References of "Scientific congresses and symposiums"
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See detailTowards a normalised 3D Geovisualisation : the viewpoint management
Neuville, Romain ULg; Poux, Florent ULg; Hallot, Pierre ULg et al

in ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences (2016, October 05), IV-2(W1), 179-186

This paper deals with the viewpoint management in 3D environments considering an allocentric environment. The recent advances in computer sciences and the growing number of affordable remote sensors lead ... [more ▼]

This paper deals with the viewpoint management in 3D environments considering an allocentric environment. The recent advances in computer sciences and the growing number of affordable remote sensors lead to impressive improvements in the 3D visualisation. Despite some research relating to the analysis of visual variables used in 3D environments, we notice that it lacks a real standardisation of 3D representation rules. In this paper we study the “viewpoint” as being the first considered parameter for a normalised visualisation of 3D data. Unlike in a 2D environment, the viewing direction is not only fixed in a top down direction in 3D. A non-optimal camera location means a poor 3D representation in terms of relayed information. Based on this statement we propose a model based on the analysis of the computational display pixels that determines a viewpoint maximising the relayed information according to one kind of query. We developed an OpenGL prototype working on screen pixels that allows to determine the optimal camera location based on a screen pixels colour algorithm. The viewpoint management constitutes a first step towards a normalised 3D geovisualisation. [less ▲]

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See detailSMART POINT CLOUD: DEFINITION AND REMAINING CHALLENGES
Poux, Florent ULg; Neuville, Romain ULg; Hallot, Pierre ULg et al

in ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences (2016, October 05), IV-2(W1), 119-127

Dealing with coloured point cloud acquired from terrestrial laser scanner, this paper identifies remaining challenges for a new data structure: the smart point cloud. This concept arises with the ... [more ▼]

Dealing with coloured point cloud acquired from terrestrial laser scanner, this paper identifies remaining challenges for a new data structure: the smart point cloud. This concept arises with the statement that massive and discretized spatial information from active remote sensing technology is often underused due to data mining limitations. The generalisation of point cloud data associated with the heterogeneity and temporality of such datasets is the main issue regarding structure, segmentation, classification, and interaction for an immediate understanding. We propose to use both point cloud properties and human knowledge through machine learning to rapidly extract pertinent information, using user-centered information (smart data) rather than raw data. A review of feature detection, machine learning frameworks and database systems indexed both for mining queries and data visualisation is studied. Based on existing approaches, we propose a new 3-block flexible framework around device expertise, analytic expertise and domain base reflexion. This contribution serves as the first step for the realisation of a comprehensive smart point cloud data structure [less ▲]

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See detailMise en place de pratiques agricoles de conservation: quel impact sur la vie du sol
Degrune, Florine ULg; Boeraeve, Fanny ULg; Vandenbol, Micheline ULg et al

Poster (2016, October 04)

Le projet Farm4Future a été lancé en 2015 et consiste en un suivi intégré d’un réseau d’exploitations agricoles belges en cours de transition vers des pratiques dites « de conservation ». Les ... [more ▼]

Le projet Farm4Future a été lancé en 2015 et consiste en un suivi intégré d’un réseau d’exploitations agricoles belges en cours de transition vers des pratiques dites « de conservation ». Les exploitations étudiées dans le cadre de ce projet sont caractérisées par des changements de gestion incluant notamment : (1) des associations de culture, (2) des couverts permanents, (3) une réduction du travail du sol et (4) l’introduction de structures vertes telles que les haies ou les bandes fleuries. Afin d’évaluer le potentiel agronomique et écologique de ces systèmes agricoles, une série de mesures ont été effectuées dans deux types de sol aux propriétés texturales contrastées : sable limoneux et un limon sableux. Afin d’obtenir un point de comparaison, les mêmes mesures ont été effectuées sur les parcelles des agriculteurs voisins restés en intensif et conventionnel. Parmi ces mesures, nous étudions la réponse de plusieurs indicateurs biologiques de qualité des sols telle que la diversité microbienne. L’étude a démontré un effet du type de pratiques agricoles sur la diversité microbienne en fonction du type de sol. Nous avons également identifié les microorganismes sensibles au type de pratiques agricoles. Cependant, l’étude nous amène à démontrer une grande hétérogénéité de réponses au sein de chacun de ces groupes. En effet, même si certains grands groupes sont globalement plus abondants sous pratiques de conservation (ou conventionnel), la réponse des microorganismes au sein de ces groupes à des niveaux taxonomiques plus fins (genre ou espèce) n’est pas uniforme. Aujourd’hui, même si les outils moléculaires de séquençage à haut débit ont permis de mettre en lumière l’incroyable diversité microbienne des sols, les services écosystémiques rendus par ces microorganismes sont encore très peu connus car moins de 1% des organismes est cultivable en laboratoire. [less ▲]

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See detailThe functional-biogeography of the reef fishes in the Gulf of California: over-importance of a handful of sites
Olivier, Damien ULg; Reyes Bonilla, Hector

Poster (2016, October 03)

Functional biogeography is a new discipline allowing to link biogeographical patterns of trait and species diversity. This new area of research has a role in conservation policy because it permits to ... [more ▼]

Functional biogeography is a new discipline allowing to link biogeographical patterns of trait and species diversity. This new area of research has a role in conservation policy because it permits to create functional maps to highlight hotspots of biodiversity. In this study, we evaluate the taxonomic and functional diversity of the reef-fishes in 30 “archipelagoes” widespread along the Gulf of California (GOC). The question before us is to highlight areas requiring a particular intention in conservation policy because they represent a large part of the legacy of reef-fish diversity in the GOC. To do so, we used a recently developed method to classify the reef-fishes species of the GOC in functional entities (FEs). The FEs are based on unique combinations of six categorical traits known to influence the functional role of fishes (e.g. size, diet…) and their number represent the level of functional diversity of the community. The results showed that the Baja California Sur has the most diversified reef-fishes community, both taxonomically and functionally (more than 90% of the species and of the functional diversity are represented). This result is mainly due to four archipelagoes that present a dazzling diversity, i.e. Carmen, San José, Espiritu Santo and Cerralvo. Each of these islands includes 60% or more of the taxonomic and functional diversity of the GOC. Two of these archipelagoes benefit of a protection level through the National Parks of Loreto and Espiritu Santo. However, the former is poorly functioning and the latter is under evaluation. The outcomes of the present study provide a global map of the reef-fishes diversity through the GOC, in term of species number and functional diversity. These results allow the identification of four major hotspots of diversity that should require a particular attention to preserve the legacy of reef-fishes diversity in the GOC. [less ▲]

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See detailThe OD/OH Isotope Ratio in Comets 8P/Tuttle and C/2012 F6 (Lemmon)
Rousselot, Philippe; Jehin, Emmanuel ULg; Hutsemekers, Damien ULg et al

in Bulletin of the American Astronomical Society (2016, October 01), 48

The determination of isotopic ratios in solar system objects is an important source of information about their origin, especially for comets. Among these ratios the D/H is of particular importance because ... [more ▼]

The determination of isotopic ratios in solar system objects is an important source of information about their origin, especially for comets. Among these ratios the D/H is of particular importance because of its sensitivity to fractionation processes and physical environment, and the abundance of hydrogen in the solar system. The main molecule used to derive this ratio in comets is water. So far, apart water, only HCN has permitted to derive D/H ratio and not only upper limits.Most of the existing determinations of D/H in water molecules have been obtained by spectroscopic observations of water lines in the sub-mm or near infrared range [1,2]. So far only one measurement has been based on OD/OH emission lines radicals in the near-UV [3] and another one on the Lyman-alpha D emission [4]. In situ measurements have also been obtained in comets 1P/Halley and 67P/Churyumov-Gerasimenko using mass spectrometer [5,6,7,8].In this work we have used the OH and OD ultraviolet bands at 310 nm observed with the ESO 8-m Very Large Telescope feeding the Ultraviolet-Visual Echelle Spectrograph (UVES) for measuring the D/H ratio in comets 8P/Tuttle and C/2012 F6 (Lemmon). The OH and OD being the photodissociation products of H[SUB]2[/SUB]O and HDO such observations allow to derive D/H ratio for water molecules. This work constitutes an independant determination of the D/H ratios already published for these comets and based on observations performed in the sub-mm and near infrared range of H[SUB]2[/SUB]O and HDO lines. We present our modeling, data analysis and numerical values obtained for this ratio.[1] D. Bockelée-Morvan et al., 2015, SSR 197, 47-83 [2] N. Biver et al., 2016, A&A 589, id A78, 11p [3] D. Hutsemékers et al., 2008, A&A 490, L31 [4] H.A. Weaver et al., 2008, LPI Contributions 1405, 8216 [5] H. Balsiger, K. Altwegg, J. Geiss, 1995, JGR 100, 5827 [6] P. Eberhardt et al., 1995, A&A 302, 301 [7] R.H. Brown et al., 2012, PSS 60, 166 [8] K. Alwegg et al., 2015, Science 347, article id. 1261952 [less ▲]

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See detailOPTIMIZATION OF A FULLY AUTOMATED ELECTROPHORETICALLY MEDIATED MICROANALYSIS SYSTEM FOR CYP1A1 ACTIVITY MONITORING
Farcas, Elena ULg; Servais, Anne-Catherine ULg; Lamalle, Caroline et al

Conference (2016, October 01)

Objective of the study Since CYP1A1, a member of cytochrome P450 superfamily, has been described to be over expressed in various types of cancer, our study was focused on the optimization of a fully ... [more ▼]

Objective of the study Since CYP1A1, a member of cytochrome P450 superfamily, has been described to be over expressed in various types of cancer, our study was focused on the optimization of a fully automated system for the monitoring of this particularly interesting enzyme. Moreover, the potentiality of this approach to screen CYP1A1 inhibitors was investigated. Materials and methods The experiments were carried out on a HP3DCE system using an on-column DAD. The EMMA procedure was performed by injecting a plug containing the co-factor(NADPH) and the substrate(7-ethoxycoumarin) between two plugs of CYP1A1 supersomes. The reaction was triggered by the application of a voltage switch. The voltage was then turned off to allow the metabolic reaction to occur. The separation of the components was then performed. Results Satisfying results were obtained using CYP1A1 at a concentration of 200 pmol/mL, while the incubation time was settled to 15 min. A DoE was performed to find the best mixing conditions. The amount of metabolite obtained was comparable to the one detected after conventional off-line metabolization. The ability of our system to monitor CYP1A1 inhibition was then proven with apigenin, a well-known CYP1A1 inhibitor. Conclusions The present study describes the development of a fully automatized in-capillary method for CYP1A1 activity monitoring and proves the potentialy of our system to be used for the screening of CYP1A1 inhibitors. The advantages of performing inline metabolization assays are mainly the miniaturization and the automatization of the process. Besides, the reagents consumption is drastically reduced due to the injection of few tens of nanoliters. [less ▲]

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See detailSurvey for Ortho-to-Para Abundance Ratios (OPRs) of NH2 in Comets: Revisit to the Meaning of OPRs of Cometary Volatiles
Kawakita, Hideyo; Shinnaka, Yoshiharu; Jehin, Emmanuel ULg et al

in Bulletin of the American Astronomical Society (2016, October 01), 48

Since molecules having identical protons can be classified into nuclear-spin isomers (e.g., ortho-H[SUB]2[/SUB]O and para-H[SUB]2[/SUB]O for water) and their inter-conversions by radiative and non ... [more ▼]

Since molecules having identical protons can be classified into nuclear-spin isomers (e.g., ortho-H[SUB]2[/SUB]O and para-H[SUB]2[/SUB]O for water) and their inter-conversions by radiative and non-destructive collisional processes are believed to be very slow, the ortho-to-para abundance ratios (OPRs) of cometary volatiles such as H[SUB]2[/SUB]O, NH[SUB]3[/SUB] and CH[SUB]4[/SUB] in coma have been considered as primordial characters of cometary molecules [1]. Those ratios are usually interpreted as nuclear-spin temperatures although the real meaning of OPRs is in strong debate. Recent progress in laboratory studies about nuclear-spin conversion in gas- and solid-phases [2,3] revealed short-time nuclear-spin conversions for water, and we have to reconsider the interpretation for observed OPRs of cometary volatiles. We have already performed the survey for OPRs of NH[SUB]2[/SUB] in more than 20 comets by large aperture telescopes with high-resolution spectrographs (UVES/VLT, HDS/Subaru, etc.) in the optical wavelength region [4]. The observed OPRs of ammonia estimated from OPRs of NH[SUB]2[/SUB], cluster around ~1.1 (cf. 1.0 as a high-temperature limit), indicative of ~30 K as nuclear-spin temperatures. We present our latest results for OPRs of cometary NH[SUB]2[/SUB] and discuss about the real meaning of OPRs of cometary ammonia, in relation to OPRs of water in cometary coma. Chemical processes in the inner coma may play an important role to achieve un-equilibrated OPRs of cometary volatiles in coma.This work was financially supported by MEXT Supported Program for the Strategic Research Foundation at Private Universities, 2014–2018 (No. S1411028) (HK) and by Graint-in-Aid for JSPS Fellows, 15J10864 (YS).References:[1] Mumma & Charnley, 2011, Annu. Rev. Astro. Astrophys. 49, 471.[2] Hama & Watanabe, 2013, Chem. Rev. 113, 8783.[3] Hama et al., 2008, Science 351, 6268.[4] Shinnaka et al., 2011, ApJ 729, 81. [less ▲]

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See detailQuality Control Laboratories involved in the WHO Prequalification
Marini Djang'Eing'A, Roland ULg

