References of "Scientific congresses and symposiums"
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See detailNew insights into the microbiome of apple fruit surface “cv Pinova” through metagenomics
Dario, Angeli; Massart, Sébastien ULiege; Sare, Abdoul Razack ULiege et al

Conference (2017, June)

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See detailDiversity and biogeography of microorganisms in microbial mats of Antarctic lakes
Durieu, Benoit ULiege; Lara, Yannick ULiege; Obbels, Dagmar et al

in Van de Putte, Anton (Ed.) Book of abstracts: XIIth SCAR Biology Symposium, Leuven, Belgium, 10-14 July 2017. (2017, June)

The BelSPO project CCAMBIO aims to study the biogeographical distribution of microorganisms (bacteria, cyanobacteria, microeukaryotes) in lacustrine microbial mats using a combination of techniques ... [more ▼]

The BelSPO project CCAMBIO aims to study the biogeographical distribution of microorganisms (bacteria, cyanobacteria, microeukaryotes) in lacustrine microbial mats using a combination of techniques including microscopic observations, strain isolation and genetic characterisation, and molecular diversity assessments using Next Generation Sequencing of environmental DNA. The samples were collected in different Antarctic and sub-Antarctic biogeographical regions. [less ▲]

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See detailMicroplastics found in the stomach contents of Squalius cephalus from the Seine River
Collard, France ULiege; Gilbert, Bernard ULiege; Eppe, Gauthier ULiege et al

Poster (2017, June)

Microplastics (plastics < 5 mm) are emerging pollutants of growing concern. Since the 2000s their abundance, degradation and impacts on wildlife are more and more studied and understood. However, few data ... [more ▼]

Microplastics (plastics < 5 mm) are emerging pollutants of growing concern. Since the 2000s their abundance, degradation and impacts on wildlife are more and more studied and understood. However, few data are available particularly in freshwater ecosystems. Some fish species have plastic in their stomach contents such as: Gobio gobio, Alburnus alburnus, Leuciscus leuciscus while other species have not. In controlled conditions, microplastics were found to cause negative impacts in fish: leaching of micropollutants, endocrine disruption, hatching inhibition and decrease of growth rate of larvae. The first step in the understanding of these impacts is the quantification and the characterisation of ingested plastics by organisms in the field. Plastics and other anthropogenic particles (textile fibres) were isolated from 40 stomachs of Squalius cephalus (the European chub) collected in the Seine River (Paris) in August 2016. One station is upstream and the three others are downstream of the Paris Megacity conurbation. This megacity exerts a great pressure on the Seine River. Plastics were isolated thanks to a method using sodium hypochlorite and all particles were then analysed by Raman spectroscopy. The method consists in a degradation overnight of the organic matter in the stomach contents by sodium hypochlorite. This mixture is then filtrated and particles longer than 5 µm are resuspended into an ethanol (99%) solution for centrifugation. The precipitate, containing all particles denser than ethanol, is collected (1.3 ml) and spread on a mount for Raman spectroscopy. Several lasers were used, depending on the particle’s colour. Spectra were recorded with an accumulation ranging from 5 to 50s. Preliminary results showed that 7 individuals out of 25 already analysed (28%) had ingested at least one anthropogenic particle (AP). Eight APs were found and characterized, the majority of them (7) being dyed fibres. One of these fibres was made of a plastic polymer, the polyethylene terephthalate. The others were made of an undetermined material as Raman analyses gave only information on the dye. The eighth particle was a fragment of polypropylene. It is the first time that fish are studied as a part of plastic pollution in the Seine River. All isolated particles have been analysed leading to precise results. The percentage of occurrence is in the common range of other studies while much lower than the European flounder coming from the River Thames and higher than fish coming from Geneva Lake. It is not surprising that the majority of APs were fibres as another study in the river Seine found that the fibres concentration in water is far greater than the fragments concentration, as well as in urban runoff. It is also possible that the retention time of fibres in the gut is longer than fragments. Toxicological impacts of fibre ingestion is still unknown despite their ubiquity in many freshwater environments. [less ▲]

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See detailGelfand duality for compact pospaces
De Rudder, Laurent ULiege

Conference (2017, June)

It is well known that the category of compact Hausdorff spaces is dually equivalent to the category of commutative C^\star-algebras. More generally, this duality can be seen as a part of a square of ... [more ▼]

It is well known that the category of compact Hausdorff spaces is dually equivalent to the category of commutative C^\star-algebras. More generally, this duality can be seen as a part of a square of dualities between compact Hausdorff spaces, C^\star-algebras, compact regular frames and de Vries algebras. Three of these dualities have been extended to dualities between compact pospaces, stably compact frames and proximity frames, the fourth part of the square being lacking. We propose the category of bounded Archimedean l-semi-algebra to complete what will be the outside square of dualities and to extend to category of C^\star-algebras. [less ▲]

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See detailNet neutrality: Paid prioritization vs Zero-rating
Gautier, Axel ULiege

Conference (2017, June)

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See detailNumerical simulations of a non-charring ablator in high enthalpy flows by means of a unified flow-material solver
Schrooyen, Pierre; Coheur, Joffrey ULiege; Turchi, Alessandro et al

in 47th AIAA Thermophysics Conference : AIAA Aviation Forum, 5-9 June, Denver, CO (2017, June)

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See detailAutomatic phase identification of smart meter measurement data
Olivier, Frédéric ULiege; Ernst, Damien ULiege; Fonteneau, Raphaël ULiege

in Proc. of CIRED 2017 (2017, June)

This paper highlights the importance of the knowledge of the phase identification for the different measurement points inside a low-voltage distribution network. Besides considering existing solutions, we ... [more ▼]

This paper highlights the importance of the knowledge of the phase identification for the different measurement points inside a low-voltage distribution network. Besides considering existing solutions, we propose a novel method for identifying the phases of the measurement devices, based exclusively on voltage measurement correlation. It relies on graph theory and the notion of maximum spanning tree. It has been tested on a real Belgian LV network, first with simulated unbalanced voltage for which it managed to correctly identify the phases of all measurement points, second, on preliminary data from a real measurement campaign for which it shows encouraging results. [less ▲]

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See detailUnravelling the secret of the resistance of desert strains of Chroococcidiopsis to desiccation and radiation
Billi, Daniela; Fagliarone; Verseux, Cyprien et al

in Van de Putte, Anton (Ed.) Book of abstracts: XIIth SCAR Biology Symposium, Leuven, Belgium, 10-14 July 2017. (2017, June)

Chroococcidiopsis is a unicellular cyanobacterial genus that is growing in extreme dry conditions, either in low or high temperatures. At the lower end of the spectrum, they live as cryptoendoliths in ... [more ▼]

Chroococcidiopsis is a unicellular cyanobacterial genus that is growing in extreme dry conditions, either in low or high temperatures. At the lower end of the spectrum, they live as cryptoendoliths in rocks of the Mc Murdo Dry Valleys in Antarctica where they were discovered by Imre Friedmann, while at the higher end, they grow as hypoliths/endoliths in hot deserts, e.g. Negev, Gobi, Atacama. The capacity of desert strains of Chroococcidiopsis to stabilize their sub-cellular organization is so efficient that, when dried, they can cope with simulated space and Martian conditionsas well as with high doses of ionizing and UV radiations . [less ▲]

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See detailNondestructive inspection of aerospace composites by a fiber-coupled laser ultrasonics system
Vandenrijt, Jean-François ULiege; Languy, Fabian ULiege; Thizy, Cédric ULiege et al

in Proceedings of SPIE (2017, June)

Laser ultrasonics is a technique currently studied for nondestructive inspection of aerospace composite structures based on carbon fibers. It combines a pulsed laser impacting the surface generates an ... [more ▼]

Laser ultrasonics is a technique currently studied for nondestructive inspection of aerospace composite structures based on carbon fibers. It combines a pulsed laser impacting the surface generates an ultrasound inside the material, through the nondestructive thermoelastic effect. Second a detection interferometer probes the impacted point in order to measure the displacement of the surface resulting from the emitted ultrasound wave and the echo coming back from the different interfaces of the structure. Laser ultrasonics is of interest for inspecting complex shaped composites. We have studied the possibility of using frequency doubled YAG laser for the generation and which is fiber-coupled, together with a fiber-coupled interferometric probe using a YAG laser in the NIR. Our final system is a lightweight probe attached to a robot arm and which is able to scan complex shapes. The performances of the system are compared for different wavelengths of generations. Also we have studied some experimental parameters of interest such as tolerance to angle and focus distance, and different geometries of generation beams. We show some examples of inspection of reference parts with known defects. In particular C-scans of curved composites structures are presented. [less ▲]

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See detailVoltage Profile Correction in Distribution Grids Combining Single- and Two-level Controllers
Soleimani Bidgoli, Hamid ULiege; Van Cutsem, Thierry ULiege

in IEEE PES 2017 PowerTech conference proceedings (2017, June)

A real-time control scheme is proposed to correct undesired voltages in distribution networks by adjusting the reactive powers produced by Dispersed Generation Units (DGUs). This is performed at two ... [more ▼]

A real-time control scheme is proposed to correct undesired voltages in distribution networks by adjusting the reactive powers produced by Dispersed Generation Units (DGUs). This is performed at two levels: locally, in DGU controllers, and centrally by a supervisory controller acting on some of the DGUs only. The centralized, discrete controller solves a multi-time-step constrained optimization inspired of Model Predictive Control. Unacceptable voltage deviations are partially but rapidly corrected by the local controls. Further but slower corrections are applied by the upper level, taking advantage of the coordination between DGUs. This hybrid control is of practical interest where the deployment of the upper level control is not feasible or affordable over all DGUs. The proposed method effectiveness is demonstrated on a 75-bus test system. [less ▲]

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See detailGene Entity Recognition of Full Text Articles
Noll, Manuel ULiege; Lété, Jonathan ULiege; Meyer, Patrick ULiege

in ICBBS '17 Proceedings of the 6th International Conference on Bioinformatics and Biomedical Science (2017, June)

Biomedical scientific literature is an unexploited treasure. Due to the staggering number of publications it is literally intractable to gather manually all information. Automatized information extraction ... [more ▼]

Biomedical scientific literature is an unexploited treasure. Due to the staggering number of publications it is literally intractable to gather manually all information. Automatized information extraction (IE) is therefore key. An important subtask is the recognition of names in the text as specific entities ( named entity recognition, NER). NER for genes in biomedical literature is a challenging task. This paper reports preliminary results for the identification of gene names in full text with the naive Bayes, support vector machine and the random forest algorithm, showing that there is no loss on performance compared to the gene NER restricted to abstracts. [less ▲]

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See detailImpact of 3’-­‐sialyllactose and Bifidobacterium crudilactis on infant feces microbial composition and virulence modulation of Escherichia coli O157:H7, using the SHIME® gastrointes6nal model
Bondue, Pauline ULiege; Lebrun, Sarah ULiege; Crevecoeur, Sébastien ULiege et al

Poster (2017, June)

Bifidobacterium crudilactis, a bacterial species from bovine origin, growths on bovine milk oligosaccharides (BMO). Cell free spent media (CFSM) from B. crudilactis and 3’-sialyllactose (3’SL), a major ... [more ▼]

Bifidobacterium crudilactis, a bacterial species from bovine origin, growths on bovine milk oligosaccharides (BMO). Cell free spent media (CFSM) from B. crudilactis and 3’-sialyllactose (3’SL), a major BMO, modulated Escherichia coli O157:H7 virulence gene expressiona. In this study, the SHIME® gastrointestinal model was inoculated with 4 different treatments: 3’SL (ttm1), B. crudilactis (ttm2), 3’SL and B. crudilactis (ttm3) and CFSM from 3’SL and B. crudilactis culture (ttm4). In each section of the colon, samples were collected and analysed for short chain fatty acid (SCFA) concentration using HPLC, microbial populations using 16S rDNA metagenetic analysis and correlated with E. coli O157:H7 virulence gene expression. The results showed that SCFA levels were stable during the experiments. Metagenetic analysis showed a microbial diversity in transverse (TC) and descending colon (DC) close to feces, dominated by Bacteroides, Prevotella and Fusobacterium, while the ascending colon (AC) showed a different microbial diversity dominated by Veillonella. Ttm4 and ttm2 induced mainly a down-regulation of virulence genes: fliC in DC with ttm4, and luxS, stx1, qseA in AC, DC or TC with ttm2. Ttm1 also showed a down-regulation of fliC in DC, similar to the one observed with ttm4, but this was associated with an up-regulation of fliC and stx1 in AC or TC. Finally, ttm3 showed slight upregulation of ler, fliC and qseA in AC. These results show that ttm4 and ttm2 might have a positive effect against virulence expression of E. coli O157:H7. However, this trend has to be validated with the further replicates on the SHIME® system. [less ▲]

