References of "Scientific journals => Other"
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See detailThe mechanisms of chronic ischemic mitral regurgitation
RADERMECKER, Marc ULg; LANCELLOTTI, Patrizio ULg

in Annals of Thoracic Surgery (2007), 83(5), 1919-20

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See detailThermoplastic patient fixation: influence on chest wall and target motion during radiotherapy of lung cancer.
Cselik, Zolt; Horvath, Akos; Repa, Imre et al

in Strahlentherapie und Onkologie (2007), 183(5), 271-8

Several methods have been developed to reduce tumor motions and patient movements during radiotherapy of lung cancer. In this study, a multislice CT-based analysis was performed to examine the effect of a ... [more ▼]

Several methods have been developed to reduce tumor motions and patient movements during radiotherapy of lung cancer. In this study, a multislice CT-based analysis was performed to examine the effect of a thermoplastic patient immobilization system on the chest wall and tumor motions. Ten patients with stage II-IV lung cancer were enrolled into the study. According to tumor localization, five patients had peripheral, and five patients central lung cancer (T2-T4). In total, six series of measurements were made with a multislice CT scanner, both with and without mask fixation, in normal breathing, at maximal tidal volume inhalation, and at maximal tidal volume exhalation. Movements of chest wall, diaphragm and tumor, with and without mask, under different breathing conditions were registered. With the use of the immobilization system, no significant difference was found in diaphragmatic movements (mean deviation of diaphragm: 41.7-40.5 mm to the right, and 40.5-36.8 mm to the left side) and in tumor motions (mean deviation of tumor: 15.3-12.4 mm in craniocaudal, and 11.5-8.8 mm in posterolateral direction, mean medial deviation: 4.6-4.1 mm, mean lateral deviation: 7.2-5 mm). Significant differences were observed concerning tumor motions in anteroposterior direction (mean: 8.9-6.3 mm) and transverse chest movements in anteroposterior direction. Besides the advantage of optimal patient positioning, the movements of the bony chest wall can be considerably reduced by using the immobilization system. However, this fixation system has limitations concerning its suitability for minimizing tumor motions. [less ▲]

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See detailMetallo-beta-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues
Cornaglia, G.; Akova, M.; Amicosante, G. et al

in International Journal of Antimicrobial Agents (2007), 29(4), 380-388

The rapid spread of acquired metallo-beta-lactamases (MBLs) among major Gram-negative pathogens is a matter of particular concern worldwide and primarily in Europe, one of first continents where the ... [more ▼]

The rapid spread of acquired metallo-beta-lactamases (MBLs) among major Gram-negative pathogens is a matter of particular concern worldwide and primarily in Europe, one of first continents where the emergence of acquired MBLs has been reported and possibly the geographical area where the increasing diversity of these enzymes and the number of bacterial species affected are most impressive. This spread has not been paralleled by accuracy/standardisation of detection methods, completeness of epidemiological knowledge or a clear understanding of what MBL production entails in terms of clinical impact, hospital infection control and antimicrobial chemotherapy. A number of European experts in the field met to review the current knowledge on this phenomenon, to point out open issues and to reinforce and relate to one another the existing activities set forth by research institutes, scientific societies and European Union-driven networks. (c) 2006 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved. [less ▲]

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See detailPeter Ladislaw Hammer (1936-2006)
Boros, Endre; Crama, Yves ULg; Simeone, Bruno

in 4OR : Quarterly Journal of the Belgian, French and Italian Operations Research Societies (2007), 5(1), 1-4

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See detailSteps for the implementation and validationof tight glucose control
Preiser, Jean-Charles ULg; Devos, P.

in Intensive Care Medicine (2007), 33(4), 570-571

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See detail36th International Liege Colloquium on Ocean Dynamics - Liege, Belgium, 3-7 May, 2004 - Marine environmental monitoring and prediction - Preface
Desaubies, Yves; Rixen, Michel; Beckers, Jean-Marie ULg

in Journal of Marine Systems (2007), 65(1-4), 1-2

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See detailFaecal bacterial molecular profiles of Crohn’s disease patients differ from their healthy relatives and matched healthy controls.
Joossens, M.; De Preter, V.; Vanhoutte, T. et al

in Gut (2007), 56(Suppl III), 5

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See detailEditorial
Franssen, Jean-Marc ULg; Vila Real, Paulo

in Fire Safety Journal (2007), 42(6-7, SEP-OCT), 407-407

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See detailSpecial issue: Respiratory viruses of domestic animals - Foreword
Thiry, Etienne ULg

in Veterinary Research (2007), 38(2, FEB-MAR), 151-151

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See detailGenetic markers and the risk of complicated disease behaviour in Crohn's disease patients
Henckaerts, L.; Verstreken, I.; Van Steen, Kristel ULg et al

in Gastroenterology (2007), 132(4), 17-18

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See detailPet ownership in eight European birth cohorts - results of a GA(2)LEN initiative
Roll, S.; Keil, T.; Eller, E. et al

in Allergy (2007), 62

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See detailMucosal gene expression profiling to predict response to infliximab in patients with ulcerative colitis
Arijs, I.; Van Lommel, L.; Van Steen, Kristel ULg et al

in Gut (2007), 56(Suppl III), 19

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See detailGene expression profiling to predict the response of infliximab in patients with UC
Arijs, I.; Van Lommel, L.; Van Steen, Kristel ULg et al

in Journal of Crohn’s and Colitis [=JCC] (2007), 1(1), 34

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See detailDoes a patient's self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer? (vol 42, pg 42, 2006)
Efficace, Fabio; Bottomley, Andrew; Coens, Corneel et al

in European Journal of Cancer (2007), 43(3), 633-633

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See detailFaecal bacterial DGGE profiles of Crohn’s disease patients are different from those of their healthy first degree relatives and matched healthy controls
Joossens, M.; Vanhoutte, T.; De Preter, V. et al

in Acta Gastro-Enterologica Belgica (2007)

