the corresponding state [1]. We focus on the identi cation of anticoherent states (for which all reduced density matrices in the symmetric subspace are maximally mixed) associated with point-group-symmetric sets of points. We provide three di erent characterizations of anticoherence and establish a link between point symmetries, anticoherence, and classes of states equivalent through stochastic local operations with classical communication. We then in- vestigate in detail the case of small numbers of qubits and construct in nite families of anticoherent states with point-group symmetry of their Majorana points, showing that anticoherent states do exist to arbitrary order. [1] D. Baguette et al., Phys. Rev. A 92, 052333 (2015). [less ▲]

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See detailReversal of Long-Term Trends in Ethane Identified from the Global Atmosphere Watch Reactive Gases Measurement Network
Helmig, Detlev; Buchmann, Brigitte; Carpenter, Lucy et al

Poster (2016, March 02)

Reactive gases play an important role in climate and air pollution issues. They control the self-cleansing capability of the troposphere, contribute to air pollution and acid deposition, regulate the ... [more ▼]

Reactive gases play an important role in climate and air pollution issues. They control the self-cleansing capability of the troposphere, contribute to air pollution and acid deposition, regulate the lifetimes and provide tracers for deciphering sources and sinks for greenhouse gases. Within GAW, the focus is placed on long-term, high-quality observations of ozone (O3), carbon monoxide (CO), volatile organic compounds (VOC), nitrogen oxides (NOx), and sulfur dioxide (SO2). More than 100 stations worldwide carry out reactive gases measurements with data reported to two World Data Centers. The reactive gases program in GAW cooperates The WMO GAW Reactive Gases Program with regional networks and other global monitoring initiatives in order to attain a complete picture of the tropospheric chemical composition. Observations are being made by in-situ monitoring, measurements from commercial routine air-crafts (e.g. IAGOS), column observations, and from flask sampling networks. Quality control and coordination of measurements between participating stations are a primary emphasis. GAW reactive gases data in rapid delivery mode are used to evaluate operational atmospheric composition forecasts in the EU Copernicus Atmospheric Monitoring Service. Oversight of the program is provided by GAW-WMO coordinated Reactive Gases Scientific Advisory Committee (RG-SAG). [less ▲]

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See detailEvaluer les connaissances et savoir-faire en matière de recherche d’informations scientifiques : comment faire avec de grands groupes d’étudiants en bachelier ?
Vandenput, Sandrina ULg; Crahay, Vinciane ULg; Piazza, Aurélie ULg et al

Conference (2016, March 01)

Au terme du cours consacré à la recherche d’informations scientifiques - au programme des bacheliers de la Faculté de Médecine vétérinaire et de la Faculté de Psychologie, Logopédie et des Sciences de ... [more ▼]

Au terme du cours consacré à la recherche d’informations scientifiques - au programme des bacheliers de la Faculté de Médecine vétérinaire et de la Faculté de Psychologie, Logopédie et des Sciences de l’Éducation (Université de Liège) - les étudiants doivent avoir une vue d’ensemble de la publication scientifique et être capables de (i) mener de manière autonome une recherche d’informations et (ii) de citer correctement leurs sources en respectant des normes bien précises lors de la rédaction de documents. L’évaluation de ce cours est contraignante car il s’agit de cohortes d’étudiants de plus en plus grandes (> 300 étudiants par cursus). Comment évaluer les connaissances ainsi que les savoir-faire de grands groupes d’étudiants ? Jusqu’alors l’examen se composait de questions ouvertes et nécessitait que chaque étudiant ait à sa disposition un ordinateur connecté à Internet. Cette méthode requérait une logistique importante avant et pendant l’examen ainsi que des semaines de correction. Plusieurs alternatives à cette évaluation ont alors été envisagées : travail individuel, travail de groupe, questionnaire à choix multiple… mais elles ne répondaient pas aux exigences fixées par les compétences à évaluer. La piste retenue pour cette nouvelle année académique reste contraignante du point de vue organisationnel (ordinateur pour chaque étudiant) mais permet une correction standardisée, automatisée, fiable et rapide. En effet, le questionnaire combine désormais des questions à choix multiple (QCM ; jusqu’à 9 propositions de réponses) et des questions à choix large (QCL ; jusqu’à 999 propositions). Le QCL présente l’avantage d’être proche de l’évaluation à l’aide de questions ouvertes sans les désavantages de la correction. Nous proposons de présenter ce dispositif évaluatif ainsi que ses avantages et inconvénients par rapport à d’autres méthodes d’évaluation. [less ▲]

