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See detailThe role of segmentation and investor recognition through the lens of cross-listing activity
Mouchette, Xavier ULg; Muller, Aline ULg; Carrieri, Francesca

Conference (2014, June)

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See detailL’effet des dispositifs d’intermédiation sur les trajectoires professionnelles des travailleurs. Le cas d’un bureau de recrutement, recherche et sélection de personnel.
Gérard, Julie ULg

Conference (2014, June)

Au cours de ces dernières années, le souci d’allier flexibilité et sécurité au travail a conduit à l’essor considérable des métiers de l’intermédiation (Orianne et Maroy, 2008). En particulier dans le ... [more ▼]

Au cours de ces dernières années, le souci d’allier flexibilité et sécurité au travail a conduit à l’essor considérable des métiers de l’intermédiation (Orianne et Maroy, 2008). En particulier dans le domaine de l’accompagnement et du développement de carrière, divers dispositifs privés d’aide et de suivi ont vu le jour afin de contribuer à l’amélioration des conditions de travail et d’assister les travailleurs dans leurs transitions professionnelles. Par leur action, ces nouveaux dispositifs n’hésitent pas à complexifier les temporalités sociales en créant de nouvelles opportunités d’emploi et en redéfinissant les rythmes de carrière. À l’aide d’une étude de cas dans le secteur du recrutement belge, nous analyserons la capacité d’un processus de mise en emploi à remplir de tels objectifs dans un contexte de gestion mixte du marché du travail. Approchée d’une manière qualitative (entretiens semi-directifs et observations), nous étudierons l’apport de cette agence de placement au travers d’un cadre théorique qui intègre les concepts de dispositif (Foucault, 1977 ; Peeters et Charlier, 1999 ; Raffnsoe, 2008) et de réseaux sociaux (Grossetti 2005, 2008 et 2011). Nous montrerons qu’un plus de régir l’offre et la demande de travail, ce dispositif d’intermédiation, par son système de cooptation et son accompagnement de carrière, assure la fluidification du marché et sécurise la dynamique des transitions professionnelles. [less ▲]

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See detailUsing intensive multiyear fish-pass monitoring to analyse seasonal upstream movement patterns of patrimonial holobiotic potomadromous fish species in a medium size river
Benitez, Jean-Philippe ULg; Nzau Matondo, Billy ULg; Dierckx, Arnaud ULg et al

in Proceedings of the 10th International Conference on Ecohydraulics (2014, June)

Belgian rivers are fragmented by numerous obstacles which considerably limit the free access of fish to functional habitats. Fish-passes are major tools used to increase stream continuity and improve ... [more ▼]

Belgian rivers are fragmented by numerous obstacles which considerably limit the free access of fish to functional habitats. Fish-passes are major tools used to increase stream continuity and improve connectivity in the upstream direction. Using two modern multispecies fish-passes, this study aims to investigate multiyear abundance of holobiotic potamodromous fish and their seasonal movement patterns in relation with environmental factors. The fish passes were monitored continuously during 5 and 7 years and are located in two Belgian streams: the (19.3m³.s-1) and the Berwinne (1.9m³.s-1). Results revealed the presence of 20 different fish species, 14 species in the Berwinne and 19 species in the occurrence, salmonids and cyprinids species were predominant. A great interspecific and intraspecific variability in capture periodicity and in terms of stimulation by combination of factor environmental was observed. This study highlights the complexity and the omnipresence of holobiotic potamodromous fish movements at different life stages, in medium size river and brings new information on fish passes efficiency and use by these poorly known species. [less ▲]

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See detailDouble Sweep Preconditioners for propagation problems solved by Optimized Schwarz Methods
Vion, Alexandre ULg; Geuzaine, Christophe ULg

in Proceedings of the 6th International Conference on Advanced COmputational Methods in ENgineering, ACOMEN 2014 (2014, June)

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See detailGenetic diversity, structure and parentage analysis within several European apple germplasm collections assessed by microsatellite markers
Durel, Charles-Eric; Denancé, Caroline; Ravon, Elisa et al

Conference (2014, June)

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See detailCan we interpret linear kernel machine learning models using anatomically labelled regions?
Schrouff, Jessica ULg; Monteiro, Joao; Joao Rosa, Maria et al

Poster (2014, June)

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See detailMODEL PREDICTIVE CONTROL OF CONGESTION AND VOLTAGE PROBLEMS IN ACTIVE DISTRIBUTION NETWORKS
Soleimani Bidgoli, Hamid ULg; Glavic, Mevludin ULg; Van Cutsem, Thierry ULg

in Proc. of CIRED Workshop 2014 (2014, June)

This paper presents a centralized control scheme, inspired of Model Predictive Control (MPC), to manage thermal overloads and correct abnormal voltages in real-time. The control scheme is able to smoothly ... [more ▼]

This paper presents a centralized control scheme, inspired of Model Predictive Control (MPC), to manage thermal overloads and correct abnormal voltages in real-time. The control scheme is able to smoothly bring the system within the desired limits, taking into account its near-future evolution. The control method effectiveness is illustrated on a 20-kV, 32-bus network hosting four distributed generation units. [less ▲]

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See detailCrime Hotspots In Belgium: Spatial He terogeneity In The Multivariate Regression Model?
Trotta, Marie ULg

Conference (2014, June)

Place attractiveness is an important property to consider when modelling the spatial behaviour of a serial offender. Small spatial units are privileged in the recent literature to study the crime ... [more ▼]

Place attractiveness is an important property to consider when modelling the spatial behaviour of a serial offender. Small spatial units are privileged in the recent literature to study the crime concentration-urban backcloth relationship, with the drawback of focusing on a single city. However, the urban backcloth is also shaped by the inter-cities and city-hinterland relationships. Our objective is to model the concentration of sexual offences for entire Belgium, at the very precise scale of the statistical sector in order to take into account the role of the urban hierarchy. Methods: We analyse the ViCLAS data for Belgium between 2004 and 2011. Specifically, we study the relationship between the concentration of initial contact scenes and socio-economic characteristics and facilities of the statistical sector, using two spatial models. First, we computed a spatial lag zero-inflated model (ZINB) in order to evaluate the global predictive capacities of the model. Then, a Poisson geographically-weighted regression (GWR) was run to study the spatial heterogeneity for each of the explanatory variables. Results: The zero-inflated negative binomial model with spatial lag recovers the neighbourhood environmental quality, the concentration of economic and cultural activities, and drinking places as major significant factors (Mc Fadden’s pseudo-r² of 0.2). The Poisson geographically-weighted regression underestimates the crime concentrations but highlights the spatial heterogeneity [less ▲]

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See detailETEROGENEITÀ GENETICA DI NOROVIRUS BOVINI IDENTIFICATI IN ITALIA
Di Felice, Eliabetta; Di Profio, Federica; Melegari, Irene et al

Poster (2014, June)

I norovirus (NoV) sono piccoli virus a RNA monocatenario appartenenti alla famiglia Caliciviridae. Sulla base dell’analisi di sequenza del gene ORF2 codificante per la proteina capsidica VP1, i NoV sono ... [more ▼]

I norovirus (NoV) sono piccoli virus a RNA monocatenario appartenenti alla famiglia Caliciviridae. Sulla base dell’analisi di sequenza del gene ORF2 codificante per la proteina capsidica VP1, i NoV sono attualmente classificati in sei genogruppi (G), con GI, GII e GIV responsabili di gastroenterite nell’uomo. Calicivirus enterici morfologicamente simili a NoV umani sono stati identificati per la prima volta in vitelli diarroici nel Regno Unito nel 1978 e in Germania nel 1980. Il sequenziamento nucleotidico dell’intero genoma ha permesso di classificare i NoV bovini (BoNoV) all’interno del genogruppo III in due genotipi, GIII.1 (prototipo Bo/Jena/80/DE) e GIII.2 (prototipo Bo/Newbury/76/UK). I BoNoV hanno una diffusione mondiale con una maggiore prevalenza di virus GIII.2-like. Tuttavia, studi recenti basati sull’analisi nucleotidica a livello della giunzione fra la polimerasi (RdRp) ed il capside, hanno dimostrato la circolazione di ceppi ricombinanti. Nel presente lavoro vengono riportati i risultati di un’indagine per la ricerca e tipizzazione di BoNoV condotta su quattro allevamenti bovini ubicati nelle province di Teramo e Pescara. A tal fine, 104 tamponi rettali collezionati da vitelli asintomatici sono stati sottoposti a nested RT-PCR impiegando due set di primer specifici per BoNoV in grado di amplificare un frammento di 326 bp della RdRp. L’RNA di BoNoV è stato identificato nel 10,5% (11/104) degli animali testati. L'analisi di sequenza ha evidenziato per nove sequenze un’elevata identità nucleotidica (nt) (88-96%) con i ceppi GIII.2-like, mentre per due è stata rilevata la maggiore identità (87-90% nt) con i BoNoV GIII.1-like. Per sette ceppi è stata ottenuta anche una sequenza di circa 750 bp che includeva oltre che la regione parziale della RdRp, la regione 5’ capsidica. Sulla base dell’analisi molecolare, cinque ceppi sono risultati strettamente correlati con BoNoV GIII.2-like, mentre solo uno dei due ceppi con polimerasi GIII.1-like, ha mostrato la maggiore identità nucleotidica nei confronti di BoNoV appartenenti al genotipo 1. Il ceppo 80/TE/IT che possedeva una polimerasi GIII.1-like, a livello capsidico ha mostrato la più alta identità con ceppi GIII.2-like, suggerendo un fenomeno di ricombinazione a livello della giunzione ORF1/ORF2. [less ▲]

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See detailThe role of segmentation and investor recognition through the lens of cross‐listing activity
Mouchette, Xavier ULg; Muller, Aline ULg; Carrieri, Francesca

Conference (2014, June)

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See detailPhilosophy of economic security of organization: The constructivist approach
Shutyak, Yuliya ULg

Conference (2014, June)

The purpose of this paper is to present the concept of economic security of the organization. Guiding by the constructivism approach, the author conducts a narrative literature review on economic security ... [more ▼]

The purpose of this paper is to present the concept of economic security of the organization. Guiding by the constructivism approach, the author conducts a narrative literature review on economic security of organization in parallel with well-known theories of business management.The presented in the paper ideas are an impulse for a new wave in organizational research basing on a new globalizing theoretical framework. The proposed approach to organizational management through the prism of security allows connecting disjoined concepts used in organizational studies and highlights aspects important for organizational survival and growth but mostly overlooked by scientists. The paper’s value consists in evolving of a relatively unexploited concept of economic security of the organization. [less ▲]

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See detailSorting of crop residues and fossil bones from soil by NIR Hyperspectral Imaging
Vincke, Damien; Eylenbosch, Damien ULg; Baeten, Vincent et al

Poster (2014, June)

Soil is a complex matrix containing a wide variety of constituents of interest for disciplines like agronomy or archaeology; it could either be crop residues like roots and straws or bones and ceramics ... [more ▼]

Soil is a complex matrix containing a wide variety of constituents of interest for disciplines like agronomy or archaeology; it could either be crop residues like roots and straws or bones and ceramics. Current challenges comprise the detection of these constituents as well as the assessment of their qualitative parameters by means of fast and non-destructive analytical methods. The scope of this work is to present two applications using Near Infrared Hyperspectral Imaging (NIR-HSI) combined with chemometrics to sort constituents of soil and to assess their qualitative parameters. The first application concerns the feasibility study of using NIR-HSI to sort crop residues such as roots and straws in soil. The second application aim to develop a method to assess the level of collagen preservation in fossil bones. [less ▲]

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See detailAnalysis versus synthesis for trending of gas-path measurement time series
Borguet, Sébastien ULg; Léonard, Olivier ULg; Dewallef, Pierre ULg

in Proceedings of ASME Turbo Expo 2014 (2014, June)

Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear ... [more ▼]

Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear filters such as the exponentially weighted moving average filter are traditionally used for noise removal. Unfortunately, these low-pass filters distort trend shifts indicative of faults, which increases the detection delay. The present paper investigates two new approaches to non-linear filtering of time series. On one hand, the synthesis approach reconstructs the signal as a combination of elementary signals chosen from a pre-defined library. On the other hand, the analysis approach imposes a constraint on the shape of the signal (e.g., piecewise constant). Both approaches incorporate prior information about the signal in a different way, but they lead to trend filters that are very capable at noise removal while preserving at the same time sharp edges in the signal. This is highlighted through the comparison with a classical linear filter on a batch of synthetic data representative of typical engine fault profiles. [less ▲]

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See detailStereoselective synthesis of peptidoglycan fragments on solid support
Simon, Justine ULg; Lamborelle, Nicolas ULg; Joris, Bernard ULg et al

Poster (2014, June)

The mammalian proteins, Nod1 and Nod2, are able to recognize peptidoglycan motifs during bacterial infection. Interestingly, Nod1 is a detector of peptides and muropeptides containing the meso-2,6 ... [more ▼]

The mammalian proteins, Nod1 and Nod2, are able to recognize peptidoglycan motifs during bacterial infection. Interestingly, Nod1 is a detector of peptides and muropeptides containing the meso-2,6-diaminopimelic acid (m-A2pm), a non-proteinogenic amino acid found in Gram- bacteria. In this work, we describe a synthesis of peptidoglycan motifs entirely on solid support. Solid-Phase Peptide Synthesis (SPPS), Cross Metathesis (CM) and sugar chemistry are three methods to anchor respectively amino acids, m-A2pm and sugars derivatives on a resin as solid support. [less ▲]

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See detailThe role of segmentation and investor recognition through the lens of cross-listing activity
Mouchette, Xavier ULg; Carrieri, Francesca; Muller, Aline ULg

Conference (2014, June)

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See detailBridging the gap between Do-It-Yourself urban practices and urban systems
Farah, Jihad ULg; Cabrera Quispe, Juan Edson ULg; Teller, Jacques ULg

Conference (2014, June)

In contemporary fragmented cities, DIY urbanism is seen as a way to insure inclusiveness and cohesion by mobilizing citizens and improving urban space. However, the capacity of DIY to go beyond local ... [more ▼]

In contemporary fragmented cities, DIY urbanism is seen as a way to insure inclusiveness and cohesion by mobilizing citizens and improving urban space. However, the capacity of DIY to go beyond local epiphenomena and contribute to a systemized way of city making is still an open question that is gaining increasing interest in literature and practice. In this article, we differ from answers provided in the literature to this question in that we are interested in the ways DIY practices could contribute to build from the bottom-up large-scale territories. We rely on Lévy-Strauss oppositions of the bricoleur vs. the engineer and the “savage” vs. the scientist to stress that DIY is instrumental and political. This leads us to consider DIY as a process of problem-solving and domos building where the operational and socio-spatial aspects of DIY are intrinsically linked and evolving together. It is by understanding both these aspects that we can understand the possibilities of, and limitations facing, the development of DIY on a larger territorial scale. We build on case studies in Cochabamba, Bolivia and Beirut, Lebanon. We argue that though it is possible to succeed to build on DIY to develop local territories and rely on these experiences to trace larger ones, the operational and political modes would invariably move towards more top-down comprehensive engineer-like approaches. [less ▲]

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See detailL’effet d’un dispositif public d’accompagnement et de formation belge sur les trajectoires professionnelles des demandeurs d’emploi
Gérard, Julie ULg

Conference (2014, June)

: Suite aux récents bouleversements économiques et sociaux touchant les pays de l’Union Européenne, de nombreux partenariats entre services publics d’emploi et agences d’emploi privées se sont développés ... [more ▼]

: Suite aux récents bouleversements économiques et sociaux touchant les pays de l’Union Européenne, de nombreux partenariats entre services publics d’emploi et agences d’emploi privées se sont développés et complexifiés, suivant une logique de gestion mixte du marché de l’emploi. Cette communication porte sur l’étude d’un partenariat public-privé entre un service public régional belge et un organisme de formation. À partir des apports conceptuels et théoriques de la sociologie de l’action publique et de la littérature propre aux agences d’emploi privées et aux partenariats public-privé, nous analyserons la capacité d’un dispositif public à assurer la remise à l’emploi de son public-cible. Pour ce faire, nous étudierons son rôle et ses effets sur les trajectoires professionnelles des demandeurs d’emploi y recourant. [less ▲]

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See detailURINARY AND SALIVARY CORTISOL IN LIQUID CHROMATOGRAPHY–TANDEM MASS SPECTROMETRY: METHOD VALIDATION AND EXPECTED VALUES DETERMINATION
LE GOFF, Caroline ULg; DELCOUR, Sandra ULg; PEETERS, Stéphanie ULg et al

in Clinical Chemistry & Laboratory Medicine (2014, June), 52(Special Suppl), 1241

BACKGROUND: Cortisol measurement is useful in evaluation of Cushing syndrome, adrenal insufficiency, mineralocorticoid excess and congenital adrenal hyperplasia. We developed a liquid ... [more ▼]

BACKGROUND: Cortisol measurement is useful in evaluation of Cushing syndrome, adrenal insufficiency, mineralocorticoid excess and congenital adrenal hyperplasia. We developed a liquid chromatography–tandem mass spectrometry (LCMS/MS) method for salivary and urinary cortisol and we determined the 95th percentile (p95) for the urinary and salivary cortisol. We compared them to the Mayo Clinic expected values. METHODS: Saliva at 8 am and 11 pm and 24h urine were obtained from 32 healthy (22 female, 34.3±9.3 yo) volunteers. We performed validation with the enoval software (Arlenda, Belgium). For the validation, we used water or urine with spiked known amounts of cortisol for the CORS and CTU respectively. For the CORS, samples were centrifuged, deuterium labelled cortisol was added as internal standard and the protein precipated by acetonitril. The supernatant was evaporated, dissolved in methanol acidified with acetic acid and analyzed by LCMS/MS. For CTU, samples were centrifuged, deuterium labelled cortisol was added as internal standard and diluted by the ammonium acetate and analyzed by LCMS/MS. At the Mayo Clinic, the expected values were 1-7.5 μg/L (7 a.m-9 a.m) and <1 μg/L (11-12 p.m) for CORS and 3.5-45 μg/24h (<18yo) for CTU. RESULTS: For the CTU, the with-in run did not exceed 3% (0.4-3%) and the between-run did not exceed 3.1% (0.4-3.1%) for 1.5-750 μg/L. The limit of quantification was 1.5 μg/L. The linearity was good between 1.5 and 750 μg/L. The recovery is 97.9±2.2% (95%CI for the mean: 92.4-101.1%). For the CORS, the with-in run and between run did not exceed 8% (1.9-8%) for 1.15-8.65 μg/L. The limit of quantification was 1.15 μg/L. The analyse presents a good linearity between 1.15 and 8.65 μg/L. The recovery is 99.9±2.9% (95%CI for the mean: 94.2-108.7%). The p95 for the CTU according to the CLSI C28-A3 was 33 μg/24h, and for the CORS was 5.42 μg/L at 8 am and 0.7 μg/L at 12 pm. CONCLUSIONS: Our developed method in liquid chromatography tandem mass spectrometry was validated for the measurement of urinary and salivary cortisol. Our findings indicate that the proposed analytical methods were suitable for routine purposes and useful in many pathological conditions.The expected values confirm these defined by the Mayo Clinic. [less ▲]

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See detailFigures du critique-écrivain, formes et pratiques du discours métalittéraire: Introduction et conclusions
Stienon, Valérie ULg; Van Nuijs, Laurence

Conference (2014, June)

Du XIXe siècle à nos jours, de nombreux écrivains ont combiné écriture de création et critique littéraire. À ces pratiques mêlées correspondent des statuts hybrides, dont celui de « critique-écrivain » ... [more ▼]

Du XIXe siècle à nos jours, de nombreux écrivains ont combiné écriture de création et critique littéraire. À ces pratiques mêlées correspondent des statuts hybrides, dont celui de « critique-écrivain » est peut-être le plus représentatif. Ce colloque se propose d’interroger cette figure bifide, en prenant en considération les divers paramètres de la critique littéraire en tant que pratique protéiforme, depuis l’institutionnalisation de la critique au XIXe siècle (critique journalistique, critique des écrivains et critique universitaire) jusqu’à la diversification moderne des types de discours critique (théorique, historique, médiatique, essayiste, romanesque). Comment les rapports entre critique et création sont-ils imaginés, confirmés voire inversés par les écrivains ? Par rapport à quels modèles et repoussoirs les écrivains se définissent-ils en critiques ou en créateurs (ceux, par exemple, du théoricien, de l’essayiste, du chroniqueur, du sociologue ou encore du polémiste) ? Pourquoi la postérité a-t-elle retenu comme critiques des auteurs qui ont par ailleurs investi ou approché une production spécifiquement littéraire ? Et comment ces rapports se renégocient-ils tout au long de l’histoire de la critique ? [less ▲]

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See detailInhibitors of glycosylhydrolases as potential insecticides : focus on aphid model
Bosquée, Emilie ULg; Vandermoten, Sophie; Richel, Aurore ULg et al

Poster (2014, June)

Beside conventional neurotoxic compounds, new kinds of insecticides are investigated and new specific targets are in current research. According to the energy metabolic pathway, several enzymes are ... [more ▼]

Beside conventional neurotoxic compounds, new kinds of insecticides are investigated and new specific targets are in current research. According to the energy metabolic pathway, several enzymes are interesting to bring potential specific control of arthropods. Indeed, glycosylhydrolase group is very diversified from glucanases to trehalases, until chitinases. Different kinds of inhibitors were here tested to determine their potential role as new targetted aphicides. After different assays using the selected inhibitors in artificial diets, the most efficient molecules at 50-100 μg ml-1were kept for further proteomic tasks. The proteome patterns of aphids related to different inhibitor treatments were determined by two dimension electrophoresis, 2D-Differencial In Gel Expression (2D-Dige) coupled with mass spectrometry (ESI-MS-MS and Maldi-Tof-MS-MS) and data bank investigations. Particular proteins of interest were selected and accurately characterised with both fundamental but also applied views. Not only the carbohydrate metabolic pathway was disturbed with the use of glycosylhydolases inhibitors, other primary functions were also modified (amino acid synthesis, stress response, etc). This proteomic approach was discussed as an interesting and reliable tool to study the biologically involved proteins from aphids in response to specific tested enzymatic inhibitors with further ideas to be promoted as new insecticides to control insect pests. [less ▲]

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See detailPrediction of macroscopic mechanical properties of a polycrystalline microbeam subjected to material uncertainties
Lucas, Vincent ULg; Wu, Ling ULg; Arnst, Maarten ULg et al

in Cunha, Álvaro; Caetano, Elsa; Ribeiro, Pedro (Eds.) et al Proceedings of the 9th International Conference on Structural Dynamics, EURODYN 2014 (2014, June)

The first resonance frequency is a key performance characteristic of MEMS vibrometers. In batch fabrication, this first resonance frequency can exhibit scatter owing to various sources of manufacturing ... [more ▼]

The first resonance frequency is a key performance characteristic of MEMS vibrometers. In batch fabrication, this first resonance frequency can exhibit scatter owing to various sources of manufacturing variability involved in the fabrication process. The aim of this work is to develop a stochastic multiscale model for predicting the first resonance frequency of MEMS microbeams constituted of polycrystals while accounting for the uncertainties in the microstructure due to the grain orientations. At the finest scale, we model the microstructure of polycrystaline materials using a random Voronoï tessellation, each grain being assigned a random orientation. Then, we apply a computational homogenization procedure on statistical volume elements to obtain a stochastic characterization of the elasticity tensor at the second scale of interest, the meso-scale. In the future, using a stochastic finite element method, we will propagate these meso-scale uncertainties to the first resonance frequency at the coarser scale. [less ▲]