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See detailLeibniz and the Polyp, or the Metaphysical Puzzle of Life
Dony, Arthur ULiege

in Scienza e Philosophia (2017, June), 17

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See detailEmpathie et culpabilité : les émotions au coeur du lien social
Devillers, Bérengère ULiege

in Actes des 17èmes journées de valorisation de la recherche « La place des émotions dans le travail socio-éducatif » (2017, June)

Bonjour à tous, et merci aux organisateurs de m’avoir invitée. C’est un plaisir pour moi d’être là aujourd’hui parmi vous. Je vais tout d’abord revenir sur la traduction du « Good Lives Model ». Plusieurs ... [more ▼]

Bonjour à tous, et merci aux organisateurs de m’avoir invitée. C’est un plaisir pour moi d’être là aujourd’hui parmi vous. Je vais tout d’abord revenir sur la traduction du « Good Lives Model ». Plusieurs traductions sont communément admises, les plus connues étant celles de « modèle de bonne vie » ou « modèle de vie satisfaisante » ou encore « modèle de vies saines ». Il faut savoir que le groupe Antigone, dans lequel je travaille, n’adhère pas vraiment à ces définitions. En effet, nous trouvons que les traductions françaises proposées enferment le sujet dans une vision prescriptive de ce que devraient être les besoins, qu’elles laissent entendre qu’il y aurait des besoins universels auxquels tous les individus devraient répondre. Or nous ne nous y retrouvons pas et cela ne correspond pas à l’intention de Ward qui veut faire référence à une manière de vivre qui est bénéfique pour le sujet lui-même. Je vous propose donc de garder l’appellation anglophone, « Good Lives Model ». Je vais revenir à l’émergence de ce modèle : il s’agit d’un modèle de réhabilitation qui a vu le jour au début des années 2000 sous l’impulsion de Tony Ward, tout d’abord pour le public des auteurs d’infractions à caractère sexuel. Cependant, il s’est rapidement étendu à d’autres populations, notamment les auteurs de violences domestiques, le public psychiatrique, et ce pour le public aussi bien adolescent qu’adulte. D’autres adaptations ont depuis vu le jour, notamment à l’initiative d’un service français, l’ARCA, qui est spécialisé en recherche et en intervention en délinquance sexuelle, et où le directeur, Erwan Dieu, a adapté le Good Lives Model au public radicalisé. Plusieurs expériences ont également été menées en Belgique, notamment une à l’hôpital des Marronniers, à Tournai, dans une unité de défense sociale qui accueille des délinquants sexuels. L’équipe a décidé, suite à une formation, de reprendre les outils du Good Lives Model et de les adapter avec les patients, afin qu’ils correspondent à leur langage, à leur niveau de compréhension et donc à leurs besoins. Le GLM se veut avant tout humaniste, positiviste et tout à fait écologiste, parce qu’il tient compte des différents systèmes qui gravitent autour de la personne. Il a pour première cible de traitement le développement des besoins humains fondamentaux. Sa deuxième cible est la réduction du risque de récidive, mais qui se veut être un effet de la poursuite du bien-être et des besoins des personnes. Le Good Lives Model comprend des principes théoriques et des implications cliniques. Selon un principe prioritaire au niveau théorique, nous considérons que le délinquant est animé par les mêmes besoins humains que tout un chacun, mais que les voies qu’il emprunte ne sont pas pro-sociales. Nous mettrons donc la notion de besoin au centre de la prise en charge, bien plus que le passage à l’acte délinquant. Le principe clinique qui me paraît être le plus en lien avec le thème qui nous occupe aujourd’hui est peut-être la notion de responsabilité à substituer à celle de culpabilité. Je ne connais pas précisément votre cadre légal protectionnel de la jeunesse. En Belgique, dans les mesures qui sont privilégiées par le magistrat de la jeunesse dès lors qu’un jeune a commis un fait qualifié d’infraction, nous retrouvons les mesures réparatrices, mais dans une visée de responsabilisation du jeune, de prise en compte des conséquences dommageables pour les victimes. Tel est le mandat qui est confié aux équipes chargées du suivi du jeune. Dans le cadre de la philosophie du modèle GLM, nous verrons s’opérer un glissement de la notion de responsabilité, qui reposait avant tout sur les épaules du jeune, vers celles de l’intervenant psychosocial et de son environnement proche : les familiers, mais aussi tous les intervenants gravitant autour du jeune. Par quoi cela passe-t-il concrètement ? Tout d’abord le GLM est attentif à la définition du problème. Bien souvent, le problème est libellé soit dans les rapports qui ont été rédigés par au sujet du jeune, soit dans l’ordonnance qui précise notamment la qualification des faits. Nous laisserons cela de côté, et nous repartirons avec le jeune de la définition du problème tel qu’elle se pose pour lui, dans l’ici et maintenant. Nous ne repartirons donc pas du passé, mais nous nous centrerons sur les conséquences pour lui et pour son environnement dans le présent, ce qui suppose que nous devrons nous accorder sur les buts et objectifs de la prise en charge. Le jeune et les intervenants seront donc associés aux différentes phases du plan de traitement, où les intervenants psychosociaux auront également une responsabilité. Par conséquent, ils s’engageront à réaliser des démarches avec le jeune. Par quoi passe encore cette responsabilité ? L’intervenant psychosocial devra créer les conditions propices à un engagement et à un maintien du jeune dans la prise en charge. La notion de disposition au traitement (Treatment Readiness, Ward et al., 2004) nous éclaire ici sur cette question de l’engagement tant de l’usager que de l’intervenant dans le processus de changement. En effet, la disposition au traitement est définie comme étant « la présence de caractéristiques (états et dispositions) dans le chef du délinquant mais aussi de la situation thérapeutique qui sont susceptibles de promouvoir l’engagement dans la thérapie et donc l’amélioration des aptitudes au changement thérapeutique » (Ward et al., 2004). Il existe également un langage assez particulier qui devra être adapté aux besoins et au niveau de développement du jeune. Tony Ward avait initialement énoncé onze besoins fondamentaux, et le GMAP, qui est le service en Nouvelle-Zélande ayant adapté le GLM pour les adolescents, a réduit le nombre de besoins à huit. Les besoins couvriront surtout la santé (émotionnelle, en général et sexuelle) ainsi que les besoins de réalisation, d’amusement, de trouver un sens à sa vie et de développer des relations. Nous travaillerons donc beaucoup tout ce qui est du registre des émotions, soit tout d’abord pouvoir identifier ses émotions avant de pouvoir les gérer. Dans les questions en lien avec le modèle de réhabilitation, il est vrai que nous travaillons le lien social. Or, dans l’optique GLM, nous ferons d’abord passer le lien social par un lien à restaurer du jeune vis-à-vis de lui-même. Dans l’optique GLM, nous considérerons que travailler le lien social et la réparation d’un dommage vis-à-vis de la société sans se soucier d’abord d’une réparation à l’encontre du jeune est anticipé, par rapport au fait de vouloir d’emblée se lancer dans une logique de réparation. Par conséquent, un accent est mis sur une alliance thérapeutique, et le jeune se sentira beaucoup plus concerné puisque nous partirons de sa définition à lui du problème, telle qu’elle se pose pour lui avant tout. Il pourra alors retrouver un sens, et quelque part, sortir un peu de cette stigmatisation, de cet étiquetage qui lui pèse et qui est souvent lié à tout son parcours, ou qui transparaît au travers des différents rapports, des diverses rencontres avec le magistrat ou les intervenants. Cette optique de travail pourra permettre également au jeune de sortir de ses mécanismes de défense, de faciliter une distanciation par rapport aux mécanismes habituels de minimisation, de déni, d’opposition, et nous verrons que les équipes ou les intervenants qui s’imprègnent de principes liés au GLM pourront s’inscrire davantage dans des rapports relationnels s’éloignant de rapports d’opposition, de recadrage (tels que souvent vécus par les équipes). Pour revenir sur l’expérience menée aux Marronniers, il a été constaté, dans les effets au premier plan, une amélioration de la qualité relationnelle avec les patients. Ceux-ci étaient tout à fait étonnés que l’équipe se détache du travail centré exclusivement sur les passages à l’acte, la récidive, les perspectives de réhabilitation, pour s’intéresser à leurs besoins. Le deuxième effet observé concerne le bien-être des travailleurs, qui s’est traduit par une réduction significative du taux d’absentéisme. L’équipe psycho-sociale ressentant en effet davantage de plaisir à travailler les forces plutôt que les déficits de leurs patients. Avec le jeune, nous travaillons aussi la question de la responsabilité active : toujours dans la notion d’ici et maintenant, que pourra engager le jeune, par exemple si un membre de la famille est toujours très préoccupé, s’il s’agit d’un abus intrafamilial, par la réalité du risque au quotidien ? Que peut dire le jeune de son rapport à la sexualité, mais vraiment dans l’ici et maintenant et dans des perspectives futures, dans ce qu’il peut mettre en place pour rassurer sa famille ? Nous travaillons donc le projet du jeune centré sur ses besoins et son avenir, et beaucoup moins le passé. Cela ne veut pas dire qu’il n’y a pas de place pour le travail sur l’empathie, sur les habilités relationnelles, personnelles et sociales, mais nous nous recentrons d’abord sur le jeune, sur les situations d’adversité qu’il a pu rencontrer durant sa trajectoire de vie afin de favoriser une expression libre de ses émotions. Comme nous l’avons vu avec notre collègue Nadine Lanctôt, bien souvent, nous pointons du doigt tous les éléments de victimisation, maltraitance sexuelle, négligence, mais nous oublions tout l’effet des violences plus émotionnelles, plus insidieuses, qui ont également des effets tout à fait délétères sur le développement du jeune. Ainsi, nous trouvons important de travailler toute cette reconnexion du jeune à ses différents états émotionnels, afin qu’il puisse distinguer le registre des idées, des émotions, des sensations physiologiques, pour ensuite pouvoir refaire ce travail vis-à-vis du passage à l’acte. Le GLM offre un cadre conceptuel et opérationnel utile aux professionnels pour intégrer une gamme d’évaluations et d’informations, de supports théoriques et d’outils d’intervention, dans la perspective d’une compréhension riche, cohérente et complémentaire des (et avec leurs) usagers. [less ▲]

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See detailTree Ensemble Methods and Parcelling to Identify Brain Areas Related to Alzheimer’s Disease
Wehenkel, Marie ULiege; Bastin, Christine ULiege; Phillips, Christophe ULiege et al

in 2017 International Workshop on Pattern Recognition in Neuroimaging (PRNI), proceedings (2017, June)

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See detailLong-term monitoring of European eels in the Belgian Meuse River basin. From the historical drastic decline to recent outcomes of restocking practices.
Nzau Matondo, Billy ULiege; Dierckx, Arnaud ULiege; Benitez, Jean-Philippe ULiege et al

Conference (2017, June)

Long-term monitoring of yellow- and glass eel stages were performed in upland areas (>300km from sea) in order (i) to quantify the decline of wild yellow eels entering in the Belgian Meuse from the ... [more ▼]

Long-term monitoring of yellow- and glass eel stages were performed in upland areas (>300km from sea) in order (i) to quantify the decline of wild yellow eels entering in the Belgian Meuse from the Netherlands; (ii) to follow their upstream individual colonization; and (iii) to analyze the adaptation of young eels stocked as glass eels imported from UK. By monitoring a fish pass from 1992 to 2016, we quantified that the number of ascending eels has declined from n=5613 in 1992 to n=21 in 2016 (3.99%/year) and the mean length of eels has increased (4.1mm/year). During 6-years, upstream individual colonization of eels (2010-2015, n=1371) was followed using fixed RFIDtracking system. Few eels continued to migrate 4 years after tagging (<0.3%) and at >20km upstream (3.7%); and velocity of eels varied between individuals (0.012- 3.1km/day). In a 4-year (2013-2016) monitoring study of restocked glass eels using electrofishing and mobile RFID-tracking campaigns, we observed that eels grew rapidly in upland small brooks and recruitment was better in rivers with high carrying capacity (>15.8%, 2years post-stocking). Restocked eels dispersed in up- and downstream directions with behaviors including sedentary, nomadic and intermediate lifestyles. This suggests stocking as potential management measure to enhance local eel stocks. [less ▲]