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See detailFaecal bacterial dgge profiles of Crohn's disease patients are different from those of their healthy first degree relatives and matched healthy controls
Joossens, Marie; Vanhoutte, Tom; De preter, Vicky et al

in Journal of Crohn’s and Colitis [=JCC] (2007), 1(1), 55

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See detailGenetic markers and the risk of complicated disease behaviour in Crohn's disease patients
Henckaerts, Liesbet; Verstreken, Isabel; Van Steen, Kristel ULg et al

in Journal of Crohn’s and Colitis [=JCC] (2007), 1(1), 41-42

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See detailGenetic markers and the risk of complicated disease behaviour in Crohn’s disease patients
Henckaerts, L.; Verstreken, I.; Van Steen, Kristel ULg et al

in Gut (2007)

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See detailMixed IBD families: A distinct entity within IBD
Pierik, M.; Van Steen, Kristel ULg; Joossens, M. et al

in Gastroenterology (2007), 132(4), 450-450

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See detailGene expression profiling to predict the response of infliximab in patients with UC
Arijs, Ingrid; Van lommel, Leertje; Van Steen, Kristel ULg et al

in Gastroenterology (2007), 132(4), 174-174

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See detailDu droit des consommateurs de prendre part aux procédures de sanctions des infractions au droit de la concurrence
Sibony, Anne-Lise ULg

in Revue Lamy de la Concurrence (2007), (11), 789

In the reported judgement, CFI states that any client of a company suspected of having violated competition rules has a legitimate interest to apply to the Commission for a decision establishing an ... [more ▼]

In the reported judgement, CFI states that any client of a company suspected of having violated competition rules has a legitimate interest to apply to the Commission for a decision establishing an infringement. [less ▲]

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See detailEditorial Report 2006
Denoël, Mathieu ULg

in Amphibia-Reptilia (2007), 28(3), 455-456

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See detailFaecal bacterial dgge profiles of Crohn's disease patients are different from those of their healthy first degree relatives and matched healthy controls
Joossens, M.; Vanhoutte, T.; De Preter, V. et al

in Gastroenterology (2007), 132(4), 704-704

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See detailL'information du patient lombalgique.
Marty, M.; Henrotin, Yves ULg

in Rhumatologie Pratique (2007), 242

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See detailThe bone mineralization density distribution as a fingerprint of the mineralization process
Ruffoni, Davide ULg; Fratzl, P.; Roschger, P. et al

in BONE (2007), 40(5), 1308-1319

The inhomogeneous mineral content and its topographical distribution on a microscopic scale are major determinants of the mechanical quality of trabecular bone. The kinetics of bone tissue deposition and ... [more ▼]

The inhomogeneous mineral content and its topographical distribution on a microscopic scale are major determinants of the mechanical quality of trabecular bone. The kinetics of bone tissue deposition and resorption together with the kinetics of the mineralization process determine the distribution of mineral in the tissue. The heterogeneity of the mineral content is described by the well-established bone mineralization density distribution (BMDD), which is experimentally accessible, e.g., using quantitative electron backscattering imaging (qBEI). In the present work, we demonstrate that the shape of the BMDD histogram of trabecular bone reflects directly the mineralization kinetics. Based on the experimental BMDD data of trabecular bone from healthy human adults and using a mathematical model for the remodeling and the mineralization process, the following main results were obtained. The peaked BMDD reflects necessarily a two-phase mineralization process with a fast primary phase and a slow secondary phase where the corresponding time constants differ three orders of magnitude. The obtained mineralization law, which describes the increase in the mineral content in a bone packet as a function of time, provides information not only about the initial mineralization surge, but also about the slow increase afterwards on the time scale of years. In addition to the mineralization kinetics the turnover rate of the remodeling process has a strong influence on the peak position and the shape of the BMDD. The described theoretical framework opens new possibilities for an analysis of experimentally measured BMDDs with respect to changes caused by diseases or treatments. It a] lows addressing whether changes in the BMDD have to be attributed to a variation in the turnover rate which consequently affects the density distribution or to a primary disorder in the mineralization process most likely reflecting alterations of the organic matrix. This is of important clinical interest because it helps to find therapeutic approaches directly targeting the primary etiological defects to correct the patients' BMDD towards normal BMDD. (c) 2007 Elsevier Inc. All rights reserved. [less ▲]

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See detailMechanical response and conformational changes of alpha-actinin domains during unfolding: a molecular dynamics study
Soncini, Monica; Vesentini, Simone; Ruffoni, Davide ULg et al

in BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2007), 6(6), 399-407

Alpha-actinin is a cytoskeleton-binding protein involved in the assembly and regulation of the actin filaments. In this work molecular dynamics method was applied to investigate the mechanical behaviour ... [more ▼]

