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See detail"Madame Bovary c'est moi"
Cormann, Grégory ULg

Conference (2016, October 29)

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See detailThe ‘cyanobiome’ of Svalbard, High Arctic
Stelmach Pessi, Igor ULg; Laughinghouse, H Dail; Velazquez, David et al

Poster (2016, October 28)

Over the last decades, the Arctic has experienced a warming trend that is nearly twice as high as the global average, a phenomenon known as ‘Arctic amplification’. The impact of warmer temperatures on ... [more ▼]

Over the last decades, the Arctic has experienced a warming trend that is nearly twice as high as the global average, a phenomenon known as ‘Arctic amplification’. The impact of warmer temperatures on Arctic ecosystems is still unclear. Cyanobacteria are the key primary producers in freshwater and terrestrial Arctic ecosystems, where they are the driver for numerous ecological functions. For a better understanding of the impacts of climate change on Arctic ecosystems, baseline knowledge on cyanobacterial diversity and distribution is crucial. Here we investigate, for the first time, the biogeographic patterns of cyanobacterial communities across Svalbard, using 454 pyrosequencing of partial 16S rRNA gene sequences. Samples were taken from distinct ecosystems and biogeographic zones. We also compare the studied communities with similar Antarctic communities. [less ▲]

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See detailDeriving cultural heritage values: the use of social media
Ginzarly, Manal ULg; Teller, Jacques ULg

in Old and New Media for the Image of the Landscape (2016, October 28)

Nel 2011 l’UNESCO ha adottato la Raccomandazione sul Paesaggio Storico Urbano che mira al riconoscimento e all'identificazione della stratificazione e dell'interconnessione dei valori - naturali e ... [more ▼]

Nel 2011 l’UNESCO ha adottato la Raccomandazione sul Paesaggio Storico Urbano che mira al riconoscimento e all'identificazione della stratificazione e dell'interconnessione dei valori - naturali e culturali, materiali e immateriali, internazionali e locali – riscontrabili in qualsiasi città storica, concepita come un “patrimonio vivente” delle comunità. In tale visione il patrimonio culturale urbano è un elemento riconosciuto non solo dagli esperti, ma dalle intere società che ne valutano gli elementi identitari mirando a conservarli per le generazioni future. La Raccomandazione, in particolare, sostiene che per l'interpretazione e la conservazione del patrimonio culturale si può beneficiare di metodi di valutazione tradizionali e di metodi innovativi basati su dati geo-localizzati e sui dati digitali dei social media, come tweets geo-localizzati, impronte digitali e foto su Flickr. Il presente contributo illustra una metodologia basata sull’analisi delle immagini su Flickr. Dai risultati ottenuti si è evinto che proprio l’indagine dei social media può contribuire ad una comprensione significativa dei valori culturali del contesto urbano, fornendo così la possibilità di una migliore integrazione dei valori socio-culturali riconosciuti dalla collettività nei processi di conservazione e di pianificazione urbana. [less ▲]

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See detailLes masques de Sartre: de l'anthropologie à Frantz Fanon et Hubert Lyautey
Cormann, Grégory ULg

Conference (2016, October 28)

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See detailThe BCCM/ULC collection to conserve the biodiversity and explore the applied potential of Polar cyanobacteria
Becker, Pierre; SZTERNFELD, P; ANDJELKOVIC, M et al

Poster (2016, October 28)

In the Polar Regions, Cyanobacteria represent key primary producers and are the main drivers of the food webs in a wide range of aquatic to terrestrial habitats. For example, they build benthic microbial ... [more ▼]

In the Polar Regions, Cyanobacteria represent key primary producers and are the main drivers of the food webs in a wide range of aquatic to terrestrial habitats. For example, they build benthic microbial mats in lakes and soil crusts in terrestrial biotopes. They may present interesting features to survive freeze/thaw cycles, seasonally contrasted light intensities, high UV radiations, dessication and other stresses. The BCCM/ULC public collection funded by the Belgian Science Policy Office since 2011 aims to gather a representative portion of the polar cyanobacterial diversity with different ecological origins (limnetic mats, soil crusts, cryoconites, endoliths…). It makes it available for researchers to study the taxonomy, evolution, adaptations to harsh environmental conditions, and genomic make-up. It presently includes 226 cyanobacterial strains, with 119 being of Antarctic origin (catalogue: http://bccm.belspo.be/catalogues/ulc-catalogue-search). An ISO 9001 certificate was obtained for the public deposition and distribution of strains, as part of the multi-site certification for the BCCM consortium. The morphological identification shows that the strains belong to the orders Synechococcales, Oscillatoriales, Pleurocapsales, Chroococcidiopsidales and Nostocales. The 16S rRNA and ITS sequences of the strains are being characterized. Our results show that the Antarctic strains are positioned into 25 OTUs (sequences with > 97,5% 16S rRNA similarity), and thus, represent a quite large diversity. In addition, cyanobacteria are known to produce a wide range of secondary metabolites (e.g. alkaloids, cyclic and linear peptides, polyketides) with bioactive potential. Among these bioactive metabolites, some display antibiotic, anticancer or antifungal effects. In collaboration with the BCCM/IHEM collection of biomedical fungi, a screening of cyanobacterial strains from BCCM/ULC was performed in order to discover potential new antifungal drugs. The analysis of a first set of methanol extracts from 15 different strains put in evidence the antifungal activity of a Phormidium priestleyi isolate. The latter remains active up to 0.5% (v/v) of fungal culture and was able to inhibit the growth of various fungal species among Candida, Cryptococcus, Aspergillus, and Penicillium. The raw extract was subjected to HPLC and a fraction containing the active molecule was obtained. This molecule appeared to be a thermostable hydrophobic compound. Moreover, in vitro toxicological analyses suggest that the compound has a general cytotoxic effect that could be inhibited by the mammalian metabolism. Further analyses are needed to identify the molecule and to determine if it could be a candidate for a new antifungal drug. In summary, the BCCM/ULC public collection serves as a Biological Resource Centre to conserve ex situ and document the biodiversity of polar cyanobacteria, as well as a repository for discovery of novel bioactive compounds. [less ▲]

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See detailQuelques réflexions à propos du régime de (dé)fiscalisation des revenus des PME dans le système fiscal belge
Bourgeois, Marc ULg

in Aydogdu, Roman (Ed.) Les petites et moyennes entreprises dans le droit des affaires (2016, October 27)

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See detailCase report: Ovarian fibroma in a mare – Hormonal considerations
Ponthier, Jérôme ULg; Salciccia, Alexandra ULg; Parrilla Hernandez, Sonia ULg et al

in Reproduction in Domestic Animals (2016, October 27), 51(supplement 2), 132

This report shows that, as in humans, AMH as well as steroids productions are low in case of ovarian fibroma, thus preserving normal cyclicity.

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See detailOccurrence and significance of minute palynomorphs of marine and non - marine origin in the Middle Ordovician from Saudi Arabia
Le Hérissé, A.; Guidat, C.; Not, F. et al

Conference (2016, October 27)

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See detailEcoNum, a research unit devoted to marine environment monitoring
Richir, Jonathan ULg; Batigny, Antoine; Georges, Nadège et al

Conference (2016, October 27)

The monitoring of coastal environments remains a research domain of great interest and concern. Coastal ecosystems are threatened by natural and human-induced stressors and are, as transitional ... [more ▼]

The monitoring of coastal environments remains a research domain of great interest and concern. Coastal ecosystems are threatened by natural and human-induced stressors and are, as transitional environments, particularly sensitive to disturbances. EcoNum first research thematic revolves around hermatypic corals, calcifying organisms, and their adaptation potentials to environmental changes including by using original and patented chemostats. The studied organisms are grown and maintained in artificial mesocosms that simulate environmental conditions of a natural system. This infrastructure allows to perform long-term experiments, giving time to organisms to adapt to the tested conditions (e.g., increased temperature or lowered pH). Longer-term studies have demonstrated that many organisms are more resistant to environmental stressors than previously observed on the short-term. EcoNum also studies coastal plankton abundance and diversity. Plankton is particularly sensitive to physicochemical changes of water bodies. The classification and the enumeration of planktonic organisms require specialized tools in order to analyse time series of multiple samples. EcoNum has developed a software for the semi-automatic classification of planktonic organisms called Zoo/PhytoImage. This software has been used to study a 10-year time series of coastal Mediterranean zooplankton samples. The concomitant analysis of environmental parameters registered at high frequency with specific statistical tools such as the R package pastecs allows to understand the processes governing the changes observed in plankton assemblages. The use and the development of statistical tools in R (e.g., Zoo/Phytoimage, pastecs) is a priority of EcoNum to favour open access knowledge and reproductive sciences. EcoNum research topics also focus on coastal ecotoxicology. Chemicals, including trace elements, remain contaminants of concern, mainly in coastal environments that are the final sink of inland pollution sources. The chemical integrity of coastal ecosystems thus has to be accurately monitored. The partitioning of chemicals between their dissolved, particulate and sedimentary phases does not provide information on their bioavailability. EcoNum thus monitors coastal waters using bioindicator species such as seagrasses, mussels or sand worms. A global map of the contamination of the Mediterranean by trace elements has been drawn using seagrasses has bioindicator species. EcoNum also studies trace element ecology and toxicology. For instance, it has demonstrated the toxicity of copper on the coral Seriatopora hystrix and it's symbiont's photosynthetic processes, or its bioaccumulation and basipetal translocation towards rhizomes in the seagrass Posidonia oceanica as reserve nutrient for subsequent leaf growth. Finally, coastal vegetated systems are potential carbon thinks (or sources) in the global carbon cycle. Therefore, EcoNum studies the primary productivity of seagrass meadows, from the individual to the community, with measuring techniques as diverse as PAM-fluorometry or biomass production determination. To conclude, EcoNum is a research unit devoted to marine environment monitoring. It develops research thematics on major coastal communities such as coral reefs, seagrass beds or plankton assemblages and studies their natural dynamics and the effects of stressors on their global functioning. [less ▲]

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See detailLa place de la coopération sud -sud dans les stratégies d'action des pays émergents : Acteurs et Enjeux des relations entre l'Afrique et l'Amérique latine
Mvengou Cruzmerino, Martine Colette ULg

