References of "Article"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailDetection of laminin receptor mRNA in human cancer cell lines and colorectal tissues by in situ hybridization.
Campo, E.; Monteagudo, C.; Castronovo, Vincenzo ULg et al

in American Journal of Pathology (1992), 141(5), 1073-83

The 67-kd high-affinity laminin receptor (67 LR) is a gene product whose expression appears to be associated with the invasive and metastatic phenotype of a variety of human cancer cells. Northern blot ... [more ▼]

The 67-kd high-affinity laminin receptor (67 LR) is a gene product whose expression appears to be associated with the invasive and metastatic phenotype of a variety of human cancer cells. Northern blot hybridization has been routinely used to quantify the level of 67 LR mRNA from total cellular RNA extracts of homogenized tissue specimens or in vitro grown cell populations. This technique is useful to assess the average expression of the 67 LR mRNA of a particular sample but does not provide information about expression in specific cell types nor about heterogeneity of expression from cell to cell. In this study, we analyzed the expression of 67 LR mRNA in four human cancer cell lines with varying degrees of expression of 67 LR protein (renal cancer A-704, breast carcinoma MCF-7/4 and MCF-7/7, and pancreatic cancer Panc-1) using in situ hybridization performed with 67 LR riboprobes. Total cellular RNA was simultaneously extracted from the cell lines and hybridized on Northern blots with a 67 LR cDNA probe to assess the validity of the mRNA detection by in situ hybridization. Sixty-seven LR mRNA expression was higher in Panc-1 and MCF-7/4 cells than in MCF-7/7 and renal carcinoma A-704. There was a direct correlation (R2 = 0.88) between the in situ hybridization analysis and the mRNA levels detected by Northern blot analysis. The in situ hybridization method showed a heterogeneous expression of the 67 LR mRNA in the four cell lines with different subpopulations of cells showing a range from negative to high levels of the message. Sixteen freshly frozen human colorectal tissues (seven adenocarcinomas, five matched normal mucosae, and four adenomas) were also analyzed by in situ hybridization. The 67 LR mRNA was localized in normal and neoplastic epithelial cells. Adenocarcinoma cells showed a 1.6- to 5-fold higher expression (P < 0.02 according to the Wilcoxon-Mann-Whitney test) than did epithelial colonic cells from normal mucosae or adenomas. The signal tended to be stronger in poorly differentiated carcinomas and carcinomas with metastases than in moderately differentiated and nonmetastatic tumors. We conclude that the high expression of 67 LR mRNA in colorectal tumors is due to an increased production by tumor cells. Furthermore, in situ hybridization is an effective method to detect the expression of LR mRNA in cultured cell lines as well as in frozen tissue sections. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailDeterminants of serum zinc in a random population sample of four Belgian towns with different degrees of environmental exposure to cadmium
Thijs, Lutgarde; Staessen, Jan; Amery, Antoon et al

in Environmental Health Perspectives (1992), 98

This report investigated the distribution of serum zinc and the factors determining serum zinc concentration in a large random population sample. The 197 participants (959 men and 1018 women), 20-80 years ... [more ▼]

This report investigated the distribution of serum zinc and the factors determining serum zinc concentration in a large random population sample. The 197 participants (959 men and 1018 women), 20-80 years old, constituted a stratified random sample of the population of four Belgian districts, representing two areas with low and two with high environmental exposure to cadmium. For each exposure level, a rural and an urban area were selected. The serum concentration of zinc, frequently used as an index for zinc status in human subjects, was higher in men (13.1 µmole/L, range 6.5-23.0 µmole/L) than in women (12.6 µmoleL, range 6.3-23.2 µmole/L). In men, 20% of the variance of serum zinc was explained by age (linear and squared term, R=0.29), diurnal variation (r=0.29), and total cholesterol (r=0.16). After adjustment for these covariates, a negative relationship was observed between serum zinc and both blood (r= -0.10) and urinary cadmium (r= -0.14). In women, 11% of the variace could be explained by age (linear and squared term, R = 0.15), diurnal variation in serum zinc (r=0.27), creatinine clearance (r= -0.11), log y-glutamyltranspeptidase (r= 0.08), cholesterol (r= 0.07), contraceptive pill intake (r= -0.07), and log serum ferritin (r=0.06). Before and after adjustment for significant covariates, serum zinc was, on average, lowest in the two districts where the body burden of cadmium, as assessed by urinary cadmium excretion, was highest. These results were not altered when subjects exposed to heavy metals at work were excluded from analysis. [less ▲]

Detailed reference viewed: 8 (1 ULg)
See detailLa matière en suspension de la couche de surface du plateau continental nord-ouest européen. II. Teneur en métaux lourds et transfert dans la chaîne trophique
Bouquegneau, Jean-Marie ULg; Gobert, Sylvie ULg; Frankignoulle, Michel et al

in Bulletin de la Société Royale des Sciences de Liège (1992), 61

Samples of suspended matter (MS) from the North Sea have been analysed for its heavy metal content. Unexpected high levels of copper have been recorded. The Scheldt Estuary reveals to be an important ... [more ▼]

Samples of suspended matter (MS) from the North Sea have been analysed for its heavy metal content. Unexpected high levels of copper have been recorded. The Scheldt Estuary reveals to be an important source of zinc, lead and cadmium for the sea. The transfer of metals from the MS to mussels is low. [less ▲]

Detailed reference viewed: 11 (5 ULg)
Peer Reviewed
See detailChronic Ischaemic Gastritis: An Unusual Form of Splanchnic Vascular Insufficiency
VAN DAMME, Hendrik ULg; Jacquet, N.; Belaiche, Jacques ULg et al

in Journal of Cardiovascular Surgery (The) (1992), 33(4), 451-3

Three cases of erosive gastroduodenitis secondary to chronic splanchnic vascular insufficiency are reported. In all cases, pain failed to respond to conventional therapeutic measures for peptic ulcer ... [more ▼]

Three cases of erosive gastroduodenitis secondary to chronic splanchnic vascular insufficiency are reported. In all cases, pain failed to respond to conventional therapeutic measures for peptic ulcer disease. A patchy discolouration and erythematous mottling of the gastric mucosa, with scattered shallow aphthous ulcers, was seen on endoscopic examination. Angiography showed coeliac axis involvement in all patients, with insufficient mesenteric collateral pathways. Chronic gastritis resolved clinically and endoscopically after revascularization. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailPsychisme et greffe cardiaque
Triffaux, Jean-Marc ULg; Bertrand, Jean ULg

in Psychologie Médicale (1992)

