References of "Scientific congresses and symposiums"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailDecision algorithms for the re-treatment with viscosupplementation in patients suffering from knee osteoarthritis
Henrotin, Yves ULg; Richette, Pascal; Raman, R et al

in Osteoarthritis and Cartilage (2017), 25

Detailed reference viewed: 18 (1 ULg)
See detailPegmatite phosphates: from the field to the lab
Hatert, Frédéric ULg

Conference (2017)

Detailed reference viewed: 5 (1 ULg)
Full Text
See detailVirus Discovery: After the deluge ... ...the framework!!!
Massart, Sébastien ULg

Conference (2017)

Detailed reference viewed: 11 (0 ULg)
Peer Reviewed
See detailUne architecture de frontières : les monastères des annonciades célestes dans les Trois-Evêchés (17e-18e siècles)
Piront, Julie ULg

in Bourdieu, Catherine (Ed.) Vie religieuse féminine dans les Trois-Evêchés : vocations, missions et cadres d'existence (2017)

Les Trois-Evêchés ont été un terrain fertile pour les congrégations féminines aux 16e-18e siècles puisqu'ils ont vu la naissance de projets religieux conjuguée à une installation massive de « nouveaux ... [more ▼]

Les Trois-Evêchés ont été un terrain fertile pour les congrégations féminines aux 16e-18e siècles puisqu'ils ont vu la naissance de projets religieux conjuguée à une installation massive de « nouveaux ordres » nés ou réformés dans le sillage du concile de Trente. Fondées en Italie au début du 17e siècle, les annonciades célestes se sont implantées majoritairement sur la « dorsale catholique ». Au cœur de ce territoire de frontières, les Trois-Évêchés occupent une position géographique, politique et religieuse incontournable. Dans le cadre de cette journée d’études, il s’agira d’interroger les spécificités éventuelles des cinq monastères que les annonciades célestes firent édifier dans les Trois-Évêchés en les comparant à l’ensemble de la production architecturale de l’ordre en Europe aux 17e et 18e siècles. En allant plus loin, nous verrons comment les représentations mentales de ces édifices ont participé à la genèse de l’identité de l’ordre, notamment grâce aux sources écrites et iconographiques qui en témoignent. [less ▲]

Detailed reference viewed: 20 (0 ULg)
Full Text
Peer Reviewed
See detailEffects of the soil pore network architecture on the soil’s physical functionnalities
Smet, Sarah ULg; Beckers, Eléonore ULg; Léonard, Angélique ULg et al

in Geophysical Research Abstracts (2017), 19

Detailed reference viewed: 22 (3 ULg)
Peer Reviewed
See detailImportance of parenteral nutrition in feeding the premature infant
SENTERRE, Thibault ULg

in International Conference for Advancing Nutrition - Neonatology, Brussels (2017)

Detailed reference viewed: 12 (0 ULg)
See detailImmigration, antisemitism and toleration in Western Europe today: the case of Belgium
Martiniello, Marco ULg; Muriel, Sacco

Conference (2017)

Detailed reference viewed: 5 (1 ULg)
Full Text
Peer Reviewed
See detailIN VIVO STUDY OF THE SV2A PROTEIN IN THE KAINIC ACID EPILEPSY RAT MODEL
Serrano Navacerrada, Maria Elisa ULg; Becker, Guillaume ULg; Bahri, Mohamed Ali ULg et al

Poster (2017)

Introduction Epilepsy is one of the commonest neurological disorders [1]. Antiepileptic drugs mainly target the SV2A protein [2] but its actual role is still largely unknown. [18F]UCB-H was developed to ... [more ▼]

Introduction Epilepsy is one of the commonest neurological disorders [1]. Antiepileptic drugs mainly target the SV2A protein [2] but its actual role is still largely unknown. [18F]UCB-H was developed to study in vivo SV2A brain proteins [3, 4]. The present pilot study was undertaken to evaluate for the first time in vivo in rats SV2A expression in the Kaïnic Acid (KA) epilepsy model [5]. Although this model is well studied in mice, few reports were devoted to rats. Imaging-wise, rats are very interesting thanks to a bigger brain size (reduction of the partial volume effect). Methods Three male Sprague-Dawley were used, one injected with saline and two with multiple KA injections (3 x 5mg/kg) [6]. 75 days later, when spontaneous seizures started to appear, microPET (Focus 120 ) was performed under isoflurane anesthesia (2.5-3 % in air) for 1 hour with [18F]UCB-H (41 ± 5 MBq IV tail vein) followed by MRI (9.4T Agilent, anatomical T2). Coregistration was done with PMOD 3.6 software. Data were expressed as SUV and areas under the curve were calculated for the different regions. Results [18F]UCB-H microPET images showed an important reduction (20-30%) for SV2A after KA injections mainly localized in amygdala, hippocampus, lateral parietal association cortex and cingulate cortex. The rest of the brain was globally unchanged. MRI revealed atrophy and inflammation in amygdala and hippocampus. Conclusions These preliminary results obtained in KA treated rats showed that [18F]UCB-H was able to detect important modifications for SV2A in relevant regions for epilepsy and appears as a valuable tool to follow in vivo SV2A through longitudinal studies. KA model in rats deserves for further development and validation as a tool for the study of epilepsy. [less ▲]

Detailed reference viewed: 29 (1 ULg)
Peer Reviewed
See detailProcessus cognitifs et neurobiologiques sous-jacents aux déficits de mémoire épisodique dans la maladie d’Alzheimer
Collette, Fabienne ULg

Conference (2017)

Les troubles de la mémoire épisodique représentent une des caractéristiques majeures et précoces de la maladie d’Alzheimer. Ces difficultés sont classiquement attribuées à des déficits au niveau de ... [more ▼]

Les troubles de la mémoire épisodique représentent une des caractéristiques majeures et précoces de la maladie d’Alzheimer. Ces difficultés sont classiquement attribuées à des déficits au niveau de l’encodage et de la consolidation de l’information, processus dépendant notamment des régions temporales internes (et plus particulièrement de l’hippocampe) qui sont atteintes très tôt dans le décours de la maladie. Un certain nombre de données récentes ont toutefois amené à raffiner cette conceptualisation initiale. Il est en effet progressivement apparu que des processus très spécifiques sous-tendent la performance aux tâches de mémoire épisodique utilisées en clinique pour le diagnostic de la maladie, tels que la capacité à créer des liens associatifs entre les items ou à créer des représentations mnésiques très distinctives, ou encore la capacité à faire appel à des processus auto-référentiels. L’efficacité de ces processus semble par ailleurs affectée de façon relativement sélective par différents processus neuropathologiques tels que l’atrophie de certaines régions hippocampiques, la diminution de l’épaisseur corticale, la déconnexion entre réseaux cérébraux, la charge amyloide, ou même la présence de facteurs plus subjectifs tels qu’une plainte mnésique. Les troubles de mémoire épisodique associés à la maladie d’Alzheimer semblent donc clairement multidéterminés. En lien avec ces données cognitives et neurobiologiques, nous discuterons également brièvement l’intérêt des classifications actuelles des troubles cognitifs associés au vieillissement pour comprendre le fonctionnement mnésique et ses bases cérébrales. [less ▲]

Detailed reference viewed: 58 (1 ULg)
Peer Reviewed
See detailDiplomatie sur le terrain : la première mission diplomatique florentine en territoire mamelouk.
Rizzo, Alessandro ULg

in Culture matérielle et contacts diplomatiques entre l’Occident latin, Byzance et l’Orient islamique (XIe-XVIe siècle). (2017)

Detailed reference viewed: 31 (3 ULg)
Full Text
Peer Reviewed
See detailEnergetic and Environmental Performances of a Domestic Hot Water Condensing Boiler Fired by Wood Pellets
Ngendakumana, Philippe ULg; Gabriele, Fabian; Restivo, Yannick et al

in Energy Procedia (2017)

In order to assess the performances of the domestic heating boilers with a CE mark, a wood pellets fired condensing boiler has been purchased and installed in the Laboratory for tests. The objective of ... [more ▼]

In order to assess the performances of the domestic heating boilers with a CE mark, a wood pellets fired condensing boiler has been purchased and installed in the Laboratory for tests. The objective of the study was not only to check the announced performances, but mainly to investigate the influence of the different parameters affecting the functioning of the boiler, the thermal efficiency and the pollutants (NOx and CO) emission being aimed at. Tests have been performed to study the influence of the cycling frequency of the burner functioning, the overall excess air, the return water temperature, and the output power of the boiler. As announced by the manufacturer, the tested boiler fulfils the requirements of the Blue Angel Label, but the recommended value for the excess air (1.2) can be reduced to a value of about 0.4 without excessive emissions of CO. The boiler could perform better if the ON period of the cycle of the burner is increased even better if the OFF period is suppressed. The NOx are mainly formed from the nitrogen content of the pellets and their emissions can only be reduced by a lower nitrogen content of the pellets than the limit stated in the standard. Random peaks observed in the evolution of CO, the boiler being operating in steady state regime, are attributed to the combustion process of pellets which is a non-continuous process by nature. [less ▲]

