References of "Scientific congresses and symposiums"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 1101 to 1200 of 42400     7 8 9 10 11 12 13 14 15 16 17     Comparison of bacteriological and genetic identification of mammary pathogens in milk samples from cows with chronic mastitis in Wallonia (Belgium)Ngassam Tchamba, Cyrille ; Rao, Anne-Sophie ; Duprez, Jean-Noël et alPoster (2015, June)Detailed reference viewed: 18 (5 ULg) Historical evolution of fish biodiversity and capture periodicity in the River Meuse (Belgium) as revealed by 15 consecutive years of fishpass monitoringBenitez, Jean-Philippe ; Dierckx, Arnaud ; Nzau Matondo, Billy et alConference (2015, June)In the River Meuse at 323km upstream from the North Sea, the hydroelectric dam of Lixhe (rated power of 5300KW) is equipped with two fishpasses: one pool and weir fishpass (in operation since 1980; 0.13m³ ... [more ▼]In the River Meuse at 323km upstream from the North Sea, the hydroelectric dam of Lixhe (rated power of 5300KW) is equipped with two fishpasses: one pool and weir fishpass (in operation since 1980; 0.13m³.s-1 operating flow) and one vertical slot fishpass (in operation since 1998; 1m3.s-1 operating flow). Both fishpasses were scientifically monitored using capture traps during 15 consecutive years (from 1999 to 2014). The objective of the study is to analyse i) the evolution of fish stock and biodiversity over 15 years and ii) the capture periodicity of fish and it’s variation over years. During the considered period, we observed 36 species at adult stage (88597 individuals with 75% of cyprinids) and 13 species at juvenile (0+) stage (335067 individuals with 90% of cyprinids). Global results between 1999 and 2014 showed a drastic reduction in capture per year (>90%) for some species like Anguilla Anguilla, Alburnus alburnus, Blicca bjoerkna, Rutilus rutilus and Tinca tinca. Whereas other species have emerged like Aspius aspius and Silurus glanis. For the 0+, an important interannual variation is observed from few individuals to several tens of thousands per year. The comparison between both fishpasses indicated a greater use (>50%) of the vertical slot fishpass by rheophilic species and species that have good swimming ability. The analysis of capture periodicity for the most abundant species at adult stage demonstrated the presence of stable behaviours between years for the Abramis abrama and B. bjoerkna respectively a Q50 of the capture day of the year from 108th to 144th day at mean=17°C and from 118th to 155th day at mean=18°C. In contrast other species have patterns more variables (Barbus barbus: Q50 from 96th to 266th day; R. rutilus: from 10th and 309th day). Finally the 0+ exhibited a capture periodicity stable in time during the summer. [less ▲]Detailed reference viewed: 35 (3 ULg) How do synthetic rhamnolipids interact with biomimetic systems of plant plasma membranes ? Key role of the chemical structures."Nasir, Mehmet Nail ; Lins, Laurence ; Fauconnier, Marie-Laure et alPoster (2015, June)Detailed reference viewed: 32 (3 ULg) “Elements of the Sublime (and the Grotesque) in Crime Fiction”Dechene, Antoine Conference (2015, June)Detailed reference viewed: 16 (1 ULg) Traitement psycho-judiciaire des mineurs auteurs de faits qualifiés infraction à caractère sexuel : quels critères décisionnels ?Glowacz, Fabienne ; Camarda, SabrinaPoster (2015, June)Detailed reference viewed: 23 (0 ULg) Do T2-hypointense GH-secreting pituitary adenomas behave differently under somatostatin analogues as primary therapy in acromegaly ?Potorac, Iulia ; PETROSSIANS, Patrick ; Daly, Adrian et alin The International Journal of The Romania Society of Endocrinology - Abstract book (2015, June)Detailed reference viewed: 18 (1 ULg) Les leviers de l'inovation pédagogique: contraintes externes vs régulations internesScheffers, Patricia in Scheffers, Patricia (Ed.) Actes du colloque (2015, June)Depuis les années 60, la fréquence de mutations organisationnelles de l'enseignement supérieur et universitaire en Belgique s'amplifie et adopte même un rythme frénétique ces dix dernières années. Les ... [more ▼]Depuis les années 60, la fréquence de mutations organisationnelles de l'enseignement supérieur et universitaire en Belgique s'amplifie et adopte même un rythme frénétique ces dix dernières années. Les causes sont tour à tour l'évolution des professions et la volonté politique et/ou économique de restructuration. Deux niveaux de régulations pédagogiques sont amenés à s'articuler. D'une part, celui de l'enseignant acteur-réflexif de son enseignement et d'autre part, des injonctions externes qui réorganise le cadre général. Retour d'expérience sur les innovations en Faculté d'Architecture à Liège. [less ▲]Detailed reference viewed: 41 (10 ULg) Dynamic modeling of thermal systems using a semi-empirical approach and the ThermoCycle Modelica LibraryAltés Buch, Queralt ; Dickes, Rémi ; Desideri, Adriano et alin Proceedings of the 28th International Conference on Efficiency, Costs, Optimization and Simulation of Energy Systems (2015, June)This paper proposes an innovative approach for the dynamic modeling of heat exchangers without phase transitions. The proposed thermo-flow model is an alternative to the traditional 1D finite-volumes ... [more ▼]This paper proposes an innovative approach for the dynamic modeling of heat exchangers without phase transitions. The proposed thermo-flow model is an alternative to the traditional 1D finite-volumes approach and relies on a lumped thermal mass approach to model transient responses. The heat transfer is modeled by the well-known Logarithmic Mean Temperature Difference approach, which is modified to ensure robustness during all possible transient conditions. The lumped parameter models are validated with references models and tested within a Concentrating Solar Power plant model. Results indicate that the developed lumped models are robust and computationally efficient, ensuring the convergence of the Newton Solver. They are significantly faster (~10-fold) than the traditional finite volume models, although a more extensive comparisons would be needed to confirm this figure. They are well suited to be integrated in larger system models, but are not appropriate for the simulation of detailed thermo-flow phenomena. [less ▲]Detailed reference viewed: 48 (7 ULg) Neuronal excitation/inhibition balance is set by the need for sleep and the biological clockPhillips, Christophe ; Chellappa, Sarah Laxhmi ; Ly, Julien et alin NeuroImage (2015, June)Detailed reference viewed: 68 (6 ULg) Towards a predictive modelling of the normal and pathological gaitVan Hulle, Romain ; Schwartz, Cédric ; Croisier, Jean-Louis et alPoster (2015, June)Detailed reference viewed: 44 (14 ULg) Occupational physicians managing workers long-term sickness absence : are they willing to cooperate with family and social insurance physicians ?Mairiaux, Philippe ; Vanmeerbeek, Marc ; Schippers, Nathalie et alConference (2015, June)Introduction In Belgium, sickness absence (SA) management implies complementary roles for family (FPs), social insurance (SIPs) and occupational physicians (OPs): FPs deliver sick notes, SIPs control SA ... [more ▼]Introduction In Belgium, sickness absence (SA) management implies complementary roles for family (FPs), social insurance (SIPs) and occupational physicians (OPs): FPs deliver sick notes, SIPs control SA benefits and OPs strive to adapt work environments to workers’ capacities. In practice however, there is little cooperation between the three physicians. This study aimed at identifying FP-OP-SIP cooperation channels in order to prevent long-term work disability. Methods The study involved two phases. (1) Using the nominal group technique, researchers from the three physician groups reached a consensus on 15 proposals to enhance inter-professional cooperation. (2) A Delphi study was conducted to validate these proposals: 61 experts representing professional groups of physicians (FP, SIP, OP), patients, government, employers and labor unions were asked to participate. A 18-items questionnaire (the 15 proposals + 3 open questions) was used in a 2-round Delphi study. Proposals were accepted if 80% of experts agreed. Results Participation rate was 77% in round 1 and 7 out of the 15 proposals were accepted. During round 2, participation rate was 94%; 2 of the remaining proposals reached agreement level. Public authorities were thus advised to invest in a) promotion of pre-return to work visit with the OP for sick-listed patients; b) a website with OPs contact data; c) joint guidelines for return to work guidance; d) joint training of the 3 physician groups; 5) safe electronic information exchange. Several proposals aiming at giving work-related information to FPs and SIPs did not reach agreement within the OPs expert group. OPs expressed concerns about their own workload and FPs or SIPs ability to understand and use those information. Discussion The need for inter-physician cooperation in disability management may exceed individual goodwill and should best be organised by public authorities. This study may be a first step in this process. [less ▲]Detailed reference viewed: 39 (11 ULg) A dynamic simulation approach to identify additional reactive reserves against long-term voltage instabilityPapangelis, Lampros ; Panciatici, Patrick; Debry, Marie-Sophie et alin Proc. of IEEE PES 2015 PowerTech conference (2015, June)A simple method is proposed to identify additional reactive reserves enabling to counteract long-term voltage instability after a large disturbance. In contrast to the many references based on power flow ... [more ▼]A simple method is proposed to identify additional reactive reserves enabling to counteract long-term voltage instability after a large disturbance. In contrast to the many references based on power flow calculations, the method resorts to dynamic simulation. The post-disturbance system evolution is simulated in the presence of time-varying shunt susceptances with specified rate of change. This allows to deal with dynamic issues such as the required speed of the additional reactive power sources, or the onset of unstable electromechanical oscillations. Furthermore, a compromise is sought between the speed of action and the volume of additional compensation. The method is demonstrated on a detailed model of the Nordic test system. [less ▲]Detailed reference viewed: 75 (15 ULg) L’externe : le Grand Méchant Loup ou l’investissement qui vaut le coup ?Crutzen, Nathalie Conference (2015, June)Detailed reference viewed: 16 (2 ULg) Importance of the reconciliation method to handle experimental data: application to a reversible heat pump / organic Rankine cycle unit integrated in a positive energy buildingDumont, Olivier ; Quoilin, Sylvain ; Lemort, Vincent Conference (2015, June)Experimental data is often the result of long and costly experimentations. Many times, measurements are used directly without (or with few) analysis and treatment. This paper therefore presents a detailed ... [more ▼]Experimental data is often the result of long and costly experimentations. Many times, measurements are used directly without (or with few) analysis and treatment. This paper therefore presents a detailed methodology to use steady-state measurements efficiently in the analysis of a thermodynamic cycle. The reconciliation method allows to correct each measurement as little as possible, taking its accuracy into account, in order to satisfy all constraints and to evaluate the most probable physical state. The reconciliation method should be used for multiple reasons. First, this method allows to close energy and mass balances exactly, which is needed for predictive models. Also, it allows determining some unknowns that are not or that cannot be measured precisely. Furthermore, it fully exploits the collected measurements with redundancy and it allows to know which sensor should be checked or replaced if necessary. An application of this method is presented in the case of a reversible HP/ORC unit. This unit is a modified heat pump which is able to work as an organic Rankine cycle by reversing its cycle. Combined with a passive house comprising a solar roof and a ground heat exchanger, it allows to get a plus energy house. In this study case, the oil mass fraction is not measured despite of its strong influence on the results. The reconciliation method allows to evaluate it. The efficiency of this method is proven by comparing the error on the outputs of steady-state models of compressor and exchangers. An example is given with the prediction of the pinch-point of an evaporator. In this case, the normalized root mean square deviation (NRMSD) is decreased from 14.3 % to 4.1 % when using the reconciliation method. This paper proves the efficiency of the method and also that the method should be considered more often when dealing with experimentation. [less ▲]Detailed reference viewed: 39 (1 ULg) Galectin-3 and Suppression of Tumorigenicity 2 measurement in participants at the “Tor des Géants”LE GOFF, Caroline ; Kaux, Jean-François ; Gergelé, Laurent et alin Radmann, A; Hedenborg, S; Tsolakidis, E (Eds.) 20th annual Congress of the EUROPEAN COLLEGE OF SPORT SCIENCE - BOOK OF ABSTRACTS0th annual Congress of the EUROPEAN COLLEGE OF SPORT SCIENCE - BOOK OF ABSTRACTS (2015, June)Introduction: Gal-3 is a carbohydrate binding lectin produced by macrophages, upregulated in hypertrophied heart, emerging as a mediator for fibrosis development and cardiac remodeling. ST2 is a family ... [more ▼]Introduction: Gal-3 is a carbohydrate binding lectin produced by macrophages, upregulated in hypertrophied heart, emerging as a mediator for fibrosis development and cardiac remodeling. ST2 is a family member of IL-1 receptors initially known for its role in immunological processes. It has a potential role in the cardiac pathogenesis. These receptors are led in cardiomyocytes and fibroblasts due to a mechanical stress. We aimed to examine the evolution of Gal-3 and ST2 in trailers who ran one of the most challenging ultra-marathon in the world: the Tor des Géants (330 km, altitude range: 24000m). Methods: Levels of plasma Gal-3 and ST2 were determined at 4 times: before the start, after 158km, at the end and 3 days after the end of the race in 33 trailers. Samples were directly centrifuged and frozen at -80°C. Gal-3 measurement was performed on the VIDAS (Biomerieux) and ST2 was analyzed with the Presage ST2 Assay (Critical Diagnostic). The reference values are <17.8ng/mL for Gal-3 and <35ng/mL for ST2. Statistica was used for the statistical analysis (ANOVA). We calculated the difference between the different time and expressed in delta: Δ1=(T2-T1)/T1*100, Δ2=(T3-T2)/T2*100, Δ3=(T4-T3)/T3*100, Δ4=(T3-T1)/T1*100, Δ5=(T4-T1)/T1*100. After that, we tried to correlate the delta between them (results= R(p-value)). Results were considered as significant with p<0.05. Results: Plasmatic levels of Gal-3 did never exceed the cut-off of 17.8ng/mL, except for 1 trailer in T2. A slight increase of levels of Gal-3 was observed at T2 (min-max:7.5-17.6ng/mL). These ones did not vary a lot at T3 (min-max:7.0- 18.8ng/mL) but return to normality at T4 (min-max:6.0-12.8ng/mL). For ST2, at T1, 12 subjects had plasmatic levels above the reference value of 35ng/ml. At T2, only 2 trailers blood samples were still in the reference interval. Indeed, a great increase of ST2 plasmatic levels observed (min-max:18.8-158.8ng/mL). A slight decrease of ST2 levels was observed at T3, but only one subject