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See detailOn the Quality of BGP Route Collectors for iBGP Policy Inference
Cittadini, Luca; Vissicchio, Stefano; Donnet, Benoît ULg

in IFIP Networking (2014, June)

A significant portion of what is known about Internet routing stems out from public BGP datasets. For this reason, numerous research efforts were devoted to (i) assessing the (in)completeness of the ... [more ▼]

A significant portion of what is known about Internet routing stems out from public BGP datasets. For this reason, numerous research efforts were devoted to (i) assessing the (in)completeness of the datasets, (ii) identifying biases in the dataset, and (iii) augmenting data quality by optimally placing new collectors. However, those studies focused on techniques to extract information about the AS-level Internet topology. In this paper, we show that considering different metrics influences the conclusions about biases and collector placement. Namely, we compare AS-level topology discovery with \iac inference. We find that the same datasets exhibit significantly diverse biases for these two metrics. For example, the sensitivity to the number and position of collectors is noticeably different. Moreover, for both metrics, the marginal utility of adding a new collector is strongly localized with respect to the proximity of the collector. Our results suggest that the ``optimal'' position for new collectors can only be defined with respect to a specific metric, hence posing a fundamental trade-off for maximizing the utility of extensions to the BGP data collection infrastructure. [less ▲]

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See detailRole of estradiol in the feminization of lordosis behavior in female mice
Trouillet, Anne-Charlotte ULg

Poster (2014, June)

The classic theory of mammalian brain and behavioral sexual differentiation holds that an organizational action of testosterone, secreted perinatally by the male’s testes, controls male-typical aspects of ... [more ▼]

The classic theory of mammalian brain and behavioral sexual differentiation holds that an organizational action of testosterone, secreted perinatally by the male’s testes, controls male-typical aspects of brain and behavioral development, whereas no active perinatal sex hormone signaling is required for female-typical differentiation. However, it has recently been shown using aromatase knock out (ArKO) mice, which are deprived of estradiol due to a targeted mutation in the aromatase gene, that estradiol may also actively contribute to the differentiation of female-typical aspects of behavior over a specific pre-pubertal period. Female ArKO mice showed significantly lower levels of lordosis behavior than wild type controls following adult ovariectomy and treatment with ovarian hormones. This deficit was restored by treating female ArKO mice with estradiol benzoate between postnatal days 15 and 25. However, the mechanism by which estradiol acts prepubertally in female mice to feminize lordosis behavior remains to be elucidated. Therefore, in a first attempt, we are determining which neuropeptides are in particularly sensitive to estradiol action over the prepubertal period. We will focus on neuropeptides which have been shown to be implicated in lordosis behavior. Studies by the group of Micevych have proposed an important role for NPY and beta-endorphin (B-END) neurons in the arcuate nucleus (ARC) in the estradiol-mediated activation of lordosis behavior in female rats. An in vitro study recently showed that kisspeptin directly activates ARC B-END neurons. This is particularly interesting since unpublished results from our laboratory showed that Kp neurons are directly involved in the expression of lordosis behavior. We are thus currently determining the expression of NPY, B-END, and kisspeptin in the ARC as well as μ-opioid receptors MORs in the MPN over the prepubertal period and their possible modulation by prepubertal estradiol treatment. [less ▲]

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See detailSimple connectome inference from partial correlation statistics in calcium imaging
Sutera, Antonio ULg; Joly, Arnaud ULg; François-Lavet, Vincent ULg et al

in Proceedings of Connectomics 2014 (ECML 2014) (2014, June)

In this work, we propose a simple yet effective solution to the problem of connectome inference in calcium imaging data. The proposed algorithm consists of two steps. First, processing the raw signals to ... [more ▼]

In this work, we propose a simple yet effective solution to the problem of connectome inference in calcium imaging data. The proposed algorithm consists of two steps. First, processing the raw signals to detect neural peak activities. Second, inferring the degree of association between neurons from partial correlation statistics. This paper summarises the methodology that led us to win the Connectomics Challenge, proposes a simplified version of our method, and finally compares our results with respect to other inference methods. [less ▲]

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See detailDistributed Model-free Control of Photovoltaic Units for Mitigating Overvoltages in Low-Voltage Networks
Aristidou, Petros ULg; Olivier, Frédéric ULg; Hervas, Maria Emilia et al

in Proc. of CIRED 2014 workshop (2014, June)

In this paper, a distributed model-free control scheme to mitigate overvoltage problems caused by high photovoltaic generation in low-voltage feeders is proposed. The distributed controllers are ... [more ▼]

In this paper, a distributed model-free control scheme to mitigate overvoltage problems caused by high photovoltaic generation in low-voltage feeders is proposed. The distributed controllers are implemented on the photovoltaic inverters and modulate the active and reactive power injected into the network. In particular, they direct photovoltaic units first to consume reactive power and, if necessary, curtail active power generation to reduce high voltages in the feeder. [less ▲]

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See detailBelowground Chemical Ecology: The Case of Wireworms
Barsics, Fanny ULg; Delory, Benjamin ULg; Delaplace, Pierre ULg et al

Poster (2014, June)

Wireworms, clock-beetles' larvae (Coleoptera, Elateridae), are below ground pests of many crops. They cause dramatic yield losses worldwide. Research on their ecology is crucial to undertake innovative ... [more ▼]

Wireworms, clock-beetles' larvae (Coleoptera, Elateridae), are below ground pests of many crops. They cause dramatic yield losses worldwide. Research on their ecology is crucial to undertake innovative management strategies. In the field of chemical ecology, multitrophic interactions occurring in the rhizosphere are gaining increasing attention from entomologists and agronomists. Our research aims at unveiling the role of volatile organic compounds (VOC) involved in wireworms' foraging behavior, putatively leading to host localization and/or host recognition. [less ▲]

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See detailEstudio ante y postmortem de las caracteristicas fisiopatologicas del tracto genital y sus factores de riesgo en vacas lecheras en el sur de Vietnam
Nguyen, Kien Cuong; Tomas Mulet, Cristina; Okouyi-Mfoumou, Marcel et al

Conference (2014, June)

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See detailExecutive function and grey matter atrophy in healthy aging: A voxel-based morphometry analysis
Manard, Marine ULg; Bahri, Mohamed Ali ULg; Salmon, Eric ULg et al

Poster (2014, June)

Introduction Executive functioning is one of the cognitive domain that declines in healthy aging (Salthouse, Atkinson, & Berish, 2003). In addition, neuroimaging studies pointed out diverse ... [more ▼]

Introduction Executive functioning is one of the cognitive domain that declines in healthy aging (Salthouse, Atkinson, & Berish, 2003). In addition, neuroimaging studies pointed out diverse neurobiological modifications associated to normal aging, such as reduced grey and white matter volumes and cortical thickness (Raz & Rodrigue; 2006). In that context, Voxel Based Morphometry (VBM; Ashburner & Friston, 2000) and Partial Least Square (PLS; McIntoch at al., 1996, 2004) were used to investigate the effect of grey matter atrophy on executive abilities in normal aging. Methods Thirty six young (age range: 18-30) and 43 healthy older (age range: 60-78) adults were included in this study. Executive functioning was assessed by inhibition, updating and shifting tasks (Miyake et al., 2000), and a composite score for general executive ability was created. Structural high resolution T1-weighted images were acquired with a 3T head-only scanner using a standard transmit-receive quadrature head coil (Siemens, Allegra, Erlangen, Germany). The structural images were segmented using VBM8 toolbox, normalized to the MNI stereotaxic space and the resulting grey matter volume images were smoothed (Gaussian kernel: FWHM 8mm). PLS analyses were performed to determine regional grey matter volume differences between young and older adults, and next to identify the regional grey matter volumes specifically associated to executive performance in older participants (p<0.001). PLS is a validated multivariate approach that robustly identifies whole brain activity patterns correlated with behavioral data or experimental design (i.e., scores, conditions or tasks). Results Behavioral data showed a significant age-related decline in executive functioning (t=-5.43; p<.001). MRI analyses showed that significant age-related grey matter volume decrease was mostly observed across a large network including frontal, parietal, and temporal regions. Moreover significant positive correlations between the executive score and the grey matter volumes in older participants were found in a subset of these cortical areas: the inferior, middle and superior frontal cortex, the pre and postcentral gyri, the anterior and middle cingulate cortex, the inferior and superior parietal regions, the retrosplenial cortex, and finally, the inferior, middle and superior temporal regions. Discussion This study first replicated that executive abilities decline with age (Salthouse et al., 2003). This age-related executive decline is related to specific cerebral regions within a large fronto-temporo-parietal network sensitive to age. Interestingly, the areas whose atrophy is linked to executive abilities are quite similar to those evidenced in functional neuroimaging studies in young participants (see Collette & Van der Linden, 2002; Collette, Hogge, Salmon, & Van der Linden, 2006 for reviews). Therefore, using PLS multivariate analyses, we demonstrated that executive changes in normal aging are not dependent on atrophy in frontal areas only but rather comes from a grey matter volume decrease in a large antero-posterior brain network. [less ▲]

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See detailInvestigation of differential virus transmission efficiency in aphid strains: from biological to proteomic assays
Bosquée, Emilie ULg; Francis, Frédéric ULg

Poster (2014, June)

Aphids are well known for their variable efficiency in virus transmission to host plant. Not only aphid species but also aphid strain is an important factor to consider in the plant-aphid-virus ... [more ▼]

Aphids are well known for their variable efficiency in virus transmission to host plant. Not only aphid species but also aphid strain is an important factor to consider in the plant-aphid-virus interactions. In order to investigate these relations, different approaches should be developped from biological observations assessing the virus transmission efficiency to molecular tasks to better know the involved mechanisms in the aphid vector. After a period of virus acquisition on an artificial diet (depending on the kind of transmission, permanent or non permanent ways), the virus transmission rate were assayed and followed by the determination of the presence of virus in the aphid by PCR or immudetection. The aphids were then collected to investigate the variation of aphid proteome and potential involvement in virus interactions. Changes in protein expressions were investigated using a 2D-DIGE approach comparing most and least efficient aphid strains selecting different aphid – virus models (PVY and PLRV in potato, BYDV in wheat, CMV on tobacco) . The proteome changes were analysed using the samespot software. Protein spots with significant up- and down expressions were then mechanically picked, trypsin digested and analysed by Maldi-Tof-Tof. Significantly changed proteins were classify according to metablic pathways and biological functions. Interesting proteins found to probably interact with virus were not only detected from aphid but also from related bacterial symbionts. Theses results were discussed in order to better understand virus – vector relations and potentially promote new ways to control virus transmitted by hemipteran pest. [less ▲]

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See detailPlatelet-rich plasma to treat patellar tendinopathies: a 1 year follow-up.
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in Clinical Chemistry & Laboratory Medicine (2014, June), 52(Special Suppl), 1285

Background: Jumper’s knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

Background: Jumper’s knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. Infiltration of Platelet Rich Plasma (PRP) may be considered as a recent therapeutic option for chronic tendinopathies. The aim of the current study is to evaluate the clinical status and the return to sports activities in patients with chronic upper patellar tendinopathies up to 1 year after 1 infiltration of PRP. Methods: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months and 1 year after the infiltration, using a 10-point Visual Analogic Scale and algofunctional scores (IKDC and VISA-P). Moreover, they had to answer an information questionnaire concerning their life and sports activities. The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub-maximal eccentric reeducation. Results: Pain during daily activities significantly decreased with time. VAS has significantly dropped, IKDC and VISA-P significantly improved over the follow-up of 1 year. Seventy percents of patients reported a favourable evolution with decrease of pain, 15% did never report any improvement and 15% were treated surgically. Seventy percents returned to sports activities, 64,3% without any pain, and 50% of them recovered the same sport level. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. Conclusions: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol can improve, at 1 year, symptoms of chronic jumper’s knee in patients non-responsive to classical conservative treatments. [less ▲]