Conference (2016, October)

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See detailComportement clinique des couronnes monolithiques en zircone
KOENIG, Vinciane ULg; Wulfman, Claudine; MAINJOT, Amélie ULg

in Les entretiens d'Odontologie-Stomatologie 2016 (2016, October)

Les études cliniques sur les couronnes et les bridges en zircone Y-TZP ont indiqué des taux d'échecs élevés liés aux fractures cohésives de la céramique d’émaillage (chipping). Pour remédier à ce problème ... [more ▼]

Les études cliniques sur les couronnes et les bridges en zircone Y-TZP ont indiqué des taux d'échecs élevés liés aux fractures cohésives de la céramique d’émaillage (chipping). Pour remédier à ce problème, les fabricants commercialisent des couronnes monolithiques, entièrement en zircone, qui sont simplement maquillées en surface. Cependant, ces restaurations sont suspectées d’être plus sensibles à la fatigue hydrique de la zircone, problème qui aboutit à une baisse des propriétés mécaniques et qui fut à l’origine de nombreux échecs avec les prothèses de hanche. En effet, l’absence de céramique d’émaillage sur les couronnes monolithiques les rend plus vulnérables vis à vis du milieu oral ; de plus, certaines zircones de haute translucidité, spécifiquement développées pour cette indication, sont réputées plus sensibles en raison d’une plus grande métastabilité. Enfin, le recul clinique sur ces restaurations est très faible et leur comportement général, notamment en terme d’usure des dents antagonistes, a besoin d’être étudié. Une étude clinique est actuellement menée à l’Université de Liège, en collaboration avec l’Université Paris Descartes, afin d’évaluer le comportement clinique de la zircone non émaillée en milieu buccal, et particulièrement la fatigue hydrique, sur une période de 5 ans. Les résultats à très court terme (6 mois) mettent en évidence le bon comportement clinique des restaurations monolithiques en zircone, avec cependant une usure rapide de la glaçure, ce qui pourrait promouvoir la fatigue hydrique. Les zones de transformation cristalline détectées soulignent la nécessité d’une cuisson de régénération de la zircone suite aux ajustements occlusaux par fraisage. [less ▲]

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See detailThe smallholder development by remittances of migrants
Yao Namé, Juste Michel ULg; Lebailly, Philippe ULg

in African Association of Agricultural Economists (AAAE)/AgEconsearch (2016, October)

The following pages report the results of our survey conducted among (Malian, Senegalese and Mauritanian) Soninké migrants during the period of 14th to 4 December 2015, living in the social residences of ... [more ▼]

The following pages report the results of our survey conducted among (Malian, Senegalese and Mauritanian) Soninké migrants during the period of 14th to 4 December 2015, living in the social residences of the former home Pinel (first home of migrant workers in France). This survey had to aim to discuss the implementation and use of a new tool to transfer the money in order to reduce use of informal channels, to promote financial inclusion, to finance smallholding and to develop entrepreneurship in rural by granting of credits medium or long term via Microfinance Institutions (IMF). [less ▲]

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See detailClassification criteria for neurogenic claudication caused by lumbar spinal stenosis
Genevay, Stéphane; Courvoisier, Delphine; Konstantinou, Kika et al

in 9th Interdisciplinary World Congress on Low Back And Pelvic Girdle Pain (2016, October)

BACKGROUND Classification criteria are recommended for diseases that lack highly specific biomarkers in order to improve homogeneity in clinical research. Since imaging evidence of lumbar spinal stenosis ... [more ▼]

BACKGROUND Classification criteria are recommended for diseases that lack highly specific biomarkers in order to improve homogeneity in clinical research. Since imaging evidence of lumbar spinal stenosis (LSS) or lumbar disc herniations (LDH) may not be associated with symptoms, clinical classification criteria based upon patient symptoms and physical examination findings are required. This study sought to develop a set of criteria identifying patients with neurogenic claudication (NC) caused by LSS and patient with radicular pain (RP) caused by LDH. This abstract reports the results concerning NC caused by LSS. METHODS Phase 1: Nineteen spine specialists (clinicians and researchers) from 8 countries participated in a Delphi process, using an internet program, to rank symptoms and signs which suggest LSS as the cause of NC or DH as the cause of RP. Phase 2: Nineteen different spine specialists (surgeons and non-surgeons) from 5 countries recruited patients during office visits and classify them with a high degree of confidence as having with either: 1) NC caused by LSS 2) RP caused by LDH or 3) non-specific low back pain (NSLBP) with non-specific leg pain radiation. Patients completed survey items and specialists documented examination signs. Signs and symptoms present in ≥ 10 patients were analyzed by using Generalized Estimating Equations (GEE). Patients with NC caused by LSS or NSLBP served as controls. Items with p<0.1 in univariate analysis were entered in the multivariate analysis. A score to predict NC caused by LSS was developed based on the coefficient of the GEE, and used to obtain a ROC curve and the associated area under the curve (AUC). RESULTS A list of 46 clinical signs and 28 patient-reported symptoms were selected by the group of spine specialists during the 1st phase. For the 2nd phase, 209 patients with high confidence in the diagnosis were included 63 NC caused by LSS, 89 RP caused by DH, and 57 NSLBP with non-specific leg pain radiation. Items which predicted NC with a p-value <0.1 included age >60, bilateral leg pain, leg pain relieved by sitting, leg pain decreased by leaning or flexing, positive30 seconds extension test, negative straight leg raise test. The score had an AUC of 0.91, and the cutoff to obtain a specificity of 92.1% resulted in a sensitivity of 80.0%. CONCLUSION An international collaboration of surgeon and non-surgeon spine specialists produced a set of diagnostic criteria with high specificity and sensitivity for identifying patients with NC caused by LSS. Using this set could improve the quality of basic science and clinical research in this field by improving homogeneity within groups of patients. [less ▲]

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See detailThyroid nodule : metastasis or primary neoplasm ?
PETIGNOT, Sandrine ULg; PETROSSIANS, Patrick ULg; VAN DAELE, Daniel ULg et al

in 26nd meeting of the Belgian Endocrine Society - Abstract book (2016, October)

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See detailUtilisation de la cabergoline dans le traitement palliatif de la maladie de Cushing : l'étude Frenchcab
Ferriere, A; Cortet, C; Chanson, P et al

in Annales d'Endocrinologie : 33ème congrès de la Société Française d'Endocrinologie (2016, October)

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See detailA membrane-type- matrix metalloproteinase (MT1-MMP) - discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells
Assent, Delphine; Bourgot, Isabelle ULg; Hennuy, Benoit et al

Poster (2016, October)

During tumour dissemination, invading breast carcinoma cells become confronted with a reactive stroma, a type I collagen-rich environment endowed with anti-proliferative and proapoptotic properties. To ... [more ▼]

During tumour dissemination, invading breast carcinoma cells become confronted with a reactive stroma, a type I collagen-rich environment endowed with anti-proliferative and proapoptotic properties. To develop metastatic capabilities, tumour cells must acquire the capacity to cope with this novel microenvironment. How cells interact with and respond to their microenvironment during cancer dissemination remains poorly understood. To address the impact of type I collagen on the fate of tumour cells, human breast carcinoma MCF-7 cells were cultured within three-dimensional type I collagen gels (3D COL1). Using this experimental model, we demonstrate that membrane type-1 matrix metalloproteinase (MT1-MMP), a proteinase overexpressed in many aggressive tumours, promotes tumour progression by circumventing the collagen-induced up-regulation of BIK, a pro-apoptotic tumour suppressor, and hence apoptosis. A transcriptomic analysis was performed to decipher the molecular mechanisms regulating 3D COL1-induced apoptosis in human breast cancer cells. Control and MT1-MMP expressing MCF-7 cells were cultured on two-dimensional plastic plates or within 3D COL1 and a global transcriptional time-course analysis was performed. Shifting the cells from plastic plates to 3D COL1 activated a complex reprogramming of genes implicated in various biological processes. Bioinformatic analysis revealed a 3D COL1-mediated alteration of key cellular functions including apoptosis, cell proliferation, RNA processing and cytoskeleton remodelling. By using a panel of pharmacological inhibitors, we identified discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase specifically activated by collagen, as the initiator of 3D COL1-induced apoptosis. Our data support the concept that MT1-MMP contributes to the inactivation of the DDR1-BIK signalling axis through the cleavage of collagen fibres and/or the alteration of DDR1 receptor signalling unit, without triggering drastic alterations of the transcriptome of MCF-7 cells. [less ▲]

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See detailLes dernières évolutions en droit européen en matière d'assurance protection juridique
Wildemeersch, Jonathan ULg

in Wildemeersch, Jonathan (Ed.) L'assurance protection juridique : quid pour demain? (2016, October)

L'assurance protection juridique est régie par une directive européenne. Comment la Cour de justice interprète-t-elle le principe du libre choix de l'avocat imposé par la directive ? Tel est l'objet de ... [more ▼]

L'assurance protection juridique est régie par une directive européenne. Comment la Cour de justice interprète-t-elle le principe du libre choix de l'avocat imposé par la directive ? Tel est l'objet de cette contribution. [less ▲]

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See detailFrom guidelines to real daily practice : prolactinoma in pregnancy
VROONEN, Laurent ULg; Potorac, Iulia ULg; D'Andréa, S et al

in Annales d'Endocrinologie : 33ème congrès de la Société Française d'Endocrinologie (2016, October)

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See detailLes corps des scientifiques et de l’intellectuel dans la revue La Recherche
Dondero, Maria Giulia ULg

in Mabrour, Abdel; Bajomée, Danielle (Eds.) La lettre et l’image. Enquêtes interculturelles sur les territoires du visible (2016, October)

Ce travail entend examiner les rapports entre les représentations photographiques des corps des scientifiques dans la revue de vulgarisation savante La Recherche, tels les portraits, les scènes de travail ... [more ▼]

Ce travail entend examiner les rapports entre les représentations photographiques des corps des scientifiques dans la revue de vulgarisation savante La Recherche, tels les portraits, les scènes de travail collectif en laboratoire etc., et les conceptions de la science qui en sont valorisées. L’étude des relations entre les photographies et les textes qui les accompagnent ont ainsi pour objectif de déployer une réflexion non seulement sur les différents types de commensurabilité entre le langage verbal et le langage visuel mais aussi sur le fait que le langage visuel est à même de forger de manière tout à fait autonome des valeurs identitaires et des formes de vie identifiables via l’analyse sémiotique. Notre exploration se développera en deux volets : le premier vise à esquisser la méthodologie de la sémiotique visuelle pour pouvoir introduire les niveaux pertinents de l’analyse sémiotique, le deuxième consiste à analyser un corpus constitué de textes tirés de quelques numéros de la revue La Recherche en en distinguant les différents genres discursifs (entretien, présentation de travaux en cours, etc.) et les différents types de cadrage et de mise en scène photographique afin d’expliquer comment ils se combinent avec les prises de position épistémologiques valorisées. [less ▲]

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See detailHypogonadism due to a novel inactivating mutation of the luteinizing hormone beta subunit (LHB) gene leading to impaired protein trafficking
Potorac, Iulia ULg; Rivero-muller, a; Trehan, A et al

in 26nd meeting of the Belgian Endocrine Society - Abstract book (2016, October)

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See detailADAM28 - Generation of a conditional ADAM28 knock-out mouse Implication of ADAM28 in metastasis dissemination
Gérard, Catherine ULg; Rocks, Natacha ULg; Carnet, Oriane ULg et al

Poster (2016, October)

Introduction: ADAMs (a disintegrin and metalloproteinase) and ADAMTS proteinases (a disintegrin and metalloproteinase with thrombospondin motifs) are MMP (matrix metalloproteinase) -related enzymes ... [more ▼]

Introduction: ADAMs (a disintegrin and metalloproteinase) and ADAMTS proteinases (a disintegrin and metalloproteinase with thrombospondin motifs) are MMP (matrix metalloproteinase) -related enzymes, bearing a multi-domain structure. ADAM28 is a multipotent membrane-bound proteinase and its expression in tissues derived from the foregut in embryonic tissues suggests its involvement in the organogenesis of the respiratory tract. Moreover, ADAM28 is highly overexpressed in non-small-cell lung cancer samples. Notably through a global proteomic approach, we recently identified an upregulation of ADAM28 after induction of lung inflammation in a mouse model of asthma. In addition to data published in the literature and to our findings about ADAM28 expression in various pathological tissues, intrinsic characteristics of this proteinase argue for considering it as a potential regulator of cellular signalling pathways leading to an inflammatory pulmonary microenvironment and, eventually, to carcinogenesis. Indeed, ADAM28 bears an active catalytic domain and interacts in a non-proteolytic manner with some integrins (α4β1) and some P-selectin ligands involved in inflammatory cell migration. ADAM28 was also reported to display the capacity to cleave key mediators such as Von Willebrand factor, IGFBP3 (Insulin-like growth factor-binding protein 3) and CTGF (Connective Tissue Growth Factor). Very recently, ADAM28 was shown to shed pro-TNF-alpha suggesting an important role in tumour control. The present project aims at characterizing molecular mechanisms leading to tumour development in lungs. In the first part of this work, we intend to characterize the effects of ADAM28 depletion on physiological and pathological processes such as tumor development and metastatic dissemination in ADAM28 conditional knock-out mice. Methods: To understand the implication of ADAM28 in lung tumour development we instillated lungs of mice displaying a full knock-out genotype for ADAM28 with Lewis Lung Carcinoma cells and B16K1 melanoma cells. ADAM28 KO mice were also injected intravenously and a subcutaneously with these tumour cells. Results: There is no spontaneous phenotype for ADAM28 full knock-out animals. Preliminary results show an impaired lung tumors engrafment in ADAM28 wild type animals when compared to heterozygous or knock out littermates. Conclusion: This unique mouse strain provides a very precious tool to further investigate ADAM28 implication in various disease models including tumour growth and dissemination. The role of ADAM28 as a pro-tumor factor is widely described in the literature whereas our results suggest that ADAM28 has an anti-tumor function. [less ▲]