had a value below 30ng/ml (min-max:20.1-182.7ng/mL). However, a subject had still plasmatic levels above T2 values. A return to normality was observed at T4 with 16 trailers blood levels in the reference interval (min-max:12.0-56.4ng/mL). We observed an increase for Gal-3 and ST2, above the reference values only for ST2. We noted for both a decrease up to the normal values 3 days after the trail. For the correlation between deltas, we observed that Gal-3 and ST2 are correlated for each delta. Discussion: A logical correlation is observed between Gal-3 andST2 as they are involved in cardiac fibrosis and inflammation. But we do not known why it is not in the same proportion. We know that some trailers take NSAIDs and painkillers during the race. The results of this study demonstrate that this exercise was associated with biochemical abnormalities that may reflect adverse consequences on cardiac structure as fibrosis. However, ST2 values were higher, perhaps due to a mechanical stress more than a cardiac stress. Gal-3 is perhaps then more cardiospecific than ST2. [less ▲]Detailed reference viewed: 56 (1 ULg) Damage process sensitivity analysis using an XFEM-Level Set frameworkNoël, Lise ; Duysinx, Pierre ; Maute, Kurtin Proceedings of the 11th World Congress on Structural and Multidisciplinary Optimization (WCSMO-11) (2015, June)Designing efficient and lightweight structures is a key objective for many industrial applications such as in aerospace or the automotive industry. To this end, composite materials are appealing as they ... [more ▼]Designing efficient and lightweight structures is a key objective for many industrial applications such as in aerospace or the automotive industry. To this end, composite materials are appealing as they combine high stiffness and light weight. The main challenge slowing down the integration of such materials in real structures is their damage be- havior. The latter should be considered in the design process of the structures. This work focuses on developing a systematic approach to designing structures that can sustain an acceptable amount of degradation or exhibit a low sensitivity to damage. An optimization approach is chosen to achieve this goal. To deal with complex geometries and to allow for large shape modifications in the optimization process, the extended finite element method (XFEM) is advantageously combined with a level set description of geometry. The degradation of materials is modeled by using a non-local damage model, motivated by the work of James and Waisman on a density approach to topol- ogy optimization. To solve design problems with damage constraints by gradient-based optimization method, a sensitivity analysis of the damage process is developed. Damage propagation and growth is an irreversible pro- cess. Therefore, the path dependence of the structural response needs to be accounted for in the sensitivity analysis. In this paper, we present an analytical approach for efficiently and accurately evaluating the design sensitivities, considering both direct and adjoint formulations. Finally, the sensitivity analysis approach is studied with simple benchmark problems and compared with the results obtained by finite differences. [less ▲]Detailed reference viewed: 29 (8 ULg) Porcine reproductive and respiratory syndrome virus serosurveillance in the wild boar (Sus scrofa) population of Southern Belgium, 2014Thilmant, P.; Périn, F.; Tchuenkam Kamdem, Nadège et alPoster (2015, June)Detailed reference viewed: 17 (1 ULg) The Instability Strip of ZZ Ceti White DwarfsVan Grootel, Valérie ; Fontaine, G.; Brassard, P. et alin Astronomical Society of the Pacific Conference Series (2015, June), 493The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years, due to the lack of a suitable treatment for convection ... [more ▼]The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years, due to the lack of a suitable treatment for convection in these stars. We report here a detailed stability survey over the whole ZZ Ceti regime, including the low and extremely low masses. We computed to this aim 29 evolutionary sequences of DA models with various masses, chemical layering, and core compositions. These models are characterized by the so- called ML2/α=1.0 convective efficiency and take into account the important feedback effect of convection on the atmospheric structure. We computed pulsation spectra for these models with the Liège nonadiabatic pulsation code MAD, which is the only one to conveniently incorporate a full time-dependent convection treatment and, thus, provides the best available description of the blue edge of the instability strip. On the other hand, given the failure of all nonadiabatic codes to account properly for the red edge of the strip, including MAD, we tested the idea that the red edge is due to energy leakage through the atmosphere. Using this approach, we found that our theoretical ZZ Ceti instability strip accounts remarkably well for the boundaries of the empirical strip. [less ▲]Detailed reference viewed: 11 (1 ULg) Linking political discourses on science with an evolving and densely populated context: Exploring the prospects of Cultural Political EconomyCharlier, Nathan Conference (2015, June)As a PhD student, I investigate the multiple ways science is conceived and valued in a research and innovation (R&I) policy context under seismic shifts (Tyfield, 2012): I aim at analyzing and comparing ... [more ▼]As a PhD student, I investigate the multiple ways science is conceived and valued in a research and innovation (R&I) policy context under seismic shifts (Tyfield, 2012): I aim at analyzing and comparing the various political discourses about R&I in Flanders and Wallonia (the two main regions of Federal Belgium). With regards to that goal, I am currently in the process of analyzing a corpus of 33 semi-structured interviews with principal investigators of two University biotech research centers, with members of two University research management boards, and with representatives of two regional science policy advisory boards. In order to analyze this particular set of discourses, I build on various sensitizing concepts (van den Hoonard 1997) such as policy narratives (Radaelli, 2000), while following the tenets of Grounded Theory (Glaser & Strauss, 1967). However, it is, I believe, necessary to connect the specific discourses I am studying to a broader context made of institutions, of actors engaged in power relationships, of policies and policy reforms, of a specific history, of other discourses, etc. The way one build ties between a particular set of data and broader contextual aspects is key to a fruitful sociological analysis. My proposal is to explore the potentialities offered by Cultural Political Economy (Sum & Jessop, 2013), an approach concerned with “the relation between semiosis and structuration in political economy” (Sum & Jessop, 2013: X), when trying to link discourses on R&I to the context they are part of. Acknowledging the “interdependence and co-evolution of the semiotic and extra-semiotic” (ibid., 23), CPE offers heuristic tools to study the articulation of specific discourses “with technologies and agency” (ibid., 20). My communication will disclose the iterative process of discourse analysis relying on CPE, as well as its results. [less ▲]Detailed reference viewed: 14 (0 ULg) Small-Angle Scattering in Porous Solids, an overview highlighting data analysis challengesGommes, Cédric Conference (2015, June)Countless technologies and chemical processes make use of nanoporous materials: heterogeneous catalysis, including electrochemical reactions in fuel-cell electrodes, adsorption separation processes ... [more ▼]Countless technologies and chemical processes make use of nanoporous materials: heterogeneous catalysis, including electrochemical reactions in fuel-cell electrodes, adsorption separation processes, kinetically selective membrane processes, are but a few examples. Nanopores are also relevant to natural processes as diverse as the weathering of rocks and ion transport through biological membranes.[1] Small-angle scattering of x-rays (SAXS) or neutrons (SANS) is one of the few experimental methods currently available for the in situ analysis of phenomena in this type of materials at the mesoscopic scale.[e.g. 2,3] In this presentation, we briefly review some recent applications of small-angle scattering to the in situ analysis of phenomena inside mesoporous solids. A particular focus is put on the data analysis challenges, whereby the scattered intensity is converted to real-space structures with nanometer resolution. [less ▲]Detailed reference viewed: 20 (0 ULg) A finite-element solution for EEG forward modeling with realistic individual head modelsZiegler, Erik; Geuzaine, Christophe ; Phillips, Christophe Poster (2015, June)Detailed reference viewed: 24 (6 ULg) Macroscopic analysis of interaction models for the provision of flexibility in distribution systemsMathieu, Sébastien ; Ernst, Damien ; Cornélusse, Bertrand in Proceedings of the International Conference on Electricity Distribution, CIRED 2015 (2015, June)To ease the transition towards the future of distribution grid management, regulators must revise the current interaction model, that is, the set of rules guiding the interactions between all the parties ... [more ▼]To ease the transition towards the future of distribution grid management, regulators must revise the current interaction model, that is, the set of rules guiding the interactions between all the parties of the system. Five interaction models are proposed, three of them considering active network management. This paper evaluates the economic efficiency of each model using macroscopic representation of the system, by opposition to more techniques requiring a complete picture of the system. The interaction models are simulated on the horizon 2015-2030. Results show that for the first five years all the models provide similar economic efficiency. For the remaining ten years, interaction models implementing active network management provide up to a 10% higher economic efficiency. [less ▲]Detailed reference viewed: 133 (22 ULg) Genetic depletion of the dual specificity protein phosphatase DUSP3 promotes LLC Lung tumour metastasisVandereyken, Maud ; Amand, Mathieu; Van Overmeire, Eva et alPoster (2015, June)DUSP3, also called Vaccinia-H1 Related (VHR) is a small dual specificity phosphatase dephosphorylating both tyrosine and serine/threonine phosphorylated residues. DUSP3 plays an important role in cell ... [more ▼]DUSP3, also called Vaccinia-H1 Related (VHR) is a small dual specificity phosphatase dephosphorylating both tyrosine and serine/threonine phosphorylated residues. DUSP3 plays an important role in cell cycle regulation and is up-regulated in several human cancers. The physiological role of this phosphatase is, however, poorly understood. We have recently generated a DUSP3 knockout mouse by homologous recombination. The obtained mice have no spontaneous phenotype or pathology. However, DUSP3 deficiency prevented neo-vascularization of subcutaneously transplanted Matrigel plugs and Lung Lewis Carcinoma (LLC) tumours, suggesting an involvement of DUSP3 in tumour angiogenesis. Considering the importance of angiogenesis in metastatic formation, our study aimed to investigate the role of DUSP3 in metastatic dissemination. To do so, we used the LLC experimental metastasis model that shortcuts the intravasation/extravasation processes by injecting intravenously the LLC and the B16 (metastatic melanoma cell line) cells. Surprisingly, LLC, but not B16, lung metastasis developed twice faster in DUSP3-KO than WT mice. The enhanced LLC metastatic growth in DUSP3-/- mice was transferable to WT mice via DUSP3-/- bone marrow adoptive transfer, suggesting an involvement of the hematopoietic compartment in the observed phenotype. This was confirmed by a higher infiltration of neutrophils and macrophages in the lungs of DUSP3-KO compared to WT mice after LLC injection. This infiltration was correlated with higher expression of the chemokine receptor CCR2 in LLC-bearing DUSP3-KO lungs macrophages. Interestingly, LLC, but not B16 cells, were found to secrete high level of CCL2/MCP1, the CCR ligand chemokine. In line with this observation, we found that DUSP3-/- bone marrow derived-macrophages have a higher migration potential in response to LLC, but not B16, -conditionned medium. Altogether, our results suggest that DUSP3 plays an important role in metastatic dissemination/growth by a mechanism involving the control of CCR2-CCL2 chemoattraction axis in macrophages. [less ▲]Detailed reference viewed: 13 (2 ULg) O serogroups of enteropathogenic (EPEC) and Shigatoxigenic (STEC) Escherichia coli from <1 month-old diarrhoeic calves in WalloniaFakih, Ibrahim ; Duprez, Jean-Noël ; Thiry, Damien et alPoster (2015, June)Detailed reference viewed: 24 (0 ULg) “Sublime Gaps: the Absence of Closure in the Metaphysical Detective Story”Dechene, Antoine Conference (2015, June)Detailed reference viewed: 19 (2 ULg) Modeling inflorescence development in tomatoPérilleux, Claire ; Lobet, Guillaume ; Tocquin, Pierre Conference (2015, June)Detailed reference viewed: 19 (2 ULg) Empowering NGS technologies for the study and diagnostic of plant viruses - European COST Action FA1407Massart, Sébastien ; Gentit, Pascal; Olmos, Antonio et alPoster (2015, June)Detailed reference viewed: 11 (0 ULg) “Monsieur Pain o cuando el grotesco y lo sublime se invitan en la novela policiaca”Dechene, Antoine Conference (2015, June)Detailed reference viewed: 10 (0 ULg) Speckle interferometry in the long-wave infrared for combining holography and thermography in a single sensor. Applications to nondestructive testing: the FANTOM projectGeorges, Marc in Lehmann, Peter; Osten, Wolfgang; Albertazzi, Armando (Eds.) Optical Measurement Systems for Industrial Inspection IX (2015, June)Speckle interferometry in the thermal wavelengths range (long-wave infrared, 8-14 μm), combining a CO2 laser and recording with an uncooled microbolometer camera is presented. In this wavelength range ... [more ▼]Speckle interferometry in the thermal wavelengths range (long-wave infrared, 8-14 μm), combining a CO2 laser and recording with an uncooled microbolometer camera is presented. In this wavelength range specklegrams are affected by the thermal radiation emitted by objects at room temperature. This allows simultaneously capturing temperature and surface shape information about objects. The FANTOM project is based on this concept and an instrument was developed to take advantage of this natural data fusion. It has been used in a variety of nondestructive testing applications where both information are useful, specifically in aeronautical composite structures. [less ▲]Detailed reference viewed: 19 (0 ULg) The ICE protocol for ecological continuity: a new tool to evaluate the upstream fish passage success at physical barriersOvidio, Michaël ; Larinier, Michel; Burgun, Vincent et alConference (2015, June)The recording and classification of obstacles that can interfere with the movements and migrations of fish is critical information to plan river restoration program. To date a major problem is to ... [more ▼]The recording and classification of obstacles that can interfere with the movements and migrations of fish is critical information to plan river restoration program. To date a major problem is to determine the potential effect of each obstacle and to select the problematic sites that should be