Detailed reference viewed: 40 (3 ULg)
Peer Reviewed
See detailEnquête sur l'infestation du renard roux (Vulpes vulpes) par Echinococcus multilocularis en province de Luxembourg (Belgique)
Brochier, B.; Coppens, P.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (1992), 136

Detailed reference viewed: 23 (0 ULg)
Full Text
Peer Reviewed
See detailIntérêts et procédure d'ordre, obs. sous comm. Charleroi, 6 novembre 1991
Biquet, Christine ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1992)

Detailed reference viewed: 17 (6 ULg)
Full Text
Peer Reviewed
See detailManagement of High Turnover Osteoporosis with Calcitonin
Reginster, Jean-Yves ULg

in BONE (1992), 13(Suppl 2), 37-40

Osteoporosis, associated with a high turnover of bone and acute bone loss, occurs in a number of clinical models, such as following prolonged steroid therapy, extremity and spinal immobilisation, and ... [more ▼]

Osteoporosis, associated with a high turnover of bone and acute bone loss, occurs in a number of clinical models, such as following prolonged steroid therapy, extremity and spinal immobilisation, and often is associated with fracture. Confinement to bed and subsequent hypodynamism relating to the pain following a vertebral fracture may activate the process of high bone turnover and acute bone loss. In postmenopausal women, the acute bone loss resulting from such clinical pictures may be superimposed on to the natural course of bone loss occurring in many postmenopausal women. Salmon calcitonin, a potent inhibitor of osteoclast activity, has been shown to prevent bone loss in all clinical models of acute bone loss due to increased bone turnover and osteoclastic resorption. In addition, salmon calcitonin has a potent analgesic effect, thereby causing a reduction in bone pain and improvement in functional capacity. For these reasons, calcitonin remains a first-line therapy in bone loss related to a hyper-resorptive state. [less ▲]

Detailed reference viewed: 17 (6 ULg)
Full Text
See detailL'explication en Ethologie : quelques essais de modélisation - L'exemple des poissons.
Poncin, Pascal ULg; Ruwet, J. C.

in Probio revue (1992), 10(1-2), 71-82

Detailed reference viewed: 17 (2 ULg)
Peer Reviewed
See detailLéonard Defrance, l'Émulation de Liège et l'Esprit des journaux
Droixhe, Daniel ULg

in Revue Belge d'Archéologie et d'Histoire de l'Art (1992), 61

Detailed reference viewed: 35 (1 ULg)
Peer Reviewed
See detailEvaluation des méthodes de contrôle des anabolisants dans le cadre des décisions européennes
Willemart, Jean-Pierre; Scippo, Marie-Louise ULg; Gaspar, Pol et al

in Annales de Médecine Vétérinaire (1992), 136

Detailed reference viewed: 15 (0 ULg)
Peer Reviewed
See detailAge differences in putting names and occupations to faces ?
Bruyer, R.; Van der Linden, Martial ULg; Lodewijck, M. et al

in Archives de Psychologie (1992), 60

Detailed reference viewed: 23 (10 ULg)
Full Text
Peer Reviewed
See detailGenes involved in tumor invasion and metastasis are differentially modulated by estradiol and progestin in human breast-cancer cells.
van den Brule, F. A.; Engel, J.; Stetler-Stevenson, W. G. et al

in International Journal of Cancer = Journal International du Cancer (1992), 52(4), 653-7

Invasion of basement membranes by cancer cells is a critical step in metastasis, which requires the coordinated expression of specific genes such as laminin receptors and metalloproteinases. Estradiol and ... [more ▼]

Invasion of basement membranes by cancer cells is a critical step in metastasis, which requires the coordinated expression of specific genes such as laminin receptors and metalloproteinases. Estradiol and progesterone modulate the clinical progression of steroid-sensitive breast cancers; however, little is known about the molecular regulation of the invasive phenotype by these hormones. We therefore examined the effects of 10 nM estradiol and/or 10 nM progestin R5020 on the expression of 2 non-integrin laminin binding proteins, the 67-kDa laminin receptor (67LR) and HLBP31 as well as the 72-kDa type-IV collagenase (MMP-2) and its inhibitor, TIMP-2, in steroid-receptor-positive (T47D and MCF-7) and -negative (MDA-MB 231) human breast-cancer cells. The relative steady-state level of 67LR mRNA was increased 2- to 3-fold by estradiol in both MCF-7 (p < 0.001) and T47D (p < 0.001) cells, also by R5020, alone or in combination with estradiol, in T47D cells (p < 0.001) and to a much less extent in MCF-7 cells. HLBP31 mRNA and protein levels were increased 2- to 3-fold (p < 0.001) by R5020 alone or in combination with estradiol, but not by estradiol alone. None of the steroid treatments affected the expression or activity of MMP-2. Interestingly, however, TIMP-2 mRNA levels and protein expression in MCF-7 and T47D cells were 50% down-regulated (p < 0.001) by treatment with R5020 or R5020 plus estradiol, but not by treatment with estradiol alone. None of these genes were modulated in steroid-independent MDA-MB231 cells. The data suggest that estradiol and progesterone might act as coordinators regulating specific genes in the steroid-sensitive breast-cancer cell, leading to the acquisition of the metastatic phenotype. [less ▲]

Detailed reference viewed: 15 (0 ULg)
Peer Reviewed
See detailUltrastructural detection of DNA within the nucleolus by sensitive molecular immunocytochemistry.
Thiry, Marc ULg

in Experimental Cell Research (1992), 200(1), 135-44

This paper describes a new technique for locating DNA on semithin or ultrathin sections of aldehyde-fixed and plastic-embedded cells or tissues. Sections were incubated in a medium containing ... [more ▼]

This paper describes a new technique for locating DNA on semithin or ultrathin sections of aldehyde-fixed and plastic-embedded cells or tissues. Sections were incubated in a medium containing bromodeoxyuridine (BUdR) triphosphate and terminal deoxynucleotidyltransferase. The labeled nucleotides bound at the surface of the sections were subsequently detected with an anti-BUdR antibody and immunoglobulin-gold complex. On semithin sections, labeled nucleotide detection was achieved by an amplification step with silver enhancement. This technique was applied to a wide variety of biological materials allowing a sensitive detection of DNA-containing structures, even where these are present in very low amounts. Examples of high resolution and sensitive detection include the DNA present in mitochondria, chloroplasts, mycoplasmas, and DNA viruses. Special attention focused on the location of DNA inside the nucleolus. In Ehrlich tumor cell nucleoli, DNA was detected in the fibrillar centers and not in the dense fibrillar component. Identical results were found in the nucleoli of other cell types. These results contradict earlier data but conform with other recent immunocytochemical observations concerning the correlation between structure and function in the nucleolus. This method provides a useful tool for investigations requiring highly precise correlations between a molecular function and a given ultrastructural morphology. [less ▲]