Alpha-actinin is a cytoskeleton-binding protein involved in the assembly and regulation of the actin filaments. In this work molecular dynamics method was applied to investigate the mechanical behaviour of the human skeletal muscle a-actinin. Five configurations were unfolded at an elongation speed of 0.1 nm/ps in order to investigate the conformational changes occurring during the extension process. Moreover, a sensitivity analysis at different velocities was performed for one of the R2-R3 spectrin-like repeat configuration extracted in order to evaluate the effect of the pulling speed on the mechanical behaviour of the molecule. Two different behaviours were recognized with respect to the pulling speed. In particular, at speed higher than 0.025nm/ps a continuous rearrangement without evident force peaks was obtained, on the contrary at lower speed evident peaks in the range 500-750 pN were detected. R3 repeat resulted more stable than R2 during mechanical unfolding, due to the lower hydrophobic surface available to the solvent. The characterization of the R2-R3 units can be useful for the development of cytoskeleton network models based on stiffness values obtained by analyses performed at the molecular level. [less ▲]

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See detailPreface: A tribute to Muriel Fairon-Demaret
Gerrienne, Philippe ULg

in Review of Palaeobotany and Palynology (2006), 142(3-4), 61-61

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See detailGlycémie délocalisée: Entretien avec le Dr Etienne CAVALIER
Cavalier, Etienne ULg

in Biotribune Magazine (2006), 19(1), 33

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See detailMethylene blue: An old-timer or a compound ready for revival?
Donati, A.; Preiser, Jean-Charles ULg

in Critical Care Medicine (2006), 34(11), 2862-2863

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See detail20 years of NF-kappa B
Chariot, Alain ULg

in Biochemical Pharmacology (2006), 72(9), 1051-1053

We are celebrating this year 20 years of research dedicated to the transcription factor NF-kB. From 1986, the year of its initial identification as a DNA-binding activity for the enhancer of the ... [more ▼]

We are celebrating this year 20 years of research dedicated to the transcription factor NF-kB. From 1986, the year of its initial identification as a DNA-binding activity for the enhancer of the immunoglobulin k light-chain in activated B cells by David Baltimore and colleagues [1] to 2006, almost 20000 papers related to this transcription factor were published, which means three reports per day. This amazing amount of data generated over the years and throughout the world reflects the critical roles played by NF-kB in biology. It is indeed increasingly difficult to find circumstances where NF-kB is not involved at one point. One reason is due to the amazing amount of signals that can activate NF-kB. They include bacterial, viral and fungal products but also inflammatory cytokines, oxidative stress and therapeutically used drugs (as reviewed by Y. Habraken and J. Piette in this issue) and are listed in Tom Gilmore’s website (www.nf-kb.org) (Boston University). Another reason is due to the functional kB sites found in about one hundred genes [2]. These numerous NF-kB target genes play critical roles in cell survival and proliferation, as well as in innate and adaptive immunity, which reflects the essential role of this transcription factor in physiology and diseases. [less ▲]

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See detailCommentary: osteoarthritis of the knee and glucosamine
Altman, R. D.; Abramson, S.; Bruyère, Olivier ULg et al

in Osteoarthritis and Cartilage (2006), 14(10), 963-966

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See detailChimerism and outcomes after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning
Baron, Frédéric ULg; Sandmaier, B. M.

in Leukemia (2006), 20(10), 1690-1700

Allogeneic hematopoietic cell transplantation ( HCT) following nonmyeloablative conditioning has been extensively evaluated in patients with hematologic malignancies who are ineligible for conventional ... [more ▼]

Allogeneic hematopoietic cell transplantation ( HCT) following nonmyeloablative conditioning has been extensively evaluated in patients with hematologic malignancies who are ineligible for conventional HCT because of age or medical comorbidities. Nonmyeloablative regimens have led to an initial state of mixed hematopoietic chimerism defined as coexistence of donor- and host-derived hematopoiesis. While nonmyeloablative regimens have been associated with reduced regimen-related toxicities in comparison with conventional myeloablative conditioning, graft rejection, graft-versus-host disease ( GVHD), and disease progression have remained significant challenges. In this article, after briefly introducing current techniques for chimerism assessment, we describe factors affecting donor chimerism levels after nonmyeloablative conditioning, and then review data suggesting that chimerism assessment early after HCT might help identify patients at risk for graft rejection, GVHD and relapse/progression. Finally, we discuss how these observations have opened the way to further research protocols evaluating manipulation of postgrafting immunosuppression, and/or infusion of donor immune cells. [less ▲]

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See detailTowards a definition of intractable headache for use in clinical practice and trials
Goadsby, P. J.; Schoenen, Jean ULg; Ferrari, M. D. et al

in Cephalalgia : An International Journal of Headache (2006), 26(9), 1168-1170

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See detailThe ideal arena for intensive and continuous questioning
Preiser, Jean-Charles ULg

in Current Opinion in Critical Care (2006), 12(4), 289-289

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See detailTracking the recovery of consciousness from coma
Laureys, Steven ULg; Boly, Mélanie ULg; Maquet, Pierre ULg

in Journal of Clinical Investigation (2006), 116(7), 1823-1825

Predicting the chances of recovery of consciousness and communication in patients who survive their coma but transit in a vegetative state or minimally conscious state (MCS) remains a major challenge for ... [more ▼]

