References of "Scientific congresses and symposiums"
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See detailTowards new bioherbicides derived from barley root allelochemicals
Bouhaouel, Imen ULg; Gfeller, Aurélie; Fauconnier, Marie-Laure ULg et al

Conference (2015, October 09)

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See detailUnderstanding how people with MS get tired while walking
Pierard, Sébastien ULg; Phan-Ba, Rémy; Van Droogenbroeck, Marc ULg

in Multiple Sclerosis Journal (2015, October 09), 23(S11), 406

BACKGROUND. Walking impairment is frequent, appears early in the disease course of MS patients (MSP), and is perceived as the most disabling symptom. When walking, patients get tired more and differently ... [more ▼]

BACKGROUND. Walking impairment is frequent, appears early in the disease course of MS patients (MSP), and is perceived as the most disabling symptom. When walking, patients get tired more and differently than healthy people (HP) [Phan-Ba et al PLOS 2012]. This limits their walking perimeter. Understanding this phenomenon is thus important to suggest adequate therapies at the right time. OBJECTIVE. Our aim is to understand how MSP get tired while walking compared to HP. Two groups of MSP are considered: those with a low disability level (MSPL) and those with a high one (MSPH). We consider two criteria to measure the disability: the EDSS and the deceleration index (DI) [Phan-Ba et al PLOS 2012]. The limit between the groups is set at DI=0.8 and EDSS=3 (inclusive for MSPL). METHODS. Many gait characteristics (GC) have been measured with the system GAIMS along a 500m path walked as fast as possible. The dataset gathers 464 visits of HP and 70 of MSP. Some people have been assessed several times. There are 33 visits in the group MSPL with the EDSS criterion, and 25 with the DI criterion. Statistical tests (Welch) were performed on the differences and relative differences of the GC measured during the first and last 100m of the test to detect differences between HP and MSPL, and between MSPL and MSPH, as in [ECTRIMS 2012 P755]. RESULTS. Both criteria for defining the groups lead to similar conclusions. For many GC, the distributions of the variations are significantly different between MSPL and MSPH. The largest difference is for the relative difference of speed (p=0.000119 for EDSS and p=0.000021 for DI). In contrast, only the variation of the average lateral distance between the feet, which is related to the size of the base of support (and thus to the balance) shows a very significant difference between HP and MSPL (p=0.000116 for EDSS and p=0.000120 for DI). The balance does not seem to change much from MSPL to MSPH. Besides, we note that the variance decreases slightly from HP to MSPL and increases a lot from MSPL to MSPH. CONCLUSIONS. Statistically, from the motor fatigue point of view, it seems that the course of the MS disease is divided in two different stages. In the first one, MSP get more tired than HP because of a deterioration of the balance. Then, in the second one, their fatigue becomes related to a faster decrease of the walking speed. This suggests that physical therapy exercises focused on the balance could be given to MSP in the early stage of the disease. [less ▲]

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See detailDefining a score based on gait analysis for the longitudinal follow-up of MS patients
Azrour, Samir ULg; Pierard, Sébastien ULg; Van Droogenbroeck, Marc ULg

in Multiple Sclerosis Journal (2015, October 09), 23(S11), 408-409

BACKGROUND. The project GAIMS [ECTRIMS 2013 P800] aims at developing a gait measuring system particularily suited for the clinical routine, and providing a reference database with the gait characteristics ... [more ▼]

BACKGROUND. The project GAIMS [ECTRIMS 2013 P800] aims at developing a gait measuring system particularily suited for the clinical routine, and providing a reference database with the gait characteristics of many MS patients (MSP) and healthy people (HP). As the gait impairments are related to the disease progression, defining an objective and quantitative score based on the gait characteristics would be useful for the longitudinal follow-up. Based on the dataset of GAIMS and machine learning techniques (MLT), a score, well correlated with the EDSS, can be defined [Azrour et al. ESANN 2014]. OBJECTIVE. Burggraaff et al. [ECTRIMS 2014 P033] showed that paired comparisons can help human raters to better judge the state of the patients. In the same spirit, we aim at predicting the difference of EDSS between two persons or between two visits of a same person, based on clinical gait measures. We show that the pairwise comparison strategy leads to a score (Gait-Score) well correlated with the EDSS and sensitive to small modifications of the gait. METHODS. The gait of 162 HP and 72 MSP (44 with EDSS>3) has been recorded and analyzed with GAIMS. The Gait-Score is defined using the MLT of [Geurts et al. 2006]. We can compute the Gait-Score of a person by comparing him to others with known EDSS, and compute the difference of Gait-Score of a same person at two different moments. We measure the merits of the Gait-Score by the correlation between the predicted Gait-Score and the EDSS, as well as the ability to detect subtle gait deteriorations among people with ataxia induced by a low dose of alcohol (data of [Piérard et al. ESANN 2014]). RESULTS. The Gait-Score is well correlated with the EDSS (Pearson’s correlation=0.8743). Moreover, it manages to detect a gait deterioration after a small alcohol intake for 19 persons out of 24 (79% correct) which is much better than what was obtained by visual inspection of neurologists (62% according to [Piérard et al. ESANN 2014]). CONCLUSIONS. Based on the accurate gait measures provided by GAIMS, we are able to derive a Gait-Score, automatically, that is well correlated with the EDSS. Moreover, this score is able to detect subtle deteriorations of the gait caused by a low dose of alcohol. These results reinforce our conviction that the use of an automatic method based on gait analysis is very promising for the longitudinal follow-up of MS patients and the assessment of the impact of new drugs and rehabilitation programs. [less ▲]

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See detailEffect of evolutionary miniaturization on the tempo and mode of diversification - An example from marine angelfishes
Frederich, Bruno ULg; Santini, Francesco; Konow, Nicolai et al

Conference (2015, October 09)

Evolutionary change in body size is a widespread phenomenon in animals. Numerous studies have highlighted evolutionary miniaturization, referring to the evolution of small body size, in various taxa. As ... [more ▼]

Evolutionary change in body size is a widespread phenomenon in animals. Numerous studies have highlighted evolutionary miniaturization, referring to the evolution of small body size, in various taxa. As other traits shift, decrease in size can be viewed as a morphological novelty that enables colonization of new “adaptive zones” and subsequent diversification (i.e. a “key innovation”). Thus, evolution to small body size is hypothesized to influence lineage, morphological and ecological diversification. Until now, few studies have tested this hypothesis and current supports are mixed. Here, we present a quantitative analysis of the radiation of Pomacanthidae (angelfishes), an iconic coral reef fish family where small taxa, the so called “pygmy angelfishes” of the genus Centropyge, appear to have evolved three-times. If an evolutionary decrease in size has acted as a key innovation during the evolutionary history of Pomacanthidae, we predict that diversification rates would be the highest in clades of pygmy angelfishes. We produced a time-calibrated phylogeny including 67 species, collected ecological data and quantified the body shape of 80 species using geometric morphometrics. Then, we tested the prediction by modelling macroevolutionary dynamics of diversification using the Bayesian Analysis of Macroevolutionary Mixture (BAMM) framework. BAMM results do not support a common macroevolutionary regime for every pigmy angelfish clades. Only the clade Centropyge Xiphypops shows higher rates of lineage and morphological diversification than the other clades of angelfishes. We show that miniaturization has few effects on the rate of diversification. The shifts in the tempo of diversification observed in C. Xiphypops might instead be related to a functional innovation of the feeding apparatus. Using the Pomacanthidae, we illustrate that miniaturization may not be a main factor in triggering increased of diversification rates at the family level. [less ▲]

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See detailStable isotope ratios suggest limited trophic importance of seagrasses for invertebrate consumers from Malagasy tropical polyspecific seagrass meadows
Michel, Loïc ULg; Wang, Haolin; Frederich, Bruno ULg et al

Conference (2015, October 09)

Polyspecific seagrass meadows are of critical ecological importance in tropical coastal zones. These ecosystems provide a wide range of socio-economical services to local populations. Meadows however ... [more ▼]

Polyspecific seagrass meadows are of critical ecological importance in tropical coastal zones. These ecosystems provide a wide range of socio-economical services to local populations. Meadows however undergo multiple threats linked to human activities (increased nutrient input, overfishing, invertebrate overharvesting, etc.). It is currently difficult to assess how seagrass meadows could respond to anthropogenic impacts due to poor knowledge of their functional ecology. Here, stable isotope ratios of carbon, nitrogen and sulfur were used to unravel trophic interactions ruling the food webs associated to seagrass beds of the Toliara Great Reef (SW Madagascar). The contributions of various potential food items (sediment-associated and suspended particulate organic matter, plankton, leaves, roots and epiphytes of 7 seagrasses and thalli of 7 dominant macroalgae) to the diet of 20 invertebrate taxa (one sea urchin, 2 sea stars, 2 sea cucumbers, 5 gastropods including one sea hare, one bivalve, 2 amphipods, one leptostracan, one cumacean 2 hermit crabs and 3 shrimps) were assessed using a Bayesian stable isotope mixing model. Model outputs revealed that important trophic diversity existed among the invertebrate assemblage. In some groups (e.g. hermit crabs and amphipods), resource use by morphologically and taxonomically close taxa was markedly different. Many of the dominant taxa heavily relied on macroalgae for their nutrition. On the other hand, few species apparently consumed seagrass tissues. Moreover, when they did, seagrass generally accounted for a minor portion of the diet only. Overall, our results suggest that seagrass grazing in meadows of the Toliara Great Reef could be lower than in other tropical areas. These discrepancies could be linked with seasonal variation in resource availability or with eutrophication. Higher nutrient load is indeed known to cause ecosystem phase shifts and it may induce diet shift to algivory in some invertebrate consumers. [less ▲]