Conference (2016, October 27)

This comunication deals with the use of South-South Cooperation as strategic tool for emergent, and its place in the external policies of Brazil, Southa africa and Venezuela. This work focuses also on the ... [more ▼]

This comunication deals with the use of South-South Cooperation as strategic tool for emergent, and its place in the external policies of Brazil, Southa africa and Venezuela. This work focuses also on the interregional relations between Latin American and Africa and the impact and opportunities of this kind of interregional south south cooperation. [less ▲]

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See detailSilurian palynomorphs from the Precordillera basin, western Argentina: biostratigraphy and diversity trends
Garcia Muro, V.J.; Rubinstein, C.V.; Steemans, Philippe ULg

Poster (2016, October 27)

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See detailLIFE CYCLE IN PRACTICE – FEEDBACK FROM A SME'S COACH
Groslambert, Sylvie ULg; Léonard, Angélique ULg

Conference (2016, October 27)

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See detailLes 10 ans d’Envol à l’école Saint-Pierre : La musique et le conte au centre des apprentissages et du vivre ensemble dans les classes
Gavray, Claire ULg

Conference (2016, October 27)

historique du projet, évaluation des apports et perspectives

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See detailPlant functional trait diversity in wildflower strips: the key to promote pollinators in agricultural landscapes?
Uyttenbroeck, Roel ULg; Piqueray, Julien; Monty, Arnaud ULg

Conference (2016, October 27)

Creating wildflower strips is often suggested as a tool to support pollinator diversity in agricultural landscapes and to promote crop pollination service. The choice of the plant species to sow in flower ... [more ▼]

Creating wildflower strips is often suggested as a tool to support pollinator diversity in agricultural landscapes and to promote crop pollination service. The choice of the plant species to sow in flower strips can influence the effectivity of the strips in supporting pollinators. While it has already been shown that increasing plant species diversity is beneficial for ecosystem services, it is often suggested that plant functional traits and functional trait diversity are the key for this relationship. We created a replicated field experiment with different levels of plant functional diversity in wildflower strips in Belgium to test the effect on the flower-visiting pollinator community. We sampled plant-pollinator interaction networks during 2 years and assessed how the plant functional diversity affected the network structure. Plant functional diversity did not have a clear effect on visiting pollinator species richness, however a different interaction pattern was observed with different functional diversity level. Pollinators in wildflower strips with higher functional diversity had less overlap in their ecological niche, while network stability and robustness for secondary extinctions were not affected. We discuss implications for wildflower strip design. [less ▲]

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See detailINFLUENCE OF THE DATASETS CHOICE ON LCA RESULTS: EXAMPLE OF GLUCOSE PRODUCTION
Gerbinet, Saïcha ULg; Belboom, Sandra ULg; Léonard, Angélique ULg

Conference (2016, October 27)

The aim of this study is to have a good understanding of the environmental impact of glucose production to be able to study material produce from glucose. Glucose is general-ly produced from corn or wheat ... [more ▼]

The aim of this study is to have a good understanding of the environmental impact of glucose production to be able to study material produce from glucose. Glucose is general-ly produced from corn or wheat. Since agricultural processes are known to be difficult to evaluate by LCA, the results obtained with two different LCA databases, Gabi and EcoIn-vent, are compared in this work. The production of glucose from raw materials can be divided in two steps: the agricul-tural step allowing the plant production, and the conversion step including the extraction of the starch from the plant and its hydrolysis into glucose. Preliminary results underline the high impact of the agricultural step, so a special attention has been paid to these data. Specific Belgian data collected by the Walloon Agricultural Research Centre (CRA-W) (2014) [1] have been used as primary data (yield, amount of fertilizers, etc.), either using EcoInvent or Gabi datasets background data to model fertilizers, diesel consumption, etc. A third model was built using only data available in Ecoinvent for corn and wheat cultures. For the conversion step, literature data have been used along with some industrial data. As few studies are available in the literature concerning starch hydrolysis, the focus has been placed on data validation (mass balance checks, cross-reference information, etc.). Based on these multiple sources, it is possible to compare the LCA results for the pro-duction of 1 kg of glucose for three different cases, summarized in the following table. Table 1: Summary of modelled cases Agricultural step Conversion steps Primary data Dataset Primary data Dataset Case 1 Belgian GaBi Literature + Industry GaBi Case 2 Belgian Ecoinvent Literature + Industry Ecoinvent Case 2 Ecoinvent Literature + Industry Ecoinvent The results obtained using these three models will be presented, at both the inventory and impact assessment steps. They show significant differences and highlight the need to understand in depth the involved assumptions when developing the datasets, in addition to the ones adopted for the inventory. These differences in results lead to higher uncer-tainties, allowing only to have a range of possible values as a result. We make the choice to only communicate this range of value and not an absolute value when communicating the results of this study but this leads to some disadvantages such as difficulties in com-parison, etc. [less ▲]

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See detailPalynology and palaeogeography of the middle Přídolí from Saudi Arabia
Steemans, Philippe ULg; Breuer, P.; Al-Hajri, S. et al

Conference (2016, October 27)

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See detailBounding surface plasticity model for natural clays
Ahayan, Sanae ULg; Yin, Zhen-Yu; Kotronis, Panagiotis et al

Conference (2016, October 26)

Natural soft clay exhibits a considerable degree of anisotropy as a result of its past sedimentation and consolidation history. It also tends to have significant inter-particle bonding, which affects its ... [more ▼]

Natural soft clay exhibits a considerable degree of anisotropy as a result of its past sedimentation and consolidation history. It also tends to have significant inter-particle bonding, which affects its mechanical behavior. The natural structure of in-situ soils makes their behavior different from that of a reconstituted material. In fact, most clays lose a proportion of their strength when remoulded. Various authors proposed anisotropic elastoplastic soil models allowing the yield surface to rotate with the stress history. These models have a “rotational hardening law" which relates the change of the inclination of the yield surface to the current soil state and to the increments of the plastic volumetric and/or shear strain, [Sekiguchi and Otha (1977)], [Hashiguchi and Chen (1998)], [Wheeller et al (2003)]… Other authors combine the plastic anisotropy with destructuration effects observed in soft sensitive soils by assuming that the size and /or the position of the center of the yield surface depends on the amount of the structural soil degradation. These models use an additional isotropic hardening law that relates the size and/or the position of the yield surface of the intact sample to that of the reconstituted one [Nova et al (2003)]. The previous models provide little or no flexibility when it comes to describe the change of the plastic modulus with the loading direction as they are unable to produce a smooth degradation of the stiffness, being single yield surface models. A way to improve this behavior is to introduce the “bounding surface plasticity” theory, initially developed by Dafalias [Dafalias and Herrmann 1986]. Unlike a single yield surface model, the bounding surface theory allows a smooth transition of stresses within and on the bounding surface. The mean feature of this concept is that the actual stress is mapped to the imaginary stress on the bounding surface. The distance between the real and imaginary stress, which is called the “ function distance ”, is used to specify the plastic modulus. This work presents a bounding surface plasticity model for natural and structured clays based on the critical state theory. A novel rotational hardening rule for clays is presented, and a hardening function distance is introduced to describe the evolution of the bounding surface. Validation of the model is provided by drained and undrained tests of Scottish and Finnish intact and reconstituted clays [Kastunnen 2008]. Finally, finite element simulations of a foundation considering the formulated constitutive law are presented. [less ▲]

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See detailSpecific interests in Autism with versus without speech onset delay : the importance of perceptually versus thematically organized interests
Chiodo, Liliane ULg; Eusèbe, Sandrine; Majerus, Steve ULg et al

Poster (2016, October 25)

To explore whether autistic adults with versus without speech delay also differ in the perceptual vs thematic nature of their specific interests.

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See detailHeta-Uma: manga on the other side of the mirror
Dejasse, Erwin ULg

Conference (2016, October 25)

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See detailLa importación literaria a finales del siglo XIX en Colombia: el caso de José Asunción Silva
Mogollon Zapata, Juan Manuel ULg

Conference (2016, October 25)

The analysis of the of Silva’s collection of works places us in quite a disconcerting, yet no less encouraging, position, when re-assessing the different forms of importing literary movements. On one hand ... [more ▼]

The analysis of the of Silva’s collection of works places us in quite a disconcerting, yet no less encouraging, position, when re-assessing the different forms of importing literary movements. On one hand, the image attributed to Silva both by his contemporaries and his successors is that of the leading figure in the assimilation and absorption of the literary European movements that would give rise to modernism. On the other hand, the absence of public visibility for Silva’s works, be it through texts or paratexts, let us in a difficult situation to prove the poet’s will to position himself as the one who introduced the new literary movement to Colombia. If we accept from the outset, as we will in this article, that the Colombian poet possessed an obstinate determination to appropriate and assimilate the European literary movements that give rise to modernism, then we must entertain the possibility that Silva’s literary transfer took place through media other than books, journals or magazines. Our hypothesis is that by focusing on the acts of reading and poise, the literary coterie became the ideal platform for the Colombian writer to adopt and propagate the image of the decadent writer, which would become the embodiment of the aesthetic ideals of modern literature. [less ▲]

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See detailAffect as well as object properties impact measurement estimations.
Dumitru, Magdalena ULg

Conference (2016, October 25)

The probability of perceiving objects in a group as being similar to each other is a negative exponential function of the distance between them in a psychological space (Shepard 1987). Here I summarize ... [more ▼]

The probability of perceiving objects in a group as being similar to each other is a negative exponential function of the distance between them in a psychological space (Shepard 1987). Here I summarize results from recent experimental studies showing that the psychological distance and thereby the similarity between objects of the same category depends on object properties such as size, frequency, and manipulability. For example, people judged elephants to be more different from each other than ants are. Further results show that irrelevant object properties evoked by digit-word expressions modulate numerosity estimations. For example, people judged “8 elephants” to be more numerous than “8 ants”. Taken together, these findings demonstrate that individuals need not directly perceive specific object properties in order to develop numerosity estimation biases (cf. Binet 1890) but promptly and unduly take into account irrelevant object properties when the objects are being merely mentioned, suggesting that words can instantly access rich mental representations that subsequently affect measurement estimations. Additional experimental findings suggest that emotional states can also impact measurement estimations. [less ▲]

