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See detailLes voix des "maladies rares" en Belgique : enquête multi-située sur les dynamiques de (re)connaissance d'une catégorie multiple
Duysens, Fanny ULiege

Conference (2017, September 29)

Les "maladies rares" se définissent par un taux de prévalence inférieur à 1 personne sur 2000 en Europe, ainsi que par un ensemble de situations et de problématiques caractéristiques que rencontrent les ... [more ▼]

Les "maladies rares" se définissent par un taux de prévalence inférieur à 1 personne sur 2000 en Europe, ainsi que par un ensemble de situations et de problématiques caractéristiques que rencontrent les patients et les proches concernés. Mais si la catégorie est aujourd'hui largement répandue à travers le monde, les sens qui lui sont donnés et les usages locaux dont elle fait l'objet n'ont rien d’évident. A partir d'une enquête ethnographique multi-située menée dans le contexte de la Belgique, cette recherche doctorale (2015-2018) étudie les processus de construction et de mobilisation de la catégorie de "maladies rares". Il s'agit de "suivre la catégorie" (Marcus, 1995) sur de multiples sites publics et intimes, individuels et collectifs, locaux et globaux, afin d'observer les représentations, les activités et les rapports entre diverses parties-prenantes : des associations de patients et de proches, des spécialistes scientifiques, médicaux et paramédicaux, et des acteurs de santé publique. Comment certaines formes de mobilisations des parties-prenantes observées sur le terrain belge permettent-elles de maintenir, d'étendre ou de modifier la catégorie de "maladies rares" en vue de (re)connaître celle-ci ? Le texte (working paper) qui a été discuté lors de l'atelier doctoral développait une partie du cadre d'analyse de la recherche. [less ▲]

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See detailLiège Souffle Vert : étude d’un parcours urbain végétalisé
Brahy, Rachel ULiege

Conference (2017, September 29)

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See detailLe cinéma déboussolé
Pieron, Julien ULiege

Conference (2017, September 29)

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See detailLe Stress Oxydant: arnaque ou biologie d'avenir?
LE GOFF, Caroline ULiege

Conference (2017, September 28)

Detailed reference viewed: 24 (1 ULiège)
See detailVitamine D et Vitamin D Binding protein
VRANKEN, Laura ULiege

Conference (2017, September 28)

Detailed reference viewed: 17 (0 ULiège)
See detailAltered antimicrobial peptide expression in HPV-related (pre)neoplastic lesions
Lebeau, Alizée ULiege

Conference (2017, September 28)

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See detailLa critique dans l'université contemporaine. Responsabilité et complexité.
Bachelet, Jean-François ULiege

Conference (2017, September 28)

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See detailDébattre la mesure : l'engagement politique de Steve Reich
Orianne, Jean-François ULiege

Conference (2017, September 28)

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See detailPhenomenology and metaphysics
Seron, Denis ULiege

Conference (2017, September 28)

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See detailPrevenzione quaternaria, primum non nocere
Jamoulle, Marc ULiege

Conference (2017, September 28)

When presented in Durham during the 1995 WICC workshop, the concept of quaternary prevention, born in 1986, has attracted the consensus of the whole audience. In 2003 it has been discretely published in ... [more ▼]

When presented in Durham during the 1995 WICC workshop, the concept of quaternary prevention, born in 1986, has attracted the consensus of the whole audience. In 2003 it has been discretely published in the Wonca dictionary of general practice. Since this time, medicine has changed. The diffusion of knowledge and the sagacity of some researchers has shown that medicine could become dangerous for health. The concepts of overinformation, overdiagnosis, overtreatment and overscreening are now the bread and butter of numerous medical journals and the themes of numerous books and disputes throughout the world. Quaternary prevention encompasses all those domains and supersedes them by putting the relationships between patient and doctor at the center of the ethical reflection. WICC has been instrumental in the genesis and dissemination of the concept of quaternary prevention. This concept is now known and distributed worldwide under the acronym P4. Family physicians form interlinked P4 groups in various countries. It is the theme of many congresses and was propelled to the forefront of the recent Wonca Europe Congress. This concept could induce profound changes in the role of the family physician in health care. Moreover, the combination of the four definitions of prevention provided an amazing view of the activity of family physicians and could renew basic job description in GP / FM. [less ▲]

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See detailL’organisation du culte islamique en Belgique
Husson, Jean-François ULiege

Conference (2017, September 28)

This paper presents the current organisation of the Muslim community in the context of Islam as a recognised religion in Belgim. The Muslim representative body, mosques and imams and specific aspects ... [more ▼]

This paper presents the current organisation of the Muslim community in the context of Islam as a recognised religion in Belgim. The Muslim representative body, mosques and imams and specific aspects (chaplaincies, religious education,...) are also dealt with. [less ▲]

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See detailA mathematical model of respiration under protective ventilation and extracorporeal CO2 removal therapy
Habran, Simon ULiege; Desaive, Thomas ULiege; MORIMONT, Philippe ULiege et al

Conference (2017, September 27)

The aim of the present study is to build a mathematical model of the respiratory system connected to an extracorporeal CO2 removal device (ECCO2RD) to optimize the gas exchanges efficiency. The model must ... [more ▼]

The aim of the present study is to build a mathematical model of the respiratory system connected to an extracorporeal CO2 removal device (ECCO2RD) to optimize the gas exchanges efficiency. The model must be simple enough to provide rapid solutions and to estimate specific parameters from available clinical data. But it also must be complex enough to be able to simulate the respiratory system when protective ventilation is used and when this system is assisted by an ECCO2RD. [less ▲]

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See detailPhotosharing on flickr: a data source for assessing cultural values in urban landscapes
Ginzarly, Manal ULiege

Conference (2017, September 27)

The urban landscape is a stratification of natural, cultural, and socio-economic processes that shape it spatially and experientially over time. The different cultural values embedded in the tangible and ... [more ▼]

The urban landscape is a stratification of natural, cultural, and socio-economic processes that shape it spatially and experientially over time. The different cultural values embedded in the tangible and intangible attributes of the urban landscape are essential to its unique sense of place, and cultural identity. In the era of globalization, rapid urbanization, and unsustainable urban development, cultural heritage has been recognized as an enabler for sustainable development that adapts, and evolves through time with the changes occurring in the city, and at the same time maintains its identity, integrity, and continuity. In this context, UNESCO recommended the application of the Historic Urban Landscape (HUL) approach to the management of thoughtful change and the conservation of cultural heritage. According to the HUL approach cultural values should be taken as a starting point in urban management and development. It is important that decision makers and experts are aware of the potential and variety of cultural values present within exceptional, ordinary, and even deteriorated urban landscapes. In recent years we have witnessed rapid advances in social networking and photo-sharing communities that are generating big data including geographic information, photos, and commentaries. Our assumption is that the phenomenon of user-generated data from social media offers awareness about the dynamic social interactions within places, and express moments, experiences, practices, and identities contributing to the understanding of cultural values associated with the urban landscape. Accordingly, this paper extracts, analyses, and visualizes photos metadata of Tripoli, Lebanon published on Flickr for the application to the fields of urban management and conservation. [less ▲]

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See detailLes expériences de mort imminente: le point de vue des neurosciences
Martial, Charlotte ULiege

Conference (2017, September 27)

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See detailDe la R&D à la mise sur le marché de produits industriels, évolutions de la recherche au service des entreprises
Blecker, Christophe ULiege

Conference (2017, September 26)

Ce séminaire retrace par des exemples concrets de développement de produits l'évolution des interactions entre le secteur alimentaire et la recherche fondamentale et appliquée. L'objectif est de mettre en ... [more ▼]

Ce séminaire retrace par des exemples concrets de développement de produits l'évolution des interactions entre le secteur alimentaire et la recherche fondamentale et appliquée. L'objectif est de mettre en avant l'apport de certaines méthodes de travail pour obtenir un partenariat entreprises-centres de recherche optimal. Pour conclure, il présente les principaux résultats de recherche dont son domaine dont les entreprises pourraient trouver un intérêt. [less ▲]

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See detailLa lettera e l’atmosfera. L’opera di Simenon al cinema
Tomasovic, Dick ULiege

Conference (2017, September 23)

Si l’œuvre de Simenon apparaît comme une évidente vache à lait de l’adaptation cinématographique (récits populaires, formes simples, personnages caractérisés, intrigues criminelles bien ficelées, force ... [more ▼]

Si l’œuvre de Simenon apparaît comme une évidente vache à lait de l’adaptation cinématographique (récits populaires, formes simples, personnages caractérisés, intrigues criminelles bien ficelées, force dramaturgique évidente), elle a aussi exercé une forte séduction sur un nombre important de cinéastes pour ses qualités descriptives, ses peintures sociales, et, surtout, pour une tonalité atmosphérique qui lui serait propre. Partant d’un rapide panorama des adaptations filmiques des œuvres de Simenon, cette intervention s’efforcera, à travers le commentaire de quelques œuvres déterminantes, de cerner la question de la mise en scène cinématographique de la fameuse atmosphère simenonienne. [less ▲]

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See detailLes enjeux didactiques de la mobilité étudiante en Francophonie : état des lieux et perspectives
Meunier, Deborah ULiege

Conference (2017, September 23)

En quoi les programmes de mobilité étudiante universitaire obligent-t-ils à repenser la didactique des langues et des cultures, ses objectifs, ses ambitions, ses conditions d’existence, ses modes ... [more ▼]

En quoi les programmes de mobilité étudiante universitaire obligent-t-ils à repenser la didactique des langues et des cultures, ses objectifs, ses ambitions, ses conditions d’existence, ses modes d’expression locaux ? Quelles sont les spécificités de l’enseignement-apprentissage du français à/par ces étudiants en séjour dans des universités francophones ? Après une brève mise en contexte sociohistorique de la mobilité étudiante, en particulier en Francophonie, nous proposerons, d’une part, un état des lieux des recherches sur l’enseignement du français pour ce public d’étudiants universitaires nomades et plurilingues, et, d’autre part, quelques résultats de nos recherches passées et en cours. L’objectif de cette communication sera de présenter des pistes susceptibles de pallier le vide pédagogique et les difficultés rencontrées par les enseignants et les étudiants mobiles. Ce public d’apprenants, à la fois « exigeant et fuyant » (Anquetil, 2011), nécessite des ajustements, des dispositifs, des méthodes à la fois pluriels et spécifiques, dont nous tracerons les lignes principales. Notre intervention bénéficiera d’un triple éclairage : celui de la littérature scientifique récente (notamment les travaux de chercheurs publiés dans un numéro du Langage et l’Homme, à paraitre en juin 2017, que nous coordonnons) ; de notre recherche doctorale sur les représentations des acteurs (institutions et étudiants) à propos de la mobilité étudiante en Europe et des langues, en particulier du français (2013) ; et enfin, d’une recherche actuelle que nous menons sur les compétences écrites en français d’étudiants universitaire non francophones, débutée en 2016 à l’université de Sherbrooke, au Québec. [less ▲]

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See detailThe weapon system behind the point: Early Gravettian hunting technologies at Maisières-Canal
Taipale, Noora ULiege; Coppe, Justin ULiege; Touzé, Olivier ULiege et al

Conference (2017, September 23)

Hunting and preparing for the hunt – manufacturing, using, and repairing the equipment – were undoubtedly important and time-consuming activities in the lives of Palaeolithic groups [1, 2]. Studying ... [more ▼]

