References of "Scientific congresses and symposiums"
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See detailEtude de la flore spontanée de la carrière de Loën (Belgique) pour de futures restaurations
Pitz, Carline ULg; Monty, Arnaud ULg; Piqueray, Julien et al

Conference (2015, March 04)

Afin de maximiser le potentiel de biodiversité d’une carrière en fin d’exploitation deux options s’offrent au gestionnaire : (1) laisser les espèces recoloniser spontanément le site, (2) mettre en œuvre ... [more ▼]

Afin de maximiser le potentiel de biodiversité d’une carrière en fin d’exploitation deux options s’offrent au gestionnaire : (1) laisser les espèces recoloniser spontanément le site, (2) mettre en œuvre des appuis techniques à la restauration d’écosystèmes. Une méthode hybride associant une recolonisation naturelle et une assistance technique peut également être une opportunité pour le gestionnaire. La recolonisation spontanée des carrières peut, dans certains cas, créer une mosaïque d’habitats diversifiés pour des coûts faibles par rapport à des projets de réhabilitation ou de restauration couteux. Toutefois, l’intérêt biologique des habitats issus de successions spontanées peut fortement varier d’un site à l’autre en fonction de l’historique de gestion, des conditions climatiques et édaphiques locales, de l’isolement du site dans le paysage et du pool régional d’espèces présentes. Afin d’évaluer la nécessité ou non de mise en œuvre d’une restauration active d’habitats en carrière, il est nécessaire de caractériser les habitats issus de la succession spontanée ainsi que leur valeur biologique. L’évaluation de l’intérêt biologique d’un habitat prend en compte à la fois la diversité biologique locale (diversité alpha) et l’originalité des communautés présentes par rapport à un référentiel paysager (diversité béta). Ce projet a pour objectif de caractériser la flore recolonisant spontanément les zones xériques non exploitées dans une carrière située en Belgique (Loën, en région wallonne), du point de vue de la diversité spécifique et de la fonctionnalité écologique. Les communautés végétales ont été caractérisées au sein du site de Loën (diversité alpha) et d’un ensemble d’autres carrières représentatives de la diversité des contextes géographiques des carrières calcaires en Région wallonne (diversité béta). [less ▲]

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See detailQuaternary prevention, a GP/FM construct, based on patient-doctor relationships
Jamoulle, Marc ULg; Roland, Michel; Tsoi, Gene

Poster (2015, March 04)

Story of the building of the concept of Quaternary prevention

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See detailEnabling technologies and methods for the synthesis of (bio)organic molecules
Monbaliu, Jean-Christophe ULg

Conference (2015, March 03)

We will discuss the development and implementation of continuous-flow multistep strategies for the synthesis of bio(organic) targets. Selected examples include unusual reaction conditions such as working ... [more ▼]

We will discuss the development and implementation of continuous-flow multistep strategies for the synthesis of bio(organic) targets. Selected examples include unusual reaction conditions such as working with solids in microreactors, high temperature reactions and the handling of highly reactive species. [less ▲]

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See detailRéputation scientifique et indicateurs de performance
Leclercq, Bruno ULg

Conference (2015, March 02)

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See detailLe "champ" de l'accompagnement des demandeurs d'emploi est-il un "marché" ?
Remy, Céline ULg

in Galabov, Antoniy; Rouet, Gilles (Eds.) Services publics, entreprises publiques : quelle place pour les citoyens? (2015, March 01)

Le but de ce chapitre est d’interroger le champ de l’accompagnement des demandeurs d’emploi comme étant ou non un marché conventionnel. Pour ce faire, les concepts de marché, de quasi-marché, de marché ... [more ▼]

Le but de ce chapitre est d’interroger le champ de l’accompagnement des demandeurs d’emploi comme étant ou non un marché conventionnel. Pour ce faire, les concepts de marché, de quasi-marché, de marché public et de champ sont clarifiés dans un premier temps. Pour comprendre le fonctionnement du marché de l’accompagnement, il est nécessaire dans un deuxième temps d’examiner quatre dimensions qui sont le périmètre et le financement de celui-ci mais également la sélection des opérateurs externes par les services publics de l’emploi et les stratégies développées par les différents acteurs appartenant à ce marché. L’étude de ces dimensions qui s’appuie sur trois études de cas permet de montrer la singularité du marché de l’accompagnement. [less ▲]

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See detailSpS5 - III. Matter ejection and feedback
Nazé, Yaël ULg; Che, Xiao; Cox, Nick L. J. et al

in Highlights of Astronomy, vol 16 (2015, March 01)

The last part of SpS5 dealt with the circumstellar environment. Structures are indeed found around several types of massive stars, such as blue and red supergiants, as well as WRs and LBVs. As shown in ... [more ▼]

The last part of SpS5 dealt with the circumstellar environment. Structures are indeed found around several types of massive stars, such as blue and red supergiants, as well as WRs and LBVs. As shown in the last years, the potential of IR for their study is twofold: first, IR can help discover many previously unknown nebulae, leading to the identification of new massive stars as their progenitors; second, IR can help characterize the nebular features. Current and new IR facilities thus pave the way to a better understanding of the feedback from massive stars. [less ▲]

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See detailMeasurements of air-ice CO2 fluxes over artificial sea ice emphasize the role of bubbles in gas transport
Kotovitch, Marie ULg; Moreau, Sébastion; Zhou, Jiayun et al

Poster (2015, March)

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See detailAn orphan GPCR may be mutated in patients with Cushing Disease
Correa, RR; Trivellin, G; Li, Y et al

in Abstract book - ENDO 2015 (2015, March)

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See detailIUVS dayglow analysis
Jain; Evans; Stevens et al

Conference (2015, March)

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See detailAnalysis of Martian nightglow and aurora
Stiepen, Arnaud ULg

Conference (2015, March)

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See detailSplit-Band Interferometric SAR Processing Using TanDEM-X Data
De Rauw, Dominique ULg; Kervyn, François; d'Oreye, Nicolas et al

in ESA SP-731 (2015, March)

Most recent SAR sensors use wide band signals to achieve metric range resolution. One can also take advantage of wide band to split it into sub-bands and generate several lower-resolution images, centered ... [more ▼]

Most recent SAR sensors use wide band signals to achieve metric range resolution. One can also take advantage of wide band to split it into sub-bands and generate several lower-resolution images, centered on slightly different frequencies, from a single acquisition. This process, named Multi Chromatic Analysis (MCA) corresponds to performing a spectral analysis of SAR images. Split-Band SAR interferometry (SBInSAR) is based on spectral analysis performed on each image of an InSAR pair, yielding a stack of sub-band interferograms. Scatterers keeping a coherent behaviour in each sub-band interferogram show a phase that varies linearly with the carrier frequency, the slope being proportional to the absolute optical path difference. This potentially solves the problems of phase unwrapping on a pixel-per-pixel basis. In this paper, we present an SBInSAR processor and its application using TanDEM-X data over the Nyiragongo volcano. [less ▲]

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See detailFirst results from MAVEN's Imaging UV spectrograph
Schneider; McClintock; Stewart et al

Conference (2015, March)

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See detailAlignments of quasar axes with large-scale structures
Hutsemekers, Damien ULg; Braibant, Lorraine ULg; Pelgrims, Vincent ULg et al

Poster (2015, March)

Based on measurements of optical linear polarization of quasars belonging to large groups at redshift z ~ 1.3, we found that quasar spin axes are likely parallel to their host large-scale structures ... [more ▼]

Based on measurements of optical linear polarization of quasars belonging to large groups at redshift z ~ 1.3, we found that quasar spin axes are likely parallel to their host large-scale structures (Hutsemékers et al. 2014). These observations can constrain models of the coevolution of AGN, galaxies and large-scale structures. [less ▲]