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See detailEffect of plant defence elicitor on aphid and disease cross infestations
Bosquée, Emilie ULg; Oumarou, Saadatou; Qiu, Dewen et al

Poster (2014, June)

Various bio-aggressors can infest potato plants (Solanum tuberosum L.) throughout its life cycle. In addition to aphids, in particular Myzus persicae Sulzer which transmits Potato virus Y (PVY), plant ... [more ▼]

Various bio-aggressors can infest potato plants (Solanum tuberosum L.) throughout its life cycle. In addition to aphids, in particular Myzus persicae Sulzer which transmits Potato virus Y (PVY), plant pathogenic fungus such as Botrytis cinerea are able to cause damage. To determine the interactions between various bio-aggressors on potato plant defence mechanisms, (1) the effect of an attack by M. persicae followed by an attack by B. cinerea and vice versa, as well as (2) the effect of an elicitor on biological parameters of M. persicae and development of B. cinerea were assessed. On the other hand, (3) the effect of Botrytis cinerea and an elicitor on the efficiency of transmission of PVY by M. persicae was examined. The previous infection by B. cinerea resulted in a significant decrease in growth rate and a sharp reduction of M. persicae fertility, while the infection level of B. cinerea followed by M. persicae infestation was non-significant. Despite a reduction in growth and fertility of M. persicae during the first days of observation, the effect of elicitor on the biological parameters of M. persicae as well as on the development of B. cinerea was non-significant. Regarding the investigations on the PVY transmission by M. persicae, when the elicitor or Botrytis is previously applied on the plant, a significant reduction in the rate of transmission was observed. [less ▲]

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See detailCHARACTERIZATION OF PROTEINURIA IN DOGUE DE BORDEAUX DOGS USING ELECTROPHORESIS AND URINARY BIOMARKERS
Lavoué, Rachel; Smets, P.; Trumel, Cathy et al

in Proceedings of the 2014 ACVIM Forum (2014, June)

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See detailThe Impact of Dual-Tasking on Verbal Short-Term Memory in Children with Specific Language Impairment
Leclercq, Anne-Lise ULg; Maillart, Christelle ULg; Lange, Manon et al

Poster (2014, June)

Limitations in general processing capacities have been proposed to account for poor verbal short-term memory (STM) performances in children with SLI. Previous studies observed that STM performances ... [more ▼]

Limitations in general processing capacities have been proposed to account for poor verbal short-term memory (STM) performances in children with SLI. Previous studies observed that STM performances decreased to a larger extent in children with SLI as compared to their unaffected peers when the processing demands of the task increased (e.g., Ellis Weismer, et al., 2005; Montgomery, 2000a,b). However, in these studies, the increase in attention processing demands went with an increase in linguistic processing demands. Since children with SLI experience language processing problems, it is not clear whether general attention problems or language processing problems are at the root of their larger performance decrease as compared to their unaffected peers. This study aims at directly assessing the hypothesis that limitations in general attentional capacity are at the root of poor STM performances in children with SLI, using an attention demanding visual search task administered concurrently with nonword repetition task. Twenty-three children with SLI, 23 age-matched children, and 23 nonword span-matched children performed immediate serial recall tasks of nonwords. The STM lists were presented either alone or concurrently with the target detection task. Moreover, the target detection task either stopped or continued when children had to recall the nonwords. Results show a main effect of dual task condition on both nonword repetition accuracy and target detection accuracy. Performances in children with SLI were not more affected than in controls by the necessity to perform a concurrent visual attention task during nonword lists presentation. However, nonword recall seemed to be more challenging for children with SLI than for age-matched controls. Indeed, performances in the visual task were lower in children with SLI than in their age-matched controls, but not as compared to nonword span-matched controls. [less ▲]

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See detailMallarmé dans la prison des signes
Durand, Pascal ULg

in Cahiers du CérédI (2014, June), 10

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See detailAnalyse du métier de facilitateur et de son rôle dans la diffusion de normes d’emploi : le cas d’un bureau de chômage belge
Orianne, Jean-François ULg; Beuker, Laura ULg

Conference (2014, June)

En 2004, suite aux injonctions européennes en matière d’activation impulsées par les lignes directrices de 2003-2005, la Belgique met en place le PAC (ou Plan d’Accompagnement des chômeurs). Cette ... [more ▼]

En 2004, suite aux injonctions européennes en matière d’activation impulsées par les lignes directrices de 2003-2005, la Belgique met en place le PAC (ou Plan d’Accompagnement des chômeurs). Cette importante réforme prévoit – notamment – la mise en place de la procédure d’activation du comportement de recherche d’emploi par l’Office National de l’Emploi (Ou l’ONEm). Désormais, des agents sont spécifiquement dédiés à l’évaluation des efforts menés par les demandeurs d’emploi (ou DE) pour s’insérer sur le marché du travail : ce sont les facilitateurs. Si la procédure d’évaluation est officiellement définie, la décision, quant à elle, est bel et bien fonction de l’agent, qui doit interpréter le cadre réglementaire général à l’aune de la situation singulière du demandeur d’emploi. À l’aide d’une étude de cas réalisée au sein d’un bureau de chômage situé en Belgique francophone, nous allons tenter d’ouvrir la « boîte noire » du jugement des facilitateurs. À partir d’une approche qualitative cumulant des entretiens semi-directifs et de l’observation d’interactions entre facilitateurs et demandeurs d’emploi, nous montrerons que la décision des facilitateurs n’est ni arbitraire, ni déterminée. Elle est, au contraire, le fruit de la mobilisation d’une multitude d’appuis conventionnels dans l’action (Dodier, 1993). En outre, dans la lignée des travaux de Benarrosh (2000 ; 2006 ; 2012) nous démontrerons que ces agents sont des « pourvoyeurs » de normes institutionnelles précises à destination des demandeurs d’emploi. [less ▲]

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See detailÉtude des changements de circulation au-dessus de l'océan Austral en été
Belleflamme, Alexandre ULg; Fettweis, Xavier ULg; Erpicum, Michel ULg

in Camberlin, Pierre; Richard, Yves (Eds.) Actes du XXVIIème colloque de l'Association de Climatologie - Climat : système & interactions (2014, June)

Over the five last decades, the reanalyses (ERA and NCEP/NCAR) show a strengthening of the pressure gradient between the southern hemisphere subtropical anticyclone belt and the southern circumpolar lows ... [more ▼]

Over the five last decades, the reanalyses (ERA and NCEP/NCAR) show a strengthening of the pressure gradient between the southern hemisphere subtropical anticyclone belt and the southern circumpolar lows during summer. With the help of an automatic circulation type classification, we show that the strengthening of the pressure gradient is generalised to all circulation types and, paradoxically, it does not cause circulation changes. It is probably implied by the strengthening of the temperature gradient between the tropics and the South Pole, without consequences on the general circulation. Our classification also allows a successful comparison between the two reanalyses in a region where the observation data are rare. [less ▲]

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See detailArrival of european eel in Belgian Part of the Meuse: who and how are they?
Nzau Matondo, Billy ULg; Benitez, Jean-Philippe ULg; Dierckx, Arnaud ULg et al

in Proceedings of the 10th International Conference on Ecohydraulics (2014, June)

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See detailWelcoming the New Gods. Some Reflections on the Interactions between Rulers and Traditional Gods within Ritual Practice
Paul, Stéphanie ULg

Conference (2014, June)

One of the major changes identified as characteristic of Hellenistic religion is the introduction of new cults, and notably cultic honours for mortal rulers. Hellenistic poleis displayed various ... [more ▼]

One of the major changes identified as characteristic of Hellenistic religion is the introduction of new cults, and notably cultic honours for mortal rulers. Hellenistic poleis displayed various expedients to integrate these newcomers within their civic and religious landscape, operating a balanced dialectic between innovation and tradition. This integration happened at several levels, whether from a topographic point of view - e.g. consecration of a temenos, installation of altars, statues in sanctuaries of other gods (Schmidt-Dounas 1995) - or through ritual practice - e.g. the foundation of sacrifices and festivals, that were sometimes “appended” to a pre-existing festival (Buraselis 2012). The decree from Teos founding the cult of Antiochos III and Laodike exemplifies with great detail how a ruler cult could be integrated within a civic pantheon and how it echoed other cults (Chaniotis 2007). Based on a few selected inscriptions, this paper will explore some interactions between rulers and local gods as noted in ritual practice. A newly-published inscription from Aigai in Aiolis (EA 42 [2009], 32-60), regulating the foundation of honours for Seleukos I and Antiochos I after their victory over Lysimachos in 281 BC, exemplifies some of these interactions. The decree refers explicitly to Apollo, one of the main god of Aigai, regarding both the localization of the temenos of the kings next to the sanctuary of the god, and also sacrificial regulations, which were modelled after the sacrifices to Apollo. Other cultic associations with a goddess named Sôteira and Zeus Sôter echoed the epithet given to the kings and emphasised the circumstances that led to the introduction of their cult. Further lines of enquiry include the associations with traditional gods of the civic pantheon in prayers and sacrifices that are performed in honour of the king, thus placing the latter in an intermediary position between the polis and the gods. This is the case of an inscription from Ilion (I.Ilion 32), associating a king Antiochos with Athena Ilias on the one hand, Apollo, Zeus and Nike on the other hand, in a dialectic similar to the one observed at Aigai. Although the nature of ritual performance is not very informative as regards the specificity of ruler cult – in so far as it little differed from traditional rituals (Wikander 2005) – the interactions with the gods of the civic pantheon within ritual practice is nonetheless interesting to explore from the point of view of the integration of these new cults. Indeed, although the “practicalities of ruler cult” are not per se very specific, the mechanisms put in place by the poleis may differ in so far as they correspond to a local, specific, context. [less ▲]

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See detailGeometric parameters influence on Piano Key Weir hydraulic performances
Erpicum, Sébastien ULg; Archambeau, Pierre ULg; Pirotton, Michel ULg et al

in Chanson, Hubert; Toombes, Luke (Eds.) Hydraulic Structures and Society – Engineering Challenges (2014, June)

The Piano Key Weir is a recent evolution of the traditional labyrinth weir. Thanks to a reduced foot print, this nonlinear weir can be placed on the top of gravity dams. The Piano Key Weir geometry ... [more ▼]

The Piano Key Weir is a recent evolution of the traditional labyrinth weir. Thanks to a reduced foot print, this nonlinear weir can be placed on the top of gravity dams. The Piano Key Weir geometry involves a large number of geometric parameters. Several experimental studies have been carried out to investigate the main geometric parameters influencing the weir hydraulic efficiency and to define their optimal value. In this paper, the experimental data gathered at the University of Liege are re-examined to show how the weir height, the keys widths and the overhangs positions influence, for a given crest length magnification ratio, the weir discharge capacity. The theoretical rating curve of a standard linear weir is considered for comparison. The analysis highlights that the keys widths and overhangs lengths ratios influence significantly the Piano Key Weir efficiency, but less than the weir height. Considering the above mentioned results, a cost efficient design proposed in the literature is also proved to be close to the hydraulic optimum. [less ▲]

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See detailLe ciel étoilé d’Isis et d’Héphaïstos à Memphis
Veymiers, Richard ULg

Conference (2014, June)

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See detailThe X-ray properties of lambda Cep, a true twin of zeta Pup?
Rauw, Grégor ULg; Nazé, Yaël ULg; Gonzalez-Perez, Nicolas et al