Detailed reference viewed: 11 (0 ULg)
Peer Reviewed
See detailLigands and tracers for PET studies of the 5-HT system--current status.
Crouzel, C.; Guillaume, Marcel ULg; Barre, L. et al

in International Journal of Radiation Applications and Instrumentation. Part B : Nuclear Medicine and Biology (1992), 19(8), 857-70

The status of the radiochemical development and biological evaluation of radioligands and tracers for PET studies of the serotonergic system is reviewed, indicating those agents with present value and ... [more ▼]

The status of the radiochemical development and biological evaluation of radioligands and tracers for PET studies of the serotonergic system is reviewed, indicating those agents with present value and those with future potential. Practical recommendations are given for the preparation of two useful radioligands for PET studies of central 5-HT2 receptors, namely [18F]setoperone and [18F]altanserin. Though, it has not proved possible to recommend tracers or radioligands for the study of other aspects of serotonergic system, prospects for future radiochemical development are indicated, especially for developing radioligands for the 5-HT re-uptake site, and for the 5-HT1 and 5-HT3 receptors. [less ▲]

Detailed reference viewed: 16 (0 ULg)
Peer Reviewed
See detailTnf-Alpha and Radiation-Induced Thymic Lymphomas
Boniver, Jacques ULg; Humblet, Chantal ULg; Delvenne, Philippe ULg et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (1992), 6(Suppl 3), 83-84

Detailed reference viewed: 9 (3 ULg)
See detailStudy of a new presumed mitochondrial carrier, the product of the yeast RIM 2 gene
Hellin, E.; Van Dyck, E.; Duyckaerts, Claire ULg et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

Detailed reference viewed: 16 (1 ULg)
Peer Reviewed
See detailLaminin and 67 Kd Laminin Binding Protein in Mouse B16 Melanoma Cells and 3t3 Fibroblast Spheroids
Siwek, B. L.; Munaut, Carine ULg; Bonjean, K. A. et al

in Anticancer Research (1992), 12(6B, Nov-Dec), 2011-6

Multicellular spheroids which promote cell-cell and cell-matrix interactions were prepared in culture with mouse B16 melanoma cells (pigmented or non pigmented) alone or mixed with mouse 3T3 fibroblasts ... [more ▼]

Multicellular spheroids which promote cell-cell and cell-matrix interactions were prepared in culture with mouse B16 melanoma cells (pigmented or non pigmented) alone or mixed with mouse 3T3 fibroblasts. Their volume and proliferation or necrosis rate were evaluated. As measured by dot blot immunoassay, laminin was mainly produced by fibroblasts rather than by melanoma cells. High levels of laminin B1 chain mRNA were detected only in spheroids composed of 3T3 fibroblasts. The levels of 67 kD laminin binding protein mRNA were high in all cell populations studied here. [less ▲]

Detailed reference viewed: 30 (3 ULg)
Full Text
Peer Reviewed
See detailNouvelles méthodes de lutte
Schiffers, Bruno ULg; Copin, Alfred; Roland, Liliane

in Revue de l'Agriculture (1992), Hors série

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailMiddle Devonian to Lower Carboniferous miospore stratigraphy in the Central Parnaiba Basin (Brazil)
Loboziak, S; Streel, Maurice ULg; Caputo, M.V. et al

in Annales de la Société Géologique de Belgique (1992), 115(1), 215-226

Detailed reference viewed: 10 (1 ULg)
See detailMolecular characterization of varicella-zoster virus gene expression
Defechereux, Patricia; Baudoux, Laurence; Jackers, Pascale ULg et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

Detailed reference viewed: 9 (2 ULg)
Full Text
Peer Reviewed
See detailHémorragies cérébro-méningées par rupture d'anévrysme artériel intracrânien
Pirotte, B.; Born, JD.; HANS, Pol ULg et al

in Revue Médicale de Liège (1992), 18

Detailed reference viewed: 12 (1 ULg)
Peer Reviewed
See detailLymphocyte activation and the family of NF-kappa B transcription factor complexes.
Bours, Vincent ULg; Franzoso, G.; Brown, K. et al

in Current Topics in Microbiology and Immunology (1992), 182

Detailed reference viewed: 6 (2 ULg)
Peer Reviewed
See detailFibronectin Promotes Lung Colony Formation in the Mouse by B16 Melanoma Cells Spheroids
Coucke, P.; Gillet, Marie-Claire ULg; de Leval, Laurence ULg et al

in In Vivo (Athens, Greece) (1992), 6(5, Sep-Oct), 481-6

By microscopical observation and using an original method of automatic image analysis, we studied on histological sections the rate of lung colony formation after intravenous injection into the mouse of ... [more ▼]

By microscopical observation and using an original method of automatic image analysis, we studied on histological sections the rate of lung colony formation after intravenous injection into the mouse of B16 melanoma cells previously cultivated in vitro as pure or mixed spheroids (B16 + 3T3 fibroblasts). The preincubation in vitro of pure spheroids with fibronectin significantly increased the percentages of lung section area occupied by tumors and the relative number of internal lung colonies. This effect of fibronectin was even more obvious when mixed spheroids were injected. [less ▲]

Detailed reference viewed: 12 (2 ULg)
Full Text
Peer Reviewed
See detailTranscriptional regulation by triiodothyronine requires synergistic action of the thyroid receptor with another trans-acting factor
Voz, Marianne ULg; Peers, Bernard ULg; Wiedig, Murielle J et al

in Molecular & Cellular Biology (1992), 12(9), 3991-7

Human placental lactogen B (hCS-B) promoter activity is strongly stimulated by triiodothyronine (T3) in pituitary GC cells through interaction between the thyroid receptor and a thyroid receptor-binding ... [more ▼]