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See detailProgramme d'étirement appliqué à l'épaule raide : conséquences fonctionnelles
Forthomme, Bénédicte ULg; Croisier, Jean-Louis ULg; COLLIGNON, Pierre ULg et al

Conference (2015, October 09)

Les athlètes de lancer présentent une mobilité passive gléno-humérale de l’épaule dominante spécifique avec une majoration de la rotation externe et une limitation de la rotation interne. La limitation ... [more ▼]

Les athlètes de lancer présentent une mobilité passive gléno-humérale de l’épaule dominante spécifique avec une majoration de la rotation externe et une limitation de la rotation interne. La limitation interne semble liée à une raideur capsulo-musculaire postérieure, favorisant les pathologies de l’épaule sportive. Matériel et méthodes Vingt hommes, sportifs d’armer / lancer (volley-ball, handball) et pratiquant au moins 6 heures d’entraînement depuis plus de 5 années ont participé à cette étude. Ils présentaient tous une raideur des structures postérieures évaluée en clinique. Lors de l’inclusion dans l’étude, 10 athlètes (22,5 ± 4 ans) étaient asymptomatiques, 10 (24,8 ± 4 ans) présentaient une épaule dominante symptomatique (≥ 3/10 sur l’EVA). Les athlètes ont étiré chaque jour leur épaule dominante (sleeper stretch et cross body arm) pendant 4 semaines (5 x 30’'). Avant et après le programme d’étirement des structures postérieures, ils ont subi un test isocinétique de force maximale des rotateurs internes et externes ainsi qu’une analyse tridimensionnelle définissant la cinématique scapulaire. Résultats Après 4 semaines d’étirement des structures postérieures, tous les athlètes ont montré un gain significatif de mobilité en rotation interne passive. Nous n’observons aucune modification de la cinétique scapulaire lors de l’analyse 3D après les étirements chez les athlètes asymptomatiques ; les athlètes symptomatiques présentent une diminution du tilt antérieur scapulaire au repos après les 4 semaines. L’évaluation isocinétique des rotateurs d’épaules après les étirements montrent uniquement une légère réduction (- 4% ; p < 0,05) de la force des rotateurs internes à 60°/s en concentrique chez les athlètes asymptomatiques. Les sportifs qui décrivaient des douleurs avant les étirements sont significativement améliorés après le programme de 4 semaines ; cette diminution de la douleur est corrélée au gain en rotation interne passive. Discussion L’étirement pendant 4 semaines des structures postérieures de l’épaule raide sportive permet une augmentation de la mobilité passive. Ce gain de mobilité est corrélé à la diminution de la douleur chez les athlètes symptomatiques. [less ▲]

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See detailVISA-PF: A Cross-Cultural Adaptation And Validation Of The VISA-P Questionnaire In French
Kaux, Jean-François ULg; Delvaux, François ULg; Oppong-Kyei, Julian et al

Poster (2015, October 08)

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See detailCharacterisation of TLR7/8 in equine pulmonary alveolar macrophages
Tosi, Irène ULg; Frellstedt, Linda; Pirottin, Dimitri ULg et al

Poster (2015, October 08)

Purpose of the study: In both human and equine athletes, viral infections are common causes of respiratory diseases and of a sudden deterioration of expected performances. In both species, the underlying ... [more ▼]

Purpose of the study: In both human and equine athletes, viral infections are common causes of respiratory diseases and of a sudden deterioration of expected performances. In both species, the underlying mechanisms are still unclear, and an involvement of Toll-Like Receptors (TLRs), a fundamental link between innate and adaptive immunity, has been advocated. Our objectives were to verify the presence of TLR7 and TLR8, responsible for the early anti-viral response in mammals, in equine pulmonary alveolar macrophages (PAMs) and to assess their function through specific stimulation. Methods used: Equine PAMs were collected by broncho-alveolar lavage (BAL), isolated by adherence and stimulated with specific TLR7/8 ligands (an imidazoquinoline compound and single-stranded RNA), mimicking a viral attack. The expression of TLR7/8 was evaluated by rt-PCR and the ligand-induced production of cytokines (type I-IFNs and TNF-α) was assessed via ELISA. Summary of results: Our study demonstrated the expression of TLR7/8 in equine PAMs. QPCR analyses showed a high relative expression of genes coding for TLR7 and TLR8 on equine PAM. Stimulation with specific TLR7/8 ligands resulted in significantly up-regulated production of IFN-β and TNF-α, thereby confirming that TLR7/8 are functional in equine PAMs and that they play a role in the early pulmonary antiviral response. Conclusions: This study shows that TLR7 and TLR8 are present and functional in equine PAM and that they could play a role in the early pulmonary antiviral response. In terms of future perspectives, it is interesting to suggest that the extensively demonstrated efficacy of TLR7 and TLR8 synthetic ligands in the treatment of viral diseases in human medicine could motivate the pursuit of clinical trials in the equine patient for the therapeutic management or prevention of viral respiratory infections. [less ▲]

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See detailCross-Cultural Adaptation And Validation Of The VISA-A Questionnaire In French
Kaux, Jean-François ULg; DELVAUX, François ULg; Oppong-Kyei, Julian et al

Poster (2015, October 08)

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See detailApplying Stable Isotopes Bayesian Ellipses (SIBER) to characterise trophic niches of large cetaceans from the north-Western Medterranean Sea
Pinzone, Marianna ULg; Michel, Loïc ULg; Ody, Denis et al

Poster (2015, October 08)

Diet composition and feeding preferences are of critical importance to understand a species' ecology; better knowledge of these matters is necessary for efficient conservation. Few is known on the trophic ... [more ▼]

Diet composition and feeding preferences are of critical importance to understand a species' ecology; better knowledge of these matters is necessary for efficient conservation. Few is known on the trophic ecology of Mediterranean cetacean populations and the elusiveness of these organisms limits acquisition of new information. Here, we analysed C and N isotopic ratios of skin biopsies of 17 fin whales Balaenoptera physalus, 15 long-finned pilot whales Globicephala melas and 25 sperm whales Physeter macrocephalus sampled through darting between summer 2010 and 2013 in the North-Western Mediterranean Sea. We subsequently used the SIBER R package to explore isotopic niche parameters as a proxy for trophic niches assessment. Fitting of standard ellipses to each species revealed that no niche overlap between the odontocetes and fin whales was present, in accordance with the lower trophic level of the latter. Moreover, overlap between the isotopic niches of the two odontocetes was limited, confirming resource partitioning between these two species. This could be linked with differences in hunting periods and depths and consequently in prey availability. Bayesian modelling of standard ellipses revealed that the isotopic niche of fin whales was larger than the two odontocetes in over 99.80% of 106 model simulations. It is the first time that such variability is observed in Mediterranean fin whales. This suggests possible exploitation of food items from different trophic levels (krill, small fishes) or from other regions, such as other areas in the Mediterranean Sea and the North-East Atlantic. Modelling also suggested that no meaningful differences were present in the width of isotopic niches of the two odontocetes. The very narrow isotopic niche of pilot whales is in strong contrast with the generalist feeding behaviour this species is believed to have according to literature analysis. Our results open new perspectives on the ecological role of Mediterranean cetaceans. [less ▲]

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See detailLandings profile of small-scale fisheries in Senegal: The case of the Kayar Marine Protected Area
Gueye, Ndiapaly; Diop, Mamadou; Denis, Antoine ULg et al

Poster (2015, October 08)

As marine fisheries in Senegal are in serious decline due to overexploitation, the management of sustainable fisheries requires effective tactics based on scientific data. In order to characterize the ... [more ▼]

As marine fisheries in Senegal are in serious decline due to overexploitation, the management of sustainable fisheries requires effective tactics based on scientific data. In order to characterize the current state of the artisanal fishery of the Kayar Marine Protected Area (MPA), a daily survey of fish landings was carried out between October 2013 and May 2015, and a database was created. Results showed that the landings are largely dominated by pelagic species in terms of weight. In total, 84 taxa were registered, including the species Sardinella aurita, which has been the most landed (30.5%), followed by Trichiurus lepturus (18.9%). These species are mainly captured by means of purse seine. The other types of fishing gear used in the area are the long line and the single line, which target particular species (e.g., Epinephelus aeneus). The temporal evolution of landings shows a period of abundance between May and June, while fishing effort is generally increasing. Regarding the spatial distribution, landings originate primarily from the MPA, where the landing per unit of effort was higher in the Angleterre area compared to other studied areas. These temporal and spatial variations seem to be related to the upwelling intensity which is highly seasonal, habitat features (i.e., presence of an underwater canyon in the MPA), the ecological behaviour of fish species and overexploitation. Our results confirm the need for detailed and extensive population monitoring across fish species. As a result of this study, we hope to provide the first essential information for the integrated management of fisheries in the Kayar MPA and its surrounding area. [less ▲]

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See detailEtats de conscience altérée: évaluation clinique et techniques d'imagerie
Martial, Charlotte ULg

Conference (2015, October 07)

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See detailVie, institutions, politique : le cas Bergson
Caeymaex, Florence ULg

Conference (2015, October 06)

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See detailDecrease of carbon tetrachloride (CCl4) over 2004-2013 as inferred from global occultation measurements with ACE-FTS
Mahieu, Emmanuel ULg; Bernath, P. F.; Boone, C. D. et al