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See detailAutoimmune thyroid diseases in early childhood three case reports
GUFFINS, A; HARVENGT, Julie ULg; LUYCKX, F et al

Poster (2015, March)

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See detailX-Linked acro-gigantism (X-LAG) due to microduplications of chromosome Xq26 : A new disorder and implications for acromegaly
Trivellin, G; Daly, AF; Faucz, FR et al

in Abstract book - ENDO 2015 (2015, March)

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See detailStrain localization modelling around an underground gallery in Mol with an analysis of the contact pressure on the lining
Salehnia, Fatemeh ULg; Dizier, Arnaud; Li, Xiang Ling et al

Poster (2015, March)

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See detailCharacterization of Venom Peptides using Microfluidic Separation Techniques coupled to Mass Spectrometry (LC-MS and CE-MS)
Degueldre, Michel ULg; Delvaux, Cédric ULg; Far, Johann ULg et al

Poster (2015, March)

More than the half of the principal sub-kingdoms of the animal world contains species that produce venom whose purposes are to immobilize, kill and pre-digest the preys. These venoms represent an ... [more ▼]

More than the half of the principal sub-kingdoms of the animal world contains species that produce venom whose purposes are to immobilize, kill and pre-digest the preys. These venoms represent an exceptionally rich source of various biologically active peptides, both in their structures and their effects, which are more and more useful for human being1. Yet, the total characterization of such complex samples require advanced analytical techniques mainly due to the complexity of the sample (hundreds of compounds), the limited quantities usually available and the presence of numerous PTMs, especially disulfide bridges and specific folding. Here we present a method that combines LC and CE separation techniques coupled to mass spectrometry (MS) to characterize the peptide composition of the snake venom Naja atra. The characterization will not only focus on the toxin sequencing (LC-MS and LC-MS/MS), but will also aim at analyzing the folding of the toxins (CE-MS). To this end, native and reduced/alkylated toxins will be analyzed by both techniques. Final result targets the determination of the global hydrophobic pattern and native tridimensional folding of these strongly reticulated peptides. (1) Richard J. Lewis & Maria L. Garcia, Therapeutic potential of venom peptides. Nature Reviews Drug Discovery 2003, 2, 790-802. [less ▲]

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See detailImaging air filled porosity in sea ice cover: Implication for sea ice permeability and gas exchange at the ice-atmosphere interface
Crabeck, O,; Galley, R,; Else, B, et al

Poster (2015, March)

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See detailCortical responses to transcranial magnetic stimulation during Non-Rapid Eye Movement Sleep
Gosseries, Olivia ULg; Jaakko, Nieminen; Siclari, Francesca et al

Poster (2015, March)

Transcranial magnetic stimulation coupled to high-density electroencephalography (TMS-EEG) allows for directly and non-invasively stimulating the brain and recording the subsequent cortical response ... [more ▼]

Transcranial magnetic stimulation coupled to high-density electroencephalography (TMS-EEG) allows for directly and non-invasively stimulating the brain and recording the subsequent cortical response. Previous TMS-EEG studies have shown clear-cut differences between conscious and unconscious conditions. When subjects are unconscious, as in non-rapid eye movement (NREM) sleep early in the night (stage N3), anesthesia or coma, TMS typically triggers a stereotypical and local slow-wave response. When they are conscious, as in normal wakefulness and rapid eye movement sleep (REM) sleep, brain responses to TMS are long-lasting, widespread, complex, and differentiated. In this study, we performed TMS-EEG during NREM sleep in stage 2 (N2) and N3 on 7 healthy participants. Brain activity was recorded using a 60-channel TMS-compatible EEG and single-pulse TMS was applied (up to 285 pulses per session) on the superior parietal cortex. After each TMS session (5 to 15 sessions per night), subjects were awakened to ask for a dream report. TMS-EEG responses were analyzed using the global mean field amplitude (GMFA), the perturbational complexity index (PCI), as well as time-frequency measures. Our results show that the TMS-EEG response during N3 is larger and slower than during N2 sleep. The GMFA is higher and PCI is lower in N3 as compared to N2 sleep. Moreover, N3 recordings showed activation at lower frequency bands after TMS as compared to N2 sleep. Additionally, TMS-EEG responses vary depending on whether subjects do or do not report a dream. TMS-EEG might provide valuable information for characterizing neurophysiological fluctuations and levels of consciousness within NREM sleep. [less ▲]

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See detailPhotosynthesis-irradiance response curves revealed active sympagic communities in the Weddell Sea Winter, 2013
Rintala, J.-M.; Luhtanen, A.-M.; Enberg, S. et al

Poster (2015, March)

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See detailMAVEN IUVS observations of the aftermath of Comet Siding Spring's meteor shower
Stewart; Schneider; Plane et al

Conference (2015, March)

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See detailDesign and implementation of a ‘physical activity day’ for overweight and obese youth
Cloes, Marc ULg; DEWANDRE, Anne-Cécile ULg; LEBRETHON, Marie-Christine ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1),

This study aimed to analyze the development and implementation of an adapted physical activity day expected to underline to overweight/obese youth the role of PA and hw they could be more active in their ... [more ▼]

This study aimed to analyze the development and implementation of an adapted physical activity day expected to underline to overweight/obese youth the role of PA and hw they could be more active in their daily life. [less ▲]

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See detailMeasuring nonlinear distortions: from test case to an F-16 fighter
Vaes, Mark; Schoukens, Johan; Rolain, Yves et al

Conference (2015, March)

What are the similarities and differences between the behavior of a small vibrating test system and an F-16 fighter? To find it out, we compare measurements of the test system to measurements from the ... [more ▼]

What are the similarities and differences between the behavior of a small vibrating test system and an F-16 fighter? To find it out, we compare measurements of the test system to measurements from the bolted connection of the wing and the missile of a F-16 Fighter Falcon from the Belgian air force. These measurements were done during a ground vibration test (GVT) campaign. Essentially, the behavior of these systems match, even though the test system is only the heart of a self-study kit for nonlinear system identification and the F-16 is a complex real life mechanical structure. This clearly shows the added value of an experiment driven nonlinear educational system identification package. It provides safe small-scale toy examples for hands-on exercises that react like real systems. We believe that this practical approach lowers the gap between learning system identification concepts and applying it on real systems. [less ▲]

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See detailThe Solar Energetic Particle experiment on MAVEN: first results
Larson, Davin; Lillis; Dunn et al

Conference (2015, March)

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See detailFamily farming in a changing landscape : how activities change when forest disappears
Feintrenie, Laurène; Gillet, Pauline ULg; Garcia, Claude et al

Conference (2015, March)

In the Congo Basin forests, local communities used to live from hunting, fishing and gathering, and from slash and burn agriculture. Nowadays, few places remain isolated from the external world, and local ... [more ▼]

In the Congo Basin forests, local communities used to live from hunting, fishing and gathering, and from slash and burn agriculture. Nowadays, few places remain isolated from the external world, and local practices often have to integrate new parameters. How do family farming and forest activities evolve in a changing landscape, when forest disappears? To answer this question we selected three social and ecological systems positioned in specific places on the forest transition curve (Mather 1992), to constitute a synchronic sample of forested social and ecological system representative of the evolution of Congo Basin Forests. We conducted in 2013 and 2014 a deep analysis of family farming in 8 villages distributed in these 3 studied sites. The method crosses a systemic approach with a systematic approach: agrarian diagnoses were conducted in the three sites (Boulaud 2014; Ferlay 2014) to evaluate technical and economic performances of family farming and forest extractive activities, in parallel, census of households were conducted (Codina Llavinia 2014; Gillet et al. 2014; Lehnebach 2014) to range family activities according to their share in the family income and as subsistence means. Results were harmonized and allowed a deep understanding of the strategy of adaptation to changes of households. [less ▲]