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See detailA Model Reduction Approach for Simulation of Long-term Voltage and Frequency Dynamics
Weckesser, Johannes ULiege; Franz, Valeri; Grebe, Eckhard et al

in 12th IEEE PES PowerTech Conference 2017 (2017, June)

This paper presents a novel approach, which identifies a buffer zone around a given study system and replaces the external system with an equivalent. The aim is to obtain a reduced system, which is ... [more ▼]

This paper presents a novel approach, which identifies a buffer zone around a given study system and replaces the external system with an equivalent. The aim is to obtain a reduced system, which is suitable for assessment of long-term voltage and frequency dynamics in the study system. First, the proposed methodology ensures that all components, which are impacting the voltage profile of the study system, are included in the buffer zone. For that purpose, the propagation of reactive power changes from the boundary of the study system into the external system are used in a modified depth-first search algorithm to identify the buffer zone. Second, the external system is replaced with equivalents accounting for inertia and primary frequency control effects. The proposed method was successfully tested on a modified version of the ENTSO-E Dynamic Study Model. [less ▲]

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See detailTowards a Renewed Alias Resolution with Space Search Reduction and IP Fingerprinting
Grailet, Jean-François ULiege; Donnet, Benoît ULiege

in Network Traffic Measurement and Analysis Conference (TMA) (2017, June)

Since the early 2000's, the Internet Topology has been frequently described and modeled from the perspective of routers. To this end, alias resolution mechanisms have been developed in order to aggregate ... [more ▼]

Since the early 2000's, the Internet Topology has been frequently described and modeled from the perspective of routers. To this end, alias resolution mechanisms have been developed in order to aggregate all IP interfaces of a router, collected with traceroute, into a single identifier. So far, many active measurement techniques have been considered, often taking advantage of specific features from network protocols. However, a lot of these methods have seen their efficiency decrease over time due to security reinforcements across the Internet. In this paper, we introduce a generic methodology to conduct efficient and scalable alias resolution. It combines the space search reduction of TreeNET (a tool for efficiently discovering subnets) with a fingerprinting process used to assess the feasibility of several state-of-the-art alias resolution methods, using a small, fixed amount of probes. We validate our method along MIDAR on an academic groundtruth and demonstrate that our methodology can achieve similar accuracy while using less probes and discovering subnets in the process. We further evaluate our method with measurements made on PlanetLab towards several distinct ASes of varying sizes and roles in the Internet. The collected data shows that some properties of our fingerprints correlate with each other, hinting some observed profiles could be linked with equipment vendors. Both TreeNET (which implements our methodology) and our dataset are freely available. [less ▲]

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See detailIntermodal transport: does a wider definition improve its competitiveness?
Mostert, Martine ULiege; Limbourg, Sabine ULiege; Caris, An

Conference (2017, June)

With the opening of borders and always greater decentralization of production, freight transport increased a lot in the last decades. Road remains the most used mode in Europe (Eurostat, 2016). Even if it ... [more ▼]

With the opening of borders and always greater decentralization of production, freight transport increased a lot in the last decades. Road remains the most used mode in Europe (Eurostat, 2016). Even if it is appreciated for its responsiveness, flexibility, and quickness, road transport is however responsible for negative impacts on its environment like air pollution or climate change. Intermodal freight transport i.e. the transportation of goods using two or more modes of transport, in the same loading unit, without handling of the goods themselves (United Nations, 2001) is identified by the European Commission (2011) as an interesting solution for limiting the negative impacts of transport. In the classical conception of intermodal transport, pre- and post-haulage travels are supposed to be short, and to be performed by road transport, whereas the long-haul travel is done using rail or IWW. The combination of these modes allows reducing the negative externalities of the whole travel, i.e. the negative impacts that are generated by transport operators, but which are not directly supported by them. These externalities in particular consist in air pollution and climate change, provoked by the release of emissions which lead to air pollution and human health problems. The objective of this study is to determine the impact on intermodal attractiveness of allowing other combinations of modes than the classical road-rail/IWW-road combination, during an intermodal travel. The research is based on tools of the operations research domain and proposes the development of an allocation model for freight transport at the strategic level of decision. The goal is to determine the flow distribution of goods between direct transportation by road, rail or inland waterways, and any combination of these modes using intermodal transport. The novelty consists in taking into account three modes of transport in a mixed integer programming model, and to allow the transfer from any mode to any other at intermodal terminals where these modes coexist. [less ▲]

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See detailE-CLOUD, the open microgrid in existing network infrastructure
Vangulick, David ULiege; Cornélusse, Bertrand ULiege; Vanherck, Thierry et al

in Proceedings of the 24th International Conference on Electricity Distribution (2017, June)

The main goal of the E-Cloud, as with every microgrid, is to maximize the consumption of energy produced locally. To reach this goal, based on consumption profiles of customers willing to participate in ... [more ▼]

The main goal of the E-Cloud, as with every microgrid, is to maximize the consumption of energy produced locally. To reach this goal, based on consumption profiles of customers willing to participate in the E-cloud and given some local restrictions (e.g. wind turbines cannot be put everywhere), an optimal mix of green generation sources (in kW) and local storage (in kWh) needs to be computed. Then according to this computation, the required generating units and storage device are installed. A repartition mechanism grants the customer a share of the generated electricity and storage capacity. These shares are either computed offline, or dynamically adapted on line. The project will test two models: either the DSO or a producer owns and operates the storage device. Two flows of information (real-time for operation of the storage facility and ex-post for its settlement) are needed to correctly manage the E-Cloud and to ensure correct information exchange with the wholesale market. These information flows are completed thanks to a forecast that provides members of the E-Cloud the full capability to anticipate and obtain the maximum benefits of the local generation. The expected benefits for the customer are a reduction of their electricity bill by a minimum of 10%. Societal benefits should also arise: 1) easing the technical integration of renewables’ generation embedded in the distribution network, and 2) avoids extra investment on the DSO network. The E-Cloud may also ensure new revenue for the DSO thanks to new services provided to the E-Cloud community. [less ▲]

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See detailDe la Wallonie à l'Europe, les communautés de l'innovation (KIC) se mettent au service de la valorisation des déchets métalliques.
Pirard, Eric ULiege

in Pin, Dominique; Thibault, Olivier (Eds.) DES TERRITOIRES À L’EUROPE : Construire ensemble les transitions environnementales (2017, June)

La vallée de la Meuse, un des creusets historiques de la métallurgie européenne, accueille plusieurs projets d’innovation technologique dédiés au recyclage des métaux. Basés sur un partenariat public ... [more ▼]

La vallée de la Meuse, un des creusets historiques de la métallurgie européenne, accueille plusieurs projets d’innovation technologique dédiés au recyclage des métaux. Basés sur un partenariat public-privé au sein du pôle wallon Mecatech, ces projets visent à positionner la Wallonie comme une communauté de l’innovation au cœur du nouveau consortium européen EITRawMaterials. [less ▲]

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See detailLocal Control of AC/DC Converters for Frequency Support Between Asynchronous AC Areas
Papangelis, Lampros ULiege; Debry, Marie-Sophie; Panciatici, Patrick et al

in IEEE PES 2017 PowerTech conference proceedings (2017, June)

This paper proposes a novel control scheme for frequency support among asynchronous AC areas through HVDC grids. It is based on local controllers, each acting on a voltage source converter, using locally ... [more ▼]

This paper proposes a novel control scheme for frequency support among asynchronous AC areas through HVDC grids. It is based on local controllers, each acting on a voltage source converter, using locally available measurements only, and supporting frequency of the adjacent AC area after a significant disturbance. The controller is combined with the existing DC voltage droop technique and is inspired of Model Predictive Control, taking into account various constraints. The coordination of the proposed control scheme with the existing secondary frequency control of an AC area is also discussed. Examples obtained from a test system with a five-terminal DC network connecting two asynchronous areas demonstrate the effectiveness of the proposed control scheme. [less ▲]

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See detailThe Delivery of Bad News to Customers in Service Encounters: An Employee Perspective
Delcourt, Cécile ULiege; Gremler, Dwayne; Greer, Dominique

Conference (2017, June)

During service encounters, customer contact employees often need to deliver bad news: unexpected information contrary to the customer’s wellbeing. For example, technicians regularly tell customers that ... [more ▼]

During service encounters, customer contact employees often need to deliver bad news: unexpected information contrary to the customer’s wellbeing. For example, technicians regularly tell customers that none of the data on their computer hard drive can be retrieved, veterinarians often inform owners that a beloved pet has cancer and cannot be cured, and airline staff regularly tell travelers that their flights have been cancelled due to bad weather. For some customer-contact employees, delivering bad news is an unavoidable, delicate, and emotionally-charged task that occurs regularly. Disclosing bad news can be highly stressful and perhaps detrimental for (1) customers, (2) customer- contact employees, and (3) service firms in general. Accordingly, it is crucial for service organizations to better understand bad news encounters (i.e., situations during which customer contact employees must deliver negative information) to better equip their managers and employees to deliver such news to customers. The topic of how to best deliver bad news has been broached in various disciplines, including the medical literature (e.g., Baile et al. 2000, 2002; Rosenbaum et al. 2004), the management literature (e.g., Bies 2013; Kothari, Shu, and Wysocki 2009), and the sociology literature (e.g., Clark and LaBeff 1986). These literatures have (1) examined the attitudes and emotions of the discloser of extreme bad news in very specific contexts, (2) identified the tactics used by disclosers, and (3) developed protocols for delivering extremely negative information. Surprisingly, studies of bad news delivered by contact employees are scarce in service research. Service failure and service recovery have received much attention, but this literature has two major gaps when it comes to understanding the delivery of negative information. First, service recovery research generally skips over the initial part of the process where employees first communicate bad news to customers, and instead focuses primarily on the process involved to resolve the situation. Second, there are many situations in which employees must deliver negative information to customers where it is clear that a service failure has not occurred (e.g., informing a customer that his 30-year old dishwasher is beyond repair). We use the critical incident technique (CIT) (Flanagan 1954; Gremler 2004) to analyze 200 incidents where service employees from a wide range of service sectors had to deliver bad news to a customer. [less ▲]

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See detailReference interval determination for serum and urine aldosterone for healthy Belgian population
LE GOFF, Caroline ULiege; Fabregat Cabello, Neus ULiege; Huyghebaert, Loreen ULiege et al

in Clinical Chemistry & Laboratory Medicine (2017, June)

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See detailNew data on the Mesozoic radiation of chelonioids
Scavezzoni, Isaure ULiege; Fischer, Valentin ULiege

Poster (2017, June)

"Turtles" (Testudines) form a successful group of reptiles with several terrestrial, marine and fresh-water species. Their peculiar and somewhat constrained morphology (i. e. : carapace incorporating ribs ... [more ▼]

"Turtles" (Testudines) form a successful group of reptiles with several terrestrial, marine and fresh-water species. Their peculiar and somewhat constrained morphology (i. e. : carapace incorporating ribs, curved limbs, anapsid skull exempt of temporal fenestrae) and ecology has often obscured their relationships and, hence, their evolutionary history, notably in marine turtles (chelonioids). Modern chelonioids are divided in two clades (i. e. : shoft-shelled turtles and hard-shelled turtles) supported by distinct morphological and embryological characters. Their origin is traced back up to the Cretaceous, along with a series of extinct forms, many of which being collectively known as Protostegidae. Fossil evidence show that at least five clades of marine turtles were roaming the seas at the end of the Cretaceous. In fact, chelonioids appeared during the first stages of the Early Cretaceous and quickly exploded to reach a high level of disparity at the lowermost part of the late Cretaceous. Therefore, the Mesozoic radiation of chelonioids must have happened during the "middle" Cretaceous (especially the Aptian-Albian interval). However this radiation is poorly understood as the phylogenetic relationships of marine turtles are not resolved yet. Bringing new data may help resolve these issues, and it is the exact reason why the genus Rhinochelys is being investigated. [less ▲]

