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 References of "Article"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 401 to 500 of 41456     1 2 3 4 5 6 7 8 9 10     Spread of hatch and delayed feed access affect post hatch performance of female broiler chicks up to day 5.Wang, Y.; Li, Yongzhen ; Willems, E. et alin Animal (2014)It is not rare that newly hatched chicks remain without feed for about 24 to 48 h before they are placed on farms due to a series of logistic operations. Furthermore, the spread in hatching time can also ... [more ▼]It is not rare that newly hatched chicks remain without feed for about 24 to 48 h before they are placed on farms due to a series of logistic operations. Furthermore, the spread in hatching time can also mount up to 30 to 48 h for late v. early hatchers. In other words, the practice is a complex combination of spread of hatch and delayed feed access. The present study was aimed to investigate the combined effects of hatching time with a delay in feed access of 48 h, starting from their hatch-time (biological age). When chicks had access to feed immediately after hatch, late hatchers had a higher feed intake and relative growth rate up to day 5 compared with their early hatched counterparts. Feed deprivation during the first 48 h resulted in retarded early growth rate, which was further aggravated by an impaired feed intake after refeeding. In addition, the differential effects of hatching time on relative growth rate and feed intake observed in immediately fed chicks were eliminated by the 48 h feed delay. The yolk utilization after hatch was faster for the late hatchers up to biological day 2 regardless of the feeding treatments. Hatching muscle glycogen content was higher in the late hatchers compared with that of their early counterparts at hatch and at biological day 2 independent of feeding treatment. Moreover, the liver glycogen content of the late hatchers was also higher at hatch. For the immediately fed chicks, the proportional breast muscle weight of the late hatchers was higher at biological day 2 and 5. For the starved chicks, on the other hand, this effect was only observed after they had access to feed (biological day 5). The different plasma T3 levels at hatch may have contributed to the different post hatch performance. It is concluded that the spread of hatch influenced post hatch performance, especially appetite and growth at least until day 5. Moreover, the delay in feed access interacted with the hatching time and caused adverse effects on the post hatch performance. [less ▲]Detailed reference viewed: 4 (0 ULg) Reprint of: Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich, et al.Gore, A. C.; Balthazart, Jacques ; Bikle, D. et alin Frontiers in neuroendocrinology (2014), 35(1), 2-5Detailed reference viewed: 2 (0 ULg) Romosozumab in Postmenopausal Women with Low Bone Mineral Density.McClung, Michael R.; Grauer, Andreas; Boonen, Steven et alin The New England journal of medicine (2014)Background Sclerostin is an osteocyte-derived inhibitor of osteoblast activity. The monoclonal antibody romosozumab binds to sclerostin and increases bone formation. Methods In a phase 2, multicenter ... [more ▼]Background Sclerostin is an osteocyte-derived inhibitor of osteoblast activity. The monoclonal antibody romosozumab binds to sclerostin and increases bone formation. Methods In a phase 2, multicenter, international, randomized, placebo-controlled, parallel-group, eight-group study, we evaluated the efficacy and safety of romosozumab over a 12-month period in 419 postmenopausal women, 55 to 85 years of age, who had low bone mineral density (a T score of -2.0 or less at the lumbar spine, total hip, or femoral neck and -3.5 or more at each of the three sites). Participants were randomly assigned to receive subcutaneous romosozumab monthly (at a dose of 70 mg, 140 mg, or 210 mg) or every 3 months (140 mg or 210 mg), subcutaneous placebo, or an open-label active comparator - oral alendronate (70 mg weekly) or subcutaneous teriparatide (20 mug daily). The primary end point was the percentage change from baseline in bone mineral density at the lumbar spine at 12 months. Secondary end points included percentage changes in bone mineral density at other sites and in markers of bone turnover. Results All dose levels of romosozumab were associated with significant increases in bone mineral density at the lumbar spine, including an increase of 11.3% with the 210-mg monthly dose, as compared with a decrease of 0.1% with placebo and increases of 4.1% with alendronate and 7.1% with teriparatide. Romosozumab was also associated with large increases in bone mineral density at the total hip and femoral neck, as well as transitory increases in bone-formation markers and sustained decreases in a bone-resorption marker. Except for mild, generally nonrecurring injection-site reactions with romosozumab, adverse events were similar among groups. Conclusions In postmenopausal women with low bone mass, romosozumab was associated with increased bone mineral density and bone formation and with decreased bone resorption. (Funded by Amgen and UCB Pharma; ClinicalTrials.gov number, NCT00896532 .). [less ▲]Detailed reference viewed: 20 (4 ULg) The effects of stress on singing voice accuracyLarrouy, Pauline ; Morsomme, Dominique in Journal of Voice (2014), 28(1), 52-58Objective: The quality of a music performance can be lessened or enhanced if the performer experiences stressful conditions. In addition, the quality of a sung performance requires control of the ... [more ▼]Objective: The quality of a music performance can be lessened or enhanced if the performer experiences stressful conditions. In addition, the quality of a sung performance requires control of the fundamental frequency of the voice, which is particularly sensitive to stress. The present study aimed to clarify the effects of stress on singing voice accuracy. Methods: Thirty-one music students were recorded in a stressful condition (i.e., a music examination) and a non-stressful condition. Two groups were defined according to the challenge level of the music examination (first and second music levels). Measurements were made by self-reported state anxiety (CSAI-2R questionnaire) and by observing heart rate activity (electrocardiogram) during each performance. In addition, the vocal accuracy of the sung performances was objectively analyzed. Results: As expected, state anxiety and heart rate were significantly higher on the day of the music examination than in the non-stressful condition for all the music students. However, the effect of stress was positive for the first-year students but negative for the second-year students, for whom the music examination was particularly challenging. In addition, highly significant correlations were found between the intensity of cognitive symptoms and the vocal accuracy criteria. Discussion: This study highlights the contrasting effects of stress on singing voice accuracy but also the need to consider the challenge level and perception of the symptoms in experimental and pedagogical settings. [less ▲]Detailed reference viewed: 50 (13 ULg) Correction of vitamin D insufficiency with combined strontium ranelate and vitamin D3 in osteoporotic patients.Rizzoli, R.; Dawson-Hughes, B.; Kaufman, J.-M. et alin European Journal of Endocrinology (2014), 170(3), 441-50OBJECTIVE: This study aims to investigate the efficacy and safety of oral fixed-dose combination of strontium ranelate 2 g/vitamin D3 1000 IU daily vs strontium ranelate 2 g daily for correcting vitamin D ... [more ▼]OBJECTIVE: This study aims to investigate the efficacy and safety of oral fixed-dose combination of strontium ranelate 2 g/vitamin D3 1000 IU daily vs strontium ranelate 2 g daily for correcting vitamin D insufficiency in osteoporosis. DESIGN: A 6-month international, randomized, double-blind, parallel-group, phase 3 study. METHODS: A total of 518 men and postmenopausal women aged >/=50 years with primary osteoporosis (T-score 22.5 nmol/l were included. Patients were allocated to strontium ranelate 2 g/vitamin D3 1000 IU daily (n=413) or strontium ranelate 2 g daily (n=105). The participants received calcium 1 g daily. The primary endpoint was serum 25(OH)D at last post-baseline evaluation during 3 months. RESULTS: Both groups were comparable at baseline. Mean baseline of 25(OH)D was 44.1+/-14.6 nmol/l. After 3 months, the percentage of patients with 25(OH)D >/=50 nmol/l was higher with strontium ranelate/vitamin D3 vs strontium ranelate (84 vs 44%, P<0.001; adjusted between-group odds ratio=6.7; 95% CI, 4.2-10.9). The efficacy of the fixed-dose combination on 25(OH)D was maintained at 6 months (86 vs 40%, P<0.001). Mean 25(OH)D was 65.1 and 49.5 nmol/l, respectively, after 3 months and 66.9 and 45.4 nmol/l after 6 months. Physical performance improved in both groups. Falls were 17 and 20% in the strontium ranelate/vitamin D3 and strontium ranelate groups respectively. Parathyroid hormone levels were inversely correlated with 25(OH)D. No clinically relevant differences in safety were observed. CONCLUSIONS: This study confirms the efficacy and safety of fixed-dose combination of strontium ranelate 2 g/vitamin D3 1000 IU for correction of vitamin D insufficiency in osteoporotic patients. [less ▲]Detailed reference viewed: 6 (1 ULg) Evaluating SGLT2 inhibitors for type 2 diabetes: pharmacokinetic and toxicological considerations.Scheen, André in Expert opinion on drug metabolism & toxicology (2014)Introduction: Inhibitors of sodium-glucose cotransporters type 2 (SGLT2), which increase urinary glucose excretion independently of insulin, are proposed as a novel approach for the management of type 2 ... [more ▼]Introduction: Inhibitors of sodium-glucose cotransporters type 2 (SGLT2), which increase urinary glucose excretion independently of insulin, are proposed as a novel approach for the management of type 2 diabetes mellitus (T2DM). Areas covered: An extensive literature search was performed to analyze the pharmacokinetic characteristics, toxicological issues and safety concerns of SGLT2 inhibitors in humans. This review focuses on three compounds (dapagliflozin, canagliflozin, empagliflozin) with results obtained in healthy volunteers (including drug-drug interactions), patients with T2DM (single dose and multiple doses) and special populations (those with renal or hepatic impairment). Expert opinion: The three pharmacological agents share an excellent oral bioavailability, long half-life allowing once-daily administration, low accumulation index and renal clearance, the absence of active metabolites and a limited propensity to drug-drug interactions. No clinically relevant changes in pharmacokinetic parameters were observed in T2DM patients or in patients with mild/moderate renal or hepatic impairment. Adverse events are a slightly increased incidence of mycotic genital and rare benign urinary infections. SGLT2 inhibitors have the potential to reduce several cardiovascular risk factors, and cardiovascular outcome trials are currently ongoing. The best positioning of SGLT2 inhibitors in the armamentarium for treating T2DM is still a matter of debate. [less ▲]Detailed reference viewed: 12 (1 ULg) Concomitant manipulation of NMDA- and AMPA-receptors to produce pro-cognitive drug effectsVignisse, Julie ; Steinbusch, Harry W.M.; Grigoriev, Vladimir et alin European Neuropsychopharmacology (2014), 24Bifunctional drug therapy targeting distinct receptor signaling systems can generate increased efficacy at lower concentrations compared to monofunctional therapy. Non-competitive blockade of the NMDA ... [more ▼]Bifunctional drug therapy targeting distinct receptor signaling systems can generate increased efficacy at lower concentrations compared to monofunctional therapy. Non-competitive blockade of the NMDA receptors or the potentiation of AMPA receptors is well documented to result in memory enhancement. Here, we compared the efficacy of the low-affinity NMDA receptor blocker memantine or the positive modulator of AMPA receptor QXX (in C57BL/6J at 1 or 5 mg/kg, ip) with new derivatives of isothiourea (0.5-1 mg/kg, ip) that have bifunctional efficacy. Low-affinity NMDA blockade by these derivatives was achieved by introducing greater flexibility into the molecule, and AMPA receptor stimulation was produced by a sulfamide-containing derivative of isothiourea. Contextual learning was examined in a step-down avoidance task and extinction of contextual memory was studied in a fear-conditioning paradigm. Memantine enhanced contextual learning while QXX facilitated memory extinction; both drugs were effective at 5 mg/kg. The new derivative IPAC-5 elevated memory scores in both tasks at the dose 0.5 mg/Kg and exhibited the lowest IC50 values of NMDA receptor blockade and highest potency of AMPA receptor stimulation. Thus, among the new drugs tested, IPAC-5 plicated the properties of memantine and QXX in one administration with increased potency. Our data suggest that a concomitant manipulation of NMDA- and AMPA-receptors results in pro-cognitive effects and supports the concept bifunctional drug therapy as a promising strategy to replace monofunctional therapies with greater efficacy and improved compliance. [less ▲]Detailed reference viewed: 5 (2 ULg) Assessing the effects of spatial discretization on large-scale flow model performance and prediction uncertaintyWildemeersch, Samuel ; Goderniaux, Pascal; Orban, Philippe et alin Journal of Hydrology (2014), 510Large-scale physically-based and spatially-distributed models (>100 km2) constitute useful tools for water management since they take explicitly into account the heterogeneity and the physical processes ... [more ▼]Large-scale physically-based and spatially-distributed models (>100 km2) constitute useful tools for water management since they take explicitly into account the heterogeneity and the physical processes occurring in the subsurface for predicting the evolution of discharge and hydraulic heads for several predictive scenarios. However, such models are characterized by lengthy execution times. Therefore, modelers often coarsen spatial discretization of large-scale physically-based and spatially-distributed models for reducing the number of unknowns and the execution times. This study investigates the influence of such a coarsening of model grid on model performance and prediction uncertainty. The improvement of model performance obtained with an automatic