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See detailInfections de la shère génitale
MELIN, Pierrette ULg; DESCY, Julie ULg; MEEX, Cécile ULg

in MELIN, Pierrette; POLET, Marianne (Eds.) Les infections de la sphère génitale. Bruxelles, Belgique (2016, September 29)

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See detailStructure of the classe D β-lactamase OXA-29, an original dimer
Kerff, Frédéric ULg

Conference (2016, September 29)

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See detailTransition to parenthood of lesbian parents: key processes and clinical implications
Scali, Thérèse ULg; D'Amore, Salvatore ULg; Haxhe, Stéphanie ULg et al

Conference (2016, September 29)

The transition to parenthood is a key process for understanding the development of family relationships in a systemic perspective. This process has been studied mostly in heterosexual families but very ... [more ▼]

The transition to parenthood is a key process for understanding the development of family relationships in a systemic perspective. This process has been studied mostly in heterosexual families but very few studies focus on families with same-sex families. This exploratory study analyzes the key passages of the transition from 17 lesbian headed families through a quantitative analysis of socio-demographic data, information about the coming-out, pair formation, project of the child, the child's arrival, as well as social and cultural pressures towards family and stressors. The main results show that the decision making to become parents is generally harmonious (70%) between the members of the couple, and only a few had substantial conflicts (17,1%). Moreover, the motivation to become parents seems to be stronger for the mother who carried the child (57, 1%)than for the social mother. The majority of the lesbian mothers reported no medical homophobia (64,3%) Regarding the caregiving tasks, they seem to be equally shared between social and biological mothers. In regards to the child, almost 70% are aware of their parents’ sexual orientation (as only 5.7% are not fully aware). Finally, no changes in the quality of relationship with the family of origin have been found after the birth of the baby. Clinical implications of these results will be discussed. [less ▲]

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See detailProphéties, lyrisme et chevalerie. Portrait de Jacques Le Gros, bourgeois de Paris († 1551)
Lambert, Adélaïde ULg

Conference (2016, September 29)

Notre communication consistait à analyser les documents qui encadrent la fresque épique Gerard du Frattre dans le manuscrit unique Paris, BnF, fr. 12791, copié intégralement de la main de Jacques Le Gros ... [more ▼]

Notre communication consistait à analyser les documents qui encadrent la fresque épique Gerard du Frattre dans le manuscrit unique Paris, BnF, fr. 12791, copié intégralement de la main de Jacques Le Gros, un marchand de soie parisien. Outre la table des matières de Gerard du Frattre, ce corpus est notamment composé d’un inventaire de la bibliothèque de Jacques Le Gros, de prophéties portant sur des événements politiques contemporains (entre autres, sur les guerres opposant François Ier à Charles Quint), de pièces de vers amoureuses, satiriques ou pieuses, d’un placard affiché sur les portes de Notre-Dame, etc. Copiés entre 1525 et 1545 puis rassemblés dans un même codex, ces documents constituent un témoignage exceptionnel sur les intérêts d’un bourgeois de Paris et, plus largement, sur ceux du public des réécritures médiévales, durant la première moitié du XVIe siècle. En guise de prolongement, les résultats de notre enquête pourront alimenter la question de l’influence qu’a pu exercer le contexte politique et social du début du siècle sur la refonte des légendes médiévales : les pièces qui accompagnent Gerard du Frattre peuvent-elles être considérées comme des éléments paratextuels susceptibles d’orienter l’interprétation de la fiction placée au centre du manuscrit ? [less ▲]

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See detailUsing a dynamic vegetation model for future projections of crop yields: simulations from the plot scale to the Belgian and European scales
Jacquemin, Ingrid ULg; Dury, Marie ULg; Henrot, Alexandra-Jane ULg et al

Conference (2016, September 29)

Dynamic vegetation models (DVM), such as CARAIB (“CARbon Assimilation In the Biosphere”) were initially designed to describe the dynamics of natural ecosystems as a function of climate and soil with the ... [more ▼]

Dynamic vegetation models (DVM), such as CARAIB (“CARbon Assimilation In the Biosphere”) were initially designed to describe the dynamics of natural ecosystems as a function of climate and soil with the aim of studying the role of vegetation in the carbon cycle. But their characteristics allow numerous other applications and improvements, such as the development of a crop module. This module can be validated at the plot scale, with the use of eddy-covariance data from agricultural sites in the FLUXNET network. The carbon fluxes (e.g., net ecosystem exchange (NEE), gross primary productivity (GPP)) and the evapotranspiration (ET) simulated with the CARAIB model are compared with the fluxes measured at several sites, in order to cover a maximum number of crop types (winter wheat/barley, sugar beets, potatoes, rapeseed,…) and to evaluate the model for different European regions (Belgium, France, Germany,…). The aim of this validation is to assess the model ability to reproduce the seasonal and inter-annual variability of carbon fluxes. In order to assess the spatial variability of the model, CARAIB will be applied over Belgium and forced with the outputs the regional climate model ALARO (4 km resolution), for the recent past and the decennial projections. To reach the larger scale, we also aim to assess crops yields over Europe and to quantify the uncertainties in the climatic projections. CARAIB will be driven with the outputs of different regional climatic models (RCMs), nested in CMIP5 GCM projections for the EURO-CORDEX project: ALADIN53 (Météo-France/CNRM), RACMO22E (KNMI), RCA4 (SMHI) and REMO2009 (MPI-CSC) RCMs. These climatic projections are at a high spatial resolution (0.11-degree, ≈12 km). The model will be set up for the most common crops in Europe and for simulations tests with marginal and/or new crops. Finally, this simulation ensemble will be used to highlight potential changes in the most productive areas of Europe. [less ▲]

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See detailMathematical modelling of ectopic bone formation in bone morphogenetic (BMP) carrier device
Manhas, Varun ULg; Carlier, Aurelie; Geris, Liesbet ULg

Conference (2016, September 28)

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See detailPratiques foncières dans les cuvettes oasiennes du Niger oriental
Malam Boukar, Awa Krou; Yamba, Boubacar; Ouassa, Tiekoura et al

Conference (2016, September 28)

La situation foncière en Afrique de l’Ouest francophone rurale se caractérise par la coexistence de différents systèmes de normes : aux règles foncières sociales, issues d’hybridations successives, se ... [more ▼]

La situation foncière en Afrique de l’Ouest francophone rurale se caractérise par la coexistence de différents systèmes de normes : aux règles foncières sociales, issues d’hybridations successives, se superpose un système juridique et réglementaire étatique (LAVIGNE Ph. 2000). L’Etat du Niger s’est engagé depuis les années 80 dans un processus visant à mettre en place des règles de gestion durable du foncier à travers le Code rural (Code Rural du Niger. 2013). De ce fait, la mise en perspective des spécificités des cuvettes oasiennes du Niger oriental ainsi que le cadre législatif devant permettre de gérer théoriquement le foncier est d’un intérêt croissant étant donné le nombre de problèmes récurrents et conjoncturels dans cette zone (ensablement, pression démographique, conflit foncier, enclavement). À la suite de ces constats, la mise en place de notre protocole de recherche tente d’établir un état des lieux du mode de fonctionnement et d’accès aux cuvettes oasiennes. La question de recherche s’énonce comme suit : « Comment s’effectue la pratique foncière dans les cuvettes oasiennes du département de Gouré ? ». La principale hypothèse du travail repose sur le fait que l’ensemble des cuvettes oasiennes du département de Gouré ont une gestion foncière relativement dépendante des chefs coutumiers et que ces derniers ne sont pas impliqués dans le processus du Code Rural Nigérien. [less ▲]

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See detailPerformance et circuit de commercialisation des principaux produits agricoles des cuvettes oasiennes du département de Gouré
Malam Boukar, Awa Krou; Yahaya, Abdou; Yamba, Boubacar et al

Conference (2016, September 28)

Les cuvettes oasiennes du département de Gouré sont sources de production alimentaire et de revenus pour les populations locales. Elles jouent un rôle important dans la lutte contre l’insécurité ... [more ▼]

Les cuvettes oasiennes du département de Gouré sont sources de production alimentaire et de revenus pour les populations locales. Elles jouent un rôle important dans la lutte contre l’insécurité alimentaire et la pauvreté. L’objectif de cet article est de démontrer l’efficacité économique des principaux produits agricoles de cuvettes ainsi que les plateformes de commercialisation. Pour ce faire, trois démarches méthodologiques complémentaires ont été adoptées. La première permet d’identifier les produits agricoles les plus rentables selon le point de vu des producteurs, la seconde permet déterminer les principaux produits agricoles de cuvettes à travers le « test de Kendall » et la troisième permet de calculer la rentabilité économique des produits à travers des indicateurs de performance. Pour cela, neuf cuvettes ont été choisies suivant le niveau de nappe phréatique et le type de valorisation. Les enquêtes réalisées et les constats effectués montrent que toutes les spéculations sont rentables, puisque leur RPN dépasse les 50%. Les producteurs indiquent que le manioc est la spéculation la plus importante du fait de sa mise en culture, de sa consommation et de sa conservation facile. Les deux autres tests montrent les cultures à cycle court comme le chou (75%) et l’oignon (69%) sont plus attrayants. Il est aussi ressorti que les produits agricoles de cuvettes sont plus destinés à la vente (73%) qu’à l’autoconsommation (27%) et les marchés locaux représentent les principales plateformes commerciales. [less ▲]

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See detailEvolution récente des extrêmes pluviométriques au Niger (1950-2014)
Ozer, Pierre ULg; Laminou, Manzo Ousmane; Tidjani, Adamou Didier et al

Conference (2016, September 28)

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See detailSystème d’exploitation et potentialités économiques des cuvettes oasiennes du sud-est du Niger
Malam Boukar, Awa Krou; Yamba, Boubacar; Lebailly, Philippe ULg

Poster (2016, September 28)

Les cuvettes oasiennes du sud-est nigérien sont sources de production alimentaire (JAHIEL. 1998). C’est pourquoi, les populations locales sont dépendantes des cuvettes pour leurs productions alimentaires ... [more ▼]

Les cuvettes oasiennes du sud-est nigérien sont sources de production alimentaire (JAHIEL. 1998). C’est pourquoi, les populations locales sont dépendantes des cuvettes pour leurs productions alimentaires et leurs revenus (TYCHON B. et al. 2009). Cette étude vise à démontrer l’importance socio-économique des cuvettes oasiennes du sud-est nigérien. [less ▲]

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See detailINNOVATIVE INJECTABLE LIPOSOME AND DRUG-IN-CYCLODEXTRIN-IN LIPOSOME SYSTEMS ENCAPSULATING ESTETROL FOR THE TREATMENT OF ISCHEMIA DISEASES IN PREMATURE BABIES
Palazzo, Claudio ULg; Laloy, Julie; Delvigne, Anne-Sophie et al

Conference (2016, September 28)

Purpose: In 2010, almost 15 million of babies in the world are prematurely borned, 11.1 % of the total amount of alive children. Despite the better neonatology techniques, the number of preterm babies ... [more ▼]

Purpose: In 2010, almost 15 million of babies in the world are prematurely borned, 11.1 % of the total amount of alive children. Despite the better neonatology techniques, the number of preterm babies with motor, vision, hearing or mental deficiencies is still constant along the last twenty years. Moreover, no efficacy treatment is available to the present day. The estetrol (E4) has an important role in the brain development and protection. The aim of this study is to develop new injectable liposome and drug-in-cyclodextrin-in-liposome (DCL) formulations, encapsulating E4 in order to enhance its crossing through the blood-brain barrier (BBB). Methods: Hydroxypropyl-β-cyclodextrins (degrees of substitution 0.87 and 0.63) (HPβCD 0.87 and HPβCD 0.63) were used to increase E4 aqueous solubility. Liposome and DCL (E4-HPβCD 0.63 complex) formulations were prepared by thin-film hydration technique. The formulations were physicochemical characterized and stability in foetal bovine serum (FBS) was evaluated. LDH and MTS tests on endothelial, neuronal and BBB model cells were performed in vitro on the liposome formulation. Hemocompatibility of the formulations was evaluated on red blood cells, platelet aggregation and coagulation. BBB passage tests were performed using human BBB cell line (hCMEC/D3). Results: E4-HPβCD complexes proportionally increased the solubility of the hormone. Due to the lower solubility obtained with HPβCD ds 0.87, only HPβCD ds 0.63 was retained for future tests. Liposomes and DCL encapsulating E4 were prepared. All the formulations had average particle size below 150 nm, polydispersity index below 0.10 and ζ potential around + 30 mV. The encapsulation efficacy for liposomes was between 3% and 10% while those of DCL are between 15% and 35%. Moreover, the formulations are capable to release 80 % (liposome) and 90 % (DCL) of encapsulated E4 after 3 h at 37°C. The formulations, incubated in FBS at 37°C under gentle stirring, keep the same size and do not form protein corona up to 6 h. The effect of liposome and DCL formulations on cell viability and integrity was evaluated. The results showed no toxic effects on all the tested cell lines. Hemocompatibility tests showed no hemolysis, platelet aggregation or effects on coagulation, confirming the possibility of the formulations to be intravenously administrated. Preliminary BBB passage tests highlighted the capability of the formulations to pass the BBB and reach the brain. Conclusions: New non-toxic, hemocompatible liposome and DCL formulations encapsulating E4 were prepared. The formulations are promising drug delivery system to target estrogens to the brain, due to their physiochemical characteristics. Aknowledgment : The authors thank Estetra SPRL for providing Estetrol. [less ▲]