Predicting the chances of recovery of consciousness and communication in patients who survive their coma but transit in a vegetative state or minimally conscious state (MCS) remains a major challenge for their medical caregivers. Very few studies have examined the slow neuronal changes underlying functional recovery of consciousness from severe chronic brain damage. A case study in this issue of the JCI reports an extraordinary recovery of functional verbal communication and motor function in a patient who remained in MCS for 19 years (see the related article beginning on page 2005). Diffusion tensor MRI showed increased fractional anisotropy (assumed to reflect myelinated fiber density) in posteromedial cortices, encompassing cuneus and precuneus. These same areas showed increased glucose metabolism as studied by PET scanning, likely reflecting the neuronal regrowth paralleling the patient's clinical recovery. This case shows that old dogmas need to be oppugned, as recovery with meaningful reduction in disability continued in this case for nearly 2 decades after extremely severe traumatic brain injury. [less ▲]

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See detailIs the neutrophil a worthy target in severe asthma and chronic obstructive pulmonary disease?
Louis, Renaud ULg; Djukanovic, R.

in Clinical & Experimental Allergy : Journal of the British Society for Allergy & Clinical Immunology (2006), 36(5), 563-567

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See detailRecommendations for an update of the current (2001) regulatory requirements for registration of drugs to be used in the treatment of osteoporosis in postmenopausal women and in men
Reginster, Jean-Yves ULg; Abadie, Eric ULg; Delmas, P. et al

in Osteoporosis International (2006), 17(1), 1-7

Recent advances in the understanding of the epidemiology of osteoporosis suggest that certain parts of the current European guidelines for the registration of drugs in osteoporosis might be no longer ... [more ▼]

Recent advances in the understanding of the epidemiology of osteoporosis suggest that certain parts of the current European guidelines for the registration of drugs in osteoporosis might be no longer substantiated. The object of this review is to provide the European regulatory authorities with an evidence-based working document providing suggestions for the revision of the "Note for guidance for the approval of drugs to be used in postmenopausal osteoporosis" (CPMP/EWP/552/95). Following an extensive review of the literature (1990-2004), the Group for the Respect of Ethics and Excellence in Science (GREES) organized a workshop including European regulators, academic scientists and representatives of the pharmaceutical industry. The outcomes of this meeting reflect the personal views of those who attended and should not, in any case, be seen as an official position paper of any regulatory agency. The group identified a certain number of points that deserve discussion. They mainly relate to the nature of the indication being granted to new chemical entities (treatment of osteoporosis in women at high risk of fracture instead of prevention and treatment of osteoporosis), the requirements of showing an anti-fracture efficacy on all or on major nonvertebral fractures (instead of the hip), the duration of pivotal trials (2 years instead of 3) and the possibility of considering bridging studies for new routes of administration, new doses or new regimens of previously approved drugs. The group also recommends that an indication could be granted for the treatment of osteoporosis in males on the basis of a placebo-controlled study, with bone mineral density changes after 1 year as the primary endpoint, for medications approved in the treatment of osteoporosis in women at high risk of fractures. [less ▲]

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See detailAndrogen metabolism and the activation of male sexual behavior: It's more complicated than you think!
Ball, G. F.; Balthazart, Jacques ULg

in Hormones & Behavior (2006), 49(1), 1-3

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See detailForeword - Transport protocols for next generation networks
Pham, Congduc; Leduc, Guy ULg

in Annales des Télécommunications = Annals of Telecommunications (2006), 61(1-2, JAN-FEB), 2-4

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See detailVertebrate origins: does the tunic make the man?
Delsuc, Frédéric; Baurain, Denis ULg; Philippe, Hervé

in Medecine Sciences : M/S (2006), 22(8-9, AUG-SEP), 688-690

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See detail"Prose" - direction du "Dossier américain" (116 pages)
Delville, Michel ULg

in Formes Poétiques Contemporaines (2006), 4

Direction du dossier "dossier américain" du vol. 4 de la revue FPC (2006): pp. 213-328

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See detailMethods to study protein aggregation and amyloid formation
Dumoulin, Mireille ULg; Bader, R.

in Protein & Peptide Letters (2006), 13

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See detailEditorial Report 2005
Denoël, Mathieu ULg

in Amphibia-Reptilia (2006), 27(3), 479

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See detailNutraceuticals in the management of osteoarthritis - facts and Senses
Henrotin, Yves ULg

in European Companion Animal Health (2006)

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See detailPourquoi et comment informer le patient lombalgique ?
Bazin, T.; Henrotin, Yves ULg; Cedraschi, C. et al

in Réflexions rhumatologiques (2006), 10(3), 32-35

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See detailChronique de la 60ème Session de la Société Internationale Fernand de Visscher à Komotini (26-30 Septembre 2006)
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité (2006), LIII

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See detailDegenerative osteoarthropathy in horses: pathogeny and diagnostic
Lejeune, Jean-Philippe ULg; Schneider, Nicole ULg; Henrotin, Yves ULg et al

in Annales de Médecine Vétérinaire (2006), 150(3), 173-192

This work presents some important features of the normal articular structures and a definition of the degenerative osteo-arthropathy that points the involvement of all the joint structures. The pathogeny ... [more ▼]

