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See detailAnalyse qualitative et quantitative des populations de norovirus murins générées lors d’infections in vitro synchrones et asynchrones avec des souches homologues : détection de phénomènes de dominance, d’interférence due aux particules non-infectieuses et d’exclusion à la surinfection
Di Felice, Elisabetta; Ludwig, Louisa ULg; Toffoli, Barbara et al

Poster (2016, March 24)

RÉSUMÉ Buts du travail La recombinaison est un des mécanismes moteurs de l’évolution génétique des norovirus. Malgré une détection fréquente de séquences recombinantes à partir d’échantillons de terrain ... [more ▼]

RÉSUMÉ Buts du travail La recombinaison est un des mécanismes moteurs de l’évolution génétique des norovirus. Malgré une détection fréquente de séquences recombinantes à partir d’échantillons de terrain, la reproduction du phénomène de recombinaison en conditions de laboratoire semble difficile. Utilisant le modèle du norovirus murin, cette étude a pour objectif d’évaluer de manière qualitative et quantitative les populations virales, y compris potentiellement recombinantes, générées lors de variations des conditions de temps et de multiplicité d’infection dans des expériences de coinfections ou de surinfections in vitro. Méthodes Des cellules RAW264.7 ont été inoculées par deux souches homologues de norovirus murins (infection primaire : Wu20 ; surinfection : CW1) en utilisant des multiplicités d’infection (MOI : Wu20 = 1; CW1= 0.1, 1 ou 10) et des temps d’inoculation (surinfection après un délai allant de 0 minutes à 24 heures) variables. Les surnageants ont été prélevés 24h post-surinfection et une quantification moléculaire discriminante sur la région 5’ du génome a été réalisée. Des cellules ont été ré-inoculées par ces surnageants et 36 isolats ont été amplifiés. Ces isolats ont été caractérisés moléculairement comme de type CW1, Wu20 ou recombinant par une méthode discriminante sur leurs extrémités génomiques 3’ et 5’. Les recombinants potentiels ont été séquencés sur la région génomique classiquement impliquée dans la recombinaison (chevauchement ORF 1/2). Résultats et discussion L’analyse des ratios des isolats a montré une tendance à une dominance potentielle de Wu20 sur CW1 pour les conditions de MOI relatives 0.1/1 et 1/1 avec un phénomène d’exclusion à la surinfection entre les temps t4 (4h post-infection primaire) et t8. Cependant, cette tendance n’a pas été détectée dans la condition de MOI relative 10/1. Ceci suggère une hypothèse de présence de particules défectives interférentes (PDI) dans la population de Wu20 qui pourrait interférer avec les étapes précoces de l’attachement et de l’entrée et donc modifier les ratios attendus 24h post-infection. La comparaison des ratios de copies génomiques a soutenu l’hypothèse de présence de PDI dans la population de Wu20 avec des ratios différents de ceux logiquement escomptés aux MOI relatives 0.1/1 et 1/1, et qui se sont vérifiés cette fois en condition 10/1 (condition dans laquelle CW1 peut retrouver une chance réelle dans la compétition à l’attachement et à la pénétration). Cependant le temps t1 de cette condition a dévié clairement de la tendance générale et pourrait constituer une population virale de choix pour la présence de recombinants ou suggérer un autre mécanisme par lequel CW1 pourrait momentanément être dominant par rapport à Wu20. L’exclusion à la surinfection a également pu être corroborée par l’analyse moléculaire quantitative. Trois isolats ont été détectés comme des recombinants potentiels mais les séquençages n’ont pu les confirmer. Les évènements de recombinaison pourraient avoir eu lieu sur une autre région que celle classiquement décrite. Cette étude permet de montrer que la composition de la population virale peut avoir un effet majeur sur la compétition entre deux norovirus. Elle suggère également l’existence d’un mécanisme d’exclusion à la surinfection. Elle confirme enfin que malgré les fréquentes détections de souches recombinantes in silico, le phénomène de recombinaison est difficile à reproduire in vitro chez les norovirus. [less ▲]

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See detailWavelet-based Methods to Study the Regularity of a Signal: from Theory to Practice
Kleyntssens, Thomas ULg; Nicolay, Samuel ULg

Conference (2016, March 23)

In this talk, I use the notion of wavelet to design multifractal formalisms. I present the theoritical results obtained on the generalized Snu spaces and I show the utility of these generalization ... [more ▼]

In this talk, I use the notion of wavelet to design multifractal formalisms. I present the theoritical results obtained on the generalized Snu spaces and I show the utility of these generalization. Besides, I also apply these formalisms on a practical example: the Mars topography. [less ▲]

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See detailRefractory ceramic molds fabrication by additive methods for low and high melting point metal alloys casting
Bister, Geoffroy; Deschuyteneer, Dorian; Hautcoeur, Dominique et al

Conference (2016, March 23)

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See detailEtude de dermatophytes isolés dans les services de revalidation et physiothérapie d’une structure hospitalière en région Liégeoise (Belgique)
SACHELI, Rosalie ULg; Utri, Tania ULg; Abdel-Sadick, Hidjab Abdoulaye ULg et al

Poster (2016, March 23)

Objectifs : Les dermatophytes sont responsables d’infections de la peau, des ongles et du cuir chevelu. Les espèces anthropophiles peuvent se transmettre d’une personne à une autre par un simple contact ... [more ▼]

Objectifs : Les dermatophytes sont responsables d’infections de la peau, des ongles et du cuir chevelu. Les espèces anthropophiles peuvent se transmettre d’une personne à une autre par un simple contact. Leur présence en milieu sportif (salles de sport, piscine, tatamis), douches collectives, vestiaires des écoles, a été largement décrite. Par contre il existe peu de littérature concernant les établissements de soins. C’est pourquoi, nous nous sommes intéressés au risque potentiel d’infection par des dermatophytes en milieu hospitalier et particulièrement dans les salles de kinésithérapie et de revalidation ainsi que dans une piscine du CHU de Liège. Matériel et méthodes : Trois sites du CHU de Liège ont été investigués: le site du Sart Tilman (ST), le site Ourthe Amblève (OA) et le site Notre-Dame des Bruyères (NDB). Les prélèvements ont été effectués en salle de revalidation et kinésithérapie ainsi qu’à la piscine de revalidation. Ces prélèvements ont été réalisés sur les surfaces à l’aide de géloses de contact (milieu de Sabouraud/chloramphénicol/actidione/gentamicine, Tritium Microbiologie, Pays-bas). L’identification des espèces fongiques a été réalisée par observation macro-microscopique des cultures, spectrométrie de masse (Maldi-Tof) et séquençage moléculaire. Résultats : Au total, 552 prélèvements ont été réalisés parmi lesquels 15 dermatophytes ont été recensés (2,72%). On retrouve: 7 T. rubrum, 7 T. interdigitale, 1 T. mentagrophytes var. mentagrophytes. Sur le site ST, 207 prélèvements ont été effectués parmi lesquels 4 T. rubrum, 1 T. interdigitale et 1 T. mentagrophytes var. mentagrophytes (zoophile). Sur le site OA, parmi les 226 prélèvements effectués, 4 Trichophyton interdigitale et 3 Trichophyton rubrum ont été retrouvés. Aucun dermatophyte n’a été isolé de l’eau de piscine ou pédiluve. Sur le site de NDB, sur 119 prélèvements, seuls 2 isolats de Trichophyton interdigitale ont été identifiés. Les prélèvements positifs pour les dermatophytes concernent des tapis de gymnastique, vélos, rameurs, balances, trampolines, demi-sphères d’équilibre, table de kinésithérapie, sols de douches et vestiaires de la piscine. Conclusion Grâce à ces investigations, nous avons pu mettre en évidence sur le matériel de revalidation et les sols des vestiaires, la présence de deux espèces anthropophiles, T. rubrum et T. interdigitale fréquemment impliquées dans les cas d’onychomycoses et atteintes cutanées. Une souche zoophile de T. mentagrophytes a également été mise en évidence. Cette étude démontre qu’un renforcement de la fréquence de nettoyage des sols et des instruments utilisés dans les salles de sport du CHU de Liège est nécessaire de façon à minimaliser les risques de contamination de patients et du personnel médical. [less ▲]

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See detailCalendars and rituals at Mari during the šakkanakkū period (end of the 3rd millennium B.C. – beginning of the 2nd)
Colonna d'Istria, Laurent ULg

Conference (2016, March 23)

The order of the months in the calendar at the end of the šakkanakkū period (19th century B.C.) is now well established. This calendar is largely similar to the one in use during the amorite period. This ... [more ▼]

The order of the months in the calendar at the end of the šakkanakkū period (19th century B.C.) is now well established. This calendar is largely similar to the one in use during the amorite period. This paper will focus on the rituals and festivals at Mari during the end of the šakkanakkū period: expenditures for temples, deities and rituals are mentioned in many administrative texts dated to the mid-19th century. Nevertheless, these texts are very patchy and the festivals are not clearly named. The latest excavation archaeological excavations at the site of Tell Hariri-Mari provided us with eleven administrative texts dated to the middle of the šakkanakkū period (i.e. UrIII period or slightly earlier). These texts reveal a calendar which is partly similar to the late šakkanakkū one. [less ▲]

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See detailGeophysical Investigation of the Pb-Zn deposit of Lontzen, Belgium
Evrard, Maxime ULg

Conference (2016, March 22)

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See detailThe use of protein-polysaccharide complexes to enhance protein delivery in CaCO3 microparticles
Ramalapa, Bathabile ULg; Crasson, Oscar ULg; Vandevenne, Marylène ULg et al

Conference (2016, March 22)

The role of protein therapeutics in modern medicine has increased considerably due to their potential to perform complex functions in the body that cannot be mimicked by simple chemical compounds. To ... [more ▼]

The role of protein therapeutics in modern medicine has increased considerably due to their potential to perform complex functions in the body that cannot be mimicked by simple chemical compounds. To increase the safety, stability and efficacy of protein therapeutics; there exists a need for delivery systems that are biocompatible, prevent premature degradation of bioactives and allow targeted delivery and controlled release. Calcium carbonate (CaCO3) has gained great favour for employment in protein delivery due to possibilities of controlling size, morphology and crystalline forms of particles by tuning the synthesis conditions. The aim of the present work was to assess the significance of polysaccharide-protein complexes in enhancing the encapsulation of proteins in CaCO3 microspheres. A Chitin Binding Domain (ChBD), reported to have affinity for hyaluronic acid, was inserted on β-lactamase enzyme to develop a chimeric protein. The chimeric protein retained the activity of the enzyme and the binding properties and was encapsulated in CaCO3 microspheres by a super critical CO2 (ScCO2) process using hyaluronic acid as a templating agent. The particles were characterised in terms of size, zeta potential, morphology and protein loading. The results obtained confirmed the affinity of the ChBD to hyaluronic acid towards the production of stable, vaterite microparticles. Protein assays demonstrated that the ChBD enhanced the encapsulation of protein by up to 10 fold. Confocal images also suggested high encapsulation of the chimeric protein compared to native protein. Thus the production of polysaccharide-protein complexes seems effective in enhancing the encapsulation of proteins in CaCO3 microparticles using the ScCO2 process. [less ▲]