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See detailDes expériences vécues aux savoirs d'expérience : (in)former la santé et la maladie dans des associations de patients en Belgique francophone
Duysens, Fanny ULg

Conference (2016, October 25)

Le diagnostic médical d'une pathologie est un événement significatif dans les parcours de vie des patients et de leurs proches. Il vient catégoriser des symptômes, participer aux processus de (re ... [more ▼]

Le diagnostic médical d'une pathologie est un événement significatif dans les parcours de vie des patients et de leurs proches. Il vient catégoriser des symptômes, participer aux processus de (re)construction de soi, et induire des attitudes et comportements en vue d'intervenir activement sur les événements. Notamment, il correspond pour certains au moment de leur engagement au sein d'une association concernée par la pathologie ou le syndrome diagnostiqué en question. De telles associations de patients s'impliquent souvent dans diverses activités de production, de mobilisation et de circulation de connaissances sur les conditions et leurs causes. Ces modes d'activisme dits "basés sur la connaissance" (evidence-based activism) se caractérisent par une articulation étroite entre des connaissances issues d'expertise biomédicale et des connaissances expérientielles, issues des expériences vécues au quotidien par les patients et leurs proches, dont ils revendiquent la légitimité. S'inscrivant à la croisée des Science and Technology Studies et de l'anthropologie de la santé et de la maladie, la présente communication vise à explorer les dynamiques de cette articulation à partir d'une ethnographie multi-site menée auprès d'associations belges francophones concernées par des pathologies ou syndromes génétiques. Plus particulièrement, la communication s'intéresse à un projet d'information et de sensibilisation autour du trouble du spectre autistique (TSA) qui est développé par un groupe de parents concernés. Le TSA y est défini comme une condition complexe et multidimensionnelle, aux causes incertaines et controversées mais dont ils revendiquent la part déterminante de la génétique. Comment des "connaissances expérientielles" sont-elles produites, validées et mises en circulation dans le cadre de telles activités ? Au-delà de la simple information, les observations montrent qu'elles comportent des enjeux identitaires importants. [less ▲]

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See detailA benchmark for urban flood modelling
Arrault, Anaïs; Finaud-Guyot, Pascal; Archambeau, Pierre ULg et al

Poster (2016, October 25)

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See detailTopos de Grothendieck et fonctions holomorphes tempérées
Dubussy, Christophe ULg

Conference (2016, October 24)

Dans les années 60, Grothendieck révolutionna la géométrie algébrique en introduisant le concept de topos. Faisant face à des situations où la notion d'ouvert était trop restrictive pour comprendre les ... [more ▼]

Dans les années 60, Grothendieck révolutionna la géométrie algébrique en introduisant le concept de topos. Faisant face à des situations où la notion d'ouvert était trop restrictive pour comprendre les phénomènes géométriques sous-jacents, il définit une nouvelle notion de topologie dans le langage de la théorie des catégories. Très utilisée pour résoudre des problèmes de géométrie et d'analyse contemporains, cette notion a aussi de nombreuses applications surprenantes en logique (théorie intuitionniste, équivalence de Morita, etc ...). Dans ce séminaire je proposerai une application de la théorie des topos de Grothendieck pour étudier les fonctions et les distributions tempérées. En effet, ces objets ne forment un faisceau que sur une topologie de Grothendieck particulière (la topologie sous-analytique), qui n'est pas une topologie au sens usuel du terme. Je montrerai alors, de manière abstraite, comment définir un faisceau de fonctions holomorphes tempérées qui a joué un rôle crucial dans la démonstration de la correspondance de Riemann-Hilbert (généralisation du 21ème problème d'Hilbert). En particulier, ce nouveau faisceau fournira une nouvelle définition, presque purement algébrique, des distributions de Schwartz. [less ▲]

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See detailThe recent increase of methane from 10 years of NDACC ground-based FTIR observations
Bader, Whitney ULg

Conference (2016, October 24)

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See detailUn cadrage général pour l'éducation aux médias?
Hamers, Jérémy ULg

Conference (2016, October 24)

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See detailAlgunas consideraciones metodológicas sobre la teoría de las transferencias
Mogollon Zapata, Juan Manuel ULg

Conference (2016, October 24)

Las siguientes consideraciones metodológicas surgen esencialmente de la confrontación de la teoría de las transferencias con mi corpus actual de trabajo, esto es, con las modalidades de importación ... [more ▼]

Las siguientes consideraciones metodológicas surgen esencialmente de la confrontación de la teoría de las transferencias con mi corpus actual de trabajo, esto es, con las modalidades de importación literaria durante el modernismo, época que, como todos sabemos, constituyó un momento de apertura privilegiado para la apropiación y asimilación de las producciones culturales extranjeras. Los escollos metodológicos encontrados a medida que avanzábamos en la problematización de nuestro corpus sirvieron pues de estímulo para integrar y transponer algunos conceptos y herramientas teóricas tomados principalmente de la teoría de los campos de Pierre Bourdieu, del análisis del discurso a la manera de Dominique Maingueneau y de la poética histórica de los soportes tal y como ha sido desarrollada en Francia por Alain Vaillant y Marie-Ève Thérenty. Es a partir de dicho diálogo que podemos hoy afinar ciertos conceptos y herramientas teóricas indispensables para repensar algunos puntos ciegos de la teoría de las transferencias. [less ▲]

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See detailThermochemical conversion of sugar industry by-products to biofuel
Nicodème, Thibault ULg; Jacquet, Nicolas ULg; Richel, Aurore ULg

Poster (2016, October 24)

Poster concernant la conversion des co-produits de l'industrie sucrière en biocarburants via la voie thermochimique. Description des procédés tels que la gazéification, Fischer-Trospch, la pyrolyse.

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See detailFolie et Corps chez Hegel
Rizzo, Rémy ULg

Conference (2016, October 24)

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See detailImpacts de champignons entomopathogènes sur la biologie et le comportement de la punaise diabolique (Hemiptera, Pentatomidae)
Fingu Mabola, Junior Corneille ULg; Serteyn, Laurent ULg; Bawin, Thomas ULg et al

Poster (2016, October 22)

Halyomorpha halys Stål, la punaise diabolique, est une espèce invasive préoccupante en provenance d’Asie de l’Est. En moins de 15 années, elle a colonisé près de l’ensemble des Etats-Unis d’Amérique ... [more ▼]

Halyomorpha halys Stål, la punaise diabolique, est une espèce invasive préoccupante en provenance d’Asie de l’Est. En moins de 15 années, elle a colonisé près de l’ensemble des Etats-Unis d’Amérique, occasionnant des pertes de rendement considérables dans les vergers et les cultures en champs ainsi que des nuisances dans les habitations durant l’hiver. La punaise diabolique a été recensée en Suisse en 2007, et il est à craindre qu’elle colonise la presque totalité de l’Europe d’ici 2020. Cette étude a pour objectif de prévenir l’installation de la punaise diabolique dans les pays européens en se focalisant sur le contrôle biologique. Des scientifiques américains ont développé une stratégie « attirer et tuer » basée sur la phéromone d’agrégation de la punaise diabolique et des pesticides. D’autres ont montré l’efficacité d’un champignon pathogène d’insectes (Beauveria bassiana strain GHA. Afin d’établir un contrôle rapide du ravageur en Europe, compatible avec l’agriculture biologique, une idée serait de combiner l’effet attractif de la phéromone d’agrégation et l’application de spores de B. bassiana. Dans cette étude, l’impact du champignon sur la mortalité de l’insecte et son autodissémination sont évalués. [less ▲]

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See detailLa pubalgie - Rééducation post-chirurgicale
Delvaux, François ULg; DANIEL, Christophe ULg; NAMUROIS, Marie-Hélène ULg et al

Conference (2016, October 22)

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See detailConclusions
Dozo, Björn-Olav ULg; Philippette, Thibault; Servais, Olivier

Conference (2016, October 22)

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See detailModéliser pour comprendre les phénomènes
Karous, Hamad ULg; Nihant, Brigitte ULg; Leyh, Bernard ULg

Conference (2016, October 22)

Il existe actuellement un consensus sur le fait que les scientifiques ne décrivent pas la réalité telle qu’elle est dans toute sa complexité mais qu’ils en construisent des représentations qui leur ... [more ▼]

Il existe actuellement un consensus sur le fait que les scientifiques ne décrivent pas la réalité telle qu’elle est dans toute sa complexité mais qu’ils en construisent des représentations qui leur permettent de l’expliquer partiellement et de la maîtriser, partiellement également. De telles représentations sont généralement appelées des modèles et le processus de leur construction est la modélisation. Les référentiels et programmes de sciences insistent de plus en plus, dans un souci d’authenticité épistémologique, sur la nécessité de confronter les élèves aux modèles établis et à leur élaboration, afin qu’ils se constituent une vision aussi fidèle que possible de l’entreprise scientifique. Le concept de modèle possède des composantes multiples et il n’est pas aisé d’en donner une définition compacte, complète et définitive. On pourrait tenter de dire, en bref, que modéliser, c’est simplifier délibérément pour pouvoir expliquer et agir efficacement. On peut envisager différents types de modèles qui ne s’excluent pas mutuellement. On les rencontrera dans les différentes activités expérimentales que nous proposons. (i) On peut tout d’abord modéliser une situation expérimentale complexe (une pile commerciale ou un accumulateur, par exemple) par une autre situation apparentée mais plus simple et dont on contrôle mieux les paramètres, afin de mettre leur influence en lumière. Diverses expériences sur les piles (de Daniell, entre autres) illustrent cet aspect. Les expériences proposées sur la diffusion entrent également dans cette catégorie. (ii) En chimie, le principe explicatif fondamental consiste à fonder les observations macroscopiques sur des processus décrits au niveau sub-microscopique (atomes, molécules, ions, électrons). Cette représentation sub-microscopique peut être schématique et/ou symbolique. Pour plusieurs des expériences proposées, on demande de représenter schématiquement les mouvements des particules concernées. On demande aussi de traduire le phénomène en un langage symbolique, l’écriture de la réaction chimique. Ici aussi, il s’agit d’une modélisation : quand on écrit HCl(aq), par exemple, on remplace une situation complexe et relativement mal définie – des ions H3O+ et des ions Cl- hydratés avec éventuellement plusieurs couches d’hydratation – par une écriture compacte qui représente de manière conventionnelle l’essentiel de l’information dont on a besoin dans un but déterminé (un titrage, par exemple). [less ▲]