improved to restore longitudinal connectivity (construction of fish passage facilities, removal or modification of the obstacles). Fish passage success about an obstacle is complex and depends on the hydraulic conditions over and at the foot of the obstacle in relation to swimming and leaping capabilities of the fish species concerned. This selection and classification is too often biased because managers lack information’s on the fish capabilities to leap physical obstacles. The need for a simple, reliable and standardised assessment method for use by a wide range of environmental stakeholders rapidly became evident. We responded to the challenge and developed the ICE protocol as the basis for the required ecological-continuity assessment method, particularly in the context of the European Water Framework Directive implementation. The ICE protocol coordinated by ONEMA is based on an integration of the topographical and hydraulic characteristics of obstacles with the physical capabilities (swimming, jumping or crawling) of the fish species analysed. It requires the gathering of standardised descriptive variables on each obstacle. The result of the analysis is an indication on the risks of a structure constituting a more or less severe obstacle (5 classes) for a given fish species (n=47) or group of species. Particular attention was paid to the practical aspects of the method (time required and necessary human resources) to facilitate its use in a wide variety of situations and areas. Each procedure is presented as a flow chart to assist in decision-making, thus making the protocol easy to use for a wide range of people. [less ▲]Detailed reference viewed: 63 (5 ULg) Nonlinear ground vibration identification of an F-16 aircraft - Part 2: Understanding Nonlinear Behaviour in Aerospace Structures Using Sine-sweep TestingDossogne, Tilàn ; Noël, Jean-Philippe ; Grappasonni, Chiara et alin Proceedings of the International Forum on Aeroelasticity and Structural Dynamics (2015, June)Although they are generally modelled as linear systems, aircraft structures are known to be prone to nonlinear phenomena. A specific challenge encountered with fighter aircraft, besides aeroelastic ... [more ▼]Although they are generally modelled as linear systems, aircraft structures are known to be prone to nonlinear phenomena. A specific challenge encountered with fighter aircraft, besides aeroelastic nonlinearity, is the modelling of the wing-to-payload mounting interfaces. For large amplitudes of vibration, friction and gaps may be triggered in these connections and markedly impact the dynamic behaviour of the complete structure. In this series of two papers, the nonlinear dynamics of an F-16 aircraft is investigated using rigorous methods applied to real data collected during a ground vibration test campaign. The present work focuses on the analysis of sine-sweep measurements in order to get an insightful understanding about the nonlinear behaviour of the aircraft. To this extent, restoring force surface and wavelet transform methods are applied both on the collected GVT data and simulation results performed on a simple numerical model of the F-16 wing and its payload. [less ▲]Detailed reference viewed: 71 (12 ULg) Auroral Morphologies of Jupiter and SaturnGrodent, Denis Conference (2015, May 31)We review the principal differences and similarities of the morphologies of Jupiter and Saturn's auroral emissions. We then show some examples of UV images that are expected to be acquired with Cassini ... [more ▼]We review the principal differences and similarities of the morphologies of Jupiter and Saturn's auroral emissions. We then show some examples of UV images that are expected to be acquired with Cassini UVIS at Saturn and Juno UVS at Jupiter. [less ▲]Detailed reference viewed: 14 (1 ULg) Comparing central western Europe Mesolithic and Neolithic plant processing microwear on flint toolLinton, Jimmy ; Guéret, Colas; Gassin, BernardConference (2015, May 30)Detailed reference viewed: 22 (0 ULg) Quelles caractéristiques du passage à la retraite ont un impact sur la cognition du sujet âgé ? Résultats de la cohorte AMIGrotz, Catherine ; Matharan, Fanny; Amieva, Hélène et alConference (2015, May 29)Detailed reference viewed: 19 (0 ULg) Approche processuelle de la dépression : Impact de processus psychologiques l'activation ou l'évitement en fonction du sexeWagener, Aurélie Conference (2015, May 29)La dépression est caractérisée par des symptômes affectifs, cognitifs et somatiques. Elle est également caractérisée par une diminution du niveau d’engagement dans des activités ce qui peut être ... [more ▼]La dépression est caractérisée par des symptômes affectifs, cognitifs et somatiques. Elle est également caractérisée par une diminution du niveau d’engagement dans des activités ce qui peut être conceptualisé comme de l’évitement comportemental (symptôme comportemental). Il est en effet fréquent que les patients dépressifs s’engagent de moins en moins dans des activités qui leur plaisaient auparavant (voir des amis, etc.) Ce faible niveau d’activités maintient leur humeur dépressive. Cette relation entre dépression et faible niveau d’engagement dans des activités est bien établie dans la littérature scientifique mais les relations entre les processus cognitifs sous-jacents sont encore mal connues. Selon les modèles théoriques de la dépression (Beck, 2008; Lewinsohn, 1985; Watkins, 2009), cinq types de processus psychologiques (PP) sont impliqués dans la symptomatologie dépressive : les pensées négatives répétitives, les stratégies de régulation émotionnelle non-adaptées, un faible niveau de satisfaction environnementale, une image de soi négative et une tendance à l’inhibition. Nous faisons l’hypothèse que ces PP pourraient être les facteurs explicatifs de l’évitement comportemental. Par ailleurs, nous faisons également l’hypothèse que d’autres PP pourraient être considérés comme des facteurs explicatifs de l’activation comportementale : les stratégies de régulation émotionnelle adaptées, un haut niveau de satisfaction environnementale, une image de soi positive, une tendance à l’approche et un concept de soi clair. Ces PP consisteraient en des facteurs protecteurs de la dépression. Dès lors, notre objectif est d’évaluer les liens entre évitement comportemental, activation comportementale et PP. Pour ce faire, en nous basant sur le modèle de Kinderman (2013), nous avons élaboré un modèle conceptualisant l’influence que peuvent avoir les PP précités sur, d’une part, l’évitement comportemental et, d’autre part, l’activation comportementale. De plus, l’étude évalue l’adéquation de ce modèle de façon à comparer les hommes et les femmes. 477 adultes issus de populations cliniques et non-cliniques (119 hommes, 358 femmes, âge moyen = 34,25, ET = 11,85) ont complété une étude en ligne évaluant les PP (pensées négatives répétitives, stratégies de régulation émotionnelles, satisfaction environnementale, image de soi, tendance à l’inhibition/l’approche, clarté du concept de soi), l’évitement comportemental et l’activation comportementale. Différents questionnaires évaluaient chacun de ces PP. Dès lors, des scores factoriels ont été réalisés pour représenter chaque PP. Les résultats préliminaires issus d’analyses factorielles confirmatoires semblent révéler des différences entre les hommes et les femmes. Pour les hommes, une image de soi négative, des stratégies de régulation émotionnelle non-adaptées et un faible niveau de satisfaction environnementale sont liés à l’évitement comportemental alors qu’un haut niveau de satisfaction environnementale et une image de soi positive sont liés à l’activation comportementale. Pour les femmes, un faible niveau de satisfaction environnementale, des stratégies de régulation émotionnelle non-adaptées et des pensées négatives répétitives sont liées à l’évitement comportemental alors qu’un haut niveau de satisfaction environnemental et une image de soi positive sont liées à l’activation comportementale. La collecte des données étant toujours en cours, les résultats globaux seront présentés durant le congrès. Les implications cliniques de ces résultats seront discutées telles que la pertinence de travailler sur le niveau de satisfaction environnementale. [less ▲]Detailed reference viewed: 61 (3 ULg) Du témoignage d'une cérémonie à l'organisation d'une révolution médiatique du pouvoir : les pratiques du livre de fête à l'aube de la Première modernitéRusch, Arnaud Conference (2015, May 29)Detailed reference viewed: 10 (0 ULg) De l’ordre répressif étatique à celui de la Cour pénale internationale : la sensibilité du juge de Strasbourg à la gravité des faits en causeDeprez, Christophe Conference (2015, May 29)Cette présentation PowerPoint a servi de support à une communication orale dans le cadre de l'édition 2015 de la Conférence des Assistants en droit de Belgique (ACCA), organisée le 29 mai 2015 par l ... [more ▼]Cette présentation PowerPoint a servi de support à une communication orale dans le cadre de l'édition 2015 de la Conférence des Assistants en droit de Belgique (ACCA), organisée le 29 mai 2015 par l'Université catholique de Louvain. [less ▲]Detailed reference viewed: 20 (2 ULg) Unravelling Cemip expression and functions in the auditory portion of the inner ear.Czajkowski, Amandine ; Chariot, Alain ; Delacroix, Laurence et alPoster (2015, May 29)The inner ear is a complex organ composed of the vestibular system – which is the balancing system – and the cochlea – which is the earing system. The cochlea is a coiled shape organ composed of three ... [more ▼]The inner ear is a complex organ composed of the vestibular system – which is the balancing system – and the cochlea – which is the earing system. The cochlea is a coiled shape organ composed of three main structures: the spiral ligament sitting on top of the stria vascularis, the organ of Corti with sensory hair cells and supporting cells and the spiral ganglion composed of neurons and glial cells. After an auditory stimulus, the sound wave progresses in the scala media filled with endolymph and induces a stimulation of sensory hair cells. These cells then transmit the information to the spiral ganglion neurons connected to them. Of course, the correct ionic homeostasis of endolymph is required for a good sound wave transmission. This homeostatic function is assured by the stria vascularis and the spiral ligament. The alteration of one of the structures mentioned before induces deafness. Currently, numerous genes have been associated to this kind of hearing loss. In the present work, we focus our attention Cemip – also known as KIAA1199 – that has been associated to human hereditary neurosensory deafness. Indeed, three missense mutations consisting in non-synonymous amino acid changes (R187L, R187H and H783Y) have been associated to this form of deafness. Therefore we would like to understand the role of Cemip in the cochlea. For that we have analysed Cemip mRNA pattern of expression by in situ hybridization at different developmental stages on cochlear sections. It seems Cemip mRNA is not present in the auditory portion of the inner ear at early embryonic stage 14 (E14) while it is largely present at E17 in the spiral ganglion, in supporting cells of the organ of Corti and in the spiral ligament. This expression is maintained post-nattily until P7. At P21 the expression is restricted to the spiral lamina - an osseous structure surrounding the spiral ganglion. Our on going work is aimed at revealing the biological role of Cemip in the cochlea in conditional knock-out mice. [less ▲]Detailed reference viewed: 22 (3 ULg) Antitrust and The challenge of policing « moligopolists »Petit, Nicolas Conference (2015, May 29)Detailed reference viewed: 29 (2 ULg) Towards an experiment based protocol for extracting and identifying residuesCnuts, Dries ; Rots, Veerle Conference (2015, May 29)Residue analysis has recently become a widely applied method in reconstructing the lifecycle of prehistoric stone tools. The identification of residues is traditionally based on the distinctive ... [more ▼]Residue analysis has recently become a widely applied method in reconstructing the lifecycle of prehistoric stone tools. The identification of residues is traditionally based on the distinctive morphologies of the residue fragments by means of light microscopy. The majority of residue fragments, however, tend to have an amorphous structure and are therefore not easy to identify. In addition, some residue categories can only be detected by using transmitted light microscopy, which requires the extraction of residues from the tool’s surface. Yet another challenge is to determine whether the residues were deposited on the tool’s surface as a result of use or due to other processes. Here we present the results of an experimental study that addresses these methodological issues. Stone tools from a new experimental reference collection were used to test 6 different analytical methods: the observation of residues on stone tools with incident light microscopy, dry sampling using tweezers and brushes, wet sampling with micropipettes using distilled water and a tri-mixture of acetonitrile, ethanol and water, and extraction with an ultrasonic scaler or bath. The experiments demonstrate that the choice of a particular extraction procedure may influence the amount and types of residues that are extracted. This implies that the analytical method has an impact on the results of a residue analysis. Building on these data, we designed a new protocol, which was subsequently submitted to blind testing in order to test its accuracy and precision. Certain key attributes were also identified that may prove useful in distinguishing between use-related and natural residues. We discuss the importance of adapting analytical protocols to the research question of the study. [less ▲]Detailed reference viewed: 32 (5 ULg) Prevalence, location and concurrent diseases in dogs with ultrasonographic abdominal cystic lymph nodesLiotta, Annalisa Pia ; Heimann, Marianne; Billen, Frédéric et alConference (2015, May 29)Detailed reference viewed: 50 (14 ULg) Toward a more precise terminology for impact damage and an improved understanding of hunting weapons: First results from a large scale systematic experimentCoppe, Justin ; Rots, Veerle Conference (2015, May 29)Projectile points have recently taken an important place in debates on the complexity of Palaeolithic human behaviour. While the appearance of hunting weapons in the archaeological record was an important ... [more ▼]Projectile points have recently taken an important place in debates on the complexity of Palaeolithic human behaviour. While the appearance of hunting weapons in the archaeological record was an important element in the past, current discussions focus a lot on the appearance of particular hunting methods. Distinctions are made between simple and complex weaponry, the latter assumed to be linked with modern humans only. While most of the identifications of hunting weapons in the archaeological record rely on the examination of so-called diagnostic impact damage, no reliable reference yet exist for distinguishing between hunting methods. We present the first results of a large-scale and systematic experiment that intends to address hunting weapons in a systematic way. A thorough survey of the literature has highlighted some existing ambiguity in current terminological frameworks for describing impact fractures. Based on our experiments, we propose some attributes that may be relevant