This work presents some important features of the normal articular structures and a definition of the degenerative osteo-arthropathy that points the involvement of all the joint structures. The pathogeny of the pathology is tackled by the potential risk factors and by the cartilage-cartilage, synovium-cartilage and bone-cartilage cycles that lay particular emphasis on the interaction between the different joint structures. The diagnostic tools of the degenerative osteo-arthropathy like the conventional or recent imaging techniques (magnetic resonance imaging, scintigraphy and tomography) and the biomarkers of the cartilage and bone metabolisms are listed. The pathogeny of the degenerative osteo-arthropathy is complex and involves different factors. This disease is characterised by an imbalance between the anabolic and catabolic processes of the cartilage metabolism. Inflammation is also present and lead to the clinical signs. The synovitis, the liberation of degradation mediators, the mechanical stresses and/or the subchondral bone are part of the pathogeny at different degrees. The development of recent imaging techniques and the biomarkers of the cartilage and bone metabolisms allow the precise description of the lesions and give some additional information on the pathogeny of the osteo-arthropathy. These recent techniques raise new questions and allow the in-depth analysis of the study of the osteo-arthropathy. [less ▲]

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See detailEditorial du numéro consacré aux compétences
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2006), 21-22

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See detailTraduction française (et introduction): Rudolf Hermann Lotze, « Le monde des Idées » (Logik. Drittes Buch. Vom Erkennen, Ch. II)
Dewalque, Arnaud ULg

in Philosophie (2006), 91

L’interprétation de la théorie platonicienne des Idées défendue par Hermann Lotze dans le troisième livre de sa "Logik" de 1874 consiste à comprendre la « théorie des deux mondes » à partir de la ... [more ▼]

L’interprétation de la théorie platonicienne des Idées défendue par Hermann Lotze dans le troisième livre de sa "Logik" de 1874 consiste à comprendre la « théorie des deux mondes » à partir de la distinction, à tous égards fondamentale, entre d’une part la validité des vérités, et d’autre part l’être spatio-temporel des choses ou celui, temporel, des représentations. En posant la question de la vérité, la logique n’a affaire ni à des choses, ni à des représentations. Cette thèse a conféré au chapitre sur le « monde des Idées » une signification critique de première importance et en a fait, du même coup, une référence privilégiée pour les partisans d’un antinaturalisme et d’un antipsychologisme logique. [less ▲]

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See detailTable ronde : "Le Normal et le Pathologique"
Fournier, Emmanuel; Jabre, JF; Labarre-Vila, Annick et al

in Neurophysiologie Clinique = Clinical Neurophysiology (2006)

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See detailIs it time for implementation of tight glycaemia control by intensive insulin therapy in every ICU?
Devos, P.; Preiser, Jean-Charles ULg

in Critical Care (2006), 10(2), 130

The second study on tight glycaemia control by intensive insulin therapy (IIT) confirmed in medical intensive care unit patients the decrease in hospital mortality reported by the same team in the first ... [more ▼]

The second study on tight glycaemia control by intensive insulin therapy (IIT) confirmed in medical intensive care unit patients the decrease in hospital mortality reported by the same team in the first IIT trial in surgical patients. However, methodological concerns, the high rate of hypoglycaemia in spite of the infusion of large doses of parenteral glucose and the frequent use of steroids presently preclude considering these results as recommendations in other intensive care units, but rather argue for the need for large-scale assessment of the IIT approach by multi-centre studies to confirm the efficacy and safety of this therapeutic modality. [less ▲]

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See detailChondroprotective/structure-modifying drugs: a neverending story
Henrotin, Yves ULg

in Reumatissimo (2006), 58

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See detailThe syndrome of transient headache with neurological deficits and CSF lymphocytosis (HaNDL): electrophysiological findings suggesting a migrainous pathophysiology
Fumal, Arnaud ULg; Vandenheede, Michel; Coppola, Giunluca et al

in Cephalalgia : An International Journal of Headache (2005), 25(9), 754-758

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See detailChronic ischaemic mitral regurgitation: exercise testing reveals its dynamic component
LANCELLOTTI, Patrizio ULg; PIERARD, Luc ULg

in European Heart Journal (2005), 26(18), 1816-1817

This editorial refers to 'Exercise-induced changes in mitral regurgitation in patients with prior myocardial infarction and left ventricular dysfunction: relation to mitral deformation and left ... [more ▼]

This editorial refers to 'Exercise-induced changes in mitral regurgitation in patients with prior myocardial infarction and left ventricular dysfunction: relation to mitral deformation and left ventricular function and shape'(dagger) by V. Giga et al., on page 1860. [less ▲]

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See detailCurrent status of brain imaging in sleep medicine
Maquet, Pierre ULg

in Sleep Medicine Reviews (2005), 9(3), 155-156

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See detailDistribution of F-18 fluorodeoxyglucose (F-18 FDG) in abdominal aortic aneurysm: High accumulation in macrophages seen on PET Imaging and immunohistology
Defawe, O. D.; Hustinx, Roland ULg; Defraigne, Jean-Olivier ULg et al

in Clinical Nuclear Medicine (2005), 30(5), 340-341

A 68-year-old man was hospitalized for unstable angina and underwent emergency coronary artery bypass surgery. During the operation, a pulsatile large abdominal aortic aneurysm (AAA) was discovered. To ... [more ▼]