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See detailScience policy narratives in Flanders and Wallonia: The interplay of characters and ideas
Charlier, Nathan ULg

Conference (2015, March)

Both in Europe and in the United States, scientific research and science, technology and innovation (STI) policies have undergone profound changes in the last thirty years. In the literature, these ... [more ▼]

Both in Europe and in the United States, scientific research and science, technology and innovation (STI) policies have undergone profound changes in the last thirty years. In the literature, these transitions are often framed along dichotomous lines : an 'old regime' characterized by strong public funding, independent academia and a linear conception of innovation has supposedly been replaced by a 'new regime' in which research and innovation are conceived in systemic terms, regarding their economic and societal relevance (Rip 2000). These conceptions have been criticized regarding their historical accuracy, or regarding their (un)political-reading of those evolutions (Pestre, 2003). More broadly, Nowotny has recently emphasized the fact that the political understanding of science has been black boxed in STS (Nowotny, 2014). My proposal aims at investigating the multiple political conceptions of science in a regional context: what value is attributed to science? What are its aims? How should it be organized and funded? More specifically, this paper relies on an analytical framework based on the notion of "policy narratives" for science to examine how coexisting, and sometimes competing narratives are embedded in situated discourses, policies and practices. Policy narratives include the following elements (Jones & McBeth, 2010): A context, a plot (a sequence with a beginning, a middle and an expected end: Roe, 1992), characters that have a role and intervene in the plot, and some kind of 'moral' of the story advanced as a policy solution. As narratives help actors to make sense of things and orient their actions, they are both descriptive and performative. Hence, they relate to the notion of imaginary in a very concrete sense: narrative are related to actual institutions, and emerging policy narrative can serve as rationale for change. In this paper, narratives like, e.g., the "Knowledge-based Economy", the "Grand societal Challenges", "Science, the endless Frontier", are studied. Each attribute a different public value to science: improving economic growth, tackling specific issues such as cancer or ageing population, or increasing knowledge as a good in itself. Each also propose a specific organization for the STI system, and assign a specific role to the various stakeholders (the scientists, the university authorities, policy makers, industrialists and entrepreneurs, etc.). In order to understand how these global policy narrative are locally articulated, and thereby grounded in regional STI policymaking, my research is based on interviews with a range of stakeholders in Wallonia: biotech lab leaders, members of university boards, and representatives of labor and employers' organizations in regional advisory boards. In the analysis, a particular attention is paid to the various narratives used by the stakeholders when answering broad questions, with regards to their position. More specifically, the way stakeholders depict and scenarize their own role(s) and their relations with other actors is highly political and hence should be assessed. A main thesis of the paper is that one narrative does not constitute the only resource of a (group of) actor(s). Actors refer to different narratives regarding the context and regarding the evolution they promote. [less ▲]

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See detail(In)sécurités linguistiques francophones en Belgique : du taux d’insécurité aux facteurs d’(in)sécurité
Dassargues, Alix ULg

in L'insécurité en question : défis, enjeux et perspectives (2015, March)

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See detailActors valuing science in neoliberal science regimes
Charlier, Nathan ULg; Delvenne, Pierre ULg

Conference (2015, March)

With the underlying hypothesis of a shift toward neoliberal science regimes, much work has been done to analyze the multiple transformations of science institutions and policies over the last decades (e.g ... [more ▼]

With the underlying hypothesis of a shift toward neoliberal science regimes, much work has been done to analyze the multiple transformations of science institutions and policies over the last decades (e.g. Mirowski and Sent 2008; Slaughter & Rhoades, 2004; Bruno, 2008). The trends towards privatization and commodification of science are undisputable but we argue that little attention has been paid so far to the various political conceptions of research and innovation (R&I) coexisting within neoliberal science regimes. Cognitive approaches to public policy already stressed the circular relationship between meaning and power (e.g. Muller and Surel, 1998; Roe, 1994), but neoliberal science has remained out of the scope of such analyses. Regarding R&I policies, this leads to different ways to conceive of the “value” of science, some related to preexisting institutions and narratives, and some branching out toward new cognitive resources to achieve politico-economic aims. In our proposal, we hypothesize the coexistence of at least four policy narratives which help structuring the representations and actions of scientists and policymakers when they address science as a political object: ‘science for the sake of science’, ‘science, the endless frontier (continued)’, ‘knowledge-based economy’ and ‘grand societal challenges’. Each one attributes a different value to science, proposes a specific organization for the R&I system, and addresses the relation between economy and society differently. In order to understand how these policy narratives are locally articulated, and thereby grounded in R&I policymaking, we analyze the political discourses on science at three different institutional levels (biotechnology labs, university management, science policy advisory boards) in Belgium. Our data were gathered through semi-structured interviews with key members of the institutions studied. By analyzing the interplay of policy narratives for R&I in a context of neoliberal science, we aim to contribute to a better understanding of the ways science is valued at different levels. [less ▲]

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See detailIsolation of cultivable viruses from Antarctic wintertime sea ice
Luhtanen, A.-M.; Bamford, D.; De Jong, J. et al

Poster (2015, March)

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See detailA two-surface viscoplastic model for saturated clays
Hong, P.Y.; Cui, Y.J.; Pereira, J.M. et al

Poster (2015, March)

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See detailInfusion of third-party mesenchymal stream cells after liver transplantation: a phase-1, open-label, clinical study
DETRY, Olivier ULg; VANDERMEULEN, Morgan ULg; DELBOUILLE, Marie-Hélène ULg et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 29

Background: Mesenchymal stromal cells (MSC) are multipotent bone marrow progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed ... [more ▼]

Background: Mesenchymal stromal cells (MSC) are multipotent bone marrow progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. Patients & Methods: Clinical grade MSCs were locally collected from the bone marrow of unrelated healthy donors. They were cultured in a GMP-compliant lab, underwent extensive quality controls and were frozen for storage in a MSC bank. When needed for patient treatment, MSC were thawed and intravenously injected into patients. 10 liver transplant recipients under standard immunosuppression (TAC-MMF-low dose steroids until day 30) received 1.5-3x106/kg MSC on post-operative day 3±2. These patients were prospectively compared to a group of 10 control (MSC-) liver recipients. Primary endpoints were MSC infusion toxicity, and incidence of cancer and opportunistic infections at month 6. Secondary endpoints were patient and graft survivals and rejection at month 6, as well as the effects of MSC on recipients’ immune function and on immunohistology of at month 6 graft biopsies. Results: No MSC infusional toxicity was observed. Both groups were comparable in terms of donor and recipient characteristics. There was no difference in primary end-points between control and MSC groups. No patient developed de novo cancer. There was no statistical difference in patient and graft survivals or in rejection rates. There was no graft rejection in the MSC group. Month-6 graft biopsies were not different according to Banff and fibrosis scores. Discussion: This phase 1 study showed excellent tolerability and safety of a single infusion of third-party MSC after liver transplantation. There were no graft safety issues and no excess of immunosuppression after MSC injection. Further analyses of consequences of MSC injection on the immune profile are needed. The possibility of avoiding calcineurin-inhibitors with repeated MSC injections as main immunosuppressive therapy and/of tolerance induction by MSC infusion should be investigated by further studies. [less ▲]

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See detailX-Linked acro-gigantism (X-LAG) syndrome : a new form of infant-onset pituitary gigantism
Stratakis, CA; Trivellin, G; Rostomyan, Liliya ULg et al

in Abstract book - 14th International Pituitary Congress (2015, March)

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See detailHow snow affects air-sea ice CO2 fluxes ?
Delille, Bruno ULg; Kotovitch, Marie ULg; Van Der Linden, Fanny ULg et al