for improving these terminologies. Attention will also be devoted to the design and conceptual framework of our experimental program and to some first results concerning the essential variables influencing damage formation. The overall goal is to improve our understanding of the different fracture phenomena and their variability in order to enhance the reliability of the identification of hunting weapons and perhaps of their projecting mode. [less ▲]Detailed reference viewed: 29 (3 ULg) Optimization of a PGSS process for a fenofibrate lipid-based solid dispersion formulationPestieau, Aude ; Krier, Fabrice ; Lebrun, Pierre et alConference (2015, May 29)Detailed reference viewed: 23 (5 ULg) Parental and romantic attachments in teen datings : different meanings in boys' and girls' intimacyCourtain, Audrey ; Lepas, Jennifer; Boulard, Aurore et alPoster (2015, May 28)First proposing a relational understanding of the child’s very first years, attachment theory has since then been taken into consideration in friendships and romantic relationships. Indeed, the internal ... [more ▼]First proposing a relational understanding of the child’s very first years, attachment theory has since then been taken into consideration in friendships and romantic relationships. Indeed, the internal working models (IWM) built upon early interactions are to be used on and on in many other situations as guidelines to understand what is going on for the self, this particular other and their specific relationship. Different attachment styles are thus likely to develop: secure or insecure (anxious/preoccupied, avoidant/dismissive, fearful). Considering teen dating, attachment is deeply involved, especially for two reasons: first, a certain questioning, but also re-actualization, of the attachment to parents; second, a new kind of attachment, meaning the one to the romantic partner. These elements lead us to test hypotheses linking attachment to parents and attachment to romantic partners, but also linking these attachments to some teen dating characteristics, such as the age when first dating, the number of love relationships, the longest-lasting love relationship and the fear of intimacy. Our hypothesis was tested among 283 teenagers (mean age = 17.43) with two self-administered questionnaires (the Behavioral Systems Questionnaire and the Fear of Intimacy Scale). Our statistical analyses were made of Pearson Chi², Anova and Post-Hoc Fisher (LSD). We see three types of interesting results. First, there is a significant relationship between attachment (parental and romantic attachments) and the number of love relationships and the fear of intimacy. Second, these relationships are differently established once considered the attachment modalities. Third, gender differences appear, girls looking more influenced by their attachment style than boys. [less ▲]Detailed reference viewed: 50 (6 ULg) Is Büchi's theorem useful for you?Rigo, Michel Conference (2015, May 28)Almost a century ago, Presburger showed that the first order theory of the natural numbers with addition is decidable. Following the work of Büchi in 1960, this result still holds when adding a function ... [more ▼]Almost a century ago, Presburger showed that the first order theory of the natural numbers with addition is decidable. Following the work of Büchi in 1960, this result still holds when adding a function $V_k$ to the structure, where $V_k(n)$ is the largest power of $k\ge 2$ diving $n$. In particular, this leads to a logical characterization of the $k$-automatic sequences. During the last few years, many applications of this result have been considered in combinatorics on words, mostly by J. Shallit and his coauthors. In this talk, we will present this theorem of Büchi where decidability relies on finite automata.Then we will review some results about automatic sequences or morphic words that can be proved automatically (i.e., the proof is carried on by an algorithm). Finally, we will sketch the limitation of this technique. With a single line formula, one can prove automatically that the Thue-Morse word has no overlap but, hopefully, not all the combinatorial properties of morphic words can be derived in this way. [less ▲]Detailed reference viewed: 37 (5 ULg) Quelle place accorder aux écritures de la réception dans le contexte de la formation initiale? Du comportement des futurs enseignants face à des médiations de la lecture à l'élaboration de dispositifs de formationDe Croix, Séverine ; Ledur, DominiqueConference (2015, May 28)L’exploitation des écritures de la réception en formation initiale des enseignants fait aujourd’hui l’objet d’un large consensus (Joole, 2013 ; Chabanne & Dufays, 2011; Mazauric, Fourtanier & Langlade ... [more ▼]L’exploitation des écritures de la réception en formation initiale des enseignants fait aujourd’hui l’objet d’un large consensus (Joole, 2013 ; Chabanne & Dufays, 2011; Mazauric, Fourtanier & Langlade, 2011 ; Vanhulle & Schillings, 2004). Nous souhaitons nous interroger sur les moyens, les objectifs et les effets attendus de cette exploitation (axe 4 de l’appel à communications). Le présent projet porte, dans un premier temps, sur l’observation des réactions d’une centaine de futurs enseignants de français du secondaire, tous niveaux confondus, face à un corpus de médiations écrites de la lecture, produites par des élèves de 12 à 18 ans, lecteurs experts et en difficulté. Ces écrits relèvent de genres diversifiés (journaux de lecture, notes critiques, traces collectées à l’occasion d’un dévoilement progressif, réponses à des questions, etc.) et de statuts différents (écrits de travail ou productions finales susceptibles d’être évaluées). Les consignes d’analyse devaient conduire les étudiants à repérer les éventuelles difficultés des lecteurs (ou leurs réussites), à reconstruire les tâches, à relever différents positionnements face aux textes, etc. Nos constats mettent notamment en évidence une tendance à investir ces écrits de façon normative (prédominance des difficultés du lecteur, notamment linguistiques, au détriment d’une prise en compte des difficultés générées par les textes et/ou les tâches scolaires) et une faible conscience de la complexité de l’activité de compréhension/interprétation. L’analyse des données collectées à l’occasion de ce travail incite, dans un deuxième temps, à privilégier quatre directions pour apprendre aux futurs maitres de lecture à lire des écrits de la réception et pour les amener par ce biais à développer des compétences et gestes professionnels en didactique de la lecture littéraire : modéliser l’activité de compréhension/interprétation, identifier les éventuelles difficultés de lecture, sélectionner des textes pour la classe et les associer à des médiations adaptées, percevoir les caractéristiques et les visées des tâches (y compris anticiper les éventuels malentendus générés par celles-ci et organiser leur progression). Ces axes d’intervention seront illustrés par quelques exemples de dispositifs de formation. [less ▲]Detailed reference viewed: 23 (1 ULg) Video Game Beliefs Questionnaire (VGBQ): creation and psychometric propertiesBurnay, Jonathan ; Laroi, Frank Poster (2015, May 28)Detailed reference viewed: 13 (0 ULg) Fully automated electrophoretically mediated microanalysis system for CYP1A1 activity monitoringFarcas, Elena ; Servais, Anne-Catherine ; Lamalle, Caroline et alConference (2015, May 28)In order to evaluate the potentiality of capillary electrophoresis for CYP1A1 activity monitoring, an in-line method was developed with the well-known 7-ethoxycoumarin substrate. The electrophoretically ... [more ▼]In order to evaluate the potentiality of capillary electrophoresis for CYP1A1 activity monitoring, an in-line method was developed with the well-known 7-ethoxycoumarin substrate. The electrophoretically mediated microanalysis approach was used with CYP1A1 supersomes to provide a rapid and fully automated method. The in-line homogenous enzyme assay was performed in physiological conditions (pH 7.4), whereas a MEKC buffer was used as background electrolyte. In order to reduce the analysis time, the short end injection was performed. Firstly a plug containing CYP1A1 supersomes was hydrodynamically injected into a fused silica capillary, followed by a plug of co-factor (NADPH) and substrate (7-ethoxycoumarin) and finally another plug of CYP1A1 (sandwich mode). The experimental conditions were finely investigated and tuned by design of experiment methodology. The metabolization rate measured in the optimized conditions was comparable with the one obtained after off-line metabolization. Finally, inhibition studies were conducted and a significant decrease of 7-hydroxycoumarin formation was observed using apigenin as CYP1A1 potent inhibitor. [less ▲]Detailed reference viewed: 24 (4 ULg) Borderline Personality Disorder through the Rorschach testRommes, Jennifer; Englebert, Jérôme ; Blavier, Adelaïde Poster (2015, May 28)Detailed reference viewed: 38 (1 ULg) Tool use and hafting in the Middle Palaeolithic of Northern Africa An on-going use-wear analysis on the Mousterian/Aterian assemblages of Ifri n’Ammar (Morocco)Tomasso, Sonja ; Rots, Veerle Conference (2015, May 28)The so-called “Aterian Culture” has received attention since the early days of prehistoric archaeology in Northern Africa. Several definitions were proposed, which triggered a debate around this cultural ... [more ▼]The so-called “Aterian Culture” has received attention since the early days of prehistoric archaeology in Northern Africa. Several definitions were proposed, which triggered a debate around this cultural concept. In particular the presence of the tanged tools was a crucial element in these debates and the tangs were considered to potentially represent the earliest indications of hafting, or at least of intentional morphological adaptations in view of hafting. In contrast to numerous typological and technological studies of Aterian and Mousterian assemblages, use-wear analyses have been scarce up until today. However, for a better understanding of several aspects of these Middle Palaeolithic “cultures”, functional data needs to be taken into consideration. Given the issue of tanged pieces, the potential of such detailed studies on production, hafting and use is high. In this paper, the first results will be presented of an on-going use-wear analysis on tools from the Aterian/Mousterian assemblages of Ifri n’Ammar. This rock shelter presents an ideal case thanks to its particularly rich and well preserved stratigraphy. Around 200 artefacts have been selected up to now, based on their degree of preservation and without restrictions on the level of the tool types. Artefacts were examined macroscopically and microscopically in a search for evidence of their production, hafting and use and an experimental program was set up. Archaeological interpretations are based on new experiments, as well as on the existing large experimental reference collection available at TraceoLab at the University of Liège. The long-term goal of the study is to use a functional approach to answer questions related to lithic assemblage variability. At Ifri n’Ammar, it is clear that the tangs occur on a variety of tools. Due to the presence of tangs in the Aterian and their absence in the Mousterian, it can be hypothesized that there was a shift in hafting techniques between the two cultures/periods. In order to understand whether this change was triggered by functional, cultural, or environmental factors, more functional data is clearly needed. [less ▲]Detailed reference viewed: 23 (1 ULg) Life cycle assessment of biobased chemical building blocks made from European waste streamsGroslambert, Sylvie ; Léonard, Angélique Poster (2015, May 28)Detailed reference viewed: 17 (1 ULg) USE OF SIMPLE AND COMPLEX ANALYTICAL TOOLS TO DETECT POOR QUALITY MEDICINES: CASE OF RWANDAHabyalimana, Védaste ; Dispas, Amandine ; Sacre, Pierre-Yves et alConference (2015, May 28)Detailed reference viewed: 15 (6 ULg) Le donné phénoménal de Tim CraneGauvry, Charlotte Conference (2015, May 28)Detailed reference viewed: 15 (0 ULg) Maternal representations, social context and substance abuseHalin, Stéphanie ; Combe, Samantha; Glowacz, Fabienne et alPoster (2015, May 28)Detailed reference viewed: 21 (7 ULg) Heterogeneity of multitasking abilities in schizophrenia.Laloyaux, Julien ; Van der Linden, Martial ; Laroi, Frank Conference (2015, May 28)Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular for those activities requiring multitasking capacities. Multitasking refers to ... [more ▼]Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular for those activities requiring multitasking capacities. Multitasking refers to activities (e.g. preparing a meal) where the person has to: (a) carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; (b) define the tasks’ targets; (c) and face unexpected problems during the realization of these tasks. Moreover, schizophrenia is characterized by a great heterogeneity in regard to their everyday life difficulties and cognitive functioning. At present, patients’ multitasking capacities have not been adequately examined in the literature due to an absence of suitable assessment strategies. We thus recently developed a computerized real-life activity task designed to take into account the complex and multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting (i.e. the Computerized Meeting Preparation Task, CMPT). The aim of this study was to examine the multitasking abilities in persons diagnosed with schizophrenia and in particular the existence of subgroups of patients in regard to their performances on cognitive measures and on the CMPT. Sixty-two patients diagnosed with schizophrenia and 39 paired healthy controls completed the CMPT and a cognitive battery. The results reveal that the CMPT possesses good sensitivity and suggest three underlying constructs of multitasking (Memory, Planning and Intent), which were found to be underpinned by several cognitive functions and multitasking aspects. Moreover, cluster analyses revealed subgroups of patients differing in terms of their cognitive and CMPT performances. Taken together, these results show the need for a cognitive model of multitasking abilities in persons diagnosed with schiozphrenia. Taken together, this cognitive model and the CMPT, could be a good basis for cognitive interventions of multitasking abilities in schizophrenia. Finally, the results underline the heterogeneity of schizophrenia. [less ▲]Detailed reference viewed: 17 (0 ULg) An ALE meta-analysis on the neural correlates of personal goal processing during episodic future thoughts and mind-wanderingStawarczyk, David ; D'Argembeau, Arnaud Conference (2015, May 28)The ability to project oneself into the future is a multi-determined mental faculty that depends on various cognitive processes supported by an extended set of brain regions. The aim of the present study ... [more ▼]The ability to project oneself into the future is a multi-determined mental faculty that depends on various cognitive processes supported by an extended set of brain regions. The aim of the present study was to examine a crucial component of future thinking—personal goal processing—and to determine its neural correlates during both experimentally directed mental time travel towards the future and mind-wandering, a form of spontaneous thoughts characterized by a prospective bias towards upcoming events. To address this question, we performed three distinct ALE meta-analyses