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See detailDéchéance de nationalité et terrorisme : quelle marge de manoeuvre pour l'Etat?
Wautelet, Patrick ULg

Conference (2015, October)

Cette présentation a pour objet de situer de manière critique les récentes interventions du législateur belge en matière de déchéance de la nationalité belge, en montrant quelles sont les limites ... [more ▼]

Cette présentation a pour objet de situer de manière critique les récentes interventions du législateur belge en matière de déchéance de la nationalité belge, en montrant quelles sont les limites internationales à l'action du législateur national. Le cadre législatif en vigueur en Belgiqe est analysé en particulier à la lumière de l'interdiction de discrimination [less ▲]

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See detailSILURIAN – DEVONIAN OF THE ORIENTAL ALGERIAN SAHARA: implication of new field data from Tassili n'Ajjer outcrops and Berkine Basin (SE, Algeria) for shale gas exploration.
Djouder, Hocine ULg; Boulvain, Frédéric ULg; Da Silva, Anne-Christine ULg et al

in EPC'2015 THE THIRTEENTH TUNISIAN PETROLEUM EXPLORATION & PRODUCTION CONFERENCE (2015, October)

The Silurian – Devonian succession have been deposited in wide sags and sub-basins in a cratonic setting, along the northwestern passive margin of the Gondwana during the opening of the proto-Tethyan ... [more ▼]

The Silurian – Devonian succession have been deposited in wide sags and sub-basins in a cratonic setting, along the northwestern passive margin of the Gondwana during the opening of the proto-Tethyan ocean. During this Siluro-Devonian Period, a high subsidence occurs stacked sediment bodies and organic-rich shales were deposited in many places that respectively form important hydrocarbon reservoirs and source rocks throughout North Africa basins and Arabia (Boot et al., 1998 ; Lüning et al., 2000), which lead Algeria to hold the fourth position in terms of the estimates of technically recoverable shale oil and shale gas resources, based on major basin assessment in the world (EIA, 2013). In the prolific Illizi and Berkine basins (western Ghadames, Algeria) a basin-wide approach is needed, especially with the new “shale gas and shale oil” frontier in the upcoming years, in order to capture regional trends and re-assessment on organic-rich (‘hot’) shale unites which in smaller-scale industrial studies are overlooked. Berkine Basin covers nearly 102.000 km2. This basin has been a thick sedimentary series of 7000 m corresponding to complex reservoirs but also black shales of the basal Silurian and Frasnian respectively major and secondary source rock systems. Wireline-logs from more than 146 (Berkine – Illizi Basins) Algerian petroleum exploration wells have been studies (Djouder et al., 2012; Djouder et al., 2014), and recently 03 months extensive field study of outcrops of the Siluro-Devonian sediments was carried out at the south margin (SE, Tassili n’Ajjer) of the basin. The following analysis incorporates biostratigraphic, ichnological, sedimentological and high resolution stratigraphic data, which provides a framework evolution from offshore to deltaic deposition for the Silurian then fluvial to normal-marine depositional conditions for the Devonian. A total of 06 short-term, third-order sequences can be identified for the Silurian deposits: (i) 'Hot Shale' Oued Imihrou Formation, organic-rich shales with carbonates nodules (Si-1); (ii) above is the Atafaïtafa Formation 500 to 650 m thick with HCS, gutter casts and Cruziana Ichnofacies (Si-2, Si-3); (iii) then overlaid by coarsening-shallowing-upward units. These sequences (Si-4, Si-5 & Si-6) with Storm-wave dominated and Skolithos Ichnofacies are interpreted to reflect deltaic origin. This delta is the result of a significant sea-level drop during the Upper Silurian (Beuf et al, 1971) but also from the high sedimentation rates prograding northwards (Eschard et al., 2005). Devonian deposit also can be divided into fourth third-order sequences (Dev-1 to 4), by the same previous analysis. The base of the cycle is the Caledonian unconformity linked to a tectonic event which affected most of the Gondwanan margin at the Silurian – Devonian boundary and a major relative sea-level fall (Eschard et al., 2005). Previous sequences defined from Tassili n’Ajjer outcrops are well recognized at the basin-scale (Berkine Basin) and can be correlated in the subsurface of the Illizi – Berkine basins (Djouder et al., 2012). Finally, the full depositional cycle for the Silurian – Devonian is reached and capped by the Frasnian maximum flooding surface, with black shales across North Africa (Algeria, western Libya and southern Tunisia) and which are also developed in many parts of the world (Lüning et al., 2003). [less ▲]

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See detailSociology of literature and sociocriticism
Saint-Amand, Denis ULg

Conference (2015, October)

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See detailHypogonadisme hypogonadotrope normosmique familial : identification d'une nouvelle mutation c.1664-2A> T du gène FGFR1
VALDES SOCIN, Hernan Gonzalo ULg; Pintiaux, Axelle ULg; LIBIOULLE, Cécile ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailSofosbuvir in combination with simeprevir +/- ribavirin in genotype 4 hepatitis C patients with advanced fibrosis or cirrhosis: a real-life experience from Belgium
Moreno, C; Lasser, L; DELWAIDE, Jean ULg et al

in Hepatology (Baltimore, Md.) (2015, October), 62(1), 746

Background: All-oral, interferon-free regimens that combine direct-acting antiviral drugs have significantly advanced the treatment of hepatitis C (HCV), especially for genotype 1(G1) patients. However ... [more ▼]

Background: All-oral, interferon-free regimens that combine direct-acting antiviral drugs have significantly advanced the treatment of hepatitis C (HCV), especially for genotype 1(G1) patients. However, efficacy and safety data of interferon-free regimens in HCV genotype 4 (G4) patients are scarce. In Belgium, Sofosbuvir (SOF) and Simeprevir (SMV) treatment is available since January 2015 for G4 patients with advanced fibrosis (F3-F4 METAVIR) for 12 weeks. Methods: analysis of HCV G4 patients receiving SOF and SMV treatment in Belgium. The aim of the study was to evaluate the safety and efficacy of the treatment. Results: 73 G4 patients were enrolled in this data collection including 32 (43.8%) patients with severe fibrosis F3 and 41(56.2%) cirrhotic patients. The study population comprised 58.9% male, 77.8% treatment experienced patients. Median age was 59 [51-66] years and 5 patients were HCV/HIV co-infected. 24 patients received the treatment associated with ribavirin, 11/32 (34.37%) of patients with advanced fibrosis and 13/41 (31.71%) of cirrhotic patients. In cirrhotic patients, median MELD and Child-Pugh score were 9 [7-12.5] and 5 [5-6], 46.2% had platelet below 100.000/mm and 28.6% had albumin below 35 g/L. W4 HCV RNA was undetectable in 31.25% (15/48). 9 of the 15 patients with undetectable W4 HCV RNA received RBV. At W12, 100% (23/23) had HCV RNA below the limit of quantification, with 6/23 still detectable. All SVR12 data will be available at the time of presentation. No patient experienced serious adverse event. Conclusions: these preliminary results in difficult-to-treat G4 HCV patients show that SOF/SIM +/- RBV treatment is safe and seems promising, in line with that was observed in G1 HCV patients. [less ▲]

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See detailValorisation de la biomasse pour des applications vers des marchés de niche
Richel, Aurore ULg

Conference (2015, October)

Dans le contexte économique actuel de notre société, il est reconnu que des alternatives et des compléments à la pétrochimie devront être développés dans un futur proche. L’une des solutions possibles ... [more ▼]

Dans le contexte économique actuel de notre société, il est reconnu que des alternatives et des compléments à la pétrochimie devront être développés dans un futur proche. L’une des solutions possibles réside dans le développement de procédés permettant de substituer les actuels produits pétro-sourcés par de nouveaux matériaux bio-basés issus de la biomasse. Sur base de ce constat, Gembloux Agro-Bio Tech et son laboratoire de Chimie Biologique Industrielle se positionnent sur cette thématique en abordant les aspects technico-économiques de transformation du végétal en une gamme de produits à haute valeur ajoutée à destination de divers secteurs applicatifs tels que les matériaux, le cosmétique, le pharmaceutique, etc. L'importance de l'agronomie et des techniques agricoles, combinée à une gestion appropriée des déchets en circuits courts, sont deux piliers discutés dans ce exposé et illustrés au travers de divers exemples stratégiques. [less ▲]

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See detailPlankton ecosystem response to the decadal variation of winter intensity in the Mediterranean Sea : a long-term study (1979-2014)
Goffart, Anne ULg; Collignon, Amandine ULg; Hecq, Jean-Henri ULg et al

Poster (2015, October)

In the Mediterranean Sea, several studies with distinct data sets indicate that the pelagic ecosystem underwent periods of change in the late 1980s and in the early 2000s. Here we used a unique long-term ... [more ▼]

In the Mediterranean Sea, several studies with distinct data sets indicate that the pelagic ecosystem underwent periods of change in the late 1980s and in the early 2000s. Here we used a unique long-term time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) from 1979 and 2014 to explore the synchrony between changes in environmental conditions and phyto- and zooplankton dynamics. We identified an almost decadal, long-term variability in winter intensity, with three distinct periods: the 1980s (1979-1988), the 1990s (1989-1998) and the 2000s (1999-2014), which were characterized by moderate, mild and highly variable winters, respectively. We pointed out how the decadal changes in winter intensity affected (i) the duration and intensity of phyto- and zooplankton blooms, (ii) the mean yearly biomasses, and (iii) the nature of the assemblages. High phyto- and zooplankton biomasses were observed in years characterized by moderate and severe winters, and low phyto- and zooplankton abundances were recorded in years with mild winters. Moderate/severe and mild winters were favorable for diatoms and gelatinous zooplankton, respectively. Focusing on meroplanktonic species, we explored ecological consequences of decadal variations observed in the Bay of Calvi for resource management. We highlighted parallelisms with other European seas. [less ▲]

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See detailOnychomycosis: is it possible to increase the cure rate?
Hayette, Marie-Pierre ULg

in Mycoses (2015, October), 58(suppl 4), 35

Onychomycosis represent about 50% of nails disorders in the world with a very variable prevalence depending of the countries considered. Dermatophytes, non-dermatophyte molds and Candida sp. are the main ... [more ▼]

Onychomycosis represent about 50% of nails disorders in the world with a very variable prevalence depending of the countries considered. Dermatophytes, non-dermatophyte molds and Candida sp. are the main causing agents. A rapid and accurate diagnosis is essential in order to give an adequate treatment to the patient. Generally, a combination of microscopy and culture is used for laboratory diagnosis. However, microscopy does not always allow the distinction between yeasts or filamentous fungi, culture takes generally about a week before identification and the result is compromised if there is contamination by not relevant fungi. Therefore commercially available PCR-based methods have been developed in order to provide a rapid and accurate identification of dermatophytes and yeasts in nails samples. Combination of microscopy and PCR may provide a rapid and specific diagnosis in 2 working days. However this methodology is still not widely used by laboratories because of the high cost. Furthermore, this technology can detect DNA from dead fungi and therefore is not suitable for assessment of treatment efficacy. Onychomycosis therapy depends on different factors such as the causative agent, the number of nails and degree of nail involvement, the type of onychomycosis, potential drug interactions or drug intolerance and a failure to previous treatments. Oral and topical antifungals are mostly used separately or in combination. Oral therapy includes azoles (itraconazole, fluconazole) and/or allylamine (terbinafin), this latter being the most frequently prescribed antifungal for treatment of onychomycosis in North America and Europe. Topical amorolfine and ciclopirox formulations can be used alone in mild cases or in case of intolerance to oral antifungals. However, one of the biggest problems of therapy for onychomycosis is the high frequency of relapse which concerns about 20 to 40% of the patients treated by oral antifungals. Different strategies have been developed to overcome this problem amongst which are: optimization of the dosing regimens (continuous vs pulse therapy) or therapy duration, combination therapy (nail debridement + antifungals, oral + topical drugs, 2 oral drugs), improving drug delivery (use of physical or chemical enhancers, and modification of the pharmacological formulation for increasing drug uptake). Some strategies such as combination therapy (oral + topical) have demonstrated enhanced efficacy and should be recommended in case of poor efficacy of the initial treatment or in case of extended infection. Prophylactic topical therapy implemented after completion of oral treatment has been shown to delay relapse. Preventive measures such as treatment of concurrent tinea pedis and/or infected family members and regular cleaning of bathroom and shower floors can help to reduce the risk of reinfection particularly when a dermatophyte is the causative agent. In conclusion, treatment for onychomycosis is associated with frequent relapse. Consequently, follow-up is mandatory and combination therapy can be necessary in case of relapse or resistance to treatment. Patients should also be aware of the preventive hygiene measures to apply in order to decrease the risk of reinfection. New strategies improving treatment efficacy are promising but their efficacy have still to be demonstrated in comparative clinical trials before their implementation in therapy. [less ▲]

