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See detailMeasuring the body, measuring through the body
Vangeebergen, Thomas ULg

Conference (2014, June 13)

Body is a particular relevant way to tackle design processes, because of the multiplicity of status it can acquire during these processes: a source of information, a target to fit, a device to perform, a ... [more ▼]

Body is a particular relevant way to tackle design processes, because of the multiplicity of status it can acquire during these processes: a source of information, a target to fit, a device to perform, a complex technology, an apparatus for the users. A specific body is presented in this paper: the measured body. Trough racial anthropology, sport performances, demographic statistics, medical treatments, psycho-cognitive surveys, quantified self, or in many other contexts, human body is subject to a wide range of various measures. I would on my own propose some thoughts grounded on field exploration, concerning sensory analysis practices, in various laboratories. According to the symmetrical glaze STS have gave from the beginning to both human and non-humans, objects and subjects, the body is for a start itself one of the “stuffs” overlapping categories, blurring distinctions between things and persons, at the same a time a given and an object to perform. The measures of the body, and made with/through the body, highlight how it could be enacted, revealed, understood, improved by technology, especially when it requires some quantitative data. But it allows us also to grasp how the body is viewed simultaneously as a technological device and as the data origin, to intervene during complex practices (e.g. standardization, lab experiments, and marketing surveys). One of the numerous outcomes of such research could be the role of these bodily measurements in the definition of the actors, as well individuals than collectives. By the way it takes on a share on the network tying body to numerical data and to materiality-other-than-human, to measure the body/ through the body seems to afford socio-materiality in a particularly productive manner. Many scholars have inquired about numbers, how they could bring objectivity, how they produce confidence and security, and how finally they participate to black-box the measures themselves. Here, the aim is to understand the specificity of the body as measurement issue, being the interface of the-objects-to-be-measured and the instrument-of-measure. [less ▲]

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See detailCopper recovery from waste electric cables by biohydrometallurgy
Lambert, Fanny ULg; Bastin, David ULg

Conference (2014, June 13)

This study examines the leaching of copper from waste electric cables by chemical leaching and leaching catalysed by Acidithiobacillus ferrooxidans in terms of leaching kinetics and reagents consumption ... [more ▼]

This study examines the leaching of copper from waste electric cables by chemical leaching and leaching catalysed by Acidithiobacillus ferrooxidans in terms of leaching kinetics and reagents consumption. Operational parameters such as the nature of the oxidant (Fe3+, O2), the initial ferric iron concentration (0-10 g/L) and the temperature (21-50°C) were identified to have an important influence on the degree of copper solubilisation. At optimal process conditions, copper extraction above 90% was achieved in both leaching systems, with a leaching duration of 1 day. The bacterial leaching system slightly outperformed the chemical one but the positive effect of regeneration of Fe3+ was limited. It appears that the Fe2+ bio-oxidation is not sufficiently optimised. Best results in terms of copper solubilisation kinetics were obtained for the abiotic test at 50°C and for the biotic test at 35°C. Moreover, the study showed that in same operating conditions, a lower acid consumption was recorded for the biotic test than for the abiotic test. [less ▲]

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See detailTrouble de la reconnaissance de soi chez des personnes atteintes de la maladie d'Alzheimer
Moyse, Evelyne ULg; Bastin, Christine ULg; Salmon, Eric ULg et al

Poster (2014, June 12)

Introduction : Outre des difficultés de mémoire épisodique, la maladie d’Alzheimer est associée à une altération progressive du fonctionnement de la mémoire sémantique où les connaissances du passé ... [more ▼]

Introduction : Outre des difficultés de mémoire épisodique, la maladie d’Alzheimer est associée à une altération progressive du fonctionnement de la mémoire sémantique où les connaissances du passé lointain sont mieux préservées que les connaissances acquises récemment. De plus, il a été rapporté que ce type de perte peut aussi se produire pour la reconnaissance de son propre visage. Une étude décrivait le cas d’une femme atteinte de la maladie d’Alzheimer à un stade avancé qui était incapable de se reconnaître sur des photographies prises dans un passé récent mais qui avait peu voire pas de difficultés à se reconnaître sur des photographies prises pendant les deux premières décennies de sa vie adulte. Cependant, la description d’une seule étude de cas pourrait être vue comme anecdotique. Objectifs : L’objectif de cette étude est d’évaluer si ce type de difficultés peut s’observer dans un plus large échantillon de patients. Pour ce faire, des patients à des stades légers à modérés de la maladie sont comparés à des sujets âgés sains sur une tâche de reconnaissance de visages (soi, familier, inconnu) appartenant à différentes périodes de vie (20 ans jusqu’à récemment). Résultats : Au stade léger, les patients présentaient des difficultés uniquement pour reconnaître le visage d’une personne familière alors qu’au stade modéré de la maladie, ces difficultés s’observaient à la fois pour le visage familier et le propre visage. De plus, comparés aux sujets âgés sains, les patients modérés avaient des difficultés pour se reconnaître sur des photos récentes, alors qu’aucune différence n’était observée pour les autres périodes de vie. Par contre, aucune différence entre les patients légers et leurs sujets contrôles n’était observée selon l’âge des visages. Par ailleurs, l’analyse des temps de réaction montraient que ces deux groupes de participants étaient plus lents pour reconnaître les photos anciennes par rapport aux photos récentes. Conclusion : La présente étude révèle que les difficultés de reconnaissance des visages évoluent avec l’avancement de la maladie, avec des difficultés qui touchent uniquement la reconnaissance de visages familiers au stade léger de la maladie mais qui s’étendent au propre visage au stade modéré. De plus, une perte graduée dans le temps de la reconnaissance de soi est observée chez les patients modérés (moindre reconnaissance de son visage récent) mais pas chez les patients légers. Au contraire, un ralentissement de la reconnaissance des photos anciennes par rapport aux photos récentes était constaté chez les patients légers ainsi que chez leurs sujets contrôles. Deux hypothèses sont avancées pour expliquer ce phénomène. Premièrement, les photos anciennes provoqueraient une réaction de surprise et par là, augmenteraient le temps de réponse. La seconde hypothèse postule plutôt une difficulté d’accès aux représentations antérieures de soi et de son proche. [less ▲]

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See detailCompeting One-Way Essential Complements : the Forgotten Side of the Net Neutrality Story}
Broos, Sébastien ULg; Gautier, Axel ULg

Conference (2014, June 12)

We examine the incentives of an internet service provider (ISP) to break net neutrality by excluding internet applications competing with its own products, a typical example being the exclusion of VoIP ... [more ▼]

We examine the incentives of an internet service provider (ISP) to break net neutrality by excluding internet applications competing with its own products, a typical example being the exclusion of VoIP applications by a telecom company offering internet and voice services. We show that exclusion is not a concern when the ISP is a monopoly because it can extract the additional surplus created by the application through price rebalancing. By contrast, when ISP’s compete, in an attempt to differentiate, only one ISP will offer the app. Applying a no-exclusion rule in this case can lead to monopoly. [less ▲]

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See detailFélix Fénéon : de l’animation à la naturalisation critique
Saint-Amand, Denis ULg

Conference (2014, June 12)

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See detailExperimental tests and numerical modelling on eight slender steel columns under increasing temperatures
Franssen, Jean-Marc ULg; Zhao, Bin; Gernay, Thomas ULg

in Li, G.Q.; Jiang, S.C.; Chen, Suwen (Eds.) et al Progress on Safety of Structures in Fire (2014, June 11)

In order to fill the lack of knowledge about slender elements behavior at elevated temperatures,, a European research project called FIDESC4 has been funded by the RFCS. This project involves experimental ... [more ▼]

In order to fill the lack of knowledge about slender elements behavior at elevated temperatures,, a European research project called FIDESC4 has been funded by the RFCS. This project involves experimental testing, parametric numerical analyses and development of simple design rules. The present paper reports the characteristics and the results of the FIDESC4 experimental test campaign performed at the University of Liege on slender steel columns at elevated temperatures. A total of eight columns have been tested, all of them with I shape section. Six columns were made of welded sections (some prismatic and some tapered members) and two columns were with hot rolled sections. The nominal length of the columns was 3 meters with the whole length being heated. The strength of the material (webs and flanges) was measured on sample before the tests. The order of magnitude of the initial geometrical imperfections was recorded. The columns were not restrained against longitudinal thermal elongation. The supports at the ends were cylindrical thus inducing a restrain against rotation in one plane while allowing rotation in the other plane. The allowed direction of rotation was chosen in each test to induce buckling around the strong or the weak axis. The load was applied at ambient temperature and maintained for a period of 15 minutes after which the temperature was increased under constant load. The load was applied concentrically on some tests and with an eccentricity in other tests. The load eccentricity was either applied at both ends, leading to constant bending moment distribution along the length, or at one end only, leading to a triangular bending moment distribution. Heating was applied by electrical resistances enclosed in ceramic pads. The columns and the ceramic pads were wrapped in ceramic wool insulating material. This technique was preferred to gas heating in a standard test furnace because it allows applying a slower and better controlled heating rate and thus obtaining a more uniform temperature distribution in the member. It is also easier to measured lateral displacements of the column. Preliminary blank tests were performed on unloaded specimen in order to determine the heating range to be used later on the loaded columns. The paper will also report on a modification of the heating technique that was applied and improved significantly the uniformity in the temperature distribution. Numerical simulations were performed before the tests using shell elements of the software SAFIR and assumed values of the material properties in order to predict the failure modes. It was essentially crucial to determine whether lateral supports at intermediate levels should be provided in order to ensure failure in the desired direction. Experience showed that the failure modes developed as predicted by the numerical simulations. Besides a thorough description of the experiments, the paper will also present the obtained results in terms of failure mode, ultimate temperature and evolution of longitudinal and transverse displacement. Some information will also be given about the level of detail that has to be used in the numerical model in order to get accurate results at a reasonable price. [less ▲]

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See detailInternet : support, médium ou épimédium ?
Barnabé, Fanny ULg; Dozo, Björn-Olav ULg

Conference (2014, June 11)

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See detailSoil infrastructure evolution and its effect on water transfer processes under contrasted tillage systems - overview of methodologies with preliminary results
Parvin, Nargish ULg; Colinet, Gilles ULg; Garré, Sarah ULg et al

Conference (2014, June 10)

The heterogeneity of soil structure and porosity are highly influenced by external factors like tillage systems and other land management approaches. The aim of this project is to investigate the effect ... [more ▼]

The heterogeneity of soil structure and porosity are highly influenced by external factors like tillage systems and other land management approaches. The aim of this project is to investigate the effect of soil tillage along with residue management on the changing pattern of soil structure. This investigation will help to emphasize the different water flow dynamics especially the preferential flow processes through the soil that are influenced by the changes in structural distribution in the soil profile. The experimentation has been started from June 2013 in the research field in Gembloux. Soil profile description together with soil sampling has been carried out in the four objects of land management. Soil samples will be used for the measurement of water retention capacity (done), hydraulic conductivity and x-ray microtomography. The assessment of soil water retention curves with pressure plate technique show significantly (p<0.05) higher water retention (Hwr) in WP than ST at 9.8 to 98 hPa, Hwr in WP than NI at 39 to 14710 hPa, Hwr in ST than NI at 294 to 14710 hPa and Hwr in WP than NO at 69 to 98 hPa. There was no significant difference in the water retention between NO and NI and ST and NO. Since, tillage practices generally increase soil porosity, the correlation between soil hydraulics and porosity distribution would expect to be different for different tillage systems. In our study, WP retains more water due to the increase of macroporosity than ST, NI and NO. As the changes in soil structure are usually noticed in the range of 9.8 to 98 hPa, so, we can conclude that there is certainly structural change between WP and conservation practices of ST, NI and NO. In our study, there will be also soil moisture sensors (Decagon 10HS, 5TM and ML3 Thetaprobe) to capture the total soil moisture networks in the field under four different trials. The soils from the different trials and also from different depths (0-15, 25-30 and 50-60 cm) were used for zone specific calibration of the sensors. All the experiments will be repeated twice a year. For the specific spatio-temporal comparison, the monitoring results from electrical resistance tomography will be available from the collaborated project of the same faculty. [less ▲]

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See detailLes remèdes d'origine égyptienne utilisés dans la médecine vétérinaire antique
Marganne, Marie-Hélène ULg

Conference (2014, June 10)

Famous since the Odyssey (IV, 229-230) for its drugs, Egypt furnishes the Greek world with some medical substances already mentioned in the hippocratic treatises. Moreover, many Greek drug names have been ... [more ▼]

Famous since the Odyssey (IV, 229-230) for its drugs, Egypt furnishes the Greek world with some medical substances already mentioned in the hippocratic treatises. Moreover, many Greek drug names have been loaned from the Egyptian language, such as ἄμ(μ)ι for cumin, κίκι for castor-oil, κόμμι for gum, κῦφι for a complex preparation used for fumigation in cult practices, νίτρον for sodium carbonate, στίμμι for galena, σῶρυ for ferrous sulfate, and σάμψ(ο)υχον, for marjoram, whose name means “herb (sem) of Soukhos", another name for the crocodile god Sobek. The trade of drugs, spices and colourants, used in pharmacology, cosmetology, painting, cultual and magical practices, embalming rites and nutrition always flourished in Egypt and has intensified in Hellenistic and Roman times. As a continuation of the research on remedies of Egyptian origin in Greco-Roman pharmacopoeia, this article provides a list of Egyptian ingredients used in Greek and Latin veterinary prescriptions. The use of these substances is compared with recomandations from human medicine. Their availability and costs are also studied. [less ▲]