Detailed reference viewed: 29 (1 ULg)
Full Text
Peer Reviewed
See detailPlant Oxylipins: Structure-function Relationships
Genva, Manon ULg; Andersson, Mats X.; Nasir, Mehmet Nail ULg et al

Poster (2017)

Detailed reference viewed: 20 (0 ULg)
Full Text
Peer Reviewed
See detailLes tables de discussion : une pratique d’évaluation formative par les pairs mise en place pour des étudiants de Master en Sciences de l’Éducation
Michel, Aurore ULg; Baye, Ariane ULg

in 29e Colloque de l'Admée Europe - L'évaluation : levier pour le développement professionnel et les apprentissages (Axe 4) (2017)

Cette communication exposera une pratique d’évaluation formative mutuelle proposée dans le cadre d’un cours sur les dispositifs pédagogiques de lutte contre le décrochage et l’exclusion adressé aux ... [more ▼]

Cette communication exposera une pratique d’évaluation formative mutuelle proposée dans le cadre d’un cours sur les dispositifs pédagogiques de lutte contre le décrochage et l’exclusion adressé aux étudiants de Master. Cette pratique vise à accompagner les étudiants dans la réalisation d’un travail de groupe ayant pour tâche d’analyser un dispositif pédagogique de lutte contre le décrochage. Pour les aider dans la réalisation, deux moments clés structurent l’accompagnement : une rencontre avec les encadrantes pour discuter et valider la démarche envisagée et des « tables de discussion » centrées sur l’évaluation formative mutuelle du travail collectif à produire (travail dit « intermédiaire » rédigé au plus près de la version finale attendue). L’objectif de ces tables pour chaque groupe est double : permettre de prendre de la distance par rapport à sa propre production écrite et de profiter du regard extérieur apporté par les autres groupes pour enrichir son propre travail. Les lectures d’autres rapports intermédiaires et le feedback apporté par chaque membre de la table de discussion sont en effet autant de nouvelles sources de réflexion. Ces nouveaux apports permettent notamment de clarifier l’attendu par rapport aux critères d’évaluation finaux et de retravailler le contenu (Mottier Lopez, 2015). Concrètement, chaque étudiant est amené à évaluer, par écrit, sur base d’une grille reprenant les critères et indicateurs d’évaluation du travail final, deux à trois travaux intermédiaires. Lors de cette phase de lecture, l’étudiant relève tant les éléments positifs que négatifs identifiés et formule, pour ces derniers, des pistes concrètes d’amélioration. Lors des tables de discussion, le timing est prévu de façon à octroyer à chaque groupe présent un temps égal d’échanges autour des lectures et évaluations formatives réalisées par chaque participant présent. La communication décrira le dispositif d’évaluation formative et présentera les données recueillies auprès des étudiants concernant l’utilité du dispositif. [less ▲]

Detailed reference viewed: 40 (4 ULg)
Peer Reviewed
See detailFeedback effect on children's global metacognitive judgments
Geurten, Marie ULg; Meulemans, Thierry ULg

Poster (2017)

In three experiments, we investigated whether the feedback effect on the accuracy of children’s metacognitive judgments results from an improvement in monitoring processes or the use of the Anchoring-and ... [more ▼]

In three experiments, we investigated whether the feedback effect on the accuracy of children’s metacognitive judgments results from an improvement in monitoring processes or the use of the Anchoring-and-Adjustment heuristic. The purpose of Experiment 1 was to investigate whether 4-, 6-, and 8-year-old children are able to use feedback to increase the accuracy of their memory judgments. To do so, children in three age groups were divided into two experimental conditions (feedback or no feedback). After studying a list of associated words, participants were instructed to predict their future memory performance, and then they were asked to recall as many items as possible. Next, half of the participants were given concrete feedback about the accuracy of their global prediction. Once the feedback was provided, all children were presented with another set of associated word pairs and the procedure was repeated. Our results revealed that children’s predictions were more accurate in the feedback than in the no feedback condition, indicating that getting feedback about the accuracy of their judgments had a positive influence on their subsequent memory predictions. In Experiment 2, we sought to determine whether young children are able to use the Anchoring-and-Adjustment heuristic to guide their global memory predictions. For this purpose, 4-, 6-, and 8-year-old children were divided into three experimental conditions depending on the anchor that was provided (high, low, or no anchor). Data indicated that children’s predictions were higher in the high than in the low anchor condition, suggesting that children in all age groups adjusted their prospective judgment depending on the random anchor they were given. Finally, the primary aim of Experiment 3 was to determine whether the feedback effect can serve as an external anchor for children’s global prospective judgments. To do so, children (aged 4, 6, and 8 years) were presented with two memory tasks that differed in terms of difficulty. Participants were randomly assigned to an anchoring (high, low, or no anchor) and a feedback (feedback or no feedback) condition to obtain a balanced experimental design. Results showed that children in the feedback condition adjusted their predictions toward the feedback, regardless of the task’s difficulty. These findings are consistent with the hypothesis that external information provided by feedback is used as an anchor for judgment. This interpretation is strengthened by the correlation found between the two scores computed to assess participants’ susceptibility to anchoring and feedback effects, which indicates that children who are more sensitive to the anchoring effect are also more sensitive to the feedback effect. [less ▲]

Detailed reference viewed: 33 (2 ULg)
See detailIncidence of MAGED2 on cell cycle after a camptothecin treatment
Trussart, Charlotte ULg; Pirlot, Céline; Piette, Jacques ULg et al

Poster (2017)

Detailed reference viewed: 19 (1 ULg)
Full Text
Peer Reviewed
See detailEffect of moderate increasing exercice on the mechanical balance of the knee joint in young rats
Rahnamay Moshtagh, Parisa; Korthagen, N; Plomp, S et al

in Osteoarthritis and Cartilage (2017), 25

Detailed reference viewed: 8 (1 ULg)
See detailLe plan zonal de sécurité, instrument d'accountability de la police locale ?
Croquet, Alice ULg

in Ficet, Joël; Fallon, Catherine (Eds.) Actes du Colloque de l'ABSP - "Crise de la démocratie et nouveau management public" : Liège, 10-11 avril 2014 (2017)

La contribution propose d'analyser dans quelle mesure l'on peut comprendre le Plan Zonal de Sécurité comme un outil d'accountability des zones de police locale.

Detailed reference viewed: 21 (4 ULg)
Full Text
See detailEarthquake imprints on a lacustrine deltaic system: Example of the Kürk Delta along the East Anatolian Fault (Turkey)
Hubert, Aurelia ULg; El Ouahabi, Meriam ULg; Moreno, David et al

in Geophysical Research Abstracts (2017), 19

Detailed reference viewed: 6 (1 ULg)
Full Text
Peer Reviewed
See detailDurabilité du maraîchage urbain : entre ancrage territorial et trajectoires de mise en œuvre
Plateau, Lou; Maughan, Noémie; Visser, Marjolein et al

Conference (2017)

Detailed reference viewed: 16 (0 ULg)
Full Text
See detailNowate: Waste heat re-use for greener trucks
Lemort, Vincent ULg; Guillaume, Ludovic ULg; Bettoja, Federica et al

Conference (2017)

Detailed reference viewed: 15 (1 ULg)
Full Text
See detailLa Célestine versus Lazarillo: un cas de crossover littéraire
Francois, Jeromine ULg

Conference (2017)

Detailed reference viewed: 14 (3 ULg)
Full Text
See detailNeurobiologische Korrelate von exekutiver Kontrolle im alternden Gehirn
Overhage, Sina; Eickhoff, Simon; Jockwitz, Christiane et al

Poster (2017)

Detailed reference viewed: 41 (1 ULg)
Full Text
Peer Reviewed
See detailRule-based control and optimization of a hybrid solar microgrid for rural electrification and heat supply in sub-Saharan Africa
Altés Buch, Queralt ULg; Orosz, Matthew; Quoilin, Sylvain ULg et al

in Proceedings of the 30th International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems (ECOS) (2017)

This work aims at developing, optimizing and controlling a hybrid solar microgrid for rural electrification and heat supply in sub-Saharan Africa. The considered system includes PV panels, Parabolic ... [more ▼]