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See detailTriclosan retardes development of Sheepshead minnow (Cyprinodon variegatus)
Dussenne, Mélanie ULg; Frederich, Bruno ULg; Das, Krishna ULg et al

Conference (2015, October)

The aquatic environment represents the final sink for many chemicals, including bactericidal agents. Among them Triclosan (TCS), with his chemical structure similar to thyroid hormones (THs), may have ... [more ▼]

The aquatic environment represents the final sink for many chemicals, including bactericidal agents. Among them Triclosan (TCS), with his chemical structure similar to thyroid hormones (THs), may have adverse effects on the thyroid system. The study we carried out aims to evaluate the effects of TCS exposure on development of Cyprinodon variegatus, a fish model used in ecotoxicological studies. We investigated the potential effects of TCS on C. variegatus during two key periods; embryonic development and metamorphosis. We exposed eggs and larvae to environmental relevant concentrations. We showed that TCS had no effect on reproduction parameters, such as egg fertility or survival rate of larvae. However, we highlighted the fact that hatching of exposed larvae was delayed of around 6 to 13 hours compared to control embryos. During the larval phase, measurements of THs levels were performed. We showed that TCS affected the typical ontogenic variations of the whole body thyroid hormones concentrations during metamorphosis. As THs are known to control somatic growth and development, we tested the effects of TCS exposure on morphological development. We observed no deformity or malformation, but we revealed a developmental retardation in larvae exposed to TCS, of around 18 to 32 hours. Such a developmental delay had never been highlighted in previous studies on TCS exposed fish. We hypothesize that the disruption of THs homeostasis affects the timing of the start of metamorphosis. As a consequence, exposed larvae showed an extended larval phase compared to the control group. The harmful effects of TCS on physiology and development are a major concern, as marine organisms are constantly exposed to it. Furthermore, strong connections exist between thyroid and reproductive system, which might have deleterious effects on population dynamics. [less ▲]

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See detailAnthocyanin-rich blackcurrant juice induces a redox-sensitive caspase 3-related pro-apoptotic effect in leukemia Jurkat cells: role of delphinidin-3-O-glucoside and delphinidin-3-O-rutinoside
Leon-Gonzalez; Sharif, T; Kayali, A et al

in 7th International Conference on Polyphenols and Health (2015, October)

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See detailSoil production and hillslope transport in mid-latitudes during the last glacial-interglacial cycle: A combined data and modelling approach in northern Ardennes
Bovy, Benoît ULg; Braun, Jean; Demoulin, Alain ULg

Conference (2015, October)

The relative efficiency of various hillslope processes through Quaternary glacial-interglacial cycles in the mid-latitudes is not well constrained. Based on a unique set of topographic and soil thickness ... [more ▼]

The relative efficiency of various hillslope processes through Quaternary glacial-interglacial cycles in the mid-latitudes is not well constrained. Based on a unique set of topographic and soil thickness data in the Ardennes (Belgium), we combine the new CLICHE model of climate-dependent hillslope evolution with an inversion algorithm in order to get deeper insight into the ways and timing of hillslope dynamics under one such climatic cycle. We simulate the evolution of a synthetic hill reproducing the terrain attribute distributions of the hillslopes of a ~2500 km2 real area under a simple two-stage 120-kyr-long climatic scenario with linear transitions. The inversion method samples a misfit function in the model parameter space, based on estimates of the fit of topographic derivative distributions in classes of soil thickness and of the relative frequencies of the predicted soil thickness classes. Though the inversion results show convergence patterns for several parameters, no unique solution emerges. We obtain five clusters of good fits, whose centroids are taken as acceptable model solutions. Based on the predicted time series of average denudation rate and soil thickness, plus snapshots of the soil distribution at characteristic times, we compare these solutions with independent data not involved in the misfit function and identify the most realistic one. Providing first-order estimates of several parameters that compare well with published data, it shows that denudation rates increase dramatically at both warm-cold and cold-warm transitions when the mean annual temperature passes through the [0, -5°C] range. It also underlines the overwhelming importance of gelifluction in transporting soil and shaping hillslopes. [less ▲]

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See detailFiber-optic Temperature Profiles Analysis for Closed-loop Geothermal Systems - A Case Study
Radioti, Georgia ULg; Delvoie, Simon ULg; Sartor, Kevin ULg et al

in Second EAGE Workshop on Geomechanics and Energy: The ground as energy source and storage (2015, October)

In order to study the behaviour of shallow closed-loop geothermal systems four borehole heat exchangers equipped with fiber optics were installed on the campus of the University of Liege (Liege, Belgium ... [more ▼]

In order to study the behaviour of shallow closed-loop geothermal systems four borehole heat exchangers equipped with fiber optics were installed on the campus of the University of Liege (Liege, Belgium) over a surface area of 32m². This paper presents the analysis of continuous, high-resolution temperature profiles measured along the boreholes length. The undisturbed ground temperature measurements indicate heat loss from ground structures located close to the boreholes. A 3D numerical model is presented to reproduce the measured temperature profiles. Temperature profiles during hardening of the grouting material indicate extended fractured zones in the rock mass. Temperature measurements during the recovery phase of a Distributed Thermal Response Test indicate the succession of rock layers with different mineral content. The results are in good agreement with those of the borehole televiewer logging method. The presented analysis could provide information on bedrock heterogeneity, on the anisotropic thermal behaviour of the rock mass and on the ground temperature variations due to heat loss from ground structures. These information could significantly contribute to the long-term behaviour prediction of the geothermal system and the geothermal reservoir potential. [less ▲]

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See detailAnthropogenic particles in stomachs of anchovies (Engraulis encrasicolus) related to gill rakers morphology
Collard, France ULg; Das, Krishna ULg; Gilbert, Bernard ULg et al

in Proceedings of In the Wake of Plastics, Venice, October 13-15, 2015 (2015, October)

Anthropogenic debris (AB) contaminate oceans and affect marine organisms in several ways. Plastic production is constantly increasing and it is estimated that 10% of this production end in the seas. As a ... [more ▼]

Anthropogenic debris (AB) contaminate oceans and affect marine organisms in several ways. Plastic production is constantly increasing and it is estimated that 10% of this production end in the seas. As a consequence, plastic is considered as an emerging contaminant and ingestions by organisms are increasingly reported. Microdebris (< 5mm) are available for a high range of organisms, including planktivorous fish, such as the European anchovy (Engraulis encrasicolus). Planktivorous fish have a particular gill basket, with long and tight gill rakers, related to their diet. Upon these gill rakers, small structures called denticles are present. These gill rakers act as a net to trap organic particles and AB. The aim of our study was to correlate sizes of AB ingested with the mesh constituted by the gill rakers and associated structures. Fifteen stomach contents were analyzed by Raman spectroscopy and particles were measured. Five gill arches were observed with a scanning electron microscope. Cellulose fibers and microplastics were the most AB ingested. Comparing to other Clupeiformes (pilchard and Atlantic herring), anchovies have more denticles on each gill rakers (personal data). AB ingestion by fish is poorly studied and impacts of AB are not much understood. Clupeiformes play a major role in marine ecosystems and is the most consumed order by humans. As the branchial basket constitutes a food selective apparatus, more morphological studies dealing with AB ingestion on Clupeiformes are needed. [less ▲]

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See detailPrimeros datos sobre las interacciones planta-insecto del yacimiento de La Val (Estadilla, Huesca, NE Spain)
Moreno-Domiguez, Rafael; Cascales-Miñana, Borja ULg; Santos, Artai I et al

in Proceedings of the XXXI Annual Meeting of the Spanish Society of Palaeontology (abstract book) (2015, October)

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See detailNew genetic cause of gigantism and FIPA
Rostomyan, Liliya ULg; Daly, Adrian ULg; Trivellin, G et al

in Abstract book - 25th meeting of the Belgian Endocrine Society (2015, October)

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See detailIs the Darwin´s “Abominable Mystery” still a mystery?
Cascales-Miñana, Borja ULg; Cleal, Chris J.; Gerrienne, Philippe ULg

in Proceedings of the XXXI Annual Meeting of the Spanish Society of Palaeontology (abstract book) (2015, October)

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See detailThe antibiotic resistance in the environment
Bardiau, Marjorie ULg

Conference (2015, October)

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See detailTime Ordering Shuffling for Improving Background Subtraction
Laugraud, Benjamin ULg; Latour, Philippe ULg; Van Droogenbroeck, Marc ULg

in Advanced Concepts for Intelligent Vision Systems (ACIVS) (2015, October)

By construction, a video is a series of ordered frames, whose order is defined at the time of the acquisition process. Background subtraction methods then take this input video and produce a series of ... [more ▼]

By construction, a video is a series of ordered frames, whose order is defined at the time of the acquisition process. Background subtraction methods then take this input video and produce a series of segmentation maps expressed in terms of foreground objects and scene background. To our knowledge, this natural ordering of frames has never been questioned or challenged. In this paper, we propose to challenge, in a prospective view, the natural ordering of video frames in the context of background subtraction, and examine alternative time orderings. The idea consists in changing the order before background subtraction is applied, by means of shuffling strategies, and re-ordering the segmentation maps afterwards. For this purpose, we propose several shuffling strategies and show that, for some background subtraction methods, results are preserved or even improved. The practical advantage of time shuffling is that it can been applied to any existing background subtraction seamlessly. [less ▲]

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See detailWhere is the ancient harbour of Utica ? Geoarchaeology and palaeoenvironment of the Medjerda delta (Tunisia)
Pleuger, Elisa ULg; Abichou, Hakim; Gadhoum, Ahmed et al

Poster (2015, October)

Ancient authors mention Utica as a maritime and port city and estimate its origin around the 11th c. BC. However, in the present state of research, no archaeological evidence is earlier than the 9th c. BC ... [more ▼]

Ancient authors mention Utica as a maritime and port city and estimate its origin around the 11th c. BC. However, in the present state of research, no archaeological evidence is earlier than the 9th c. BC, and the location of the Phoenician and Roman port infrastructures remains unknown. Today, the ancient city is located on a promontory in the heart of the Medjerda delta, 10 km inland. This project proposes an interdisciplinary effort to understand the Medjerda delta landscape changes during the Holocene. It starts from an archaeological problem and proposes the contribution of geoarchaeology to the understanding of the relationship between ancient societies and their environment. The fluvial palaeoenvironments and sedimentary processes are studied through the mechanical extraction of cores (15-20 m deep) to reach the early Holocene. Selected sediment samples are then studied in laboratory, using different and complementary approaches. First results permitted to draw an hypothesis of the coastline during Antiquity and to bring out the evidence of an intense sedimentation event post 10th c. BC. The location of port infrastructures will bring initial answers to the question of the foundation of the city. The study of river palaeoenvironments of the Medjerda delta during the Holocene aim at a better understanding of the nature of the settlement, as well as the function of the city of Utica over time. This study will also assess the impact of the ancient city on the environment and understand how the city adapted to the mobility of this Mediterranean delta. Furthermore, the analysis of sedimentary processes causing the filling of the harbour basin will lead to speculation about the causes of the abandonment of the structures and more generally the decline of the city in favor of Carthage. It will also examine whether natural or anthropogenic factors have influenced this deltaic progradation over the centuries. [less ▲]

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See detailPotential damping of extreme floods in the river Meuse between Ampsin (B) and the Belgian-Dutch border
Bruwier, Martin ULg; Archambeau, Pierre ULg; Erpicum, Sébastien ULg et al

in Lenders, H.J.R.; Collas, F.P.L.; Geerling, G.W. (Eds.) et al Bridging gaps between river science, governance and management. Book of Abstracts NCR-Days 2015 (2015, October)

In the framework of the Interreg IVB project AMICE, hydraulic modelling of floods in the river Meuse was performed by coordinating existing models (Dewals et al. 2012a). The influence of climate change ... [more ▼]