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See detailUsing images to analyze images. Semiotics meets Cultural Analytics
Dondero, Maria Giulia ULg

in Reyes-Garcia, Everardo; Châtel-Innocenti, Pierre; Zreik, Khaldoun (Eds.) Archiving and Questioning Immateriality - Proceedings of the 5th Computer Art Congress (2016, October)

In our text we examine image visualizations generated from big collections of archived images produced by Lev Manovich and his team in the field of Cultural Analytics. Our aim is to examine how these ... [more ▼]

In our text we examine image visualizations generated from big collections of archived images produced by Lev Manovich and his team in the field of Cultural Analytics. Our aim is to examine how these image visualizations function as analysis-images from two correlated perspectives of one semiotic approach: 1. Enunciation. What point of view is conveyed by the image visualizations about the computer-manipulated archive images? 2. Rhetorical/mereological composition: What is the mereological relation between the final visualization and the multitude of images that it contains, filters, or manipulates? [less ▲]

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See detailThe peroxisome proliferator-activated receptor Alpha (PPARA) is expressed in non-somatotroph pituitary adenomas : a potential therapeutic target ?
Rotondi, S; Polidoro, MA; Morace, R et al

Poster (2016, October)

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See detailInvestigating the potential of Cymodocea nodosa (Ucria) Ascherson as a coastal carbon sink coupling marine habitat cartographies and in situ nondestructive sampling
Abadie, Arnaud ULg; Richir, Jonathan ULg; Pieraccini, Riccardo ULg et al

Poster (2016, October)

Seagrass meadows are major carbon sinks, trapping about 10% of the total CO2 sequestrated in the oceans. In the Mediterranean, a major focus has been made on the climax species Posidonia oceanica (L ... [more ▼]

Seagrass meadows are major carbon sinks, trapping about 10% of the total CO2 sequestrated in the oceans. In the Mediterranean, a major focus has been made on the climax species Posidonia oceanica (L.) Delile, while other species remained little studied. In the framework of the STARECAPMED project, we thus chose to study Cymodocea nodosa (Ucria) Ascherson, a pioneer species with a rapid turnover and an expected high stocking capacity. Furthermore, the area covered by that species has been largely underestimated. In order to fill these two knowledge gaps, we first mapped all seagrass habitats within a Mediterranean bay (Calvi, Corsica, France) using side scan images, aerial photographs and ground truths. This cartography was followed by seasonal in situ density measurements and non-destructive shoot sampling (leaf cutting). Samplings were performed at different depths (5 to 23 m depth) in 6 contrasted stations (small patchy meadows to continuous beds) in order to cover all the existing facies of the bay. Elementary contents (carbon, nitrogen and stable isotope ratios) were measured in laboratory. This first work shows that C. nodosa meadows in Calvi Bay cover an area of 0.498 km2. Carbon stocks of the leaves reached 0.25 tons in winter and 2.72 tons in summer. Their nitrogen contents showed a marked seasonality with a maximum value of 0.020 mgN.m-2 in July and a minimum value of 0.005 mgN.m-2 in March. Some modifications in the trophic conditions of the water column at several stations were put in an obvious through the N stable isotopes values, mostly during the summer period. The actual underestimation of the area covered by that species in Calvi Bay has been properly mapped thanks to side scan sonar techniques revealing, together with elementary content analysis, its importance in the carbon balance of coastal areas. [less ▲]

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See detailClassification Criteria for Neurogenic Claudication Caused by Lumbar Spinal Stenosis
Genevay, Stéphane; Courvoisier, Delphine; Konstantinou, Kika et al

in EuroSpine 2016 (2016, October)

BACKGROUND Classification criteria are recommended for diseases that lack highly specific biomarkers in order to improve homogeneity in clinical research. Since imaging evidence of lumbar spinal stenosis ... [more ▼]

BACKGROUND Classification criteria are recommended for diseases that lack highly specific biomarkers in order to improve homogeneity in clinical research. Since imaging evidence of lumbar spinal stenosis (LSS) or lumbar disc herniations (LDH) may not be associated with symptoms, clinical classification criteria based upon patient symptoms and physical examination findings are required. This study sought to develop a set of criteria identifying patients with neurogenic claudication (NC) caused by LSS and patient with radicular pain (RP) caused by LDH. This abstract reports the results concerning NC caused by LSS. METHODS Phase 1: Nineteen spine specialists (clinicians and researchers) from 8 countries participated in a Delphi process, using an internet program, to rank symptoms and signs which suggest LSS as the cause of NC or DH as the cause of RP. Phase 2: Nineteen different spine specialists (surgeons and non-surgeons) from 5 countries recruited patients during office visits and classify them with a high degree of confidence as having with either: 1) NC caused by LSS 2) RP caused by LDH or 3) non-specific low back pain (NSLBP) with non-specific leg pain radiation. Patients completed survey items and specialists documented examination signs. Signs and symptoms present in ≥ 10 patients were analyzed by using Generalized Estimating Equations (GEE). Patients with NC caused by LSS or NSLBP served as controls. Items with p<0.1 in univariate analysis were entered in the multivariate analysis. A score to predict NC caused by LSS was developed based on the coefficient of the GEE, and used to obtain a ROC curve and the associated area under the curve (AUC). RESULTS A list of 46 clinical signs and 28 patient-reported symptoms were selected by the group of spine specialists during the 1st phase. For the 2nd phase, 209 patients with high confidence in the diagnosis were included 63 NC caused by LSS, 89 RP caused by DH, and 57 NSLBP with non-specific leg pain radiation. Items which predicted NC with a p-value <0.1 included age >60, bilateral leg pain, leg pain relieved by sitting, leg pain decreased by leaning or flexing, positive30 seconds extension test, negative straight leg raise test. The score had an AUC of 0.91, and the cutoff to obtain a specificity of 92.1% resulted in a sensitivity of 80.0%. CONCLUSION An international collaboration of surgeon and non-surgeon spine specialists produced a set of diagnostic criteria with high specificity and sensitivity for identifying patients with NC caused by LSS. Using this set could improve the quality of basic science and clinical research in this field by improving homogeneity within groups of patients. [less ▲]

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See detailPotential for Composite Analysis in the Black Sea
Capet, Arthur ULg; Mason, Evan; Troupin, Charles et al

Conference (2016, October)

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See detailSomatic mosaicism is implicated in the etiology of XLAG syndrome
Rostomyan, Liliya ULg; Daly, Adrian ULg; Yuan, Bo et al

in 26nd meeting of the Belgian Endocrine Society - Abstract book (2016, October)

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See detailRegulation of breast carcinoma cell proliferation and apoptosis by type I collagen aging and 3D confinement involves differential activation of DDR1
Saby, Charles; Rammal, Hassan; Magnien, Kevin et al

Poster (2016, October)

During breast carcinoma development, cells are confronted to a type I collagen-rich environment which induces anti-proliferative and pro-apoptotic effects (Maquoi et al., Oncogene, 2012). These effects ... [more ▼]

During breast carcinoma development, cells are confronted to a type I collagen-rich environment which induces anti-proliferative and pro-apoptotic effects (Maquoi et al., Oncogene, 2012). These effects occurred only in 3D cell matrix and involved Discoidin Domain Receptor 1 (DDR1) but not β1 integrin (Assent et al., PlosOne, 2015). During aging, type I collagen undergoes post-translational modifications which have a detrimental effect on type I collagen fibrillar organization (Aït-Belkacem, J Biomed Optics, 2012 ; Guilbert et al., Oncotarget, 2016). This property is well known to be requested to activate DDR1. Here, we address the effect of type I collagen aging on cell proliferation inhibition and apoptosis induction in breast carcinoma cells in 3D cell confinement system. Type I collagen was extracted from tail tendons of 2 months (adult) and 2 years (old) rats, and MCF-7 and ZR-75-1 cells were used as an experimental model. We provide evidence for a decrease in cell proliferation by adult collagen but not by old one. This effect involves a higher phosphorylation of DDR1 by adult collagen when compared to the old one. Inhibition of DDR1 kinase activity by the specific inhibitor DDR1-IN-1 induced an increase in cell proliferation to a level similar to that observed in old collagen. An increase in cell proliferation was also observed using siRNA targeting DDR1 mRNA. At the opposite of old collagen, adult collagen was also able to trigger apoptosis by inducing an increase in expression of the pro-apoptotic protein (BIK). Inhibition of DDR1 kinase activity induced a decrease in BIK expression and apoptosis. Our data support the concept that aging contributes to the loss of the growth suppression and apoptotic effect of collagen on breast carcinoma, but only in 3D cell confinement model, by inactivating the DDR1-BIK signaling axis via a downregulation of DDR1 activation. [less ▲]

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See detailMultimodal Connectivity-Based Parcellation of the Brain
Reuter, Niels; Plachti, Anna; Genon, Sarah ULg et al

Poster (2016, October)

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See detailFaut-il suivre par IRM hypophysaire les patients porteurs de macroprolactinome dont l'hypersécrétion est contrôlée médicalement ?
Eroukhmanoff, J; Tejedor, I; Potorac, Iulia ULg et al

in Annales d'Endocrinologie : 33ème congrès de la Société Française d'Endocrinologie (2016, October)

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See detailA new clinical presentation of a non-so-rare disease, the Di George syndrome
VROONEN, Laurent ULg; D'Andrea, S; Tome, M et al

in Annales d'Endocrinologie : 33ème congrès de la Société Française d'Endocrinologie (2016, October)

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See detailLe droit public et le tiers. Rapport belge
Bouhon, Frédéric ULg

in Les tiers. Journées panaméennes (2016, October)

Le présent rapport envisage le rôle du tiers en droit public belge, en se focalisant sur les trois thématiques retenues par le rapporteur général : le tiers et la norme (I), l’intérêt du tiers (II) et ... [more ▼]

Le présent rapport envisage le rôle du tiers en droit public belge, en se focalisant sur les trois thématiques retenues par le rapporteur général : le tiers et la norme (I), l’intérêt du tiers (II) et l’exécution de tâches publiques et le tiers (III). [less ▲]

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See detailA Simple Method for Thermal Characterization of Low-Melting Temperature Phase Change Materials (PCMs)
Salvador, Lucas ULg; Hastanin, Juriy ULg; Novello, Frédéric et al

in COMSOL 2016 Proceedings (2016, October)

The successful implementation of a high-efficient latent heat storage system necessitates an appropriate experimental approach to investigate and quantify the variations of the Phase Change Material (PCM ... [more ▼]

The successful implementation of a high-efficient latent heat storage system necessitates an appropriate experimental approach to investigate and quantify the variations of the Phase Change Material (PCM) thermal properties caused by its aging, as well as its potential demixing induced by cyclic freezing and melting. In this paper, we present a concept for the PCM characterization. The proposed method is relatively simple to be implemented. It consists of a cyclic cooling and melting of the PCM sample placed into a tube and monitoring its temperature evolution with a set of temperature sensors. In our work, the temperature evolution of the sample, as well as its sensitivity to the thermal parameters have been numerically investigated using the COMSOL Multiphysics® software. [less ▲]

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See detailUn chantier de modernisation des contextes de travail: le "New Way of Working" dans une compagnie d'assurances
Jemine, Grégory ULg

Conference (2016, October)

Dans les réflexions récentes portant sur l’organisation du travail en entreprise, nombreux sont les auteurs qui s’intéressent à la question des « nouvelles formes d’organisation ». Sous cette appellation ... [more ▼]

Dans les réflexions récentes portant sur l’organisation du travail en entreprise, nombreux sont les auteurs qui s’intéressent à la question des « nouvelles formes d’organisation ». Sous cette appellation se rassemblent des courants aux dénominations différentes (entreprise libérée, entreprise virtuelle, « holacracie »…) partageant cependant des principes fondateurs communs (tels que la flexibilité, l’autonomie du collaborateur ou encore la digitalisation des pratiques de travail). A travers une étude de trois mois au sein d’un département de protection juridique d’une importante compagnie d’assurances située à Bruxelles, nous étudions un projet de changement basé sur le « New Way of Working » (NWoW) – un chantier managérial se développant principalement aux Pays-Bas et en Belgique depuis une dizaine d’années, proposant une « nouvelle » vision des travailleurs dans le secteur tertiaire. Nous rendons compte des trois composantes clés du projet NWoW telles qu'il est problématisé dans notre étude de cas: les Bricks (travail en open-space, bureaux flexibles, travail à distance), les Bytes (nouveaux outils numériques, travail sans papier, connectivité) et les Behaviors (autonomie et responsabilité des collaborateurs, passage du contrôle à la confiance). Nous concluons par une réflexion structurée autour des "4C": dans ces nouveaux environnements de travail, de nouvelles questions émergent en termes de confiance, de contrôle, de cohésion et de coordination. [less ▲]

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See detailUsing PCB signatures and enantiomer fractions for source identification and to age date exposure
Megson, D; Focant, Jean-François ULg; Patterson, D et al

Conference (2016, October)

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See detailGestion du stress professionnel : sensibilisation aux processus psychologiques et outils de gestion dérivés
Brouette, Béatrice ULg; Stassart, Céline ULg; Dethier, Marie ULg et al

in Etienne, Anne-Marie; Bragard, Isabelle (Eds.) Evolutions sociales, Innovations et Politiques: nouvelles questions et nouveaux enjeux pour la psychologie de la santé. (2016, October)

