References of "Scientific congresses and symposiums"
     in
Bookmark and Share    
Full Text
See detailFrom the Hubble Space Telescope to Juno, unraveling the secrets of Jupiter's UV aurorae
Bonfond, Bertrand ULg

Conference (2015, May 19)

The successive generations of instruments on board the Hubble Space Telescope (HST) have revealed an increasing amount of details concerning the aurorae of Jupiter. Among the most striking results is the ... [more ▼]

The successive generations of instruments on board the Hubble Space Telescope (HST) have revealed an increasing amount of details concerning the aurorae of Jupiter. Among the most striking results is the finding that these aurorae are actually made of a multitude of components arising from a variety of processes, ranging from the local interaction of the Jovian moons with the magnetospheric plasma to solar-wind induced compression of the whole magnetosphere. In this presentation, I will review a few recent results obtained from Hubble Space Telescope observations. First, I will show how the morphology and the dynamics of the Ganymede footprint, i.e. the aurora on Jupiter created by the electromagnetic interaction between Ganymede and Jupiter, allowed us to infer the processes at play. Then, I will present results on the vertical profile of the auroral emissions and what they tell us about the acceleration of the electrons causing the auroral emissions. Furthermore, I will describe some of the short-timescale dynamics of the polar-most emissions, including their quasi-periodic nature. Finally, I will conclude with a short description of the expected outcome of the Juno mission, which will provide its first scientific results in fall 2016. [less ▲]

Detailed reference viewed: 55 (0 ULg)
See detailThe influence of lithology on the mechanical strength and porosity of terra-cotta, the case study of Marrakech region (Morocco).
El Boudour El Idrissi, Hicham ULg; Daoudi, Lahcen; Collin, Frédéric ULg et al

Poster (2015, May 19)

The ceramic pastes in Marrakech region are prepared on the base of six types of raw materials of different lithologies. Various products are manufactured. The production consists of cooking utensils ... [more ▼]

The ceramic pastes in Marrakech region are prepared on the base of six types of raw materials of different lithologies. Various products are manufactured. The production consists of cooking utensils (based on schist, colluviums, quartzose sand and silt), decoration products (based on argillite, washing residues and soil), vases and gourds products (based on schist and soil), tiles (based on silt decantation) and traditional dishes (based on soil and argillite). In this study we elaborate bricks from the different raw material and we evaluate some of their physical properties after firing at 1050°C. In particular we measure the porosity to water and the mechanical strength of all the fired bricks. The aim is to compare the final product quality according to the origin (lithology) of the clayey raw material of the ceramic pastes. Based on our experiments, the bricks of the lower compressive strength (CS) and of the lower flexural strength (FS) are those based on sand (CS = 39 MPa; FS = 7 MPa), on silt decantation (CS = 25 to 39 MPa; FS = 10 to 18 MPa), and on schist and colluviums (CS = 20 to 51 MPa; FS = 6 to 17 MPa). Those of the highest values are based on argillites (CS = 33 to 102 MPa; FS = 13 to 28 MPa). The other pastes are characterized by intermediate values. The porosity ranges between 5 to 27%. The bricks based on silt decantation have the greatest values (20 to 27%), whereas those based on argillite have the lower values (5 to 10%). Those physical properties are, in most cases, in agreement with the requested values of the bricks industry. We conclude that such raw materials have high perspective to manufacture structural products of high performance in mechanical strength and thermal insulation. [less ▲]

Detailed reference viewed: 19 (5 ULg)
Full Text
See detailScreening for interesting elicitors to protect wheat against Zymoseptoria tritici
Le Mire, Géraldine ULg; Siah, Ali; Fauconnier, Marie-Laure ULg et al

Conference (2015, May 19)

Plants face an array of biotic and abiotic stresses in their environment, making it necessary to use various chemical inputs to maintain satisfactory yield. Today, conventional agriculture is evolving ... [more ▼]

Plants face an array of biotic and abiotic stresses in their environment, making it necessary to use various chemical inputs to maintain satisfactory yield. Today, conventional agriculture is evolving towards more sustainable practices, out of respect for human health and the environment. Elicitors are considered as promising biological control tools and draw major interest in IPM strategies. These plant-immunity triggering compounds, also called “stimulators of plant natural defenses”, induce a general and systemic resistance in the plant to various diseases. Although numerous elicitors have already been identified and some of them reached the market since the late 1970s, further investigations are still required to better understand the mode of action of these molecules in the plant and ensure a consistent efficiency under various field conditions. Few elicitors have yet been successfully tested and formulated to protect crop plants such as wheat, which is cultivated over large areas in Europe. This study focuses on the screening of ten potential elicitor products of various origins and structures to protect winter wheat against the fungal pathogen Zymoseptoria tritici. Greenhouse trials were carried out to measure the ability of the different products to reduce disease foliar symptoms (necrosis, chlorosis and pycnidia). In addition, the phytotoxicity and biocide activities of these products were evaluated under greenhouse and laboratory conditions, respectively. The corresponding results will be presented and discussed with the perspective to choose the best elicitor candidates and to undertake investigations on the signaling pathway and the influence of environmental parameters on the elicitation capacity. [less ▲]

Detailed reference viewed: 33 (13 ULg)
See detailTuta absoluta (Lepidoptera: Gelechiidae) development on wild and cultivated plant species
Bawin, Thomas ULg; Dujeu, David ULg; Fagan, Maud ULg et al

Conference (2015, May 19)

The tomato leafminer, Tuta absoluta (Lepidoptera: Gelechiidae), is a widespread invasive species damaging economically important cultivated solanaceous crop plants, including tomatoes and potatoes. Little ... [more ▼]

The tomato leafminer, Tuta absoluta (Lepidoptera: Gelechiidae), is a widespread invasive species damaging economically important cultivated solanaceous crop plants, including tomatoes and potatoes. Little is known about the ability of this microlepidoptera to encounter and develop on alternative wild and agricultural plant species. These plants could provide refuges and have to be identified for more efficient integrated management strategies. In the present study, we assessed under laboratory conditions the ability of T. absoluta to develop on such plant species referred as potential hosts in the literature, including Solanaceae, Chenopodiaceae, Convolvulaceae, Fabaceae, and Malvaceae. For each plant species, fitness tests were performed in Petri dishes by isolating single individuals with excised leaf. We found that Solanum species allowed higher larval survivability and shorter development time (from egg to adult emergency) compared to the other plants. Non-solanaceous plants were not able to sustain T. absoluta larvae. Two choice behavioral assays performed in flying tunnels revealed that adult distribution and female oviposition did not differ between Solanum species, which were preferred to other tested solanaceous plants. These results appeared to be consistent with survival rates and development times. Because larval survivability depends on the female’s oviposition choice, the hypothesis that host plant choice is influenced by plant volatile organic compounds has to be tested. Volatile organic compounds released by solanaceous plants were trapped using a dynamic collection system, and analyzed by GC-MS. Solanum volatile profiles showed similarities, and were presenting quantitative and qualitative differences with the other tested solanaceous plants, providing some explanations in the observed behavioral discrimination. Further electrophysiological and behavioral assays are required to confirm the effect of specific chemicals on the choice of the oviposition site in T. absoluta. It can be concluded that Solanum species are the more suitable hosts for T. absoluta development. Other solanaceous plant species could be opportunistically colonized with little incidence but care should be taken in these results as genetic variability in insects and plants, as well as plant physiological state, might have an impact on the pest survivability. [less ▲]

Detailed reference viewed: 34 (2 ULg)
Peer Reviewed
See detailEfficiency of pheromone-based formulations against phytophagous pests
Fassotte, Bérénice ULg; Vandereycken, Axel ULg; Chevalier Mendes Lopes, Thomas ULg et al

Conference (2015, May 19)

Innovative integrated pest management methods are needed to overcome market withdrawal of synthetic pesticides. Therefore, the identification of environment-friendly bio-products carrying direct or ... [more ▼]

Innovative integrated pest management methods are needed to overcome market withdrawal of synthetic pesticides. Therefore, the identification of environment-friendly bio-products carrying direct or indirect biocide activity is one promising alternative option. Our researches focus on the identification of appropriate formulations releasing volatile organic compounds that are attractant for natural enemies of insect pests. However, the elaboration of slow-release devices that ensure stable and controlled release of active volatile compounds is quite challenging. Here, we developed a formulation based on E-β-farnesene and (-)-β-caryophyllene, these two semiochemicals having strong attractive potential on aphid natural enemies including lady beetles and hoverflies. Both compounds were encapsulated together in alginate gel beads. The blend efficiency was first evaluated through laboratory assays, and then in wheat and broad bean fields, by considering the abundance and diversity of aphids and their natural enemies. [less ▲]

Detailed reference viewed: 27 (3 ULg)
Full Text
See detailComputer simulations of spray retention by a 3D barley plant: effect of formulation surface tension
Massinon, Mathieu ULg; De Cock, Nicolas ULg; Ouled Taleb Salah, Sofiene ULg et al

in 67th International Symposium on Crop Protection (2015, May 19)

Detailed reference viewed: 29 (11 ULg)
Full Text
See detailDrop size distribution measurement of ISO nozzles by shadowgraphy method
De Cock, Nicolas ULg; Massinon, Mathieu ULg; Ouled Taleb Salah, Sofiene ULg et al

in Drop size distribution measurement of ISO nozzles by shadowgraphy method (2015, May 19)

Detailed reference viewed: 21 (2 ULg)
See detailAliphatic polyphosphates: a promising family of polymers for drug delivery
Vanslambrouck, Stéphanie ULg; Clément, Benoit; Riva, Raphaël ULg et al

Poster (2015, May 18)

Thanks to their biocompatibility and biodegradability, polyphosphates are appealing polymers for biomedical applications. In contrast to polyesters, polyphosphate properties and functionality are easily ... [more ▼]

Thanks to their biocompatibility and biodegradability, polyphosphates are appealing polymers for biomedical applications. In contrast to polyesters, polyphosphate properties and functionality are easily tuned via the chemical nature of the lateral chains. In this work, a series of amphiphilic PEO-block-polyphosphate copolymers were synthesized by organo-catalyzed ring-opening polymerization of cyclic phosphates. These polymers are directly dissolved in water in the absence of any organic solvent and they self-assemble to form nanoparticles Our work aims at changing the lateral chain of polyphosphates to investigate the influence of this structural modification on (i) the size of the nanoparticles, (ii) the critical aggregation concentration, (iii) the encapsulation of an hydrophobic drug in the core of the nanoparticles and, finally, (iv) the release of the drug. [less ▲]

Detailed reference viewed: 14 (2 ULg)
See detailPrerparation of graphene oxide-poly(methyl methacrylate) nanocompposites by a precipitation polymerization process and their dielectric and rheological characterization
Alkarmo, Walid ULg; Thomassin, Jean-Michel ULg; Macosko, Christopher et al

Poster (2015, May 18)

The graphene sheet, a flat monolayer composed of sp2-bonded carbon atoms packed into a two-dimensional honeycomb structure, has attracted a tremendous attention due to its extraordinary electrical ... [more ▼]