Poster (2015, October 05)

In this contribution, we use infrared solar occultation measurements performed by the ACE-FTS (Atmospheric Chemistry Experiment – Fourier Transform Spectrometer) instrument onboard the SCISAT-1 Canadian ... [more ▼]

In this contribution, we use infrared solar occultation measurements performed by the ACE-FTS (Atmospheric Chemistry Experiment – Fourier Transform Spectrometer) instrument onboard the SCISAT-1 Canadian satellite (Bernath et al., 2005). Since its launch in August 2003, this spectrometer has been in continuous operation with no significant degradation of its performance, and global measurements are available from late February 2004 onwards, spanning now more than a decade. [less ▲]

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See detailEpistasis associated to inflammatory bowel disease (IBD) in humans
Gusareva, Elena ULg; Wei, Zhi; Traherne, J.A. et al

Poster (2015, October 05)

Gene-gene interactions underlie biochemical pathways and have been well demonstrated in model organisms. Very few examples exist on replicated epistasis in humans. Here, we performed genome-wide scans to ... [more ▼]

Gene-gene interactions underlie biochemical pathways and have been well demonstrated in model organisms. Very few examples exist on replicated epistasis in humans. Here, we performed genome-wide scans to detect epistasis associated to Crohn’s disease (CD) and ulcerative colitis (UC). We used extensive data of the IIBDGC consisting of 18277 and 14224 CD and UC patients, respectively, and ~34050 healthy controls from 15 European countries typed on the Immunochip. At first, we removed rare variants at MAF<0.05 and filtered common variants at linkage disequilibrium (LD) of r2>0.75. To limit our results to independent effects, SNPs on chromosome 6 (which contains the HLA locus), were furthermore pruned to ensure an LD of r2<0.35. We adjusted the binary traits, CD and UC, for population stratification by regressing out the first 5 principal components in R-3.0.1. The study cohorts were randomly stratified into two subgroups (referred as discovery and replication). We then performed screenings for epistatic interactions with new adjusted trait values in the two subgroups using multidimensional reduction tool MB-MDR with permutation-based (step-down MaxT) multiple testing correction and significance assessment at 0.05. We identified 14 and 6 SNP-pairs associated to CD and UC, respectively, which were concordant between the discovery and replication groups. All SNP-pairs involved concomitant variants located on the same chromosomes (for CD at 1p31.3, 5p13.1, 16q12.1 and for UC at 1p31.3, 6p21.3). A more detailed investigation of these findings, as well as the implementation of different analysis protocols, will further increase our understanding of possible epistatic mechanisms underpinning IBD. [less ▲]

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See detailCurrent trend in carbon tetrachloride from several NDACC FTIR stations
Hannigan, J.; Palm, M.; Conway, S. et al

Conference (2015, October 05)

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See detailDe l'application des mathématiques en biologie : acquis et perspectives
Brostaux, Yves ULg

Conference (2015, October 03)

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See detailLeucocytes and lipid particles filtration in suction blood during cardiopulmonary bypass: impact on kidney function evaluated with a monocentric prospective randomized study.
LAGNY, Marc-Gilbert ULg; KOCH, Jean-Noël ULg; BLAFFART, Francine ULg et al

Conference (2015, October 03)

OBJECTIVE: Cardiac surgery may be complicated by acute kidney injury (AKI). Cardiotomy suction during cardiopulmonary bypass (CPB) is deleterious. A few studies have demonstrated that shed mediastinal ... [more ▼]

OBJECTIVE: Cardiac surgery may be complicated by acute kidney injury (AKI). Cardiotomy suction during cardiopulmonary bypass (CPB) is deleterious. A few studies have demonstrated that shed mediastinal blood (SMB) suction during cardiopulmonary bypass (CPB) can increase inflammatory response and lipids emboli. These 2 factors contribute to the development of postoperative AKI. The RemoweLL (RemoweLeucoLipids, Eurosets™, Italy) filter is a recent designed cardiotomy with a multilayer filter for activated leucocytes filtration and a syphon for lipid particles sequestration. The SMB can be collected and filtered in this supplementary cardiotomy added to CPB circuit. The aim of this monocentric prospective study was to compare the specific RemoweLL cardiotomy filtration for suction blood during CPB and a conventional 40 µm filter (Admiral, Eurosets™, Italy). The primary goal was to evaluate the AKI within 48 hours after surgery using the Acute Kidney Injury Network classification (AKIN classification) but also measuring early specific biomarkers of AKI: serum Cystatine C and urinary neutrophil gelatinase-associated lipocalin (NGAL). METHODS: Sixty patients scheduled for elective cardiac surgery (aortic or mitral valvular combined or not with coronary bypass grafting) with a glomerular filtration rate (GFR) > 45mL/min. were randomly into 2 groups for SMB filtration: - Groupe 1 (n=30) with RemoweLL cardiotomy (Leucocytes and lipids filter); - Groupe 2 (n=30) with Admiral cardiotomy (conventional 40 µm filter). All components: venous reservoir, oxygenator and surface treatment were similar in both groups. [less ▲]

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See detailConclusions
Valenti, Gianluca ULg; Miesse, Hélène ULg

Conference (2015, October 02)

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See detailBaccio Bandinelli théoricien. Réflexions sur le "Libro del Disegno"
Marique, Charlotte ULg

Conference (2015, October 02)

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See detailNovel chitosan hydrogel for the treatment of osteoarthritis.
Henrotin, Yves ULg

Conference (2015, October 02)

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See detailBuilding a bridge between Liege and Asturias : the case of zinc
Peters, Arnaud ULg

Conference (2015, October 01)

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See detailLe droit de vote à distance: Emergence d'un objet de recherche et apport au champ de la sociologie électorale
Lafleur, Jean-Michel ULg

Conference (2015, October 01)

Dans cet article, nous présentons tout d’abord l’émergence du droit de vote à distance comme objet de recherche dans le champ la théorie politique et des études migratoires. Ces travaux caractérisés par ... [more ▼]

Dans cet article, nous présentons tout d’abord l’émergence du droit de vote à distance comme objet de recherche dans le champ la théorie politique et des études migratoires. Ces travaux caractérisés par leur dimension exploratoire, nous permettent toutefois de définir le droit de vote à distance et d’identifier les caractéristiques essentielles qui le différencie aujourd’hui des pratiques antérieures. Nous présentons ensuite les travaux sur la diffusion de la norme qui depuis moins d’une décennie ont constitué le principal angle d’entrée de la science politique sur le droit de vote à distance. Dans la troisième et dernière partie de l’article, nous défendons enfin l’intérêt d’une approche transnationale des questions électorales dans les études électorales. Cette approche, comme nous le défendons, permet d’éclairer non seulement le comportement des expatriés mais plus largement la transformation des pratiques électorales ici et là-bas. [less ▲]

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See detailLa prise en charge interdisciplinaire des patients lithiasiques réduit-elle à long terme le taux de geste urologique pour récidive ?
Castiglione, Vincent ULg; Pieroni, Laurence; Conort, Pierre et al

Poster (2015, October 01)

Certains patients lithiasiques sont hautement récidivants, malgré les progrès considérables en urologie et une prise en charge des facteurs de risque. Nous avons fait l’hypothèse qu’une prise en charge ... [more ▼]

Certains patients lithiasiques sont hautement récidivants, malgré les progrès considérables en urologie et une prise en charge des facteurs de risque. Nous avons fait l’hypothèse qu’une prise en charge interdisciplinaire au long court dédiée au diagnostic du processus lithogène, à l’analyse des causes de récidive, et à la détermination d'objectifs chiffrés de prévention, réduirait le nombre de gestes chirurgicaux pour récidive lithiasique et améliorerait ainsi la qualité de vie des patients. [less ▲]

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See detailChronos and Topos: The Inheritance of the Here-Now in Gail Jones’s Five Bells
Belleflamme, Valérie-Anne ULg

Conference (2015, October 01)

In an interview, Australian novelist, essayist, and academic Gail Jones claimed an interest in psycho-geography, i.e. “in the idea,” as she puts it, “that we must walk around our own place with an active ... [more ▼]

In an interview, Australian novelist, essayist, and academic Gail Jones claimed an interest in psycho-geography, i.e. “in the idea,” as she puts it, “that we must walk around our own place with an active intelligence and with a degree of radical attention to what is there.” Taking Sydney as an example, Jones insists on the importance of looking at the city’s “shapes, its motions,” of attending to its “sounds, corridors between spaces, the unexpected.” It is, she continues, “about apprehending things through shapes and signs.” Sydney, to her, is a place haunted by its colonial inheritance, and Australia, more generally, is a “colony of trauma”, a place where “there is always a tension between remembering and forgetting.” Thus time and space are merged, or to put it as Jones does, “within the material spaces of a city are these immaterial traces of something else.” Along the same lines, Jones distinguishes between a vertical and a horizontal history: on the one hand, she explains, “there is the history that seems to be unfolding and moving forward,” while on the other hand there is a “plunging down into the interiority of the place, into its lost history.” This merging together of time and space, of history and geography is an inherent attribute of cosmopolitanism as it finds an echo in Jones’s novel Five Bells, which takes place on a single day in cosmopolitan Sydney and draws together four characters with their different national backgrounds, haunting histories and memories, all converging on Circular Quay, an Aboriginal site also marked as the place where Captain Cook first set foot. Focusing on the characters’ migrant perceptions of this historical and iconic site, my paper will seek to investigate how Jones draws on the trope of temporal and spatial inheritance in Five Bells to offer “ethical understanding” as an alternative to today’s embattled conception of Australian national identity. [less ▲]