Poster (2015, March)

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See detailDifferential membrane marker expression in adult rodent bone marrow mesenchymal and neural crest stem cells.
Wislet, Sabine ULg; Coste, Cécile ULg; Neirinckx, Virginie ULg et al

Poster (2015, March)

Bone marrow stem cells are endowed with in vitro multi-lineage differentiation abilities, and constitute an attractive autologous source of material for cell therapy. With regards to recent findings ... [more ▼]

Bone marrow stem cells are endowed with in vitro multi-lineage differentiation abilities, and constitute an attractive autologous source of material for cell therapy. With regards to recent findings, adult mesenchymal stem cells (MSC) are commonly assimilated to neural crest stem cells (NCSC), both isolated from adult bone marrow. The objective of this study was therefore to highlight significant differences for membrane markers between those two cell types. Using the minimal criteria for defining multipotent mesenchymal stromal cells as previously described by The International Society for Cellular Therapy, we were quite surprised that no significant difference could discriminate MSC from NCSC. To define new markers, we first performed a microarray comparison. Based on those results, we validated selected targets by RT-PCR, then by immunocytochemistry. In parallel, we observed that NCSC had the unique property (compared to MSC) to grow as spheres, which could also be used as a purification protocol for NCSC from adult bone marrow. Altogether, we demonstrated that P75NTR was the most significant discriminating marker between MSC and NCSC, isolated from mouse adult bone marrow, which could be used as selecting marker in an enrichment protocol. Sphere formation could then be used as a purification protocol for NCSC. [less ▲]

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See detailELICITOR SCREENING TO PROTECT WINTER WHEAT AGAINST ZYMOSEPTORIA TRITICI BLOTCH
Le Mire, Géraldine ULg; Siah, Ali; Jijakli, Haissam ULg

Poster (2015, March)

Plant protection strategies are strongly focused today on the development of alternative methods in order to complete or replace conventional chemical inputs. Elicitors of biological origin are ... [more ▼]

Plant protection strategies are strongly focused today on the development of alternative methods in order to complete or replace conventional chemical inputs. Elicitors of biological origin are increasingly considered as a promising tool as biocontrol agents. They offer the possibility, through the induction of plant natural defences, to preventively protect plants against a large spectra of diseases. Multiple elicitors have already been identified since their first discovery in the late 70s, but few research has been focused on crop pathogens although such diseases can strongly impact both yield and grain quality. We describe hereby a method of elicitor screening to protect wheat against Zymoseptoria tritici. Focus is made on the importance of a good disease infection protocol in order to achieve screening tests. [less ▲]

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See detailAIP mutations : who should we screen ?
Beckers, Albert ULg

in Abstract book - 14th International Pituitary Congress (2015, March)

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See detailMetabolomic, proteomic and preclinical imaging of patient-derived tumor xenografts for improving treatment of liver metastases patients
Perez Palacios, A; Blomme, A; Boutry, S et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 134

Detailed reference viewed: 30 (10 ULg)
See detailThe role of sea ice in the carbon cycle of Polar Seas: 1D to 3D modelling
Moreau, S.; Vancoppenolle, M.; Delille, Bruno ULg et al

Poster (2015, March)

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See detailCongenital gigantism in a girl with anterior pituitary hyperplasia : a new genes for a new disease
Lysy, PA; Daly, Adrian ULg; Brunelle, C et al

in Abstract book - 43ème Congrès Annuel de la Société Belge de Pédiatrie (2015, March)

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See detailWheat yield sensitivity to climate change across a European transect for a large ensemble of crop models
Pirttioja, N.; Carter, Timothy; Fronzek, S. et al

in Soussana, Jean-Francois (Ed.) Proceedings of the Climate Smart Agriculture 2015 conference (2015, March)

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See detailL'optimisation topologique et la fabrication additive, amélioration de la chaine de conception
Louvigny, Yannick ULg; Nzisabira, Jonathan ULg; Meunier, Bertrand et al

in 14ème colloque national AIP PRIMECA : Produits, Procédés, Systèmes intelligents et durables (2015, March)

L'intérêt de combiner l'optimisation topologique avec les méthodes de fabrication additive vient du fait que d'une part, l'optimisation topologique permet de générer des géométries complexes que les ... [more ▼]

L'intérêt de combiner l'optimisation topologique avec les méthodes de fabrication additive vient du fait que d'une part, l'optimisation topologique permet de générer des géométries complexes que les procédés d'usinage conventionnels ne sont pas capables de réaliser et que, d'autre part, la fabrication additive permet de réaliser des formes complexes telles que des cavités emprisonnées dans un volume ou des canaux non rectilignes, impossibles à reproduire en fonderie ou par usinage. De plus et contrairement aux techniques traditionnelles, la réalisation des géométries complexes n'influence pas le coût pour les techniques additives. Pour ces techniques, le coût est lié principalement au volume de la pièce. La complexité de la pièce n'est plus un problème mais un atout. Toutefois cette combinaison n'est pas encore exploitable au niveau industriel. En effet, les résultats fournis par l'optimisation topologique doivent être modifiés, souvent manuellement, pour les rendre utilisables par les méthodes de fabrication additive. Et ces modifications coûtent cher. Il est donc intéressant de limiter ou au mieux d'éliminer les étapes manuelles de la chaîne de conception. Ce papier propose une chaîne de conception optimisée pour une pièce devant être fabriquée par les méthodes additives. En outre, la prise en compte des contraintes inhérentes aux procédés de fabrication par addition de matière reste problématique. Une démarche simplifiée est proposée pour identifier les types de contraintes inhérentes aux procédés de fabrication par addition de matière, les quantifier pour certaines techniques et les intégrer dans le code d'optimisation topologique. La nouvelle chaine de conception minimise les interventions du concepteur qui rendent le processus plus lourd et moins viable industriellement. Dans cette nouvelle chaîne de conception, certaines étapes sont réalisées plus rapidement et génèrent de meilleurs résultats. [less ▲]

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See detailNew approach of calculation of dynamics of ball bearings
Bozet, Jean-Luc ULg; Servais, Christophe ULg

Conference (2015, March)

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See detailA comparison of grey-box and black-box approaches in nonlinear state-space modelling and identification
Noël, Jean-Philippe ULg; Schoukens, Johan; Kerschen, Gaëtan ULg

Conference (2015, March)

In the present contribution, it is shown that, in the case of mechanical systems where nonlinearities are physically localised, the general structure of black-box nonlinear state-space models can be ... [more ▼]

In the present contribution, it is shown that, in the case of mechanical systems where nonlinearities are physically localised, the general structure of black-box nonlinear state-space models can be drastically simplified. A more parsimonious, grey-box state-space representation is derived, which is found to be compatible with Newton's second law of dynamics. For demonstration purposes, black-box and grey-box state-space models of the Silverbox benchmark, i.e. an electrical mimicry of a single-degree-of-freedom mechanical system with cubic nonlinearity, are identified using a maximum likelihood estimator. It is found that the grey-box approach allows to reduce markedly modelling errors with respect to a black-box model with a comparable number of parameters. It is also suggested that the greater accuracy of the grey-box model lends itself to the computation of reliable confidence bounds on the model parameters. [less ▲]