The graphene sheet, a flat monolayer composed of sp2-bonded carbon atoms packed into a two-dimensional honeycomb structure, has attracted a tremendous attention due to its extraordinary electrical, thermal, and mechanical properties. Graphene nanosheets–poly(methyl methacrylate) GN/PMMA nanocomposites were prepared via a precipitation polymerization process in a water/methanol mixture and thermal or chemical reduction of graphene oxide (GO). Scanning electron and transmission electron microscopies confirmed that the precipitate consists of polymer particles (<1μm) surrounded by the GO sheets. The GO sheets acts as a surfactant and adsorbs on the interface between polymerized PMMA particles and solvent mixture. Parallel dielectric and rheological characterization demonstrated that the thermal reduction is a quite fast process without significant degradation of the polymer. In addition, the main increase in electrical conductivity occurred during the first minutes of the thermal treatment but continued for about 30 min. The absence of dramatic change in the storage modulus confirmed that the increase in conductivity was not due to alteration of the particle dispersion. The addition of GO sheets had a dramatic influence on the glass transition (Tg) temperature of PMMA with an increase of 8 °C at only 0.2 wt %. This Tg increase has been attributed to the restricted mobility of PMMA chains which have been grafted onto the graphene surfaces during the in-situ polymerization. However, at GO content higher than 0.7 wt %, the glass transition decreases. This drop may be attributed to the increase in the number of stacked graphene layers. The obtained GN/PMMA composites not only have enhanced mechanical properties but also achieved electrical conductivity higher than 10 −2 S/m at 0.4 wt % of GO. The study should open up new opportunities in the design of GN-based polymer nanocomposites. [less ▲]

Detailed reference viewed: 71 (12 ULg)
Full Text
See detailAssessment of the species richness of highly eusocial bees according with habitat in Gabon
Fabre Anguilet, Edgard ULg; Bengone Ndong, Toussaint; Nguyen, Bach Kim ULg et al

Poster (2015, May 18)

Bees are among the most e ective pollinators. These insects include honeybee and stin- gless bee. In Africa, habitat loss is the main threat to these insects. This loss of habitat is largely due to ... [more ▼]

Bees are among the most e ective pollinators. These insects include honeybee and stin- gless bee. In Africa, habitat loss is the main threat to these insects. This loss of habitat is largely due to various human activities. An evaluation of the richness of social bees in three locaties in Gabon (Central Africa) was conducted from October 2013 to March 2014: Kougouleu who underwent deforestation and implantation of food crops, forest area Mas- sengalini in bu er zone of protected area of Lope and Lekokodiba in logging concession of Preccious Woods Gabon. For this, a collection was conducted using yellow traps lled with a mixture of water and honey and using a hand vacuum in 20 sites in each area. The number of species was compared to that estimated there are about thirty years. Eleven species of social bees (Apis mellifera adansonii and ten stingless bee species) were collected, of which 5 to Kougouleu, 8 to Massengalini and 11 to L ekokodiba. Honeybee has been collected in all localities. Forest localities are distinguished from Kougouleu by higher species diversity. This di erence is highly signi cant (Kruskal-Wallis 2 = 45.362, df = 2 and p-value<0.001). A decrease of approximately 50% of the number of stingless bee species in 30 years was found to Kougouleu, while the number of social bee species varies little in forest localities. Our study shows that the loss of forest habitat causes a decline in the species richness of social bees and stingless bees are more sensitive to this loss as the honeybee. [less ▲]

Detailed reference viewed: 22 (1 ULg)
See detailAging mechanisms in amorphous GeTe
Raty, Jean-Yves ULg; Zhang, Wei; Luckas, Jennifer et al

Conference (2015, May 18)

Aging phenomena are common to all amorphous structures, but of special importance in phase change materials (PCM) since it impedes the realization of multi-level memories. Different interpretations have ... [more ▼]

Aging phenomena are common to all amorphous structures, but of special importance in phase change materials (PCM) since it impedes the realization of multi-level memories. Different interpretations have been proposed, but we focus here on the structural relaxation of amorphous GeTe, chosen because it is the simplest system that is representative of the wider class of GST alloys, lying along the GeTe-Sb2Te3 composition line of the GeSbTe phase diagram. We investigate the structure of amorphous GeTe using Density Functional Theory based Molecular Dynamics, using either the standard Generalized Gradient Approximation, or more elaborate Van der Waals approximation. New insight is provided on the stability of homopolar GeGe bonds and tetrahedral Ge bonding, in relation with the resistance drift phenomenon, that is investigated experimentally using photothermal deflection spectroscopy experiments [less ▲]

Detailed reference viewed: 13 (1 ULg)
Full Text
See detailQuestion Intégrative - Médecine - Module Système Nerveux
Pasquet, Coralie ULg; Van de Poël, Jean-François ULg; Schaffer, Patrick ULg et al

Poster (2015, May 18)

Au cours du premier quadrimestre de l’année académique 2014 - 2015, une nouvelle activité a été proposée aux 270 étudiants inscrits en 3ième année du grade de Bachelier en Médecine à l’Université de Liège ... [more ▼]

Au cours du premier quadrimestre de l’année académique 2014 - 2015, une nouvelle activité a été proposée aux 270 étudiants inscrits en 3ième année du grade de Bachelier en Médecine à l’Université de Liège. Cette activité a été réalisée dans le cadre du « Module Système Nerveux ». [less ▲]

Detailed reference viewed: 27 (6 ULg)
Full Text
Peer Reviewed
See detailPrésentation de cas pratique - atelier n°2 « Outils et méthodes de formation : quels outils (EAD, MOOC, partage social, manuels...) et quelles méthodes (enseignement mixte, classe inversée, résolution de problèmes, travaux en groupe...) face à des groupes de tailles très variables ? Comment former avec peu de moyens (financiers, humains, matériels) ? »
Pasquet, Coralie ULg

Conference (2015, May 18)

Au cours du premier quadrimestre de l’année académique 2014 - 2015, une nouvelle activité a été proposée aux 280 étudiants inscrits en 3ième année du grade de Bachelier en Médecine à ... [more ▼]

Au cours du premier quadrimestre de l’année académique 2014 - 2015, une nouvelle activité a été proposée aux 280 étudiants inscrits en 3ième année du grade de Bachelier en Médecine à l’Université de Liège, ce dans le cadre du « Module Système Nerveux ». La réalisation progressive de cette activité s'est effectuée exclusivement en ligne. [less ▲]

Detailed reference viewed: 55 (5 ULg)
See detailA tool for the precision synthesis of poly(ionic liquid)s in water
Cordella, Daniela ULg; Kermagoret, Anthony; Debuigne, Antoine ULg et al

Conference (2015, May 18)

In recent years, poly(ionic liquid)s (PIL)s were found to take an enabling role in important fields of polymer chemistry and material science. PILs combine the unique properties of ionic liquids with the ... [more ▼]

In recent years, poly(ionic liquid)s (PIL)s were found to take an enabling role in important fields of polymer chemistry and material science. PILs combine the unique properties of ionic liquids with the flexibility and properties of macromolecular architectures giving rise to a new family of functional polymers that opens new area of applications such as polymer electrolytes in electrochemical devices, powerful dispersants and stabilizers, absorbing membranes, precursors for carbon materials, porous polymers, etc. In this communication, we will report on the implementation of organometallic-mediated radical polymerization (OMRP) technique for the precision synthesis of unprecedented PILs (co)polymers. We will discuss how an organocobalt complex can efficiently control the growth of vinyl imidazolium chains and lead to PILs with predicted molar masses and low polydispersities under mild experimental conditions, which provide low temperatures (compared to the conventional radical polymerization techniques) and also the use of water as green polymerization medium. The huge potential of this system will be also highlighted by describing the one-pot synthesis of vinyl imidazolium-based block copolymers in heterogeneous conditions. This OMRP is unique for providing well-defined vinyl imidazolium based-copolymers opening for advanced PILs applications. [less ▲]

Detailed reference viewed: 28 (1 ULg)
See detailNon-isocyanate polyurethane: from the monomer synthesis to foamed materials
Gennen, Sandro ULg; Alves, Margot ULg; Tassaing, Thierry et al

Poster (2015, May 18)

Polyurethane (PU) is one of the most important polymers in our everyday life with numerous applications such as thermosets, thermoplastics, elastomers, adhesives, sealants, coatings, rigid and flexible ... [more ▼]

Polyurethane (PU) is one of the most important polymers in our everyday life with numerous applications such as thermosets, thermoplastics, elastomers, adhesives, sealants, coatings, rigid and flexible foams... Classically, PUs are produced by a step-growth polymerization between diols and diisocyanates. However, isocyanates are harmful upon prolonged exposure to vapours which can lead to health issues such as asthma and skin irritation. In addition, isocyanates are produced from even more toxic and explosive phosgene. Due to these problems in combination with increasing regulatory scrutiny, there is today a need to develop isocyanate- and phosgene free- PU synthesis, also called non-isocyanate polyurethane or NIPUs. One of the most promising alternatives to the conventional synthesis of PU relies on the step-growth polymerization between bicyclic carbonate monomers and diamines, but until now, obtaining high molar mass NIPUs in a short time still remains a challenge. This study will be focused on three objectives: 1) The synthesis of CO2-sourced biscyclic carbonates by CO2/epoxide coupling using new highly efficient bicomponent organocatalysts allowing the fast conversion of epoxides into the corresponding cyclic carbonates under mild and solvent-free conditions. 2) The synthesis of high molar mass NIPUs from CO2-sourced monomers and diamines thanks to the use of efficient organocatalysts. A series of organic compounds interacting with cyclic carbonates by hydrogen bonding were first identified and their catalytic activity was highlighted by a model reaction between ethylene carbonate and a primary amine before extrapolation to NIPU synthesis. 3) The scCO2-assisted foaming of CO2-sourced NIPUs with production of potential carbon zero-emission materials with low thermal conductivity [less ▲]

Detailed reference viewed: 49 (1 ULg)
Full Text
See detailDémocratie et populisme: quelle réalité pour quelle légitimité?
Biard, Benjamin; Debras, François ULg

Conference (2015, May 18)

Detailed reference viewed: 22 (12 ULg)
See detailOrganometallic-mediated radical synthesis of well-defined ethylene-vinyl acetate statistical and block copolymers
Demarteau, Jérémy ULg; Kermagoret, Anthony; Jérôme, Christine ULg et al

Poster (2015, May 18)

The copolymerization of ethylene (E) and vinyl acetate (VAc) is of high interest for polymer industry. Nevertheless, the control of the macromolecular parameters of ethylene-vinyl acetate copolymers (EVAs ... [more ▼]

The copolymerization of ethylene (E) and vinyl acetate (VAc) is of high interest for polymer industry. Nevertheless, the control of the macromolecular parameters of ethylene-vinyl acetate copolymers (EVAs) is difficult to achieve. Herein, we report the controlled radical copolymerization of these monomers by organometallic-mediated radical polymerization (OMRP) using Co(acac)2 as controlling agent. The ethylene pressure is varied from 10 to 100 bar and we discuss the effect of this parameter on kinetics, level of control and copolymer composition. EVAs are synthetized accordingly with low dispersities and ethylene content reaches up to 57 mol%. The precision design of EVA-containing block copolymers, i.e. PVAc-block-EVA, is also addressed. [less ▲]

Detailed reference viewed: 19 (4 ULg)
See detailNew efficient bicomponent organocatalysts for the chemical fixation of CO2 onto epoxides: a theoretical study
Alves, Margot ULg; Méreau, Raphaël; Grignard, Bruno ULg et al

Poster (2015, May 18)

Regarding the economic and environmental issues, valorising CO2 as a C1 feedstock for producing useful building blocks is seducing as it is a free and abundant waste resulting from the human activity ... [more ▼]