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See detailLa fluidothérapie chez le bovin adulte
Lecomte, Denis; Casalta, Hélène ULg; Djebala, Salem ULg et al

Conference (2016, September 27)

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See detailGroundwater flow and saltwater intrusion modelling in the Continental Terminal (CT) aquifer near the Saloum inverse estuary in Senegal
Dieng, Ndeye Maguette ULg; Orban, Philippe ULg; Dassargues, Alain ULg et al

Conference (2016, September 27)

The Saloum River hypersaline estuary (Senegal) is an ‘inverse estuary’ showing a salinity increasing from the river mouth towards inland. This salinization process is mainly driven by a net loss of ... [more ▼]

The Saloum River hypersaline estuary (Senegal) is an ‘inverse estuary’ showing a salinity increasing from the river mouth towards inland. This salinization process is mainly driven by a net loss of freshwater due to intense evaporation. In this context, interactions between the river and the surrounding aquifer of the Continental Terminal (CT) may lead to local and progressive salinization of this groundwater main resource for water supply. Our study, based on available data and new measured data in 2012 and 2013, is focused on the southern part of the Saloum basin. It confirms that the groundwater resource is threatened by local saltwater intrusions in the vicinity of the Saloum River and along the western coastal part of the aquifer. For a long term water resources management, it is thus essential to predict the future evolution of this process in a context of increasing groundwater pumping rate together with climate variability and changes. A groundwater flow model is developed using MODFLOW. Starting from a conceptual steady-state situation corresponding to the CT aquifer state in 1973 before development of pumping, a transient calibration of the groundwater flow model is performed on data from 1974 to 2012. Despite the low number of measured data, the model can be considered as the current best assessment tool for future predictions. Using the particle tracking technique (MODPATH), a first assessment of the saltwater intrusions in the aquifer is simulated (neglecting the density effect on the hydraulic conductivity) confirming the measured data. Results, for an increased pumping of 20% in 2050 combined with different climatic scenarios, are useful to assess how the saltwater intrusions will evolve in the next years. [less ▲]

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See detailAn old slate mine as lower reservoir for UPSH (Underground Pumping Storage Hydroelectricity)- groundwater interactions and limitations
Bodeux, Sarah ULg; Pujades, Estanislao ULg; Orban, Philippe ULg et al

Conference (2016, September 27)

Renewable energy sources have an increasing role to play in the future energy framework but their intermittence cannot afford a stable production according to the demand. Pumped Storage Hydroelectricity ... [more ▼]

Renewable energy sources have an increasing role to play in the future energy framework but their intermittence cannot afford a stable production according to the demand. Pumped Storage Hydroelectricity (PSH) is an efficient technology to store and release electricity. However, the development of new PSH plants is limited by environmental and topographic constraints. An innovative alternative consists in using old underground mines as lower reservoirs of Underground Pumped Storage Hydroelectricity (UPSH) plants. In this configuration, large amount of water is pumped and injected in underground cavities and these cyclic stresses impact the groundwater system. A hybrid 3D finite element mixing cell method is used to numerically simulate the use of an UPSH facility, in the case of an abandoned slate mine. Different scenarios are computed with varying pumping injection time-sequences. In order to assess the impact on the surrounding groundwater conditions, the resulting head evolution in the cavity and at different distances is analyzed in terms of groundwater oscillation magnitude, drawdown, and seepage into the cavity. Results show clearly the influence of the pumping injection time-sequence (rates, regularity, timing and duration of no-activity periods) on the actual head evolution in the surrounding medium and consequently on the magnitude of interactions with the cavity. For a given hydraulic conductivity of the surrounding medium (i.e. slates in this case study), the main conclusion is that the resulting interaction seepage flows (in and out of the cavity) are highly dependent on the chosen pumping injection sequences. The future impact of UPSH operation must be assessed taking this fact into account. [less ▲]

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See detailOccurrence of greenhouse gases (CO2, N2O and CH4) in groundwater of the Walloon Region (Belgium)
Jurado Elices, Anna ULg; Borges, Alberto ULg; Hakoun, Vivien et al

Conference (2016, September 27)

Carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) can be indirectly transferred to the atmosphere through groundwater discharge into surface water bodies such as rivers. However, these emissions ... [more ▼]

Carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) can be indirectly transferred to the atmosphere through groundwater discharge into surface water bodies such as rivers. However, these emissions are poorly evaluated and highly uncertain. The aim of this work is identify the hydrogeological contexts (alluvial, sandstone, chalk and limestone aquifers) and in situ conditions which are most conducive to the generation and occurrence of GHGs in groundwater at a regional scale. To this end, CO2, CH4 and N2O concentrations as well as major and minor elements were monitored (n=37 samples) in two field campaigns (09/2014 and 03/2015) in 15 groundwater bodies of the Walloon Region (Belgium). This preliminary work, which was presented in the 42st IAH conference (Rome, Italy), shown that GHG concentrations range from 5,160 to 47,544 ppm from the partial pressure of CO2 and from 0 to 1,064 nmol/L and 1 to 5,637 nmol/L for CH4 and N2O respectively. Overall, groundwater was supersaturated in GHGs with respect to atmospheric equilibrium, suggesting that groundwater contribute to the atmospheric GHGs budget. A third sampling campaign is carried out in 2016 including around 60 new groundwater samples. The combination of the results of the three campaigns allows: (1) reducing the uncertainties related to indirect emissions of GHG through groundwater-surface water interaction and (2) contributing to a better understanding of the occurrence of GHGs in aquifers. New results will be presented and discussed in detail in the presentation. [less ▲]

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See detailInfluence of groundwater exchanges on the efficiency of Underground Pumped Storage Hydroelectricity plants using open pit mines
Pujades, Estanislao ULg; Bodeux, Sarah ULg; Orban, Philippe ULg et al

Poster (2016, September 27)

Underground Pumped Storage Hydropower (UPSH) plants can be used to manage the production of electrical energy according to the demand. These plants consist in two reservoirs, the upper one is located at ... [more ▼]

Underground Pumped Storage Hydropower (UPSH) plants can be used to manage the production of electrical energy according to the demand. These plants consist in two reservoirs, the upper one is located at the surface while the lower one is underground. The energy is stored by pumping water from the lower to the upper reservoir and produced by releasing water from the upper to the lower one. As a result, the hydraulic head in the lower reservoir varies continuously. UPSH plants interact with the surrounding aquifers exchanging groundwater. These groundwater exchanges, which play an important role in the evolution of the hydraulic head inside the underground reservoir, are a fact of concern in the selection of pumps and turbines because their efficiency varies with respect to the head difference between the two reservoirs. Therefore, the aquifer parameters should be considered in the selection of pumps and turbines. In this context, with an UPSH plant made up by an open pit mine, we study numerically (1) the influence of groundwater exchanges on the efficiency and (2) how the hydraulic head evolution varies depending on the aquifer properties. The relation among the groundwater exchanges, the efficiency of pumps and turbines and the aquifer parameters is considered by comparing the numerical results of several simulations. It is shown that groundwater exchanges are not negligible when optimizing the efficiency of UPSH plants. A priori, low hydraulic conductivity geological media were preferred to decrease interactions with the open-pit or the cavity used as lower reservoir. Taking into account the pump/turbine performance curves, it appears that, on the contrary, the global efficiency would be increased if the surrounding medium facilitates large groundwater exchanges because hydraulic head variations are softened. [less ▲]

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See detailClimatic and management drivers of CO2 exchanges by a production crop: Analysis over three successive 4-year crop rotation cycles
Buysse, Pauline ULg; Manise, Tanguy ULg; De Ligne, Anne ULg et al

Poster (2016, September 27)

Carbon dioxide (CO2) exchanges between crops and the atmosphere are influenced by both climatic and crop management drivers. The investigated crop, situated at the Lonzée Terrestrial Observatory (LTO ... [more ▼]

Carbon dioxide (CO2) exchanges between crops and the atmosphere are influenced by both climatic and crop management drivers. The investigated crop, situated at the Lonzée Terrestrial Observatory (LTO, candidate ICOS site) in Belgium and managed for more than 70 years using conventional farming practices, was monitored over three complete sugar beet/winter wheat/potato/winter wheat rotation cycles from 2004 to 2016. Continuous eddy-covariance measurements and regular biomass samplings were performed in order to obtain the daily and seasonal Net Ecosystem Exchange (NEE), Gross Primary Productivity (GPP), Total Ecosystem Respiration (TER), Net Primary Productivity (NPP), and Net Biome Production (NBP). Meteorological data and crop management practices were also recorded. Over the 12 years, NEE was negative (-4.34 kg C m-2) but NBP was positive (1.05 kg C m-2), i.e. as soon as carbon exportation by harvest and carbon importation (manure, slimes) are included in the budget, the site behaves as a carbon source. At the crop rotation scale (4 years) it was quite remarkable to observe that NBP was very similar over the three rotations (0.30-0.36 kg C m-2), despite climatic and management differences between years. Crop type impacted carbon exchanges, with sugar beet and winter wheat crops leading to higher net carbon sequestration than seed potato crops. For one given crop, larger growth length and cumulated global radiation drove larger cumulated NEE. Net carbon emissions were observed during intercrops, but growing mustard during these periods reduced their rates and provided carbon residues to the soil. NBP values suggest that one sixth of the total soil organic carbon stock at LTO (6.23 ± 0.16 kg C m-2 in [0, 60] cm) would be lost in 12 years. Large uncertainties (mostly due to biomass measurements) affect NBP estimates, but still, this figure is huge and should encourage cultural practices returning carbon to the soil. [less ▲]

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See detailComparison of temperature from DTS and ERT with direct measurements during heat tracer experiments in heterogeneous aquifers
Nguyen, Frédéric ULg; Hermans, Thomas ULg; Jamin, Pierre ULg et al

Conference (2016, September 27)

Geothermal field characterization and heat tracer experiments often rely on scarce temperature data collected in boreholes. Electrical resistivity tomography (ERT) and distributed temperature sensing (DTS ... [more ▼]

Geothermal field characterization and heat tracer experiments often rely on scarce temperature data collected in boreholes. Electrical resistivity tomography (ERT) and distributed temperature sensing (DTS) have the potential to provide spatial information on temperature changes in the subsurface. In this contribution, we show how DTS and ERT have been used to investigate the heterogeneity of a heterogeneous aquifer during a heat tracing experiment under forced gradient conditions. Optic fibers were installed in the heat injection well and in two piezometers intersecting the main flow directions at 8 m from the injection well. These piezometers were also equipped with ERT. The DTS measurement in the injection well clearly shows the two-layer nature of the aquifer. After the end of injection, the temperature in the bottom part of the well decreases faster than in the upper part due to the higher water fluxes. Those results are confirmed by DTS measurements in natural flow conditions during a heating wire test. DTS and ERT in the cross-panel both show the vertical and lateral heterogeneity of the aquifer. Temperatures only increase significantly in the bottom part of the aquifer where advection is predominant. However, strong differences are observed laterally. ERT additionally shows that the hot plume is divided in two main flow paths, which is confirmed by direct temperature measurements. The comparison of DTS and ERT shows that one of the well is suffering from water mixing. Indeed, temperature from DTS are homogeneous over the whole tichkness of the aquifer, whereas ERT temperature, less affected by local variations, are varying. Our study demonstrate the value of spatially distributed measurements for the monitoring of heat tracer experiment and highligths the issue of multilevel sampling. The detailed temperature measurements can be subsequently used in hydrogeological model to better estimates heat flow and transport parameters. [less ▲]

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See detailLa dynamique des profondeurs. Les réinventions de l’espace dans Alice Comedies, Oswald the Lucky Rabbit et Mickey Mouse
Tomasovic, Dick ULg

Conference (2016, September 27)

Détaillant les mises en scènes de l’espace dans trois séries essentielles de l’histoire du dessin animé (Alice Comedies (1923-1927), Oswald the Lucky Rabbit (1927-1928) et Mickey Mouse (dès 1928)) comme ... [more ▼]

Détaillant les mises en scènes de l’espace dans trois séries essentielles de l’histoire du dessin animé (Alice Comedies (1923-1927), Oswald the Lucky Rabbit (1927-1928) et Mickey Mouse (dès 1928)) comme autant d’étapes dans la définition d’une nouvelle spatialité servant au mieux les créations de personnages animés d’un nouveau type, analysant précisément certaines images dans la manière dont elles articulent avant-plan et arrière-plan, cette intervention pointe également les présupposés idéologiques du simulacre de la profondeur chez Disney. Reposant plus particulièrement sur le commentaire de quelques films emblématiques tels que Alice’s Wonderland (1923), Trolley Troubles (1927), ou Plane Crazy (1928), entre autres, l’intervention, en revenant notamment sur les contributions des spécialistes de l’histoire et de l’esthétique disneyenne (Donald Crafton, Jay P. Telotte, Leonard Maltin, J.B. Kaufman…), tente d’apporter un nouvel éclairage sur l’évolution de la conception de l’espace (en tant que problème esthétique, dramatique et psychologique) dans le dessin animé industriel américain, mais aussi, indirectement et plus largement, dans l’histoire des films d’animation. [less ▲]

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See detailDEVELOPMENT OF NOVEL CATIONIC AND LIGAND-GRAFTED ANIONIC LIPOSOMES FOR BRAIN-TARGETED DRUG DELIVERY
Karim, Reatul ULg; Palazzo, Claudio ULg; Laloy, Julie et al

Poster (2016, September 27)

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See detailUVS – JIRAM image comparison during Juno PJ1
Gérard, Jean-Claude ULg; Bonfond, Bertrand ULg; Grodent, Denis ULg et al

Conference (2016, September 27)

We present a comparison between images collected in the infrared and ultraviolet by the JIRAM and IUVS spectral imagers on board the Juno orbiter. Similarities and differences are pointed out.