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See detailComportement du puceron du pois face aux volatiles du basilic.
Yarou, Boni Barthélémy ULg; Boullis, Antoine ULg; Verheggen, François ULg et al

Poster (2016, October 22)

Les pucerons font partie des insectes qui causent des dégâts d’importances économiques sur une grande diversité de plantes cultivées. Les insecticides de synthèse généralement utilisés pour les contrôler ... [more ▼]

Les pucerons font partie des insectes qui causent des dégâts d’importances économiques sur une grande diversité de plantes cultivées. Les insecticides de synthèse généralement utilisés pour les contrôler montrent de plus en plus leurs limites (résistance), et sont néfastes pour l’homme et l’environnement. Dans la recherche de méthodes de lutte alternatives, le comportement de choix d’Acyrthosiphon pisum Harris (Homoptera : Aphididae) exposé à des sources d’odeurs de plant de fèves (Vicia fabae L.) et du basilic européen (Ocimum basilicum L.) à l’aide d’un olfactomètre en Y a été étudié. Les observations de cette expérience montrent que les pucerons se dirigent préférentiellement vers la source d’odeurs de fève et y passent plus de temps. Ce résultat montre que les volatiles du basilic ont un effet répulsif sur les pucerons du pois. D’autres tests seront évalués sur des espèces de pucerons plutôt généralistes afin de valider l’effet répulsif du basilic sur les pucerons. [less ▲]

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Peer Reviewed
See detailMallarmé et le “motif commun”
Durand, Pascal ULg

Conference (2016, October 21)

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See detailDevelopment of an analytical method for the simultaneous measurement of 10 biogenic amines in food
Douny, Caroline ULg; Benmedjadi, Soumaya; Blaszczyk, Marie et al

Poster (2016, October 21)

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See detailPhysiological Responses to training and competition in 1 to 4 star eventing horses
Kirsch, Katharina ULg; Düe, M.; Holzhausen, H. et al

Poster (2016, October 21)

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See detailSurgical treatment of mucometra in an Alpine Goat.
Casalta, Hélène ULg; Knapp, Emilie ULg; Evrard, Laurence ULg et al

Poster (2016, October 21)

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See detailSea ice: Source or sink of nitrous oxide?
Kotovitch, Marie ULg; Fripiat, François ULg; Moreau, Sebastien et al

Conference (2016, October 21)

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See detailReported post-operative analgesic administration to non-human primates: 2010 - 2015
Bertrand, Henri ULg; Flecknell, Paul; Brady, James et al

Poster (2016, October 21)

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See detailImplication of ADAM10 protease in malignant mesothelioma
Sepult, Christelle ULg

Conference (2016, October 21)

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See detailA time series study during spring transition in the fast ice at Davis station, Antarctica: preliminary resul
Deman, F.; Roukaerts, A.; Delille, Bruno ULg et al

Conference (2016, October 21)

While representing less than 5% of the total ice cover around Antarctica, fast ice is nevertheless an important habitat with highest biomass and production occurring in the bottom (Archer et al., 1996 ... [more ▼]

While representing less than 5% of the total ice cover around Antarctica, fast ice is nevertheless an important habitat with highest biomass and production occurring in the bottom (Archer et al., 1996). Sea--‐ice algae are playing a key role in structuring the ecosystem, as they are an essential food source for krill. With the annual melting of the sea ice there is a strong release of nutrients and algae to the water, possibly fertilizing and/or seeding algae the underlying water column. A time series was sampled during the Austral spring of 2015 (Oct. 27th – Dec. 11th), in the vicinity of Davis station (68°35’ S, 77°58’ E, Prydz Bay, Antarctica). Fast ice, snow cover and underlying water column were sampled with focus on the nitrogen and carbon cycle and the pivotal role of sea--‐ice algae for higher tropic levels. Different parameters such as nutrients, particulate matter (PM) and isotopic signatures for nitrate, ammonium and PM will be measured. Primary production and uptake rates for different nitrogen substrates were also measured using in--‐situ stable isotope incubation experiments to study the change in algae growth rates. That campaign was performed in close relation with colleagues from the Institute of Marine and Antarctic Studies (Hobart, Australia) to link our findings with the availability of trace metals such as iron. Temperature profiles in the ice showed a clear change halfway the sampling campaign with increasing temperatures, likely accompanied by an increase in permeability throughout the ice. Results show a large accumulation of biomass in the bottom few 5 cm (particulate organic carbon reaching up to 1300 μmol l‐1). Preliminary data also shows a large accumulation of nitrate at the bottom with concentrations exceeding those in the underlying water. Preliminary results will be presented and discussed. [less ▲]

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See detailHamlet revisité
Delville, Michel ULg

Conference (2016, October 21)

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See detailLung resident eosinophils represent a distinct cell subset with homeostatic functions
Mesnil, Claire ULg; Raulier, Stéfanie ULg; Paulissen, Geneviève et al

Conference (2016, October 21)

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See detailMetabolites from media supplemented with 3’-sialyllactose and fermented by bifidobacteria have an antivirulent effect against intestinal pathogens
Bondue, Pauline ULg; Daube, Georges ULg; Delcenserie, Véronique ULg

Poster (2016, October 21)

Complex oligosaccharides from human milk (HMO) promote growth of Bifidobacterium bifidum. Oligosaccharides from cow milk (BMO), similar to HMO, are mainly represented in colostrum by 3’-sialyllactose ... [more ▼]

Complex oligosaccharides from human milk (HMO) promote growth of Bifidobacterium bifidum. Oligosaccharides from cow milk (BMO), similar to HMO, are mainly represented in colostrum by 3’-sialyllactose (3’SL). Bifidobacterium crudilactis, a species from bovine origin and encoding for β galactosidases and α-glucosidases, could be able to metabolise them. Also, fermentation products could have antivirulent activity against intestinal pathogens. This study focused on capacity of bifidobacteria to metabolise 3’SL and on potential antivirulent effect of cell-free spent media (CFSM) against pathogenic bacteria. B. bifidum BBA1 and B. crudilactis FR/62/B/3 isolated respectively from breastfed children feces and cow raw milk cheese were grown on media supplemented with 3’SL as sole source of carbon. Next, CFSM effects were tested against virulence gene expression using ler and hilA promoter activity of luminescent constructs of Escherichia coli 0157:H7 ATCC 43888 and Salmonella Typhimurium SA 941256, respectively. The effect was confirmed on wild type strains of E. coli O157:H7 ATCC 43890 and S. Typhimurium ATCC 14028 using RT-qPCR. Both strains were able to grow in presence of 3’SL. CFSM resulted in under-expression of hilA and ler genes for the luminescent constructs and in under-expression of ler (ratios of -15.4 and -8.1) and qseA (ratios of -2.1 and -3.1) genes for the wild type strain of E. coli O157:H7. No effect was observed with S. Typhimurium. Little is known about CFSM metabolites and they have to be isolated and identified. The potential synbiotic effect between 3’SL and bifidobacteria will be tested using the Shime®, a human gastrointestinal model. [less ▲]

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See detailLa sécurité sociale face au droit européen de la concurrence
Detienne, Quentin ULg

Conference (2016, October 21)

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See detailLa pubalgie du sportif - Actualités thérapeutiques conservatrices
Kaux, Jean-François ULg

Conference (2016, October 21)

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See detailGaseous Micro-Emboli Removal during priming procedure using pulsatile flow with 4 different adult oxygenators with integrated arterial filter and open reservoir.
HELLA, Dominique ULg

Conference (2016, October 21)

4 oxygenators were tested during priming procedures with pulsatile flow. 2 showed better results.A prospective and randomized study begon in June 2016, including 200 patients. We hope with the same ... [more ▼]

4 oxygenators were tested during priming procedures with pulsatile flow. 2 showed better results.A prospective and randomized study begon in June 2016, including 200 patients. We hope with the same comparison to show interesting results. 4 oxygénateurs adultes testés durant la phase de priming utilisant le débit pulsé. 2 se révèlent supérieurs. Une étude prospective randomisée incluant 200 patients a démarré depuis juin 2016 afin de réaliser la même comparaison en clinique; nous espérons en extraire des résultats intéressants. [less ▲]

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See detailLa mise en scène du télétravail : le contrôle managérial au cœur d’un paradoxe entre hypervisibilité et invisibilité
Fox, Fanny ULg; Pichault, François ULg

Conference (2016, October 21)

Le présent article s’intéresse à la reconfiguration du contrôle managérial face à une des évolutions actuelles des formes de travail, à savoir le travail à distance. Après avoir circonscrit ce concept et ... [more ▼]

Le présent article s’intéresse à la reconfiguration du contrôle managérial face à une des évolutions actuelles des formes de travail, à savoir le travail à distance. Après avoir circonscrit ce concept et à partir d’une étude empirique menée au sein d’un groupe international du secteur des télécommunications, cette thématique particulière est abordée à l’aune de la sociologie de Goffman. Cette dernière s’avère singulièrement riche pour appréhender les changements, y compris digitaux, qui prennent place à l’heure actuelle dans les organisations. L’apport goffmanien est double : le propos de l’auteur constitue, d’une part, les bases de la méthodologie ethnographique de recueil des données élaborée et, d’autre part, l’éclairage théorique choisi pour discuter les résultats empiriques. Il apparaît ainsi que le contrôle managérial du travail à distance donne naissance à des situations paradoxales au sein desquelles s’opposent l’invisibilité engendrée par l’absence intra muros et l’hypervisibilité mise en place lorsque les personnes sont présentes dans les établissements physiques de l’entreprise, d’une part, et à travers les outils technologiques, d’autre part. La recommandation classique de la littérature prônant le passage à une direction par objectifs s’avère insuffisante pour répondre à l’enjeu du contrôle managérial. Les conclusions de cette recherche suggèrent davantage une hybridation réfléchie des modes de contrôle articulés autour d’une relation de confiance. [less ▲]