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See detailUne généralisation du triangle de Pascal
Stipulanti, Manon ULg

Conference (2016, March 22)

We introduce a generalization of Pascal triangle based on binomial coefficients of finite words. These coefficients count the number of times a word appears as a subsequence of another finite word ... [more ▼]

We introduce a generalization of Pascal triangle based on binomial coefficients of finite words. These coefficients count the number of times a word appears as a subsequence of another finite word. Similarly to the Sierpinski gasket that can be built as the limit set, for the Hausdorff distance, of a convergent sequence of normalized compact blocks extracted from Pascal triangle modulo 2, we describe and study the first properties of the subset of [0, 1]×[0, 1] associated with this extended Pascal triangle modulo a prime p. [less ▲]

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See detailFeasibility study of repetitive diffusion MRI after Neoadjuvant radiotherapy for following tumor microenvironment.
LALLEMAND, François ULg; Leroi, Natacha ULg; Bahri, Mohamed Ali ULg et al

Conference (2016, March 22)

Purpose/Objective. Neoadjuvant radiotherapy (NeoRT) improves tumor local control and tumor resection in many cancers. The timing between the end of the NeoRT and surgery is mostly driven by the occurrence ... [more ▼]

Purpose/Objective. Neoadjuvant radiotherapy (NeoRT) improves tumor local control and tumor resection in many cancers. The timing between the end of the NeoRT and surgery is mostly driven by the occurrence of side effects or the tumor downsizing. We previously demonstrated in an in vivo model that the timing of surgery and the schedule of NeoRT influenced the tumor dissemination. Here, our aim is to evaluate with functional MRI (fMRI) the impact of the radiation treatment on the tumor microenvironment and subsequently to identify non-invasive markers helping to determine the best timing to perform surgery for avoiding tumor spreading. First, we needed to demonstrate the feasibility of repetitive MRI imaging after NeoRT in mice. Material/methods. We used two models of NeoRT we previously developed in mice: MDA-MB 231 and 4T1 cells implanted in the flank of mice. When tumors reached the planned volume, they are irradiated with 2x5 Gy and then surgically removed at different time points after RT. In the mean time between the end of RT and the surgical procedure, mice were imaged in a 9,4T Agilent® MRI. Diffusion Weighted (DW) -MRI was performed every 2 days between RT and surgery. For each tumors we acquired 8 slices of 1 mm thickness and 0.5 mm gap with an “in plane voxel resolution” of 0.5 mm. For DW-MRI, we performed FSEMS (Fast Spin Echo MultiSlice) sequences, with 9 different B-values (from 40 to 1000) and B0, in the 3 main directions. We also performed IVIM (IntraVoxel Incoherent Motion) analysis, in the aim to obtain information on intravascular diffusion, related to perfusion (F: perfusion factor) and subsequently tumor vessels perfusion. Results. As preliminary results, with the MBA-MB 231 we observed a significant increase of F at day 6 after irradiation than a decrease and stabilization until surgery. No other modifications of the MRI signal, ADC, D or D* were observed. We observed similar results with 4T1 cells, F increased at day 3 than returned to initial signal. The difference in the timing of the peak of F can be related to the difference in tumor growth between MBA-MB 231 and 4T1 (four weeks vs one week). Conclusion. For the first time, we demonstrate the feasibility of repetitive fMRI imaging in mice models after NeoRT. With these models, we show a significant peak of the perfusion factor (F) at day 6 or day 3. This change occurs between the two previous time points of surgery demonstrating a difference in the metastatic spreading. Indeed, after a NeoRT of 2X5Gy we observed more metastases in the lung when MDA-MB 231 tumor bearing mice are operated 4 days after RT compared to 11 days. These preliminary results are very promising for identifying noninvasive markers for determining the best timing for surgery. [less ▲]

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See detailOsteopontin predicts radiotherapy response of glioblastoma patients : new role in DNA damage repair
Henry, Aurélie ULg; Nokin, Marie-Julie; Leroi, Natacha ULg et al

Conference (2016, March 22)

- Introduction: Glioblastoma (GBM) is the most aggressive and common solid human brain tumor. Because of GBM heterogeneity, location and aggressiveness, none of the available treatment is curative. These ... [more ▼]

- Introduction: Glioblastoma (GBM) is the most aggressive and common solid human brain tumor. Because of GBM heterogeneity, location and aggressiveness, none of the available treatment is curative. These treatments include maximal surgical resection, radiotherapy and concomitant or adjuvant chemotherapy with Temozolomide. However, the prognosis of adult patients with GBM remains poor and the survival outcome after treatment does not exceed 15 months. GBM-composing cells have developed many strategies to counteract these current therapies. Among the wide hallmarks acquired to survive, high osteopontin (OPN) expression correlates with lower overall and disease-free/relapse-free survival in all tumors combined, as well in brain cancer. Our recent study (Lamour V and Henry A, IJC 2015) has demonstrated the role of OPN in the tumorigenicity of glioblastoma cells and its importance in the maintenance of the stem characters. In the continuation of this work, our recent studies focused on the potential role of OPN in the resistance of GBM cells to radiotherapy and its potential implication in the initiation of Double Strand Breaks (DSBs) repair mechanisms. - Aims: In the context of this study, different GBM cell lines (U251-MG, U87-MG and U87 Viii) were used to assess the role of OPN in the initiation of the DSBs repair mechanism after an exposure to gamma-irradiation. - Methods and results: We performed the transient transfection of different GBM cell lines (U251-MG, U87-MG and U87-MG overexpressing EGFR VIII) with siRNAs specifically directed against OPN. After irradiation, all these OPN-depleted cells consistently showed a lower induction of γ–H2AX compared to control (irrelevant siRNA) as evidenced by western blot and immunofluorescence techniques. Thereafter, clonogenic assays allowed to prove that the survival of OPN-depleted cells was affected after an exposure to irradiation. To assess the importance of OPN expression in the response to radiotherapy, an heterotopic xenograft model was used. In brief, IPTG-inducible U87 shOPN clones were injected subcutaneously in NOD-SCID mice and were allowed to form a tumor. When average tumor volume reached a predetermined size range, mice were treated (or not) with IPTG by intraperitoneal injection during five days. At the end of the treatment, tumors were selectively exposed to gamma-irradiation by using a small animal irradiator X-RAD 225Cx (Precision X-Ray Inc., North Branford, CT). One week later, mice were sacrificed and tumors were measured. In this pilot study, we observed that mice in which the tumor was depleted in OPN displayed a slight regression in the tumor growth compared to mice that received radiotherapy alone (no IPTG), where the tumor volume remained constant. - Conclusions: Taken together, these preliminary data meet the fact that OPN is important in the response of GBM to radiotherapy. The in vitro results converge to the fact that OPN might be implicated in the initiation of the DSBs repair following irradiation. Currently, we would like to investigate this hypothesis in vivo but also to check the effect of OPN depletion combined to radiotherapy on the survival of mice in an orthotopic xenograft model. [less ▲]

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See detailEnhanced biomass production of a novel Acetobacter strain isolated from Moroccan biotopes using response surface methodology approach
Mounir, Majid ULg; Hamas, Khadija; Tamraoui, Khadija et al

Conference (2016, March 21)

The objective of this work was first the isolation of novel acetic acid bacteria strains from natural Moroccan habitats, and then, the evaluation of their ability to produce microbial starters for vinegar ... [more ▼]

The objective of this work was first the isolation of novel acetic acid bacteria strains from natural Moroccan habitats, and then, the evaluation of their ability to produce microbial starters for vinegar production in large-scale. The isolation was made from figs, dates, cactus, and traditional fruit vinegars. Four strains, selected from a total of 63 isolates were confirmed to be belonged to Acetobacter species according to biochemical tests and molecular study based on 16s rDNA sequence analysis. Acetic acid fermentation tests, performed on date and apple fermented juices by the selected Acetobacter strains, showed high capacity of acidification. The most efficient strain, isolated from cactus vinegar, yielded an acidity of about 42.5 g/L on apple juice. A cell growth optimization was carried out on the most efficient strain using the response surface methodology (RSM). The linear, quadratic and interaction effects of four factors; ethanol, acetic acid, glucose and pH were studied by the application of a central composite design. 30 experiments were designed to predict the maximum concentration of cell biomass. The optimal calculated values of ethanol, acetic acid, glucose and pH allowing the prediction of the maximum biomass production (2.2 g/L) were 28.18 g/L, 10.12 g/L, 15.15 g/L and 5.33, respectively. Subsequently, further batch fermentations were carried out in a 6 L lab-bioreactor using the optimased culture medium. The results were in line with the predict values. It was concluded that the studied strain is well suited to be used as parental strain to prepare a starter for vinegar fruit production. [less ▲]

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See detail“Rhythm and Repetition in Caryl Phillips’s Dancing in the Dark”
Mascoli, Giulia ULg

Conference (2016, March 20)

My proposal is to deal with Dancing in the Dark (London: Vintage, 2005), a novel by Caryl Phillips, a contemporary British author of Caribbean descent. This narrative is devoted to the Caribbean American ... [more ▼]

My proposal is to deal with Dancing in the Dark (London: Vintage, 2005), a novel by Caryl Phillips, a contemporary British author of Caribbean descent. This narrative is devoted to the Caribbean American entertainer Bert Williams (1874–1922) who was the first black performer in the Ziegfield Follies and it traces his frustrating life as a black performer who had to blackface. Like most of Phillips’s literary production, Dancing in the Dark is shaped by music, both thematically –there are scenes involving musical performances, lyrics interspersed throughout the novel– and formally through the recurrent and creative use of repetitions and meaningful variations in rhythm, and sonic effects. Indeed, various elements of sound are present through poetic language and forms to emphasize elements of rhythm: repetitive devices such as rhymes, meters and alliterations. My contention is that these rhythmic devices partake in the emotional impact of Phillips’s writing; sonic elements emphasize the musical properties of language, strike the reader and prevent them from forgetting the traumatic experience of Bert. Through repetition, they transfer the character’s traumatic experience into the writing and create a sense of sympathy with the reader which privileges immediate empathy. If Bert Williams has been largely forgotten until recently, I believe that Phillips’s rhythmic prose will enable Bert’s story to resonate in the reader’s mind long after closing the book. [less ▲]

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See detailLes PCSK9 : la mort des statines ?
RADERMECKER, Régis ULg

Conference (2016, March 19)

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See detailLes pays émergents : vecteur de sécurité alimentaire en Afrique ? le cas du Brésil au Mozambique
WCusson, Gabrielle ULg

Conference (2016, March 19)

Cette communication a pour objectif d’analyser le rôle des pays émergents dans la coopération agricole en Afrique pour assurer la sécurité alimentaire et énergétique du continent, et plus particulièrement ... [more ▼]