calibration process is also investigated. The results obtained show that coarsening spatial discretization mainly influences the simulation of discharge due to a poor representation of surface water network and a smoothing of surface slopes that prevents from simulating properly surface water-groundwater interactions and runoff processes. Parameter sensitivities are not significantly influenced by grid coarsening and calibration can compensate, to some extent, for model errors induced by grid coarsening. The results also show that coarsening spatial discretization mainly influences the uncertainty on discharge predictions. However, model prediction uncertainties on discharge only increase significantly for very coarse spatial discretizations. [less ▲]Detailed reference viewed: 22 (10 ULg) Subspace-based identification of a nonlinear spacecraft in the time and frequency domainsNoël, Jean-Philippe ; Marchesiello, Stefano; Kerschen, Gaëtan in Mechanical Systems & Signal Processing (2014), 43(1-2), 217-236The objective of the present paper is to address the identification of a strongly nonlinear satellite structure. To this end, two nonlinear subspace identification methods formulated in the time and ... [more ▼]The objective of the present paper is to address the identification of a strongly nonlinear satellite structure. To this end, two nonlinear subspace identification methods formulated in the time and frequency domains are exploited, referred to as the TNSI and FNSI methods, respectively. The modal parameters of the underlying linear structure and the coefficients of the nonlinearities will be estimated by these two approaches based on periodic random measurements. Their respective merits will also be discussed in terms of both accuracy and computational efficiency and the use of stabilisation diagrams in nonlinear system identification will be introduced. The application of interest is the SmallSat spacecraft developed by EADS-Astrium, which possesses an impact-type nonlinear device consisting of eight mechanical stops limiting the motion of an inertia wheel mounted on an elastomeric interface. This application is challenging for several reasons including the non-smooth nature of the nonlinearities, high modal density and high non-proportional damping. [less ▲]Detailed reference viewed: 19 (3 ULg) La description des zones climatiques terrestres. À propos d’Ératosthène, Hermès, 16, 3-16 POWELL et Cicéron, Songe de Scipion, 21Rochette, Bruno in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2014)Detailed reference viewed: 42 (3 ULg) Optimization of a formic/acetic acid delignification treatment on beech wood and its influence on the structural characteristics of the extracted ligninsSimon, Mathilde; Brostaux, Yves ; Vanderghem, Caroline et alin Journal of Chemical Technology & Biotechnology (2014), 89(1), 128-136Background In order to replace petrochemicals by bio-based lignin products in a lot of high value-added applications, a formic/acetic acid treatment was adapted to beech wood (Fagus sylvatica L.) for ... [more ▼]Background In order to replace petrochemicals by bio-based lignin products in a lot of high value-added applications, a formic/acetic acid treatment was adapted to beech wood (Fagus sylvatica L.) for lignin extraction. Results Beech wood particles were delignified at atmospheric pressure by a formic acid/acetic acid/water mixture. Cooking time and temperature were optimized for delignification, pulp yield and 2-furfural concentration. Response surface design analysis revealed that delignification yield increased with cooking time and temperature. Conclusion The multi-criteria optimization of delignification was used to find the ideal cooking conditions (5h07 min, 104.2°C) which could be satisfactory for the maximization of delignification (70.5%) and pulp yield (58.7%) and, to a lesser extent, for the minimization of 2-furfural production. Treatment conditions were found to influence the chemical structure of extracted lignins. Cooking time and temperature influenced inversely lignin molecular weights. [less ▲]Detailed reference viewed: 43 (27 ULg) Age-related decline in cognitive control: the role of fluid intelligence and processing speedManard, Marine ; Carabin, Delphine; Jaspar, Mathieu et alin BMC Neuroscience (2014), 15(7), Background Research on cognitive control suggests an age-related decline in proactive control abilities whereas reactive control seems to remain intact. However, the reason of the differential age effect ... [more ▼]Background Research on cognitive control suggests an age-related decline in proactive control abilities whereas reactive control seems to remain intact. However, the reason of the differential age effect on cognitive control efficiency is still unclear. This study investigated the potential influence of fluid intelligence and processing speed on the selective age-related decline in proactive control. Eighty young and 80 healthy older adults were included in this study. The participants were submitted to a working memory recognition paradigm, assessing proactive and reactive cognitive control by manipulating the interference level across items. Results Repeated measures ANOVAs and hierarchical linear regressions indicated that the ability to appropriately use cognitive control processes during aging seems to be at least partially affected by the amount of available cognitive resources (assessed by fluid intelligence and processing speed abilities). Conclusions This study highlights the potential role of cognitive resources on the selective age-related decline in proactive control, suggesting the importance of a more exhaustive approach considering the confounding variables during cognitive control assessment. [less ▲]Detailed reference viewed: 13 (3 ULg) Antioxidant capacity of hydrophilic food matrices: optimization and validation of ORAC assay.Kevers, Claire ; Sipel, Arnaud; PINCEMAIL, Joël et alin Food Analytical Methods (2014), 7It is widely accepted that ORAC is a useful method for assessing food extracts that contain various antioxidants. The principal aim of this study was to validate the ORAC assay. We first identified ... [more ▼]It is widely accepted that ORAC is a useful method for assessing food extracts that contain various antioxidants. The principal aim of this study was to validate the ORAC assay. We first identified parameters that can interfere with the ORAC assay and we optimized it. Then, experiments were conducted to determine the limits of linearity and response function, to determine the accuracy profiles to circumvent some of the drawbacks of traditional validation procedures. Trueness, selectivity and limits of quantification of the method were also determined. Our objective of ORAC method validation is thus to give guarantees that most of the results generated during use of this method will be close enough to unknown true value of antioxidant capacity of food matrices. The validation results indicate that the described method will give accurate and reliable results for Trolox equivalent values ranging from 50 to 200 µmol/L. [less ▲]Detailed reference viewed: 29 (5 ULg) The impact of aging and hearing status on verbal short-term memoryVerhaegen, Clémence ; Collette, Fabienne ; Majerus, Steve in Aging, Neuropsychology and Cognition (2014)The aim of this study is to assess the impact of hearing status on age-related decrease in verbal short-term memory (STM) performance. This was done by administering a battery of verbal STM tasks to ... [more ▼]The aim of this study is to assess the impact of hearing status on age-related decrease in verbal short-term memory (STM) performance. This was done by administering a battery of verbal STM tasks to elderly and young adult participants matched for hearing thresholds, as well as to young normal-hearing control participants. The matching procedure allowed us to assess the importance of hearing loss as an explanatory factor of age-related STM decline. We observed that elderly participants and hearing-matched young participants showed equal levels of performance in all verbal STM tasks, and performed overall lower than the normal hearing young control participants. This study provides evidence for recent theoretical accounts considering reduced hearing level as an important explanatory factor of poor auditory-verbal STM performance in older adults. [less ▲]Detailed reference viewed: 40 (7 ULg) Patients' preferences for osteoporosis drug treatment: a discrete-choice experiment.Hiligsmann, Mickaël ; Dellaert, Benedict G.; Dirksen, Carmen D. et alin Arthritis research & therapy (2014), 16(1), 36INTRODUCTION: The patient's perspective is becoming increasingly important in clinical and policy decisions. In this study, we aimed to evaluate the preferences of patients with, or at risk of ... [more ▼]INTRODUCTION: The patient's perspective is becoming increasingly important in clinical and policy decisions. In this study, we aimed to evaluate the preferences of patients with, or at risk of, osteoporosis for medication attributes, and to establish how patients trade between these attributes. METHODS: A discrete choice experiment survey was designed and patients were asked to choose between two hypothetical unlabelled drug treatments (and an opt-out option) that vary in five attributes: efficacy in reducing the risk of fracture, type of potential common side-effects, mode and frequency of administration and out-of-pocket costs. An efficient experimental design was used to construct the treatment option choice sets and a mixed logit panel data model was used to estimate patients' preferences and trade-offs between attributes. RESULTS: A total of 257 patients with, or at risk of, osteoporosis completed the experiment. As expected, patients preferred treatment with higher effectiveness and lower cost. They also preferred either an oral monthly tablet or 6-month subcutaneous injection above weekly oral tablets, 3-month subcutaneous, 3-month intravenous or yearly intravenous injections. Patients disliked being at risk of gastro-intestinal disorders more than being at risk of skin reactions and flu-like symptoms. There was significant variation in preferences across the sample for all attributes except subcutaneous injection. CONCLUSIONS: This study revealed that osteoporotic patients preferred 6-month subcutaneous injection and oral monthly tablet, and disliked gastro-intestinal disorders. Moreover, patients were willing to pay a personal contribution or to trade treatment efficacy for better levels of other attributes. Preferences for treatment attributes varied across patients and this highlights the importance of clinical decision-making taking individual preferences into account to improve osteoporosis care. [less ▲]Detailed reference viewed: 10 (2 ULg) Asymptotic Expansion based-Method for Equivalent Statistical LinearizationCanor, Thomas ; Blaise, Nicolas ; Denoël, Vincent in Probabilistic Engineering Mechanics (2014)Detailed reference viewed: 17 (6 ULg) Unusual occurrence of cocoons in population of the saddle gall midge, Haplodiplosis marginata (Diptera: Cecidomyiidae), in BelgiumCensier, Florence ; Chavalle, Sandrine; Skuhravá, Marcela et alin Journal of Insect Science [=JIS] (2014)The saddle gall midge, Haplodiplosis marginata (von Roser) (Diptera: Cecidomyiidae), is a phytophagous species that develops in saddle-shaped galls on stems of wheat Triticum vulgare, barley Hordeum ... [more ▼]The saddle gall midge, Haplodiplosis marginata (von Roser) (Diptera: Cecidomyiidae), is a phytophagous species that develops in saddle-shaped galls on stems of wheat Triticum vulgare, barley Hordeum sativum, rye Secale cereale and some other species of Poaceae. Only one generation develops per year. Full-grown larvae leave galls, drop onto the soil where they remain up to the springtime of the following year. Larvae do not usually spin cocoons. However, formation of cocoons by larvae was observed in populations developing in western Europe: in England in 1954, in the Netherlands in the 1960s and in Belgium in 2011. On the basis of our analysis, a part of the larval population forms cocoons as protection against unfavorable weather conditions, especially drought. [less ▲]Detailed reference viewed: 28 (6 ULg) Cuando la Historia se hace historia: (re)creación de Pancho Villa por Nellie Campobello en los Apuntes sobre la vida militar de Francisco Villa (1940)François, Jéromine in Anales de Literatura Hispanoamericana (2014), 43Detailed reference viewed: 26 (3 ULg) Lateral Magnetic Near-Field Imaging of Plasmonic Nanoantennas With Increasing ComplexityDenkova, D.; Verellen, N.; Silhanek, Alejandro et alin Small : Nano Micro (2014)The design of many promising, newly emerging classes of photonic metamaterials and subwavelength confinement structures requires detailed knowledge and understanding of the electromagnetic near-field ... [more ▼]The design of many promising, newly emerging classes of photonic metamaterials and subwavelength confinement structures requires detailed knowledge and understanding of the electromagnetic near-field interactions between their building blocks. While the electric field distributions and, respectively, the electric interactions of different nanostructures can be routinely measured, for example, by scattering near-field microscopy, only recently experimental methods for imaging the magnetic field distributions became available. In this paper, we provide direct experimental maps of the lateral magnetic near-field distributions of variously shaped plasmonic nanoantennas by using hollow-pyramid aperture scanning near-field optical microscopy (SNOM). We study both simple plasmonic nanoresonators, such as bars, disks, rings and more complex antennas. For the studied structures, the magnetic near-field distributions of the complex resonators have been found to be a superposition of the magnetic near-fields of the individual constituting elements. These experimental results, explained and validated by numerical simulations, open new possibilities for engineering and characterization of complex plasmonic antennas with increased functionality. [less ▲]Detailed reference viewed: 42 (1 ULg) Late Subatlantic history of the ombrotrophic Misten Bog (Eastern Belgium) based on high resolution pollen, testate amoebae and macrofossil analysisStreel, Maurice ; Beghin, Jérémie ; Gerrienne, Philippe et alin Geologica Belgica (2014), 17(2), 148-160Detailed reference viewed: 17 (4 