Regarding the economic and environmental issues, valorising CO2 as a C1 feedstock for producing useful building blocks is seducing as it is a free and abundant waste resulting from the human activity. Cyclic carbonates are useful compounds that found application as green solvents, electrolytes for lithium battery or monomers for polycarbonates or polyurethanes synthesis. These cyclocarbonates can be synthesized with a total atom economy by chemical fixation of CO2 onto epoxides using organometallic complexes or organocatalysts. To date, although this area of research has been the subject of many studies, the identification and development of (organo)catalysts highly efficient under mild experimental conditions still remains challenging. In this context, we developed a new organocatalytic platform based on the use of ammonium salts in combination with single or double hydrogen bond donor activators derived from fluorinated alcohols that showed unexpected booster effect. In this contribution, the ammonium/fluoroalcohol promoted CO2/propylene oxide coupling was investigated through detailed kinetic studies by IR spectroscopy under pressure and results were compared to the most efficient organocatalysts based on ammonium salts and (multi)phenolic derivatives that were reported in the literature. In order to finely understand the reaction mechanism, this study was completed by molecular modeling. DFT calculations showed that the addition of H-bond donors (HBD) with hexafluoroisopropanol functionalities modified the mechanism of the ammonium promoted coupling of CO2 with epoxides. HBDs dramatically decreased the epoxide ring-opening step barrier which highlights the key role of the fluorinated activators in stabilizing the intermediates and transitions states by inter- and intra-molecular hydrogen bonds. [less ▲]

Detailed reference viewed: 38 (1 ULg)
Full Text
See detailRelever le défi des outils « discovery » : les formations orientées vers l’usager
Decoster, Sara ULg

Conference (2015, May 18)

Orientés vers l’usager, reprenant les habitudes de la génération « google », les outils « discovery » remettent en question le postulat que c’est à l’usager d’étudier la recherche documentaire. Les ... [more ▼]

Orientés vers l’usager, reprenant les habitudes de la génération « google », les outils « discovery » remettent en question le postulat que c’est à l’usager d’étudier la recherche documentaire. Les bibliothèques sont invitées à aller vers l’utilisateur et à se réinventer autour de la notion de « service ». Dans un monde informationnel où les enjeux sont de plus en plus complexes, le service à l’usager implique plus que jamais que la bibliothèque joue le rôle d’intermédiaire entre l’information et l’usager. Si l’usager doit rester maître de l’information, la formation aux compétences informationnelles reste à l’ordre du jour. Donnant cours à l’aide d’un outil « discovery », j’ai conclu qu’il est nécessaire de sortir du cadre très technique d’une recherche documentaire centrée sur la typologie documentaire et les équations de recherche. Ces éléments n’ont pas perdu leur pertinence, mais doivent être intégrés dans une structure basée sur les tâches et compétences de l’utilisateur, à savoir, la compréhension des possibilités et des limites des divers outils, l’interprétation des références et les phases de sélection, obtention et évaluation de l’information. Le but final sera toujours de permettre à l’usager de devenir acteur de l’information et de trouver sa propre position dans le paysage documentaire. Si les outils « discovery » nous amènent à faire le passage de la technicité à une approche par compétences, ils nous permettent de concevoir des formations véritablement orientées utilisateur. Tel est le défi que je voudrais relever en restructurant mes activités d’enseignement. [less ▲]

Detailed reference viewed: 306 (11 ULg)
See detailIntercalation of cationic aliphatic polyphosphates between montmorillonite nanosheets towards flame-retardant polymer materials
Carion, Stéphan ULg; Lecomte, Philippe ULg; Thomassin, Jean-Michel ULg et al

Poster (2015, May 18)

Among the strategies used to impart flame-retardant properties to polymer materials, the most effective ones include the addition of phosphorous compounds such as organic polyphosphates and the dispersion ... [more ▼]

Among the strategies used to impart flame-retardant properties to polymer materials, the most effective ones include the addition of phosphorous compounds such as organic polyphosphates and the dispersion of layered silicates (nanoclays). The aim of this work is to combine both approaches by the dispersion of nanoclays, organomodified by cationic aliphatic polyphosphates, into a polymer matrix. In this work, the synthesis of an aliphatic polyphosphate end-capped by an imidazolium cation followed by its intercalation between montmorillonite nanoclays sheets is reported. In a first step, the polyphosphate was synthesized by ring-opening polymerization of the corresponding cyclic phosphate using 1-(11-hydroxy-undecyl)-3-methylimidazolium bromide as initiator. This polymerization was catalyzed by DBU and a thiourea derivative. This polymer was characterized by different techniques (31P and 1H NMR, SEC, TGA, DSC). Finally, the cationic end-functionalized polymer was exchanged with sodium cations present in montmorillonite. The intercalation of the polyphosphate between the clay nanosheets was proved by X-Ray Diffraction (XRD) and thermogravimetric analysis (TGA). This last technique was also used to determine the influence of the intercalation on the thermal stability of the polyphosphate.polyphosphates, into a polymer matrix. In this work, the synthesis of an aliphatic polyphosphate end-capped by an imidazolium cation followed by its intercalation between montmorillonite nanoclays sheets is reported. In a first step, the polyphosphate was synthesized by ring-opening polymerization of the corresponding cyclic phosphate using 1-(11-hydroxy-undecyl)-3-methylimidazolium bromide as initiator. This polymerization was catalyzed by DBU and a thiourea derivative. This polymer was characterized by different techniques (31P and 1H NMR, SEC, TGA, DSC). Finally, the cationic end-functionalized polymer was exchanged with sodium cations present in montmorillonite. The intercalation of the polyphosphate between the clay nanosheets was proved by X-Ray Diffraction (XRD) and thermogravimetric analysis (TGA). This last technique was also used to determine the influence of the intercalation on the thermal stability of the polyphosphate. [less ▲]

Detailed reference viewed: 30 (4 ULg)
See detailDesign of new multifunctional nanocarriers for protein delivery
Parilti, Rahmet ULg; Jérôme, Christine ULg; Howdle, Steven M. et al

Conference (2015, May 18)

Polymeric nanoparticles have been extensively investigated for their biomedical applications especially as drug carriers. However, efficient encapsulation and delivery of therapeutic proteins in targeted ... [more ▼]

Polymeric nanoparticles have been extensively investigated for their biomedical applications especially as drug carriers. However, efficient encapsulation and delivery of therapeutic proteins in targeted manner still present challenges. This project aims to develop a novel one-pot strategy to obtain nanoparticles able to carry proteins in their core, as well as bearing targeting and/or imaging agents on their surface. In addition to this objective, polymerizations are carried out in supercritical carbon dioxide (scCO2), which confers environmentally benign features to the process. Dispersion polymerizations of hydrophilic monomer 2-hydroxyethyl methacrylate (HEMA) in are carried out in scCO2 in the presence of an initiator, cross-linker and CO2-philic photoclevable stabilizer. Upon exposure to UV light, the o-nitrobenzyl junctions present at the surface of the particles are cleaved, thus providing water dispersible hydrogels. Spherical monodisperse nanoparticles were successfully synthesized in scCO2 with two different conditions. Milder reaction conditions were achieved by using 2,2'-Azobis(4-methoxy-2,4-dimethyl valeronitrile (V70) as an initiator which opens up the platform for one-pot protein encapsulation in scCO2. [less ▲]

Detailed reference viewed: 19 (2 ULg)
Full Text
See detailClassical analogy for the deflection of flux avalanches by a metallic layer
Silhanek, Alejandro ULg

Conference (2015, May 17)

Motivated by the experimental observation of the exclusion of magnetic flux avalanches in a superconducting sample partially covered by a conducting capping layer, we have investigated the simpli fied ... [more ▼]

Motivated by the experimental observation of the exclusion of magnetic flux avalanches in a superconducting sample partially covered by a conducting capping layer, we have investigated the simpli fied case of the interaction of a magnetic charge (monopole and dipole) with a semi-in finite conducting plane. We have found that early theoretical descriptions for the damping enhancement due to the metallic sheet needed a correction at large vortex velocities where a decrease of the damping coe fficient is expected. We also demonstrate that vortex trajectories are strongly modi fied when penetrating into the area covered by the metallic sheet and may even be fully diverted from that area thus providing a qualitative explanation for the bending of the trajectories of flux avalanches. Our fi ndings may be extended to study the damping of Larkin-Ovchinnikov vortex instabilities and phase-slip lines in current driven systems. [less ▲]

Detailed reference viewed: 17 (1 ULg)
See detailVaricella-Zoster Virus (VZV) assemblons interplay with PML bodies
Lebrun, Marielle ULg; Thiry, Marc ULg; Sadzot, Catherine ULg

Poster (2015, May 15)

Using a virus expressing the small capsid protein fused to an eGFP tag (eGFP-ORF23 VZV), we recently identified, in the nuclei of infected cells, the presence of dynamic capsid aggegrates. Because we ... [more ▼]

Using a virus expressing the small capsid protein fused to an eGFP tag (eGFP-ORF23 VZV), we recently identified, in the nuclei of infected cells, the presence of dynamic capsid aggegrates. Because we believe that these structures might represent sites of preferential caspid assembly and by analogy with HSV-1, we referred to them as “VZV assemblons”. Structures resembling these assemblons and identified as capsids entrapped in some “PML-cages” were recently described in the nuclei of wild-type VZV infected cells (Reichelt et al., 2011). We then wonder if there was a link between these independent observations. When we infected MeWo cells in which the expression of each PML subunit is downregulated by shRNA, VZV assemblons still formed. Immunostaining of MeWo cells infected by eGFP-ORF23 VZV with an antibody against the PML protein showed that VZV assemblons only partially colocalize with PML bodies. However, overexpression of PML-I-eGFP in HEK293 cells followed by infection with a tagRFP-T-ORF23 VZV, where the ORF23 protein is fused to a red tag, showed a complete colocalization is complete. The same result was obtained with all tested PML isoforms. This suggests that the partial colocalization in normal cells could be due to the expression level of PML proteins. Altogether, these results suggest that rather than a progressive accumulation of newly formed capsids within PML cages, it is likely that PML protein is recruited to the sites where VZV assemblons develop. It correlates with the fact that the number of PML bodies decreases with the infection. Obviously, even if this phenomenon might impede the egress of a substantial amount of capsids and, in this regard, limit the infection progression, all the tested cell lines are permissive to VZV. It would then be interesting to investigate the relationship between VZV assemblons and PML bodies in latent or non permissive VZV infection models. [less ▲]

Detailed reference viewed: 8 (0 ULg)
See detailWhy are flux avalanches deflected by a metallic layer?
Brisbois, Jérémy ULg

Conference (2015, May 15)

Sudden avalanches of magnetic flux bursting into a superconducting sample are deflected from their trajectories when they encounter a conductive layer deposited on top of the superconductor. Remarkably ... [more ▼]

Sudden avalanches of magnetic flux bursting into a superconducting sample are deflected from their trajectories when they encounter a conductive layer deposited on top of the superconductor. Remarkably, in some cases the flux is totally excluded from the area covered by the conductive layer. Even if this phenomenon has been known for a few years, there is currently no theoretical model describing it. Moreover, the question whether the deflection would also be observed for a single vortex entering the region covered by a metallic layer is still unanswered. In this work we use the magneto-optical imaging (MOI) technique, based on the Faraday effect, to show that a conductive layer (Cu) can repel flux avalanches triggered in an underlying superconducting film (Nb) (see figure). We present a simple classical model that accounts for the deflection of a single vortex and considers a magnetic monopole approaching a semi-infinite conductive plane. This model suggests the important role played in the avalanche deflection by electromagnetic braking, arising from the eddy currents induced by the moving vortex in the metal. Moreover, we have found a decrease of the vortex damping coefficient due to the metallic sheet at large vortex velocities, correcting early theoretical descriptions where a linear behaviour was proposed. [less ▲]

