References of "Scientific congresses and symposiums"
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See detailDioxins in our food: Where are we 14 years after the Belgian chicken-gate?
Focant, Jean-François ULg

Conference (2013, October)

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See detailGerminome intracrânien bifocal : la biopsie est-elle toujours indispensable?
KREUTZ, Julie ULg; BONNEVILLE, Jean-François ULg; Potorac, Iulia ULg et al

in Annales d'Endocrinologie (2013, October), 74

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See detailDéveloppement d'un dispositif de trajectographie optique nécessaire pour la caractérisation expérimentale par une approche Euler-Lagrange des écoulements dans des bioréacteurs à cuve agitée
Collignon, Marie-Laure ULg; Delafosse, Angélique ULg; Delvigne, Frank ULg et al

in Récents Progrès en Génie des Procédés (2013, October)

Les bioréacteurs à cuve agitée sont des dispositifs largement utilisés dans l’industrie pharmaceutique. Les performances globales des cultures menées dans ces bioréacteurs dépendent fortement de ... [more ▼]

Les bioréacteurs à cuve agitée sont des dispositifs largement utilisés dans l’industrie pharmaceutique. Les performances globales des cultures menées dans ces bioréacteurs dépendent fortement de l’environnement physico-chimique et hydrodynamique local rencontré par les microorganismes et ce au cours du temps. Pour parvenir à caractériser cet historique de conditions locales rencontrées, une approche Euler-Lagrange doit être adoptée. La difficulté dans ce type d’approche est d’être capable de mesurer de manière fiable la trajectoire suivie par le microorganisme au sein du bioréacteur. Pour ce faire, le Laboratoire de Génie Chimique de l’Université de Liège a conçu un dispositif de trajectographie optique. L’objectif de cet article est de présenter ce dispositif, les développements qui ont été nécessaire à sa mise en œuvre et les résultats obtenus. Le dispositif se compose de deux caméras observant selon deux axes de l’espace un bioréacteur rétro-éclairé par des panneaux leds. La trajectoire suivie par une particule noire en gel d’alginate de calcium de 491 µm de diamètre est construite à partir des images acquises par ces deux caméras préalablement modélisée par un modèle pinhole et traitées par une approche rationnée. La validité des trajectoires mesurées a été prouvée dans un bioréacteur de 20 L mélangé par une hélice TTP en comparant les champs de vitesse moyen et d’énergie cinétique turbulent extraits de la trajectoire avec ceux obtenus par la technique eulérienne Stéréo P.I.V. La convergence de ces deux champs avec le temps d’acquisition de la trajectoire a également été démontrée. [less ▲]

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See detailCertifier la compétence numérique : conception des épreuves
Vandeput, Etienne ULg

in Objets et méthodes d’enseignement de la maternelle à l’université (2013, October)

L'évaluation de la compétence numérique pose de nombreuses questions et, en particulier, celles des épreuves permettant de la certifier.

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See detailInvestigation olfactive de la mort
Focant, Jean-François ULg; Stefanuto, Pierre-Hugues ULg; Brasseur, Catherine ULg et al

in Acta Clinica Belgica (2013, October), 68-6

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See detailImpact of growth rate on the mechanical properties of Douglas-fir grown in Wallonia (Southern Belgium)
Pollet, Caroline; Henin, Jean-Marc; Jourez, Benoît ULg et al

Poster (2013, October)

Timber is traditionally the main purpose of Douglas-fir in Europe. However, some uncertainties remain concerning the sylviculture that should be applied in order to maximise girth growth rate (GR) without ... [more ▼]

Timber is traditionally the main purpose of Douglas-fir in Europe. However, some uncertainties remain concerning the sylviculture that should be applied in order to maximise girth growth rate (GR) without affecting the good mechanical properties of the wood. So, the present study aimed at assessing to what extent the GR of Douglas-firs grown in Wallonia influences the mechanical properties of wood clear samples. The modulus of elasticity (E) and static bending strength (σf) were measured according to NF B51-016 and NF B51-008 and are discussed according to the ring width measured on the samples, as well as on the growth rate of the trees and of the stands, for both juvenile and mature wood. This assessment will help to provide sylviculture guidelines for foresters. The experimental material was derived from 11 Douglas-fir stands distributed all over Wallonia, Southern Belgium. At the time of felling, the age of the stands ranged from 41 to 69 years old. In each stand, six trees were felled, their girth varying from 120cm to 179 cm. As a consequence of the sampling methodology the growth rate of the trees ranged from 3 mm to 7 mm. From the 66 butt logs, 274 and 884 clear samples were taken in the juvenile and mature wood respectively. This research evidenced that: - Whatever the GR, the mean values of E and σf in the juvenile wood are 20% lower than those in the mature wood; - At the tree level, the mean E and σf of the samples taken from trees with ring width>5mm are about 10% lower than those of the samples taken from trees with ring width<5mm, whether considering juvenile or mature wood; - At the stand level and regardless to the type of wood (juvenile/mature), the mean E and σf of the samples originating from stands with mean girth increment>3cm/year are respectively 5% and 9% lower than those of the samples originating from stands with mean girth increment <3cm/year. This observation should lead the forest manager to consider carefully sylvicultural practices that would induce a too fast juvenile growth; high growth rate in the mature wood do not appear to be a problem considering the properties studied here. One should however take into account the impact of the growth rate on the singularities of the boards. [less ▲]

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See detailStudy of the virulence of serotypes 4 and 9 of African horse sickness virus in two mouse models
De la Grandière de Noronha Cotta, Maria Ana ULg; Zonta, William ULg; Mauroy, Axel ULg et al

Poster (2013, October)

African horse sickness (AHSV) is an infectious disease caused by a double stranded positive RNA virus which belongs to the family Reoviridae, genus Orbivirus. The virus has nine serotypes and is ... [more ▼]

African horse sickness (AHSV) is an infectious disease caused by a double stranded positive RNA virus which belongs to the family Reoviridae, genus Orbivirus. The virus has nine serotypes and is transmitted by a culicoides biting midge, principally Culicoides imicola. African horse sickness causes severe morbidity and mortality up to 95 % in horses with severe economic losses. The establishment of an experimental model is needed for the investigation of the pathogenesis of this infection. Two mouse models, interferon-α receptor knock-out mice (A129 KO or IFNAR -/-) and immunocompetent mice (A129 WT), were tested. The viruses used for mice inoculations belonged to the two serotypes which caused epidemics in Europe, serotypes 4 and 9. The virus was inoculated by subcutaneous (SC) route and/or by intra-nasal (IN) route. Whole blood samples were taken from each mouse at regular intervals. The organs (liver, spleen, kidney, lung and brain) were taken at the end of the experiment or when the most affected mice were euthanized. All these samples were tested by a qRT-PCR targeting AHSV genome segment 7. Both serotypes of AHSV were detected by qRT-PCR until three weeks post-infection in blood of IFNAR -/- mice and A129 WT mice infected by SC route. Serotype 4 shows a higher peak of viremia than serotype 9. The peak of viremia was measured between day 2 and day 4 post-infection. These results demonstrate the potential of the immunodeficient mouse model for both clinical and biological features. The setting up of this mouse model has developed a tool for efficient in vivo study to characterize the in vivo virulence of this virus, to monitor the evolution of viral populations during in vivo replication cycles and to test the competence or vectorial capacity of indigenous Culicoides. Research supported by the Belgium Federal Public Service, Health, Food Chain Safety and Environment. [less ▲]

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See detailDemystifying Comprehensive GC
Focant, Jean-François ULg

Conference (2013, October)

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See detailHypothyroïdie infraclinique non auto-immune et statut iodé : étude prospective d'intervention
VALDES SOCIN, Hernan Gonzalo ULg; Tudorescu, A; Lutteri, L et al

in Annales d'Endocrinologie (2013, October), 74

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See detailComet dust profiles from PACS images obtained in the framework of the HSSO project
Opitom, Cyrielle ULg; Bockelée-Morvan, D.; Hutsemekers, Damien ULg et al

Poster (2013, October)

In the framework of the HssO project the Herschel PACS instrument acquired images of 7 comets between June 2010 and February 2013. Three of these comets have been imaged at several heliocentric distances ... [more ▼]

In the framework of the HssO project the Herschel PACS instrument acquired images of 7 comets between June 2010 and February 2013. Three of these comets have been imaged at several heliocentric distances allowing us to follow up the evolution of the dust coma . Radial profiles have been derived for each image. We measured flux densities at 70, 110 and 160 μm in order to determine the comet dust production rate. In some cases, after deconvolution by the instrumental PSF, we might have detected the nucleus signal in the central pixels. [less ▲]

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See detailL’effet des barrages de castors sur le système hydrographique
Denis, Anne-Cécile ULg; Petit, François ULg; Levecq, Yannick ULg et al

Poster (2013, October)

L’augmentation croissante des populations de castors sur nos rivières ces dernières années n’est pas sans conséquence notamment sur la géomorphologie et l’hydrologie des fonds de vallée. En effet, les ... [more ▼]

L’augmentation croissante des populations de castors sur nos rivières ces dernières années n’est pas sans conséquence notamment sur la géomorphologie et l’hydrologie des fonds de vallée. En effet, les barrages construits par les castors constituent des pièges à sédiments susceptibles d’entrainer une incision en aval par déficit en sédiments. La présence de barrages a également pour principal effet de réduire localement la vitesse du courant et de réguler les débits. De plus, les barrages créés par les castors constituent de véritables obstacles à l’écoulement qui peuvent engendrer une modification du tracé du cours d’eau voir du style fluvial. Enfin, en cas de destruction des barrages, le lâcher soudain d’un volume d’eau conséquent peut engendrer un effet « domino » sur les barrages situés en aval entrainant une évacuation importante des sédiments et une incision du cours d’eau. En région Wallonne, il existe plus de 150 barrages de castor. Une analyse récente de leur localisation montre que le castor s’installe principalement sur des rivières ardennaises de dimension modeste mais également sur des rivières de Lorraine et de Famenne. Les barrages sont généralement observés sur des cours d’eau plutôt incisé, en tête de bassin et dans des plaines alluviales plutôt étroites. Différents stades et modes de construction des barrages ont été mis en relation avec la morphologie des rivières. Il en ressort que ces différences impliquent des processus spécifiques de rupture éventuelle de ces barrages. Ces différents aspects ont été plus particulièrement étudiés dans deux rivières ardennaises (la Chavanne et la Lienne). [less ▲]