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See detailGenomics and ecological adaptation: metal hyperaccumulation in Arabidopsis halleri
Hanikenne, Marc ULg

Conference (2016, September 27)

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See detailSmall molecule ligands for the orphan GPR27
Dupuis, Nadine ULg; Franssen, Delphine ULg; Laschet, Céline ULg et al

Poster (2016, September 26)

Background G protein-coupled receptors (GPCRs) are involved in many physiological processes and constitute the target of around 30% of marketed therapies. Nonetheless, ~100 human GPCRs have no known ... [more ▼]

Background G protein-coupled receptors (GPCRs) are involved in many physiological processes and constitute the target of around 30% of marketed therapies. Nonetheless, ~100 human GPCRs have no known ligand and are designated as "orphan". This project focuses on GPR27, a rhodopsin-like alpha orphan of the SREB family (Super conserved Receptors Expressed in the Brain), presumably involved in the regulation of insulin secretion [1]. Methods In order to identify small molecules activating GPR27, we developed a firefly luciferase complementation assay (based on [2]) to assess the binding of ß-arrestin2 to the activated GPCR. To increase the affinity for and strengthen the interaction with ß-arrestin2, a GPR27-V2R chimera has been used for library screening. Results Small molecules activating GPR27-V2 have been identified in the DiverSetTM library (ChemBridge). After exclusion of non-specific activities using another unrelated GPCR, two compounds sharing a common scaffold with activity in the low micromolar range were selected for further investigations. We confirmed their agonist profile by performing complete concentration-response curves on our arrestin complementation assay as well as orthogonal assays. These compounds show good specificity being inactive on GPR85-V2 and GPR173-V2 (the two other SREB members). With these original tools, we characterized the recruitment of ß-arrestin2 to activated GPR27 WT. Conclusion We identified small molecule ligands for GPR27 that will serve as valuable tools for studying the pharmacology of GPR27 as well as its physiological roles, for example in insulin secretion. 1 Ku G.M., Pappalardo Z., Luo C.C., German M.S., McManus M.T. An siRNA Screen in Pancreatic Beta Cells Reveals a Role for Gpr27 in Insulin Production. PLoS genetics. 2012, 8, e1002449. 2 Takakura H., Hattori M., Takeuchi M., Ozawa T. Visualization and Quantitative Analysis of G Protein-Coupled Receptor−β-Arrestin Interaction in Single Cells and Specific Organs of Living Mice Using Split Luciferase Complementation. ACS Chem. Biol. 2012, 7, 901−910. [less ▲]

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See detailAssessing the impact of climate change on terrestrial plants in Europe using a Dynamic Vegetation Model driven by EURO-CORDEX projections
Dury, Marie ULg; Hambuckers, Alain ULg; Henrot, Alexandra-Jane ULg et al

Poster (2016, September 26)

While the combination of warmer and drier mean climatic conditions can have severe impacts on ecosystems, extreme events like droughts or heat waves that break the gradual climate change can have more ... [more ▼]

While the combination of warmer and drier mean climatic conditions can have severe impacts on ecosystems, extreme events like droughts or heat waves that break the gradual climate change can have more long-term consequences on ecosystem composition, functioning and carbon storage. Hence, it is essential to assess the changes in climate variability and the changes in frequency of extreme events projected for the future. Here, the process-based dynamic vegetation model CARAIB DVM was used to evaluate and analyse how future climate and extreme events will affect European terrestrial plants. To quantify the uncertainties in climatic projections and their potential impacts on ecosystems, the vegetation model was driven with the outputs of different regional climatic models, nested in CMIP5 GCM projections for the EURO-CORDEX project: ALADIN53 (Météo-France/CNRM), RACMO22E (KNMI), RCA4 (SMHI) and REMO2009 (MPI-CSC) RCMs. These daily climatic scenarios are at a high spatial resolution (0.11°, ≈ 12 km). CARAIB simulations were performed across Europe over the historical period 1971-2005 and the future period 2006-2100 under RCP4.5 and RCP8.5 emission scenarios. We simulated a set of 99 individual species (47 herbs, 12 shrubs and 40 trees) representing the major European ecosystem flora. First, we analysed the climatic variability simulated by the climatic models over the historical period and compared it with the observed climatic variability. Then, we evaluated change in climatic variability and extreme events projected by the climatic models for the end of the century. Finally, we assessed the change in species productivity and abundance. We evaluated the severity of projected productivity change for the period 2070-2099 relative to their current productivity variability (period 1970-1999). Mean changes were considered severe if they exceed observed variability. The projections of potential shifts in species distributions are directly dedicated to current forest management. [less ▲]

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See detailRobust mission design using invariant manifolds
Dell'Elce, Lamberto ULg; Baresi, Nicola; Kerschen, Gaëtan ULg et al

in Proceedings of the 67th International Astronautical Congress (2016, September 26)

Uncertainties in the dynamical system affect all real-life applications in astrodynamics. This is particularly true for satellites orbiting about small bodies owing to their irregular shapes and to the ... [more ▼]

Uncertainties in the dynamical system affect all real-life applications in astrodynamics. This is particularly true for satellites orbiting about small bodies owing to their irregular shapes and to the difficulties in characterizing their physical properties at the early stages of a dedicated spacecraft mission. Hence, accommodating uncertainty in the orbital design process may be extremely beneficial for the success of the mission. Here, in a Lyapunov stability perspective, the properties of the invariant manifolds are exploited to generate regions of the phase space where the motion is guaranteed to evolve despite the uncertainties in the system parameters and navigation errors. Specifically, the scenario approach is applied to tackle a semi-infinite optimization problem that locates these robust regions. The methodology is illustrated with the robust design of a inner retrograde orbit about the primary of (65803) Didymos as well as with a ballistic landing on the smaller secondary body. [less ▲]

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See detailQuelles réponses face à la fatigue vocale? Variabilité inter-individuelle des modifications acoustiques de la voix au cours de la journée
Remacle, Angélique ULg; Gerber, Silvain; Garnier, Maëva

Poster (2016, September 26)

Objectifs: 1) décrire l’évolution de 4 indicateurs acoustiques de la fatigue vocale au cours d’une journée de travail et examiner leur universalité dans l'échantillon, 2) déterminer si différentes ... [more ▼]

Objectifs: 1) décrire l’évolution de 4 indicateurs acoustiques de la fatigue vocale au cours d’une journée de travail et examiner leur universalité dans l'échantillon, 2) déterminer si différentes typologies de réponse à la fatigue vocale peuvent être distinguées. Population: 22 enseignantes enregistrées le matin et le soir après leur journée de travail, à 3 temps de l’année: octobre, décembre, et février. Tâche: voyelle [a] tenue produite 5 fois à intensité et fréquence confortables. Paramètres mesurés avec Praat et moyennés sur les 5 répétitions: F0 (Hz), rapport harmoniques/bruit (HNR, dB), local Jitter (%), et local Shimmer (%). Les variations des moyennes entre le soir et le matin (Δ) sont calculées pour chaque paramètre. Résultats: En accord avec la littérature, le Δ moyen pour les 22 participantes aux 3 temps montre une augmentation de F0 et HNR, et une diminution de Jitter et Shimmer au cours de la journée. Cependant, ces résultats ne sont pas généralisés dans notre échantillon. Une analyse hiérarchique ascendante permet d'identifier 3 typologies de réponse à la fatigue vocale, observées suite à la journée de travail. Typologie 1: tendance inverse à la littérature (ΔF0 et ΔHNR négatifs, Δjitter et Δshimmer positifs). Comportement hypofonctionnel en réponse à la fatigue vocale. Typologie 2: tendance et amplitude similaires à la littérature (ΔF0 et ΔHNR positifs, Δjitter et Δshimmer négatifs). Réponse attendue, adaptation saine à la fatigue vocale. Typologie 3: tendance similaire à la littérature mais d’amplitude très marquée. Comportement hyperfonctionnel, suspicion d’un trouble vocal. [less ▲]

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See detailLaboratory diagnosis of syphilis
HUYNEN, Pascale ULg

Conference (2016, September 26)

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See detailGroundwater flow and saltwater intrusion modelling in the Continental Terminal (CT) aquifer near the Saloum inverse estuary in Senegal
Faye, Serigne; Ndeye, Maguette Dieng; Orban, Philippe ULg et al

Conference (2016, September 26)

The Saloum River hypersaline estuary (Senegal) is an ‘inverse estuary’ showing a salinity increasing from the river mouth towards inland. This salinization process is mainly driven by a net loss of ... [more ▼]

The Saloum River hypersaline estuary (Senegal) is an ‘inverse estuary’ showing a salinity increasing from the river mouth towards inland. This salinization process is mainly driven by a net loss of freshwater due to intense evaporation. In this context, interactions between the river and the surrounding aquifer of the Continental Terminal (CT) may lead to local and progressive salinization of this groundwater main resource for water supply. Our study, based on available data and new measured data in 2012 and 2013, is focused on the southern part of the Saloum basin. It confirms that the groundwater resource is threatened by local saltwater intrusions in the vicinity of the Saloum River and along the western coastal part of the aquifer. For a long term water resources management, it is thus essential to predict the future evolution of this process in a context of increasing groundwater pumping rate together with climate variability and changes. A groundwater flow model is developed using MODFLOW. Starting from a conceptual steady-state situation corresponding to the CT aquifer state in 1973 before development of pumping, a transient calibration of the groundwater flow model is performed on data from 1974 to 2012. Despite the low number of measured data, the model can be considered as the current best assessment tool for future predictions. Using the particle tracking technique (MODPATH), a first assessment of the saltwater intrusions in the aquifer is simulated (neglecting the density effect on the hydraulic conductivity) confirming the measured data. Results, for an increased pumping of 20% in 2050 combined with different climatic scenarios, are useful to assess how the saltwater intrusions will evolve in the next years. [less ▲]

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See detailMUCOADHESIVE SPONGES WITH PEGYLATED LIPOPLEXES: TOWARDS A SUSTAINED VAGINAL DELIVERY OF siRNA
Furst, Tania ULg; Dakwar, Georges; zagato, Elisa et al

Poster (2016, September 26)

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See detailRelectures de La Misère du monde: Bourdieu, Sartre, Enzensberger
Cormann, Grégory ULg

Conference (2016, September 26)

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See detailReprise et renouvellement de la philosophie sartrienne dans le champ des sciences sociales
Recchia, Fabio ULg

Conference (2016, September 26)

L'objectif de cette communication est double. D'une part, il s'agit de définir ce que le projet sartrien d'une anthropologie structurelle et historique emprunte au structuralisme français. Nous porterons ... [more ▼]

L'objectif de cette communication est double. D'une part, il s'agit de définir ce que le projet sartrien d'une anthropologie structurelle et historique emprunte au structuralisme français. Nous porterons ainsi notre attention sur le numéro 246 de la revue "Les Temps Modernes", où Sartre (mais aussi Bourdieu et le jeune Maurice Godelier) met en question les principes fondamentaux de l'analyse structurale. D'autre part, nous souhaitons préciser en quoi la philosophie du second Sartre revisite en profondeur ces principes. Nous mobiliserons, pour ce faire, "Les Racines de l'éthique". Récemment édité dans "Les Études sartriennes", cet inédit de l'oeuvre sartrienne précise la stratégie par laquelle celle-ci entend conserver mais aussi dépasser les apories de l'analyse structurale. Aussi la problématique générale de notre communication consiste-t-elle à documenter le rapport qu'entretînt la philosophie sartrienne à l'égard d'un certain segment des sciences sociales françaises. À cette fin, nous étudierons l'activité éditoriale des "Temps Modernes", ainsi que celle qui fut générée postérieurement par le champ des "Études sartriennes". [less ▲]

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See detailLe développement de l’agriculture familiale par les transferts des migrants
Yao Namé, Juste Michel ULg; Lebailly, Philippe ULg

Conference (2016, September 25)

The following pages report the results of our survey conducted among (Malian, Senegalese and Mauritanian) Soninké migrants during the period of 14th to 4 December 2015, living in the social residences of ... [more ▼]

The following pages report the results of our survey conducted among (Malian, Senegalese and Mauritanian) Soninké migrants during the period of 14th to 4 December 2015, living in the social residences of the former home Pinel (first home of migrant workers in France). This survey had to aim to discuss the implementation and use of a new tool to transfer the money in order to reduce use of informal channels, to promote financial inclusion, to finance smallholding and to develop entrepreneurship in rural by granting of credits medium or long term via Microfinance Institutions (IMF). [less ▲]

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See detailDysregulated circulating miRNAs in pre-eclampsia
Tebache, Linda; Munaut, Carine ULg; Blacher, Silvia ULg et al

Conference (2016, September 25)

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See detailAnalyse comparative des coûts de production rizicole dans les pays de la Communauté Economique des Pays des Grands Lacs (CEPGL).
Furaha Mirindi, Germaine ULg; Lebailly, Philippe ULg

Conference (2016, September 23)

Cet article fait une analyse comparative des résultats économiques de la production rizicole durant la saison B 2014 dans les trois pays de la CEPGL qui sont la République Démocratique du Congo, le Rwanda ... [more ▼]