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See detailA review of Silurian dispersed spore assemblages from the Arabian Plate: biostratigraphy and palaeogeography
Wellman, CH; Steemans, Philippe ULg; Breuer, P et al

Conference (2016, October)

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See detailAgent-based analysis of dynamic access ranges to the distribution network
Mathieu, Sébastien ULg; Ernst, Damien ULg; Cornélusse, Bertrand ULg

in Proceedings of the 6th European Innovative Smart Grid Technologies (ISGT) (2016, October)

There is a need to clearly state an interaction model that formalizes interactions between actors of the distribution system exchanging flexibility. In previous works we quantitatively evaluated the ... [more ▼]

There is a need to clearly state an interaction model that formalizes interactions between actors of the distribution system exchanging flexibility. In previous works we quantitatively evaluated the performance of five interaction models devised with industrial partners using the agent-based testbed DSIMA. Simulation results showed that these interaction models relying on active network management suffer from a lack of coordination between the distribution and the transmission system operator, activating flexibility simultaneously in opposite directions. This paper introduces a new interaction model fixing this issue based on dynamic access bounds to the network changing throughout the day and preventing the activation of flexibility leading to congestions. This new interaction model is implemented in DSIMA and compared to a model restricting the grid users to a very restrictive but safe access range. Results show that this new model allows to safely increase by 55% the amount of distributed generation in the network. [less ▲]

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See detailRobust discriminant analysis based on the joint graphcial lasso estimator
Aerts, Stéphanie ULg; Croux, Christophe; Wilms, Ines

Poster (2016, October)

Linear and Quadratic Discriminant Analysis (LDA/QDA) are the most often applied classification rules under the normality assumption. When there is not enough data, the quadratic rule, which requires the ... [more ▼]

Linear and Quadratic Discriminant Analysis (LDA/QDA) are the most often applied classification rules under the normality assumption. When there is not enough data, the quadratic rule, which requires the estimation of one precision matrix in each class, is often replaced by the linear one, based on the homoscedasticity assumption. This strong assumption is however rarely verified in practice and ignores the intrinsic différences between groups that may be of particular interest in the classification context. In this aper, alternatives to the usual maximum likelihood estimates for the precision matrices are proposed that borrow strength across classes while allowing for heterogeneity at the same time. This results in a classifier that is intermediate between QDA and LDA. Moreover, our estimator is sparse: the undesirable effect of uninformative variables is reduced. The performance of the method is illustrated through simulated and real dataset examples. [less ▲]

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See detailStudy of the SV2A protein role in Epilepsy.
Bartholomé, Odile ULg; Van Den Ackerveken, Priscilla ULg; Wislet, Sabine ULg et al

Poster (2016, October)

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See detailMise en oeuvre de l'intermédialité dans l'élaboration d'un théâtre politique
Delhalle, Nancy ULg

Conference (2016, October)

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See detailLRP4 mutations in bilateral renal agenesis with severe limb deficiencies
JACQUINET, Adeline ULg; LEE, Anna F.; SWENERTON, Anna et al

Poster (2016, October)

Introduction : Severe limb deficiencies have been reported in association with bilateral renal agenesis in several syndromes. Recently, truncating mutations in LRP4 have been associated with a lethal ... [more ▼]

Introduction : Severe limb deficiencies have been reported in association with bilateral renal agenesis in several syndromes. Recently, truncating mutations in LRP4 have been associated with a lethal autosomal recessive form of Cenani-Lenz syndrome (CLS). The objectives of our study was to delineate the phenotype of the third fetus, and through a search of syndromes, identify a group of disorders with overlapping phenotypes that may be allelic with CLS or due to mutations in the same pathway. Results : A male fetus at 22 weeks’ gestation was found to have bilateral renal agenesis by ultrasound. The pregnancy was interrupted and autopsy and skeletal survey revealed shortening of forearms and legs below the knees, radioulnar synostosis, foreshortened triangular shaped tibia and fibula, and oligosyndactyly with disorganized metacarpals, metatarsals and phalanges. Bilateral renal agenesis, absent ureters and small bladder were confirmed. Additional features included downslanting palpebral fissures, high-arched palate, small mouth, low-set and posteriorly rotated ears, nuchal oedema, pulmonary hypoplasia, hypospadias and absent olfactory nerves. An autosomal recessive disorder was suspected, given a prior obstetric history of termination at 18 weeks for unilateral limb anomalies and cleft lip. Based on the aforementioned renal and limb anomalies, the lethal form of CLS was considered. Sequencing of LRP4 identified a paternally inherited variant (c.919+3G del) and a maternally inherited variant (c.4808T>A ;p.Ile1603Val). Both variants were rare in the general population and bioinformatically predicted to be damaging. We compared the phenotype with the two previously reported fetuses as well as with syndromes and disorders that may present prenatally with genitourinary anomalies plus acromesomelia of upper and lower limbs. We found significant overlap with a subset of cases of acro-renal-uterine-mandibular syndrome presenting with high-arched palate plus or minus micrognathia and microglossia, severe limb anomalies affecting the middle and distal segments, oligosyndactyly, renal agenesis, uterine anomalies and absence of olfactory nerves. Conclusion : Based on the clinical features seen in three lethal cases of CLS, we propose that acro-renal-uterine-mandibular syndrome may be allelic with CLS or due to mutations in the molecular pathway involving LRP4. [less ▲]

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See detailOceanBrowser: on-line visualization of gridded ocean data and in situ observations
Barth, Alexander ULg; Watelet, Sylvain ULg; Troupin, Charles et al

Conference (2016, October)

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See detailHistorical Mortars in Wallonia (Belgium): A New Archaeological Approach. The Case of the Mediaeval Fortress of Pont-de-Bonne (Belgium, Province of Liège)
Demelenne, Marie; Bossiroy, Dominique; Dagrain, Fabrice et al

in Papayianni, Ioanna; Stefanidou, Maria; Pachta, Vasiliki (Eds.) 4th Historic Mortars Conference HMC2016 (2016, October)

This paper deals with an innovative methodology dedicated to the study of historical mortars. Gathering macroscopic observation, petrography in thin sections, chemical analyses as well as physical and ... [more ▼]

This paper deals with an innovative methodology dedicated to the study of historical mortars. Gathering macroscopic observation, petrography in thin sections, chemical analyses as well as physical and mechanical data namely obtained with non destructive technologies developed for the petroleum industry, it allows cross-interpretation that can effectively contribute to archaeological research through correlations with the age, the function, the technology and the provenance of each mortar sample collected on a studied site. Following a synthetic description of the proposed approach, a practical application is illustrated on the site of a mediaeval fortress located in Belgium. [less ▲]

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See detailPrésentation de l'Atlas national de Belgique - versions 1 à 3 et version numérique
Van Hecke, Etienne; Binard, Marc ULg; Donnay, Jean-Paul ULg

Conference (2016, September 30)

This presentation is divided into 3 parts: The "paper" version of the National Atlas, from the first to the third edition. The digital version of the National Atlas. A presentation of Geomatics Unit of ... [more ▼]

This presentation is divided into 3 parts: The "paper" version of the National Atlas, from the first to the third edition. The digital version of the National Atlas. A presentation of Geomatics Unit of the University of Liege, and its role in the realization of the 3rd edition of the National Atlas and its digital version. [less ▲]

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See detailDesign of an experimental set-up to analyse compliant mechanisms used for the deployment of a panel
Dewalque, Florence ULg; Bruls, Olivier ULg

in Proceedings of the 14th European Conference on Spacecraft Structures, Materials and Environmental Testing (ECSSMET) (2016, September 30)

Due to their high complexity, compliant mechanisms require high-fidelity mechanical models to reach a detailed understanding of their characteristics and predict their actual behaviour in various ... [more ▼]

Due to their high complexity, compliant mechanisms require high-fidelity mechanical models to reach a detailed understanding of their characteristics and predict their actual behaviour in various situations. This work focuses on tape springs which are used as an alternative to common mechanisms composed of kinematic joints. They present several assets such as, among others, passive deployment and self-locking, but they are characterised by a highly nonlinear behaviour including buckling, the formation of folds and hysteresis. An experimental set-up is then designed to gather information on these phenomena, while in parallel an equivalent finite element model is developed. Quasi-static and dynamic tests are performed, as well as small amplitude vibration tests and large amplitude deployments in order to collect data in a broad variety of cases. The post-processing of the numerous raw data shows, with the help of statistical considerations, the good quality of the acquisitions. Finally, the finite element model proves to be fairly well correlated to the experimental results. [less ▲]

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See detailRésultats d'une enquête sur la diffusion des thèses en droit
Bouhon, Frédéric ULg

Conference (2016, September 30)

Cette interviention, destinée aux doctorants et aux jeunes docteurs en droit, visait à présenter les résultats d'une enquête menée par l'auteur sur la diffusion des thèses en droit. Il s'agissait de ... [more ▼]

Cette interviention, destinée aux doctorants et aux jeunes docteurs en droit, visait à présenter les résultats d'une enquête menée par l'auteur sur la diffusion des thèses en droit. Il s'agissait de présenter les tendances suivies par les docteurs récemment diplômés dans les facultés de droit de Belgique francophone. L'intervention a été suivie d'un débat avec le public ainsi qu'avec des éditeurs présents. [less ▲]

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See detailTransition to parenthood of lesbian parents: key processes and clinical implications
Scali, Thérèse ULg; D'Amore, Salvatore ULg; Haxhe, Stéphanie ULg et al

Conference (2016, September 29)

The transition to parenthood is a key process for understanding the development of family relationships in a systemic perspective. This process has been studied mostly in heterosexual families but very ... [more ▼]

The transition to parenthood is a key process for understanding the development of family relationships in a systemic perspective. This process has been studied mostly in heterosexual families but very few studies focus on families with same-sex families. This exploratory study analyzes the key passages of the transition from 17 lesbian headed families through a quantitative analysis of socio-demographic data, information about the coming-out, pair formation, project of the child, the child's arrival, as well as social and cultural pressures towards family and stressors. The main results show that the decision making to become parents is generally harmonious (70%) between the members of the couple, and only a few had substantial conflicts (17,1%). Moreover, the motivation to become parents seems to be stronger for the mother who carried the child (57, 1%)than for the social mother. The majority of the lesbian mothers reported no medical homophobia (64,3%) Regarding the caregiving tasks, they seem to be equally shared between social and biological mothers. In regards to the child, almost 70% are aware of their parents’ sexual orientation (as only 5.7% are not fully aware). Finally, no changes in the quality of relationship with the family of origin have been found after the birth of the baby. Clinical implications of these results will be discussed. [less ▲]

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See detailWho are the winners in the race against desiccation – phenotypic plasticity in a fossorial toad
Székely, Diana ULg; Székely, Paul; Denoël, Mathieu ULg et al

Conference (2016, September 29)

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See detailUsing a dynamic vegetation model for future projections of crop yields: simulations from the plot scale to the Belgian and European scales
Jacquemin, Ingrid ULg; Dury, Marie ULg; Henrot, Alexandra-Jane ULg et al

Conference (2016, September 29)

Dynamic vegetation models (DVM), such as CARAIB (“CARbon Assimilation In the Biosphere”) were initially designed to describe the dynamics of natural ecosystems as a function of climate and soil with the ... [more ▼]

Dynamic vegetation models (DVM), such as CARAIB (“CARbon Assimilation In the Biosphere”) were initially designed to describe the dynamics of natural ecosystems as a function of climate and soil with the aim of studying the role of vegetation in the carbon cycle. But their characteristics allow numerous other applications and improvements, such as the development of a crop module. This module can be validated at the plot scale, with the use of eddy-covariance data from agricultural sites in the FLUXNET network. The carbon fluxes (e.g., net ecosystem exchange (NEE), gross primary productivity (GPP)) and the evapotranspiration (ET) simulated with the CARAIB model are compared with the fluxes measured at several sites, in order to cover a maximum number of crop types (winter wheat/barley, sugar beets, potatoes, rapeseed,…) and to evaluate the model for different European regions (Belgium, France, Germany,…). The aim of this validation is to assess the model ability to reproduce the seasonal and inter-annual variability of carbon fluxes. In order to assess the spatial variability of the model, CARAIB will be applied over Belgium and forced with the outputs the regional climate model ALARO (4 km resolution), for the recent past and the decennial projections. To reach the larger scale, we also aim to assess crops yields over Europe and to quantify the uncertainties in the climatic projections. CARAIB will be driven with the outputs of different regional climatic models (RCMs), nested in CMIP5 GCM projections for the EURO-CORDEX project: ALADIN53 (Météo-France/CNRM), RACMO22E (KNMI), RCA4 (SMHI) and REMO2009 (MPI-CSC) RCMs. These climatic projections are at a high spatial resolution (0.11-degree, ≈12 km). The model will be set up for the most common crops in Europe and for simulations tests with marginal and/or new crops. Finally, this simulation ensemble will be used to highlight potential changes in the most productive areas of Europe. [less ▲]

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See detailProphéties, lyrisme et chevalerie. Portrait de Jacques Le Gros, bourgeois de Paris († 1551)
Lambert, Adélaïde ULg

Conference (2016, September 29)

Notre communication consistait à analyser les documents qui encadrent la fresque épique Gerard du Frattre dans le manuscrit unique Paris, BnF, fr. 12791, copié intégralement de la main de Jacques Le Gros ... [more ▼]