Hunting and preparing for the hunt – manufacturing, using, and repairing the equipment – were undoubtedly important and time-consuming activities in the lives of Palaeolithic groups [1, 2]. Studying hunting equipment in detail is thus essential for our understanding of a crucial aspect of Palaeolithic human behaviour and allows us to understand developments in human technologies and problem-solving across wide geographical and chronological ranges. Yet, our current knowledge about the development of prehistoric hunting technologies (projecting modes, weapon design) is mainly based on a few important but isolated discoveries of organic remains in Europe, such as the Lower Palaeolithic spears or spear fragments recovered at Schöningen, Lehringen, and Clacton-on-Sea, the Solutrean and Magdalenian spear-thrower hooks, and the arrows and bow fragments from Mesolithic and Neolithic contexts [3]. In this paper we demonstrate how to exploit the full potential of a much more durable and ubiquitous type of remains, lithic armatures, in the study of Palaeolithic hunting practices. We present the results of a collaborative project that combines technological and functional analysis with experimental archaeology, and aims at understanding the manufacture and use of a specific lithic projectile type, the Early Gravettian tanged point. Our archaeological material comes from the Gravettian occupation phase of the open-air site of Maisières-Canal (Belgium), dated between 33 and 32 cal BP [4]. This stratigraphically well-isolated sequence has yielded an important collection of tanged points that are in excellent state of preservation. A combined study of the finished armatures and the related shaping waste allows us to present a new, more comprehensive view of the characteristics and constraints of the shaping method. The points were made on large, thin blades produced by hard or soft stone percussion, and subsequently shaped by several generations of direct, flat, invasive (sometimes overshot) removals with an organic hammer. These points, which all display a long, elaborately shaped tang, thus form a distinct tool type with a unique chaîne opératoire and a very particular morphology in terms of weapon design and hafting systems. Many of the points show clear macroscopic and microscopic damage from impact that can be attributed to their use as armatures. The morphology, the organisation, and the orientation of the traces allowed us to propose specific hafting modes that were tested experimentally. The experimental program focused on both the details of the hafting mode and the mode of projection. In addition, alternative tool uses such as butchering were considered, and the points were framed within the broader functional context of tanged and non-tanged tools recovered at the site. The results allow evaluating what kind of weapon system the tanged points were part of, and what their place was in the Early Gravettian technology. We argue that when approached from an experimental and techno-functional point of view, lithic projectile points can help us understand the development of hunting technologies as well as broader patterns of technological change. References:[1] Ellis, C.J., 1997. Factors influencing the use of stone projectile tips. In: Knecht, H. (Ed.), Projectile Technology. Springer Science & Business Media, pp. 37–74 [2] Greaves, R ., 1997. Hunting and multifunctional use of bows and arrows. In: Knecht, H. (Ed.), Projectile Technology. Springer Science & Business Media, New York, pp. 287–320 [3] Knecht, H., 1997. Projectile technology. Springer Science & Business Media, New York [4] Jacobi, R. M., Haesaerts, P., Jadin, I., Basell, L.S., 2010. Radiocarbon chronology for the Early Gravettian of northern Europe: new AMS determinations for Maisières-Canal, Belgium. Antiquity 84 (323), 26–40 [less ▲]

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See detailLes interactions enseignant/enfants comme soutien au développement langagier des enfants en classe maternelle
Leroy, Sandrine ULiege; Bergeron-Morin, Lisandre ULiege; Desmottes, Lise ULiege et al

in Les entretiens de Bichat : les entretiens d'orthophonie 2017 : Les pathologies du langage chez l'enfant de moins de 6 ans: facteurs de risque (FR), facteurs de protection (FP) (2017, September 22)

L'école maternelle constitue un contexte privilégié pour soutenir le développement du langage et de la communication des enfants. La qualité des interactions entre l’enseignant et les enfants de sa classe ... [more ▼]

L'école maternelle constitue un contexte privilégié pour soutenir le développement du langage et de la communication des enfants. La qualité des interactions entre l’enseignant et les enfants de sa classe est reconnue comme étant l’aspect le plus déterminant de la qualité éducative, notamment en ce qui concerne le développement langagier. Cet article a pour objectif de faire un survol de la littérature sur le développement du langage des enfants en contexte préscolaire, sur le rôle que peut y jouer l’enseignant, ce qui ouvre des perspectives quant aux modalités de développement professionnel des enseignants en maternelle. [less ▲]

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See detailNose and Sleep-disordered Breathing
POIRRIER, Anne-Lise ULiege

Conference (2017, September 22)

The nose is the input channel for the airflow. Its rigid and erectile structures determine the outline and the output of the airflow in the upper airway. Nose obstruction, due to reversible or non ... [more ▼]

The nose is the input channel for the airflow. Its rigid and erectile structures determine the outline and the output of the airflow in the upper airway. Nose obstruction, due to reversible or non reversible factors, produces collapsing forces that are manifest downstream in the collapsible pharynx. Moreover, nose pathologies result in unstable oral breathing, decreased activation of nasal-ventilatory reflex and reduced lung nitric oxide. Long-term oral breathing impacts on the craniofacial growth. The management of nose pathologies coud be medical, mechanical (nose dilators) or surgical. Nasal management should be integrated in a multimodal approach, considering the involvement of a multi-level obstruction, and truly reflecting the complexity of sleep disordered breathing. [less ▲]

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See detailSemantic externalism(s) and cognitive transparency
Leclercq, Bruno ULiege; De Brabanter, Philippe

Conference (2017, September 22)

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See detailTowards a covering aerospray method for quantitative analyses of pharmaceutical tablets using surface-enhanced Raman chemical imaging (SER-CI)
Cailletaud, Johan ULiege; De Bleye, Charlotte ULiege; Dumont, Elodie ULiege et al

Conference (2017, September 22)

In recent years, the use of SERS-CI in pharmaceutical sciences has increased in order to study the distribution of low-dose compounds in solid dosage forms [1]. This technique allows to improve the ... [more ▼]

In recent years, the use of SERS-CI in pharmaceutical sciences has increased in order to study the distribution of low-dose compounds in solid dosage forms [1]. This technique allows to improve the sensitivity of conventional Raman microscopy and to reduce significantly the image acquisition time by exalting the signal information. However, the applications of SERS-CI in the pharmaceutical field remain limited, especially due to the difficulty of obtaining a homogeneous deposit of metallic nanoparticles on the sample surface. Generally, the covering method used on the tablet is a drop casting deposition due to its simplicity and rapidity of implementation. Despite the colloidal solution deposit is not fully controlled. The inhomogeneous covering is the result of the “coffee-ring” effect that concentrates the nanoparticles at the edges of the droplet [2]. This implies remarkable variations of the SERS analyte signal’s intensity at different places. For a more reproducible and homogeneous coating, an aerospray method using a homemade apparatus was developed (Figure 1). The device is composed with a pair of coaxial tubes, the colloidal solution is pulled through the inner tube from a syringe pump and the outer tube is connected to a source of high pressure gas. Nitrogen, used as a nebulizing gas, creates a flow of small droplets of nanoparticles that are nearly dry when they hit the sample surface. The aerospray device is easy to implement and the entire surface of the tablet is covered by the SERS substrate in a homogeneous way. By using this covering method, the potential of SERS-CI is improved and making it a suitable technique for quantitative analyses of low drug concentrations or impurities in pharmaceutical tablets. [less ▲]

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See detailConférence d'ouverture : La morale de 1964 : une écriture en débats
Cormann, Grégory ULiege; Bourgault, Jean

Conference (2017, September 22)

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See detailPsychological Predictors and Consequences of Hearing Health Behaviors in Older Adults
Marquet, Manon ULiege; Chasteen, Alison L; Plaks, Jason E et al

Poster (2017, September 22)

Introduction: Hearing loss is a common chronic condition affecting older adults in Western populations [1, 2]. Even if older adults could benefit from hearing aid use, they are reluctant to wear them [1 ... [more ▼]

Introduction: Hearing loss is a common chronic condition affecting older adults in Western populations [1, 2]. Even if older adults could benefit from hearing aid use, they are reluctant to wear them [1]. The purpose of the present study was twofold: a) to examine whether older adults’ implicit theories regarding the modifiability of abilities in general would predict their hearing health behaviors; and (b) to assess consequences of these behaviors on subjective aging. Methods: One hundred and sixty-three older adults (Mean age = 68.62, SD = 5.40) completed, among other questionnaires, questions assessing their implicit theories of ability (i.e., seeing general abilities as fixed vs. improvable with effort [3]) and their subjective age (i.e., felt age, do age, look age, and interest age [4]). They also reported their perceptions of the benefits of various hearing health behaviors for slowing the effects of aging (i.e., getting their hearing tested and using hearing aids) as well as their intentions to engage in those behaviors. Results: We found that the more older people considered that abilities are alterable, the more they perceived hearing health behaviors as being beneficial, which in turn increased their intentions to engage in these behaviors. Also, the greater their intentions, the younger subjective age they reported. Key conclusions: These relationships between implicit theories, hearing health behaviors, and subjective age are particularly important to take into account. Indeed, neglecting hearing problems and experiencing an older subjective age may have detrimental health-related outcomes over time [5, 6]. 1. Feder, K., Michaud, D., Ramage-Morin, P., McNamee, J., & Beauregard, Y. (2015). Prevalence of hearing loss among Canadians aged 20 to 79: Audiometric results from the 2012/2013 Canadian Health Measures Survey. Health Reports, 26(7), 18-25. 2. Lin, F. R., Thorpe, R., Gordon-Salant, S., & Ferrucci, L. (2011). Hearing loss prevalence and risk factors among older adults in the United States. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 66(5), 582-590. doi: doi:10.1093/gerona/glr002 3. Dweck, C. S. (1999). Self-theories: Their role in motivation, personality, and development. Philadephia, PA: Psychology Press. 4. Kastenbaum, R., Derbin, V., Sabatini, P., & Artt, S. (1972). “The ages of me”: Toward personal and interpersonal definitions of functional aging. The International Journal of Aging and Human Development, 3(2), 197-211. 5. Bainbridge, K. E., & Wallhagen, M. I. (2014). Hearing loss in an aging American population: Extent, impact, and management. Annual Review of Public Health, 35, 139-152. doi: 10.1146/annurev-publhealth-032013-182510 6. Kotter-Grühn, D., Kornadt, A. E., & Stephan, Y. (2015). Looking beyond chronological age: Current knowledge and future directions in the study of subjective age. Gerontology, 62(1), 86-93. doi: 10.1159/000438671 [less ▲]

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See detailMyoferlin controls mitochondrial structure in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness
Rademaker, Gilles ULiege; Hennequière, Vincent ULiege; Brohée, Laura ULiege et al

Poster (2017, September 22)

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer, and the third leading cause of cancer related death. Therapeutic options remain very limited and are still based on ... [more ▼]

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer, and the third leading cause of cancer related death. Therapeutic options remain very limited and are still based on classical chemotherapies. Cell fraction can survive to the chemotherapy and is responsible for tumor relapse. It appears that these cells rely on OXPHOS for survival. Myoferlin, a membrane protein involved in cell fusion was recently shown by our laboratory to be overexpressed in pancreatic cancer. In the present study, we discovered that myoferlin was more expressed in cell lines undergoing oxidative phosphorylation (OXPHOS) than in glycolytic cell lines. In the former cell lines, we showed that myoferlin silencing reduced OXPHOS activity and forced cells to switch to glycolysis. The decrease in OXPHOS activity is associated with mitochondrial network disorganization. Dynamin-related protein (DRP)-1 phosphorylation led us to suggest mitochondrial fission, reducing cell proliferation, ATP production and inducing autophagy and ROS accumulation. To confirm the clinical importance of myoferlin in PDAC, we showed that low myoferlin expression was significantly correlated to high overall survival. Myoferlin staining of PDAC sections was negatively correlated with several 18FDG PET indices indicating that glycolytic lesions had less myoferlin. As the mitochondrial function is demonstrated to enhance the cell resistance to the treatment, the metabolic switch forced by myoferlin silencing could open up a new perspective in the development of therapeutic strategies. [less ▲]

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See detailUn MOOC sur l’enseignement du FLE : la question de la médiation des savoirs et de l’évaluation des savoir-faire
Meunier, Deborah ULiege; Thonard, Audrey ULiege

Conference (2017, September 22)

« Ma classe de FLE » est un projet de MOOC destiné à de (futurs) enseignants de français langue étrangère. Constitué de 8 modules interactifs, ce MOOC vise à développer les connaissances et compétences ... [more ▼]

« Ma classe de FLE » est un projet de MOOC destiné à de (futurs) enseignants de français langue étrangère. Constitué de 8 modules interactifs, ce MOOC vise à développer les connaissances et compétences des participants en matière de gestion des interactions (orales et écrites) et des ressources (notamment numériques), mais aussi de développement des compétences grammaticales et interculturelles des apprenants. A partir d’exemples concrets d’activités, nous interrogerons d’un point de vue didactique deux aspects liés à ce dispositif d’enseignement/apprentissage innovant : la médiation des savoirs et les pratiques d’évaluation. En effet, les enjeux d’une pédagogie renversée, où l’apprenant est au centre de l’apprentissage et le numérique à son service, impliquent une (re)configuration des rôles des acteurs du dispositif (apprenants, enseignants, tuteurs, animateurs) dans la médiation des savoirs d’une part, et l’évaluation des acquis d’apprentissage d’autre part. Nous verrons comment nous avons mis en œuvre la co-construction collaborative et ouverte de savoirs, et quels dispositifs d’évaluation (par les pairs, par essai-erreur) nous avons proposés, en accord avec la pédagogie (inter)active dans laquelle s’inscrit notre projet de MOOC. [less ▲]

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See detailFacultative paedomorphosis in pond-breeding newts
Denoël, Mathieu ULiege

Conference (2017, September 21)

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See detailAtypical composition and structure of the mitochondrial dimeric ATP synthase from Euglena gracilis
Miranda Astudillo, Héctor Vicente ULiege; Yadav, Sathish; Colina-Tenorio, Lilia et al