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See detailMultitasking abilities in persons diagnosed with schizophrenia: a new tool and cognitive model.
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Laroi, Frank ULg

in Schizophrenia Bulletin (2015, March), 41(Supplement 1),

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities (Semkovska et al., 2010). Multitasking refers to ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities (Semkovska et al., 2010). Multitasking refers to activities (e.g. preparing a meal) where the person has to: (a) carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; (b) define the tasks’ targets; (c) and where the person is faced with unexpected problems during the realization of these tasks (Burgess, 2000). However, the cognitive underpinnings of multitasking abilities have never been adequately explored in schizophrenia. Further, only two cognitive models exist in the literature, which are based on student (Logie et al., 2011) and neurological (Burgess et al., 2000) samples. Both of these models suggest three primary constructs: Memory, Planning and Intent. There are, however, several limitations related to the way multitasking abilities were evaluated in these studies. We thus developed a computerized real-life activity task - the Computerized Meeting Preparation Task (CPMT), which was specifically designed to take into account the multitasking nature of certain everyday life activities. Using this task, and based on previous studies (Burgess et al., 2000; Logie et al., 2011), the aim of the present study was to evaluate multitasking abilities in schizophrenia and to do so in a new cognitive model of multitasking that takes into account certain cognitive functions that are not integrated in existing models. Methods: Fifty-seven individuals with schizophrenia and 41 matched healthy controls completed the CMPT. Participants were also evaluated with a battery of cognitive tests. Results: The results suggest that the CMPT possesses good sensitivity and confirmed the three underlying constructs of multitasking (Memory, Planning and Intent), which were found to be underpinned by several cognitive functions and multitasking aspects. Conclusion: Taken together, this new cognitive model and the CMPT could be a good basis for cognitive interventions of multitasking abilities in schizophrenia. Burgess, P.W., 2000. Strategy application disorder: the role of the frontal lobes in human multitasking. Psychol Res 63, 279-288. Logie, R., et al., 2011. Multitasking: multiple, domain-specific cognitive functions in a virtual environment. Mem Cogn 39, 1561-1574. Semkovska, M. et al., 2004. Assessment of executive dysfunction during activities of daily living in schizophrenia. Schizophr Res 69, 289-300. [less ▲]

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See detailHydro-mechanical simulation in a deep excavation in Boom Clay
Hong, P.Y.; Cui, Y.J.; Pereira, J.M. et al

Poster (2015, March)

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See detailBlue sky and green bugs – How physical parameters and algal speciation influence DMSP and DMS profiles in Antarctic winter sea ice
Uhlig, C.; Rintala, J.-M.; Tison, J.-L. et al

Poster (2015, March)

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See detailIntroduction aux travaux et conclusions
Miesse, Hélène ULg; Geremicca, Antonio ULg

Conference (2015, March)

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See detailEtude GEROX : Evaluation du statut de stress oxydant
CHRISTELBACH, SOPHIE; RICOUR, Céline ULg; Dardenne, Nadia ULg et al

Poster (2015, March)

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See detailCharacteriation of GPR101 expression across different species
Trivellin, G; Bjelobaba, I; Daly, Adrian ULg et al

in Abstract book - ENDO 2015 (2015, March)

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See detailPreliminary analysis of Martian dayglow observed by the Imaging Ultraviolet Spectrograph onboard MAVEN
Jain, Sonal; Stewart, Ian; Schneider, Nick et al

Conference (2015, March)

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See detailPreliminary analysis of Martian nightglow and aurora observed by MAVEN's Imaging UltraViolet Spectrograph
Stiepen, Arnaud ULg; Stewart; Jain et al

Conference (2015, March)

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See detailImpact of intensive enteral nutrition in association with corticosteroïds in the treatment of severe alcoholic hepatitis: a multicenter randomized controlled trial
Moreno, C; Trepo, E; Louvet, A et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 01

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See detailLes fonctions de la procédure en droit de la concurrence
Petit, Nicolas ULg; Neyrinck, Norman ULg

Conference (2015, March)

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See detailEffects of transcranial magnetic stimulation coil orientation and pulse width on short-latency afferent inhibition
Hannah, Ricci; D'Ostilio, Kevin ULg; Goetz, Stefan et al

Poster (2015, March)

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See detailTowards a yeast reference interactome
Desbuleux, Alice ULg

Poster (2015, March)

Despite an increasing number of interactomic datasets already available for model organisms and humans, many aspects remain contradictory, debatable or unclear due to the lack of complete high-quality ... [more ▼]

Despite an increasing number of interactomic datasets already available for model organisms and humans, many aspects remain contradictory, debatable or unclear due to the lack of complete high-quality networks. It has, for instance, been proposed that macromolecule connectivity in interactome maps reflects functional importance, functional relatedness, pleiotropy, implication in diseases, and other important biological characteristics. The most notorious example of such relationships concerns so-called essential genes believed to correspond to highly connected hubs that are critical to network integrity. Such claims have led to debate in the literature because connectivity could also be explained by bias and uneven coverage of the interactome space. To provide fresh insight into these questions, we produced a new, systematic interactome map for S. cerevisiae, organism for which a plethora of systematic interactomic and functional data is available. This alternative view of the interactome network was generated by modifying our screening pipeline based on our empirically-controlled framework. Using a new high-quality ORFeome collection and a new assay version, we systematically performed three replicate yeast-two hybrid screens. This produced a map of 1,200 protein-protein interactions, which, while of similar size as previously published interactome maps, covers the entire proteome without bias. These interactions were subsequently successfully validated using an orthogonal protein complementation assay based on a split Gaussia princeps luciferase. The latest analyses of this new map and progress towards generating a first Yeast Reference Interactome map will be presented. [less ▲]

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See detailExpel: a novel non-destructive method for mining soluble tumor biomarkers
Costanza, B; Blomme, A; MUTIJIMA NZARAMBA, Eugène ULg et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 13

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See detailEvaluation de l’efficacité de la simulation haute fidélité dans la prise en charge des troubles du rythme cardiaque chez l’enfant: étude pilote
SCHUMACHER, Katharina ULg; Seghaye, Marie-Christine ULg; Baugnon, Thomas et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1),

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See detailNumerical crashworthiness analysis of an offshore wind turbine monopile impacted by a ship
Bela, Andreea ULg; Le Sourne, Hervé; Buldgen, Loïc ULg et al

in Shenoi, R Ajit; Soares, Carlos Guedes (Eds.) Analysis and Design of Marine Structures (2015, March)

The consequences of collision events can range from minor structural damages of the supporting structure to complete collapse of the wind turbine, which may lead to disruptions of the electricity ... [more ▼]

The consequences of collision events can range from minor structural damages of the supporting structure to complete collapse of the wind turbine, which may lead to disruptions of the electricity production and, at worst, to sinking of the striking ship with probability of loss of human lives or/and pollution. For all these reasons, a collision risk analysis becomes mandatory at the pre-design stage in order to identify the collision scenarios having the greatest probabilities of occurrence, to estimate the consequences of collision events and to ensure safe operations through the wind farm service life. The goal of this paper is to outline the behavior of the monopile foundations during ship collision by performing non-linear finite element simulations. Many collision scenarios are analyzed in order to study the sensitivity of the monopile to various parameters like impact striking ship velocity, nacelle mass, wind direction, soil stiffness, vertical location of the impact point, wind orientation … The internal energy dissipated by deformation of the monopile, the crushing force and the indentation of the crushed area are compared for different situations, as well as the overall displacements of the supporting structure. [less ▲]

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See detailCan the exploration of left space be induced implicitly in unilateral neglect?
Wansard, Murielle ULg; Bartolomeo, Paolo; Vanderaspoilden, Valérie et al

Poster (2015, March)

The purpose of the present study was to explore the ability of neglect patients to detect and exploit the predictive value of a cue to respond more quickly and accurately to targets on their ... [more ▼]

The purpose of the present study was to explore the ability of neglect patients to detect and exploit the predictive value of a cue to respond more quickly and accurately to targets on their contralesional side in a Posner spatial cueing task. The majority of the cues (i.e. 80%) were invalid, indicating that the target would appear on the opposite side, although patients were not informed of this bias. Our results demonstrate that some neglect patients were able to extract the cue’s predictability and use it to orient faster toward the left. This cueing effect was present even in patients who were subsequently unable to describe the predictive character of the cues, and thus was not modulated by reportable awareness of the cue-target relation. [less ▲]