Notre communication consistait à analyser les documents qui encadrent la fresque épique Gerard du Frattre dans le manuscrit unique Paris, BnF, fr. 12791, copié intégralement de la main de Jacques Le Gros, un marchand de soie parisien. Outre la table des matières de Gerard du Frattre, ce corpus est notamment composé d’un inventaire de la bibliothèque de Jacques Le Gros, de prophéties portant sur des événements politiques contemporains (entre autres, sur les guerres opposant François Ier à Charles Quint), de pièces de vers amoureuses, satiriques ou pieuses, d’un placard affiché sur les portes de Notre-Dame, etc. Copiés entre 1525 et 1545 puis rassemblés dans un même codex, ces documents constituent un témoignage exceptionnel sur les intérêts d’un bourgeois de Paris et, plus largement, sur ceux du public des réécritures médiévales, durant la première moitié du XVIe siècle. En guise de prolongement, les résultats de notre enquête pourront alimenter la question de l’influence qu’a pu exercer le contexte politique et social du début du siècle sur la refonte des légendes médiévales : les pièces qui accompagnent Gerard du Frattre peuvent-elles être considérées comme des éléments paratextuels susceptibles d’orienter l’interprétation de la fiction placée au centre du manuscrit ? [less ▲]

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See detailPerformance et circuit de commercialisation des principaux produits agricoles des cuvettes oasiennes du département de Gouré
Malam Boukar, Awa Krou; Yahaya, Abdou; Yamba, Boubacar et al

Conference (2016, September 28)

Les cuvettes oasiennes du département de Gouré sont sources de production alimentaire et de revenus pour les populations locales. Elles jouent un rôle important dans la lutte contre l’insécurité ... [more ▼]

Les cuvettes oasiennes du département de Gouré sont sources de production alimentaire et de revenus pour les populations locales. Elles jouent un rôle important dans la lutte contre l’insécurité alimentaire et la pauvreté. L’objectif de cet article est de démontrer l’efficacité économique des principaux produits agricoles de cuvettes ainsi que les plateformes de commercialisation. Pour ce faire, trois démarches méthodologiques complémentaires ont été adoptées. La première permet d’identifier les produits agricoles les plus rentables selon le point de vu des producteurs, la seconde permet déterminer les principaux produits agricoles de cuvettes à travers le « test de Kendall » et la troisième permet de calculer la rentabilité économique des produits à travers des indicateurs de performance. Pour cela, neuf cuvettes ont été choisies suivant le niveau de nappe phréatique et le type de valorisation. Les enquêtes réalisées et les constats effectués montrent que toutes les spéculations sont rentables, puisque leur RPN dépasse les 50%. Les producteurs indiquent que le manioc est la spéculation la plus importante du fait de sa mise en culture, de sa consommation et de sa conservation facile. Les deux autres tests montrent les cultures à cycle court comme le chou (75%) et l’oignon (69%) sont plus attrayants. Il est aussi ressorti que les produits agricoles de cuvettes sont plus destinés à la vente (73%) qu’à l’autoconsommation (27%) et les marchés locaux représentent les principales plateformes commerciales. [less ▲]

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See detailSystème d’exploitation et potentialités économiques des cuvettes oasiennes du sud-est du Niger
Malam Boukar, Awa Krou; Yamba, Boubacar; Lebailly, Philippe ULg

Poster (2016, September 28)

Les cuvettes oasiennes du sud-est nigérien sont sources de production alimentaire (JAHIEL. 1998). C’est pourquoi, les populations locales sont dépendantes des cuvettes pour leurs productions alimentaires ... [more ▼]

Les cuvettes oasiennes du sud-est nigérien sont sources de production alimentaire (JAHIEL. 1998). C’est pourquoi, les populations locales sont dépendantes des cuvettes pour leurs productions alimentaires et leurs revenus (TYCHON B. et al. 2009). Cette étude vise à démontrer l’importance socio-économique des cuvettes oasiennes du sud-est nigérien. [less ▲]

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See detailINNOVATIVE INJECTABLE LIPOSOME AND DRUG-IN-CYCLODEXTRIN-IN LIPOSOME SYSTEMS ENCAPSULATING ESTETROL FOR THE TREATMENT OF ISCHEMIA DISEASES IN PREMATURE BABIES
Palazzo, Claudio ULg; Laloy, Julie; Delvigne, Anne-Sophie et al

Conference (2016, September 28)

Purpose: In 2010, almost 15 million of babies in the world are prematurely borned, 11.1 % of the total amount of alive children. Despite the better neonatology techniques, the number of preterm babies ... [more ▼]

Purpose: In 2010, almost 15 million of babies in the world are prematurely borned, 11.1 % of the total amount of alive children. Despite the better neonatology techniques, the number of preterm babies with motor, vision, hearing or mental deficiencies is still constant along the last twenty years. Moreover, no efficacy treatment is available to the present day. The estetrol (E4) has an important role in the brain development and protection. The aim of this study is to develop new injectable liposome and drug-in-cyclodextrin-in-liposome (DCL) formulations, encapsulating E4 in order to enhance its crossing through the blood-brain barrier (BBB). Methods: Hydroxypropyl-β-cyclodextrins (degrees of substitution 0.87 and 0.63) (HPβCD 0.87 and HPβCD 0.63) were used to increase E4 aqueous solubility. Liposome and DCL (E4-HPβCD 0.63 complex) formulations were prepared by thin-film hydration technique. The formulations were physicochemical characterized and stability in foetal bovine serum (FBS) was evaluated. LDH and MTS tests on endothelial, neuronal and BBB model cells were performed in vitro on the liposome formulation. Hemocompatibility of the formulations was evaluated on red blood cells, platelet aggregation and coagulation. BBB passage tests were performed using human BBB cell line (hCMEC/D3). Results: E4-HPβCD complexes proportionally increased the solubility of the hormone. Due to the lower solubility obtained with HPβCD ds 0.87, only HPβCD ds 0.63 was retained for future tests. Liposomes and DCL encapsulating E4 were prepared. All the formulations had average particle size below 150 nm, polydispersity index below 0.10 and ζ potential around + 30 mV. The encapsulation efficacy for liposomes was between 3% and 10% while those of DCL are between 15% and 35%. Moreover, the formulations are capable to release 80 % (liposome) and 90 % (DCL) of encapsulated E4 after 3 h at 37°C. The formulations, incubated in FBS at 37°C under gentle stirring, keep the same size and do not form protein corona up to 6 h. The effect of liposome and DCL formulations on cell viability and integrity was evaluated. The results showed no toxic effects on all the tested cell lines. Hemocompatibility tests showed no hemolysis, platelet aggregation or effects on coagulation, confirming the possibility of the formulations to be intravenously administrated. Preliminary BBB passage tests highlighted the capability of the formulations to pass the BBB and reach the brain. Conclusions: New non-toxic, hemocompatible liposome and DCL formulations encapsulating E4 were prepared. The formulations are promising drug delivery system to target estrogens to the brain, due to their physiochemical characteristics. Aknowledgment : The authors thank Estetra SPRL for providing Estetrol. [less ▲]

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See detailPratiques foncières dans les cuvettes oasiennes du Niger oriental
Malam Boukar, Awa Krou; Yamba, Boubacar; Ouassa, Tiekoura et al

Conference (2016, September 28)

La situation foncière en Afrique de l’Ouest francophone rurale se caractérise par la coexistence de différents systèmes de normes : aux règles foncières sociales, issues d’hybridations successives, se ... [more ▼]

La situation foncière en Afrique de l’Ouest francophone rurale se caractérise par la coexistence de différents systèmes de normes : aux règles foncières sociales, issues d’hybridations successives, se superpose un système juridique et réglementaire étatique (LAVIGNE Ph. 2000). L’Etat du Niger s’est engagé depuis les années 80 dans un processus visant à mettre en place des règles de gestion durable du foncier à travers le Code rural (Code Rural du Niger. 2013). De ce fait, la mise en perspective des spécificités des cuvettes oasiennes du Niger oriental ainsi que le cadre législatif devant permettre de gérer théoriquement le foncier est d’un intérêt croissant étant donné le nombre de problèmes récurrents et conjoncturels dans cette zone (ensablement, pression démographique, conflit foncier, enclavement). À la suite de ces constats, la mise en place de notre protocole de recherche tente d’établir un état des lieux du mode de fonctionnement et d’accès aux cuvettes oasiennes. La question de recherche s’énonce comme suit : « Comment s’effectue la pratique foncière dans les cuvettes oasiennes du département de Gouré ? ». La principale hypothèse du travail repose sur le fait que l’ensemble des cuvettes oasiennes du département de Gouré ont une gestion foncière relativement dépendante des chefs coutumiers et que ces derniers ne sont pas impliqués dans le processus du Code Rural Nigérien. [less ▲]

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See detailMathematical modelling of ectopic bone formation in bone morphogenetic (BMP) carrier device
Manhas, Varun ULg; Carlier, Aurelie; Geris, Liesbet ULg

Conference (2016, September 28)

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See detailClimatic and management drivers of CO2 exchanges by a production crop: Analysis over three successive 4-year crop rotation cycles
Buysse, Pauline ULg; Manise, Tanguy ULg; De Ligne, Anne ULg et al

Poster (2016, September 27)

Carbon dioxide (CO2) exchanges between crops and the atmosphere are influenced by both climatic and crop management drivers. The investigated crop, situated at the Lonzée Terrestrial Observatory (LTO ... [more ▼]

Carbon dioxide (CO2) exchanges between crops and the atmosphere are influenced by both climatic and crop management drivers. The investigated crop, situated at the Lonzée Terrestrial Observatory (LTO, candidate ICOS site) in Belgium and managed for more than 70 years using conventional farming practices, was monitored over three complete sugar beet/winter wheat/potato/winter wheat rotation cycles from 2004 to 2016. Continuous eddy-covariance measurements and regular biomass samplings were performed in order to obtain the daily and seasonal Net Ecosystem Exchange (NEE), Gross Primary Productivity (GPP), Total Ecosystem Respiration (TER), Net Primary Productivity (NPP), and Net Biome Production (NBP). Meteorological data and crop management practices were also recorded. Over the 12 years, NEE was negative (-4.34 kg C m-2) but NBP was positive (1.05 kg C m-2), i.e. as soon as carbon exportation by harvest and carbon importation (manure, slimes) are included in the budget, the site behaves as a carbon source. At the crop rotation scale (4 years) it was quite remarkable to observe that NBP was very similar over the three rotations (0.30-0.36 kg C m-2), despite climatic and management differences between years. Crop type impacted carbon exchanges, with sugar beet and winter wheat crops leading to higher net carbon sequestration than seed potato crops. For one given crop, larger growth length and cumulated global radiation drove larger cumulated NEE. Net carbon emissions were observed during intercrops, but growing mustard during these periods reduced their rates and provided carbon residues to the soil. NBP values suggest that one sixth of the total soil organic carbon stock at LTO (6.23 ± 0.16 kg C m-2 in [0, 60] cm) would be lost in 12 years. Large uncertainties (mostly due to biomass measurements) affect NBP estimates, but still, this figure is huge and should encourage cultural practices returning carbon to the soil. [less ▲]

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See detailOccurrence of greenhouse gases (CO2, N2O and CH4) in groundwater of the Walloon Region (Belgium)
Jurado Elices, Anna ULg; Borges, Alberto ULg; Hakoun, Vivien et al

Conference (2016, September 27)

Carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) can be indirectly transferred to the atmosphere through groundwater discharge into surface water bodies such as rivers. However, these emissions ... [more ▼]

Carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) can be indirectly transferred to the atmosphere through groundwater discharge into surface water bodies such as rivers. However, these emissions are poorly evaluated and highly uncertain. The aim of this work is identify the hydrogeological contexts (alluvial, sandstone, chalk and limestone aquifers) and in situ conditions which are most conducive to the generation and occurrence of GHGs in groundwater at a regional scale. To this end, CO2, CH4 and N2O concentrations as well as major and minor elements were monitored (n=37 samples) in two field campaigns (09/2014 and 03/2015) in 15 groundwater bodies of the Walloon Region (Belgium). This preliminary work, which was presented in the 42st IAH conference (Rome, Italy), shown that GHG concentrations range from 5,160 to 47,544 ppm from the partial pressure of CO2 and from 0 to 1,064 nmol/L and 1 to 5,637 nmol/L for CH4 and N2O respectively. Overall, groundwater was supersaturated in GHGs with respect to atmospheric equilibrium, suggesting that groundwater contribute to the atmospheric GHGs budget. A third sampling campaign is carried out in 2016 including around 60 new groundwater samples. The combination of the results of the three campaigns allows: (1) reducing the uncertainties related to indirect emissions of GHG through groundwater-surface water interaction and (2) contributing to a better understanding of the occurrence of GHGs in aquifers. New results will be presented and discussed in detail in the presentation. [less ▲]

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See detailDEVELOPMENT OF NOVEL CATIONIC AND LIGAND-GRAFTED ANIONIC LIPOSOMES FOR BRAIN-TARGETED DRUG DELIVERY
Karim, Reatul ULg; Palazzo, Claudio ULg; Laloy, Julie et al

Poster (2016, September 27)

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See detailAn old slate mine as lower reservoir for UPSH (Underground Pumping Storage Hydroelectricity)- groundwater interactions and limitations
Bodeux, Sarah ULg; Pujades, Estanislao ULg; Orban, Philippe ULg et al

Conference (2016, September 27)

Renewable energy sources have an increasing role to play in the future energy framework but their intermittence cannot afford a stable production according to the demand. Pumped Storage Hydroelectricity ... [more ▼]