Poster (2017, September 21)

Mitochondrial respiratory-chain complexes fromEuglenozoa comprise classical subunits described in other eukaryotes (i.e. mammals and fungi) and subunits that are restricted to Euglenozoa (e.g. Euglena ... [more ▼]

Mitochondrial respiratory-chain complexes fromEuglenozoa comprise classical subunits described in other eukaryotes (i.e. mammals and fungi) and subunits that are restricted to Euglenozoa (e.g. Euglena gracilis and Trypanosoma brucei). Herewe studied the mitochondrial F1FO-ATP synthase (or Complex V) fromthe photosynthetic eukaryote E. gracilis in detail. The enzymewas purified by a two-step chromatographic procedure and its subunit compositionwas resolved by a three-dimensional gel electrophoresis (BN/SDS/SDS).Twenty-two different subunits were identified by mass-spectrometry analyses amongwhich the canonical α, β, γ, δ, ε, and OSCP subunits, and at least seven subunits previously found in Trypanosoma. The ADP/ATP carrierwas also associated to the ATP synthase into a dimericATP synthasome. Single-particle analysis by transmission electron microscopy of the dimeric ATP synthase indicated that the structures of both the catalytic and central rotor parts are conserved while other structural features are original. These new features include a large membrane-spanning re- gion joining the monomers, an external peripheral stalk and a structure that goes through the membrane and reaches the inter membrane space below the c-ring, the latter having not been reported for any mitochondrial F-ATPase. [less ▲]

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See detailContinuing education with MOOCs. The case of children’s literature in French-speaking world
Dozo, Björn-Olav ULiege; Van de Poël, Jean-François ULiege; Centi, Valérie et al

Conference (2017, September 21)

1. Introduction Continuing education poses a challenge to the university: the objective is to allow professionals on the job market to enhance their competences through curricula adapted to their needs ... [more ▼]

1. Introduction Continuing education poses a challenge to the university: the objective is to allow professionals on the job market to enhance their competences through curricula adapted to their needs, both in terms of schedule and contents as well as teaching approaches applied. In its MOOCs policy, the University of Liège has identified this priority axis precisely to meet this requirement of schedule, contents and teaching approach. Already taught at the ULg, children's literature offered a perfect option for its pilot project. Popular culture studies are already one of the specificities of the Arts faculty program, and the University thought important to allow for a wider access to this teaching, responding to a growing interest from the civil society. 2. Problem description / challenges Up to now, there were, in French-speaking Belgium, only very few training opportunities on children's literature, based on cutting-edge scientific research, aimed at future or already established teachers. Although children's literature is one of the subject areas taught in secondary schools in French-speaking Belgium, it is not compulsory in the curriculum of aspiring French teachers at higher education institutions (whether universities or hautes écoles). Teaching children's literature thus depends on the teacher's good will: hence the importance of finding a way to train teachers in a subject area they have to teach to secondary school students by putting forward a large-scale but cost controlled solution, open to anyone looking for this specific training, and offering a certificate with a professional value. It was also important for the university to propose an innovative teaching format distinct from the practices generally in force and especially adapted to the adult-learning in terms of pedagogical approach (Thorpe,Edwards,Hanson, 1993). 3. MOOC Format Choosing the MOOC format was an important challenge: on the production level, above all, given the relative inexperience of the teaching staff, supported by a team of instructional designers and a production staff with experience in the creation of online contents for the University's online education platform; but also on the reception level, given that the expected audience is not particularly in line with digital technologies: MOOCs on literature are not the most common ones, and bookish readers are not known to be new technology buffs. The MOOC offers a selection of topics related to the field of children's literature, each under the responsibility of one team member, generally supported by experts. The MOOC tackles two main genres, the novel and the album, presents the publishing market, elaborates on digital literature and explores fictions beyond the book; it includes videos, quizzes, integrative activities, and feedback through forums. Each chapter of our MOOC adopts a modular and autonomous approach. These two characteristics allow learners to follow the MOOC according to their own needs or simply their interests. 4. Initial success The first session, in early March 2017, was a success, with more than 10000 subscribers, quite above the average for MOOCs in French. This is, for many subscribers, their first MOOC experience. Moreover, the motivation and investment of the community is remarkable: the forums are very active, the learners an-swer to and help each other. The feedback is extremely positive, showing a general willingness to partici-pate in the construction of collective knowledge useful for everyone. The information collected from participants is also an early success indicator in terms of population target. 5. Shaping Up for the Future Given this initial success, and in order to enhance this in-depth continued training, the teaching staff is envisioning for next year to develop a summer school linked to the MOOC and implement a blended learning element to our MOOC. The participants would first have to follow the MOOC and complete the required activities, in order to be granted certification. Afterwards, a limited number of these participants (probably around fifty) will be selected based on applications to participate in person to a course that would expand on the introduction to the subject offered by the MOOC. This training would highly benefit from the exceptional resources that the city of Liège holds for children's literature: the Michel Defourny archive, holding more than 30000 pieces, is indeed a unique site in Europe which deserves a better valorization from the University. [less ▲]

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See detailPerformance-based fire design and the U.S. prescriptive guidelines: A comparative study
Elhami Khorasani, Negar; Fang, Chenyang; Gernay, Thomas ULiege

in Proceedings of the 39th IABSE Symposium (2017, September 21)

Current codes and standards for fire design of structures in the United States are mainly based on design at the component level using prescriptive approaches, while performance-based design for fire can ... [more ▼]

Current codes and standards for fire design of structures in the United States are mainly based on design at the component level using prescriptive approaches, while performance-based design for fire can be used to address the needs for designing modern buildings with cost-effective solutions. Previous research shows that, when system-level performance is considered, fire protection on secondary beam elements in composite steel-concrete floor systems is not necessary due to the development of a membrane action in the concrete slab during fire. This study compares the fire design of a 9-story office building using prescriptive and performance-based designs. The safety levels of the two designs are investigated and compared. It is shown that performance-based design can be used to achieve the required level of safety currently enforced in the U.S. prescriptive guidelines, while providing an opportunity for cost reduction in fire protection material. [less ▲]

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See detailHealing effect of controlled anti-electromigration on conventional and high-Tc superconducting nanowires
Baumans, Xavier ULiege; Lombardo, Joseph ULiege; Brisbois, Jérémy ULiege et al

Conference (2017, September 21)

At the present time, electron beam lithography (EBL) is considered as the reference technique for nanoscale patterning. However, making nanostructures below the sub-10 nm scale is still challenging due to ... [more ▼]

At the present time, electron beam lithography (EBL) is considered as the reference technique for nanoscale patterning. However, making nanostructures below the sub-10 nm scale is still challenging due to broadening effects (forward electron scattering, backscattering, electrostatic charging…), and requires strong investment in terms of cost for state-of-the-art EBL systems. In this sense, alternative methods are continuously explored in order to make such nanofabrication easily reachable. A promising approach consists of inducing atomic diffusion by a large current density. This phenomenon, called electromigration (EM), and well known since the 60’s as a failure mechanism in metallic interconnections [1], still attracts interests from scientists and engineers for its great potential for fabrication of microstructures and for its reversibility character [2, 3]. In this work, we show that the combination of electromigration and anti-electromigration allows the precise tuning of superconducting properties of Al nanoconstrictions and we also observe the reversibility of electromigration failure for this material (see Fig. 1). The same process has been applied on Nb, leading to a more irreversible process, and La2 xCexCuO4. For the latter material, we show that selective migration of oxygen atoms and the consequent doping modification induces a transition from a superconducting state to an insulating state in a reversible way [4]. We also discussed the possibility to enhance the electromigration technique by replacing the complex feedback control by a technique of electropulsing. These researches have direct practical impact as a method to explore the dependence of the characteristic parameters on the exact oxygen content and pave the way for a reversible control of local properties of nanowires. [less ▲]

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See detailTowards the development of a dual mode fluorescence/SERS dopamine aptasensor
Dumont, Elodie ULiege; De Bleye, Charlotte ULiege; Cailletaud, Johan ULiege et al

Poster (2017, September 21)

This work was dedicated to the development of a dual mode fluorescence and surface-enhanced Raman scattering (SERS) dopamine aptasensor. The preparation of the aptasensor was first optimised. Thereafter ... [more ▼]

This work was dedicated to the development of a dual mode fluorescence and surface-enhanced Raman scattering (SERS) dopamine aptasensor. The preparation of the aptasensor was first optimised. Thereafter, calibration curves were realised by means of fluorescence quenching and SERS. Finally, the specificity of both methods was tested. [less ▲]

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See detailEffect of solution treatment on the fracture mechanisms of AlSi10Mg parts produced by Selective Laser Melting
Delahaye, Jocelyn ULiege; Mertens, Anne ULiege; Dedry, Olivier ULiege et al

Poster (2017, September 21)

Al alloy AlSi10Mg processed by Selective Laser Melting (SLM) displays high hardness and tensile strength due to its very fine eutectic microstructure [1]. However, as-built material exhibits low ductility ... [more ▼]

Al alloy AlSi10Mg processed by Selective Laser Melting (SLM) displays high hardness and tensile strength due to its very fine eutectic microstructure [1]. However, as-built material exhibits low ductility which is detrimental for applications where a high resilience is needed. To overcome this issue, solution heat treatment can be applied to soften and ductilize the material [2]. The very fine eutectic microstructure then turns into a dispersion of coarse globular Si precipitates. The distribution of Si precipitates seems to play a role in the fracture mechanism in as-built as well as solutionized tempers, but this effect is not yet fully understood [1,3]. Moreover, the lack of quantitative data makes it difficult to link precisely the fracture mechanisms to specific microstructural features. This study aims at investigating the role of the Si phase in the rupture mechanism, for both as-built and solutionized samples. It will focus more particularly on the heterogeneity of the distribution of Si precipitates where cracks are more likely to occur. Al cells size, along with the volume fraction and distribution of Si precipitates have been quantified by SEM image analysis. Al lattice parameter and Si crystallite size have been determined by X-ray diffraction/Rietveld analysis. For the image analysis, two types of specific zones have been observed i.e. the core and boundary of melt pools and Al grains, at different locations for representativity. These quantitative data have been compared with typical features observed on the fractured surface of tensile specimen. 1. D.-K. Kim et al. J. Alloys Compd. 686 (2016) 281. 2. W. Li et al., Mat. Sci. & Eng. A. 663 (2016) 116, 3. N.T. Aboulkhair et al. Mat. Sci. & Eng. A. 667 (2016) 139. [less ▲]

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See detailNon-classical structures and association of the OXPHOS complexes in Euglena gracilis and Polytomella sp.
Miranda Astudillo, Héctor Vicente ULiege; Yadav, Sathish; Colina-Tenorio, Lilia et al

Poster (2017, September 21)

To date, the idea that the OXPHOS complexes can associate with each other in larger structures named supercomplexes [1] is generally accepted. This association can allow a more efficient transport of ... [more ▼]

To date, the idea that the OXPHOS complexes can associate with each other in larger structures named supercomplexes [1] is generally accepted. This association can allow a more efficient transport of electrons to minimize the generation of reactive oxygen species during electron transfer reactions and can also be involved in the regulation of the mitochondrial metabolism in response to different stimuli, carbon sources or stress conditions. Recently, the arising studies outside the classical models yeast and bovine mitochondria brought to light many unusual characteristics in the ATP synthase from a wide variety of organisms. Due to this, the dimer nature of the mitochondrial ATP synthase is no longer a matter of debate. Given the large structural differences among the peripheral stator and dimerization modules of mitochondrial ATP synthases described so far, it is of relevance to study a wider number of species to gain insight into the structural diversity of their OXPHOS complexes. Recently, our group showed that at least 41 of the non-canonical subunits reported in trypanosomes are also present in Euglena complexes along with 48 classical subunits described in other eukaryotes including green plants [2]. Further purification of the complexes I, III, IV and V by liquid chromatography after solubilization with n-β-dodecyl-maltoside and the subsequent analysis by single-particle analysis from transmission electron microscopy revealed some unusual features in Euglena respiratory complexes. In the case of complex V the structures of both the catalytic and central rotor parts are conserved while other structural features are original, including a large membrane-spanning region joining the monomers, an external peripheral stalk and a structure that goes through the membrane and reaches the inter membrane space below the c-ring [3]. Complex I also shows an unusually long matricial arm. Complex IV shows an atypical shape compared to that of the bovine one. An unusual association between complexes I and V can be observed when the membranes are extracted with the mild detergent digitonin. Other case of atypical subunit composition is the complex V of chlorophycean algae. Each monomer of the enzyme has 17 polypeptides, eight of which are the conserved, main functional components, and nine polypeptides (Asa1 to Asa9) unique to this lineage that form the robust peripheral stalk in this complex [4]. This complex presents highly stable dimeric and tetrameric structures, and the respiratory complexes have an unusual capacity to reassociate in vitro and restore the functional respirasome. [less ▲]