ULg) L'émotion fondamentale: Sartre et BergsonCaeymaex, Florence ; Cormann, Grégory in Etudes Sartriennes (2014), 18Detailed reference viewed: 28 (6 ULg) Penser l'espace d'après le "Parménide"Gavray, Marc-Antoine in Dialogue : Canadian Philosophical Review = Dialogue : Revue Canadienne de Philosophie (2014)Detailed reference viewed: 18 (2 ULg) Sol-gel preparation and characterisation of SnO2 powders employed as catalyst for phenol photodegradationbenhebal hadj; chaib Messaoud; Léonard, Angélique et alin Scientia Iranica (2014)Crystallized pure SnO2 powders were prepared by the sol-gel process and were used as photocatalyst for the degradation of phenol under UV light at pH 6.5 and a temperature of 20°C. The physical properties ... [more ▼]Crystallized pure SnO2 powders were prepared by the sol-gel process and were used as photocatalyst for the degradation of phenol under UV light at pH 6.5 and a temperature of 20°C. The physical properties of photocatalyst were characterized by X-ray diffraction, Scanning Electron Microscopy, nitrogen adsorption-desorption and Ultraviolet-visible diffuse reflectance spectroscopy. The influences of different operating variables such as the pH, the photocatalyst loading, the initial concentration of phenol, were studied to improve the efficiency of phenol degradation. [less ▲]Detailed reference viewed: 33 (9 ULg) Une Histoire d'hypophyse, évolution des représentations et des concepts au fil du temps.JEDIDI, Haroun ; JEDIDI, Zayd ; BECKERS, Albert in Revue Médicale de Liège (2014)De par le rôle essentiel qu’il occupe, l’axe hypothalamo-hypophysaire, véritable chef d’orchestre du système endocrinien, constitue au niveau médical un important pourvoyeur de désordres. Il est assez ... [more ▼]De par le rôle essentiel qu’il occupe, l’axe hypothalamo-hypophysaire, véritable chef d’orchestre du système endocrinien, constitue au niveau médical un important pourvoyeur de désordres. Il est assez paradoxal de constater que malgré l’importance de ce système, celui-ci ait été presque complètement méconnu par les physiologistes des siècles passés. En nous basant sur les conceptions physiologiques des médecins philosophes de l’antiquité puis du moyen-âge et de la renaissance nous tenterons de comprendre pourquoi le rôle de l’hypophyse a été si longtemps méconnu. [less ▲]Detailed reference viewed: 32 (13 ULg) High Prevalence of Abdominal Aortic Aneurysm in Patients with Three-vessel Coronary Artery Disease.Durieux, R.; VAN DAMME, Hendrik ; Labropoulos, N. et alin European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (2014)OBJECTIVES: Currently, the prevalence of abdominal aortic aneurysm (AAA) in patients with coronary artery disease (CAD) and the correlation between CAD severity and AAA prevalence are not clearly known ... [more ▼]OBJECTIVES: Currently, the prevalence of abdominal aortic aneurysm (AAA) in patients with coronary artery disease (CAD) and the correlation between CAD severity and AAA prevalence are not clearly known. We conducted a prospective study to determine the prevalence of AAA in patients undergoing coronary angiography and to determine the risk factors and a coronary profile associated with AAA. METHODS: Over an 18-month period, abdominal aortic ultrasound was performed on 1,000 patients undergoing coronary angiography for suspected or known CAD, or prior to valve surgery. Clinical characteristics and coronary profile were collected from the patients. RESULTS: The overall number of previously repaired, already diagnosed, and new cases of AAA in the study population was 42, yielding a prevalence of 4.2%. Among the patients with newly detected AAAs, only two had an AAA diameter of >54 mm and were therefore treated surgically. In men aged >/=65 years, the prevalence reached 8.6%, while in men with three-vessel CAD it was 14.4%. Multivariate analysis showed that age >/=65 years (p = .003), male gender (p = .003), family history of AAA (p = .01), current smoking (p = .002), and three-vessel CAD (p < .001) were significantly associated with a higher prevalence of AAA. CONCLUSION: The prevalence of AAA was high in men aged >/=65 years and in those with three-vessel CAD regardless of age. While our findings do not prove the cost-effectiveness of screening for AAA in these high risk patients, they do support the usefulness of a quick ultrasound examination of the abdominal aorta during routine transthoracic echocardiography in such patients. [less ▲]Detailed reference viewed: 13 (7 ULg) Synthese bibliographique de l'influence du procédé d'extraction et de purification sur les caractéristiques et les propriétés d'une gomme de caroubeGillet, Sébastien ; Simon, mathilde; Paquot, Michel et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2014), 18(1), The carob tree is a species cultivated, in mediterranean countries, for its seeds. These seeds contain an endosperm rich in galactomannans used by the food industry for its texturing properties. After ... [more ▼]The carob tree is a species cultivated, in mediterranean countries, for its seeds. These seeds contain an endosperm rich in galactomannans used by the food industry for its texturing properties. After harvesting, the seeds pass through a decutilation and a degermination. Cleaned endosperms are then milled to give crude locust bean gum. The purification step consists in a flour solubilization and then a precipitation of the galactomannans. Purification influences the characteristics of the resulting gum. The solubilization temperature is the parameter that affects the most on the final characteristics of the product. If it is hot or cold, galactomannans with different structural characteristics (and thus very different physical properties in aqueous solutions) will be selected. [less ▲]Detailed reference viewed: 13 (4 ULg) As Above, so Below: Narrative Salience and Side Effects of National Innovation SystemsClaisse, Frédéric ; Delvenne, Pierre in Critical Policy Studies (2014), accepté à publicationDetailed reference viewed: 13 (2 ULg) Multi-scale modeling of mycosubtilin lipopeptides at the air/water interface: structure and optical second harmonic generationLoison, Claire; Nasir, Mehmet Nail ; Benichou, Emmanuel et alin Physical Chemistry Chemical Physics [=PCCP] (2014), 16Monolayers of the lipopeptide mycosubtilin are studied at the air/water interface. Their structure is investigated using molecular dynamics simulations. All-atom models suggest that the lipopeptide is ... [more ▼]Monolayers of the lipopeptide mycosubtilin are studied at the air/water interface. Their structure is investigated using molecular dynamics simulations. All-atom models suggest that the lipopeptide is flexible and aggregates at the interface. To achieve simulation times of several microseconds, a coarse-grained (CG) model based on the MARTINI force field was also used. These CG simulations describe the formation of half-micelles at the interface for surface densities up to 1 lipopeptide per nm2. In these aggregates, the tyrosine side chain orientation is found to be constrained: on average, its main axis, as defined along the C–OH bond, aligns along the interface normal and points towards the air side. The origin of the optical second harmonic generation (SHG) from mycosubtilin monolayers at the air/water interface is also investigated. The molecular hyperpolarizability of the lipopeptide is obtained from quantum chemistry calculations. The tyrosine side chain contribution to the hyperpolarizability is found to be dominant. The orientation distribution of tyrosine, associated with a dominant hyperpolarizability component along the C–OH bond of the tyrosine, yields a ratio of the susceptibility elements χ(2)ZZZ/χ(2)ZXX consistent with the experimental measurements recently reported by M. N. Nasir et al. [Phys. Chem. Chem. Phys., 2013, 15, 19919]. [less ▲]Detailed reference viewed: 15 (6 ULg) Near-to-Surface properties affecting bond strength in concrete repairCourard, Luc ; Piotrowski, Tomasz; Garbacz, Andrzejin Cement and Concrete Composites (2014), 46One of the main processes for repairing concrete structures is patch repair. Efficiency and durability of a repaired system depends on the bond between concrete substrate and repair material. By ... [more ▼]One of the main processes for repairing concrete structures is patch repair. Efficiency and durability of a repaired system depends on the bond between concrete substrate and repair material. By increasing the surface roughness, the surface treatment of concrete substrate can promote mechanical interlocking that is one of the basic mechanisms of adhesion. Nevertheless, some problems may arise from “co-lateral” effects of the treatment, especially due to the development of microcracks inside the substrate. In the presented paper, the effect of concrete substrate surface preparation has been characterized by roughness measurement, description of microcracking in the near-to-surface layer and a pull-off cohesion test. After repair, pull-off bond strength has been evaluated. It is concluded that selection of a suitable surface treatment technique should be preceded by the analysis of its aggressiveness in relation to the concrete substrate strength. A procedure for bond strength estimation using multiple regression approach, based on parameters describing surface quality really generated from various roughening techniques, is then proposed. [less ▲]Detailed reference viewed: 18 (3 ULg) Endothelial LGALS9 splice variant expression in endothelial cell biology and angiogenesisHeusschen, Roy ; Schulkens, Iris; van Beijnum, Judy et alin Biochimica et Biophysica Acta - Molecular Basis of Disease (2014)Detailed reference viewed: 9 (0 ULg) Amantadine, Apomorphine and Zolpidem in the Treatment of Disorders of ConsciousnessGosseries, Olivia ; Charland-Verville, Vanessa ; Thonnard, Marie et alin Current Pharmaceutical Design (2014), 20Survivors of severe brain injuries may end up in a state of 'wakeful unresponsiveness' or in a minimally conscious state. Pharmacological treatments of patients with disorders of consciousness aim to ... [more ▼]Survivors of severe brain injuries may end up in a state of 'wakeful unresponsiveness' or in a minimally conscious state. Pharmacological treatments of patients with disorders of consciousness aim to improve arousal levels and recovery of consciousness. We here provide a systematic overview of the therapeutic effects of amantadine, apomorphine and zolpidem in patients recovering from coma. Evidence from clinical trials using these commonly prescribed pharmacological agents suggests positive changes in the neurological status in patients, leading sometimes to dramatic improvements. These findings are discussed in the context of current hypotheses of these agents' therapeutic mechanisms on cerebral function. In order to enhance our understanding of the underlying pathophysiological mechanisms of these drugs, we suggest combining sensitive and specific behavioral tools with neuroimaging and electrophysiological measures in large randomized, double-blind, placebo-controlled experimental designs. We conclude that the pharmacokinetics and pharmacodynamics of amantadine, apomorphine and zolpidem need further exploration to determine which treatment would provide a better neurological outcome regarding the patient's etiology, diagnosis, time since injury and overall condition. [less ▲]Detailed reference viewed: 117 (8 ULg) Impact of in vivo T-cell depletion on outcome of AML patients in first CR given peripheral blood stem cells and reduced-intensity conditioning all-SCT from a HLA-identical sibling donor : a report from the Acute Leukemia Working Party of the European group for Blood and Marrow TransplantationBaron, Frédéric ; Labopin, M.; Blaise, D. et alin Bone Marrow Transplantation (2014)The impact of in vivo T-cell depletion on transplantation outcomes in patients transplanted with reduced-intensity conditioning (RIC) remains controversial. This study assessed the outcome of 1250 adult ... [more ▼]The impact of in vivo T-cell depletion on transplantation outcomes in patients transplanted with reduced-intensity conditioning (RIC) remains controversial. This study assessed the outcome of 1250 adult patients with de novo AML in first CR (CR1) given PBSC from HLA-identical siblings after chemotherapy-based RIC. A total of 554 patients did not receive any form of in vivo T-cell depletion (control group), whereas antithymocyte globulin (ATG) and alemtuzumab were given in 444 and 252 patients, respectively. The incidences of grade II-IV acute GVHD were 21.4, 17.6 and 10.2% in control, ATG and alemtuzumab patients, respectively (Po0.001). In multivariate analysis, the use of ATG and the use of alemtuzumab were each associated with a lower risk of chronic GVHD (Po0.001 each), but a similar risk of relapse, and of nonrelapse mortality, and similar leukemia-free survival and OS. Further, among patients given BU-based RIC, the use of o6 mg/kg ATG did not increase the risk of relapse (hazard ratio, HR¼1.1), whereas there was a suggestion for higher relapse risk in patients given X6 mg/kg ATG (HR¼1.4, P¼0.08). In summary, these data suggest that a certain amount of in vivo T-cell depletion can be safely used in the conditioning of AML patients in CR1 given PBSC after chemotherapy-based RIC. [less ▲]Detailed reference viewed: 8 (0 ULg) Introduction aux problèmes inversesCharles, Catherine in Notes de Statistique et d'Informatique (2014)cette note technique est une inititation aux problèmes inverses. Son objectif est d'expliquer au lecteur ses principes généraux, de montrer son large panel d'applications ainsi que de présenter ses ... [more ▼]cette note technique est une inititation aux problèmes inverses. Son objectif est d'expliquer au lecteur ses principes généraux, de montrer son large panel d'applications ainsi que de présenter ses méthodes de résolution les plus courantes. [less ▲]Detailed reference viewed: 17 (1 ULg) Levels of dechloranes and polybrominated diphenyl ethers (PBDEs) in human serum from FranceBrasseur, Catherine ; PIRARD, Catherine ; Scholl, Georges et alin Environment International (2014), 65Detailed reference viewed: 9 (5 ULg) Passive designs and strategies for low-cost housing using simulation-based optimization and different thermal comfort criteriaNguyen, Anh Tuan ; Reiter, Sigrid in Journal of Building Performance Simulation [=JBPS] (2014), 7(1), 68-81An optimum design of low-cost housing offers low-income urban inhabitants great opportunities to