Renewable energy sources have an increasing role to play in the future energy framework but their intermittence cannot afford a stable production according to the demand. Pumped Storage Hydroelectricity (PSH) is an efficient technology to store and release electricity. However, the development of new PSH plants is limited by environmental and topographic constraints. An innovative alternative consists in using old underground mines as lower reservoirs of Underground Pumped Storage Hydroelectricity (UPSH) plants. In this configuration, large amount of water is pumped and injected in underground cavities and these cyclic stresses impact the groundwater system. A hybrid 3D finite element mixing cell method is used to numerically simulate the use of an UPSH facility, in the case of an abandoned slate mine. Different scenarios are computed with varying pumping injection time-sequences. In order to assess the impact on the surrounding groundwater conditions, the resulting head evolution in the cavity and at different distances is analyzed in terms of groundwater oscillation magnitude, drawdown, and seepage into the cavity. Results show clearly the influence of the pumping injection time-sequence (rates, regularity, timing and duration of no-activity periods) on the actual head evolution in the surrounding medium and consequently on the magnitude of interactions with the cavity. For a given hydraulic conductivity of the surrounding medium (i.e. slates in this case study), the main conclusion is that the resulting interaction seepage flows (in and out of the cavity) are highly dependent on the chosen pumping injection sequences. The future impact of UPSH operation must be assessed taking this fact into account. [less ▲]

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See detailGenomics and ecological adaptation: metal hyperaccumulation in Arabidopsis halleri
Hanikenne, Marc ULg

Conference (2016, September 27)

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See detailComparison of temperature from DTS and ERT with direct measurements during heat tracer experiments in heterogeneous aquifers
Nguyen, Frédéric ULg; Hermans, Thomas ULg; Jamin, Pierre ULg et al

Conference (2016, September 27)

Geothermal field characterization and heat tracer experiments often rely on scarce temperature data collected in boreholes. Electrical resistivity tomography (ERT) and distributed temperature sensing (DTS ... [more ▼]

Geothermal field characterization and heat tracer experiments often rely on scarce temperature data collected in boreholes. Electrical resistivity tomography (ERT) and distributed temperature sensing (DTS) have the potential to provide spatial information on temperature changes in the subsurface. In this contribution, we show how DTS and ERT have been used to investigate the heterogeneity of a heterogeneous aquifer during a heat tracing experiment under forced gradient conditions. Optic fibers were installed in the heat injection well and in two piezometers intersecting the main flow directions at 8 m from the injection well. These piezometers were also equipped with ERT. The DTS measurement in the injection well clearly shows the two-layer nature of the aquifer. After the end of injection, the temperature in the bottom part of the well decreases faster than in the upper part due to the higher water fluxes. Those results are confirmed by DTS measurements in natural flow conditions during a heating wire test. DTS and ERT in the cross-panel both show the vertical and lateral heterogeneity of the aquifer. Temperatures only increase significantly in the bottom part of the aquifer where advection is predominant. However, strong differences are observed laterally. ERT additionally shows that the hot plume is divided in two main flow paths, which is confirmed by direct temperature measurements. The comparison of DTS and ERT shows that one of the well is suffering from water mixing. Indeed, temperature from DTS are homogeneous over the whole tichkness of the aquifer, whereas ERT temperature, less affected by local variations, are varying. Our study demonstrate the value of spatially distributed measurements for the monitoring of heat tracer experiment and highligths the issue of multilevel sampling. The detailed temperature measurements can be subsequently used in hydrogeological model to better estimates heat flow and transport parameters. [less ▲]

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See detailLa fluidothérapie chez le bovin adulte
Lecomte, Denis; Casalta, Hélène ULg; Djebala, Salem ULg et al

Conference (2016, September 27)

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See detailInfluence of groundwater exchanges on the efficiency of Underground Pumped Storage Hydroelectricity plants using open pit mines
Pujades, Estanislao ULg; Bodeux, Sarah ULg; Orban, Philippe ULg et al

Poster (2016, September 27)

Underground Pumped Storage Hydropower (UPSH) plants can be used to manage the production of electrical energy according to the demand. These plants consist in two reservoirs, the upper one is located at ... [more ▼]

Underground Pumped Storage Hydropower (UPSH) plants can be used to manage the production of electrical energy according to the demand. These plants consist in two reservoirs, the upper one is located at the surface while the lower one is underground. The energy is stored by pumping water from the lower to the upper reservoir and produced by releasing water from the upper to the lower one. As a result, the hydraulic head in the lower reservoir varies continuously. UPSH plants interact with the surrounding aquifers exchanging groundwater. These groundwater exchanges, which play an important role in the evolution of the hydraulic head inside the underground reservoir, are a fact of concern in the selection of pumps and turbines because their efficiency varies with respect to the head difference between the two reservoirs. Therefore, the aquifer parameters should be considered in the selection of pumps and turbines. In this context, with an UPSH plant made up by an open pit mine, we study numerically (1) the influence of groundwater exchanges on the efficiency and (2) how the hydraulic head evolution varies depending on the aquifer properties. The relation among the groundwater exchanges, the efficiency of pumps and turbines and the aquifer parameters is considered by comparing the numerical results of several simulations. It is shown that groundwater exchanges are not negligible when optimizing the efficiency of UPSH plants. A priori, low hydraulic conductivity geological media were preferred to decrease interactions with the open-pit or the cavity used as lower reservoir. Taking into account the pump/turbine performance curves, it appears that, on the contrary, the global efficiency would be increased if the surrounding medium facilitates large groundwater exchanges because hydraulic head variations are softened. [less ▲]

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See detailSmall molecule ligands for the orphan GPR27
Dupuis, Nadine ULg; Franssen, Delphine ULg; Laschet, Céline ULg et al

Poster (2016, September 26)

Background G protein-coupled receptors (GPCRs) are involved in many physiological processes and constitute the target of around 30% of marketed therapies. Nonetheless, ~100 human GPCRs have no known ... [more ▼]

Background G protein-coupled receptors (GPCRs) are involved in many physiological processes and constitute the target of around 30% of marketed therapies. Nonetheless, ~100 human GPCRs have no known ligand and are designated as "orphan". This project focuses on GPR27, a rhodopsin-like alpha orphan of the SREB family (Super conserved Receptors Expressed in the Brain), presumably involved in the regulation of insulin secretion [1]. Methods In order to identify small molecules activating GPR27, we developed a firefly luciferase complementation assay (based on [2]) to assess the binding of ß-arrestin2 to the activated GPCR. To increase the affinity for and strengthen the interaction with ß-arrestin2, a GPR27-V2R chimera has been used for library screening. Results Small molecules activating GPR27-V2 have been identified in the DiverSetTM library (ChemBridge). After exclusion of non-specific activities using another unrelated GPCR, two compounds sharing a common scaffold with activity in the low micromolar range were selected for further investigations. We confirmed their agonist profile by performing complete concentration-response curves on our arrestin complementation assay as well as orthogonal assays. These compounds show good specificity being inactive on GPR85-V2 and GPR173-V2 (the two other SREB members). With these original tools, we characterized the recruitment of ß-arrestin2 to activated GPR27 WT. Conclusion We identified small molecule ligands for GPR27 that will serve as valuable tools for studying the pharmacology of GPR27 as well as its physiological roles, for example in insulin secretion. 1 Ku G.M., Pappalardo Z., Luo C.C., German M.S., McManus M.T. An siRNA Screen in Pancreatic Beta Cells Reveals a Role for Gpr27 in Insulin Production. PLoS genetics. 2012, 8, e1002449. 2 Takakura H., Hattori M., Takeuchi M., Ozawa T. Visualization and Quantitative Analysis of G Protein-Coupled Receptor−β-Arrestin Interaction in Single Cells and Specific Organs of Living Mice Using Split Luciferase Complementation. ACS Chem. Biol. 2012, 7, 901−910. [less ▲]

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See detailGroundwater flow and saltwater intrusion modelling in the Continental Terminal (CT) aquifer near the Saloum inverse estuary in Senegal
Faye, Serigne; Ndeye, Maguette Dieng; Orban, Philippe ULg et al

Conference (2016, September 26)

The Saloum River hypersaline estuary (Senegal) is an ‘inverse estuary’ showing a salinity increasing from the river mouth towards inland. This salinization process is mainly driven by a net loss of ... [more ▼]

The Saloum River hypersaline estuary (Senegal) is an ‘inverse estuary’ showing a salinity increasing from the river mouth towards inland. This salinization process is mainly driven by a net loss of freshwater due to intense evaporation. In this context, interactions between the river and the surrounding aquifer of the Continental Terminal (CT) may lead to local and progressive salinization of this groundwater main resource for water supply. Our study, based on available data and new measured data in 2012 and 2013, is focused on the southern part of the Saloum basin. It confirms that the groundwater resource is threatened by local saltwater intrusions in the vicinity of the Saloum River and along the western coastal part of the aquifer. For a long term water resources management, it is thus essential to predict the future evolution of this process in a context of increasing groundwater pumping rate together with climate variability and changes. A groundwater flow model is developed using MODFLOW. Starting from a conceptual steady-state situation corresponding to the CT aquifer state in 1973 before development of pumping, a transient calibration of the groundwater flow model is performed on data from 1974 to 2012. Despite the low number of measured data, the model can be considered as the current best assessment tool for future predictions. Using the particle tracking technique (MODPATH), a first assessment of the saltwater intrusions in the aquifer is simulated (neglecting the density effect on the hydraulic conductivity) confirming the measured data. Results, for an increased pumping of 20% in 2050 combined with different climatic scenarios, are useful to assess how the saltwater intrusions will evolve in the next years. [less ▲]

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See detailMUCOADHESIVE SPONGES WITH PEGYLATED LIPOPLEXES: TOWARDS A SUSTAINED VAGINAL DELIVERY OF siRNA
Furst, Tania ULg; Dakwar, Georges; zagato, Elisa et al

Poster (2016, September 26)

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See detailQuelles réponses face à la fatigue vocale? Variabilité inter-individuelle des modifications acoustiques de la voix au cours de la journée
Remacle, Angélique ULg; Gerber, Silvain; Garnier, Maëva

Poster (2016, September 26)

Objectifs: 1) décrire l’évolution de 4 indicateurs acoustiques de la fatigue vocale au cours d’une journée de travail et examiner leur universalité dans l'échantillon, 2) déterminer si différentes ... [more ▼]

Objectifs: 1) décrire l’évolution de 4 indicateurs acoustiques de la fatigue vocale au cours d’une journée de travail et examiner leur universalité dans l'échantillon, 2) déterminer si différentes typologies de réponse à la fatigue vocale peuvent être distinguées. Population: 22 enseignantes enregistrées le matin et le soir après leur journée de travail, à 3 temps de l’année: octobre, décembre, et février. Tâche: voyelle [a] tenue produite 5 fois à intensité et fréquence confortables. Paramètres mesurés avec Praat et moyennés sur les 5 répétitions: F0 (Hz), rapport harmoniques/bruit (HNR, dB), local Jitter (%), et local Shimmer (%). Les variations des moyennes entre le soir et le matin (Δ) sont calculées pour chaque paramètre. Résultats: En accord avec la littérature, le Δ moyen pour les 22 participantes aux 3 temps montre une augmentation de F0 et HNR, et une diminution de Jitter et Shimmer au cours de la journée. Cependant, ces résultats ne sont pas généralisés dans notre échantillon. Une analyse hiérarchique ascendante permet d'identifier 3 typologies de réponse à la fatigue vocale, observées suite à la journée de travail. Typologie 1: tendance inverse à la littérature (ΔF0 et ΔHNR négatifs, Δjitter et Δshimmer positifs). Comportement hypofonctionnel en réponse à la fatigue vocale. Typologie 2: tendance et amplitude similaires à la littérature (ΔF0 et ΔHNR positifs, Δjitter et Δshimmer négatifs). Réponse attendue, adaptation saine à la fatigue vocale. Typologie 3: tendance similaire à la littérature mais d’amplitude très marquée. Comportement hyperfonctionnel, suspicion d’un trouble vocal. [less ▲]

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See detailRelectures de La Misère du monde: Bourdieu, Sartre, Enzensberger
Cormann, Grégory ULg

Conference (2016, September 26)

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See detailLe développement de l’agriculture familiale par les transferts des migrants
Yao Namé, Juste Michel ULg; Lebailly, Philippe ULg

Conference (2016, September 25)

The following pages report the results of our survey conducted among (Malian, Senegalese and Mauritanian) Soninké migrants during the period of 14th to 4 December 2015, living in the social residences of ... [more ▼]

The following pages report the results of our survey conducted among (Malian, Senegalese and Mauritanian) Soninké migrants during the period of 14th to 4 December 2015, living in the social residences of the former home Pinel (first home of migrant workers in France). This survey had to aim to discuss the implementation and use of a new tool to transfer the money in order to reduce use of informal channels, to promote financial inclusion, to finance smallholding and to develop entrepreneurship in rural by granting of credits medium or long term via Microfinance Institutions (IMF). [less ▲]

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See detailAnalyse comparative des coûts de production rizicole dans les pays de la Communauté Economique des Pays des Grands Lacs (CEPGL).
Furaha Mirindi, Germaine ULg; Lebailly, Philippe ULg

Conference (2016, September 23)

Cet article fait une analyse comparative des résultats économiques de la production rizicole durant la saison B 2014 dans les trois pays de la CEPGL qui sont la République Démocratique du Congo, le Rwanda ... [more ▼]