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See detailControl of plankton phenology by climate variation in a Mediterranean coastal area : results from a long-term study (1979-2011)
Goffart, Anne ULg; Collignon, Amandine ULg; Hecq, Jean-Henri ULg

Conference (2015, March)

Physical processes are known to play major roles in marine plankton succession. However, few studies have addressed the mechanisms that regulate phyto- and zooplankton phenology in a context of changing ... [more ▼]

Physical processes are known to play major roles in marine plankton succession. However, few studies have addressed the mechanisms that regulate phyto- and zooplankton phenology in a context of changing climate. Here we used a unique long-term (1979-2011) time series performed in a Mediterranean coastal area unbiased by local anthropogenic pressure (PHYTOCLY station, Bay of Calvi, Corsica) to understand how environmental forcing affects the timing, duration and magnitude of the winter-spring phyto- and zooplankton blooms. We showed that phyto- and zooplankton blooms were bottom-up controlled by the establishment of favourable abiotic conditions, i.e. nutrient replenishment by vertical mixing under specific water temperature and wind conditions, for which thresholds were defined. According to the intensity of winter characteristics, there were strong differences in both the abundance and composition of phyto- and zooplankton during the winter-spring period. Our study is consistent with the recent reports that, when occurring, diatoms peaks were added to the initial phytoplankton groups instead of replacing them. In contrast, zooplankton groups followed a replacement sequence. Based on the results provided by our time series, we show that plankton phenology in the Bay of Calvi is highly controlled by climate variation and exhibits contrasted patterns in response to different scenarios of environmental forcing. [less ▲]

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See detailOptimisation of the Nitrogen fertilisation in the context of climate change
Dumont, Benjamin ULg; Basso, Bruno; Bodson, Bernard ULg et al

in Soussana, Jean-Francois (Ed.) Proceedings of the Climate Smart Agriculture 2015 conference (2015, March)

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See detailMulticenter Belgian experience of sofosbuvir (medical need program) in very difficult-to-treat HCV patients: safety and efficacy results.
Degre, D; Laleman, W; Verhelst, X et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 03

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See detailDisease characteristics of patients with X-linked acrogigantism (X-LAG) syndrome
Daly, Adrian ULg; Lodish, MB; Trivellin, G et al

in Abstract book - ENDO 2015 (2015, March)

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See detailInfluences of blubber composition and profile in the assessment of POPs levels in free-ranging cetaceans
Pinzone, Marianna ULg; Budzinski, Hélène; Tasciotti, Aurelie et al

Poster (2015, February 28)

Investigating the food and feeding ecology of free-ranging cetaceans has always been very challenging. Still now, mass stranding events represent almost the only opportunity to collect valid information ... [more ▼]

Investigating the food and feeding ecology of free-ranging cetaceans has always been very challenging. Still now, mass stranding events represent almost the only opportunity to collect valid information on these large and elusive animals. Biopsy darting is a non-lethal tissue sampling technique which permits the collection of tissues from living and healthy individuals. However, important discussions exist about how efficient this method is in chemical analyses where the percentage lipid content of the tissue is of great importance. Biopsies of skin and blubber were conducted on 49 long-finned pilot whales (Globicephala melas), 61 sperm whales (Physeter macrocephalus) and 70 fin whales (Balaenoptera physalus) in the North Western Mediterranean Sea (NWMS) from 2006 to 2013. Lipid content, δ13C, δ15N values and ΣPCBs were analysed and compared with previous studies conducted on stranded and biopsied individuals. Lipids extraction was operated via ASE; δ13C, δ15N values and POPs levels were assessed through IR-MS and GC-MS respectively. δ15N values were 12.2±1.3‰ for sperm whales, 10.5±0.7‰ for pilot whales and 7.7±0.8‰ in fin whales, positioning sperm whales at higher trophic levels. δ13C instead was similar and amounted to −17.3±0.4‰, −17.8±0.3‰ and −18.7±0.4‰ respectively. Pilot whales presented the highest concentrations of ΣPCBs (38666 ± 25731ng.g-1 lw) followed by sperm whales (22849 ± 15566ng.g-1 lw) and fin whales (5721±5180ng.g-1 lw). Lipids percentage differed significantly between species. Sperm whales showed the lowest lipid content with an average of 12±9%, whereas for long-finned pilot whales it was 22±21% and for fin whales 31±14%. Lipid content of the two odontocetes varied between years of sampling, whilst for fin whales remained similar. The PCBs concentrations, especially in sperm whales, were in discordance with previous studies conducted in the same area and our δ13C, δ15N values. We hypothesized that (1) the extreme low lipid content found in the blubber, (2) the extraction procedure and (3) the biopsies technique, could explain such different pattern. Several papers demonstrated how POPs concentrations in cetaceans blubber are strongly influenced by its thickness, stratification and lipid profile. Therefore, the particular characteristics of blubber composition of deep—diving income breeders such as sperm whales, may not allow an efficient representation of POPs concentrations through the use of biopsies. [less ▲]

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See detailNœuds de Savoie et cordelières de Louise de Savoie
Fagnart, Laure ULg

Conference (2015, February 27)

Comtesse puis duchesse d’Angoulême, Louise de Savoie (1476-1531) est l’une des personnalités les plus influentes de la première Modernité européenne. Elle n’est pas seulement la mère de deux enfants ... [more ▼]

Comtesse puis duchesse d’Angoulême, Louise de Savoie (1476-1531) est l’une des personnalités les plus influentes de la première Modernité européenne. Elle n’est pas seulement la mère de deux enfants illustres, Marguerite, future reine de Navarre, et François, futur François Ier, elle est aussi la sœur de Philibert II le Beau, duc de Savoie. Une fois son fils monté sur le trône de France, Louise domine le Conseil et assure, à deux reprises, la régence du royaume. Son action concerne encore les arts et les lettres : amatrice d’objets d’art et bibliophile avertie, elle demande à Léonard de Vinci d’imaginer une ville et un palais neuf à Romorantin, participant de la sorte à la diffusion en France des idées et des formes venues d’Italie. Curieusement, alors que son influence fut considérable, Louise de Savoie n’a pas fait l’objet d’une monographie récente (un ouvrage collectif à son propos paraîtra toutefois en 2015). Son emblématique n’a plus été analysé depuis les travaux d’Anne-Marie Lecocq (1987), qui s’était essentiellement concentrée sur les signes présents dans les livres qu’elle commanda pour soutenir l’éducation de ses enfants. À l’occasion de cette communication – prolongeant ainsi une recherche entreprise avec Pierre-Gilles Girault – nous voudrions revenir sur le discours héraldique de Louise de Savoie, en explicitant l’une de ses devises favorites, la cordelière. Pour la mère de François Ier, la corde à plusieurs nœuds revêt plusieurs significations. D’abord, puisqu’elle se compose de nœuds de Savoie, un emblème largement diffusé au début du XVIe siècle, notamment sous l’influence de Philibert II le Beau et Marguerite d’Autriche, elle souligne l’appartenance de la dame à la maison de Savoie. Ensuite, et ce de façon inédite au sein de la maison de Savoie, la cordelière de Louise associe nœuds de Savoie et cordon franciscain, une référence que nous proposons d’expliquer non pas uniquement, comme on le fait traditionnellement, par les liens prétenduement étroits qui reliaient la mère de François Ier avec l’ordre des Franciscains. Pour Louise, il s’agit sans doute aussi de se situer dans la lignée d’Anne de Bretagne, à laquelle la cordelière est indéniablement liée. [less ▲]