A 68-year-old man was hospitalized for unstable angina and underwent emergency coronary artery bypass surgery. During the operation, a pulsatile large abdominal aortic aneurysm (AAA) was discovered. To define the optimal treatment of the abdominal aneurysm, after bypass surgery, CT scans and positron emission tomography (PET) were performed, as we routinely do. PET imaging combined with immunohistologic examination showed a region of increased F-18 FDG uptake corresponding to an inflammatory infiltrate in the aortic wall in contrast to the thrombus in the aneurysm (devoid of inflammatory cells). The luminal area showed midlevel F-18 FDG uptake corresponding to circulating mediators. [less ▲]

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See detailHeme oxygenase: A new piece in the glutamine puzzle
Preiser, Jean-Charles ULg; Coeffier, M.

in Critical Care Medicine (2005), 33(2), 457-458

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See detailAnémie et risque cardiovasculaire chez l'insuffisant rénal
Krzesinski, Jean-Marie ULg

in Brochure "Roche" Ericabell (2005)

Le patient souffrant d'insuffisance rénale terminale est exposé à une mortalité de 5 à 30 fois supérieure à celle de la population générale à âge identique. Au moins 50% de cette surmortalité sont dus à ... [more ▼]

Le patient souffrant d'insuffisance rénale terminale est exposé à une mortalité de 5 à 30 fois supérieure à celle de la population générale à âge identique. Au moins 50% de cette surmortalité sont dus à des complications cardiovasculaires. Des signes de coronaropathie et d'insuffisance cardiaque sont déjà présents chez 40% de patients au début des traitements par dialyse. Ce risque cardiovasculaire apparaît très tôt dans le processus de dégradation de la fonction rénale et aumente au fur et à mesure de la progression de l'insuffisance rénale. Un patient souffrant de maladie rénale a plus de probabilité de décéder d'un problème cardiovasculaire que d'évoluer vers l'insuffisance rénale terminale. Plusieurs études épidémiologiques menées aux Etats-Unis, que ce soit l'étude NHANES III (National Health And Nutrition Examination Survey) ou encore l'étude ARIC (Atherosclerosis Risk in Communities), démontrent toutes que ce risque cardiovasculaire s'élève particulièrement dès que la filtration glomérulaire s'abaisse en dessous de 60 ml/min/1,73 m². Ceci vient d'être confirmé sur un suivi de près de 3 ans chez plus d'un million de sujets, tant pour le risque de décès, d'accidents cardiovasculaires que d'hospitalisations. Par ailleurs, le devenir de patients ayant présenté un infarctus du myocarde est plus sombre en présence d'une insuffisance rénale. Chaque diminution de 10 ml/min de la filtration glomérulaire, à partir de 80 ml/min, augmente le risque de complication de 10% chez des sujets ayant souffert d'un infarctus. [less ▲]

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See detailComparison of linkage and association strategies for quantitative traits using the COGA dataset
McQueen, M. B.; Murphy, A.; Kraft, P. et al

in Genetic Epidemiology. Supplement (2005), 29(Suppl I), 1-9

Genome scans using dense single-nucleotide polymorphism ( SNP) data have recently become a reality. It is thought that the increase in information content for linkage analysis as a result of the denser ... [more ▼]

Genome scans using dense single-nucleotide polymorphism ( SNP) data have recently become a reality. It is thought that the increase in information content for linkage analysis as a result of the denser scans will help refine previously identified linkage regions and possibly identify new regions not identifiable using the sparser, microsatellite scans. In the context of the dense SNP scans, it is also possible to consider association strategies to provide even more information about potential regions of interest. To circumvent the multiple-testing issues inherent in association analysis, we use a recently developed strategy, implemented in PBAT, which screens the data to identify the optimal SNPs for testing, without biasing the nominal significance level. We compare the results from the PBAT analysis to that of quantitative linkage analysis on chromosome 4 using the Collaborative Study on the Genetics of Alcoholism data, as released through Genetic Analysis Workshop 14. [less ▲]

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See detailNon-small cell lung cancer and health-related quality of life (HRQOL): Is baseline HRQOL of prognostic value for survival?
Bottomley, A.; Smit, E.; Efficace, F. et al

in Quality of Life Research (2005), 14(9), 20501013

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See detailPredicting survival using health related quality of life scores in glioblastoma cancers: Findings from an international phase III randomised controlled trial.
Bottomley, A.; Taphoorn, M.; Coens, C. et al

in Journal of Clinical Oncology (2005), 23(16S), 9601

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See detailThe prognostic value of health related quality of life in colorectal cancer patients: A multivariate analysis using a bootstrap model-averaging approach
Efficace, F.; Bottomley, A.; Coens, C. et al

in Quality of Life Research (2005), 14(9), 21371030

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See detailGenomic screening in family-based association testing
Murphy, A.; McGueen, M. B.; Su, J. et al

in Genetic Epidemiology. Supplement (2005), 29

Due to the recent gains in the availability of single-nucleotide polymorphism data, genome-wide association testing has become feasible. It is hoped that this additional data may confirm the presence of ... [more ▼]