Cet article fait une analyse comparative des résultats économiques de la production rizicole durant la saison B 2014 dans les trois pays de la CEPGL qui sont la République Démocratique du Congo, le Rwanda et le Burundi. L’approche comparative permet de trouver les explications des différences des résultats en partie dans les politiques mises en œuvre dans chaque pays. Les enquêtes ont été menées dans la plaine de la Ruzizi partagée entre les trois pays auprès de 240 producteurs du riz choisi à partir de la méthode des quotas sur la base d'une stratification des exploitations rizicoles. Dans le site congolais (où il est plus difficile d’accéder aux intrants et crédits), les coûts de production d’1kg de paddy sont les plus élevés avec une fonction de production y=0,034x+0,053z+0,422 et le rendement le plus bas (2698kgs). Par contre, dans les sites burundais et rwandais où l’Etat intervient dans l’approvisionnement en intrants et particulièrement dans le site rwandais, l’accès aux crédits, les fonctions de production sont respectivement de y=0,024x+0,031z+0,297 et y=0,017x+0,023z+0,269 avec des rendements de 3962kgs et 5339kgs dans le même ordre. Les coûts de production supportés sur un hectare rizicole ou encore pour la production d’une tonne de paddy varient selon le pays car ils dépendent de la valeur des intrants utilisés et des autres charges de structures. Ils varient ainsi de 1139,4USD à 1354,5USD/ ha et de 269 à 422USD/tonne. [less ▲]

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See detailUn morso di più: ecologia del cannibalismo in Salamandra salamandra
Melotto, Andrea; Manenti, Raoul; Ficetola, Francesco et al

Conference (2016, September 23)

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See detailApplications des relevés 3D au patrimoine, de l'acquisition au système d'information 3D
Hallot, Pierre ULg; Billen, Roland ULg; Poux, Florent ULg et al

Conference (2016, September 23)

Les techniques permettant l’acquisition 3D du patrimoine bâti sont maintenant assez mures et démocratiques pour être utilisées à grande échelle. De plus en plus d’édifices font l’objet d’une sauvegarde ... [more ▼]

Les techniques permettant l’acquisition 3D du patrimoine bâti sont maintenant assez mures et démocratiques pour être utilisées à grande échelle. De plus en plus d’édifices font l’objet d’une sauvegarde numérique sous la forme de nuages de points colorés. Il reste néanmoins de nombreux défis à relever notamment pour : harmoniser les pratiques d’acquisition en terme de qualité et de précision, assurer l’interopérabilité entre les jeux de données ; exploiter pleinement l’information ponctuelle collectée ; et proposer une visualisation adéquate de ces grands jeux de données. Dans le cadre des développements réalisés à l’Unité de Géomatique de l’ULg, nous travaillons à la mise au point de systèmes d’informations permettant d’assurer un lien entre les informations sémantiques issues des applications archéologiques, architecturales, d’histoire de l’art avec les modèles 3D réalisés. La mise en place de ces systèmes d’informations passe par plusieurs étapes de recherche relatives à la sectorisation automatique, les structures de données, la définitions d’ontologies thématiques et finalement les règles sémiologiques de représentations dans un environnement virtuel 3D. Au cours de cette présentation, nous proposons de parcourir trois projets de recherche en cours au sein de l’Unité afin l’illustrer nos propos. Nous présenterons plus particulièrement le cas de la cathédrale Saint-Paul de Liège. [less ▲]

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See detailInfluence d'un programme de revalidation multidisciplinaire post-cancer du sein sur la fonction physique
Leclerc, Anne-France ULg; Foidart-Dessalle, Marguerite ULg; BURY, Thierry ULg et al

in 9ème Congrès commun SFMES - SFTS : Abstract book (2016, September 22)

Objectif : Le cancer du sein ainsi que ses traitements sont à l'origine de nombreux effets secondaires indésirables, notamment sur la fonction physique. Cette étude a pour objectif de déterminer les ... [more ▼]

Objectif : Le cancer du sein ainsi que ses traitements sont à l'origine de nombreux effets secondaires indésirables, notamment sur la fonction physique. Cette étude a pour objectif de déterminer les bénéfices éventuels d’un programme de revalidation multidisciplinaire sur la santé physique des femmes ayant été traitées pour un cancer du sein et d'évaluer l'influence de certaines caractéristiques individuelles initiales sur la réponse du groupe expérimental au programme de revalidation. Matériel et méthodes : L'étude constitue un essai clinique contrôlé non-randomisé évaluant une population totale de 209 patientes, recrutées sur base du volontariat et réparties en deux groupes, soit un groupe contrôle (n = 106) et un groupe expérimental (n = 103). Ce dernier a bénéficié d’une revalidation de trois mois comprenant un entraînement physique supervisé à raison de trois séances par semaine et diverses sessions psycho-éducatives. Pour l'ensemble des participantes, des évaluations constituées d'une part de mesures physiques et fonctionnelles et d'autre part de mesures de composition corporelle ont été programmées à 0 et 3 mois. Celles-ci ont inclus un test de souplesse ("Sit and Reach"), un test d'effort maximal sur bicyclette ergométrique avec suivi cardio-respiratoire, un test de marche de six minutes et la mesure de l'indice de masse corporelle et du pourcentage de graisse corporelle. Afin d'affiner l'analyse, trois groupes ont également été constitués au sein du groupe expérimental à partir des caractéristiques individuelles de thérapie adjuvante (présence de chimiothérapie ou non), de chirurgie (mastectomie ou tumorectomie) et de délai de fin de traitement (délai ≤ 4 mois ou ≥ 8 mois). Résultats : Initialement, toutes les patientes présentent un état de déconditionnement physique, non influencé par le délai de fin de traitement ou par le type de chirurgie, mais bien influencé par la présence d'une chimiothérapie puisque la VO2max apparaît significativement plus faible dans ce cas. Au terme des trois mois, la souplesse (p < 0,0001), la consommation maximale d'oxygène (p < 0,0001), la puissance maximale aérobie (p < 0,0001) et la distance de marche en six minutes (p < 0,0001) s’améliorent significativement au sein du groupe expérimental. Au sein du groupe contrôle, aucune amélioration n'est constatée, excepté pour la distance de marche (p = 0,0031). Par ailleurs, une augmentation significative de l'indice de masse corporelle (p = 0,034) et du pourcentage de graisse corporelle (p = 0,034) est observée au sein du groupe contrôle alors que ce paramètre diminue significativement au sein du groupe expérimental (p = 0,037). Enfin, toutes les patientes du groupe expérimental présentent un même profil de progression quelles que soient leurs caractéristiques individuelles initiales. Conclusion : Cette étude démontre ainsi les effets bénéfiques, tant sur le plan physique que de la composition corporelle, d’une prise en charge multidisciplinaire chez des femmes ayant été traitées pour le cancer du sein. [less ▲]

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See detailPhosphate-based composite electrodes for Li/Na-ion batteries: upscalable solution syntheses with in-situ solid carbon addition
Vertruyen, Bénédicte ULg; Brisbois, Magali; Eshraghi, Nicolas ULg et al

Conference (2016, September 22)

Since the success story of lithium iron phosphate, other phosphate-based compounds have attracted a lot of interest as promising candidates for positive electrodes in lithium-ion or sodium-ion batteries ... [more ▼]

Since the success story of lithium iron phosphate, other phosphate-based compounds have attracted a lot of interest as promising candidates for positive electrodes in lithium-ion or sodium-ion batteries. Their electronic conductivity usually has to be improved through the preparation of composite powders ensuring intimate contact between the active material and conductive carbon. We report on the one-step synthesis of composite precursors using spray-drying or hydrothermal synthesis routes, two techniques which offer easy scaling-up of production. We show that addition of a solid carbon source (carbon black or carbon nanotubes) into the solution has a strong influence on the powder microstructure and is very effective in improving the battery cycling performance, taking our recent results on phosphates [Fex(PO4)(OH)y.zH2O)] and fluorophosphates [Na2FePO4F, Na3V2(PO4)2F3] as examples. We also compare this approach with the addition of the carbon source as a soluble precursor (such as ascorbic acid or citric acid) where the in situ formation of carbon is achieved by a heat treatment in inert atmosphere (typically argon). [less ▲]

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Peer Reviewed
See detailGAVRAY Claire (2016) The evolution of boys’ and girls’ attitudes and moods at the light of their historical opportunities : the case of violence and depression -
Gavray, Claire ULg

Conference (2016, September 22)

depression mood and violent behaviour are linked as a common dynamic amongst female teenargers but not amongst male ones ( twho different paths for them). The roots of depression and violence are ... [more ▼]

depression mood and violent behaviour are linked as a common dynamic amongst female teenargers but not amongst male ones ( twho different paths for them). The roots of depression and violence are connected to gender socialisation (importance of lack of recognition and negative life events in private sphere for girls and in public sphere for boys). [less ▲]

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See detailGlucose production: influence of the datasets choice on LCA results
Gerbinet, Saïcha ULg; Belboom, Sandra ULg; Léonard, Angélique ULg

Poster (2016, September 22)

The aim of this study is to have a good understanding of the environmental impact of glucose production. Glucose is generally produced from corn or wheat. Since agricultural processes are known to be ... [more ▼]

The aim of this study is to have a good understanding of the environmental impact of glucose production. Glucose is generally produced from corn or wheat. Since agricultural processes are known to be difficult to evaluate by LCA, the results obtained with two different LCA databases, Gabi and EcoInvent, are compared in this work. The production of glucose from raw materials can be divided in two steps: the agricultural step allowing the plant production, and the conversion step including the extraction of the starch from the plant and its hydrolysis into glucose. Preliminary results underline the high impact of the agricultural step, so a special attention has been paid to these data. Specific Belgian data collected by the Walloon Agricultural Research Centre (CRA-W) (2014) [1] have been used as primary data (yield, amount of fertilizers, etc.), either using EcoInvent or Gabi datasets background data to model fertilizers, diesel consumption, etc. A third model was built using only data available in Ecoinvent for corn and wheat cultures. For the conversion step, literature data have been used along with some industrial data. As few studies are available in the literature concerning starch hydrolysis, the focus has been placed on data validation (mass balance checks, cross-reference information, etc.). Based on these multiple sources, it is possible to compare the LCA results for the production of 1 kg of glucose for three different cases, summarized in the following table. Table 1: Summary of modelled cases Agricultural step Conversion steps Primary data Dataset Primary data Dataset Case 1 Belgian GaBi Literature + Industry GaBi Case 2 Belgian Ecoinvent Literature + Industry Ecoinvent Case 2 Ecoinvent Literature + Industry Ecoinvent The results obtained using these three models will be presented, at both the inventory and impact assessment steps. They show significant differences and highlight the need to understand in depth the involved assumptions when developing the datasets, in addition to the ones adopted for the inventory. [less ▲]

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See detailCompetition of phonon and magnon effects in the temperature dependence of spinwave stiffness
Ostler, Thomas ULg; Verstraete, Matthieu ULg; Di Gennaro, Marco ULg et al

Conference (2016, September 21)

Magnons are the elementary magnetic excitations in ordered solids. Understanding such collective excitations is important for a number of technologically relevant fields, such as, magnonics [1] or spin ... [more ▼]

Magnons are the elementary magnetic excitations in ordered solids. Understanding such collective excitations is important for a number of technologically relevant fields, such as, magnonics [1] or spin caloritronics [2]. The central interactions in spin caloritronics are the couplings of phonons with electrons and spin degrees of freedom. Furthermore, understanding the effects of temperature on the phonon and spin degrees of freedom adds a further complexity. In the present work we have developed a multiscale model of ferromagnetic materials and demonstrate the effect of temperature dependent phonon displacements on the magnons spectra. Our results show that the for Fe and Ni the effect of phonon displacements acts to reduce the Curie temperature, whereas for Permalloy the opposite is true due to an increased long-ranged exchange interaction. This increased exchange interaction results in an increasing spin-wave stiffness with increasing temperature, overcoming the usual decrease due to magnon softening. To determine the effects of increasing the phonon temperature we have developed a multiscale model whereby we begin by calculating the thermal displacement of phonons, $\sqrt{\langle u^2(T) \rangle}$, calculated using the phonopy software package [3] using electronic ground state and phonon properties determined using the ABINIT software package [4]. Then the exchange constants are determined using the SPRKKR package [5]. Finally, we use linear spin wave theory to determine the effect of the phonon temperature on the exchange alone, demonstrating an increasing frequency of the acoustic magnon branch. We take into account the thermal effects of the magnetic system through the use of the atomistic spin dynamics approach. Magnon softening due to thermal effects demonstrates a more modest increase in the exchange stiffness (over the purely phononic effect), however, an overall increase is still observed. \newline \newline [1] A. V. Chumak, V. I. Vasyuchka, A. A. Serga, and B. Hillebrands, Nature Physics, {\bf 11}, 453–461 (2015). \newline [2] G. E. W. Bauer, E. Saitoh, and B. J. van Wees, Nature Materials {\bf 11}, 391 (2012). \newline [3] Atsushi Togo and Isao Tanaka, Scr. Mater., {\bf 108}, 1-5 (2015) \newline [4] X. Gonze \textit{et al.} Computer Physics Communications {\bf 180}, 2582-2615 (2009). \newline [5] T. Huhne \textit{at al.} Physical Review B, {\bf 58}, 10236 (1998). [less ▲]

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See detailDie Familie von Medem. Zur Verbindung von Bildung, Literatur und Politik in Kurland
Leyh, Valérie ULg

Conference (2016, September 21)

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See detailThe role of meetings in building modern organisational governance systems - outlining a sociological approach to meetings
Thunus, Sophie ULg

Conference (2016, September 21)