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See detailQuelques pistes pour relancer la foresterie sociale et la participation en Afrique centrale
Vermeulen, Cédric ULiege

Conference (2017, September 21)

Detailed reference viewed: 92 (43 ULiège)
See detail“Flippons nos classes de FLE !" : Le modèle de classe inversée adopté à l’université de Liège pour l’enseignement/apprentissage du FLE
Thonard, Audrey ULiege

Conference (2017, September 21)

Dix ans après la création d’un premier dispositif d’apprentissage en ligne, l’Institut Supérieur des Langues Vivantes a souhaité revoir son intégration du numérique dans les cours de FLE destiné aux ... [more ▼]

Dix ans après la création d’un premier dispositif d’apprentissage en ligne, l’Institut Supérieur des Langues Vivantes a souhaité revoir son intégration du numérique dans les cours de FLE destiné aux étudiants Erasmus « in ». Dans cette communication, nous présenterons les contraintes et les opportunités qui ont modifié, lentement mais sûrement, notre conception de l’enseignement en ligne et celle de la classe inversée. [less ▲]

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See detailAgeism and dementia stigma among healthcare professionals
Schroyen, Sarah ULiege; Adam, Stéphane ULiege; Missotten, Pierre ULiege

Poster (2017, September 21)

Detailed reference viewed: 40 (3 ULiège)
See detailModel for the response of superconducting/ferromagnetic structures subjected to crossed fields
Vanderheyden, Benoît ULiege; Fagnard, Jean-François ULiege; Hogan, Kevin ULiege et al

Poster (2017, September 20)

Bulk (RE)BCO samples can be used as efficient permanent magnets with trapped magnetic flux densities of a few teslas at 77 K. However, their magnetization may decay over time when subjected to time ... [more ▼]

Bulk (RE)BCO samples can be used as efficient permanent magnets with trapped magnetic flux densities of a few teslas at 77 K. However, their magnetization may decay over time when subjected to time-varying parasitic fields perpendicular to the initial trapped flux density. In this work, we consider hybrid structures made of superconducting pellets and soft ferromagnetic rings or disks and investigate numerically how their magnetization varies under such crossed-field excitations. We consider a finite-element model in the A-V formulation, which is developed for both the full 3D configuration of the system and for a computationally lighter 2D approximation. The models provide the volumic distribution of current densities, the field lines, and the magnetization of the system, and the latter is compared to experimental measurements obtained with a bespoke magnetometer. A critical assessment is made outlining the advantages and limitations of the 2D approach. It is demonstrated that the ferromagnetic material helps in increasing the initial trapped field and in reducing the crossed-field effects. For the case of a single ferromagnetic disk put on top of the superconducting pellet, we study the dependence of the initial magnetization with respect to the disk thickness and the saturation field of the ferromagnetic material, and discuss the resulting optimal thickness. We also suggest different hybrid structures made of one superconducting pellet and one or several ferromagnetic disks or rings, and show numerically that a compromise is to be found between the maximum level of induction which can be reached and the improved protection against crossed-field effects. [less ▲]

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See detailThe Vedic Consecration and the Birth of the Hero in Sanskrit Epic
Swennen, Philippe ULiege

Conference (2017, September 20)

When they give birth to these heros, Arjuna's mother and Râma's mother are both compared to the Vedic goddess Aditi. This suggests that the author of the Mahâbhârata was comparing Arjuna to a Vedic ... [more ▼]

When they give birth to these heros, Arjuna's mother and Râma's mother are both compared to the Vedic goddess Aditi. This suggests that the author of the Mahâbhârata was comparing Arjuna to a Vedic sacrificer, which was perfectly clear for the author of the Râmâyana inspired by the Mahâbhârata. [less ▲]

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See detailLegitimating innovation by foreign traditions: the case of the Roman Republican divination
Berthelet, Yann ULiege

Conference (2017, September 20)

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See detailWP1 - A summary
Sanchez, Christelle ULiege

Conference (2017, September 20)

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See detailÉmile de LAVELEYE (1822-1892) et le « bon » gouvernement
Grandjean, Geoffrey ULiege

Conference (2017, September 20)

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See detailBreed fast, die young - Demography of a Neotropical fossorial frog
Székely, Diana ULiege; Székely, Paul; Stănescu, Florina et al

Poster (2017, September 19)

Information regarding age- and size-related parameters is of paramount importance both to understanding the life-history of populations, and for designing effective conservation strategies; however, such ... [more ▼]

Information regarding age- and size-related parameters is of paramount importance both to understanding the life-history of populations, and for designing effective conservation strategies; however, such base-line data lacks for many species, especially for those inhabiting tropical habitats. Using skeletochronology, we provide the first detailed information regarding the demography of the Pacific horned frog, Ceratophrys stolzmanni, a vulnerable, fossorial amphibian, that lives in the Tumbesian dry-forests of Ecuador. The species shows an intense growth rate during the first activity season, both before and after metamorphosis. Sexual maturity is achieved by both sexes before the first year of life, after which growth rates abruptly decrease. Females are on average larger, but not older, than males, mean age being two years in both sexes. The rapid sexual maturation is associated with a short life-span, the observed maximum longevity being three years in males and four years in females. The short reproductive life-span, which offers few mating opportunities, might have important implications for the conservation of this species, that can be especially at risk in the case of prolonged droughts expected to affect its habitat. [less ▲]

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See detailIdentification and quantitation of intact virus-like particles of human papillomavirus (HPV-VLP) using capillary electrophoresis
Bettonville, Virginie ULiege; Nicol, Jérôme; Furst, Tania et al

Conference (2017, September 19)

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See detailThe Cassini-Huygens mission: tale of a 13-year journey in the Saturnian system
Palmaerts, Benjamin ULiege

Conference (2017, September 19)

On the 15th of September 2017, the Cassini spacecraft will plunge into the atmosphere of Saturn, making the end of the successful Cassini-Huygens mission. During this unprecedented mission, Cassini will ... [more ▼]

On the 15th of September 2017, the Cassini spacecraft will plunge into the atmosphere of Saturn, making the end of the successful Cassini-Huygens mission. During this unprecedented mission, Cassini will have spent 13 years around Saturn, achieving almost 300 orbits around the planet and continuously collecting observations of Saturn, its rings, moons and space environment. In this talk, after a short introduction about the genesis of the Cassini mission, I will give a review of all the important results of the mission. The dynamics of Saturn's atmosphere and magnetosphere will be discussed, as well as the discoveries about the evolution of the rings. An important part of the presentation will be also devoted to the moons Titan and Enceladus which both exhibit striking characteristics. [less ▲]

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See detailA SPRAY DRYING METHOD FOR THE PREPARATION OF Na2FePO4F/CB AND Na2FePO4F/CNT COMPOSITES CATHODE FOR LITHIUM-ION BATTERIES
Mahmoud, Abdelfattah ULiege; Berardo, Loris ULiege; Brisbois, Magali et al

Poster (2017, September 18)

Fluorophosphates are considered among the most interesting series of cathode material for Li/Na-ion batteries1. Na2FePO4F (space group Pbcn), with its layered structure and two-dimensional pathways for ... [more ▼]

Fluorophosphates are considered among the most interesting series of cathode material for Li/Na-ion batteries1. Na2FePO4F (space group Pbcn), with its layered structure and two-dimensional pathways for facile Na+/Li+ transport, exhibits minimal structural changes upon reduction/oxidation. The average working voltage is 3.3 V vs. Li/Li+. Intercalation/deintercalation results in a volume change of only 3.7%. However, one of the key drawbacks of Na2FePO4F electrodes is their low intrinsic electronic conductivity. In order to study the effect of the carbon black and carbon nanotubes on the electrochemical performance of Na2FePO4F cathode material for lithium-ion batteries, Na2FePO4F, Na2FePO4F/CB and Na2FePO4F/CNT were prepared by a spray-drying method with different ratios of CB and CNT (10 and 20%). The crystal and local structure were analyzed by XRD and Mössbauer spectroscopy. The electrochemical properties were studied by galvanostatic cycling in lithium cells. The electrochemical performance is markedly better in the case of Na2FePO4F/CNT (20 wt%), with specific capacities of about 100 mAh/g (Na2FePO4F/CNT) at C/4 rate2 vs. 50 mAh/g for Na2FePO4F/CB. The characterization of Na2FePO4F/CB particles by electron microscopy revealed a carbon-poor surface and a good carbon dispersion for Na2FePO4F/CNT particles attributed to better diffusion of carbon nanotubes in the droplets during drying. References : 1-N. Eshraghi, S. Caes, A. Mahmoud, R. Cloots, B. Vertruyen, F. Boschini, Electrochim. Acta, 228 (2017) 319–324. 2-M. Brisbois, S. Caes, M-T. Sougrati, B. Vertruyen, A. Schrijnemakers, R. Cloots, N. Eshraghi, R-P. Hermann, A. Mahmoud, F. Boschini, Solar Energy Materials & Solar Cells 148 (2015) 67-72. [less ▲]

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See detailChallenges in the determination of amyloid oligomeric species by two electrophoretic techniques
Napp, Aurore ULiege; Houbart, Virginie ULiege; Demelenne, Alice ULiege et al

Poster (2017, September 18)

Parkinson’s disease is a frequent degenerative disorder, and for the moment the diagnosis is mainly clinical. When the first symptoms appear, loss of more than 70% of the dopaminergic cells already ... [more ▼]

Parkinson’s disease is a frequent degenerative disorder, and for the moment the diagnosis is mainly clinical. When the first symptoms appear, loss of more than 70% of the dopaminergic cells already occurred. Knowing that, it is of high interest to have one (or more) reliable biomarker(s) at our disposal to diagnose Parkinson before the first symptoms appear. Alpha-synuclein (aSyn) is a protein physiologically expressed at high level by neuronal cells, under a monomeric form. This protein would play a critical role in the development of the disease because under certain conditions, aSyn is capable of self-assembly to form fibrils like those found in Lewy bodies. Other intermediate soluble forms like dimers and oligomers are also formed. As these forms seems to be the toxic species, they are the center of many attentions. The quantification of each form would be a great help, but for the moment only the total forms (of monomeric or oligomeric) can be quantified. In this study, aSyn oligomers were generated after optimization of incubation conditions (pH, temperature, agitation, …). Then, different approaches were investigated to detect and follow the different species formed during the aggregation. We analyzed the oligomers by capillary gel electrophoresis (CGE) and SDS-PAGE. We found that capillary gel electrophoresis is a promising automated technique to analyze aSyn oligomers, due to the fact that it separates the aggregates according to their size, like the SDS-PAGE, but with more advantages. To gain sensitivity and selectivity by CGE, we used a laser-induced fluorescence detector. As aSyn do not have a native fluorescence, we derivatized it. After careful screening and optimization of various derivatization reagents, we could quantify with high sensitivity aSyn oligomers by CGE-LIF. We realized different calibration curves, and we had promising results that will allow us to quantify the different aSyn oligomeric forms in biological fluids. [less ▲]

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See detailRuralité et mondialisation dans l'oeuvre de Josef Winkler
Neelsen, Sarah ULiege

Conference (2017, September 15)

Une œuvre à ce point enracinée dans le paysage, la culture et la langue de l’Autriche semblait peu propice à intégrer les bouleversements de l’ordre mondial après 1989 et son auteur bel et bien enfermé ... [more ▼]

Une œuvre à ce point enracinée dans le paysage, la culture et la langue de l’Autriche semblait peu propice à intégrer les bouleversements de l’ordre mondial après 1989 et son auteur bel et bien enfermé dans une certaine tradition nationale. Pourtant à partir de 1996, les récits de voyage, journaux intimes et romans sur l'Inde se multiplient. La mondialisation semble donc bien avoir eu un impact profond sur son travail et l'étude approfondie du roman Roppongi montre comment se construisent des effets de résonance entre rituels funéraires hindous et catholiques. Cette communication analyse les différences entre interculturalité et mondialisation, lieux et non-lieux et conclut sur la tension entre la mobilité des corps et l'obsession de l'image fixe. [less ▲]

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See detailCoronagraphy and Interferometry: Imaging the sky at high contrast and high-angular resolution
Defrere, Denis ULiege; Absil, Olivier ULiege

Conference (2017, September 15)

Short overview of the main activities related to exoplanet imaging at the STAR Institute

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See detailHow classroom teachers do take the ‘Physical Activity Pauses at School’ (PAPS)? A project implemented in Wallonia
Cloes, Marc ULiege; Cloes, Stéphanie