Conference (2014, June)

Oef stars are O-stars that display a double-peaked He II λ 4686 line in their optical spectra, suggesting that the inner part of the stellar wind is co-rotating with the star. This hypothesis is also ... [more ▼]

Oef stars are O-stars that display a double-peaked He II λ 4686 line in their optical spectra, suggesting that the inner part of the stellar wind is co-rotating with the star. This hypothesis is also often used to explain their ubiquitous spectral variability in the optical domain. In this context, the fact that the high-resolution X-ray spectra of ζ Pup (O4Ief) meet the expectations of the wind-embedded shock model, assuming a spherically symmetric wind came as a surprise. To understand what is going on, we have obtained a 300 ksec observation of λ Cephei, the second brightest Oef star. This observation not only allows to collect the RGS high-resolution spectrum of the star, but further enables us to search for X-ray variability. To correlate the potential X-ray variability with that of the optical spectrum of λ Cep, we monitored the optical spectrum simultaneously with the TIGRE telescope. We present here the first results of this campaign, both in terms of the line profiles in the RGS spectrum and the search for X-ray variability in correlation with the optical variations. [less ▲]

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See detailLe B.I.M et la maquette virtuelle comme moyen pédagogique permettant le rapprochement entre les cours d'informatique et l'enseignement du projet d'architecture
Boutemadja, Abdelkader ULg; Driesmans, Carine ULg; Jancart, Sylvie ULg

in Kubicki, Sylvain; Halin, Gilles; Bignon, Jean-Claude (Eds.) Scan 14 sémainaire de conception architecturale numérique : Interaction(s) des maquettes numériques (2014, June)

In the context of this paper, we pose the question of the conditions of possible link between computer courses and design projet. The integration of schools of architecture at universities is an ... [more ▼]

In the context of this paper, we pose the question of the conditions of possible link between computer courses and design projet. The integration of schools of architecture at universities is an opportunity to focus in the experiments made in this direction and to propose to implement the terms of this rapprochement. For us, it is important that this approach lies in the Bachelor years in a common core for all students. [less ▲]

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See detailThe grassland model intercomparison of the MACSUR (Modelling European Agriculture with Climate Change for Food Security) European knowledge hub
Ma, Shaoxiu; Acutis, Marco; Barcza, Zoltan et al

in Proceedings of the 7th International Congress on Environmental Modelling and Software (iEMSs) June 15-19, 2014, San Diego, California, USA (2014, June)

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See detailSTUDIO in vitro DEI PARAMETRI DI COINFEZIONE E SUPERINFEZIONE CHE INFLUENZANO LA RICOMBINAZIONE NEI NOROVIRUS
Di Felice, Elisabetta; Ceci, Chiara; Zonta, William ULg et al

Poster (2014, June)

I norovirus (NoV) sono piccoli virus (38-40 nm) a RNA monocatenario sprovvisti di envelope appartenenti alla famiglia Caliciviridae. I NoV attualmente vengono riconosciuti come una delle più importanti ... [more ▼]

I norovirus (NoV) sono piccoli virus (38-40 nm) a RNA monocatenario sprovvisti di envelope appartenenti alla famiglia Caliciviridae. I NoV attualmente vengono riconosciuti come una delle più importanti cause di gastroenterite acute di origine non batterica nell'uomo coinvolgendo tutte le classi di età e soprattutto contesti comunitari. I meccanismi molecolari che influenzano l'evoluzione dei NoV sono l'accumulo di mutazioni puntiformi e la ricombinazione. L’obiettivo sarà quello di dimostrare che la ricombinazione è un evento che può essere influenzabile dall’impiego di diversi parametri di coinfezione/superinfezione. In letteratura, gli studi sugli eventi ricombinanti che caratterizzano i NoV umani risultano piuttosto limitati a causa dell'assenza di un substrato cellulare che ne permetta la replicazione in vitro. Nel presente lavoro è stato sviluppato un modello sperimentale basato sull’impiego dell’unico NoV, il norovirus murino (MNV), in grado di replicare su substrato cellulare. A tal fine monostrati di cellule RAW264.7 sono stati coinfettati e superinfettati con due ceppi di MNV (CW1 e WU20) utilizzando diversi indici di molteplicità (MOI) e differenti tempi di infezione. I surnatanti sono stati collezionati a 24 e 48 ore post-infezione e quindi sottoposti a metodo delle placche. All’interno della popolazione virale risultante da tale coinfezione/superinfezione, 36 cloni per ciascuna condizione sono stati selezionati e purificati dalle placche e, successivamente, utilizzati per infettare nuovi monostrati cellulari di RAW264.7. Il monitoraggio degli eventi ricombinanti è stato eseguito mediante PCR e Real-Time PCR dopo estrazione dell'RNA virale e retrotrascrizione, impiegando due set di primer in grado di amplificare le regioni site all’estremità iniziale di ORF1 e all’estremità terminale di ORF3. I risultati che permetteranno di quantificare la distribuzione dei ceppi presenti nel surnatante della superinfezione, sono ancora in corso di analisi. [less ▲]

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See detailInhibition of PDH Kinase as a new therapeutic target for Age-related Macular Degeneration (AMD)
Arslan, Deniz ULg; Pirotte, Bernard ULg; De Tullio, Pascal ULg et al

Poster (2014, June)

Metabolomics is one of the most recent technologies in the world of Omics sciences. It aims at studying metabolome, which is composed of small molecular weight organic molecules (called metabolites) of a ... [more ▼]

Metabolomics is one of the most recent technologies in the world of Omics sciences. It aims at studying metabolome, which is composed of small molecular weight organic molecules (called metabolites) of a cell, an organism or a biological system. This approach gives rise to a growing number of applications in many areas, such as biomarkers discovery, clinical studies, drug efficacy and toxicity evaluation, diagnostic tools, quality control. One of the most interesting features of metabolomics is its capability to extract biochemical information reflecting biological events and then to be a powerful tool in the knowledge of the aetiology of some pathologies. Indeed, it is clear that every disease could alter more or less drastically the metabolic profile of the patients. Then a metabolomics approach could highlight the biochemical pathways affected and could allow the identification of new putative therapeutic strategies or targets that could be useful in a new drug discovery strategy. As proteomics, metabolomics approach represents a new and powerful tool for Medicinal Chemistry. Age-related Macular Degeneration (AMD) is a leading cause of vision loss in the western world among people aged 50 or older. 90% of all vision loss due to AMD results from the exudative form, which is characterized by choroidal neovascularization (CNV). Age-related changes that induce pathologic CNV are incompletely understood. A successful application of anti-VEGF approaches in the clinic is obviously a turning point in AMD treatment. Nevertheless, despite such important advances, critical issues remain to be addressed. To better understand the aetiology of this pathology, we used and improved a murine model of laser-induced choroidal neovascularization and applied a 1H NMR metabolomics study. This approach leads to the emergence of different putative biomarkers and to the validation of the CNV model for an experimental study of AMD. Among these “biomarkers”, lactate appears to be clearly involved in the development of AMD. The modulation of their plasma concentration by treatment of the animals with synthetic compounds and more specifically Pyruvate DesHydrogenase Kinase inhibitors (PDHK) significantly decrease the impact of laser induced CNV. Starting from these results, the development of new PDHK inhibitors could open the way to innovative treatment opportunities in AMD disease. [less ▲]

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See detailEvaluation of troponin T on AQT90 Flex and COBAS 8000 as a rule in/out tool in an emergency ward
LE GOFF, Caroline ULg; EVRARD, Séverine ULg; BREVERS, Eric ULg et al

in Clinical Chemistry & Laboratory Medicine (2014, June), 52(Special Suppl), 510

BACKGROUND: Troponin measurement is the gold standard for diagnosis of Acute Myocardial Infarction (AMI). Troponin (highly sensitive (hs), T or I) is measured by immunochemistry instrument or by Point of ... [more ▼]

BACKGROUND: Troponin measurement is the gold standard for diagnosis of Acute Myocardial Infarction (AMI). Troponin (highly sensitive (hs), T or I) is measured by immunochemistry instrument or by Point of Care (POCT). POCT can be useful in emergency lab or ward for a faster diagnosis of patients with chest pain. Our study compared analytical performance of a POCT AQT90 Flex (Radiometer Medical) (AQT) and TnThs Cobas 8000 (Roche Diagnostics) (Cobas). We also compared the clinical performance of both methods at recommended cut-off (14 ng/L for Cobas and 30 ng/ L for AQT). METHODS: We selected 104 patients (296 samples) (range: 6-13822 ng/L) admitted in the Emergency ward for which at least 1 troponin determination (Cobas 8000) had been re-quested in the past 24 hours according to rule in/out procedure applied by this ward. Samples were then measured with the AQT. Inter-assay CV was maximum 8.6% and 9.6% for Cobas and AQT respectively. The cut-off defined as the 99th percentile for Roche was 14 ng/L and the recommended decision threshold value was 30 ng/L for Radiometer. Retrospective analysis of final diagnostic was obtained for all participants: we considered as “true positive” patients for whom a final diagnostic was ST segment-Elevation Myocardial Infarction (STEMI) or non STEMI (NSTEMI). RESULTS: On the whole range of measure, the 2 methods showed a good correlation (r2=0.98). Regression equation was Cobas = 0.98 AQT + 31 ng/L (95%CI of the intercept: (26.7;37.7) and 95% CI of the slope (0.96;1)). When we stratified, for the values <54 ng/L, the equation became Cobas = 0.52 AQT +1.1 ng/L (95%CI of the intercept: (-4.8;5.5) and 95% CI of the slope (0.39;0.69)). Bland and Altman plot did not show any bias. At admission [2-7 hours], 78 (81%) of admitted patients were finally considered as AMI, sensitivity was 92 % [96%] for Cobas and 78% [91%] for AQT. Specificity was 15% for Cobas (cut-off 14ng/L) or 73% (cut-off 54 ng/L) and 76% for AQT. CONCLUSIONS: Overall, there was a good correlation between the 2 methods. However, using a cut-off of 14 ng/L for Cobas is questionable for a rule in/out procedure in an emergency ward. Using 54 ng/L for Roche and 30 ng/L for AQT would have led to the best discrimination between patients presenting AMI or not. [less ▲]

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See detailResearch of phosphate accumulating microorganisms from WWTPs for the recovery of phosphorus from organic wastes (3BV.3.47)
Tarayre, Cédric ULg; Michels, Evi; Buysse, Jeroen et al

Poster (2014, June)

Many wastes containing reusable components, such as nitrogen, phosphorus and potassium, are not exploited through ideal processes. As an example, in Wallonia (Belgium), the main treatment applied to ... [more ▼]

Many wastes containing reusable components, such as nitrogen, phosphorus and potassium, are not exploited through ideal processes. As an example, in Wallonia (Belgium), the main treatment applied to sewage sludge consists in incinerating the material. Such a process is chosen when the heavy metals are too concentrated in the sludge, preventing an agricultural use. However, sewage sludge, as well as manure, slurry and digestate, contain notable amounts of nutrients (nitrogen, phosphorus and potassium). Some Waste Water Treatment Plants (WWTPs) are actually designed in order to promote Phosphate Accumulating Organisms (PAOs), able to store or release phosphorus in accordance with the environmental conditions. The aim of this work is to isolate PAOs from WWTPs and evaluate their applicability to phosphorus recovery from organic wastes. Metagenomics and metabolic properties are also considered. This work is supported by the BioRefine Project, a European project in which various member states focus on recovery of inorganics from organic wastestreams. [less ▲]

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See detailRepresentations of Incident Reporting as a Collective Learning Process
Rossignol, Nicolas ULg; Turcanu, Catrinel

Conference (2014, June)