This work aims at developing, optimizing and controlling a hybrid solar microgrid for rural electrification and heat supply in sub-Saharan Africa. The considered system includes PV panels, Parabolic Trough Collectors, ORC and LPG generator, as well as battery and thermal energy storage. A special focus is paid to the co-optimization of the thermal and electrical load satisfaction since it can improve the overall energy efficiency of the system. To that end, different sub-component models are developed: - A building model to predict thermal loads of a health clinic in rural communities of Lesotho. - A microgrid model built by interconnecting the subcomponent models. - A rule-based control strategy, dispatching heat and electrical powers of each component to cover the demand while minimizing the fuel consumption. - A particle-swarm optimization of the microgrid under different cost assumptions. For the studied community of Ha Nkau in Lesotho, the determined optimal system infrastructure is composed of PV (66 kW) and batteries (262 kWh), and the optimum control strategy achieves a levelized cost of electricity of 0.203 USD/kWh. Fuel consumption is mainly due to the burner, which supplies most of the thermal load together with CSP (66 m2) and TES (86 kWh). [less ▲]

Detailed reference viewed: 23 (0 ULg)
See detailLa diffusion des Blattmasken dans le bassin Méditerranéen. Entre tradition et innovation
Derwael, Stéphanie ULg

in Actes du colloque "Colloque La diffusion des répertoires décoratifs en Méditerranée antique et médiévale" (2017)

Detailed reference viewed: 17 (0 ULg)
Full Text
See detailCognitive functioning and multimodal neuroimaging interactions in patients with disorders of consciousness
Aubinet, Charlène ULg; Murphy, Lesley; Gosseries, Olivia ULg et al

in Journal of the International Neuropsychological Society (2017)

Detailed reference viewed: 32 (1 ULg)
Peer Reviewed
See detailImpact of vibroseismic underwater sound on the behaviour of baleen whales
Tougaard, Jakob; Luke, Klaus; Siebert, Ursula et al

Poster (2017)

Detailed reference viewed: 20 (1 ULg)
Full Text
See detailConstraints on quasar broad line regions from microlensing
Hutsemekers, Damien ULg; Braibant, Lorraine ULg; Sluse, Dominique ULg et al

Conference (2017)

Gravitational microlensing is a powerful tool allowing one to unveil the structure of quasars on sub-parsec scale, and in particular of the broad emission line region. This is possible owing to the ... [more ▼]

Gravitational microlensing is a powerful tool allowing one to unveil the structure of quasars on sub-parsec scale, and in particular of the broad emission line region. This is possible owing to the analysis of the microlensing-induced broad line deformation (core/wings or red/blue) observed in some gravitationally lensed quasars. After a description of examples of strong profile deformations, different in low- and high-ionization lines, we present newly developed simulations of line profile changes for various models of the emission line region in presence of microlensing. We explain how these simulations, confronted to observations of microlensed quasars, strongly favors the Keplerian disk model for the low-ionization emission line region. We also discuss how microlensing helps to probe the structure of other unresolved components, such as the broad absorption line and the continuum scattering regions. [less ▲]

Detailed reference viewed: 23 (2 ULg)
Peer Reviewed
See detailStudies on sperm whales (Physeter macrocephalus) stranded on the coast of Schleswig-Holstein, Germany in 2016.
Piatkowski, Uwe; Wohlsein, Peter; Van Neer, Abbo et al

Poster (2017)

Detailed reference viewed: 26 (2 ULg)
Peer Reviewed
See detailIMPACT OF IMAGE BRIGHTNESS REDUCTION ON PERCEIVED QUALITY OF 3D EXPERIENCE FOR 3D CINEMA SPECTATORS
Loock, Severin; Grogna, David ULg; Jaspar, Mathieu ULg et al

in International Conference on 3D Imaging (IC3D) (2017)

3D movies are calibrated to meet a certain screen bright- ness standard. Therefore, what would be the consequences on the quality of the 3D experience for spectators watching a 3D movie when movie ... [more ▼]

3D movies are calibrated to meet a certain screen bright- ness standard. Therefore, what would be the consequences on the quality of the 3D experience for spectators watching a 3D movie when movie theaters do not respect this standard? First, we attempted to better understand which factors were important for a spectator by conducting an experiment where participants watched a 3D movie and filled out an exploratory questionnaire. Then, we aimed to investigate the link between image brightness loss and the quality of the 3D experience as perceived by the spectator. First results show no perceived difference in the quality of the 3D experience between a nor- mal brightness and a brightness decreased by 10% for four factors, i.e. (1) the appreciation of the movie, (2) the con- tent of the movie, (3) the 3D quality of the movie, and (4) the quality of the 3D experience in general. [less ▲]

Detailed reference viewed: 12 (1 ULg)
Full Text
See detailBenthic contributions to Adriatic and Mediterranean biogeochemical cycles
Capet, Arthur ULg; Lazzari, Paolo; Spagnoli, Federico et al

Conference (2017)

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailUne évaluation mutuelle pour soutenir les processus d’apprentissage et transformer les pratiques d’enseignement : ce qu’en disent de futurs enseignants du secondaire
Fagnant, Annick ULg; Goffin, Christelle ULg

in 29e colloque de l'Admée Europe - L'évaluation : levier pour le développement professionnel et les apprentissages (axe 4) (2017)

Dans une étude qui s’intéressait aux conceptions de futurs enseignants du secondaire (Goffin & Fagnant, 2016), nous avons notamment montré que ces derniers témoignent d’expériences très limitées en ... [more ▼]

Dans une étude qui s’intéressait aux conceptions de futurs enseignants du secondaire (Goffin & Fagnant, 2016), nous avons notamment montré que ces derniers témoignent d’expériences très limitées en matière d’évaluation formative : leur vécu en tant qu’élève fait davantage état de pratiques d’auto-notations (Rey & Feyfant, 2014) que de réelle autoévaluation. Sur la base de ce constat, nous leur avons fait vivre une expérience d’évaluation mutuelle (Bourgeois & Laveault, 2015) dans le cadre d’un cours de pédagogie générale. Cette communication présentera le dispositif mis en place, tout en y portant un regard critique documenté par plusieurs sources d’informations. En préparation de la séance-cible, les étudiants étaient invités à analyser une de leurs séquences à l’aide de la grille CompAS (Parmentier & Paquay, 2002). Ils devaient rédiger un texte présentant cette analyse et étaient prévenus que cette première ébauche serait évaluée par un autre étudiant en vue d’être retravaillée pour figurer dans leur rapport final. Après avoir pris connaissance et discuté de l’évaluation réalisée par un autre étudiant, ils ont pu affiner et poursuivre le travail initialement demandé, notamment en développant des pistes touchant aux différentes formes d’évaluation qu’ils pourraient pratiquer en classe avec leurs élèves dans le cadre de cette séquence de cours. Quelques exemples, issus des 231 travaux réflexifs recueillis en fin d’année, permettront d’illustrer leur compréhension de la perspective élargie de l’évaluation formative (Allal & Mottier Lopez, 2005). Une analyse des commentaires rédigés par les étudiants suite à l’expérience d’évaluation mutuelle vécue permettra également de pointer les avantages et les limites qu’ils perçoivent à ce dispositif et les retombées qu’ils envisagent pour leurs pratiques de classes. Outre quelques limites relevées, les résultats sont globalement positifs et montrent que cette expérience a ainsi pu, dans une certaine mesure, nourrir leurs processus d’apprentissage et leur développement professionnel. [less ▲]

Detailed reference viewed: 34 (4 ULg)
Full Text
Peer Reviewed
See detailThermo-economic optimization during preliminary design phase of organic Rankine cycle systems for waste heat recovery from exhaust and recirculated gases of heavy duty trucks
Guillaume, Ludovic ULg; Legros, Arnaud; Dickes, Rémi ULg et al

in IMechE (Ed.) Vehicle Thermal Management Systems conference (2017)

Waste heat recovery (WHR) Organic Rankine Cycle (ORC) system is a very promising technology for reducing fuel consumption and consequently the CO2 emissions of future heavy-duty trucks (HDT). Nonetheless ... [more ▼]