Conference (2017, September 15)

In Wallonia, special efforts are needed in order to respect the international recommendations on physical activity in youth. School is definitely considered as a central pillar in the promotion of an ... [more ▼]

In Wallonia, special efforts are needed in order to respect the international recommendations on physical activity in youth. School is definitely considered as a central pillar in the promotion of an active lifestyle. The aim of this study was to analyze the implementation process of daily activity breaks called ‘Physical Activity Pause at School’ (PAPS) in 6 primary schools of the Liege area. 23 classroom teachers were involved. They had to propose at least one PAPS/day during the 15-16 school year. Diary, questionnaires, focus groups and interviews were used for data collecting. Two thirds of the subjects continued until the end. The videos were not systematically used. Four teachers’ profiles were identified: Innovators, Invested, Careful, and Disengaged. 12 factors facilitating or limitating the involvement of the teachers have been analyzed. The study comes to a model of concrete actions to respect in order to increase the chances of success in the implementation of such project. [less ▲]

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See detailFatigue resistant designs using stress-based topology optimization
Collet, Maxime ULiege; Bauduin, Simon ULiege; Fernandez Sanchez, Eduardo Felipe ULiege et al

Conference (2017, September 15)

Fatigue is an important mode of failure in mechanical engineering and accounting for it as soon as the early stage of design using topology optimization sounds primordial. Structures undergoing high-cycle ... [more ▼]

Fatigue is an important mode of failure in mechanical engineering and accounting for it as soon as the early stage of design using topology optimization sounds primordial. Structures undergoing high-cycle fatigue can be described by the stress-based approach and then a stress-based topology optimization framework, which has received great interest since almost 20 years because of the innovative designs that can be achieved to answer strength requirements, can be used. Literature reports many good results for shape optimization [Mrzyglod & Zielinsky(2006)] whereas in the eld of topology optimization several authors have shown that considering fatigue in an optimization framework leads to more relevant solutions where fluctuating loads are involved [Holmberg E.(2015), Collet et al(2016), Sv ard(2015)]. The good behaviour of the implementation of an advanced fatigue criterion, i.e. the multiaxial Dang Van criterion [Dang Van et al(1989)] is first investigated in the framework of a density-based topology optimization problem. The choice of this fatigue criterion is justifed by its good applicability in automotive or aeronautic industry as well as its relevancy with respect to experimental results. We present the sensitivity analysis with stress constraints and present some classical benchmarks to illustrate the behaviour of the optimized solution. In a second time, the fatigue resistance is introduced in the well-known microstructural design [Sigmund (2000)] also know as architectured material design which are now considered in mechanical engineering because of their manufacturability thanks to additive manufacturing processes. Ensuring the fatigue resistance of the cellular material will by extension ensure the structural integrity of the overall structure itself. The optimization is performed by using the MMA optimizer [Svanberg(1987)] whereas the singularity phenomenon of the stress constraints is circumvented by using the qp-relaxation [Bruggi(2008)]. Both types of optimization framework are evaluated in term of their numerical performances and are compared to classical results generated by a regular stress-based topology optimization. Finally, the results are 3D-printed to assess for their manufacturability. [less ▲]

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See detailSharing good practices in physical education to promote physical activity, wellness and health
Bonni, Jérémy ULiege; Cloes, Marc ULiege

Poster (2017, September 15)

The Wallonia-Brussels Federation is about to overhaul its education system, which will directly affect teacher training. Under the “Pact for Excellence in Education”, a group of experts – the Consortium ... [more ▼]

The Wallonia-Brussels Federation is about to overhaul its education system, which will directly affect teacher training. Under the “Pact for Excellence in Education”, a group of experts – the Consortium “Physical Activities, Well-Being and Health” – drawn from the 12 French-speaking institutions training PE teachers (universities and colleges) has been mandated by the Ministry of Education to design devices and tools aiming at implementing the new common core curriculum that is under construction. Good practices have been identified then described in information sheets common to the different consortiums of the PEE and listed in a table that cross-references the 6 dimensions of physical activity at school (Snyers et al., 2014) and the 20 objects of teaching-learning in health education (Turcotte et al., 2011). These good practices are meant to be shared later within a community of practice. This paper provides a description of one of these information sheets in order to illustrate the methodology applied in this project. [less ▲]

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See detailIdentification of Signaling Pathways Regulating Beta Cell Regeneration in Zebrafish
Massoz, Laura; Bergemann, David ULiege; Lavergne, Arnaud ULiege et al

Conference (2017, September 15)

Diabetes is becoming a leading health issue worldwide. It occurs under insulin resistance/deficiency and when insulin-producing pancreatic beta-cell mass is dramatically reduced. Besides therapeutic ... [more ▼]

Diabetes is becoming a leading health issue worldwide. It occurs under insulin resistance/deficiency and when insulin-producing pancreatic beta-cell mass is dramatically reduced. Besides therapeutic strategies to preserve beta-cell mass and function and improve insulin treatments, beta-cell replacement constitutes a promising alternative to replenish the pancreas with functional beta-cells. Beta-cell neogenesis can be achieved from different pancreatic cell types leading to the hope that triggering regeneration could be harnessed in future therapies. Still, mammals show limited regenerative capabilities, making difficult the study of these mechanisms. In contrast, zebrafish is extensively used for regeneration studies notably of beta-cells. We recently showed that the adult zebrafish ducts display characteristics of embryonic pancreatic progenitors that give rise to beta-cells in physiological and induced diabetic condition*. To better understand the molecular mechanisms underlying this potential, genes and signaling pathways regulated in the zebrafish pancreatic ducts after beta-cell ablation have been identified by transcriptomic profiling. For functional studies, we have developed an assay using 7-20 days old larvae to investigate the role of selected candidate pathways in beta-cell regeneration with pharmacological inhibitors/activators and by transgenic overexpression of candidate signaling factors. These results should provide new hints to help improve regenerative competences in mammals. [less ▲]

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See detailChanges in a metacognitive heuristic in amnesia
Thonnard, Adeline ULiege; Geurten, Marie ULiege; Willems, Sylvie ULiege

Poster (2017, September 15)

Amnesic patients rely predominantly on familiarity for recognition. This familiarity is thought to be based on processing fluency. However whether amnesic patients use normally this metacognitive ... [more ▼]

Amnesic patients rely predominantly on familiarity for recognition. This familiarity is thought to be based on processing fluency. However whether amnesic patients use normally this metacognitive heuristic is not yet known. We used the Jacoby and Whitehouse (1989)’s illusion paradigm with 8 patients with severe memory impairments and 16 matched control. We found a fluency effect, with more “old” responses being given to matched-prime test words than to mismatched-prime test words. In addition, we replicated the effect of modality (Westerman et al., 2002) in the control group. The fluency induced the recognition illusion, but only when there was a match between study and test sensory modality. However, this modality effect seems limited to control participants. Amnesic patients seem unable to disregard fluency when there was a shift in the sensory modality of the study and test stages. Overall, these findings support the notion that amnesic patients did not modulate their use of the fluency heuristic in situations where fluency is judged non-diagnostic of prior exposure by healthy participants. On the whole, these findings suggest that processing fluency can constitute a cue for recognition decision in amnesia. However, this influence is not direct and is subject to metamemorial belief changes. [less ▲]

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See detailMusic in the Operating Room
XHAUFLAIRE, Gaël ULiege; Albert, Louisa; Gengoux, Monique

Poster (2017, September 15)

Listening to music during surgery has a subjective benefit to patients under local anesthesia. Its setting up during quiet routine oculoplastic surgery is easy and inexpensive. When subject to some ... [more ▼]

Listening to music during surgery has a subjective benefit to patients under local anesthesia. Its setting up during quiet routine oculoplastic surgery is easy and inexpensive. When subject to some elementary precautions, there is no increased risk. [less ▲]

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See detailPublic spaces, Mediation, and Scales of Visibility : the case of the representation of rural workers in post-Mao China
Florence, Eric ULiege

Conference (2017, September 15)

Woven into complex social, political and cultural fields, migrants’ experiences and narrations of mobility and of how they fare outside their hometown, of how they are more or less successful in their ... [more ▼]

Woven into complex social, political and cultural fields, migrants’ experiences and narrations of mobility and of how they fare outside their hometown, of how they are more or less successful in their attempts to negociate social hierarchies and the formation of their identities often closely articulate with major social norms and values, as well as with processes of state formation. In this contribution, I argue that in studying how migrants’ agency are at once enabling and shaped by structural forces there is a need to focus on processes of “mediation” as these processes enable to think seriously the relationship between institutions/organisations , people and meanings . Focusing on processes of mediation enables to deal with how people’s subjectivities and agency are shaped in complex and never totalizing ways by the very institutions (medias) through which they mediate their experiences. By documenting specifically how migrant workers in post-Mao China mediate their experiences of social hierarchies and social mobility via their engagement with a specific form of media (popular literature), I stress the relevance of intertextuality, of the notion of “genre” (Bakhtin), of “publics” and draw from Roseberry’s use of “hegemonic frameworks” for whom hegemony is helfpful to study “the ways in which the words, images, symbols, forms, organizations, institutions, and movements used by subordinate populations to talk about, understand, confront, accommodate themselves to, or resist their domination are shaped by the process of domination itself”. For Roseberry, “What hegemony constructs, then is not a shared ideology, but a common material and meaningful framework for living through, talking about, and acting upon social orders characterized by domination”. According to this approach, establishing such a framework rests on “prescribed forms of procedures” or “prescribed forms for expressing both acceptance and discontent”, as well as anger, disillusion, aspirations, desires, etc. (Roseberry, 1994, p. 360-361). [less ▲]

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See detail5. Froment 2017: une récolte hâtive et étalée avec une qualité moyenne
Sinnaeve, Georges; Gofflot, Sébastien; Chandelier, Anne et al

in Bodson, Bernard; Watillon, Bernard (Eds.) Livre Blanc Céréales (2017, September 14)

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See detailExecutive functions in normal aging: the mediating effect of processing speed and attentional system
Gilsoul, Jessica ULiege; Simon, Jessica ULiege; Collette, Fabienne ULiege

Poster (2017, September 14)

Objective The normal aging is associated with decrease in executive functioning efficiency. However, the source of these cognitive difficulties could reside in some factors that are not executive per se ... [more ▼]

Objective The normal aging is associated with decrease in executive functioning efficiency. However, the source of these cognitive difficulties could reside in some factors that are not executive per se. Therefore, this present study is aimed at determining whether speed of processing and attentional variables would mediate the effect of age on the executive functioning. Participants and Methods Young (n = 104) and old (n = 63) participants were enrolled and carried out a large battery made of 21 executive (inhibition, shifting, working memory updating, and double task coordination), attentional (phasic alertness, selective attention, and sustained attention), and processing speed tasks. Based on Baron & Kenny’s recommendations (1986), mediation models of the age effect on the executive functioning were carried out with processing speed and attentional system taken as mediators. Results Selective attention significantly mediated the effect of age on working memory updating [􀇻R2 = 7%, p < .001]. Moreover, processing speed significantly mediated the effect of age on shifting [􀇻R2 = 7%, p < .001], working memory updating [􀇻R2 = 5%, p < .001], and double task coordination [􀇻R2 = 14%, p < .001]. Conclusions The mediating effect of age on most of the executive functions by measures of processing speed is in agreement with the literature showing a major influence of the slowdown of the processing speed on cognition (Salthouse, 1992; 2000; 2005). The age effect on inhibition did not seem to be mediated neither by the attentional variables nor the speed variables, which is in accordance with Zacks & Hasher’s hypothesis (1988). According to these authors, inhibition would be the first cognitive function to decline with age. [less ▲]

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See detailToward discovery of novel key genes for pancreatic beta cell regeneration in zebrafish
Carril Pardo, Claudio Andrès ULiege; Bergemann, David ULiege; Massoz, Laura ULiege et al

Poster (2017, September 14)

Diabetes is becoming a leading health issue worldwide. It occurs under insulin resistance/deficiency and when insulin-producing pancreatic beta-cell mass is dramatically reduced. Besides therapeutic ... [more ▼]