In the framework of the Interreg IVB project AMICE, hydraulic modelling of floods in the river Meuse was performed by coordinating existing models (Dewals et al. 2012a). The influence of climate change scenarios was incorporated indirectly in the simulations through a transnational hydrological scenario (Drogue et al. 2010; Dewals et al. 2013). For a “wet” future climate, this scenario assumes that the peak discharge Q100 of the 100-year flood would increase by 15 % for the time horizon 2021-2050 and by 30 % for the time horizon 2071-2100. However, the design discharge currently used for planning in the Netherlands is higher than those considered to date in the AMICE project. From this perspective, it becomes relevant to analyse flood scenarios corresponding to a peak discharge above Q100+30 %, referred to hereafter as an “extreme” flood. The aim of the study is to give an appreciation of the potential damping of one extreme flood scenario along the river Meuse between Ampsin (Belgium) and the Belgian-Dutch border (Figure 1). This analysis is based on the hydraulic model WOLF 2D (Erpicum et al. 2010) applied to a coarse grid with simplifications in the schematisation. The hydraulic model WOLF 2D has been already used in several studies to simulate floods (Ernst et al. 2010; Beckers et al. 2013, Bruwier et al. 2015, Detrembleur et al. 2015). The coarsening of the grid for simulating the extreme flood scenario is necessary to preserve the computational efficiency, since both the total flood duration and the inundation extents (hence the number of grid cells) increase considerably between the Q100 + 30 % scenario considered previously and the extreme scenario considered here. [less ▲]

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See detailLa participation et ses distorsions: du malentendu aux bénéfices secondaires
Italiano, Patrick ULg

in Bingen, Aline; Pilet, Jean-Benoît (Eds.) L'art de la participation (2015, October)

Les dispositifs participatifs, dans la vie réelle, sont souvent soit verrouillés soit déconnectés de la décision finale sur laquelle ils sont censés porter. Cela peut avoir des effets délétères sur les ... [more ▼]

Les dispositifs participatifs, dans la vie réelle, sont souvent soit verrouillés soit déconnectés de la décision finale sur laquelle ils sont censés porter. Cela peut avoir des effets délétères sur les publics que ces dispositifs voulaient impliquer. Il n'est pas rare que l'on donne le label "participation" à des processus dont la nature est mieux décrite par d'autres concepts. En définitive, c'est probablement dans des dispositifs centrés sur les personnes, et non sur des prises de décisions politiques, que l'exercice participatif est le plus susceptible d'avoir un effet positif univoque. [less ▲]

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See detailSURFACE ENGINEERING FOR PARTS MADE BY ADDITIVE MANUFACTURING
Nutal, Nicolas; Rochus, Pierre ULg; Collette, Jean-Paul et al

in 66th International Astronautical Congress (2015, October)

the surface preparation of metal parts made by additive manufacturing (AM). AM is a technology of choice for manufacturing of parts with complex shapes (heat exchangers, RF supports, optical parts…) and ... [more ▼]

the surface preparation of metal parts made by additive manufacturing (AM). AM is a technology of choice for manufacturing of parts with complex shapes (heat exchangers, RF supports, optical parts…) and integrated functions such as conformal cooling channels, clips, hinges, etc. This opens the door for lightweight parts which are of prime importance for space applications. The potential of the AM technologies is however impeded by the quite rough surface finish that is observed on the as-manufactured parts. It is known that such a finish is likely to impact the performance of the parts. Several post-treatment techniques can be applied to improve the surface condition of the AM parts. However, so far, the influence of the successive post-processing steps on the final properties is not well established. Therefore, a better understanding of the impact of surface characteristics on the material behaviour is needed to expand the use of AM for high performance parts. The objective of this study, supported by ESA, is to propose and evaluate various surface finishing techniques for parts made by the AM technologies, in order to check their compatibility, evaluate their properties and derive guidelines for future applications. CRM is the prime proposer of this study and is in charge of the surface treatment and characterisations. Sirris additive manufacturing facilities are used to produce the parts. Thales Alenia Space and Walopt are included into the industrial team to provide concrete application cases. The study focuses on metals. Two metals under study are presented here: AlSi10Mg and Ti6Al4V. This paper is devoted to the early results of the first steps of surface preparation, namely material removal from the surface of the produced parts in order to improve their surface properties. As a first phase, tribo-finishing (TF) is tested on prototype parts to check its capabilities. Surface and volume parameters are analyzed, namely achieved roughness, material removal rate, location of removed material. The limitations in terms of geometry and applicability are discussed as well. These first observations should serve as guidelines for further application of AM for the design of parts used in space industry. [less ▲]

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See detailLe développement de la pensée algébrique : quelles différences entre les raisonnements mis en place par les élèves avant et après l'introduction de l'algèbre ?
Demonty, Isabelle ULg; Fagnant, Annick ULg; Vlassis, Joëlle

in Actes du congrès EMF 2015. Pluralités culturelles et universalité des mathématiques : enjeux et perspectives pour leur enseignement et leur apprentissage. (2015, October)

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See detailEtude moléculaire du gène AIP sur plus de 1400 individus atteints d'adénome hypophysaire
CASTERMANS, Emilie ULg; Auriemma, R; Rostomyan, Liliya ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailFonds 'vautours', contentieux des dettes souveraines et droit de propriété
Wautelet, Patrick ULg

Conference (2015, October)

Cette présentation a pour objectif de contextualiser la loi du 12 juillet 2015 visant à réprimer l'action des fonds dits 'vautours' en offrant une première analyse critique de la loi, principalement au ... [more ▼]

Cette présentation a pour objectif de contextualiser la loi du 12 juillet 2015 visant à réprimer l'action des fonds dits 'vautours' en offrant une première analyse critique de la loi, principalement au regard de la protection internationale du droit de propriété [less ▲]

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See detailEpidemiological aspects and genotypic characterization of T.violaceum strains collected during a Belgian National survey on anthropophilic tinea
SACHELI, Rosalie ULg; Dekkers, Charlotte; GRAIDE, Hélène ULg et al

in Mycoses (2015, October), 58(Supplement 4), 189

Objectives The last two years, clinical cases of tinea capitis caused by Trichophyton violaceum (T. violaceum), have been identified in Belgium. To better understand the emergence of this species in the ... [more ▼]

Objectives The last two years, clinical cases of tinea capitis caused by Trichophyton violaceum (T. violaceum), have been identified in Belgium. To better understand the emergence of this species in the population, the Belgian National Reference Center (NRC Liège) launched a one-year national survey in 2013. Epidemiological aspects and genotypic characterization of the strains were included. Methods The study was conducted from March 2013 up to February 2014. All Belgian laboratories were asked to send M. audouinii and T. violaceum strains isolated from hair to the NRC with a form to fill in including epidemiological data. The fungal strains were identified by microscopy or ITS sequencing in case of doubtful identification. The genotypic analysis was performed by the DiversiLab® system (bioMérieux) for DNA fingerprinting and analysis. Epidemiological data were analyzed with the help of a biostatistician. Results Amongst the collected isolates, 23 strains were confirmed as T.violaceum (results concerning the 116 M. audouinii strains have already been reported). Analysis of the epidemiological characteristics of the infected population shows that the main age category concerns 0-4 year-old children (n=9, 39,1%) with a sex-ratio M/F of 1.875. Data concerning the geographic origin of the family were present in 82,6% of the cases and reveal that patients were mainly of Ethiopian origin (n=8, 57,9% of known cases). One patient was also from Burundi showing that T. violaceum strains probably circulate mainly in East Africa. The genotypic analysis led to the distinction of 2 variants of T. violaceum. The major group was composed of 17 strains which were mainly collected in the North of Belgium and included also the reference strain (18/23, 83,3%). The other group (6 strains) was close to the major group but the analysis of the spectral superposition showed some differences between these two groups, defining two distinct variants of T. violaceum in the Belgian population. This second variant was mainly recovered from South Belgium (5/6, 83,3%). No correlation could be made between the genotypic group and a particular ethnical origin as Ethiopian subjects were found in both groups. Conclusion The DiversiLab® system proved to be an efficient method to investigate the molecular epidemiology of dermatophytes infections as reported previously for M. audouinii. These results show that two distinct isolates co-exist in Belgium providing evidence of genetic heterogeneity and a possible spread of one genotypic variant in a restricted geographic area or the co-existence of two variants circulating in different African communities. However, no clear correlation could be established between the appartenance to a group and epidemiological factors, such as age or ethnical origin. [less ▲]

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See detailNouvelle mutation du Fibroblast Growth Factor Receptor 1 (FGFR1)-cause d'hypogonadisme hypogonadotrope idiopathique normosmique
Potorac, Iulia ULg; Chachati, Anne-Sophie ULg; Debray, François-Guillaume ULg et al

in Abstract book- Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailUne lésion sellaire d'évolution hautement fluctuante
BETEA, Daniela ULg; Potorac, Iulia ULg; BONNEVILLE, Jean-François ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailMars atmospheric escape constrained using MAVEN IUVS coronal observations
Chaffin; Deighan; Chauffray et al

Conference (2015, October)

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See detailDévelopper l'autorégulation et les compétences en résolution de problèmes : une étude exploratoire en fin d'enseignement primaire
Fagnant, Annick ULg; Jaegers, Doriane ULg

Conference (2015, October)

L’article s’appuie sur une étude exploratoire en fin d'enseignement primaire (grade 6, élèves de 11-12 ans). L’approche d’enseignement/apprentissage mise en place visait conjointement à développer des ... [more ▼]

L’article s’appuie sur une étude exploratoire en fin d'enseignement primaire (grade 6, élèves de 11-12 ans). L’approche d’enseignement/apprentissage mise en place visait conjointement à développer des capacités d’autorégulation et l’apprentissage d’une démarche de résolution de problèmes en favorisant les régulations interactives et, particulièrement, le recours à une grille de co-évaluation. Le dispositif quasi-expérimental de l’étude permet d’apprécier les progrès plus importants des élèves de la classe expérimentale (comparativement à une classe contrôle) en termes de performances mais aussi d’une certaine anticipation et planification de la démarche de résolution. Ils démontrent aussi de meilleures capacités d’autoévaluation. Les entretiens réalisés avec quelques élèves permettent de mettre en évidence la plus-value des différentes formes de régulations interactives mises en place. Enfin, plusieurs éléments permettent également d’émettre l’hypothèse d’un impact positif de l’approche sur les variables affectives et motivationnelles. [less ▲]

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See detailApparatuses as loci of bio-political emergence: development of genetic testing in Belgium
Fallon, Catherine ULg

Conference (2015, October)

In his vision of “biopolitics” Lemke (2011) proposes to conceptualize life and politics as entities intertwined within a dynamic relationship. These technologies change the production of norms and the ... [more ▼]

In his vision of “biopolitics” Lemke (2011) proposes to conceptualize life and politics as entities intertwined within a dynamic relationship. These technologies change the production of norms and the apparatuses (Foucault 2008) organizing the distribution of the living in the domain of utility: therefore biopolitics must be analyzed as center pieces in the transformation of politics. The developments in genomics and epigenetics support the vision of the individual body as an “information network” rather than a physical substrate. The experts (with the active support of the patients) construct models for the calculation of life in the development of policy regulation and contribute actively to frame the policy relevant issues – either at individual or at population level, on the basis of power strategies mobilizing and disseminating specific forms of knowledge which are disciplined and selective. The contribution will present the recent evolution of the apparatuses producing the technical regulation and financial norms for the use of genetic testing in the federal Belgian public health system, considering the two complementary level of the “dispositif” : - At the political level, transformation of the « Conseil supérieur de la Génétique humaine » (1973-2013) into a « Collège de médecins pour le centre de génétique humaine » and the development of new control relations between the subsidizing and control bodies and the hospitals, - At the individual level, transformation of the cooperation between medical doctors, biomedical experts and psycho-sociologists in the relationship with the patients, as they can be observed at the level of the hospital; Who has the resources (intellectual, technological or financial) to control the technology and its use ? what are the social, institutional and technological constrains? who defines and select the legitimate options ? The analysis is not so much normative than critical, giving due attention to the social context and contingent rationalities in the evolution of this peculiar political action, with the aim of opening new areas of discussions transgressing disciplinary and institutional borders which are too often considered as self evident. [less ▲]

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See detailL’institution de la contre-culture
Saint-Amand, Denis ULg

Conference (2015, October)

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See detailHyperparathyroïdie primaire familiale isolée - corrélation génotype - phénotype des mutations MEN 1?
Potorac, Iulia ULg; BETEA, Daniela ULg; PETROSSIANS, Patrick ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailA Generic Feature Selection Method for Background Subtraction Using Global Foreground Models
Braham, Marc ULg; Van Droogenbroeck, Marc ULg

in Advanced Concepts for Intelligent Vision Systems (2015, October)

Over the last few years, a wide variety of background subtraction algorithms have been proposed for the detection of moving objects in videos acquired with a static camera. While much effort have been ... [more ▼]

Over the last few years, a wide variety of background subtraction algorithms have been proposed for the detection of moving objects in videos acquired with a static camera. While much effort have been devoted to the development of robust background models, the automatic spatial selection of useful features for representing the background has been neglected. In this paper, we propose a generic and tractable feature selection method. Interesting contributions of this work are the proposal of a selection process coherent with the segmentation process and the exploitation of global foreground models in the selection strategy. Experiments conducted on the ViBe algorithm show that our feature selection technique improves the segmentation results. [less ▲]