Waste heat recovery (WHR) Organic Rankine Cycle (ORC) system is a very promising technology for reducing fuel consumption and consequently the CO2 emissions of future heavy-duty trucks (HDT). Nonetheless, the adoption of this technology in the automotive domain requires specific R&D activities going from the system definition to the on-board integration. This study focuses on the preliminary design phase of ORC systems recovering the heat wasted from two of the sources available on a HDT: the exhaust and recirculated gases. From these heat sources and their combinations, 6 possible architectures are identified. On the other hand, 4 volumetric expansion machine technologies are considered (scroll, screw, piston and vane Expanders). At the end, 24 topologies are therefore modelled considering the main components (Pump, Heat exchangers, Expansion machines). A three-step optimization method is proposed to identify the most promising system. First, the most suitable conditions are identified for the design of the ORC systems using a simple model of volumetric expansion machine. In a second step, the design phase, using more detailed models for the expansion machines, a thermos-economic optimization is performed. Finally, in a third step, the output power of the latter system models is maximized in off-design conditions, optimizing the evaporating pressure and the overheating degree. [less ▲]

Detailed reference viewed: 45 (7 ULg)
Peer Reviewed
See detailUrodynamic and morphometric characteristics of the lower urogenital tract in growing male Beagle littermates
Porato, Mathilde ULg; Noël, Stéphanie ULg; Bolen, Géraldine ULg et al

in Congress of the European Veterinary Society for Small Animal Reproduction : Vienna, Austria June 29 - July 1, 2017 (2017)

Detailed reference viewed: 7 (1 ULg)
Full Text
See detail[18F]UCB-H RADIOTRACER AS A TOOL TO UNDERSTAND THE ROLE OF THE SV2A PROTEIN
Serrano Navacerrada, Maria Elisa ULg; Becker, Guillaume ULg; Bahri, Mohamed Ali ULg et al

Poster (2017)

Background: SV2A is the most studied isoform of the Synaptic Vesicle 2 proteins, which are involved in the synaptic vesicle trafficking, being important both in normal as in pathological process (1, 2 ... [more ▼]

Background: SV2A is the most studied isoform of the Synaptic Vesicle 2 proteins, which are involved in the synaptic vesicle trafficking, being important both in normal as in pathological process (1, 2). Until now, only one study in vivo has been reported, showing a reduction of SV2A levels in the epilepsy (3). [18F]UCB-H was developed like a current tool to study the role of SV2A with in vivo techniques (4, 5), and as a tool in clinical investigations. The objective of this research was to evaluate the radiotracer specificity to this isoform comparing with the others, through a competition assay in rats with ex-vivo autoradiography and mPET imaging. Methods: Forty male Sprague-Dawley were used in ex-vivo autoradiography experiments (N=20) and in microPET imaging (N=20). Animals were pre-treated 30 minutes before the injection of [18F]UCB-H with a dose IP either of vehicle, Keppra (SV2A ligand), UCB068 (SV2B ligand) or UCB054 (SV2C ligand). Ex-vivo autoradiography was carried out 5 minutes after radiotracer injection while mPET images were acquiring with a dynamic scanner of 1 hour. Standard Uptake Value (SUV) and Distribution Volume (VT) were calculated and the correlation between both parameters was determined. Results: In ex-vivo autoradiography, ANOVA of two-ways showed statistical significant differences in brain uptake of [18F]UCB-H among the groups pretreated with Keppra or the ligand for SV2B and the control group. Regarding mPET data, statistical significant differences were found between the group injected with keppra and the rest of groups. Pearson Correlation between SUV and VT was strong, with a value of 0.955. Conclusion: Even if a considerable affinity between the ligands UCB068 and UCB054, and the receptor for the isoform SV2A exists, it is only detected during the first 5 minutes (ex-vivo technique), being certainly due to a nonspecific binding. This binding is not strong enough to show a direct competition with the radiotracer during a mPET acquisition. These results allow us to conclude that [18F]UCB-H is a suitable radiotracer for the imaging of the isoform SV2A in vivo, allowing us the clinical study about the molecular base of a disease with a high population impact, like the epilepsy. 1) Van Vliet et al., 2009. Epilepsia 2) Crèvecœur et al., 2013. BMC Neurosci. 3) Finnema et al., 2016; Sci Transl Med. 4) Bretin et al., 2013.EJNMMI Res 5) Bretin et al., 2015.Mol Imaging Biol [less ▲]

Detailed reference viewed: 15 (2 ULg)
See detailFrançois Ier et les arts du Nord (1515-1547). Des liens à explorer et à appronfondir encore
Fagnart, Laure ULg; Lecocq, Isabelle

in Fagnart, Laure; Lecocq, Isabelle (Eds.) François Ier et les arts du Nord (1515-1547) (2017)

Detailed reference viewed: 28 (3 ULg)
Full Text
Peer Reviewed
See detailResults of the SarcoPhAge study after 2 years of follow-up.
Beaudart, Charlotte ULg; Locquet, Médéa ULg; Reginster, Jean-Yves ULg et al

in Journal of Frailty & Aging (2017), 6 Suppl 1

Detailed reference viewed: 16 (1 ULg)
Full Text
Peer Reviewed
See detailA Comparison of Micro-objective Non-parametric Statistical Matching Techniques for the Integration of Different Survey Data
Eftekhar, Hamed ULg; Cools, Mario ULg

in Proceedings of the 96th Annual Meeting of the Transportation Research Board (2017)

Lack of information is often reported as one of the main study limitations in transport research. Other data sources provide an important opportunity, as the information from these data sources might be ... [more ▼]

Lack of information is often reported as one of the main study limitations in transport research. Other data sources provide an important opportunity, as the information from these data sources might be fully exploited when they are integrated using an appropriate mathematical framework. This paper determines which data integration techniques can be adopted in the context of road safety, and which criteria should be used to assess the quality of the integrated dataset. The paper contributes to the literature by providing a comparison of different techniques that allow the tabulation of the joint micro-data. To compare the suitability of different Statistical Matching techniques, data from the 2012 Belgium Road Safety Institute (BRSI) Attitude Survey and data from the 2010 Belgian National Household Travel Survey (BELDAM) are integrated. In particular, the socio-economic factor "Income" is being matched to the BRSI Attitude Survey data. The paper discusses and compares different non-parametric micro-objective Statistical Matching techniques, in which the “Income” variable from the BELDAM survey was added to the BRSI Attitude Survey. Based on similarity/dissimilarity measures, the Rank hot-deck Statistical Matching yielded the best result, which is in line with the existing literature. Moreover, from the results, it can be concluded that statistical data matching is a practically applicable technique, which can help overcome the lack of additional information. Further research should focus on using the integrated datasets with an attempt of expanding the scope of variables, and explicitly testing for omitted variable bias. [less ▲]

Detailed reference viewed: 38 (7 ULg)
Full Text
See detailÉtude de la spécificité d’épreuves langagières chez des enfants présentant une dyspraxie verbale (DV) vs un trouble phonologique (TP)
Masson, Pauline ULg; Martinez Perez, Trecy ULg

Poster (2017)

Malgré une augmentation de la recherche sur la dyspraxie verbale, l’évaluation de ce trouble langagier reste problématique. La littérature propose une variété de critères pour le diagnostic de la ... [more ▼]

Malgré une augmentation de la recherche sur la dyspraxie verbale, l’évaluation de ce trouble langagier reste problématique. La littérature propose une variété de critères pour le diagnostic de la dyspraxie verbale, cependant la majorité des caractéristiques cliniques sont également partagées avec les troubles phonologiques (Davis & Velleman, 2000 ; Murray et al., 2015). L’objectif de cette recherche est de déterminer des épreuves qui permettent de différencier une dyspraxie verbale et un trouble phonologique. Nous avons exploré les marqueurs les plus couramment utilisés dans la littérature : l’imprécision des productions phonologiques et l’intelligibilité réduite (Aziz et al., 2010), l’inconstance des erreurs (Forrest, 2003 ; Tubul-Lavy, 2012), la prosodie inappropriée (Shriberg et al., 2003) et la lenteur d’articulation (Shriberg, 2013). Nous avons récolté des données auprès de deux groupes d’enfants francophones présentant une dyspraxie verbale (N=12) ou un trouble phonologique (N=12). Nos deux groupes sont appariés sur le score du QI non verbal, le niveau de compréhension orale et le niveau socio-économique. Les résultats de cette recherche mettent en évidence quatre mesures dont les valeurs de sensibilité/spécificité sont entre acceptables (>80%) et bonnes (>90%) : les pourcentages de réponses correctes et de consonnes correctes à une épreuve de dénomination d'images ; la stabilité des productions dans une épreuve de récit sur images (mots présentés à trois reprises) ; et la vitesse d’articulation pour la série diadocosinésique /pataka/. Pour ces quatre mesures, les résultats montrent que la dyspraxie verbale et le trouble phonologique se situent sur un continuum de sévérité (la dyspraxie verbale entrainant des manifestations plus sévères que le trouble phonologique). Ces résultats seront discutés lors de la session poster. [less ▲]