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See detailHigher Symmetries of the conformal Laplacian
Radoux, Fabian ULg

Conference (2014, June 09)

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See detailFe and Mg Isotope Fractionation in Olivine from the NWA 1068 Shergottite
Collinet, Max ULg; Charlier, Bernard ULg; Namur, Olivier et al

Conference (2014, June 09)

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See detailGround-based transmission spectrum of WASP-80 b, a gas giant transiting an M-dwarf
Delrez, Laetitia ULg; Gillon, Michaël ULg; Lendl, Monika ULg et al

Poster (2014, June 09)

We present here some results from our ground-­based multi-­object spectroscopy program aiming to measure the transmission spectrum of the transiting hot Jupiter WASP-80b using the VLT/FORS2 instrument ... [more ▼]

We present here some results from our ground-­based multi-­object spectroscopy program aiming to measure the transmission spectrum of the transiting hot Jupiter WASP-80b using the VLT/FORS2 instrument. WASP-­80b is a unique object as it is the only known specimen of gas giant orbiting an M-dwarf that is bright enough for high SNR follow-­up measurements. Due to the nature of its host star, this hot Jupiter is actually more `warm' than `hot', with an estimated equilibrium temperature of only 800K. It is thus a prime target to improve our understanding of giant exoplanet atmospheres in this temperature range. [less ▲]

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See detailEffects of tillage practices and crop residue exportation on earthworm communities and soil physico-­chemical properties in silt loam arable soil (Belgium)
Lemtiri, Aboulkacem ULg; Colinet, Gilles ULg; Alabi, Taofic ULg et al

Poster (2014, June 08)

Earthworms are known to play integral roles in soils, and are often referred to as vital soil and ecosystem engineers due to their capacity to influence a wide range of chemical, physical, and biological ... [more ▼]

Earthworms are known to play integral roles in soils, and are often referred to as vital soil and ecosystem engineers due to their capacity to influence a wide range of chemical, physical, and biological properties of soil environments. Therefore, it is important to understand how earthworm communities are impacted by tillage systems and crop management practices. In the present study, earthworm and soil samples were collected from wheat cultivated fields in Gembloux, Belgium under the following four experimental treatments: (1) conventional tillage with crop residues left in the soil (CT/IN); (2) conventional tillage with crop residues removed from the field (CT/OUT); (3) reduced tillage with crop residues left in the soil (RT/IN); and (4) reduced tillage with crop residues removed from the field (RT/OUT). The different tillage systems were applied for four consecutive years prior to the initiation of the current study. Results indicated soil compaction was significantly higher in RT compared with CT up to a depth of 6–49 cm. Significant differences were not detected between residue incorporation depth systems, where results showed mean earthworm abundance was respectively 182.25 and 180 individuals.m-2 in CT and RT. Mean earthworm biomass was similarly not significantly different between CT and RT, where results were respectively 48.52 and 57.27 g.m-2. However, a significant difference was observed between IN and OUT treatments, suggesting the exportation of wheat residues will limit earthworm abundance and biomass in CT and RT plots. Data showed high representation of the endogeic earthworm ecological category, notably N. c. caliginosus regardless of treatment. Despite tillage system and exportation of crop residues, N. c. caliginosus, L. terrestris, and A. r. rosea exhibited high abundance, indicating tolerance to soil environmental conditions. For each depth, measures of soil physico-chemical properties showed significant differences among treatments. Furthermore, soil chemical property attributes were significantly higher in the first soil centimetres compared to lower soil layers. These results were attributable to earthworm activity and wheat residues, suggesting earthworms contributed to nutrient dynamics, particularly at increased soil depths. Overall, the results emphasise the influence of exportation of crop residues on earthworm community and also, the important influence of earthworm activity on soil physico-chemical properties change, processes which are closely linked. [less ▲]

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See detailFast Ambient Pressure Thermal cycling of space solar arrays samples under equivalent AM0 illumination conditions
Guiot, Marc ULg; Fernandez Lisbona, Emilio; Witteveen, Bob et al

Conference (2014, June 08)

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See detailA wavelet-based analysis of surface air temperature variability
Deliège, Adrien ULg; Nicolay, Samuel ULg

Conference (2014, June 06)

We study the Hölder regularity of surface air temperature signals using the wavelet leaders method (WLM). This method has been successfully applied in several domains such as DNA analysis, fully ... [more ▼]

We study the Hölder regularity of surface air temperature signals using the wavelet leaders method (WLM). This method has been successfully applied in several domains such as DNA analysis, fully developped turbulence analysis, internet data traffic analysis,... to name just a few, and we now use it in climatology. We first define the notions of Hölder exponent, monofractal functions and spectrum of singularities before explaining the WLM. Then we use it to study surface air temperature signals from weather stations spread across Western and Eastern Europe and show that they are monofractal, i.e. their irregularity (in the sense of variability) is regular. After, we show that the stations can be classified according to their Hölder exponent and that this classification matches with the worldwide used Köppen-Geiger climate classification. A blind test is performed in order to confirm the results, which can be partly explained by the influence of the North Atlantic Oscillation. Our results can be helpful to test the accuracy of current climatic models. [less ▲]

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See detailSolar irradiance modelling over Belgium using WRF-ARW : A sensitivity analysis of Mellor-Yamada-Nakanishi-Niino (BYNN) boundary layer scheme parameters
Beaumet, Julien ULg; Doutreloup, Sébastien ULg; Fettweis, Xavier ULg et al

Conference (2014, June 06)

Global solar irradiances at ground level are modelled over Belgium using latest version of WRF-ARW regional climate model (RCM). The model set-up used has a resolution of 5 kilometres. The boundary layer ... [more ▼]

Global solar irradiances at ground level are modelled over Belgium using latest version of WRF-ARW regional climate model (RCM). The model set-up used has a resolution of 5 kilometres. The boundary layer scheme chosen is the Mellor-Yamada-Nakanishi-Niino (MYNN) 2.5 scheme with the Turbulent Kinetic Energy (TKE) closure proposed by Canuto et al., (2008) and Kitamura (2010). In this scheme, the modification of some parameters allows to change the determinant mixing length (surface layer, planet boundary layer, top of boundary layer/entrainment) which then modifies heat and moistures fluxes produced by turbulent mixing. Such modifications have significant influences on modelled cloudiness and therefore on modelled global solar irradiance incoming at the surface. The present study proposes a sensitivity analysis of the different parameters that influence the mixing length ('alp1' to 'alp5') and the TKE diffusion ('Sqfac') in order to find the most suitable constant values of these parameters for the modelling of cloudiness over Belgium. Results of different simulations are compared with global solar irradiance measurements performed by the Centre Spatial de Liège at Sart-Tilman in 2013 and 2014. Firsts results show that the dry bias frequently found when using WRF-ARW with standard set-ups can be greatly reduced thanks to an increased modelled cloudiness. The quantitative and qualitative effects of these modifications over cloudiness are also analysed by displaying 2D representation of modelled clouds over Sart-Tilman and confronting them with on-site observations. [less ▲]

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See detailLe sort des travailleurs d’une entreprise en réorganisation judiciaire
Kéfer, Fabienne ULg; Gailliet, Guillaume ULg

in Clesse, Jacques (Ed.) Questions choisies de droit social. Hommage à Michel Dumont (2014, June 06)

Le droit de l’entreprise en difficulté entretient avec le droit du travail des liens tendus. La préservation du potentiel économique de l’entreprise s’affronte aux dispositions visant à éviter la ... [more ▼]

Le droit de l’entreprise en difficulté entretient avec le droit du travail des liens tendus. La préservation du potentiel économique de l’entreprise s’affronte aux dispositions visant à éviter la dégradation de la situation des travailleurs. Le complexe normatif étudié reflète le point actuel du rapport de force entre le monde économique et les syndicats. Les salariés sont, en définitive, amenés à faire une grande partie du sacrifice nécessaire pour atteindre l’objectif économique recherché. Ce constat est perceptible dans l’hypothèse d’une réorganisation par accord collectif et dans celle du transfert sous autorité de justice, qui témoignent des rapports complexes entre les intérêts économiques et sociaux. La conciliation de ces intérêts divergents s’effectue sous la surveillance du juge. [less ▲]

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See detailOn-the-fly domain adaptation of binary classifiers
Pierard, Sébastien ULg; Marcos Alvarez, Alejandro ULg; Lejeune, Antoine ULg et al

in 23rd Belgian-Dutch Conference on Machine Learning (BENELEARN) (2014, June 06)

This work considers the on-the-fly domain adaptation of supervised binary classifiers, learned off-line, in order to adapt them to a target context. The probability density functions associated to ... [more ▼]

This work considers the on-the-fly domain adaptation of supervised binary classifiers, learned off-line, in order to adapt them to a target context. The probability density functions associated to negative and positive classes are supposed to be mixtures of the source distributions. Moreover, the mixture weights and the priors are only available at runtime. We present a theoretical solution to this problem, and demonstrate the effectiveness of the proposed approach on a real computer vision application. Our theoretical solution is applicable to any classifier approximating Bayes' classifier. [less ▲]

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See detailComparison between wind speed observed at 100m height and wind speeds simulated by the WRF and MAR models
Doutreloup, Sébastien ULg; Fettweis, Xavier ULg; Erpicum, Michel ULg et al

Poster (2014, June 06)

In the context of FLEXIPAC project funded by "RELIABLE" program of Walloon Region (Belgium), the Laboratory of Climatology and Topoclimatology (LCT) of the University of Liège (Belgium) aims to adjust the ... [more ▼]

In the context of FLEXIPAC project funded by "RELIABLE" program of Walloon Region (Belgium), the Laboratory of Climatology and Topoclimatology (LCT) of the University of Liège (Belgium) aims to adjust the WRF regional model (v.3.4.) forced by ERA-Interim model. Our analysis shows that wind speeds at 100m height simulated by WRF are systematically overestimated compared to wind speeds extracted from wind productions of two wind farms. In order to identify this problem, four comparisons were performed in this contribution. Firstly, we compare WRF model with reanalysis based forcing model. Secondly, we compare two WRF simulations, where one of them has a more precise spatial resolution. Thirdly, we smooth WRF outputs in time (6-hr running mean) in order to study the accuracy of the 30-min variability generated by WRF model. Finally, we comp compare the WRF model with the MAR (v3.3.) regional model using the same forcing at its lateral boundaries. This last one seems to suggest that the MAR model better simulates wind speeds at 10m and at 100m than WRF model and then that wind speed underestimation by WRF is well linked to the WRF physics itself. [less ▲]

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See detailMuti-scale methods with strain-softening: damage-enhanced MFH for composite materials and computational homogenization for cellular materials with micro-buckling
Wu, Ling ULg; Nguyen, Van Dung ULg; Adam, Laurent et al

Conference (2014, June 06)

In this work, multi-scale methods with strain softening are developed in the contexts of damage modeling for composite laminates and of buckling analyses in cellular materials. First, an anisotropic ... [more ▼]

In this work, multi-scale methods with strain softening are developed in the contexts of damage modeling for composite laminates and of buckling analyses in cellular materials. First, an anisotropic gradient–enhanced continuum damage model is embedded in a mean–field homogenization (MFH) process for elasto-plastic composites. The homogenization procedure is based on the newly developed incremental secant mean-field homogenization formulation, for which the residual stress and strain states reached in the phases upon a fictitious elastic unloading are considered as starting point to apply the secant method. The mean stress fields in the phases are then computed using isotropic secant tensors, which are naturally used to define the Linear Comparison–Composite The resulting multi– scale model is then applied to study the damage process at the meso–scale of laminates, and in particular the damaging of plies in a composite stack. By using the gradient–enhanced continuum damage model, the problem of losing uniqueness upon strain softening is avoided. Second, an efficient multi–scale finite element framework capturing the buckling instabilities in cellular materials is developed. As a classical multi–scale computational homogenization scheme loses accuracy with the apparition of the macroscopic localizations resulting from the micro–buckling, the second order multi–scale computational homogenization scheme is considered. This second–order computational framework is enhanced with the following novelties so that it can be used for cellular materials. At the microscopic scale, the periodic boundary condition is used because of its efficiency. As the meshes generated from cellular materials exhibit a large void part on the boundaries and are not conforming in general, the classical enforcement based on the matching nodes cannot be applied. A new method based on the polynomial interpolation2 without the requirement of the matching mesh condition on opposite boundaries of the representative volume element (RVE) is developed. Next, in order to solve the underlying macroscopic Mindlin strain gradient continuum of this second–order scheme by the displacement–based finite element framework, the treatment of high order terms is based on the discontinuous Galerkin (DG) method to weakly impose the C1-continuity. Finally, as the instability phenomena are considered at both scales of the cellular materials, the path following technique is adopted to solve both the macroscopic and microscopic problems. [less ▲]

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See detail[18F]UCB-H AS A NEW PET RADIOTRACER FOR SYNAPTIC VESICLE PROTEIN 2A
Bahri, Mohamed Ali ULg; Bastin, Christine ULg; Aerts, Joël ULg et al

Poster (2014, June 06)

Synaptic vesicle protein 2A (SV2A) is widely distributed in the brain and has been demonstrated to be involved in vesicle trafficking. The critical role of SV2A in proper nervous system function is shown ... [more ▼]