Human placental lactogen B (hCS-B) promoter activity is strongly stimulated by triiodothyronine (T3) in pituitary GC cells through interaction between the thyroid receptor and a thyroid receptor-binding element (TBE) spanning coordinates -67 to -41. This TBE is adjacent to the binding site for pituitary factor GHF1 (-95 to -68) which seems necessary for T3 stimulation of hCS-B promoter activity (M. L. Voz, B. Peers, A. Belayew, and J. A. Martial, J. Biol. Chem. 266:13397-13404, 1991). We here demonstrate actual synergy between the thyroid receptor and GHF1. Indeed, in placental JEG-3 cells devoid of factor GHF1, hCS promoter activity is barely stimulated by T3, while a strong response is observed in pituitary GC cells. In the latter, furthermore, neither the TBE nor the GHF1-binding site alone is sufficient to render the thymidine kinase promoter responsive to T3, while in combination they promote strong T3 stimulation. Close proximity between these sites is required for optimal synergy: T3 stimulation globally decreases with increased spacing. Furthermore, synergy occurs not only with a GHF1-binding site but also with all other factor recognition sequences tested (Sp1, NF1, CP1, Oct1, and CACCC boxes) and even with two other copies of the TBE. Nor is it specific to hCS TBE, since the palindromic sequence TCAGGTCA TGACCTGA (TREpal) also exhibits cooperativity. [less ▲]

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailLocindus, le jeu de la localisation industrielle
Merenne-Schoumaker, Bernadette ULg; Bianchet, Bruno; Demeuse, Yves

in Bulletin de la Société Géographique de Liège (1992), (28), 41-56

Any location decision takes into account many variables and processes. In order to apprehend them, we propose a "simulation game". Indeed, this one presents the great merit of putting the student in a ... [more ▼]

Any location decision takes into account many variables and processes. In order to apprehend them, we propose a "simulation game". Indeed, this one presents the great merit of putting the student in a problematic situation and leads him to understand certain attitudes. However, a good finality information, and on the other hand, a fundamental learning. Theoretical knowledge so envisaged will permit a better understanding of the decision process and will improve its efficency. [less ▲]

Detailed reference viewed: 50 (0 ULg)
Peer Reviewed
See detailDynamic changes in the density of radial glial fibres of the developing murine cerebral wall: A quantitative immunohistochemical analysis
Gadisseux, Jean-François; Evrard, Phlippe; Misson, Jean-Paul ULg et al

in Journal of Comparative Neurology (The) (1992), 321

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailAperçu de la qualité du bois de Chêne rouge d'Amérique
Jourez, Benoît ULg; Leclercq, André

in Bulletin des Recherches Agronomiques de Gembloux (1992), 27(3), 309-325

Detailed reference viewed: 13 (0 ULg)
Peer Reviewed
See detailExpression de l'antigene DRC1 par les cellules leucemiques.
Antoine, Nadine ULg; Beckers, Catherine ULg; Marcoty, C. et al

in Revue Médicale de Liège (1992), 47(2), 95-9

Detailed reference viewed: 28 (9 ULg)
Full Text
Peer Reviewed
See detailCan perturbative QCD predict a substantial part of diffractive LHC / SSC physics?
Cudell, Jean-René ULg; Margolis, B.

in Physics Letters B (1992), 297

Detailed reference viewed: 16 (1 ULg)
Peer Reviewed
See detailDaily-life difficulties in person recognition reported by young and elderly subjects
Schweich, M.; Van der Linden, Martial ULg; Brédart, Serge ULg et al

in Applied Cognitive Psychology (1992), 6

Detailed reference viewed: 16 (2 ULg)
Peer Reviewed
See detailSIMULATION OF FAST TRANSIENTS IN FLUID TRANSPORT EQUIPMENTS AND UTILITY NETWORKS
Heyen, Georges ULg; Kalitventzeff, Boris ULg; HUTCHINSON, Philip et al

in Computers & Chemical Engineering (1992), 16(Suppl. S), 109-117

A model allowing dynamic simulation of processes involving compression, expansion, heat generation and transfer in fluids is presented. Equations are developed for some equipment models, based on one ... [more ▼]

A model allowing dynamic simulation of processes involving compression, expansion, heat generation and transfer in fluids is presented. Equations are developed for some equipment models, based on one-dimensional flow approximation. The architecture of a simulation package based on the object paradigm is described. The programme has been validated with experimental data : surge onset in compression systems has been satisfactorily predicted. [less ▲]

Detailed reference viewed: 11 (0 ULg)
Peer Reviewed
See detailWhere, within the nucleolus, are the rRNA genes located?
Thiry, Marc ULg; Goessens, Guy ULg

in Experimental Cell Research (1992), 200(1), 1-4

Detailed reference viewed: 6 (0 ULg)
Peer Reviewed
See detailIdentification of orphan G protein-coupled receptors
Vassart, G.; Parmentier, M.; Libert, M. et al

in Clinical Neuropharmacology (1992), 15

Detailed reference viewed: 6 (3 ULg)
See detailVaricella-zoster gene 63 encoded protein is an important regulatory factor
Jackers, Pascale ULg; Defechereux, Patricia; Baudoux, Laurence et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

Detailed reference viewed: 24 (8 ULg)
Peer Reviewed
See detailClinical Neurophysiology Studies in Headache: A Review of Data and Pathophysiological Hints
Schoenen, Jean ULg

in Functional Neurology (1992), 7(3, May-Jun), 191-204

In migraine between attacks EMG studies are normal. Recordings during attacks need to be performed. Temporalis exteroceptive silent period is useful in the differential diagnosis of headaches and sheds ... [more ▼]

In migraine between attacks EMG studies are normal. Recordings during attacks need to be performed. Temporalis exteroceptive silent period is useful in the differential diagnosis of headaches and sheds some light on the pathophysiology of tension-type headache. [less ▲]

Detailed reference viewed: 17 (0 ULg)
See detailHuman papillomavirus type 33 upstream regulatory elements can control gene expression in human cervical keratinocytes
Lauricella-Lefèbvre, M. A.; Rentier, Bernard ULg; Piette, Jacques ULg

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

Detailed reference viewed: 5 (2 ULg)
Peer Reviewed
See detailPotentialites des tests ELISA pour l'analyse qualitative et quantitative de pesticides dans l'environment: application au cas de l'isoproturon.
Portetelle, Daniel ULg; Liegeois, E.; Dehon, Y. et al

in Bulletin des Recherches Agronomiques de Gembloux (1992), 27(1),

Detailed reference viewed: 16 (1 ULg)
Peer Reviewed
See detailHighly sensitive immunodetection of DNA on sections with exogenous terminal deoxynucleotidyl transferase and non-isotopic nucleotide analogues.
Thiry, Marc ULg

in Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society (1992), 40(3), 411-9