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See detailUnifying lesion masking and tissue probability maps for improved segmentation and normalization
Phillips, Christophe ULiege; LOMMERS, Emilie ULiege; Pernet, Cyril

Poster (2017, June)

Nowadays “Unified Segmentation” (US) is the usual approach to warp brain images into a standard reference space, i.e. perform spatial normalization, and derive posterior probability maps of the brain ... [more ▼]

Nowadays “Unified Segmentation” (US) is the usual approach to warp brain images into a standard reference space, i.e. perform spatial normalization, and derive posterior probability maps of the brain tissues, typically grey and white matter (GM, WM) and CSF [1]. US only relies on a spatial deformation model and prior ‘tissue probability maps’ (TPM) of the head tissues. When dealing with data from patients with focal brain lesions, e.g. tumors or multiple sclerosis (MS) lesion, the standard US approach does not work as it cannot account for the abnormal tissue distribution. A common work around is “cost function masking” (CFM) [2,3] where the abnormal tissues are masked out using a binary mask of the lesion [6,8]. Here we extend the US approach to provide a more principled solution for brain images with focal lesions. The aim is twofold: a more accurate warping into the reference space of the healthy tissues and a more precise delineation of the lesion(s). We modify the standard TPM adding a subject-specific ‘lesion probability map’ [5,7], by 1/ estimating a preliminary spatial warping from subject to the reference space with the CFM approach, then 2/ carefully updating the TPM with a new tissue class, the lesion, defined from the smoothed warped lesion mask and deciding which healthy tissue class can be affected by the lesion. The TPM-with-lesion is then fed into the US with the patients images, see Fig. 1. This “US-with-Lesion” (USwL) approach thus accounts for the presence of focal abnormal tissues in a probabilistic way, providing posterior probability maps of the tissues, including the lesion, and spatial deformation, accounting for the lesion. We tested and evaluated our USwL approach on 2 publicly available datasets: the BRATS [4] and the ‘MS lesion segmentation challenge’ (MSchal)[8]. The BRATS data include T1 and FLAIR images of 30 patients with gliomas and their annotated tumor mask (further considered as the ground truth). A rough lesion mask was manually built from the FLAIR image using MRIcron. USwL was used to segment T1 and FLAIR images along with this approximate mask. The GM, WM and CSF tissue classes could be affected by the lesion. The posterior probability map for the lesion tissue was cleaned up (preserving the bigger clusters) and thresholded. Overall the USwL improved (p<.05) the similarity of the lesion mask to the annotated tumor, in term of voxel matching (sensitivity, specificity & Jaccard coefficient). Synthetic lesioned brains were also generated to assess the quality of the deformation for the healthy tissues, indicating the superiority (p<.05) of the USwL compared to the standard approach. The MSchal data include T1, T2 and FLAIR images of 20 patients with MS as well as the manually annotated lesion (considered as only approximate here). USwL is applied on the 3 structural images with the lesion mask provided and with the constraint that only the WM is potentially affected by the lesion (as is plausible with MS). The thresholded posterior probability map for the lesion tissue was compared to the provided lesion mask. The USwL lead to more biologically plausible lesion volumes (p<.05), in term of volume compactness [10], see Fig. 2. The similarity of the warped posterior GM maps across the 20 subjects (expressed as the root-mean square difference to the mean of the 20 subjects) was also examined. The improvement, from using CFM-US to USwL, in the between-subject GM-matching is proportional (p<.05) to the actual WM lesion volume. We provide a new tool for US that allows to include focal lesions. Over the 2 dataset considered, USwL demonstrated improved performances compared to the standard US: 1/ a more accurate warping into the reference space of the healthy tissues and 2/ simply using an approximate mask, a more precise delineation of the lesion(s). The whole code will be made available as an SPM add-on toolbox (with a batch interface) on https://github.com/CyclotronResearchCentre/USwithLesion. [less ▲]

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See detail[18F]BPAM121: An AMPAR Modulator with Potential as a PET Probe
Manos-Turvey, Alexandra ULiege; Lemaire, Christian ULiege; Deverdenne, François et al

Poster (2017, June)

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See detailQuantification of serum androstanediol glucuronide
LE GOFF, Caroline ULiege

in Clinical Chemistry and Laboratory Medicine (2017, June)

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See detailDraw me a sheep: a pedagogical tool to discover the complexity of rural planning
Schmitz, Serge ULiege

Conference (2017, June)

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See detailQuantification of roots by the use of NIR hyperspectral imaging and chemometrics
Eylenbosch, Damien ULiege; Baeten, Vincent; Bodson, Bernard ULiege et al

Poster (2017, June)

Roots, the belowground part of plants, play a major role in plant development. Their study in field conditions is important to identify suitable soil management practices for suitable crop production but ... [more ▼]

Roots, the belowground part of plants, play a major role in plant development. Their study in field conditions is important to identify suitable soil management practices for suitable crop production but roots are hidden by soil and their study is therefore difficult. Estimation of root system development is often based on the soil coring method which allows repeated measurements during the growing season in the field as well as in different soil horizons. However, this method is limited due to the time needed to extract roots from soil cores and to manually sort them from crop residues before quantification. To avoid this tedious sorting step and remove operator subjectivity, a faster sorting method was developed. Near infrared hyperspectral imaging (NIR-HIS) was tested as a rapid method to quantify the amount of roots in soil samples. [less ▲]

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See detailImpact of an ultra-trail of 330 km on plasma levels
LE GOFF, Caroline ULiege; Kaux, Jean-François ULiege; Gergelé, Laurent et al

in Clinical Chemistry and laboratory medicine (2017, June)

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See detailProfiling inferior left dorsal premotor cortex: when Area 55b meets Premotor Eye-Field
Genon, Sarah ULiege; Reid, Andrew; Langner, Robert et al

Poster (2017, June)

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See detailAccuracy improvement in digital holographic-based speckle correlation for three-dimensional (3D) displacement measurement
Zhao, Yuchen ULiege; Zemmamouche, Redouane; Vandenrijt, Jean-François ULiege et al

in Digital Holography and Three-Dimensional Imaging (2017, June)

Combination of digital holography and speckle correlation for three-dimensional displacement measurement suffers from inaccuracy. Speckle size adjustment and phase error correction during the digital ... [more ▼]

Combination of digital holography and speckle correlation for three-dimensional displacement measurement suffers from inaccuracy. Speckle size adjustment and phase error correction during the digital holography process can improve the accuracy of in-plane displacement measurement. [less ▲]

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See detailUsing electric vehicles as flexible resource in power systems: A case study in the Netherlands
Beltramo, Agnese; Julea, Andreea; Refa, Nazir et al

in Proceedings of the 14th International Conference on the European Energy Market (2017, June)

The European Union (EU) is actively encouraging member countries to phase out traditional oil-fuelled cars in cities in favour of Electric Vehicles (EV) as a solution for increasing efficiency ... [more ▼]

The European Union (EU) is actively encouraging member countries to phase out traditional oil-fuelled cars in cities in favour of Electric Vehicles (EV) as a solution for increasing efficiency, contributing to ensure security of supply, decrease CO2 emission and decrease local (especially urban) air pollution coming from the transport sector. With the increasing associated charging infrastructure deployment all over European countries, the demand coming from these technologies might impact the power system and potentially offer a source of flexibility through variable charging profiles and battery storage capacity options. In the recent years, the Dutch government has adopted several policy support mechanisms for EVs uptake, which made the Netherlands the country with the highest market share of electric cars in 2015 in the EU, and the second-highest share worldwide after Norway. This country is therefore a unique case study for the analysis of EVs charging demand and impact of the power sector. The recent uptake of EVs provides a significant amount of historical data regarding charging profiles, connection times or utilisation patterns pertaining this technology. This paper aims at exploiting such data to evaluate the current and future impact of electric vehicle deployment on the power system. To that end, historical data from 2015 are used in conjunction with the Dispa-SET model, a unit commitment and power dispatch model developed at the Joint Research Centre (JRC) of the European Commission. This aims at investigating the impact of Battery Electric Vehicle (BEV) charging demand on the current Dutch power system, under different hypotheses for BEV technology penetration and renewable energy deployment (i.e. wind and solar) in the country. In addition, looking at the entire connection periods when vehicles are plugged to the grid, the battery capacity connected to the system is estimated, based on commercial BEV battery characteristics. This total capacity is finally used as variable storage unit in the model, in order to investigate the impact that Vehicle to Grid (V2G) strategies could have on the optimal use of power resources available, with particular attention to Variable Renewable Energy (VRE). [less ▲]

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See detailEffect of grinding on bone detection by light microscopy: Study results
Lecrenier, Marie-Caroline ULiege; Veys, Pascal; Planchon, Viviane et al

Conference (2017, June)

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See detailExperimental design helps to optimize spray drying processes
Dellicour, Aline ULiege; Cloots, Rudi ULiege; Boschini, Frédéric ULiege

Poster (2017, June)

Experimental design is necessary to identify major experimental parameters linked to a process in order to optimize it and reduce costs. It also helps to reduce the number of experiments and analyze data ... [more ▼]

Experimental design is necessary to identify major experimental parameters linked to a process in order to optimize it and reduce costs. It also helps to reduce the number of experiments and analyze data statistically. This work aims to present some possibilities of how experimental design may be applied in the field of pharmaceutical powders production by spray drying. Depending on the application, powders need particular size, morphology, purity, crystallinity or polymorphism. All these characteristics may be influenced by process parameters and should be controlled to reach pharmaceutical requirements. [less ▲]

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See detailStaggered strong coupling between existing fluid and solid solvers through a Python interface for fluid-structure interaction problems
Thomas, David ULiege; Variyar, Anil; Boman, Romain ULiege et al

in Proceedings of the VII International Conference on Coupled Problems in Science and Engineering (2017, June)

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See detailCo-creating service recovery after service failure: The role of brand equity
Hazee, Simon ULiege; Van Vaerenbergh, Yves; Armirotto, Vincent

Conference (2017, June)

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See detailThe Use of Inflammatory Markers in Field Cattle Medicine
Guyot, Hugues ULiege

in ACVIM Forum Proceedings (2017, June)

Numerous cow-side diagnostic tests are available for bovine practitioners. Many of these tests serve etiologic purposes such as quick test for diarrhea or measures of metabolites directly linked to ... [more ▼]

Numerous cow-side diagnostic tests are available for bovine practitioners. Many of these tests serve etiologic purposes such as quick test for diarrhea or measures of metabolites directly linked to pathologies (BOH or ions Ca++, Na+, K+, etc.). Beside these interesting elements, inflammation, which is either a cause or a consequence of a specific disease, is often forgotten. This presentation will refresh the practitioner’s knowledge on the assessment of inflammation in cattle by using inflammatory markers assayed with laboratory and cow-side tests. The interpretation of these markers can be sometimes delicate (bias) and might not necessarily lead to a prognosis. Depending on the age of the animal, some inflammatory markers can also serve as diagnosis for other purposes such as the evaluation of passive immunity transfer in calves. [less ▲]

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See detailEstablishment of reference values for 6 six steroids in serum
LE GOFF, Caroline ULiege; Fabregat Cabello, Neus ULiege; Huyghebaert, Loreen ULiege et al

in Clinical Chemistry and Laboratory Medicine (2017, June)

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See detailThe question of the methane increase though the retrieval of its isotopologues from FTIR ground-based observations
Bader, Whitney ULiege; Strong, Kimberley; Walker, Kaley et al

Conference (2017, June)

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See detailOn the transition between symmetric ans asymmetric flow in rectangular shallow reservoirs - a case of maximum energy dissipation?
Westhoff, M.C.; Erpicum, Sébastien ULiege; Archambeau, Pierre ULiege et al

Conference (2017, June)

Shallow reservoirs are often used in hydraulic engineering as sediment traps or storage basins. For short rectangular reservoirs, the main jet flows straight from the inlet to the outlet with on both sides ... [more ▼]