In the context of vulnerability analysis, it is now widely aknowledged that social factors should be taken into account, alongside technical ones. Depending on the particular approach adopted, these ... [more ▼]

In the context of vulnerability analysis, it is now widely aknowledged that social factors should be taken into account, alongside technical ones. Depending on the particular approach adopted, these social factors are considered to influence “coping capacities”, “adaptive capacities” or “resilience”. The ability of a socio-technical system to learn from past incidents and accidents seems to have a positive influence on its vulnerability, as it increases its capacity to adapt properly in case of future unwanted envents. To that regard, incident reporting systems are of first importance as they are supposed to constitute a collective memory of past incidents, to initiate a collective share of information and to foster collective learning and adapations. Yet, the theoretical assumptions about the ability of a reporting system to imply collective learning have still to be demonstrated. This paper proposes a methodology addressing this issue. To do so, we conduct a number of semi-structured interviews in a nuclear facility with various types of actors (managers, lab responsibles, technical workers), and in different risk contexts. In addition, participants are requested to produce a mental map of the reporting system they are concerned with. These inputs are then analyzed following a “cross-case analysis” procedure in order to identify patterns of actors' representations of the reporting system, and to link these patterns to potential learning processes fostered by the system. This constitutes the first step of an inductive research process aiming to identify and characterize the link between reporting systems and collective learning. In the next steps, the link between the identified patterns of representations and collective learning processes will be tested quantitatively. The final aim being to elaborate ways to improve Incident Reporting Systems to improve collective learning. [less ▲]

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See detailProduction, Private Economy and State Entanglement in Early Northern Mesopotamia
Mas, Juliette ULg

Conference (2014, June)

Ancient economic systems from Southern and Central Mesopotamia are quite well known when Northern Mesopotamia ones remain less known from this point of view. If we already know that, during Bronze Age ... [more ▼]

Ancient economic systems from Southern and Central Mesopotamia are quite well known when Northern Mesopotamia ones remain less known from this point of view. If we already know that, during Bronze Age, households played a deciding role in several kinds of production, their degree of dependence or independence to the State still has to be cleared. The archaeological data clearly show that private workshops, set up in private houses, could be very efficient and specialized. Furthermore, these economic entities could be assimilated to private enterprises, which were able to handle their own administrative duties. On the other hand, we know from the texts that the Palace and the temples were also a main element of ancient economic systems. If public administrations should, in some cases, have supplied raw materials, hired workforce, and dealt with the distribution of produced goods, it seems that the production didn’t take place in the palace itself. Dealing both with archaeological and textual data, could help to better define the role and the importance of both public and private components in early Mesopotamian economic systems. [less ▲]

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See detailBayes Adaptive Reinforcement Learning versus Off-line Prior-based Policy Search: an Empirical Comparison
Castronovo, Michaël ULg; Ernst, Damien ULg; Fonteneau, Raphaël ULg

in Proceedings of the 23rd annual machine learning conference of Belgium and the Netherlands (BENELEARN 2014) (2014, June)

This paper addresses the problem of decision making in unknown finite Markov decision processes (MDPs). The uncertainty about the MDPs is modeled using a prior distribution over a set of candidate MDPs ... [more ▼]

This paper addresses the problem of decision making in unknown finite Markov decision processes (MDPs). The uncertainty about the MDPs is modeled using a prior distribution over a set of candidate MDPs. The performance criterion is the expected sum of discounted rewards collected over an infinite length trajectory. Time constraints are defined as follows: (i) an off-line phase with a given time budget can be used to exploit the prior distribution and (ii) at every time step of the on-line phase, decisions have to be computed within a given time budget. In this setting, we compare two decision-making strategies: OPPS, a recently proposed meta-learning scheme which mainly exploits the off-line phase to perform policy search and BAMCP, a state-of-the-art model-based Bayesian reinforcement learning algorithm, which mainly exploits the on-line time budget. We empirically compare these approaches in a real Bayesian setting by computing their performances over a large set of problems. To the best of our knowledge, it is the first time that this is done in the reinforcement learning literature. Several settings are considered by varying the prior distribution and the distribution from which test problems are drawn. The main finding of these experiments is that there may be a significant benefit of having an off-line prior-based optimization phase in the case of informative and accurate priors, especially when on-line time constraints are tight. [less ▲]

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See detailAn Investigation into the Influence of External Walls Reflectivity on the Indoor Daylight Availability in Desert Climates
Hegazy, Mohamed Amer; Attia, Shady ULg

in Conference Proceedings: Building Simulation and Optimization 2014 (2014, June)

Hot arid climates are characterized by clear sunny sky most of the year time. Such climates affects the urban morphology, which requires sometimes dense urban fabric. Narrow streets have significant ... [more ▼]

Hot arid climates are characterized by clear sunny sky most of the year time. Such climates affects the urban morphology, which requires sometimes dense urban fabric. Narrow streets have significant effect on the amount of daylight permeating indoor residential zones, which may have a negative or positive effect on the overall visual performance. This paper studies the quantitative effect of using different Façade reflectivity ratios, under different street widths, on the indoor daylight autonomy. The researcher performed a parametric analysis using DIVA for Rhino simulation tool on a hypothetical residential building unit with various window ratios facing neighbouring buildings. Four main orientations were examined under different urban contexts and wall reflectivity. This paper aims to measure daylight autonomy and address possible strategies and solutions to achieve better daylighting that can be used by architects at early design stages of housing developments in the desert climates. [less ▲]

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See detailBacteria, bonds between classical karsts and karsts in silicated non carbonated rocks ?
Willems, Luc ULg

Poster (2014, June)

For several years, similar karsts to those found in the limestone have been observed in various silicated non-carbonated rocks. Several morphological arguments show that a complete dissolution of rocks is ... [more ▼]

For several years, similar karsts to those found in the limestone have been observed in various silicated non-carbonated rocks. Several morphological arguments show that a complete dissolution of rocks is necessary to explain the formation of some caves and other related forms independently of hydrotermalisme phenomena. However, the physico-chemical processes generally considered do not provide a satisfactory explanation to this dissolution. Bacterial activity found deep in many lithologies provides a solution to this apparent contradiction. [less ▲]

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See detailSUITABILITY OF 24,25(OH)2 VITAMIN D3 DETERMINATION WITH AN ADAPTED VERSION OF THE CHROMSYSTEMS® MASSCHROM® 25-OH-VITAMIN D3/D2– LC-MS/MS KIT
SCHLECK, Marie-Louise ULg; NETCHACOVITCH, Matthieu ULg; CRINE, Yannick ULg et al

in Clinical Chemistry & Laboratory Medicine (2014, June), 52(Special Suppl), 1235

BACKGROUND: The enzym CYP24A1 catalyses the conversion of 25(OH)D3 in 24,25(OH)2D3. Recently, loss-of-function mutation of CYP24A1 has been identified in idiopathic infantile hypercalcemia (IIH). This ... [more ▼]

BACKGROUND: The enzym CYP24A1 catalyses the conversion of 25(OH)D3 in 24,25(OH)2D3. Recently, loss-of-function mutation of CYP24A1 has been identified in idiopathic infantile hypercalcemia (IIH). This genetic defect can be highlighted by high 1,25(OH)2D3 and undetectable 24,25(OH)2D3 levels. 24,25(OH)2D3 is also known to interfere with 25(OH)D3 determinations with immunoassays, leading to an overestimation of the 25(OH)D3 concentrations. We adapted the MassChrom kit on the AB SCIEX TQ 5500 in order to systematically provide, next to 25(OH)D3, 25(OH)D2 and C3 epimer, the concentrations of 24,25(OH)2D3. The aim of this study was to evaluate the performance of 24,25(OH)2D3 determination with this modified method. We also wanted to establish the reference value of 24,25(OH)2D3. METHODS: We modified the Chromsystems MassChrom method by adding the 24,25(OH)D3 correspondent transitions and performed a calibration by spiking known amounts of 24.25(OH)2D3. The LOQ was determined with 10 concentration levels of 24,25(OH)2D3. We selected 92 healthy children (40 girls; 2.4±1.51 years) presenting normal calcium levels (2.49±0.13mmol/l) to determine the 95th percentile (p95). RESULTS: The 24,25(OH)2D3 LOQ was 4.7 ng/ml. 85.9% of our subjects were below this LOQ. The p 95 for the 24,25(OH)2D3, according to the CLSI C28-A3, was <6.2 ng/ml. The average serum concentrations (mean±SD) of 25(OH)D3 and 3-epi-25(OH)D3 were 24.48±10.22ng/ml and 2.07±1.86 ng/ml respectively. The 24,25(OH)2D3 levels (r2=0.64) correlated with the 25(OH)D3 levels. CONCLUSIONS: Our adapted method from Chromsystems Vitamin D determination is available to quantify 24,25(OH)2D3. In this context, this method is able to determine high levels of 24,25(OH)2D3 that can possibly cross react with immunoassays. However, as the LOQ was not low enough, we couldn’t establish correct reference value for 24,25(OH)2D3. A derivatization step in the sample preparation would be interesting to improve the sensibility of the method. [less ▲]

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See detailReceptor expression in craniopharyngiomas causing tumor growth in pregnancy: case report and review of the literature
VROONEN, Laurent ULg; TOME, Monica; THIRY, Albert ULg et al

in Abstract book : 57èmes Journées Internationales d'Endocrinologie Clinique - Henri-Pierre Klotz (2014, June)

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See detailThe Call for project proposals « Let’s live my village »: between free interpretations and compulsory readings regarding innovation and convivial village ambiance in Wallonia.
Schmitz, Serge ULg

in Les campagnes: espaces d'innovation dans un monde urbain (2014, June)

The paper scrutinizes 186 rural development projects selected on the short list of the first and second “Lets’ live my village!” calls. It examines trends concerning rural community life and the identity ... [more ▼]

The paper scrutinizes 186 rural development projects selected on the short list of the first and second “Lets’ live my village!” calls. It examines trends concerning rural community life and the identity of the leaders/brokers. It pays attention to the way that associations define rurality. Question 14 of the application form « Does your association act in rural areas? Explain” is the main source of information for content analysis and contingency tables [less ▲]

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See detailModeling of the Iturinic Antimicrobial Lipopeptide Mycosubtilin at Interfaces
Loison, Claire; Nasir, Mehmet Nail ULg; Benichou, Emmanuel et al

Conference (2014, June)

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See detailThe X-ray emission of the massive stars population in Cyg OB2
Rauw, Grégor ULg; Nazé, Yaël ULg; Wright, Nick et al

Poster (2014, June)

Cygnus OB2 contains a wealth of massive stars of spectral types O, B and Wolf-Rayet. In the framework of a Chandra legacy program to study the X-ray emission from this important association, we have ... [more ▼]

Cygnus OB2 contains a wealth of massive stars of spectral types O, B and Wolf-Rayet. In the framework of a Chandra legacy program to study the X-ray emission from this important association, we have studied the X-ray properties of its massive stars population. We show that the O-stars in Cyg OB2 follow a well-defined scaling relation between their X-ray and bolometric luminosities: log(Lx/Lbol) = −7.2 ± 0.2. Except for the brightest O-star binaries, there is no general X-ray overluminosity due to colliding winds in O-star binaries. Roughly half of the known B-stars in the surveyed field are detected, but they fail to display a clear relationship between Lx and Lbol. Out of the three WR stars in Cyg OB2, probably only WR144 is itself responsible for the observed level of X-ray emission, at a very low log(Lx/Lbol) = −8.8±0.2. The X-ray emission of the other two WR-stars (WR145 and 146) is most probably due to their O-type companion along with a moderate contribution from a wind-wind interaction zone. [less ▲]

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See detailMembrane interactions of cyclic lipodepsipeptides from the viscosin group
Geudens, Niels; Feher, Krisztina; De Vleeschouwer et al

Poster (2014, June)