Synaptic vesicle protein 2A (SV2A) is widely distributed in the brain and has been demonstrated to be involved in vesicle trafficking. The critical role of SV2A in proper nervous system function is shown, for example, by the fact that it is a binding site and the primary mechanism of levetiracetam. Levetiracetam is an antiepileptic drug which has recently been suggested to reduce synaptic deficits in a mouse model for Alzheimer’s disease and to improve cognition in patients with amnestic mild cognitive impairment. We here aimed to investigate the cerebral distribution of [18F]UCB-H, a fluorine-18 radiolabelled PET imaging tracer, which has a high affinity with the SV2A. [18F]UCB-H was radiosynthesized under GMP conditions. Dynamic PET data of the head of four healthy volunteers were acquired over 100 minutes after injection of 170.4 ± 24.9 MBq of [18F]UCB-H. The arterial input function was obtained by blood sampling during the dynamic PET acquisition. The analysis of the blood data reveled a consistent amount of [18F]UCB-H in whole blood and plasma which indicates a very low degree of binding of the tracer to the red blood cells. The unchanged fraction of [18F]UCB-H in plasma showed a bi-exponential behavioral decrease with a starting fraction of 92% of the injected amount of the tracer, measured at 3 min post injection. This fraction decreased to about 50% at 10 min post injection. The [18F]UCB-H PET data showed a high and rapid uptake in the grey matter structures, matching the known ubiquitous distribution of the SV2A in the brain. The kinetics of the tracer in the brain was characterized by an initial high uptake phase followed by rapid washout allowing the standard compartmental modeling (1-tissue compartment, 2-tissue compartment, and Logan graphical analysis). The three models gave consistent results. The two-tissue compartment model fitted the experimental data best and provided a total distribution volume of the [18F]UCB-H in the brain greater than 7 mL/cm3 and a specific distribution volume around 3 mL/cm3. Our results suggest that [18F]UCB-H is a good candidate as radiotracer for brain SV2A proteins and could be used for human studies. In the future, SV2A modifications might be assessed in neurological pathologies such as Alzheimer’s disease. [less ▲]

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See detailLa psychopathologie à la lumière des histoires de vie : Etude de la fonction narrative d’adolescents obèses et dépressifs.
Jadin, Aurore ULg; Gauthier, Jean-Marie ULg; Boulard, Aurore ULg

in Née, Emilie; Daube, Jean-Michel; Valette, Mathieu (Eds.) et al Proceedings-Actes des 12èmes journées internationales d'analyse statistique de données textuelles (2014, June 05)

Obesity in adolescence is a complex chronic illness with havy consequences in short, medium and long terms, both in terms of physical health and mental health, disturbing the body and identity of these ... [more ▼]

Obesity in adolescence is a complex chronic illness with havy consequences in short, medium and long terms, both in terms of physical health and mental health, disturbing the body and identity of these youngs (High Authority of Health, 2011; Nietsen and Bruwier, 2007). The literature mentions depression as a pathology associated with obesity. Some researchers consider obesity as a cause of depressive symptoms while others researchers see depression like a risk factor for excessive weight gain (Blaine, 2008). Depression in adolescence has been the subject of epidemiological studies for some years. In adolescents, the prevalence rates vary from 5 to 7 % for major depressive episode (MDE) with a prevalence of 2 girls for one boy (Alvin and Marcelli, 2005). The specific symptoms of depressed mood are present in 30-40 % of schooled adolescents (Boulard et al., 2012). During adolescence, the individual acquires the ability to link the various elements of one’s life and build a coherent life story. The adolescent will write one’s story in a personal context. According to Habermas et al. (2008), both the form and the content of life stories show how the individual integrates the lived experiences in a coherent whole. Based on the statistical analysis of textual data, we compared the life stories of 28 obese adolescents, depressed schooled adolescents, depressed hospitalized adolescents and control ones. The first results show specific structures and particular contents depending on these groups. The use of pronouns, temporal markers and the reported events differ by groups. Beyond clinical results, this research also highlights the interest of statistical analysis of textual data (ADT) to improve the understanding of adolescent’s psychopathology. [less ▲]

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See detailLa charge de confesseur princier au XVIIème siècle, une définition controversée
Pirlet, Pierre-François ULg

Conference (2014, June 05)

Si la mission d'un confesseur au début du XVIIème siècle est strictement définie par les textes canoniques du catholicisme comme celle d'un administrateur de sacrement, la définition des tâches revenant ... [more ▼]

Si la mission d'un confesseur au début du XVIIème siècle est strictement définie par les textes canoniques du catholicisme comme celle d'un administrateur de sacrement, la définition des tâches revenant au confesseur du Prince est étonnamment lâche. Du premier, on attendait qu'il jugeât les actes de son pénitent, propose une consolation – sous la forme d'exercices expiatoires – destinés à le réconcilier avec Dieu, et offre une direction spirituelle visant à prévenir les rechutes dans le péché. Mais confesser le Prince contraignait le religieux qui s’y attelait à un exercice bien plus complexe. Il lui revenait de juger et d'apporter une direction de conscience aux deux personnes du roi : l'humaine et l'institutionnelle. En effet, il eût été impossible de distinguer formellement l'âme du souverain de celle du mortel. De même, il échoyait au confesseur de conseiller son pénitent quant à l'aspect moral de ses décisions, que celles-ci n'impliquèrent que sa personne, ou au contraire l'ensemble des territoires et des sujets sous sa conduite. De cette difficulté naquit une controverse quant à l'implication nécessaire et raisonnable du confesseur princier dans les affaires temporelles : la papauté, les rois d'Espagne, les ecclésiastiques de cour madrilènes, les gouverneurs-généraux des Pays-Bas et les supérieurs des ordres religieux dont étaient issus les confesseurs – et particulièrement la Compagnie de Jésus – proposèrent tous une définition différente – et controversée – des prérogatives de ce religieux au cœur du pouvoir. En prenant appui sur la situation des confesseurs de la cour de Bruxelles durant la grande première moitié du XVIIème siècle, nous tâcherons au travers de cette communication de proposer un aperçu global des différentes définitions de la confession princière telles que défendues par les contemporains. Notre exposé proposera en outre un rapide regard sur les deux approches utilisées par les historiens pour reconstituer les différentes définitions de la charge : à la patiente collecte et à l'analyse des traces laissées dans les sources par l'activité au quotidien des confesseurs (approche bottom-up) se confronte une méthode cherchant une définition d'époque des prérogatives de ces religieux faisant autorité (approche top-down). Nous constaterons que ces deux approches, qui ne s'opposent pas, s’accommodent néanmoins difficilement l'une à l'autre, créant ainsi une controverse non plus dans l'objet, mais dans la méthode. [less ▲]

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See detailDesign and synthesis of high-affinity ligands of AMPA receptors and study of their Fluorine-18 radiolabeling
Deverdenne, François ULg; Goffin, Eric ULg; Plenevaux, Alain ULg et al

Poster (2014, June 05)

The AMPA subtype of glutamatergic receptors is the main actor in the excitatory neurotransmission in the mammalian central nervous system. These receptors are involved in the expression and the ... [more ▼]

The AMPA subtype of glutamatergic receptors is the main actor in the excitatory neurotransmission in the mammalian central nervous system. These receptors are involved in the expression and the maintenance of the long-term potentiation, a phenomenon closely linked to cognitive and memorization processes. Based on experimental data collected in recent years, the use of AMPA potentiators seems to be an interesting approach in the treatment of cognitive deficits (e.g. Alzheimer disease), schizophrenia or depression. Such AMPA signal potentiation could be mediated by positive allosteric modulators (PAMs) of the AMPA receptors, a class of compounds able to produce a fine signal tuning in the presence of the endogenous ligand in the synapse, providing less toxicity than direct agonists. With this approach, the laboratory of Medicinal Chemistry of Liège university developed many series of AMPA potentiators , among which 1,2,4-benzothiadiazine 1,1-dioxides (BTDs). In order to better understand the in vivo mapping of AMPA receptors and its evolution in neurological diseases, the present work aims at developing the design and the synthesis of BTDs positive allosteric modulators radiolabeled with a fluorine-18 atom. Based on previously synthesized series in this field, we investigate the synthesis of a new class of high-affinity AMPA potentiators characterized by the presence of a fluorine atom at selected positions on the structure of the AMPA potentiators. Thanks to in vitro pharmacological evaluations, we will further determine the best candidates for their fluorine-18 radiolabeling. [less ▲]

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See detailExploration du récit de vie d’adolescents
Poudat, Céline; Boulard, Aurore ULg

in Née, Emilie; Daube, Jean-Michel; Valette, Mathieu (Eds.) et al Proceedings-actes des 12èmes journées d'analyse statistique de données textuelles (2014, June 05)

The present paper follows on from the research we presented in previous JADT (Boulard, Poudat, Gauthier 2012). We still focus on the development of narrative competence (Habermas et Bluck 2000) in ... [more ▼]

The present paper follows on from the research we presented in previous JADT (Boulard, Poudat, Gauthier 2012). We still focus on the development of narrative competence (Habermas et Bluck 2000) in children and adolescents. Although children develop narrative skills, life narratives only emerge in adolescence. On the basis of a corpus made of spontaneous oral speech, we had empirically demonstrated that pre-adolescents aged of 12 had developed stabilized narrative skills enabling them to produce life narratives. Here, we propose a first exploration of the overall structure of adolescent life stories, thanks to a corpus of 268 oral self narratives completed with a questionnaire. [less ▲]

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See detailLIGAND-INDEPENDENT IDENTIFICATION OF ORPHAN GPCR ARRESTIN BINDING
Dupuis, Nadine ULg; Gilissen, Julie ULg; Derj, Anouar ULg et al

Poster (2014, June 05)

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See detailApproche lexicométrique des controverses climatiques
Scotto d'Apollonia, Lionel; Luxardo, Giancarlo; Piet, Grégory ULg

Poster (2014, June 05)

D’un point de vue historique, les controverses climatiques prennent racine à la fin du XIXe siècle et se sont déployées tout au long du XXe siècle. Elles prennent toutefois une tournure plus politique, en ... [more ▼]

D’un point de vue historique, les controverses climatiques prennent racine à la fin du XIXe siècle et se sont déployées tout au long du XXe siècle. Elles prennent toutefois une tournure plus politique, en ce début de XXIe siècle, en ce sens que le débat climatique « se priorise » dans les agendas politiques des Etats européens, de manière générale. Si les études sur les controverses climatiques tendent, certes, à se développer de plus en plus actuellement, l’approche linguistique demeure peu investie par rapport au potentiel analytique qu’elle pourrait apporter à la recherche sur le sujet. L’une des rares études lexicométriques concernant le climat est celle réalisée par Lamria Chetouani dont le corpus de textes s’étend de 1989 à 1990. Il faut aussi prendre en compte les travaux de Francis Chateauraynaud, qui a entrepris une démarche destinée au traitement des controverses s'appuyant sur un ensemble de techniques : la socio-informatique. Inscrit dans un cadre d’analyse socioépistémique des controverses socioscientifiques et en se basant sur un corpus de textes choisis autour de la période 2009 - 2010, notre article propose donc d'associer une analyse socio-informatique des controverses climatiques avec une utilisation d'outils lexicométriques. En nous concentrant sur le traitement discursif de quelques notions-clés, notamment l'incertitude et le risque, nous cherchons à croiser les résultats fournis par la lexicométrie (logiciel Lexico) avec ceux fournis par la socio-informatique (logiciel Prospero). En conclusion, nous ouvrons un espace de discussion sur les modes opératoires permettant d'articuler les deux approches. [less ▲]

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See detailLes médiateurs scolaires en action : des discours aux pratiques
Dethier, Baptiste ULg

Conference (2014, June 05)

En 1993, dans un contexte marqué les questions d’insécurité, de violence scolaire, de crise de confiance envers les institutions ou encore de décrochage scolaire, 28 médiateurs sont engagés dans autant ... [more ▼]

En 1993, dans un contexte marqué les questions d’insécurité, de violence scolaire, de crise de confiance envers les institutions ou encore de décrochage scolaire, 28 médiateurs sont engagés dans autant d’établissements scolaires aux publics défavorisés de la région bruxelloise. Ce projet pilote, voyant le jour sous la houlette du Ministère de l’enseignement, ne sera institutionnalisé qu’en 1998 dans un décret créant le Service de Médiation Scolaire, divisé en deux entités : 56 médiateurs internes à Bruxelles et 30 médiateurs externes (répartis par zones couvrant plusieurs établissements) en Wallonie. Par ailleurs, d’autres niveaux de pouvoir (communes, diocèses, écoles) créaient également, localement, leurs propres fonctions de médiateur scolaire. Actuellement, on en dénombre environ 120 en Belgique francophone. Ce nouvel acteur, bien que peu étudié, incarnerait un nouveau mode de régulation sociale (Bonafé-Schmitt, 1996) remettant en question les équilibres historiques du système scolaire (Verhoeven, 1997). En effet, il se présente comme un tiers neutre et indépendant de l’établissement, permettant ainsi la création d’un espace où peuvent se résoudre différents problèmes concernant les personnes demandeuses, qu’elles soient élèves, membres du personnel scolaire ou encore parents. Dans un premier temps, notre attention se porte sur l’ensemble des acteurs portant le nom de médiateurs scolaires (Kuty et al., 2012). Au sein d’un cadre légal ne définissant que vaguement leur fonction, ces derniers sont néanmoins globalement chargés de prévenir la violence et le décrochage scolaires et de favoriser, conserver ou rétablir le climat de confiance entre élèves, écoles et familles. À partir de là, ils ont progressivement construit leurs propres pratiques et leur identité, cherchant par là à trouver et à consolider leur place au sein d’un milieu scolaire déjà marqué par la présence de multiples acteurs. Dans un second temps, des études de cas approfondies dans six établissements d’enseignement secondaire permettent de constater que les médiateurs ne disposaient pas du monopole de la médiation (Dubois et Dethier, 2013), concept polysémique auquel de nombreux acteurs se réfèrent pour qualifier certains aspects de leur travail quotidien. En outre, le recours à la médiation ou aux médiateurs ne se révèle être qu’une solution parmi d’autres pour faire face aux différents problèmes rencontrés par les acteurs : violence, décrochage, absentéisme, échec scolaire, conflits, problèmes socio-économiques… Ces constats exigent une étude empirique approfondie du travail concret réalisé par les médiateurs scolaires, une étude attentive à leurs discours mais aussi à l’observation de leurs pratiques et interactions directes avec les différents acteurs scolaires. Les résultats de cette étude font l’objet de cette communication. Cette contribution se base sur un corpus composé de onze entretiens individuels, trois focus groups et trois périodes d’observation non participante auprès de médiateurs belges francophones membres d’un même service. Ces derniers revendiquent une posture de tiers neutre et indépendant dans l’école, ainsi que des principes basés sur le non-jugement, la confidentialité, l’accueil inconditionnel de la demande ou encore la non-expertise. Il s’agira par conséquent de rendre compte de la manière dont ces médiateurs traduisent leurs discours en pratiques au quotidien. [less ▲]