Shallow reservoirs are often used in hydraulic engineering as sediment traps or storage basins. For short rectangular reservoirs, the main jet flows straight from the inlet to the outlet with on both sides symmetric recirculation zones. In longer reservoirs, however, the main jet reattaches to the side of the reservoir leading to a small and a large recirculation zone. Previous studies have found an empirical geometric relation describing the switch between these two flow pattems. In this study, we demonstrate with a simple analytical model, that this switch in flow pattem coincides with a maximization of energy dissipation in the shear layer between the main jet and the recirculation zones. We show that for short reservoir lengths, energy dissipation is higher in the case of a symmetric fiow pattern, while for longer reservoir the energy dissipation is higher for asymmetric flow pattems. The simulated switch between the two flow patterns appears to be very close to the empirical relation. The strength of this approach lies in the fact that no detailed knowledge of small scale processes is needed, which may prove useful at an early stage of reservoir design. [less ▲]

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See detailEvaluation of Non-negative matrix Factorization of grey matter in age prediction
Varikuti, Deepthi; Genon, Sarah ULiege; Sotiras, Aristeidis et al

Poster (2017, June)

Introduction: It has been shown that machine-learning methods applied to voxel-based morphometry (VBM) data allows the prediction of brain age [1]. Dimensionality reduction is a critical aspect of such ... [more ▼]

Introduction: It has been shown that machine-learning methods applied to voxel-based morphometry (VBM) data allows the prediction of brain age [1]. Dimensionality reduction is a critical aspect of such brain-based prediction of phenotypical characteristics to counter the curse of dimensionality associated with voxel-wise analysis. While previous age-predictions have employed PCA based compression, non-negative matrix factorization (NNMF) has recently been suggested as a plausible factorization of high-dimensional VBM data [4]. Non-negativity and sparsity of the components obtained from NNMF facilitate relatively more optimal solution than the PCA based compression [4]. Here, we evaluate, i) whether NNMF compression allows predictions of biological age that reproduce those from previously reported analyses [2], ii) the impact of the NNMF’s granularity on the prediction accuracy, iii) the possible effect of the factorizations derived from different datasets on the prediction, and iv) whether explicit adjustment can address the model bias inherent to many brain-based predictions. Methods: VBM8 preprocessing (using only non-linear modulation and 8 mm FWHM smoothing [3]) was used to compute voxel-wise GM volumes for two datasets, 1) 693 healthy older adults (age: 55-75 years) scanned at a single site (“1000BRAINS) [1], 2) 1084 healthy adults (age: 18-81 years), scanned at multiple sites (“Mixed”) (Fig 1A). NNMF solutions for both groups were derived at different levels of granularity. Age prediction was performed by fitting LASSO regression models either on the coefficient matrix from the respective NNMF or by those that were derived from projecting a group’s data on the respective other groups components. Model generalization was evaluated by 10-fold cross-validation replicated 25 times. To address the known bias towards the mean, i.e., overestimation of young and underestimation of older subjects, we additionally tested models that explicitly fitted the regression-slope between the real and predicted training set and used this to adjust the expected slope of the test set to 45 degrees. Results: In both datasets, NNMF components resembled neurobiologically reasonable patterning of the brain (Fig 1B). Prediction accuracy based on the projection of data on the components from either group was virtually identical (Fig 2A). For both datasets, mean absolute errors (MAE) declined with higher granularity of the components and reached values well comparable to previous approaches even when using components derived from an independent sample (MAE: 3.6 years for 1000BRAINS; 6.4 years for Mixed). Plotting the prediction error relative to the biological age of the subjects revealed the bias towards the mean across both datasets (Fig 2B). Adjusting for the slope estimated in the training set allows removing this bias, though it needs to be noted that this comes at the cost of reduced precision, i.e., unbiased estimates yield a slightly higher MAE. Conclusion: NNMF allows the definition of co-variation patterns in VBM data. Due to the non- negativity and sparseness, NNMF enable substantially easier and higher biological interpretation than other methods for data compression such as PCA [4]. We showed that NNMF compression of VBM data over the lifespan allows predicting previously unseen subjects’ age with a precision that is comparable to earlier reports using PCA for data compression [2], while offering the potential for neurobiological interpretation. Importantly, accuracy seems to be independent of whether the components were derived from the same dataset or from a dataset that is not only independent but also different in age distribution. We note that accuracies tend to continuously decrease with higher granularity, although performance tends to plateau at about 300 components. Finally, adjusting the inherent bias of sparse regression models yields unbiased out-of-sample predictions but comes at the expense of slightly higher mean errors. [less ▲]

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See detailDevelopment of a unified model for flow-material interaction applied to porous charring ablators
Coheur, Joffrey ULiege; Schrooyen, Pierre; Turchi, Alessandro et al

in 47th AIAA Thermophysics Conference : AIAA Aviation Forum, 5-9 June, Denver, CO (2017, June)

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See detailResilience of the DSO network near to 50.2Hz
Vangulick, David ULiege; Ernst, Damien ULiege; Van Cutsem, Thierry ULiege

in Proceedings of the 24th International Conference on Electricity Distribution (2017, June)

In an electrical system where decentralized and embedded productions are becoming more and more important, it is essential to ensure there is a good understanding of their behaviour at their operating ... [more ▼]

In an electrical system where decentralized and embedded productions are becoming more and more important, it is essential to ensure there is a good understanding of their behaviour at their operating limits. One the most important operating limits is when the system frequency approaches 50.2 Hz. At this frequency, following the old requirements, many existing European PV inverters have to be disconnected. In such situations, we will demonstrate that the variance of the frequency measurement taken at every PV inverter plays a key role. It will be demonstrated that this variance is actually a good thing from the system’s point of view as it allows for a gradual disconnection, leading to a controlled variation of the frequency. [less ▲]

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See detailSeparation of FLEC diastereomers by CE vs. LC approaches in the context of neurometabolomics
Moldovan, Radu-Cristian ULiege; Bodoki, Ede; Servais, Anne-Catherine ULiege et al

Poster (2017, June)

Some of the D-amino acids (D-Ser, D-Asp, D-Glu) have gained an increasing attention during the last decades, due to the discovery of their role as neurotransmitters and their implication in different ... [more ▼]

Some of the D-amino acids (D-Ser, D-Asp, D-Glu) have gained an increasing attention during the last decades, due to the discovery of their role as neurotransmitters and their implication in different neurological pathologies (Alzheimer’s disease, schizophrenia etc.). Nevertheless, their use as biomarkers is particularly relevant when correlated with the levels of other neurotransmitters. In order to develop a fast and efficient separation method widely accessible for the quantitation of these molecules, we used only common separation tools such as RP-18 stationary phases for reversed phase liquid chromatography (RP-LC) or bare fused capillaries for capillary zone electrophoresis (CZE). For achieving chiral resolution, a derivatization procedure was implemented. (-)-FLEC was the chiral derivatization agent of choice due to its fast and quantitative reaction with primary and secondary amines and the ability of performing in-capillary derivatization. Moreover, the derivatization process implies only a simple mix of the sample and reagent, at room temperature. The separation of the FLEC derivatives of several biologically relevant D- and L- amino acids (Asp, Glu, Ser, Tyr, Trp, Phe, His) together with certain neurotransmitter molecules have been optimized using CZE or RP-LC, chiral resolution being achievable for all amino acids of interest. By the CZE approach the running buffer’s pH turned out to be critical in achieving baseline separation of the targeted analytes. The derivatives of most amino acids could be separated using 60mM acetate buffer at pH 5, while for Asp derivatives the separation could be achieved only at pH 4. Being stronger bases, a third run at a more alkaline pH was needed for the separation of the remainder neurotransmitters. Moreover, the implemented in-capillary derivatization allows a fast and fully automated separation procedure. As for the RP-LC approach 50 mM acetate buffer in combination with an organic modifier (methanol, acetonitrile or tetrahydrofuran (THF)) was tested as mobile phase using gradient elution. Once again, the strong influence of pH on the resolution was observed. The organic modifier nature was of critical importance, where only THF enabled baseline resolution for all amino acid derivatives. [less ▲]

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See detailUntargeted serum metabolite profiling of colorectal cancer using GC-Orbitrap technology
Di Giovanni, Nicolas ULiege; Cojocariu, C; Silcock, P et al

Poster (2017, June)

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See detailHic Sunt NATs: Uncovering Address Translation with a Smart Traceroute
Zullo, Raffaele; Pescapé, Antonio; Edeline, Korian ULiege et al

in IEEE/IFIP Workshop on Mobile Network Measurement (MNM) (2017, June)

Middleboxes are pervasive in today's Internet as they are deployed for an increasing number of reasons. An example is the network address translation (NAT), one of the first task to be performed to cope ... [more ▼]

Middleboxes are pervasive in today's Internet as they are deployed for an increasing number of reasons. An example is the network address translation (NAT), one of the first task to be performed to cope with the lack of IPv4 addresses. Recently the landscape for NATs has become even more crowded, especially in mobile networks, mainly due to the impossibility of IPv6 to be a large-scale solution to addressing issues. In this paper, we present a novel methodology for detecting NATs embodied in Mobile Tracebox, a measurement tool for Android smart devices that detects a wide range of middleboxes. It analyzes ICMP time-exceeded messages received during \traceroute and points at IP and transport checksum inconsistencies in the embedded packets to uncover address translation along a path. We deployed Mobile Tracebox through a crowdsourcing approach and used the collected dataset to validate our methodology. Results showed that, in absence of middleboxes breaking \traceroute, it can help to detect and locate NATs in the majority of the cases. [less ▲]

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See detailMultimodal imaging analysis in Charles Bonnet Syndrome: a case report
Martial, Charlotte ULiege; Di Perri, Carol ULiege; Larroque, Stephen Karl ULiege et al

Poster (2017, June)

Charles Bonnet syndrome (CBS) is a rare condition characterized by visual impairment associated with complex visual hallucinations in psychologically normal elderly people. Previous studies have suggested ... [more ▼]

Charles Bonnet syndrome (CBS) is a rare condition characterized by visual impairment associated with complex visual hallucinations in psychologically normal elderly people. Previous studies have suggested that visual hallucinations may be caused by brain damage in the visual system. However, in the case of CBS, specific brain regions in the occipital cortex have not been clearly determined and functional neuroimaging remains relatively unexplored. To our knowledge, functional connectivity by means of resting-state magnetic resonance imaging (MRI) has never been investigated in patients with CBS. We here aimed to investigate structural imaging, brain metabolism and functional connectivity in a patient with CBS. Resting-state functional and structural MRI were acquired in an 85-year-old patient with CBS and 12 age- and gender-matched normally sighted controls. Cognitive functioning was measured by behavioral assessment. A seed-based resting state fMRI was performed to investigate the default mode network (DMN), the executive control network and the visual networks connectivity. A voxel-based morphometry (VBM) analysis was employed to investigate the grey matter volume. Cortical and subcortical grey matter thickness were further investigated. Finally, 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) was also acquired to observe regional glucose uptake by comparing standard uptake values (SUVs). Increased functional connectivity was found between the DMN and the temporo-occipital fusiform cortex, as well as between the secondary visual cortex and the left frontal cortex, in the CBS patient compared to controls. The patient also demonstrated increased functional connectivity between the primary visual cortex and the left supramarginal gyrus and between the associative visual cortex and the superior temporal gyrus/angular gyrus, as compared to controls. Decreased grey matter volume was observed in the lateral occipital cortex/angular gyrus in our patient as compared to controls. Diminished grey matter thickness values were observed in the lateral geniculate nucleus compared to healthy controls. FDG-PET results confirmed previous work and showed bilateral hypometabolism in the occipital cortex (mean SUV reduction of 5.36%, p<0.001). Our results suggest that structural alterations in visual system in CBS are associated with compensatory/adaptive changes in functional connectivity that involve regions known to support hallucinations of faces in CBS patients. We suggest that this functional connectivity reorganization following visual structural damage may contribute to visual hallucinations. These findings might shed light on the pathophysiology underlining this rare condition. [less ▲]

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See detailSafety update on dapagliflozin (DAPA) across the phase 2b/3 clinical trial program
Jabbour, Serge; Seufert, Jochen; SCHEEN, André ULiege et al

Poster (2017, June)

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See detailNGOs and female circumcision in Egypt. An anthropological enquiry
Mescoli, Elsa ULiege

in The Journal of the Anthropology of the Contemporary Middle East and Central Eurasia (2017, June)

In 1994, during the International Conference on Population and Development convened by the United Nations in Cairo, a shocking video was shown, realized by an operator of CNN and depicting the ... [more ▼]