obtain a shelter at an affordable price and acceptable indoor thermal conditions. In this paper, the design ... [more ▼]An optimum design of low-cost housing offers low-income urban inhabitants great opportunities to obtain a shelter at an affordable price and acceptable indoor thermal conditions. In this paper, the design and operation of a low-cost dwelling were numerically optimized using a simulation-based approach. Three multi-objective cost functions including construction cost, thermal comfort performance and 50-year operating cost were applied for naturally ventilated and air-conditioned buildings. Thermal environment inside the house was controlled and assessed by two thermal comfort models. Optimization problems which consist of 18 design parameters and 6 ventilation strategies were examined by two population-based probabilistic optimization algorithms (particle swarm optimization and hybrid algorithm). Optimum designs corresponding to each objective function, differences in optimal solutions, energy saving by the adaptive comfort approach and optimization effectiveness were outlined. The optimization method used in this paper shows a considerable potential of comfort improvement, energy saving and operating cost reduction. [less ▲]Detailed reference viewed: 45 (12 ULg) Determination of the magnetic penetration depth in a superconducting Pb filmBrisbois, Jérémy ; Raes, Bart; Van de Vondel, Joris et alin Journal of Applied Physics (2014)By means of scanning Hall probe microscopy technique we accurately map the magnetic field pattern produced by Meissner screening currents in a thin superconducting Pb stripe. The obtained field profile ... [more ▼]By means of scanning Hall probe microscopy technique we accurately map the magnetic field pattern produced by Meissner screening currents in a thin superconducting Pb stripe. The obtained field profile allows us to quantitatively estimate the Pearl length Λ without the need of pre-calibrating the Hall sensor. This fact contrasts with the information acquired through the spatial field dependence of an individual flux quantum where the scanning height and the magnetic penetration depth combine in a single inseparable parameter. The derived London penetration depth λL coincides with the values previously reported for bulk Pb once the kinetic suppression of the order parameter is properly taken into account. [less ▲]Detailed reference viewed: 20 (7 ULg) Particle size distribution of limestone fillers: granulometry and specific surface area investigationsCourard, Luc ; Michel, Frédéric in Particulate Science and Technology (2014)Mineral fillers can be defined as “inert materials included in a mix design for some useful purpose”. They can be added to compounds in order to complete a large variety of final properties without ... [more ▼]Mineral fillers can be defined as “inert materials included in a mix design for some useful purpose”. They can be added to compounds in order to complete a large variety of final properties without increasing costs or to improve specific characteristics like hardness, brittleness, impact strength, compressive strength, softening point, fire resistance, surface texture, electrical conductivity, …etc. In Belgium, locally available limestone fillers are specifically very well-adapted for the optimisation of particle packing and flow behaviour of cementitious pastes in concrete mixes. Limestone fillers may be easily characterized in terms of chemical and mineralogical properties. These properties are fundamental for the study of the behaviour of concrete mixes in fresh state and for understanding interactions existing at the level of the Interfacial Transition Zone between aggregates and cement paste. These properties are however insufficiently discriminant and particle size, as well as shape distribution, seem to have a potential influence on physical phenomena which happen during the setting process. The aim of this paper is to compare five major techniques used to quantify the size and the shape of limestone fillers particles: laser diffraction scattering, wet sieving and image analysis for particle size measurement and BET adsorption and Blaine permeability methods for specific surface area. [less ▲]Detailed reference viewed: 30 (6 ULg) Spatial Planning as a driver of change in mobility and residential energy consumptionDujardin, Sébastien; Marique, Anne-Françoise ; Teller, Jacques in Energy & Buildings (2014), 68This paper analyses the impact of territorial structures upon energy consumption in the Walloon Region (Belgium). The rationale for this research is to consider the long-term influence of spatial planning ... [more ▼]This paper analyses the impact of territorial structures upon energy consumption in the Walloon Region (Belgium). The rationale for this research is to consider the long-term influence of spatial planning decisions upon energy consumption in both residential building stock and home-to-work commuting. The analysis has been conducted on a regional scale (16,844 km2) and includes urban, peri-urban and rural settlements. Those settlements that perform well in mobility also appear to perform well in terms of building energy consumption. Even though this is not generally the case, it further reveals that some rural settlements characterized by low density show good performance in terms of energy efficiency. This permits a much more progressive approach in terms of spatial planning, whereby compact cities may be viewed as part of the solution, albeit not the whole solution. [less ▲]Detailed reference viewed: 92 (31 ULg) Vol vaderlands leven en volksgezind streven: Het Kinkergenootschap te Luik (1886-ca. 1913)Steyaert, Kris in Negentiende Eeuw (2014)The Kinker Association was founded in 1886 for the benefit of the many Dutch-speaking Flemings living and working in francophone Liège. Organizing lectures on a variety of subjects, the Association ... [more ▼]The Kinker Association was founded in 1886 for the benefit of the many Dutch-speaking Flemings living and working in francophone Liège. Organizing lectures on a variety of subjects, the Association attempted to exert an emancipatory influence. Not only did it set up an extensive Dutch library but it also provided access to medical care and insurance. Above all, the Kinker Association wanted to boost the presence of Dutch-related cultural activities in the city. With its liberal sympathies and close links to the Willems Fonds, the Association met with opposition from various quarters, not least from the Catholic Church. This article looks in detail at the genesis, and rise and fall of the Association, its membership and its place and appeal within the wider socio-cultural context of late-nineteenth-century Wallonia. [less ▲]Detailed reference viewed: 14 (1 ULg) Reduced chaos expansions with random coefficients in reduced-dimensional stochastic modeling of coupled problemsArnst, Maarten ; Ghanem, Roger; Phipps, Eric et alin International Journal for Numerical Methods in Engineering (2014), 97We address the curse of dimensionality in methods for solving stochastic coupled problems with an emphasis on stochastic expansion methods such as those involving polynomial chaos expansions. The proposed ... [more ▼]We address the curse of dimensionality in methods for solving stochastic coupled problems with an emphasis on stochastic expansion methods such as those involving polynomial chaos expansions. The proposed method entails a partitioned iterative solution algorithm that relies on a reduced-dimensional representation of information exchanged between subproblems to allow each subproblem to be solved within its own stochastic dimension while interacting with a reduced projection of the other subproblems. The proposed method extends previous work by the authors by introducing a reduced chaos expansion with random coefficients. The representation of the exchanged information by using this reduced chaos expansion with random coefficients enables an expeditious construction of doubly stochastic polynomial chaos expansions that separate the effect of uncertainty local to a subproblem from the effect of statistically independent uncertainty coming from other subproblems through the coupling. After laying out the theoretical framework, we apply the proposed method to a multiphysics problem from nuclear engineering. [less ▲]Detailed reference viewed: 12 (3 ULg) Impact of purification and fractionation process on the chemical structure and physical properties of locust bean gumGillet, Sébastien ; Blecker, Christophe ; Aguedo, Mario et alin Carbohydrate Polymers (2014)Crude locust bean gum (CLBG) was purified and fractionated into two parts : the first was obtained by solubilization in water at 25 °C (GM25) and the second consisted in a further extraction at 80 °C on ... [more ▼]Crude locust bean gum (CLBG) was purified and fractionated into two parts : the first was obtained by solubilization in water at 25 °C (GM25) and the second consisted in a further extraction at 80 °C on the residual impoverished fraction (GM80). The complete structural characterization has shown that GM80 possessed relatively longer chain lengths than GM25, a slightly lower degree of galactose substitution and a somewhat sharper galactosyl distribution in substituted and unsubstituted regions. A physical behavior analysis was carried out on solubilization kinetics, viscosity, viscoelasticity and formation of associated gels with xanthan or carrageenan. The average structure of GM80 generated larger intra-chain, inter-chain and inter-molecular interactions, resulting in the appearance of a stronger network. Small structural differences therefore generated very different physical behaviors. This study thus allowed to establish, in a precise and complete manner, fractionation-purification-structure-function relationships of galactomannans extracted from carob. [less ▲]Detailed reference viewed: 17 (2 ULg) How to modify the photocatalytic activity of TiO2 thin films through their roughness by using additives. A relation between kinetics, morphology and synthesisMalengreaux, Charline ; Léonard, Géraldine ; Pirard, Sophie et alin Chemical Engineering Journal (2014), 243Detailed reference viewed: 11 (7 ULg) Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)?van Elk, C. E.; van de Bildt, M. W. G.; Jauniaux, Thierry et alin Veterinary pathology (2014)The virulence of morbilliviruses for toothed whales (odontocetes) appears to differ according to host species. In 4 species of odontocetes, morbilliviruses are highly virulent, causing large-scale ... [more ▼]The virulence of morbilliviruses for toothed whales (odontocetes) appears to differ according to host species. In 4 species of odontocetes, morbilliviruses are highly virulent, causing large-scale epizootics with high mortality. In 8 other species of odontocetes, including white-beaked dolphins (Lagenorhynchus albirostris), morbilliviruses have been found as an incidental infection. In these species, the virulence of morbilliviruses is not clear. Therefore, the admission of 2 white-beaked dolphins with morbillivirus infection into a rehabilitation center provided a unique opportunity to investigate the virulence of morbillivirus in this species. By phylogenetic analysis, the morbilliviruses in both animals were identified as a dolphin morbillivirus (DMV) most closely related to that detected in a white-beaked dolphin in Germany in 2007. Both animals were examined clinically and pathologically. Case No. 1 had a chronic neural DMV infection, characterized by polioencephalitis in the cerebrum and morbillivirus antigen expression limited to neurons and glial cells. Surprisingly, no nervous signs were observed in this animal during the 6 months before death. Case No. 2 had a subacute systemic DMV infection, characterized by interstitial pneumonia, leucopenia, lymphoid depletion, and DMV antigen expression in mononuclear cells and syncytia in the lung and in mononuclear cells in multiple lymphoid organs. Cause of death was not attributed to DMV infection in either animal. DMV was not detected in 2 contemporaneously stranded white-beaked dolphins. Stranding rate did not increase in the region. These results suggest that DMV is not highly virulent for white-beaked dolphins. [less ▲]Detailed reference viewed: 8 (0 ULg) La radicalité politique au bout du travail. Du suicide des ouvriers aux suicides en séries des employésCormann, Grégory in Quaderni (2014), 83Detailed reference viewed: 21 (4 ULg) The EU and the shifts of power in the international order: challenges and responsesSantander, Sébastian in European Foreign Affairs Review (2014), 19(1), 65-82This article revisits the debate about the place of Europe on the international stage. Faced with the growing power of emerging countries, what place can the European Union (EU) hope to occupy? In other ... [more ▼]This article revisits the debate about the place of Europe on the international stage. Faced with the growing power of emerging countries, what place can the European Union (EU) hope to occupy? In other words, is the world in the process of developing outside Europe, or is Europe positioning itself as one of the principal centres of the international order? In attempting to answer this vast and complex question, the article will examine three points.The first will look at the distribution of global power through the rise of emerging powers. Second, it will examine Europe in the light of changes affecting the international order. There are opposing interpretations.The vision of a Europe in decline is contrasted with arguments that present the Union of twenty-eight Member States as one of the leading poles of the new, emerging international order.The exaggerated nature of these visions persuaded us to favour a third way – that of a European player with relative influence, but ‘under construction’. [less ▲]Detailed reference viewed: 18 (3 ULg) Higher long-lasting ethanol sensitization after adolescent ethanol exposure in miceQuoilin, Caroline; Didone, Vincent ; Tirelli, Ezio et alin Psychopharmacology (2014), In pressRationale. Due to their maturing brain, adolescents are suggested to be more vulnerable to the long-term consequences of chronic alcohol use. Increased sensitization to the stimulant effects of ethanol is ... [more ▼]Rationale. Due to their maturing brain, adolescents are suggested to be more vulnerable to the long-term consequences of chronic alcohol use. Increased sensitization to the