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See detailMALDI Mass Spectrometry Imaging: a new tool to decipher the antibiome of Bacillus amyloliquefaciens
Debois, Delphine ULg; Jourdan, Emmanuel; Cawoy, Hélène et al

Conference (2014, June 05)

Soil Bacillus isolates may devote up to 8% of their genome to nonribosomal synthesis of lipopeptide (LP)- and polyketide (PK)-type antibiotics. LPs from surfactin, iturin and fengycin families are known ... [more ▼]

Soil Bacillus isolates may devote up to 8% of their genome to nonribosomal synthesis of lipopeptide (LP)- and polyketide (PK)-type antibiotics. LPs from surfactin, iturin and fengycin families are known to exert different actions on the wellness of the producing strain such as fungitoxicity (iturin, fengycin) or motility, root colonization and immune stimulating agent (surfactin). Nevertheless, few is reported about the actual antibiome secreted in situ by Bacillus cells during confrontation with phytopathogens or plant root colonization. We developed a method mimicking the conditions prevailing in the rhizosphere and, taking advantage of the versatility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging, we were able to localize and identify antibiotics produced in situ by bacterial cells. First, we applied this new methodology to bioassays in which Bacillus amyloliquefaciens 98S were grown together with Fusarium oxysporum, with the aim of deciphering the role of the different LP families during the phytopathogen growth inhibition. Our results showed that the three LP families were readily produced in different proportions. Especially, images of surfactins, iturins and fengycins demonstrated that iturins are the antibiotic family actually involved in the antagonism against Fusarium oxysporum. In a second approach, we used a “in planta” model in which Bacillus amyloliquefaciens S499 was simultaneously grown with Tomato and Arabidopsis thaliana roots. Imaging results, obtained during a time course analysis, showed that surfactin is always the major lipopeptide detected. In further experiments involving a refined time-window, we observed that surfactin is actually produced as soon as 24h post inoculation. These results were the starting point of a wider study showing that the early accumulation of surfactin is a complex phenomenon involving, among other mechanisms, cell-well components recognition by bacteria, and that this interaction is a win-win association for both plant and bacterial cells. [less ▲]

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See detailFunctional study of the Ser/Arg-rich splicing factor SRSF5a during zebrafish embryonic development
Joris, Marine ULg; Muller, Marc ULg; Motte, Patrick ULg

Poster (2014, June 05)

Nuclear pre-mRNA splicing is a key process regulating gene expression in eukaryotes. Splicing consists in the removal of introns and the joining of exons within a dynamic macromolecular complex called the ... [more ▼]

Nuclear pre-mRNA splicing is a key process regulating gene expression in eukaryotes. Splicing consists in the removal of introns and the joining of exons within a dynamic macromolecular complex called the spliceosome, which consist of five small nuclear ribonucleoproteins (snRNPs) and numerous non snRNPs proteins (1). Amongst these non snRNPs proteins, the SR proteins family constituted an important group of splicing factors that are involved in constitutive and alternative splicing (2,3). SR proteins are structurally related as they are characterized by one or two RNA-recognition motifs (RRMs) in N-ter and a C-terminal domain enriched in dipeptide Ser/Arg. Phylogenetic inference using the RRM domain allowed us to identify 13 encoding genes for SR proteins in the vertebrate model organism, Danio rerio. The Zebrafish is increasingly recognized as a powerful model for the study of vertebrate embryonic development in a physiological context. The roles of SR splicing factors during animal cell differentiation and development are largely unknown. The aim of the present research is to investigate SR proteins functions during zebrafish development by using molecular and genetic approaches. In this study, we investigated the role of the SR splicing factor SRSF5a. The expression profile was determined by in situ hybridization at 24, 48 and 72 hours post-fertilization and showed SRSF5a expression mainly in brain, retina and pharyngeal arches at these stages. Furthermore, SRSF5a knock-down by morpholinos microinjection strongly suggests an important role of this specific splicing factor during eyes and brain development. In order to gain insight into the molecular function of SRSF5a, we analysed control and morphant transcriptomes using high throughput RNA sequencing. Finally, we use a complementary approach to morpholinos and generate SRSF5a mutant fishes using TALENs (Tal effector nucleases)(4,5). 1. Wahl MC, Will CL, & Luhrmann R (2009) The spliceosome: design principles of a dynamic RNP machine. Cell 136(4):701-718. 2. Long JC & Caceres JF (2009) The SR protein family of splicing factors: master regulators of gene expression. Biochem J 417(1):15-27. 3. Graveley BR (2000) Sorting out the complexity of SR protein functions. RNA 6(9):1197-1211. 4. Moore et al. (2012) Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs). Plos One 120(1):1-12. 5. Cade et al (2012) Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs. Nucleic acid research Vol 40, No 16:8001-8010. [less ▲]

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See detailBiorefine: Recovery of nutrients and metallic trace elements from different wastes by chemical and biochemical processes
Tarayre, Cédric ULg; Fischer, Christophe ULg; De Clercq, Lies et al

Conference (2014, June 05)

At present, most waste processing operations are not oriented towards the valorization of valuable reusable components such as nitrogen, phosphorus, potassium and even Metallic Trace Elements (MTEs ... [more ▼]

At present, most waste processing operations are not oriented towards the valorization of valuable reusable components such as nitrogen, phosphorus, potassium and even Metallic Trace Elements (MTEs). Currently, sewage sludge, for example is usually used as a fertilizer in agriculture, in energy production or in the field of construction. Ashes originating from sludge incineration contain heavy metals and minerals in large quantities. Manure is mainly used in agriculture, although considerable amounts of nutrients are lost and cause pollution. Digestate is also used in agriculture, but other alternatives have been proposed, such as the energetic valorization. Better valorization of these wastes in agriculture (or other sectors) is however largely constrained by a multitude of legal requirements. An important problematic point is the concentration in MTEs that is found in those wastes. Consequently, recovery of nutrients and MTEsmay be a key solution for optimal valorization of wastes. Many unit operations used in the field of chemical and biochemical engineering (mechanical operations on fluids, solids, mass and heat transfers, chemical reactions, etc.) could be used in order to achieve an efficient recovery yield of nutrients and trace elements. The aim of the BioRefine Project is to make an inventory of all recovery techniques of nutrients and MTEs in five countries: Belgium, France, Germany, United Kingdom and The Netherlands. Pilot plants will also be tested to assess the efficiency of new treatment techniques after which the most efficient processes will be chosen to be applied on a larger scale. In addition, the collected data will be used to propose exploitation scenarios taking into account legal constraints and optimized logistics.This work is supported through an INTERREG IVB NWE programme(ref. 320J-BIOREFINE). [less ▲]

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See detailA Single Envelope N-linked Glycosylation Site Defines Hyperpathogenicity of Bovine Leukemia Virus
De Brogniez, Alix ULg; Bouzar, Amel-Baya; Jacques, Jean-Rock ULg et al

Conference (2014, June 05)

Pathogens have co-evolved with their host to allow efficient replication and transmission without inducing excessive pathogenicity that would indirectly impair their persistence. This is exemplified by ... [more ▼]

Pathogens have co-evolved with their host to allow efficient replication and transmission without inducing excessive pathogenicity that would indirectly impair their persistence. This is exemplified by the bovine leukemia virus (BLV) model that induces lymphoproliferative disorders in ruminants only after extended latency periods of several years. In principle, the equilibrium reached between the virus and its host could be disrupted by emergence of more pathogenic strains. Intriguingly, this type of hyperpathogenic BLV strain could never been isolated in vivo nor designed in vitro. Using reverse genetics of an infectious molecular provirus, we have now identified a N-linked envelope glycosylation site that limits viral replication and pathogenicity. Onset of this particular mutation may thus represent a potential threat associated with emergence of hyperpathogenic BLV strains and possibly of new variants of the related primate T-lymphotropic viruses. [less ▲]

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See detailA PREFERENTIAL FOLDED CONFORMATION OF SOME BIS-(8-ISOPROPYL-ISOQUINOLINIUM) DERIVATIVES EXPLAINS STEREOSELECTIVE REDUCTION BY SODIUM BOROHYDRIDE
Dilly, Sébastien ULg; Badarau, Eduard; Dufour, Fabien et al

Poster (2014, June 05)

Small conductance Ca2+-activated K+ (SK) channels play a role in modulating the firing rate and the firing pattern of neurons [Waroux, Eur J Neurosci, 2005, 22, 3111]. A blockade of these targets could be ... [more ▼]

Small conductance Ca2+-activated K+ (SK) channels play a role in modulating the firing rate and the firing pattern of neurons [Waroux, Eur J Neurosci, 2005, 22, 3111]. A blockade of these targets could be useful for the treatment of cognitive dysfunction, neuronal hyperexcitability or dopamine related disorders [Liégeois, Curr Med Chem, 2003, 10, 625]. At the peripheral level, the inhibition of these channels was demonstrated to prevent and terminate atrial fibrillation [Diness, Circ Arrhythm Electrophysiol, 2010, 3, 380]. Moreover, SK channels might represent potential targets for a new class of anticancer agents due to their involvement in breast cancer cell migration [Potier, Mol Cancer Ther, 2006, 5, 2946]. So far, available blockers are not suitable CNS pharmacological tools being either peptides or small molecules with permanent positive charges [Liégeois, Curr Med Chem, 2003, 10, 625; Graulich, J Med Chem, 2007, 50, 5070; Badarau, Bioorg Med Chem Lett, 2011, 21, 6756]. Therefore, symmetrical bis-isoquinolinium compounds have subsequently been transformed to 1,2,3,4-tetrahydroisoquinoline analogues by using sodium borohydride leading to a diastereoisomeric mixture (figure 1) in order to obtain potential CNS-penetrating agents [Graulich, Bioorg Med Chem Lett, 2008, 18, 3440; Neny, Proceedings of the 12th International Conference on In Vivo Methods, Vancouver, Canada, 2008, 267; Koulchitsky, Acta Physiologica, 2009, 195, 670]. Resolution of these mixtures and characterization of the corresponding stereoisomers [Wouters, Eur J Med Chem, 2010, 45, 3240] are necessary before further biological evaluation. In a series of 8- isopropyl analogues, chiral resolution failed for the analogues with propyl and m-xylyl linkers since two and one peaks, respectively, were detected [Nistor, J Pharm Biomed Anal, 2013, 74, 273]. Could these results be explained by an ineffective resolution or would another phenomenon be involved? Further analysis using chiral chromatography, mass spectroscopy and circular dichroism of a sample of the propyl analogue revealed that it is a racemic mixture. X-ray cristallography and conformational analysis indicated a folded conformation of the propyl and m-xylyl analogues (figure 2) responsible for a stereoselective attack of the borohydride reagent during the reduction step. Additional 1H-NMR investigations support structural features detected by theoretical analysis. [less ▲]

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See detailApproche socio-écologique: arrangements de la complexité
Absil, Gaëtan ULg

Conference (2014, June 04)

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See detailLo stato di necessità, invenzione moderna o romana?
Gerkens, Jean-François ULg

Conference (2014, June 04)

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See detailL'épaule un carrefour complexe
WANG, François-Charles ULg; LOZZA, Alessandro

Conference (2014, June 04)

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See detailUn chiffre en débat. Controverse autour de la dette wallonne
Piron, Damien ULg

Conference (2014, June 03)

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See detailElectrical characterization of pGeSn/nGe diodes
Baert, Bruno ULg; Gupta, Somya; Gencarelli, Federica et al

Conference (2014, June 03)

I-V characteristics of pGeSn/nGe diodes have been measured and show very good properties. Simulations of the same structure are able to reproduce most of the observed behavior and point to the ... [more ▼]

I-V characteristics of pGeSn/nGe diodes have been measured and show very good properties. Simulations of the same structure are able to reproduce most of the observed behavior and point to the predominating influence of parameters such as the band gap energy of the GeSn layer. C-V characteristics showing little frequency dependence have also been measured, and their analysis for the determination of the carrier concentration is confirmed by simulations. More investigations, including the effect of temperature and other defects at the interface or in the bulk of either layers are still required in order to explain some of the observed behaviors, notably the reverse saturation current. [less ▲]