A new method is described for locating DNA on ultra-thin sections. Sections of aldehyde-fixed, plastic-embedded cells were incubated in a medium containing terminal deoxynucleotidyl transferase (TdT) and ... [more ▼]

A new method is described for locating DNA on ultra-thin sections. Sections of aldehyde-fixed, plastic-embedded cells were incubated in a medium containing terminal deoxynucleotidyl transferase (TdT) and various non-isotopic nucleotide analogues. The labeled nucleotides bound to the surface of ultra-thin sections were then visualized by an indirect immunogold labeling technique. The resulting labeling pattern was strongly dependent on the divalent cation used in the TdT medium. The method revealed with great precision the specific DNA-containing structures within Ehrlich tumor cells, even where DNA was present in very low amounts. The method is compatible with all usual fixation and embedding procedures and can be combined with cytochemical methods. The in situ TdT method provides a very useful tool for pinpointing the precise location of DNA within biological material at the ultrastructural level. [less ▲]

Detailed reference viewed: 5 (0 ULg)
Full Text
Peer Reviewed
See detailContribution à la mise au point d'un dispositif de culture associée cotonnier-niébé dans la région de Gandajika au Zaïre
Delhove, G.; Mergeai, Guy ULg; Mulamba, K.

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), (35), 375-378

Detailed reference viewed: 1 (0 ULg)
See detailMatériaux pour enseigner l'histoire des femmes
Jadoulle, Jean-Louis ULg

in Histoire et Enseignement : Bulletin (1992), 42e année(n°3), 21-23

Detailed reference viewed: 4 (0 ULg)
Peer Reviewed
See detailMaillard reaction products and lysoalanine: urinary excretion and the effects on kidney fraction of preterm infants fed head processed milk formula
Battisti, Oreste ULg; Langhendries, J. P.; Hurell, R. F. et al

in Journal of Pediatric Gastroenterology and Nutrition (1992), 14

Detailed reference viewed: 27 (0 ULg)
Peer Reviewed
See detailReplicon typing of virulence plasmids of enterotoxigenic Escherichia coli isolates from cattle
Mainil, Jacques ULg; Bex, F.; Dreze, P. et al

in Infection and Immunity (1992), 60

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detailRevision of the structure of strychnofluorine, an alkaloid of Strychnos gossweileri
Quetin-Leclercq, Joëlle; Coune, Claude; Delaude, Clément et al

in Phytochemistry (1992), 31(12), 4347-4349

The structure of strychnofluorine, an indole alkaloid isolated in 1980 from the root bark of Strychnos gossweileri, has been revised. Strychnofluorine proved to be identical with 18 ... [more ▼]

The structure of strychnofluorine, an indole alkaloid isolated in 1980 from the root bark of Strychnos gossweileri, has been revised. Strychnofluorine proved to be identical with 18-hydroxynorfluorocurarine that has been isolated as a minor (contaminated) alkaloid from Strychnos ngouniensis in 1983. [less ▲]

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailChiral theory of mesons in dense baryonic matter (I)
Jaminon, Martine ULg; Mendez Galain, Ramon; Ripka, Georges et al

in Nuclear Physics A (1992), 537

Detailed reference viewed: 7 (1 ULg)
Peer Reviewed
See detailPhosphorus intake in preterm babies and variation of tubular reabsorption for phosphate per liter glomerular filtrate
Battisti, Oreste ULg; Langhendries, J. P.; François, A. et al

in Biology of the Neonate (1992), 61

Detailed reference viewed: 15 (3 ULg)
Full Text
Peer Reviewed
See detailEnergy hypersurface local properties of the O2HF-1 rearrangement
Dive, Georges ULg; Dehareng, Dominique ULg; Culot, Patrick et al

in Chemical Physics Letters (1992), 195(2-3), 189-193

This work analyses a case where Murrell's proposal, stating that a second-order point must lie above a first-order one, is apparently violated. Study at the SCF-UMP2 level within the D95 + + basis set, of ... [more ▼]

This work analyses a case where Murrell's proposal, stating that a second-order point must lie above a first-order one, is apparently violated. Study at the SCF-UMP2 level within the D95 + + basis set, of one critical point of the O2HF- anion, previously proposed to be of order two by Lopez, shows the importance of the electronic correlation. The critical point associated with the (2)PI first-order ones. The present analysis reveals that this contradistinction can be explained by three unconsidered elements: the local symmetry, the electronic correlation and the internal variables description. [less ▲]

Detailed reference viewed: 19 (2 ULg)
Full Text
Peer Reviewed
See detailPalynological data from the Devonian-Carboniferous boundary beds in the new Stockum trench II and the Hasselbachtal borehole, northern Rhenish Massif, Germany
Higgs, K; Streel, Maurice ULg; Korn, D et al

in Annales de la Société Géologique de Belgique (1992), 115(2), 551-557

Detailed reference viewed: 14 (1 ULg)
Peer Reviewed
See detailEtude ultrastructure de l'organisation du nucléoïde du virus de la varicelle et du zona
Schoonbroodt, Sonia; Piette, Jacques ULg; Rentier, Bernard ULg

in Bulletin de la Société Royale des Sciences de Liège (1992), 60(6), 373-383

Detailed reference viewed: 21 (0 ULg)
Full Text
Peer Reviewed
See detailOn Relativistic Scalar and Vector-Mesons with Harmonic Oscillator-Like Interactions
Debergh, N.; Ndimubandi, J.; Strivay, David ULg

in Zeitschrift Fur Physik C-Particles and Fields (1992), 56(3), 421-425

Relativistic descriptions for spin 0 and 1 particles of nonzero restmasses are known for a long time as the so-called Kemmer or Sakata-Taketani formulations. Through harmonic oscillatorlike interactions ... [more ▼]

Relativistic descriptions for spin 0 and 1 particles of nonzero restmasses are known for a long time as the so-called Kemmer or Sakata-Taketani formulations. Through harmonic oscillatorlike interactions, we study the nonrelativistic limit of the corresponding wave equations in connection with expected spin-orbit terms. Typical Foldy-Wouthuysen developments are included in these approaches with exact results up to required orders for interacting vector mesons only. [less ▲]

Detailed reference viewed: 11 (0 ULg)
Peer Reviewed
See detailA novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site.
Bours, Vincent ULg; Burd, P. R.; Brown, K. et al

in Molecular & Cellular Biology (1992), 12(2), 685-95

A Rel-related, mitogen-inducible, kappa B-binding protein has been cloned as an immediate-early activation gene of human peripheral blood T cells. The cDNA has an open reading frame of 900 amino acids ... [more ▼]