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See detailSynthèse du débat politique. Journée de réflexion au Sénat de Belgique: «Démocratie représentative : vers la fin d’un modèle ? Diagnostic et remèdes»
Verjans, Pierre ULg

in Compte-rendu du Sénat de Belgique (2015, October 01)

Les réflexions des responsables politiques en réaction aux interventions des scientifiques peuvent être interprétées en fonction de grille d'analyse de science politique, notamment celle d'Amartya Sen et ... [more ▼]

Les réflexions des responsables politiques en réaction aux interventions des scientifiques peuvent être interprétées en fonction de grille d'analyse de science politique, notamment celle d'Amartya Sen et celle de Bernard Manin. [less ▲]

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See detailDGTs, a complementary tool towards more efficient biomonitoring practices
Richir, Jonathan ULg; Lepoint, Gilles ULg; Donnay, Annick et al

Conference (2015, October 01)

Among the diversity of contaminants, trace elements (TEs) remain of concern because of their persistence, their ability to accumulate in biota and their toxicity. The direct measurement of their dissolved ... [more ▼]

Among the diversity of contaminants, trace elements (TEs) remain of concern because of their persistence, their ability to accumulate in biota and their toxicity. The direct measurement of their dissolved concentrations only gives punctual and fluctuating information, and often remains below detection limits of analytical methods. The more appropriate use of sentinel organisms, or bioindicators, to monitor TEs has thus often been preferred in environmental surveys. The introduction of the diffusive gradients in thin films (DGTs) technique has however participated to progressively change this binary view - bioindicator vs water - of the coastal monitoring of TEs, and DGTs rapidly became a relevant complementary tool to bioindicators, has illustrated below. In the framework of the STARECAPMED project, the ecology and the ecotoxicology of TEs were studied in the seagrass Posidonia oceanica (L.) Delile and the mussel Mytilus galloprovincialis Lamarck, 1819. DGTs (free- and pore-water probes) were deployed before sampling of organisms. TEs were also analyzed in suspended matter (dissolved and suspended-particulate TE speciation). Studies were performed in the Calvi Bay (Corsica, France), northwestern Mediterranean. TE concentrations in organisms and suspended matter or in DGT resins were measured by DRC-ICP-MS after HNO3/H202 mineralization or after a 24h elution in HNO3 1M, respectively. (1) TE bioaccumulation was first seasonally studied in P. oceanica over 3 years. Dissolved TE concentrations monitored with DGTs were low to very low. TE bioaccumulation dynamics in P. oceanica could thus be linked to the natural physiological cycle of the plant, in clean environmental conditions. (2) To complement that field survey, isolated seagrasses were in situ contaminated with TEs at environmental relevant concentrations. Through the use of DGTs, TE uptake kinetics were modelled for seagrasses exposed to know bioavailable concentrations of contaminants, as were loss kinetics during the following depuration phase. The TE sequestration ability of a healthy P. oceanica meadow facing sudden trace metal contamination events could also be quantified. (3) The deployment of pore-water DGT probes in bare-sand or seagrass colonized sediments further showed that, through its stabilizing function of the seabed, P. oceanica maintained higher TE levels in the pore-water. P. oceanica meadows thus offer a significant “depuration-filtering” ecological service along highly anthropized Mediterranean coasts. M. galloprovincialis are widely used in large spatial scale coastal monitoring surveys. (4) The deployment of caged mussels together with DGTs showed that the little contaminated water body of the Calvi Bay was relatively homogenous. It also allowed to calculate TE bioaccumulation towards mussels in reference conditions, and to compare it to native mussel populations. (5) Finally, during a 5 months mussel caging survey, mussels and suspended matter were collected weekly to monthly, such as were deployed DGTs. The physiological status of mussels, the speciation of TEs between their dissolved and suspended-particulate phases, and their relative influence on TE bioaccumulation dynamics in mussels were investigated. In conclusion, these case studies properly demonstrate how DGT probes can be used as a relevant and complementary tool to bioindicators. Their concomitant use should therefore be privileged in monitoring surveys. [less ▲]

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See detailTranscriptionally active HPV infection in the cervical squamo-columnar junction
Herfs, Michael ULg

Conference (2015, October 01)

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See detailComment décrire la musique expérimentale ? Le cas de Vital Weekly
Claisse, Frédéric ULg

Conference (2015, October 01)

Publiée de manière interrompue sous forme de courrier hebdomadaire depuis 1995, le magazine Vital Weekly est un observateur privilégié de vingt ans d’évolution dans le domaine des musiques expérimentales ... [more ▼]

Publiée de manière interrompue sous forme de courrier hebdomadaire depuis 1995, le magazine Vital Weekly est un observateur privilégié de vingt ans d’évolution dans le domaine des musiques expérimentales. La communication revient sur ce corpus de 1001 numéros, qui voit les chroniqueurs progressivement inventer une forme de critique musicale radicale, gratuite et libre d’accès, sans prétention stylistique ou journalistique, visant l’informativité avant tout, à destination d’une communauté de lecteurs dont beaucoup sont eux-mêmes producteurs ou musiciens. Le magazine illustre la situation hybride des musiques expérimentales, appellation commode et fourre-tout pour des pratiques musicales extrêmement diversifiées, qui doivent autant aux traditions « savantes » du XXe siècle (field recordings, musique concrète, musiques électro-acoustiques, poésie sonore, …) qu’à l’esprit Do-It-Yourself et à l’esthétique industrielle de la cassette culture ayant émergé au tournant des années 1970-1980. D’inspiration pragmatique, l’analyse sociologique présentée ici prend au sérieux l’épreuve perceptive que représente pour le chroniqueur la rencontre avec un matériau sonore qui défie le jugement esthétique. Exemples à l’appui, il s’agit d’expliciter les « prises » de la critique sous contrainte de descriptivité : quels sont les repères conventionnels sur lesquels s’appuyer pour situer l’objet musical dans un espace structuré (paratexte, épitexte, descripteurs de genre, références intertextuelles) ? quels sont les registres (étrangeté, malaise, onirisme, puissance, intimité, présence à soi, matérialité et textures) qui permettent de transmettre au lecteur l’expérience sensible d’un face-à-face avec un objet sonore bouleversant ? [less ▲]

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See detailSofosbuvir in combination with simeprevir +/- ribavirin in genotype 4 hepatitis C patients with advanced fibrosis or cirrhosis: a real-life experience from Belgium
Moreno, C; Lasser, L; DELWAIDE, Jean ULg et al

in Hepatology (Baltimore, Md.) (2015, October), 62(1), 746

Background: All-oral, interferon-free regimens that combine direct-acting antiviral drugs have significantly advanced the treatment of hepatitis C (HCV), especially for genotype 1(G1) patients. However ... [more ▼]

Background: All-oral, interferon-free regimens that combine direct-acting antiviral drugs have significantly advanced the treatment of hepatitis C (HCV), especially for genotype 1(G1) patients. However, efficacy and safety data of interferon-free regimens in HCV genotype 4 (G4) patients are scarce. In Belgium, Sofosbuvir (SOF) and Simeprevir (SMV) treatment is available since January 2015 for G4 patients with advanced fibrosis (F3-F4 METAVIR) for 12 weeks. Methods: analysis of HCV G4 patients receiving SOF and SMV treatment in Belgium. The aim of the study was to evaluate the safety and efficacy of the treatment. Results: 73 G4 patients were enrolled in this data collection including 32 (43.8%) patients with severe fibrosis F3 and 41(56.2%) cirrhotic patients. The study population comprised 58.9% male, 77.8% treatment experienced patients. Median age was 59 [51-66] years and 5 patients were HCV/HIV co-infected. 24 patients received the treatment associated with ribavirin, 11/32 (34.37%) of patients with advanced fibrosis and 13/41 (31.71%) of cirrhotic patients. In cirrhotic patients, median MELD and Child-Pugh score were 9 [7-12.5] and 5 [5-6], 46.2% had platelet below 100.000/mm and 28.6% had albumin below 35 g/L. W4 HCV RNA was undetectable in 31.25% (15/48). 9 of the 15 patients with undetectable W4 HCV RNA received RBV. At W12, 100% (23/23) had HCV RNA below the limit of quantification, with 6/23 still detectable. All SVR12 data will be available at the time of presentation. No patient experienced serious adverse event. Conclusions: these preliminary results in difficult-to-treat G4 HCV patients show that SOF/SIM +/- RBV treatment is safe and seems promising, in line with that was observed in G1 HCV patients. [less ▲]

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See detailHyperthyroïdie sur maladie de Basedow survenant après une hypothyroïdie de Hashimoto : étude clinique et biologique sur 10 cas
Maiga, Ibrahima ULg; BETEA, Daniela ULg; Beckers, Albert ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailEtude et prévalence des troubles neuroendocriniens dans une série de 65 patients avec dommages cérébraux post-traumatiques (TBI) recrutés à partir de la médecine d'expertise
VALDES SOCIN, Hernan Gonzalo ULg; Potorac, J; Matagne et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailMPLS Under the Microscope: Revealing Actual Transit Path Diversity
Vanaubel, Yves ULg; Mérindol, Pascal; Pansiot, Jean-Jacques et al

in ACM Internet Measurement Conference (2015, October)

Traffic Engineering (TE) is one of the keys for improving packet forwarding in the Internet. It allows IP network operators to finely tune their forwarding paths according to various customer needs. One ... [more ▼]