Cette communication a pour objectif d’analyser le rôle des pays émergents dans la coopération agricole en Afrique pour assurer la sécurité alimentaire et énergétique du continent, et plus particulièrement celui du Brésil au Mozambique. Parmi les pays émergents, la Chine, l’Inde et le Brésil s’affichent dorénavant comme des puissances agricoles à l’échelle internationale et détiennent une expertise particulière qu’ils souhaitent partager avec l’Afrique afin de soutenir sa révolution agraire et son insertion au marché mondial. Cependant, cette coopération Sud-Sud (CSS) ne semble pas exempte de bénéfices politiques et commerciaux à l’égard des pays donateurs. Ainsi, les pays émergents proposent-ils un modèle de coopération et de développement différent et solidaire ou reproduisent-ils la structure d’aide traditionnelle Nord-Sud soutenue par les institutions financières internationales? Quels sont les intérêts des puissances émergentes à participer à la nouvelle révolution verte en Afrique ? Plus précisément, cette analyse portera sur la stratégie de CSS du Brésil au Mozambique via le projet ProSAVANA, un projet de coopération triangulaire développé avec le Japon qui vise le transfert du savoir-faire technique et technologique agraire du Brésil dans les savanes africaines à des fins de production de biocarburants; un enjeu clé pour le Brésil. Pour répondre à la question de recherche, nous confronterons le discours officiel du Brésil en terme de CSS avec la réalité qui se dessine au Mozambique. Pour ce faire, nous nous appuierons sur les théories critiques de la nouvelle économie politique. [less ▲]

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See detailClinical and molecular classification of glioblastoma patients
Lambert, Jérémy ULg; Kaoma, Tony; Van Dyck, Eric et al

Poster (2016, March 19)

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See detailThe Islamic coinage of Barqa from the conquest up to the advent of the Fatimids
Bauden, Frédéric ULg

Conference (2016, March 19)

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See detailThérapeutiques conservatrices des tendinopathies : quoi de neuf ?
Kaux, Jean-François ULg

in 11ème Congrès d'actualités diagnostiques, éthiques et thérapeutiques de l'arrondissement de Dinant (2016, March 19)

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See detailGoro Gheri as the "perfect secretary"?
Miesse, Hélène ULg

Conference (2016, March 19)

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See detailÉcrire (malgré) l'espace aéré. Yves Berger et Edward Abbey au seuil du parc national américain
Di Gregorio, Luca ULg

Conference (2016, March 18)

Edward Abbey et Yves Berger ont nourri l’essentiel de leurs œuvres de leur fascination commune pour l’Ouest américain : plus spécifiquement pour la région du Grand Bassin et le pays des canyons – pays de ... [more ▼]

Edward Abbey et Yves Berger ont nourri l’essentiel de leurs œuvres de leur fascination commune pour l’Ouest américain : plus spécifiquement pour la région du Grand Bassin et le pays des canyons – pays de sable et de grès, pays minéral, sidéral, qui concentre plusieurs des plus fameux parcs naturels des États-Unis. Mais si leur passion s’attache au même objet d’élection – les paysages sublimes du Sud-Ouest –, l’un et l’autre divergent par les voies qu’ils empruntent et les points de vue d’où ils se postent pour le goûter, et surtout pour en rendre compte par l’écriture. En effet, un Océan entier sépare leurs positions vis-à-vis de la nature américaine – mais pas uniquement : chacun représente aussi, pour son pays respectif, une bonne part de l’ethos et de l’habitus qui y valorise d’ordinaire l’écrivain. Ancien ranger saisonnier, Abbey est un écrivain activiste et baroudeur, s’affichant en prise directe avec le terrain, tandis que Berger, protagoniste influent du milieu littéraro-éditorial parisien, rêve d’Amérique en même temps qu’il siège parmi les jurés du Goncourt. En première analyse donc, rien, hormis une vague parenté de génération et un goût du Nouveau Monde, ne justifierait l’association de deux écrivains aussi éloignés l’un de l’autre. Mais nonobstant ce gouffre sociogéographique, ce qui, en dernière analyse, rapproche nos deux auteurs, réside dans l’obstacle commun qui perturbe leur abord de l’Amérique sauvage: le National Park Service et son immense réseau d’espaces aérés naturels, quadrillant, pour les protéger (et les promouvoir), les plus fameux paysages de l’Ouest. Là où Abbey rejoint Berger, et réciproquement, c’est dans cette façon de mal assumer l’importun isolant phénoménologique qu’est le parc, d’éprouver une nette complication à écrire et ressentir la Nature au travers de son interférence. Phénomène non-naturel par excellence, ce seuil que pose le parcage leur pose, à eux, un lourd problème, puisqu’il leur renvoie la part d’impossible du rapport qu’ils désirent cultiver avec le Grand Ouest. Là encore cependant, même cet « impossible » se manifeste différemment à chacun. Comment, pour le ranger Abbey, évoquer une intimité native avec le cosmos en dépit du cadenassage institutionnel dont il est partie prenante? Comment, pour le Français Berger, passer dignement en Amérique à la façon d’un vrai voyageur, en évitant de rendre l’effet d’un touriste anonyme, téléguidé par le balisage et la signalétique du parc naturel ? Heurtant le désir d’immanence à la wilderness de l’un, le parc compromet aussi l’aspiration au voyage authentique de l’autre : tel est le « problème » du parc, dont on analysera ici quelques symptômes et solutions poétiques au sein de deux œuvres ayant pour cadre la région des Four Corners1 : l’incontournable Desert Solitaire (1968) d’Abbey, véritable bible du Nature Writing en Amérique, dialoguera ainsi avec La Pierre et le Saguaro (Prix de la langue française, 1990) d’Yves Berger. Mais préalablement, et alors que le National Park Service fête cette année son centenaire, il convient de faire un rapide point théorique et phénoménologique sur ce qu’implique et recouvre l’objet culturel « parc américain ». [less ▲]

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See detail“Everything was losing definition and outline”: Re-membering Trauma Fiction in Gail Jones’s Sorry
Belleflamme, Valérie-Anne ULg

Conference (2016, March 18)

In an article, Australian novelist and essayist Gail Jones confesses of her novel Sorry that it has “a political-allegorical aspect – as one would expect, claiming such a title” (2008, 79). Published in ... [more ▼]

In an article, Australian novelist and essayist Gail Jones confesses of her novel Sorry that it has “a political-allegorical aspect – as one would expect, claiming such a title” (2008, 79). Published in 2007, that is, one year prior to the formal apology delivered by the Australian government to the Aborigines and Torres Strait Islanders, Sorry engages in a reflection on the ethics of reconciliation. Written in response to Jones’s wish to acknowledge the debt to the Stolen Generations, the novel also offers new possibilities of ethical mourning, allowing the dead to return and the voiceless to speak. My paper will seek to explore the ways in which Jones draws on trauma fiction to bypass not only the unsayable dimension of Australia’s history and what she elsewhere criticises as the trauma model’s “transferential gesture of victim surrogacy” symptomatic of postcolonising settler cultures (2004, 162) but also the representational difficulties inherent in trauma. Moreover, it is by introducing into her novel the concept of traumatic time, “a time that is broken, and […] recursive” (qtd. in Block 2008) and which mirrors on the level of form and structure the effects that trauma exerts on its victims, that Jones she recreates a narrative model that echoes an Australian discourse pre-dating the Bringing Them Home report – that is tinged with amnesia, fragmented memories, and silence –, against which she will assert her own counter-discourse. Works Cited: - Block, Summer. 09 May 2008. “Interview: Gail Jones.” Interview. January Magazine. Web. 16 Jan. 2013. - Jones, Gail. 2004. “Sorry-in-the-Sky: Empathetic Unsettlement, Mourning, and the Stolen Generations.” In Imagining Australia: Literature and Culture in the New New World, edited by Judith Ryan and Chris Wallace-Crabbe, 159-171. Cambridge, MA: Harvard University Press. - Jones, Gail. 2007. Sorry. London: Harvill Secker. - Jones, Gail. 2008. “Speaking Shadows: Justice and the Poetic.” In Just Words?: Australian Authors Writing for Justice, edited by Bernadette Brennan, 76-86. St Lucia: University of Queensland Press. [less ▲]

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See detailMarker et mémoire
Pieron, Julien ULg

Conference (2016, March 18)

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See detailPrecision design of novel bio-based and ethylene-based copolymers: application to advanced nanocomposites
Scholten, Philip ULg; Detrembleur, Christophe ULg; Meier, Michaël et al

Conference (2016, March 18)

Polyolefins are an inexpensive class of compounds that can be used to prepare a plethora of different materials. Poly(ethylene) is the worldwide most produced polymer and is mostly synthesised by free ... [more ▼]

Polyolefins are an inexpensive class of compounds that can be used to prepare a plethora of different materials. Poly(ethylene) is the worldwide most produced polymer and is mostly synthesised by free radical polymerisation or catalytic coordination insertion using high temperature and pressure. The controlled radical polymerisation of ethylene is very difficult to achieve because of secondary reactions of this unconjugated monomer, e.g. chain transfer and termination reactions. Cobalt-mediated radical polymerisation (CMRP) represents a solution to control its polymerisation in mild conditions: in a reversible deactivation mechanism, a cobalt complex reversibly traps the active growing chains and converts them into dormant species, avoiding side reactions and allowing for a controlled polymerisation. Using CMRP, statistical copolymers of ethylene and vinyl acetate (VAc) have been synthesised, as well as block-like and block copolymers. Furthermore, functionalisation of the α- and ω-chain ends are now possible. Incorporating other monomers, e.g. vinyl esters or vinyl amides, into an ethylene copolymer by CMRP will lead to completely new and highly interesting materials which may act as compatibilisers for the dispersion of natural polymers, such as cellulose, into various polymer matrices. The goal of this work is to design novel well-defined functional polyethylenes that are expected to improve the dispersion of natural polymers into polyolefins. [less ▲]

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See detailRegain of fitness through in vitro replication for a recombinant murine norovirus
de Oliveira-Filho, Edmilson; Ludwig, Louisa ULg; Toffoli, Barbara et al

Poster (2016, March 18)

INTRODUCTION Molecular mechanisms driving norovirus evolution are the accumulation of point mutations and recombination. Recombination can create considerable changes in viruses, allowing for complete ... [more ▼]