Detailed reference viewed: 436 (9 ULg)
Peer Reviewed
See detailImproved high throughput DNA-seq based mapping of HTLV-1 integration sites: a tool to define response to treatment, ATL prognosis and guide therapeutic strategies
Marçais, Ambroise; Artesi, Maria ULg; Durkin, Keith ULg et al

Conference (2017)

Background Adult T-cell leukemia/lymphoma (ATL) is an aggressive CD4+ T-cell malignancy caused by HTLV-1 infection and associated with extremely poor prognosis. In France, treatment strategies mainly ... [more ▼]

Background Adult T-cell leukemia/lymphoma (ATL) is an aggressive CD4+ T-cell malignancy caused by HTLV-1 infection and associated with extremely poor prognosis. In France, treatment strategies mainly include chemotherapy, antiviral therapy and allogeneic stem cell transplantation, based on clinical subtype and therapeutic responses. Response to treatment is evaluated based on consensus criteria defined in 2009 (Tsukasaki K, Hermine O et al, JCO 2009). Although immuno-phenotyping, TCRγ rearrangement and HTLV-1 proviral load (PVL) quantification are often assayed, complete clinical remission (CR) is currently defined by morphological and cytological criteria i.e. complete blood cell counts (CBC) and the presence of abnormal lymphocytes. Given the extremely poor prognosis and high rates of early relapse, a revision of the response criteria is required, calling for improved tools that integrate specific aspects of the pathophysiology of ATL to better estimate response to treatment. Methods We retrospectively analyzed longitudinal PBMC samples from 6 ATL patients diagnosed with a leukemic subtype (5 acute and 1 chronic-aggressive) which all achieved CR upon therapy, yet relapsed after a median time of 15,9 months (range 2,4-70,7). CR was assessed by morphological and cytological criteria. An improved high throughput sequencing (HTS) based method was utilized to map and quantify the abundance of HTLV-1 genomic integration sites (IS), overcoming some of the limitations of previously published protocols. The dynamic range was increased by assaying both the 5’LTR and 3’LTRs, allowing better determination of clone abundance and revealing 5’ deletions. An enrichment step limited PCR duplicates. The addition of off-the-shelf Illumina primers simplified library multiplexing and reduced the costs to the point where the protocol could be applied to a clinical setting. Results HTS- mapping of HTLV-1 IS at diagnosis revealed in all cases a unique IS that constituted 92-99% of proviral genomes, with PVLs of 33-510%. All patients were treated and achieved CR which was characterized by normalized CBC, <5% abnormal lymphocytes and the absence of measurable tumors for >4 weeks. For 3/6 patients, the clone frequency distribution of HTLV-1 infected cells at CR was composed of multiple low abundance clones, of which the unique presumed malignant IS contributed to less than 2% of proviral genomes. In contrast, clonality analysis of the remaining 3/6 patients revealed that the relative abundance of the malignant clone detected at diagnosis remained dominant at CR (36-83% of PVL), despite clinical response criteria typical of CR and a 3-20-fold decrease in PVLs. These patients relapsed after 2.4, 2.9 and 3.4 months respectively with a dominant malignant clone >95% while patients with a polyclonal architecture showed significantly longer CR (28, 59 and 71 months). Conclusions Our observations highlight the great heterogeneity within an identical CR group, underlining the need for revisiting response criteria for ATL. Our results call for the use of this improved HTS-based method to measure HTLV-1 clonality as a tool to better estimate response to treatment, predict relapse and guide therapeutic choices in the course of treatment. [less ▲]

Detailed reference viewed: 33 (6 ULg)
Peer Reviewed
See detailShape and size variations of the bony components of sperm whale cochleae
Schnitzler, Joseph ULg; Frederich, Bruno ULg; Früchtnicht, Sven et al

Conference (2017)

Detailed reference viewed: 18 (1 ULg)
Peer Reviewed
See detailStudy of virus-like particles of human papillomavirus in capillary electrophoresis
Bettonville, Virginie ULg; Nicol, Jérôme; Furst, Tania et al

Poster (2017)

Detailed reference viewed: 38 (8 ULg)
See detailThiamine: Biological forms and function
Bettendorff, Lucien ULg

Conference (2017)

Detailed reference viewed: 33 (0 ULg)
Full Text
Peer Reviewed
See detailEffects of a giant exercising board game intervention on ambulatory physical activity among nursing home residents: a preliminary study
Mouton, Alexandre ULg; Gillet, Nicolas; Mouton, Flore et al

in Osteoporosis International (2017), 28(S1), 318

Detailed reference viewed: 37 (0 ULg)
See detailNitrous oxide dynamic in sea ice
Kotovitch, Marie ULg; Fripiat, François ULg; Deman, Florian et al

Poster (2017)

Fluctuations in greenhouse gases (GHGs) concentration alter the energetic budget of the climate system. There is high confidence that natural systems related to snow, ice and frozen ground are affected ... [more ▼]

Fluctuations in greenhouse gases (GHGs) concentration alter the energetic budget of the climate system. There is high confidence that natural systems related to snow, ice and frozen ground are affected. Nitrous oxide (N2O) is one of the potent GHG naturally present in the atmosphere, but witch has seen his concentration growing since industrial era. N2O has a lifetime in the atmosphere of 114 years and a global warming potential 300 time higher than that of CO2. Yet, there are still large uncertainties and gaps in the understanding of the cycle of this compound through the ocean and particularly in sea ice. Sources and sinks of N2O are therefore still poorly quantified. The main processes (except the transport processes) involved in the N2O cycle within the aquatic environment are nitrification and denitrification. To date, only one study by Randall et al. 2012 present N2O measurements in sea ice. Randall et al. pointed out that sea ice formation and melt has the potential to generate sea-air or air-sea fluxes of N2O, respectively. Study on ammonium oxidation and anaerobic bacterial cultures shows that N2O production can potentially occur in sea ice. Denitrification can act as a sink or a source of N2O. In strictly anaerobic conditions, N2O is removed by denitrification. However, denitrification can also occur in presence of O2 at trace level concentrations (<0.2 mg L-1), and in these conditions there is a large N2O production. Recent observations of significant nitrification in Antarctic sea ice shed a new light on nitrogen cycle within sea ice. It has been suggested that nitrification supplies up to 70% of nitrate assimilated within Antarctic spring sea ice. Corollary, production of N2O, a by-product of nitrification, can potentially be significant. This was recently confirmed in Antarctic land fast ice in McMurdo Sound, where N2O release to the atmosphere was estimated to 4 µmol.m-2.yr-1. This assessment is probably an underestimate since it only accounts for dissolved N2O while a significant amount of N2O is likely to occur in the gaseous form like N2, O2 and Ar. This poster address the issue related to the production of N2O within sympagic microorganisms. What process is dominant and how much N2O is produced? The determination of the isotopic composition of N2O using cavity enhanced laser absorption spectroscopy technique (Off-axis ICOS) will allow us to determine the origin of these processes. It will be based on the relative isotope abundance values and site preference data in previous studies. [less ▲]

Detailed reference viewed: 19 (6 ULg)
Full Text
Peer Reviewed
See detailSpecification guidelines for surface preparation of concrete prior to repair
Courard, Luc ULg; Bissonnette, Benoît; Garbacz, Andrzej

in High Tech Concrete: Where Technology and Engineering Meet (2017)

The repair of concrete requests specific preparation operations needed for guaranteeing compatibility between substrate and new materials as well as the development of adhesion properties. These ... [more ▼]

The repair of concrete requests specific preparation operations needed for guaranteeing compatibility between substrate and new materials as well as the development of adhesion properties. These specification guidelines contain design and construction recommendations for surface preparation of concrete for repair and overlay. The paper summarizes current knowledge, best practices and results of the research concerning the surface preparation of concrete prior to application of repair/overlay materials. The specifications are applicable to repairing damaged or deteriorated concrete structures, correcting design or construction deficiencies, or upgrading a structure for new uses, or to meet more restrictive code requirements. This is based on 10 years research activities on this topic through scientific cooperation programs between Wallonia, Quebec and Poland and support of American Concrete Institute. [less ▲]