A Rel-related, mitogen-inducible, kappa B-binding protein has been cloned as an immediate-early activation gene of human peripheral blood T cells. The cDNA has an open reading frame of 900 amino acids capable of encoding a 97-kDa protein. This protein is most similar to the 105-kDa precursor polypeptide of p50-NF-kappa B. Like the 105-kDa precursor, it contains an amino-terminal Rel-related domain of about 300 amino acids and a carboxy-terminal domain containing six full cell cycle or ankyrin repeats. In vitro-translated proteins, truncated downstream of the Rel domain and excluding the repeats, bind kappa B sites. We refer to the kappa B-binding, truncated protein as p50B by analogy with p50-NF-kappa B and to the full-length protein as p97. p50B is able to form heteromeric kappa B-binding complexes with RelB, as well as with p65 and p50, the two subunits of NF-kappa B. Transient-transfection experiments in embryonal carcinoma cells demonstrate a functional cooperation between p50B and RelB or p65 in transactivation of a reporter plasmid dependent on a kappa B site. The data imply the existence of a complex family of NF-kappa B-like transcription factors. [less ▲]

Detailed reference viewed: 3 (1 ULg)
Full Text
Peer Reviewed
See detailNa+,2Cl-,K+ cotransport system as a marker of antihypertensive activity of new torasemide derivatives
Masereel, B.; Ferrari, P.; Ferrandi, M. et al

in European Journal of Pharmacology (1992), 219

Detailed reference viewed: 10 (1 ULg)
Peer Reviewed
See detailIncidence redistributive de la privatisation des retraites
Delhausse, B.; Pestieau, Pierre ULg; Perelman, Sergio ULg

in Revue d'Economie Financière (1992), (23), 65-79

L’objet de cet article est d’étudier l’incidence redistributive que devrait avoir la substitution partielle des pensions publiques par des pensions privées, qui favorisent les salaires et les revenus les ... [more ▼]

L’objet de cet article est d’étudier l’incidence redistributive que devrait avoir la substitution partielle des pensions publiques par des pensions privées, qui favorisent les salaires et les revenus les plus élevés relativement aux salaires et revenus les plus faibles. Dans la mesure où les pensions privées vont se développer, l’article évalue si elles ne vont pas accroître les inégalités dans les tranches d’âge les plus élevées par des simulations effectuées dans le cadre de la Belgique. [less ▲]

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailPermeability of the Endothelium and Partitioning of the Pulmonary Blood Flow Resistance in Isolated Perfused Pig Lungs: Effects of Breed and Age
Gustin, Pascal ULg; Urbain, B.; Delaunois, Annie et al

in Veterinary Research Communications (1992), 16(1), 69-82

The right and left lungs of 5 healthy Minipigs and of 13 healthy Landrace piglets were isolated, perfused at constant pressure and maintained in an isogravimetric state under zone III conditions ... [more ▼]

The right and left lungs of 5 healthy Minipigs and of 13 healthy Landrace piglets were isolated, perfused at constant pressure and maintained in an isogravimetric state under zone III conditions (pulmonary venous pressure greater than alveolar pressure). By applying the double, arterial and venous, occlusion technique, the total blood flow resistance (R) was partitioned into four components: arterial (Ra), pre- (Ra') and post-capillary (Rv') and venous (Rv). The capillary filtration coefficient (Kf,c) was evaluated by measuring the weight gained by the lungs when the arterial and venous pressures were suddenly increased. In the youngest Landrace piglets (5 weeks old), there was an uncontrolled vasoconstriction which sometimes prevented perfusion of the lungs and induced a large increase in Rt. These high values of Rt were decreased by tolazoline administration. The values of Rt recorded in older pigs (12-13 weeks old) were lower in Minipigs (33.66 +/- 3.77 cmH2O min L-1 per 100 g of lungs; n = 5) than in Landrace piglets (55.20 +/- 6.18 cmH2O min L-1 per 100 g; n = 5). This breed difference was due to the differences in Ra' and Rv'. The mean values of Kf,c were 0.193 +/- 0.015 and 0.202 +/- 0.029 ml min (cmH2O)-1 per 100 g of the lungs in Minipigs and Landrace piglets respectively. All these parameters were stable for the 3 hours following the equilibrium period. It was concluded that: (1) There is an age-related maturation of the control of the vasomotor tone in porcine lungs. (2) Pulmonary microvascular haemodynamics are influenced by the breed of the pigs. (3) There was no difference in the Kf,c values between both the breeds. (4) A comparison of the values reported for dogs and rabbits with our data shows that the pre- and post-capillary resistances and, to a lesser extent, the arterial and venous resistances are relatively high in pigs [less ▲]

Detailed reference viewed: 5 (1 ULg)
Peer Reviewed
See detailA fully coupled elastoplastic damage modeling and fracture criteria in metalforming processes
Zhu, Y. Y.; Cescotto, Serge ULg; Habraken, Anne ULg

in Journal of Materials Processing Technology (1992), 32

Detailed reference viewed: 30 (3 ULg)
Peer Reviewed
See detailThe thymic repertoire of neuroendocrine self antigens and the central immune tolerance of neuroendocrine functions
Geenen, Vincent ULg; Cormann, Nadine; Robert, Françoise et al

in European Journal of Medicine (The) (1992), 1(3), 158-165

Detailed reference viewed: 13 (3 ULg)
Full Text
Peer Reviewed
See detailThe interaction between Bovine Leukemia Virus and its target cell.
Burny, Arsène; Kettmann, Richard ULg; Willems, Luc ULg et al

in AIDS Research and Human Retroviruses (1992), 8

Previous results indicate that the external glycoprotein gp51 of bovine leukemia virus plays an important role in the process of cell fusion induced by bovine leukemia virus (Bruck, C., Mathot, S ... [more ▼]