Cet article fait une analyse comparative des résultats économiques de la production rizicole durant la saison B 2014 dans les trois pays de la CEPGL qui sont la République Démocratique du Congo, le Rwanda et le Burundi. L’approche comparative permet de trouver les explications des différences des résultats en partie dans les politiques mises en œuvre dans chaque pays. Les enquêtes ont été menées dans la plaine de la Ruzizi partagée entre les trois pays auprès de 240 producteurs du riz choisi à partir de la méthode des quotas sur la base d'une stratification des exploitations rizicoles. Dans le site congolais (où il est plus difficile d’accéder aux intrants et crédits), les coûts de production d’1kg de paddy sont les plus élevés avec une fonction de production y=0,034x+0,053z+0,422 et le rendement le plus bas (2698kgs). Par contre, dans les sites burundais et rwandais où l’Etat intervient dans l’approvisionnement en intrants et particulièrement dans le site rwandais, l’accès aux crédits, les fonctions de production sont respectivement de y=0,024x+0,031z+0,297 et y=0,017x+0,023z+0,269 avec des rendements de 3962kgs et 5339kgs dans le même ordre. Les coûts de production supportés sur un hectare rizicole ou encore pour la production d’une tonne de paddy varient selon le pays car ils dépendent de la valeur des intrants utilisés et des autres charges de structures. Ils varient ainsi de 1139,4USD à 1354,5USD/ ha et de 269 à 422USD/tonne. [less ▲]

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See detailUn morso di più: ecologia del cannibalismo in Salamandra salamandra
Melotto, Andrea; Manenti, Raoul; Ficetola, Francesco et al

Conference (2016, September 23)

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See detailApplications des relevés 3D au patrimoine, de l'acquisition au système d'information 3D
Hallot, Pierre ULg; Billen, Roland ULg; Poux, Florent ULg et al

Conference (2016, September 23)

Les techniques permettant l’acquisition 3D du patrimoine bâti sont maintenant assez mures et démocratiques pour être utilisées à grande échelle. De plus en plus d’édifices font l’objet d’une sauvegarde ... [more ▼]

Les techniques permettant l’acquisition 3D du patrimoine bâti sont maintenant assez mures et démocratiques pour être utilisées à grande échelle. De plus en plus d’édifices font l’objet d’une sauvegarde numérique sous la forme de nuages de points colorés. Il reste néanmoins de nombreux défis à relever notamment pour : harmoniser les pratiques d’acquisition en terme de qualité et de précision, assurer l’interopérabilité entre les jeux de données ; exploiter pleinement l’information ponctuelle collectée ; et proposer une visualisation adéquate de ces grands jeux de données. Dans le cadre des développements réalisés à l’Unité de Géomatique de l’ULg, nous travaillons à la mise au point de systèmes d’informations permettant d’assurer un lien entre les informations sémantiques issues des applications archéologiques, architecturales, d’histoire de l’art avec les modèles 3D réalisés. La mise en place de ces systèmes d’informations passe par plusieurs étapes de recherche relatives à la sectorisation automatique, les structures de données, la définitions d’ontologies thématiques et finalement les règles sémiologiques de représentations dans un environnement virtuel 3D. Au cours de cette présentation, nous proposons de parcourir trois projets de recherche en cours au sein de l’Unité afin l’illustrer nos propos. Nous présenterons plus particulièrement le cas de la cathédrale Saint-Paul de Liège. [less ▲]

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See detailPhosphate-based composite electrodes for Li/Na-ion batteries: upscalable solution syntheses with in-situ solid carbon addition
Vertruyen, Bénédicte ULg; Brisbois, Magali; Eshraghi, Nicolas ULg et al

Conference (2016, September 22)

Since the success story of lithium iron phosphate, other phosphate-based compounds have attracted a lot of interest as promising candidates for positive electrodes in lithium-ion or sodium-ion batteries ... [more ▼]

Since the success story of lithium iron phosphate, other phosphate-based compounds have attracted a lot of interest as promising candidates for positive electrodes in lithium-ion or sodium-ion batteries. Their electronic conductivity usually has to be improved through the preparation of composite powders ensuring intimate contact between the active material and conductive carbon. We report on the one-step synthesis of composite precursors using spray-drying or hydrothermal synthesis routes, two techniques which offer easy scaling-up of production. We show that addition of a solid carbon source (carbon black or carbon nanotubes) into the solution has a strong influence on the powder microstructure and is very effective in improving the battery cycling performance, taking our recent results on phosphates [Fex(PO4)(OH)y.zH2O)] and fluorophosphates [Na2FePO4F, Na3V2(PO4)2F3] as examples. We also compare this approach with the addition of the carbon source as a soluble precursor (such as ascorbic acid or citric acid) where the in situ formation of carbon is achieved by a heat treatment in inert atmosphere (typically argon). [less ▲]

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See detailInfluence d'un programme de revalidation multidisciplinaire post-cancer du sein sur la fonction physique
Leclerc, Anne-France ULg; Foidart-Dessalle, Marguerite ULg; BURY, Thierry ULg et al

in 9ème Congrès commun SFMES - SFTS : Abstract book (2016, September 22)

Objectif : Le cancer du sein ainsi que ses traitements sont à l'origine de nombreux effets secondaires indésirables, notamment sur la fonction physique. Cette étude a pour objectif de déterminer les ... [more ▼]

Objectif : Le cancer du sein ainsi que ses traitements sont à l'origine de nombreux effets secondaires indésirables, notamment sur la fonction physique. Cette étude a pour objectif de déterminer les bénéfices éventuels d’un programme de revalidation multidisciplinaire sur la santé physique des femmes ayant été traitées pour un cancer du sein et d'évaluer l'influence de certaines caractéristiques individuelles initiales sur la réponse du groupe expérimental au programme de revalidation. Matériel et méthodes : L'étude constitue un essai clinique contrôlé non-randomisé évaluant une population totale de 209 patientes, recrutées sur base du volontariat et réparties en deux groupes, soit un groupe contrôle (n = 106) et un groupe expérimental (n = 103). Ce dernier a bénéficié d’une revalidation de trois mois comprenant un entraînement physique supervisé à raison de trois séances par semaine et diverses sessions psycho-éducatives. Pour l'ensemble des participantes, des évaluations constituées d'une part de mesures physiques et fonctionnelles et d'autre part de mesures de composition corporelle ont été programmées à 0 et 3 mois. Celles-ci ont inclus un test de souplesse ("Sit and Reach"), un test d'effort maximal sur bicyclette ergométrique avec suivi cardio-respiratoire, un test de marche de six minutes et la mesure de l'indice de masse corporelle et du pourcentage de graisse corporelle. Afin d'affiner l'analyse, trois groupes ont également été constitués au sein du groupe expérimental à partir des caractéristiques individuelles de thérapie adjuvante (présence de chimiothérapie ou non), de chirurgie (mastectomie ou tumorectomie) et de délai de fin de traitement (délai ≤ 4 mois ou ≥ 8 mois). Résultats : Initialement, toutes les patientes présentent un état de déconditionnement physique, non influencé par le délai de fin de traitement ou par le type de chirurgie, mais bien influencé par la présence d'une chimiothérapie puisque la VO2max apparaît significativement plus faible dans ce cas. Au terme des trois mois, la souplesse (p < 0,0001), la consommation maximale d'oxygène (p < 0,0001), la puissance maximale aérobie (p < 0,0001) et la distance de marche en six minutes (p < 0,0001) s’améliorent significativement au sein du groupe expérimental. Au sein du groupe contrôle, aucune amélioration n'est constatée, excepté pour la distance de marche (p = 0,0031). Par ailleurs, une augmentation significative de l'indice de masse corporelle (p = 0,034) et du pourcentage de graisse corporelle (p = 0,034) est observée au sein du groupe contrôle alors que ce paramètre diminue significativement au sein du groupe expérimental (p = 0,037). Enfin, toutes les patientes du groupe expérimental présentent un même profil de progression quelles que soient leurs caractéristiques individuelles initiales. Conclusion : Cette étude démontre ainsi les effets bénéfiques, tant sur le plan physique que de la composition corporelle, d’une prise en charge multidisciplinaire chez des femmes ayant été traitées pour le cancer du sein. [less ▲]

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See detailPropriétés multifractales de la divergence de séries d’ondelettes
Esser, Céline ULg

Conference (2016, September 22)

Dans cet exposé, nous nous intéressons à la divergence ponctuelle de séries d'ondelettes dans un espace de Besov donné. Nous obtenons une borne supérieure pour la dimension de Hausdorff de l'ensemble des ... [more ▼]

Dans cet exposé, nous nous intéressons à la divergence ponctuelle de séries d'ondelettes dans un espace de Besov donné. Nous obtenons une borne supérieure pour la dimension de Hausdorff de l'ensemble des points ayant un taux de divergence donné, et nous montrons que cette borne est optimale en utilisant les notions de résidualité et de prévalence. [less ▲]

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See detailGAVRAY Claire (2016) The evolution of boys’ and girls’ attitudes and moods at the light of their historical opportunities : the case of violence and depression -
Gavray, Claire ULg

Conference (2016, September 22)

depression mood and violent behaviour are linked as a common dynamic amongst female teenargers but not amongst male ones ( twho different paths for them). The roots of depression and violence are ... [more ▼]

depression mood and violent behaviour are linked as a common dynamic amongst female teenargers but not amongst male ones ( twho different paths for them). The roots of depression and violence are connected to gender socialisation (importance of lack of recognition and negative life events in private sphere for girls and in public sphere for boys). [less ▲]

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See detailGlucose production: influence of the datasets choice on LCA results
Gerbinet, Saïcha ULg; Belboom, Sandra ULg; Léonard, Angélique ULg

Poster (2016, September 22)

The aim of this study is to have a good understanding of the environmental impact of glucose production. Glucose is generally produced from corn or wheat. Since agricultural processes are known to be ... [more ▼]

The aim of this study is to have a good understanding of the environmental impact of glucose production. Glucose is generally produced from corn or wheat. Since agricultural processes are known to be difficult to evaluate by LCA, the results obtained with two different LCA databases, Gabi and EcoInvent, are compared in this work. The production of glucose from raw materials can be divided in two steps: the agricultural step allowing the plant production, and the conversion step including the extraction of the starch from the plant and its hydrolysis into glucose. Preliminary results underline the high impact of the agricultural step, so a special attention has been paid to these data. Specific Belgian data collected by the Walloon Agricultural Research Centre (CRA-W) (2014) [1] have been used as primary data (yield, amount of fertilizers, etc.), either using EcoInvent or Gabi datasets background data to model fertilizers, diesel consumption, etc. A third model was built using only data available in Ecoinvent for corn and wheat cultures. For the conversion step, literature data have been used along with some industrial data. As few studies are available in the literature concerning starch hydrolysis, the focus has been placed on data validation (mass balance checks, cross-reference information, etc.). Based on these multiple sources, it is possible to compare the LCA results for the production of 1 kg of glucose for three different cases, summarized in the following table. Table 1: Summary of modelled cases Agricultural step Conversion steps Primary data Dataset Primary data Dataset Case 1 Belgian GaBi Literature + Industry GaBi Case 2 Belgian Ecoinvent Literature + Industry Ecoinvent Case 2 Ecoinvent Literature + Industry Ecoinvent The results obtained using these three models will be presented, at both the inventory and impact assessment steps. They show significant differences and highlight the need to understand in depth the involved assumptions when developing the datasets, in addition to the ones adopted for the inventory. [less ▲]

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See detailCompetition of phonon and magnon effects in the temperature dependence of spinwave stiffness
Ostler, Thomas ULg; Verstraete, Matthieu ULg; Di Gennaro, Marco ULg et al

Conference (2016, September 21)

Magnons are the elementary magnetic excitations in ordered solids. Understanding such collective excitations is important for a number of technologically relevant fields, such as, magnonics [1] or spin ... [more ▼]

Magnons are the elementary magnetic excitations in ordered solids. Understanding such collective excitations is important for a number of technologically relevant fields, such as, magnonics [1] or spin caloritronics [2]. The central interactions in spin caloritronics are the couplings of phonons with electrons and spin degrees of freedom. Furthermore, understanding the effects of temperature on the phonon and spin degrees of freedom adds a further complexity. In the present work we have developed a multiscale model of ferromagnetic materials and demonstrate the effect of temperature dependent phonon displacements on the magnons spectra. Our results show that the for Fe and Ni the effect of phonon displacements acts to reduce the Curie temperature, whereas for Permalloy the opposite is true due to an increased long-ranged exchange interaction. This increased exchange interaction results in an increasing spin-wave stiffness with increasing temperature, overcoming the usual decrease due to magnon softening. To determine the effects of increasing the phonon temperature we have developed a multiscale model whereby we begin by calculating the thermal displacement of phonons, $\sqrt{\langle u^2(T) \rangle}$, calculated using the phonopy software package [3] using electronic ground state and phonon properties determined using the ABINIT software package [4]. Then the exchange constants are determined using the SPRKKR package [5]. Finally, we use linear spin wave theory to determine the effect of the phonon temperature on the exchange alone, demonstrating an increasing frequency of the acoustic magnon branch. We take into account the thermal effects of the magnetic system through the use of the atomistic spin dynamics approach. Magnon softening due to thermal effects demonstrates a more modest increase in the exchange stiffness (over the purely phononic effect), however, an overall increase is still observed. \newline \newline [1] A. V. Chumak, V. I. Vasyuchka, A. A. Serga, and B. Hillebrands, Nature Physics, {\bf 11}, 453–461 (2015). \newline [2] G. E. W. Bauer, E. Saitoh, and B. J. van Wees, Nature Materials {\bf 11}, 391 (2012). \newline [3] Atsushi Togo and Isao Tanaka, Scr. Mater., {\bf 108}, 1-5 (2015) \newline [4] X. Gonze \textit{et al.} Computer Physics Communications {\bf 180}, 2582-2615 (2009). \newline [5] T. Huhne \textit{at al.} Physical Review B, {\bf 58}, 10236 (1998). [less ▲]