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See detailPACITA "User" Summer Schools in Liège 2012 and Cork 2014
Rosskamp, Benedikt ULg; Fitzgerald, Ciara

Conference (2015, February 27)

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See detail"Mimer le savoir pour mieux le miner : le guide pratique selon Pierre La Police"
Belloi, Livio ULg

Conference (2015, February 27)

En s'appuyant sur "Nos meilleurs amis et l'acte interdit" (Cornelius, 2011, 4e édition), la présente communication examine le traitement parodique que le dessinateur français Pierre La Police réserve au ... [more ▼]

En s'appuyant sur "Nos meilleurs amis et l'acte interdit" (Cornelius, 2011, 4e édition), la présente communication examine le traitement parodique que le dessinateur français Pierre La Police réserve au discours à caractère encyclopédique ou didactique. Dans son rapport distancié et facétieux au savoir, Pierre La Police creuse le sillon ouvert par Gustave Flaubert et son fameux "Dictionnaire des idées reçues". [less ▲]

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See detailGian Matteo Giberti et les lettres à travers la correspondance de jeunesse
Valenti, Gianluca ULg

Conference (2015, February 27)

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See detailComparison of early stages of colorectal cancer by label free proteomics
QUESADA CALVO, Florence ULg; MEUWIS, Marie-Alice ULg; Bertrand, Virginie ULg et al

in Acta Gastroenterologica (2015, February 27)

Introduction and objectives: Colorectal cancer (CRC) is the second most frequent cancer in women and the third in men. Identification of the mechanisms of progression in these early CRC stages is ... [more ▼]

Introduction and objectives: Colorectal cancer (CRC) is the second most frequent cancer in women and the third in men. Identification of the mechanisms of progression in these early CRC stages is important to develop new diagnostic and therapeutic tools. Formalin-Fixed Paraffin-Embedded (FFPE) specimens are materials that enable proteomic clinical research. Hence our aim was to address the comparison of FFPE samples from early CRC stages patients using shotgun proteomic analysis. Methods: We performed a retrospective study on 36 CRC tissue samples (pT1N0M0, n=16 and pT2N0M0, n=20) compared together and with 40 control tissue samples (20 patients with diverticulitis, using paired inflamed (DI) and healthy tissue (DH)). Each tissue slice was macrodissected to enrich in epithelial cells. We used FFPE-FASP kit (Expedeon) for sample preparation and protein digests were analyzed using 2D-nanoAquity UPLC separation online with Q-Tof Synapt HDMSTM G2 using ion mobility as additional separation. We performed protein identification and differential analysis using Progenesis QI for proteomics (Nonlinear Dynamics). Results and discussion: We selected 149 proteins differentially distributed between T1 and T2 CRC stages which were not significantly different between CRC and DH or DI. Only 30 proteins were significantly more abundant in T1 versus T2 and 119 were distributed inversely, with a minimum fold ratio of 2. Among those, ATP synthase subunit beta, Aspartate-tRNA ligase, Haptoglobin and Kininogen were identified. . Moreover, we validated Kininogen and 3 others proteins with a significant differential distribution between pT1N0M0 and pT2N0M0 stages by immunohistochemistry. Conclusion: This FFPE retrospective study comparing T1 and T2 CRC highlighted proteins already previously identified as potential CRC biomarkers. These proteins may reflect important early changes in cancer development and may help understanding early tumor progression. [less ▲]

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See detailWho’s the gatekeeper? Ensuring and Legitimating a Participatory Decision-Making Process in the context of Nuclear Waste Management
Parotte, Céline ULg

Conference (2015, February 27)

In Belgium, Nuclear Waste Management (NWM) is conducted by a Federal Agency called ONDRAF - i.e. the “National Agency for Radioactive Waste and Enriched Fissile Materials”. Adhering to a largely accepted ... [more ▼]

In Belgium, Nuclear Waste Management (NWM) is conducted by a Federal Agency called ONDRAF - i.e. the “National Agency for Radioactive Waste and Enriched Fissile Materials”. Adhering to a largely accepted vision, NWM is considered by ONDRAF as a long-term and complex issue, consisting in technical, social, economic and ethical questions. In this respect, scientific literature invites to clarify and address those aspects in a decision-making process that could benefit from meaningful public participation (Callon, Lascoumes, and Barthes 2001). In this context, many stakeholders (e.g. citizens, researchers, industrialists, civil society organizations, the European Union... and ONDRAF itself) are in demand of a “conductor” that can organize, ensure and legitimize such a participatory decision-making process. Many questions emerge from this demand. Who can be the gatekeeper of this process? What could be his role? For which purposes? In addition to that, how should participation be organized/assessed/controlled? To that regard, the purpose of this paper is twofold. First, I elaborate a possible definition of “gatekeeping a participatory decision-making process concerning NWM in Belgium”. Second, I question the possible role of Technology Assessment (TA) - as an institution as well as a set of approached - in this context. To address those questions, I rely on a combination of theoretical and empirical materials – i.e. semi directive interviews with policy makers and members of Belgian and French agencies in charge of NWM. [less ▲]

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See detailPotential Proteomic Biomarkers Associated with Mucosal Healing and Relapse Prediction after IFX Withdrawals in Crohn’s Disease
MEUWIS, Marie-Alice ULg; QUESADA CALVO, Florence ULg; Baiwir, Dominique ULg et al

in Acta gastroenterologica (2015, February 26)

Introduction and objectives: In Crohn's disease (CD), there is a discrepancy between clinical activity of the disease (symptoms) and intestinal healing. However absence of tissue healing is associated ... [more ▼]

Introduction and objectives: In Crohn's disease (CD), there is a discrepancy between clinical activity of the disease (symptoms) and intestinal healing. However absence of tissue healing is associated with the risk of relapse and tissue damage progression. Endoscopy is costly and invasive. Hence biomarkers correlating with intestinal healing could improve disease management and potentially decrease the number of endoscopy when patients are in clinical remission. Aim: We aimed to identify potential biomarkers associated to CD mucosal healing and relapse after IFX withdrawals by a shotgun label-free proteomic study. Methods: We used the STORI1 clinical trial cohort (n=103) aiming at identifying markers associated to relapse prediction after Infliximab treatment withdrawals. We used serum samples of patients in clinical remission (at base line). We grouped these according to the degree of intestinal healing seen at endoscopy or according to relapse occurrence during the 28 month follow-up and composed pooled samples. We performed depletion of the 20 most abundant plasma proteins on each serum pools and ran a proteomic label-free differential analysis using 2D-nanoUPLC-MSE HDMS Synapt G2 for data acquisition. We performed different statistical analysis. Moreover, a Gene Ontology annotation was also performed for the potential biomarkers highlighted. Results and Discussion: We identified analysing these depleted serum pools 430 different proteins and 188 proteins common to all samples. Among these, 40 were found with a significant differential abundance in the groups compared. We selected some among the most significant one (ratio>1.3) or being by nature consistent with the context of this study (sample origin and clinical question addressed). For example, the C-reactive protein (CRP) was found with a significant Ratio of 2 between Relapsers and Non Relapsers. The other potential biomarkers associated to mucosal healing or to relapse prediction, were selected for further validation by Western Blot analysis (WB), routine laboratory tests and also by a Mass Spectrometry based technology: multiplexed selected reaction monitoring (SRM). Multiplexed SRM will enable quantitative analysis of these candidates in each individual patient as well as WB tests. Conclusions: This research strategy and the validation results on potential biomarkers associated to mucosal healing or relapse after treatment cessation in this cohort of CD patients, as well as tests done on other CD patients, might provide new opportunities for patient follow-up test developments. The next step is to perform SRM validation on the STORI cohort and design signatures using these potential biomarkers SRM data for prognosis power evaluation. 1. Louis E, Mary JY, Vernier-Massouille G, et al. Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped. Gastroenterology 2012;142:63-70 e5; quiz e31. [less ▲]