By relying on empirical and micro level analyses of the implementation of a Belgian reform of mental healthcare delivery, this paper shows that inter-organisational and interinstitutional meetings might ... [more ▼]

By relying on empirical and micro level analyses of the implementation of a Belgian reform of mental healthcare delivery, this paper shows that inter-organisational and interinstitutional meetings might be conceived as key sites for the realisation of public policy objectives; i.e. sites where both the meaning of policy objectives and the social systems through which they are enacted are (re)defined. This paper is based on a case study on the implementation process of the ongoing Belgian reform of mental healthcare delivery, called “Reform 107”. Reform 107 is designed to shift mental healthcare organisation from the model of residential psychiatry, which is centred on medical hospital care, to community psychiatry that implies, instead, psychosocial home and/or ambulatory care. Policymakers conceived this shift through the development of local mental healthcare networks, which are defined as concrete partnerships between local, residential and ambulatory care providers and social and employment public services. The first stage in the implementation process consisted in four-year exploratory projects through which local actors were expected to refine the community care model proposed by policymakers. By asking local actors to participate in the adaptation of the model to local realities, policymakers intended to improve their own knowledge of local mental healthcare systems on the one hand, and to interest local actors in a reform that challenges their institutional interests on the other. Our analyses of the implementation of Reform 107 focused on three local exploratory projects and their monitoring by federal public health authorities. The empirical material was collected through semi-structured interviews (N=62) with policymakers and local actors, direct observations of the meetings between local mental health practitioners responsible for the reform’s implementation (N=65) and documentary analyses, including policy and (local) organisational documents. This material was first analysed by relying on a sociological frame of analysis based on the French sociology of organisations (Friedberg, 1997) and the interactionist sociology (Abbott, 2005; Bucher & Strauss, 1961; Corbin & Strauss, 2008). The resulting sociological account (Thunus, 2015) stressed that local models of governance, power struggles as well as professional knowledge significantly impacted on the development of mental healthcare networks. It also highlighted the use of new techniques by federal public health authorities to manage the reform implementation. Those techniques, including the multiplication of meetings with local actors, direct coaching of local projects’ leaders as well as training of front-line mental health professionals, were conceived as means to oppose strategies of resistance usually enacted by psychiatric hospitals (S Thunus & Schoenaers, 2012). This paper offers to refine this analysis by focusing on the specific role played by meetings in policy implementation, based on a conception of “the practice of policy-making”(Richard Freeman, Griggs, & Boaz, 2011). It draws on the observation that, though researches on policy implementation increasingly evoke meetings as part of the policy process, they do not properly address the role played by meeting in influencing, orienting and possibly (re)defining policy reforms. Indeed, following the recognition of the need for dealing with complex and uncertain problems, or wicked problems (Roberts, 2000), by relying on procedural policy instruments (Howlett, 2000) and collaborative governance (Emerson, Nabatchi, & Balogh, 2011), numerous researches focused on policy networks, hybrid forums (Callon, Lascoumes, & Barthes, 2001) and special committees whose activities involve meetings. However, by considering meetings as a part of/a tool for larger processes as problems solving, crisis resolution or decision-making, those researches made them unproblematic means to achieve predefined and external objectives. The problems resulting from a “meetings as a tool approach” (Schwartzman, 1989) are twofold. On the one hand, it seems to ignore that, by bringing different and specialised expertise together, meetings induce social, cognitive and technical challenges. Those challenges, including the sharing of specialised knowledge and harsh negotiations between actors defending institutional interests and professional jurisdictions, make meetings conflicting and problematic arenas (Cohen, March, & Olsen, 1972). On the other, when conceived as rational means to reach external objectives, meetings often appear as disappointing and pointless. Based on this observation, Schwartzman (1989) proposed to stop seeing meeting as part of larger processes as decision-making (as a tool), to focus on what meetings actually do to the organisation or social context in which they take place (i.e. to consider meetings as a topic). By drawing on Schwartzman’s invitation to make meetings a research topic, we propose to ask the question of what inter-organisational and interinstitutional meetings actually did to the Belgian mental health care reform. We suggest addressing that question by relying on a conception of policy-making as a practice of a special kind (R Freeman, Griggs, & Boaz, 2011). This conception insists on the role played by policy practices as meeting and talks in determining policy objectives and creating groups supporting them. Accordingly, we will focus on social actions and interactions unfolding through meetings and talks, to see how they use and produce knowledge, instruments and relationships both embodying and reshaping their environment. Finally, by inviting us to bracket the explicit objectives of the observed meetings (e.g. providing policymakers with an operational definition of care functions included in the proposed community model), this approach will enable us to see what inter-organisational and interinstitutional meetings actually do to policy reforms. That is, generating performances (Goffman, 1959) supporting collective enactments of new social and professional roles and artefacts that (re) constitute the meaning of the reform and the associated social system. Viewing meeting as a concrete policy practice thus helps to stress that they contribute to durable and deep change in their social environment, precisely by generating talks that largely exceed/displace their explicit mandate. [less ▲]

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See detailStudy on contribution of lipids towards the mechanical properties of milk fat globule membrane monolayer
Malik, Priyanka ULg; Danthine, Sabine ULg; Blecker, Christophe ULg

Conference (2016, September 20)

Milk fat globule membrane (MFGM) stabilizes fat globule in milk in form of emulsion. The primary monolayer of MFGM is rich in proteins and secondary bilayer is rich in polar lipids. MFGM finds application ... [more ▼]

Milk fat globule membrane (MFGM) stabilizes fat globule in milk in form of emulsion. The primary monolayer of MFGM is rich in proteins and secondary bilayer is rich in polar lipids. MFGM finds application as an additive in dairy and food industry (e.g. emulsions, infant formulas & reduced-fat products) for its emulsifying and stabilizing properties. MFGM received much attention in recent years due to both its health- beneficial & technological functionalities. This work has been carried out with the objective to understand contribution of various components towards the surface properties of complete MFGM. MFGM was isolated from fresh raw cream. During isolation of MFGM apart from polar lipids and MFGM proteins, neutral lipids are also isolated which have their origin in fat globules but are often considered as a constituent of MFGM. The MFGM was further fractioned into lipid fraction, defatted fraction and polar lipids. The mechanical properties of monolayer were studied for the above fractions using Langmuir film balance. Study of surface properties can also be linked to their techno-functional properties by calculating film elasticity of the compression isotherm which can be linked to emulsifying and stabilizing properties. The analysis of compression isotherms revealed that film elasticity is highly influenced by polar lipids. The behaviour of the MFGM appeared to be influenced by neutral lipid and defatted fraction during beginning of compression and by polar lipids at the end of compression. [less ▲]

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See detailValorization of Seeds from Some Field Border Flowering Seeds
Paul, Aman ULg; Danthine, Sabine ULg; Mutwale Kapepula, Paulin ULg et al

Poster (2016, September 20)

Flowering strips are now being increasingly cultivated along the fields to improve biodiversity. However after serving for the desired function, these plants have no utilization besides animal feed. It ... [more ▼]

Flowering strips are now being increasingly cultivated along the fields to improve biodiversity. However after serving for the desired function, these plants have no utilization besides animal feed. It could be really interesting to valorize some commonly grown plant in these strips to render food or health promoting compounds. With this objective in mind the seeds of Achillea millefolium, Anthriscus sylvestris and Prunella vulgaris were investigated for lipids, proteins and phenolic content. Further the lipids were analyzed for fatty acid profile using gas chromatography and the phenolic compounds in the methanolic extract of defatted seeds were identified using HPLC-DAD. The antiradical activity of the methanolic extracts obtained from defatted seeds was investigated using DPPH and ABTS assays. The anti-inflammatory potential of these seed extracts was evaluated on the reactive oxygen species (ROS) production by stimulated neutrophils and on the specific activity of myeloperoxidase (MPO), a pro-oxidant enzyme marker of inflammation. Seeds from all three plants were analyzed with interesting levels of lipids, proteins and phenolic content. Linoleic acid, oleic acid and alpha-linolenic acid were the major fatty acids analyzed in A. millefolium, A. sylvestris and P. vulgaris respectively. On the other hand different phenolic acid formed the major phenolic constituents. Seed extracts displayed high ABTS and DPPH radical-scavenging activities in a dose dependent manner. Also a strong dose dependent anti-inflammatory activity of all three extracts was observed against ROS production by neutrophils and MPO activity. Results indicate that these seed show a great potential to render lipids which could be utilized as human food, further the defatted seeds could be directly included in human diet due to interesting levels of proteins and anti-inflammation ability. [less ▲]

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See detailRelationships between mind-wandering, personal goals processing, and future thinking.
Stawarczyk, David ULg; D'Argembeau, Arnaud ULg

Conference (2016, September 20)

Mind-wandering refers to the occurrence of thoughts whose content is both decoupled from stimuli present in the immediate environment and unrelated to the task currently being carried out. Although this ... [more ▼]

Mind-wandering refers to the occurrence of thoughts whose content is both decoupled from stimuli present in the immediate environment and unrelated to the task currently being carried out. Although this phenomenon has been the object of increasing interest from the scientific community during le last decade, proportionally few studies have attempted to clearly determine the form, content, and possible functions of this particular kind of cognitions. In this presentation, we will review recent evidence from studies mainly performed in our lab suggesting that most instances of mind-wandering refer to the anticipation and planning of future events and are also closely related to the processing of personal goals. More specifically, we will first discuss the findings from behavioral research that examined the phenomenological features of mind-wandering with the use of experience sampling procedures during laboratory tasks. Results of these studies mainly revealed that most of reported mind-wandering episodes are temporally oriented towards the future and that this ‘prospective bias’ can be increased when participants’ attention had been oriented toward their personal goals prior to performing the tasks. We will next review the results of neuroimaging studies that investigated the neural correlates of mind-wandering and we will more specifically focus on meta-analytic evidences suggesting that the neural correlates of mind-wandering strongly overlap with those associated with episodic future thinking and personal goal processing. Together, these results suggest that mind-wandering may have an important adaptive value and could in particular play a key role in planning and preparing for upcoming events related to the individuals’ personal goals. [less ▲]

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See detailDynamic interactions of a supercritical aerofoil in the presence of transonic shock buffet
Giannelis, N. F.; Vio, G. A.; Dimitriadis, Grigorios ULg

in Proceedings of the International Conference on Noise and Vibration Engineering, ISMA 2016 (2016, September 19)

Within a narrow transonic flight region, shock-wave/boundary-layer interactions yield large amplitude, self sustained shock oscillations that are detrimental to both platform handling quality and ... [more ▼]

Within a narrow transonic flight region, shock-wave/boundary-layer interactions yield large amplitude, self sustained shock oscillations that are detrimental to both platform handling quality and structural integrity. In this study, the aeroelastic interactions between this transonic buffet instability and a spring-suspended supercritical aerofoil are investigated by means of Reynolds-Averaged Navier-Stokes simulations. Single degree-of-freedom pitching simulations are performed for a range of structural to aerodynamic frequency ratios, sectional mass ratios and levels of structural damping. The results show that for a range of pitch eigenfrequencies above the fundamental buffet frequency, sychronisation of the aerodynamic and structural modes occurs. This so called lock-in phenomenon acts as a mechanism for large amplitude Limit Cycle Oscillation in aircraft structures within the transonic flow regime. The sectional mass and the addition of structural damping are both found to have a pronounced effect on the nature of the limit cycles [less ▲]

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See detailImpact du nombre d’alternatives lors d’une tâche de reconnaissance à choix-forcé sur les processus de reconnaissance dans le vieillissement normal
Simon, Jessica ULg; Gilsoul, Jessica ULg; Bastin, Christine ULg

Poster (2016, September 19)

Les tâches de reconnaissance à choix forcé sont classiquement utilisées pour évaluer la mémoire de reconnaissance. Cependant, aucune étude n’a spécifiquement investigué l’impact du nombre d’alternatives ... [more ▼]

Les tâches de reconnaissance à choix forcé sont classiquement utilisées pour évaluer la mémoire de reconnaissance. Cependant, aucune étude n’a spécifiquement investigué l’impact du nombre d’alternatives sur les performances mnésiques des participants âgés. Nous voulons déterminer, d’une part, si le nombre d’alternatives proposées - deux ou trois – et d’autre part, si le degré de similarité entre la cible et ses leurres ont un impact sur les stratégies de récupération mises en place au cours de la tâche. Pour ce faire, nous avons recruté 20 participants jeunes et 20 participants âgés. Lors de la tâche de reconnaissance, nous leur avons demandé de choisir, parmi deux ou trois photographies de visages, celui qui a été présenté précédemment. Certains couples cibles-leurres étaient plus similaires que d’autres (partage de 60% de caractéristiques communes, contre 40%). Pour chaque item sélectionné, les participants devaient expliquer ce qui a guidé leur choix. Les premières analyses (ANOVA à mesures répétées 2 (groupes) x 2 (alternatives) x 2 (similarité) sur les deux dernières mesures, p<0,05) montrent que les performances entre les groupes sont équivalentes pour la tâche de reconnaissance à deux alternatives. A l’inverse, nous avons observé que les participants jeunes avaient significativement de meilleures performances que les âgés dans la tâche de reconnaissance à trois alternatives. Les profils mnésiques des participants seront étudiés à la lumière des modèles à deux processus de la reconnaissance. Nous faisons l’hypothèse d’un recours plus fréquent à la recollection chez les jeunes dans la tâche de reconnaissance à trois alternatives (vs deux alternatives), alors que le choix de l’item se ferait chez les âgés, en comparant directement les degrés de familiarité associés à chaque item et en sélectionnant le plus familier (Norman & O’Reilly, 2003). [less ▲]

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