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See detailDie Familie von Medem. Zur Verbindung von Bildung, Literatur und Politik in Kurland
Leyh, Valérie ULg

Conference (2016, September 21)

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See detailThe role of meetings in building modern organisational governance systems - outlining a sociological approach to meetings
Thunus, Sophie ULg

Conference (2016, September 21)

By relying on empirical and micro level analyses of the implementation of a Belgian reform of mental healthcare delivery, this paper shows that inter-organisational and interinstitutional meetings might ... [more ▼]

By relying on empirical and micro level analyses of the implementation of a Belgian reform of mental healthcare delivery, this paper shows that inter-organisational and interinstitutional meetings might be conceived as key sites for the realisation of public policy objectives; i.e. sites where both the meaning of policy objectives and the social systems through which they are enacted are (re)defined. This paper is based on a case study on the implementation process of the ongoing Belgian reform of mental healthcare delivery, called “Reform 107”. Reform 107 is designed to shift mental healthcare organisation from the model of residential psychiatry, which is centred on medical hospital care, to community psychiatry that implies, instead, psychosocial home and/or ambulatory care. Policymakers conceived this shift through the development of local mental healthcare networks, which are defined as concrete partnerships between local, residential and ambulatory care providers and social and employment public services. The first stage in the implementation process consisted in four-year exploratory projects through which local actors were expected to refine the community care model proposed by policymakers. By asking local actors to participate in the adaptation of the model to local realities, policymakers intended to improve their own knowledge of local mental healthcare systems on the one hand, and to interest local actors in a reform that challenges their institutional interests on the other. Our analyses of the implementation of Reform 107 focused on three local exploratory projects and their monitoring by federal public health authorities. The empirical material was collected through semi-structured interviews (N=62) with policymakers and local actors, direct observations of the meetings between local mental health practitioners responsible for the reform’s implementation (N=65) and documentary analyses, including policy and (local) organisational documents. This material was first analysed by relying on a sociological frame of analysis based on the French sociology of organisations (Friedberg, 1997) and the interactionist sociology (Abbott, 2005; Bucher & Strauss, 1961; Corbin & Strauss, 2008). The resulting sociological account (Thunus, 2015) stressed that local models of governance, power struggles as well as professional knowledge significantly impacted on the development of mental healthcare networks. It also highlighted the use of new techniques by federal public health authorities to manage the reform implementation. Those techniques, including the multiplication of meetings with local actors, direct coaching of local projects’ leaders as well as training of front-line mental health professionals, were conceived as means to oppose strategies of resistance usually enacted by psychiatric hospitals (S Thunus & Schoenaers, 2012). This paper offers to refine this analysis by focusing on the specific role played by meetings in policy implementation, based on a conception of “the practice of policy-making”(Richard Freeman, Griggs, & Boaz, 2011). It draws on the observation that, though researches on policy implementation increasingly evoke meetings as part of the policy process, they do not properly address the role played by meeting in influencing, orienting and possibly (re)defining policy reforms. Indeed, following the recognition of the need for dealing with complex and uncertain problems, or wicked problems (Roberts, 2000), by relying on procedural policy instruments (Howlett, 2000) and collaborative governance (Emerson, Nabatchi, & Balogh, 2011), numerous researches focused on policy networks, hybrid forums (Callon, Lascoumes, & Barthes, 2001) and special committees whose activities involve meetings. However, by considering meetings as a part of/a tool for larger processes as problems solving, crisis resolution or decision-making, those researches made them unproblematic means to achieve predefined and external objectives. The problems resulting from a “meetings as a tool approach” (Schwartzman, 1989) are twofold. On the one hand, it seems to ignore that, by bringing different and specialised expertise together, meetings induce social, cognitive and technical challenges. Those challenges, including the sharing of specialised knowledge and harsh negotiations between actors defending institutional interests and professional jurisdictions, make meetings conflicting and problematic arenas (Cohen, March, & Olsen, 1972). On the other, when conceived as rational means to reach external objectives, meetings often appear as disappointing and pointless. Based on this observation, Schwartzman (1989) proposed to stop seeing meeting as part of larger processes as decision-making (as a tool), to focus on what meetings actually do to the organisation or social context in which they take place (i.e. to consider meetings as a topic). By drawing on Schwartzman’s invitation to make meetings a research topic, we propose to ask the question of what inter-organisational and interinstitutional meetings actually did to the Belgian mental health care reform. We suggest addressing that question by relying on a conception of policy-making as a practice of a special kind (R Freeman, Griggs, & Boaz, 2011). This conception insists on the role played by policy practices as meeting and talks in determining policy objectives and creating groups supporting them. Accordingly, we will focus on social actions and interactions unfolding through meetings and talks, to see how they use and produce knowledge, instruments and relationships both embodying and reshaping their environment. Finally, by inviting us to bracket the explicit objectives of the observed meetings (e.g. providing policymakers with an operational definition of care functions included in the proposed community model), this approach will enable us to see what inter-organisational and interinstitutional meetings actually do to policy reforms. That is, generating performances (Goffman, 1959) supporting collective enactments of new social and professional roles and artefacts that (re) constitute the meaning of the reform and the associated social system. Viewing meeting as a concrete policy practice thus helps to stress that they contribute to durable and deep change in their social environment, precisely by generating talks that largely exceed/displace their explicit mandate. [less ▲]

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See detailRelationships between mind-wandering, personal goals processing, and future thinking.
Stawarczyk, David ULg; D'Argembeau, Arnaud ULg

Conference (2016, September 20)

Mind-wandering refers to the occurrence of thoughts whose content is both decoupled from stimuli present in the immediate environment and unrelated to the task currently being carried out. Although this ... [more ▼]

Mind-wandering refers to the occurrence of thoughts whose content is both decoupled from stimuli present in the immediate environment and unrelated to the task currently being carried out. Although this phenomenon has been the object of increasing interest from the scientific community during le last decade, proportionally few studies have attempted to clearly determine the form, content, and possible functions of this particular kind of cognitions. In this presentation, we will review recent evidence from studies mainly performed in our lab suggesting that most instances of mind-wandering refer to the anticipation and planning of future events and are also closely related to the processing of personal goals. More specifically, we will first discuss the findings from behavioral research that examined the phenomenological features of mind-wandering with the use of experience sampling procedures during laboratory tasks. Results of these studies mainly revealed that most of reported mind-wandering episodes are temporally oriented towards the future and that this ‘prospective bias’ can be increased when participants’ attention had been oriented toward their personal goals prior to performing the tasks. We will next review the results of neuroimaging studies that investigated the neural correlates of mind-wandering and we will more specifically focus on meta-analytic evidences suggesting that the neural correlates of mind-wandering strongly overlap with those associated with episodic future thinking and personal goal processing. Together, these results suggest that mind-wandering may have an important adaptive value and could in particular play a key role in planning and preparing for upcoming events related to the individuals’ personal goals. [less ▲]

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See detailStudy on contribution of lipids towards the mechanical properties of milk fat globule membrane monolayer
Malik, Priyanka ULg; Danthine, Sabine ULg; Blecker, Christophe ULg

Conference (2016, September 20)

Milk fat globule membrane (MFGM) stabilizes fat globule in milk in form of emulsion. The primary monolayer of MFGM is rich in proteins and secondary bilayer is rich in polar lipids. MFGM finds application ... [more ▼]

Milk fat globule membrane (MFGM) stabilizes fat globule in milk in form of emulsion. The primary monolayer of MFGM is rich in proteins and secondary bilayer is rich in polar lipids. MFGM finds application as an additive in dairy and food industry (e.g. emulsions, infant formulas & reduced-fat products) for its emulsifying and stabilizing properties. MFGM received much attention in recent years due to both its health- beneficial & technological functionalities. This work has been carried out with the objective to understand contribution of various components towards the surface properties of complete MFGM. MFGM was isolated from fresh raw cream. During isolation of MFGM apart from polar lipids and MFGM proteins, neutral lipids are also isolated which have their origin in fat globules but are often considered as a constituent of MFGM. The MFGM was further fractioned into lipid fraction, defatted fraction and polar lipids. The mechanical properties of monolayer were studied for the above fractions using Langmuir film balance. Study of surface properties can also be linked to their techno-functional properties by calculating film elasticity of the compression isotherm which can be linked to emulsifying and stabilizing properties. The analysis of compression isotherms revealed that film elasticity is highly influenced by polar lipids. The behaviour of the MFGM appeared to be influenced by neutral lipid and defatted fraction during beginning of compression and by polar lipids at the end of compression. [less ▲]

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See detailValorization of Seeds from Some Field Border Flowering Seeds
Paul, Aman ULg; Danthine, Sabine ULg; Mutwale Kapepula, Paulin ULg et al

Poster (2016, September 20)

Flowering strips are now being increasingly cultivated along the fields to improve biodiversity. However after serving for the desired function, these plants have no utilization besides animal feed. It ... [more ▼]

Flowering strips are now being increasingly cultivated along the fields to improve biodiversity. However after serving for the desired function, these plants have no utilization besides animal feed. It could be really interesting to valorize some commonly grown plant in these strips to render food or health promoting compounds. With this objective in mind the seeds of Achillea millefolium, Anthriscus sylvestris and Prunella vulgaris were investigated for lipids, proteins and phenolic content. Further the lipids were analyzed for fatty acid profile using gas chromatography and the phenolic compounds in the methanolic extract of defatted seeds were identified using HPLC-DAD. The antiradical activity of the methanolic extracts obtained from defatted seeds was investigated using DPPH and ABTS assays. The anti-inflammatory potential of these seed extracts was evaluated on the reactive oxygen species (ROS) production by stimulated neutrophils and on the specific activity of myeloperoxidase (MPO), a pro-oxidant enzyme marker of inflammation. Seeds from all three plants were analyzed with interesting levels of lipids, proteins and phenolic content. Linoleic acid, oleic acid and alpha-linolenic acid were the major fatty acids analyzed in A. millefolium, A. sylvestris and P. vulgaris respectively. On the other hand different phenolic acid formed the major phenolic constituents. Seed extracts displayed high ABTS and DPPH radical-scavenging activities in a dose dependent manner. Also a strong dose dependent anti-inflammatory activity of all three extracts was observed against ROS production by neutrophils and MPO activity. Results indicate that these seed show a great potential to render lipids which could be utilized as human food, further the defatted seeds could be directly included in human diet due to interesting levels of proteins and anti-inflammation ability. [less ▲]

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See detailRaffinement de l'estimation asymptotique de l'exposant de Hölder
Kleyntssens, Thomas ULg; Nicolay, Samuel ULg

Conference (2016, September 19)

Dans cet exposé, nous proposons une nouvelle approche basée sur les ondelettes (via les espaces Snu) permettant d'étudier plus finement la régularité Höldérienne d'une fonction

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See detailImpact du nombre d’alternatives lors d’une tâche de reconnaissance à choix-forcé sur les processus de reconnaissance dans le vieillissement normal
Simon, Jessica ULg; Gilsoul, Jessica ULg; Bastin, Christine ULg

Poster (2016, September 19)

Les tâches de reconnaissance à choix forcé sont classiquement utilisées pour évaluer la mémoire de reconnaissance. Cependant, aucune étude n’a spécifiquement investigué l’impact du nombre d’alternatives ... [more ▼]

Les tâches de reconnaissance à choix forcé sont classiquement utilisées pour évaluer la mémoire de reconnaissance. Cependant, aucune étude n’a spécifiquement investigué l’impact du nombre d’alternatives sur les performances mnésiques des participants âgés. Nous voulons déterminer, d’une part, si le nombre d’alternatives proposées - deux ou trois – et d’autre part, si le degré de similarité entre la cible et ses leurres ont un impact sur les stratégies de récupération mises en place au cours de la tâche. Pour ce faire, nous avons recruté 20 participants jeunes et 20 participants âgés. Lors de la tâche de reconnaissance, nous leur avons demandé de choisir, parmi deux ou trois photographies de visages, celui qui a été présenté précédemment. Certains couples cibles-leurres étaient plus similaires que d’autres (partage de 60% de caractéristiques communes, contre 40%). Pour chaque item sélectionné, les participants devaient expliquer ce qui a guidé leur choix. Les premières analyses (ANOVA à mesures répétées 2 (groupes) x 2 (alternatives) x 2 (similarité) sur les deux dernières mesures, p<0,05) montrent que les performances entre les groupes sont équivalentes pour la tâche de reconnaissance à deux alternatives. A l’inverse, nous avons observé que les participants jeunes avaient significativement de meilleures performances que les âgés dans la tâche de reconnaissance à trois alternatives. Les profils mnésiques des participants seront étudiés à la lumière des modèles à deux processus de la reconnaissance. Nous faisons l’hypothèse d’un recours plus fréquent à la recollection chez les jeunes dans la tâche de reconnaissance à trois alternatives (vs deux alternatives), alors que le choix de l’item se ferait chez les âgés, en comparant directement les degrés de familiarité associés à chaque item et en sélectionnant le plus familier (Norman & O’Reilly, 2003). [less ▲]