Detailed reference viewed: 17 (2 ULg)
Full Text
Peer Reviewed
See detailHealth outcomes of sarcopenia: a systematic review and metaanalysis.
Beaudart, Charlotte ULg; Zaaria, M.; Pasleau, Françoise ULg et al

in Osteoporosis International (2017), 28 Suppl 1

Detailed reference viewed: 32 (3 ULg)
Full Text
Peer Reviewed
See detailOn the Elaboration of Metal-Ceramic Composite Coatings by Laser Cladding
Mertens, Anne ULg; L'Hoest, Thibaut; Magnien, Julien et al

in Materials Science Forum (2017), 879

This paper reports on a preliminary investigation into the elaboration, by the additive process known as laser cladding, of composite coatings with a matrix of stainless steel 316L reinforced with varying ... [more ▼]

This paper reports on a preliminary investigation into the elaboration, by the additive process known as laser cladding, of composite coatings with a matrix of stainless steel 316L reinforced with varying contents of tungsten (WC) or silicon carbides (SiC) particles. Laser cladding is characterised by ultra-fast solidification and cooling rates, thus giving rise to ultra-fine out-of-equilibrium microstructures and potentially enhanced mechanical properties. Both types of composite coatings – i.e. with SiC or WC ‒ are compared in terms of their microstructures and hardness. Special attention is given to the dissolution of the carbides particles and to interfacial reactions taking place between the particles and the metallic matrix. [less ▲]

Detailed reference viewed: 96 (18 ULg)
Full Text
Peer Reviewed
See detailA surprising and dramatic neuroendocrine-immune phenotype of mice deficient in Growth Hormone-Releasing Hormone (GHRH)
Farhat, Khalil; Bodart, Gwennaelle; Martens, Henri ULg et al

in Neuroimmunomodulation (2017)

Detailed reference viewed: 37 (7 ULg)
Full Text
Peer Reviewed
See detailAssessing Inter- and Intramolecular Continuous-Flow Strategies towards Methylphenidate Hydrochloride
Gerardy, Romaric ULg; Winter, Marc; Vizza, Alessandra et al

in Reaction Chemistry and Engineering (2017), 2(2), 149-158

Detailed reference viewed: 22 (7 ULg)
Full Text
See detailIN VIVO STUDY OF THE SV2A PROTEIN IN AN EPILEPTIC RAT MODEL
Serrano Navacerrada, Maria Elisa ULg; Becker, Guillaume ULg; Bahri, Mohamed Ali ULg et al

Poster (2017)

Introduction Epilepsy is one of the commonest neurological disorders, affecting more than 60 million people worldwide [1]. New and effective antiepileptic drugs mainly target the SV2A protein [2] but its ... [more ▼]

Introduction Epilepsy is one of the commonest neurological disorders, affecting more than 60 million people worldwide [1]. New and effective antiepileptic drugs mainly target the SV2A protein [2] but its actual role is still largely unknown. [18F]UCB-H was developed as a tool to study in vivo the brain expression of this isoform [3, 4]. Due to the fact that only post-mortem studies were reported so far [5] the present pilot study was undertaken in order to evaluate for the first time in vivo in rats the SV2A expression in the validated Kaïnic Acid (KA) epilepsy model [6]. Methods Three male Sprague-Dawley were used, one injected with saline (Sham) and two with multiple KA systemic injections (5mg/kg x 3) [9]. SV2A brain levels were estimated at day 75, when spontaneous seizures started to appear. Animals were anesthetized (2.5 to 3 % isoflurane), and scanned for 1 hour with [18F]UCB-H (41 ± 5 MBq IV tail vein) in a Focus 120 microPET system and with MRI (9.4T Agilent, anatomical T2). Coregistration was done with PMOD 3.6 software. Data were expressed in SUV and areas under the curve were calculated for the different regions. Results [18F]UCB-H microPET images showed an important reduction (20-30%) for SV2A after KA injections mainly localized in amygdala, hippocampus, lateral parietal association cortex and cingulate cortex. The rest of the brain was globally unchanged. MRI revealed atrophy and inflammation in amygdala and hippocampus. Conclusions These preliminary results in KA treated rats presenting spontaneous seizures showed that [18F]UCB-H microPET was able to detect important reductions for the SV2A proteins in relevant regions for epilepsy [5]. Accordingly to this, we can infer that the KA model in rats deserves for further development and validation as a tool for the study of epilepsy. [18F]UCB-H appears as a valuable tool to follow in vivo SV2A proteins through longitudinal protocols and in turn to better understand its actual role in epilepsy. References/acknowledgements This work was funded by University of Liège, F.R.S.-FNRS, Walloon Region and UCB Pharma. Alain Plenevaux is research director from F.R.S.-FNRS. [1] Alexopoulos, Epileptology, 2004 [2] Hamann et al., Eur J Pharmacol, 2008 [3] Bretin et al., Molecular Imaging and Biology, 2015 [4] Warnock et al., J Nucl Med., 2014 [5] Wang et al., J Mol Neurosci., 2014 [6] Hellier et al., Epilepsy Res., 1998 [less ▲]

Detailed reference viewed: 13 (1 ULg)
See detailLes « Annonciades » à Namur : première comparaison architecturale des « Rouges » et des « Célestes » installées au sein d’une même cité
Piront, Julie ULg

in Actes du 9e Congrès de l'Association des Cercles francophones d'Histoire et d'Archéologie de Belgique (2017)

En 1502, les Annonciades sont fondées en France par Jeanne de Valois, épouse répudiée du roi de France, Louis XII. La règle franciscaine dicte le mode de vie de ces religieuses. Elles sont vêtues d’un ... [more ▼]

En 1502, les Annonciades sont fondées en France par Jeanne de Valois, épouse répudiée du roi de France, Louis XII. La règle franciscaine dicte le mode de vie de ces religieuses. Elles sont vêtues d’un scapulaire rouge enfilé sur une robe grise, avec une voile noir. Un couvent de ces Annonciades de France, dites « rouges », est fondé à Namur en 1623. Cent ans plus tard, l’ordre des Annonciades célestes apparaît en 1602 en Italie, créé par Vittoria Fornari, dame de la petite noblesse génoise. Puisant ses préceptes dans la règle de saint Augustin, il est alors connu sous le nom de « l’ordine della Santissima Annunziata » (en français, « l’ordre de la Très Sainte Annonciade »). Ces religieuses sont identifiables par la couleur de leur costume : un scapulaire et un manteau « bleu céleste », portés sur une robe blanche et un voile noir. L’ordre gagne rapidement la France puis la Belgique. Un couvent est établi à Namur en 1631. Ces deux communautés revendiquaient donc le nom d’« Annonciades » et se côtoyèrent parfois dans une même ville. Ce fut le cas à Namur où elles s’établirent toutes les deux en moins d’une décennie. Ces circonstances offrent des dénominateurs communs pour permettre une comparaison architecturale inédite de ces deux établissements. Si le couvent des Annonciades célestes demeure partiellement conservé, celui des Annonciades rouges a disparu. Néanmoins, les sources archivistiques et iconographiques permettront de documenter l’analyse du plan de ces deux édifices ainsi que des matériaux de construction. Si le lieu d’implantation de ces bâtiments influencera probablement les techniques de construction, les différences entre les deux règles surgiront peut-être dans le plan de l’édifice. [less ▲]

Detailed reference viewed: 27 (2 ULg)
Full Text
See detailBehavioural phenotyping of SV2A lox/lox mice: Motor and anxiety-like features
Serrano Navacerrada, Maria Elisa ULg; Bartholomé, Odile ULg; Van Den Ackerveken, Priscilla ULg et al

Poster (2017)

Background: Epilepsy is one of the most common neurological disorders (Alexopoulos, 2004). Current anti-epileptic drugs, such as Levetiracetam (Keppra®) or Brivaracetam, mainly target the trans-membrane ... [more ▼]