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See detailInbreeding and genomic runs of homozygosity in Vietnamese local chickens
Moyse, Evelyne ULg; Nguyen Van, Duy; Vu Dinh, Ton et al

Poster (2016, October 21)

Most researches on genetic variety evaluation in Vietnamese local chicken breeds have been based up to now on microsatellite markers (Cuc et al., 2011; Pham et al., 2013). Thanks to the genotyping of ~580 ... [more ▼]

Most researches on genetic variety evaluation in Vietnamese local chicken breeds have been based up to now on microsatellite markers (Cuc et al., 2011; Pham et al., 2013). Thanks to the genotyping of ~580,000 SNPs on 95 chickens, this study aimed to assess the genetic diversity in four Vietnamese local breeds (Mia, Mong, Ho and Dong Tao). Inbreeding was examined through the detection of runs of homozygosity (ROH; Curik et al., 2014). The ROHs are long stretches of homozygous genome that are likely to reflect autozygosity. Given that Ho chickens have a small effective population size, more inbreeding and consequently longer ROHs are expected. Conversely, Mia chickens, with a larger effective population size should show less consanguinity and shorter ROHs. As expected, Mia chickens led to less observed homozygosity and less ROHs than the three other breeds. Moreover, when ROHs were subdivided in different lengths, the proportion of individuals having at least one R OH longer than 5Mb was significantly higher in Ho (63%) than in Mia chickens (33%). Given that very long ROHs are particularly associated with recent inbreeding, it seems that many Ho chickens have consanguineous parents. However, no significant difference was observed between the four breed concerning the total length of long ROHs (> 5Mb). In conclusion, the analysis of ROHs reported less consanguinity in Mia than in Ho chickens. In each breed, some individuals are found more consanguineous than expected. This study also confirms that ROHs are a useful tool in inbreeding research. [less ▲]

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See detailLa quête d’Isis ou la confirmation de Dieu : l’interpretatio Kircheriana
Winand, Jean ULg

Conference (2016, October 21)

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See detailThe genesis of a negative agentive nominalizer. The journey of jwtj between Old Egyptian and Coptic
Grossman, Eitan; Polis, Stéphane ULg

Conference (2016, October 21)

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See detailHighly productive, yet heterotrophic, and still pumping CO2 from the atmosphere: A land fast ice paradigm?
Delille, Bruno ULg; Van der Linden, Fanny ULg; Conte, L et al

Conference (2016, October 21)

The YROSIAE (Year Round survey of Ocean-Sea Ice-Air Exchanges) survey aimed to carry out a year-round survey of land-fast sea ice focusing on the study of sea ice physics and biogeochemistry. Ice cores ... [more ▼]

The YROSIAE (Year Round survey of Ocean-Sea Ice-Air Exchanges) survey aimed to carry out a year-round survey of land-fast sea ice focusing on the study of sea ice physics and biogeochemistry. Ice cores, sea water, brines material were collected at regular intervals about 1 km off cape Evans in McMurdo Sound, Antarctica, from November 2011 to December 2011 and from September 2012 to December 2012. Samples were processed to characterize both the vertical distribution and temporal changes of climate gases (CO2, DMS, CH4, N2O), CO2-related parameters (ice-air CO2 fluxes, dissolved inorganic carbon, total alkalinity and CaCO3 amount), physical parameters (salinity, temperature, and ice texture), biogeochemical parameters (macro-nutrients, particulate and dissolved organic carbon, δ13C, δ30Si and δ15N) and biological parameters (chlorophyll a, primary production within sea ice derived from O2:Ar and O2:N ratios…). Very high chlorophyll a abundance was observed at the bottom of the ice, a common feature of land fast ice in McMurdo Sound. During spring, chlorophyll a exhibited a significant increase suggesting high primary production. . However, at the same time, nutrients at the bottom of the ice increased significantly suggesting high remineralization and heterotrophy. In the middle of the ice column, evolution of dissolved inorganic carbon shown a succession of autotrophic and heterotrophic phases. However, the overall increase of DIC suggests that the ice interior was rather heterotroph. This was consistent with the increase in nutrients observed at the bottom of the ice. Such sea ice system should expel CO2. Yet, strong under saturation in CO2 in surface ice, and negative air-ice CO2 fluxes suggested that sea ice was taking up CO2 from the atmosphere. Meanwhile, measurements of N2O within the sea ice suggest that the ice was releasing N2O to the atmosphere as a result of high nitrification. On the whole land fast sea ice in McMurdo Sound appears as a puzzling ecosystem. It is able to support elevated growth of autotrophic organisms, but appears to be heterotrophic, yet pumping CO2 to the atmosphere but releasing other greenhouse gases. [less ▲]

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See detailParentalité et précarité : Le lien au cœur des pratiques et des recherches
Halin, Stéphanie; Fohn, Bruno; Glowacz, Fabienne ULg

Conference (2016, October 20)

La parentalité est un concept difficile à définir car il s’inscrit à la fois "dans le champ social, juridique et psychologique" [1]. De nos jours, le « devenir parent » est décrit comme un processus ... [more ▼]

La parentalité est un concept difficile à définir car il s’inscrit à la fois "dans le champ social, juridique et psychologique" [1]. De nos jours, le « devenir parent » est décrit comme un processus dynamique, qui débute dès le désir d’enfant, et qui s’accompagne de remaniements psychiques importants chez les deux parents. Depuis plusieurs années, des études se sont intéressées à l’impact de la précarité sur la sphère familiale. Il est aujourd’hui reconnu que la précarité psychosociale impacte toutes les dimensions du développement de l’enfant et plusieurs dimensions de la parentalité (sensibilité parentale, disponibilité émotionnelle, pratiques éducatives, …). La précarité est définie comme « l’absence d’une ou plusieurs des sécurités, notamment celle de l’emploi, permettant aux personnes et aux familles d’assumer leurs obligations professionnelles, familiales et sociales, et de jouir de leurs droits fondamentaux » [2]. Selon Furtos, à la précarité économique s’ajoute la précarité psychosociale et, parfois, un syndrome d’auto exclusion sociale. Selon lui, « d’un côté, l’environnement est excluant, tandis que de l’autre côté le mot « auto » renvoie à la part du sujet : tout en subissant une situation d’exclusion, le sujet a la capacité d’exercer sur lui-même une activité pour s’exclure de la situation, pour ne pas la souffrir, transformant ainsi le subir en agir » [3]. Ce public est caractérisé par une problématique du lien. Entrer en relation, s’investir dans un suivi, maintenir une continuité du lien sont autant de défis pour les parents en syndrome d’autoexclusion sociale. Parvenir à les rejoindre nécessite donc de développer des structures flexibles et créatives, tant en ce qui concerne le suivi psychosocial que la recherche. Au travers de différentes recherches-action auprès de ces familles, nous avons été confrontés à la nécessité de développer un processus de recherche basée sur le lien pour accéder tant à l’évaluation de pratiques d’intervention et à l’évaluation du vécu de ces parents. Nos travaux ont montré combien le lien occupe une place centrale dans la prise en charge et dans la recherche avec des bénéficiaires en grande précarité psychosociale. Références [1] Doumont, D., & Renard, F. (2004). Parentalité: nouveau concept, nouveaux enjeux? Document publié en ligne, Université Catholique de Louvain, pp. 1-18, https://www.uclouvain.be/cps/ucl/doc/reso/documents/Dos31.pdf [2] Kettani, M., & Zaouche-Gaudron, C. (2012). Sentiment de compétence paternelle et adaptation socioaffective des enfants de deux à six ans en contexte de précarité socioéconomique. Pratiques psychologiques, 18, pp. 75–88. Doi:10.1016/j.prps.2011.02.001 [3] Furtos, J. (2011). La précarité et ses effets sur la santé mentale. Le Carnet PSY, 156 (7), pp.29-34. Doi :10.3917/lcp.156.0029 [less ▲]

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See detailExistera-t-il encore un CPAS dans dix ans ?
Behrendt, Christian ULg

Conference (2016, October 20)

Exposé donné dans le cadre du 8e congrès de la Fédération Wallonne des Assistants Sociaux des CPAS (FéWASC), Campus universitaire de Liège (Sart Tilman), Faculté de Droit, 20 octobre 2016.

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See detailLes environnements flexibles sont-ils un terrain d'émancipation pour le travailleur? Le cas d'une entreprise publique belge.
Fauconneau-Dufresne, Sophie ULg

Conference (2016, October 20)

Les environnements flexibles sont en vogue. Présentés dans la littérature managériale comme un terrain d'émancipation pour les travailleurs, gages d'un accroissement de leur autonomie et de leur liberté ... [more ▼]

Les environnements flexibles sont en vogue. Présentés dans la littérature managériale comme un terrain d'émancipation pour les travailleurs, gages d'un accroissement de leur autonomie et de leur liberté, ils font désormais partie intégrante des projets de modernisation. Constatant un état des lieux plus alarmiste sur cette thématique dans la littérature académique, nous mettons en question le caractère réellement émancipatoire de ce type d'espace. Par une recherche empirique, conduite dans une entreprise publique belge, nous observerons une réalité plus nuancée. Quand ils ne font pas l'objet de réformes profondes de l'organisation du travail dès le tout début du processus de changement, ce type d'agencement est susceptible de se faire au détriment des travailleurs. [less ▲]

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See detailThe Middle Ages: A New Age for the Reception of the Gods of Egypt
Veymiers, Richard ULg

Conference (2016, October 20)

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See detailWhat’s Avant about the Poetic Neo-Avant-Garde ?
Delville, Michel ULg

Conference (2016, October 20)

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See detailDevelopment and evaluation of real-time PCR targets for the detection of insect in feed
Gerard, Amaury ULg; Debode, Frédéric; Marien, Aline et al

Poster (2016, October 19)

Insects are rich in proteins and could be an alternative source of proteins to feed animals. Numerous companies started the production of insects at small or larger scale as feed for chicken and fish ... [more ▼]