stimulant effects of ethanol is a possible consequence of ethanol exposure during adolescence. Objectives. The aim of this study was to characterize the long-term alterations in the stimulant effects of ethanol and in the rate of ethanol sensitization in mice pre-exposed to ethanol during adolescence in comparison to mice pre-exposed to ethanol in adulthood. Methods. Adolescent and adult female SWISS mice were injected with saline or ethanol (2.5 or 4 g/kg) during 14 consecutive days. After a three weeks period of ethanol abstinence, mice were tested as adults before and after a second exposure to daily repeated ethanol injections. Results. All mice pre-exposed to ethanol as adults or adolescents showed higher stimulant effects when re-exposed to ethanol three weeks later. However, this enhanced sensitivity to the stimulant effects of ethanol was of significantly higher magnitude in mice repeatedly injected with high ethanol doses (4g/kg) during adolescence. Furthermore, the increased expression of ethanol stimulant effects in these mice was maintained even after a second procedure of ethanol sensitization. Conclusions. Adolescence is a critical period for the development of a sensitization to ethanol stimulant properties providing that high intermittent ethanol doses are administered. These results might contribute to explain the relationship between age at first alcohol use and risks of later alcohol problems and highlight the dangers of repeated consumption of high alcohol amounts in young adolescents. [less ▲]Detailed reference viewed: 17 (6 ULg) A Givetian tintinnid-like palynomorph from Libya.Steemans, Philippe ; Breuer, P.; Ville de Goyet, F. de et alin Review of Palaeobotany and Palynology (2014), ?Detailed reference viewed: 21 (2 ULg) Impact of the invasive Asian clam, Corbicula spp., on a large river ecosytemPigneur, Lise-Marie; Falisse, Elodie; Roland, Kathleen et alin Freshwater Biology (2014), 59(3), 573-583During the past recent decades, Asiatic clams (Corbicula spp.) have spread spectacularly in several large European rivers. In the River Meuse, a transnational lowland river, an important chlorophyll a ... [more ▼]During the past recent decades, Asiatic clams (Corbicula spp.) have spread spectacularly in several large European rivers. In the River Meuse, a transnational lowland river, an important chlorophyll a decline has been recorded since the mid-2000s, which seems to be related to the invasion by these exotic bivalves. This study aimed at verifying that hypothesis, using clam density data from field surveys, water quality monitoring data, and a simulation model. Estimated Corbicula densities were between 50 and 900 individuals m-2, depending on the site. Using a maximum filtration rate per clam body mass of 0.086 m3 g C-1 day-1 at 20°C derived from the literature, we ran simulations with a non-stationary model to estimate the impact of the exotic bivalve on the river plankton and water quality. In the stretches where the invasive clams developed best, comparison with a clam-free scenario allowed estimating a 70 % phytoplankton biomass loss due to their filtration, leading to a 61 % loss of annual primary productivity. Model simulations also showed that zooplankton may have suffered as much as 75 % loss in terms of biomass. The simulations also point to substantial effects of the invasive Corbicula on the river oxygen budget and on nutrient cycling. We expect that, in the heavily regulated sectors of the river, the loss of planktonic production due to the invasive filter-feeders will negatively affect other suspension feeders and alter ecosystem function and productivity. [less ▲]Detailed reference viewed: 18 (3 ULg) Chromera velia, Endosymbioses and the Rhodoplex Hypothesis - Plastid Evolution in Cryptophytes, Alveolates, Stramenopiles and Haptophytes (CASH Lineages)Petersen, Jörn; Ludewig, Ann-Kathrin; Michael, Victoria et alin Genome Biology and Evolution (2014)The discovery of Chromera velia, a free-living photosynthetic relative of apicomplexan pathogens, has provided an unexpected opportunity to study the algal ancestry of malaria parasites. In this work we ... [more ▼]The discovery of Chromera velia, a free-living photosynthetic relative of apicomplexan pathogens, has provided an unexpected opportunity to study the algal ancestry of malaria parasites. In this work we compared the molecular footprints of a eukaryote-to-eukaryote endosymbiosis in C. velia to their equivalents in peridinin-containing dinoflagellates (PCD) to re- evaluate recent claims in favor of a common ancestry of their plastids. To this end, we established the draft genome and a set of full-length cDNA sequences from C. velia via next- generation sequencing. We documented the presence of a single coxI gene in the mitochondrial genome, which thus represents the genetically most reduced aerobic organelle identified so far, but focused our analyses on five “lucky genes” of the Calvin cycle. These were selected because of their known support for a common origin of complex plastids from cryptophytes, alveolates (represented by PCDs), stramenopiles and haptophytes (CASH) via a single secondary endosymbiosis with a red alga. As expected, our broadly sampled phylogenies of the nuclear- encoded Calvin cycle markers support a rhodophycean origin for the complex plastid of Chromera. However, they also suggest an independent origin of apicomplexan and dinophycean (PCD) plastids via two eukaryote-to-eukaryote endosymbioses. Although at odds with the current view of a common photosynthetic ancestry for alveolates, this conclusion is nonetheless in line with the deviant plastome architecture in dinoflagellates and the morphological paradox of four versus three plastid membranes in the respective lineages. Further support for independent endosymbioses is provided by analysis of five additional markers, four of them involved in the plastid protein import machinery. Finally, we introduce the “rhodoplex hypothesis” as a convenient way to designate evolutionary scenarios where CASH plastids are ultimately the product of a single secondary endosymbiosis with a red alga, but were subsequently horizontally spread via higher-order eukaryote-to-eukaryote endosymbioses. [less ▲]Detailed reference viewed: 8 (1 ULg) Avaliação da Qualidade de Vida Infantil: O Inventário Sistémico de Qualidade de Vida para CriançasFonseca, Marta; Missotten, Pierre ; Etienne, Anne-Marie et alin Psicologia, Reflexão e Crítica = Psychology, Reflection and Criticism (2014), 27(2), Introduction: Children’s quality of life evaluation has specific methodological aspects. Objective: To examine the psychometric properties of the Portuguese version of the Child Quality of Life Systemic ... [more ▼]Introduction: Children’s quality of life evaluation has specific methodological aspects. Objective: To examine the psychometric properties of the Portuguese version of the Child Quality of Life Systemic Inventory (CQLSI), which is based on an innovative conceptual and methodological approach to quality of life self-assessment, namely by being interactive and playful, having a psychometry which operates several scores and allowing an analysis of each domain of life. Methods: 120 Portuguese children, from 8 to 12 years old. Results: Internal consistency of the four scores of the CQLSI (State, Goal, Rank and Gap) is satisfactory; all scores have their own specificity. Data show convergent validity. On the other hand, no satisfactory factorial structure was found. Conclusion: Feasibility and psychometric adequacy of the CQLSI Portuguese version seems demonstrated. [less ▲]Detailed reference viewed: 107 (4 ULg) Spore assemblages from Upper Ordovician and lowermost Silurian sediments recovered from the Qusaiba-1 shallow core hole, Qasim region, central Saudi ArabiaWellman, Charles H.; Steemans, Philippe ; Miller, M.A.in Review of Palaeobotany and Palynology (2014), ?Detailed reference viewed: 38 (2 ULg) Continuity amid change in India’s political economy: from “socialist” to “neoliberal” India.Maiorano, Diego in Economic and Political Weekly (2014)The aim of this paper is to show that the social coalition that benefited from India’s central government’s economic policies remained unchanged between the pre and post economic reforms periods. More ... [more ▼]The aim of this paper is to show that the social coalition that benefited from India’s central government’s economic policies remained unchanged between the pre and post economic reforms periods. More specifically, this paper will argue that the economic policies promoted by the central government between 1980 and 2004 – irrespective of the political party heading the Cabinet – mostly benefited the middle class and the corporate sector, while the poor and the rural world were clearly relegated to a secondary position in the governments’ policy priorities. The paper will highlight six important lines of continuity in India’s economic policy and will argue that if we look at who the “winner” and the “losers” of these policy processes are, the economic reforms of the early 1990s do not separate two different phases of India’s development path. From this point of view the election of the United Progressive Alliance (UPA) government in 2004 might constitute a more important break with the past. [less ▲]Detailed reference viewed: 18 (1 ULg) Osteonecrosis of the jaw in a male osteoporotic patient treated with denosumabNEUPREZ, Audrey ; Coste, S; Rompen, Eric et alin Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2014), 25Osteonecrosis of the jaw (ONJ) is a clinical condition associated with long-term exposure to inhibitors of bone resorption, mainly bisphosphonates. Denosumab (DMab) is a human monoclonal antibody of the ... [more ▼]Osteonecrosis of the jaw (ONJ) is a clinical condition associated with long-term exposure to inhibitors of bone resorption, mainly bisphosphonates. Denosumab (DMab) is a human monoclonal antibody of the receptor activator of nuclear factor kappa-B ligand. It prevents osteoclast-mediated bone resorption and is widely prescribed for the management of postmenopausal osteoporosis. Whereas ONJ has already been reported in women treated with DMab, we report for the first time the development of ONJ, following tooth extraction, in a male patient treated for idiopathic osteoporosis with DMab. Due to the constant increase in DMab prescription, for the management of osteoporosis, in both genders, physicians should be made aware of this potential risk. [less ▲]Detailed reference viewed: 31 (10 ULg) Response to Dr Bolland's eLetter: Strontium and cardiovascular events.REGINSTER, Jean-Yves in Annals of the rheumatic diseases (2014), 73(2), 9Detailed reference viewed: 6 (2 ULg) La radicalité ouvrière en mots et en actes. Polysémie des termes et disqualification politiqueGeuens, Geoffrey ; Hamers, Jérémy in Quaderni : la Revue de la Communication (2014), 84Detailed reference viewed: 24 (7 ULg) A Clinical and Pathological Overview of Vulvar Condyloma Acuminatum, Intraepithelial Neoplasia and Squamous Cell CarcinomaLEONARD, Boris ; Kridelka, Frédéric ; DELBECQUE, Katty et alin BioMed Research International (2014)Detailed reference viewed: 18 (9 ULg) Plant Water Uptake in Drying SoilsLobet, Guillaume ; Couvreur, Valentin; Meunier, Félicien et alin Plant Physiology (2014), in pressDetailed reference viewed: 9 (2 ULg) Characterization of multi-walled carbon nanotube dispersion in resorcinol-formaldehyde aerogelHaghgoo, Majid; Yousefi, Ali Akbar; Zohouriaan Mehr, Mohammad Jalal et alin Microporous & Mesoporous Materials (2014), 184Detailed reference viewed: 11 (1 ULg) Genetic basis of congenital erythrocytosis: mutation update and online databases.Bento, Celeste; Percy, Melanie J.; Gardie, Betty et alin Human mutation (2014), 35(1), 15-26Congenital erythrocytosis (CE), or congenital polycythemia, represents a rare and heterogeneous clinical entity. It is caused by deregulated red blood cell production where erythrocyte overproduction ... [more ▼]Congenital erythrocytosis (CE), or congenital polycythemia, represents a rare and heterogeneous clinical entity. It is caused by deregulated red blood cell production where erythrocyte overproduction results in elevated hemoglobin and hematocrit levels. Primary congenital familial erythrocytosis is associated with low erythropoietin (Epo) levels and results from mutations in the Epo receptor gene (EPOR). Secondary CE arises from conditions causing tissue hypoxia and results in increased Epo production. These include hemoglobin variants with increased affinity for oxygen (HBB, HBA mutations), decreased production of 2,3-bisphosphoglycerate due to BPGM mutations, or mutations in the genes involved in the hypoxia sensing pathway (VHL, EPAS1, and EGLN1). Depending on the affected gene, CE can be inherited either in an autosomal dominant or recessive mode, with sporadic cases arising de novo. Despite recent important discoveries in the molecular pathogenesis of CE, the molecular causes remain to be identified in about 70% of the patients. With the objective of collecting all the published and unpublished cases of CE the COST action MPN&MPNr-Euronet developed a comprehensive Internet-based database focusing on the registration of clinical history, hematological, biochemical, and molecular data (http://www.erythrocytosis.org/). In addition, unreported mutations are also curated in the corresponding Leiden Open Variation Database. [less ▲]Detailed reference viewed: 9 (0 ULg) "Je ne connais pas Ben Sadok". Quelques remarques sur le témoignage de Sartre au procès Ben SadokCormann, Grégory ; Bourgault, Jeanin Genesis (2014), 39Detailed reference viewed: 50 (2 ULg) Deletion of exons 1-3 of the MEN1 gene in a large Italian family causes the loss of menin expression.Zatelli, Maria Chiara; Tagliati, Federico; Di Ruvo, Mauro et alin Familial cancer (2014)Multiple endocrine neoplasia type 1 (MEN1) syndrome is an autosomal dominant disease, characterized by parathyroid adenomas, endocrine gastroenteropancreatic tumors and pituitary adenomas, due to ... [more ▼]Multiple endocrine neoplasia type 1 (MEN1) syndrome is an autosomal dominant disease, characterized by parathyroid adenomas, endocrine gastroenteropancreatic tumors and pituitary adenomas, due to inactivating mutations of the MEN1 gene (chromosome 11q13). MEN1 mutations are mainly represented by nonsense, deletions/insertions, splice site or missense mutations that can be detected by direct sequencing of genomic DNA. However, MEN1 