Background: Epilepsy is one of the most common neurological disorders (Alexopoulos, 2004). Current anti-epileptic drugs, such as Levetiracetam (Keppra®) or Brivaracetam, mainly target the trans-membrane Synaptic Vesicle Protein 2A (Hamann et al., 2008). Studies on homozygous SV2A KO mice phenotype, prove the mice to suffer severe seizures and die within 3 weeks (Crowder et al., 1999), establishing a link between this protein and the epilepsy. In 2009, the availability of heterozygous SV2A (+/-) mice as research tool enabled shedding light on the role of protein SV2A, revealing no motor differences but anxiety-like features in these mice compared with the WT (Lamberty et al., 2009), and a pro-epileptic phenotype (Crowder et al., 1999; Kaminski et al., 2008). Recently, a floxed SV2A mouse model has been produced with the Cre/loxP recombination system, this model allows invalidating the protein in CA3 hippocampal region, not followed by epileptic seizures (Menten-Dedoyart et al., 2016). Objectives: Perform a first behavioural phenotyping of SV2A lox/lox mice. Methodology: Two experiments were conducted in parallel to evaluate the effect of 3 different genotypes in the phenotype: WT (Grik4-/-, SV2A lox/lox), HZ (Grik4 +/-, SV2A lox/+) and cKO (Grik4 +/-, SV2A lox/lox) in male (n = 42) and female (n = 33) separately . Mice were housed individually along the experiment, with standard food and water ad libitum. After an acclimatization period of 2 weeks, anxiety-like features as well as exploration abilities were evaluated in an elevated plus-maze (EPM) single session of 5 minutes). 3 days later, spontaneous locomotor activity and habituation to the environment were measured during 1 hour, 3 consecutive days, in the activity chambers (ACT). Results: One-way ANOVA in EPM data presented no significant differences between groups, either in males or in females. A significant difference was found, between time spent in close arms vs open arms (p<0.01; η2p = 0.738 males; η2p = 0.805 females). Mixed between-within subjects ANOVA in ACT reflected no significant differences between groups in both sexes, regarding spontaneous locomotor activity and acclimatization to the activity chamber (p>0.05). Statistical significant differences were found between the 3 days (p<0.01; η2p = 0.716 males; η2p = 0.663 females). Conclusion: Results indicate that a decrease in the hippocampal expresion of SV2A protein does not lead to major behavioral changes. Regarding locomotor activity, the results found in heterozygous SV2A (+/-) mice are in line with (Lamberty et al., 2009), however, our mice did not present anxiety-like features, being necessary a global decrease in brain SV2A levels and not only a partial loss in a restricted region of the brain. Further analyses increasing the number of mice per group, will allow us to intensify our power value from 50-60% (females-males) up to 80%, with large effect size and a signification of p<0.05. An additional test to evaluate the spatial memory may help us better understand the effect a specific reduction in SV2A hippocampal expression has on the phenotype of mice. [less ▲]

Detailed reference viewed: 30 (1 ULg)
Full Text
Peer Reviewed
See detailLa tradition textuelle de la Continuation du ‘Roman de Guiron’
Veneziale, Marco ULg

in Duval, Frédéric; Leonardi, Lino; Trachsler, Richard (Eds.) Congrès international de linguistique et de philologie romanes (Nancy, 15-20 juillet 2013). Section 13 : Philologie textuelle et éditoriale (2017)

Detailed reference viewed: 25 (0 ULg)
Full Text
Peer Reviewed
See detailPreliminary assessment of the possibilities of the Particle Finite Element Method in the numerical simulation of bird impact on aeronautical structures
Cerquaglia, Marco Lucio ULg; Deliège, Geoffrey ULg; Boman, Romain ULg et al

in Procedia Engineering (2017), 173

As well known, in the analysis of bird impact events the bird is often reduced, even experimentally, to a surrogate projectile modeled as a weakly compressible fluid (typically a mixture of water and air ... [more ▼]

As well known, in the analysis of bird impact events the bird is often reduced, even experimentally, to a surrogate projectile modeled as a weakly compressible fluid (typically a mixture of water and air). From a numerical standpoint, the presence of a free surface and the strong interaction with the aircraft structures represent a limit for traditional computational fluid dynamics methods based on an Eulerian grid. On the other hand, classical Lagrangian methods cannot cope with the extremely large deformations experienced by the projectile during the impact. The Particle Finite Element Method (PFEM) is a Lagrangian particle method that can account for very large deformations, preserving the robustness and generality of the finite element method, and thus owning a key advantage over other approaches, e.g. Smoothed Particle Hydrodynamics (SPH), usually cursed with consistency and stability issues. To assess the possibilities of the method in the context of bird impact, theoretical analyses are initially performed based on the impact of a water jet on a rigid surface. Then, the influence of the geometry of a more realistic projectile is analyzed and the capability of the method to take into account separation and fragmentation is highlighted. [less ▲]

Detailed reference viewed: 49 (19 ULg)
Full Text
Peer Reviewed
See detailA computational model of mid-term outage scheduling for long-term system studies
Marin, Manuel ULg; Karangelos, Efthymios ULg; Wehenkel, Louis ULg

in PowerTech Manchester 2017 Proceedings (2017)

This paper presents a computational model of the mid-term outage scheduling process of electric power transmis- sion assets, to be used in long-term studies such as mainte- nance policy assessments and ... [more ▼]

This paper presents a computational model of the mid-term outage scheduling process of electric power transmis- sion assets, to be used in long-term studies such as mainte- nance policy assessments and system development studies, while accounting for the impact of outage schedules on short-term system operation. We propose a greedy algorithm that schedules the outages one by one according to their impact on system operation estimated via Monte-Carlo simulations. The model is implemented in JULIA and applied to the IEEE RTS-96. [less ▲]

Detailed reference viewed: 41 (6 ULg)
Full Text
See detailLA MESURE DE RELIQUAT AZOTÉ DANS LE SOL EN DÉBUT DE PÉRIODE DE LIXIVIATION (APL) : méthodologie et bilan après 12 années de contrôle des exploitations agricoles en Belgique (région wallonne)
Vandenberghe, Christophe ULg; Colinet, Gilles ULg; Khalidi, Mostafa et al

in Pin, Dominique; Thibault, Olivier (Eds.) DES TERRITOIRES À L’EUROPE : Construire ensemble les transitions environnementales (2017)

In 1991, the European Union enacted a “Nitrates” directive that each member state has had to translate into an action plan in its territory. One of the tools the Walloon region uses to control the ... [more ▼]

In 1991, the European Union enacted a “Nitrates” directive that each member state has had to translate into an action plan in its territory. One of the tools the Walloon region uses to control the implementation of this action programme is the measure of residual nitrogen in the soil at the beginning of the nitrate leaching period (Nitrogen Leaching Potential). From 2004 to 2007, this tool was used in a hundred-odd farms that had voluntarily requested an exemption from the maximum amount of spreadable farmyard manure. Since 2008, it can be used by the Walloon Administration in any farm located in a vulnerable area. [less ▲]

Detailed reference viewed: 18 (2 ULg)
Full Text
Peer Reviewed
See detailEncounters of the third kind: antonyms and tertium
Steffens, Marie ULg

in Studies van de BKL - Travaux du CBL - Papers of the LSB (2017), 11

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailAgent-based analysis of dynamic access ranges to the distribution network
Mathieu, Sébastien ULg; Ernst, Damien ULg; Cornélusse, Bertrand ULg

in Proceedings of the 6th European Innovative Smart Grid Technologies (ISGT) (2017)

There is a need to clearly state an interaction model that formalizes interactions between actors of the distribution system exchanging flexibility. In previous works we quantitatively evaluated the ... [more ▼]

There is a need to clearly state an interaction model that formalizes interactions between actors of the distribution system exchanging flexibility. In previous works we quantitatively evaluated the performance of five interaction models devised with industrial partners using the agent-based testbed DSIMA. Simulation results showed that these interaction models relying on active network management suffer from a lack of coordination between the distribution and the transmission system operator, activating flexibility simultaneously in opposite directions. This paper introduces a new interaction model fixing this issue based on dynamic access bounds to the network changing throughout the day and preventing the activation of flexibility leading to congestions. This new interaction model is implemented in DSIMA and compared to a model restricting the grid users to a very restrictive but safe access range. Results show that this new model allows to safely increase by 55% the amount of distributed generation in the network. [less ▲]

Detailed reference viewed: 401 (16 ULg)
Full Text
Peer Reviewed
See detailCodifying ‘Sacred Laws’ in Ancient Greece
Carbon, Jan-Mathieu ULg; Pirenne-Delforge, Vinciane ULg

in Jaillard, Dominique; Nihan, Christophe (Eds.) Writing Laws in Antiquity / L'écriture du droit dans l'Antiquité (2017)

Detailed reference viewed: 285 (10 ULg)
Peer Reviewed
See detailMeasured soil erosion and catchment sediment yield data from Africa: an overview
Vanmaercke, Matthias ULg; Poesen, Jean; Broeckx, Jente

Conference (2017)

Detailed reference viewed: 15 (6 ULg)
Full Text
See detailMaking Sense Out of Pulsating Pre-ELM and ELM White Dwarfs
Fontaine, Gilles; Istrate, Alina; Gianninas, Alexandros et al

in Astronomical Society of the Pacific Conference Series (2017), 509

We present a unified view of pulsations in both pre-ELM and ELM white dwarfs within the framework of state-of-the-art binary evolution calculations that take into account the combined effects of diffusion ... [more ▼]