Insects are rich in proteins and could be an alternative source of proteins to feed animals. Numerous companies started the production of insects at small or larger scale as feed for chicken and fish. Most of the business models for feed production are based on the black soldier fly (Hermetia illucens) or the mealworm (Tenebrio molitor). In Europe, these novel feed are not yet authorized and products are commercialized outside Europe or eventually used as pet food (e.g. wild birds). For further authorization in Europe, many questions must be clarified concerning the presence of antinutritional compounds, the risk associated to pathogens, to residues (pesticides, antibiotics, heavy metals) and to allergens. To authorize such products on the market, methods to detect if a product really contains insects and to authenticate insect products are also mandatory. European Commission Regulation No 51/2013 named the Polymerase Chain Reaction as a reference method to determine the constituents of animal origin in feed. Targets focused on insects (target common to all insects) and targets specific to particular insect species are required. PCR methods are developed at CRA-W in this way. Among the methods developed, three of them already gave interesting results. The first one (81 bp) is specific to all insects excepting individuals from the Diptera order. The two others (94 bp and 114 bp) are specific to Tenebrio molitor. The specificity of the targets was tested against 45 insect species and on 10 commercial insect-based feed products (real-processed feed material samples). The sensitivity of the method was assessed through the AFNOR XP V03-020-2 standard approach using the LOD6 method. The three methods reached the recommended performance criteria (LOD≤ 20 copies). [less ▲]

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See detailL’identité narrative au prisme du roman contemporain : d’un nouveau rapport à la fiction dans le récit de soi
Huppe, Justine ULg

Conference (2016, October 19)

Dans le champ intellectuel contemporain, la pensée de Paul Ricœur semble avoir pleinement intégré l’outillage conceptuel requis pour penser les identités et modes de subjectivation. Contre les conceptions ... [more ▼]

Dans le champ intellectuel contemporain, la pensée de Paul Ricœur semble avoir pleinement intégré l’outillage conceptuel requis pour penser les identités et modes de subjectivation. Contre les conceptions du texte comme espace formel autorégulé, Ricœur a décrit le récit comme un dispositif cognitif fondamental, offrant aux individus et aux collectivités des modes de subjectivation et des prises sur le monde. Cette approche constitue un bénéfice disciplinaire non- négligeable pour les sciences humaines. Cette actualité de Ricœur peut sembler paradoxale. Certes, le concept de refiguration permet de penser les effets du récit dans le monde, à une époque où la diffusion massive d’information nécessite de capter l’attention par des récits efficaces (storytelling en politique, publicité, management, infotainment). Par contre, le concept d’identité narrative ne semble pas pouvoir se justifier de la même actualité. En effet, quoi de plus opposé à nos expériences démultipliées que cette forme narrative qui devrait les ordonner dans un récit unique ? Quoi de plus hétérogène que le vécu de l’individu contemporain, sans cesse sommé de s’adapter à de nouveaux rôles et de nouveaux projets ? Dans le cadre de cette communication, notre objectif sera d’évaluer la pertinence du concept d’identité narrative pour penser les modes de subjectivation individuelle, par le prisme de plusieurs romans contemporains (Farah, Delaume, Mérot, Minard, de Toledo, Vasset). Comment le récit de vie littéraire développe-t-il des formes qui puissent répondre aux expériences fragmentaires des sujets ? Ces formes renouvellent-elles l’usage de la narration et/ou de la fiction ? [less ▲]

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See detailFaire famille aujourd'hui : expériences de personnes gays, lesbiennes et trans
Scali, Thérèse ULg

Conference (2016, October 19)

Les multiples systèmes, formes, catégories et pratiques de la parenté ont retenu l’attention des anthropologues comme une dimension centrale des façons dont les individus et les groupes humains conçoivent ... [more ▼]

Les multiples systèmes, formes, catégories et pratiques de la parenté ont retenu l’attention des anthropologues comme une dimension centrale des façons dont les individus et les groupes humains conçoivent et vivent leurs rapports à eux-mêmes, aux autres, aux sociétés et au monde qui les entoure. Dans différents contextes et périodes historiques, des évolutions – tant démographiques, politiques, socio-culturelles, économiques, juridiques, scientifiques, médicales, ou encore relatives aux âges ou aux genres – ont contribué à sa (re)définition constante. Force est de constater que les innovations récentes concernant, entre autres, les technologies de procréation médicalement assistée et de gestation pour autrui, ou les débats autour du « mariage pour tous » et de l’adoption par des couples du même sexe, ont parfois été interprétés en termes de profondes ruptures par rapport à des conceptions plus « traditionnelles » de la parenté, ce qui leur confère un certain caractère inédit et polémique. D’un point de vue anthropologique, ces reconfigurations de la parenté témoignent de différentes modalités d’articulation entre le social, le culturel et le biologique, faits de société et faits de nature, construit et inné, dans la définition de la parenté. Cela amène à repenser la parenté dans toutes ses dimensions, du public à l’intime. Partant de l’anthropologie, et afin d’élargir le champ des réflexions empiriques, théoriques et épistémologiques, ce colloque invite à croiser les perspectives sur les (re)configurations contemporaines de la parenté dans les sciences humaines et sociales en privilégiant les approches ethnographiques. Il comprend deux axes principaux mais non exclusifs. Le premier axe entend appréhender les manières dont la question des (re)configurations contemporaines de la parenté est posée dans différents espaces publics et intimes. Le second axe ouvre quant à lui un débat épistémologique sur les regards croisés et comparatifs entre divers contextes, thématiques ou disciplines en invitant à analyser les enjeux, apports et limites issus de tels travaux de recherche. [less ▲]

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See detailImpact of skimming and microfiltration processes on equol concentration in milk
Daems, Frédéric ULg; Ninane, Véronique; Romnee, Jean-Michel et al

Poster (2016, October 19)

Equol is a microbial metabolite of isoflavones that could be used as therapeutic agent against several diseases and cancers. Cow's milk could be a potential source of equol in the human diet, but more ... [more ▼]

Equol is a microbial metabolite of isoflavones that could be used as therapeutic agent against several diseases and cancers. Cow's milk could be a potential source of equol in the human diet, but more studies are needed on the changes in equol concentration during the technological processing of milk and dairy products. This first exploratory study sought to assess the impact of industrial skimming and microfiltration processes on equol concentration in conventional cow's milk. The milk samples used in this study came from bulk cow’s milk collected in Wallonia (Belgium), by a local dairy and processed in a local cheese factory. Six random sampling were conducted during spring and, for each of them, samples from raw, skimmed and microfiltered milk were analyzed. Equol was present in all samples at a concentration of between 3.2 and 10.3 µg.L-1. A Wilcoxon's signed rank test was then performed on the difference of data, having raw milk as reference, irrespective of the collection date. The results showed that the skimming process slightly increased the equol concentration in milk and therefore that equol had no or little affinity with the lipid milk fraction. The results also showed that, with the microfiltration process, a small proportion of equol was retained. Equol concentration has returned to the same level as that found in raw milk. This might be because of a chemical affinity either with bigger molecules that are physically retained or through direct interaction with the membrane. This scoping study paves the way for more extensive studies on the interaction between equol and other components of the milk. [less ▲]

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See detailEnzensberger et l'institution littéraire
Glorie, Caroline ULg

Conference (2016, October 19)

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See detailCritique de la compilation. Hans Magnus Enzensberger et les nouveaux médias.
Hamers, Jérémy ULg

Conference (2016, October 19)

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See detailTowards precision beta-decay measurements with laser-cooled argon-35
Lenaers, Florence ULg; Glover, Rohan ULg; Bastin, Thierry ULg

Poster (2016, October 18)

Laser cooling and trapping techniques enjoy a solid reputation as powerful and elegant providers of well-localized, backing-free sources. Not only does this hold true within the atomic physics and quantum ... [more ▼]

Laser cooling and trapping techniques enjoy a solid reputation as powerful and elegant providers of well-localized, backing-free sources. Not only does this hold true within the atomic physics and quantum optics communities, but also beyond. Most notably, these techniques have recently joined the toolbox of low-energy, high-precision tests of the Standard Model. Our work with argon falls within the subset of nuclear beta decay studies, which have historically played a key role in establishing and testing our understanding of weak-interaction physics. In this framework, precision measurements of the beta asymmetry correlation parameter in the beta decay of Ar-35 have been identified as one promising probe for physics beyond the Standard Model. Our current work focuses on the development of a test magneto-optical trap (MOT) setup for Ar-40 as a preliminary step towards cooling and trapping Ar-35 atoms. In particular, much effort is being put into optimizing the efficiency of our source apparatus, which is crucial to achieving high enough statistics in the final trap. We present the current status of the experimental realization of our setup. Measuring the beta asymmetry correlation parameter requires highly spin-polarized samples. Therefore, in parallel to our experimental work, we are numerically investigating methods for generating, controlling and precisely measuring the degree of spin polarization of a sample of Ar-35 atoms. We also aim at being able to quickly switch between a polarized and a non-polarized sample so as to better understand systematic effects. We report on the progress of our theoretical modeling. [less ▲]

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See detailMobility of 137Cs, 10Be and 210Pb in soil as a function of the soil texture, organic matter content and pH
de Tombeur, Félix ULg; Cornu, Sophie; Bourlès, Didier et al

Poster (2016, October 18)

Vertical matter transfer processes (bioturbation and <2μm translocation) in soils and their dynamics are up to now poorly constrained although they are responsible for the temporal evolution of the ... [more ▼]

Vertical matter transfer processes (bioturbation and <2μm translocation) in soils and their dynamics are up to now poorly constrained although they are responsible for the temporal evolution of the ecosystem services. In order to better constrain and quantify these processes, a kinetic quantification of the involved transfers based on vertical profiles of 210Pb (xs), 10Be and 137Cs has been developed for Luvisols in which soluble transfers could be neglected. The range of applicability of this type of approach was nevertheless not tested. In this work, we analyzed 210Pb (xs), 10Be and 137Cs in soils exhibiting gradients of organic matter, pH and < 2 μm fraction (Podzol, Andosol Ferralsol, Leptosol). Acidic soils and large organic matter contents were considered. The depth distribution of the studied isotopes was then interpreted as a function of the organic matter content, the soil pH and its < 2 μm fraction. This demonstrates that 10Be and 137Cs losses occur under soluble form in the Podzol, especially under forest, more acid, for the latter. Soluble 10Be transfers were also identified in the Andosol when they were considered as negligible in the Leptosol. For 210Pb (xs), soluble transfers are also probable for soils with pH less than 5.5 (Andosol and Ferralsol) and strong affinity for organic matter has been demonstrated. Thus, under acidic conditions and low < 2 μm fraction, soluble transfer cannot neglected anymore. [less ▲]