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See detailRelations between negative symptomatology and executive measures in schizophrenia.
Laloyaux, Julien ULg; Guettafi, Yassine; Dessart, Gregory et al

Poster (2014, June 03)

Introduction: Negative symptomatology and cognitive impairments are core features of persons diagnosed with schizophrenia that have a major negative impact on everyday life functioning. Further, some ... [more ▼]

Introduction: Negative symptomatology and cognitive impairments are core features of persons diagnosed with schizophrenia that have a major negative impact on everyday life functioning. Further, some authors (Konstantakopoulos et al., 2011) have suggested that negative symptoms and executive functions might represent different manifestations of the same syndrome, but this relation remains poorly understood. Objective: The objective was to explore relations between negative symptomatology (and in particular apathy) and executive functions in persons diagnosed with schizophrenia. Method: Twenty-seven individuals diagnosed with schizophrenia were evaluated with an extensive executive battery in addition to several measures of negative symptomatology (including specific measures of apathy) and real world functioning. Results: Results revealed that apathy was significantly related to measures of initiation (i.e. verbal fluency) and everyday life functioning. Moreover, more general measures of negative symptomatology were significantly related to multitasking abilities and cognitive flexibility. Discussion: In this study, we assessed the relations between negative symptomatology and executive measures. The results confirmed the links between these constructs, thus suggesting a common neural substrate. Conclusion: Based on results from the present study, executive dysfunctions and negative symptomatology may be seen as representing different manifestations of the same syndrome. [less ▲]

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See detailRay tracing enhancement for space thermal analysis: isocell method
Jacques, Lionel ULg; Masset, Luc ULg; Kerschen, Gaëtan ULg

in Sarler, Bozidar; Massaroti, Nicola; Nithiarasu, Perumal (Eds.) Third International Conference on Computational Methods for Thermal Problems (2014, June 02)

The finite element method (FEM) is widely used in mechanical engineering, especially for space structure design. However, FEM is not yet often used for thermal engineering of space structures where the ... [more ▼]

The finite element method (FEM) is widely used in mechanical engineering, especially for space structure design. However, FEM is not yet often used for thermal engineering of space structures where the lumped parameter method is still dominant. Radiative exchange factors (REFs) are usually computed through Monte Carlo ray-tracing. Due to the large number of elements composing a FE model, the computation of the REFs is prohibitively expensive. The developments of the new Isocell quasi-Monte Carlo ray tracing method are presented. The Isocell method enhances the uniformity of the generated quasi-random sequence of ray directions and leads to faster convergence. It is associated with different surface sampling to derive the REFs. The method is benchmarked against ESARAD, the standard ray-tracing engine for thermal analysis used in the European aerospace industry. Various geometries are used. In particular, one entrance baffle of the Extreme Ultraviolet Imager (EUI) instrument developed at the Centre Spatial de Liège in Belgium is used. The EUI instrument of the Solar Orbiter European Space Agency mission and will be launched in a Sun-centered 0.28 perihelion orbit in 2018. [less ▲]

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See detail« Quantification des politiques versus Démocratisation de la mesure : la gestion publique par les indicateurs à l’épreuve de la participation. les indicateurs sont-ils solubles dans la participation ?
Fallon, Catherine ULg

Conference (2014, June 02)

L'évaluation des politiques publiques contribue à la fois à l’efficacité de l'action publique et à sa légitimation, en déployant une double logique pour renforcer l’intelligibilité et l’acceptabilité de ... [more ▼]

L'évaluation des politiques publiques contribue à la fois à l’efficacité de l'action publique et à sa légitimation, en déployant une double logique pour renforcer l’intelligibilité et l’acceptabilité de la gestion publique. Cette démarche recourt de plus en plus souvent à des indicateurs de performances, sans questionner le caractère contingent et construit de leur émergence et le sacrifice de la complexité sociale qu'ils induisent. Une double dynamique est perceptible depuis quelques années dans ce domaine. Les pratiques et les discours autour de l’évaluation semblent osciller entre deux registres qui s’opposent sur de nombreux points : d’un côté le renforcement de cette logique managériale et de l’autre des exigences de nouvelles demandes participatives formulées par les groupes concernés par l’action publique. En termes managériaux, les réformes observées dans les modalités de des politiques publiques intègrent de nombreux principes du new public management sous différentes dénominations : démarches de « qualité », «mesure de performance », « culture du résultat »,.. Autant de concepts qui accompagnent la généralisation des dispositifs d’évaluation et de certification par les chiffres. Les exigences en matière de transparence et d’efficacité justifient un développement pléthorique d’indicateurs de performances (IP), car la mesure via un indicateur endosse aussi une fonction de légitimation (Zittoun 2009). En effet, le recours à des mesures de la performance est souvent justifié par une amélioration de l’action publique ainsi qu’à une plus grande « accountability » (Halachmi 2005; Van Thiel et Leeuw 2002) : par leur souci déclaré de transparence, elles semblent prolonger les impératifs de la démocratie et de ses exigences en matière de débats et d’information. D’autre part se multiplient des procédures délibératives qui associent citoyens et gouvernants pour « renforcer l’efficacité de l’action publique, en améliorant son contenu et en favorisant son acceptabilité sociale » (Chevallier 2011 : 227), contribuant au consensus social autour de l’action de l’état qu’elle légitime par ailleurs. « Le détour par l’écoute des citoyens se donne comme une figure obligée de l’action publique et comme un nouvel art de gouverner, comme si désormais il n’était plus possible de prendre de décision sans avoir consulté le public au préalable » (Blondiaux 2008 : 6), dynamique renforcée par l’extension actuelle des nouvelles technologies de l’information et de la communication et les nouveaux réseaux sociaux. Le NPM prône une pratique chiffrée s’appuyant sur une approche top-down, standardisée et uniformisante, basée sur un développement de connaissances statistiques construites à l’échelle du territoire d’intervention. A l’opposé, se dessine le détour vers une participation locale émanant d’une dynamique bottom-up, et proposant une approche localisée et complexe du territoire. Dans le cadre de l’évaluation des politiques publiques, ces deux registres sont en tension. Fraser et coll. ( 2006), résument bien les problèmes respectifs liés à ces deux approches. D’un côté, la question de la possibilité de généralisation de l’information à partir des données locales ; de l’autre le risque de « réduction » de ces données riches et contextualisées, que doivent formater et contrôler les experts en statistiques pour nourrir l’action publique. En effet, nous postulons que la quantification du social opère un double réductionnisme : premièrement un réductionnisme que nous pourrions qualifier de social, par la capacité du chiffre à réduire la complexité sociale à une seule donnée ; deuxièmement un réductionnisme normatif qui tend à faire basculer la focale de l’équité ou de la justice sociale vers la recherche de performance elle-même, celle-là même qui fait l’objet de la mesure et qui est transformée en objectif d’action pour les acteurs (Salais, 2010). Ogien (2009 :14) met en évidence le développement récent d’une science de la modélisation de l’action publique, « contribuant à la colonisation du raisonnement politique par les catégories de l’économie et du management ». Ce qui différencie les nouvelles approches d’évaluation, de qualité, et de mesures de performances de la dernière décennie, c’est la position des chiffres qui en viennent à structurer le processus décisionnel au lieu d’en être les simples auxiliaires (Dahler-Larsen 2012). La contestation de cette suprématie du chiffre est difficile, entre autre parce que les principes du NPM qui président à leur mise en œuvre semblent faire l’objet d’un large consensus et parce que les responsables politiques y trouvent des outils de communication mobilisant de façon particulièrement efficace les structures médiatiques de nos démocraties d’opinion. S’il y a « peu d’espace de résistance à la quantification » (Badet & Jany-Catrice 2010), c’est principalement lié à l’idée selon laquelle l’information sur un phénomène ne peut être que bénéfique à la prise de décision. Par leur potentiel de comparabilité, les chiffres relèguent au second plan les pratiques participatives qui ne peuvent se targuer d’un tel avantage. Pourtant, de nombreux auteurs critiques tendent à démontrer la normativité derrière l’information chiffrée, mettant à l’épreuve leur prétendue objectivité, leur caractère scientifique et leur neutralité. Barré (2010) parle d’un usage manipulatoire qui fait passer pour scientifique une construction en occultant le fait que cette construction est en cohérence avec la vision de ceux qui l’ont élaborée. La force du chiffre fait oublier le caractère conventionnel de son émergence (Desrosières 1993, 2008) : le chiffre « circule dans l’espace public indépendamment de son procédé de fabrication et « il échappe à son créateur pour vivre une vie autonome dans l’espace social » (Bureau 2010 :173) contribuant à peupler celui-ci d’une foule d’indicateurs, une machinerie pour classer et comparer échappant à toute emprise critique. Mais d’un autre côté, au niveau de la mise en œuvre des politiques, les acteurs de terrain cherchent à traduire les indicateurs choisis par des experts éloignés des « réalités » des communautés locales : ces concepts souvent ambigus définis au niveau global mobilisent généralement un nombre limité d’indicateurs synthétiques non représentatifs des problématiques locales : on peut observer cela pour le « développement durable » (Fraser et al. 2006) ou pour la « cohésion sociale » (Fallon et Feron 2013) . - Peut-on combiner ces deux approches ? Comment repenser les démarches participatives dans le cadre d’une sociologie de la quantification (bottom up) ? Les contributions proposent des analyses ciblées dans divers secteurs (cohésion, justice, budget, …) pour démontrer le potentiel politique du chiffre et poser deux lignes de questionnements. - Est il possible de définir des indicateurs de manière participative, en associant les stakeholders aux décisions concernant les conventions de mesures pour une traduction partagée de ce qui compte au niveau local ? De tels dispositifs définis de manière participative ont-ils leur place dans l’action publique ? - Quelle est le potentiel heuristique des démarches empiriques qui, rendant justice à la créativité et à la compétence des acteurs locaux, mettent en évidence des mécanismes locaux (de mise en résistance, ou de complaisance, ou d’autres) en réaction aux cadrages imposés ? Quelles stratégies mobilisent les professionnels du secteur appelés à intérioriser les normes gestionnaires pour échapper aux contraintes des données statistiques et pour mobiliser leur expertise contextuelle ? [less ▲]

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See detailComparison of Indicators to Evaluate the Resilience of Lab Scale Continuously Stirred Anaerobic Reactors Submitted to Biological Dysfunctions
Lemaigre, Sébastien; Adam, Gilles ULg; Goux, Xavier et al

Poster (2014, June 02)

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See detailSIMPLIFIED SEISMIC ANALYSIS OF LOCK GATES
Buldgen, Loïc ULg; Degée, Hervé ULg; Lesourne, Hervé et al

in PIANC 2014 Conference (2014, June 02)

The paper deals with the seismic design of lock gates. When such structures are submitted to an earthquake, the water contained in the chamber is responsible for an additional hydrodynamic pressure acting ... [more ▼]

The paper deals with the seismic design of lock gates. When such structures are submitted to an earthquake, the water contained in the chamber is responsible for an additional hydrodynamic pressure acting on the gate. This one is the sum of three different parts, respectively called the convective, rigid and flexible contributions. The two first ones have already been extensively studied in the literature, but the flexible part is more difficult to assess as it is largely influenced by the coupling occurring between the fluid and the gate. To overcome this difficulty, it is of course possible to use finite elements software, but doing so is not always convenient. This is why some research have been undertaken to provide a rapid way for approximating the flexible pressure on lock gates. This is achieved by applying the analytical approach that is shortly presented in this paper. As a matter of validation, the results obtained through this simplified procedure are compared to numerical solutions. The agreement between both of them is found to be satisfactory. [less ▲]

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See detailLes déterminants de la désinsertion professionnelle
Mairiaux, Philippe ULg

Conference (2014, June 02)

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See detailHOLOCENE DUST RECORD IN A BELGIAN PEAT BOG: MULTIPROXY GEOCHEMICAL APPROACH
Allan, Mohammed ULg; gael, le roux; Fagel, Nathalie ULg et al

Conference (2014, June 01)

Ombrotrophic peatlands are unique environmental archives of natural and anthropogenic atmospheric dust deposition. Their surface layers are exclusively fed by atmospheric inputs. A peat bog core from ... [more ▼]

Ombrotrophic peatlands are unique environmental archives of natural and anthropogenic atmospheric dust deposition. Their surface layers are exclusively fed by atmospheric inputs. A peat bog core from Misten in Eastern Belgium southern covering the last 7500 years (dated by 210Pb and 14C methods) was investigated to reconstruct dust depostion based on a combination of the Rare Earth Elements (REE) and lithogenic elements concentrations, as well as Nd and Pb isotopes data. Nd isotope signature was used to decipher between local and distal dust supplies, the Pb isotopes to trace the antropogenic influences. Peat humification was used to evaluate hydroclimatic conditions. Dust fluxes show pronounced increase at 3200-2800BC, 600BC, AD600, 1000AD, 1200AD and from 1700 AD. Lead isotope signatures are consistent with local and regional contamination by coal combustion and smelting activities. The Nd values show large variability, between -5 and –13, identifying three major sources of dust: local soils, distal volcanic and desert particles. Our results are in agreement with atmospheric reconstructions from other continental archives, confirming that the Misten peat is a valid archive for dust deposition. The approach combining geochemical elementary content and isotope data in ombrotrophic peat allows to decipher between dust flux changes related to human and climate forcing. [less ▲]