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See detailLe carcinome parathyroïdien familial : une forme agressive d'hyperparathyroïdie primaire
Tudorescu, A; VROONEN, Laurent ULg; BETEA, Daniela ULg et al

in Annales d'Endocrinologie (2013, October), 74

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See detailWhere is the Conflict? Delving in Walloon Science, Technology and Innovation Politics
Charlier, Nathan ULg; Thoreau, François ULg

Conference (2013, October)

Building on preliminary empirical observations, this paper seeks to analyze a specific feature of science, technology and innovation (STI) policies in Wallonia (Belgium); that is, the apparent lack of ... [more ▼]

Building on preliminary empirical observations, this paper seeks to analyze a specific feature of science, technology and innovation (STI) policies in Wallonia (Belgium); that is, the apparent lack of contestation regarding policy making. Over the last decade, multiple programs and plans were implemented by the regional government. These reforms of STI policy are endorsed by multiple stakeholders, including parliamentary opposition, labor unions and employers’ organizations. Seemingly, Walloon STI policies do not configure as conflict zones. This is remarkable since these programs and plans reconfigure the relationship between science, technological innovation and the market. In other policy fields, opposition is more pronounced and protracted. In other places/times, STI policy is/has been a conflicting matter. This is all the more striking in a context of strategic science advent, where STI is placed at the heart of large regional policy project, building strong ties with economic development and regional identity shaping. Can STS provide the tools and vocabulary to analyze non-conflictual, « cold » situations such as current STI policies and their evolution in Wallonia? Building on semi-structured interviews with key informants, our analysis will pay attention to Walloon contextual specificities as well as macro-level considerations: can dominant, taken-for-granted master narratives such as “knowledge-based economy”, “Regional innovation systems”, or, more recently, “open and responsible innovation” account for the relative smoothness of STI policies? We conclude that there is a felt need for empirical insights to analyze how these master narratives are locally enacted. [less ▲]

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See detailStrength improvement after 3months of resistance training among Parkinson's disease patients
Demonceau, Marie ULg; rodriguez de la cruz, carlos; NAVEAU, Florence ULg et al

in Annals of Physical and Rehabilitation Medicine (2013, October), 56(s1), 196

Objectives.– To assess the feasibility and the effects of a strengthening program for people with Parkinson's disease (PD). Methods.– Fourteen patients with Hoehn and Yahr stage [1] < III of PD were ... [more ▼]

Objectives.– To assess the feasibility and the effects of a strengthening program for people with Parkinson's disease (PD). Methods.– Fourteen patients with Hoehn and Yahr stage [1] < III of PD were allocated to either 24 sessions of strength training (ST group; n = 8) or to a control group (C group; n = 6) for 3 months. Concentric knee muscle strength and a maximal cycling incremental test were performed at baseline and after training. Training consisted of progressive resistive exercises on leg press, leg extension, leg curl, between 50 and 80% of 1RM and was completed by non-instrumented exercises for trunk and upper limbs muscles. Anxiety, depression and quality of life were assessed using questionnaires. An Anova for repeated measures was used for statistical analysis. Results.– Six patients of the ST group (75%) fully completed the program. There were significant “group by time” effects for all knee muscles strength measures of less involved side (P < 0.05). A significant “group by time” effect was also found for knee flexors of the most involved side, but only at angular speed of 180°/s (P = 0.03). Patients of ST group also increased maximal aerobic power (+13%) whereas patients of C group decreased their performances (–9%; “group by time” effect, P = 0.04). No changes in anxiety, depression or quality of life could be highlighted. Conclusions.– The increase of some strength measures in ST group showed that progressive strength training counteracts strength decrease among people with Parkinson's disease. Strengthening also had a positive effect on maximal aerobic power. [less ▲]

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See detailIntroduction et conclusion
Dozo, Björn-Olav ULg; Preyat, Fabrice; Tilleuil, Jean-Louis

Conference (2013, October)

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See detailDRAMATIC OSTEONECROSIS OF THE JAW ASSOCIATED WITH ORAL BIPHOSPHONATES TREATMENT AFTER IMPLANT REMOVAL: A CASE REPORT
FERNANDEZ AYORA, Alberto ULg; HERION, Francine ULg; LAMBERT, France ULg et al

Poster (2013, October)

BACKGROUND Osteoporosis affects millions of elderly patients. Bisphosphonates represent first-line therapy. Osteonecrosis of the jaws in patients treated with bisphosphonates is mostly associated with ... [more ▼]

BACKGROUND Osteoporosis affects millions of elderly patients. Bisphosphonates represent first-line therapy. Osteonecrosis of the jaws in patients treated with bisphosphonates is mostly associated with intravenous bisphosphonates while the incidence associated with oral bisphosphonates is not significant. AIM This report documents a case of bisphosphonate-related osteonecrosis of the jaw (BRONJ) after dental implant removal in an osteoporotic patient treated with alendronate and risedronate for 15 years. MATERIAL AND METHODS An 83-years-old patient with no significant systemic disease underwent implant removal in the first molar left hemimandible position in 2010 due to a peri-implantitis. The surgical procedure was uneventful thought preventive measures were no taken. In June 2011, the patient was referred to our department with a wide bone sequestration of the left mandibular body. A panoramic radiograph showed an increased bone marrow density with bone sequestration. Since then, the patient underwent several courses of antibiotics and conservative therapy, without relief of symptoms. RESULTS Since 2011, the patient has lost 13 teeth in the mandible and the osteonecrosis has disseminated to the entire jaw and the left mandible condyle. The patient has even lost the left hearing. Resective surgery under general anesthesia is not indicated due to the risk because of the age of the patient. CONCLUSION AND CLINICAL IMPLICATIONS Despite the low risk of BRONJ occurrence after implant surgery in oral N-BP users, the fate of dental implants in these patients remains uncertain. Therefore patients at risk must be given a full explanation of the potential risks of implant failure and BRONJ development. Osteonecrosis of the jaws in association with bisphosphonate therapy is a very serious condition with which all dentists should be familiar. Since the treatment of BRONJ is difficult, prevention is the main goal. When the osteonecrosis begins, it can be very painful to the patient, difficult to treat, and can lead to very deleterious sequelae. [less ▲]

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See detailExploiting Socially-Generated Side Information in Dimensionality Reduction
Marcos Alvarez, Alejandro ULg; Yamada, Makoto; Kimura, Akisato

in Proceedings of the 2nd International Workshop on Socially-Aware Multimedia (2013, October)

In this paper, we show how side information extracted from socially-curated data can be used within a dimensionality reduction method and to what extent this side information is beneficial to several ... [more ▼]

In this paper, we show how side information extracted from socially-curated data can be used within a dimensionality reduction method and to what extent this side information is beneficial to several tasks such as image classification, data visualization and image retrieval. The key idea is to incorporate side information of an image into a dimensionality reduction method. More specifically, we propose a dimensionality reduction method that can find an embedding transformation so that images with similar side information are close in the embedding space. We introduce three types of side information derived from user behavior. Through experiments on images from Pinterest, we show that incorporating socially-generated side information in a dimensionality reduction method benefits several image-related tasks such as image classification, data visualization and image retrieval. [less ▲]

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See detailHypoxia in the Black Sea northwestern shelf: From eutrophication to climatic stressors.
Capet, Arthur ULg; Beckers, Jean-Marie ULg; Grégoire, Marilaure ULg

in 40th CIESM congress proceedings (2013, October)

Abstract The dynamics of seasonal hypoxia, which affects the Black Sea north-western shelf since the mid 1970's until present days, is investigated by means of a 3D biogeochemical model. Comparison of the ... [more ▼]

Abstract The dynamics of seasonal hypoxia, which affects the Black Sea north-western shelf since the mid 1970's until present days, is investigated by means of a 3D biogeochemical model. Comparison of the model results with in -situ data reveals that the phenomenon may have been underestimated after the mid 1990's due to the distribution of observations. We investigate the mechanism of hypoxia at seasonal scale, and identify the main drivers of its interannual variability. While high nutrients discharge caused severe hypoxia in the 1980's, it was sustained in the 1990's by the pool of organic matter accumulated during the previous years in the sediments layer. With an increasing intensity, climatic stressors intensifies the response of hypoxia to nutrient discharge, and affect the seasonal dynamics of hypoxia by extending its temporal scale. [less ▲]

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See detailUne infiltration de plasma riche en plaquettes (PRP) pour traiter les tendinopathies rotuliennes supérieures chroniques
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in Annals of Physical and Rehabilitation Medicine (2013, October), 56(Sup 1),

Objective: Jumper’s knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

Objective: Jumper’s knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. Infiltration of platelet-rich plasma (PRP) could be a new therapy for such chronic tendinopathies. Materiel and methods: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months after the infiltration, using a 10-point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA-P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub-maximal eccentric reeducation. Results: Pain during daily activities significantly decreased with time (especially after 6 weeks and continued to a lesser extend up to 3 months). During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. Discussion: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol is efficient to improve symptoms of chronic jumper’s knee in patients non-responsive to classical conservative treatments. [less ▲]

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See detailRevealing Middlebox Interference with Tracebox
Detal, Grégory; Hesmans, Benjamin; Bonaventure, Olivier et al

in ACM/USENIX Internet Measurement Conference (2013, October)

Middleboxes such as firewalls, NAT, proxies, or Deep Packet Inspection play an increasingly important role in various types of IP networks, including enterprise and cellular networks. Recent studies have ... [more ▼]