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See detailDynamic interactions of a supercritical aerofoil in the presence of transonic shock buffet
Giannelis, N. F.; Vio, G. A.; Dimitriadis, Grigorios ULg

in Proceedings of the International Conference on Noise and Vibration Engineering, ISMA 2016 (2016, September 19)

Within a narrow transonic flight region, shock-wave/boundary-layer interactions yield large amplitude, self sustained shock oscillations that are detrimental to both platform handling quality and ... [more ▼]

Within a narrow transonic flight region, shock-wave/boundary-layer interactions yield large amplitude, self sustained shock oscillations that are detrimental to both platform handling quality and structural integrity. In this study, the aeroelastic interactions between this transonic buffet instability and a spring-suspended supercritical aerofoil are investigated by means of Reynolds-Averaged Navier-Stokes simulations. Single degree-of-freedom pitching simulations are performed for a range of structural to aerodynamic frequency ratios, sectional mass ratios and levels of structural damping. The results show that for a range of pitch eigenfrequencies above the fundamental buffet frequency, sychronisation of the aerodynamic and structural modes occurs. This so called lock-in phenomenon acts as a mechanism for large amplitude Limit Cycle Oscillation in aircraft structures within the transonic flow regime. The sectional mass and the addition of structural damping are both found to have a pronounced effect on the nature of the limit cycles [less ▲]

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See detailStretching the ecosystem service concept for application in real world situations
Boeraeve, Fanny ULg; Jacobs, Sander; Dendoncker, Nicolas et al

Conference (2016, September 19)

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See detailNonlinear identification and control of Organic Rankine Cycle systems using sparse polynomial models
Hernandez, Andres; Ruiz, Fredy; Ionescu, Clara et al

in Proceedings of the 2016 IEEE Conference on Control Applications (CCA) Part of 2016 IEEE Multi-Conference on Systems and Contro (2016, September 19)

Development of a first principles model of a system is not only a time- and cost- consuming task, but often leads to model structures which are not directly usable to design a controller using current ... [more ▼]

Development of a first principles model of a system is not only a time- and cost- consuming task, but often leads to model structures which are not directly usable to design a controller using current available methodologies. In this paper we use a sparse identification procedure to obtain a nonlinear polynomial model. Since this is a NP-hard problem, a relaxed algorithm is employed to accelerate its convergence speed. The obtained model is further used inside the nonlinear Extended Prediction Self-Adaptive control (NEPSAC) approach to Non- linear Model Predictive Control (NMPC), which replaces the complex nonlinear optimization problem by a simpler iterative quadratic programming procedure. An organic Rankine cycle system, characterized for presenting nonlinear time-varying dynamics, is used as benchmark to illustrate the effectiveness of the proposed combined strategies. [less ▲]

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See detailBeta cell regeneration from pancreatic ducts in adult zebrafish
Manfroid, Isabelle ULg

Poster (2016, September 18)

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See detailWhat is Beauty ?
XHAUFLAIRE, Gaël ULg

Conference (2016, September 17)

Aesthetic medicine and surgery are aimed to improve Beauty. But what is Beauty ? Could it be defined ? Measured ? Or is it a forever mysterious concept ? Is Beauty perception fashionable ? Or is it ... [more ▼]

Aesthetic medicine and surgery are aimed to improve Beauty. But what is Beauty ? Could it be defined ? Measured ? Or is it a forever mysterious concept ? Is Beauty perception fashionable ? Or is it intrinsic, in the mind of the beholder ? Do races, cultures and age have a role in the perception of Beauty ? Concepts of symmetry, koinophily (averageness), classical canons, Phi… could be useful tools to better apprehend an aesthetic treatment. [less ▲]

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See detailLes technologies génétiques, entre éthique et politique
Caeymaex, Florence ULg

Conference (2016, September 17)

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See detailOn-farm Evolution of Genetic Diversity of Four Old Varieties of Phaseolus vulgaris L.
Caproni, Leonardo; Raggi, Lorenzo; Klaedtke, Stephanie ULg et al

Poster (2016, September 16)

On-farm evolution of crop genetic diversity has a key role in adaptation of agricultural systems to changes. The aim of this work was to understand how four different old common bean varieties, which ... [more ▼]

On-farm evolution of crop genetic diversity has a key role in adaptation of agricultural systems to changes. The aim of this work was to understand how four different old common bean varieties, which being made of different genotypes can be referred to as populations, evolved on-farm during three years of multiplication (from 2012 to 2014) in two different experimental sites (Brittany and Luxembourg) under organic farming conditions. The four populations (Flageolet Chevrier Vert, Rognon de Coq, Roi des Belges, Saint Esprit à Œil Rouge) were chosen among those grown by two small-scale organic seed farmers while the commercial variety (Calima) was included as control. In 2015 the initial and the evolved populations were grown in a common field and characterized with morpho-phenological traits. In the same year, young leaf tissues were collected from 94 samples per population (total of 470 samples) for DNA extraction and molecular characterization. Genotyping was carried out using 22 SSR loci and fluorescent PCR amplicons analysed on an ABI3130xl sequencer. Molecular data were then used for multivariate analysis, analysis of molecular variance and pair-wise Fst statistics calculation. Genotyping resulted in the production of about 20K data points. A total of 83 different alleles were identified in 16 polymorphic loci ranging from two (BMb293, BM156, BMd-44) to 18 (BMd-43). The first two axis of the Principal Coordinates analysis (PCoA) explained 76,13% of total diversity and clearly distinguished the five groups of populations. Analysis of Molecular Variance (AMOVA) showed that 76, 20 and 4% of total diversity is among populations, individuals and within individuals, respectively. Only for multiplications carried out in Luxemburg significant differentiation between the original populations and final populations were found in two old varieties (Flageolet Chevrier Vert and Rognon de Coq, Fst = 0.117 and 0.143, respectively, P≤0.001). The results showed that in Luxemburg farmer practices and pedo-climatic conditions significantly shaped the diversity of the two populations. This is confirmed by phenotypic observations, as these multiplications also significantly differed (p<0.05) for flowering date for all varieties except 'Roi des Belges'. [less ▲]

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See detailWhat’s the difference? Results of a functional study of Aterian and Mousterian tools from the site of Ifri n’Ammar (Morocco)
Tomasso, Sonja ULg; Rots, Veerle ULg

Conference (2016, September 16)

Until today, the definition of the North African Mousterian has been based on a systematic comparison with the European Mousterian. Particularly the “Aterian” and its tanged tools have been widely ... [more ▼]

Until today, the definition of the North African Mousterian has been based on a systematic comparison with the European Mousterian. Particularly the “Aterian” and its tanged tools have been widely discussed. Researchers considered the tanged Aterian tools as early indications of the existence of hafting techniques [1]. It is currently not entirely understood how the Aterian relates to the Mousterian in North Africa, whether tanged tools can indeed be linked with hafting, and whether non-tanged tools were also hafted, which could indicate that a variety in hafting techniques existed. The site of Ifri n’Ammar presents an ideal chance to compare Aterian and Mousterian technocomplexes. The rock shelter is located in the eastern Moroccan Rif and has a rich and well preserved stratigraphy where Middle Paleolithic tools are abundantly represented [2]. At Ifri n’Ammar, the Aterian and Mousterian assemblages are inter-stratified, which means that the relationship of these industries cannot simply be explained in terms of chronological succession [2,3]. The density of retouched artefacts differs between the Aterian and the Mousterian levels and tanged tools are present in the denser Aterian levels only. These levels also show a higher overall tool frequency. We present the results of a functional study focusing on the artefacts from the upper levels (“Occupation supérieure”) of Ifri n’Ammar, dated between 83 ± 6 ka and 130 ± 8 ka [3]. The functional study was combined with a specific experimental program designed to address questions raised during the analysis of the archaeological material, with a specific focus on hafting. Diagnostic microscopic wear patterns confirm that the tanged tools were used while hafted. Tanged tools did not prove to be related to hunting activities only, but various tool uses could be identified. They all fit, however, within the context of hunting and animal processing activities. The reuse of hafted armatures for other activities is not evident in the present sample. [less ▲]

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See detailWhat are the optimal walking tests to assess disability progression?
Pierard, Sébastien ULg; Van Droogenbroeck, Marc ULg

in Multiple Sclerosis Journal (2016, September 16), 22(S3), 452-453

Background. Therapy success is assumed when there is no evidence of disease activity. Clues to show it include an MRI, the relapses history, questionnaires, and clinical measures to assess the disability ... [more ▼]

Background. Therapy success is assumed when there is no evidence of disease activity. Clues to show it include an MRI, the relapses history, questionnaires, and clinical measures to assess the disability progression. Especially gait analysis plays a major role as gait impairment is considered by patients as the most disabling symptom. Too often only the walking speed is measured. New technologies (eg GAIMS, see ECTRIMS 2012-15) measure many spatiotemporal gait parameters, even during long tests (\eg 6min, 500m), without equipping patients with markers or sensors. Moreover, various tests can be done, depending on the length and type of walk (comfortable pace --C--, as fast as possible --F--, tandem gait --T--). Objective. Determine if there is an advantage to perform various walking tests, and which test or combination of tests brings the higher amount of information about the patient state in a reasonable amount of acquisition time. Methods. The system GAIMS provided 434 recordings of the gait parameters of healthy people and 60 recordings of MS patients with EDSS<= 4. They performed 12 tests (25ft C+F+T each twice, 20m C+F+T, 100m C+F, 500m F). To assess the ability of these clinical outcome measures to detect disability progression, we evaluate the possibility of differentiating the persons below a given EDSS threshold (0.25) from those above it based only on the measured gait parameters. For individual tests, we use the classifier of Azrour (ESANN 2014). All subsets of the tests are also considered, by combining the individual classifiers and determining automatically the optimal relative importance of the tests with the linear support vector machine (SVM) technique. The ability to detect the disability progression is quantified by the performance (area under the ROC curve --AUC-- and the maximum achievable balanced accuracy --MBA--) of the corresponding classifiers. Results. The best test alone is the 500m F (note that the walking speed measured during it is the gait parameter best correlated with the EDSS). Combining several tests leads to a better performance. A performance (MBA=95.7%, AUC=0.983) close to the best achievable one can be obtained with 6 tests only (25ft C twice, 25tf F twice, 20m C, 20m T). Conclusions. The clinical gait analysis can help to detect disability progression. While considering different types of walking tests improves the ability of taking decisions, we showed that performing 6 tests for a total of 70.48m suffices. [less ▲]

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See detailObjective drowsiness monitoring to assess fitness for duty
François, Clémentine ULg; Hoyoux, Thomas ULg; Langohr, Thomas ULg et al

Poster (2016, September 16)

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See detailMetabolites from media supplemented with 3’-sialyllactose and fermented by bifidobacteria have an antivirulent effect against intestinal pathogens
Bondue, Pauline ULg

Poster (2016, September 16)

Introduction Complex oligosaccharides from human milk (HMO) promote growth of bifidobacteria such as Bifidobacterium bifidum [1]. Whey, a by-product of dairy-industry, contents complex oligosaccharides ... [more ▼]

Introduction Complex oligosaccharides from human milk (HMO) promote growth of bifidobacteria such as Bifidobacterium bifidum [1]. Whey, a by-product of dairy-industry, contents complex oligosaccharides (BMO) similar to HMO, which are mainly represented in colostrum by 3’-sialyllactose (3’SL) [2]. Bifidobacterium crudilactis, a species of bovine origin, encodes for β galactosidases and α-glucosidases and could therefore be able to metabolise those BMO [3; 4; 5]. In addition, fermentation products from bifidobacteria can produce antivirulent activity against intestinal pathogenic bacteria [6; 7]. This study focused on capacity of bifidobacteria to metabolise BMO, more particularly 3’SL, and on potential antivirulent effect of cell-free spent media (CFSM) against virulence gene expression of pathogenic bacteria. Material and methods B. bifidum BBA1 and B. crudilactis FR/62/B/3 isolated respectively from breastfed children feces and from cow raw milk cheese were grown on media supplemented with BMO or 3’SL, as sole source of carbon. The CFSM were harvested after centrifugation of cells culture, freeze-dried and concentrated 10 fold. Next, their effects were tested against virulence gene expression using ler and hilA promoter activity of luminescent constructs of Escherichia coli 0157:H7 ATCC 43888 and Salmonella Typhimurium SA 941256, respectively. The effect was confirmed on wild type strains of E. coli O157:H7 ATCC 43890 and S. Typhimurium ATCC 14028 using RT-qPCR. Results Both strains were able to grow in presence of whey or 3’SL, but B. crudilactis showed the best growth compared to B. bifidum. The highest cell concentrations were observed with media containing whey (8.9 ± 0.6 log cfu/ml and 8.1 ± 0.3 log cfu/ml, respectively). CFSM from fermented media supplemented with 3’SL resulted in under-expression of hilA and ler genes for the luminescent constructs and in under-expression of ler (ratios of -15.4 and -8.1) and qseA (ratios of -2.1 and -3.1) genes for the wild type strain of E. coli O157:H7. No effect was observed for the wild type strain of S. Typhimurium. Discussion B. crudilactis presented the best growth potential probably because its genome encodes the enzymatic machinery to use BMO (β galactosidases and α-glucosidases) [3; 4; 5]. The positive effect of media supplemented with milk products on growth of probiotics has been demonstrated previously [8]. CFSM obtained from media supplemented with 3’SL down-regulate several virulence genes of E. coli O157:H7 and potentially S. Typhimurium. This effect has been observed previously with CFSM obtained from fermentation of lactic acid bacteria or bifidobacteria, by production of antivirulent metabolites [2; 3]. BMO combined with some bifidobacteria strains of bovine or human origin could therefore be an interesting synbiotic to maintain or restore the intestinal health of young children. These effects observed in vitro will be further investigated regarding the exact nature of the active molecules. References 1. Garrido D. et al. (2013). Microbiology 159: 649-664. 2. Urashima T. et al. (2013). Biosci Biotechnol Biochem 77: 455-466. 3. Sela D. A. (2011). Int J Food Microbiol 149: 58-64. 4. Milani C. et al. (2014). Appl Environ Microbiol 80: 6290-6302. 5. Bondue P. & Delcenserie V. (2015). Korean J Food Sci Anim Resour 35: 1-9. 6. Medellin-Pena M. J. et al. (2007). Appl Environ Microbiol 73: 4259-4267. 7. Bayoumi M. A. & Griffiths M. W. (2012). Int J Food Microbiol 156: 255-263. 8. Champagne C. P. et al. (2014). Can J Microbiol 60: 287-295. [less ▲]