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See detailPALEO-DELTA: Palaeoenvironment and geoarchaeology of the Medjerda delta (Tunisia)
Pleuger, Elisa ULg; Abichou, Hakim; Gadhoum, Ahmed et al

Poster (2015, October)

Phoenician Utica remains today largely unknown, as is its role in the Phoenician expansion in the western Mediterranean. Aristotle and Pliny the Elder mention Utica as a maritime and port city and ... [more ▼]

Phoenician Utica remains today largely unknown, as is its role in the Phoenician expansion in the western Mediterranean. Aristotle and Pliny the Elder mention Utica as a maritime and port city and estimate its origin around the 11th c. BC. However, in the present state of research, no archaeological evidence is earlier than the 9th c. BC, and the location of the Phoenician and Roman port infrastructures remains unknown. Today, the ancient city is located on a promontory in the heart of the Medjerda delta, 10 km inland. This project proposes an interdisciplinary effort to understand the Medjerda delta landscape changes during the Holocene. It starts from an archaeological problem and proposes the contribution of geoarchaeology to the understanding of the relationship between ancient societies and their environment. The fluvial palaeoenvironments and sedimentary processes are studied through the mechanical extraction of cores (15-20 m deep) to reach the early Holocene. Selected sediment samples are then studied in laboratory, using different and complementary approaches. The location of port infrastructures will bring initial answers to the question of the foundation of the city. The study of river palaeoenvironments of the Medjerda delta during the Holocene aim at a better understanding of the nature of the settlement, as well as the function of the city of Utica over time. This study will also assess the impact of the ancient city on the environment and understand how the city adapted to the mobility of this Mediterranean delta. Furthermore, the analysis of sedimentary processes causing the filling of the harbour basin will lead to speculation about the causes of the abandonment of the structures and more generally the decline of the city in favor of Carthage. It will also examine whether natural or anthropogenic factors have influenced this deltaic progradation over the centuries. [less ▲]

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See detailIrrigation Development Support Program - Agricultural water management in Burkina Faso
Traoré, Farid; Wellens, Joost ULg; Tychon, Bernard ULg et al

Poster (2015, October)

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See detailLa vulnerabilidad como valor jurídico-ético para asegurar el «best interest» de los menores: comparación entre el tribunal europeo de derechos humanos y el tribunal de justicia de la Unión Europea
Colussi, Ilaria Anna ULg

in Alvarez Vélez, Isabel; Rey Pérez, José Louis (Eds.) Derecho y pobreza (2015, October)

Within the concept of "vulnerability" - considered as an inherent or innate value of the human being, from which it is necessary to start in order to build a genuine social policy- the children's ... [more ▼]

Within the concept of "vulnerability" - considered as an inherent or innate value of the human being, from which it is necessary to start in order to build a genuine social policy- the children's vulnerability occupies a special position. Traditionally, children have been treated as objects of protection and not as subjects of rights according to an authoritarian and paternalistic perspective. Over time, a different view of this matter has developed, and it has put the child at the center of attention, considering his vulnerabilities, needs and interests. This perspective has been reflected in the legislation, in case law and doctrine, both internationally and nationally. The concept of "best interest" is the key for addressing children's vulnerability of children and developing substantive equality for them. The European Court of Human Rights in Strasbourg and the Court of Justice of the European Union in Luxembourg have defined this concept in different areas: in the field of international child abduction, immigration, asylum and family reunification, custody and parental responsibility. Although these two tribunals have grounded their arguments on different legal perspectives, both have shown and still show a trend towards convergence to common points, through a balanced consideration of rights in this area. This communication aims at examining the relevant jurisprudence of the aforementioned tribunals about the notion of "best interest" of the child. The case-law since 2011 until 2015 has been taken into account. [less ▲]

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See detailUse of a HCV patients' education tool: the knowledge questionnaire with confidence degrees
Kerrad, Amel; Leclercq, Dieudonné ULg; Barreteau, H. et al

Poster (2015, October)

13 patiuent ssuffering of C hepatis have received a pretest on knowledge with confidence degrees accompanying their responses. On the basis of thes responses, they received individual education by a ... [more ▼]

13 patiuent ssuffering of C hepatis have received a pretest on knowledge with confidence degrees accompanying their responses. On the basis of thes responses, they received individual education by a pharmacist about their treatment. A post-test, again with confidence degrees, permitted to measure, according to methods described by Leclercq (2009), to evidence objective and subjective gains in knowledge as well in patients' adherence to treatment. [less ▲]

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See detailFungal biofilm reactor improves the quality of a fusion protein GLA::GFP produced by Aspergillus oryzae
Zune, Quentin ULg; Delepierre, Anissa ULg; Bauwens, Julien ULg et al

Poster (2015, October)

Fungal biofilm is known to promote the excretion of secondary metabolites, in accordance with solid-state related physiological mechanisms. In this work, the potentialities of fungal biofilm will be ... [more ▼]

Fungal biofilm is known to promote the excretion of secondary metabolites, in accordance with solid-state related physiological mechanisms. In this work, the potentialities of fungal biofilm will be investigated in the context of the production of a Gla::GFP fusion protein by Aspergillus oryzae. Since the production of this protein is under the control of the promoter glaB, specifically induced in solid-state fermentation, biofilm mode of culture is expected to enhance the global productivity. However, we found that the glaB promoter is also activated in submerged bioreactor and the fusion protein production is higher in this mode of culture. This result is related to the high shear stress leading to biomass autolysis and leakage of intracellular fusion protein into the extracellular medium. Moreover, 2D-gel electrophoresis highlights preservation of the fusion protein integrity produced in biofilm conditions whereas proteolysis strongly affects fusion protein recovery in the submerged cultures performed at high stirring rate. Fungal biofilm reactor design was then further investigated and the scale-up potentialities were evaluated. Indeed, the specific design investigated in this work involves the use of metal structured packing exhibiting a high specific area and that can be easily expanded to large-scale bioprocessing conditions. [less ▲]

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See detailCanine idopathic pulmonary fibrosis is not associated with herpes virus infection
Roels, Elodie ULg; Dourcy, Mickael ULg; Holopainen, S. et al

Poster (2015, October)

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See detailImplication of adamalysin proteases in mesothelioma
Sepult, Christelle ULg; Rocks, Natacha ULg; Bekaert, Sandrine et al

Conference (2015, September 30)

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See detailL'enseignement-apprentissage du néerlandais en Fédération Wallonie-Bruxelles: objectifs, méthodes, résultats
Rasier, Laurent ULg; Hiligsmann, Philippe

Conference (2015, September 30)

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See detailPasser à Alma d’Ex Libris : projet de réinformatisation ? projet de bibliothèque ? L'expérience de l'Université de Liège 6 mois avant et 6 mois après
Renaville, François ULg; Thirion, Paul ULg

Conference (2015, September 29)

En janvier 2014, les Bibliothèques de l'Université de Liège ont décidé de passer au système de gestion de bibliothèque Alma. Le projet a débuté en août 2014 ; six mois après, la migration vers Alma et le ... [more ▼]

En janvier 2014, les Bibliothèques de l'Université de Liège ont décidé de passer au système de gestion de bibliothèque Alma. Le projet a débuté en août 2014 ; six mois après, la migration vers Alma et le lancement d'une nouvelle interface de découverte Primo étaient réalisés. Cette présentation balaye les moments clés de ce projet, en mettant l'accent sur la composante organisationnelle et la gestion du changement, ainsi que sur les premiers mois d’expérience avec le nouvel outil. [less ▲]

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See detailSimulations of the auroral signatures of Jupiter’s magnetospheric injections
Dumont, Maïté ULg; Grodent, Denis ULg; Radioti, Aikaterini ULg et al

Conference (2015, September 29)

We report the evolution of ultraviolet auroral features located equatorward of the main emission appearing in the Hubble Space Telescope (HST) images of the northern and the southern Jovian hemisphere. We ... [more ▼]

We report the evolution of ultraviolet auroral features located equatorward of the main emission appearing in the Hubble Space Telescope (HST) images of the northern and the southern Jovian hemisphere. We investigate the possibility that those ultraviolet auroral structures are associated with energetic particle injections. For this study, we compare the characteristics of the simulated auroral signature of plasma injections with the observed parameters of equatorward isolated auroral structures. [less ▲]

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See detailBien soigner l'arthrose: un enjeu capital pour notre société!
Henrotin, Yves ULg

Conference (2015, September 29)

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See detailBetter tests better care : Syndrome-based diagnostics for respiratory tract infections
MELIN, Pierrette ULg

Conference (2015, September 29)

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See detailTrace metal speciation? An essential aspect of biomonitoring to avoid wrong conclusions
Richir, Jonathan ULg; Lepoint, Gilles ULg; Donnay, Annick et al

Poster (2015, September 29)

The Mediterranean mussel Mytilus galloprovincialis is widely used as a bioindicator species in active monitoring surveys. As a filter feeder artificially maintained in the water column, it bioaccumulates ... [more ▼]

The Mediterranean mussel Mytilus galloprovincialis is widely used as a bioindicator species in active monitoring surveys. As a filter feeder artificially maintained in the water column, it bioaccumulates trace metals from the surrounding water in their dissolved and particulate forms. However, most monitoring surveys don’t take into account that speciation aspect when studying trace metal accumulation kinetics in mussels. In the framework of the STARECAPMED project, we monitored trace metal concentrations in the flesh of mussels together with their “most bioavailable” dissolved and particulate fractions in the water column for almost 5 months (February-June 2011). Mussels were purchased from 2 little contaminated French shellfish farms (SARL Etang de Diane and ferme marine des Aresquiers), placed in several pouches to allow regular sampling, and immerged near the Oceanographic Research Station STARESO in the Calvi bay, northwestern Corsica. Mussels and water samples for suspended matter filtration were collected every week to two weeks, as were deployed DGTs. Seawater samples were filtered through 47 mm hydrophilic PTFE membrane filters with a 0.45 µm pore size until clogging. In the laboratory, mussel flesh and filters were digested in Teflon vessels with acids (HNO3/H202) in a closed microwave digestion lab station. DGT resins were eluted for 24h in 1.0 M HNO3. Trace metal concentrations (Cr, Mn, Co, Ni, Cu, Zn, Ag, Cd, Pb) were measured by DRC-ICP-MS. Analytical accuracy was checked by analyzing CRMs. All the studied metals except Pb and Zn were present in the water column to over 80% in their dissolved form. The contribution of the dissolved pathway was thus likely to be predominant in the oligotrophic Calvi bay. Dissolved trace metals showed little temporal variability of their levels, likely resulting from the integration over time of their levels in the DGT probes and the lack of seasonality of this fraction. In contrast, Zn showed great variability of its particulate fraction during the survey. Such temporal variability was also observed for Cr, more abundant in its particulate form at the end of the survey, and for Mn and Pb that conversely tended to decrease. The dynamic of trace metals in the mussel flesh is regulated by the environmental bioavailability of dissolved and particulate metals, the ecophysiological status of mussels and the trophic conditions of the water body. In the oligotrophic Calvi bay, showing background contamination levels by metals, the trophic conditions played a major role once out of the spring plankton bloom. It led to the increase of metal concentrations measured in the flesh of mussels undergoing starvation. However, some metals such as Cu and Co displayed only little temporal variations of their concentrations, these essential micronutrients being well regulated. The combined study of trace metal bioavailability and mussel ecophysiology in defined environmental conditions allows discriminating against biotic and abiotic factors regulating contaminant uptake in mussels, thus avoiding wrong conclusions about the observed dynamics of the studied contaminants. Mussels are a good proxy of coastal water quality, but their proper use notably requires adjustment of raw contaminant concentrations with trophic status of monitored sites. [less ▲]

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See detailStatistical analysis and multi-instrument overview of the quasi-periodic 1-hour pulsations in the Saturn's outer magnetosphere
Palmaerts, Benjamin ULg; Roussos, Elias; Krupp, Norbert et al

Poster (2015, September 29)

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See detailExperimental and in silico approaches to study the interaction of Remorin with plant plasma membrane : specific interaction of the C-term domain with lipids
Deleu, Magali ULg; Nasir, Mehmet Nail ULg; Gronnier, Julien et al

Conference (2015, September 29)

The function of Remorins, a diverse family of plant-specific proteins (1) is far to be fully elucidated. One of them, StREM1.3 (for Solanum tuberosum Remorin from group 1, homolog 3) has been reported to ... [more ▼]