Middleboxes such as firewalls, NAT, proxies, or Deep Packet Inspection play an increasingly important role in various types of IP networks, including enterprise and cellular networks. Recent studies have shed the light on their impact on real traffic and the complexity of managing them. Network operators and researchers have few tools to understand the impact of those boxes on any path. In this paper, we propose tracebox, an extension to the widely used traceroute tool, that is capable of detecting various types of middlebox interference over almost any path. tracebox sends IP packets containing TCP segments with different TTL values and analyses the packet encapsulated in the returned ICMP message. Further, as recent routers quote, in the ICMP message, the entire IP packet that they received, \tracebox is able to detect any modification performed by upstream middleboxes. In addition, tracebox can often pinpoint the network hop where the middlebox interference occurs. We evaluate tracebox with measurements performed on PlanetLab nodes. Our analysis reveals various types of middleboxes that were not expected on such an experimental testbed supposed to be connected to the Internet without any restriction. [less ▲]

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See detailPrediction of landslide susceptibility in a seismically active high mountain region using data mining methods - a study from Maily-Say, Kyrgyzstan
Braun, Anika; Fernandez-Steeger, Tomas; Havenith, Hans-Balder ULg et al

in Reicherter, Klaus; Rudersdorf, Andreas; Grützner, Christoph (Eds.) Seismic Hazard, Critical Facilities and Slow Active Faults, Proceedings (2013, October)

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See detailNetwork Fingerprinting: TTL-Based Router Signatures
Vanaubel, Yves ULg; Pansiot, Jean-Jacques; Mérindol, Pascal et al

in ACM/USENIX Internet Measurement Conference (2013, October)

Fingerprinting networking equipment has many potential applications and benefits in network management and security. More generally, it is useful for the understanding of network structures and their ... [more ▼]

Fingerprinting networking equipment has many potential applications and benefits in network management and security. More generally, it is useful for the understanding of network structures and their behaviors. In this paper, we describe a simple fingerprinting mechanism based on the initial TTL values used by routers to reply to various probing messages. We show that main classes obtained using this simple mechanism are meaningful to distinguish routers platforms. Besides, it comes at a very low additional cost compared to standard active topology discovery measurements. As a proof of concept, we apply our method to gain more insight on the behavior of MPLS routers and to, thus, more accurately quantify their visible/invisible deployment. [less ▲]

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See detailAnalysis of the distribution of landslides and landslide dams induced by the Wenchuan Earthquake
Fan, Xuanmei; van Westen, Cees J.; Havenith, Hans-Balder ULg

in Reicherter, Klaus; Rudersdorf, Andreas; Grützner, Christoph (Eds.) Seismic Hazard, Critical Facilities and Slow Active Faults, Proceedings (2013, October)

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See detailANAEROBIC DIGESTION WITH BIOHYDROGEN PRODUCTION FROM ORGANIC WASTES : STATE-OF-THE ART
Hiligsmann, Serge ULg; Beckers, L.; Hamilton, C. et al

in Proceedings Sardinia 2013 (2013, October)

Hydrogen (H2) is being considered as an ideal and clean energy carrier since the utilization of hydrogen, either via combustion or via fuel cells, results in pure water. However, currently its production ... [more ▼]

Hydrogen (H2) is being considered as an ideal and clean energy carrier since the utilization of hydrogen, either via combustion or via fuel cells, results in pure water. However, currently its production relies mainly (i.e. 95%) on fossil fuels. The recent advances to produce biohydrogen from renewable sources such as biomass and particularly by fermentation of carbohydrate-rich substrates from agriculture and agro-industries appear promising. Such a process called “dark fermentation” enables both organic waste treatment and renewable energy production to be coupled. The soluble metabolites, mainly acetate and butyrate, contained in the spent medium of the dark fermentation bioreactor may be efficiently converted to methane in a second anaerobic digester treating other carbon sources. The paper reviews the state-of-the art on the challenges and prospective applications of dark fermentation as a first step of anaerobic digestion of municipal solid wastes to produce H2 and CH4. [less ▲]

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See detailActualités thérapeutiques dans la prise en charge des tendinopathies
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Forthomme, Bénédicte ULg et al

in Annals of Physical and Rehabilitation Medicine (2013, October), 56(Sup 1), 050-003

“Conventional” treatments of tendinopathies are generally employed empirically to fight pain and inflammation but they do not modify the histological structure of the tendon. However, these treatments are ... [more ▼]

“Conventional” treatments of tendinopathies are generally employed empirically to fight pain and inflammation but they do not modify the histological structure of the tendon. However, these treatments are not completely satisfactory and the recurrence of symptoms is common. In contrast to the passive pattern of many therapies dedicated to tendon disorders, some authors have promoted an eccentric training mode. Such active eccentric training programs are aimed at thwarting an aetiopathogenic theory proposing insufficient tensile strength of the tendon exposed to external loads which could progressively damage it. Though the literature remains incomplete on tendon architecture remodelling and real histological adaptations following an adapted eccentric training, clinical results following such therapy appear promising. Due to its noninvasiveness, low complication rate and high applicability combined with good results, extracorporeal shock wave therapy has become a well known option within the therapeutic spectrum for many tendinopathies. More specifically, it has been successfully applied in chronic tendinopathy resistant to a conservative training program including eccentric exercises. Platelets release different cytokines and growth factors that could promote angiogenesis, tissue remodelling (bone, skin etc.), and wound healing. Platelet-rich plasma (PRP) is obtained by centrifuging autologous blood to have a high concentration of platelets depending on the isolation method. For this reason, different PRP preparation techniques cannot provide a consistently identical final product, but there is currently no international consensus on this issue. Despite the proven efficacy of PRP tissue regeneration in labs, there is currently little tangible clinical evidence for chronic tendon disorders. The few studies that have been performed appear unlikely to be comparable. Up to now, randomised controlled studies with appropriate placebo groups are needed to determine the real effectiveness of PRP for treating chronic tendon conditions. However, this therapeutic option remains very popular in sports, and many top athletes are using it in case of musculoskeletal conditions. What is more, it has been removed from the doping lost of the World AntiDoping Agency. Other new therapeutic options (infiltrations of polidocanol, hyaluronic acid, botulinum toxin, patches of derivatives Nitro...) for treating tendinopathies are also discussed in this review. [less ▲]

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See detailBioclimatic Design in Casablanca (Morocco): Decision Support through Building Performance Simulation
Attia, Shady ULg; Geoffrey, van Moeseke

in Proceedings of the 4th Biennial subtropical cities conference (2013, October)

In this paper, bioclimatic design strategies in Moroccan architecture have been analyzed for the city of Casablanca. The aim of this study is to enable architects to re-understand the lessons of tradition ... [more ▼]

In this paper, bioclimatic design strategies in Moroccan architecture have been analyzed for the city of Casablanca. The aim of this study is to enable architects to re-understand the lessons of tradition, because the way towards bioclimatic architecture should start by understanding vernacular architecture. The first part of the paper presents climate analysis and a set of bioclimatic principles addressing orientation, shading, thermal mass, insulation and natural ventilation as a mean for passive cooling. The second part explores the potential of implementing the Passivhaus Standard in Casablanca. Based on a validated building model, the performance of one of an apartment, satisfying the Passivhaus Standard has been determined by means of building performance simulation. The analysis evaluated different bioclimatic strategies and examined the transfer of the Passivhaus concept to hot warm climate, while ensuring thermal comfort during summer. Results showed that the studied building concept, comprising several bioclimatic design strategies can be transferred, with appropriate adaptations, also to hot climates. Finally the study developed significant recommendation that support architects with principles and strategies for bioclimatic design. [less ▲]

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See detailClustering-Based Anomaly Detection in Multi-View Data
Marcos Alvarez, Alejandro ULg; Yamada, Makoto; Kimura, Akisato et al

in Proceedings of the 22nd International Conference on Information and Knowledge Management (2013, October)

This paper proposes a simple yet effective anomaly detection method for multi-view data. The proposed approach detects anomalies by comparing the neighborhoods in different views. Specifically, clustering ... [more ▼]

This paper proposes a simple yet effective anomaly detection method for multi-view data. The proposed approach detects anomalies by comparing the neighborhoods in different views. Specifically, clustering is performed separately in the different views and affinity vectors are derived for each object from the clustering results. Then, the anomalies are detected by comparing affinity vectors in the multiple views. An advantage of the proposed method over existing methods is that the tuning parameters can be determined effectively from the given data. Through experiments on synthetic and benchmark datasets, we show that the proposed method outperforms existing methods. [less ▲]

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See detailThe usability of green building rating systems in hot arid climates: A case study in Siwa, Egypt
Attia, Shady ULg; Dabaieh, Marwa

in Proceedings of the 4th Biennial subtropical cities conference (2013, October)

In the last ten years there has been a proliferation of regional building rating systems across the Middle East (ME). Most those emerging rating systems and labels emulate the British and American rating ... [more ▼]

In the last ten years there has been a proliferation of regional building rating systems across the Middle East (ME). Most those emerging rating systems and labels emulate the British and American rating systems BREEAM and LEED that emerged in industrial countries context with an impact reduction paradigm. Thus they are neglecting the local historic, climatic, economic, technological, cultural and social context of the ME. This paper presents a case study of a recently constructed eco-lodge, AlBabenshal, in Siwa, Egypt, that performs beyond the existing rating systems requirements. The paper illustrates the environmental and sustainability design strategies adapted to AlBabenshal Lodge buildings’ context. In this study, the usability of existing rating systems in the ME is surveyed and their response to climate, occupants and society is evaluated. The paper presents a set of sustainability principles addressing (1) the site, (2) water, (3) energy, (4) resources, (5) comfort, (6) heritage and (7) social responsibility. In addition, the building is examined across the environmental criteria of LEED, Estidama Pearl Rating System and the Egyptian Green Pyramid Rating System (GPRS). Results showed that the building failed to comply with the three rating systems despite its sustainability and despite winning the Egyptian Hassan Fathy Award for environmental design. The paper elaborates on this conflict and presents recommendations to improve and adapt the questioned rating systems [less ▲]