Detailed reference viewed: 6 (2 ULg)
Peer Reviewed
See detailWhat makes the invasive Harmonia axyridis so successful? Six years of research in Gembloux provide additional answers
Fassotte, Bérénice ULg; Durieux, Delphine ULg; Vandereycken, Axel ULg et al

Conference (2015, May 14)

Following the introduction of the invasive species Harmonia axyridis (Pallas) in Europe, many research works were conducted on its ecological, economic and social impacts. Recently, our team has been ... [more ▼]

Following the introduction of the invasive species Harmonia axyridis (Pallas) in Europe, many research works were conducted on its ecological, economic and social impacts. Recently, our team has been involved in the characterization of the behavioral traits making this lady beetle species so successful. The main conclusions of two PhD works will be shortly presented: (1) Through a six-year inventory performed in Belgian agroecosystems, we have demonstrated that H. axyridis has become well established and was among the most abundant aphidophagous predatory species, causing a severe depression of biodiversity, even if communities of aphid predators are still quite diversified. (2) The social issues associated with the establishment of overwintering aggregations in human constructions were also carefully investigated. We have demonstrated the importance of social interactions on the establishment and cohesion of the aggregates. Finally, we have demonstrated that the deposition of a set of saturated and non-saturated hydrocarbons on the surfaces where the lady beetles were settling on, allowed their conspecifics to follow their markings and join the group. [less ▲]

Detailed reference viewed: 27 (5 ULg)
See detailChristianisme et paideia dans l'Égypte byzatine : l'apport des papyrus scolaires grecs à contenu composite profane et chrétien (fin du IIIe-début du VIIIe s.)
Carlig, Nathan ULg

Conference (2015, May 14)

Documentée par des milliers de papyrus, restes de livres ou de documents, dont les plus anciens remontent à la fin du IIe siècle de notre ère, la christianisation de l’Égypte a profondément modifié le ... [more ▼]

Documentée par des milliers de papyrus, restes de livres ou de documents, dont les plus anciens remontent à la fin du IIe siècle de notre ère, la christianisation de l’Égypte a profondément modifié le rapport des populations à la paideia hellénique, sans pour autant se substituer à elle. L’examen du matériau, de la forme, de la mise en page, du contenu, ainsi que de la provenance des papyrus scolaires grecs à contenu composite profane et chrétien (fin IIIe – 1e moitié VIIIe s.), permettra d'illustrer cette problématique en relevant les continuités et les ruptures dans les stratégies d'enseignement par rapport à la paideia de tradition hellénique. [less ▲]

Detailed reference viewed: 12 (1 ULg)
Full Text
See detailInteraction of HTLV-1 Tax with minichromosome maintenance proteins modulates viral transcription
Barez, Pierre-Yves ULg; Carpentier, Alexandre ULg; Boxus, Mathieu et al

Poster (2015, May 13)

First human retrovirus discovered, HTLV-1 infects approximately twenty million individuals worldwide. HTLV-1 is the causative agent of different diseases that include adult T-cell leukemia (ATL) and a ... [more ▼]

First human retrovirus discovered, HTLV-1 infects approximately twenty million individuals worldwide. HTLV-1 is the causative agent of different diseases that include adult T-cell leukemia (ATL) and a neurodegenerative disorder called HAM/TSP (Human associated myelopathy/ Tropical spastic paraparesis). We are interested in the mechanisms of transformation by the viral Tax oncoprotein. We previously showed that Tax interacts with the minichromosome maintenance MCM2-7 helicase and affects host cell replication (Boxus et al, 2012 Blood 119:151). In this project, we focused on the role of the MCM2-7 complex in transcription. We first show by chromatin immunoprecipitation that the MCM2-7 is recruited onto the 5'-LTR promoter. The 5’-LTR does however not act as a DNA replication origin. In contrast, MCM2-7 activates viral transcription as revealed by luciferase reporter assays. Interaction between Tax and MCM2-7 also affect expression of cellular genes. Together, our data thus demonstrate that the viral promoter is not a replication origin and that interaction between Tax and MCM2-7 is involved in the viral transcription. [less ▲]

Detailed reference viewed: 22 (8 ULg)
Full Text
See detailAuroral emissions at Jupiter and Saturn, at the crossroads of Astrophysics Geophysics and Plasma Physics
Grodent, Denis ULg

Conference (2015, May 13)

Auroral physics is at the intersection of more general fields of physics such as Astrophysics, Geophysics and Plasma Physics. In particular, the giant planets Jupiter and Saturn may be seen as slow ... [more ▼]

Auroral physics is at the intersection of more general fields of physics such as Astrophysics, Geophysics and Plasma Physics. In particular, the giant planets Jupiter and Saturn may be seen as slow rotating pulsars. For these two planets, there is a direct link between this pulsar-like behaviour and the auroral processes that are taking place in their atmosphere. We will take the example of Jupiter to illustrate haw the aurora is generated in the magnetosphere as a result of the volcanic activity of the moon Io. [less ▲]

Detailed reference viewed: 12 (0 ULg)
Full Text
See detailMagneto-optical trapping of iron atoms
Crauwels, Justine ULg; Huet, Nicolas ULg; Krins, Stéphanie ULg et al

Poster (2015, May 13)

Detailed reference viewed: 19 (4 ULg)
See detailAn encapsulation-dehydration method for the long-term storage of cyanobacterial strains in the BCCM/ULC collection.
Crahay, Charlotte ULg; Mari, Maude; Wilmotte, Annick ULg

Poster (2015, May 13)

Long-term genetic and functional stability is a fundamental requirement for the maintenance of microorganisms. Cryopreservation is the preferred method for the long-term storage of many micro-organisms ... [more ▼]

Long-term genetic and functional stability is a fundamental requirement for the maintenance of microorganisms. Cryopreservation is the preferred method for the long-term storage of many micro-organisms, including cyanobacteria. The BCCM/ULC collection currently holds over 200 cyanobacterial strains as living cultures, but only 62 are maintained in a cryo-preserved state. The main limiting factors are the low levels of survival of some strains, as well as the long periods required to recover from cryopreservation, and thus the inability to rapidly deliver strains to clients.. The BRAIN-be project PRESPHOTO (preservation of photosynthetic micro-algae in the BCCM collections) (www.presphoto.ulg.ac.be) aims to improve the preservation of cyanobacterial and diatoms in the BCCM/ULC and BCCM/DCG collections, respec-tively. The encapsulation-dehydration is often considered as a promising alternative to the traditional cryopreservation method for recalcitrant microalgal strains. In this technique, cyanobacterial cultures are entrapped in calcium-alginate beads, osmotically dehydrated (traditionally with sucrose solutions), then evaporatively desiccated in a sterile air flow, or over silica gel and subsequently cryopreserved. In this study, the encapsulation-dehydration method was evaluated as potential long-term preservation technique of cyanobacterial strains. The effects of several factors on the viability of 4 strains have been investigated to determine which are the most important for the successful cryopreservation. In particular, several cryoprotectants (i.e. sucrose, PEG or mannitol), methods of beads dehydration (i.e. under a laminar flow or with silica gel) were tested. We have also compared storage at -70°C and in liquid nitrogen (-196oC). A pre-cultivation step in KCl was also tested for its ability to enhance desiccation tolerance. In addition, the use of alginate dissolution buffer following thawing was also considered. In the final phase of the project, the selected cryopreservation protocols will be tested on a large set of strains. In addition, an independent validation of the protocols will be also performed by both partners of the project (BCCM/DCG and the Culture Collection of Algae and Protozoa). [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailTransport of Bose-Einstein Condensates through Aharonov-Bohm rings
Chrétien, Renaud ULg; Dujardin, Julien ULg; Petitjean, Cyril ULg et al

Poster (2015, May 13)

We study the one-dimensional (1D) transport properties of an ultracold gas of Bose-Einstein condensed atoms through Aharonov-Bohm (AB) rings. Our system consists of a Bose-Einstein condensate (BEC) that ... [more ▼]

We study the one-dimensional (1D) transport properties of an ultracold gas of Bose-Einstein condensed atoms through Aharonov-Bohm (AB) rings. Our system consists of a Bose-Einstein condensate (BEC) that is outcoupled from a magnetic trap into a 1D waveguide which is made of two semi-infinite leads that join a ring geometry exposed to a magnetic flux φ. We specifically investigate the effects of a small atom-atom contact interaction strength on the AB oscillations. The main numerical tools that we use for this purpose are a mean-field Gross-Pitaevskii (GP) description and the truncated Wigner (tW) method. The latter allows for the description of incoherent transport and corresponds to a classical sampling of the evolution of the quantum bosonic many-body state through effective GP trajectories. We find that resonant transmission peaks move with an increasing interaction strength and can be suppressed for sufficiently strong interaction. We also observe that the coherent transmission blockade due to destructive interference at the AB flux φ = π is very robust with respect to the interaction strength. [less ▲]

Detailed reference viewed: 62 (15 ULg)
Peer Reviewed
See detailGrowth factor-induced angiogenesis requires uPAR on endothelial cells
Paques, Cécile ULg

Poster (2015, May 13)

Detailed reference viewed: 7 (0 ULg)
Full Text
See detailInvestigation on a hydrogen maser cavity in the TE111 mode : first results
Van Der Beken, Emeline ULg; Léonard, Daniel; Counet, Arnaud et al

Poster (2015, May 13)

Results of our preliminary investigation on a hydrogen maser cavity in the unusual TE111 mode are presented. Hydrogen masers use the transition at 1420.405MHz between the two hyperfine levels F = 0 and F ... [more ▼]

Results of our preliminary investigation on a hydrogen maser cavity in the unusual TE111 mode are presented. Hydrogen masers use the transition at 1420.405MHz between the two hyperfine levels F = 0 and F = 1 of the 1s1/2 ground state of the hydrogen atom. In contrast to standard hydrogen maser that exploits the TE011 mode, the TE111 mode allows one to design hydrogen masers with significant reduced dimensions, which represents a huge benefit for space applications and in particular for the global positioning system. In view of a future development of a hydrogen maser in the TE111 mode we performed a thorough analysis of the maser physics for this mode. Different simulations carried out are compared with first measurement results obtained for such a cavity. [less ▲]

Detailed reference viewed: 24 (2 ULg)
Full Text
Peer Reviewed
See detailIs the natural shape of ions in the gas phase spherical ? The allegory of the cave (Plato) applied in mass spectrometry
Far, Johann ULg; Haler, Jean ULg; Kune, Christopher ULg et al

Conference (2015, May 13)

The transfer of ions from solution to gas phase is a critical step to produce « native species ». Coming from a highly solvating medium, ionic species will tend to find new equilibrium conformations in ... [more ▼]

The transfer of ions from solution to gas phase is a critical step to produce « native species ». Coming from a highly solvating medium, ionic species will tend to find new equilibrium conformations in the gas phase. The pathway to reach the thermodynamically stable conformation(s) involves crossing potential barriers according to the type of interactions involved. When these barriers are too high compared to the internal energy of the ions, it may result in a “partial memory” (as structural preservation) of the conformation in solution. In order to evaluate the effect of the solvent evaporation and of the various collision processes encountered by the ions in the mass spectrometer we based our strategy on the determination of deviations from a spherical shape, supposed to be the natural state of ions in the gas phase. [less ▲]

Detailed reference viewed: 36 (16 ULg)
Full Text
See detailOn the nature of cosmological time
Hauret, Clémentine ULg