of brain imaging studies on episodic future thinking, mind-wandering, and personal goal processing. We then examined the commonalities and differences in brain activity between these three areas of research. The results showed that the three domains activated a common set of brain regions within the default network including the posterior inferior parietal cortex, posterior cingulate cortex, lateral temporal lobe, and, most notably, the medial prefrontal cortex. Differences in activation were also observed, and the medial prefrontal cortex was more activated during personal goal processing than the other two domains. These findings suggest that the medial prefrontal cortex mediates the processing of personal goals during both episodic future thinking and mind-wandering. [less ▲]Detailed reference viewed: 67 (1 ULg) QUALITY EVALUATION OF PARACETAMOL AND AMOXICILLINE AS PART OF INVESTIGATION OF THE OFFICIAL AND PERIPHERAL DRUG MARKET IN KINSHASA-DRCKalenda Tshilombo, Nicodème ; Mbinze Kindenge, Jérémie ; Kalenda, T.D. et alConference (2015, May 28)Detailed reference viewed: 20 (5 ULg) Psychopathy and emotions: would emotional distancing make more efficient in cognitive tasks?Grandjean, Sylvie; Dehon, Hedwige ; Blavier, Adelaïde et alPoster (2015, May 28)Detailed reference viewed: 21 (1 ULg) "Needs-supplies fit and behavioural outcomes: the mediating role of organizational identification"Travaglianti, Fabrice ; Babic, Audrey ; Hansez, Isabelle Conference (2015, May 28)Detailed reference viewed: 21 (9 ULg) The hot Jupiter WASP-­121 b: A planet heading towards its doomDelrez, Laetitia Conference (2015, May 28)We present here the discovery by the WASP-South survey, in close collaboration with the Euler and TRAPPIST telescopes, of WASP-121 b, a new remarkable short-period transiting hot Jupiter. WASP-121 b is a ... [more ▼]We present here the discovery by the WASP-South survey, in close collaboration with the Euler and TRAPPIST telescopes, of WASP-121 b, a new remarkable short-period transiting hot Jupiter. WASP-121 b is a very inflated (1.86 Rjup) Jupiter-mass (1.18 Mjup) planet that transits every 1.27 days a bright active F6V star. A notable property of WASP-121b is that its orbital semi-major axis is only 15% larger than its Roche limit, which suggests that the planet might be close to tidal disruption. Furthermore, its large size and extreme irradiation (7.1 10^9 erg s^-1 cm^-2) make it an excellent target for atmospheric studies via secondary eclipse observations. Using the TRAPPIST robotic telescope, we indeed detect its thermal emission in the z’-band at better than ~4sigma, the measured occultation depth being 603+-130 ppm. This measurement is a first for a ground-based 60cm telescope. Finally, from a measurement of the Rossiter-McLaughlin effect with the CORALIE spectrograph, we infer a sky-projected spin-orbit angle of 257.8+-6 deg. This result indicates a significant misalignment between the spin axis of the host star and the orbital plane of the planet, the planet being in a nearly polar orbit. [less ▲]Detailed reference viewed: 27 (6 ULg) Romantic relationship and delinquency : which desistance factor ?Puglia, Rosa ; Lepas, Jennifer; Glowacz, Fabienne Poster (2015, May 28)A large number of studies (Stouthamer-Loeber, Loeber, Wei, Farrington & Wikstrom, 2002) have shown that the quality of parent-child relationship influences delinquency behavior during adolescence. So, the ... [more ▼]A large number of studies (Stouthamer-Loeber, Loeber, Wei, Farrington & Wikstrom, 2002) have shown that the quality of parent-child relationship influences delinquency behavior during adolescence. So, the poorer the quality of relationship between a parent and his child is, the higher the probability that the child adopts delinquent behavior. However, recent studies (Giordano et al., 2002 ; Laub et al., 1998 ; Meeus & al., 2004 ; Woordward et al., 2002) have questioned the persistence of this association when people involved in a romantic relationship. These research have shown that quality of parent-child relationship predict delinquency in adolescents and young adults who do not have an intimate partner. But in adolescents and young adults who have an intimate partner, quality of parent-child relationship becomes obsolete. To be involved in an intimate relationship leads to less delinquency. Furthermore, results are concordant with research about desistance from delinquency that have shown that marriage leads to less criminality (Forrest & Hay, 2011 ; Sampson & Laub, 1993). These studies (Meus & al., 2004 ; Sampson & Laub, 1993) specify that it is quality of relationship rather than simply being in a romantic relationship that have an impact on desistance from delinquency. From empirical research conducted with adolescents and young adults (N=283) aged from 16 to 22 years old, and from a clinical research, we have explored links between parental attachment, romantic attachment and delinquency. We wondered if romantic attachment promotes desistance from delinquency whatever parental attachment. Behavioral System Questionnaire (Wehner & Furman, 1999) and self-reported delinquency scale (Born & Gavray, 1994) have used in this context. It appears that most of the participants have been involved in a significant romantic relationship. This romantic relationship is mainly characterized by a secure attachment. So, it leads to less deviant behaviors. On the other hand, parental attachment does not lead to less deviant behaviors. It also appears that attachment style that one develops towards one’s parent is not unchangeable. Romantic relationship during adolescence and adulthood can bring emotional and relational modifications. [less ▲]Detailed reference viewed: 28 (1 ULg) The more you know...........various approaches in the analysis of tools from Liang Bua, Flores IndonesiaLentfer, Carol ; Stephenson, Birgitta; Cnuts, Dries et alConference (2015, May 28)Chipped stone flakes from sedimentary deposits from the Liang Bua site, Flores, Indonesia have been found in association with faunal remains and skeletal remains identified as Homo floresiensis. Use-wear ... [more ▼]Chipped stone flakes from sedimentary deposits from the Liang Bua site, Flores, Indonesia have been found in association with faunal remains and skeletal remains identified as Homo floresiensis. Use-wear and well-preserved organic residues on these flakes provide an opportunity to understand subsistence and behaviour of Homo floresiensis by determining how they were manipulated and what they were used for. This paper describes the analytical techniques including various microscope and staining methodologies used in residue analyses. It compares the efficacy and describes the outcome of these techniques in relation to the functional analysis of the Liang Bua lithic assemblage. [less ▲]Detailed reference viewed: 49 (2 ULg) The effect of ageing and encoding instructions on episodic memoryHagelstein, Catherine ; François, Sarah ; Manard, Marine et alPoster (2015, May 28)During ageing, a decline in episodic memory is observed, characterized by decreased recollection (a). In this study, we investigated the influence of encoding instructions, intentional or incidental, on ... [more ▼]During ageing, a decline in episodic memory is observed, characterized by decreased recollection (a). In this study, we investigated the influence of encoding instructions, intentional or incidental, on the performance of younger and older adults during an episodic memory task. Twenty young volunteers (aged 18 to 30 years old) and 20 older volunteers (aged 61 to 72 years old) participated in this experiment. The stimuli consisted of 300 black-and-white drawings of common objects. The task comprised two steps. During the encoding phase, 100 items were presented once ("hard" condition) and 100 other items were presented twice ("easy" condition). During recognition, the items from the encoding phase were presented again, as well as 100 new items. In each age group, half of the participants received incidental encoding instructions (they had to make size judgements about the objects depicted) while the other half were explicitly asked to memorize the objects presented because they would be asked to recognize them later on (intentional encoding). During recognition, they performed a Remember-Know judgement for the items they believed they had seen earlier. We carried out ANOVAs in order to test for the influence of instructions, age group and number of repetitions of the items in one hand on the percentage of recollection and on the other hand on the percentage of familiarity (p<.05). Results show a significant effect of age, with more correct recollection responses in young adults, whereas more correct familiarity was found in older adults. Furthermore, it was found that the items presented twice lead to more recollection than those presented only once. Finally, these results also suggest that in the older group of participants, only for the items presented twice, intentional encoding instructions lead to more recollection and less familiarity. This finding is consistent with previous work showing that the elderly do not easily use elaborate encoding strategies, and that they need more support (here, a second exposition to the material) in order to perform a deep encoding when they are encouraged to do so with intentional learning instructions (b). (a) Bugaiska, A., Clarys, D., Jarry, C., Taconnat, L., Tapia, G., Vanneste, S., & Isingrini, M. (2007). The effect of aging in recollective experience: the processing speed and executive functioning hypothesis. Consciousness and Cognition, 16(4), 797-808. doi: 10.1016/j.concog.2006.11.007 (b) Froger, C., Bouazzaoui, B., Isingrini, M., & Taconnat, L. (2012). Study time allocation deficit of older adults: the role of environmental support at encoding? Psychology and Aging, 27(3), 577-588. doi:10.1037/a0026358 [less ▲]Detailed reference viewed: 37 (7 ULg) The impact of ageing on episodic memory encoding: an fMRI studyFrançois, Sarah ; Angel, Lucie; Salmon, Eric et alPoster (2015, May 28)It is now commonly accepted that a decline in episodic memory is observed with ageing: while recollection processes are impaired, familiarity seems to be relatively preserved (a). Older individuals appear ... [more ▼]It is now commonly accepted that a decline in episodic memory is observed with ageing: while recollection processes are impaired, familiarity seems to be relatively preserved (a). Older individuals appear to recruit prefrontal areas bilaterally when their encoding is successful, while in young adults this activation is found to be left-lateralized (b). In this study, we were interested in the differences between younger and older participant regarding cerebral activity during encoding depending on whether the item elicited recollection or familiarity during the recognition phase. Twenty young volunteers (aged 19 to 29 years old) and 19 older volunteers (aged 60 to 78 years old) were presented visual stimuli depicting objects. During a first fMRI session, they were asked to make a size judgement about them. Then, in a second phase, the subjects were shown the items previously encountered during the encoding phase, as well as distractors. Participants' task was to determine which one were new and which one were seen earlier. For the latter, they also performed a Remember-Know judgement. Data were analysed using SPM8, with an event design comparing modifications in cerebral activity between the two subjects groups during encoding (1) for the items leading to recollection during the recognition phase compared to those leading to familiarity, and (2) for the items associated with familiarity during the recognition phase compared to those which were not recognized. Results show that older adults display a heightened activity in the right middle frontal gyrus, medial cingulate and paracingulate left gyri as well as in the precuneus, bilaterally when they engage recollection processes. Given that activations in these areas did not correlate with performance, they could be interepreted either as dedifferentiation or as an attempt of the ageing brain to compensate for a less elaborate encoding. However, no increase of activity was associated with familiarity processes in older adults, possibly because they are less demanding regarding attentional resources. (a) Bugaiska, A., Clarys, D., Jarry, C., Taconnat, L., Tapia, G., Vanneste, S., & Isingrini, M. (2007). The effect of aging in recollective experience: the processing speed and executive functioning hypothesis. Consciousness and Cognition, 16(4), 797-808. doi: 10.1016/j.concog.2006.11.007 (b) Duverne, S., Motamedinia, S., & Rugg, M. D. (2009). The relationship between aging, performance, and the neural correlates of successful memory encoding. Cerebral Cortex, 19(3), 733-744. doi:10.1093/cercor/bhn122 [less ▲]Detailed reference viewed: 39 (6 ULg) Capillary electrophoretic analysis of intact virus-like particles of human papillomavirus (HPV-VLP)Bettonville, Virginie ; Nicol, Jérôme ; Thelen, Nicolas et alConference (2015, May 28)Detailed reference viewed: 19 (5 ULg) Stone tool hafting and use in the European Upper Palaeolithic: the first results of the analysis of Gravettian tools from Hohle FelsTaipale, Noora ; Rots, Veerle Conference (2015, May 28)European Upper Palaeolithic lithic assemblages have been so far defined largely on a typological or technological basis, while extensive studies that would utilise the full potential of microwear analysis ... [more ▼]European Upper Palaeolithic lithic assemblages have been so far defined largely on a typological or technological basis, while extensive studies that would utilise the full potential of microwear analysis have been few. This contribution presents the first results of an ongoing PhD project dedicated to the variability in stone tool use and hafting in the Upper Palaeolithic of Central and Western Europe. The aim of the project is to understand the development as well as regional patterns in tool hafting and use in the Gravettian and Magdalenian, and thus better explain the observed morphological and technological shifts. For this purpose, samples of tools from five European key sites with well-dated sequences (Hohle Fels, Geißenklösterle, Vogelherd, Maisières-Canal, and Abri Pataud) will be analysed giving a special emphasis on hafting traces. The study wishes to promote functional analysis as an integral part of technological studies, not as a mere side note. The German cave site Hohle Fels is used here as a case study to illustrate the potential of this kind of approach. The first results of the analysis of the site’s Gravettian material will be put into a wider context of earlier published results as well as preliminary observations made on the other assemblages included in the present study. Building on these results, the impact of tool hafting and use on the morphology of Gravettian lithic implements will be discussed. [less ▲]Detailed reference viewed: 35 (0 ULg) The neural bases of proactive and reactive control processes in healthy agingManard, Marine ; François, Sarah ; SALMON, Eric et alPoster (2015, May 28)Background. Research on cognitive control suggests an age-related decline in proactive control abilities (an anticipatory form of control) whereas reactive control (consecutive to conflict detection ... [more ▼]Background. Research on cognitive control suggests an age-related decline in proactive control abilities (an anticipatory form of control) whereas reactive