The function of Remorins, a diverse family of plant-specific proteins (1) is far to be fully elucidated. One of them, StREM1.3 (for Solanum tuberosum Remorin from group 1, homolog 3) has been reported to regulate cell-to-cell propagation of the potato virus X (2). It was also shown to be localized to the inner leaflet of plasma membranes (PMs) and along plasmodesmata, bridges connecting neighbor cells essential for cell-to-cell communication in plants (3). The mechanisms driving StREM1.3 association with PM is still an open question. It was shown recently that a domain of 28 residues at the C-terminus of the potato (RemCA) is required and sufficient for anchoring to the PM (4). Here we combined experimental and in silico biophysics to unravel the molecular bases of RemCA membrane binding. Biomimetic membrane models of plant PM such as monolayers and liposomes were used with various biophysical techniques (Langmuir monolayer technique, Fourier-transformed infrared spectroscopy, circular dichroïsm) and modeling tools (home-made methods and molecular dynamics) (5) to answer to three questions: (i) What is the conformation adopted by RemCA within a membrane?, (ii) Is there any membrane lipid specificity in the RemCA-membrane binding? (iii) What is the role of the two different RemCA domains in the interaction? Results show that RemCA displays a preference for plant phosphoinositide and sitosterol-enriched inner leaflet plasma membrane rafts. Within the membrane, the C-terminal and the N-terminal domains adopt a random coil and a -helical conformation respectively. The C-terminal domain acts as a driver to bind RemCA to the membrane while the N-terminal domain stabilizes the peptide at the membrane. Lysine residues have a crucial importance in this interaction. References (1) Raffaele et al., Plant Physiol., 2007, 145: 593–600 (2) Raffaela et al., Plant Cell, 2009, 21: 1541–1555. (3) Maule, Curr. Opin. Plant Biol., 2008, 11: 680–686. (4) Perraki et al., Plant Physiology, 2012, 160 : 624-637. (5) Deleu et al., Biochim. Biophys. Acta – Biomembranes, 2014, 1838 : 3171-3190. [less ▲]

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See detailDynamics of the active region in Jupiter’s aurorae
Bonfond, Bertrand ULg; Grodent, Denis ULg; Badman, Sarah et al

Conference (2015, September 29)

The Far-UV aurorae at Jupiter variety on a wide range of timescales. This study focuses on the dynamics of the active region on timescales of a few minutes. Up to now, only the time-tag mode of the Space ... [more ▼]

The Far-UV aurorae at Jupiter variety on a wide range of timescales. This study focuses on the dynamics of the active region on timescales of a few minutes. Up to now, only the time-tag mode of the Space Telescope Imaging Spectrograph provides access to such fast variations with a high spatial resolution. This active region, located on the dusk flank of the area inside the main auroral oval, is the locus of particularly bright (up to several mega Reyleighs) and sudden (a few tens of seconds) enhancements called flares. A previous study also showed that these flare could reoccur quasi-periodically every 2-3 minutes and propagate from dusk to dawn. Here we use data obtained in 2013 and 2014 to show that this quasi-periodic behavior is only present on half of the cases and that the affected region could either cover the whole active region or a much smaller area (∼5000km^2). We also found areas that were still during part of the observation sequence and then began to blink (see Figure 1). We also show that there no systematically preferred propagation direction. Finally, sequences acquired successively in the two hemispheres show that the quasi-periodic flares can be in phase [less ▲]

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See detailLe projet expérimental multidisciplinaire (PEMD) en 3ème Bachelier à Gembloux
Colaux-Castillo, Catherine; Pochet, Bernard ULg

in Former aux compétences informationnelles à l'heure du web 2.0 et des discovery tools (2015, September 28)

Cette courte présentation, dans l'atelier 3 du colloque ILIB15, décrit l'intégration d'un cours (« littérature scientifique et méthodologie documentaire »), dont le titulaire est un bibliothécaire, dans ... [more ▼]

Cette courte présentation, dans l'atelier 3 du colloque ILIB15, décrit l'intégration d'un cours (« littérature scientifique et méthodologie documentaire »), dont le titulaire est un bibliothécaire, dans une unité d’apprentissage intégrée basée sur la résolution d'un problème concret de recherche dans un contexte scientifique non familier. Ce cours a été proposé pour la première fois durant l'année académique 2014-2015 à une partie des étudiants du bloc trois du Master Bioingénieur, orientation Sciences et technologies de l’environnement de l'Université de Liège. Cette activité se déroule en plusieurs phases sur les deux quadrimestres. [less ▲]

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See detailMilk production, milking frequency and rumination time of grazing dairy cows milked by a mobile milking robot.
Lessire, Françoise ULg; Hornick, Jean-Luc ULg; Minet, Julien ULg et al

in Conington, J; Klopcic, M; Lauridsen, C (Eds.) et al Book of abstracts of the 66th Annual meeting of the European Federation of animal science (2015, September 28)

In Europe, analysis of meteorological data shows that the average temperature has increased by ~1°C over the past hundred years (IPCC, 2013). Heat stress periods are thus expected to be more frequent even ... [more ▼]

In Europe, analysis of meteorological data shows that the average temperature has increased by ~1°C over the past hundred years (IPCC, 2013). Heat stress periods are thus expected to be more frequent even in temperate areas. The use of an automatic milking system (AMS) implies the need to stimulate cows’ traffic to the robot, especially with grazing cows. Describing how heat stress influenced cows’ traffic to the robot is the aim of this study. Grazing dairy cows milked by an automatic system (AMS) experienced heat stress (HS) periods, twice during the summer 2013 in July (J) and August (A). The daily temperature humidity index (THI) during these periods were higher than 75. Each HS period was compared with a “normal period”(N), presenting the same number of cows, similar lactation number, days in milk, distance to come back to the robot and an equal access to water. The first HS period of 5 days with a mean THI of 78.4 was chosen in J, and a second that lasted for 6 days in A with a THI value of 77.3. Heat stress periods were cut off with the same duration of days with no stress (N) and mean THI <70. Milk production, milkings and refusals to the robot during HS were compared with N periods. Milkings and refusals were significantly more numerous in HS periods in July (HS: 2.54 ± 0.11 vs N: 2.19 ± 0.08, 1.87 ± 0.20 vs 0.72 ± 0.16) but milk production dropped from 21.8 ±0.6 kg per cow and per day during N periods to 18.9 ± 0.8 kg in HS. In August, MY increased slightly during HS. This could be explained by less high ambient temperatures and decreased distance to walk inducing less energy expenditure. The increase in milkings and refusals to the robot during HS could be linked to water availability nearby the robot and confirmed previous findings (Lessire et al., 2014). [less ▲]

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See detailHigh-throughput sequencing of toxins with pharmacological interest: proof of concept and first applications
Echterbille, Julien ULg; Degueldre, Michel ULg; Boulanger, Madeleine ULg et al

Conference (2015, September 28)

Animal venoms are complex chemical cocktails, comprising wide ranges of biologically active reticulated peptides that target with high selectivity and efficacy varieties of membrane receptors. Assuming ... [more ▼]

Animal venoms are complex chemical cocktails, comprising wide ranges of biologically active reticulated peptides that target with high selectivity and efficacy varieties of membrane receptors. Assuming the fact that each of the 170,000 venomous species reported can produce more than 250 bioactive toxins, at least 40,000,000 bioactive peptides and proteins may be discovered. Among the four described species of mambas, Eastern Jameson’s mamba (Dendroaspis jamesonii kaimosae) venom is the less characterized since only 9 peptides are referenced in database. This work aims at developing a new strategy devoted to the deep analysis of animal venoms. Our approach consists in a first separation of the venom using cation exchange chromatography. Each primary fraction is then purified a second time by classical RP-HPLC. A total of 328 fractions, containing amongst 1 and 4 toxins, are finally collected. MALDI-MS analysis of each fraction is done in order (1) to obtain information about masses and (2) to obtain sequences of toxins thanks to MALDI-In Source Decay (ISD) dissociation coupled with on MALDI target plate reduction of the peptides. ISD has already been demonstrated efficient for toxin sequencing1, and especially when using 1,5-DAN as reducing matrix2. ISD yields to sequences that cover more than 50% of peptide sequences by series of singly charged c-type ions. Thanks to this methodology, we were able to obtain 85% of satisfactory results i.e. spectra giving quite long tags of amino acids (up to 20 residues). As a way to validate our method, a tag coming from ISD spectrum interpretation has found a match in database for an Eastern Jameson’s mamba toxin. The global sequence has then been obtained by extrapolation on the ISD spectrum. Since ISD spectra are simpler than classical MS/MS spectra, automation of spectra interpretation, difficult with other fragmentation techniques (CID, ETD…), is implementable. In the near future, sequences obtained with this approach will be used to direct tests of biological activity through sequence homologies with already known ligands for different kinds of membrane receptors. [less ▲]

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See detailAnalysis of the retaining wall design problem in the framework of the Tyler Rationale
Charlier, Robert ULg; Bertrand, François ULg; Cerfontaine, Benjamin ULg et al

Poster (2015, September 28)

The coherence of any education system lies on the respect of the Tyler Rationale which puts the relationship between the objectives, the teaching method and the evaluation forward. The practical part of ... [more ▼]

The coherence of any education system lies on the respect of the Tyler Rationale which puts the relationship between the objectives, the teaching method and the evaluation forward. The practical part of the examination of the course of Geotechnics generally includes a retaining wall design problem. We listed and classified the mistakes identified in the student answers for the retaining wall design problem. In this classification, the mistakes specific to geotechnics are distinguished from the ones which are not specific to geotechnics. This list allows the teacher to be aware of the most common mistakes so he can insist on things not to do during the learning experiences. The classification is also fundamental. Indeed, if a student failed essentially because of a lack of pre-requisites, there is no reason he succeed by repeating the course in the same conditions. He should be therefore redirected to a self-regulating. [less ▲]

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See detailPsychological benefits of a multidisciplinary rehabilitation program after breast cancer
Leclerc, Anne-France ULg; FOIDART-DESSALLE, Marguerite ULg; Bury, Thierry ULg et al

Conference (2015, September 27)

Background : Breast cancer is the most frequent cancer in women, affecting 8 women out of 100. With early detection and improved treatments, the number of deaths linked to this disease has declined ... [more ▼]

Background : Breast cancer is the most frequent cancer in women, affecting 8 women out of 100. With early detection and improved treatments, the number of deaths linked to this disease has declined. However, the disease and its treatments are at the origin of many undesirable side effects such as fatigue, anxiety, weight gain and sleep disorders. The objective of this study is to determine the psychological benefits of a multidisciplinary rehabilitation program among women treated for breast cancer (on average six months after the end of the adjuvant radiotherapy or chimiotherapy). Material and methods : 122 patients were included into a control group (n = 61) and a treated group (n = 61). All participants were submitted to evaluations before the beginning of the trial and after three months. These evaluations included different questionnaires exploring the quality of life, anxiety, depression and various functions and other symptoms related to cancer (EORTC QLQ-C30, EQ-5D, STAI, HADS) and functional assessments. The control group has received no intervention unlike the treated group that received a three-month rehabilitation including supervised physical training (90 min) with three times a week and various psycho-educational sessions (120 min) once a week. Results : After three months, the health status (quality of life) (p < 0,0001), the functional role (p = 0,031), emotional state (p < 0,0001) and physical (p = 0,0045), cognitive (p = 0,0027) and social functions (p = 0,0018) improve significantly in the treated group. This observation also applies to symptoms of fatigue (p < 0,0001), insomnia (p < 0,0001), pain (p = 0,002), dyspnea (p = 0,009), loss of appetite (p = 0,04), anxiety (p < 0,0001) and depression (p < 0,0001) as well as physical parameters obtained through functional assessments. In the control group, these improvements do not appear. Conclusions : This study shows the feasibility and psychological benefits of such a multidisciplinary oncological rehabilitation program in women after their treatments for breast cancer. Additional studies are needed to know the optimal time of beginning (during treatments or after them) and the optimal management time for this support. [less ▲]

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See detailPhysical benefits of a multidisciplinary rehabilitation program after breast cancer
Leclerc, Anne-France ULg; FOIDART-DESSALLE, Marguerite ULg; Bury, Thierry ULg et al

Poster (2015, September 26)

Background : Breast cancer is the most frequent cancer in women, affecting 8 women out of 100. With early detection and improved treatments, the number of deaths linked to this disease has declined ... [more ▼]