Conference (2015, May 13)

Detailed reference viewed: 8 (4 ULg)
See detailJupiter's equatorward auroral features
Dumont, Maïté ULg; Grodent, Denis ULg; Radioti, Aikaterini ULg et al

Conference (2015, May 13)

Detailed reference viewed: 19 (3 ULg)
Full Text
See detailTowards the identification of cis-elements responsible for the high expression of HMA4, an essential gene for zinc hyperaccumulation in Arabidopsis halleri.
Spielmann, Julien ULg; Nouet, Cécile ULg; Scheepers, Maxime ULg et al

Poster (2015, May 13)

A. halleri is a Zn and Cd hypertolerant and hyperaccumulator plant which stores metals in shoot vacuoles. One key step for hyperaccumulation is a highly efficient root-to-shoot translocation of metals ... [more ▼]

A. halleri is a Zn and Cd hypertolerant and hyperaccumulator plant which stores metals in shoot vacuoles. One key step for hyperaccumulation is a highly efficient root-to-shoot translocation of metals. The Zn/Cd plasmamembrane pump HMA4 (heavy metal ATPase 4) plays a central role in this process and is involved in xylem loading/unloading. Moreover, HMA4 is overexpressed in A. halleri compare to its non-tolerant and non-hyperaccumulator sister, Arabidopsis thaliana. The HMA4 overexpression is determined by a combination of gene triplication and cis-regulatory changes increasing transcription levels of each three HMA4 copies. In this study, we are focusing on the two most active HMA4 promoters and we aim to identify the cis-elements underlying high expression of HMA4 in A. halleri using promoter-reporter constructs. Through deletion analysis, two important regions for a high expression have been identified. Ongoing analysis of more detailed deletions will be presented. [less ▲]

Detailed reference viewed: 22 (5 ULg)
See detailFirst experimental realization of an Iron Magneto-Optical Trap
Bastin, Thierry ULg; Crauwels, Justine ULg; Huet, Nicolas ULg et al

Conference (2015, May 13)

Detailed reference viewed: 23 (2 ULg)
Full Text
See detailDesign and synthesis of PET-probes targeting AMPA subtype receptors
Deverdenne, François ULg; Claes, Giselle ULg; Goffin, Eric ULg et al

Poster (2015, May 13)

The AMPA subtype of glutamatergic receptors is the main actor in the fast excitatory neurotransmission in the mammalian central nervous system. These receptors are involved in the expression and the ... [more ▼]

The AMPA subtype of glutamatergic receptors is the main actor in the fast excitatory neurotransmission in the mammalian central nervous system. These receptors are involved in the expression and the maintenance of the long-term potentiation, a phenomenon closely linked to cognitive and memorization processes. Based on experimental data, it also appears that glutamatergic systems are involved in several pathological diseases. For instance, a lack of glutamatergic neurotransmission is observed in cognitive disorders or schizophrenia and an excessive activity is observed in Parkinson or Huntington diseases. The in vivo study of glutamate receptors mapping and its evolution appears to be an essential step for a better understanding of its implications. However, according to the literature, design of such a probe remains difficult due to the lack of specificity of the probes. Taking into account the potential in vitro and in vivo activity and specificity of benzothiadizine dioxides (BTDs) acting as AMPA positive allosteric modulators, we are investing the development of new compounds of this class radiolabeled with a fluorine-18 atom. Hence, we are currently developing new series of BTDs characterized by the presence of a fluorine atom and a 7-phenoxy-substituent that are expected to be more active and more specific. Finally, pharmacological tests to evaluate the best candidates for the radiochemical synthesis and in vivo evaluations are currently in progress. [less ▲]

Detailed reference viewed: 11 (6 ULg)
Full Text
See detailAnticoherence of multiqubit symmetric states
Baguette, Dorian ULg; Bastin, Thierry ULg; Martin, John ULg

Conference (2015, May 13)

Detailed reference viewed: 10 (0 ULg)
Full Text
See detailCheckpoints modulation by the human T-lymphotropic virus type 1 (HTLV-1) Tax protein : towards new therapeutic approaches
Carpentier, Alexandre ULg; Barez, Pierre-Yves ULg; Boxus, Mathieu et al

Poster (2015, May 13)

HTLV-1 infects approximately 15 million people worldwide and causes several diseases. This virus is responsible for the adult T-cell leukemia (ATL) and for a chronic neuropathology (TSP/HAM). There is ... [more ▼]

HTLV-1 infects approximately 15 million people worldwide and causes several diseases. This virus is responsible for the adult T-cell leukemia (ATL) and for a chronic neuropathology (TSP/HAM). There is currently no satisfactory treatment for these diseases. Among the proteins encoded by HTLV-1, Tax appears to play an important role in the mechanisms leading to pathogenicity. We are interested in the mechanisms of cell transformation by the Tax viral oncoprotein. In particular, we aim at understanding the interplay between Tax and the DNA damage response (DDR). We show that transient expression of Tax results in DNA damage, cell cycle arrest and activation of the DDR. In fibroblasts, cell cycle arrest occurs at the G1 and G2 phases depending on the p53 background. In contrast, HTLV-1 infected lymphocytes proliferate continuously and appear to be adapted to the checkpoints. This mechanism of checkpoint adaptation thus allows ongoing proliferation despite the presence of genomic lesions. Quantification of the rates of NHEJ and homologous recombination indicates that HTLV-1 infected cells require very efficient DNA repair for survival. Therefore, we propose a novel therapeutic approach based on the principle of synthetic lethality using inhibitors of DNA repair. [less ▲]

Detailed reference viewed: 7 (3 ULg)
Full Text
See detailMultiscale model of the human cardiovascular system: healthy and pathological behaviours
Kosta, Sarah ULg; Negroni, Jorge; Lascano, Elena et al

Poster (2015, May 13)

Detailed reference viewed: 23 (4 ULg)
Full Text
See detailChaotic Bohmian trajectories for the hydrogen atom
Cesa, Alexandre ULg; Struyve, Ward ULg; Martin, John ULg

Poster (2015, May 13)

In Bohmian mechanics, a single-particle quantum system is described in part by its wave function and in part by the actual position of the particle. The trajectory of the latter can be computed using the ... [more ▼]

In Bohmian mechanics, a single-particle quantum system is described in part by its wave function and in part by the actual position of the particle. The trajectory of the latter can be computed using the guiding equation. This equation states that the velocity of the particle is proportional to the usual probability current associated with its wave function. In this work, we study the quantum trajectory of a single particle in a Coulomb potential whose eigenstates are the well known eigenstates of the hydrogen atom. More precisely, we focus on the relation between chaotic Bohmian trajectories and the motion of wave function nodes. At wave function nodes i.e., where the wave function vanishes, the velocity is not defined which generically induces vorticity. In order to probe chaos, we compute Poincaré map and we numerically evaluate Lyapounov exponents, which characterize the divergence of close trajectories as time increases. For the 2d Coulomb potential, although the superposition of two eigenstates with different energies can lead to an arbitrary high number of moving nodes of the wave function, the Bohmian trajectories display no trace of chaos. This absence of chaotic behaviour originates from the existence of a constant of motion. Therefore, the motion and the number of nodes do not constitute a sufficient condition for the emergence of chaos in Bohmian mechanics. For superpositions of more than two eigenstates, there is no constant of motion, there are moving nodes and we find that the Bohmian trajectories are chaotic. [less ▲]

Detailed reference viewed: 22 (4 ULg)
Peer Reviewed
See detailFirst evidence of a volatile sex pheromone in Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae)
Fassotte, Bérénice ULg; Fischer, Christophe ULg; Durieux, Delphine ULg et al

Conference (2015, May 13)

To date, volatile sex pheromones have not been identified in the Coccinellidae family; yet, various studies have suggested that such semiochemicals exist. Here, we collected volatile chemicals released by ... [more ▼]

To date, volatile sex pheromones have not been identified in the Coccinellidae family; yet, various studies have suggested that such semiochemicals exist. Here, we collected volatile chemicals released by virgin females of the multicolored Asian lady beetle, Harmonia axyridis (Pallas), which were either allowed or not allowed to feed on aphids. Virgin females in the presence of aphids, exhibited “calling behavior”, which is commonly associated with the emission of a sex pheromone in several Coleoptera species. These calling females were found to release a blend of volatile compounds that is involved in the remote attraction (i.e., from a distance) of males. Gas Chromatography Mass Spectrometry (GC-MS) analyses revealed that (–)-β-caryophyllene was the major constituent of the volatile blend (ranging from 80 to 86%), with four other chemical components also being present; β-elemene, methyl-eugenol, α-humulene, and α-bulnesene. In a second set of experiments, the emission of the five constituents identified from the blend was quantified daily over a 9-day period after exposure to aphids. We found that the quantity of all five chemicals significantly increased across the experimental period. Finally, we evaluated the activity of a synthetic blend of these chemicals by performing bioassays which demonstrated the same attractive effect in males only. The results confirm that female H. axyridis produce a volatile sex pheromone. These findings have potential in the development of more specific and efficient biological pest-control management methods aimed at manipulating the behavior of this invasive lady beetle. [less ▲]

Detailed reference viewed: 42 (2 ULg)
See detailMarcello Venusti nel mondo di Perino del Vaga
Geremicca, Antonio ULg

Conference (2015, May 12)

Detailed reference viewed: 10 (1 ULg)
See detailRemote sensing of the atmospheric composition in the infrared spectral region within the Network for the Detection of Atmospheric Composition Change (NDACC) and the Total Carbon Column Observing Network (TCCON)
Notholt, J; Blumenstock, T; Deutscher, N et al

Conference (2015, May 12)

Remote sensing has been established as a powerful tool in atmospheric research. Throughout the last decades satellite and ground-based remote sensing instruments and methods have been developed to sample ... [more ▼]

Remote sensing has been established as a powerful tool in atmospheric research. Throughout the last decades satellite and ground-based remote sensing instruments and methods have been developed to sample the atmosphere from the microwave to the UV/Vis. The international ground based networks NDACC-IR and TCCON are based on solar absorption spectrometry in the infrared. Both networks consist of more than 30 observations sites around the globe, from the high Arctic through mid-latitudes and the tropics to the southern hemisphere and Antarctica. NDACC concentrates on stratospheric observations in relation to ozone chemistry, in many instances, information on the vertical distribution of the target species is determined. Measured trace gases include O3, HCl, HF, HNO3, ClONO2 and many others. In addition, the tropospheric composition is studied by measuring anthropogenic and biogenic species including HCN, OCS, H2O, CO, CH2O, C2H6, and C2H2. The aim of TCCON is to acquire accurate and precise column-averaged abundances of CO2, CH4, N2O, i.e. atmospheric trace gases which have a very small natural variability. TCCON measurements are linked to WMO calibration scales by comparisons with co-incident in situ profiles measured from aircraft or balloon. Results from both networks have been used in many studies in relation to stratospheric ozone chemistry, air-pollution, and with regard to the carbon-cycle. Long-term series are necessary for trend analysis, gaining insight into annual and longer term variability and placing into context shorter term process studies. Due to the similar observation geometry, the ground-based observations are optimally suitable for satellite and model validation and form an essential part of many satellite projects. They also play an important role in the validation of the Copernicus Atmospheric Monitoring Service. In our contribution we will give an overview on the current status of both networks, ongoing efforts to improve network coverage, precision and accuracy, and several examples of scientific highlights. [less ▲]

Detailed reference viewed: 33 (0 ULg)
Full Text
See detailOn the nature of cosmological time
Hauret, Clémentine ULg