In 1994, during the International Conference on Population and Development convened by the United Nations in Cairo, a shocking video was shown, realized by an operator of CNN and depicting the circumcision of a ten-year-old child living in this very same city. Discourses around female circumcision were not new in Egypt and in the international community, but what was considered as a new episode of a recurrent scandal (not the last one indeed) led to enhance the “war against bad government” (Foucault 2003: 38). A war fought by means of ideological weapons produced by various forms of expert knowledge among which the medical and the feminist ones. The assignment of a value to the state of integrity of the female body and to the women freedom of choice, both designed according to Western canons, led to different actions to “save” Egyptian women. In this context, development agencies foster a widespread representation of the victim, constituted by the woman mutilated body. Such representation is functional to put in place programs which do not guarantee a freedom of choice, but rather require adherence to another female model, one that defines the "modern" woman. My article, based on ethnographic experience, aims at highlighting the complexity of such dynamics and the role played by humanitarianism within them. Female body becomes the arena where local and international economic powers operate, disregarding a real understanding of the practice, its meanings and its eventual change. [less ▲]

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See detailComparison of cardiac biomarker fluctuation in runners of marathons, semi-marathons and untrained runners
LE GOFF, Caroline ULiege; VRANKEN, Laura ULiege; van Nueten, Jan et al

in Clinical Chemistry & Laboratory Medicine (2017, June)

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See detailMarket Efficiency And Hedge Fund Trading Strategies
Lambert, Marie ULiege

Conference (2017, May 31)

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See detailNON-PATHOLOGICAL AGING OF THE EXECUTIVE FUNCTIONS: INFLUENCE OF THE VAL108/158MET NUCLEOTIDE POLYMORPHISM OF THE COMT GENE
Gilsoul, Jessica ULiege; Manard, Marine ULiege; Collette, Fabienne ULiege

Conference (2017, May 31)

Introduction. According to the Dual-State Theory of prefrontal cortex dopamine, Val/Val polymorphism of the COMT gene would favor better flexibility abilities, whereas Met/Met carriers would favor better ... [more ▼]

Introduction. According to the Dual-State Theory of prefrontal cortex dopamine, Val/Val polymorphism of the COMT gene would favor better flexibility abilities, whereas Met/Met carriers would favor better stability abilities. These genotypic effects should be magnified in older people, as a decrease in cognitive resources increases the influence of individual genetic differences on cognitive performance. Therefore, the aim of the study is to investigate the influence of the COMT Val108/158Met nucleotide polymorphism on executive functions in normal aging. Method. We assessed the executive processes of inhibition, shifting, and updating thanks to many different tasks in groups of young (n = 55) and aged participants (n = 45) carrying one of the three polymorphisms of the COMT gene (Val/Val, Val/Met, Met/Met). T-tests between our two groups (Young versus Aged) but also a 6 (Group: Young-Met/Met, Young-Val/Met, Young-Val/Val, Old-Met/Met, Old-Val/Met, and Old-Val/Val) X 3 (Executive functioning: Inhibition, Shifting, and Updating) repeated measure ANOVA with Executive functioning as within-subject factor (p < .05) were carried out. Results. Young and old participants significantly differed on the three executive functions. The comparison of genotypic groups showed no significant differences in young or older participants respectively. Interestingly, the Old-Val/Val group showed a lower performance than the young one on inhibition tasks. Discussion. As expected, we found an age effect on all the executive functions. The significant difference between the Young-Val/Val and the Old-Val/Val groups on inhibition suggests an age-related decrease in abilities requiring a stability component in individuals possessing a less favoring genotype for this component. [less ▲]

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See detailLes limites de l’administration de la PCL - R à une population de sujets schizophrènes dans le contexte médico-légal
Englebert, Jérôme ULiege; Matteucci, Marie; De Page, Louis et al

Poster (2017, May 31)

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See detailRecognition memory is associated with hippocampal volume in aging population: new evidence from brain imaging study
Narbutas, Justinas ULiege; Blanpain, Manon ULiege; Van Egroo, Maxime ULiege et al

Poster (2017, May 31)

Introduction. The hippocampus is crucial for episodic memory, especially for recollection and pattern separation (i.e., the ability to store similar episodes as distinct memory traces). Episodic memory ... [more ▼]

Introduction. The hippocampus is crucial for episodic memory, especially for recollection and pattern separation (i.e., the ability to store similar episodes as distinct memory traces). Episodic memory declines with aging and this has been associated with hippocampal dysfunction. The main objective of our study was to explore how performance on a recognition memory task designed to assess pattern separation is associated with hippocampal volume in aging population. Method. Fourteen healthy late middle-aged participants (52-69 years-old) were evaluated on a Mnemonic Similarity Task (MST). In this task, participants study pictures and then have to discriminate between targets, similar lures, and unrelated foil objects. Recognition memory (RM) is assessed as the difference between hits and false alarms to unrelated foils, while pattern separation Bias metric (BPS) is the difference between the rate of ‘‘Similar’’ responses given to the lure items minus ‘‘Similar’’ responses given to the foils. Hippocampal volume was calculated using ASHS software, which uses T1-weighted and T2-weighted MRI to obtain optimal segmentation of hippocampal subfields. Results. Correlation analysis of preliminary data revealed that RM was significantly positively associated with the volume of the left subiculum and left perirhinal area 35. BPS was positively correlated with the volume of right CA2 region, but negatively associated with the volume of right CA3 region. Discussion. In a late middle-aged population, better visual recognition memory is associated with larger volume of the left subiculum and perirhinal area 35, two regions supporting representation of objects. [less ▲]

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See detailDo nonbelieved memories typically refer to childhood memories?
Vanootighem, Valentine ULiege; Brédart, Serge ULiege

Conference (2017, May 31)

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See detailNarration et argumentation. Retour sur l’analyse du discours en sciences sociales
Lttr13; Badir, Sémir ULiege; Polis, Stéphane ULiege et al

Conference (2017, May 31)

En 1979 a paru un ouvrage dirigé par A.J. Greimas et É. Landowski, intitulé « Introduction à l’analyse du discours en sciences sociales ». L’ouvrage n’a pas connu le succès de son contemporain, publié la ... [more ▼]

En 1979 a paru un ouvrage dirigé par A.J. Greimas et É. Landowski, intitulé « Introduction à l’analyse du discours en sciences sociales ». L’ouvrage n’a pas connu le succès de son contemporain, publié la même année, le célèbre « Sémiotique. Dictionnaire de la théorie du langage ». On souhaite dans cette communication proposer un bilan critique, en comparant les postulats de la méthode sémiotique avec ceux d’autres modèles d’analyse, et soulever quelques questions théoriques relatives aux types de discours. L’ouvrage de Greimas et Landowski s’inscrit dans le projet général d’extension du modèle narratif d’analyse textuelle. Selon ce projet, le modèle initialement développé en vue de l’analyse des contes et des mythes peut être appliqué à différents types de discours en envisageant dans leur variété, suivant « un degré croissant de complexité et d’abstraction », les « formes de production sociale du sens » (Greimas & Landowski, p. 5, passim). Le modèle étend ainsi la notion de récit à tout type de discours, à toute forme textuelle, ainsi que le confirme le « Dictionnaire ». Cette extension généralisée prend appui sur une typologie des discours qu’illustrent des analyses particulières publiés dans les années 1980 (Bastide 1981 ; Bastide & Fabbri éds 1985 ; Landowski 1986). Déjà en 1966, dans « Sémantique structurale », Greimas prévoyait une typologie de quatre types de « micro-univers sémantiques » (p. 128) où s’opposent, en fonction de deux critères, les univers dits « idéologiques » (dont ressortit le conte populaire) et les univers « scientifiques ». On peut considérer que la proposition de recherche qu’ont dirigée Greimas et Landowski est ainsi située au point le plus éloigné d’élaboration et d’application initiale du modèle suivi et qu’elle constitue par conséquent une expérience-limite pour le modèle narratif. Ce faisant, l’approche sémiotique prenait le risque d’être confrontée à d’autres modèles d’analyse, tels qu’ils se sont élaborés dans des cadres théoriques issus de la rhétorique (réactualisée dans les années 1950 par Chaïm Perelman et son école), de la pragmatique (cf. Parret 1983 & 1987), de la sociologie de la connaissance (à partir de l’ouvrage fondateur de Berger & Luckmann 1966) ou comme ils relèvent d’autres courants théoriques en sciences du langage (notamment, en France, l’analyse du discours d’inspiration althussérienne). Pour l’analyse des discours en sciences sociales, ces modèles offrent deux avantages sur celui de la sémiotique : d’une part, il semble que les postulats théoriques sur lesquels ils sont construits s’accordent plus directement au type que ces discours constituent ; d’autre part, ils peuvent désormais compter sur une solide tradition d’études permettant de pérenniser les résultats. La congruence apparente entre modèles d’analyse et types de discours, malgré l’extension d’applicabilité à laquelle ces modèles peuvent prétendre, soulève des questions relatives à la légitimité d’une typologie des discours. Celle-ci peut-elle se mettre au-dessus des postulats théoriques qui forgent les appariements entre modèle d’analyse et type de discours ? Si ce n’est le cas, quels enjeux la question typologique permet-elle de soulever ? Outre celle de Greimas évoquée plus haut, les tentatives qui ont été proposées à ce sujet (notamment van Dijk 1972 & 1975 ; Adam 1999 & 2011 ; Bronckart 1997 ; Maingueneau 2007), nous permettront d’en donner au moins une idée. [less ▲]

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See detailÉvaluation des impacts des ouvrages transversaux sur le transport sédimentaire et l’hydromorphologie
Peeters, Alexandre ULiege; Petit, François ULiege; Houbrechts, Geoffrey ULiege

Conference (2017, May 31)

Le transport naturel des sédiments de la charge de fond est aujourd'hui clairement identifié comme un contributeur essentiel pour atteindre le bon état écologique des cours d’eau (Directive 2000/60/CE ... [more ▼]

Le transport naturel des sédiments de la charge de fond est aujourd'hui clairement identifié comme un contributeur essentiel pour atteindre le bon état écologique des cours d’eau (Directive 2000/60/CE). Lorsque le transport sédimentaire est entravé par des obstacles, l’équilibre hydromorphologique et écologique de la rivière est alors perturbé. Ces obstacles à la continuité écologique sont nombreux dans le bassin versant du Bocq (233 km², affluent de la Meuse en Wallonie) : on en dénombre 76 sur les 135 km de linéaire de cours d'eau, ce qui représente 1 obstacle tous les 1,8 km en moyenne. Il s'agit principalement d'ouvrages transversaux liés à des usages anciens du cours d’eau (moulin, forge, abissage, pompe à eau, etc.). Dans le cadre du projet UE LIFE+ Walphy, des travaux de réhabilitation de la continuité écologique ont été réalisés entre 2009 et 2013 sur 22 ouvrages transversaux du bassin du Bocq. Avant la réalisation des travaux, plusieurs ouvrages ont fait l’objet d’un diagnostic hydromorphologique et sédimentaire, basé sur l'identification des zones impactées (remous liquide et solide) d'une part, et l'évaluation de l'effet de piégeage de l'ouvrage d'autre part. Ce dernier point repose sur la caractérisation de l'ouvrage et du remplissage de sa retenue, ainsi que sur des mesures granulométriques et des marquages de la charge de fond (transpondeurs passifs). Ainsi, nous avons mis en évidence différents cas de piégeage de la charge de fond : absent, partiel ou total. Parmi les travaux de réhabilitation de la continuité écologique, ce sont les projets de suppression d'obstacle qui sont les plus efficaces, comme l'illustre le cas du déversoir de Spontin, pour lequel nous avons quantifié les impacts de son arasement des points de vue hydromorphologique et sédimentaire. Enfin, l’aménagement d'une rampe rugueuse sur un site fortement artificialisé (lit bétonné) à contrainte importante (protection de captages d'eau potable) constitue un cas particulier de réhabilitation de la continuité écologique, pour lequel l'analyse approfondie du transport sédimentaire a fourni les éléments nécessaires au bon dimensionnement des matériaux à utiliser. [less ▲]

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See detailAutobiographical memory: from the past to the future
D'Argembeau, Arnaud ULiege

Conference (2017, May 31)

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See detailLe "Good Lives Model", un modèle novateur d'intervention au service des besoins de l'usager: Expérience d'adaptation au sein de l'hôpital psychiatrique sécurisé "Les Marronniers" à Tournai
Henrard, Noémie ULiege; Devillers, Bérengère ULiege; Oswald, Pierre et al