Background : Breast cancer is the most frequent cancer in women, affecting 8 women out of 100. With early detection and improved treatments, the number of deaths linked to this disease has declined. However, the disease and its treatments are at the origin of many undesirable side effects such as fatigue, anxiety, weight gain and decreased physical fitness. The objective of this study is to determine the physical benefits of a multidisciplinary rehabilitation program among women treated for breast cancer (on average six months after the end of the adjuvant radiotherapy or chimiotherapy). Material and methods : 122 patients were included into a control group (n = 61) and a treated group (n = 61). All participants were submitted to evaluations before the beginning of the trial and after three months. These evaluations included functional assessments (a maximal incremental exercise protocol on a cycle ergometer, flexibility by Sit and Reach Test and walking distance by Six-Minute Walk Test), anthropometric and body composition measurements (Body Mass Index and body fat percentage) and different questionnaires on quality of life, anxiety and other symptoms related to cancer. The control group has received no intervention unlike the treated group that received a three-month rehabilitation including supervised physical training (90 min) with three times a week and various psycho-educational sessions (120 min) once a week. Results : After three months, maximal oxygen consumption (p < 0,0001), maximal aerobic power (p < 0,0001), peak of ventilation (p < 0,0001) and time to exhaustion (p = 0,0055) during the maximal incremental exercise protocol improve significantly in the treated group. This observation also applies to flexibility (p < 0,0001), walking distance in six minutes (p < 0,0001) and different physical and psychological parameters obtained through questionnaires. In the control group, these improvements do not appear and a significant increase in body mass index (p = 0,032) and body fat percentage (p = 0,034) is observed while these data remain constant in the treated group. Conclusions : This study shows the feasibility and physical benefits of such a multidisciplinary oncological rehabilitation program in women after their treatments for breast cancer. Additional studies are needed to know the optimal time of beginning (during treatments or after them) and the optimal management time for this support. [less ▲]

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See detailHypoxic ischemic encephalopathy : new insights in neuroprotection
VIELLEVOYE, Renaud ULg

Conference (2015, September 26)

Hypoxic-ischemic encephalopathy (HIE) is a major contributor to neonatal morbidity and mortality and is a common cause of disability with devastating impact on individuals and families. During the acute ... [more ▼]

Hypoxic-ischemic encephalopathy (HIE) is a major contributor to neonatal morbidity and mortality and is a common cause of disability with devastating impact on individuals and families. During the acute phase, HIE is initially characterized by an excitotoxic cascade with hypoxic membrane depolarization, cytotoxic edema, glutamate release and intracellular accumulation of calcium leading to necrotic cell death and production of proinflammatory cytokines through the NF-κB pathway. In a second phase, reperfusion leads to production of free radicals, activation of proteases and phospholipases, exacerbing the damage to cell membrane and DNA and mitochondrial dysfunction causing caspase mediated apoptotic cell death. In a third phase, growth factors and inflammatory cytokines produced during the early phase of HIE attempt to repair damage induced by hypoxia–ischemia. Although the utility of therapeutic hypothermia induced in the 6 hours following HIE in the reduction of death or major neurodevelopmental disability is now well established in the neonate with moderate or severe encephalopathy, almost half of these children still die or have abnormal outcomes [1]. Protocols attempting to optimize cooling with deeper hypothermia (33.5°C vs 32.0°C) and/or longer duration (72h vs 120h), as well protocols studying neuroprotective effect of late hypothermia (6-24h) or hypothermia for 33-35 week GA preterm babies are currently performed. Furthermore, experimental data suggest that hypothermia extends the duration of the therapeutic window [2] and that certain drugs given during this time may improve neuroprotection either additively or synergistically. Xenon is a noble gas with anaesthetic and neuroprotective properties. It inhibits NMDA receptor, promotes cell survival and induces the production of erythropoietin and vascular endothelial growth factor through the hypoxia inducible factor 1 alpha (HIF-1α) pathway. Data from experimental piglet models of hypoxia-ischemia (HI) demonstrate a synergy when Xenon is administered in combination with mild therapeutic hypothermia [3]. In the human newborn, a phase-1 trial recently established that breathing 50% Xenon for up to 18 hours with 72 hours of cooling was feasible, with no adverse effects seen with 18 months’ follow-up [4]. A monocentric phase-3 trial is currently under process in England. Melatonin is a remarkable natural antioxidant but also exhibits antiapoptotic and anti-inflammatory properties in vitro. In animal models, melatonin administration prior or after the onset of HI significantly reduced infarct volume demonstrating both prophylactic and therapeutic effect [5-6]. When combined with hypothermia, melatonin enhances neuroprotection by reduction of the H–I-induced increase in clinically relevant biomarkers in the deep grey matter of newborn piglets [7]. Clinical studies confirmed its safety profile and its ability to reduce biomarkers level of HI in the human newborn [8]. Recently, a randomized controlled trial showed that the combination of melatonin and hypothermia administered to infants with moderate-to-severe H–I brain injury was efficacious in reducing oxidative stress, neonatal seizures and MRI brain lesions as well as in improving neurological outcomes at 6 months of age [9]. Erythropoietin (EPO) and its receptor are expressed in the developing central nervous system and are required for normal brain development. EPO is up-regulated in umbilical cord blood from babies who have suffered HI, which may be an endogenous repair mechanism. In vitro and in vivo neuroprotection induced by EPO is achieved by several mechanisms such as direct neurotrophic effect, direct antioxidant effects, decreased inflammation or regulation between pro-apoptotic and anti-apoptotic factors. Safety profile of EPO administration during hypothermia for newborns with HIE has been established in Phase I trials [10]. In a randomized prospective pase-2 trial, repeated low-dose rEPO reduced the risk of disability for infants with moderate but not severe HIE at 18 months, without apparent side effects [11]. A double-blind randomized controlled phase-3 trial is currently performed in France. Allopurinol is a xantine-oxidase inhibitor. In high concentrations it also scavenges hydroxyl radicals and prevents free radical formation. Allopurinol provides neuroprotection in rat and piglets models of HIE. In the human, a systematic review and meta-analysis of three studies on 114 newborns did not reveal statistically difference in the risk of death or a composite of death or severe neurodevelopmental disability between groups [12]. It was hypothesized that postnatal allopurinol treatment started too late to reduce reperfusion-induced free radical surge. However, in a recent study, allopurinol given to mothers during labor with fetal hypoxia did not significantly lower neuronal damage markers in cord blood even if post hoc analysis revealed a potential beneficial treatment effect in girls [13]. Magnesium sulfate (MgSO4) is a naturally occurring NMDA receptor antagonist. MgSO4 given to mothers at risk for preterm birth is associated with a reduced risk of cerebral palsy and gross motor dysfunction in their children. Its role as an adjuvant to therapeutic hypothermia in the asphyxiated term infant remains unclear. A recent review of preclinical studies using MgSO4 in HIE highlights the inconsistent impact between studies related to a lack of temperature control during and after HI, along with variability in the dose, timing of treatment [14]. A metaanalysis of five randomized controlled trials that compared magnesium to control in newborns with HIE showed a significant improvement in short term outcomes but no difference in the composite outcome of death or moderate to severe disability at 18 months [15]. Other NMDA and AMPA antagonist such as topiramate and memantine also exhibited neuroprotective properties in animal models but safety and efficacy in the human newborn with HIE still needs to be clarified [16]. N-acetyl cysteine (NAC) acts as a glutathione precursor with antioxidant, antiapoptotic, and anti-inflammatory properties. In a piglet model of HIE, NAC reduced cerebral oxidative stress, reduced cerebral lactate accumulation and improved cerebral perfusion. When combined with hypothermia in the asphyxiated rodent, NAC decreased infarct volume, improved myelin expression and functional outcomes on a synergistic pattern. NF-κB inhibitors and NO synthase inhibitors are other therapeutic options currently under investigation in in vitro and in vivo preclinical studies. Moreover, recent research performed at the University of Liege also suggests that Estetrol (E4), an estrogen synthetized exclusively by the human foetus, has neuroprotective properties in a rat model of HIE. Translation to clinical use in humans still needs to be studied [17]. Several therapies have also been suggested in order to improve mechanisms of repair and regeneration observed after the HI insult. Growth factors such as BDNF, IGF-1, EGF or bFGF can improve cell viability, stimulate the growth of new neurons or promotes oligodendroglial differentiation and myelination. Recent advances in regenerative medicine suggest that stem cell transplantation may improve repair of the damaged brain after HIE through the replacement of dead cells as well as through the release of trophic factors [18]. Animal preclinical data are promising. However many questions need to be answered with well-designed controlled trials before clinical application in daily practice. References [1] Edwards AD et al. (2010) Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data. BMJ. 340:c363. [2] O'Brien F et al. (2006) Delayed whole-body cooling to 33 or 35 degrees c and the development of impaired energy generation consequential to transient cerebral hypoxia-ischemia in the newborn piglet. Pediatrics 117:1549–59. [3] Chakkarapani, E. et al. (2010) Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs. Ann. Neurol. 68, 330–341 [4] Dingley, J. et al. (2014) Xenon ventilation during therapeutic hypothermia in neonatal encephalopathy: a feasibility study. Pediatrics 133, 809–818 [5] Carloni, S. et al. (2008) Melatonin protects from the long-term consequences of a neonatal hypoxic–ischemic brain injury in rats. J. Pineal. Res. 44, 157–164 [6] Hutton, L.C. et al. (2009) Neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (Acomyscahirinus). Dev. Neurosci. 31, 437–451 [7] Robertson, N.J. et al. (2013) Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model. Brain 136, 90–105 [8] Fulia, G. et al. (2001) Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin. Journal of Pineal Research; 31(4):343–349. [9] Aly, H. et al. (2015) Melatonin use for neuroprotection in perinatal asphyxia: a randomized controlled pilot study. J. Perinatol. 35, 186–191 [10] Wu, Y.W. et al. (2012) Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics. Pediatrics 130, 683–691 [11] Zhu, C. et al. (2009) Erythropoietin improved neurologic outcomes in newborns with hypoxic–ischemic encephalopathy. Pediatrics 124, 218–226 [12] Chaudhari, T. and McGuire, W. (2012) Allopurinol for preventing mortality and morbidity in newborn infants with hypoxic–ischaemic encephalopathy. Cochrane Database Syst. Rev. 7, Cd006817 [13] Kaandorp, J.J. et al. (2015) Maternal allopurinol administration during suspected fetal hypoxia: a novel neuroprotective intervention? A multicentre randomised placebo controlled trial. Arch. Dis. Child Fetal Neonatal Ed. 100, F216–F223 [14] Galinsky, R. et al. (2014) Magnesium is not consistently neuroprotective for perinatal hypoxia-ischemia in term-equivalent models in preclinical studies: a systematic review. Dev. Neurosci. 36, 73–82 [15] Tagin, M. et al. (2013) Magnesium for newborns with hypoxic–ischemic encephalopathy: a systematic review and meta-analysis. J. Perinatol. 33, 663–669 [16] Wu, Q et al. (2015) Neuroprotective agents for neonatal hypoxic–ischemic brain injury. Drug Discovery Today. [17] Tskitishvili, E et al. (2014). Estetrol attenuates neonatal hypoxic–ischemic brain injury. Experimental Neurology, 261, 298-307. [18] Kelen, D and Robertson, NJ. (2010) Experimental treatments for hypoxic ischaemic encephalopathy. Early Human Development 86; 369–377. [less ▲]

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See detailHabitants des petites villes et des villages face à la nature dans les paysages ordinaires
Vanderheyden, Vincent ULg

Conference (2015, September 25)

La recherche sur les perceptions paysagères dénigre souvent les paysages ordinaires, ces paysages modifiés par l’homme qui n’appellent pas à la protection. Pourtant, dans les régions de forte densité de ... [more ▼]