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See detailA one year survey of seagrass primary productivity using the diving-PAM technique
Richir, Jonathan ULg; Abadie, Arnaud; Grosjean, Philippe et al

Poster (2016, October 18)

Marine magnoliophytes are major primary producers in coastal benthic habitats worldwide. They play a crucial role in the global carbon cycle (one of the more efficient blue carbon wells). Hence, it is ... [more ▼]

Marine magnoliophytes are major primary producers in coastal benthic habitats worldwide. They play a crucial role in the global carbon cycle (one of the more efficient blue carbon wells). Hence, it is necessary to characterise the eco-systemic services seagrass meadows provide. Posidonia oceanica (L.) Delile, the main Mediterranean seagrass species, has high foliar and belowground biomass production. Several methods have been used so far to measure its primary production (e.g., using incubation bells, optodes, biomass and elementary content measurements). A less used method relies on chlorophyll fluorescence measurements through the Pulse Amplitude Modulated (PAM) fluorometry method (Diving - PAM). In the framework of the STARECAPMED project, this study aimed to determine weekly to bimonthly over a one-year period the photosynthetic responses (Yield, relative Electron Transfer Rate, Rapid Light Curve) of P. oceanica. The survey was performed at 10m depth in a pristine meadow (Calvi, Corsica, France). To obtain reliable and comparable data, the protocol was standardized: measurements were performed on the convex middle part of the third leaf, at zenith, during shiny and calm weather days. Results showed that the plant displayed a well-marked seasonality. The mean ETR (μmol e- m-2 s-1 ) of the plant ranged from 2.17 in winter to 21.9 in summer and was linearly correlated throughout the year with the in situ irradiance (PAR irradiance taken perpendicularly to the surface, in the average leaf orientation). The ETR plateaus of the RLCs, ranging from 10.9 to 35.0, and their corresponding maximum PAR intensities evolved similarly. These results demonstrated both the adaptation and the seasonal plasticity of the meadow’s photosynthetic system. Overall the non-destructive PAM technique is a powerful and cost-effective tool to assess the primary productivity of seagrass meadows where other techniques (e.g. optodes) cannot be used and when direct sampling (e.g. biomass measurements) is not allowed. [less ▲]

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See detailAccurate drift time determination by traveling wave ion mobility spectrometry: The concept of the diffusion calibration
Kune, Christopher ULg; Far, Johann ULg; De Pauw, Edwin ULg

Conference (2016, October 18)

Ion mobility spectrometry (IMS) is a gas phase separation technique which relies on differences in the collisional cross section (CCS) of ions. Ionic clouds of unresolved conformers overlapped if the CCS ... [more ▼]

Ion mobility spectrometry (IMS) is a gas phase separation technique which relies on differences in the collisional cross section (CCS) of ions. Ionic clouds of unresolved conformers overlapped if the CCS difference is below the instrumental resolution expressed as Ω/ΔΩ. The experimental arrival time distribution (ATD) peak is then a superimposition of the various contributions weighted by their relative intensities. We have developed a strategy for accurate drift time determination using traveling wave ion mobility spectrometry (TWIMS) of poorly and unresolved conformers. This method implements through a calibration procedure the link between the peak full width at half maximum (FWHM) and the drift time of model compounds for wide range of settings for wave heights and velocities. We modified a Gaussian equation which achieves the deconvolution of ATD peaks where the FWHM is fixed according to our calibration procedure. The new fitting Gaussian equation only depends on two parameters: The apex of the peak (A) and the mean drift time value (µ). The standard deviation parameter (correlated to FWHM) becomes a function of the drift time. This correlation function between µ and FWHM is obtained using the TWIMS calibration procedure which determines the maximum instrumental ion beam diffusion using ionic compounds which are detected as single conformers in the gas phase. This deconvolution process has been used to highlight the presence of poorly resolved conformers for couples of crown ethers and peptides leading to CCS determination in better agreement with quantum chemistry predictions. [less ▲]

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See detailDry powder of budesonide/hydroxypropyl-beta-cyclodextrin complex for inhalation as a new potential antiasthmatic treatment
Bigazzi, William ULg; Dufour, Gilles; Mingeot-Leclercq, Marie-Paule et al

Conference (2016, October 17)

Asthma is a respiratory disease characterized by chronic airway inflammation which can lead, if not correctly managed, to tissue remodeling associated with an irreversible decline in lung function ... [more ▼]

Asthma is a respiratory disease characterized by chronic airway inflammation which can lead, if not correctly managed, to tissue remodeling associated with an irreversible decline in lung function. Hypersensitivity of the respiratory tract to non-specific stimuli, which causes triggering of asthma attacks, is also observed. Despite medical advances, asthma remains an important socio-economic and public health concern since this condition affects 300 million people and causes more than 300 000 deaths worldwide every year. Furthermore its annual cost is estimated at over 30 billion euros in Europe. These issues can be partially linked to an inadequate control of asthma due to undesirable effects of existing medication such as corticosteroids. Hence, the development of new medications with improved effectiveness and reduced adverse effects could allow a better management of the disease. It has been recently discovered that inhaled solution of hydroxylpropyl-beta-cyclodextrin (HPBCD) is able to reduce allergen-induced bronchoconstriction in asthmatic patients, with no toxicity observed in healthy patients further to administration. Based on these results, our project seeks to develop new antiasthmatic medication containing an association of HPBCD and budesonide, a widely used corticosteroid in long-term treatment of asthma. Thus, we investigated complexation between the two molecules. Interestingly, it was observed that when budesonide is complexed with HPBCD, its permeability across a Calu-3 cell layer is reduced. Several experiments in mouse models confirmed that HPBCD acts as a sustained delivery system which progressively releases budesonide into the lung parenchyma, leading to a prolonged anti-inflammatory effect. Due to high Peclet number of HPBCD, the spray dried complex exhibited wrinkled particles whose interest in dry powder for inhalation is well known. Thanks to its anti-inflammatory effect and its sustained release potential, HPBCD could significantly reduce corticosteroids needed doses for management of asthma. However, a clinical study has to be performed to determine the optimal budesonide/HPBCD ratio and the minimal effective dose of complex. Further investigations are also needed to exploit the potential of spray dried HPBCD and develop a powder for inhalation by particle engineering. [less ▲]

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See detailDiversity, dynamics and trophic ecology of animal communities associated to Posidonia oceanica (L.) Delile macrophytodetrital accumulation: synthesis of a ten year study
Lepoint, Gilles ULg; Borges, Alberto ULg; Champenois, Willy ULg et al

Poster (2016, October 17)

In the Mediterranean, Neptune grass Posidonia oceanica, produces a huge quantity of detrital biomass. These macrophytodetritus may accumulate in shallow waters, forming litter accumulations colonised by ... [more ▼]

In the Mediterranean, Neptune grass Posidonia oceanica, produces a huge quantity of detrital biomass. These macrophytodetritus may accumulate in shallow waters, forming litter accumulations colonised by abundant, yet understudied, animal communities. These accumulations are especially foraged by juvenile and adult fishes. Here, we aim to synthesize results obtained over the last ten years regarding diversity, dynamics and trophic ecology of associated meio- and macrofauna. Accumulations are found throughout the year but important seasonal and short-term variability in composition, quantity and physico-chemical parameters inside the accumulation is observed. Accumulations are dominated by respiration (litter degradation), however, primary production occurs at exposed surfaces (epiphytic production). Meio- and macrofauna have distinct traits in comparison to adjacent habitats (seagrass meadows or epilithic algae communities). A physico-chemical gradient occurs inside accumulations which partially defines assemblage composition and distribution. Meiofauna, in particular harpacticoid copepods, is diverse, abundant and composed of species from seagrass meadows, water column and sediment. In contrast, macrofaunal assemblages are simplified compared to the ones occurring in the seagrass meadows and are dominated by amphipods. Litter accumulations display a lower macrofaunal diversity than do seagrass meadows, but a higher abundance and animal biomass. Meio- and macrofauna show a high trophic diversity, dominated by ingestion and assimilation of epiphytes (macroalgae and, probably, detrivorous microbiota). Moreover, direct or indirect assimilation of carbon originating from seagrass detritus is demonstrated for many species. Although diverse trophic niches were observed, the assemblage showed a simplified trophic web structure compared to the seagrass meadows. Detritivorous organisms dominate this assemblage and are more abundant in the litter than in the living meadows. Consequently, according to its abundance and the fact it consumes directly and indirectly seagrass material, fauna associated to litter accumulation may play a significant role in the degradation and transfer to higher trophic level of detrital seagrass carbon. [less ▲]

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See detailLe rôle de la compréhension de la notion de modèle dans la vision des futurs enseignants des sciences de la structure atomique
Karous, Hamad ULg; Nihant, Brigitte ULg; Leyh, Bernard ULg

Conference (2016, October 16)

Atomic theory is a key concept in science education. However, it was found that students often have difficulties in learning the fundamental notions of this theory. These difficulties reveal themselves in ... [more ▼]

Atomic theory is a key concept in science education. However, it was found that students often have difficulties in learning the fundamental notions of this theory. These difficulties reveal themselves in the expression of some preconceptions which tend to persist over time and thus may occur up to the higher education level. The goal of our study is to highlight some difficulties related to the notions of models and modelling notions and to illustrate the causes of appearance of such preconceptions. To do this, two questionnaires were submitted to future sciences teachers (chemistry, biology and physics) who did a training at the University of Belgium in 2014-2015 and in 2015-2016 (40> participants). The first questionnaire deals with the modelling concept and process while the second one is about the atomic model diagrams which illustrate many textbooks. Identifying the nature of the models and their construction may lead to misconceptions while acquiring basic scientific knowledge. [less ▲]