Conference (2017, May 31)

L’Hôpital Psychiatrique Sécurisé (H.P.S.) « Les Marronniers » de Tournai fut la première équipe francophone, en collaboration avec le Groupe Antigone, à avoir adapté le Good Lives Model (GLM) à une ... [more ▼]

L’Hôpital Psychiatrique Sécurisé (H.P.S.) « Les Marronniers » de Tournai fut la première équipe francophone, en collaboration avec le Groupe Antigone, à avoir adapté le Good Lives Model (GLM) à une population psychiatrique (GLM – FM). Le cadre théorique et méthodologique du G.L.M – FM offre la possibilité de dépasser le paradigme du risque/rechute en proposant des principes et outils qui guident l’intervention tout en tenant compte du rôle des symptômes psychiatriques/infraction et des besoins humains fondamentaux de l’usager. Le G.L.M – FM implique d’élaborer avec l’usager un « Good Live Plan », plan de vie visant à satisfaire les besoins humains fondamentaux et à accéder à une meilleure qualité de vie. Le G.L.M- FM intègre à la fois les risques et les perspectives de réadaptation, et ce, dans une approche globale, intégrée et cohérente. Objectifs : - Présenter les fondements théoriques et les principes cliniques de base qui guident le Good Lives Model - Forensic Mental Health ; - Présenter différents outils cliniques (général et spécifique) permettant l’opérationnalisation du GLM-FM ; - Développer l’expérimentation et l’adaptation du G.L.M. réalisé au sein de l’H.P.S. de Tournai au travers des projets UET et Epicéas. Méthodes d’apprentissage : - Expérimentation par les participants d’un des champs de l’outil de l’Inventaire des Souhaits et Préoccupations Personnels (ISPP) ; - Articulation des principes théoriques et cliniques ; [less ▲]

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See detailStranger harassment: perception, tolerance and the influence of gender identities and gender stereotypes
Goblet, Margot ULiege; Glowacz, Fabienne ULiege

Poster (2017, May 31)

Stranger harassment is defined as gender based harassment in public spaces. Despite its frequency and its detrimental consequences, research has barely begun to address this phenomenon. Stranger ... [more ▼]

Stranger harassment is defined as gender based harassment in public spaces. Despite its frequency and its detrimental consequences, research has barely begun to address this phenomenon. Stranger harassment is in the eye of the beholder. Gender differences and contextual factors are decisive for its interpretation (Fairchild, 2010; Rotundo, Nguyen and Sackett, 2001). The aim of this study is to estimate contextual factors of stranger harassment and more precisely to examine the influence of gender identities and gender roles on perception and tolerance of stranger harassment within a population of young women and men aged 18-35. Two methods of data collection are used, a paper questionnaire and an on-line questionnaire. The sample should include more than 600 subjects. Participants are surveyed regarding their global life satisfaction (Satisfaction With Life Scale, Diener et al., 1985), personal experiences of stranger harassment (Sexual Experience Questionnaire, Fairchild, 2010) and the context of occurrence and the consequences of those experiences on several aspects of their life. Acceptation and tolerance of sexual harassment (Sexual Harassment Attitude Scale, Mazer et Percival, 1989), identification to gender roles (short French version of Bem Sex-Roles Inventory, Fontayne et al., 2000) and experiences of sexual victimization are also addressed. Results will provide us an overview of stranger harassment and its occurrence. Some risk factors may be identified, as experiences of sexual victimization that may influence tolerance of stranger harassment. Furthermore, the influence of gender roles and gender identities may be crucial for the understanding of stranger harassment as a gender based behavior [less ▲]

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See detailFemmes auteures d’infraction à caractère sexuel en guidance sous contrainte judiciaire : entre représentations et réalités ?
Glowacz, Fabienne ULiege; Lagneaux, Julien; MALEMPRE, Marc et al

Poster (2017, May 31)

La délinquance a été le plus souvent conjuguée au masculin alors que la violence des femmes est restée longtemps ignorée. Il en est de même pour la délinquance sexuelle agie par les femmes qui est étudiée ... [more ▼]

La délinquance a été le plus souvent conjuguée au masculin alors que la violence des femmes est restée longtemps ignorée. Il en est de même pour la délinquance sexuelle agie par les femmes qui est étudiée depuis peu et est reconnue tout en étant encore méconnue. Notre étude porte sur l’analyse de 23 dossiers émanant de 4 centres de santé mentale spécialisés en Belgique qui ont notamment pour mission de dresser des avis motivés à la demande d’autorité mandante dans le cadre d’un sursis probatoire, d’une libération probatoire ou définitive. L’analyse de contenu des dossiers a permis d’identifier les caractéristiques psychologique, sociale, sexuelle et criminologique des sujets ainsi que la nature des infractions commises et le profil de victimes. Dans la lignée des travaux en matière de délinquance non sexuelle, nous avons repris plusieurs questions dont celles du statut de la femme en tant que auteure et co-auteure, de la présence de troubles psychopathologiques, de l’usage de violences physiques, des antécédents judiciaires ainsi que des dynamiques familiales dans lesquelles elles ont évolué. Plus spécifiquement à la délinquance sexuelle, la sexualité et le rapport aux victimes et les victimisations antérieures ont été analysées pour compléter le portrait du fonctionnement de ces femmes. Les résultats de cette étude ont été confrontés aux représentations des travailleurs de ces centres recueillis à partir de Focus group. [less ▲]

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See detailChanges in preoptic estradiol concentrations during male sexual behavior
de Bournonville, Marie-Pierre ULiege; de Bournonville, Catherine; Ball, Gregory et al

in Frontiers in Neuroscience (2017, May 30)

Besides its long-term control by steroids, male sexual behavior is also modulated by membrane-initiated effects of neuroestrogens in the short-term (within minutes). These effects are thought to depend on ... [more ▼]

Besides its long-term control by steroids, male sexual behavior is also modulated by membrane-initiated effects of neuroestrogens in the short-term (within minutes). These effects are thought to depend on short-term variations in the local production of estrogens, through rapid fluctuations of the enzymatic activity of brain aromatase, the enzyme that synthesizes estradiol (E2) from testosterone. Studies in male Japanese quail have shown that a sexual interaction with a female leads to a decrease in the activity of brain aromatase within minutes. These effects occur mainly within the medial preoptic nucleus (POM), a sexually dimorphic structure of the preoptic area that plays a key role in the activation of male sexual behavior and contains the highest aromatase activity (AA) in the brain. However recent studies showed that AA does not always reflect local E2 concentration. For example, while an acute stress decreases AA in the POM, E2 concentration increases in the same conditions. Here we used in vivo microdialysis to quantify changes in E2 concentration in the male POM during sexual interactions with a female. A series of experiments conducted to validate the in vivo dialysis and RIA methods showed that (1) E2 concentration in the dialysate change linearly with the concentration of a bath containing known amounts of E2 in which the probe was placed, (2) an increase in preoptic E2 concentration is observed after retrodialysis of testosterone and (3) preoptic E2 levels also increase after a peripheral injection of E2. Together these results suggest that in vivo dialysis is a suitable method to assay E2 in the range of brain concentrations suspected to be present in physiological conditions. With this approach, we showed during two independent experiments that E2 concentrations increase in the POM during sexual interactions with a female. Birds that had their cannula placed outside the POM did not show any increase in E2 levels. The E2 increase in the POM could serve to maintain motivation during the entire sexual encounter. The decrease of AA observed ex vivo after copulation would then reflect a compensatory mechanism to restore baseline pre-copulatory conditions. [less ▲]

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See detailImproved encapsulation of proteins within calcium carbonate microparticles by means of protein-polysaccharide complexes
Ramalapa, Bathabile ULiege; Crasson, Oscar ULiege; Vandevenne, Marylène ULiege et al

Poster (2017, May 30)

The controlled delivery of proteins within calcium carbonate particles is currently widely investigated. The success of these carriers has been driven by the ionic interactions between proteins and ... [more ▼]

The controlled delivery of proteins within calcium carbonate particles is currently widely investigated. The success of these carriers has been driven by the ionic interactions between proteins and particles making the encapsulation of proteins highly dependent on the pH of reaction solutions and the isoelectric point of the protein. This poses a great limitation on the successful loading of proteins into microparticles. In this study we explored the use of polysaccharide-protein complexes to enhance the encapsulation of otherwise poorly encapsulated proteins in CaCO3 microparticles. A chitin binding domain (ChBD) was inserted on the protein β-lactamase to form a chimeric protein. A protein-polysaccharide complex was formed between the protein and hyaluronic acid (HA) owing to the intrinsic affinity of the ChBD to HA. The chimeric protein was then loaded into calcium carbonate (CaCO3) microparticles using super critical CO2 technology aided by the templating effect of HA on CaCO3. The microparticles were characterised for size, surface charge, poly-morphism and protein loading. Biochemical stability of the encapsulated β-lactamase was characterized by kinetic reaction with nitrocefin. The presence of the ChBD on the β-lactamase increased the encapsulation of the protein by 6 fold when complexed with HA. Thrombin mediated release increased the release of the protein from the microparticles within 36 hours from <25% to 87%. The protein-polysaccharide complex proved successful in enhancing the encapsulation of protein while retaining up to 81% activity and allowing controlled release of the protein by proteases. [less ▲]

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See detailObservation and simulation of ethane at 22 FTIR sites
Mahieu, Emmanuel ULiege; Franco, Bruno ULiege; Pozzer, Andrea et al

Conference (2017, May 30)

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See detailLogical tools for descriptive psychology. Set theory and foundational mereology
Leclercq, Bruno ULiege

Conference (2017, May 30)

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See detailImpact of circulation changes on the long-term trend of stratospheric hydrogen fluoride at five NDACC stations
Prignon, Maxime ULiege; Bernath, P.F.; Blumenstock, T. et al

Poster (2017, May 29)

Hydrogen fluoride is mainly produced by the photolysis of anthropogenic source gases such as the chlorofluorocarbons (CFC), the hydrochlorofluorocarbons (HCFC) and the hydrofluorocarbons (HFC). These ... [more ▼]

Hydrogen fluoride is mainly produced by the photolysis of anthropogenic source gases such as the chlorofluorocarbons (CFC), the hydrochlorofluorocarbons (HCFC) and the hydrofluorocarbons (HFC). These families of species are known for contributing to ozone depletion and/or to the greenhouse effect. It is thus essential to regulate and monitor their emissions. Despite the fact that the Montreal protocol (1987) has succeeded to reduce and then suppress the CFC emissions, HF is still increasing in the stratosphere because of ongoing emissions of the HCFC and HFC substitution products. In the framework of the recent studies demonstrating the influence of stratospheric circulation changes on the trend of long-lived tracers (e.g. hydrogen chlorine), we decided to investigate the impact of these circulation changes on HF. To achieve this objective, the rates of changes over time of HF total/partial columns at various latitudes of the globe will be determined and critically discussed. Fourier Transform Infrared data produced at five NDACC sites (Kiruna – 68°N, Jungfraujoch – 46°N, Izana – 28°N, Lauder 45°S and Arrival-heights – 78°S) and satellite data (HALOE and ACE) will be used for this study. This preliminary selection of ground-based stations allows to cover both hemispheres and our period of investigation (last two decades). Finally, in order to support our data interpretation, two SLIMCAT simulations (standard and fixed dynamics) will also be included. [less ▲]

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See detailPhysiopathologie des tendinopathies
Kaux, Jean-François ULiege

Conference (2017, May 28)

Le tendon, tissu conjonctif fibreux, mécaniquement responsable de la transmission de la force des muscles vers les os, constitue une entitédynamique qui, en fonction des contraintes, se restructure en ... [more ▼]

Le tendon, tissu conjonctif fibreux, mécaniquement responsable de la transmission de la force des muscles vers les os, constitue une entitédynamique qui, en fonction des contraintes, se restructure en permanence et, ce, grâce à diverses modifications métaboliques et mécaniques. Cetterevue décrit l’histologie, la vascularisation et l’innervation du tendon sain. De plus, la biomécanique et les réponses physiologiques tendineuses,ainsi que la physiopathologie de la tendinopathie y sont abordées. [less ▲]

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See detailActualités des traitements conservateurs des tendinopathies
Kaux, Jean-François ULiege