Traffic Engineering (TE) is one of the keys for improving packet forwarding in the Internet. It allows IP network operators to finely tune their forwarding paths according to various customer needs. One of the most popular tool available today for optimizing the use of networking resources is MPLS. On the one hand, operators may use MPLS and label distribution mechanisms such as RSVP-TE in conjunction with BGP to define multiple transit paths (for a given edge pair) verifying different constraints on their network. On the other hand, when operators simply enable LDP for distributing MPLS labels in order to improve the scalability of their network, another kind of path diversity may appear thanks to the ECMP feature of IGP routing. In this paper, using an MPLS labels analysis, we demonstrate that it is possible to better understand the transit path diversity deployed within a given ISP. More specifically, we introduce the Label Pattern Recognition (LPR) algorithm, a method for analyzing traceroute data including MPLS information. LPR reveals the actual usage of MPLS according to the inferred label distribution protocol and is able to make the distinction between ECMP and TE multi-path forwarding. Based on an extensive and longitudinal traceroute dataset obtained from CAIDA, we apply LPR and find that each ISP behavior is really specific in regard to its MPLS usage. In particular, we are able to observe independently for each ISP the MPLS path diversity and usage, and its evolution over time. Globally speaking, the main outcomes of our study are that (i) the usage of MPLS has been increasing over the the last five years with basic encapsulation being predominant, (ii) path diversity is mainly provided thanks to ECMP and LDP, and, (iii), TE using MPLS is as common as MPLS without path diversity. [less ▲]

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See detailStudy of the interaction between the MtgA and inhibitory compounds
Dahmane, Ismahene ULg

Poster (2015, October)

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See detailIs the Darwin´s “Abominable Mystery” still a mystery?
Cascales-Miñana, Borja ULg; Cleal, Chris J.; Gerrienne, Philippe ULg

in Proceedings of the XXXI Annual Meeting of the Spanish Society of Palaeontology (abstract book) (2015, October)

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See detailEpidemiological aspects and genotypic characterization of T.violaceum strains collected during a Belgian National survey on anthropophilic tinea
SACHELI, Rosalie ULg; Dekkers, Charlotte; GRAIDE, Hélène ULg et al

in Mycoses (2015, October), 58(Supplement 4), 189

Objectives The last two years, clinical cases of tinea capitis caused by Trichophyton violaceum (T. violaceum), have been identified in Belgium. To better understand the emergence of this species in the ... [more ▼]

Objectives The last two years, clinical cases of tinea capitis caused by Trichophyton violaceum (T. violaceum), have been identified in Belgium. To better understand the emergence of this species in the population, the Belgian National Reference Center (NRC Liège) launched a one-year national survey in 2013. Epidemiological aspects and genotypic characterization of the strains were included. Methods The study was conducted from March 2013 up to February 2014. All Belgian laboratories were asked to send M. audouinii and T. violaceum strains isolated from hair to the NRC with a form to fill in including epidemiological data. The fungal strains were identified by microscopy or ITS sequencing in case of doubtful identification. The genotypic analysis was performed by the DiversiLab® system (bioMérieux) for DNA fingerprinting and analysis. Epidemiological data were analyzed with the help of a biostatistician. Results Amongst the collected isolates, 23 strains were confirmed as T.violaceum (results concerning the 116 M. audouinii strains have already been reported). Analysis of the epidemiological characteristics of the infected population shows that the main age category concerns 0-4 year-old children (n=9, 39,1%) with a sex-ratio M/F of 1.875. Data concerning the geographic origin of the family were present in 82,6% of the cases and reveal that patients were mainly of Ethiopian origin (n=8, 57,9% of known cases). One patient was also from Burundi showing that T. violaceum strains probably circulate mainly in East Africa. The genotypic analysis led to the distinction of 2 variants of T. violaceum. The major group was composed of 17 strains which were mainly collected in the North of Belgium and included also the reference strain (18/23, 83,3%). The other group (6 strains) was close to the major group but the analysis of the spectral superposition showed some differences between these two groups, defining two distinct variants of T. violaceum in the Belgian population. This second variant was mainly recovered from South Belgium (5/6, 83,3%). No correlation could be made between the genotypic group and a particular ethnical origin as Ethiopian subjects were found in both groups. Conclusion The DiversiLab® system proved to be an efficient method to investigate the molecular epidemiology of dermatophytes infections as reported previously for M. audouinii. These results show that two distinct isolates co-exist in Belgium providing evidence of genetic heterogeneity and a possible spread of one genotypic variant in a restricted geographic area or the co-existence of two variants circulating in different African communities. However, no clear correlation could be established between the appartenance to a group and epidemiological factors, such as age or ethnical origin. [less ▲]

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See detailAnthropogenic particles in stomachs of anchovies (Engraulis encrasicolus) related to gill rakers morphology
Collard, France ULg; Das, Krishna ULg; Gilbert, Bernard ULg et al

in Proceedings of In the Wake of Plastics, Venice, October 13-15, 2015 (2015, October)

Anthropogenic debris (AB) contaminate oceans and affect marine organisms in several ways. Plastic production is constantly increasing and it is estimated that 10% of this production end in the seas. As a ... [more ▼]

Anthropogenic debris (AB) contaminate oceans and affect marine organisms in several ways. Plastic production is constantly increasing and it is estimated that 10% of this production end in the seas. As a consequence, plastic is considered as an emerging contaminant and ingestions by organisms are increasingly reported. Microdebris (< 5mm) are available for a high range of organisms, including planktivorous fish, such as the European anchovy (Engraulis encrasicolus). Planktivorous fish have a particular gill basket, with long and tight gill rakers, related to their diet. Upon these gill rakers, small structures called denticles are present. These gill rakers act as a net to trap organic particles and AB. The aim of our study was to correlate sizes of AB ingested with the mesh constituted by the gill rakers and associated structures. Fifteen stomach contents were analyzed by Raman spectroscopy and particles were measured. Five gill arches were observed with a scanning electron microscope. Cellulose fibers and microplastics were the most AB ingested. Comparing to other Clupeiformes (pilchard and Atlantic herring), anchovies have more denticles on each gill rakers (personal data). AB ingestion by fish is poorly studied and impacts of AB are not much understood. Clupeiformes play a major role in marine ecosystems and is the most consumed order by humans. As the branchial basket constitutes a food selective apparatus, more morphological studies dealing with AB ingestion on Clupeiformes are needed. [less ▲]

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See detailCounseling Program For Caregivers Of People With Alzheimer's Disease: A Case Study
Clesse, Audrey ULg; Adam, Stéphane ULg

Poster (2015, October)

It is widely recognized that living day to day with a family member with Alzheimer's disease is a difficult situation for the relatives. Burden generated by this disease can lead to psychological and ... [more ▼]

It is widely recognized that living day to day with a family member with Alzheimer's disease is a difficult situation for the relatives. Burden generated by this disease can lead to psychological and physical exhaustion for the caregiver, called burnout. Several health studies have shown that caregivers are a population at risk, particularly in terms of depressive symptoms (Covinsky et al., 2003), psychological distress (Pinquart and Sörensen, 2003) or health problems (Schulz et al., 1997). They also present a higher risk of mortality than noncaregivers (Schulz and Beach, 1999). Given these results, we understand the major interest of establishing support program to offer therapeutic monitoring for people caring for a relative with dementia. We present Mrs C.G’s case study, who followed the counselling program developed by Adam et al. (2009). This program aims to meet the specific demands of the caregiver by providing informative elements about the disease, relevant advice based on cognitive functioning through the specific profile of the patient and real daily challenges experienced by the caregiver. The “stress management approach” proposed by Zarit et al. (1987) induces the use of coping strategies focused on problem solving. The comparison between pre and post-intervention brings us positive elements, particularly in enhancement of the caregiver’s quality of life, of his sense of competence and efficiency in managing the disease on a daily basis. About burnout, which was the primary focus this intervention, we find that emotional exhaustion tends to decrease during the counselling sessions. A particularly important finding relates to family changes made throughout the therapy, questioning the organization of family dynamics. These positive results show the importance of developing support programs for caregivers adapted to their needs. Moreover, training therapists for this purpose seems essential because it requires a comprehensive and holistic clinical approach, given the neuropsychological, cognitive behavioural and systemic components involved. [less ▲]

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See detailSociology of literature and sociocriticism
Saint-Amand, Denis ULg

Conference (2015, October)

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See detailUne forme compliquée d'hypercalcémie hypocalciurique familiale
Potorac, Iulia ULg; BETEA, Daniela ULg; MALAISE, Olivier ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailHypogonadisme hypogonadotrope normosmique familial : identification d'une nouvelle mutation c.1664-2A> T du gène FGFR1
VALDES SOCIN, Hernan Gonzalo ULg; Pintiaux, Axelle ULg; LIBIOULLE, Cécile ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailBelgian wildlife as potential zoonotic reservoir of hepatitis E virus
Thiry, Damien ULg

Conference (2015, October)

Hepatitis E is an acute human liver disease in healthy individuals but may become chronic. It is caused by the hepatitis E virus (HEV) and can have a zoonotic origin. In this study, 383 sera from wild ... [more ▼]