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See detailNursing adherence on ventilator care bundle in a burn unit.
DEPAYE, Nicolas ULg; ROUSSEAU, Anne-Françoise ULg; LAPORT, Virginie ULg et al

Conference (2013, September 30)

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See detailLa météorologie et la climatologie dans la politique scientifique belge
Pirot, Pascal ULg

Conference (2013, September 28)

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See detailPères gays en transition: croyances, relations et pistes thérapeutiques
D'Amore, Salvatore ULg

Conference (2013, September 28)

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See detailWP8 and WP9 developments: Data-Interpolating Variational Analysis (Diva) developments
Troupin, Charles ULg; Barth, Alexander ULg; Ouberdous, Mohamed et al

Conference (2013, September 27)

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See detailMolecular mechanisms of type I collagen-induced apoptosis in breast carcinoma cells
Maquoi, Erik ULg; Assent, Delphine ULg; Foidart, Jean-Michel ULg et al

Poster (2013, September 27)

Objective: As invading breast carcinoma cells breach the underlying basement membrane, they become confronted with a dense three-dimensional reactive stroma dominated by type I collagen. To develop ... [more ▼]

Objective: As invading breast carcinoma cells breach the underlying basement membrane, they become confronted with a dense three-dimensional reactive stroma dominated by type I collagen. To develop metastatic capabilities, invading tumour cells must acquire the capacity to negotiate this hostile microenvironment. By enmeshing cells in a dense fibrillar network, type I collagen acts as a physical barrier for cell migration as well as an endogenous antigrowth signal, partly by inducing apoptosis in epithelial cells. Aberrant cell survival resulting from an acquired resistance toward apoptosis represents a prominent hallmark of cancers. However, the molecular mechanisms implicated in collagen-induced apoptosis remain poorly defined. Here, we investigate the molecular mechanisms by which type I collagen induces apoptosis in breast carcinoma cells and identify MMP-14, a membrane-anchored matrix metalloproteinase, as a key anti-apoptotic factor. Methods: To investigate the induction of apoptosis by collagen, human breast adenocarcinoma MCF-7 cells overexpressing or not MMP-14 were plated on plastic plates or embedded within three dimensional type I collagen gels (Col3D). Cell death was evaluated by measuring cytoplasmic histone-associated DNA fragments (Cell Death Detection ELISA). The percentage of cells with an apoptotic nuclear morphology was also determined. The interactions between cancer cells and Col3D were analyzed by confocal microscopy and the impact of Col3D on the transcriptome of cancer cells was investigated using Illumina HT-12 BeadArrays. Results: When cultured within Col3D gels, MCF-7 cells displayed a round morphology and a cell death characterized by a Z-VAD-FMK-dependent chromatin condensation, nuclear segmentation and oligonucleosomal DNA fragmentation was induced. Transfection of MCF-7 cells with MMP-14 cDNA promoted the interactions between cells and collagen and prevented apoptosis. A transcriptomic analysis revealed that culturing MCF-7 cells within Col3D altered the expression of about 700 genes, irrespective of MMP-14 expression. Col3D modulated the expression of several apoptosis-related genes. Interestingly, MMP-14 activity was sufficient to prevent the Col3D-dependent induction of Bcl2-Interacting Killer (BIK), a pro-apoptotic member of the Bcl-2 family. Conclusions: Our results shed light on the molecular mechanisms by which a collagen-rich microenvironment triggers apoptosis in invading breast cancer cells. Furthermore, we demonstrate that MMP-14 promotes tumour progression by circumventing apoptosis. [less ▲]

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See detailFluidothérapie chez le veau
Sartelet, Arnaud ULg; Lecomte, Denis; Theron, Léonard ULg et al

Conference (2013, September 27)

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See detailPILOT PROJECT IN CHR-LIEGE: INVITING SIBLINGS OF CHILDREN WITH CANCER TO A CREATIVE AND EXPRESSIVE WEEK-END WITH PSYCHOLOGISTS AND ONCOLOGIST
Forget, Patricia; Badot, Isabelle; Missotten, Pierre ULg et al

Poster (2013, September 27)

The siblings week end with the psycho-medical team was highly successful It opens another way to improve the care of the siblings Questionnary forms should be developped in the future to evaluate the real ... [more ▼]

The siblings week end with the psycho-medical team was highly successful It opens another way to improve the care of the siblings Questionnary forms should be developped in the future to evaluate the real psychological impact [less ▲]

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See detailLondon or New York? Mobility Options of Young Belgians in Times of Crises
Lafleur, Jean-Michel ULg

Conference (2013, September 26)

Since the beginning of the financial and economic crisis, Belgium has experienced a new influx of Southern European immigration while continuing to receive large numbers EU citizens proceeding from ... [more ▼]

Since the beginning of the financial and economic crisis, Belgium has experienced a new influx of Southern European immigration while continuing to receive large numbers EU citizens proceeding from Central and Eastern European Member States. This reality is however hiding the fact that, simultaneously, a large number of Belgian citizens continue to leave the country every year. Belgian emigration has indeed tripled between 1970 and 2011 and nowadays about 35.000 citizens leave the country every year. Despite the increase in the number of Belgian pensioners retiring abroad, the modal age of departure remains low (26 years old). In this paper, I propose to examine two related questions on the emigration of young Belgians. First, what are the motivations of young Belgians to leave their home country today even though Belgium seems to be resisting better than most Member States to the economic crisis? Second, what drives Belgian emigrants to specific cities abroad? [less ▲]

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See detailConception et utilisation de « seepage-meters » artisanaux pour l'étude des interactions «rivière – eaux souterraines » au Burkina Faso
Sauret, Elie ULg; Nitcheu, Martial; Orban, Philippe ULg et al

Conference (2013, September 25)

Situé à l'ouest du Burkina Faso dans la région de Bobo Dioulasso, le bassin du Kou présente un contexte climatique et hydro(géo)logique, favorables à l'accumulation et à la mobilisation d’importantes ... [more ▼]

Situé à l'ouest du Burkina Faso dans la région de Bobo Dioulasso, le bassin du Kou présente un contexte climatique et hydro(géo)logique, favorables à l'accumulation et à la mobilisation d’importantes ressources en eaux souterraines et de surface, en témoigne, les sources de Nasso/guinguette au centre de bassin qui ont un débit d'environ 6000 m3/h. D'un point de vue hydrogéologique, les sources qui constituent les points d’émergences des formations aquifères profonds du bassin se déchargent dans la rivière (Kou) et assurent ainsi sa pérennité tout au long de l’année. D’amont en aval du bassin, le Kou est largement exploité par les agriculteurs installés ça et là de part et d’autre de ses rives. Malheureusement, au cours des vingt dernières années un afflux important de nouveaux agriculteurs a constitué une pression sur les ressources en terres et en eau du bassin, occasionnant une concurrence aigue à tendance conflictuelle entre les différents exploitants agricoles autour de la rivière. Pour mieux caractériser et, quantifier l'évolution dans le temps des ressources en eau du Kou , une série de tests et études hydrogéologiques prenant en compte les deux autres réservoirs : les aquifères sédimentaires profonds et la plaine alluviale déployé tout au long de la rivière, ont été réalisées. Les techniques de mesure directe par seepage meters des volumes d’eau échangés à l’interface «rivière - nappe» ont permis de quantifier localement les transferts d’eau et déceler les directions et sens des échanges entre les différents réservoirs. Les résultats obtenus ont montré qu’il existe des sections où le Kou gagne (1.5 m3/s) ou perd (-0.10 m3/s) de l’eau au profit ou au détriment des eaux souterraines (aquifères sédimentaires profonds et plaine alluviale). Ces résultats ont été validés par des analyses hydrochimiques des échantillons d’eau prélevés. [less ▲]

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See detailAfter-Care : from Johannesburg 1930 to the Sixties in Western Coalfield Societies
Geerkens, Eric ULg

Conference (2013, September 25)

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See detailEmpty Container Management in the Benelux Waterways
Salmon, Frédéric ULg; Limbourg, Sabine ULg

in Pianic Smart Rivers 213 (2013, September 25)

The scientific contribution of this paper is the development of a model for empty container management in the hinterlands of the ports of Antwerp and Rotterdam. The objective of the proposed model is to ... [more ▼]

The scientific contribution of this paper is the development of a model for empty container management in the hinterlands of the ports of Antwerp and Rotterdam. The objective of the proposed model is to minimize the total operational cost while satisfying the demand for empty containers. This goal is achieved by choosing the most efficient transportation mode between a seaport and its hinterland: road, inland waterways or intermodal transport. Moreover, to fit the real-life operation and management as well as possible, our model also includes container substitution and container leasing options. [less ▲]

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See detailQuelle est l’influence de la culture de la génération C sur le rapport au travail et au management ?
Cusumano, Christophe ULg

Conference (2013, September 25)

Generation C, also known as generation Z, is a term used to designate people born between 1987 and 1994. This study aims to answer the following question: Is it generation C merely a subgroup of ... [more ▼]

Generation C, also known as generation Z, is a term used to designate people born between 1987 and 1994. This study aims to answer the following question: Is it generation C merely a subgroup of generation Y, or is it a separate group? The perspective of this study is focusing on the codes, the moral values, the attitudes, and the representation towards work and management of generation C. After a brief review of the concept of generation and an overview of the scientific literature on the topic of the baby boom generation, generation X, Y, and C, the results of the empiric study will be presented. This study is based on one hand on interviews and focus groups, which allowed us to question 100 people, as well as, on the other hand on a survey answered by 400 individuals. The conclusion is that there is a moderate influence of generations on the relationship of work and management. Generation C is characterized by a heightening of the traits of generation Y. It does distinguish itself on a qualitative manner on several aspects, such as its relationship towards technology, on the management follow up, and on the perception if the company's boundaries. [less ▲]

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See detailCharacterization of tumor heterogeneity using bioimage informatics and 3D computational modeling
Stamatelos, Spyros; Carlier, Aurélie ULg; Kim, Eugene et al

Conference (2013, September 25)

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See detailDosage des catécholamines et métabolites par LCMS-MS
LE GOFF, Caroline ULg