Conference (2015, May 11)

Detailed reference viewed: 8 (2 ULg)
See detailIntroduction
Cormann, Grégory ULg

Conference (2015, May 11)

Detailed reference viewed: 18 (2 ULg)
Full Text
See detailTiO2 templated films used as photoelectrode for solid-state DSSC applications: Study of the solid electrolyte infiltration by Rutherford Backscattering Spectrometry
Dewalque, Jennifer ULg; Colson, Pierre ULg; Mathis, François et al

Poster (2015, May 10)

Liquid-state dye-sensitized solar cells can suffer from electrolyte evaporation and leakage. Therefore solid-state hole transporting materials are investigated as alternative electrolyte materials ... [more ▼]

Liquid-state dye-sensitized solar cells can suffer from electrolyte evaporation and leakage. Therefore solid-state hole transporting materials are investigated as alternative electrolyte materials. However, in solid-state dye-sensitized solar cells, optimal TiO2 films thickness is limited to a few microns allowing the adsorption of only a low quantity of photoactive dye and thus leading to poor light harvesting and low conversion efficiency. In order to overcome this limitation, high surface area templated films are investigated as alternative to nanocrystalline films prepared by doctor-blade or screen-printing. Moreover, templating is expected to improve the pore accessibility what would promote the solid electrolyte penetration inside the porous network, making possible efficient charge transfers. In this study, films prepared from different structuring agents are discussed in terms of microstructural properties (porosity, crystallinity) as well as effect on the dye loading and Spiro-OMeTAD (2,2',7,7'-tetrakis-(N,N-di-p-methoxyphenylamine)9,9'-spirobifluorene) solid electrolyte filling. Different techniques such as transmission electron microscopy (TEM), atmospheric poroellipsometry (AEP) and UV-visible absorption spectroscopy (UV-vis.) have been used to describe the microstructural features of the films. Besides, we have implemented Rutherford backscattering spectrometry (RBS) as an innovative non-destructive tool to characterize the hole transporting materials infiltration. Templated films show dye loading more than two times higher than nanocrystalline films prepared by doctor-blade or screen-printing and solid electrolyte infiltration up to 88%. [less ▲]

Detailed reference viewed: 34 (3 ULg)
Full Text
See detailPrevention of Synovial Membrane Inflammation & Cartilage Degradation by a Novel Chitosan
Henrotin, Yves ULg; Oprenyeszk, Frédéric ULg; Dubuc, Jean-Emile et al

Conference (2015, May 10)

Detailed reference viewed: 12 (1 ULg)
Full Text
See detail"Drôleries". L'iconographie marginale des portails occidentaux et de la nef de la cathédrale de Strasbourg
Van den Bossche, Benoît ULg

Conference (2015, May 09)

Le vaste ensemble sculpté constitué par les trois portails occidentaux de la cathédrale de Strasbourg a fait l’objet, ces dernières années, de plusieurs études. Une critique d’authenticité a été menée ... [more ▼]

Le vaste ensemble sculpté constitué par les trois portails occidentaux de la cathédrale de Strasbourg a fait l’objet, ces dernières années, de plusieurs études. Une critique d’authenticité a été menée ; les choix iconographiques qui ont présidé à l’élaboration du programme ont été déterminés et justifiés. Toutes ces études ont pourtant laissé de côté une centaine de reliefs finement sculptés qui agrémentent les parties hautes du niveau des portails, à l’extérieur comme à l’intérieur de la façade. Cette iconographie, authentique pour l’essentiel, se distingue par une grande variété de « sujets ». A priori, elle rappelle celle des « drôleries » des manuscrits de la fin du XIIIe siècle et du XIVe. Mais est-ce le cas ? Et si c’est le cas, comment articuler ces sujets qui ont jusqu’à aujourd’hui été considérés comme marginaux, avec l’iconographie des ébrasements, des tympans et des voussures ? Enfin, l’ensemble de « drôleries » de la cathédrale de Strasbourg peut-il, d’un point de vue iconographique, être comparé à d’autres ensembles sculptés français et germaniques de la fin du XIIIe siècle et du XIVe ? [less ▲]

Detailed reference viewed: 13 (1 ULg)
Full Text
See detailRADIOPHARMACY GMP QC HPLC VALIDATION
Aerts, Joël ULg; Giacomelli, Fabrice ULg; Hubert, Philippe ULg et al

Conference (2015, May 09)

Detailed reference viewed: 20 (4 ULg)
Full Text
Peer Reviewed
See detailPartial volume effect impact on PET preclinical dosimetry: a simulation study
Seret, Alain ULg; Bahri, Mohamed Ali ULg; Bretin, Florian et al

Conference (2015, May 09)

Detailed reference viewed: 15 (2 ULg)
Peer Reviewed
See detailLe travail de la figurine ou l'effet de présence en question. Notes sur les films de marionnettes d’Émile Cohl
Tomasovic, Dick ULg

Conference (2015, May 08)

Etude de l'invention du régime visuel de la figurine à travers les films de marionnettes d'Emile Cohl.

Detailed reference viewed: 8 (0 ULg)
Full Text
See detailThe seamod.ro operational stochasting Black Sea forecasting system
Vandenbulcke, Luc ULg; Capet, Arthur; Grégoire, Marilaure ULg et al

Poster (2015, May 08)

Detailed reference viewed: 16 (3 ULg)
Full Text
Peer Reviewed
See detailGrammaire matérielle et erreur de catégorie
Leclercq, Bruno ULg

Conference (2015, May 08)

Detailed reference viewed: 20 (0 ULg)
See detailPrésentation de ModerNum
Regibeau, Julien ULg; Simon, Nicolas; Guri, Shipé

Conference (2015, May 08)

Detailed reference viewed: 17 (2 ULg)
Peer Reviewed
See detailTraduction et représentation politique : quelques éléments pour une genèse de leur rapport et de leur pertinence comme outils d’analyse politique
Smette, Bernard ULg

Conference (2015, May 08)

J’interrogerai la problématique du rapport de la traduction à la politique à partir de la notion de représentation politique, telle que thématisée par le théoricien argentin de l’analyse de discours ... [more ▼]

J’interrogerai la problématique du rapport de la traduction à la politique à partir de la notion de représentation politique, telle que thématisée par le théoricien argentin de l’analyse de discours, Ernesto LACLAU. Je commencerai très brièvement par resituer le processus de représentation dans le champ politique actuel. Cette re-contextualisation permettra de montrer que les notions de « représentation » et de « politique » entretiennent un rapport privilégié, mais qui ne se limite pas uniquement à sa forme contemporaine la plus répandue, symbolisée par nos institutions et principes politiques, tels le régime parlementaire ou encore l’élection. Je passerai alors au cœur de ma communication en dessinant la proximité conceptuelle et fonctionnelle de la traduction et de la représentation. Je me baserai, pour ce faire, sur les développements qu’Ernsto LACLAU a proposés de cette dernière, ainsi que sur quelques développements de Jean-René LADMIRAL et Willard Van Orman QUINE au sujet de la traduction. Je montrerai notamment (1) en quoi la conception de la représentation que propose LACLAU est un outil d’analyse pertinent de la politique, mais surtout (2) en quoi cette conception de la représentation est guidée par des processus traductifs. Je tenterai enfin, en guise de conclusion, de montrer en quoi l’on peut dégager de ce qui précède une perspective d’analyse supplémentaire, voire innovante, de l’articulation entre traduction, représentation et politique. [less ▲]

Detailed reference viewed: 16 (4 ULg)
Full Text
See detailLa médiation, un lien social à reconstruire.
Bachelet, Jean-François ULg

Conference (2015, May 08)

Detailed reference viewed: 23 (4 ULg)
Full Text
Peer Reviewed
See detailFast Userspace Packet Processing
Barbette, Tom ULg; Soldani, Cyril ULg; Mathy, Laurent ULg

in Proceedings of ANCS 2015 (2015, May 07)

In recent years, we have witnessed the emergence of high speed packet I/O frameworks, bringing unprecedented network performance to userspace. Using the Click modular router, we first review and ... [more ▼]

In recent years, we have witnessed the emergence of high speed packet I/O frameworks, bringing unprecedented network performance to userspace. Using the Click modular router, we first review and quantitatively compare several such packet I/O frameworks, showing their superiority to kernel-based forwarding. We then reconsider the issue of software packet processing, in the context of modern commodity hardware with hardware multi-queues, multi-core processors and non-uniform memory access. Through a combination of existing techniques and improvements of our own, we derive modern general principles for the design of software packet processors. Our implementation of a fast packet processor framework, integrating a faster Click with both Netmap and DPDK, exhibits up-to about 2.3x speed-up compared to other software implementations, when used as an IP router. [less ▲]

Detailed reference viewed: 164 (23 ULg)
See detail"Bon sens" et restrictions budgétaires
Counet, Maxime ULg

Conference (2015, May 06)

Detailed reference viewed: 14 (1 ULg)
Full Text
See detailProteome variations in Macrobrachium rosenbergii exposed to chlordecone: a gel-free proteomic approach
Lafontaine, Anne ULg; De Pauw, Edwin ULg; Forget-Leray, Joelle et al

Poster (2015, May 06)

Detailed reference viewed: 14 (4 ULg)
Full Text
Peer Reviewed
See detailSelf-defining memories and self-concept clarity: A comparative study of depressed patients, bipolar patients and healthy subjects
Wagener, Aurélie ULg; Boulanger, Marie ULg; Blairy, Sylvie ULg

Poster (2015, May 06)

Depressed and bipolar patients suffer from autobiographical memory (AM) deficits. For instance, depressed patients present an overgeneralisation and a mood congruence biases. Indeed, these patients seem ... [more ▼]

Depressed and bipolar patients suffer from autobiographical memory (AM) deficits. For instance, depressed patients present an overgeneralisation and a mood congruence biases. Indeed, these patients seem to have difficulties to recall specific and positive memories. The present study focusses on a particular kind of memories: the self-defining memories (SDMs). SDMs are highly pertinent for self-building: they help to define in the most clearly way our perception of ourselves. Because SDMs have not been studied a lot since yet in these two disorders, our goal is to assess the impact of general AM biases on SDMs. Then, the present study pursues two main aims: 1) To assess SDM’s characteristics, 2) To assess the relationship between SDM and self-concept clarity. To reach our objective, depressed and bipolar patients are compared to healthy subjects. Participants are asked to complete SDMs exercises that are recalling six important events which happened in their life. These SDMs are assessed on four variables: specificity, impact, meaning making, contain. Self-concept clarity and mood are also assessed. Until now, 17 depressed patients, 16 bipolar patients and 18 healthy controls participate in this study. Preliminary results do not highlight difference between our groups on specificity. Marginal effects appear for meaning making with healthy subjects recalling more meaning making events. Results show that depressed patients present a mood congruence. The final results will be presented during the convention, as data-collection is on-going and will end in April. Experimental and clinical implications of our results will be discussed. [less ▲]

Detailed reference viewed: 66 (0 ULg)
Full Text
Peer Reviewed
See detailEmbeddedness as a facilitator of sustainable entrepreneurship
Dufays, Frédéric ULg

Conference (2015, May 05)

This conceptual paper builds on stakeholder theory and the embeddedness argument to shift from the "what" to the "how" question on sustainable entrepreneurship. It shows that sustainable entrepreneurship ... [more ▼]

This conceptual paper builds on stakeholder theory and the embeddedness argument to shift from the "what" to the "how" question on sustainable entrepreneurship. It shows that sustainable entrepreneurship is a highly embedded process and that this high embeddedness facilitates the sustainability character of entrepreneurship. [less ▲]