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See detailIntroduction
Masson, Christophe ULg

Conference (2016, September 15)

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See detailDevelopment of a semiochemical-based control method against the walnut husk fly, Rhagoletis completa Cresson
Sarles, Landry ULg; Lognay, Georges ULg; Verhaeghe, Agnès et al

Poster (2016, September 15)

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See detailCHARACTERISATION OF THE STRUCTURAL, DYNAMIC AND AGGREGATION PROPERTIES OF THE W64R AMYLOIDOGENIC MUTANT OF LYSOZYME
Vettore, Nicola; Kumita, Janet; Moray, Joël ULg et al

Poster (2016, September 15)

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See detailLa Paix de Fexhe : un texte, des acteurs
Masson, Christophe ULg

Conference (2016, September 15)

La Paix de Fexhe fut le résultat d’un compromis entre les cinq différents « partis » politiques liégeois de l’époque : le prince-évêque, le chapitre cathédral de Saint-Lambert, le « patriciat » urbain, la ... [more ▼]

La Paix de Fexhe fut le résultat d’un compromis entre les cinq différents « partis » politiques liégeois de l’époque : le prince-évêque, le chapitre cathédral de Saint-Lambert, le « patriciat » urbain, la noblesse et les artisans. Nous étudierons donc dans le cadre de cette contribution l’identité de ces partis, ainsi que celles des délégués qu’ils envoyèrent à Fexhe, leur « agenda politique » et leurs moyens d’action. Nous reviendrons ensuite sur la part que chacun prit à la rédaction du texte du 18 juin 1316 et de ses deux compléments ratifiés le même jour et le lendemain, ce qui nous permettra de mesurer la place que chacun put faire tenir à ses revendications, nuançant, pour le moins, la lecture « démocratique » ou « ecclésio-paternaliste » en cours depuis le xixe siècle. De façon complémentaire, nous mettrons en évidence les champs d’application et les limites de ces textes, en les articulant avec ceux qui les précédèrent afin de mieux en percevoir les implications sur la longue durée de l’histoire liégeoise. [less ▲]

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See detailFirst come first served: “priority effect“ benefits Ambrosia artemisiifolia L. more than other ruderal Asteraceae species
Ortmans, William ULg; Mahy, Grégory ULg; Monty, Arnaud ULg

Poster (2016, September 14)

Ambrosia artemisiifolia L. (common ragweed, Asteraceae) is an invasive weed causing a health crisis in Europe, due to its highly allergenic pollen. In Western Europe the invaded range covers most of ... [more ▼]

Ambrosia artemisiifolia L. (common ragweed, Asteraceae) is an invasive weed causing a health crisis in Europe, due to its highly allergenic pollen. In Western Europe the invaded range covers most of central and southern France, and northern Italy. Northwards beyond the edge of this range, occurrence of casual population have been described for years, but these populations do not appear to become invasive, and the species does not seem to spread. This situation raises the following question: Has the invaded range reached a limit or will the species continue its invasion northwards? To answer this question, we followed two complementary approaches. First we set up an experimental garden in Belgium, 250 km north to the current invaded range, to see if the local climate allows the completion of the species reproduction cycle. Second, we performed an in situ measurement campaign in 12 population located beyond the edge, within the range but near the margin, and in the center of the invaded range. The aim of this campaign was to test whether the species had reduced plant performance towards range margins. The results showed that the species is able to establish populations with high growth rates in Belgium. Furthermore, the species expressed similar performance across the considered areas, even beyond the current invasion front. No evidence of processes constraining the invasion was found, which suggests a great potential for invasion north to the current invaded range. In this uncertain situation, awareness actions should be considered in the northern countries. [less ▲]

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See detailAssessment of vertical contamination of Cd, Pb and Zn in soils around a former ore smelter in Wallonia, Belgium
Liénard, Amandine ULg; Colinet, Gilles ULg

Conference (2016, September 14)

Examples of sites contaminated by atmospheric fallouts are numerous across former industrial areas, among which the valleys of Sambre and Meuse in Wallonia hosted metal ore treatment factories. We have ... [more ▼]

Examples of sites contaminated by atmospheric fallouts are numerous across former industrial areas, among which the valleys of Sambre and Meuse in Wallonia hosted metal ore treatment factories. We have studied the fate of Cd, Pb and Zn in soils affected by atmospheric deposition in the vicinity of old smelters. The importance of vertical redistribution of contaminants in soils is questioned and the aims of this paper are to i) characterize the vertical distribution of TEs and soil properties along diverse soil profiles, ii) evaluate enrichment or impoverishment of TEs along the profiles to discriminate anthropogenic or geogenic origin of contaminations and iii) evaluate whether soil type or land use influenced the mobility of contaminants in the selected profiles. Concentrations of trace elements (Cd, Co, Cr, Cu, Ni, Pb, and Zn) and major elements (Ca, Mg, K, Fe, Al, and Mn) as well as pHKCl and TOC were measured on 22 profiles located in a 3 km radius of a former ore treatment plant in Wallonia (Belgium). Enrichment factor (EF), vertical impoverishment factor (VIF), and availability ratio (AR) were used as diagnostic tools of contamination and migration of Cd, Pb, and Zn in profiles. Data revealed that soil profiles are significantly contaminated. The ranges of enrichment factors for Cd (17-3570), Pb (1-2883), and Zn (2-309) are very broad with the higher EF in the topsoil of profile. VIFs of subhorizons are rarely above 1. In a few remaining cases with VIF > 1, the main factor explaining is soil type (especially, Colluvic Regosols, Luvisols, and, Cambisols with shale load). Cd, Pb and Zn ARs are strongly correlated with TOC and to a lesser extent with pHKCl. Pb and Zn ARs are influenced by soil type and land use only plays on Zn AR. The Cd availability is independent by these two factors. The contents of trace elements measured in soil profiles are very high especially in topsoil. Until now, the Cd, Pb, and Zn vertical distribution shows a low migration from topsoil up to depth. However, we must not minimize the hazard of a future potential transfer. [less ▲]

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See detailExtremophile plants as source of biopesticides against European damageable plant pathogens
Ben Kaab, Sofiène ULg; Parisi, Olivier ULg; De Clerck, Caroline ULg et al

Poster (2016, September 14)

The use of plant-derived products in postharvest disease management may be a valid alternative to conventional chemical treatments (Pane et al., 2016). Unfavorable environmental conditions (such as salt ... [more ▼]

The use of plant-derived products in postharvest disease management may be a valid alternative to conventional chemical treatments (Pane et al., 2016). Unfavorable environmental conditions (such as salt and drought) increase production and accumulation of reactive oxygen species (ROS). Consequently, extremophile plants have developed adaptive responses including the synthesis of specific bioactive molecules used for medical and nutritional purposes (Ksouri et al., 2012). In that context, the main objective of the present study was the identification of effective plant extracts and essential oils from extremophile plants against the most important plant pathogens in Europe (in term of loss, treatment necessity and/or cost). The study began with the selection of four endemic medicinal species suspected to be antimicrobial due to their wealth of phenolic and terpene compounds, such as flavonoids, phenolic acids, and coumarins (Ksouri et al., 2012). Each of the aerial plant materials was grounded and macerated with solvent (methanol or chloroform) for 24 h. The solvent was then eliminated along rotavapor. The yield of plant extract varied between 1.56 and 6.7%. Kinetics of growth of the 3 pathogens cultivable in liquid medium was determined before testing the impact of plant extracts and essential oils. Methanolic and chloroform plant extracts (EM1, EM2, EC1 and EC2) and essential oils (EO1, EO2) were compared for their antifungal potential. The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts was analyzed by GC/MS. Yield of essential oil varied between 0.7 and 1.2%. Therefore, antifungal activity of plant extracts and essential oils was evaluated using ELISA microplates with a blocked randomized design, as described previously (Parisi et al., 2013). The results obtained showed that EM2 at 7 mg/ml has a very high fungistatic activity against Fusarium culmorum, F. oxysporum and Penicillium italicum. It was characterized with a high amount of polyphenols, flavonoids and condensed tannins. Statistical analysis showed that the efficiency of methanol extracts significantly differed from those of the chloroform extracts. In addition, essential oils significantly reduced spores germination in a dose-dependent manner. Their fungistatic activity reached 100% at 6000 ppm. In conclusion, this work allowed us to open new perspectives on the application of extremophile plant extracts as novel biocontrol strategy against plant pathogens. [less ▲]

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See detailTHERMO-ECONOMIC OPTIMIZATION OF ORGANIC RANKINE CYCLE SYSTEMS FOR WASTE HEAT RECOVERY FROM EXHAUST AND RECIRCULATED GASES OF HEAVY DUTY TRUCKS
Guillaume, Ludovic ULg; Legros, Arnaud; Lemort, Vincent ULg

Conference (2016, September 14)

Waste heat recovery (WHR) ORC is a very promising technology for reducing fuel consumption and consequently the CO2 emissions of future heavy-duty trucks (HDT). Nonetheless, the adoption of this ... [more ▼]

Waste heat recovery (WHR) ORC is a very promising technology for reducing fuel consumption and consequently the CO2 emissions of future heavy-duty trucks (HDT). Nonetheless, the adoption of this technology in the automotive domain requires specific R&D activities going from the system definition to the on-board integration. This study focuses on the preliminary design phase of ORC systems recovering the heat wasted from two of the sources available on a HDT: the exhaust and recirculated gases. From these heat sources and their combinations, 6 possible architectures are identified. On the other hand, 4 volumetric expansion machine technologies are considered (Scroll, Screw, Piston and Vane Expanders). At the end, 24 topologies are modelled considering only the main components (Pump, Heat exchangers, Expansion machines). A three-step optimization method is proposed to identify the most promising system. First, the most suitable design conditions are identified using a simple model of expansion machine. In a second step, the design phase, using more detailed models for the expansion machines, a thermodynamic and economic optimizations are performed. Finally, in a third step, the output power of the latter system models is maximized in off-design conditions. [less ▲]

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See detailDYNAMIC MODELING OF WASTE HEAT RECOVERY ORGANIC RANKINE CYCLE SYSTEMS IN THE AMESIM PLATFROM
Guillaume, Ludovic ULg; Ameel, Bernd; Criens, Chris et al

Conference (2016, September 14)

ORC waste heat recovery is a very promising technology for reducing fuel consumption and consequently the CO2 emissions of future heavy-duty trucks. Because of the transient nature of the heat sources ... [more ▼]

ORC waste heat recovery is a very promising technology for reducing fuel consumption and consequently the CO2 emissions of future heavy-duty trucks. Because of the transient nature of the heat sources encountered on a truck, dynamic simulations are an essential part of the design process of ORC systems for truck applications. Dynamic models are useful for component design, control design and transient evaluation of ORC systems. To ease the burden of building numerous dynamic models of different candidate ORCs while the design process is ongoing, a library of generic dynamic models of ORCs is built in this work. These models work in synergy with a steady-state ORC design tool in which is added a function to automatically populate the parameters of the dynamic models. In this work, the dynamic model library and their parameterization process in LMS AMESim are described. The platform is largely used in automotive industry and offers a variety of libraries: Engine, Control, Two-Phase Flow, etc. Finally, the dynamic models are compared against the steady-state models and experimental data. [less ▲]

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See detailSemi-continuous fermentation of a thermotolerant and high acetic acid producing Acetobacter pasteurianus bacterium
Mounir, Majid ULg; Thonart, Philippe; Ismaili Alaoui, Mustapha et al

Conference (2016, September 14)

Among 63 strains isolated from fruits and homemade vinegars from different ecosystems of Morocco, a thermotolerant bacterium with high production of acetic acid was selected and evaluated for its ability ... [more ▼]

Among 63 strains isolated from fruits and homemade vinegars from different ecosystems of Morocco, a thermotolerant bacterium with high production of acetic acid was selected and evaluated for its ability to perform efficient acetous fermentation at high temperature in a bioreactor. CV01 strain, isolated from cactus (Opuntia ficus-indica), was considered to be an Acetobacter pasteurianus sp. according to phylogenetic study based on 16s rDNA gene sequence analysis. An optimal culture medium containing initial concentrations of acetic acid and ethanol of 1% (v/v) and 4% (v/v), respectively, was used. The growth kinetics of this isolate were monitored in flasks and compared with those of the wild type LMG 1625 mesophilic strain and the thermoresistant Acetobacter senegalensis reference strain. The CV01 strain exhibited abundant growth along with high amount of produced acetic acid at high temperature (41°C). Subsequently, a 20-L stirred tank bioreactor was used to assess thermotolerance and acidoresistance properties of the selected strain during semi-continuous acetic acid fermentation at 38°C. Interestingly, a total amount of 13.4% (w/v) acetic acid was yielded at the end of fermentation. Moreover, this bacterium could produce during the same fermentation process a final concentration of 11.2 g/L gluconic acid, a sensory quality indicator in vinegar production. Finally, the enzymatic study showed that CV01 strain exhibited high ADH and ALDH enzyme activity at 38°C compared with the mesophilic reference strain LMG 1632, which was significantly susceptible to thermal inactivation. [less ▲]