Diabetes is becoming a leading health issue worldwide. It occurs under insulin resistance/deficiency and when insulin-producing pancreatic beta-cell mass is dramatically reduced. Besides therapeutic strategies to preserve beta-cell mass and function and improve insulin treatments, beta-cell replacement constitutes a promising alternative to replenish the pancreas with functional beta-cells. Several observations of pancreatic cell plasticity has led to the hope that triggering beta-cell regeneration within the pancreas could be harnessed in future therapies. Still, mammals show limited regenerative capabilities, making difficult the study of these mechanisms. In contrast, zebrafish is extensively used for regeneration studies notably of beta-cells. We recently showed that the adult zebrafish ducts display characteristics of embryonic pancreatic progenitors that can give rise to beta-cells in physiological and induced diabetic condition*, and we determined the transcriptomic profile of zebrafish pancreatic ducts during beta-cell regeneration. To identify new genes crucial for beta-cell regeneration we plan to investigate the role of about 10 selected candidate genes by analyzing invalidating mutations created by CRISPR/Cas9. Their effect on beta-cell regeneration will be studied in 7-20 old larvae which we have established as experimental platform for functional studies. This project should help decipher the molecular mechanism of beta-cell regeneration. [less ▲]

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See detailModélisation des mécanismes psychologiques du processus de radicalisation
Garcet, Serge ULiege

Conference (2017, September 14)

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Peer Reviewed
See detailThe artistic patronage of Cardinal Charles II de Bourbon (1433-1488)
Laruelle, Anne-Sophie ULiege

Conference (2017, September 14)

As one of the most important political and religious figures of the mid-fifteenth century, Charles II de Bourbon (1433-1488) has not received the attention he deserves. Charles, archbishop of Lyon (1446 ... [more ▼]

As one of the most important political and religious figures of the mid-fifteenth century, Charles II de Bourbon (1433-1488) has not received the attention he deserves. Charles, archbishop of Lyon (1446), was made cardinal by the pope Sixtus IV in 1476. He was also an important courtier, and a confidant of King Louis XI of France, to whom he was related by marriage. Charles was present at the interview of Kings Louis XI and Edward IV of England in 1475 and in the signature of the peace treaty concluded between them, which formally ended the Hundred Years’ War. Among other posts, Charles held the governorship of Paris and was the head of the King’s Council. Grandson of John the Fearless and cousin to Charles the Bold, he also bore numerous connections with the Burgundian Court and the Southern Netherlands. This paper aims at re-appreciating the artistic patronage of the wealthy cardinal, in spite of the difficulties raised by the paucity of surviving artworks he commissioned. Charles was indeed an important patron, who founded a splendid funerary chapel in Lyon Cathedral, and had the archiepiscopal palace of Lyon built. The cardinal owned a lot of exceptional manuscripts, sculptures and tapestries. Due to his position, Charles may have influenced tastes of Louis XI for the arts, but also the future king Charles VIII’s (Charles de Bourbon was, along with Joan of Valois, Duchess of Bourbon and Edward of Westminster, godparent of the dauphin in 1470).Particular attention will be paid to his collection of tapestries, which have never received detailed analysis. Charles II de Bourbon’s arms (motto, initials, and his device of a flaming sword) appear on only three pieces today: “The Adoration of the Magi”, “The Three Coronations” (both preserved in Sens cathedral), and a scene from the “Story of Hercules” (Mobilier National, Paris). Woven with extremely high quality, probably in the Southern Netherlands, the cardinal’s tapestries are undoubtedly among the finest and most expensive pieces of the 15th century. [less ▲]

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See detailFrom Metabolomics Study of Age-Related Macular Degeneration (AMD) to the Development of New Pyruvate Dehydrogenase Kinase Inhibitors (PDK)
Arslan, Deniz ULiege; Schoumacher, Matthieu ULiege; Pirotte, Bernard ULiege et al

Poster (2017, September 14)

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly population of industrialized countries. This blindness results from the deterioration of the macula, a small part of ... [more ▼]

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly population of industrialized countries. This blindness results from the deterioration of the macula, a small part of the retina specialized for the high-acuity vision. Exudative AMD, called “wet”, is characterized by the formation of new blood vessels growing under the retina according to a process named choroidal neovascularization (CNV). Currently, the aetiology and pathogenesis of AMD remain unclear. Nevertheless, a recent metabolomics study performed on the serum of “wet” AMD patients and on a CNV murine model, that mimics the effect of “wet” AMD, have demonstrated that lactate level is clearly involved in the severity of the pathology as well as the relationship between lactate, CNV and AMD [1]. According to this result, we suggest a new therapeutic approach of AMD based on the normalization of blood lactate level. The modulation of the lactate plasma concentration by treatment of the animals with synthetic compounds and more specifically Pyruvate Dehydrogenase Kinase (PDK) inhibitors significantly decrease the CNV. PDK and its four isoforms (PDK1-4) regulate the activity of the pyruvate dehydrogenase complex (PDH), a mitochondrial enzyme that plays a major role in the metabolic pathway of glucose, by reversible phosphorylation. Starting from these results, development of new PDK inhibitors could open the way to innovative treatment opportunities in AMD disease. Different analogues of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide (fig.1) have been already synthetized and pharmacological evaluation is currently in progress. According to the results obtained, various pharmacomodulations will be investigated. [less ▲]

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See detail2. Variétés
Meza Morales, Walter ULiege; Jacquemin, Guillaume; Dumont, Benjamin ULiege et al

in Bodson, Bernard; Watillon, Bernard (Eds.) Livre Blanc Céréales (2017, September 14)

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See detail1. Implantation des cultures
Eylenbosch, Damien ULiege; Meza Morales, Walter ULiege; Monfort, Bruno et al

in Bodson, Bernard; Watillon, Bernard (Eds.) Livre Blanc Céréales (2017, September 14)

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See detailLes documents d'urbanisme. Vers quel typologies de représentation sous le paradigme du BIM ?
Boutemadja, Abdelkader ULiege

Conference (2017, September 14)

Sous le nouveau paradigme du BIM et du SIG 3D, quel typologies de représentation graphique doivent adopter les documents d'urbanisme. Il s'agit d'une reflexion qui donne à entrevoir les possibilités de ... [more ▼]

Sous le nouveau paradigme du BIM et du SIG 3D, quel typologies de représentation graphique doivent adopter les documents d'urbanisme. Il s'agit d'une reflexion qui donne à entrevoir les possibilités de représentation qu'offrent les nouvelles technologies. [less ▲]

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See detailDevelopment of SERS nanosensors for the detection of small bioactive molecules by cellular analysis in complex matrices: Application to dopamine
Dumont, Elodie ULiege; De Bleye, Charlotte ULiege; Cailletaud, Johan ULiege et al

Conference (2017, September 13)

This communication reports the different steps undertaken in order to develop a new Surface-Enhanced Raman Scattering (SERS) nanosensor for the quantification of dopamine in the culture medium of PC-12 ... [more ▼]

This communication reports the different steps undertaken in order to develop a new Surface-Enhanced Raman Scattering (SERS) nanosensor for the quantification of dopamine in the culture medium of PC-12 cells. First, the synthesis of the SERS substrate, gold nanoparticles, and its characterization. Then the development of the method with the help of a design of experiments and the demonstration of the specificity of the method over other structurally related catecholamines. And finally, the implementation of the method on the culture medium of PC-12 cells, on an HEPES buffer having served to wash the cells and on the PC-12 cells. [less ▲]

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See detailHow to distinguish between nouns and classifiers in Binominal Naming Constructions? Answers from two Western Amazonian languages
Van linden, An ULiege; Rose, Françoise

Conference (2017, September 13)

Western Amazonian languages stand out in showing classifiers that – in addition to the well-established classifier environments – also appear as derivational devices on nouns (Payne 1987; Aikhenvald 2000 ... [more ▼]

Western Amazonian languages stand out in showing classifiers that – in addition to the well-established classifier environments – also appear as derivational devices on nouns (Payne 1987; Aikhenvald 2000; Seifart & Payne 2007). Since classifiers are commonly assumed to originate in nouns (Aikhenvald 2000), classifier languages confront us with an analytical problem in the domain of Binominal Naming Constructions (BNCs), i.e. how to distinguish between the derivational use of classifiers on nouns (1)-(2) and noun-noun compounds (3)-(4). The present paper addresses this problem on the basis of primary data collected on Harakmbut (isolate, Peru), e.g. (1) and (3), and Mojeño Trinitario (Arawak, Bolivia), e.g. (2) and (4), two unrelated (and not in contact) Western Amazonian languages. While Mojeño Trinitario will be shown to be a multiple classifier language with an extensive set of classifiers, Harakmbut turns out to show (a small set of) classifiers only, in fewer environments. Yet, both languages will appear to behave strikingly similarly in the domain of BNCs. (1) classifier-derived nouns in Harakmbut a) siro-pi metal-CLF:stick ‘knife’ (cf. Hart 1963: 1) b) siro-pu’ metal-CLF:cylindrical;hollow ‘metal tube’ (cf. Hart 1963: 1) (2) classifier-derived nouns in Mojeño Trinitario a) yuk(u)-pi fire-CLF:long;flexible ‘candle’ b) wray(u)-'a chicken-CLF:oval ‘chicken egg’ (3) noun-noun compounds in Harakmbut a) ndumba-kuwa forest-dog ‘bush dog’ (Helberg 1984: 252; Tripp 1995: 194) b) äwït-ku giant.otter-head ‘giant otter’s head; person with giant otter’s head’ (4) noun-noun compounds in Mojeño Trinitario a) mari-chóchoku stone-river.bank ‘stony riverbank’ b) paku-miro dog-face ‘dog’s face; person with dog’s face’ In this paper, we will discuss how noun-classifier derivation compares to noun-noun compounding at the phonological, prosodic, semantic and syntactic levels in both Harakmbut and Mojeño Trinitario. For example, noun-noun compounds consist of clear “Thing-roots” (Haspelmath 2012) in both languages, with one element being the morphosyntactic and semantic head. In noun-CLF formations, however, classifiers do not really denote a “thing”, but rather a shape or quality; they do not contain a head. As a factor bearing on this analytical problem, we will show that in both languages the noun/classifier distinction is blurred by the fact that there is a class of nouns that share many features with the canonical classifiers. In both languages, these nouns refer to parts of entities, such as bodyparts, cf. (3b) and (4b), or plant parts. Morphologically, these are bound roots, which require affixation to obtain independent nominal status, specifically possessor prefixes in Mojeño Trinitario and (semantically empty) nominalizing prefixes in Harakmbut. Interestingly, in both languages such N-N compounds as (3b) and (4b) can be used as endocentric compounds in their literal sense, but they can also be used exocentrically to refer to a person whose (physical) characteristics resemble those of the referent of the endocentric compound. In Mojeño Trinitario, such exocentric uses take determiners for human referents, whereas neither component noun refers to a human entity (Harakmbut lacks any formal indication for such uses). More generally, we will examine to what extent these bound nouns can be analysed as incipient classifiers, and formulate diachronic hypotheses informed by our analysis of BNCs. [less ▲]

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See detailComparaison de l'impact de deux méthodes d'apprentissage sur la sécurité d'administration des médicaments : stages cliniques versus simulation
Servotte, Jean-Christophe ULiege; Galerin, Catherine ULiege; Ghuysen, Alexandre ULiege et al

Conference (2017, September 12)

Introduction Drug administration is the act nurses most frequently do. However, 50% of errors occur during administration. The damage these errors causes to patients, results in excess mortality rates and ... [more ▼]

Introduction Drug administration is the act nurses most frequently do. However, 50% of errors occur during administration. The damage these errors causes to patients, results in excess mortality rates and health care costs, hence leading to a major public health problem. Therefore, it is advisable to consider the training of future nurses on the practice of this delicate act. The objective of this study is to evaluate the impact of teaching by simulation combined with the internship on the safety administration of intravenous drugs by nursing students, compared to just the internship alone. Material and method A selection of 99 students from the bachelors’ block two of the Namur-Liege-Luxembourg Higher Institute of Nursing met the inclusion criteria under consideration. They were divided into two groups, one experimental group which participated in a simulation session and a control group, the latter did not participate in the simulation session. At the start of the research, all students were assessed by an objective structured clinical examination (OSCE) with the theme of modifying infusion and syringe flow rates. They were also asked to complete a questionnaire concerning their knowledge and self-efficacy feeling related to drug administration. The experimental group then participated in the simulation sessions. The experimental group and the control group also went into four weeks of training in medical or surgical services before participating in the second stage of the study. The latter consisted of the same tests and questionnaires as stage one of the study. The evolution of the results of the two groups was first observed separately before being compared. Results The majority of the results shows that the simulation improves, in a way significantly more important than the clinical course, the acquisition of skills and knowledge, as well as the feeling of self-efficacy in drug administration. On the other hand, the assessment of the level of stress linked to drug administration and the professional attitude evaluated during the OSCE were not significantly more improved by the simulation than by the training alone (stress: p-value = 0.8269, professional attitude = 0.9857). Conclusions For the students in the experimental group, the simulation showed a positive impact on the skills, knowledge and feeling of self-efficacy associated with drug administration. Changes and continuation of the study would make it possible to go further in the generalization of results, in the evaluation of learning outcomes, and to attest to their sustainability. [less ▲]