Due to the recent gains in the availability of single-nucleotide polymorphism data, genome-wide association testing has become feasible. It is hoped that this additional data may confirm the presence of disease susceptibility loci, and identify new genetic determinants of disease. However, the problem of multiple comparisons threatens to diminish any potential gains from this newly available data. To circumvent the multiple comparisons issue, we utilize a recently developed screening technique using family-based association testing. This screening methodology allows for the identification of the most promising single-nucleotide polymorphisms for testing without biasing the nominal significance level of our test statistic. We compare the results of our screening technique across univariate and multivariate family-based association tests. From our analyses, we observe that the screening technique, applied to different settings, is fairly consistent in identifying optimal markers for testing. One of the identified markers, TSC0047225, was significantly associated with both the ttth1 (p=0.004) and ttth1-ttth4 (p=0.004) phenotype(s). We find that both univariate- and multivariate-based screening techniques are powerful tools for detecting an association. [less ▲]

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See detailErratum: "Envelope solitons associated with electromagnetic waves in a magnetized pair plasma" [vol 12, pg 012319, 2005]
Cattaert, Tom ULg; Kourakis, I.; Shukla, P. K.

in Physics of Plasmas (2005), 12(5), 1

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See detailChronique de la 59ème Session de la Société Internationale Fernand de Visscher à Bochum (20-24 Septembre 2005)
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité (2005), LII

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See detailGenomic screening in family-based association testing and the multiple testing problem
Van Steen, Kristel ULg; McQueen, M. B.; Herbert, A. et al

in Genetic Epidemiology. Supplement (2005), 28

The Human Genome Project and its spin- offs are making it increasingly feasible to determine the genetic basis of complex traits using genome- wide association studies. The statistical challenge of ... [more ▼]

The Human Genome Project and its spin- offs are making it increasingly feasible to determine the genetic basis of complex traits using genome- wide association studies. The statistical challenge of analyzing such studies stems from the severe multiple-comparison problem resulting from the analysis of thousands of SNPs. Our methodology for genome- wide family- based association studies, using single SNPs or haplotypes, can identify associations that achieve genome- wide significance. In relation to developing guidelines for our screening tools, we determined lower bounds for the estimated power to detect the gene underlying the disease- susceptibility locus, which hold regardless of the linkage disequilibrium structure present in the data. We also assessed the power of our approach in the presence of multiple disease- susceptibility loci. Our screening tools accommodate genomic control and use the concept of haplotype- tagging SNPs. Our methods use the entire sample and do not require separate screening and validation samples to establish genome- wide significance, as population- based designs do. [less ▲]

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See detailA bootstrap model averaging technique to investigate the prognostic value for survival of quality of life information.
Bottomley, A.; Efficace, F.; Stuppe, R. et al

in Quality of Life Research (2005), 14(9), 21361022

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See detailTraduction de l'article de ELSTER J., 2005, « L’usage stratégique de l’argumentation »
Dubois, Christophe ULg

in Négociations (2005), 2

Lorsque des individus tentent de parvenir à un accord, deux grandes voies s’ouvrent à eux : soit ils essaient de se persuader l’un l’autre à l’aide d’arguments rationnels (on dit alors qu’ils argumentent ... [more ▼]

Lorsque des individus tentent de parvenir à un accord, deux grandes voies s’ouvrent à eux : soit ils essaient de se persuader l’un l’autre à l’aide d’arguments rationnels (on dit alors qu’ils argumentent), soit ils procèdent par un échange de menaces et de promesses (on dit alors qu’ils négocient). Tout au long de cet article, j’envisagerai les avantages et les inconvénients de ces deux registres de communication, tout en restant attentif au processus d’élaboration de l’accord ainsi qu’à la question de la qualité, si l’on peut dire, de l’accord recherché. Les principales illustrations empiriques de l’argumentation proviendront des débats de deux assemblées constituantes : la Convention fédérale de Philadelphie de 1787 et l’Assemblée constituante de Paris, de 1789 à 17911. J’utiliserai également d’autres exemples, comme certaines caractéristiques propres aux négociations salariales (voir aussi Elster, 1989, ch.4) et quelques aspects de l’allocation de ressources rares (Elster, 1992). [less ▲]

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See detailThe value of patient-reported symptoms as prognostic factors for survival in advanced colorectal cancer.
Efficace, F.; Bottomley, A.; Coens, C. et al

in Journal of Clinical Oncology (2005), 23(16S), 267

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See detailTight blood glucose control: a recommendation applicable to any critically ill patient?
Devos, P.; Preiser, Jean-Charles ULg

in Critical Care (2004), 8(6), 427-429

The issue of tight glucose control with intensive insulin therapy in critically ill patients remains controversial. Although compelling evidence supports this strategy in postoperative patients who have ... [more ▼]

The issue of tight glucose control with intensive insulin therapy in critically ill patients remains controversial. Although compelling evidence supports this strategy in postoperative patients who have undergone cardiac surgery, the use of tight glucose control has been challenged in other situations, including in medical critically ill patients and in those who have undergone non-cardiac surgery. Similarly, the mechanisms that underlie the effects of high-dose insulin are not fully elucidated. These arguments emphasize the need to study the effects of tight glucose control in a large heterogeneous cohort of intensive care unit patients. [less ▲]

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See detailThe use of protocols for nutritional support is definitely needed in the intensive care unit
Preiser, Jean-Charles ULg; Ledoux, Didier ULg

in Critical Care Medicine (2004), 32(11), 2354-2355

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See detailIndomethacin-responsive hemicrania associated with an extracranial vascular malformation: report of two cases
D'Alessio, C.; Ambrosini, A.; Colonnese, C. et al

in Cephalalgia : An International Journal of Headache (2004), 24(11), 997-1000

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See detailDepression in tension-type headache sufferers: bystander or villain?
Schoenen, Jean ULg

in Pain (2004), 111(3), 225-225

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See detailCross-modal facilitation is not specific to self-face recognition
Brédart, Serge ULg

in Consciousness & Cognition (2004), 13(3), 610-612

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See detailImagine imaging neural activity in crying infants and in their caring parents
Laureys, Steven ULg; Goldman, S.