La recherche sur les perceptions paysagères dénigre souvent les paysages ordinaires, ces paysages modifiés par l’homme qui n’appellent pas à la protection. Pourtant, dans les régions de forte densité de population comme la Belgique, les paysages naturels sont rares ou inexistants, sans pour autant que la nature ait disparu des paysages ordinaires. Il est donc intéressant de se poser la question de la nature dans de tels paysages : à partir de quand un paysage est-il perçu comme naturel par ceux qui l’observent ou y vivent ? Les critères dépendent-ils du mode d’habiter (petite ville, village périurbain ou village rural) ou d’autres facteurs liés à la trajectoire biographique des gens ? Trois terrains d’études ont été retenus pour la recherche : la Wallonie picarde, l’Entre-Sambre et Meuse et l’Ardenne. Ces terrains offrent des paysages ruraux assez typés et suffisamment différenciés et éloignés des grandes agglomérations urbaines, hormis Tournai, ville d’envergure régionale. La Wallonie picarde présente des paysages de vastes plateaux agricoles limoneux au relief plan et peu élevé, occasionnellement surplombé de petites collines. L’Entre-Sambre-et-Meuse offre des paysages mixtes, alternant cultures, prairies et boisement dans un relief plus accidenté d’altitude moyenne. Enfin, l’Ardenne, troisième terrain, montre des paysages de hauts plateaux disséqués, dominés par les massifs forestiers et les pâturages. Ces terrains offrent un bel aperçu du continuum urbain-rural belge : de la petite ville en milieu rural au semis d’habitat très lâche du village ardennais, loin de l’habituelle dichotomie ville - campagne. Dans ces terrains, une approche empirique a été privilégiée. Nous y avons interviewé trois groupes de neuf étudiants (18-25 ans) d’un niveau d’éducation moyen (Bac +1 à Bac +3), non spécialistes en analyse du paysage, habitant dans de petites villes ou villages et un de leurs parents. Durant l’enquête, les personnes devaient classer des photos de paysages ruraux belges plus ou moins impactés par la présence de l’homme (habitat, cultures, éoliennes, pylônes, zones périurbaines) puis devaient motiver leur classement. Les entretiens ont été enregistrés, retranscrits et codés à l’aide d’un logiciel d’analyse qualitative. L’analyse de contenu montre des résultats contrastés. Un certain consensus indépendant du mode d’habiter semble se dégager concernant la présence d’éléments anthropiques récents, tels quel les éoliennes, les zones industrielles ou les pylônes électriques : cela participe à la dénaturation d’un paysage, avec une subtile nuance pour les éoliennes, où la symbolique positive écologique peut pour certains contrebalancer la perte de naturalité induite. Chez des personnes vivant dans un milieu plus urbanisé, le paysage naturel attire, car il change des habitudes de vie. Certains n’hésitent pas à qualifier un paysage de naturel pour peu qu’il contienne suffisamment de végétation, fusse une vaste étendue agricole dédiée à la monoculture. Chez des personnes vivant dans des milieux très ruraux par contre, on ne constate pas toujours la tendance inverse : même la petite ville voisine semble parfois trop urbanisée à leurs yeux pour y vivre. A leurs yeux, les paysages deviennent moins attractifs au fur et à mesure que la densité du bâti devient perceptible. Plus qu’une analyse du visuel, cette recherche montre également que les gens s’imaginent être dans le paysage, entendant les bruits ou ressentant une perte de convivialité à mesure que le paysage s’industrialise ou se remplit de maisons. [less ▲]

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See detailPhysicochimie de la pollution atmosphérique
Mahieu, Emmanuel ULg

Conference (2015, September 25)

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See detailEn tous quartiers ou j’ay esté. Le récit de pèlerinage de Georges Lengherand, mayeur de Mons (1486–1487)
Bruwier, Marie-Cécile; Docquier, Gilles; Marchandisse, Alain ULg

Conference (2015, September 25)

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See detailTools for Measuring a City’s Resilience in a Fire Following Earthquake Scenario
Elhami Khorasani, Negar; Gernay, Thomas ULg; Garlock, Maria

in Proceedings of IABSE Conference - Structural Engineering: Providing Solutions to Global Challenges (2015, September 25)

The paper provides a framework to evaluate the response of buildings in a community subject to fire following earthquake. First, a model is developed to determine the probability of ignition in buildings ... [more ▼]

The paper provides a framework to evaluate the response of buildings in a community subject to fire following earthquake. First, a model is developed to determine the probability of ignition in buildings of a community due to an earthquake. Second, fragility functions are developed for buildings subject to fire, to quantify the structural damage and the expected losses. The ignition model, combined with the fragility functions, can be implemented in a GIS based risk management platform to evaluate economical losses in a region from fire following an earthquake. [less ▲]

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See detailBaltic seagrass meadows as a sediment carbon sink
Jankowska, Emilia; Włodarska-Kowalczuk, Maria; Michel, Loïc ULg et al

Conference (2015, September 25)

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See detailMedicinal plants, malaria and biotechnology
Frederich, Michel ULg; Jansen, Olivia ULg; Muganga, Raymond et al

Conference (2015, September 24)

The first part of the talk will be dedicated to the investigation of medicinal plants with the objective to identify new antimalarial treatments. According to the last World Malaria Report [1], there were ... [more ▼]

The first part of the talk will be dedicated to the investigation of medicinal plants with the objective to identify new antimalarial treatments. According to the last World Malaria Report [1], there were 584 000 deaths for 198 millions malaria cases worldwide in 2013. Particularly, the disease caused an estimated 437 000 African children died before their fifth birthday, still in 2013. Malaria is caused by a parasite, Plasmodium sp. and transmitted by Anopheles mosquitoes. The problem of parasite resistance towards common available medicines such as chloroquine, mefloquine, quinine, is increasing. In this context, the vegetal kingdom remains the main source of pharmacologically active compounds against this parasitic infection as attested by the famous quinine, isolated from Cinchona sp., artemisinin extracted from Artemisia annua and also atovaquone derived from lapachol found in several Bignoniaceae. All these substances are related to plants with traditional use against fever and malaria. Beside these well-known examples, various new antiplasmodial compounds are frequently discovered from Nature, particularly following an ethnopharmacological approach, as reviewed by several authors in recent years [2-6]. Then, the pharmacological and phytochemical study of plants from traditional pharmacopoeias can be of first interest not only to discover new antimalarial “lead compounds”, but also to valorize local vegetal species whose efficacy and safety would have been demonstrated in laboratory and by clinical investigations [7,8]. Some results obtained with Dicoma tomentosa from Burkina-Faso [9] and Terminalia mollis from Rwanda [10] will be presented. In the second part of the talk, two applications of biotechnology for the production of artemisinin and paclitaxel and then some works developed at the ‘Université de la Réunion’ will be presented. In the framework of this collaboration, Psiadia arguta, an endemic plant from Reunion Island, which is known to have cytotoxic, anti-plasmodial and anti-inflammatory properties, was subjected to micropropagation. The objective of the work was to compare the biological properties and the phytochemical composition of callus, vitroplants and acclimatized plants of Psiadia arguta [11]. 1. WHO, World Malaria Report 2014, December 2014, Geneva (http://www.who.int/malaria/publications/world_malaria_report_2014/en/). 2. Batista R, Silva Ade J Jr, de Oliveira AB: Plant-derived antimalarial agents: new leads and efficient phytomedicines. Part II. Non-alkaloidal natural products. Molecules 2009, 14:3037-72. 3. Bero J, Frédérich M, Quetin-Leclercq J : Antimalarial compounds isolated from plants used in traditional medicine. Journal of Pharmacy and Pharmacology 2009, 61:1401–1433. 4. Bero J and Quetin-Leclercq J: Natural products published in 2009 from plants traditionally used to treat malaria. Planta Medica 2011, 77:631-40. 5. Kaur K, Jain M, Kaur T, Jain R: Antimalarials from nature. Bioorganic & Medicinal Chemistry 2009, 17:3229–3256. 6. Nogueira CR and Lopes LMX: Antiplasmodial Natural Products. Molecules 2011, 16:2146-2190 7. Ginsburg H and Deharo E: A call for using natural compounds in the development of new antimalarial treatments – an introduction. Malaria Journal 2011, 10 (suppl. 1):S1 8. Willcox M, Graz B, Falquet J, Diakite C, Giani S, Diallo D: A “reverse pharmacology” approach for developing an antimalarial phytomedicine. Malaria journal 2011, 10(suppl1):S8 9. Jansen, O., Tits, M., Angenot, L., Nicolas, J.-P., De Mol, P., Nikiema, J.-B., & Frédérich, M : Anti-plasmodial activity of Dicoma tomentosa (Asteraceae) and identification of urospermal A-15-O-acetate as the main active compound. Malaria Journal 2012, 11, 289. 10. Muganga, R., Angenot, L., Tits, M., & Frédérich, M : In vitro and in vivo antiplasmodial activity of three Rwandan medicinal plants and identification of their active compounds. Planta Medica 2013, 80(6), 482-489. 11. Mahy Justine, Comparative study of biological activities and analysis of volatile compounds of Psiadia arguta in various cultures: vitroplants and acclimatized plants. Mémoire de M2, 2013, Université de Liège/Université de la Réunion. [less ▲]

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See detailMyoferlin: an indispensable component in VEGFA secretion by pancreas cancer cells.
Fahmy, Karim ULg

Poster (2015, September 24)

In this poster, our laboratory showed the importance of myoferlin, a biomarker of pancreas cancer, in the controle of VEGF-A mediated angiogenesis. Our laboratory showed that silencing myoferlin in ... [more ▼]

In this poster, our laboratory showed the importance of myoferlin, a biomarker of pancreas cancer, in the controle of VEGF-A mediated angiogenesis. Our laboratory showed that silencing myoferlin in pancreas cancer cells, BxPC-3, provoques a decrease in cell prolifération in vitro and a decrease in tumor volumes in animal model. Myoferlin silencing also provokes a decrease in VEGF-A secretion in the conditioned medium and that decrease was abserved in the animal model as a decrease in microvessels dencity. It appeared that this decrease in secretion is due to a a blockage in the exocytosis. Our data also showed a significate correlation between myoferlin expression and microvessels density in patients section. [less ▲]

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Peer Reviewed
See detailPerformances of a simple exhaust mechanical ventilation coupled to a mini heat pump: modeling and experimental investigations
Ransy, Frédéric ULg; Gendebien, Samuel ULg; Lemort, Vincent ULg

Conference (2015, September 24)

According to the European directive 2012/27/EU of October 2012 on energy efficiency, buildings represented 40 % of the EU’s final energy consumption in 2011. The major part of this energy consumption is ... [more ▼]

According to the European directive 2012/27/EU of October 2012 on energy efficiency, buildings represented 40 % of the EU’s final energy consumption in 2011. The major part of this energy consumption is due to the residential sector for space heating and domestic hot water production. Moreover, buildings are crucial to achieve the EU objective of reducing greenhouse gas emissions by 80-95 % by 2050 compared to 1990. In order to reduce these greenhouse gas emissions, retrofit measures regarding insulation and air-tightness have to be taken. However, such improvements of the building envelope lead to a relative increase in consumption related to ventilation. Indeed, according to Orme (2001), Roulet et al. (2001) and Fouih et al. (2012), the heating demand due to ventilation can reach more than 50 % of the total building heating demand for new and retrofitted buildings. To reduce the energy consumption due to ventilation, exhaust air heat pumps (EAHPs) can be used instead of the traditional heat recovery with an air-to-air heat exchanger. EAHPs recover heat from the exhaust air of the ventilation system to produce domestic hot water and space heating. According to Fehrm et al. (2002), this technology is already widely used in the northern countries such as Germany and Sweden. In fact, according to Fracastoro et al. (2010), efficiencies of EAHPs are higher than those obtained with outside air or geothermal heat pumps in certain conditions, whatever the climate location. Berg et al. (2010) have monitored three houses in Sweden equiped with exhaust air heat pumps. The seasonal performance factor (SPF) values were all within the range 1.4-1.7. This factor takes into account the energy consumption of the heat pumps and the auxiliary heating systems. A 17 kW exhaust air heat pump has also been tested by Mikola et al. (2014). The measured SPF for the heat pump only (without taking into account the auxiliary heating system) was about 2.9-3.4 in winter and 3 in the summer. Exhaust air heat pumps coupled with simple exhaust mechanical ventilation systems have many advantages compared to traditional balanced systems with heat recovery: • Only one fan is necessary and the duct system is simpler. Consequently, EAHPs are suitable for retrofitted buildings. • The heat pump can provide the whole part of the heating demand related to domestic hot water and 50 % of the heating demand related to space heating, according to Fracastoro et al. (2010). • The heat pump can also provide active cooling by inversing the refrigerating cycle. • The heat pump performance is high and remains constant with outdoor temperature changes since the temperature of the heat sink is constant (20°C). As a result, the system is cost-effective. • The system is compact, quiet and requires little maintenance. In the present paper, the energetic performances of an exhaust air heat pump are assessed through numerical and experimental studies. The thermal capacity of the machine is 1.5 kW when the inside air temperature is 20°C and the outside water temperature is 35°C. The heat pump is therefore ideally suited for new or retrofitted buildings. The system including a mechanical exhaust ventilation system and an exhaust air heat pump is first presented. Secondly, the heat pump model used afterwards to determine the heat pump seasonal performance factor is described. Thirdly, the model is calibrated to fit the measurement data. Finally, the heat pump model is coupled to a building model to determine the annual performance of the system. The system is compared to a traditional balanced ventilation system with heat recovery in terms of primary energy consumption, for different heating and DHW production systems (electric heater, heat pump, gas condensing boiler). [less ▲]

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See detailOn generalized Hölder spaces
Kreit, Damien; Nicolay, Samuel ULg

Conference (2015, September 24)

We introduce generalized pointwise Hölder spaces as the point wise version of generalized uniform Hölder spaces. These last ones can be seen as a special case of generalized Besov spaces.