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See detailSartre et Merleau-Ponty : les matérialités de la politique
Caeymaex, Florence ULg

Conference (2016, October 15)

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See detailUne hypokaliémie à Liège
VALDES SOCIN, Hernan Gonzalo ULg; EMONTS, Patrick ULg; HAMOIR, Etienne ULg et al

Conference (2016, October 15)

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See detailIs there a place for BTR markers in renal osteodystrophy?
DELANAYE, Pierre ULg

Conference (2016, October 15)

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See detailMachine monstrueuse. Retour sur l'excès, l'exhibition et le gros plan
Jousten, Lison ULg

Conference (2016, October 14)

La communication propose de revenir sur certains aspects monstrueux du cinématographe. À la fois vectrice et créatrice d’un imaginaire intimement associé à la machine, il s’agit principalement d’envisager ... [more ▼]

La communication propose de revenir sur certains aspects monstrueux du cinématographe. À la fois vectrice et créatrice d’un imaginaire intimement associé à la machine, il s’agit principalement d’envisager comment cette « machine à voir » (Viva Paci, 2012) est aussi étroitement liée à la question de la monstruosité. [less ▲]

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See detailA full inference toolbox to measure multivariate relative dispersion
Aerts, Stéphanie ULg; Haesbroeck, Gentiane ULg

Conference (2016, October 14)

In the univariate context, coefficients of variation (CV) are widely used to compare the dispersion of a variable in several populations. When the comparison is based on p characteristics however, side-by ... [more ▼]

In the univariate context, coefficients of variation (CV) are widely used to compare the dispersion of a variable in several populations. When the comparison is based on p characteristics however, side-by-side comparison of marginal CV’s may lead to contradictions. In this talk, we present a multivariate coefficient of variation (MCV), defined as the inverse of the Mahalanobis distance between the mean and the origin, whose usefulness is demonstrated in some applications in finance and analytical chemistry. A full inference toolbox is provided for practitioners: several parametric and non-parametric bias-correction methods are suggested and compared, and some exact and approximate confidence intervals are built and analyzed in a simulation study. Finally, in order to meet the practical need to compare MCV’s in K populations, some asymptotic statistical testing procedures are derived, whose finite-sample performance is empirically assessed. Throughout the talk, the robustness of the techniques will be discussed. As a by-product, a test statistic allowing to reliably compare K univariate CV’s even in presence of outliers will be outlined. [less ▲]

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See detailTreg, Th17 and γδ T cells during normal and abortive pregnancy
Polese, Barbara ULg; Gridelet, Virginie ULg; Munaut, Carine ULg et al

Conference (2016, October 14)

Detailed reference viewed: 31 (5 ULg)
See detailSeasonal changes and steroid control of perineuronal nets in the song control system
Cornez, Gilles ULg; Shevchouk, Olesya ULg; Madison, Farrah et al

Conference (2016, October 14)

Perineuronal nets (PNNs) are aggregations of extracellular matrix components surrounding the soma of some neurons, mainly GABAergic interneurons expressing the calcium binding protein parvalbumin (PV ... [more ▼]

Perineuronal nets (PNNs) are aggregations of extracellular matrix components surrounding the soma of some neurons, mainly GABAergic interneurons expressing the calcium binding protein parvalbumin (PV+). In mammals, the development of PNNs limits synaptogenesis around PV+ neurons and PNNs have been validated as a marker characterizing the end of critical periods for some types of learning. In oscines, song learning is limited to critical periods either during ontogeny in close-ended learners such as zebra finches or during specific phases of the annual cycle in open-ended learners such as canaries or starlings. In zebra finches, PNN expression increases when the song crystalizes and this increase is markedly inhibited if juveniles are deprived from a tutor, which is known to delay the closure of the critical period for song learning. Nothing is known however about a possible role of PNNs in adult seasonal plasticity of open-ended learners. We compared PNNs expression and their colocalization with PV+ neurons in photosensitive, photostimulated, and photorefractory starlings. Although this treatment affected as expected the testes volumes, testosterone concentrations and volumes of song control nuclei, it did not markedly change the expression of PNNs or PV+ neurons in song control or auditory nuclei. In a second experiment, brains of female canaries implanted with testosterone for 1, 2, 9, or 21 days displayed an increase of the total numbers of PV+ neurons and PNNs in HVC, the total number of PNNs in nucleus robustusarcopallialis (RA), the density of PNNs in Area X and the %PV+ neurons surrounded by PNNs in RA and Area X. Interestingly the density of PNNs in song control nuclei progressively decreases from zebra finches to canaries to starlings in parallel with the increased song plasticity in these species supporting the notion that PNNs may limit brain and thus song plasticity in a species-typical manner. [less ▲]

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See detailCase report autour de cristalluries médicamenteuses atypiques
Castiglione, Vincent ULg; GADISSEUR, Romy ULg

Conference (2016, October 14)

We report here the cases of uncommon-shaped crystals in patient's urine. The first one is a 73years-old man with massive crystalluria observed in his microscopic urinalysis on Sedimax° (Menarini ... [more ▼]

We report here the cases of uncommon-shaped crystals in patient's urine. The first one is a 73years-old man with massive crystalluria observed in his microscopic urinalysis on Sedimax° (Menarini). Observed crystals had various shape (needle, stick, Feather...). The patient was hospitalized because of lactic acidosis due to suicide attempt by medication overdose. The following medication had been taken: prazepam, acetaminophen, tramadol and Triumeq°, a new anti-retroviral association of dolutegravir, abacavir and lamivudine. Infrared analysis of dryed urine didn"t allow to identify any common stone component, nor any medication. We further discuss about the possible implication of dolutegravir in crystalluria in this patient. Secondly, we show several N-acetylsulfamethoxazol (sulfamethoxazol metabolite) urine crystals detected in microscopic urinalysis of various patients. All had uncommon shape and were sometimes associated to acute kidney injury [less ▲]

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See detailExploring Metacognition as Support for Learning Transfer
Devlin, Marie; Draeger, John; Dvorakova, Lucie Sam et al

Conference (2016, October 14)

This presentation will share our efforts to investigate how metacognition might enhance the transfer of learning from one context to another. This topic is of relevance because the ability to transfer ... [more ▼]

This presentation will share our efforts to investigate how metacognition might enhance the transfer of learning from one context to another. This topic is of relevance because the ability to transfer one’s learning to new situations lies at the heart of lifelong learning and the employability of university graduates. [less ▲]

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See detailAzacytidine prevents experimental xenogeneic graft-versus-host disease without abrogating graft-versus-leukemia effects
Ehx, Grégory ULg; Fransolet, Gilles ULg; de Leval, Laurence ULg et al

Poster (2016, October 14)

The demethylating agent 5-azacytidine (AZA) has proven its efficacy as treatment for myelodysplastic syndrome and acute myeloid leukemia. In addition, AZA can demethylate FOXP3 intron 1 (FOXP3i1) leading ... [more ▼]

The demethylating agent 5-azacytidine (AZA) has proven its efficacy as treatment for myelodysplastic syndrome and acute myeloid leukemia. In addition, AZA can demethylate FOXP3 intron 1 (FOXP3i1) leading to the generation of regulatory T cells (Treg). Here, we investigated the impact of AZA on xenogeneic graft-versus-host disease (xGVHD) and graft-versus-leukemia effects in a humanized murine model of transplantation (human PBMCs-infused NSG mice), and described the impact of the drug on human T cells in vivo. We observed that AZA improved both survival and xGVHD scores. Further, AZA significantly decreased human T-cell proliferation as well as IFN-γ and TNF-α serum levels, and reduced the expression of GRANZYME B and PERFORIN 1 by cytotoxic T cells. In addition, AZA significantly increased Treg frequency through hypomethylation of FOXP3i1 as well as increased Treg proliferation. The later was subsequent to higher STAT5 signaling in Treg from AZA-treated mice, which resulted from higher IL-2 secretion by conventional T cells from AZA-treated mice itself secondary to demethylation of the IL-2 gene promoter by AZA. Importantly, Tregs harvested from AZA-treated mice were suppressive and stable over time since they persisted at high frequency in secondary transplant experiments. Finally, graft-versus-leukemia effects (assessed by growth inhibition of THP-1 cells, transfected to express the luciferase gene) were not abrogated by AZA. In summary, our data demonstrate that AZA prevents xGVHD without abrogating graft-versus-leukemia effects. These findings could serve of basis for further studies of GVHD prevention by AZA in acute myeloid leukemia patients offered an allogeneic transplantation. [less ▲]

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See detailDifferent and synergistic effect of 5-Azacytidine and Rapamycin on ex vivo expansion of natural human T Regulatory cells
Conteduca, Giuseppina ULg

Poster (2016, October 14)

Natural T regulatory cells (Treg) are challenging to expand ex vivo, and this has severely hindered in vivo evaluation of their therapeutic potential. 5-Azacytidine (5-azaC) and Rapamycin (RAPA) are ... [more ▼]

Natural T regulatory cells (Treg) are challenging to expand ex vivo, and this has severely hindered in vivo evaluation of their therapeutic potential. 5-Azacytidine (5-azaC) and Rapamycin (RAPA) are immunosuppressive drugs that promote selectively the expansion of CD4+CD25highFoxp3+ regulatory T cells.: We investigated whether 5-azaC and RAPA could be used together to promote the ex vivo expansion of Tregs purified from adult human peripheral blood.We found that 5-azaC helped maintain FOXP3 expression during the expansion process probably by promoting the conversion of T conventional (Tconv) in Treg, instead Rapa induces selectively apoptosis in Tconv cells and expansion in Treg. Addition of 5-azaC to RAPA treated cultures improved gene expression of FOXP3, CD25, STAT5 and TGF-B resulted in enhanced Treg expansion and suppressive activity. Also Rapa and 5-AzaC combination sustain Bcl-2 protein expression in Treg conferring resistance to apoptosis process. 5-azaC may have utility in ex vivo expansion of human Tregs, not as a single agent, but in combination with RAPA. These data may considerably accelerate the development of immunotherapeutic approaches for the treatment of autoimmune disease or posttransplant alloreactions by the adoptive transfer of nTreg cells [less ▲]

Detailed reference viewed: 15 (3 ULg)