Conference (2013, September 25)

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See detailSPATIODATA, une approche alternative pour la gestion des données spatialisées relatives aux bâtiments
Carré, Cyril ULg; Delfosse, Vincent ULg; Billen, Roland ULg et al

in Thibaud; Gourmelon; Gensel, Jérôme (Eds.) et al SAGEO 2013 - Conférence internationale de Géomatique et d'analyse spatiale - ACTES de la Conférence (2013, September 25)

There are an increasing number of mobile applications supporting specific activities related to the indoor building environment. SpatioData is a research project aiming at the development of a ... [more ▼]

There are an increasing number of mobile applications supporting specific activities related to the indoor building environment. SpatioData is a research project aiming at the development of a collaborative platform for the effective sharing of building-related data and supporting a wide range of different activities. After presenting the initial requirements of the system, this paper provides a review of the standards for the building modeling and the commercial solutions currently available. Then, it describes the SpatioData building model, as well as the general system architecture. [less ▲]

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See detailMise en oeuvre du formalisme multifractal sur les espaces Snu
Kleyntssens, Thomas ULg; Nicolay, Samuel ULg

Conference (2013, September 24)

When considering very irregular functions, it does not make sense to try to characterize the pointwise irregularity because it can change from one point to another. It is more interesting to compute the ... [more ▼]

When considering very irregular functions, it does not make sense to try to characterize the pointwise irregularity because it can change from one point to another. It is more interesting to compute the spectrum of singularities, ie "the size'' of the set of points which share the same pointwise irregularity; by size, one means the Hausdorff dimension. To compute the spectrum of singularities in practice, we use a multifractal formalism. In 1885, Frisch and Parisi have proposed a first formalism. Its main default is that it always leads to a concave spectrum. In 2004, Stéphane Jaffard has introduced the Snu spaces. They lead to a new multifractal formalism which can detect non concave spectra. In practice, one has to avoid the concept of limit and to deal with finite size effects (for example, one can only calculate a finite number of wavelet coefficients). I present a method to determine the spectrum based on the Snu spaces and I illustrate it numerically on theoretical functions. [less ▲]

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See detailResorcinol-Formaldehyde Carbon Xerogels as Anode Material for Lithium-Ion Battery: Synthesis, Grinding and Coating on Current Collector
Piedboeuf, Marie-Laure ULg; Léonard, Alexandre ULg; Pirard, Jean-Paul ULg et al

Poster (2013, September 24)

Rechargeable lithium-ion batteries show great advantages over traditional batteries and are extensively used for consumer electronic devices due to their high energy density and long cycle life. However ... [more ▼]

Rechargeable lithium-ion batteries show great advantages over traditional batteries and are extensively used for consumer electronic devices due to their high energy density and long cycle life. However, the improvement of performance of current lithium-ion batteries requires the optimization of the materials used (electrolyte and electrodes). Therefore, tremendous efforts have been dedicated to exploring new materials with high capacity, excellent cycling performance, low cost and high safety features [1-3]. As an example, carbon xerogels are promising candidates in the development of new high performance C-based anode materials for Li-ion batteries, since such carbonaceous materials show very small changes of volume during the charge/discharge process, providing a long cycle life. Nevertheless, hard carbons also exhibit quite high irreversible capacity losses due to their intrinsic high microporosity [4]. To overcome these disadvantages, the structural and textural characteristics need to be carefully controlled. Also, due to the different morphology of these materials compared to graphite, the deposition of carbon xerogels on current collectors needs to be studied in detail. In this work, porous carbon xerogels have been synthesized from Resorcinol-Formaldehyde mixtures by adjusting the pH of the solution in order to obtain different mesopore sizes. Monoliths of carbon xerogels are obtained after drying of the polymer gel and pyrolysis [5]. These monoliths have been ground by two different methods and particle size distributions were measured by granulometry. Mercury intrusion porosimetry and nitrogen adsorption techniques (BET) have been used to characterize the pore texture of the monolithic and the powder materials. Different conditions have been used for the mixing of carbon xerogels with a binder and a solvent to form slurries. The latter have been cast on a copper foil using bar coating with different openings. After evaporation of the solvent, the resulting coatings were analyzed using scanning electron microscopy (SEM) for the morphology and their thickness was monitored by profilometry. First results indicate that the method of grinding has no influence on the final particle size distribution of the powder. The structural features of the carbon xerogels is well preserved for particles down to one micrometer. Nevertheless, a study of grinding duration shows that additional particles with sizes close to that of the porosity of the carbon appear. As a consequence, the grinding conditions were chosen so as to obtain a compromise between particles small enough to realize a coating on a current collector and particles large enough to maintain the carbon gel structural characteristics. References 1) Goodenough J.B., Kim Y. J. Power Sources 2011; 196(16): 6688-6694. 2) Bruce P.G. Solid State Ionics 2008; 179: 752-760. 3) Cairns A. J., Albertus P. Ann. Rev. Chem. Biomol. Eng. 2010; 1: 299-320. 4) Tran T., Yebka B., Song X., Nazri G., Kinoshita K., Curtis D. J. Power Sources 2000; 85: 269-278. 5) Job N., Théry A., Pirard R., Marien J., Kocon L., Rouzaud J., Béguin F., Pirard J. Carbon 2005; 43: 2481-2494. [less ▲]

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See detailAnalytical study of “La Famille Soler” by Picasso: from the Blue Period to Cubism
Defeyt, Catherine ULg; Vekemans, Bart; Vandenabeele, Peter et al

Poster (2013, September 23)

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See detailApplication of the Data-Interpolating Variational Analysis (DIVA) to sea-level anomaly measurements in the Mediterranean Sea
Troupin, Charles ULg; Barth, Alexander ULg; Beckers, Jean-Marie ULg et al

Poster (2013, September 23)

In ocean sciences, numerous techniques are available for the spatial interpolation of in situ data. These techniques mainly differ in the mathematical formulation and the numerical efficiency. Among them ... [more ▼]

In ocean sciences, numerous techniques are available for the spatial interpolation of in situ data. These techniques mainly differ in the mathematical formulation and the numerical efficiency. Among them, DIVA, which is based on the minimization of a cost function using a finite-element technique (figure 1). The cost function penalizes the departure from observations, the smoothness or regularity of the gridded field and can also include physical constraints. The technique is particularly adapted for the creation of climatologies, which required a large to several regional seas or part of the ocean to generate hydrographic climatologies. Sea-level anomalies (SLA) can be deduced from satellite-borne altimeters. The measurements are characterized by a high spatial resolution along the satellite tracks, but often a large distance between neighbour tracks. This implies the use of simultaneous altimetry missions for the construction of gridded maps. An along-track long wave-length error (correlated noise, e.g. due to orbit, residual tidal correction or inverse barometer errors) also affects the measurement and has to be taken into account in the interpolation. In this work we present the application and adaptation of Diva to the analysis of SLA in the Mediterranean Sea and the production of weekly maps of SLA in this region. Determination of the parameters The two main parameters that determines an analysis with DIVA are the correlation length (L) and the signal-to-noise ratio (SNR). Because of the particular spatial distribution of the measurements, the tools implemented in Diva for the analysis parameter determination tend to underestimate L and overestimate SNR, leading to noisy analysis (the observation constraint dominates the regularity constraint). Some adaptations of the tools are necessary to solve this issue. Numerical cost Because of the large number of observations to be processed (in comparison with in situ measurements on a similar period), the interpolation method employed is expected to be numerically efficient. Improvements in the implementation of Diva further improved the numerical performance of the method, especially thanks to the use of a parallel solver for the matrix inversion. The performance of finite-element mesh generator was also enhanced, so that interpolation of a data set of more than 1 million data points on a 100-by-100 grid can be performed in a few minutes on a personal laptop. Analysis and error field The analysis and error fields obtained over the Mediterranean Sea are compared with the available gridded products from AVISO. Different ways to compute the error field are compared. The impact of the use of multiple missions to prepare the gridded fields is also examined. [less ▲]

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See detailImproved District Heating Network Operation by the Integration of High Temperature Heat Pumps
Sartor, Kevin ULg; Lemort, Vincent ULg; Dewallef, Pierre ULg

in Digital proceedings of the 8th Conference on Sustainable Development of Energy, Water and Environment Systems - SDEWES (2013, September 23)

Biomass Combined Heat and Power (CHP) plants connected to district heating networks are a very good opportunity to increase the share of renewable sources into energy systems. Frequently, important ... [more ▼]

Biomass Combined Heat and Power (CHP) plants connected to district heating networks are a very good opportunity to increase the share of renewable sources into energy systems. Frequently, important consumers are connected to ensure a stable base demand of heat throughout the year but they often have higher requirements in terms of temperature (i.e., steam) which involves high level of temperatures in the district heating network during the whole year and high levels of heat losses in the network. This contribution presents the possibility to decrease the level of temperature at which the district heating network operates and to use high temperature heat pumps connected locally at the consumption point to produce steam when needed. An investigation of the global design and integration through thermodynamic simulation models is realized for the University of Liège district heating network. This study is intended to determine the heat pump coefficient of performance and, therefore, to assess the balance between the savings in terms of heat losses and the additional heat pump electricity consumption. [less ▲]

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See detailAPI design for machine learning software: experiences from the scikit-learn project
Buitinck, Lars; Louppe, Gilles ULg; Blondel, Mathieu et al

Conference (2013, September 23)

scikit-learn is an increasingly popular machine learning library. Written in Python, it is designed to be simple and efficient, accessible to non-experts, and reusable in various contexts. In this paper ... [more ▼]

scikit-learn is an increasingly popular machine learning library. Written in Python, it is designed to be simple and efficient, accessible to non-experts, and reusable in various contexts. In this paper, we present and discuss our design choices for the application programming interface (API) of the project. In particular, we describe the simple and elegant interface shared by all learning and processing units in the library and then discuss its advantages in terms of composition and reusability. The paper also comments on implementation details specific to the Python ecosystem and analyzes obstacles faced by users and developers of the library. [less ▲]