Hepatitis E is an acute human liver disease in healthy individuals but may become chronic. It is caused by the hepatitis E virus (HEV) and can have a zoonotic origin. In this study, 383 sera from wild boars were selected for serology; for virology, 69 sera and 61 livers from young wild boars were used. A total of 189 and 235 sera of respectively red and roe deer were collected for serological analysis. For virology, 84 and 68 sera and 29 and 27 livers from respectively red and roe deer were sampled. An apparent seroprevalence of 34% was found in wild boars, 1% in red deer and 3% in roe deer. In order to assess the ELISA screening prevalence, Western blot (WB) analyses and a ROC curve analysis were performed. Different scenarios with varying ELISA specificities relative to WB were analysed. In wild boar, seroprevalence remained high whatever the scenario; 4 out of 69 sera and 4 out of 61 livers were detected as positive for HEV RNA. All sequences obtained from sera belonged to genotype HEV-3. HEV RNA, belonging to genotype HEV-3, was detected in one red deer liver. Wild boar can be considered as a host reservoir of the virus in Belgium. However, the low prevalence in deer makes these species an unlikely reservoir. This evidence needs further investigation in order to determine in which situation deer can serve as reservoir and raise the question of the dynamics of HEV infection between wild fauna, domestic pigs and humans. [less ▲]

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See detailSILURIAN – DEVONIAN OF THE ORIENTAL ALGERIAN SAHARA: implication of new field data from Tassili n'Ajjer outcrops and Berkine Basin (SE, Algeria) for shale gas exploration.
Djouder, Hocine ULg; Boulvain, Frédéric ULg; Da Silva, Anne-Christine ULg et al

in EPC'2015 THE THIRTEENTH TUNISIAN PETROLEUM EXPLORATION & PRODUCTION CONFERENCE (2015, October)

The Silurian – Devonian succession have been deposited in wide sags and sub-basins in a cratonic setting, along the northwestern passive margin of the Gondwana during the opening of the proto-Tethyan ... [more ▼]

The Silurian – Devonian succession have been deposited in wide sags and sub-basins in a cratonic setting, along the northwestern passive margin of the Gondwana during the opening of the proto-Tethyan ocean. During this Siluro-Devonian Period, a high subsidence occurs stacked sediment bodies and organic-rich shales were deposited in many places that respectively form important hydrocarbon reservoirs and source rocks throughout North Africa basins and Arabia (Boot et al., 1998 ; Lüning et al., 2000), which lead Algeria to hold the fourth position in terms of the estimates of technically recoverable shale oil and shale gas resources, based on major basin assessment in the world (EIA, 2013). In the prolific Illizi and Berkine basins (western Ghadames, Algeria) a basin-wide approach is needed, especially with the new “shale gas and shale oil” frontier in the upcoming years, in order to capture regional trends and re-assessment on organic-rich (‘hot’) shale unites which in smaller-scale industrial studies are overlooked. Berkine Basin covers nearly 102.000 km2. This basin has been a thick sedimentary series of 7000 m corresponding to complex reservoirs but also black shales of the basal Silurian and Frasnian respectively major and secondary source rock systems. Wireline-logs from more than 146 (Berkine – Illizi Basins) Algerian petroleum exploration wells have been studies (Djouder et al., 2012; Djouder et al., 2014), and recently 03 months extensive field study of outcrops of the Siluro-Devonian sediments was carried out at the south margin (SE, Tassili n’Ajjer) of the basin. The following analysis incorporates biostratigraphic, ichnological, sedimentological and high resolution stratigraphic data, which provides a framework evolution from offshore to deltaic deposition for the Silurian then fluvial to normal-marine depositional conditions for the Devonian. A total of 06 short-term, third-order sequences can be identified for the Silurian deposits: (i) 'Hot Shale' Oued Imihrou Formation, organic-rich shales with carbonates nodules (Si-1); (ii) above is the Atafaïtafa Formation 500 to 650 m thick with HCS, gutter casts and Cruziana Ichnofacies (Si-2, Si-3); (iii) then overlaid by coarsening-shallowing-upward units. These sequences (Si-4, Si-5 & Si-6) with Storm-wave dominated and Skolithos Ichnofacies are interpreted to reflect deltaic origin. This delta is the result of a significant sea-level drop during the Upper Silurian (Beuf et al, 1971) but also from the high sedimentation rates prograding northwards (Eschard et al., 2005). Devonian deposit also can be divided into fourth third-order sequences (Dev-1 to 4), by the same previous analysis. The base of the cycle is the Caledonian unconformity linked to a tectonic event which affected most of the Gondwanan margin at the Silurian – Devonian boundary and a major relative sea-level fall (Eschard et al., 2005). Previous sequences defined from Tassili n’Ajjer outcrops are well recognized at the basin-scale (Berkine Basin) and can be correlated in the subsurface of the Illizi – Berkine basins (Djouder et al., 2012). Finally, the full depositional cycle for the Silurian – Devonian is reached and capped by the Frasnian maximum flooding surface, with black shales across North Africa (Algeria, western Libya and southern Tunisia) and which are also developed in many parts of the world (Lüning et al., 2003). [less ▲]

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See detailLaparoscopic management of bladder endometriosis
BRICHANT, Géraldine ULg; NICOLAS, Hubert; NISOLLE, Michelle ULg

Conference (2015, October)

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See detailPlankton ecosystem response to the decadal variation of winter intensity in the Mediterranean Sea : a long-term study (1979-2014)
Goffart, Anne ULg; Collignon, Amandine ULg; Hecq, Jean-Henri ULg et al

Poster (2015, October)

In the Mediterranean Sea, several studies with distinct data sets indicate that the pelagic ecosystem underwent periods of change in the late 1980s and in the early 2000s. Here we used a unique long-term ... [more ▼]

In the Mediterranean Sea, several studies with distinct data sets indicate that the pelagic ecosystem underwent periods of change in the late 1980s and in the early 2000s. Here we used a unique long-term time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) from 1979 and 2014 to explore the synchrony between changes in environmental conditions and phyto- and zooplankton dynamics. We identified an almost decadal, long-term variability in winter intensity, with three distinct periods: the 1980s (1979-1988), the 1990s (1989-1998) and the 2000s (1999-2014), which were characterized by moderate, mild and highly variable winters, respectively. We pointed out how the decadal changes in winter intensity affected (i) the duration and intensity of phyto- and zooplankton blooms, (ii) the mean yearly biomasses, and (iii) the nature of the assemblages. High phyto- and zooplankton biomasses were observed in years characterized by moderate and severe winters, and low phyto- and zooplankton abundances were recorded in years with mild winters. Moderate/severe and mild winters were favorable for diatoms and gelatinous zooplankton, respectively. Focusing on meroplanktonic species, we explored ecological consequences of decadal variations observed in the Bay of Calvi for resource management. We highlighted parallelisms with other European seas. [less ▲]

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See detailValorisation de la biomasse pour des applications vers des marchés de niche
Richel, Aurore ULg

Conference (2015, October)

Dans le contexte économique actuel de notre société, il est reconnu que des alternatives et des compléments à la pétrochimie devront être développés dans un futur proche. L’une des solutions possibles ... [more ▼]

Dans le contexte économique actuel de notre société, il est reconnu que des alternatives et des compléments à la pétrochimie devront être développés dans un futur proche. L’une des solutions possibles réside dans le développement de procédés permettant de substituer les actuels produits pétro-sourcés par de nouveaux matériaux bio-basés issus de la biomasse. Sur base de ce constat, Gembloux Agro-Bio Tech et son laboratoire de Chimie Biologique Industrielle se positionnent sur cette thématique en abordant les aspects technico-économiques de transformation du végétal en une gamme de produits à haute valeur ajoutée à destination de divers secteurs applicatifs tels que les matériaux, le cosmétique, le pharmaceutique, etc. L'importance de l'agronomie et des techniques agricoles, combinée à une gestion appropriée des déchets en circuits courts, sont deux piliers discutés dans ce exposé et illustrés au travers de divers exemples stratégiques. [less ▲]

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See detailPlankton ecosystem response to the decadal variation of winter intensity in the Mediterranean Sea : a long-term study (1979-2014)
Goffart, Anne ULg; Collignon, Amandine ULg; Hecq, Jean-Henri ULg et al

Conference (2015, October)

In the Mediterranean Sea, several studies with distinct data sets indicate that the pelagic ecosystem underwent periods of change in the late 1980s and in the early 2000s. Here we used a unique long-term ... [more ▼]

In the Mediterranean Sea, several studies with distinct data sets indicate that the pelagic ecosystem underwent periods of change in the late 1980s and in the early 2000s. Here we used a unique long-term time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) from 1979 and 2014 to explore the synchrony between changes in environmental conditions and phyto- and zooplankton dynamics. We identified an almost decadal, long-term variability in winter intensity, with three distinct periods: the 1980s (1979-1988), the 1990s (1989-1998) and the 2000s (1999-2014), which were characterized by moderate, mild and highly variable winters, respectively. We pointed out how the decadal changes in winter intensity affected (i) the duration and intensity of phyto- and zooplankton blooms, (ii) the mean yearly biomasses, and (iii) the nature of the assemblages. High phyto- and zooplankton biomasses were observed in years characterized by moderate and severe winters, and low phyto- and zooplankton abundances were recorded in years with mild winters. Moderate/severe and mild winters were favorable for diatoms and gelatinous zooplankton, respectively. Focusing on meroplanktonic species, we explored ecological consequences of decadal variations observed in the Bay of Calvi for resource management. We highlighted parallelisms with other European seas. [less ▲]

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See detailValidation of the DermaGenius Nail plus multiplex assay, a new commercial PCR assay developed for the detection and identification of dermatophyte and Candida in nails
Hayette, Marie-Pierre ULg; GRAIDE, Hélène ULg; ADJETEY BAHUN, Akolé ULg et al

in Mycoses (2015, October), 58(suppl 4), 223

Objectives Superficial dermatophytosis is the most common fungal infection in humans. Diagnosis of dermatophytosis is currently based on microscopy or histology associated with culture on specific agar ... [more ▼]