INTRODUCTION Molecular mechanisms driving norovirus evolution are the accumulation of point mutations and recombination. Recombination can create considerable changes in viruses, allowing for complete antigenic shifts, host jumps and fitness and pathogenesis modifications. Mathijs et al. recently isolated a viable recombinant murine norovirus (RecMNV) in vitro after coinfection of two parental MNV strains (MNV1-CW1 and -WU20) in a mouse leukaemic monocyte-macrophage cell line (RAW 264.7). The ensuing RecMNV possessed reduced in vitro fitness compared to its parental strains but has also been shown to have retained in vivo infectivity (Mathijs et al, submitted). The aim of this study was to follow the replicative and genetic adaptations of RecMNV over serial in vitro passages in order to characterise its capability of replicative fitness adaptation. MATERIALS AND METHODS: RecMNV was serially replicated in vitro in monolayers of RAW 264.7 cells over ten passages. Following a first initial infection at an MOI of 0.05, cell layers were consecutively infected with 100 μl neat supernatant of the preceding passage. Two independent lysis plaque assays were performed in triplicate with RecMNV progenies resulting from the first (early) and tenth (late) passage (RecE and RecL). Viral plaque sizes of RecE and RecL were measured with image processing program Image J and statistical analyses of plaque size diameters were subsequently performed. To obtain the complete genome sequences of RecE and RecL, a sequencing strategy was developed in which the MNV genome was divided into seven regions and amplification was performed using overlapping primers. Nucleotide sequences of RecE and RecL were analysed via BioEdit Sequence Editor. Growth curves of RecE and RecL progenies were established for high (10) or low MOI (0.01). RESULTS After ten in vitro passages, viral lysis plaque size diameters had increased significantly. Molecular analysis of RecMNV and both parental strains showed nine nucleotide mutations in the RecMNV genome, comprising three non-silent mutations. In addition, a mutation at position 7245 (A187G) introduced a stop codon, resulting in a 20 AA shorter VP2 in RecMNV (for both RecE and RecL). A comparison of RecE and RecL revealed four non-silent mutations in the NS1-2 and NS7 region of ORF1, two of which were present in the latter region (G1384D and S1393N). DISCUSSION This is the first study in which the fitness of a recombinant NoV strain was evaluated in vitro. Our data provides evidence of viral adaptation to a new environment (here a cell culture system) after a recombination event. Evidence of gain-of-function of RecMNV was demonstrated by differences in growth curves and viral lysis plaque size. In addition, non-silent mutations associated to the gain-of-function/in vitro adaptation were detected. It is noteworthy, that the mutation causing a shorter VP2 in RecE and RecL did not compromise its ability to infect and replicate either in vitro or in vivo (Mathijs et al, submitted). As a perspective we should like to characterise the precise mutation(s) responsible for the fitness regain via infectious clone assay. [less ▲]

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See detailPancreatic Beta Cell Regeneration: Duct Cells Act as Progenitors in Adult Zebrafish
Bergemann, David ULg; Ghaye, Aurélie; Tarifeño, Estefania et al

Poster (2016, March 18)

Diabetes is characterized by the loss of insulin producing beta cells. Although different therapeutic strategies do exist, they lack precise and dynamic control of glycemia as carried out by endogenous ... [more ▼]

Diabetes is characterized by the loss of insulin producing beta cells. Although different therapeutic strategies do exist, they lack precise and dynamic control of glycemia as carried out by endogenous beta cells. One promising alternative is to replenish the pancreas with bona fide functional beta cells by triggering regeneration mechanisms. Previous studies have shown beta cell neogenesis but still remain controversial about their origin as they used different models. However, among the different hypotheses, it is tempting to assume that pancreatic ducts contain progenitor/precursor cells in adults. The latter is supported by the fact that the embryonic duct epithelium gives rise to the endocrine lineage, and that in healthy and diabetic human adults, insulin positive cells could be found next to or in pancreatic ducts. Despite these observations, mammals show very limited regenerative capabilities, making it difficult to investigate those mechanisms. In contrast, zebrafish are extensively used for regeneration studies. The ability of adult zebrafish to regenerate its beta cells and restore normoglycemia after massive beta cell ablation has already been shown. Our work focuses on the understanding of the underlying mechanisms leading to this retained potential. Here we show that adult pancreatic duct cells act as progenitors, giving rise to beta cells, in physiological and induced diabetic condition in vivo. To get insight into this process, we conducted RNA-seq experiments on zebrafish pancreatic duct cells. By this mean we could identify new ductal markers and noticed that adult duct cells also show strong expression of embryonic pancreatic progenitor markers. In our ongoing comparative analyses we are deciphering the key genes and pathways needed to set in motion the regenerative machinery. The differences between zebrafish and mammal duct cells that will thereby be underlined might then be transposed to mammalian model s to restore regenerative processes. [less ▲]

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See detailRecollection versus familiarity in normal aging and in mild cognitive impairment: Impact of test format
Gilsoul, Jessica ULg; Simon, Jessica ULg; SALMON, Eric ULg et al

Poster (2016, March 18)

Objectives. Memory retrieval typically involves a combination of recollection and familiarity. However, test format can promote one or the other process (Norman & O’Reilly, 2003). The aim of this study ... [more ▼]

Objectives. Memory retrieval typically involves a combination of recollection and familiarity. However, test format can promote one or the other process (Norman & O’Reilly, 2003). The aim of this study was to investigate the impact of test format on recollection and familiarity in normal aging and in mild cognitive impairment (MCI). Methods. Seventy young participants (18-30 years), 65 “younger-old” (55- 69 years), 53 “older-old” (70-85 years), and 13 MCIs (55-82 years) were enrolled. In the “forced-choice” task, they had to recognize which picture, among three, was presented during the encoding stage. In the “yes/no” task, they had to judge whether each item, successively presented, was previously seen or not. In each task, they had to give a “Remember/Know/Guess” judgment. Results. Group × Format repeated measures ANOVAs revealed that young people had better recognition performance (d’) than “younger-old”, which were better than “older-old” and MCIs. Moreover, young people used familiarity more accurately than both groups of old participants and MCIs, with MCIs being equivalent to “younger-old” and “older-old”. However, MCIs displayed a high rate of familiarity-based false alarms. The resort to recollection decreased with age and in MCIs. Finally, Group × Format interaction revealed that young people (but not the other groups) could use recollection more often in the “forcedchoice” task compared to the “yes/no” task. Conclusions. Recollection and familiarity decline progressively in healthy aging. In MCI, recollection is more affected than familiarity, but patients demonstrated a more liberal use of familiarity. Finally, test format did not influence strongly the results. [less ▲]

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See detailWill Big Data Deliver Its Promised Productivity Growth?
Artige, Lionel ULg

Conference (2016, March 18)

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See detailThe impact of cognitive reserve on recognition memory performance is dependent of the task format in healthy aging
Simon, Jessica ULg; Gilsoul, Jessica ULg; Bastin, Christine ULg

Poster (2016, March 17)

Objective: According to the cognitive reserve hypothesis (Stern, 2009), individuals who have developed a high level of reserve should resist better to the effects of aging than individuals with lower ... [more ▼]

Objective: According to the cognitive reserve hypothesis (Stern, 2009), individuals who have developed a high level of reserve should resist better to the effects of aging than individuals with lower cognitive reserve. In this study, we identified the factors of cognitive reserve that impact most memory performance in aging. Methods: 118 healthy older participants performed one yes/no recognition task and one 3-alternative forced-choice recognition task. For each recognized item, participants provided a Remember/Know/Guess judgment. Furthermore, participants completed a questionnaire assessing different aspects of cognitive reserve (level of education, occupation, physical, social, cultural and intellectual activities). We determined the moderators of cognitive reserve that explain a significant proportion of variance for each memory index through stepwise regression analyzes (p<0.05). Results: In the forced-choice test, the level of education explained positively the use of recollection and negatively the level of false alarms associated with familiarity. In the yes/no recognition task, the precision of recognition was explained positively by the physical activities. Recollection was positively explained by the physical activities and the level of education. Finally, the level of false alarms associated with familiarity was explained negatively by the level of education although the precision of the use of the familiarity is explained positively by physical activities. Conclusion: The more older adults were educated and/or were practicing physical activities, the better their recollection was. The impact of the moderators of the cognitive reserve is dependent on the format of the recognition task. [less ▲]

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See detail“From another angle”: the Australian Reconciliation in Gail Jones’s Sorry and Five Bells
Belleflamme, Valérie-Anne ULg

Conference (2016, March 17)

On 26 May 2000, an estimated 250,000 people – Australian novelist and essayist Gail Jones included – walked across the Sydney Harbour Bridge in support of the Australian Reconciliation process. More ... [more ▼]

On 26 May 2000, an estimated 250,000 people – Australian novelist and essayist Gail Jones included – walked across the Sydney Harbour Bridge in support of the Australian Reconciliation process. More importantly, eight years later, Jones claimed that “in writing [her novel Sorry] [she] rehearsed [her] own concern that the reconciliation process not be forgotten – since it has certainly faded from the political agenda since the bridge walk of 2000[” (2008: 84). This and her claim that “the heartwarming Sorry Books [...] ought seriously to be considered within the genre of the poetics of political dissent, and not as casual or sentimental acts of mere signature” (2008: 164) are indicative of Jones’s writing and of her wish to subvert the stereotypical and ambiguous discursive manifestations of the Australian Reconciliation. By the same token, her novels Sorry (2007) and Five Bells (2011) offer a complex picture of the ethics of reconciliation, namely one that includes “an admission of uncertainty, a calculation of difficulty, and an awareness that justice – and human relations – is rarely written in black and white” (Jones 2008: 86). My paper will thus seek to explore how Jones, by drawing on forms of narrative indirections in both, Sorry and Five Bells, distances herself from white Australian writers who deal with the Stolen Generations in a way that seems to appropriate Aboriginal and Torres Strait Islander peoples’ experiences. Sorry and Five Bells, then, offer an alternative to standard reconciliation practices, with a view to bridging the gap between white Australia’s history and the history of the Aborigines. References: - Jones, Gail. 2008a. Sorry. London: Vintage. - Jones, Gail. 2008b. Speaking shadows: Justice and the poetic. In Just Words?: Australian Authors Writing for Justice, Bernadette Brennan (ed.). St Lucia, Qld.: University of Queensland, 76-86. - Jones, Gail. 2012. Five Bells. London: Vintage. [less ▲]

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See detailLa Province au défi de la Sixième réforme de l'État
Grandjean, Geoffrey ULg

Conference (2016, March 17)

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See detail"Parcours fléchés. Seuils et traversées dans l'œuvre de Marc-Antoine Mathieu"
Belloi, Livio ULg

Conference (2016, March 17)

Cette communication se propose d'étudier "Sens" (2014), le dernier album du dessinateur français Marc-Antoine Mathieu. Plus spécifiquement, il s'agissait, conformément au thème directeur du Congrès de St ... [more ▼]

Cette communication se propose d'étudier "Sens" (2014), le dernier album du dessinateur français Marc-Antoine Mathieu. Plus spécifiquement, il s'agissait, conformément au thème directeur du Congrès de St. Louis, d'examiner l'œuvre de Mathieu sous l'angle de son dispositif péritextuel (première de couverture, prologue, couverture intérieure). [less ▲]

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See detailThe Bullshit Abstract: From Critique to Reflexive Practice
Van Oudheusden, Michiel ULg; Charlier, Nathan ULg; Claisse, Frédéric ULg

Conference (2016, March 17)

Academics use the abstract to summarize and communicate a research paper’s focus, methods, findings, and conclusions. However, not all abstracts are convincing. Many are bland, uninspired, or outright ... [more ▼]

Academics use the abstract to summarize and communicate a research paper’s focus, methods, findings, and conclusions. However, not all abstracts are convincing. Many are bland, uninspired, or outright stupid, as authors do not always know what they want to say or how to communicate complex research in the space of a few hundred words. They hence often convey the kind of “intelligent stupidity,” which Robert Musil (1937) said could hardly be “distinguished from talent, progress, hope or improvement.” By implication, abstracts are prone to contain and perpetuate “academic bullshit” (Frankfurt 2005), broadly understood as forms of academic expression that meet the stylistic academic standards but generate content that is deceptive, doubtful, or irrelevant. Taking this inherent disposition towards bullshit in the academic abstract as its entry point, this paper presents ten self-authored “bullshit abstracts,” which draw inspiration from various academic fields. Far from denouncing bullshit outright, it acknowledges the inevitable character of bullshit in academic writing (Eubanks and Schaeffer 2008). It urges academics to reflexively consider, and perform, their roles as researchers and writers in view of the challenges they face today, such as reputation management and the pressure in academia to publish or perish; and their complete lack of sensitivity to the odorous aspects of writing. [less ▲]