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See detailEinleitung
Brüll, Christoph ULg; Rohrkamp, René

Conference (2013, September 21)

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See detailSerial order working memory is impaired in developmental dyscalculia
Attout, Lucie ULg

Conference (2013, September 21)

Several studies explored associations between impairments in verbal working memory (WM) and numerical cognition, but with inconclusive findings. The present study explored verbal WM impairment in children ... [more ▼]

Several studies explored associations between impairments in verbal working memory (WM) and numerical cognition, but with inconclusive findings. The present study explored verbal WM impairment in children with developmental dyscalculia, by adopting the critical distinction between WM for item information (the items to be retained) and WM for order information (the order of the items within a list). We hypothesized that especially WM for order should be related to impaired numerical abilities, given that recent studies suggest close interactions between the representation of order information in WM and ordinal numerical processing. We investigated item and order WM capacities as well as basic numerical processing abilities in 16 children with dyscalculia (age: 8-11 years) and 16 typically developing children matched on age, IQ and reading abilities. WM for order information was assessed via a serial order reconstruction task which maximized serial order storage requirements. WM for item information was assessed using a single monosyllabic nonword delayed repetition maximizing phonological item processing. We observed that the group with dyscalculia performed significantly slower than the control group in symbolic order and magnitude judgment task, while not being slowed on general measures of processing speed. Dyscalculic participants also performed significantly poorer and with less precision than controls in the order WM task, but not in the item WM task. These results highlight a specific impairment for WM for serial order in dyscalculia, and could reflect a more general serial order processing impairment for both WM and numerical domains. [less ▲]

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See detailOrthographic learning in adult skilled readers
Binamé, Florence ULg; Poncelet, Martine ULg

Poster (2013, September 21)

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See detailPerception du pouvoir entre visiteurs et visités dans la pratique du tourisme dit « ethnique »: Au-delà des oppositions, authentique / simulacre
Lekane Tsobgou, Dieudonné ULg; Schmitz, Serge ULg

Poster (2013, September 20)

La pratique du tourisme est prise sous l'angle d'une confrontation entre les peuples « visiteurs » et les peuples « visités » (Demanget, 2007). L’exotisme culturel des populations autochtones est la ... [more ▼]

La pratique du tourisme est prise sous l'angle d'une confrontation entre les peuples « visiteurs » et les peuples « visités » (Demanget, 2007). L’exotisme culturel des populations autochtones est la principale attraction (Harron et al. 1992). Ainsi, une modification de l’équilibre et une rencontre bilatérale semblent plus opaques. Dès lors, les produits authentiques ou les productions instrumentalisées déterminent la position de pouvoir détenus par les visiteurs ou par les visités. Les promoteurs touristiques cherchent avant tout leur gain d’où l’offre parfois des produits issus de simulacre aux visiteurs en mal d’exotisme. Comment illustrer les jeux de pouvoir et de marchandage qui organisent les rencontres plus ou moins authentiques entre visités et touristes ? Les pratiques du tourisme ethnique en Afrique (Cameroun, Madagascar) et en Asie ( Birmanie, Thailande) nous ont servi d'outils d'analyse et d'expérimentation du jeu de pouvoirs entre visités et visiteurs. [less ▲]

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See detailLa querelle autour d'une fondation psychologique des sciences historiques
Dewalque, Arnaud ULg

Conference (2013, September 20)

La psychologie peut-elle être considérée comme le « fondement » (Grundlage) des sciences de l’esprit ? Si oui, à quelles conditions ? Cette question a profondément divisé le paysage philosophique au ... [more ▼]

La psychologie peut-elle être considérée comme le « fondement » (Grundlage) des sciences de l’esprit ? Si oui, à quelles conditions ? Cette question a profondément divisé le paysage philosophique au tournant du XXe siècle. D’un côté, certains auteurs, comme le brentanien Carl Stumpf (1848-1936), l’élève de Dilthey, Max Frischeisen-Köhler (1878-1923), ou celui de Benno Erdmann, Erich Becher (1882-1929), répondent par l’affirmative : oui, la psychologie est la discipline fondamentale des sciences de l’esprit, comme la physique ou la mathématique est la discipline fondamentale des sciences de la nature. D’autres auteurs, en revanche, contestent que la psychologie puisse fonder les sciences historiques et réclament un autre fondement, non psychologique. C’est le cas, exemplairement, des néokantiens de l’école de Bade, Wilhelm Windelband (1848-1915) et Heinrich Rickert (1863-1936). Dans cet exposé, je suggère que l’approche psychologique présente certains avantages. L’intuition fondamentale derrière l’idée d’une fondation psychologie de la connaissance, à mon sens, est une intuition "empiriste" : l’expérience vécue est l’origine ou la source des concepts qui nous servent à connaître le monde, c’est-à-dire à expliquer le monde naturel et à comprendre le monde historique. Connaître, c’est transférer ou appliquer des « concepts psychologiques primaires », tirés de l’expérience vécue, à des objets du monde. [less ▲]

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See detailIntroduction
Bilhaut, Anne-Gaël ULg

Conference (2013, September 20)

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See detailHow to perform the most minimal invasive cholecystectomy?
DETRY, Olivier ULg

Conference (2013, September 20)

Twenty years ago, laparoscopy has totally transformed the surgical approach of the gallbladder. For those who were not in surgery at that time, it has to be reminded that most open cholecystectomies ... [more ▼]

Twenty years ago, laparoscopy has totally transformed the surgical approach of the gallbladder. For those who were not in surgery at that time, it has to be reminded that most open cholecystectomies performed in the 80’s required nasogastric tube for several days, surgical drain, and 5 to 8 days of hospitalisation. For these obvious advantages, laparoscopic cholecystectomy has become the “Gold Standard” without evidence by a randomised controlled study comparing open and laparoscopic techniques. These last years, some groups proposed variations of laparoscopic cholecystectomies that they presented as less invasive. In robotic surgery, the Da-Vinci device has been proposed without significant improvement since more than 10 years. To date, no interest of this Da-Vinci robot has been demonstrated in abdominal surgery. Its cost for acquisition, its yearly fee and the cost for each use render its use without proof of results totally inappropriate. Single-Incision Laparoscopic Surgery (SILS) has also been described to perform cholecystectomy with only one larger umbilical incision. Until now, no superiority of SILS on classical cholecystectomy has been demonstrated. The Natural Orifice Transluminal Endoscopic Surgery (NOTES) proposes to use the vagina, the stomach or the colon to remove the gallbladder. No prospective controlled comparison has proved the superiority of these approaches that sometimes do not reach common sense or usual surgical principles. What is a minimal invasive cholecystectomy? A safe and un expensive cholecystectomy, with a good anatomical exposure, a cholangiography, and a good surgical comfort allowing to perform several procedures in the same day; a cholecystectomy that can be performed as a day-case without complications; a cholecystectomy that can be performed laparoscopically in acute settings; a cholecystectomy without the risk of postoperative incisional hernia. In necessary, in young and thin woman, laparoscopic cholecystectomy may be performed using 2 mm trocars that allow a good triangulation but with minimal scars. [less ▲]

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See detailStudy of the estrogenicity of pure compound migrate from plastic food contact materials
Simon, Coraline ULg; Oghena, M.; Covaci, A. et al

Poster (2013, September 19)

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See detailNitrous oxide emissions using quantum cascade laser spectrometry over a production crop: preliminary results
SALERNO, Giovanni ULg; Aubinet, Marc ULg; Joly, Joly et al

Poster (2013, September 18)

Amongst the greenhouse gases, nitrous oxide is recognized as having the greatest greenhouse forcing potential and as being the third in terms of radiative forcing. Agriculture is known to be the major ... [more ▼]

Amongst the greenhouse gases, nitrous oxide is recognized as having the greatest greenhouse forcing potential and as being the third in terms of radiative forcing. Agriculture is known to be the major anthropic emitter. This work is part of the FERTECOL project and its objective is to measure the emissions of nitrous oxide by a production crop with an eddy covariance system. The measurements extent over the growth period, cover a large range of climatic conditions and capture peak events associated with fertilization. The measurements, started in April 2013, are carried at the Lonzée Terrestrial Observatory (50°33'5.83"N- 4°44'46.22"E). On this year, the crop is planted with winter wheat. A Quantum Cascade Laser Absorption Spectrometer (QCLAS, GSMA, France) is used to measure nitrous oxide as well as water vapor and carbon dioxide at a frequency of 5 hertz. The fluxes are computed using the Eddy Covariance technique adapting standards quality and corrections procedures set up for CO2 fluxes to N2O. Standard meteorological measurements are performed in parallel. The analysis will present response of the fluxes to environmental variables as well as to fertilization events during the season. [less ▲]

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See detailDrug delivery systems based on amphiphilic polyphosphate-copolymers
Vanslambrouck, Stéphanie ULg; Clement, Benoît ULg; Riva, Raphaël ULg et al

Poster (2013, September 18)

Thanks to their biocompatibility, biodegradability and their structure similar to natural biomacromoleculesn such as nucleic acids, polyphosphates (PPhos) are of prime interest as biomaterials. In ... [more ▼]

Thanks to their biocompatibility, biodegradability and their structure similar to natural biomacromoleculesn such as nucleic acids, polyphosphates (PPhos) are of prime interest as biomaterials. In contrast to poly--caprolactone and polylactides, PPhos properties and functionality are easily tuned via the nature of the pendant group of the starting cyclic monomer. For example, by varying the length of the alkyl chain the hydrophobicity of the PPhos can be adjusted. In this work, an efficient organo-catalytic system was developed to synthesize a series of amphiphilic diblock copolymers, i.e. poly(ethylene oxide)-b-polyphosphate (PEO-b-PPhos) by ring-opening polymerization of cyclic phosphates. This novel approach prevents metallic residues to polute the final product, and which is highly desirable when biomedical applications are foreseen. For drug delivery application, the micellization of these novel diblock copolymers in aqueous media was investigated, as well as, encapsulation of an hydrophobic drug. Data on, the influence of the polyphosphate nature of the polymer on drug loading will be presented. [less ▲]