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See detailTeaching and Training TA
Delvenne, Pierre ULg; Rosskamp, Benedikt ULg; Bütschi, Danielle et al

Poster (2015, February 26)

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See detailLes peptides natriurétiques: le point de vue du biologiste
LE GOFF, Caroline ULg

Conference (2015, February 26)

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See detailLes peptides natriurétiques: le point de vue du biologiste
LE GOFF, Caroline ULg

Conference (2015, February 26)

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See detail6. Lutte intégrée contre les maladies
Bataille, Charlotte; Duvivier, Maxime; Eylenbosch, Damien ULg et al

in Watillon, Bernard; Bodson, Bernard (Eds.) Livre Blanc Céréales (2015, February 25)

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See detail10. Perspectives - 2. Utilisation de l'imagerie hyperspectrale proche infrarouge pour estimer la biomasse racinaire d'une culture de froment
Eylenbosch, Damien ULg; Fernandez Pierna, Juan Antonio; Baeten, Vincent et al

in Watillon, Bernard; Bodson, Bernard (Eds.) Livre Blanc Céréales (2015, February 25)

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See detailTechnology Assessment in East Asia: Experiences and New Approaches
Moniz, Antonio; Yoshizawa, Go; Van Oudheusden, Michiel ULg

Conference (2015, February 25)

Integrating social and ethical concerns in innovation practice is a well-documented and debated issue in the United States and in Europe (namely through the EU-wide PACITA project). Related developments ... [more ▼]

Integrating social and ethical concerns in innovation practice is a well-documented and debated issue in the United States and in Europe (namely through the EU-wide PACITA project). Related developments in other parts of the world are less discernible – at least to Westerns. Yet, as witnessed by the emergence of technology assessment (TA) in countries like Japan, TA and TA-like activities have a unique and long history and continue to play a role in contemporary STI processes (e.g. in the area of citizen engagement with nanotechnologies, or energy policy). Taking these observations as its entry point, this panel asks how STI governance is locally enacted in Asian knowledge-driven economies. Like their Western counterparts, nations like China, Indonesia, Japan, the Republic of Korea, Singapore, Taiwan, etc., have undergone, and continue to undergo, rapid science- and technology-driven industrialization. In these processes, TA and TA-like activities develop with STI policies and programs and typically do so in nation- and region-specific ways. To render these processes, policies, and programs visible, and understand their implications for STI governance, this panel will discuss contributions that: • Describe and conceptualize how TA and TA-like activities have emerged in Asian KBEs, and in what particular forms (e.g. academic and parliamentary TA programs, linked to certain technologies and/or actors, which methods are used and why, etc.). • Reflect how these activities has evolved with, sustained, and/or countered, STI policies on the regional, national, and international level. • Compare and contrast how TA is, or is not, institutionalized in Asian countries and regions, e.g. through initiatives to initiate or abolish various TA forms, such as health TA, early-warning TA, and parliamentary TA; and/or point to prospects for TA capacity building. • Situate the above processes within a broader theory of, and movement towards, new STI governance frameworks, such as anticipatory governance, responsible innovation, public engagement, and/or others. By placing the development in historical, sociological, and comparative perspective, the panel seeks to open a space for critical reflection on the potential, problems, and limitations of initiating TA in Asia and draw connections to STI governance processes in other KBEs across the globe. [less ▲]

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See detailPropagation of uncertainties using probabilistic multi-scale models
Lucas, Vincent ULg; Wu, Ling ULg; Paquay, Stéphane et al

Conference (2015, February 25)

When applying a multiscale approach, the material behavior at the macro-scale can be obtained from an homogenization scheme. To this end, at each integration-point of the macro-structure, the macrostress ... [more ▼]

When applying a multiscale approach, the material behavior at the macro-scale can be obtained from an homogenization scheme. To this end, at each integration-point of the macro-structure, the macrostress tensor is related to the macro-strain tensor through the resolution of a micro-scale boundary value problem. At the micro-level, the macro-point is viewed as the center of a Representative Volume Element (RVE). However, to be representative, the micro-volume-element should have a size much bigger than the micro-structure size. When considering structures of reduced sizes, such as micro-electro-mechanical systems (MEMS), as the size of the devices is only one or two orders of magnitude higher than the size of their microstructure, i.e. their grain size, the structural properties exhibit a scatter at the macro-scale. The representativity of the micro-scale volume element is lost and Statistical Volume Elements (SVE) should be considered in order to account for the micro-structural uncertainties. These uncertainties should then be propagated to the macro-scale in order to predict the device properties in a probabilistic way. In this work we propose a non-deterministic multi-scale approach [1] for poly-silicon MEMS resonators. A set of SVEs is first generated under the form of Voronoi tessellations with a random orientation assigned for each silicon grain of each SVE. The resolution of each micro-scale boundary problem is performed by recourse to the computational homogenization framework, e.g. [2], leading to meso-scale material properties under the form of a linear material tensor for each SVE. Applying a Monte-Carlo procedure allows a distribution of this material tensor to be determined at the meso-scale. The correlation between the meso-scale material tensors of two SVEs separated by a given distance can also be evaluated. A generator of the meso-scale material tensor is then implemented using the spectral method [3]. The generator [1] accounts for a lower bound [4] of the meso-scale material tensor in order to ensure the existence of the second-order moment of the Frobenius norm of the tensor inverse [5]. A macro-scale finite element model of the beam resonator can now be achieved using regular finite-element, i.e. not conforming with the grains, and the material tensor at each Gauss point is obtained using the meso-scale generator, which accounts for the spatial correlation. A Monte-Carlo method is then used at the macro-scale to predict the probabilistic behavior of the MEMS resonator. As an example the beam resonator illustrated in Fig. 1(a) is made of poly-silicon, and each grain has a random orientation. Solving the problem with a full direct numerical simulation combined to a Monte-Carlo method allows the probability density function to be computed as illustrated in Fig. 1(b). However this methodology is computationally expensive due to the number of degrees of freedom required to study one sample. The proposed non-deterministic multi-scale strategy allows reducing this computational cost as the Monte-Carlo processes are applied on much smaller finite-element models. The method can also be applied in the context of fracture of thin poly-silicon film [6]. In this case, a set of meso-scopic cohesive laws can be obtained at the meso-scale from the resolution of different SVEs. The meso-scopic cohesive laws are obtained for each RVE from the finite element resolution of the Voronoi tessellations using the method proposed in [7]. The resulting statistical values for the critical energy release rate and for the critical strength can then be used for macro-scale simulations. [less ▲]

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See detail4. La fumure azotée
Meza Morales, Walter ULg; Monfort, Bruno; Dumont, Benjamin ULg et al

in Watillon, Bernard; Bodson, Bernard (Eds.) Livre Blanc Céréales (2015, February 25)

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See detail10. Perspectives - 1. La Lutte contre les pucerons grâce aux odeurs: développement d'une formulation phéromonale
Fassotte, Bérénice ULg; Vandereycken, Axel ULg; Chevalier Mendes Lopes, Thomas ULg et al

in Watillon, Bernard; Bodson, Bernard (Eds.) Livre Blanc Céréales (2015, February 25)

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See detail2. Implantation des cultures
Eylenbosch, Damien ULg; Meza Morales, Walter ULg; Monfort, Bruno et al

in Watillon, Bernard; Bodson, Bernard (Eds.) Livre Blanc Céréales (2015, February 25)

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See detailThe AgMIP Soil and Crop Rotation Initiative
Basso, Bruno; Dumont, Benjamin ULg; Shcherbak, Iurii et al

Conference (2015, February 25)

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