Previous results indicate that the external glycoprotein gp51 of bovine leukemia virus plays an important role in the process of cell fusion induced by bovine leukemia virus (Bruck, C., Mathot, S., Portetelle, D., Berte, C., Franssen, J. D., Herion, P., and Burny, A. (1982) Virology 122, 342-352; Voneche, V., Portetelle., D., Kettmann, R., Willems, L., Limbach, K., Paoletti, E., Ruysschaert, J. M., Burny, A., and Brasseur, R. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 3810-3814) and suggest that a region encompassing residues 23 and 25 of gp51 is involved in this process (Portetelle, D., Couez, D., Bruck, C., Kettmann, R., Mammerickx, M., Van der Maaten, M., Brasseur, R., and Burny, A. (1989) Virology 169, 27-33; Mamoun, R., Morisson, M., Rebeyrotte, N., Busetta, B., Couez, D., Kettmann, R., Hospital, M., and Guillemain, B. (1990) J. Virol. 64, 4180-4188). X-ray diffraction studies performed on envelope glycoproteins of influenza virus indicate that the NH2-terminal part of the external glycoprotein lies very close to the fusion peptide. The same overall structure seems to exist in human immunodeficiency virus as suggested by site-directed mutagenesis followed by syncytia induction assays. Our theoretical studies indicate that a segment expanding between residues 19 and 27 of gp51 probably adopts an amphipathic beta-strand structure. We hypothesize that the amphipathic 19-27 structure of gp51 plays an important role in the process of membrane fusion by interacting with the fusion peptide or with another region of gp30. Mutational analysis disrupting the amphipathy of the 19-27 region strongly altered the fusogenic capacity of the gp51-gp30 complex. [less ▲]

Detailed reference viewed: 19 (4 ULg)
Full Text
Peer Reviewed
See detailExpert system : a versatile tool for the real time control of a solar building
Nicolas, Jacques ULg; Andre, Philippe ULg

in Journal on automatic control (1992), 33(3), 99-105

The expert-system approach is well suited to manage complexes heating systems, with various energy sources and different possible strategies of heating or cooling. A specific computer tool is applied on ... [more ▼]

The expert-system approach is well suited to manage complexes heating systems, with various energy sources and different possible strategies of heating or cooling. A specific computer tool is applied on the solar-assisted heat pump system of Fondation Universitaire Luxembourgeoise in Arlon. It is developed around a list of rules of the type : "if…then.." and the code is written in Prolog language. The main difficulty of implementing such tool is the managing of time, because every sensor or actuator reacts in real time and a decision has first to be tested and validated before issuing on-line action on the system. The main advantage of the approach is that expert-system can very easily encapsulate the experimental knowledge of the heating system manager, simply by adding some rules in the rule base. [less ▲]

Detailed reference viewed: 39 (0 ULg)
Peer Reviewed
See detailIron content in human alveolar macrophages.
CORHAY, Jean-Louis ULg; Weber, Georges ULg; Bury, Thierry ULg et al

in European Respiratory Journal (1992), 5(7), 804-9

Intracellular iron can be estimated semi-quantitatively by histochemical determination using the ferrocyanide reagent's score. Particle-induced X-ray emission (PIXE) allows accurate determination of ... [more ▼]

Intracellular iron can be estimated semi-quantitatively by histochemical determination using the ferrocyanide reagent's score. Particle-induced X-ray emission (PIXE) allows accurate determination of various elements including iron in cells and biological fluids. Both techniques have been used to measure iron in alveolar macrophages gathered by bronchoalveolar lavage. The purpose of this study was to investigate the clinical usefulness of the PIXE technique in occupational respiratory medicine and in various pulmonary diseases. Using the PIXE method, we measured the iron content of alveolar macrophages in healthy subjects, with and without occupational exposure to iron dust, and in patients with pulmonary diseases (chronic obstructive pulmonary disease (COPD), lung cancer, Goodpasture's syndrome). Our results were then compared with those obtained with the ferrocyanide reagent. Intramacrophagic iron was 0.33 +/- 0.21 micrograms.10(-6) (mean +/- SD) cells in healthy non-smoking subjects without occupational exposure. Intramacrophagic iron was increased in smokers, iron-steelworkers, and in patients with COPD or lung cancer even in the absence of pulmonary haemorrhage. The two patients with Goodpasture's syndrome had high intramacrophagic iron content. About 80% of the whole bronchoalveolar lavage fluid iron content was in the cells. Mean iron content of blood monocytes, lymphocytes and neutrophils of eight healthy subjects was significantly lower than that of alveolar macrophages. A significant correlation was found between iron determination by the PIXE method and the ferrocyanide reagent's score (r = 0.89). We conclude that intramacrophagic iron may be increased in steelworkers and subjects with pulmonary haemorrhage, but also in asymptomatic smokers, in COPD and lung cancer patients without occupational exposure to iron dust. [less ▲]

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailAlphonse Allais : fumisterie littéraire
Defays, Jean-Marc ULg

in Romantisme (1992), (75), 27-34

Detailed reference viewed: 22 (1 ULg)
Full Text
See detailUn Coran liégeois
Martin, Aubert ULg; Bauden, Frédéric ULg

in La Vie Wallonne (1992), 56(417-418), 5-20

Detailed reference viewed: 74 (18 ULg)
Peer Reviewed
See detailThe thermospheric odd nitrogen photochemistry: role of non thermal N(4S) atoms
Shematovich, V.; Bisikalo, D.; Gérard, Jean-Claude ULg

in Geophysical Research Letters (1992), 10

Detailed reference viewed: 6 (1 ULg)
Peer Reviewed
See detailBrachiocephalic Arterial Reconstruction
VAN DAMME, Hendrik ULg; Caudron, D.; Defraigne, Jean-Olivier ULg et al

in Acta Chirurgica Belgica (1992), 92(1), 37-45

From 1980 to 1990, 18 patients underwent trans-sternal repair for occlusive disease of the brachiocephalic artery. The mean age was 57 years (43-72). Most of the patients were women (n = 10). All but two ... [more ▼]

From 1980 to 1990, 18 patients underwent trans-sternal repair for occlusive disease of the brachiocephalic artery. The mean age was 57 years (43-72). Most of the patients were women (n = 10). All but two patients had one or more symptoms related to the stenosis of the brachiocephalic trunk: right-sided upper limb ischemia (n = 7), transient ischemic attacks (n = 8), vertebrobasilar insufficiency (n = 6), left sided minor stroke (n = 1). Only two patients were asymptomatic before operation. Angiography revealed a tight stenosis (n = 14) or an occlusion (n = 3); in one patient it concerned an ulcerated non-stenotic plaque of the brachiocephalic artery. Eleven patients had coexistent involvement of other supraaortic vessels. Angiographically, clinically and intraoperatively, there was evidence of Takayasu arteritis in three female patients. All patients had direct repair by trans-sternal approach. Six patients with short lesions had thromboendarterectomy with patch angioplasty of the innominate artery. In eleven cases, aorto-brachiocephalic bypass grafting was performed. In one patient, aortic calcification precluded proximal anastomosis, and a carotid-to-carotid bypass was done. In five patients, simultaneous revascularization of subclavian (n = 3), left common carotid (n = 2) or internal carotid artery (n = 2) completed the procedure. In one patient, concomitant coronary revascularization was done. There was no operative mortality. Postoperative morbidity was limited to pulmonary infection (n = 2), transient neurologic deficit (n = 1) and renal insufficiency (n = 1). All patients had relief of symptoms. Duplex echo scan confirmed patency of all reconstructions at a mean follow-up of 46 months.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailExpression of members of the putative olfactory receptor gene family in mammalian germ cells.
Parmentier, M.; Libert, F.; Schurmans, Stéphane ULg et al

in Nature (1992), 355

A series of genomic and complementary DNA clones encoding new putative members of G protein-coupled receptors were isolated using homology cloning and low-stringency polymerase chain reaction. Among the ... [more ▼]