control (consecutive to conflict detection) seems to remain intact [1]. As proactive and reactive control abilities were associated to specific brain networks [2], this study investigated age-related effects on the neural substrates associated to each kind of control. Method. A modified form of the Stroop task was administered to 16 young and 16 older adults in an event-related fMRI experiment. In this version of the Stroop task, three different contexts were created: (1) a mostly congruent context (MC, inducing reactive control) with a majority of congruent items, (2) a mostly incongruent context (MI, inducing proactive control) with mainly interfering items, (3) a neutral context (MN) with mainly neutral items. Preprocessing and statistical analyses were performed with SPM8 (p<.001 uncorrected). Results. Behavioral results (p<0.05) indicated faster processing of interferent items in the MI than MC context in young participants only. With regard to neuroimaging data, the comparison of the two groups showed that the processing of interferent items in the MI context is associated to decreased activity in (mainly right-sided) frontal and temporal areas in the older group. On the contrary, in the MC context, increased activity was observed in bilateral frontal areas for older compared to younger participants. Discussion. Behavioral results confirm that older participants have difficulties with the implementation of proactive control that is associated to decreased brain activity (compared to young participants) in areas underlying Stroop performance. However, the recruitment of supplementary frontal areas we observed in the reactive control condition suggests compensation processes. So, aging seems to differentially affect the neural networks associated to the various kinds of cognitive control. [less ▲]Detailed reference viewed: 37 (7 ULg) Influence of age and consumption level on explicit and implicit expectancies of alcohol related-stimulation and sedationVilenne, Aurélie ; Quertemont, Etienne Poster (2015, May 28)Detailed reference viewed: 8 (2 ULg) Work incapacity and chronic pain patients: Is there an impact of work incapacity on anxiety and depression?Beaumel, Alexia; Vanootighem, Valentine ; Gillet, Aline et alPoster (2015, May 28)In 2011, a report of the Federal Public Service have shown that 8.5% of the Belgian population suffers from chronic pains, which represents 938 300 belgian people (Berquin et al., 2011). These persistent ... [more ▼]In 2011, a report of the Federal Public Service have shown that 8.5% of the Belgian population suffers from chronic pains, which represents 938 300 belgian people (Berquin et al., 2011). These persistent pains may result in functional limitations on both domestic and professional domains which may lead to temporary or permanently work incapacity (Faymonville et al., 2014). These incapacities may in turn cause a social withdrawal and a tendency to focus on pain (Berquin et al., 2011). Additionally, patients are prone to emotional modifications due to persistent pain (Ossipov et al., 2010). All of these factors may contribute in the emergence of anxiety and depressive symptoms. The present study examines the impact of type of work incapacities (at work, temporary incapacity and permanent incapacity) on anxiety and depression scores as a function of diagnoses (fibromyalgia, chronic pain syndrome, back pain, polyalgia). 123 patients suffering from chronic pain completed a measure of anxiety and depression (HADS), and a self-reported questionnaire of psychological and physical disability at work. We did not found any significant effect of type of work incapacities on anxiety and depression scores. Results present tables of frequencies to illustrate the social and professional situations of patients as a function of chronic pain diagnoses. [less ▲]Detailed reference viewed: 48 (5 ULg) Environmental impact assessment of rail freight intermodalityMerchan Arribas, Angel ; Belboom, Sandra ; Léonard, Angélique in Rasouli, Soora; Timmermans, Harry (Eds.) Current issues in transportation research - Proceedings of the BIVEC/GIBET transport research days 2015 (2015, May 28)The European Commission’s White Paper on transport (European Commission, 2011) seeks to achieve an efficient and sustainable balance between the various transport modes. Environmental impact studies on ... [more ▼]The European Commission’s White Paper on transport (European Commission, 2011) seeks to achieve an efficient and sustainable balance between the various transport modes. Environmental impact studies on intermodality transport show that rail freight transport is the land-based transport that has a higher environmental performance compared to intermodal road-rail and all-road transport (Fries and Hellweg, 2014), especially when electrified railway is used (Spielmann and Scholz, 2005). Life Cycle Assessment (LCA) methodology allows us to model as best as possible the environmental impacts of several pollutants in numerous categories. For other categories such as accident damages, noise impact and land use, new developments have to be performed. For the environmental impact assessment, all life cycle phases of rail freight transport operation, rail infrastructure, and rail equipment are taken into account (Spielmann et al., 2007). [less ▲]Detailed reference viewed: 40 (4 ULg) Polyplex Based on Polycarbonate Polymers for an Efficient Delivery of HDAC5 and HDAC7 siRNAFrère, Antoine ; Evrard, Brigitte ; Mottet, Denis et alConference (2015, May 28)Detailed reference viewed: 19 (4 ULg) DEVELOPMENT OF LIPOPLEXES FOR A TOPICAL TREATMENT OF HPV16 INDUCED LESIONS: In vitro and ex vivo studiesLechanteur, Anna ; Furst, Tania ; Delvenne, Philippe et alConference (2015, May 28)Detailed reference viewed: 6 (0 ULg) Executive functions in normal aging: Impact of cognitive reserve and objective physical activityGilsoul, Jessica ; Simon, Jessica ; Collette, Fabienne Poster (2015, May 28)It is now acknowledged that there exists a large inter-individual variability in age-related cognitive changes. According to Stern (2009), the cognitive reserve built up throughout the life span will make ... [more ▼]It is now acknowledged that there exists a large inter-individual variability in age-related cognitive changes. According to Stern (2009), the cognitive reserve built up throughout the life span will make seniors more or less resilient to the deleterious effects of aging on cognition, with seniors having a high level of cognitive reserve being more prone to successfully cope with cognitive and neuronal changes. Currently, few studies have focused on the specific effects of different factors of cognitive reserve on cognition. Consequently, the objective of this study is to determine the impact of four determinants of cognitive reserve on executive functions in normal aging. Sixty-eight healthy participants aged 60 to 80 were enrolled. Regarding executive functions, Inhibition (Stroop test, Hayling test, TAP Incompatibility subtest), Shifting (TAP Flexibility subtest, Plus-Minus task), and Updating (Letter-Number Sequencing subtest from MEM III, Letter memory task, 2-back task) were assessed (Miyake et al., 2000). Cognitive reserve was measured by questionnaires assessing educational level, occupation, leisure activities and physical activity. Moreover, an accelerometer allowed quantitative measure of physical activity by recording body movements during two weeks. Group comparisons (p<0.05) showed that seniors with a high level of cognitive reserve (measured by a global composite z-score) have better updating abilities (Letter memory task and updating composite score). In order to test the influence of each cognitive reserve factor on executive functions, simple linear regressions (p<0.05) were performed. The results showed that the educational level accounts for a significant part of the variance in flexibility (TAP Flexibility) and updating (Letter-Number sequencing, 2-back and composite score). The occupational level accounts significantly for the variance of the updating composite score. Regarding the quantitative physical activity, the mean number of minutes per day in moderate or intense physical activity significantly predicted the updating composite score. These results indicate that the level of cognitive reserve is related to abilities in some executive tests, particularly updating abilities. Importantly, all aspects of cognitive reserve are not associated with the three executive processes. This indicates a specificity of the protective effect of cognitive reserve on executive abilities. [less ▲]Detailed reference viewed: 185 (5 ULg) Validation d'une méthode d'analyse quantitative de l'équol par UPLC®-MS/MS dans le lait de vache - Application aux laits commercialisés en Wallonie (Belgique)Daems, Frédéric ; Lognay, Georges ; Romne, Jean-Michel et alConference (2015, May 27)Dans le cadre d’un projet intitulé «PhytoHealth », une méthode d’analyse quantitative de l’équol dans le lait a été développée et validée selon les recommandations de l’EMA/CVMP/VICH/463202/2009. Celle-ci ... [more ▼]Dans le cadre d’un projet intitulé «PhytoHealth », une méthode d’analyse quantitative de l’équol dans le lait a été développée et validée selon les recommandations de l’EMA/CVMP/VICH/463202/2009. Celle-ci est constituée d’une étape d’hydrolyse enzymatique, suivie d’une double extraction liquide/liquide et d’une analyse par chromatographie liquide ultra performante couplé à un spectromètre de masse en tandem (UPLC®-MS/MS). Une fois les différents paramètres tels que la fiabilité, sensibilité et/ou robustesse de la méthode confirmées, celle-ci a permis, pour la première fois, d’estimer la teneur en équol d’ échantillons de laits commercialisés en Wallonie. Une Cinquantaine de laits ont été prélevés aléatoirement dans les commerces durant une période définie. Tous les échantillons possédaient une teneur en équol ≥ 10ng.mL-1. En comparant les valeurs moyennes, on a constaté qu’il n’y avait pas de différence entre les 4 catégories de laits analysés (entier, demi-écrémé, écrémé et cru). Par contre, une différence hautement significative a pu être observée entre les laits provenant de la filière biologique et ceux de la filière conventionnelle. Dans le premier cas, les teneurs varient entre 10 et 50 ng.mL-1 par contre, dans le second, elles varient entre 70 et 130 ng.mL-1. Cet impact de la filière biologique sur la teneur en équol dans les laits a pu être confronté à d’autres études européennes et confirmé. [less ▲]Detailed reference viewed: 41 (5 ULg) Exploring the secretome of bone marrow mesenchymal and neural crest-derived stem cells for treating spinal cord injuriesNeirinckx, Virginie ; Agirman, Gulistan; Coste, Cécile et alin Cytotherapy (2015, May 27)Detailed reference viewed: 22 (1 ULg) Dense-lineability in classes of ultradifferentiable functionsEsser, Céline Conference (2015, May 27)The Denjoy-Carleman classes are spaces of smooth functions which satisfy growth conditions on their derivatives defined through weight sequences. In this talk, given a Denjoy-Carleman class E of Beurling ... [more ▼]The Denjoy-Carleman classes are spaces of smooth functions which satisfy growth conditions on their derivatives defined through weight sequences. In this talk, given a Denjoy-Carleman class E of Beurling type that strictly contains another non-quasianalytic class F of Roumieu type, we handle the question of knowing how large the set of functions in E that are nowhere in the class $F$ is. In particular, we prove the dense-lineability of the set of functions of $E$ which are nowhere in F. Consequences for the Gevrey classes are also given. We extend then these results to the case of classes of ultradifferentiable functions defined imposing conditions on their Fourier Laplace transform using weight functions. [less ▲]Detailed reference viewed: 15 (3 ULg) Direct Numerical Simulation of Mixed Convection in Turbulent Channel Flow: On the Reynolds number dependency of momentum and heat transfer under unstable stratificationSid, Samir ; Dubief, Yves; Terrapon, Vincent Conference (2015, May 27)Direct numerical simulations of unstably stratified turbulent channel flow have been performed in order to investigate the Reynolds number effect on mixed convection. Six different cases are considered ... [more ▼]Direct numerical simulations of unstably stratified turbulent channel flow have been performed in order to investigate the Reynolds number effect on mixed convection. Six different cases are considered with friction Reynolds number Re_\tau =180 and 395 and friction Richardson number Ri_\tau = 0, 100 and 1000. It is shown that both friction coefficient and Nusselt number increase under unstable stratification for a sufficiently large Richardson number. At low Richardson number, the friction coefficient can either increase or decrease depending on the Reynolds number. The drag reduction is associated with an increase of mean velocity due to an enhanced dissipation of Reynolds shear stress by pressure strain in the buffer region. The breakdown of the Reynolds analogy is demonstrated as the turbulent Prandtl number exhibits a non-constant behavior due to buoyancy. [less ▲]Detailed reference viewed: 45 (5 ULg) Control of nuclear sample polarization using optical pumping and radio-frequency methodsLenaers, Florence ; Glover, Rohan ; Bastin, Thierry Conference (2015, May 27)Laser-cooled and trapped radioactive isotopes are now being used to probe the properties of the weak interaction in nuclear beta decay. In this context, it is essential that one be able to control the ... [more ▼]Laser-cooled and trapped radioactive isotopes are now being used to probe the properties of the weak interaction in nuclear beta decay. In this context, it is essential that one be able to control the nuclear polarization of the atomic samples. We present two polarization/depolarization schemes for argon-35, whose mirror transition to chlorine-35 is a particularly sensitive candidate for precision measurements in nuclear beta decay. [less ▲]Detailed reference viewed: 26 (4 ULg) Tel Quel, Change et Poétique en 1970 : "l'affaire de Lausanne"Lorent, Fanny Conference (2015, May 27)Detailed reference viewed: 12 (2 ULg) Application du plan d’expérience de Box-Behnken et de la méthodologie des surfaces de réponses pour optimiser une méthode de quantification de phyto-œstrogènes dans les fourragesDaems, Frédéric ; Lognay, Georges ; Romnee, Jean-Michel et alConference (2015, May 27)Dans le cadre d’un projet de valorisation des prairies, intitulé « PhytoHealth », une méthode d’analyse quantitative constituée d’une étape d’extraction à l’aide d’un bain à ultrasons, suivi d’une ... [more ▼]Dans le cadre d’un projet de valorisation des prairies, intitulé « PhytoHealth », une méthode d’analyse quantitative constituée d’une étape d’extraction à l’aide d’un bain à ultrasons, suivi d’une hydrolyse enzymatique et d’une analyse par UPLC®-MS/MS a été développée pour assurer le dosage de phyto-œstrogènes dans les fourrages. Pour alléger l’optimisation de la préparation des échantillons, la méthodologie des surfaces de réponses a été utilisée. Un plan d’expérience de Box-Behnken a été appliqué aux étapes d’extraction et d’hydrolyse. Parmi les différents facteurs pris en compte, les impacts de la nature du solvant utilisé lors de l’extraction ainsi que la température et le pH lors de l’hydrolyse, ont clairement pu être mis en évidence. L’ensemble des données générées a également permis de définir des conditions optimales