Objectives Superficial dermatophytosis is the most common fungal infection in humans. Diagnosis of dermatophytosis is currently based on microscopy or histology associated with culture on specific agar media. However, direct microscopy lacks specificity and culturing has a long turn-around-time of 2-4 weeks. These limitations can be prevented by the use of molecular diagnostics. The DermaGenius (DG) multiplex kit (PathoNostics, The Netherlands) is a new commercial realtime-PCR kit, which can differentiate various dermatophytes species including the nail pathogens T. rubrum, T. mentagrophytes, T. interdigitale and 2 Candida species (C. albicans and C. parapsilosis). This study aimed at the validation of the kit on nails clippings. Results were compared with histology and culture data. Methods A set of 76 nail clippings was collected from 76 patients attending the dermatology consultation at the University Hospital of Liege on suspicion of onychomycosis. All nails were divided in three pieces for histology, culture and the PCR multiplex assay. Histologic preparations were stained with PAS staining. Cultures were performed on 2 different Sabouraud agar medium slants (bioMérieux). The DNA extraction protocol used a proteinase K pre-treatment followed by an automated DNA-extraction (EasyMag, bioMérieux). An Internal Control (IC) was included to monitor for PCR inhibition or manual errors. The realtime-PCR amplification was performed with the DG kit on a Rotor-Gene Q instrument (Qiagen) by using quantitative amplification and melting curve analysis. Results In total, 35 of 76 cases (46%) were classified as confirmed onychomycosis based on positive microscopy (M+) with or without positive culture (C+) or just by positive culture of a confirmed pathogen. Based on negative microscopy (M-) and negative culture of a confirmed pathogen, 41 cases (54%) were reported as non-fungal onychodystrophy. Agreement between DermaGenius (DG) and culture was found in 52% of the cases while 86% agreement was reported when comparing positive DG with confirmed onychomycosis. Three positive cultures (microscopy negative) were not detected by DG (2 T. rubrum, 1 C. albicans). However, DG could detect 7 additional infections (9%). Eleven discrepancies DG+/C+ were determined which could be positively confirmed in favour of DG result by ITS sequence analysis. Most discrepancies could be explained by fungal/yeast species overgrowing the agar slant, including species of Candida, Fusarium, Trichosporon, which were not considered as the source of infection. Conclusion The DermaGenius Nail plus multiplex was able to detect the most prevalent pathogenic dermatophytes species in clinical nail specimens and proved to be more sensitive and specific than culture and direct microscopy. The DNA extraction procedure has been shown to work efficiently in diagnostics which enables the physician in charge of the patient to start a dedicated treatment rapidly. [less ▲]

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See detailSyndrome thyrogastrique autoimmun (STGA) : la gastrite auto-immune isolée (GAI) et celle associée à Helicobacter (Hp) ont des caractéristiques anatomocliniques différentes
VALDES SOCIN, Hernan Gonzalo ULg; MESUREUR, Thierry ULg; POLUS, Marc ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailGrey-box nonlinear state-space modelling for mechanical vibrations identification
Noël, Jean-Philippe ULg; Schoukens, Johan; Kerschen, Gaëtan ULg

in Proceedings of the 17th IFAC Symposium on System Identification (2015, October)

In the present paper, a flexible and parsimonious model of the vibrations of nonlinear mechanical systems is introduced in the form of state-space equations. It is shown that the nonlinear model terms can ... [more ▼]

In the present paper, a flexible and parsimonious model of the vibrations of nonlinear mechanical systems is introduced in the form of state-space equations. It is shown that the nonlinear model terms can be formed using a limited number of output measurements. A two-step identification procedure is derived for this grey-box model, integrating nonlinear subspace initialisation and maximum likelihood optimisation. The complete procedure is demonstrated on the Silverbox benchmark, which is an electrical mimicry of a single-degree-of-freedom mechanical system with one displacement-dependent nonlinearity. [less ▲]

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See detailAnthocyanin-rich blackcurrant juice induces a redox-sensitive caspase 3-related pro-apoptotic effect in leukemia Jurkat cells: role of delphinidin-3-O-glucoside and delphinidin-3-O-rutinoside
Leon-Gonzalez; Sharif, T; Kayali, A et al

in 7th International Conference on Polyphenols and Health (2015, October)

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See detailTriclosan retardes development of Sheepshead minnow (Cyprinodon variegatus)
Dussenne, Mélanie ULg; Frederich, Bruno ULg; Das, Krishna ULg et al

Conference (2015, October)

The aquatic environment represents the final sink for many chemicals, including bactericidal agents. Among them Triclosan (TCS), with his chemical structure similar to thyroid hormones (THs), may have ... [more ▼]

The aquatic environment represents the final sink for many chemicals, including bactericidal agents. Among them Triclosan (TCS), with his chemical structure similar to thyroid hormones (THs), may have adverse effects on the thyroid system. The study we carried out aims to evaluate the effects of TCS exposure on development of Cyprinodon variegatus, a fish model used in ecotoxicological studies. We investigated the potential effects of TCS on C. variegatus during two key periods; embryonic development and metamorphosis. We exposed eggs and larvae to environmental relevant concentrations. We showed that TCS had no effect on reproduction parameters, such as egg fertility or survival rate of larvae. However, we highlighted the fact that hatching of exposed larvae was delayed of around 6 to 13 hours compared to control embryos. During the larval phase, measurements of THs levels were performed. We showed that TCS affected the typical ontogenic variations of the whole body thyroid hormones concentrations during metamorphosis. As THs are known to control somatic growth and development, we tested the effects of TCS exposure on morphological development. We observed no deformity or malformation, but we revealed a developmental retardation in larvae exposed to TCS, of around 18 to 32 hours. Such a developmental delay had never been highlighted in previous studies on TCS exposed fish. We hypothesize that the disruption of THs homeostasis affects the timing of the start of metamorphosis. As a consequence, exposed larvae showed an extended larval phase compared to the control group. The harmful effects of TCS on physiology and development are a major concern, as marine organisms are constantly exposed to it. Furthermore, strong connections exist between thyroid and reproductive system, which might have deleterious effects on population dynamics. [less ▲]

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See detailTrade secrets: Overlap with restraint of trade, aspects of enforcement - Belgium
Kaesmacher, Dominique; Vanbrabant, Bernard ULg; Thoumsin, Pierre-Yves et al

in AIPPI Yearbook 2014 (2015, October)

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See detailSoil production and hillslope transport in mid-latitudes during the last glacial-interglacial cycle: A combined data and modelling approach in northern Ardennes
Bovy, Benoît ULg; Braun, Jean; Demoulin, Alain ULg

Conference (2015, October)

The relative efficiency of various hillslope processes through Quaternary glacial-interglacial cycles in the mid-latitudes is not well constrained. Based on a unique set of topographic and soil thickness ... [more ▼]

The relative efficiency of various hillslope processes through Quaternary glacial-interglacial cycles in the mid-latitudes is not well constrained. Based on a unique set of topographic and soil thickness data in the Ardennes (Belgium), we combine the new CLICHE model of climate-dependent hillslope evolution with an inversion algorithm in order to get deeper insight into the ways and timing of hillslope dynamics under one such climatic cycle. We simulate the evolution of a synthetic hill reproducing the terrain attribute distributions of the hillslopes of a ~2500 km2 real area under a simple two-stage 120-kyr-long climatic scenario with linear transitions. The inversion method samples a misfit function in the model parameter space, based on estimates of the fit of topographic derivative distributions in classes of soil thickness and of the relative frequencies of the predicted soil thickness classes. Though the inversion results show convergence patterns for several parameters, no unique solution emerges. We obtain five clusters of good fits, whose centroids are taken as acceptable model solutions. Based on the predicted time series of average denudation rate and soil thickness, plus snapshots of the soil distribution at characteristic times, we compare these solutions with independent data not involved in the misfit function and identify the most realistic one. Providing first-order estimates of several parameters that compare well with published data, it shows that denudation rates increase dramatically at both warm-cold and cold-warm transitions when the mean annual temperature passes through the [0, -5°C] range. It also underlines the overwhelming importance of gelifluction in transporting soil and shaping hillslopes. [less ▲]

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See detailDéchéance de nationalité et terrorisme : quelle marge de manoeuvre pour l'Etat?
Wautelet, Patrick ULg

Conference (2015, October)

Cette présentation a pour objet de situer de manière critique les récentes interventions du législateur belge en matière de déchéance de la nationalité belge, en montrant quelles sont les limites ... [more ▼]

Cette présentation a pour objet de situer de manière critique les récentes interventions du législateur belge en matière de déchéance de la nationalité belge, en montrant quelles sont les limites internationales à l'action du législateur national. Le cadre législatif en vigueur en Belgiqe est analysé en particulier à la lumière de l'interdiction de discrimination [less ▲]

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See detailHow T2-weighted signal intensity of GH-secreting adenomas correlates wit response to primary somatostatin analogue therapy in acromegaly
Potorac, Iulia ULg; PETROSSIANS, Patrick ULg; Daly, Adrian ULg et al

in Abstract book - 25th meeting of the Belgian Endocrine Society (2015, October)

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See detailLa participation et ses distorsions: du malentendu aux bénéfices secondaires
Italiano, Patrick ULg

in Bingen, Aline; Pilet, Jean-Benoît (Eds.) L'art de la participation (2015, October)