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See detailFrom seed to vegetable and from vegetable to seed : constructing a right to existence
Hecquet, Corentin ULiege

Conference (2017, September 12)

Detailed reference viewed: 25 (2 ULiège)
See detailLiDAR aérien et autres nuages de points pour la cartographie multi-échelles
Poux, Florent ULiege; Neuville, Romain ULiege; Kasprzyk, Jean-Paul ULiege et al

Conference (2017, September 12)

Utilisation de nuage de points pour la cartographie 3D multi-échelles. Exemples d'utilisation et définition de workflows pour assurer l'interopérabilité lors de la fusion de données issues de différents ... [more ▼]

Utilisation de nuage de points pour la cartographie 3D multi-échelles. Exemples d'utilisation et définition de workflows pour assurer l'interopérabilité lors de la fusion de données issues de différents capteurs. [less ▲]

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See detailSampling only 10 μL of whole blood to study the bioavailability of itraconazole formulations in rats
Kok, Miranda ULiege; Thiry, Justine ULiege; Evrard, Brigitte ULiege et al

Conference (2017, September 12)

Background Volumetric absorptive microsampling (VAMS) offers a unique opportunity to collect small and accurate quantities of biological fluids. This sampling technique is of great interest for volume ... [more ▼]

Background Volumetric absorptive microsampling (VAMS) offers a unique opportunity to collect small and accurate quantities of biological fluids. This sampling technique is of great interest for volume-limited samples and for the collection of multiple samples from the same animal. This serial sample collection may reduce the number of required study animals, thereby fulfilling the three Rs rule (refine, reduce, replace). Here, we demonstrate the applicability of VAMS to study the bioavailability of drug formulations in rats. Methods Four itraconazole-containing formulations were successively administered to rats with a wash-out period of one week. VAMS was used to collect 14 whole blood samples of only 10 μL each within a time frame of 48 hours after administration of the different drug formulations. Particular attention was paid to sample preparation and stability. The extraction of itraconazole and its main metabolite hydroxy-itraconazole was optimized to provide a high recovery and minimal matrix effects. A developed and validated LC–MS/MS method was used for the quantification of the two compounds. Pharmacokinetic profiles for the different formulations were constructed and compared. Results The stability of itraconazole and hydroxy-itraconazole in dried VAMS samples of whole rat blood could not be guaranteed for more than a day when the samples were stored at room temperature. However, samples were stable for at least two weeks when stored at -80°C after sample preparation. Differences in pharmacokinetic profiles were observed for the tested drug formulations. Whole blood concentrations of itraconazole and its main metabolite were significantly higher after administration of three in-house produced formulations compared to concentrations obtained with a commercially available product. Moreover, these in vivo results could be partly related to in vitro dissolution rates of the various formulations. Conclusions VAMS is an attractive approach for bioavailability studies. Due to the low blood volumes per sampling point, the same rats can be used to compare various drug formulations. Therefore, the number of required animals can be drastically reduced. Moreover, this helps to suppress the inter-individual variability and strengthens the validity of results. [less ▲]

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See detailCitoyens dans un système handicapant : le cas des outsiders.
Fontaine, Sébastien ULiege

Conference (2017, September 12)

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See detailInfluences of feeding behaviour and forage quality on diurnal methane emission dynamics of grazing cows
Blaise, Yannick ULiege; Andriamandroso, Andriamasinoro ULiege; Heinesch, Bernard ULiege et al

in Berckmans, Daniel; Keita, Keita (Eds.) Precision Livestock Farming ‘17 (2017, September 12)

This study aimed to evaluate diurnal methane (CH4) emission dynamics of grazing cattle and highlight their relationships with biotic factors such as the feeding behaviour as well as seasonal changes in ... [more ▼]

This study aimed to evaluate diurnal methane (CH4) emission dynamics of grazing cattle and highlight their relationships with biotic factors such as the feeding behaviour as well as seasonal changes in pasture characteristics. Existing methods to assess grazing ruminants’ daily CH4 emissions provide useful insights to investigate mitigation strategies relying on feeding and genetic selection. Nonetheless such methods based on tracer gases (SF6) or feeding bins equipped with sniffers (e.g. GreenFeed) can hardly cover diurnal CH4 emission fluctuations which can influence the accuracy of total CH4 production estimations. Previous studies in barns showed that emission dynamics strongly vary during post feeding time, leading to a possible bias in estimates of daily CH4 emissions as high as 100%. To investigate whether such fluctuations are also taking place on pasture, a portable device was designed with infrared CH4 and CO2 sensors measuring concentrations in the exhaled air at a high sampling rate (4 Hz). Six grazing dry red-pied cows were equipped with the device and motion sensors during runs of 24h to monitor CH4 and CO2 emissions and detect their feeding behaviours (grazing, rumination and other behaviours), respectively. This experiment was performed in summer and fall in order to cover seasonal changes in pasture forage quality. Methane emission was estimated from the CH4:CO2 concentration ratio and the metabolic CO2 production of the cows. As for barn studies, variations were observed in total daily CH4 emission due to the seasons and diurnal variations were also observed due to animal behaviours. Relationships between animal feeding behaviour and CH4 emissions patterns on pasture were also unravelled. [less ▲]

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See detailManaging and authenticating non-institutional users in Alma: two experiences
Brownlie, Helen; De Groof, Robert ULiege; Renaville, François ULiege

Conference (2017, September 12)

The management of patron information within Alma is primarily reliant on two systems – the creation and updating of patron information by an external system such as student management or HR systems or ... [more ▼]

The management of patron information within Alma is primarily reliant on two systems – the creation and updating of patron information by an external system such as student management or HR systems or internally within Alma itself. A recent survey of the Alma community indicated the majority of institutions utilize a mixture of these external and internal processes. In addition to providing access to affiliated staff and students more than 89% of institutions responded that they provided user accounts to non-affiliated users such as the general public, members of other academic institutions, alumni, etc. Providing authenticated access to library services for the latter group relies heavily on Alma for password management. This presentation will outline the processes in place at the University of Otago and at the University of Liège for managing and authenticating non-institutional users and the possible effect of Ex Libris' proposed changes to internal authentication. [less ▲]

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See detailInnovation et créativité : un nouvel objet d’apprentissage en formation
Hausman, Matthieu ULiege; Vincent, Coline

Conference (2017, September 12)

Comment amener les futurs-enseignants à innover pour faire face à leurs futurs défis professionnels ? Depuis deux ans, notre formation initiale propose un dispositif ayant pour visée principale de ... [more ▼]

Comment amener les futurs-enseignants à innover pour faire face à leurs futurs défis professionnels ? Depuis deux ans, notre formation initiale propose un dispositif ayant pour visée principale de stimuler la créativité des étudiants et, par extension, celle de leurs futurs élèves. Actuellement, la créativité n’apparait pas explicitement dans le référentiel de compétences des enseignants en Belgique francophone (2000). Nous y voyons néanmoins une compétence professionnelle indispensable à développer à l’heure où l’innovation est aussi au centre des préoccupations des acteurs de l’éducation. Un processus créatif est donc mené au sein d’activités visant à la fois une meilleure compréhension du concept et son appropriation en tant que démarche fonctionnelle. Les futurs-enseignants y développent des pistes d’innovations pédagogiques en référence aux étapes d’un modèle inspiré du Creative Problem Solving (Osborn et Parnes, 1926). Pour la seconde année consécutive, c’est donc la capacité à innover de nos étudiants que nous souhaitons développer. La créativité étant le moyen choisi pour y parvenir, l’hypothèse principale que nous allons vérifier suite aux ajustements qui ont suivi notre première analyse (2015-2016) est la suivante : Le dispositif permet aux étudiants de faire évoluer leurs représentations du métier en y intégrant le processus créatif comme démarche fonctionnelle. [less ▲]

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See detailLa régulation pédagogique comme vecteur de valeurs professionnelles - Le cas d’étudiants de BAC 1, futurs enseignants
Hausman, Matthieu ULiege

Conference (2017, September 12)

En tant que jeune maître-assistant chargé de la formation pédagogique des futurs enseignants du secondaire à la Haute Ecole de la Ville de Liège (Belgique), j’accorde beaucoup d’importance à la ... [more ▼]

En tant que jeune maître-assistant chargé de la formation pédagogique des futurs enseignants du secondaire à la Haute Ecole de la Ville de Liège (Belgique), j’accorde beaucoup d’importance à la construction par les étudiants de savoirs et compétences solidement ancrés et utiles à l’exercice de leur futur métier. Il y a deux ans, ma participation au Master de spécialisation en pédagogie de l’enseignement supérieur (Formasup, Université de Liège) m’a donné l’occasion d’analyser mes pratiques d’enseignement à la lumière de mes valeurs « constructivistes ». J’ai alors pu constater que le dispositif qui vise le développement de compétences de planification pédagogique par les étudiants de BAC1 n’était pas tout à fait en phase avec ces valeurs. Ce constat m’a amené à revoir le dispositif pour davantage solliciter l’engagement et la réflexion des étudiants par rapport aux « invariants opératoires » associés à la planification. Conformément à l’approche SoTL prônée par Formasup, j’ai mené une recherche en classe afin d’étudier les effets du dispositif régulé sur la qualité d’apprentissage et la motivation de mes étudiants. Cette recherche m’a permis de confirmer que le dispositif permettait effectivement aux étudiants de s’approprier les invariants opératoires de planification et, par le processus de contextualisation – décontextualisation – recontextualisation au cœur du dispositif, d’appliquer ceux-ci à des situations de plus en plus proches du futur contexte professionnel. La recherche a montré aussi que l’approche réflexive que je souhaitais voir mes étudiants adopter n’est pas encore suffisamment soutenue par le dispositif qui doit encore être amélioré à cet égard. [less ▲]

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See detailContent Working Group Report 2016-2017
Renaville, François ULiege; Varjabedian, Kathy

Conference (2017, September 11)

Report on the activities in 2016-2017 of the Content Working Group (previously Knowledge Base Advisory Board [KBAB]).

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See detailBuckling of steel plates at elevated temperatures: Theory of perfect plates vs finite element analysis
Maraveas, Chrysanthos ULiege; Gernay, Thomas ULiege; Franssen, Jean-Marc ULiege

in Proceedings of CONFAB'17 Conference (2017, September 11)

The local buckling capacity of fire exposed thin-walled steel cross sections is affected by the reduction in strength and stiffness due to elevated temperatures and the amplitude of the initial local ... [more ▼]

The local buckling capacity of fire exposed thin-walled steel cross sections is affected by the reduction in strength and stiffness due to elevated temperatures and the amplitude of the initial local imperfections. Several researchers have proposed design methods to calculate the capacity of the plates (i.e. web and flanges) that compose these steel members at elevated temperatures, but they used different shapes of steel plates (sides ratio a/b) and different amplitudes of local imperfections. This variability in hypotheses happens because there is no clear provision defining the numerical modeling procedure for fire design of steel plates in the codes (European or US). According to the theory of perfect plates, the critical load depends of the shape of the rectangular plate (e.g. the sides ratio a/b) and the corresponding buckling mode (number of half waves), the boundary and the loading conditions. This paper reviews the existing code provisions and compares the existing design models and their assumptions for thin-walled steel cross sections. Elements of the theory of perfect plates are presented. Parametric finite element analyses are then conducted on isolated steel plates at elevated temperatures to investigate the effect of the plate shape (a/b ratio) and imperfections (amplitude and number of half wave lengths). From the analysis, the governing parameter will be estimated (a/b vs imperfections) for simulation of isolated flanges and webs. Finally, recommendations for the numerical modeling of steel plates at elevated temperatures are proposed. [less ▲]

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See detailA tiny magic drawing board to track the penetration of magnetic flux in superconductors
Silhanek, Alejandro ULiege

Conference (2017, September 11)

Local polarization of a magnetic layer, a well-known method for storing information, has found its place in numerous applications such as the popular magnetic drawing board toy or the widespread credit ... [more ▼]

Local polarization of a magnetic layer, a well-known method for storing information, has found its place in numerous applications such as the popular magnetic drawing board toy or the widespread credit cards and computer hard drives. Here we experimentally show that a similar principle can be applied for imprinting the trajectory of quantum units of flux (vortices), travelling in a superconducting film (Nb), into a soft magnetic layer of permalloy (Py). In full analogy with the magnetic drawing board, vortices act as tiny magnetic scribers leaving a wake of polarized magnetic media in the Py board. The mutual interaction between superconducting vortices and ferromagnetic domains has been investigated by the magneto-optical imaging technique. For thick Py layers, the stripe magnetic domain pattern guides both the smooth magnetic flux penetration as well as the abrupt vortex avalanches in the Nb film. It is however in thin Py layers without stripe domains where superconducting vortices leave the clearest imprints of locally polarized magnetic moment along their paths. In all cases, we observe that the flux is delayed at the border of the magnetic layer. Our findings open the quest for optimizing magnetic recording of superconducting vortex trajectories. [less ▲]