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See detailEnhancing the salience of perceptual fluency improves familiarity-based recognition memory in aging
Bastin, Christine ULg; Willems, Sylvie ULg

Poster (2016, March 17)

Objective. Normal aging is characterized by decreased recollection, but better preserved familiarity. Memory tasks that facilitate the use of familiarity should allow attenuating age-related differences ... [more ▼]

Objective. Normal aging is characterized by decreased recollection, but better preserved familiarity. Memory tasks that facilitate the use of familiarity should allow attenuating age-related differences in memory. The study tested two hypotheses: (1) can the reliance on familiarity during recognition memory be promoted by increasing the difference in perceptual processing fluency between old and new items; (2) can this manipulation reduce age-related difficulties in episodic memory? Methods. Twenty-four young and 24 older adults performed two verbal recognition memory tasks. In the No-Overlap task, target words and new words did not share any letter. Prior exposition to the target words thus induced increased processing fluency of the words and letters, so that fluency difference was a salient and reliable cue to discriminate between old and new words. In the Overlap task, target and new words had letters in common, so fluency cues were less useful. Recollection and familiarity was assessed with the Remember/Know/Guess paradigm. Results. There was an age effect on recollection but intact familiarity. Moreover, (1) memory performance was better in the No Overlap than the Overlap task, with a greater hit rate and a smaller false alarm rate associated with familiarity. (2) Age-related differences in recognition accuracy (hits – false alarms) were significantly attenuated in the No Overlap task compared to the Overlap task. Conclusion. These findings suggest that minimizing the perceptual similarity between targets and distractors, and thus increasing processing fluency differences, allowed to reduce the effect of age on recognition memory performance by facilitating the use of familiarity. [less ▲]

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See detailComment lire les textes informatifs au début du secondaire?
De Croix, Séverine ULg

Conference (2016, March 17)

Pourquoi et comment apprendre à lire les textes informatifs dans les différentes disciplines au début de l'enseignement secondaire ? Pour tenter de répondre à cette double question, l'auteure s'efforce ... [more ▼]

Pourquoi et comment apprendre à lire les textes informatifs dans les différentes disciplines au début de l'enseignement secondaire ? Pour tenter de répondre à cette double question, l'auteure s'efforce tout d'abord d'identifier les spécificités de ces textes et des modes de lecture qu'ils impliquent. Elle propose ensuite quelques repères, fondés sur différents travaux de recherche récents, quant aux pratiques et dispositifs didactiques qui y sont adaptés. [less ▲]

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See detailEvaluation results of ECHAM-HAMMOZ
Schultz, Martin; Taraborrelli, Domenico; Franco, Bruno ULg et al

Conference (2016, March 16)

Detailed reference viewed: 28 (4 ULg)
See detailSingle-Molecule Force spectroscopy on synthetic helical Nanoarchitectures
Devaux, Floriane ULg; Li, Xuesong; Huc, Ivan et al

Conference (2016, March 16)

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See detailCharacterization of the impact of tillage and nitrogen fertilization on the root development of a winter wheat crop by use of NIR hyperspectral imaging combined to chemometrics
Fraipont, Guillaume ULg; Eylenbosch, Damien ULg; Fernández Pierna, Juan Antonio et al

Poster (2016, March 16)

The objective of this study is to characterize the impact of tillage management and nitrogen fertilization on the root system development of a winter wheat crop. To reach this objective, an innovative ... [more ▼]

The objective of this study is to characterize the impact of tillage management and nitrogen fertilization on the root system development of a winter wheat crop. To reach this objective, an innovative root quantification method that combines NIR hyperspectral imaging (NIR-HSI) and chemometric tools will be applied. [less ▲]

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See detailNursing student’s perception of the educational efficiency between two strategies of education: Problem Based Learning and the High-Fidelity Simulation.
Servotte, Jean-Christophe ULg; Guillaume, Michèle ULg

Conference (2016, March 16)

Introduction: The teaching’s evolution in nursing education has to answer the challenge to stimulate the student’s skills development. According to literature review, it’s necessary to compare High ... [more ▼]

Introduction: The teaching’s evolution in nursing education has to answer the challenge to stimulate the student’s skills development. According to literature review, it’s necessary to compare High-Fidelity Simulation (HFS) with other pedagogical methods. Furthermore, the comparison with Problem Based Learning (PBL) was not studied yet. Methods: Two indicators were evaluated : student satisfaction self-confidence. For this, two validated scales were used : Student Satisfaction Learning Scale and Self-Confidence in Learning Using Simulations Scale. 141 nursing’s students were involved in the study. They were exposed to the two pedagogical methods (PBL and HFS). The experience was organized according a complete cross plan. Results: The results demonstrated a higher level of the student’s confidence and the student’s satisfaction in learning for the HFS compare to PBL. Carry-over effects were study. It was concerning the teaching style (questions 3 and 5) as well as the varieties of educational tools (questions 2 and 4). The perception of the value of the PBL during the second period was systematically lower while the score obtained for the HFS for the two periods remains almost identical. Conclusion: A clear superiority of the HFS compared with the PBL is perceived by the students. This result seems to open new opportunities with the HFS method in the education nursing student. Nevertheless, research must be conducted in order to better understand the value of this new pedagogic approach. [less ▲]

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See detailFoot identification from digital 3D models of lion tracks and paws
Marchal, Antoine ULg; Lejeune, Philippe ULg; De Bruyn, Nico

Conference (2016, March 15)

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See detailGel Beads to Investigate Sedimentation
Leleu, David ULg; Pfennig, Andreas ULg

Conference (2016, March 14)

Separation of liquid-liquid dispersions with multiple phases involves different interactions between the different dispersed species present in the system, which makes it difficult to predict e.g. the ... [more ▼]

Separation of liquid-liquid dispersions with multiple phases involves different interactions between the different dispersed species present in the system, which makes it difficult to predict e.g. the separation behaviour. Nevertheless such systems are relevant in chemical engineering e.g. for systems involving gas bubbles and simultaneously solid particles like in a fermentation broth. Models for describing the sedimentation behaviour as a basis for settler design are available in principle but have not been systematically validated for variation in size-distribution and e.g. density differences between the various species in the system. Thus, to design technical separation equipment, the separation process has to be better understood, which requires the study of the sedimentation as a first step. This project is focused on the interactions which may occur between each species during the sedimentation e.g. the effect on sedimentation of descending particles when they meet ascending drops. However, a proper study of the sedimentation with fluid phases is difficult due to other phenomena occurring simultaneously, e.g. coalescence. To overcome this issue, the use of gel beads is proposed, which due to their solid interface cannot coalesce. In addition, it is easy to define their parameters which are the density, the hardness and the size distribution. Besides, they can also be preserved during an extended period of time, experiments can thus be reproduced many times with identical beads. During the project, gel beads are designed with different particle size distributions and with different densities. Different batches of the produced gel beads will be mixed to simulate systems with different dispersed phases discriminated via density and different size distributions. With these multiple dispersed phases Experiments will be performed in a settling cell in order to evaluate the overall sedimentation velocity at certain hold up. Simultaneously a new method for measurement of local hold-up profile in the dispersion is tested, which allows hold-up measurement even in opaque systems. Finally sedimentation models found in the literature are compared and adapted to experimental results for predict the sedimentation of systems which involve different dispersed phases. In the presentation the new hold-up measurement will be presented together with an error analysis, experiments on the sedimentation of multiple dispersed phases and the model evaluation will be presented. [less ▲]

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See detailGetting on Board but How? Conflicting Perspectives on the Role of the Social Sciences and Humanities in Radiation Protection
Van Oudheusden, Michiel ULg; Rossignol, Nicolas ULg; Perko, Tanja et al

Conference (2016, March 14)

In Europe, science research policy is predicated on the understanding that science and technology (S&T) serve societal needs. Accordingly, European Framework Programs urge scientists and technologists to ... [more ▼]

In Europe, science research policy is predicated on the understanding that science and technology (S&T) serve societal needs. Accordingly, European Framework Programs urge scientists and technologists to give due attention to societal and ethical aspects of S&T, and to engage with social scientists and humanists when doing research and reaching out to society. Starting from these policy prescriptions and from invitations from befriended life scientists to "get on board," we explore the terms of our involvement as social scientists and humanists in a European Joint Program on radiation protection research (EJP-CONCERT). We illuminate recurring tensions between instrumental, normative, and substantive perspectives on the role of the social sciences and humanities (SSH) in radioprotection research and nuclear S&T. Our aim is to shed light on the controversial and contingent nature of integrating SSH into nuclear S&T, as actors articulate divergent assumptions and expectations about SSH and society. These expectations pertain to the value of SSH research for S&T, issues of trust and legitmacy, and different perspectives on risk and uncertainty. By rendering these tensions explicit we seek to probe the implications for SSH of developing a separate SSH Strategic Research Agenda (SRA) within radiation protection research. [less ▲]

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See detailOpening risk gouvernance with a vigilance system: lessons learned from the Blue Tongue Virus outbreak in 2006
Fallon, Catherine ULg

Conference (2016, March 14)

This contribution results from a field research by a multidisciplinary group of veterinary and political scientists and gives an analyses of the transformations of an epidemiosurveillance governance ... [more ▼]

This contribution results from a field research by a multidisciplinary group of veterinary and political scientists and gives an analyses of the transformations of an epidemiosurveillance governance system dedicated to animal diseases, when confronted to new emerging threats in the wake of global changes (Fallon et al., in Vertigo 12(3) 2012) . The research field refers to the emergence of bluetongue virus serotype 8 in 2006 in Belgium and it mobilises the results of a survey based on Delphi method involving relevant public servants and scientists, which showed that most of the means proposed by the authorities are based on the logic of known risk management. However we can identify attempts for renewal and organisational learning, especially with the proposal of a new vigilance system, which allows open discussion and reporting through the decision process. In terms of prevention and anticipation of the adverse event), these changes are intended to accommodate the surveillance system reactivity against uncertain and unforeseen events. We question the problems faced by this transformation and its potential for enriching and reconfiguring the conceptualisation of risk management which is currently dominant in the sector. Finally the article identifies two drivers for change in the governance network : by admitting the persistence of unavoidable cognitive uncertainty and by recognizing the importance for opening up arenas of expert knowledge. [less ▲]

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See detailThe roads of colouring materials: from sources to residues
Pradeau, Jean-Victor; Dayet, Laure; Salomon, Hélène ULg

Conference (2016, March 11)

Economic systems and social relationships gain an increasing complexity in prehistoric periods. Despite their symbolic value and their informative potential in these issues, colouring materials (“ochre” ... [more ▼]