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See detailDe la matière à l'espace: une voie d'intégration numérique et matérielle
Delvaux, Frederic ULg; Bianchi, Romuald ULg; Jancart, Sylvie ULg

in Kubicki, Sylvain; Halin, Gilles; Bignon, Jean-CLaude (Eds.) Scan 14 séminaire de conception architecturale numérique : Interaction(s) des maquettes numériques (2014, June 01)

From a collaboration of formal and architectural research between architect and artist, we present the summary of an experimental approach that illustrates the creation and construction of a functional ... [more ▼]

From a collaboration of formal and architectural research between architect and artist, we present the summary of an experimental approach that illustrates the creation and construction of a functional space, located at the borders of the sculpture and the architecture. We present a look at the method, according to a revised approach to digital modeling / re-design. This has been an exploratory approach through the study of three generic models of the form. We present the experimental method, the selection of relevant parameters in form finding coupled with the integration of material and physical data specific to the object. We also expose the benefits of this approach, its limitations and the possibilities it offers as a generic point of view. [less ▲]

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See detailSynthesis of N-fluoroalkyl-tryptophan and study of their biological activity as potential substrates for indoleamine 2,3-dioxygenase
Henrottin, Jean ULg; Zervosen, Astrid ULg; Lemaire, Christian ULg et al

Poster (2014, June)

Indoleamine 2,3-dioxygenase (rhIDO) is an enzyme mainly expressed in brain and tumor cells and catalyzing the oxidative cleavage of the indole ring of L-tryptophan through the kynurenine pathway ... [more ▼]

Indoleamine 2,3-dioxygenase (rhIDO) is an enzyme mainly expressed in brain and tumor cells and catalyzing the oxidative cleavage of the indole ring of L-tryptophan through the kynurenine pathway. Furthermore this enzyme could be responsible for the eventual suppression of immune responses by blocking locally T-lymphocyte proliferation. The syntheses of 1-(2-fluoroethyl)-tryptophan (1-[19F]FETrp) and 1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)methyl)-tryptophan, two N-fluoroalkylated tryptophan derivatives, are described here. In vitro enzymatic assays with these two new potential substrates of rhIDO show that 1-[19F]FETrp is a good and specific substrate of hIDO. [less ▲]

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See detailAnalyse du métier de facilitateur et de son rôle dans la diffusion de normes d’emploi : le cas d’un bureau de chômage belge
Orianne, Jean-François ULg; Beuker, Laura ULg

Conference (2014, June)

En 2004, suite aux injonctions européennes en matière d’activation impulsées par les lignes directrices de 2003-2005, la Belgique met en place le PAC (ou Plan d’Accompagnement des chômeurs). Cette ... [more ▼]

En 2004, suite aux injonctions européennes en matière d’activation impulsées par les lignes directrices de 2003-2005, la Belgique met en place le PAC (ou Plan d’Accompagnement des chômeurs). Cette importante réforme prévoit – notamment – la mise en place de la procédure d’activation du comportement de recherche d’emploi par l’Office National de l’Emploi (Ou l’ONEm). Désormais, des agents sont spécifiquement dédiés à l’évaluation des efforts menés par les demandeurs d’emploi (ou DE) pour s’insérer sur le marché du travail : ce sont les facilitateurs. Si la procédure d’évaluation est officiellement définie, la décision, quant à elle, est bel et bien fonction de l’agent, qui doit interpréter le cadre réglementaire général à l’aune de la situation singulière du demandeur d’emploi. À l’aide d’une étude de cas réalisée au sein d’un bureau de chômage situé en Belgique francophone, nous allons tenter d’ouvrir la « boîte noire » du jugement des facilitateurs. À partir d’une approche qualitative cumulant des entretiens semi-directifs et de l’observation d’interactions entre facilitateurs et demandeurs d’emploi, nous montrerons que la décision des facilitateurs n’est ni arbitraire, ni déterminée. Elle est, au contraire, le fruit de la mobilisation d’une multitude d’appuis conventionnels dans l’action (Dodier, 1993). En outre, dans la lignée des travaux de Benarrosh (2000 ; 2006 ; 2012) nous démontrerons que ces agents sont des « pourvoyeurs » de normes institutionnelles précises à destination des demandeurs d’emploi. [less ▲]

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See detailCan we interpret linear kernel machine learning models using anatomically labelled regions?
Schrouff, Jessica ULg; Monteiro, Joao; Joao Rosa, Maria et al

Poster (2014, June)

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See detailGenetic diversity, structure and parentage analysis within several European apple germplasm collections assessed by microsatellite markers
Durel, Charles-Eric; Denancé, Caroline; Ravon, Elisa et al

Conference (2014, June)

Detailed reference viewed: 34 (1 ULg)
See detailRole of the progesterone receptor in the development of sexual behavior in female mice
Desroziers, Elodie ULg; Brock, Olivier; Baum, M.J. et al

Poster (2014, June)

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See detailStereoselective synthesis of peptidoglycan fragments on solid support
Simon, Justine ULg; Lamborelle, Nicolas ULg; Joris, Bernard ULg et al

Poster (2014, June)

The mammalian proteins, Nod1 and Nod2, are able to recognize peptidoglycan motifs during bacterial infection. Interestingly, Nod1 is a detector of peptides and muropeptides containing the meso-2,6 ... [more ▼]

The mammalian proteins, Nod1 and Nod2, are able to recognize peptidoglycan motifs during bacterial infection. Interestingly, Nod1 is a detector of peptides and muropeptides containing the meso-2,6-diaminopimelic acid (m-A2pm), a non-proteinogenic amino acid found in Gram- bacteria. In this work, we describe a synthesis of peptidoglycan motifs entirely on solid support. Solid-Phase Peptide Synthesis (SPPS), Cross Metathesis (CM) and sugar chemistry are three methods to anchor respectively amino acids, m-A2pm and sugars derivatives on a resin as solid support. [less ▲]

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See detailAnalysis versus synthesis for trending of gas-path measurement time series
Borguet, Sébastien ULg; Léonard, Olivier ULg; Dewallef, Pierre ULg

in Proceedings of ASME Turbo Expo 2014 (2014, June)

Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear ... [more ▼]

Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear filters such as the exponentially weighted moving average filter are traditionally used for noise removal. Unfortunately, these low-pass filters distort trend shifts indicative of faults, which increases the detection delay. The present paper investigates two new approaches to non-linear filtering of time series. On one hand, the synthesis approach reconstructs the signal as a combination of elementary signals chosen from a pre-defined library. On the other hand, the analysis approach imposes a constraint on the shape of the signal (e.g., piecewise constant). Both approaches incorporate prior information about the signal in a different way, but they lead to trend filters that are very capable at noise removal while preserving at the same time sharp edges in the signal. This is highlighted through the comparison with a classical linear filter on a batch of synthetic data representative of typical engine fault profiles. [less ▲]

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See detailSimple connectome inference from partial correlation statistics in calcium imaging
Sutera, Antonio ULg; Joly, Arnaud ULg; François-Lavet, Vincent ULg et al

in Proceedings of Connectomics 2014 (ECML 2014) (2014, June)

In this work, we propose a simple yet effective solution to the problem of connectome inference in calcium imaging data. The proposed algorithm consists of two steps. First, processing the raw signals to ... [more ▼]

In this work, we propose a simple yet effective solution to the problem of connectome inference in calcium imaging data. The proposed algorithm consists of two steps. First, processing the raw signals to detect neural peak activities. Second, inferring the degree of association between neurons from partial correlation statistics. This paper summarises the methodology that led us to win the Connectomics Challenge, proposes a simplified version of our method, and finally compares our results with respect to other inference methods. [less ▲]

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See detailL’effet des dispositifs d’intermédiation sur les trajectoires professionnelles des travailleurs. Le cas d’un bureau de recrutement, recherche et sélection de personnel.
Gérard, Julie ULg

Conference (2014, June)

Au cours de ces dernières années, le souci d’allier flexibilité et sécurité au travail a conduit à l’essor considérable des métiers de l’intermédiation (Orianne et Maroy, 2008). En particulier dans le ... [more ▼]

Au cours de ces dernières années, le souci d’allier flexibilité et sécurité au travail a conduit à l’essor considérable des métiers de l’intermédiation (Orianne et Maroy, 2008). En particulier dans le domaine de l’accompagnement et du développement de carrière, divers dispositifs privés d’aide et de suivi ont vu le jour afin de contribuer à l’amélioration des conditions de travail et d’assister les travailleurs dans leurs transitions professionnelles. Par leur action, ces nouveaux dispositifs n’hésitent pas à complexifier les temporalités sociales en créant de nouvelles opportunités d’emploi et en redéfinissant les rythmes de carrière. À l’aide d’une étude de cas dans le secteur du recrutement belge, nous analyserons la capacité d’un processus de mise en emploi à remplir de tels objectifs dans un contexte de gestion mixte du marché du travail. Approchée d’une manière qualitative (entretiens semi-directifs et observations), nous étudierons l’apport de cette agence de placement au travers d’un cadre théorique qui intègre les concepts de dispositif (Foucault, 1977 ; Peeters et Charlier, 1999 ; Raffnsoe, 2008) et de réseaux sociaux (Grossetti 2005, 2008 et 2011). Nous montrerons qu’un plus de régir l’offre et la demande de travail, ce dispositif d’intermédiation, par son système de cooptation et son accompagnement de carrière, assure la fluidification du marché et sécurise la dynamique des transitions professionnelles. [less ▲]

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See detailMembrane interactions of cyclic lipodepsipeptides from the viscosin group
Geudens, Niels; Feher, Krisztina; De Vleeschouwer et al

Poster (2014, June)

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See detailThe role of segmentation and investor recognition through the lens of cross‐listing activity
Mouchette, Xavier ULg; Muller, Aline ULg; Carrieri, Francesca

Conference (2014, June)

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See detailEstudio ante y postmortem de las caracteristicas fisiopatologicas del tracto genital y sus factores de riesgo en vacas lecheras en el sur de Vietnam
Nguyen, Kien Cuong; Tomas Mulet, Cristina; Okouyi-Mfoumou, Marcel et al

Conference (2014, June)

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See detailProduction, Private Economy and State Entanglement in Early Northern Mesopotamia
Mas, Juliette ULg

Conference (2014, June)

Ancient economic systems from Southern and Central Mesopotamia are quite well known when Northern Mesopotamia ones remain less known from this point of view. If we already know that, during Bronze Age ... [more ▼]

Ancient economic systems from Southern and Central Mesopotamia are quite well known when Northern Mesopotamia ones remain less known from this point of view. If we already know that, during Bronze Age, households played a deciding role in several kinds of production, their degree of dependence or independence to the State still has to be cleared. The archaeological data clearly show that private workshops, set up in private houses, could be very efficient and specialized. Furthermore, these economic entities could be assimilated to private enterprises, which were able to handle their own administrative duties. On the other hand, we know from the texts that the Palace and the temples were also a main element of ancient economic systems. If public administrations should, in some cases, have supplied raw materials, hired workforce, and dealt with the distribution of produced goods, it seems that the production didn’t take place in the palace itself. Dealing both with archaeological and textual data, could help to better define the role and the importance of both public and private components in early Mesopotamian economic systems. [less ▲]

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See detailOn the Quality of BGP Route Collectors for iBGP Policy Inference
Cittadini, Luca; Vissicchio, Stefano; Donnet, Benoît ULg

in IFIP Networking (2014, June)

A significant portion of what is known about Internet routing stems out from public BGP datasets. For this reason, numerous research efforts were devoted to (i) assessing the (in)completeness of the ... [more ▼]

A significant portion of what is known about Internet routing stems out from public BGP datasets. For this reason, numerous research efforts were devoted to (i) assessing the (in)completeness of the datasets, (ii) identifying biases in the dataset, and (iii) augmenting data quality by optimally placing new collectors. However, those studies focused on techniques to extract information about the AS-level Internet topology. In this paper, we show that considering different metrics influences the conclusions about biases and collector placement. Namely, we compare AS-level topology discovery with \iac inference. We find that the same datasets exhibit significantly diverse biases for these two metrics. For example, the sensitivity to the number and position of collectors is noticeably different. Moreover, for both metrics, the marginal utility of adding a new collector is strongly localized with respect to the proximity of the collector. Our results suggest that the ``optimal'' position for new collectors can only be defined with respect to a specific metric, hence posing a fundamental trade-off for maximizing the utility of extensions to the BGP data collection infrastructure. [less ▲]

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See detailEffect of plant defence elicitor on aphid and disease cross infestations
Bosquée, Emilie ULg; Oumarou, Saadatou; Qiu, Dewen et al

Poster (2014, June)

Various bio-aggressors can infest potato plants (Solanum tuberosum L.) throughout its life cycle. In addition to aphids, in particular Myzus persicae Sulzer which transmits Potato virus Y (PVY), plant ... [more ▼]

Various bio-aggressors can infest potato plants (Solanum tuberosum L.) throughout its life cycle. In addition to aphids, in particular Myzus persicae Sulzer which transmits Potato virus Y (PVY), plant pathogenic fungus such as Botrytis cinerea are able to cause damage. To determine the interactions between various bio-aggressors on potato plant defence mechanisms, (1) the effect of an attack by M. persicae followed by an attack by B. cinerea and vice versa, as well as (2) the effect of an elicitor on biological parameters of M. persicae and development of B. cinerea were assessed. On the other hand, (3) the effect of Botrytis cinerea and an elicitor on the efficiency of transmission of PVY by M. persicae was examined. The previous infection by B. cinerea resulted in a significant decrease in growth rate and a sharp reduction of M. persicae fertility, while the infection level of B. cinerea followed by M. persicae infestation was non-significant. Despite a reduction in growth and fertility of M. persicae during the first days of observation, the effect of elicitor on the biological parameters of M. persicae as well as on the development of B. cinerea was non-significant. Regarding the investigations on the PVY transmission by M. persicae, when the elicitor or Botrytis is previously applied on the plant, a significant reduction in the rate of transmission was observed. [less ▲]