Detailed reference viewed: 19 (1 ULg)
Full Text
See detailLes tabous à l’école : quelle place pour le juge en classe ?
Grandjean, Geoffrey ULg

Conference (2015, May 05)

L’objectif de la conférence est de revenir sur le concept de tabou en le liant à différents cas concrets rencontrés en milieu scolaire. L’exposé montre la place croissante accordée aux juges face à des ... [more ▼]

L’objectif de la conférence est de revenir sur le concept de tabou en le liant à différents cas concrets rencontrés en milieu scolaire. L’exposé montre la place croissante accordée aux juges face à des tabous qui suscitent des conflits. Une réflexion politologique est proposée par rapport au phénomène de judiciarisation. [less ▲]

Detailed reference viewed: 15 (2 ULg)
See detailIconic turn et critique du paradigme langagier
Hagelstein, Maud ULg

Conference (2015, May 05)

Je voudrais envisager ici le problème de la légalité des significations dans le champ non-verbal du visuel, tel qu’il est envisagé par un théoricien de l’image allemand actuel (G. Boehm). On pourrait en ... [more ▼]

Je voudrais envisager ici le problème de la légalité des significations dans le champ non-verbal du visuel, tel qu’il est envisagé par un théoricien de l’image allemand actuel (G. Boehm). On pourrait en effet dégager – selon la proposition de Boehm – un principe formel (au moins) qui structure l’émergence de significations dans le domaine du visuel. Boehm ne parle de grammaire à proprement parler que pour s’en écarter (il rejette l’usage de la grammaire prédicative pour la compréhension des images). [less ▲]

Detailed reference viewed: 20 (1 ULg)
Full Text
Peer Reviewed
See detailPsychological processes leading to activation or avoidance: Protective and vulnerability factors to depression
Wagener, Aurélie ULg

Conference (2015, May 05)

Kinderman (2005, 2013) elaborated a psychological model of mental ill-health according to which biological, social and circumstantial factors lead to mental disorders through their conjoint effects on ... [more ▼]

Kinderman (2005, 2013) elaborated a psychological model of mental ill-health according to which biological, social and circumstantial factors lead to mental disorders through their conjoint effects on psychological processes (PP). Our research adopted the same framework. It focused on PP which characterize depression. More precisely, since inactivity (also conceptualized as behavioural avoidance) is one of the main feature of depression, the present research focused on PP which influence the behavioural avoidance (vulnerability factor to depression) and the behavioural activation (protective factor for depression). Three main aims were pursued: To investigate the influence of the biased PP on the behavioural avoidance. To find the PP which have a positive influence on the behavioural activation. To present an integration of our results with Kinderman’s model. Four hundred seventy-seven community adults (358 women, 119 men; x ̅ age = 34.25, SD = 11.85) completed an online survey assessing PP (negative repetitive thoughts, emotion regulation strategies, environmental rewards, self-image, inhibition/approach), avoidance, activation and depression. Since several questionnaires were used to assess each PP, factorial scores were computed for each one. Overall, confirmatory factor analyses highlighted that avoidance is positively linked to ruminations, negative emotion regulation strategies and poor environmental rewards and that activation is positively linked to positive self-image and high environmental satisfaction. Results will also be discussed according to the sex. According to their influence on both avoidance and activation, the environmental reward and the emotion regulation strategies appear to be important variables to work on during the treatment of depression. [less ▲]

Detailed reference viewed: 45 (1 ULg)
Full Text
See detailTowards an extension of the catalogue of particle-accelerating colliding-wind binaries
De Becker, Michaël ULg

Conference (2015, May 05)

Particle-accelerating colliding-wind binaries (PACWBs) constitute a class of massive stars known to be able to accelerate charged particles up to relativistic velocities. The latter property is identified ... [more ▼]

Particle-accelerating colliding-wind binaries (PACWBs) constitute a class of massive stars known to be able to accelerate charged particles up to relativistic velocities. The latter property is identified mainly through the detection of synchrotron radiation in the radio domain, and in a few cases thanks to the detection of non-thermal radiation in the high energy domain. The catalogue of PACWBs contains about 40 objects, covering a wide parameter space in terms of stellar wind and orbital parameters. So far, there is no evidence for a strict criterion to justify the occurrence of a particle acceleration process only in a small fraction of the colliding-wind binaries population, admitting the possibility that it might be a frequent property among massive stars. In this contribution, I address the issue of the frequency of particle accelerators among massive binaries, and I discuss observation strategies aiming at identifying new members of the catalogue. [less ▲]

Detailed reference viewed: 20 (1 ULg)
Full Text
See detailHigher male than female recombination rate in cattle is controlled by genetic variants effective in both sexes
Kadri, Naveen Kumar ULg; Harland, Chad ULg; Coppieters, Wouter ULg et al

Poster (2015, May 05)

We herein study genetic recombination in three dairy cattle populations from France, New-Zealand and the Netherlands. We apply a new phasing algorithm extracting familial information suited for large half ... [more ▼]

We herein study genetic recombination in three dairy cattle populations from France, New-Zealand and the Netherlands. We apply a new phasing algorithm extracting familial information suited for large half-sib families to reconstruct haplotypes and detect cross-overs (CO). The software is robust to genotyping and map errors. We identify more than 2,000,000 CO events in sperm cells transmitted by 3008 sires to 94,603 offspring, and more than 500,000 CO events in oocytes transmitted by 11,497 cows to 25,390 offspring. When measured in identical family structures, the average number of CO in males (24.0) was found to be larger than in females (21.8). In males, recombination rates were higher closer to telomeres whereas in females, recombination rates dropped at both centromeres and telomeres (probably as a result of lower informativity). The heritability of the global recombination rate (GRR) was close to 0.20 in males and to 0.08 in females. Genetic correlation ranged from 0.38 to 0.69 depending on the population, indicating that shared variants are influencing GRR in both genders. Haplotype-based genome-wide association studies revealed four genome-wide significant QTL, including two previously identified ones (involving REC8 and RNF212). For all QTLs, there was a positive correlation between haplotype effects across sexes, ranging from 0.35 to 0.68. We selected two reference panels of respectively 122 and 215 bulls sequenced at cover > 15x to impute variants in the New-Zealand and French populations. All variants identified by next-generating sequencing in 5 Mb windows encompassing the QTL peaks were imputed with Beagle in order to perform a sequence-based association study. For three QTLs, we identified missense mutations in genes known to be involved in meiosis among the most significantly associated variants. These variants were perfectly associated with the haplotypes underlying the QTL effects. The variant identified in RNF212 had already been reported, whereas missense mutations in MLH3 (N408S) and HFM1 (S1189L) are new findings. Surprisingly, variants previously identified in REC8 did not capture the QTL effect whereas variants in RNF212B, PPP1R3E, BCL2L2, HOMEZ and PABPN1 had much stronger association with the phenotype. The three missense mutations were significant in both genders with two of them accounting for approximately 10% of the genetic variance in males (the allelic substitution effect being approximately equal to one additional CO per genome). Our results are very different from reports of recombination in other species. For instance, in human, recombination rate is higher in females, distinct variants affect recombination rate in males and females and the genetic correlation is close to 0 whereas in cattle, we observed a higher recombination rate in males controlled by shared variants effective in both sexes. [less ▲]

Detailed reference viewed: 18 (0 ULg)
Full Text
See detailUse of GEOS-Chem for the interpretation of long-term FTIR measurements at the Jungfraujoch and other NDACC sites
Mahieu, Emmanuel ULg; Bovy, Benoît ULg; Bader, Whitney ULg et al

Poster (2015, May 04)

We present recent and ongoing investigations using 3D CTM GEOS-Chem model simulations for the interpretation of long-term FTIR measurements performed at selected NDACC sites.

Detailed reference viewed: 18 (10 ULg)
Peer Reviewed
See detailThe crucial role of soil when modelling the impact of climate change on crop production
Basso, Bruno; Dumont, Benjamin ULg; Shcherbak, Iurii et al

in Shirmohammadi, Adel; Bosch, David; Muñoz-Carpena, Rafa (Eds.) Proceedings of the 1st ASABE Climate Change Symposium - Adaptation and Mitigation (2015, May 03)

Detailed reference viewed: 43 (6 ULg)
See detailCarbon dioxide, a cheap bio-sourced building block for cyclic carbonates and non-isocyanate polyurethanes
Gennen, Sandro ULg; Alves, Margot ULg; Tassaing, Thierry et al

Poster (2015, May 03)

Due to concerns about global warming combined with the decrease of fossil resources, new carbon feedstocks that are abundant, renewable, non-toxic, inexpensive and environmentally friendly must be ... [more ▼]

Due to concerns about global warming combined with the decrease of fossil resources, new carbon feedstocks that are abundant, renewable, non-toxic, inexpensive and environmentally friendly must be explored to produce chemicals. Besides the valorization of bio-based raw materials, the chemical transformation of carbon dioxide into added-value products has gained interest in both academia and industry. To date, the chemical fixation of CO2 onto epoxides with the formation of cyclic carbonates is one of the most promising ways to valorize CO2 at an industrial scale. Indeed, cyclic carbonates find applications as electrolytes in lithium ion batteries, as aprotic polar solvents or as useful intermediates for polycarbonates. Cyclic carbonates also react with primary amines to produce 2-hydroxyethylurethane. This reaction can be extrapolated to the synthesis of non-isocyanate polyurethanes (NIPU) by polyaddition of bifunctional cyclic carbonates with diamines.5 This study aims (i) at developing a new highly efficient organocatalyst for the synthesis of cyclic carbonates under mild experimental conditions and (ii) their valorization as monomers to produce non-isocyanate polyurethanes. First, we have identified a bicomponent organocatalyst, composed of a judicious combination of an organocatalyst and an activator, for the very fast synthesis of cyclic carbonates from CO2 and epoxides under very mild reaction conditions. Kinetics of reactions were followed by online Raman spectroscopy measurements under pressure. NMR titrations were realized to evidence the mechanism of activation of this novel organocatalytic system that will be discussed in detail in this talk. The second objective relies on the development of new efficient organocatalysts for the synthesis of high molar masses NIPUs in short reaction times. Organic compounds interacting with the cyclic carbonate by hydrogen bonding were identified and their catalytic activity was demonstrated for model compounds. [less ▲]

Detailed reference viewed: 73 (1 ULg)
Peer Reviewed
See detailModeling of Antimicrobial Lipopeptides in interaction with lipidic membranes
Loison, Claire; Nasir, Mehmet Nail ULg; Besson, Françoise et al

Conference (2015, May)

Detailed reference viewed: 10 (0 ULg)
Full Text
See detailPatch types in Posidonia oceanica meadows around Corsica. How can we use them in seascape ecology?
Abadie, Arnaud ULg; Bonacorsi, Marina; Gobert, Sylvie ULg et al

Conference (2015, May)

The meadows formed by the Mediterranean seagrass Posidonia oceanica are subjected to various natural (e.g., water movement, light availability, sedimentation) and anthropogenic (e.g., anchoring, trawling ... [more ▼]