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See detailVALIDATION RELEVANCE OF ANALYTICAL METHODS IN BIOTECHNOLOGY
Marini Djang'Eing'A, Roland ULg; Hubert, Philippe ULg

Conference (2015, September 24)

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See detailPerformances analytiques d’un biomarqueur : dialogue
CAVALIER, Etienne ULg

Conference (2015, September 23)

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See detailUse of the wavelet theory as a tool to investigate the l-abelian complexity of a sequence
Kleyntssens, Thomas ULg; Nicolay, Samuel ULg; Vandomme, Elise ULg et al

Poster (2015, September 23)

The concept of k-automatic sequences is at the intersection of number theory and formal language theory. It has been generalized by the notion of k-regularity that allows to study sequences with values in ... [more ▼]

The concept of k-automatic sequences is at the intersection of number theory and formal language theory. It has been generalized by the notion of k-regularity that allows to study sequences with values in a (possibly infinite) ring. This concept provides us with structural information about how the different terms of the sequence are related to each other. They are many different notions related to the measure of complexity of an infinite sequence w. A classical approach is its factor complexity. In an abelian context, the analogue to the factor complexity is the abelian complexity where the number of distinct factors of length n is counted up to abelian equivalence. The notion of abelian complexity was extended to that of l-abelian complexity. In this talk, I propose to use tools from the wavelet theory to analyze the l-abelian complexity. For the numerical simulations, I apply the wavelet leaders method that allows to study the pointwise regularity of signals. [less ▲]

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See detailStratospheric HCl increasing again, caused by dynamic variability, driven by increased tropopsheric wave activity
Notholt, J; Mahieu, Emmanuel ULg; Pfloeger, F et al

Conference (2015, September 22)

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See detailFormation flying metrology for the ESA-PROBA3 mission: the Shadow Position Sensors (SPS) silicon photomultipliers (SiPMs) readout electronics
Focardi, M.; Bemporad, A.; Buckley, S. et al

in Proc. SPIE Volume 9604 Solar Physics and Space Weather Instrumentation VI (2015, September 21)

The European Space Agency (ESA) is planning to launch in 2018 the PROBA3 Mission, designed to demonstrate the inorbit formation flying (FF) attitude capability of its two satellites and to observe the ... [more ▼]

The European Space Agency (ESA) is planning to launch in 2018 the PROBA3 Mission, designed to demonstrate the inorbit formation flying (FF) attitude capability of its two satellites and to observe the inner part of the visible solar corona as the main scientific objective. The solar corona will be observed thanks to the presence on the first satellite, facing the Sun, of an external occulter producing an artificial eclipse of the Sun disk. The second satellite will carry on the coronagraph telescope and the digital camera system in order to perform imaging of the inner part of the corona in visible polarized light, from 1.08 Rsun up to about 3 Rsun. One of the main metrological subsystems used to control and to maintain the relative (i.e. between the two satellites) and absolute (i.e. with respect to the Sun) FF attitude is the Shadow Position Sensor (SPS) assembly. It is composed of eight micro arrays of silicon photomultipliers (SiPMs) able to measure with the required sensitivity and dynamic range the penumbral light intensity on the Coronagraph entrance pupil. In the following of the present paper we describe the overall SPS subsystem and its readout electronics with respect to the capability to satisfy the mission requirements, from the light conversion process on board the silicon-based SPS devices up to the digital signal readout and sampling. [less ▲]

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See detailSignificance of the occulter diffraction for the PROBA3/ASPIICS formation flight metrology
Landini, F.; Bemporad, A.; Focardi, M. et al

in Proc. SPIE Volume 9604 Solar Physics and Space Weather Instrumentation VI (2015, September 21)

PROBA-3/ASPIICS is a formation Flying coronagraph selected by ESA and currently in its C/D phase. It is constituted by two spacecrafts (OSC, Occulter SpaceCraft, carrying the occulter, diameter 142 cm ... [more ▼]

PROBA-3/ASPIICS is a formation Flying coronagraph selected by ESA and currently in its C/D phase. It is constituted by two spacecrafts (OSC, Occulter SpaceCraft, carrying the occulter, diameter 142 cm, and CSC, Coronagraph SpaceCraft, with the telescope) separated by ~144 m, kept in strict alignment by means of an active custom system. The alignment active system most critical components are the Shadow Positioning Sensors (SPS), a series of Si-PM (Silicon Photomultiplier) measuring the penumbra generated by the occulter. The arrangement of the SPSs around the telescope entrance aperture is defined as a trade-off between mechanical constraints and maximum sensitivity to misalignments. The signal detected by the SPSs can be approximately simulated with a geometrical analysis based on the variation of the penumbra generated by the external occulter. The stray light generated by the diffraction from the external occulter may affect the SPSs signal. It is mandatory to carefully evaluate its level in order to refine the active alignment adjustment algorithm. This work is dedicated to the description of the preliminary investigation performed in order to evaluate the impact of the diffraction on the SPSs signal. [less ▲]

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See detailDesign and modelisation of ASPIICS optics
Galy, Camille ULg; Fineschi, S.; Galano, D. et al

in Proc. SPIE Volume 9604 Solar Physics and Space Weather Instrumentation VI (2015, September 21)

In the framework of development of ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun), the Centre Spatial de Liege is responsible of the optical design ... [more ▼]

In the framework of development of ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun), the Centre Spatial de Liege is responsible of the optical design of the coronagraph and the optics will be manufactured by TOPTEC. The particularity of this coronagraph is to have an external occulter located 150 m ahead of the first imaging lens. This external occulter is re-imaged on an internal occulter which function is - as in a classical externally occulted Lyot coronagraph - to block the sun light diffracted by the external occulter and to reduce the straylight on the detector. The selection of this configuration is driven by the requirement to observe the corona as close as possible to the solar limb (i.e. 1 RSun) without imaging the limb itself. A requirement of 1.08 RSun is specified at optical design level to grant 1.2 Rsun at instrument level. The coronograph instrument is designed to have a field of view of 1.6° x 1.6° with a resolution of less than 6 arcsec. Its performances are limited by diffraction in a 530 – 590 nm wavelength range. This paper presents the optical design and demonstrates that by design the requirements are fulfilled within the misalignment, manufacturing and thermo-elastic error contributions. [less ▲]

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See detailOPSE metrology system onboard of the PROBA3 mission of ESA
Loreggia, D.; Bemporad, A.; Capobianco, G. et al

in Proc. SPIE Volume 9604 Solar Physics and Space Weather Instrumentation VI (2015, September 21)

In recent years, ESA has assessed several mission involving formation flying (FF). The great interest in this topics is mainly driven by the need for moving from ground to space the location of next ... [more ▼]

In recent years, ESA has assessed several mission involving formation flying (FF). The great interest in this topics is mainly driven by the need for moving from ground to space the location of next generation astronomical telescopes overcoming most of the critical problems, as example the construction of huge baselines for interferometry. In this scenario, metrology systems play a critical role. PROBA3 is an ESA technology mission devoted to in-orbit demonstration of the FF technique, with two satellites, an occulter and a main satellite housing a coronagraph named ASPIICS, kept at an average inter-distance by about 144m, with micron scale accuracy. The guiding proposal is to test several metrology solution for spacecraft alignment, with the important scientific return of having observation of Corona at never reached before angular field. The Shadow Position Sensors (SPS), and the Optical Position Emitters Sensors (OPSE) are two of the systems used for FF fine tracking. The SPS are finalized to monitor the position of the two spacecraft with respect to the Sun and are discussed in dedicated papers presented in this conference. The OPSE will monitor the relative position of the two satellites and consists of 3 emitters positioned on the rear surface of the occulter, that will be observed by the coronagraph itself. By following the evolution of the emitters images at the focal plane the alignment of the two spacecrafts is retrieved via dedicated centroiding algoritm. We present an overview of the OPSE system and of the centroiding approach. [less ▲]

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See detailDesign status of ASPIICS, an externally occulted coronagraph for PROBA-3
Renotte, Etienne ULg; Alia, A.; Bemporad, A. et al

in Proc. SPIE Volume 9604 Solar Physics and Space Weather Instrumentation VI (2015, September 21)

The “sonic region” of the Sun corona remains extremely difficult to observe with spatial resolution and sensitivity sufficient to understand the fine scale phenomena that govern the quiescent solar corona ... [more ▼]

The “sonic region” of the Sun corona remains extremely difficult to observe with spatial resolution and sensitivity sufficient to understand the fine scale phenomena that govern the quiescent solar corona, as well as phenomena that lead to coronal mass ejections (CMEs), which influence space weather. Improvement on this front requires eclipse-like conditions over long observation times. The space-borne coronagraphs flown so far provided a continuous coverage of the external parts of the corona but their over-occulting system did not permit to analyse the part of the white-light corona where the main coronal mass is concentrated. The proposed PROBA-3 Coronagraph System, also known as ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun), with its novel design, will be the first space coronagraph to cover the range of radial distances between ~1.15 and 3 solar radii where the magnetic field plays a crucial role in the coronal dynamics, thus providing continuous observational conditions very close to those during a total solar eclipse. PROBA-3 is first a mission devoted to the in-orbit demonstration of precise formation flying techniques and technologies for future European missions, which will fly ASPIICS as primary payload. The instrument is distributed over two satellites flying in formation (approx. 150m apart) to form a giant coronagraph capable of producing a nearly perfect eclipse allowing observing the sun corona closer to the rim than ever before. The coronagraph instrument is developed by a large European consortium including about 20 partners from 7 countries under the auspices of the European Space Agency. This paper is reviewing the recent improvements and design updates of the ASPIICS instrument as it is stepping into the detailed design phase. [less ▲]

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See detailAir-sea ice gases exchange: update of recent findings, outcomes from sea ice models, caveats and open questions
Delille, Bruno ULg; Zhou, Jiayun; Kotovitch, Marie ULg et al

Conference (2015, September 21)

There are growing evidences that sea ice exchanges climate gases with the atmosphere. We will rapidly present a state of the art of current large scale assessment of spring and summer uptake of ... [more ▼]

There are growing evidences that sea ice exchanges climate gases with the atmosphere. We will rapidly present a state of the art of current large scale assessment of spring and summer uptake of atmospheric CO2. We will challenge these assessments with 1) new evidence of significant winter CO2 release for winter experiments 2) new finding of the role of bubbles formation and transport within sea ice and 3) impurities expulsion derived from combined artificial ice experiment and modelling. Finally, comparison of air-ice fluxes derived from automated chamber and micrometeorological method and, mechanistic and box models show significant discrepancies that suggest that the contribution of sea ice to the air-ocean fluxes of CO2 remain an open question. We will also highlight that sea ice contribute to the fluxes of other gases as CH4 ,N2O and DMS [less ▲]

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See detailThe Shadow Positioning Sensors (SPS) for formation flying metrology on-board the ESA-PROBA3 mission
Bemporad, A.; Baccani, C.; Capobianco, G. et al

in Proc. SPIE Volume 9604 Solar Physics and Space Weather Instrumentation VI (2015, September 21)

PROBA3 is an ESA technology mission devoted to in-orbit demonstration of the formation flight (FF) technique, with two satellites kept at an average inter-distance by about 144 m. The ASPIICS instrument ... [more ▼]

PROBA3 is an ESA technology mission devoted to in-orbit demonstration of the formation flight (FF) technique, with two satellites kept at an average inter-distance by about 144 m. The ASPIICS instrument on-board PROBA3 will be the first ever space-based coronagraph working on one satellite and having the external occulter located on the second satellite, thus allowing observations of the inner solar corona with unprecedented reduction of stray light. During the observational periods, the FF configuration will be maintained with very high precision and two different techniques will be implemented: the use of Shadow Positioning Sensors (SPS) located on the Coronagraph Spacecraft (diodes measuring the penumbral light intensity on the entrance pupil plane) and the use of Occulter Position Sensor LEDs (OPSE) located on the back side of the Occulter Spacecraft. This paper will review the main instrumental requirements on the SPS needed to determine the 3-dimensional relative positioning of the two PROBA3 satellites with the high precision and frequency. [less ▲]

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See detailPathways of recurrent high-grade squamous intraepithelial lesions of the cervix
Herfs, Michael ULg

Conference (2015, September 20)

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Peer Reviewed
See detailNon-invasive markers: the role of G-CSF?
Munaut, Carine ULg

Conference (2015, September 19)

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