patients with large heterozygous deletions may escape classical genetic screening and may be misidentified as phenocopies, thereby hindering proper clinical surveillance. We employed a real-time polymerase chain reaction application, the TaqMan copy number variation assay, to evaluate a family in which we failed to identify an MEN1 mutation by direct sequencing, despite a clear clinical diagnosis of MEN1 syndrome. Using the TaqMan copy number variation assay we identified a large deletion of the MEN1 gene involving exons 1 and 2, in three affected family members, but not in the other nine family members that were to date clinically unaffected. The same genetic alteration was not found in a group of ten unaffected subjects, without family history of endocrine tumors. The MEN1 deletion was further confirmed by multiplex ligation-dependent probe amplification, which showed the deletion extended from exon 1 to exon 3. This new approach allowed us to correctly genetically diagnose three clinical MEN1 patients that were previously considered as MEN1 phenocopies. More importantly, we excluded the presence of genetic alterations in the unaffected family members. These results underline the importance of using a variety of available biotechnology approaches when pursuing a genetic diagnosis in a clinically suggestive setting of inherited endocrine cancer. [less ▲]Detailed reference viewed: 9 (1 ULg) Concepts d’efficience et de productivité de l’eau (synthèse bibliographique)Kambou, Donkora ; Xanthoulis, Dimitri ; Ouattara, Korodjouma et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2014), 18(1), Water efficiency and productivity indicators are used in many scientific disciplines, usually to account for water losses that occur during its use, or products generated per unit of water consumed. The ... [more ▼]Water efficiency and productivity indicators are used in many scientific disciplines, usually to account for water losses that occur during its use, or products generated per unit of water consumed. The interpretation of these indicators is very diverse in the literature. However, the majority of definitions consider water efficiency as a measure of the effectiveness of irrigation, and view water productivity as a measure of the effectiveness of the physiological processes of both biomass production and crop yield formation, linked to the actual consumption of water by the crops. Thus, the consensus seems to be for water application efficiency (Ea) to be considered as the ratio of actual evapotranspiration to the water applied and productivity as the ratio of yield to actual evapotranspiration. The point of divergence relates fundamentally to the understanding of the constituent expressions of productivity (PE, product/“water consumed”) and efficiency of water application (Ea, “water consumed”/“applied water”). Indeed, the term “water consumed” is referred to variously by several authors as “actual evapotranspiration”, “gross irrigation plus rainfall”, “evapotranspiration plus water lost at the plot but beneficial to other users”, etc. Furthermore, while providing more details on the concepts of efficiency and water productivity, this review shows that the factors affecting these indicators have not yet been sufficiently elucidated. Thus, one of the axes of investigation could be to model the application efficiency of water firstly, according to water management practices and secondly, in terms of productivity levels in relation to the crop establishment period. [less ▲]Detailed reference viewed: 22 (1 ULg) Transcranial magnetic stimulation combined with high density EEG in alered state of consciousnessNapolitani, M.; Bodart, Olivier ; Canali, P. et alin Brain injury : [BI] (2014), xx(x), -Detailed reference viewed: 27 (5 ULg) Endocrine disruptors: A relevant issue for neuroendocrinology also!Balthazart, Jacques ; Levine, Jon E.in Frontiers in neuroendocrinology (2014), 35(1), 1Detailed reference viewed: 3 (0 ULg) divand-1.0: n-dimensional variational data analysis for ocean observationsBarth, Alexander ; Beckers, Jean-Marie ; Troupin, Charles et alin Geoscientific Model Development [=GMD] (2014), 7A tool for multidimensional variational analysis (divand) is presented. It allows the interpolation and analysis of observations on curvilinear orthogonal grids in an arbitrary high dimensional space by ... [more ▼]A tool for multidimensional variational analysis (divand) is presented. It allows the interpolation and analysis of observations on curvilinear orthogonal grids in an arbitrary high dimensional space by minimizing a cost function. This cost function penalizes the deviation from the observations, the deviation from a first guess and abruptly varying fields based on a given correlation length (potentially varying in space and time). Additional constraints can be added to this cost function such as an advection constraint which forces the analysed field to align with the ocean current. The method decouples naturally disconnected areas based on topography and topology. This is useful in oceanography where disconnected water masses often have different physical properties. Individual elements of the a priori and a posteriori error covariance matrix can also be computed, in particular expected error variances of the analysis. A multidimensional approach (as opposed to stacking 2-dimensional analysis) has the benefit of providing a smooth analysis in all dimensions, although the computational cost is increased. Primal (problem solved in the grid space) and dual formulations (problem solved in the observational space) are implemented using either direct solvers (based on Cholesky factorization) or iterative solvers (conjugate gradient method). In most applications the primal formulation with the direct solver is the fastest, especially if an a posteriori error estimate is needed. However, for correlated observation errors the dual formulation with an iterative solver is more efficient. The method is tested by using pseudo observations from a global model. The distribution of the observations is based on the position of the ARGO floats. The benefit of the 3-dimensional analysis (longitude, latitude and time) compared to 2-dimensional analysis (longitude and latitude) and the role of the advection constraint are highlighted. The tool divand is free software, and is distributed under the terms of the GPL license (http://modb.oce.ulg.ac.be/mediawiki/index.php/divand). [less ▲]Detailed reference viewed: 79 (8 ULg) Modulating effect of COMT genotype on the brain regions underlying proactive control process during inhibitionJaspar, Mathieu ; Genon, Sarah ; Muto, Vincenzo et alin Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (2014), 50Introduction. Genetic variability related to the catechol-O-methyltransferase (COMT) gene (Val158Met polymorphism) has received increasing attention as a possible modulator of cognitive control functions ... [more ▼]Introduction. Genetic variability related to the catechol-O-methyltransferase (COMT) gene (Val158Met polymorphism) has received increasing attention as a possible modulator of cognitive control functions. Methods. In an event-related fMRI study, a modified version of the Stroop task was administered to three groups of 15 young adults according to their COMT Val158Met genotype [Val/Val (VV), Val/Met (VM) and Met/Met (MM)]. Based on the theory of dual mechanisms of control (Braver, et al., 2007), the Stroop task has been built to induce proactive or reactive control processes according to the task context. Results. Behavioral results did not show any significant group differences for reaction times but Val allele carriers individuals are less accurate in the processing of incongruent items. fMRI results revealed that proactive control is specifically associated with increased activity in the anterior cingulate cortex (ACC) in carriers of the Met allele, while increased activity is observed in the middle frontal gyrus (MFG) in carriers of the Val allele. Conclusion. These observations, in keeping with a higher cortical dopamine level in MM individuals, support the hypothesis of a COMT Val158Met genotype modulation of the brain regions underlying proactive control, especially in frontal areas as suggested by Braver et al. [less ▲]Detailed reference viewed: 31 (9 ULg) Brazil’s African strategy is a quest for power, profit and sharing knowledgeSantander, Sébastian in Africa at LSE (2014)Detailed reference viewed: 10 (1 ULg) Mary Anning’s legacy to French vertebrate palaeontologyVincent, Peggy; Taquet, Philippe; Fischer, Valentin et alin Geological Magazine (2014), 151(1), 7-20The real nature of marine reptile fossils found in England in between the 1700s to the beginning of the 1900s remained enigmatic, until Mary Anning's incredible fossil discoveries and their subsequent ... [more ▼]The real nature of marine reptile fossils found in England in between the 1700s to the beginning of the 1900s remained enigmatic, until Mary Anning's incredible fossil discoveries and their subsequent study by eminent English and French scientists. In 1820, Georges Cuvier acquired several ichthyosaur specimens found by Mary Anning, now kept or displayed in the Palaeontology Gallery of the MNHN in Paris. Four years later, Cuvier obtained a plesiosaur specimen from Mary Anning, only the second ever discovered. Cuvier was fascinated by these fossils and their study allowed him to apply his comparative anatomical method and to support his catastrophist theory. We re-examined these important specimens from an historical point of view and herein describe them taxonomically for the first time since Cuvier’s works. The Paris specimens belong to two different ichthyosaur genera (Ichthyosaurus and Leptonectes) and one plesiosaur genus (Plesiosaurus). [less ▲]Detailed reference viewed: 135 (2 ULg) Lignin extraction from Mediterranean agro-wastes: Impact of pretreatment conditions on lignin chemical structure and thermal degradation behaviorManara, Panagiota; Zabaniotou, Anastasia; Vanderghem, Caroline et alin Catalysis Today (2014), 223Three different types of Mediterranean, agro-industrial wastes (olive kernels, grape pomace/seeds, peach kernels), were subjected to two pretreatment processes, a chemical/organosolv and a physicochemical ... [more ▼]Three different types of Mediterranean, agro-industrial wastes (olive kernels, grape pomace/seeds, peach kernels), were subjected to two pretreatment processes, a chemical/organosolv and a physicochemical one. The organosolv process included lignocellulosic biomass treatment with formic acid/acetic acid/water (30/50/20, v/v%), for 3 h at 107 °C, while the physicochemical method was conducted by immersing the biomass in a water/ethanol (8/92, v/v%), H2SO4 0.32 M, solvent and further exposing the slurry to microwave irradiation (maximum 250 W) for 1/2 h at 150 °C. Both processes were evaluated regarding the achieved delignification and the purity of the extracted lignins. The effect of the pretreatment processes onto the structure and thermal decomposition behavior of the extracted lignins was investigated via FT-IR and TGA analysis, respectively. The objective of the research work was to investigate potential valorization routes for these biomass agro-residues in the context of a biorefinery, focusing on lignin extraction. The pretreatment results showed that the obtained lignins, derived from both procedures, were of high purity (>82 wt%). Under the organosolv procedure, peach kernel delignification showed the maximum value (∼16 wt%), while under microwave pretreatment, olive kernel delignification showed the maximum value (∼35 wt%). Grape pomace/seeds appeared to be the most resistant in both treatments. [less ▲]Detailed reference viewed: 21 (13 ULg) La primauté de l'intentionnalité et ses conséquences philosophiquesBoccaccini, Federico in Bulletin d'Analyse Phénoménologique (2014)Detailed reference viewed: 8 (0 ULg) LakeMIP Kivu: evaluating the representation of a large, deep tropical lake by a set of one-dimensional lake modelsThiery, Wim; Stepanenko, Victor M.; Fang, Xing et alin Tellus : Series A (2014), 66Detailed reference viewed: 6 (1 ULg) Functionalization of carbon xerogels for the preparation of palladium supported catalysts applied in sugar transformationsMager, Nathalie; Meyer, Nathalie; Léonard, Alexandre et alin Applied Catalysis B : Environmental (2014), 148-149Detailed reference viewed: 26 (5 ULg) Un monde entre accélération et incertitudesSantander, Sébastian in Interventions Economiques = Papers in Political Economy (2014)Detailed reference viewed: 17 (5 ULg) Experimental investigation on ferritic stainless steel columns in fireTondini, Nicola; Rossi, Barbara; Franssen, Jean-Marc in Fire Safety Journal (2014)This paper presents the performance of EN 1.4003 ferritic stainless steel hollow section columns when exposed to fire loading. Experimental analysis of the behaviour of ferritic stainless steel structural ... [more ▼]This paper presents the performance of EN 1.4003 ferritic stainless steel hollow section columns when exposed to fire loading. Experimental analysis of the behaviour of ferritic stainless steel structural members in fire represents a novelty. In detail, three column tests were carried out in the framework of the RFCS project named Structural Applications of Ferritic Stainless Steels (SAFSS, RFSR-CT-2010-00026). Tubular thin-walled members were considered in this study because structural applications of ferritic stainless steels generally incorporate such profiles. Three columns were tested: two square hollow sections (SHS) and a rectangular hollow section (RHS) of different length. Fire loading was applied under a constant concentrically compressive load. Identical column tests at room temperature are also reported. [less ▲]Detailed reference viewed: 14 (0 ULg) Development of the simultaneous detection of Ralstonia solanacearum race 3 and clavibacter michiganensis subsp. Sepedonicus in potato tubers by a multiplex real-time PCR assayMassart, Sébastien ; Nagy, Catherine; Jijakli, Haissam in European Journal of Plant Pathology (2014), 138Detailed reference viewed: 11 (0 ULg) A new Lower Cretaceous ichthyosaur from Russia reveals skull shape conservatism within OphthalmosaurinaeFischer, Valentin ; Arkhangelsky, Maxim; Uspensky, Gleb et alin Geological Magazine (2014), 151(1), 60-70Ophthalmosaurinae is a recently recognized clade of derived ichthyosaurs (marine reptiles) ranging from the Bajocian (Middle Jurassic) to