Economic systems and social relationships gain an increasing complexity in prehistoric periods. Despite their symbolic value and their informative potential in these issues, colouring materials (“ochre”, iron oxi(hydrxi)des, cinnabar, etc.) had received scant attention compare to obsidian, flint, metals or igneous rocks. Since the 2000’s, trace elemental analysis (PIXE, XRF, INAA, ICP-MS) and petrographic studies give keys to collect gitological and sourcing data. This methodology has recently improved quantitative knowledge on colouring material’s acquisition modalities and on global technic system itself. Contrasting situations are indeed highlight: archaeological corpus may consist of several raw colouring materials, unequally shared, providing from site range, close diffusion area or far diffusion area. Furthermore, the status of the different geomaterials, the diffusion modalities – direct acquisition, direct or indirect exchanges – and the identity of exporters, transporters and receivers (if any) stay unclear. Two main topics should liven up this session: a fruitful debate on different methodologies depending on geographical contexts and diachronic revue of colouring material procurement through the lens of cultural contexts and site’s status. [less ▲]

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See detailAgeism and communication in oncology
Schroyen, Sarah ULg; Adam, Stéphane ULg; Marquet, Manon ULg et al

Poster (2016, March 11)

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See detailThe Macroeconomics of PAYG Pension Schemes in an Ageing Society
Artige, Lionel ULg

Conference (2016, March 10)

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See detailTransient neonatal diabetes mellitus due to paternal uniparental disomy of chromosome 6.
FUDVOYE, Julie ULg; Farhat, Khaldoun; Nicolescu, Ramona

Conference (2016, March 10)

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See detailL'ENMG...c'est le pied
WANG, François-Charles ULg

Conference (2016, March 10)

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See detailIntroduction au séminaire
Francois, Jeromine ULg; Regibeau, Julien ULg

Conference (2016, March 09)

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See detailSpecialization SIAMU : past, present and future
Servotte, Jean-Christophe ULg

Conference (2016, March 08)

Présentation de l'histoire de la spécialisation SIAMU avec un focus sur la simulation.

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Peer Reviewed
See detailMOOCs in business administration - An overview of assessment practice
Gherib, Camelia; Dujardin, Jean-Marie ULg; Verpoorten, Dominique ULg

in Proceedings of the Conference of the European Association for Practitioner Research on Improving Learning (EAPRIL) 2015, Issue 2 (2016, March 07)

The study explores 31 MOOCs in the field of business administration, equipped with a conceptual framework documenting 18 facets of assessment design. As a second step, the data collected on 3 MOOCs about ... [more ▼]

The study explores 31 MOOCs in the field of business administration, equipped with a conceptual framework documenting 18 facets of assessment design. As a second step, the data collected on 3 MOOCs about assessment is submitted to university members in charge of external courses accreditation procedures in order to ascertain its possible influence on their decision to credit a MOOC or not. Main results indicate that, a) the typical profile of the assessment procedure for MOOCs in business administration is: QCM-based, automatic, continuous, individual, product-centred, standardized, b) secure ways (proctoring, test-centres) to warrant learners’ identity for the tests can already be found in some MOOCs of this field, and c) concerns of course accreditors bear first and foremost on these student authentication aspects. [less ▲]

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See detailThe Many AUrorae of Jupiter : Auroral Ffilaments, Flares, Transient features of the main oval, Swirls, Polar dawn spots, Injection signatures and Satellite footprints
Bonfond, Bertrand ULg

Conference (2016, March 07)

The presentation is a review of the many features of the Jovian aurorae in the frame of the imminent arrival of the Juno spacecraft around Jupiter, with a special focus on the most recent results.

Detailed reference viewed: 4 (0 ULg)
Peer Reviewed
See detailCardio-pulmonary mechanics and minimal modelling in critical care
de Bournonville, Sébastien; Pironet, Antoine ULg; Desaive, Thomas ULg et al

in 14th Belgian Day on Biomedical Engineering (2016, March 04)

Detailed reference viewed: 14 (1 ULg)
Peer Reviewed
See detailPropositions pour penser la notion d'erreur en photographie
Havelange, Carl ULg

Conference (2016, March 04)

Detailed reference viewed: 16 (0 ULg)
Peer Reviewed
See detailParameter Correlation Analysis in Four Mathematical Models of Left Ventricular Relaxation
Pironet, Antoine ULg; MORIMONT, Philippe ULg; Dauby, Pierre ULg et al

in 14th Belgian Day on Biomedical Engineering (2016, March 04)

Detailed reference viewed: 15 (2 ULg)
See detailCardio-pulmonary mechanics and minimal modelling in critical care
de Bournonville, Sébastien; Pironet, Antoine ULg; Desaive, Thomas ULg et al

Poster (2016, March 04)

Detailed reference viewed: 10 (1 ULg)
Peer Reviewed
See detailRepeated Behavioral Assessments in Patients with Disorders of Consciousness
Wannez, Sarah ULg; Annen, Jitka ULg; Aubinet, Charlène ULg et al

Conference (2016, March 04)

The Coma Recovery Scale Revised (CRS-R) is considered as the most sensitive scale to assess patients with disorders of consciousness (DOC). Guidelines recommend repeated assessments because patients might ... [more ▼]

The Coma Recovery Scale Revised (CRS-R) is considered as the most sensitive scale to assess patients with disorders of consciousness (DOC). Guidelines recommend repeated assessments because patients might suffer from consciousness fluctuations, but it is not specified how many assessments are needed. The present study included 131 patients with DOC. They have been assessed at least 6 times during a 14-days period with the CRS-R. Results show that 5 CRS-R assessments are needed to reach a reliable diagnosis, and that all the CRS-R subscales are influenced by consciousness fluctuations. We here showed that consciousness fluctuations influence the behavioral diagnosis, and that 5 assessments within a short period of time are needed to get a reliable clinical diagnosis. [less ▲]

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See detailEuthanasie et don d'organes
DETRY, Olivier ULg

Conference (2016, March 04)

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See detailMetamorphosing cultural patterns: Cassirer in the steps of Warburg on Culture Theory
Hagelstein, Maud ULg

Conference (2016, March 03)

My argument stems from a reading of the fifth study in Cassirer’s The Logic of the Cultural Sciences (1942), devoted to the “Tragedy of Culture.” I contend that this fifth study resolves an observable ... [more ▼]

My argument stems from a reading of the fifth study in Cassirer’s The Logic of the Cultural Sciences (1942), devoted to the “Tragedy of Culture.” I contend that this fifth study resolves an observable indecision in Cassirer’s position on cultural productions: to lead man toward greater happiness and freedom, should one strive to uphold traditional forms, or should one abandon old models and create new ones? I believe that Cassirer’s consideration of art historian Aby Warburg’s works (1866-1929) constitutes a defining moment in understanding his answer to that question. This fifth study illustrates the profound impact of Warburg’s model for understanding culture on Cassirer’s philosophy. Contrary to the claims of some exegetes, Cassirer and Warburg’s theoretical positions on the matter are very close. Cassirer’s treatment of the reception of artistic forms (he argues that form reception is never merely a passive act) follows, point by point, Warburg’s theory of the survival (Nachleben) of artistic motifs. [less ▲]

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See detailRelative positioning with Galileo E5 AltBOC code measurements
Deprez, Cécile ULg

Conference (2016, March 03)

Depuis une dizaine d’années, l’Europe développe son propre système de positionnement par satellites (ou Global Navigation Satellites System (GNSS) en anglais), connu sous le nom de Galileo. À la pointe de ... [more ▼]

Depuis une dizaine d’années, l’Europe développe son propre système de positionnement par satellites (ou Global Navigation Satellites System (GNSS) en anglais), connu sous le nom de Galileo. À la pointe de la technologie, les horloges atomiques embarquées à bord de ses satellites ainsi que les signaux transmis par ces derniers sont extrêmement prometteurs dans beaucoup de domaines. Bien que toujours en phase de test à l’heure actuelle, ce système a déjà conduit à de premières mesures, notamment en matière de positionnement. Parmi ces nouvelles technologies, un signal en particulier semble très prometteur : Galileo E5, aussi appelé Galileo E5a+b ou encore Galileo E5 AltBOC. Ce signal permet d’effectuer des mesures de code et de phase plus précises. Il est également moins sensible au multi-trajet. Grâce à ses caractéristiques innovantes, Galileo E5 devrait permettre d’estimer des positions avec une précision supérieure à tous les autres signaux utilisés aujourd’hui. Une étude comparative des positions estimées avec les systèmes GPS (américain) et Galileo (européen) sur leurs différentes fréquences émises (GPS L1, GPS L2, GPS L5 pour GPS et Galileo E1, Galileo E5a, Galileo E5b et Galileo E5 AltBOC pour Galileo) a été menée dans ce mémoire. Pour ce faire, une combinaison d’observations appelée double différence (DD) est utilisée sous différentes configurations (ligne de base nulle (ZB), courte (SB) et moyenne (MB)) de récepteurs GNSS. Les récepteurs utilisés appartiennent à l’Université de Liège (2 récepteurs Trimble NetR9, 1 récepteur Septentrio XS et un récepteur Septentrio X4). Il ressort de cette étude que Galileo E5 AltBOC présente les observations les plus précises (en ZB, toutes sources d’erreurs éliminées). L’analyse démontre également qu’une précision de l’ordre de quelques décimètres sur la position à déterminer peut être atteinte avec les codes transmis par le signal Galileo E5, et ce jusqu’à 25 kilomètres de distance. [less ▲]

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See detailSalon de la géomatique F.I.G. 2016 - Saint-Dié
Donnay, Jean-Paul ULg

Conference (2016, March 03)

Le Festival International de la Géographique (FIG) est organisé depuis 1990 à Saint-Dié-des-Vosges. Il accueille chaque année quelque 50.000 visiteurs et rassemble tant les spécialistes internationaux et ... [more ▼]

Le Festival International de la Géographique (FIG) est organisé depuis 1990 à Saint-Dié-des-Vosges. Il accueille chaque année quelque 50.000 visiteurs et rassemble tant les spécialistes internationaux et que les simples amateurs de culture et d’animation. Conférences, débats, tables rondes, cafés géographiques, expositions, foire du livre, salon de la géomatique, films… tout dans la ville et durant 3 jours est consacré – gratuitement – à la présentation des dernières découvertes de la recherche scientifique en géographie. Chaque année, un pays invité est à l’honneur. En 2016, c’est la Belgique ; de sorte que les chercheurs, les enseignants et les entreprises publiques et privées belges sont spécialement invités à participer à cette manifestation. La présentation faite durant la journée BeGeo du 3 mars à Bruxelles aura pour but de présenter les conditions de participation et d’inviter les partenaires belges au Salon de la Géomatique organisé durant le Festival International de la Géographie du 30 septembre au 2 octobre 2016. [less ▲]

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Peer Reviewed
See detailAnticoherence of spin states with point-group symmetries
Baguette, Dorian ULg; Damanet, François ULg; Giraud, Olivier et al

Poster (2016, March 02)

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana ... [more ▼]