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See detailAlgebrability of nowhere Gevrey differentiable functions
Esser, Céline ULg

Conference (2013, September 17)

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See detailSoluble biomarkers to evaluate chondroprotection: The Revolution is underway !
Henrotin, Yves ULg

Conference (2013, September 17)

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See detailReplication of large-scale epistasis studies: an example on ankylosing spondylitis
Bessonov, Kyrylo ULg; Van Steen, Kristel ULg

Poster (2013, September 17)

Ankylosing spondylitis (AS) is a common form of inflammatory arthritis occurring in approximately 5 out of 1,000 adults of European descent. Recently, the Australo-Anglo-American Spondyloarthritis ... [more ▼]

Ankylosing spondylitis (AS) is a common form of inflammatory arthritis occurring in approximately 5 out of 1,000 adults of European descent. Recently, the Australo-Anglo-American Spondyloarthritis Consortium and the WTCCC2 showed that polymorphisms of ERAP1 only affect AS risk in HLA-B27-positive individuals, hereby establishing an interaction between ERAP1 and HLA in the TASC, WTCCC2 and replication datasets [2,5]. We were able to confirm this interaction although using other SNPs. In this study, we use the aforementioned data from WTTCC2 on AS to address unresolved issues when performing large-scale SNP-SNP interaction studies, so as to better guarantee “stable” and “truly replicable” results. These issues are 1) the choice of variable selection method (e.g., of known loci mapping to genes part of know pathways), 2) the choice of SNPs representing a genomic region (e.g., SNPs with modest versus negligible LD between them), 3) the choice of analysis method (e.g., regression-based versus data-reduction (non-parametric) based), 4) different adjustment schemes for lower-order effects (using additive/co-dominant genetic models). We show that even modest changes in 1)-4) may give rise to quite varying epistasis findings for AS, and motivate some “optimal” choices via extensive simulation studies. In this work we rely on a minimal GWAI protocol for genome-wide epistasis detection using SNPs, as developed in our lab [6][9], using the advanced non-parametric Model-Based Multifactor Dimensionality Reduction (MB-MDR) method [1] and an adapted [*] BOolean Operation-based Screening and Testing (BOOST) algorithm [4]. [*] A BOOST [4] like implementation based on the original BOOST algorithm which accounts for missing genotypes [less ▲]

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See detailNumerical simulation of the electrical characteristics of CIGS/CdS/ZnO solar cell heterostructures
Amand, Julien ULg; Nguyen, Ngoc Duy ULg

Poster (2013, September 17)

The electrical characteristics of CIGS-based solar cell heterostructure have been simulated by numerically solving the basic semiconductor equations by means of a finite differences method based on a ... [more ▼]

The electrical characteristics of CIGS-based solar cell heterostructure have been simulated by numerically solving the basic semiconductor equations by means of a finite differences method based on a Scharfetter-Gummel discretization scheme. The electric potential, electric field, carrier concentrations, current densities and recombination rates are obtained as function of the space coordinate and the bias voltage. Starting with the analysis of a single absorber layer structure sandwiched between two metal electrodes, we subsequently studied the properties of the CIGS/ZnO pn heterojunction and the influence of the buffer layer thickness in the CIGS/CdS/ZnO on the cell electrical response. A special focus was also given to the influence of grain boundaries in the bulk of CIGS depending on the defects nature and concentration. [less ▲]

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See detailThe intra-articular injection of alginate-chitosan beads in an hydrogel prevents the development of osteoarthritis in ACLT model
Oprenyeszk, Frédéric ULg; Chausson, M; Maquet, V et al

Conference (2013, September 16)

Purpose To evaluate the effects of a new biomaterial composed of alginate-chitosan (AC) beads dispersed in a viscous thermogelling chitosan-based (H) hydrogel on the development of osteoarthritis (OA) in ... [more ▼]

Purpose To evaluate the effects of a new biomaterial composed of alginate-chitosan (AC) beads dispersed in a viscous thermogelling chitosan-based (H) hydrogel on the development of osteoarthritis (OA) in rabbit. Materials & Methods OA was surgically induced by the transection of the anterior cruciate ligament (ACLT) in rabbits. One week after surgery, animals received a single intra-articular injection (900 µl) of AC beads in H hydrogel (group I), H hydrogel alone (group II) or saline (group III). OA development was followed by X-rays. Blood samples were collected throughout the study to measure biological markers (PGE2 and CRP). Macroscopic observation and histological evaluation of articular cartilage and synovial membrane were performed 6 weeks after surgery. Results The X-rays analysis showed a significant decrease (p <0.05) of the Kellgren and Lawrence score in group I (1.5 ± 0.2) compared with group II (2.2 ± 0.5) and group III (3.0 ± 0.4). The size and the severity of the macroscopic OA cartilage lesion tended to decrease in group I compared to the other groups. The histological global score that refers to all compartments of the knee joint was significantly decreased in group I (11.0 ± 0.7) compared to group II (14.4 ± 0.6, p <0.01) and group III (14.8 ± 0.6, p <0.001). The injection of AC beads in H hydrogel also tended to reduce the synovial membrane inflammation. No significant variation of PGE2 and CRP serum levels were observed in each after 6 weeks follow-up whatever the treatment injected. Conclusion This study showed that AC beads dispersed in H hydrogel prevented OA in ACL transection rabbit model. This effect was not observed with the hydrogel alone, suggesting that AC beads play a role in joint protection. The preventive effect was observed in all joint compartments indicating a global protective effect of this new implantable biomaterial. [less ▲]

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See detailSilver nanowire network : physical properties and effects of thermal treatments
Lagrange, Mélanie; Langley, Daniel ULg; Giusti, Gael et al

Conference (2013, September 16)

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See detailHealth related guidelines for wind farms in Belgiu m
van den Berg, Frits; Passchier, Wim; Botteldooren, Dick et al

Conference (2013, September 15)

In 2011 the Belgian authorities have asked the Supe rior Health Council (SHC) to advise on the health e ffects of wind farms. A working group of experts with diff erent backgrounds was put together to ... [more ▼]

In 2011 the Belgian authorities have asked the Supe rior Health Council (SHC) to advise on the health e ffects of wind farms. A working group of experts with diff erent backgrounds was put together to assess all th e available literature. This group considered the req uest in the context of sustainable development and drafted an advice that was reviewed by two international ex perts. It is expected that the advice will be publi shed in the spring of 2013. The advice mentions direct effects of operational w ind turbines that may have negative consequences fo r the health and well-being of neighbouring people. It st resses the importance of factors such as the change in landscape, the possible intrusion on people’s attac hment to their environment and the effect of local economic benefits and costs associated with a wind energy project. Also, the perception of the future quality of life will determine the social acceptance of a w ind project by a local community. The advice gives a number of recommendations to better deal with all t hese aspects. The paper will give an overview and explanation of these recommendations. [less ▲]

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See detailRegional urban groundwater body risk assessment of contaminants using remotely sensed multi-resolution land-cover data
Batelaan, Okke; Dujardin, Juliette; Jamin, Pierre ULg et al

Conference (2013, September 15)

Contaminated sites are often the result of past relatively anarchic economical and industrial development. The last decades stakeholders are more aware of the risks posed by these sites. Within the Frac ... [more ▼]

Contaminated sites are often the result of past relatively anarchic economical and industrial development. The last decades stakeholders are more aware of the risks posed by these sites. Within the Frac-Weco project an integrated framework for the assessment, at regional scale, of the risks posed by these contaminated sites on water resources and ecosystems has been developed. The methodology is based on the calculation of contaminant fluxes reaching the receptors providing a way of estimating the level of exposure/degradation of these receptors at the groundwater body scale. The most important contamination problems at regional scale are located around old urban and industrialized areas. The land-cover distribution in these zones is of prime importance because it determines the spatial variation of groundwater recharge, which is the main vector of contaminant leaching from soil surface to groundwater. To obtain detailed information about land cover for groundwater recharge modeling, a stratified satellite image classification approach was adopted combining land-cover mapping at pixel level for the studied area as a whole with sub-pixel estimation of imperviousness within built-up zones. The obtained land-cover data is used as an input in the WetSpass model to simulate groundwater recharge at high resolution in spatially complex urban areas. In the next step the simulated groundwater recharge is used as an input in a regional scale groundwater flow and transport model simulating contaminant dispersion through the aquifer. Modeling results are further used to calculate a quality index for the whole groundwater body based on threshold values defined specifically for each contaminant. The approach proposed has been applied on the RWM073 groundwater body corresponding to the alluvial deposits of the Meuse River, Liège (Belgium). The high-resolution groundwater recharge estimations obtained by integrating remote sensing in the modeling procedure allow a better identification of the potential sources of contaminants and enable a proper quantification of total fluxes of contaminants from brownfields into the groundwater. The developed framework for regional risk assessment results in a global quality indicator for the groundwater body which can be used as input for decision-making. [less ▲]

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See detailHistoire culturelle du goût. Vers l'invention d'une gastronomie française
Von Hoffmann, Viktoria ULg

Conference (2013, September 14)

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See detailCrop association to improve biological control: case study on pea and wheat aphids
Chevalier Mendes Lopes, Thomas ULg; Bodson, Bernard ULg; Francis, Frédéric ULg

Conference (2013, September 13)

Nowadays, strategies used to control aphids in fields of pea, Pisum sativum L., and wheat, Triticum aestivum L., still rely on synthetic insecticides which have negative effects on the environment and ... [more ▼]