The meadows formed by the Mediterranean seagrass Posidonia oceanica are subjected to various natural (e.g., water movement, light availability, sedimentation) and anthropogenic (e.g., anchoring, trawling, fish farms, explosives) phenomena that erode them and create diverse types of patches. The assemblage of the P. oceanica matrix and these patches creates particular seascapes. On the basis of this assessment, we aimed to investigate the importance of the patch type in structuring P. oceanica seascapes and to offer new prospects in the large scale studies of seagrass meadows. Five sites encompassing large P. oceanica meadows ranging from 1.86 km² to 4.42 km² along the Corsican coast (France) were considered. Eleven patch types with different sizes, shapes and origins were identified using side scan sonar images (sonograms). Five were recognized as natural and five as anthropogenic. One can be of both origins. The resolution of the sonograms allowed to detect patches of various sizes ranging from 1 m² to 111 829 m². The relation between structural characteristics of patches and the whole seascape aspect was explored using seven landscape metrics relevant for the study of meadows patchiness (patch area, mean radius of gyration, area-weighted radius of gyration, coefficient of variation of the Euclidean nearest-neighbor distance, area-weighted perimeter-area ratio, landscape division index, number of patches). Only a small number of patch types appears to play the strongest role in the characterization of the P. oceanica seascapes. Furthermore, the use of seascape structures seems to be suitable for the development of new tools like indices for the assessment of human impacts on P. oceanica meadows. In this perspective we propose a new and simple index, the Patchiness Source Index (PaSI), to estimate the origin of the patchiness (natural or anthropogenic) for a given area. A landscape approach, as well as information on patch dynamic, should be integrated in the new indices that aim to assess the state of conservation of the whole P. oceanica ecosystem. [less ▲]

Detailed reference viewed: 22 (3 ULg)
Peer Reviewed
See detailRocking behaviour of simple unreinforced load-bearing masonry walls including soundproofing rubber layers
Mordant, Christophe ULg; Denoël, Vincent ULg; Degée, Hervé

in Proceedings of 5th ECCOMAS Thematic Conference on Computational Methods in Structural Dynamics and Earthquake Engineering (2015, May)

This paper compares experimental measurements with predictions of different rocking models. These comparisons are carried out on the base of recent experimental results obtained by shake-table tests of ... [more ▼]

This paper compares experimental measurements with predictions of different rocking models. These comparisons are carried out on the base of recent experimental results obtained by shake-table tests of four simple unreinforced load-bearing clay masonry walls that have exhibited a significant rocking behaviour for the highest acceleration inputs. In a first stage, the simple model proposed by Housner is used after slight modifications needed to properly consider the actual mass distribution. Two parameters are identified as governing the model response, namely the criterion defining the initiation of motion and the restitution coefficient. Then, a two stacked blocks model is developed and solved by an event-driven strategy. This two-block model is intended to allow a better description of the behaviour of tested specimens through a more precise modelling of the additional mass. Finally, the pres-ence of rubber layers positioned at the top and bottom of two of the tested walls with the pur-pose of improving their acoustic behaviour required the development of an updated rocking model with viscous and flexible interfaces at the base of the wall and between the two stacked blocks. The properties of these interfaces are deduced from experimental data and their sig-nificant influence on the response is evidenced. [less ▲]

Detailed reference viewed: 19 (3 ULg)
Full Text
Peer Reviewed
See detailBeam to concrete-filled rectangular hollow section column joints using long bolts
Hoang, Van Long ULg; Demonceau, Jean-François ULg; Jaspart, Jean-Pierre ULg

in Proceedings of the 15th international symposium on tubular structures - ISTS15 (2015, May)

This paper presents a research on a specific type of unstiffened extended end-plate joint used to connect I-shaped beams to concrete-filled rectangular hollow section columns. The main idea is to use long ... [more ▼]

This paper presents a research on a specific type of unstiffened extended end-plate joint used to connect I-shaped beams to concrete-filled rectangular hollow section columns. The main idea is to use long bolts throughout the column to connect the beam end-plates, so avoiding intermediate connecting elements (e.g. a reverse U channel) or special bolts (e.g. blind bolts). However, the use of long bolts for beam-to-column connections is still rare in the construction and no design procedure exists in the Eurocodes; this justifies the pre-sent research. Firstly, a test program within a RFCS European project titled HSS-SERF “High Strength Steel in Seismic Resistant Building Frames”, 2009-2013 was performed. In this project, specimens subjected to sig-nificant bending moments (and shear) or to shear only was defined. Then, analytical developments based on the component approach and aimed at predicting the joint response have been carried out; their validity is demonstrated through comparisons with the tests. Finally, design guidelines have been provided. [less ▲]

Detailed reference viewed: 50 (9 ULg)
Full Text
Peer Reviewed
See detailBiscuits et thé à la menthe aux fêtes interculturelles. Entre essentialisation et participation des femmes marocaines en Italie.
Mescoli, Elsa ULg

Conference (2015, May)

Cette communication est issue d’une recherche ethnographique autour des pratiques culinaires d’un groupe de femmes marocaines résidentes dans une ville de la province de Milan, en Italie. Le matériel ... [more ▼]

Cette communication est issue d’une recherche ethnographique autour des pratiques culinaires d’un groupe de femmes marocaines résidentes dans une ville de la province de Milan, en Italie. Le matériel collecté au sein des entretiens et des observations a permis d’étudier d’un côté la définition des sujets au travers des pratiques alimentaires, d’un autre côté leur modalité de prendre part à la vie sociale locale. Grâce aux activités de la vie quotidienne, une appartenance culturelle et religieuse peut être affirmée, en permettant ainsi la revendication du « droit à la diversité ». La performance publique des pratiques culinaires permet aux femmes considérées d’exercer une agency à l’intérieur des espaces institutionnellement concédés à l’expression des migrants. Lors des fêtes interculturelles, les rituels d’une sorte de « cannibalisme exogène » se mettent en place : la population majoritaire, en goûtant les plats des Autres, incorpore la diversité afin de la contrôler. Néanmoins, les femmes migrantes en charge des préparations choisissent activement quels ingrédients (du soi et des plats) faire consommer, en présentant ainsi certains aspects qui vont au-delà de la culture alimentaire. Le partage de nourriture leur permet d’assumer un rôle actif dans la communauté locale, tout en affirmant leurs propres spécificités. Les femmes considérées acquièrent une position politiquement importante au sein de la société et sont ainsi légitimées à participer aux débats et décisions autour de certains questions clefs de la pratique de la diversité. [less ▲]

Detailed reference viewed: 22 (2 ULg)
Full Text
Peer Reviewed
See detailTrace element contamination severity of coastal waters: A first bioassessment at the scale of the whole Mediterranean Sea
Richir, Jonathan ULg; Salivas-Decaux, Maylis; Lafabrie, Céline et al

in PeerJ (2015, May)

Human activities generate large volumes of waste that supply marine coastal environments in pathogens, organic matter, nutrients and toxicants. Among the wide range of toxicants are trace elements. Since ... [more ▼]

Human activities generate large volumes of waste that supply marine coastal environments in pathogens, organic matter, nutrients and toxicants. Among the wide range of toxicants are trace elements. Since the latter are toxic for aquatic organisms from threshold levels and as they are therefore likely to cause multiple damage to the population, the community and the ecosystem levels, their environmental occurrence has to be accurately monitored in order to guarantee appropriate environmental management of coastal zones and to preserve marine coastal ecosystems and the goods and services they provide. In the framework of the STARECAPMED project, the present study aimed to monitor, for the first time, the coastal contamination of the entire Mediterranean by As, Ag, Cd, Cu, Hg, Ni and Pb, using Posidonia oceanica (L.) Delile as bioindicator species. But sustainable coastal management also requires the development of appropriate contamination classification systems intended, among other purposes, for environmental managers and policy makers. The combined utilization of several complementary monitoring tools, i.e. water quality scale, pollution index (TEPI and TESVI) and spatial analysis (PCA, CA, correlation analysis and GIS mapping) successfully led to the development of an operational classification system of this kind. In particular, the mapping of the trace element contamination according to a new proposed 5-level water quality scale using the quantile method precisely outlined the contamination severity along Mediterranean coasts and facilitated interregional comparisons. The reliability of the use of P. oceanica as bioindicator species was further again demonstrated through several global, regional and local detailed case studies. In conclusion, holistic approaches such as developed in the present study should be privileged to accurately monitor the contamination rate of coastal waters and to transfer relevant information on this composite problem to environmental managers and policy makers. [less ▲]

Detailed reference viewed: 17 (2 ULg)
Full Text
See detailStrategies of regioselective radiolabeling of Nanofitin binder for imaging
Goux, Marine ULg; Dammicco, Sylvestre ULg; Becker, Guillaume ULg et al

Poster (2015, May)

Recently, new strategies emerged in the field of monoclonal antibodies radiolabeling for PET imaging with the use of positron emitter such as fluorine-18, zirconium-89 or gallium-68. Despite their ... [more ▼]

Recently, new strategies emerged in the field of monoclonal antibodies radiolabeling for PET imaging with the use of positron emitter such as fluorine-18, zirconium-89 or gallium-68. Despite their important role in the therapeutic world, antibodies have many disadvantages related to their structure. Moreover, conjugation of chelating agent often occurs on lysines, which is non-regioselective and leads to a heterogeneous mixture of products. In addition, the slow clearance of antibodies can be a problem to obtain a good contrast when they are used in imaging. To address these different limitations, we developed a chemistry-free chelating system consisting of a highly phosphorylatable peptide tag fused genetically to a Nanofitin. A specific phosphorylation step, with the alpha subunit of the casein kinase II, generates a nanocluster of 4 phosphates that can interact strongly with metal ion like zirconium or gallium. This strategy has already demonstrated its powerfulness for the stable and specific anchoring of protein on zirconium phosphonate-based microarray [1]. Considering this tag has been created to specifically anchoring protein on zirconium phosphonate-based microarray, we are currently working on a sequence derived from calcium-binding proteins to chelate specifically lanthanides[2]. As described by Pardoux et al.[3], our strategy is to functionalize this sequence with a phosphate nanocluster able to chelate zirconium or gallium. Our first results shown that a mono-phosphorylatable tag phosphorylated in vitro is able to chelate terbium(III) with a lower affinity than the wild type. Considering that terbium(III) is bigger than gallium(III) or zirconium(IV), we can suppose that the cage obtained is too small but suitable for other ions. In order to validate our hypothesis, we have planned to radiolabel those tags and determine their affinity for gallium(III). In order to validate the use of Nanofitin as a potent alternative tool for in vivo imaging, we have made biokinetic studies in mice with PET and MRI imaging. In these studies, we have radiolabelled with fluorine-18 a Nanofitin and we are currently making use of its specific binding to a cell-surface receptor to target a very precise cell population by using an animal model. Once the phosphorylatable tag optimized for regioselective radiolabelling and the Nanofitin targeting validated in an animal model, the next steps will be to combine these two approaches: we will fuse genetically the tag to the specific Nanofitin, radiolabel it with gallium-68 and perform the biokinetic study of this new radiopharmaceutical product. [1] M. Cinier, M. Petit, F. Pecorari, D. R. Talham, B. Bujoli, and C. Tellier, “Engineering of a phosphorylatable tag for specific protein binding on zirconium phosphonate based microarrays.,” J. Biol. Inorg. Chem., vol. 17, no. 3, pp. 399–407, Mar. 2012. [2] L. J. Martin, “Development of Lanthanide-Binding Tags (LBTs) as powerful and versatile peptides for use in studies of proteins and protein interactions,” 2008. [3] R. Pardoux, S. Sauge-merle, D. Lemaire, P. Delangle, L. Guilloreau, J. Adriano, and C. Berthomieu, “Modulating Uranium Binding Affinity in Engineered Calmodulin EF-Hand Peptides : Effect of Phosphorylation,” PLoS One, vol. 7, no. 8, 2012. [less ▲]

Detailed reference viewed: 22 (4 ULg)