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See detailWho are “the people” in populist rhetoric? The case of the “Front National” (FN) and the “Freiheitliche Partei Österreichs” (FPÖ)
Debras, François ULiege

Conference (2017, September 09)

In recent years, the “Front National” (FN) in France has claimed to be the “defender of the people” and “guarantor of their interests”. In 2017, the campaign slogan of Marine Le Pen, party leader and ... [more ▼]

In recent years, the “Front National” (FN) in France has claimed to be the “defender of the people” and “guarantor of their interests”. In 2017, the campaign slogan of Marine Le Pen, party leader and candidate in the presidential election, was “in the name of the people”. In Austria, the “Freiheitliche Partei Österreichs” (FPÖ) stood as the “voice of the oppressed majority”. The party is demanding “a direct democracy in order to let the people speak”. These elements lead us to question the notion of “the people”. How should we define “the people”? What reality does it refer to? What are the underlying political and ideological issues? Firstly, to answer this question, I aim to clarify the term “the people” in populist rhetoric. The FN and the FPÖ are often described as “far-right parties”. However, many scholars also refer to them as “populist parties”. These terms clearly need explaining. Secondly, this work will analyse the political discourse of the FN and the FPÖ. The focus will be on the political programmes and oral communication coming from their principal representatives. This analysis is discursive. It isn’t an examination of the work performed by party supporters or members (parliamentary work, action in local authorities, etc.). Apparently, the rhetoric from both parties is structured around two dichotomies: 1) the removal of social boundaries in favour of a people/elite opposition; 2) the affirmation of cultural boundaries in favour of an opposition between natives to a country and foreigners. I will explain why these notions of social and cultural boundaries have a prominent place in rhetoric in line with populist theory. The desire to suppress social boundaries, allows us to identity a first issue: sovereignty. The affirmation of cultural boundaries illustrates a second issue: unity. Finally, a third issue is transmitted through the notion of sovereignty and unity: identity. To conclude, I will return to the classification of the “Front National” and the “Freiheitliche Partei Österreichs” as “right-wing-populist” parties. I will end by answering the question: “who are ‘the people’”? This will explain why populist rhetoric responds to a feeling of unease within society and, more generally, within Western democracies. [less ▲]

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See detailExploring insulin resistance in migraine: a population-based study
Streel, Sylvie ULiege; Donneau, Anne-Françoise ULiege; Schoenen, Jean ULiege et al

Poster (2017, September 09)

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See detailUsing IPCAPS to identify fine-scale population structure
Chaichoompu, Kridsadakorn ULiege; Fentaw Abegaz, Yazew ULiege; Tongsima, Sissades et al

Poster (2017, September 09)

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See detailRound table. Quaternary Prevention(P4) or first do not harm.
Jamoulle, Marc ULiege; Widmer, Daniel; La Valle, Ricardo et al

Conference (2017, September 09)

Quaternary prevention (P4), born from a reflection on the doctor-patient relationship, began as an answer of family doctors facing overmedicalization. It aims to protect the patient or population against ... [more ▼]

Quaternary prevention (P4), born from a reflection on the doctor-patient relationship, began as an answer of family doctors facing overmedicalization. It aims to protect the patient or population against the danger of medicine. Harmful effects can appear with preventive activities (example: prostate cancer screening by PSA) as well as by therapeutic interventions (example: disruptive medicine). P4 promoted by the World Organization of Family Doctors (WONCA) is practiced in different ways around the world through the activity of the WONCA Special Interest Group on Quaternary Prevention and Overmedicalisation (P4&O). There are multiple initiatives and backgrounds of P4. All these multiple initiatives that lead to P4 have their origin in denouncing the inadequacies of the Hegemonic Medical Model and the excesses perpetrated in the pursuit of profit. There are many schools of thought that try to solve this situation, such as "Medicines Based on ..." These contributions are valuable but usually point to a single dimension of the problem so they do not change the situation too much. The P4, however, have understood the centrality of the political and economic dimensions and, that is why, P4 has become a movement. P4 has understood that the root causes far exceed the limits of medicine, have understood that the problem includes ethical, political, economic and epistemological aspects of medicine. It is for this reason that the definition of P4 has shifted to the function of foundational idea since the movement that has been generated around this concept has surpassed this initial definition centered in a, yet complex, but still medical vision. P4 has understood that a new model of medicine and a new pact with society is necessary. P4 is a counter-hegemonic movement with predominant development in peripheral countries. This movement includes many other perspectives developed in the central countries but is the only one that has an ideological position that discusses the current paradigm of medicine that legitimates the same causes that give rise to P4, proposing to think a new way of practice the medicine that includes Ethical values, other forms of knowledge and the return to human medicine for humans with place for uncertainty, compassion, the encounter between people and non-commodified. Justice in health care is a central aspect of this new way of conceiving the medicine that we propose. Remember what Rudolf Virchow said in the nineteenth century "Physicians are the natural advocates of the poor and social problems fall largely under their jurisdiction. Medicine is a social science, and politics is nothing more than medicine in large scale". We must reformulate our contract with society and for this we must be very clear that our loyalty must always be with the sick, the poor and those who are weak. For this new contract we must also take into account the magnitude of the power that has been given to us and to live up to such responsibility. In the Rio manifesto (2016) we propose to “Avoid and denounce the naturalization of: hunger, exclusion, manipulation, inequality, violence, racism, exploitation, which harm health more than "diseases"” . There is a better and fairer world, let's fight to get it! More about P4 on www.ph3c.org/p4 [less ▲]

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See detailInscription, iteration, transformation
De Winter, Mélanie ULiege; Slomian, Cynthia ULiege

Conference (2017, September 09)

In “Knowledge in policy”, Freeman and Sturdy propose a phenomenology with the aim of “knowing knowledge” (Freeman & Sturdy, 2014, p. 2). Knowledge can have different forms called “inscribed”, “embodied” ... [more ▼]

In “Knowledge in policy”, Freeman and Sturdy propose a phenomenology with the aim of “knowing knowledge” (Freeman & Sturdy, 2014, p. 2). Knowledge can have different forms called “inscribed”, “embodied” and “enacted”. This framework is presented as a way to categorize and describe the form, the circulation and the transformation of knowledge in policymaking. In this paper, we intend to focus on inscribed knowledge, and particularly on documents conceived as essential artefacts of public policies (Freeman & Maybin, 2011). Freeman and Sturdy defined inscribed knowledge as “written down in texts, or represented in pictures and diagrams; or it may be incorporated into instruments, tools and machines, among other things”(Freeman & Sturdy, 2014, p. 10). This form of knowledge is particularly “stable”, “easily reproducible” and “highly mobile” so “it can be communicated or made available to many different individuals separated in time and/or space”(Freeman & Sturdy, 2014, p. 10). This statement draws from works in sociology of science and technology. These works, especially Latour’s (1987) studies of the laboratory work and Law's (1986) analysis of control at distance particularly emphasize the power of inscriptions in constraining social action over time and space. Through the analysis of the implementation of two policy plans in the Belgian healthcare sector, we question and put the role of inscriptions in perspective with moments of enactment, by focusing on meetings. We intend to show that some documents are crucial at particular moments and lose value at other moments. In the same vein, we also aim to show the importance of iteration, moments, duration, and rhythms in public action. By doing so, we show how the public policy itself is transformed through time, documents and meetings. We address this issue by drawing on two PhD researches focusing on the devising and implementation of the policy plans mentioned above. By relying on interviews, observations and document analysis, we describe the policy strategies inscribed in documents as well as key moments of both documents’ trajectories. In so doing, we emphasise that documents and meetings articulate with each other in an iterative process that in turn transforms the public policies themselves. [less ▲]

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See detailTowards a web-based platform for plotting, visualizing and enriching diachronic semantic maps: With a case study on the Greek and Egyptian temporal semantic field
Georgakopoulos, Athanasios ULiege; Polis, Stéphane ULiege

Conference (2017, September 09)

Semantic maps aim at detecting cross-linguistic regularities and recurrent patterns in semantic structure (Haspelmath 2003). This method was initially applied to the grammatical domain, mostly in a ... [more ▼]

Semantic maps aim at detecting cross-linguistic regularities and recurrent patterns in semantic structure (Haspelmath 2003). This method was initially applied to the grammatical domain, mostly in a synchronic perspective (with some exceptions, see, e.g., van der Auwera & Plungian 1998). Recent research, however, has drawn attention to the lexical domain, showing that the model can also include lexical semantics (see, e.g., François 2008). Intimately related to the semantic map method has been the issue of finding appropriate ways of creating those maps and of capturing visually the semantic regularities. Up until recently, the maps were plotted and drawn manually. However, Regier et al. (2013) showed that a good approximation algorithm exists for inferring semantic maps based on polysemy data. Elaborating on their method, this paper aims to demonstrate that information about the directionality and the weight of the edges can be automatically added, thereby providing valuable information regarding the paths of semantic extensions and their frequency. In order to illustrate the method, we take the example of the semantic extension of time-related lexemes (e.g. TIME, HOUR, SEASON, DAY) in Ancient Greek (8th – 1st c. BC) and Ancient Egyptian – Coptic (26th c. BC – 10th c. AD). Both languages give access to significant diachronic material, allowing us to trace long term processes of semantic change. The results of our diachronic investigations are then checked against databases giving information on synchronic polysemies (e.g., List et al. 2014). In doing so, we also assess the adequacy of the use of polysemy as a tool to investigate semantic change. [less ▲]

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See detailA method for hybrid fire testing: Development, implementation and numerical application
Sauca, Ana ULiege; Mergny, Elke ULiege; Gernay, Thomas ULiege et al

in Gillie, Martin; Wang, Yong (Eds.) Proceedings of ASFE 2017 Conference (2017, September 08)

Hybrid Fire Testing (HFT) is a technique that allows assessing experimentally the fire performance of a structural element under real boundary conditions that capture the effect of the surrounding ... [more ▼]

Hybrid Fire Testing (HFT) is a technique that allows assessing experimentally the fire performance of a structural element under real boundary conditions that capture the effect of the surrounding structure. To enable HFT, there is a need for a method that is unconditionally stable, ensures equilibrium and compatibility at the interface and captures the global behaviour of the analysed structure. A few attempts at conducting HFT have been described in the literature, but it can be shown, based on the analytical study of a simple one degree-of-freedom elastic system, that the considered method was fundamentally unstable in certain configurations which depend on the relative stiffness between the two substructures, but which cannot be easily predicted in advance. In this paper, a new method is introduced to overcome the stability problem and it is shown through analytical developments and applicative examples that the stability of the new method does not depend on the stiffness ratio between the two substructures. The new method is applied in a virtual hybrid test on a 2D reinforced concrete beam part of a moment resisting frame, showing that stability, equilibrium and compatibility are ensured on the considered multiple degree-of-freedom system. Besides, the virtual HFT succeeds in reproducing the global behaviour of the analysed structure. The method development and implementation in a virtual (numerical) setting is described, the next step being its implementation in a real (laboratory) hybrid test. [less ▲]

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See detailComparative fire analysis of steel-concrete composite buildings designed following performance-based and U.S. prescriptive approaches
Elhami Khorasani, Negar; Fang, Chenyang; Gernay, Thomas ULiege

in Gillie, Martin; Wang, Yong (Eds.) Proceedings of ASFE 2017 Conference (2017, September 08)

Performance-based structural fire design provides a rational methodology for designing modern buildings with cost-effective solutions. However, in the United States, fire design still largely relies on ... [more ▼]

Performance-based structural fire design provides a rational methodology for designing modern buildings with cost-effective solutions. However, in the United States, fire design still largely relies on design at the component level using prescriptive approaches. With performance-based approaches, there is an opportunity to benefit from increased flexibility and reduced cost in the design, but these advantages need to be explicitly described and disseminated to promote this shift in paradigm. In this paper, a comparative analysis is conducted on multi-story steel-concrete buildings designed following performance-based and U.S. prescriptive approaches. The steel-concrete composite structure allows taking advantage of tensile membrane action in the slab during fire, and therefore removing the fire protection on secondary beam elements. The nonlinear finite element software SAFIR is used to model the behavior of the buildings under the standard ASTM fire and a natural fire determined using the two-zone fire model CFAST. The numerical simulations show that performance-based design can be used to achieve the required level of safety currently enforced in the U.S. prescriptive guidelines, while providing an opportunity for cost reduction in fire protection material. [less ▲]

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