Les dispositifs participatifs, dans la vie réelle, sont souvent soit verrouillés soit déconnectés de la décision finale sur laquelle ils sont censés porter. Cela peut avoir des effets délétères sur les ... [more ▼]

Les dispositifs participatifs, dans la vie réelle, sont souvent soit verrouillés soit déconnectés de la décision finale sur laquelle ils sont censés porter. Cela peut avoir des effets délétères sur les publics que ces dispositifs voulaient impliquer. Il n'est pas rare que l'on donne le label "participation" à des processus dont la nature est mieux décrite par d'autres concepts. En définitive, c'est probablement dans des dispositifs centrés sur les personnes, et non sur des prises de décisions politiques, que l'exercice participatif est le plus susceptible d'avoir un effet positif univoque. [less ▲]

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See detailPerformance evaluation of mid-IR vortex coronagraphs with centrally obscured segmented pupils
Carlomagno, Brunella ULg; Absil, Olivier ULg; Ruane, Garreth J. et al

Poster (2015, October)

In its original design, the E-ELT/Metis instrument envisages a vortex coronagraph in the mid-IR regime for detection and characterization of exoplanets, with a contrast of 1e-4 at 2 lambda/D (~40 mas in L ... [more ▼]

In its original design, the E-ELT/Metis instrument envisages a vortex coronagraph in the mid-IR regime for detection and characterization of exoplanets, with a contrast of 1e-4 at 2 lambda/D (~40 mas in L band). The AGPM (Annular Groove Phase Mask) is a vortex phase mask with impressive characteristics: small inner working angle, high throughput, achromaticity. A non-perfectly circular pupil and non-flat input wavefront result in a starlight leakage, degrading the performance of the vortex coronagraph. In this work, we present end-to-end performance simulations using Fourier optical propagation to determine the quality of the starlight rejection obtained with an infrared vortex coronagraph. We first analyse the performance facing E-ELT pupil variations (segmentations, central obscuration, spiders, missing segments), then pointing jitter and random adaptive optics residual phase screens are introduced to derive more realistic performance. Finally, more advanced concepts of the infrared vortex coronagraph are presented, in order to compensate for performance degradation. [less ▲]

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See detailSymboliser et conceptualiser, deux facettes indispensables de la pensée mathématique. L'exemple de l'algèbre.
Vlassis, Joëlle; Fagnant, Annick ULg; Demonty, Isabelle ULg

in Actes du congrès EMF 2015. Pluralités culturelles et universalité des mathématiques : enjeux et perspectives pour leur enseignement et leur apprentissage. (2015, October)

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See detailGestationnal trophoblastic diseases
GOFFIN, Frédéric ULg; Seckl, M

Conference (2015, October)

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See detailWhere is the ancient harbour of Utica ? Geoarchaeology and palaeoenvironment of the Medjerda delta (Tunisia)
Pleuger, Elisa ULg; Abichou, Hakim; Gadhoum, Ahmed et al

Poster (2015, October)

Ancient authors mention Utica as a maritime and port city and estimate its origin around the 11th c. BC. However, in the present state of research, no archaeological evidence is earlier than the 9th c. BC ... [more ▼]

Ancient authors mention Utica as a maritime and port city and estimate its origin around the 11th c. BC. However, in the present state of research, no archaeological evidence is earlier than the 9th c. BC, and the location of the Phoenician and Roman port infrastructures remains unknown. Today, the ancient city is located on a promontory in the heart of the Medjerda delta, 10 km inland. This project proposes an interdisciplinary effort to understand the Medjerda delta landscape changes during the Holocene. It starts from an archaeological problem and proposes the contribution of geoarchaeology to the understanding of the relationship between ancient societies and their environment. The fluvial palaeoenvironments and sedimentary processes are studied through the mechanical extraction of cores (15-20 m deep) to reach the early Holocene. Selected sediment samples are then studied in laboratory, using different and complementary approaches. First results permitted to draw an hypothesis of the coastline during Antiquity and to bring out the evidence of an intense sedimentation event post 10th c. BC. The location of port infrastructures will bring initial answers to the question of the foundation of the city. The study of river palaeoenvironments of the Medjerda delta during the Holocene aim at a better understanding of the nature of the settlement, as well as the function of the city of Utica over time. This study will also assess the impact of the ancient city on the environment and understand how the city adapted to the mobility of this Mediterranean delta. Furthermore, the analysis of sedimentary processes causing the filling of the harbour basin will lead to speculation about the causes of the abandonment of the structures and more generally the decline of the city in favor of Carthage. It will also examine whether natural or anthropogenic factors have influenced this deltaic progradation over the centuries. [less ▲]

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See detailOnychomycosis: is it possible to increase the cure rate?
Hayette, Marie-Pierre ULg

in Mycoses (2015, October), 58(suppl 4), 35

Onychomycosis represent about 50% of nails disorders in the world with a very variable prevalence depending of the countries considered. Dermatophytes, non-dermatophyte molds and Candida sp. are the main ... [more ▼]

Onychomycosis represent about 50% of nails disorders in the world with a very variable prevalence depending of the countries considered. Dermatophytes, non-dermatophyte molds and Candida sp. are the main causing agents. A rapid and accurate diagnosis is essential in order to give an adequate treatment to the patient. Generally, a combination of microscopy and culture is used for laboratory diagnosis. However, microscopy does not always allow the distinction between yeasts or filamentous fungi, culture takes generally about a week before identification and the result is compromised if there is contamination by not relevant fungi. Therefore commercially available PCR-based methods have been developed in order to provide a rapid and accurate identification of dermatophytes and yeasts in nails samples. Combination of microscopy and PCR may provide a rapid and specific diagnosis in 2 working days. However this methodology is still not widely used by laboratories because of the high cost. Furthermore, this technology can detect DNA from dead fungi and therefore is not suitable for assessment of treatment efficacy. Onychomycosis therapy depends on different factors such as the causative agent, the number of nails and degree of nail involvement, the type of onychomycosis, potential drug interactions or drug intolerance and a failure to previous treatments. Oral and topical antifungals are mostly used separately or in combination. Oral therapy includes azoles (itraconazole, fluconazole) and/or allylamine (terbinafin), this latter being the most frequently prescribed antifungal for treatment of onychomycosis in North America and Europe. Topical amorolfine and ciclopirox formulations can be used alone in mild cases or in case of intolerance to oral antifungals. However, one of the biggest problems of therapy for onychomycosis is the high frequency of relapse which concerns about 20 to 40% of the patients treated by oral antifungals. Different strategies have been developed to overcome this problem amongst which are: optimization of the dosing regimens (continuous vs pulse therapy) or therapy duration, combination therapy (nail debridement + antifungals, oral + topical drugs, 2 oral drugs), improving drug delivery (use of physical or chemical enhancers, and modification of the pharmacological formulation for increasing drug uptake). Some strategies such as combination therapy (oral + topical) have demonstrated enhanced efficacy and should be recommended in case of poor efficacy of the initial treatment or in case of extended infection. Prophylactic topical therapy implemented after completion of oral treatment has been shown to delay relapse. Preventive measures such as treatment of concurrent tinea pedis and/or infected family members and regular cleaning of bathroom and shower floors can help to reduce the risk of reinfection particularly when a dermatophyte is the causative agent. In conclusion, treatment for onychomycosis is associated with frequent relapse. Consequently, follow-up is mandatory and combination therapy can be necessary in case of relapse or resistance to treatment. Patients should also be aware of the preventive hygiene measures to apply in order to decrease the risk of reinfection. New strategies improving treatment efficacy are promising but their efficacy have still to be demonstrated in comparative clinical trials before their implementation in therapy. [less ▲]

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See detailUne lésion sellaire d'évolution hautement fluctuante
BETEA, Daniela ULg; Potorac, Iulia ULg; BONNEVILLE, Jean-François ULg et al

in Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailNouvelle mutation du Fibroblast Growth Factor Receptor 1 (FGFR1)-cause d'hypogonadisme hypogonadotrope idiopathique normosmique
Potorac, Iulia ULg; Chachati, Anne-Sophie ULg; Debray, François-Guillaume ULg et al

in Abstract book- Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie (2015, October)

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See detailDévelopper l'autorégulation et les compétences en résolution de problèmes : une étude exploratoire en fin d'enseignement primaire
Fagnant, Annick ULg; Jaegers, Doriane ULg

Conference (2015, October)

L’article s’appuie sur une étude exploratoire en fin d'enseignement primaire (grade 6, élèves de 11-12 ans). L’approche d’enseignement/apprentissage mise en place visait conjointement à développer des ... [more ▼]

L’article s’appuie sur une étude exploratoire en fin d'enseignement primaire (grade 6, élèves de 11-12 ans). L’approche d’enseignement/apprentissage mise en place visait conjointement à développer des capacités d’autorégulation et l’apprentissage d’une démarche de résolution de problèmes en favorisant les régulations interactives et, particulièrement, le recours à une grille de co-évaluation. Le dispositif quasi-expérimental de l’étude permet d’apprécier les progrès plus importants des élèves de la classe expérimentale (comparativement à une classe contrôle) en termes de performances mais aussi d’une certaine anticipation et planification de la démarche de résolution. Ils démontrent aussi de meilleures capacités d’autoévaluation. Les entretiens réalisés avec quelques élèves permettent de mettre en évidence la plus-value des différentes formes de régulations interactives mises en place. Enfin, plusieurs éléments permettent également d’émettre l’hypothèse d’un impact positif de l’approche sur les variables affectives et motivationnelles. [less ▲]

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