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See detailOn the Performance of the LISP Beta Network
Coras, Florin; Saucez, Damien; Iannone, Luigi et al

in IFIP Networking (2014, June)

The future Internet has been a hot topic during the past decade and many approaches towards this future Internet, ranging from incremental evolution to complete clean slate ones, have been proposed. One ... [more ▼]

The future Internet has been a hot topic during the past decade and many approaches towards this future Internet, ranging from incremental evolution to complete clean slate ones, have been proposed. One of the proposition, LISP, advocates for the separation of the identifier and the locator roles of IP addresses to reduce BGP churn and BGP table size. Up to now, however, most studies concerning LISP have been theoretical and, in fact, little is known about the actual LISP deployment performance. In this paper, we fill this gap through measurement campaigns carried out on the LISP Beta Network. More precisely, we evaluate the performance of the two key components of the infrastructure: the control plane (i.e., the mapping system) and the interworking mechanism (i.e., communication between LISP and non-LISP sites). Our measurements highlight that performance offered by the LISP interworking infrastructure is strongly dependent on BGP routing policies. If we exclude misconfigured nodes, the mapping system typically provides reliable performance and relatively low median mapping resolution delays. Although the bias is not very important, control plane performance favors USA sites as a result of its larger LISP user base but also because European infrastructure appears to be less reliable. [less ▲]

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See detailSorting of crop residues and fossil bones from soil by NIR Hyperspectral Imaging
Vincke, Damien; Eylenbosch, Damien ULg; Fernández Pierna, Juan Antonio et al

Conference (2014, June)

The scope of this paper is to present two applications using Near Infrared Hyperspectral Imaging (NIR-HSI) combined with chemometrics to sort constituents of soil and assess their qualitative parameters ... [more ▼]

The scope of this paper is to present two applications using Near Infrared Hyperspectral Imaging (NIR-HSI) combined with chemometrics to sort constituents of soil and assess their qualitative parameters. In the first application, the feasibility of using NIR-HSI to sort crop residues such as roots and straws in soil has been demonstrated. In the second application the potential of such instrumentation and method to assess the level of collagen preservation in fossil bones has been proved. [less ▲]

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See detailEffect of task demands on phonological acquisition : the acquisition of phonemes in French speaking children aged 30 to 53 months in four different contexts.
Maillart, Christelle ULg; Vaucel, Cécile; Macleod, Andrea

Poster (2014, June)

When children first begin to produce the phonemes of their language, their productions are characterized by a high degree of variability (e.g., Ferguson & Farwell, 1975) and are influenced by task demands ... [more ▼]

When children first begin to produce the phonemes of their language, their productions are characterized by a high degree of variability (e.g., Ferguson & Farwell, 1975) and are influenced by task demands (Khami, Catts, & Davis, 1984). As children’s phonological representations become more defined, their productions become more stable and less influenced by the task demands. Despite the clinical significance of phonological variability, there exists no normative data that can be used to objectively describe this variability in French. The goal of the present study was to describe variability and consistency among French-speaking children between the ages of 30 and 53 months, according to task demands. A total of 153 children participated in the present study and were equally distributed in four groups (aged 30-35, 36-41, 42-47, and 48-53 months). We created a picture identification task with 65 target words, which contained the consonants of French in word initial, medial and final position. The children were asked to produce these words in four different contexts : 1) picture naming ; 2) word repetition ; 3) sentence repetition ; 4) spontaneous language. Two measures of consistency were used. (1) A consonant level analysis that investigated the stability of phonological accuracy. (2) A word level analysis that investigated the consistency of productions across the four tasks. We predict that younger children will be more influenced by changes in task complexity than older children. [less ▲]

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See detailEstimated Subglottic Pressure Evaluation According to Vocal Pathology. Study on 418 Patients
Morsomme, Dominique ULg; Chareix, Hélène; FINCK, Camille ULg et al

Conference (2014, May 31)

Estimated subglottic pressure (ESGP) is part of the aerodynamic measurements included in the vocal profile. It is an indication of vocal effort and can guide the therapist in his clinical approach. We aim ... [more ▼]

Estimated subglottic pressure (ESGP) is part of the aerodynamic measurements included in the vocal profile. It is an indication of vocal effort and can guide the therapist in his clinical approach. We aim to examine the clinical interest of the ESGP by observing its values according to voice pathology, age, gender and sound pressure level. We also examine the relationships between PSGE, DSI and VHI. Method:The study includes 418 patients (M:118/W:300). Each patient’s file consists of VLS, acoustic, aerodynamic and perceptual measures. The ESGP was collected through the Phonatory Aerodynamic System Model 6600 (KayPentax). Patients produced 3 sequences of / ipipi / at low (IL), conversational (IC) and high (IH) intensity. Patients were grouped according to the ENT’s diagnosis. Results: Patients without vocal lesions (MTD) had a significantly lower ESGP compared to patients with nodules, polyps, inflammation, edema (IL, IC), cysts (IC) or scar (IC). Patients with vocal fold atrophy had a lower ESGP than those suffering from nodules and polyps at conversational and high intensity, but were not differentiated at low intensity. Amongst patients without lesions (MTD), a positive correlation appeared between ESGP and intensity; which was not the case for patients with lesions. At high intensity, men had a significantly higher ESGP than women. At low intensity, we noted a positive correlation between the VHI scores and ESGP levels. At low and conversational intensity, we observed a negative correlation between DSI and ESGP scores. Conclusion: This study highlights the importance of considering ESGP in the vocal profile. As expected, patients with vocal pathology produce high ESGP. However, the correlations between intensity and ESGP vary depending on the patient's pathology. In addition, ESPG values allow the clinician to distinguish MTD and healthy patients and thus could help the therapist in his clinical approach. [less ▲]

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See detailBoard attributes and conditional conservatism: Evidence from French firms
Boussaid, Nabila ULg; Sougné, Danielle ULg; Hamza, Taher

Conference (2014, May 30)

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See detailUsing shear strain localisation to model the fracturing around gallery in unsaturated Callovo-Oxfordian claystone
Pardoen, Benoît ULg; Levasseur, Séverine ULg; Collin, Frédéric ULg

in 10th International Workshop on Bifurcation and Degradation in Geomaterials (2014, May 30)

Galleries drilling leads to damage propagation, fracturing and properties modifications in the surrounding medium. The prediction of the damaged zone behaviour is an important matter and needs to be ... [more ▼]

Galleries drilling leads to damage propagation, fracturing and properties modifications in the surrounding medium. The prediction of the damaged zone behaviour is an important matter and needs to be properly assessed. To do so the fractures can be modelled using shear strain localisation. The coupled local second gradient model is used under unsaturated conditions to correctly model the strain localisation behaviour. The permeability evolution and the rock desaturation due to air ventilation in galleries are considered. Finally, a hydro-mechanical modelling of a gallery excavation in Callovo-Oxfordian claystone is performed leading to a fairly good representation of the damaged zone. [less ▲]

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See detailWind Tunnel Testing of a VTOL MAV Propeller in Tilted Operating Mode
Theys, Bart; Dimitriadis, Grigorios ULg; Andrianne, Thomas ULg et al

in Proceedings of the 2014 International Conference on Unmanned Aircraft Systems (ICUAS 2014) (2014, May 30)

This paper presents experimental results of the full 3-axis force vector and 3-axis moment vector acting on a propeller, commonly used for a Vertical Take Off and Landing Micro Aerial Vehicle (VTOL MAV ... [more ▼]

This paper presents experimental results of the full 3-axis force vector and 3-axis moment vector acting on a propeller, commonly used for a Vertical Take Off and Landing Micro Aerial Vehicle (VTOL MAV). Measurements were carried out in a wind tunnel using a high resolution 6-axis force/moment sensor embedded in a customized test rig at several wind speeds, propeller rotational speeds and angles of the propeller shaft with respect to the air stream. Results show strong moments acting on the propeller in forward flight and unstable conditions in descending flight. Power calculations reveal a decrease in power consumption during slow forward flight and how motor efficiency can be maximized. [less ▲]

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See detailNumerical Investigation of Continuous Fiber Glass Drawing Process
Chouffart, Quentin ULg; Simon, Philippe; Terrapon, Vincent ULg

Conference (2014, May 30)

The manufacturing process of glass fibers used for the reinforcement of composite material consists in drawing a glass melt at high temperature through the bushing plate into fibers using a winder. This ... [more ▼]

The manufacturing process of glass fibers used for the reinforcement of composite material consists in drawing a glass melt at high temperature through the bushing plate into fibers using a winder. This process is sensitive to numerous disturbances that can cause the fiber to break during the drawing process. In order to understand the origin of these failures and improve the process efficiency, it is important to understand the physics of the forming fiber. We investigate here the underlying physics of the forming of a single fiber through numerical simulations. In particular, we focus on the region from the hole tips at the bushing plate to the glass transition point. The influence of key parameters (e.g. operating windows, and heat transfers mechanisms) on the fiber radius attenuation and the internal stresses is investigated through a sensitivity analysis. In addition, the impact of the temperature variations at the bushing plate is investigated. Finally, we show how the forming stress is influenced by these parameters. It is found that the internal stress can be minimizing by varying the operating windows. On the other hand, results also demonstrate that the heat pattern of the bushing plate is one of the most important causes for disturbance in the process. [less ▲]

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See detailToward a Characterization of Western Operatic Singing Voices
Larrouy, Pauline ULg; Magis, David ULg; Nowak, Marion et al

Poster (2014, May 29)

Objective: One can easily recognize the musical style of a singer by listening to his/her sung performance. Several acoustical parameters of the Western operatic singing technique have been studied ... [more ▼]

Objective: One can easily recognize the musical style of a singer by listening to his/her sung performance. Several acoustical parameters of the Western operatic singing technique have been studied. However, the number of parameters could be extended and the effect of melody on these parameters remains unclear. By observing the effects of melody and technique on acoustical and musical parameters of the singing voice, this study aims at further characterizing the Western operatic singing technique. Methods: Fifty professional singers performed two contrasting melodies (popular song and romantic melody) with two vocal techniques (with and without operatic singing technique). The common quality parameters (energy distribution, vibrato rate and extent), perturbation parameters (standard deviation of the fundamental frequency, signal-to-noise ratio, jitter and shimmer) and musical features (fundamental frequency of the starting note, average tempo, and sound pressure level) of the 200 sung performances were analyzed. Results: The results show that the choice of melody had a limited impact on the acoustical and musical parameters observed, whereas a particular vocal profile appeared depending on the vocal technique employed. By examining these parameters in a theoretical model, this study highlights the relevance of vibrato rate, sound level, energy distribution, fundamental frequency of the starting note and tempo in describing the Western operatic singing technique. Conclusions: This study confirms that vocal technique affects most of the parameters examined and that the effect of melody is limited. In addition, the observation of quality and musical parameters contributes to a better understanding of the operatic singing technique. Conversely, the perturbation parameters don’t seem to take part in the characterization of operatic singing voices. Although the suggested theoretical model needs to be further developed in future research, it already generates implications for research and teaching. [less ▲]

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See detailDesign of a sprayer that makes CE-ESI-MS easy and robust
Far, Johann ULg; De Pauw, Edwin ULg; Falmagne, Jean-Bernard et al

Conference (2014, May 28)

Presentation of a CEMS interface design for easy and robust coupling of Capillary Electrophoresis with Mass Spectrometry equipped with a nanospray source. Principles and specification were presented.