We present a unified view of pulsations in both pre-ELM and ELM white dwarfs within the framework of state-of-the-art binary evolution calculations that take into account the combined effects of diffusion and rotational mixing. We find that rotational mixing is able to maintain against settling a sufficient amount of helium in the envelope in order to fuel pulsations through He II-He III ionization on the pre-ELM branch of the evolutionary track in the spectroscopic HR diagram. By the time such a low-mass white dwarf enters the ZZ Ceti instability strip on the cooling branch, settling has taken over rotational mixing and produced a pure H envelope. Such a star then pulsates again, but, this time, as a DA white dwarf of the ZZ Ceti type. [less ▲]

Detailed reference viewed: 9 (1 ULg)
Full Text
Peer Reviewed
See detailMachine Learning of Real-time Power Systems Reliability Management Response
Duchesne, Laurine ULg; Karangelos, Efthymios ULg; Wehenkel, Louis ULg

in PowerTech Manchester 2017 Proceedings (2017)

In this paper we study how supervised machine learning could be applied to build simplified models of real-time (RT) reliability management response to the realization of uncertainties. The final ... [more ▼]

In this paper we study how supervised machine learning could be applied to build simplified models of real-time (RT) reliability management response to the realization of uncertainties. The final objective is to import these models into look-ahead operation planning under uncertainties. Our response models predict in particular the real-time reliability management costs and the resulting reliability level of the system. We tested our methodology on the IEEE-RTS96 benchmark. Among the supervised learning algorithms tested, extremely randomized trees, kernel ridge regression and neural networks appear to be the best methods for this application. Furthermore, by using feature “importances” computed by tree-based ensemble methods, we were able to extract the most relevant variables to predict the response of real-time reliability management, and thus obtain a better understanding of the system properties. [less ▲]

Detailed reference viewed: 152 (22 ULg)
Full Text
Peer Reviewed
See detail(Re)productive Traditions in Ancient Egypt. Some considerations with a particular focus on literature and language(s)
Winand, Jean ULg

in Gillen, Todd (Ed.) (Re)productive Traditions in Ancient Egypt. (2017)

Detailed reference viewed: 80 (1 ULg)
Full Text
Peer Reviewed
See detailOn the Analysis of Internet Paths with DisNETPerf, a Distributed Paths Performance Analyzer
Wassermann, Sarah ULg; Casas, Pedro; Donnet, Benoît ULg et al

in Proc. 10th IEEE Workshop on Network Measurements (WNM) (2017)

Traceroute is the most widely used Internet path analysis tool today to study the topology of the Internet and to diagnose routing failures as well as poor performance events. A major limitation of ... [more ▼]

Traceroute is the most widely used Internet path analysis tool today to study the topology of the Internet and to diagnose routing failures as well as poor performance events. A major limitation of traceroute when the destination is not controllable by the user is its inability to measure reverse paths, i.e., the path from any given destination back to the source. This is a major drawback for ISPs, who need to understand the performance of the Internet paths connecting popular services (e.g., YouTube and Facebook) to their customers. Even if public servers and distributed measurement platforms can provide partial reverse path visibility through ad-hoc measurements, there is still a need for a structured approach capable of analyzing the performance of Internet paths connecting any pair of nodes (servers, routers, hosts, etc.). While the problem of reverse traceroute has been addressed in the past, proposed techniques rely on IP address spoofing – which might lead to security concerns, and assume the availability of certain route-tracking options –, which might not be available. In this paper, we introduce and evaluate DisNETPerf, a new tool which provides exactly the same type of information as traceroute, but for paths connecting arbitrarily selected nodes. DisNETPerf works by firstly locating probes (i.e., measurement points) that are the closest to a given target node, using them to perform traceroute measurements from the target point-of-view to a given destination for path performance monitoring and troubleshooting purposes. We propose two techniques for probe location, and demonstrate that the reverse path (from server to users) can be measured with very high accuracy in certain scenarios. We also analyze relevant characteristics of Internet paths and distributed measurement platforms, which reinforce the applicability and relevance of DisNETPerf in current Internet. [less ▲]

Detailed reference viewed: 108 (25 ULg)
Full Text
Peer Reviewed
See detailFlowConvertor: Enabling Portability of SDN Applications
Pan, Heng; Xie, Gaogang; Li, Zhenyu et al

in IEEE INFOCOM 2017 (2017)

Detailed reference viewed: 28 (1 ULg)
Full Text
Peer Reviewed
See detailLes frontières du droit à l'épreuve des films de mafias
Thirion, Nicolas ULg; Pasteger, David ULg

in Flores-Lonjou, Magalie (Ed.) Frontière(s) au cinéma - Actes des septièmes rencontres "Droit et cinéma" (2017)

demander dans quelle mesure l’injonction du brigand qui exige « la bourse ou la vie ! » peut être comparée à la norme de comportement édictée par un Etat sous la forme d’une loi, c’est poser la ... [more ▼]

demander dans quelle mesure l’injonction du brigand qui exige « la bourse ou la vie ! » peut être comparée à la norme de comportement édictée par un Etat sous la forme d’une loi, c’est poser la sempiternelle question de la frontière qui sépare le droit du non-droit, tout au moins dans une perspective juspositiviste, en tant que cette école de théorie du droit refuse de définir le phénomène juridique en se référant à une valeur ou un ensemble de valeurs. La frontière du droit et du non-droit est en effet particulièrement difficile à tracer, nonobstant plusieurs siècles de discussions philosophiques à ce sujet. Lorsque, fatigué de parcourir les chemins, le brigand décide de s’installer en ville pour s’y adonner au racket des commerçants du quartier et qu’il s’adjoint ensuite le concours d’autres bandits, c’est un gang de malfaiteurs qui voit le jour. Si, ultérieurement, ce gang se concerte avec d’autres bandes de truands pour s’épauler mutuellement dans les exactions auxquelles ils se livrent sur leurs territoires respectifs, il prend alors la forme d’une organisation criminelle ou, au sens large du terme, d’une « mafia ». Le cinéma de Francis Ford Coppola, Martin Scorsese, Brian De Palma, Sergio Leone ou bien encore Matteo Garrone, entre autres, dépeint, souvent avec réalisme, la genèse et le fonctionnement de telles organisations criminelles. La communication a proposé, au moyen d’illustrations tirées des films de ces grands cinéastes, une analyse de microscopie juridique du crime organisé. Une description serrée de la particule élémentaire du phénomène juridique, identifiée par Lucien François dans son ouvrage de théorie du droit Le cap des Tempêtes sous l’appellation de « jurème », met en lumière une indéniable proximité entre les techniques de pouvoir utilisées respectivement par le brigand isolé, la bande organisée et l’Etat souverain. En remontant ensuite vers la structure plus complexe d’un système étatique, on se demandera si, en fin de compte, dans la vision juspositiviste poussée au bout de sa logique par Lucien François, l’Etat ne pourrait être réduit, d’un point de vue ontologique, à un pouvoir de fait comparable, par les techniques de contrainte qu’il exerce sur ses sujets, à une organisation criminelle – abstraction faite des valeurs promues ou poursuivies par tel ou tel appareil étatique. [less ▲]

Detailed reference viewed: 129 (36 ULg)
Full Text
See detailThe theoretical instability strip of V777 Her white dwarfs
Van Grootel, Valérie ULg; Fontaine, Gilles; Brassard, Pierre et al

in Astronomical Society of the Pacific Conference Series (2017), 509

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailA best fit heuristic for the three-dimensional Bin Packing Problem with practical constraints from an air transportation application
Paquay, Célia ULg; Limbourg, Sabine ULg; Schyns, Michael ULg

in Proceedings of the BIVEC-GIBET Transport Research Days 2017 (2017)

This work considers the three-dimensional Multiple Bin Size Bin Packing Problem which consists in packing a set of cuboid boxes into containers of various shapes, while minimising unused space. The aim of ... [more ▼]

This work considers the three-dimensional Multiple Bin Size Bin Packing Problem which consists in packing a set of cuboid boxes into containers of various shapes, while minimising unused space. The aim of the present work is to find good initial solutions in short computational times. In this purpose, a fast best fit heuristic able to manage the different constraints to be met in transportation is developed. The heuristic is split into two distinct phases. The first phase deals with the packing of boxes into identical bins using an extension of the Extreme Points rule. During this phase, the fragility, stability and orientation of the boxes are taken into account, as well as the special shape of the bins and their weight capacity. The second phase considers the multiple types of available bins. If necessary, the best loading pattern identified is enhanced with respect to weight distribution in post processing. After parametrisation, computational experiments are performed on data sets specially designed for this application. The heuristic requires very short computational times to achieve promising results. [less ▲]

Detailed reference viewed: 41 (0 ULg)