Conference (2017, May 28)

Les connaissances et la prise en charge des tendinopathies ont beaucoup évolué depuis ces dernières années. En effet, se substituant désormais à l’ancienne appellation « tendinite », les tendinopathies ... [more ▼]

Les connaissances et la prise en charge des tendinopathies ont beaucoup évolué depuis ces dernières années. En effet, se substituant désormais à l’ancienne appellation « tendinite », les tendinopathies sont majoritairement décrites selon le modèle de continuum établi par Cook et Purdam. La compréhension de la physiopathologie de ces lésions a permis l’émergence de nombreux traitements dans le but d’obtenir une récupération optimale et une limitation des récidives. L’objectif de cet article est de faire une revue de l’actualité thérapeutique des tendinopathies. [less ▲]

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See detailMultifunctional poly(ionic liquid)s: from synthesis to applications in energy and environment
Detrembleur, Christophe ULiege; Patil, Nagaraj ULiege; Debuigne, Antoine ULiege et al

Conference (2017, May 24)

Poly(ionic liquid)s (PILs) are a subclass of polyelectrolytes that gained an enabling role in many fields of polymer chemistry and material science. PILs combine the unique properties of ionic liquids ... [more ▼]

Poly(ionic liquid)s (PILs) are a subclass of polyelectrolytes that gained an enabling role in many fields of polymer chemistry and material science. PILs combine the unique properties of ionic liquids with the flexibility and properties of macromolecules, and provide novel attractive functions. Recently, the precision design of novel PILs by controlled/living polymerization (CLP) techniques was intensively searched for developing emerging applications. This talk will first discuss recent routes for the precision synthesis of all vinyl-imidazolium based (co)polymers in water or in organic media under non-demanding experimental conditions. We will then describe the preparation of innovative redox and surface active PILs, and show the potential of these PILs in battery applications and for multifunctional coatings. More specifically, we will show how macromolecular engineering can be exploited for designing innovative polymer cathodes for ultra-high performance Li storage with unprecedented performances (high capacities and ultra-long life-span over more than 3000 cycles at an extreme current-rate). This innovative and effective molecular design for polymer cathodes opens up new horizons in developing an economical and environmentally benign platform for large-scalable fabrication of high performance batteries. [less ▲]

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See detailStreptomyces from Moonmilk, an Untapped Source of New Bioactive Compounds
Martinet, Loïc ULiege; Maciejewska, Marta; Adam, Delphine ULiege et al

Poster (2017, May 24)

Moonmilk speleothems of limestone caves host a rich microbiome, among which Actinobacteria represent one of the most abundant phyla. Ancient medical texts reported that moonmilk had therapeutical ... [more ▼]

Moonmilk speleothems of limestone caves host a rich microbiome, among which Actinobacteria represent one of the most abundant phyla. Ancient medical texts reported that moonmilk had therapeutical properties, thereby suggesting that its filamentous endemic actinobacterial population might be a source of natural products useful in human treatment. In this work, a screening approach was undertaken in order to isolate cultivable Actinobacteria from moonmilk of the Grotte des Collemboles in Belgium, to evaluate their taxonomic profile, and to assess their potential in biosynthesis of antimicrobials. Phylogenetic analysis revealed that all 78 isolates were exclusively affiliated to the genus Streptomyces and clustered into 31 distinct phylotypes displaying various pigmentation patterns and morphological features. Phylotype representatives were tested for antibacterial and antifungal activities and their genomes were mined for secondary metabolite biosynthetic genes coding for non-ribosomal peptide synthetases (NRPSs), and polyketide synthases (PKS). The moonmilk Streptomyces collection was found to display strong inhibitory activities against a wide range of reference organisms, as 94, 71, and 94% of the isolates inhibited or impaired the growth of Gram-positive, Gram-negative bacteria, and fungi, respectively. Interestingly, 90% of the cave strains induced strong growth suppression against the multi-drug resistant Rasamsonia argillacea, a causative agent of invasive mycosis in cystic fibrosis and chronic granulomatous diseases. We are currently identifying molecules responsible for the observed antimicrobial activities which, next to few known bioactive compounds, also reveals many active compounds with molecular masses that do not correspond to known antibiotic deposited in web biomolecules databases such as KNapSAcK, Pubchem, Chemspider. The challenge is to increase the production yields of these unknown compounds, and purify them to further characterize their structure by NMR. Overall, our work supports the common belief that moonmilk might effectively treat various infectious diseases thanks to the presence of a highly diverse population of prolific antimicrobial producing Streptomyces, and thus may indeed constitute a promising reservoir of potentially novel active natural compounds. [less ▲]

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See detailOral communication: Brassica napus L. plantlets affected during in vitro growth by the presence of epoxiconazole.
Durenne, Bastien ULiege; Blondel, Alodie; Ducat, Nathalie et al

Conference (2017, May 24)

Detailed reference viewed: 39 (6 ULiège)
See detailTh17 cells impact on xenogeneic graft-versus-host disease
Delens, Loïc ULiege; SERVAIS, Sophie ULiege; Ehx, Grégory ULiege et al

Poster (2017, May 24)

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See detailCe que devait encore révéler le site de la Schola del Traiano à Ostia Antica
Morard, Thomas ULiege

Conference (2017, May 24)

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See detailPolyphosphoesters: new trends in synthesis and drug delivery applications
Jérôme, Christine ULiege

Conference (2017, May 24)

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Peer Reviewed
See detailTime, preference and intensity: A contrastive study of rather (than) and eerder (dan)
Ghesquière, Lobke; Brems, Lieselotte ULiege

Conference (2017, May 24)

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See detailAn anticancer molecule stemming from a plant root produced in a bioreactor
Vassaux, Antoine; Tarayre, Cédric ULiege; Delvigne, Frank ULiege et al

Poster (2017, May 24)

Secondary metabolites produced by plants or their symbionts have already shown specific properties: anticancer, anti-inflammatory, antibacterial, antifungal effects, etc. Astin C is a non-ribosomal ... [more ▼]

Secondary metabolites produced by plants or their symbionts have already shown specific properties: anticancer, anti-inflammatory, antibacterial, antifungal effects, etc. Astin C is a non-ribosomal peptide (secondary metabolite) produced by the fungus Villosirosea asteris, endosymbiont of the medicinal plant Aster tataricus, which has shown an interesting anticancer activity. The current challenge is the production of the molecule on a large scale and in higher quantities, either from the original fungus through fermentation technologies, or by a heterologous yeast strain having integrated the genes involved in the astin C biosynthesis pathway. The purpose of this workshop is to highlight the implementation possibilities of a strain producing a metabolite of interest. [less ▲]

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See detailCorrection de questions à réponses ouvertes: le logiciel SQORE
Crahay, Vinciane ULiege; Bonnet, Pierre ULiege

Conference (2017, May 23)

Detailed reference viewed: 51 (8 ULiège)
See detailStudy of volatile organic compounds active against barley pathogens
De Clerck, Caroline ULiege; Kaddes, Amine ULiege; Fiers, Marie et al

Conference (2017, May 23)

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See detailÉdition et étude de Gerard du Frattre, compilation épique du XVIe siècle
Lambert, Adélaïde ULiege

Poster (2017, May 23)

Présentation du projet de thèse de doctorat.

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See detailPrecision synthesis and characterization of novel functional polymers
Scholten, Philip ULiege; Debuigne, Antoine ULiege; Demarteau, Jérémy ULiege et al

Poster (2017, May 23)

Among controlled radical polymerisation techniques, cobalt-mediated radical polymerisation (CMRP) has proven to be a valuable alternative in polymerising unreactive and unconjugated monomers of many ... [more ▼]

Among controlled radical polymerisation techniques, cobalt-mediated radical polymerisation (CMRP) has proven to be a valuable alternative in polymerising unreactive and unconjugated monomers of many different monomer classes under mild conditions, including α-olefins. In a reversible deactivation mechanism, a cobalt complex reversibly traps the active growing chains and converts them into dormant species, avoiding side reactions and allowing for a controlled polymerisation. A fine control over the architecture is possible and allows to synthesise a large diversity of unprecedented block and alternating copolymers. Furthermore, functionalisation of the α- and ω-chain ends is now also possible. In this poster, the polymerization of different vinyl monomers using CMRP has been investigated to design highly functional materials under mild experimental conditions. The copolymerisation behaviour of these novel monomers was examined, and the structure and thermal properties of the new copolymers were investigated. [less ▲]

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See detailA surprising and dramatic neuroendocrine-immune phenotype of mice deficient in Growth Hormone-Releasing Hormone (GHRH)
Farhat, Khalil; Bodart, Gwennaëlle ULiege; RENARD, Jeanne de Chantal ULiege et al

Poster (2017, May 23)

In the framework of close interactions between the immune and neuroendocrine systems, Growth Hormone (GH) has been proposed to exert significant effects on the immune system, but there is not yet a ... [more ▼]

In the framework of close interactions between the immune and neuroendocrine systems, Growth Hormone (GH) has been proposed to exert significant effects on the immune system, but there is not yet a consensus about GH immunomodulatory properties. These studies investigated the immune and anti-infectious response of dwarf Ghrh-/- mice presenting a severe deficiency of the GHRH/GH/IGF-1 axis. In basal conditions, thymic parameters and T-cell responses of Ghrh-/- mice were not severely affected but a constant B-cell lymphopaenia was observed. Thus, we investigated vaccine and anti-infectious responses of Ghrh-/- mice toward Streptococcus pneumonia, a B-dependent pathogen, Ghrh-/- mice were unable to trigger production of specific IgM and IgG against serotype 1 pneumococcal polysaccharide (PPS) after vaccination with either native PPS (Pnx23) or protein-PPS conjugate (Prev-13) vaccines. These vaccines both include the serotype 1 (our S.pneumoniae strain) and provide an effective protection in mice. A short GH supplementation to Ghrh-/- mice (1 daily injection of 1 mg/kg GH for 4 weeks) restored IgM and IgG response to Pnx23 vaccine but not to Prev-13. This suggests that GH could exert distinct impacts upon spenic areas. Furthermore, after intranasal instillation of a non-lethal dose (defined by the full clearance by WT C57BL/6 mice after 24h) of serotype 1 S.pneumoniae, Ghrh-/- mice exhibited a dramatic susceptibility. This was proved by a marked time-dependent increase in pulmonary bacterial, a septicemia already 24h after infection and a survival limit of 72h. We also observed a dramatic decrease in lung B- and T-cell populations and an increase in proportion of inflammatory macrophages. By contrast, wild-type and heterozygote mice completely cleared S.pneumoniae infection after 24h. In conclusion, our data show without ambiguity that the somatotrope GHRH/GH/IGF-1 axis plays an important and unsuspected role in defense against S.Pneumoniae. [less ▲]

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See detailDesign of polyphosphoester-based drug delivery systems by efficient thiol-ene reaction
Riva, Raphaël ULiege; Vanslambrouck, Stéphanie; Ergül, Zeynep ULiege et al

Poster (2017, May 23)

Thanks to their biocompatibility, biodegradability and their structure similar to natural biomacromolecules, polyphosphoesters (PPE) are appealing polymers for biomedical applications. In contrast to ... [more ▼]

Thanks to their biocompatibility, biodegradability and their structure similar to natural biomacromolecules, polyphosphoesters (PPE) are appealing polymers for biomedical applications. In contrast to polyesters, PPE properties and functionality are easily tuned via the chemical nature of the lateral chains. To enhance the drug loading capacity of PPE-based micelles used as carriers for the delivery of poorly soluble drugs, an efficient strategy to increase the lipophilicity of the PPE block of polyethylene oxide (PEO)-b-PPE amphiphilic copolymers has been investigated. A PEO-b-PPE copolymer bearing pendant vinyl groups along the PPE block was synthesized and then modified by thiol-ene click reaction with thiols bearing either a long linear alkyl chain (dodecyl) or a tocopherol moiety. Ketoconazole was used as model for hydrophobic drugs. Comparison of the loading contents and release profiles with PEO-b-PPE bearing shorter pendant groups is presented evidencing the key role of the structure of the pendant group on the PPE backbone. Finally, the low cytotoxicity of these novel PEO-b-PPE copolymers was also demonstrated. The tocopherol derivative was evidenced as particularly promising for drug delivery systems. [less ▲]

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