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana represen- tation of spin states in terms of points on the unit sphere, we analyze the consequences of a point-group symmetry in their arrangement on the quantum properties of the corresponding state [1]. We focus on the identi cation of anticoherent states (for which all reduced density matrices in the symmetric subspace are maximally mixed) associated with point-group-symmetric sets of points. We provide three di erent characterizations of anticoherence and establish a link between point symmetries, anticoherence, and classes of states equivalent through stochastic local operations with classical communication. We then in- vestigate in detail the case of small numbers of qubits and construct in nite families of anticoherent states with point-group symmetry of their Majorana points, showing that anticoherent states do exist to arbitrary order. [1] D. Baguette et al., Phys. Rev. A 92, 052333 (2015). [less ▲]

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See detailReversal of Long-Term Trends in Ethane Identified from the Global Atmosphere Watch Reactive Gases Measurement Network
Helmig, Detlev; Buchmann, Brigitte; Carpenter, Lucy et al

Poster (2016, March 02)

Reactive gases play an important role in climate and air pollution issues. They control the self-cleansing capability of the troposphere, contribute to air pollution and acid deposition, regulate the ... [more ▼]

Reactive gases play an important role in climate and air pollution issues. They control the self-cleansing capability of the troposphere, contribute to air pollution and acid deposition, regulate the lifetimes and provide tracers for deciphering sources and sinks for greenhouse gases. Within GAW, the focus is placed on long-term, high-quality observations of ozone (O3), carbon monoxide (CO), volatile organic compounds (VOC), nitrogen oxides (NOx), and sulfur dioxide (SO2). More than 100 stations worldwide carry out reactive gases measurements with data reported to two World Data Centers. The reactive gases program in GAW cooperates The WMO GAW Reactive Gases Program with regional networks and other global monitoring initiatives in order to attain a complete picture of the tropospheric chemical composition. Observations are being made by in-situ monitoring, measurements from commercial routine air-crafts (e.g. IAGOS), column observations, and from flask sampling networks. Quality control and coordination of measurements between participating stations are a primary emphasis. GAW reactive gases data in rapid delivery mode are used to evaluate operational atmospheric composition forecasts in the EU Copernicus Atmospheric Monitoring Service. Oversight of the program is provided by GAW-WMO coordinated Reactive Gases Scientific Advisory Committee (RG-SAG). [less ▲]

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See detailLe manuel : pourquoi ? comment ?
Pochet, Bernard ULg

Conference (2016, March 01)

The aim of this communication is to present the objective the tools used to perform, meet objectives and overcome technical constraints

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See detailEvaluer les connaissances et savoir-faire en matière de recherche d’informations scientifiques : comment faire avec de grands groupes d’étudiants en bachelier ?
Vandenput, Sandrina ULg; Crahay, Vinciane ULg; Piazza, Aurélie ULg et al

Conference (2016, March 01)

Au terme du cours consacré à la recherche d’informations scientifiques - au programme des bacheliers de la Faculté de Médecine vétérinaire et de la Faculté de Psychologie, Logopédie et des Sciences de ... [more ▼]

Au terme du cours consacré à la recherche d’informations scientifiques - au programme des bacheliers de la Faculté de Médecine vétérinaire et de la Faculté de Psychologie, Logopédie et des Sciences de l’Éducation (Université de Liège) - les étudiants doivent avoir une vue d’ensemble de la publication scientifique et être capables de (i) mener de manière autonome une recherche d’informations et (ii) de citer correctement leurs sources en respectant des normes bien précises lors de la rédaction de documents. L’évaluation de ce cours est contraignante car il s’agit de cohortes d’étudiants de plus en plus grandes (> 300 étudiants par cursus). Comment évaluer les connaissances ainsi que les savoir-faire de grands groupes d’étudiants ? Jusqu’alors l’examen se composait de questions ouvertes et nécessitait que chaque étudiant ait à sa disposition un ordinateur connecté à Internet. Cette méthode requérait une logistique importante avant et pendant l’examen ainsi que des semaines de correction. Plusieurs alternatives à cette évaluation ont alors été envisagées : travail individuel, travail de groupe, questionnaire à choix multiple… mais elles ne répondaient pas aux exigences fixées par les compétences à évaluer. La piste retenue pour cette nouvelle année académique reste contraignante du point de vue organisationnel (ordinateur pour chaque étudiant) mais permet une correction standardisée, automatisée, fiable et rapide. En effet, le questionnaire combine désormais des questions à choix multiple (QCM ; jusqu’à 9 propositions de réponses) et des questions à choix large (QCL ; jusqu’à 999 propositions). Le QCL présente l’avantage d’être proche de l’évaluation à l’aide de questions ouvertes sans les désavantages de la correction. Nous proposons de présenter ce dispositif évaluatif ainsi que ses avantages et inconvénients par rapport à d’autres méthodes d’évaluation. [less ▲]

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Peer Reviewed
See detailClassifying simulated wheat yield responses to changes in temperature and precipitation across a european transect
Fronzek, S.; Pirttioja, N.; Carter, T. R. et al

Conference (2016, March)

Detailed reference viewed: 24 (9 ULg)
Peer Reviewed
See detailInfection expérimentale de porcs, par voie intraveineuse ou orale, avec une souche du virus de l’hépatite E (HEV) de sanglier, une souche de HEV porcine et une souche de HEV de sanglier préalablement passée en modèle porcin
Thiry, Damien ULg; Rose, Nicolas; Mauroy, Axel ULg et al

Poster (2016, March)

La transmission zoonotique du HEV est particulièrement mise en cause dans les pays développés dans lesquels la transmission via les eaux usées est beaucoup moins fréquente que dans les pays en voie de ... [more ▼]

La transmission zoonotique du HEV est particulièrement mise en cause dans les pays développés dans lesquels la transmission via les eaux usées est beaucoup moins fréquente que dans les pays en voie de développement. Des séroprévalences élevées sont observées chez certaines espèces animales dans plusieurs pays européens. Cette étude a porté sur la transmission potentielle au porc d\'une souche de HEV provenant du sanglier (WbHEV) par inoculation intraveineuse ou par voie orale et sur l’étude des conséquences de l’infection du porc par une souche de WbHEV, une souche de WbHEV précédemment passée chez le porc et une souche porcine de HEV après inoculation orale. Tout d\'abord, une infection par voie intraveineuse a été réalisée au cours de laquelle cinq porcelets ont été répartis en deux groupes. Le premier était constitué de trois porcs inoculés avec du WbHEV et le second, de deux porcs inoculés avec un foie de porc négatif envers le HEV. Tous les porcs ont été euthanasiés et autopsiés 8, 9 et 10 jours après l’inoculation. Cette première expérience avait pour objectif d’obtenir suffisamment de virus en vue de réaliser les inoculations par voie orale. Elle a également permis d’étudier l’infectivité d’une souche de HEV-3 provenant du sanglier chez le porc. Ensuite, une infection par voie orale a été réalisée sur 12 porcelets répartis en 4 groupes inoculés respectivement avec une souche de WbHEV, une souche de WbHEV précédemment passée chez le porc, une souche porcine de HEV et un foie de porc HEV négatif. Cette expérience a duré 56 jours. Les échantillons récoltés ont ensuite été analysés par qRT-PCR, ELISA, Western blot et histopathologie. Le nombre de porcs virémiques était plus faible après infection orale qu’après inoculation intraveineuse. Ce résultat contraste avec la présence du HEV dans les matières fécales des porcs au cours des deux expériences. Les résultats montrent également une propagation du virus dans différents organes après inoculation intraveineuse, mais pas après inoculation par voie orale. Cette étude fournit la première preuve expérimentale de la propagation précoce du virus dans l\'organisme après infection intraveineuse avec une souche de HEV provenant du sanglier et montre qu’une telle souche pourrait être naturellement transmise entre les sangliers et les porcs, mais aussi entre porcs et donc survivre dans la population porcine. [less ▲]

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See detailOrphan Black and Literature
Guesse, Carole ULg

Conference (2016, March)

Detailed reference viewed: 29 (2 ULg)
See detailDynamical thermalization in Bose-Hubbard systems
Schlagheck, Peter ULg; Shepelyansky, Dima L.

Conference (2016, March)

A bosonic many-body system can exhibit the Bose-Einstein distribution in its single-particle eigenstates not only if it is coupled to a heat and particle reservoir, but also if it is subject to a two-body ... [more ▼]

A bosonic many-body system can exhibit the Bose-Einstein distribution in its single-particle eigenstates not only if it is coupled to a heat and particle reservoir, but also if it is subject to a two-body interaction of moderately low strength which couples the single-particle eigenstates with each other. We numerically verify this dynamical thermalization conjecture within disordered Bose-Hubbard rings of finite size whose parameters are chosen such that the dynamics of the system can be expected to be ergodic [1]. This allows one to associate with each many-body eigenstate of the Bose-Hubbard system well-defined (positive or negative) values for the effective temperature and the effective chemical potential which depend on the energy per particle of the eigenstate under consideration [1]. With this information one can then predict the populations of single-particle eigenmodes within each many-body eigenstate of the system according to the Bose-Einstein distribution, without knowing more details about the quantum dynamics of the many-body system. [less ▲]

Detailed reference viewed: 18 (3 ULg)
See detailReturn words and factor complexity
Leroy, Julien ULg

Conference (2016, March)

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See detailBois, brique et fer : Approche multi-disciplinaire de la charpente de l'église Notre-Dame du Sablon, Bruxelles (RBC)
CREMER, Sarah; FRAITURE, Pascale; Hoffsummer, Patrick ULg et al

in Archaeologia Mediaevalis (2016, March), 39

Detailed reference viewed: 22 (5 ULg)
See detailCarbon dioxide and vegetable oil for the synthesis of bio-based polymer precursors, theoretical study of the organocatalyzed synthesis of non-isocyanate polyurethanes
Alves, Margot ULg; Jérôme, Christine ULg; Tassaing, Thierry

Conference (2016, March)

Non-isocyanate polyurethanes (NIPUs) represent a green alternative to the classical synthesis route of polyurethanes involving toxic isocyanates. This “greener” approach based upon renewable feedstocks ... [more ▼]

Non-isocyanate polyurethanes (NIPUs) represent a green alternative to the classical synthesis route of polyurethanes involving toxic isocyanates. This “greener” approach based upon renewable feedstocks and carbon dioxide consists in a two-step reaction. In a first step, carbonated vegetable oils are obtained using an appropriate catalyst by the chemical fixation of CO2 onto vegetable oils formerly epoxidized. Finally, the ring-opening polymerization (ROP) of the carbonated vegetable oil by a diamine provides hydroxy urethanes. In this las step, some organocatalysts have been recently proposed that allows achieving good conversion rates in particular in the case of aromatic diamines. However, the activation mechanism of these organocatalysts is not fully elucidated. In this context, the aim of the present project relies on the theoretical study of a model reaction using DFT calculations. Bicyclic guanidine based catalysts, 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) and 7-methyl-TBD (MTBD), were investigated as catalysts for the reaction between propylene carbonate and aliphatic or aromatic amines. The structural ability of TBD to simultaneously give and receive protons was highlighted by the detailed mechanism investigation. The bifunctional activity of TBD significantly reduces the Gibbs energy of the reaction and allows understanding its higher efficiency compared to its methyl counterpart (MTBD). [less ▲]

Detailed reference viewed: 43 (2 ULg)
Peer Reviewed
See detailDevelopment of a translation stage for in situ non-invasive analysis and high resolution imaging
Strivay, David ULg; Clar, Mathieu ULg; Rakkaa, Saïd ULg et al