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See detailMODEL PREDICTIVE CONTROL OF CONGESTION AND VOLTAGE PROBLEMS IN ACTIVE DISTRIBUTION NETWORKS
Soleimani Bidgoli, Hamid ULg; Glavic, Mevludin ULg; Van Cutsem, Thierry ULg

in Proc. of CIRED Workshop 2014 (2014, June)

This paper presents a centralized control scheme, inspired of Model Predictive Control (MPC), to manage thermal overloads and correct abnormal voltages in real-time. The control scheme is able to smoothly ... [more ▼]

This paper presents a centralized control scheme, inspired of Model Predictive Control (MPC), to manage thermal overloads and correct abnormal voltages in real-time. The control scheme is able to smoothly bring the system within the desired limits, taking into account its near-future evolution. The control method effectiveness is illustrated on a 20-kV, 32-bus network hosting four distributed generation units. [less ▲]

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See detailThe role of segmentation and investor recognition through the lens of cross-listing activity
Mouchette, Xavier ULg; Carrieri, Francesca; Muller, Aline ULg

Conference (2014, June)

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See detailDouble Sweep Preconditioners for propagation problems solved by Optimized Schwarz Methods
Vion, Alexandre ULg; Geuzaine, Christophe ULg

in Proceedings of the 6th International Conference on Advanced COmputational Methods in ENgineering, ACOMEN 2014 (2014, June)

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See detailCrime Hotspots In Belgium: Spatial He terogeneity In The Multivariate Regression Model?
Trotta, Marie ULg

Conference (2014, June)

Place attractiveness is an important property to consider when modelling the spatial behaviour of a serial offender. Small spatial units are privileged in the recent literature to study the crime ... [more ▼]

Place attractiveness is an important property to consider when modelling the spatial behaviour of a serial offender. Small spatial units are privileged in the recent literature to study the crime concentration-urban backcloth relationship, with the drawback of focusing on a single city. However, the urban backcloth is also shaped by the inter-cities and city-hinterland relationships. Our objective is to model the concentration of sexual offences for entire Belgium, at the very precise scale of the statistical sector in order to take into account the role of the urban hierarchy. Methods: We analyse the ViCLAS data for Belgium between 2004 and 2011. Specifically, we study the relationship between the concentration of initial contact scenes and socio-economic characteristics and facilities of the statistical sector, using two spatial models. First, we computed a spatial lag zero-inflated model (ZINB) in order to evaluate the global predictive capacities of the model. Then, a Poisson geographically-weighted regression (GWR) was run to study the spatial heterogeneity for each of the explanatory variables. Results: The zero-inflated negative binomial model with spatial lag recovers the neighbourhood environmental quality, the concentration of economic and cultural activities, and drinking places as major significant factors (Mc Fadden’s pseudo-r² of 0.2). The Poisson geographically-weighted regression underestimates the crime concentrations but highlights the spatial heterogeneity [less ▲]

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See detailInhibitors of glycosylhydrolases as potential insecticides : focus on aphid model
Bosquée, Emilie ULg; Vandermoten, Sophie; Richel, Aurore ULg et al

Poster (2014, June)

Beside conventional neurotoxic compounds, new kinds of insecticides are investigated and new specific targets are in current research. According to the energy metabolic pathway, several enzymes are ... [more ▼]

Beside conventional neurotoxic compounds, new kinds of insecticides are investigated and new specific targets are in current research. According to the energy metabolic pathway, several enzymes are interesting to bring potential specific control of arthropods. Indeed, glycosylhydrolase group is very diversified from glucanases to trehalases, until chitinases. Different kinds of inhibitors were here tested to determine their potential role as new targetted aphicides. After different assays using the selected inhibitors in artificial diets, the most efficient molecules at 50-100 μg ml-1were kept for further proteomic tasks. The proteome patterns of aphids related to different inhibitor treatments were determined by two dimension electrophoresis, 2D-Differencial In Gel Expression (2D-Dige) coupled with mass spectrometry (ESI-MS-MS and Maldi-Tof-MS-MS) and data bank investigations. Particular proteins of interest were selected and accurately characterised with both fundamental but also applied views. Not only the carbohydrate metabolic pathway was disturbed with the use of glycosylhydolases inhibitors, other primary functions were also modified (amino acid synthesis, stress response, etc). This proteomic approach was discussed as an interesting and reliable tool to study the biologically involved proteins from aphids in response to specific tested enzymatic inhibitors with further ideas to be promoted as new insecticides to control insect pests. [less ▲]

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See detailUsing intensive multiyear fish-pass monitoring to analyse seasonal upstream movement patterns of patrimonial holobiotic potomadromous fish species in a medium size river
Benitez, Jean-Philippe ULg; Nzau Matondo, Billy ULg; Dierckx, Arnaud ULg et al

in Proceedings of the 10th International Conference on Ecohydraulics (2014, June)

Belgian rivers are fragmented by numerous obstacles which considerably limit the free access of fish to functional habitats. Fish-passes are major tools used to increase stream continuity and improve ... [more ▼]

Belgian rivers are fragmented by numerous obstacles which considerably limit the free access of fish to functional habitats. Fish-passes are major tools used to increase stream continuity and improve connectivity in the upstream direction. Using two modern multispecies fish-passes, this study aims to investigate multiyear abundance of holobiotic potamodromous fish and their seasonal movement patterns in relation with environmental factors. The fish passes were monitored continuously during 5 and 7 years and are located in two Belgian streams: the (19.3m³.s-1) and the Berwinne (1.9m³.s-1). Results revealed the presence of 20 different fish species, 14 species in the Berwinne and 19 species in the occurrence, salmonids and cyprinids species were predominant. A great interspecific and intraspecific variability in capture periodicity and in terms of stimulation by combination of factor environmental was observed. This study highlights the complexity and the omnipresence of holobiotic potamodromous fish movements at different life stages, in medium size river and brings new information on fish passes efficiency and use by these poorly known species. [less ▲]

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See detailL’effet d’un dispositif public d’accompagnement et de formation belge sur les trajectoires professionnelles des demandeurs d’emploi
Gérard, Julie ULg

Conference (2014, June)

: Suite aux récents bouleversements économiques et sociaux touchant les pays de l’Union Européenne, de nombreux partenariats entre services publics d’emploi et agences d’emploi privées se sont développés ... [more ▼]

: Suite aux récents bouleversements économiques et sociaux touchant les pays de l’Union Européenne, de nombreux partenariats entre services publics d’emploi et agences d’emploi privées se sont développés et complexifiés, suivant une logique de gestion mixte du marché de l’emploi. Cette communication porte sur l’étude d’un partenariat public-privé entre un service public régional belge et un organisme de formation. À partir des apports conceptuels et théoriques de la sociologie de l’action publique et de la littérature propre aux agences d’emploi privées et aux partenariats public-privé, nous analyserons la capacité d’un dispositif public à assurer la remise à l’emploi de son public-cible. Pour ce faire, nous étudierons son rôle et ses effets sur les trajectoires professionnelles des demandeurs d’emploi y recourant. [less ▲]

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See detailSorting of crop residues and fossil bones from soil by NIR Hyperspectral Imaging
Vincke, Damien; Eylenbosch, Damien ULg; Baeten, Vincent et al

Poster (2014, June)

Soil is a complex matrix containing a wide variety of constituents of interest for disciplines like agronomy or archaeology; it could either be crop residues like roots and straws or bones and ceramics ... [more ▼]

Soil is a complex matrix containing a wide variety of constituents of interest for disciplines like agronomy or archaeology; it could either be crop residues like roots and straws or bones and ceramics. Current challenges comprise the detection of these constituents as well as the assessment of their qualitative parameters by means of fast and non-destructive analytical methods. The scope of this work is to present two applications using Near Infrared Hyperspectral Imaging (NIR-HSI) combined with chemometrics to sort constituents of soil and to assess their qualitative parameters. The first application concerns the feasibility study of using NIR-HSI to sort crop residues such as roots and straws in soil. The second application aim to develop a method to assess the level of collagen preservation in fossil bones. [less ▲]

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See detailInvestigation of differential virus transmission efficiency in aphid strains: from biological to proteomic assays
Bosquée, Emilie ULg; Francis, Frédéric ULg

Poster (2014, June)

Aphids are well known for their variable efficiency in virus transmission to host plant. Not only aphid species but also aphid strain is an important factor to consider in the plant-aphid-virus ... [more ▼]

Aphids are well known for their variable efficiency in virus transmission to host plant. Not only aphid species but also aphid strain is an important factor to consider in the plant-aphid-virus interactions. In order to investigate these relations, different approaches should be developped from biological observations assessing the virus transmission efficiency to molecular tasks to better know the involved mechanisms in the aphid vector. After a period of virus acquisition on an artificial diet (depending on the kind of transmission, permanent or non permanent ways), the virus transmission rate were assayed and followed by the determination of the presence of virus in the aphid by PCR or immudetection. The aphids were then collected to investigate the variation of aphid proteome and potential involvement in virus interactions. Changes in protein expressions were investigated using a 2D-DIGE approach comparing most and least efficient aphid strains selecting different aphid – virus models (PVY and PLRV in potato, BYDV in wheat, CMV on tobacco) . The proteome changes were analysed using the samespot software. Protein spots with significant up- and down expressions were then mechanically picked, trypsin digested and analysed by Maldi-Tof-Tof. Significantly changed proteins were classify according to metablic pathways and biological functions. Interesting proteins found to probably interact with virus were not only detected from aphid but also from related bacterial symbionts. Theses results were discussed in order to better understand virus – vector relations and potentially promote new ways to control virus transmitted by hemipteran pest. [less ▲]

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See detailFlanders Ahead… Wallonia Behind (But Catching Up). Reconstructing Communities through Science, Technology, and Innovation Policymaking
Charlier, Nathan ULg; Van Oudheusden, Michiel ULg

Conference (2014, June)

Abstract Drawing on a documentary analysis of two socio-economic policy programs, one Flemish (“Vlaanderen In Actie”; VIA), the other Walloon (“Marshall Plans”; MPs), and a discourse analysis of how these ... [more ▼]