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See detailEffects of seed traits variation on seedling performance of the invasive weed, Ambrosia artemisiifolia
Monty, Arnaud ULg; Mahy, Grégory ULg; Ortmans, William ULg

Poster (2016, September 14)

Seedling performance can determine the survival of a juvenile plant and impact adult plant performance. Understanding the factors that may impact seedling performance is thus critical, especially for ... [more ▼]

Seedling performance can determine the survival of a juvenile plant and impact adult plant performance. Understanding the factors that may impact seedling performance is thus critical, especially for annuals, opportunists or invasive plant species. Seedling performance can vary among mothers or populations in response to environmental conditions or under the influence of seed traits. However, very few studies have investigated seed traits variations and their consequences on seedling performance. Specifically, the following questions have been addressed by this work: 1) How the seed traits of the invasive Ambrosia artemisiifolia L. vary among mothers and populations, as well as along the latitude; 2) How do seed traits influence seedling performance; 3) Is the influence on seedlings temperature dependent. With seeds from nine Western Europe ruderal populations, seed traits that can influence seedling development were measured. The seeds were sown into growth chambers with warmer or colder temperature treatments. During seedling growth, performance-related traits were measured. A high variability in seed traits was highlighted. Variation was determined by the mother identity and population, but not latitude. Together, the temperature, population and the identity of the mother had an effect on seedling performance. Seed traits had a relative impact on seedling performance, but this did not appear to be temperature dependent. Seedling performance exhibited a strong plastic response to the temperature, was shaped by the identity of the mother and the population, and was influenced by a number of seed traits. [less ▲]

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See detailDéveloppement territorial, foncier économique et infrastructures
Halleux, Jean-Marie ULg

Conference (2016, September 13)

Detailed reference viewed: 21 (0 ULg)
See detailInvestigating the effect of plant-derived amendments on PAHs degradation in brownfield contaminated soils
Davin, Marie ULg; Starren, Amandine ULg; Colinet, Gilles ULg et al

Conference (2016, September 13)

Polycyclic aromatic hydrocarbons (PAHs) are a class of persistant organic compounds of major concern that tend to accumulate in the environment, damaging ecosystems and health. Brownfields represent an ... [more ▼]

Polycyclic aromatic hydrocarbons (PAHs) are a class of persistant organic compounds of major concern that tend to accumulate in the environment, damaging ecosystems and health. Brownfields represent an important tank for PAHs that require remediation. As an alternative to environmentally aggressive, expensive and often disruptive soil remediation strategies, experiences have been carried on to understand and develop techniques based on bioremediation and phytoremediation. PAHs degradation experiments were conducted in microcosms (laboratory scale) in order to determine whether several plant-derived amendments could enhance bioremediation. Briefly, samples of aged contaminated soils were treated with different concentrations of Medicago sativa or Trifolium pratense root exudates or dried roots, commercial saponin, a natural surfactant found in some plant roots such as some Fabaceae, and some samples were left unamended as controls. Soil samples were incubated for two and four weeks at controlled temperature (28°C). Carbon dioxide emission was monitored throughout the whole incubation. At the end of each experiment, dehydrogenase activity was measured as an indicator of microbiological activity and residual PAHs were determined using High-Performance Liquid Chromatography with Fluorimetric Detection (HPLC-FLD). In total, eleven amendment modalities and two incubation periods were tested and repeated four times. Preliminary experiments show promising results as amended samples seem to show different respiration activities. Ongoing studies will allow discussion as to whether or not PAHs degradation is influenced by the different modalities and if there are any differences according to the nature and concentration of the amendment. [less ▲]

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See detailIs Ambrosia artemisiifolia L. able to expand its invaded range northward in Western Europe?
Ortmans, William ULg; Mahy, Grégory ULg; Monty, Arnaud ULg

Conference (2016, September 13)

Ambrosia artemisiifolia L. (common ragweed, Asteraceae) is an invasive weed causing a health crisis in Europe, due to its highly allergenic pollen. In Western Europe the invaded range covers most of ... [more ▼]

Ambrosia artemisiifolia L. (common ragweed, Asteraceae) is an invasive weed causing a health crisis in Europe, due to its highly allergenic pollen. In Western Europe the invaded range covers most of central and southern France, and northern Italy. Northwards beyond the edge of this range, occurrence of casual population have been described for years, but these populations do not appear to become invasive, and the species does not seem to spread. This situation raises the following question: Has the invaded range reached a limit or will the species continue its invasion northwards? To answer this question, we followed two complementary approaches. First we set up an experimental garden in Belgium, 250 km north to the current invaded range, to see if the local climate allows the completion of the species reproduction cycle. Second, we performed an in situ measurement campaign in 12 population located beyond the edge, within the range but near the margin, and in the center of the invaded range. The aim of this campaign was to test whether the species had reduced plant performance towards range margins. The results showed that the species is able to establish populations with high growth rates in Belgium. Furthermore, the species expressed similar performance across the considered areas, even beyond the current invasion front. No evidence of processes constraining the invasion was found, which suggests a great potential for invasion north to the current invaded range. In this uncertain situation, awareness actions should be considered in the northern countries. [less ▲]

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See detailMethodik zur schnellen Bewertung von Syntheserouten auf Basis von Exergiebilanzen
Frenzel, Philipp; Pfennig, Andreas ULg

Conference (2016, September 13)

Heutige chemische Produkte basieren fast ausschließlich auf erdölbasierten Rohstoffen. Aufgrund weltweiter Bemühungen, die Abhängigkeit von fossilen Rohstoffen zu reduzieren, wird in den letzten Jahren ... [more ▼]

Heutige chemische Produkte basieren fast ausschließlich auf erdölbasierten Rohstoffen. Aufgrund weltweiter Bemühungen, die Abhängigkeit von fossilen Rohstoffen zu reduzieren, wird in den letzten Jahren verstärkt die Nutzung alternativer Kohlenstoffquellen wie Biomasse oder CO2 erforscht. Die alternativen Kohlenstoffquellen unterscheiden sich hinsichtlich ihrer Zusammensetzung und Stoffeigenschaften teilweise deutlich von fossilen Rohstoffen. Aus diesem Grund müssen Syntheserouten und darauf aufbauende Prozesse neu entwickelt werden. Da zum einen sehr viele Syntheserouten prinzipiell denkbar sind und zum anderen die Entwicklung der entsprechenden Prozesse aufwendig ist, wird eine Möglichkeit benötigt, begrenzte Entwicklungsressourcen sinnvoll zu steuern. Dazu sollte bereits in einem frühen Entwicklungsstadium ein quantitativer Vergleich der Syntheserouten erfolgen, um diejenigen zu identifizieren, die das größte wirtschaftliche Potential versprechen. In diesem Vortrag wird eine Methodik vorgestellt, um eine schnelle erste, auf Exergie basierte Bewertung des wirtschaftlichen Potentials einer Syntheseroute bereits in einem frühen Entwicklungsstadium durchzuführen, in dem nur wenige Informationen vorliegen. Die Idee der Methodik ist, Syntheserouten in standardisierten Prozessen abzubilden, wodurch eine automatisierte Auswertung und somit ein schnelles Screening möglich wird. Die standardisierten Prozesse umfassen sowohl den Einfluss der Reaktion durch Abbildung der Reaktionsbedingungen, Stöchiometrie, Umsatz und Selektivität als auch die Auswirkungen der Trennaufgabe. Ebenso berücksichtigt wird die Rückführung von Lösungsmitteln und ggf. nicht umgesetzten Edukten. Als zentrale Bewertungsgröße zur Abschätzung des wirtschaftlichen Potentials wird eine Kombination aus Exergie- und Rohstoffeinsatz herangezogen. Der Vorteil von Exergiebilanzen gegenüber Energiebilanzen ist, dass die Produktion von Entropie berücksichtigt wird und so die Auswirkungen einzelner Prozessschritte untersucht und zwischen verschiedenen Energieformen unterschieden werden kann. Durch Berechnung der Exergieverluste, also der Verluste von Exergie aufgrund von Entropieerzeugung in den Prozessen, ergibt sich ein quantitativer Vergleich verschiedener Syntheserouten. [less ▲]

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See detailModelling the mortality of Hylotrupes bajulus (L.) larvae exposed to anoxic treatment for disinfestation of wooden art objects
de Streel, Géraud; Henin, Jean-Marc; Bogaert, Patrick et al

Conference (2016, September 13)

Experiments were conducted to quantify the effect of several variables on the mortality of insects exposed to an anoxic treatment in order to generate a model linking mortality to these variables. This ... [more ▼]

Experiments were conducted to quantify the effect of several variables on the mortality of insects exposed to an anoxic treatment in order to generate a model linking mortality to these variables. This study aims to explore the possible interest of using such a model to determine the characteristics of treatment (especially duration) needed to guarantee insect mortality with a given level of probability. Trials were performed on Hylotrupes bajulus larvae, which is a widespread species known for its high tolerance to anoxic conditions. The studied variables are the initial mass of the larvae, the treatment temperature (21, 30 and 40 °C), the treatment duration (four durations for each temperature tested) and whether the larva is held in wood or in a petri dish (directly exposed to anoxic atmosphere) during the experiment. It was found that, while the last variable is not correlated with mortality, treatment duration and temperature are significantly and positively correlated with it. Larvae with higher body mass were also shown to have a better resistance to the treatment. Based on these results, a model including insect initial mass, treatment temperature and duration, together with the interaction between these two variables, was determined. This relatively simple model appeared to be a useful tool in overcoming the difficulty in defining the modalities for anoxic treatment in order to reach a given level of mortality. [less ▲]

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See detailOrganocatalytic ring-opening polymerization towards polyphosphoesters
Clément, Benoit; Vanslambrouck, Stépanie; Carion, Stéphan ULg et al

Conference (2016, September 13)

Hydrolytically degradable and biocompatible aliphatic polyesters are widely applied for biomedical applications as implants, scaffolds for tissue engineering and, finally, as nanocarriers for drug ... [more ▼]

Hydrolytically degradable and biocompatible aliphatic polyesters are widely applied for biomedical applications as implants, scaffolds for tissue engineering and, finally, as nanocarriers for drug delivery. Aliphatic phophoesters, known since the pioneering work of S. Penczek in the 70’s, exhibit the same properties of hydrolytic degradability and biocompatibility and are thus more and more studied for biomedical applications as well. In the field of materials, anti-fire properties opens up new perspectives. The difference between polyesters and polyphosphoesters in terms of synthesis and properties will be highlighted. Polyphosphosphoesters are synthesized by step-growth and chain growth polymerization. When these polyphosphoesters are synthesized by ring-opening polymerization of cyclic phosphoesters, organocatalysts turned out to be very efficient compared to coodination processes. The last part of the talk will deal with te implementation of ROP of cyclic phosphates towards a series of amphiphilic PEO-block-polyphosphate copolymers of tailored hydrophobicity depending on the length of the lateral alkyl group. These polymers are able to self assemble into nanoparticles by direct dissolution in water, thus in the absernce of any organic solvent. The so-obtained micelles were studied by a set of techniques (Pyrene Fluorescence, Dynamic Light Scattering, Tensiometry). Finally, the influence of the hydrophobicity of the polyphosphate block of the micelle on the encapsulation and the release of a model drug was investigated. [less ▲]

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See detailMicrostructural design using stress–based topology optimization
Collet, Maxime ULg; Bruggi, Matteo; Noël, Lise ULg et al

Conference (2016, September 12)

New additive manufacturing techniques break the limitations encountered for years when producing components descending from topology optimization. Classical design procedures focus on macro-structural ... [more ▼]

New additive manufacturing techniques break the limitations encountered for years when producing components descending from topology optimization. Classical design procedures focus on macro-structural optimization to sustain given loads but today innovative manufacturing processes allow considering structures exhibiting tailored microstructures, i.e. the well known microstructural design. The practical applications of structures including material design is mainly motivated by the greater performances that can be achieved compared to classical solutions. Microstructural design has been shown a great interest as attested by recent works. However, stress–based topology optimization has not yet been extensively exploited when addressing microstructural design using numerical homogenization though stress constraints is an important feature and have gained in interest in the field of topology optimization. This contribution investigates the problem of material design enforcing stress constraints within periodic microstructures by considering a representative volume element (RVE) subject to prescribed strain fields. The SIMP approach is adopted as material interpolation law while the optimization problems are solved using a sequential convex programming approach. In particular the well known method of moving asymptotes (MMA) is considered. Numerical homogenization is used to assess the effective elastic properties of the microstructures. The Von Mises stress criterion is used to impose the constraints on the stress level. This work discusses the formulation of a well-posed design problem as well as some numerical issues encountered. The developed solution procedure is first validated by comparison against analytical results, e.g. the single inclusion of Vigdergauz microstructure. [less ▲]

Detailed reference viewed: 131 (7 ULg)