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See detailLe manuel : pourquoi ? comment ?
Pochet, Bernard ULg

Conference (2016, March 01)

The aim of this communication is to present the objective the tools used to perform, meet objectives and overcome technical constraints

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Peer Reviewed
See detailMobiliser la culture du pays d’origine, un défi pour l’intégration des migrants?
Mescoli, Elsa ULg; Gsir, Sonia ULg

Conference (2016, March)

La culture constitue pour les migrants et leurs pays d’origine un moyen de maintenir des liens réciproques après la migration. Mais quels sont les enjeux de la mobilisation de la culture d’origine pour ... [more ▼]

La culture constitue pour les migrants et leurs pays d’origine un moyen de maintenir des liens réciproques après la migration. Mais quels sont les enjeux de la mobilisation de la culture d’origine pour l’intégration des migrants dans leurs nouveaux pays de résidence ? Cette présentation analyse le déploiement de la culture du pays d’origine à trois niveaux : celui des pratiques quotidiennes des migrants, des politiques d’intégration et de diaspora et enfin, le niveau des associations, en particulier les centres culturels établis en Europe par les pays d’origine des migrants. Les pratiques culturelles des migrants et les actions et institutions culturelles mises en place par les pays d’origine sont confrontées au cadre légal européen en matière de diversité culturelle mais aussi aux politiques et discours sur l’intégration des migrants. La perspective à la fois anthropologique et sociologique adoptée révèle les processus de domination culturelle qui sont à l’œuvre. Elle permet aussi de questionner l’idée d’identité culturelle en montrant le dynamisme qui caractérise les cultures mais aussi la créativité des communautés locales dans un environnement globalisé. Finalement, on constate qu’une variété de facteurs est en jeu dans les processus d’intégration des migrants, que les dynamiques de la culture elle-même déterminent des appartenances multiples et aussi que les identités se développent au sein des interactions entre cultures. Si on ne peut établir de lien causal et univoque entre les pratiques culturelles liées au pays d’origine et l’intégration des migrants dans le pays de résidence, on peut par contre se référer à la notion d’ethnicité et à sa fonction politique (Comaroff et Comaroff, 2009). [less ▲]

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Peer Reviewed
See detailClassifying simulated wheat yield responses to changes in temperature and precipitation across a european transect
Fronzek, S.; Pirttioja, N.; Carter, T. R. et al

Conference (2016, March)

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Peer Reviewed
See detailDevelopment of a translation stage for in situ non-invasive analysis and high resolution imaging
Strivay, David ULg; Clar, Mathieu ULg; Rakkaa, Saïd ULg et al

Poster (2016, March)

Non-invasive imaging techniques and analytical instrumentation for cultural heritage object studies have undergone a tremendous development over the last years. Many new miniature and/or handheld systems ... [more ▼]

Non-invasive imaging techniques and analytical instrumentation for cultural heritage object studies have undergone a tremendous development over the last years. Many new miniature and/or handheld systems have been developed and optimized. Nonetheless, these instruments are usually used with a tripod or a manual position system. This is very time consuming when performing point analysis or 2D scanning of a surface. The Centre Européen d’Archéométrie (CEA) has build a translation system made of pluggable rails of 1 m long with a maximum length and height of 3 m. Three motors embedded in the system allow the platform to be moved along these axis, toward and backward from the sample. The rails hold a displacement system, providing a continuous movement. Any position can be reached with a reproducibility of 0.1 mm. The displacements are controlled by an Ethernet connection through a laptop computer running a multiplatform homemade software written in JAVA. This software allows a complete control over the positioning using a simple, unique, and concise interface. Automatic scanning can be performed over a large surface of 3 meters on 3 meters. The Ethernet wires provide also the power for the different motors and, if necessary the detection head. The platform has been originally designed for a XRF detection head (with its full power alimentation) but now can accommodate many different systems like IR reflectography, digital camera, hyperspectral camera, Raman probes, etc. The positioning system can be modified to combine the acquisition software of the imaging or analytical techniques and the positioning software. [less ▲]

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See detailNovel composite heterozygous mutation of the receptor for hCG and LH leading to male disorder of sexual development
Potorac, Iulia ULg; FUDVOYE, Julie ULg; GAILLEZ, Stephanie ULg et al

in Abstract book - 17th World Congress of Gynecological Endocrinology (2016, March)

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See detailDynamical thermalization in Bose-Hubbard systems
Schlagheck, Peter ULg; Shepelyansky, Dima L.