Nowadays, strategies used to control aphids in fields of pea, Pisum sativum L., and wheat, Triticum aestivum L., still rely on synthetic insecticides which have negative effects on the environment and human health. This research focused on the development of sustainable alternative methods, with special emphasis on cultural practices and plant management systems. Increasing the diversity within crops may have several beneficial effects on pest control, creating attractive habitats for indigenous beneficial fauna and simultaneously deterring pests – the ‘push-pull’approach. In this field study, two wheat/pea associations (mixed cropping and strip cropping) where compared to monocultures of pea and wheat. The abundance and diversity of adult aphidophagous insects (predators and parasitoids) were accessed weekly using yellow traps, while aphids were observed directly on plants. In both crops, the percentage of plants infested with aphids and density of aphid colonies were significantly higher in monocultures during periods of aphid abundance. Mixed cropping was particularly beneficial for the pea, whereas strip-cropping was more efficient for the wheat. The abundance of beneficials was significantly higher in monocultures comparing to the other treatments. Quantitative aphid-natural enemy food webs showed that the abundance of the two main ladybird species, Coccinella septempunctata L. and Propylea quatuordecimpunctata (L.), increased with the occurrence of Acyrthosiphon pisum (Harris) on pea plants. Abundance of the two main species of Syrphidae, Sphaerophoria scripta (L.) and Eupeodes corollae (F.), increased with the occurrence of Sitobion avenae (F.) and Metopolophium dirhodum (Walker) on wheat plants. This study shows that increasing diversity within crops can help lower aphid infestations. However, additional methods are needed to more efficiently attract aphidophagous beneficials and promote the natural control of aphids. [less ▲]

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See detailCongenital pseudarthrosis of the tibia: a mathematical approach
Van Schepdael, An; Carlier, Aurélie ULg; Ashbourn, Joanna et al

Conference (2013, September 13)

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See detailAditi et les naissances héroïques
Swennen, Philippe ULg

Conference (2013, September 13)

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See detailTRAPPIST (TRAnsiting Planets and PlanetesImals Small Telescope)
Jehin, Emmanuel ULg; Gillon, Michaël ULg; Opitom, Cyrielle ULg et al

in EPSC Abstract 2013 (2013, September 13), 8

TRAPPIST is a 60-cm robotic telescope that has been installed in June 2010 at the ESO La Silla Observatory [1]. Operated from Liège (Belgium) it is devoted to the detection and characterisation of ... [more ▼]

TRAPPIST is a 60-cm robotic telescope that has been installed in June 2010 at the ESO La Silla Observatory [1]. Operated from Liège (Belgium) it is devoted to the detection and characterisation of exoplanets and to the study of comets and other small bodies in the Solar System. We describe here the hardware and the goals of the project and give an overview of the comet production rates monitoring after three years of operations. [less ▲]

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See detailWhere are the politics in responsible innovation? European governance, technology assessments, and beyond
Van Oudheusden, Michiel ULg; Charlier, Nathan ULg

Conference (2013, September 13)

Responsible innovation (RI) is founded on the idea that the introduction and adoption of technology in society fails when technologies do not reflect societal needs and values. Hence, proponents of RI ... [more ▼]

Responsible innovation (RI) is founded on the idea that the introduction and adoption of technology in society fails when technologies do not reflect societal needs and values. Hence, proponents of RI solicit society’s opinions in an attempt to render technology developments and policies more socially responsive. Solicitation typically takes the form of broad consultations involving as many relevant stakeholders as possible, in ways that enhance inclusiveness, transparency, and deliberation. This paper asks how the RI concept is taken up and elaborated, based on accounts developed on the EU policy level and on a local, Flemish, technology assessment level. It finds that, notwithstanding important differences between these two deliberative frameworks, neither one leaves much room for politics, understood as the constitution and contestation of power. Rather, these frameworks largely ignore questions about the politics in deliberation (e.g. how actors craft RI through strategic use of argument and other advantage-seeking techniques), as well as the politics of deliberation (i.e. how RI privileges a process definition of democracy at the cost of participatory and representative perspectives). In addition, these frameworks forsake questions about the authoritative allocation of values (as in formalized, representative politics) and the institutional uptake of deliberative engagements more broadly. The paper’s aim is to provide a constructive criticism of the RI paradigm by rendering the above political issues explicit and proposing ways of taking them into account. [less ▲]

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See detailClass V β Tubulin during the development of the organ of Corti in rat
Renauld, Justine ULg; Thelen, Nicolas ULg; Johnen, Nicolas ULg et al

Poster (2013, September 13)

In eutherian mammals, the organ responsible for the transduction of sound waves into nerve impulses is called the organ of Corti. This structure located within the cochlea, a portion of the inner ear, is ... [more ▼]

In eutherian mammals, the organ responsible for the transduction of sound waves into nerve impulses is called the organ of Corti. This structure located within the cochlea, a portion of the inner ear, is composed by two types of cells: sensory hair cells and non-sensory supporting cells. All these cells are distributed according to a specific arrangement along the whole length of the cochlea. A feature of the organ of Corti’s supporting cell is the presence of an abundant cytoskeleton. This one is mainly composed of microtubules, structures make up by tubulin heterodimers. The heterodimers consist of one molecule of α tubulin and one molecule of β tubulin. β tubulin isotypes are highly conserved in evolution and differ by only a few amino acid residues, implying that the isotypes may have functional significance. Organ of Corti’s supporting cells are constituted by class V β-tubulin, a minor mammalian tubulin (Bhattacharya et al., 2008). Moreover, their microtubules are formed by 15 protofilaments instead of the canonical 13, a unique fact among vertebrates (Banerjee et al., 2008). Such a configuration of protofilaments has been observed in C. elegans’ neurons which are responsible for the mechanosensory sense of touch (Bounoutas et al., 2009). It was also shown that these 15 protofilaments microtubules were essential to the proper functioning of these mechanosensory neurons (Bounoutas et al., 2009). Here we present the spatiotemporal localization of class V β-tubulin during the development of the organ of Corti in rats from embryonic day 18 (E18) until P25 (25th postnatal day). For this purpose, we have used immunolabelings on cryosections of whole cochlea. Our preliminary results demonstrate that class V β-tubulin has a unique distribution in the cochlea, being restricted to supporting cells, especially in pillar cells. [less ▲]

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See detailAN IMMUNOLOGICAL METHOD TO COMBINE THE MEASUREMENT OF ACTIVE AND TOTAL HUMAN MYELOPEROXIDASE ON THE SAME SAMPLE FROM A COMPLEX MEDIUM
Franck, Thierry ULg; MINGUET, Grégory ULg; Mossay, Pierre et al

Conference (2013, September 12)

Active neutrophil myeloperoxidase (MPO) is a powerful producer of oxidant molecules in acute or chronic inflammation, and it is essential to measure its activity in biological samples. We combined two ... [more ▼]

Active neutrophil myeloperoxidase (MPO) is a powerful producer of oxidant molecules in acute or chronic inflammation, and it is essential to measure its activity in biological samples. We combined two immunological techniques, the SIEFED (specific immunologic extraction followed by enzymatic detection) and an ELISA, to measure the active and total contents of human MPO on the same sample and with the same calibration curve, to define an accurate ratio between the active and total enzyme. After the extraction of MPO from aqueous or biological samples by immobilized anti-MPO antibodies followed by a washing to eliminate unbound material, the active and the total contents of the enzyme were sequentially measured without interferences (patent: EP2017351-B1, 2010). Compared to a classical sandwich ELISA, there is one additional step corresponding to the in situ measurement of MPO activity, but this step does not affect the following measurement of the total MPO content. After validation, the combined technique was applied to a whole blood model of in vitro stimulation with phorbol-myristate-acetate (PMA), cytochalasin B/N-formyl-methionyl-leucyl-phenyl-alanine (CB/fMLP) or lipopolysaccharide/ tumor necrosis factor-alpha (LPS/TNF-α) (n=9). The active/total MPO ratio in whole blood reached 0.267±0.126 for non-stimulated condition and was significantly (p<0.05) higher for PMA (0.360±0.106), CB/fMLP (0.380±0.113) and LPS/TNF-α (0.432±0.124) stimulated conditions. These different ratios highlight the real oxidant potential of MPO, which depends on the stimulating conditions, witness of what could happen in pathological situations with diagnostic purpose. The combined SIEFED/ELISA method also appeared as a powerful tool to screen potential inhibitors that could interact directly with the enzyme, either on its active site or on another key position. [less ▲]

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See detailTRAPPIST monitoring of comet C/2012 F6 (Lemmon)
Opitom, Cyrielle ULg; Jehin, Emmanuel ULg; Manfroid, Jean ULg et al

Poster (2013, September 12)

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See detailCould bonobos, Pan paniscus, influence forest re(colonization) in a forest-savana mosaic?
Trolliet, Franck ULg; Serckx, Adeline ULg; Huynen, Marie-Claude ULg et al

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013, September 12)

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See detailStudy of the forbidden oxygen lines in comets at different heliocentric and nucleocentric distances
Decock, Alice ULg; Jehin, Emmanuel ULg; Rousselot, Philippe et al

in EPSC Abstract 2013 (2013, September 12), 8

Oxygen is an important element in the chemistry of the Solar System objects given its abundance and its presence in many molecules including H2O, which constitutes 80% of cometary ices. The analysis of ... [more ▼]

Oxygen is an important element in the chemistry of the Solar System objects given its abundance and its presence in many molecules including H2O, which constitutes 80% of cometary ices. The analysis of oxygen atoms in comets can provide information not only on the comets themselves but also on our Solar System. These atoms have been analyzed using the three forbidden oxygen lines [OI] observed in emission in the optical region at 5577 Å (the green line), 6300 Å and 6364 Å (the red lines) [1]. These lines are difficult to analyze because their detection requires high spectral and spatial resolutions. The oxygen analysis is interesting because it allows the determination of its parent molecules. [less ▲]

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See detailTRAPPIST monitoring of comet C/2012 F6 (Lemmon)
Opitom, Cyrielle ULg; Jehin, Emmanuel ULg; Manfroid, Jean ULg et al

in EPSC Abstract 2013 (2013, September 12), 8

Comet C/2012 F6 is a long-period comet that reached perihelion on March 23, 2012. The unexpected brightness of this comet since December 2012 allowed us to obtain narrowband photometry and to study its ... [more ▼]

Comet C/2012 F6 is a long-period comet that reached perihelion on March 23, 2012. The unexpected brightness of this comet since December 2012 allowed us to obtain narrowband photometry and to study its chemical composition as well as its rotation. [less ▲]

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