d’extraction et d’hydrolyse pour chacun des composés. Ces conditions n’étant pas identiques pour chacun d’entre eux, un compromis a été trouvé afin de pouvoir analyser l’ensemble de ces composés simultanément. L’ensemble de la méthode a ensuite été validée selon les recommandations de l’EMA/CVMP/VICH/463202/2009, pour confirmer sa fiabilité et robustesse. Cette dernière, combinée au model d’ensilage en sacs sous vide, a permis pour la première fois de suivre la cinétique d’évolution de 4 phyto-œstrogènes (daidzéine, génistéine, formononétine et biochanin A) durant une période d’ensilage. [less ▲]Detailed reference viewed: 41 (3 ULg) Nature, éthique et philosophie. De quelques motifs goethéens dans la pensée de Wittgenstein.Zincq, Aurélien Conference (2015, May 27)Detailed reference viewed: 12 (1 ULg) Process-based method for groundwater resource vulnerability mapping with regards to solute contamination at the surfacePopescu, Cristina; Brouyère, Serge ; Orban, Philippe et alConference (2015, May 26)Numerous groundwater vulnerability methods have been developed taking into consideration a variable number of factors. The most common techniques are based on calculation of an index expressing the ... [more ▼]Numerous groundwater vulnerability methods have been developed taking into consideration a variable number of factors. The most common techniques are based on calculation of an index expressing the protective effect of underground formations overlying the groundwater resource. However, it has been shown that different overlay and index methods applied to the same system can yield dramatically dissimilar results (among others, Gogu et al., 2003). The limitation of most of these methods is related to their use of a qualitative definition of groundwater vulnerability, as opposed to a definition based on a quantitative description of contaminant migration. A process-based point of view is proposed and based on three factors describing a pollution event (Brouyère et al., 2001): (1) the transit time from the source to the target, (2) the duration of the contamination breakthrough at the target, (3) the ratio between the maximum concentration at the target to the released concentration at the contamination source. The assessment can then be based on the impulse response at the ‘target’ to a Dirac-type solicitation (point, unit mass, instantaneous source of pollution), considering only physical hydrodispersive processes for intrinsic vulnerability and both physical and biochemical processes for specific vulnerability. The breakthrough curve obtained after a vertical transfer through the overlying layers can be computed pixel by pixel. Automatically processing the columns with identical characteristics, 1D partially saturated flow and solute transport computations are performed. Different maps are obtained for the three above mentioned factors. On the basis of these results, different vulnerability maps can be built according to the weighting coefficients agreed by the local community or decision makers. This concept allows a clear distinction between conventional aspects and process-based results in the building of a final vulnerability indicator. This methodology has the further advantage to consider the possible impact of runoff conditions occurring at the land surface and possibly leading to lateral contamination of groundwater through downstream preferential infiltration features. To solve this problem, Popescu et al. (2004 & 2008) and Dassargues et al. (2009) proposed a method for quantifying a lateral “dangerosity” coefficient using runoff coefficients based on land use, slopes, and soil properties. A test application is illustrated on a case-study located in a limestone basin in Belgium. [less ▲]Detailed reference viewed: 17 (5 ULg) Sensitivity and vulnerability to groundwater overexploitation by a ‘pressure state impact’ and process based approachBeaujean, Jean; Lemieux, Jean-Michel; Therrien, René et alConference (2015, May 26)A methodology is developed for proposing a groundwater vulnerability assessment in a Pressure-State-Impact causal chain that is familiar to decision makers. The ‘Driver Pressure State Impact Response’ ... [more ▼]A methodology is developed for proposing a groundwater vulnerability assessment in a Pressure-State-Impact causal chain that is familiar to decision makers. The ‘Driver Pressure State Impact Response’ (DPSIR) framework, for describing interactions between society and the environment, defines a chain of Drivers that exert Pressures on the State of a given resource, such as groundwater, which then generates an Impact that will require an appropriate Response (Kristensen, 2004). The method is here based on the calculation of sensitivity coefficients for a user-defined groundwater state for which several physically-based indicators are proposed. These sensitivity coefficients reflect the easiness with which the groundwater state transmits pressures into impacts. They are grouped into a vulnerability matrix of pressures and impacts that quantify vulnerability for every combination of causal links identified in the DPSIR chain. For that reason, the sensitivity coefficients are converted to vulnerability, using the concept of ‘transgressing a given threshold’, which is commonly used in socioeconomic sciences (Luers et al. 2003). The concept of ‘rising above a given concentration threshold’ can be used for groundwater quality issues. The concept of ‘falling below a given piezometric head threshold’ can be used for groundwater quantity issues as aquifer overexploitation problems. Outside the careful selection of the sensitivity analysis method that can significantly influence the computational effort (Beaujean et al., 2013), emphasis is given to the illustration of the general methodology on a simple groundwater quantity case (of an alluvial aquifer with concerns related to water supply) demonstrating the potential use of this general and physically based vulnerability assessment method. While the methodology is general, the choice of causal chains has to be made prior to the calculation. The vulnerability is also related to a damaged state and is related to the ‘distance’ between the current state and a given threshold. This choice is arbitrary such that the vulnerability is sensitive to the choice of the threshold. [less ▲]Detailed reference viewed: 17 (0 ULg) Propagation of uncertainties in the modelling of MEMS resonators (using a 3-scale probabilistic approach)Lucas, Vincent ; Wu, Ling ; Golinval, Jean-Claude et alConference (2015, May 26)In order to ensure the accuracy of MEMS vibrometers, the first resonance frequency should be predicted at the design phase. However, this prediction is subjected to randomness: there is a scatter in the ... [more ▼]In order to ensure the accuracy of MEMS vibrometers, the first resonance frequency should be predicted at the design phase. However, this prediction is subjected to randomness: there is a scatter in the reached value resulting from the uncertainties involved in the manufacturing process. The purpose of this work is to take into account these uncertainties of the microstructure. The objective is a non-deterministic model that can be used since the design stage. The material is the source of uncertainties: the beam resonator is made of a polycrystalline material in which each grain has a random orientation. Solving the problem with a full direct numerical simulation combined to a Monte-Carlo method allows the probability density function of the resonance frequency to be computed. However this methodology is computationally expensive due to the number of degrees of freedom required to study one sample, motivating the development of a computationally efficient method. Towards this end a 3-scales stochastic model for predicting the resonance frequency of a micro-beam made of a polycrystalline linear anisotropic material is described. At the lower scale, we model the micro-structure with micro-volume elements. Due to the small-scale involved, the representativity of these micro-volume elements is not achieved and thus Statistical Volume Elements (SVE) are considered. These SVEs are generated under the form of a Voronoï tessellation, each grain being assigned a random orientation. Computational homogenization is applied over the SVEs, along with a Monte-Carlo procedure, to obtain a stochastic characterization of the elasticity tensor at the second scale of interest, the meso-scale. The spatial correlation between SVEs is also estimated. A generator based on spectral methods is implemented. Afterwards, using a stochastic finite element method, these meso-scale uncertainties are propagated by taking account of the spatial correlation up to the higher scale to predict the probabilistic behavior of the MEMS resonator. [less ▲]Detailed reference viewed: 19 (4 ULg) Outils logiques pour l’analyse des sensations. Théorie des ensembles et méréologieLeclercq, Bruno Conference (2015, May 26)Detailed reference viewed: 27 (0 ULg) Venus nightglow intensity and solar activity: any correlation?Soret, Lauriane ; Gérard, Jean-Claude Conference (2015, May 26)We examine if any correlation is observed between the brightness of the O2 nightside airglow and the EUV solar irradiance using the full database of VIRTIS IR images. We conclude that, as was the case for ... [more ▼]We examine if any correlation is observed between the brightness of the O2 nightside airglow and the EUV solar irradiance using the full database of VIRTIS IR images. We conclude that, as was the case for the NO airglow observed during the Pioneer Venus mission, no response to solar activity is observed. [less ▲]Detailed reference viewed: 17 (1 ULg) A stochastic multiscale analysis for MEMS stiction failureHoang Truong, Vinh ; Wu, Ling ; Golinval, Jean-Claude et alConference (2015, May 26)Stiction is a major failure in microelectromechanical system (MEMS) devices in which two contacting surfaces can remain stuck together because of the adhesive forces, such as van der Waals forces and ... [more ▼]Stiction is a major failure in microelectromechanical system (MEMS) devices in which two contacting surfaces can remain stuck together because of the adhesive forces, such as van der Waals forces and capillary forces. Stiction is a multiscale problem which is characterized by three different lengths: the MEMS device characteristic length, the roughness of the contacting surfaces, and the distance range of the adhesive forces. Because MEMS surfaces roughness and adhesive force distances are of comparable scales, the randomness in the contacting surfaces can result in important uncertainties on the interacting forces, and in turn lead to a scatter in the MEMS structural behavior. The purpose of this work is to quantify the uncertainties on the macro stiction behavior of a MEMS structure due to the randomness in its contacting surfaces. A full analysis, such as the combination of a Monte-Carlo simulation to generate random surfaces combined with finite element (FE) analyses to model the stiction behavior, is expensive in terms of the computational cost due to the difference in the scales between the macro characteristic length and the distance range of the adhesive forces. Thus, in this work, we develop a stochastic multiscale analysis. At the micro scale, the uncertainties in the interacting forces between two rough surfaces are investigated. The power spectral density function of the surface is characterized from experimental topology measurements, and interacting surfaces are then generated as Gaussian random surfaces. For each generated random surface, the interacting adhesive forces are calculated by using a modified Dejarguin-Muller-Toporov (DMT) model. The resulting adhesive contact forces can be integrated using the finite element method at the structural scale by associating to each discretized contacting point a sampled surface. We then use the Monte-Carlo method to quantify the uncertainties in the stiction behavior of the MEMS device. [less ▲]Detailed reference viewed: 41 (16 ULg) De la spécification à la création de nouvelles catégorisations sociales: Le cas de francophones vivant en Flandre et de néerlandophones vivant en WallonieDassargues, Alix Conference (2015, May 26)Nos recherches doctorales visent à étudier la manière dont des individus en situation d’allophonie « illégitime » se catégorisent socialement. Puisqu’aucune catégorie identitaire légitime (c.-à-d ... [more ▼]Nos recherches doctorales visent à étudier la manière dont des individus en situation d’allophonie « illégitime » se catégorisent socialement. Puisqu’aucune catégorie identitaire légitime (c.-à-d. institutionnalisée par les dictionnaires, les médias, les politiciens ou autres instances légitimatrices (Bourdieu 1982)) ne rend compte de la situation de francophones vivant en Flandre (région belge unilingue néerlandophone) et de néerlandophones vivant en Wallonie (région belge unilingue francophone excepté une petite communauté germanophone institutionnellement reconnue et territorialisée), ces individus conceptualisent le champ social de façon originale afin qu’il corresponde à leurs propres expériences de vie (Harder 2010 : 18). En se basant sur des principes tels que la légitimité d’un lexème dans l’espace discursif ou encore le caractère idiolectal ou non d’une catégorisation, nous nous proposons d’observer les modes de conceptualisation de l’identité par des locuteurs particulièrement aptes à formuler des catégorisations originales du champ social puisque leurs expériences de vie ne font pas l’objet de catégorisations légitimes. À partir de transcriptions d’entretiens semi-directifs, nous avons examiné le discours de témoins afin d’analyser leurs conceptualisations du champ social à travers les catégorisations qu’ils emploient. Nous prenons en compte les catégories légitimes et illégitimes citées dans les témoignages selon leur institutionnalisation (présence ou non dans les dictionnaires et dans les discours médiatiques) et la manière dont elles sont considérées par les locuteurs (catégorie considérée comme légitime ou non par les locuteurs). De la sorte, une typologie de nouvelles catégorisations identitaires a pu être établie sur la base d’une analyse linguistique : spécification d’un lexème légitime par une proposition relative , spécification d’un signifié par un redoublement de certains signifiants légitimes , spécification d’un signifié par l’instauration d’une gradation dans l’adéquation avec une catégorie légitime (stéréotype institutionnalisé) , modifications de signifiés dans des catégorisations légitimes , création de nouvelles catégorisations à partir d’adjectifs et de lexèmes légitimes , création de métaphores en transposant l’expérience d’un domaine conceptuel des catégories sociales (cf. Lakoff & Johnson 1980). Cette recherche interdisciplinaire suggère que la construction de sens s’établit à partir d’autres connaissances déjà organisées entre elles (Harder 2010:113) et partagées par une communauté d’individus. En choisissant le thème ambitieux de l’identification (ou la catégorisation) de soi et des autres, cette recherche permet également de transposer les connaissances de la linguistique cognitive au domaine social. Ainsi, elle confirme notamment que le modèle sémantique basé sur un prototype (Rosch 1978; Lakoff 1987) est adéquat pour rendre compte de la construction individuelle du sens dans le champ social. [less ▲]Detailed reference viewed: 16 (0 ULg) Gestion des déchets nucléaires en France et en Belgique: Quelle