in Behavioral and Brain Sciences (2004), 27(4), 465

Soltis' paper contains little data on the underlying neural substrate of the discussed signal function of early infant crying-probably because there is amazingly little known about it. We here discuss the ... [more ▼]

Soltis' paper contains little data on the underlying neural substrate of the discussed signal function of early infant crying-probably because there is amazingly little known about it. We here discuss the interest of functional neuroimaging as an objective measurement of brain activity in (1) early infants during crying and (2) parents hearing their offspring cry. [less ▲]

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See detailPotentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha (vol 23, pg 6200, 2003)
Adam, Emmanuelle; Quivy, Vincent; Bex, Françoise et al

in Molecular and Cellular Biology (2004), 24(15), 6890

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See detailUpdate of the standard numbering scheme for class B beta-lactamases
Garau, G.; Garcia-Saez, I.; Bebrone, Carine ULg et al

in Antimicrobial Agents and Chemotherapy (2004), 48(7), 2347-2349

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See detailAnti-IgE: a significant breakthrough in the treatment of airway allergic diseases
Louis, Renaud ULg

in Allergy (2004), 59(7), 698-700

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See detailInsight and the sleep committee
Maquet, Pierre ULg; Ruby, P.

in Nature (2004), 427(6972), 304-305

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See detailTumor invasion and metastasis: getting more basic to come closer to the patient - An interview with Lance A. Liotta
Castronovo, Vincenzo ULg

in International Journal of Developmental Biology (2004), 48(5-juin Sp. Iss. SI), 559-562

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See detailGenomic screening in family-based association testing
Van Steen, Kristel ULg; McQueen, M.; Herbert, A. et al

in Genetic Epidemiology (2004), 27

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See detailInvited comment concerning the article entitled "A pratical approach to ethical problems in surgical emergencies"
Lamy, Maurice ULg

in Acta Chirurgica Belgica (2004), 104(2, MAR-APR), 129-130

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See detailChronique de la 58ème Session de la Société Internationale Fernand de Visscher au Brésil (20-25 Septembre 2004)
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité (2004), LI

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See detailYaken detachment fold, Southern Tianshan, China
Hubert, Aurelia ULg; Suppe, J.; Wang, X. et al

in American Association of Petroleum Geologists Atlas (2004)

Yakeng anticline illustrates the importance of working in the thickness domain when interpreting detachment folds. Measure- ments in the thickness domain show that Yakeng has 1.2 km shorten- ing above a ... [more ▼]

Yakeng anticline illustrates the importance of working in the thickness domain when interpreting detachment folds. Measure- ments in the thickness domain show that Yakeng has 1.2 km shorten- ing above a basal two levels of major detachment, basal diapirism, basement folding, and a 2.4-km-thick growth sequence. [less ▲]

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See detailReply to "Comment on 'Detuning effects in the one-photon mazer' "
Bastin, Thierry ULg; Martin, John ULg

in Physical Review. A (2004), 70

We refute in this Reply the criticisms made by Abdel-Aty. We show that none of them are founded and we demonstrate very explicitly what is wrong with the arguments developed by this author.

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See detailErratum to : A complete fuzzy decision tree technique (vol 138, pg 221, 2003)
Olaru, C.; Wehenkel, Louis ULg

in Fuzzy Sets and Systems (2003), 140(3), 563-565

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See detailDoes sustained ERP activity in posterior lexico-semantic processing areas during short-term memory tasks only reflect activated long-term memory?
Majerus, Steve ULg; Van der Linden, Martial ULg; Collette, Fabienne ULg et al

in Behavioral and Brain Sciences (2003), 26(6), 746-747

We challenge Ruchkin et al.'s claim in reducing short-term memory (STM) to the active part of long-term memory (LTM), by showing that their data cannot rule out the possibility that activation of ... [more ▼]

We challenge Ruchkin et al.'s claim in reducing short-term memory (STM) to the active part of long-term memory (LTM), by showing that their data cannot rule out the possibility that activation of posterior brain regions could also reflect the contribution of a verbal STM buffer. [less ▲]

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See detailIs parenteral nutrition guilty?
Varga, P.; Griffiths, R.; Chiolero, R. et al

in Intensive Care Medicine (2003), 29(11), 1861-1864

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See detailGlutamine, a life-saving nutrient, but why?
Preiser, Jean-Charles ULg; Wernerman, J.

in Critical Care Medicine (2003), 31(10), 2555-2556

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See detailBirds return every spring like clockwork, but where is the clock?
Ball, G. F.; Balthazart, Jacques ULg

in Endocrinology (2003), 144(9), 3739-3741

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See detailOrigin and evolution of Proterozoic Anorogenic Magmatism - Preface
Vander Auwera, Jacqueline ULg

in Precambrian Research (2003), 124(2-4), 105-106

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See detailCardiologists and smoking
Kesteloot, H.; Pierard, Luc ULg

in Acta Cardiologica (2003), 58(3), 177-177

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