Abstract Drawing on a documentary analysis of two socio-economic policy programs, one Flemish (“Vlaanderen In Actie”; VIA), the other Walloon (“Marshall Plans”; MPs), and a discourse analysis of how these programs are received in one Flemish and one Francophone quality newspaper, this paper illustrates how Flanders and Wallonia both seek to become top-performing knowledge-based economies (KBEs). The paper discerns a number of discursive repertoires, such as “Catching up,” which Flemish and Walloon policy actors draw on to legitimize or question the transformation of Flanders and Wallonia into KBEs. The “Catching up” repertoire places Flanders resolutely ahead of Wallonia in the global race towards knowledge, excellence, and science-driven innovation, but suggests that Wallonia may, in due course overtake Flanders as a top-competitive region. Given the expectations and/or fears that “Catching up” evokes among Flemish and Walloon policy actors, the repertoire serves these actors as a flexible discursive resource to make sense of, and shape, their collective futures, and thus their identities. By rendering explicit how Flanders and Wallonia each acquire a distinct identity through the global KBE, the paper underlines the simultaneity of, and the interplay between, globalizing forces and particularizing tendencies and illuminates the political, nation-building and identity-building functions of science, technology, and innovation. The paper starts from the following preliminary observations. While both the VIA plan and the MPs emphasize the need of transforming Flanders and Wallonia into KBEs in order meet the demands of globalization (OECD 1996), the plans adopt a different tone and stance. The Flemish plan repeatedly states the need of transforming Flanders into “a top region, not only in Europe, but in the world, particularly in the social and economic field” (VIA, 2006: 4). It also states that Flanders is already prosperous and already has many strengths, but that the welfare and prosperity of Flanders are “under threat” in a “challenging global economic environment” (2). The message is thus that Flanders is doing relatively well in the global economy, but that it must do even better if it is to maintain its competitive edge and its welfare. By contrast, the MP is framed from the perspective of Walloon recovery and “redressement.” Although the term “Marshall Plan” evidently brings to mind the European Recovery Program for rebuilding Western Europe after World War II, recovery also refers to the period of prosperity before the World Wars, when Wallonia was one of the most economically advanced industrial regions in Europe. The MP suggests that Wallonia’s glorious past (“le passé glorieux”) can be rewon, if the Walloons deploy every tool they can muster and work together to “relaunch” the Walloon economy (3). To incite joint action, the MP urges the Walloons to become the architects of their own fate. This aspiration is clearly expressed in the opening sentence of the first MP plan: “The federalization [of Belgium; by which is meant the regionalization of policy and competences] bestows the Walloons with political autonomy, which renders them responsible for their own destiny.” At the same time, this statement reads as a call to independence, as the Walloons are bestowed with political autonomy (by the Flemings, who have repeatedly pushed for the dismantling of Belgium as a unitary state). As the above excerpts from the Flemish and Walloon policy plans indicate, VIA and the MPs characterize a state of political and economic affairs, take position in relation to these affairs, and, most importantly, envision a prosperous future for the Flemish and Walloon region, respectively. The plans are thus driven by expectations, visions and values, as well as fears. They mobilize arguments, explanations, evaluations, descriptions and prescriptions, sometimes by drawing on tropes or stereotypes, anecdotes, and illustrations. As the plans also indicate, transforming Flanders and Wallonia into top KBE regions does not happen by itself. For instance, while the VIA plan describes Flemings as entrepreneurs, it also states that “we must dare to be entrepreneurial” (3). Similary, the MP urges Walloon citizens to change their “état d’esprit” or mindset, if economic growth is to ensue (3). Thus, identity construction and transformation are in order both in Flanders and in Wallonia. The above observations serve as starting points for our media analysis. As we want to know whether, and how, these particular conceptions of the nation/region are picked up in press reporting on STI policies, we ask the following interrelated questions: How are the Flemish (VIA) and Walloon STI policies (MPs) received in the Flemish and Francophone press? Do we discern in the press the same notions of identity as in the policy programs? Are these notions reproduced, problematized or transformed? If so, in what ways? What does this mean for Flemish and Walloon identity construction, and for the construction of “Belgium” at large? Recognizing the role of “institutions of power” (e.g. language, media, technologies) in articulating nationalism (Anderson 1991: 163; Billig 1995: 11), our analysis conceives of journalists and the press as potential policy agenda setters and opinion makers, as the press potentially reproduces and redefines political identities. As this paper will illustrate, the Flemish and Francophone press speak out on issues of collective identity and also offer various policymakers a platform to express their views on regional economic development, STI, and the state. Thus, from our perspective, policymaking is not only the prerogative of mandated policymakers, but of journalists and other opinion leaders (e.g. captains of industry) as well (Lenschow & Sprungk 2010). To enable analysis, we draw on a range of literatures, including science and technology studies, discourse analysis, and media analyses. Our approach is interpretive and interactionist, as it assumes that realities (e.g. identities, nations, as well as practices and materialities) are socially constructed rather than exist as objective phenomenon that can be discovered through empirical testing (Fischer 2003: 118). Hence, we ask how identity is created, structured, maintained, or conversely deconstructed, resisted, and challenged. Our aim is thus not to uncover an objective reality behind identity, but to understand how identities are collectively made and remade on a continuous basis. To this end, we draw on the notion of “coproduction” (Jasanoff 2006: 2) to empirically demonstrate how STI and nationalism are “coproduced” through technoscientific practices (Felt 2013). In what follows, we first present, discuss, and situate Flemish and Walloon STI policies in time and place, as a means of contextualizing the “nationalisms” inscribed in the VIA plan and MPs. Next, we present our methodological framework for discourse and media analysis, our data, and key findings. Upon drawing together these findings, we single out the storyline of “Catching up” as an important discursive backdrop against which processes of collective identity construction play out through STI policymaking and press reporting. We conclude by tying our findings into a broader discussion about the place of Belgium in Europe and the world, as nation states are constantly (re)defined in terms of their constituent segments and overarching structures, including the KBE. The paper’s topics resonate with the overall conference theme and specifically tie into the following conference strands: • Policy emergence, implementation, diffusion and transfer • National science policies and the global scientific enterprise • The multi-level governance of research and innovation and the challenge of co-ordination Keywords: Flanders, Identity, Knowledge-based economy, Science and technology policy, Wallonia. References Anderson, B. (1991), Imagined Communities. Reflection on the Origin and Spread of Nationalism. London, Verso. Billig, M. (1995), Banal Nationalism. London, Sage. Felt, U. (2013), “Keeping Technologies Out: Sociotechnical imaginaries and the formation of a national technopolitical identity,” Pre-print; Published by the Department of Social Studies of Science, University of Vienna, February 2013; http://sciencestudies.univie.ac.at/publications Fischer, F. (2003), Reframing Public Policy. Discursive Politics and Deliberative Practices. Oxford, UK, Oxford University Press. Flanders in Action (VIA); www.vlaandereninactie.be Jasanoff, S. 2006. The idiom of co-production. In: Jasanoff, S., Ed., States of Knowledge. The Coproduction of Science and Social Order. New York, Routledge, 1-12. Lenschow, A. & Sprungk, C. (2010), “The Myth of a Green Europe,” Journal of Common Market Studies, 48(1), 133-154. OECD (1996), The Knowledge Based Economy, OECD/GD, (96)102. Plan Marshall (MP); http://www.wallonie.be/fr/actualites/plan-marshall-2022 [less ▲]

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See detailINVESTIGATION OF TWO IMPROVED TRADITIONAL MEDICINES: DEVELOPMENT AND VALIDATION OF A LC-UV METHOD FOR THE DOSAGE OF A TRACER COMPOUND
Tshisekedi Tshibangu, Pascal; Kalenda Dibungi, Pascal; Rozet, Eric ULg et al

Poster (2014, June)

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See detailDistributed Model-free Control of Photovoltaic Units for Mitigating Overvoltages in Low-Voltage Networks
Aristidou, Petros ULg; Olivier, Frédéric ULg; Hervas, Maria Emilia et al

in Proc. of CIRED 2014 workshop (2014, June)

In this paper, a distributed model-free control scheme to mitigate overvoltage problems caused by high photovoltaic generation in low-voltage feeders is proposed. The distributed controllers are ... [more ▼]

In this paper, a distributed model-free control scheme to mitigate overvoltage problems caused by high photovoltaic generation in low-voltage feeders is proposed. The distributed controllers are implemented on the photovoltaic inverters and modulate the active and reactive power injected into the network. In particular, they direct photovoltaic units first to consume reactive power and, if necessary, curtail active power generation to reduce high voltages in the feeder. [less ▲]

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See detailFigures du critique-écrivain, formes et pratiques du discours métalittéraire: Introduction et conclusions
Stienon, Valérie ULg; Van Nuijs, Laurence

Conference (2014, June)

Du XIXe siècle à nos jours, de nombreux écrivains ont combiné écriture de création et critique littéraire. À ces pratiques mêlées correspondent des statuts hybrides, dont celui de « critique-écrivain » ... [more ▼]

Du XIXe siècle à nos jours, de nombreux écrivains ont combiné écriture de création et critique littéraire. À ces pratiques mêlées correspondent des statuts hybrides, dont celui de « critique-écrivain » est peut-être le plus représentatif. Ce colloque se propose d’interroger cette figure bifide, en prenant en considération les divers paramètres de la critique littéraire en tant que pratique protéiforme, depuis l’institutionnalisation de la critique au XIXe siècle (critique journalistique, critique des écrivains et critique universitaire) jusqu’à la diversification moderne des types de discours critique (théorique, historique, médiatique, essayiste, romanesque). Comment les rapports entre critique et création sont-ils imaginés, confirmés voire inversés par les écrivains ? Par rapport à quels modèles et repoussoirs les écrivains se définissent-ils en critiques ou en créateurs (ceux, par exemple, du théoricien, de l’essayiste, du chroniqueur, du sociologue ou encore du polémiste) ? Pourquoi la postérité a-t-elle retenu comme critiques des auteurs qui ont par ailleurs investi ou approché une production spécifiquement littéraire ? Et comment ces rapports se renégocient-ils tout au long de l’histoire de la critique ? [less ▲]

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See detailETEROGENEITÀ GENETICA DI NOROVIRUS BOVINI IDENTIFICATI IN ITALIA
Di Felice, Eliabetta; Di Profio, Federica; Melegari, Irene et al

Poster (2014, June)

I norovirus (NoV) sono piccoli virus a RNA monocatenario appartenenti alla famiglia Caliciviridae. Sulla base dell’analisi di sequenza del gene ORF2 codificante per la proteina capsidica VP1, i NoV sono ... [more ▼]

I norovirus (NoV) sono piccoli virus a RNA monocatenario appartenenti alla famiglia Caliciviridae. Sulla base dell’analisi di sequenza del gene ORF2 codificante per la proteina capsidica VP1, i NoV sono attualmente classificati in sei genogruppi (G), con GI, GII e GIV responsabili di gastroenterite nell’uomo. Calicivirus enterici morfologicamente simili a NoV umani sono stati identificati per la prima volta in vitelli diarroici nel Regno Unito nel 1978 e in Germania nel 1980. Il sequenziamento nucleotidico dell’intero genoma ha permesso di classificare i NoV bovini (BoNoV) all’interno del genogruppo III in due genotipi, GIII.1 (prototipo Bo/Jena/80/DE) e GIII.2 (prototipo Bo/Newbury/76/UK). I BoNoV hanno una diffusione mondiale con una maggiore prevalenza di virus GIII.2-like. Tuttavia, studi recenti basati sull’analisi nucleotidica a livello della giunzione fra la polimerasi (RdRp) ed il capside, hanno dimostrato la circolazione di ceppi ricombinanti. Nel presente lavoro vengono riportati i risultati di un’indagine per la ricerca e tipizzazione di BoNoV condotta su quattro allevamenti bovini ubicati nelle province di Teramo e Pescara. A tal fine, 104 tamponi rettali collezionati da vitelli asintomatici sono stati sottoposti a nested RT-PCR impiegando due set di primer specifici per BoNoV in grado di amplificare un frammento di 326 bp della RdRp. L’RNA di BoNoV è stato identificato nel 10,5% (11/104) degli animali testati. L'analisi di sequenza ha evidenziato per nove sequenze un’elevata identità nucleotidica (nt) (88-96%) con i ceppi GIII.2-like, mentre per due è stata rilevata la maggiore identità (87-90% nt) con i BoNoV GIII.1-like. Per sette ceppi è stata ottenuta anche una sequenza di circa 750 bp che includeva oltre che la regione parziale della RdRp, la regione 5’ capsidica. Sulla base dell’analisi molecolare, cinque ceppi sono risultati strettamente correlati con BoNoV GIII.2-like, mentre solo uno dei due ceppi con polimerasi GIII.1-like, ha mostrato la maggiore identità nucleotidica nei confronti di BoNoV appartenenti al genotipo 1. Il ceppo 80/TE/IT che possedeva una polimerasi GIII.1-like, a livello capsidico ha mostrato la più alta identità con ceppi GIII.2-like, suggerendo un fenomeno di ricombinazione a livello della giunzione ORF1/ORF2. [less ▲]

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See detailPrediction of macroscopic mechanical properties of a polycrystalline microbeam subjected to material uncertainties
Lucas, Vincent ULg; Wu, Ling ULg; Arnst, Maarten ULg et al

in Cunha, Álvaro; Caetano, Elsa; Ribeiro, Pedro (Eds.) et al Proceedings of the 9th International Conference on Structural Dynamics, EURODYN 2014 (2014, June)

The first resonance frequency is a key performance characteristic of MEMS vibrometers. In batch fabrication, this first resonance frequency can exhibit scatter owing to various sources of manufacturing ... [more ▼]

The first resonance frequency is a key performance characteristic of MEMS vibrometers. In batch fabrication, this first resonance frequency can exhibit scatter owing to various sources of manufacturing variability involved in the fabrication process. The aim of this work is to develop a stochastic multiscale model for predicting the first resonance frequency of MEMS microbeams constituted of polycrystals while accounting for the uncertainties in the microstructure due to the grain orientations. At the finest scale, we model the microstructure of polycrystaline materials using a random Voronoï tessellation, each grain being assigned a random orientation. Then, we apply a computational homogenization procedure on statistical volume elements to obtain a stochastic characterization of the elasticity tensor at the second scale of interest, the meso-scale. In the future, using a stochastic finite element method, we will propagate these meso-scale uncertainties to the first resonance frequency at the coarser scale. [less ▲]

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See detailRole of estradiol in the feminization of lordosis behavior in female mice
Trouillet, Anne-Charlotte ULg

Poster (2014, June)

The classic theory of mammalian brain and behavioral sexual differentiation holds that an organizational action of testosterone, secreted perinatally by the male’s testes, controls male-typical aspects of ... [more ▼]

The classic theory of mammalian brain and behavioral sexual differentiation holds that an organizational action of testosterone, secreted perinatally by the male’s testes, controls male-typical aspects of brain and behavioral development, whereas no active perinatal sex hormone signaling is required for female-typical differentiation. However, it has recently been shown using aromatase knock out (ArKO) mice, which are deprived of estradiol due to a targeted mutation in the aromatase gene, that estradiol may also actively contribute to the differentiation of female-typical aspects of behavior over a specific pre-pubertal period. Female ArKO mice showed significantly lower levels of lordosis behavior than wild type controls following adult ovariectomy and treatment with ovarian hormones. This deficit was restored by treating female ArKO mice with estradiol benzoate between postnatal days 15 and 25. However, the mechanism by which estradiol acts prepubertally in female mice to feminize lordosis behavior remains to be elucidated. Therefore, in a first attempt, we are determining which neuropeptides are in particularly sensitive to estradiol action over the prepubertal period. We will focus on neuropeptides which have been shown to be implicated in lordosis behavior. Studies by the group of Micevych have proposed an important role for NPY and beta-endorphin (B-END) neurons in the arcuate nucleus (ARC) in the estradiol-mediated activation of lordosis behavior in female rats. An in vitro study recently showed that kisspeptin directly activates ARC B-END neurons. This is particularly interesting since unpublished results from our laboratory showed that Kp neurons are directly involved in the expression of lordosis behavior. We are thus currently determining the expression of NPY, B-END, and kisspeptin in the ARC as well as μ-opioid receptors MORs in the MPN over the prepubertal period and their possible modulation by prepubertal estradiol treatment. [less ▲]

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