place pour la critique ?Parotte, Céline Conference (2015, May 25)Depuis les années 1970, avec la multiplication des controverses scientifiques (Callon, Lascoumes et Barthe 2001), souvent liées à des mouvements pacifistes en environnementalistes ; nous assistons à la ... [more ▼]Depuis les années 1970, avec la multiplication des controverses scientifiques (Callon, Lascoumes et Barthe 2001), souvent liées à des mouvements pacifistes en environnementalistes ; nous assistons à la naissance d’un flux d’incertitude et de critique politico-sociale, dirigée principalement vers le monde scientifique, sa production et ses hésitations. Il est malaisé de prévoir si cela mènera à une réelle désolidarisation des notions de science, technologie et progrès, mais il reste à supposer que cette critique permettra une gestion plus réflexive des effets majeurs du développement scientifique et technologique (Schot et Rip 2009). En d’autres termes, bien que les liens entre les idéologies du progrès et de la technologie restent très souvent puissants et non remis en question, on assiste au même moment à une critique sociale des conséquences sur le processus de gestion des choix technologiques qui s’y rapportent. Cette contribution propose de s’attarder sur le cas de la gouvernance socio technique de la gestion des déchets hautement radioactifs depuis le « tournant participatif » opéré dans les années 90 en France et en Belgique. Il s’agit de poser un regard critique sur l’apparition d’un nouveau mode de gouvernance plus participatif (au travers de l’inclusion de nouveaux acteurs) et ses conséquences. Dans quelle mesure ceux-ci redéfinissent-ils les positionnements du monde scientifique au sein du processus décisionnel ? Comment le monde scientifique reçoit-il les critiques qui lui sont adressées ? Plutôt que des tendances globales, cette contestation témoigne le plus souvent d’une mosaïque d’activités critiques dynamiques, concurrentes ou complémentaires dont les effets semblent faire vaciller — ou à tout le moins mettre sous tension — l’organisation, les routines et les institutions des sociétés modernes (Delvenne 2011). Cette mosaïque reflète le dynamisme des acteurs sociaux qui propagent leurs agendas et défendent leurs intérêts à travers la négociation de concessions, l’enchevêtrement de décisions et la cristallisation de rapports de force. En d’autres termes, les avancées d’un projet comme la gestion des déchets nucléaires ne sont pas la progression inéluctable d’un processus uniformément accepté par toutes les tendances de la société. En réalité, il existe une multitude d’acteurs qui influencent sans cesse la nature de ses contours. Ces acteurs sociaux bénéficient d’espaces politiques et institutionnels divers pour exprimer leurs préférences et tenter de transformer durablement les critiques qu’ils formulent en actions politiques qui trouvent un écho plus large au sein de la société. [less ▲]Detailed reference viewed: 32 (4 ULg) About the Regularity of Cantor's BijectionSimons, Laurent ; Nicolay, Samuel Conference (2015, May 25)In 1878, Cantor proved that there exists a one-to-one correspondence between the points of the unit line segment [0,1] and the points of the unit square [0,1]². Since this application is defined via ... [more ▼]In 1878, Cantor proved that there exists a one-to-one correspondence between the points of the unit line segment [0,1] and the points of the unit square [0,1]². Since this application is defined via continued fractions, it is very hard to have any intuition about its smoothness. In this talk, we explore the regularity and the fractal nature of Cantor's bijection, using some notions concerning the metric theory and the ergodic theory of continued fractions. This talk is based on a joint work with S. Nicolay. [less ▲]Detailed reference viewed: 13 (0 ULg) Charles Juliet : Du portrait a-posteriori à l’écriture de soi L’adresse à la mère comme tentative de désenfouissement dans LambeauxVandormael, Thomas Conference (2015, May 25)Lambeaux propose un diptyque de portraits. Dans la première partie, celui de la mère biologique. Dans la seconde, celui de l’auteur lui-même et au sein de celui-ci, enfin, le portrait de la mère adoptive ... [more ▼]Lambeaux propose un diptyque de portraits. Dans la première partie, celui de la mère biologique. Dans la seconde, celui de l’auteur lui-même et au sein de celui-ci, enfin, le portrait de la mère adoptive. La dimension vocative explicite de la narration en constitue à la fois l’originalité et le paradoxe. Le recours au « Tu » dans l’ensemble du texte fait advenir une poétique de l’adresse en laquelle se cristallise la spécificité du récit de filiation propre à l’autofiction de la littérature contemporaine : différent du simple devoir de mémoire ou encore de la - très en vogue - commémoration, il se situe plutôt du côté de la restitution, à laquelle il y a deux sens à donner : à la fois reconstituer ce qui fut et s’est défait, et rendre leur existence à ceux qui s’en sont trouvés dépouillés en faisant apparaître ce qui demeure enfoui et dont on n’a pu hériter. Pour répondre au silence d’une mère qu’il n’a pas connue et qui elle-même n’a pas pu s’exprimer, faute d’accès au langage ou d’une présence pour l’écouter, Juliet choisit l’instantané et l’immédiateté d’un discours d’interpellation au présent et la forme du dialogue avec les morts, forcément toujours en partie déjà voué à l’échec. Dès lors, notre propos souhaite interroger comment le choix du vocatif permet un dédoublement fécond du sujet,faisant advenir une relation de soi à soi qui déjoue les processus classiques de l'autobiographie.﻿﻿ [less ▲]Detailed reference viewed: 33 (1 ULg) Electric current crowding in nanostructured conductorsSilhanek, Alejandro Conference (2015, May 24)When current stream lines are forced to depart from their rectilinear trajectory due to the presence of an obstacle, they conglomerate at the sharp bends encountered on their paths. The consequent current ... [more ▼]When current stream lines are forced to depart from their rectilinear trajectory due to the presence of an obstacle, they conglomerate at the sharp bends encountered on their paths. The consequent current crowding is present in normal metals as well as in superconductors and has been, since long ago, identified as a key player in electromigration phenomena leading to failure in integrated circuit interconnects while might also be at the origin of local ablation in planar plasmonic structures. More recently, current crowding has been recognized as an important factor limiting the performance of superconducting single-photon detectors, leading to flux quanta motion rectification, or being a source of unwanted ratchet signal and depletion of surface barriers for magnetic flux penetration. In this talk, we will also show that in nanostructured superconductors at low temperatures, current crowding can trigger abrupt flux avalanches developing well defined geometrical patterns. Our experimental findings are backed up to the finest details, by simulations based on a phenomenological thermomagnetic model which, in turn, can be used to predict such complex structures and, given its reliability, allows one to estimate physical variables of more difficult experimental access, such as the local values of temperature and electric field. [less ▲]Detailed reference viewed: 33 (3 ULg) Immersie-onderwijs met het Nederlands als doeltaal: Onderzoek naar de attitudes en motivatie van de ouders van immersie- en niet-immersie-leerlingen uit Luikse secundaire scholende Le Vingne, Charlotte Conference (2015, May 23)Detailed reference viewed: 26 (3 ULg) La pneumoconiose des ouvriers mineurs : quelles connaissances pour quelles actions (c. 1860 – c. 1960)Geerkens, Eric Conference (2015, May 23)Detailed reference viewed: 15 (0 ULg) Gene-based replication strategy and meta-analysis in the context of epistasis: application for Alzheimer’s disease.Gusareva, Elena ; van der Lee, Sven; Katsumata, Yuriko et alPoster (2015, May 22)Although the discovery of biological epistasis via statistical methods remains a big challenge, large-scale epistasis studies have become more and more popular nowadays. Considering the power of genome ... [more ▼]Although the discovery of biological epistasis via statistical methods remains a big challenge, large-scale epistasis studies have become more and more popular nowadays. Considering the power of genome-wide association interaction analysis (GWAI) is conceptually lower when comparing to GWA using the same data, the genome-wide screenings for epistasis often ends with no statistically significant findings. Therefore, sound meta-analytic methodologies for combining evidence across independent gene-gene interaction studies, taking into account characteristics of individual studies, as well as protocols for good standard practice of meta-GWAI analysis are missing so far. The existing methodologies, whereas is suboptimal, may still be the first choice in meta-GWAI. In our study, the genome-wide significant interaction between two var¬¬iants of WWC1 and TLN2 genes were first discovered in males of EADI1 of Alzheimer’s disease (AD) case/control cohort. Adopting the gene-based replication approach recently advocated by Gusareva and Van Steen (Hum Genet 2014), we assessed association between all available variants from the pair of genes to test for pair-wise interactions in three independent AD replication cohorts (GERAD1, AD cohort from Rotterdam study - RS, and ADGC). Particularly, we used regression modeling with co-dominant coding of genetic markers (the one that was found to be the most powerful to identify epistasis and gives the least false positive results) and taking into account possible confounding factors (age and the first four PCs). We further meta-analyzed p-values for the interaction effects across all pairs of markers in males and females using Fisher summary test statistic. For the most interesting epistasis signal that occur in males of EADI1 cohort and two replication cohorts (RS and ADGC), we also conducted multi-locus genotype (MLG) association analysis (quantifies effects sizes of each of eight multilocus genotypes derived from the SNPs-pair versus the reference category - homozygous for the major alleles) and then met-analyzed results using the random effect or fixed effect models depending on presence of heterogeneity between studies. Adopting this approach we statistically replicated the interaction between WWC1 and TLN2 genes. Although, the biological validation of this finding is still ahead, we can already demonstrate effectiveness of the adopted meta-analysis pipeline to identify novel genetic factors potentially predisposing to AD. [less ▲]Detailed reference viewed: 27 (2 ULg) Modulatory effects of Ruthenium (II)-based complexes on oxidative stress induced by activated HL60 cells and NeutrophilsMouithys-Mickalad, Ange ; Collienne, Simon ; Franck, Thierry et alConference (2015, May 22)There is a growing interest on the use of metal-based chemotherapeutic agents to fight different types of cancers [1]. The most used family of the organometallic compounds is platinum derivatives whose ... [more ▼]There is a growing interest on the use of metal-based chemotherapeutic agents to fight different types of cancers [1]. The most used family of the organometallic compounds is platinum derivatives whose Cisplatin (CisPt) is the lead compound used for the treatment of various cancers including lung, testis, gastric, breast, etc. Nevertheless, beside its recognized therapeutic effects, side effects such as gastric toxicity and acute kidney failure were observed during the treatment, limiting its clinical use. Other compounds are currently studied and among them, Ruthenium (Ru) complexes have gained more importance for their less toxicity and lower aggressive effect on healthy tissues than CisPt. Ru-complexes are also more resorbed and excreted [2]. Numerous studies focused on the mechanisms of action of Ruthenium compounds to fight cancer, including antioxidant or pro-oxidant activity. During inflammation, activation and infiltration of neutrophils contribute to oxidant stress playing a crucial role in tumor development. Likewise, the degranulation of neutrophil causes the release of myeloperoxidase (MPO) which reacts with H2O2 to catalyze redox reactions. A therapeutic target to control inflammation is the modulation of oxidant enzymes and cells involved in radical species production and redox reactions. Because Ruthenium compounds can easily enter into cancer cells, a series of Ru(II)-complexes newly synthesized were used for this purpose. They were first tested for their radical scavenging activities using ABTS and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays. Amongst them, compound 1 (LD0436) and compound 2 (LD04037) were then studied for their ability to modulate the reactive oxygen species (ROS) production by inflammatory cells like human promyelocytic leukemia cell line (HL 60) and neutrophils (PMN) using fluorescence, chemiluminescence (CL) and electron spin resonance ESR techniques. The toxicity of those Ru-complexes against HL-60 and neutrophils was checked using Trypan blue exclusion assay. Altogether, CL and ESR findings indicate that both complexes 1 (LD0436) and 2 (LD0437) exhibit a dose-dependent inhibitory activity compared to CisPt, gallic acid, curcumin and quercetin, which were taken as reference molecules in the different systems investigated. Similarly, the tested complexes also display an antioxidant profile on the substrate oxidation catalyzed by peroxidase such as MPO mainly involved in acute and chronic inflammatory situations. 1: (RuCl(p-Cymen)(S2C.IDip)]+(PF6)-], 2: (RuCl(p-Cymen)(S2C.Icy)]+(PF6)-] References: 1. Ceresa C, Brawin A, Cavaletti G, Trinidad A et al., (2014) Current Medicinal Chemistry 20(21), 2237-2265. 2. Liu, Y, Zhang X, Zhang R, et al., (2011) European Journal of Inorganic Chemistry. 1974-1980. [less ▲]Detailed reference viewed: 41 (6 ULg) Assessing the consistency of ventilation in ocean biogeochemical models: oxygen solubility tracerMouchet, Anne Conference (2015, May 22)Detailed reference viewed: 15 (0 ULg) Electron paramagnetic resonance and fluorescence studies on potential anticancer properties of two new Ru(II) complexes : preliminary resultsCollienne, Simon ; Terrak, Mohammed ; Mouithys-Mickalad, Ange et alPoster (2015, May 22)Fight against cancer is a priority of today’s research. Since the discovery of the anticancer properties of cisplatin (CisPt) in 1965 by Rosenberg [1], the treatment of cancer by chemotherapy has known ... [more ▼]Fight against cancer is a priority of today’s research. Since the discovery of the anticancer properties of cisplatin (CisPt) in 1965 by Rosenberg [1], the treatment of cancer by chemotherapy has known great improvements. Unfortunately, CisPt has several side effects and is not effective against all kinds of cancer. Nevertheless its use highlights the great potential of organometallic compounds in the treatment of cancer [2]. Here we investigated the potential anticancer properties of two new organometallic compounds based on ruthenium II : [RuCl(p-cymene)(S2C.IDip)]+(PF6)- and [RuCl(p-cymene)(S2C.ICy)]+(PF6)-, named as LDO436 and LDO437 respectively. [less ▲]Detailed reference viewed: 51 (10 ULg) Alain Robbe-Grillet face à l'entretien journalistique : paradoxesLorent, Fanny Conference (2015, May 22)Detailed reference viewed: 14 (3 ULg) Make the ureter your friendBonnet, Pierre Conference (2015, May 22)Detailed reference viewed: 15 (1 ULg)