the late Albian (late Early Cretaceous). Whereas the Middle-Late ... [more ▼]Ophthalmosaurinae is a recently recognized clade of derived ichthyosaurs (marine reptiles) ranging from the Bajocian (Middle Jurassic) to the late Albian (late Early Cretaceous). Whereas the Middle-Late Jurassic ophthalmosaurine Ophthalmosaurus is often regarded as a hyperspecialized deep diver, very little is known about the anatomy, evolutionary history, and ecology of Cretaceous ophthalmosaurines because of the scarcity of the fossils and the lack of well-preserved skull material. Here, we describe the skull of a new basal ophthalmosaurine ichthyosaur, Leninia stellans gen. et sp. nov., from the lower Aptian of western Russia, and compare the ocular characteristics of ophthalmosaurids. Leninia is recovered as a basal ophthalmosaurine; it possesses unique traits such as star-shaped frontal–parietal sutures as well as features previously thought to be unique to Ophthalmosaurus such as a supratemporal–stapes contact. A large sclerotic aperture – significantly bigger than in platypterygiine ophthalmosaurids and similar to that of the largest-eyed modern animals (giant and colossal squids) – and reduced dentition appear widespread within ophthalmosaurines. This conservatism suggests ophthalmosaurine ophthalmosaurids occupied similar ecological niche(s) throughout their long evolutionary history. [less ▲]Detailed reference viewed: 132 (8 ULg) Final Overall Survival: Fulvestrant 500 mg vs 250 mg in the Randomized CONFIRM Trial.Leo, Angelo Di; Leo, Angelo Di; Jerusalem, Guy et alin Journal of the National Cancer Institute (2014), 106(1), 337BACKGROUND: At the time of the initial analysis of overall survival (OS) for the Comparison of Faslodex in Recurrent or Metastatic Breast Cancer (CONFIRM) randomized, double-blind, phase III trial ... [more ▼]BACKGROUND: At the time of the initial analysis of overall survival (OS) for the Comparison of Faslodex in Recurrent or Metastatic Breast Cancer (CONFIRM) randomized, double-blind, phase III trial, approximately 50% of patients had died. A final analysis of OS was subsequently planned for when 75% of patients had died. METHODS: Patients were randomly assigned 1:1 to fulvestrant 500 mg administered as two 5-mL intramuscular injections on days 0, 14, and 28 and every 28 (+/-3) days thereafter or fulvestrant 250 mg administered as two 5-mL intramuscular injections (one fulvestrant and one placebo [identical in appearance to study drug]) on days 0, 14 (two placebo injections only), and 28 and every 28 (+/-3) days thereafter. OS was analyzed using an unadjusted log-rank test. No adjustments were made for multiplicity. Serious adverse events (SAEs) and best response to subsequent therapy were also reported. All statistical tests were two-sided. RESULTS: In total, 736 women (median age = 61.0 years) were randomly assigned to fulvestrant 500mg (n = 362) or 250mg (n = 374). At the final survival analysis, 554 of 736 (75.3%) patients had died. Median OS was 26.4 months for fulvestrant 500mg and 22.3 months for 250mg (hazard ratio = 0.81; 95% confidence interval = 0.69-0.96; nominal P = .02). There were no clinically important differences in SAE profiles between the treatment groups; no clustering of SAEs could be detected in either treatment group. Type of first subsequent therapy and objective responses to first subsequent therapy were well balanced between the two treatment groups. CONCLUSIONS: In patients with locally advanced or metastatic estrogen receptor-positive breast cancer, fulvestrant 500mg is associated with a 19% reduction in risk of death and a 4.1-month difference in median OS compared with fulvestrant 250mg. Fulvestrant 500mg was well tolerated, and no new safety concerns were identified. [less ▲]Detailed reference viewed: 7 (2 ULg) Screening for malnutrition in lung cancer patients undergoing therapyBARTHELEMY, Nicole ; Streel, Sylvie ; Donneau, Anne-Françoise et alin Supportive Care in Cancer (2014)Detailed reference viewed: 6 (2 ULg) Le dernier maillon de la chaîne des tourbières des hauts-plateaux ardennais : le projet LIFE+ « restauration des habitats naturels de l’Ardenne liégeoise »Plunus, Julie; Parkinson, Denis ; Frankard, Philippe et alin Forêt Wallonne (2014)Detailed reference viewed: 12 (2 ULg) Indian Institutions in the Early 1980s: The Pre-history of the Great TransformationMaiorano, Diego in Modern Asian Studies (2014)In 1989 India’s political system underwent a process of profound change which affected the entire institutional setup of the country. Power was radically redistributed, as it began to flow from the ... [more ▼]In 1989 India’s political system underwent a process of profound change which affected the entire institutional setup of the country. Power was radically redistributed, as it began to flow from the central government to the states, and from the Prime Minister Office to the other institutions of the state. The paper seeks to show how things worked on the eve of such a redrawing of India’s institutional setup, by analysing the sever institutional crisis which occurred during Mrs Gandhi’s final term in office as India’s Prime Minister. In addition, an effort is made to link the working of India’s institutions to the configuration of the party system, thus stressing the importance of political dynamics in the functioning of parliamentary democracies. [less ▲]Detailed reference viewed: 9 (2 ULg) Constitutional Aspects of FTAs: a Colombian PerspectiveParra Santamaria, Lusmiriam Andrea ; De Lombaerde, Philippe; Lizarazo, Liliana et alin European Journal of Law (2014)Detailed reference viewed: 14 (1 ULg) The impact of lexical frequency on sentence comprehension in children with specific language impairmentLeclercq, Anne-Lise ; Majerus, Steve ; Jacob, Laura et alin Research in Developmental Disabilities (2014), 35Children with SLI generally exhibit poor sentence comprehension skills. We examined the specific impact of grammatical complexity and lexical frequency on comprehension performance, yielding contrasting ... [more ▼]Children with SLI generally exhibit poor sentence comprehension skills. We examined the specific impact of grammatical complexity and lexical frequency on comprehension performance, yielding contrasting results. The present study sheds new light on sentence comprehension in children with SLI by investigating a linguistic factor which has attracted little research interest: the impact of the lexical frequency of known words on sentence comprehension. We also examined the impact of grammatical complexity and sentence length by independently varying these two factors. Fifteen children with SLI, 15 age- and IQ-matched controls, and 15 controls matched on lexical and grammatical skills, performed sentence comprehension tasks in which three linguistic factors were manipulated: lexical frequency (sentences containing words of either low or high lexical frequency), grammatical complexity (sentence containing either a subject relative clause or an object relative clause) and sentence length (either short or long sentences). Results indicated that children with SLI performed more poorly overall compared to age- and IQmatched children and to lexical and morphosyntactic age-matched children. However, their performance was not more affected by either sentence length or clause type than that of control children. Only lexical frequency affected sentence comprehension to a greater extent in children with SLI relative to the control groups, revealing that SLI children’s sentence comprehension abilities are particularly affected by the presence of lowfrequency but familiar words. [less ▲]Detailed reference viewed: 15 (3 ULg) Facultative paedomorphosis and the pattern of intra- and interspecific variation in cranial skeleton: lessons from European newts (Ichthyosaura alpestris and Lissotriton vulgaris)Ivanović, Ana; Cvijanović, Milena; Denoël, Mathieu et alin Zoomorphology (2014), 133(1), 99-109Paedomorphosis, the presence of ancestral larval and juvenile traits that occur at the descendent adult stage, is an evolutionary phenomenon that shaped morphological evolution in many vertebrate lineages ... [more ▼]Paedomorphosis, the presence of ancestral larval and juvenile traits that occur at the descendent adult stage, is an evolutionary phenomenon that shaped morphological evolution in many vertebrate lineages, including tailed amphibians. Among salamandrid species, paedomorphic and metamorphic phenotypes can be observed within single populations (facultative paedomorphosis). Despite wide interest in facultative paedomorphosis and polymorphism produced by heterochronic changes (heterochronic polymorphism), the studies that investigate intraspecific morphological variation in facultative paedomorphic species are largely missing. By quantifying the cranium size and development (bone development and remodeling), we investigated the variation at multiple levels (i.e., between sexes, populations and species) of two facultatively paedomorphic European newt species: the alpine and the smooth newt. The pattern of variation between paedomorphs (individuals keeping larval traits at the adult stage) and metamorphs (metamorphosed adult individuals) varied between species and among populations within a single species. The patterns of variation in size and skull formation appear to be more uniform in the alpine than in the smooth newt, indicating that developmental constraints differed between species (more pronounced in alpine than in smooth newt). Our study shows that the cranial skeleton provides detailed insight in the pattern of variation and divergence in heterochronic polymorphism within and between species and open new questions related to heterochronic polymorphism and evolution of cranial skeleton. [less ▲]Detailed reference viewed: 89 (48 ULg) Erratum: SN 2007uy − metamorphosis of an aspheric Type Ib explosionRoy, Rupak in Monthly Notices of the Royal Astronomical Society (2014)The supernovae (SNe) of Type Ibc are rare and the detailed characteristics of these explosions have been studied only for a few events. Unlike Type II SNe, the progenitors of Type Ibc have never been ... [more ▼]The supernovae (SNe) of Type Ibc are rare and the detailed characteristics of these explosions have been studied only for a few events. Unlike Type II SNe, the progenitors of Type Ibc have never been detected in pre-explosion images. So, to understand the nature of their progenitors and the characteristics of the explosions, investigation of proximate events are necessary. Here we present the results of multi-wavelength observations of Type Ib \sn\ in the nearby ($\sim$ 29.7 Mpc) galaxy NGC 2770. Analysis of the photometric observations revealed this explosion as an energetic event with peak absolute $R$ band magnitude $-18.5\pm0.16$, which is about one mag brighter than the mean value ($-17.6\pm0.6$) derived for well observed Type Ibc events. The SN is highly extinguished, \ebv\ = 0.63$\pm$0.15 mag, mainly due to foreground material present in the host galaxy. From optical light curve modeling we determine that about 0.3 \msun\ radioactive $^{56}$Ni is produced and roughly 4.4 \msun\ material is ejected during this explosion with liberated energy $\sim 15\times10^{51}$ erg, indicating the event to be an energetic one. Through optical spectroscopy, we have noticed a clear aspheric evolution of several line forming regions, but no dependency of asymmetry is seen on the distribution of $^{56}$Ni inside the ejecta. The SN shock interaction with the circumburst material (CSM) is clearly noticeable in radio follow-up, presenting a Synchrotron Self Absorption (SSA) dominated light curve with a contribution of Free Free Absorption (FFA) during the early phases. Assuming a Wolf-Rayet (WR) star, with wind velocity $\ga 10^3 {\rm km~s}^{-1}$, as a progenitor, we derive a lower limit to the mass loss rate inferred from the radio data as $\dot{M} \ga 2.4\times10^{-5}$ \msun\,~yr$^{-1}$, which is consistent with the results obtained for other Type Ibc SNe bright at radio frequencies. [less ▲]Detailed reference viewed: 8 (3 ULg) Introduction to Mapping Diasporic SubjectivitiesMunos, Delphine ; Pandurang, Malain South Asian Diaspora (2014), 6(1), 1-5Detailed reference viewed: 17 (0 ULg) l'hypothermie induite dans l'encéphalopathie anoxo-ischémique du nouveau-néBARREA, Christophe ; Seghaye, Marie-Christine ; Battisti, Oreste in Percentile (2014)Detailed reference viewed: 7 (0 ULg) Understanding the performance of the FLake model over two African Great LakesThiery, Wim; Martynov, Andrey; Darchambeau, François et alin Geoscientific Model Development [=GMD] (2014), 7Detailed reference viewed: 5 (0 ULg) Ultrathin porous pavement made with high viscosity asphalt rubber binder: A better acoustic absorption?Luong, Jeanne ; Bueno, M.; Vazquez, V.F. et alin Applied Acoustics (2014), 79his work presents a non-destructive technique applied to ultrathin porous asphalt pavements that allows us to characterize their internal structure. Comparison between acoustic absorption data from ... [more ▼]his work presents a non-destructive technique applied to ultrathin porous asphalt pavements that allows us to characterize their internal structure. Comparison between acoustic absorption data from experimental tests with an impedance tube and analytical simulation leads to an optimization of intrinsic parameters, such as tortuosity, airflow resistivity and porosity. The studied ultrathin specimens are of a high air void content porous mixture made with conventional polymer modified bituminous binder and high viscosity rubber binder. It has been found that one of the studied mixtures presents less air void con- tent than specified by the manufacturer, and thus absorbs less noise as foreseen. Finally, in this case it appears that using a high viscosity asphalt rubber binder has no influence on maximum acoustic absorp- tion but on the frequency of appearance of this maximum, tortuosity and airflow resistivity. [less ▲]Detailed reference viewed: 5 (0 ULg) Epidemiological and nonclinical studies investigating effects of iron in carcinogenesis-A critical reviewBeguin, Yves ; Aapro, M.; Ludwig, H. et alin Critical Reviews in Oncology/Hematology (2014), 89The efficacy and tolerability of intravenous (i.v.) iron in managing cancer-related anemia and iron deficiency has been clinically evaluated and reviewed recently. However, long-term data in cancer ... [more ▼]The efficacy and tolerability of intravenous (i.v.) iron