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See detailDesign of a spherical array of microphones for room acoustics applications.
Feron, Hermine; Embrechts, Jean-Jacques ULg

Conference (2014, May 28)

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See detailRegulation in Practice: Choice among regulatory Tools
Bougnouch, Mehdi ULg; Gautier, Axel ULg

Conference (2014, May 28)

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See detailSynthesis of hybrid nanoparticles for theranostics
Liu, Ji ULg; Detrembleur, Christophe ULg; Duguet, Etienne et al

Conference (2014, May 28)

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See detailDomain generality of serial order processing in short-term memory: Evidence from musical and verbal domains
Gorin, Simon ULg; Majerus, Steve ULg

Conference (2014, May 27)

Recent models of verbal short-term memory (STM) propose a distinction between item storage processes, which are viewed as domain-specific, and order storage processes, which are considered by some authors ... [more ▼]

Recent models of verbal short-term memory (STM) propose a distinction between item storage processes, which are viewed as domain-specific, and order storage processes, which are considered by some authors to be domain-general, at least as regards verbal and visual STM domains. Here we provide further evidence for domain-specific item STM processes and domain-general order STM processes by comparing item and order processing in verbal and musical STM domains. The musical domain is particularly relevant here given its reliance on different kinds of sequential processes (e.g., tones successions, rhythm). Using an interindividual differences approach, we administered to a group of young healthy adults different tasks requiring retention of item identity for words or tones, and tasks requiring retention of serial order information for word sequences or note sequences, as well as a task measuring retention abilities for rhythmic information. For the item STM tasks, we observed strong intercorrelations for within-domain WM measures, but not between-domain WM measures, after controlling for general WM abilities. For the serial order STM tasks, we observed a specific association with the rhythm STM task. These results highlight the importance of temporal sequential processes, as measured by the rhythm STM task, as a driving factor of domain-general STM processes in verbal and musical domains. They furthermore confirm the domain-specificity of item STM processes. [less ▲]

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See detailMaintaining people with multiple sclerosis at work: Validation of a questionnaire identifying their professional difficulties
Blavier, Adelaïde ULg; Monisse, Aurélie; Berkail, Radia et al

Poster (2014, May 27)

The purpose of this paper is to present the construction and validation of a questionnaire in order to evaluate the specific work difficulties and compensation mechanisms developed by multiple sclerosis ... [more ▼]

The purpose of this paper is to present the construction and validation of a questionnaire in order to evaluate the specific work difficulties and compensation mechanisms developed by multiple sclerosis patients (MS). At the moment, only few very recent questionnaires (in English) are constructed in order to highlight the link between the patients’ cognitive deficits with their professional situation (Doogan & Playford, 2014; Honan et al., 2012; McFadden et al., 2012). This lack of accurate assessment is detrimental to the patients’ job retention. Our questionnaire was constructed from review of literature and interviews of patients and experts. In order to validate our questionnaire and to test its specificity to MS patients, three groups of participants answered the questionnaire: MS patients, diabetic patients (diabetes is also a chronic illness but without any cognitive deficits contrary to MS) and a control group. We controlled the effect of anxiety and depression and we conducted a factorial analysis that showed the existence of 3 factors: the ergonomic factor (that includes cognitive difficulties and resources and adaptation process), the description of work situation and the social support. The three groups of participants obtained similar results for the work description and the social support while the group of patients with MS obtained a higher score than the other 2 groups for the ergonomic factor. These results suggest that our questionnaire is specific to the MS population and to the difficulties they specifically meet in their work situations. These results highlight new research opportunities and specific ways to increase job retention in MS population. [less ▲]

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See detail[18F]UCB-H AS A BRAIN SV2A RADIOTRACER: A FIRST CLINICAL TRIAL
Bahri, Mohamed Ali ULg; Bastin, Christine ULg; Aerts, Joël ULg et al

Poster (2014, May 27)

[18F]UCB-H is a fluorine-18 radiolabelled PET imaging tracer with a high affinity for the synaptic vesicle protein 2A (SV2A). This protein, involved in vesicle trafficking and widely distributed in the ... [more ▼]

[18F]UCB-H is a fluorine-18 radiolabelled PET imaging tracer with a high affinity for the synaptic vesicle protein 2A (SV2A). This protein, involved in vesicle trafficking and widely distributed in the brain, represents the binding site and the primary mechanism of the antiepileptic drug levetiracetam. Levetiracetam has recently been suggested to reduce synaptic deficits in a mouse Alzheimer’s disease model and to improve cognition in patients with amnestic mild cognitive impairment, suggesting a possible role for this protein in synaptic integrity. The objective of this study was to investigate the cerebral distribution of [18F]UCB-H in healthy human volunteers. Dynamic PET imaging of the head of four healthy volunteers was performed over 100 minutes after injection of 170.4 ± 24.9 MBq of GMP produced [18F]UCB-H. The input function was acquired by arterial blood sampling during the dynamic PET acquisition. Blood data analysis showed a consistent tracer amount in whole blood and plasma indicating a very low degree of binding of the tracer to the red blood cells. Unchanged [18F]UCB-H fraction in plasma follows a bi-exponential behavioral decrease with a starting fraction of 92% of the injected amount of the tracer, measured at 3 min post injection. This fraction decreases to about 50% at 10 min post injection. The [18F]UCB-H PET data revealed a high and rapid uptake in the grey matter structures, matching the known ubiquitous distribution of SV2A in the brain. The kinetics of the tracer in the brain was characterized by an initial high uptake phase followed by rapid washout allowing the standard compartmental modeling (1-tissue compartment, 2-tissue compartment, and Logan graphical analysis). The three models gave consistent results. The two-tissue compartment model fitted the experimental data best and provided a total distribution volume of [18F]UCB-H in the brain greater than 7 mL/cm3 and a specific distribution volume around 3 mL/cm3. Our results indicate that [18F]UCB-H is a new radiotracer for brain SV2A proteins suitable for human studies. Further studies are warranted to assess SV2A modifications in neurological pathologies such as Alzheimer’s disease. [less ▲]

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See detailCorrelation and integration of the Rorschach Comprehensive System and the TCI-R questionnaire
Rentmeister, Daniel; Blavier, Adelaïde ULg; Di Piazza, Laetitia ULg et al

Poster (2014, May 27)

In this study, a dual purpose is sought. First, we statistically compare the Rorschach test interpreted by the Comprehensive System from J.E. Exner and the Temperament and Character Inventory – Revised by ... [more ▼]

In this study, a dual purpose is sought. First, we statistically compare the Rorschach test interpreted by the Comprehensive System from J.E. Exner and the Temperament and Character Inventory – Revised by R. Cloninger to highlight their differences and similarities. Second, through clinical cases, we discuss the relevance of integrating the results obtained by these two tools to establish a comprehensive and consistent psychological profile of an individual. For the statistical comparison, a sample of 27 “healthy” subjects (M = 24.37 years, SD = 2.75) was first submitted to the Rorschach test. Then, immediately after, each subject completed the TCI-R. A correlation analysis (Pearson Rho) was done between various Index and a Bonferroni adjustment was made. For the case studies, 3 subjects were recruited. Anamneses were carried out and the Rorschach test and TCI-R administered. Our first results, which are to be taken with caution because of the small number of subjects in the sample, must be qualified and discussed. From 2448 statistical comparisons, we select the most relevant and discuss different correlation results. The case studies show a concordance in social relationships and impulsivity; and show that the information peculiar to each test allows us to complete the subject’s profile. Finally, it is by addressing two different epistemologies underlying these two tests that we can best explain the psychological differences highlighted in the same individuals. We conclude by suggesting that this difference in results must certainly be understood in an integrative logic and emphasizes the complementarity between these two tests. [less ▲]

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See detailSynthesis of a glucosamine labeled amphiphilic polymer for drug delivery application
Riva, Raphaël ULg; Boyère, Cédric; Debuigne, Antoine ULg et al

Poster (2014, May 27)

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See detailDetection of eye movements specific to drowsiness and their relation with subjective assessment: A cognitive ergonomic approach.
Blavier, Adelaïde ULg; Montagnino, Cédric; Wertz, Jérôme ULg et al

Poster (2014, May 27)

Drowsiness is one of the major factors explaining accidents, particularly in traffic accidents but also in work situations with serious consequences (e.g. medicine). The drowsiness may be assessed by ... [more ▼]

Drowsiness is one of the major factors explaining accidents, particularly in traffic accidents but also in work situations with serious consequences (e.g. medicine). The drowsiness may be assessed by diverse measures that vary from physiological and unconscious data (e.g. EEG) to subjective and conscious evaluation. In their daily life, people are used to evaluate their drowsiness by subjective assessment and research observes a great inter-individual variation in this evaluation. Moreover, the subjective evaluation is dependent on the situation and the risk perceived by the person (e.g., new versus usual situations, simple versus complex environments, etc.). In this theoretical context, our purpose was to investigate the links between 1) objective performance (reaction time) measured by a psychomotor vigilance task (PVT), 2) data from eye movements and 3) subjective assessment of drowsiness (measured with Karolinska Sleepiness Scale, KSS). 12 persons, aged from 20 to 56, participated individually. They were asked to respect a 60% sleep deprivation during the night before the experiment and to not drink any energy drinks the day of the experiment. The experiment was conducted between 1 and 3 PM after a heavy lunch in order to increase the circadian effect. Moreover, the temperature of the room was 25° in order to increase drowsiness. Each participant was asked to perform 4 PVT. However, although 100% of participants performed the first two PVT, only 66% were able to perform the third PVT and only 33% of participants performed the fourth and last PVT. Our results showed an effect of time on objective performance, eye movements and subjective assessment of drowsiness in PVT 1 and 2: significant increase of reaction time, increase of eye closure and perclos, reduction of pupil diameter and increase of subjective drowsiness estimation (KSS). Only the frequency and duration of blinks remained constant across time. In PVT 3 and 4, data from eye movements and objective performance (reaction time) did not vary anymore across the time. Only the subjective estimation of drowsiness (KSS) continued to increase. Furthermore, subjective estimation of drowsiness was differently correlated with eye movements and objective performance across the PVT; it was significantly correlated with reaction time (PVT 1,2,3), blink frequency and duration (PVT 1,2,3), perclos (PVT 1,2,3,4), eye closure (PVT 2,3), pupil diameter (PVT 1,2,3,4). These results are discussed and integrated in an ergonomic approach in order to analyze the links between objective performance, eye movements and subjective assessment of drowsiness. [less ▲]

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See detailLong protocols to Rorschach Comprehensive System and a posteriori reduction of number of responses: What is the impact on the clinical interpretation ?
Dufour, Cristelle; Englebert, Jérôme ULg; Blavier, Adelaïde ULg

Poster (2014, May 27)

Our study was interested in the exceptionally long protocols, superior to 55 answers, supplied by five subjects in the test of Rorschach according to the method of the Comprehensive System. In order to ... [more ▼]

Our study was interested in the exceptionally long protocols, superior to 55 answers, supplied by five subjects in the test of Rorschach according to the method of the Comprehensive System. In order to gain understanding of which attitude to adopt in front of this kind of protocol, we made a a posteriori reduction of the number of answers by basing us on the recommendations of Exner (Exner, on 2001), then a comparative study between the clinical interpretation realized with all of the answers and with only the first five answers by board. We also replicate this methodology of a posteriori decrease of the number of answers with four answers by board according to the new recommendations of the system R-PAS of Meyer and al. (Meyer and al, on 2009). The sample consists of three raw coal subjects and two psychiatric subjects. Our analysis highlighted a stability of certain variables (EB, Lambda, EA for example) but a difference in the psychological profile of the subjects after reduction. We observed a clarification of the fundamental difficulties to the psychiatric subjects and rather a neutralization of these difficulties for the raw coal subjects, with particularly defence mechanisms which seem more adapted. In our sample, the consideration of all of the answers or only of the partial protocol thus brings a difference in the clinical interpretation ; as a consequence any reduction should be made with big caution. Our study allows to discuss current practices of the test of Rorschach, by looking for a compromise between the inherent constraints to the validity of the test and the questions of the clinical complexity decrease appropriate to any initiative of standardization. [less ▲]

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