Poster (2016, March)

Non-invasive imaging techniques and analytical instrumentation for cultural heritage object studies have undergone a tremendous development over the last years. Many new miniature and/or handheld systems ... [more ▼]

Non-invasive imaging techniques and analytical instrumentation for cultural heritage object studies have undergone a tremendous development over the last years. Many new miniature and/or handheld systems have been developed and optimized. Nonetheless, these instruments are usually used with a tripod or a manual position system. This is very time consuming when performing point analysis or 2D scanning of a surface. The Centre Européen d’Archéométrie (CEA) has build a translation system made of pluggable rails of 1 m long with a maximum length and height of 3 m. Three motors embedded in the system allow the platform to be moved along these axis, toward and backward from the sample. The rails hold a displacement system, providing a continuous movement. Any position can be reached with a reproducibility of 0.1 mm. The displacements are controlled by an Ethernet connection through a laptop computer running a multiplatform homemade software written in JAVA. This software allows a complete control over the positioning using a simple, unique, and concise interface. Automatic scanning can be performed over a large surface of 3 meters on 3 meters. The Ethernet wires provide also the power for the different motors and, if necessary the detection head. The platform has been originally designed for a XRF detection head (with its full power alimentation) but now can accommodate many different systems like IR reflectography, digital camera, hyperspectral camera, Raman probes, etc. The positioning system can be modified to combine the acquisition software of the imaging or analytical techniques and the positioning software. [less ▲]

Detailed reference viewed: 47 (6 ULg)
See detailBad News in Service Encounters: Ideas and Insights
Delcourt, Cécile ULg; Gremler, Dwayne

Conference (2016, March)

Detailed reference viewed: 38 (1 ULg)
Peer Reviewed
See detailMobiliser la culture du pays d’origine, un défi pour l’intégration des migrants?
Mescoli, Elsa ULg; Gsir, Sonia ULg

Conference (2016, March)

La culture constitue pour les migrants et leurs pays d’origine un moyen de maintenir des liens réciproques après la migration. Mais quels sont les enjeux de la mobilisation de la culture d’origine pour ... [more ▼]

La culture constitue pour les migrants et leurs pays d’origine un moyen de maintenir des liens réciproques après la migration. Mais quels sont les enjeux de la mobilisation de la culture d’origine pour l’intégration des migrants dans leurs nouveaux pays de résidence ? Cette présentation analyse le déploiement de la culture du pays d’origine à trois niveaux : celui des pratiques quotidiennes des migrants, des politiques d’intégration et de diaspora et enfin, le niveau des associations, en particulier les centres culturels établis en Europe par les pays d’origine des migrants. Les pratiques culturelles des migrants et les actions et institutions culturelles mises en place par les pays d’origine sont confrontées au cadre légal européen en matière de diversité culturelle mais aussi aux politiques et discours sur l’intégration des migrants. La perspective à la fois anthropologique et sociologique adoptée révèle les processus de domination culturelle qui sont à l’œuvre. Elle permet aussi de questionner l’idée d’identité culturelle en montrant le dynamisme qui caractérise les cultures mais aussi la créativité des communautés locales dans un environnement globalisé. Finalement, on constate qu’une variété de facteurs est en jeu dans les processus d’intégration des migrants, que les dynamiques de la culture elle-même déterminent des appartenances multiples et aussi que les identités se développent au sein des interactions entre cultures. Si on ne peut établir de lien causal et univoque entre les pratiques culturelles liées au pays d’origine et l’intégration des migrants dans le pays de résidence, on peut par contre se référer à la notion d’ethnicité et à sa fonction politique (Comaroff et Comaroff, 2009). [less ▲]

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See detailEstetrols’ Potential for Neuroprotection Following the injury to the Developing Brain: Preclinical Studies
Tskitishvili, Ekaterine ULg; Nisolle, Michelle ULg; Noël, Agnès ULg et al

in The 17th World Congress of Gynecological Endocrinology, Florence 2-5 March 2016 (2016, March)

Context: Hypoxic-Ischemic encephalopathy (HIE) remains a major cause of perinatal brain injury. The brain rapidly increases in size, shape and complexity during the second and third trimesters. A sentinel ... [more ▼]

Context: Hypoxic-Ischemic encephalopathy (HIE) remains a major cause of perinatal brain injury. The brain rapidly increases in size, shape and complexity during the second and third trimesters. A sentinel event in late pregnancy or the intrapartum period may have an acute profound effect on a previously neurologically intact fetus, leading to the development of (HIE). The nature of the deficits is dependent on the gestational age and severity of the insult, though it is seldom reported in preterm infants. Studies in animal models of HIE may provide important information for the development of treatment for this pathological condition. Estetrol (E4) is a recently described estrogen with four hydroxyl-groups that is synthesized exclusively during pregnancy by the human fetal liver. Objective: In this study, we evaluated E4’s neuroprotective and therapeutic potency in neonatal (in vivo) HIE model of the immature 7-day-old newborn rat. Methods: Rat pups body temperatures were examined along with their body and brain weights. Brains were studied at the level of the hippocampus and cortex. Intact cell counting and expressions of markers for neuronal early grey matter damage (microtubule-associated protein-2 (MAP-2)), neurogenesis (doublecortin (DCX)) and angiogenesis (vascular-endothelial growth factor (VEGF)) were evaluated by histo- and immunohistochemistry. The serum levels of two markers of brain damage (S100B and glial fibrillary acidic protein (GFAP)) were measured by ELISA. Results: Our results demonstrate that E4 has a significant neuroprotective and therapeutic effects. Estetrol decreases the early gray matter loss, and promotes neuro- and angiogenesis in vivo. Estetrol treatment has no effects on body weight, brain weight or body temperature. Conclusion: Taken together, E4 might become an important safe and physiological substance to treat neonatal HIE. [less ▲]

Detailed reference viewed: 26 (3 ULg)
Peer Reviewed
See detailThe bottom up innovation and entrepreneurship in smart cities, case of Indian cities
Kummitha, Rama; Crutzen, Nathalie ULg

Conference (2016, March)

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See detailDouble genetic defect in a case of congenital hypogonadotropic hypogonadism
Potorac, Iulia ULg; Pintiaux, Axelle ULg; VALDES SOCIN, Hernan Gonzalo ULg et al

in Abstract book - 17th World Congress of Gynecological Endocrinology (2016, March)

Detailed reference viewed: 30 (1 ULg)
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See detailNovel composite heterozygous mutation of the receptor for hCG and LH leading to male disorder of sexual development
Potorac, Iulia ULg; FUDVOYE, Julie ULg; GAILLEZ, Stephanie ULg et al

in Abstract book - 17th World Congress of Gynecological Endocrinology (2016, March)

Detailed reference viewed: 18 (2 ULg)
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See detailA "external" StandPoint on QMS
Massart, Sébastien ULg

Conference (2016, March)

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Peer Reviewed
See detailAntihyperglycémiants, antihypertenseurs et hypolipidémiants : comparaison des effets sur la mortalité et la morbidité cardiovasculaire chez le patient diabétique de type 2
SCHEEN, André ULg

Poster (2016, March)

Introduction : Réduire le risque de mortalité et morbidité cardiovasculaire (CV) chez le patient diabétique de type 2 (DT2) est primordial, mais les effets protecteurs semblent différents selon le mode ... [more ▼]

Introduction : Réduire le risque de mortalité et morbidité cardiovasculaire (CV) chez le patient diabétique de type 2 (DT2) est primordial, mais les effets protecteurs semblent différents selon le mode d’intervention pharmacologique étudié. Patients et méthodes : Les données de mortalité (totale et CV) et morbidité (infarctus du myocarde ou IDM, accidents vasculaires cérébraux ou AVC) rapportées (réduction du risque relatif) dans les essais ayant testé un traitement anti-hyperglycémiant sont comparées avec les résultats publiés dans deux méta-analyses concernant les hypolipidémiants et les anti-hypertenseurs consacrées au DT2. Résultats : Les antihypertenseurs réduisent les IDM (-12%) et la mortalité globale (-13%) de façon comparable, et diminuent davantage les AVC (-27%). Les hypolipidémiants diminuent davantage les IDM (- 22%) et les AVC (-21%) que la mortalité globale (-9%) (ou la mortalité CV : - 13%). Les données concernant les antihyperglycémiants diffèrent considérablement selon les médications testées. L’insuline et les sulfamides (UKPDS) réduisent plus les IDM (- 21%) que la mortalité totale (-8%), mais augmentent les AVC (+ 14%). La metformine (UKPDS) réduit, de façon comparable, les IDM (-39%), les AVC (-41%) et la mortalité totale (-36%). La pioglitazone (PROactive) diminue davantage les IDM (-17%) et les AVC (-19%) que la mortalité (-4%). Les gliptines (combinaison de SAVOR TIMI 53, EXAMINE, TECOS) ont montré des effets globalement neutres sur la mortalité totale (0%), les IDM (-2%) et les AVC (-1%). L’empagliflozine (EMPA-REG OUTCOME) se singularise par un effet favorable nettement plus marqué sur la mortalité totale (-32 %) et CV (- 38%) que sur les IDM (-13%) ou les AVC (+18%). Conclusion : Les discordances observées suggèrent l’implication de mécanismes protecteurs différents selon les interventions testées. EMPA-REG OUTCOME, le seul essai démontrant un effet plus marqué sur la mortalité que sur les événements CV, suggère un mécanisme propre de l’inhibiteur des SGLT2. [less ▲]

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See detailLe sensible chez Franz Brentano
Gauvry, Charlotte ULg

Conference (2016, March)

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Peer Reviewed
See detailDes pratiques enseignantes qui font obstacle au rôle des modèles dans la construction des savoirs scientifiques. 2. Le cas de la discipline scolaire "histoire de l'art"
Heins, Pascal ULg

Conference (2016, March)

Dans une perspective comparatiste, des didacticiens de plusieurs disciplines (mathématiques, physique, chimie, biologie, histoire de l’art) ont étudié des pratiques enseignantes faisant obstacle au rôle ... [more ▼]

Dans une perspective comparatiste, des didacticiens de plusieurs disciplines (mathématiques, physique, chimie, biologie, histoire de l’art) ont étudié des pratiques enseignantes faisant obstacle au rôle des modèles dans la construction des savoirs scientifiques. Leur réflexion croisée les a amenés à considérer des niveaux élevés de l’échelle de co-détermination didactique de Chevallard (2012) pour identifier des indicateurs d’une certaine forme de positivisme empirique dans l’épistémologie spontanée des enseignants. Cette posture s’exprime plus ou moins différemment d’une discipline à l’autre, mais le fait que les modèles et théories enseignées ont fait ou non l’objet d’une standardisation au sein de communautés scientifiques savantes déterminent fortement leur transposition didactique. De ce point de vue, l’exemple de l’histoire de l’art a joué un rôle méthodologique important permettant de contraster et de questionner les pratiques dans les autres disciplines. Ce questionnement s’inscrit dans un objectif à plus long terme qui est la reproblématisation (au sens de Orange, 2005) d’enseignements relatifs aux disciplines enseignées. [less ▲]

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