Conference (2016, March)

A bosonic many-body system can exhibit the Bose-Einstein distribution in its single-particle eigenstates not only if it is coupled to a heat and particle reservoir, but also if it is subject to a two-body ... [more ▼]

A bosonic many-body system can exhibit the Bose-Einstein distribution in its single-particle eigenstates not only if it is coupled to a heat and particle reservoir, but also if it is subject to a two-body interaction of moderately low strength which couples the single-particle eigenstates with each other. We numerically verify this dynamical thermalization conjecture within disordered Bose-Hubbard rings of finite size whose parameters are chosen such that the dynamics of the system can be expected to be ergodic [1]. This allows one to associate with each many-body eigenstate of the Bose-Hubbard system well-defined (positive or negative) values for the effective temperature and the effective chemical potential which depend on the energy per particle of the eigenstate under consideration [1]. With this information one can then predict the populations of single-particle eigenmodes within each many-body eigenstate of the system according to the Bose-Einstein distribution, without knowing more details about the quantum dynamics of the many-body system. [less ▲]

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See detailBad News in Service Encounters: Ideas and Insights
Delcourt, Cécile ULg; Gremler, Dwayne

Conference (2016, March)

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See detailInfection expérimentale de porcs, par voie intraveineuse ou orale, avec une souche du virus de l’hépatite E (HEV) de sanglier, une souche de HEV porcine et une souche de HEV de sanglier préalablement passée en modèle porcin
Thiry, Damien ULg; Rose, Nicolas; Mauroy, Axel ULg et al

Poster (2016, March)

La transmission zoonotique du HEV est particulièrement mise en cause dans les pays développés dans lesquels la transmission via les eaux usées est beaucoup moins fréquente que dans les pays en voie de ... [more ▼]

La transmission zoonotique du HEV est particulièrement mise en cause dans les pays développés dans lesquels la transmission via les eaux usées est beaucoup moins fréquente que dans les pays en voie de développement. Des séroprévalences élevées sont observées chez certaines espèces animales dans plusieurs pays européens. Cette étude a porté sur la transmission potentielle au porc d\'une souche de HEV provenant du sanglier (WbHEV) par inoculation intraveineuse ou par voie orale et sur l’étude des conséquences de l’infection du porc par une souche de WbHEV, une souche de WbHEV précédemment passée chez le porc et une souche porcine de HEV après inoculation orale. Tout d\'abord, une infection par voie intraveineuse a été réalisée au cours de laquelle cinq porcelets ont été répartis en deux groupes. Le premier était constitué de trois porcs inoculés avec du WbHEV et le second, de deux porcs inoculés avec un foie de porc négatif envers le HEV. Tous les porcs ont été euthanasiés et autopsiés 8, 9 et 10 jours après l’inoculation. Cette première expérience avait pour objectif d’obtenir suffisamment de virus en vue de réaliser les inoculations par voie orale. Elle a également permis d’étudier l’infectivité d’une souche de HEV-3 provenant du sanglier chez le porc. Ensuite, une infection par voie orale a été réalisée sur 12 porcelets répartis en 4 groupes inoculés respectivement avec une souche de WbHEV, une souche de WbHEV précédemment passée chez le porc, une souche porcine de HEV et un foie de porc HEV négatif. Cette expérience a duré 56 jours. Les échantillons récoltés ont ensuite été analysés par qRT-PCR, ELISA, Western blot et histopathologie. Le nombre de porcs virémiques était plus faible après infection orale qu’après inoculation intraveineuse. Ce résultat contraste avec la présence du HEV dans les matières fécales des porcs au cours des deux expériences. Les résultats montrent également une propagation du virus dans différents organes après inoculation intraveineuse, mais pas après inoculation par voie orale. Cette étude fournit la première preuve expérimentale de la propagation précoce du virus dans l\'organisme après infection intraveineuse avec une souche de HEV provenant du sanglier et montre qu’une telle souche pourrait être naturellement transmise entre les sangliers et les porcs, mais aussi entre porcs et donc survivre dans la population porcine. [less ▲]

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