in managing cancer-related anemia and iron deficiency has been clinically evaluated and reviewed recently. However, long-term data in cancer patients are not available; yet, long-term i.v. iron treatment in hemodialysis patients is not associated with increased cancer risk. This review summarizes epidemiological and nonclinical data on the role of iron in carcinogenesis. In humans, epidemiological data suggest correlations between certain cancers and increased iron exposure or iron overload. Nonclinical models that investigated whether iron can enhance carcinogenesis provide only limited evidence relevant for cancer patients since they were typically based on high iron doses as well as injection routes and iron formulations which are not used in the clinical setting. Nevertheless, in the absence of long-term outcome data from prospectively defined trials in i.v. iron-treated cancer patients, iron supplementation should be limited to periods of concomitant anti-tumor treatment. [less ▲]Detailed reference viewed: 8 (1 ULg) Biostratigraphic significance of brachiopods near the Devonian–Carboniferous boundaryMottequin, Bernard ; Brice, Denise; Legrand-Blain, Mariein Geological Magazine (2014), 151The biostratigraphic significance of selected uppermost Famennian (Upper Devonian) and lower Tournaisian (Mississippian) brachiopod genera, belonging to the orders Rhynchonellida (e.g. Araratella ... [more ▼]The biostratigraphic significance of selected uppermost Famennian (Upper Devonian) and lower Tournaisian (Mississippian) brachiopod genera, belonging to the orders Rhynchonellida (e.g. Araratella), Spiriferida (e.g. Sphenospira, Prospira), Spiriferinida (Syringothyris) and Productida (except Chonetidina), is discussed. Owing to the difficulties of identifying productidine and strophalosiidine genera, in contrast to rhynchonellides and spiriferides, the biostratigraphic potential of the former has generally been overlooked. Brachiopods flourished in neritic environments that were unfavourable for conodonts and ammonoids. In the absence of the latter traditional marker fossils, they are potentially important for locating the Devonian–Carboniferous boundary in shallow water depositional settings in conjunction with rugose corals and foraminifers. On a worldwide scale, further work is required to reach a better assessment of the aftermath of the Hangenberg biological Crisis on brachiopods, notably in revising the faunas from the classical areas of the Famennian and Tournaisian stages in Western Europe. [less ▲]Detailed reference viewed: 26 (12 ULg) Strontiohurlbutite, SrBe2(PO4)2, a new mineral from Nanping no. 31 pegmatite, Fujian Province, Southeastern ChinaRao, C; Wang, R; Hatert, Frédéric et alin American Mineralogist (2014), 99Detailed reference viewed: 9 (2 ULg) The Rank Minrelation CoefficientMeyer, Patrick in Quality Technology & Quantitative Management (2014), 11Detailed reference viewed: 10 (2 ULg) A modeling approach to determine the importance of dynamic regulation of plant hydraulic conductivities on the water uptake dynamics in the soil-plant-atmosphere systemLobet, Guillaume ; Pagès, Loïc; Draye, Xavierin Ecological Modelling (2014), (0), 1-11Detailed reference viewed: 12 (3 ULg) Primary production in a tropical large lake: The role of phytoplankton compositionDarchambeau, François ; Sarmento, Hugo; Descy, Jean-Pierrein Science of the Total Environment (2014), 473-474Detailed reference viewed: 7 (0 ULg) La culture comme objetBadir, Sémir in Semiotica (2014), 198La culture peut-elle être un objet d’étude à part entière ? Les sciences de la culture le donnent implicitement à penser par leur intitulé même, à l’instar de ce qu’ont poursuivi, à l’égard de leurs ... [more ▼]La culture peut-elle être un objet d’étude à part entière ? Les sciences de la culture le donnent implicitement à penser par leur intitulé même, à l’instar de ce qu’ont poursuivi, à l’égard de leurs objets respectifs, les sciences de l’homme, de la société et de la vie. Une telle objectivation, toutefois, ne va pas de soi, les caractères définitoires de la culture — à la fois comme totalité et comme singularité — dérogent à l’objectivation scientifique ordinaire. Dans un premier temps, on commence par considérer trois tentatives d’objectivation de la culture menées en sémiotique, sous le rapport de la sémiosphère (Lotman), de l’esthésie (Rastier) et de la langue. Le crédit accordé à la troisième tentative nous invite à interroger, dans un second temps, le rapport entre langue, texte et culture à partir de la distinction théorique proposée par Hjelmslev entre analyse et fragmentation. Langue, texte et culture sont fonction d’un seul objet empirique pour lesquelles différentes focalisations sont possibles. C’est une fonction restreinte et analytique qui règle le rapport des textes à la langue ; au contraire c’est une fonction extensive, fragmentée et synthétique qui laisse voir les textes comme des œuvres insérées dans les pratiques de la culture. [less ▲]Detailed reference viewed: 8 (0 ULg) Stability of templated and nanoparticles dye-sensitized solar cells : photovoltaic and electrochemical investigation of degradation mechanisms at the photoelectrode interfaceDewalque, Jennifer ; Nguyen, Ngoc Duy ; Colson, Pierre et alin Electrochimica Acta (2014), 115(1), 478-486A key issue in the commercialization of dye-sensitized solar cells is to maintain high efficiency and long lifetime. As reported in the literature, dye-sensitized solar cells are stable under visible ... [more ▼]A key issue in the commercialization of dye-sensitized solar cells is to maintain high efficiency and long lifetime. As reported in the literature, dye-sensitized solar cells are stable under visible light soaking but thermal stress and UV exposure lead to efficiency degradation. However, all the stability studies published so far have been performed on cells whose TiO2 electrodes were prepared by tape casting or screen printing of nanoparticle pastes/inks. The present study concerns cells based on highly porous templated TiO2 electrodes, whose larger surface area could enhance the negative effects of thermal stress, light soaking and UV exposure. The long-term stability of these cells is compared with a classical nanoparticle-based cell using current-voltage measurements (I-V curves) and electrochemical impedance spectroscopy. Due to their higher active interface, templated cells are more sensitive than nanoparticle cells to UV illumination, although this can be easily solved in both cases by the use of a UV filter. The templated cells are as stable as the nanoparticle cells under visible light soaking (UV filtered). However, we showed that templated cells are more stable under thermal stress. Moreover, as evidenced by electrochemical impedance spectroscopy, templated cells show lower transfer resistance, as well as lower recombination resistance compared to nanoparticle cells. The crystallite connectivity promoted by the templating route seems to favor the electron transfers inside the porous layer. Using templated films in dye-sensitized solar cells is therefore really promising because higher conversion efficiencies are reached without promoting cell degradation. [less ▲]Detailed reference viewed: 57 (12 ULg) Resistance of through-plate component in beam-to-column joints with circular hollow columnsHoang, Van Long ; Demonceau, Jean-François ; Jaspart, Jean-Pierre in Journal of Constructional Steel Research (2014), 92A configuration of beam-to-column joint with circular hollow section columns is proposed. A vertical plate, called through-plate, passing through the column is used to support the beams. In order to ... [more ▼]A configuration of beam-to-column joint with circular hollow section columns is proposed. A vertical plate, called through-plate, passing through the column is used to support the beams. In order to facilitate connecting the beams, two horizontal plates, each side of the column, are welded to the upper side of the through-plate. The lower flanges of the steel beams are connected to the horizontal plates by bolts, and the upper flanges are attached to the concrete slab by shear connections. The joint is considered as hinges in the construction phase while semi-rigid and partial strength can be adopted for the joint behaviour during the exploitation time. A development on the through-plate component of the joint is presented in this paper. Global behaviour of the joint under hogging moment and shear force is analysed leading to a mechanical model of the through-plate component. Using the elastic buckling theory of plates, the analytical formulas for critical stresses of the through-plate are obtained. The coefficients taking into account boundary conditions, material plasticity and geometrical imperfection are determined by finite element analysis. The proposed model is validated by experimental results showing a good accuracy. The design guideline for the component is finally provided for the practical purpose. [less ▲]Detailed reference viewed: 22 (2 ULg) Pore-filling of Spiro-OMeTAD determined by Rutherford backscattering spectrometry in templated TiO2 photoelectrodesDewalque, Jennifer ; Colson, Pierre ; Thalluri, Venkata Visveswara Gopala Kris et alin Organic Electronics (2014), 15Liquid-state dye-sensitized solar cells can suffer from electrolyte evaporation and leakage. Therefore solid-state hole transporting materials are investigated as alternative electrolyte materials ... [more ▼]Liquid-state dye-sensitized solar cells can suffer from electrolyte evaporation and leakage. Therefore solid-state hole transporting materials are investigated as alternative electrolyte materials. However, in solid-state dye-sensitized solar cells, optimal TiO2 films thickness is limited to a few microns allowing the adsorption of only a low quantity of photoactive dye and thus leading to poor light harvesting and low conversion efficiency. In order to overcome this limitation, high surface area templated films are investigated as alternative to nanocrystalline films prepared by doctor-blade or screen-printing. Moreover, templating is expected to improve the pore accessibility what would promote the solid electrolyte penetration inside the porous network, making possible efficient charge transfers. In this study, films prepared from different structuring agents are discussed in terms of microstructural properties (porosity, crystallinity) as well as impact on the dye loading and Spiro-OMeTAD (2,2',7,7'-tetrakis-(N,N-di-p-methoxyphenylamine)9,9'-spirobifluorene) solid electrolyte filling. We first report Rutherford backscattering spectrometry as an innovative non-destructive tool to characterize the hole transporting materials infiltration. Templated films show dye loading more than two times higher than nanocrystalline films prepared by doctor-blade or screen-printing and solid electrolyte infiltration up to 88%. [less ▲]Detailed reference viewed: 64 (12 ULg) Lack of isocitrate lyase in Chlamydomonas leads to changes in carbon metabolism and in the response to oxidative stress under mixotrophic growth.Plancke, Charlotte; Vigeolas, Hélène ; Hohner, Ricarda et alin The Plant journal : for cell and molecular biology (2014), 77(3), 404-417Isocitrate lyase is a key enzyme of the glyoxylate cycle. This cycle plays an essential role in cell growth on acetate, and is important for gluconeogenesis as it bypasses the two oxidative steps of the ... [more ▼]Isocitrate lyase is a key enzyme of the glyoxylate cycle. This cycle plays an essential role in cell growth on acetate, and is important for gluconeogenesis as it bypasses the two oxidative steps of the tricarboxylic acid (TCA) cycle in which CO2 is evolved. In this paper, a null icl mutant of the green microalga Chlamydomonas reinhardtii is described. Our data show that isocitrate lyase is required for growth in darkness on acetate (heterotrophic conditions), as well as for efficient growth in the light when acetate is supplied (mixotrophic conditions). Under these latter conditions, reduced acetate assimilation and concomitant reduced respiration occur, and biomass composition analysis reveals an increase in total fatty acid content, including neutral lipids and free fatty acids. Quantitative proteomic analysis by 14 N/15 N labelling was performed, and more than 1600 proteins were identified. These analyses reveal a strong decrease in the amounts of enzymes of the glyoxylate cycle and gluconeogenesis in parallel with a shift of the TCA cycle towards amino acid synthesis, accompanied by an increase in free amino acids. The decrease of the glyoxylate cycle and gluconeogenesis, as well as the decrease in enzymes involved in beta-oxidation of fatty acids in the icl mutant are probably major factors that contribute to remodelling of lipids in the icl mutant. These modifications are probably responsible for the elevation of the response to oxidative stress, with significantly augmented levels and activities of superoxide dismutase and ascorbate peroxidase, and increased resistance to paraquat. [less ▲]Detailed reference viewed: 32 (19 ULg) Study of the energy distribution of the interface trap density in a GeSn MOS structure by numerical simulation of the electrical characteristicsBaert, Bruno ; Schmeits, Marcel ; Nguyen, Ngoc Duy in Applied Surface Science (2014), 291Using a custom-made numerical simulation tool, we performed a systematic study of the energy distribution of the interface trap density in a GeSn MOS structure and of their effect on the electrical ... [more ▼]Using a custom-made numerical simulation tool, we performed a systematic study of the energy distribution of the interface trap density in a GeSn MOS structure and of their effect on the electrical characteristics such as C–V and impedance spectra. Interface traps with various densities of states and energies in the bandgap have been investigated and the application of the conductance method was assessed. Based on a theoretical analysis, we obtained, as key results, direct connections between microscopic parameters of the structures and experimentally accessible features of the simulated macroscopic quantities. A straightforward relationship between the interface state density and the peaks in the conductance response is also highlighted. The dependence of the peak characteristics on the trap states was identified, as well as the effects of traps extending over large energy ranges in the bandgap. [less ▲]Detailed reference viewed: 42 (8 ULg)