A series of genomic and complementary DNA clones encoding new putative members of G protein-coupled receptors were isolated using homology cloning and low-stringency polymerase chain reaction. Among the unidentified receptors ('orphan receptors'), a human genomic clone (HGMP07) was characterized by the presence of its transcripts in the testis and by its belonging to a large subfamily of genes sharing extensive sequence similarities. Sequence comparison demonstrated that this gene subfamily is the human counterpart of the putative rat olfactory receptors cloned recently. Another 48 members of the family were cloned. Northern blotting further demonstrated the presence of olfactory receptor transcripts in germ cells. Our finding suggests that a common receptor gene family encodes olfactory receptors and sperm cell receptors that could be involved in chemotaxis during fertilization [less ▲]

Detailed reference viewed: 21 (5 ULg)
Full Text
Peer Reviewed
See detailPour une pragmatique du discours comique
Defays, Jean-Marc ULg

in Revue Romane (1992), (27-2), 250-265

Detailed reference viewed: 46 (0 ULg)
Peer Reviewed
See detailMicroporosimétrie quantitative de roches et matériaux par analyse d'images
Pirard, Eric ULg; Pierroux, Alain

in Annales de la Société Géologique de Belgique (1992), 115(1), 245-252

Detailed reference viewed: 31 (1 ULg)
Peer Reviewed
See detailAnalysis by in Situ Hybridization of Cells Expressing Mrna for Tumor-Necrosis Factor in the Developing Thymus of Mice
Deman, Johanne; Martin, M arie Thérèse; Delvenne, Philippe ULg et al

in Developmental Immunology (1992), 2(2), 103-9

We have used in situ hybridization to investigate the expression of TNF-alpha genes by thymic cells during fetal development in mice. In 14-day-old fetal thymuses, very scarce cells produce TNF-alpha mRNA ... [more ▼]

We have used in situ hybridization to investigate the expression of TNF-alpha genes by thymic cells during fetal development in mice. In 14-day-old fetal thymuses, very scarce cells produce TNF-alpha mRNA. A second phase of cytokine gene expression starts on day 16. The density of positive cells progressively increases up to day 20. Thymuses at 15 days of gestation and after birth do not express detectable cytokine mRNA. In an attempt to identify the nature of the TNF-alpha mRNA-producing cells, acid phosphatase activity, which is characteristic of the macrophage lineage, was studied in the same thymuses. Acid phosphatase-positive cells only appear on day 15. Their frequency increases up to birth. However, no correlation can be established between acid phosphatase--and TNF alpha mRNA--positive cells. The results indicate that a small subset of thymic cells is responsible for TNF-alpha mRNA production during ontogeny: These cells are not yet identified. The possible role of TNF-alpha in thymic ontogeny is discussed. [less ▲]

Detailed reference viewed: 14 (2 ULg)
Peer Reviewed
See detailIdentification of patients at high risk for recurrence of sustained ventricular tachycardia after healing of acute myocardial infarction.
Rodriguez, L M; Oyarzun, R; Smeets, J et al

in American Journal of Cardiology (1992), 69(5), 462-4

A prognostic index for nonfatal recurrences of ventricular tachycardia (VT) was developed using a retrospective analysis of a group of 206 patients with sustained monomorphic VT or ventricular ... [more ▼]

A prognostic index for nonfatal recurrences of ventricular tachycardia (VT) was developed using a retrospective analysis of a group of 206 patients with sustained monomorphic VT or ventricular fibrillation (VF) after healing of acute myocardial infarction. 74 patients (36%) (64 with VT and 10 with VF) had recurrences of sustained monomorphic VT during 3.4 +/- 9 years of follow-up. Three clinical variables were selected and weighted by stepwise logistic discriminant analysis of the study group. They were coded as follows: interval of myocardial infarction to arrhythmia (less than 2 months = 1; 2 to 6 months = 2; greater than 6 months = 3), drug therapy with or without sotalol (with = 1, without = 2), and VT or VF as the presenting arrhythmia (VT = 1, VF = 2). The prognostic index was: 3.41 - (0.56 x interval) - (1.94 x therapy) + (0.86 x arrhythmia). This index was validated prospectively in a test group of 158 consecutive patients with VT or VF after healing of acute myocardial infarction. Patients were allocated into different classes with decreasing prognostic index values associated with increasing risk for recurrences of VT. In the test group, 27 of 158 (17%) patients (22 with VT and 5 with VF) had recurrences of VT (follow-up of 2 +/- 2 years). Two risk classes of patients were identified: high risk for recurrences of VT (61%) corresponding to patients with a negative index; and low risk (4%) consisting of those with a positive index. Thus, using O as the cutoff point, the sensitivity, specificity, and positive and negative predictive values were 81, 89, 62 and 96%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

Detailed reference viewed: 9 (0 ULg)
Peer Reviewed
See detailComposition And Nutritive-Value For Rats Of Aspergillus-Niger Solid Fermented Barley
Mathot, Pierre; Debevere, Ch.; Walhain, Philippe et al

in Animal Feed Science & Technology (1992), 39(3-4), 227-237

Detailed reference viewed: 22 (0 ULg)
Peer Reviewed
See detailAltered Capillary Filtration Coefficient in Parathion- and Paraoxon-Induced Edema in Isolated and Perfused Rabbit Lungs
Delaunois, Annie; Gustin, Pascal ULg; Ansay, Michel

in Toxicology and Applied Pharmacology (1992), 116(2), 161-169

Changes in pulmonary endothelium permeability and in microvascular hemodynamics induced by parathion (Pth) and paraoxon (Pox), its active metabolite, were investigated in isolated, perfused rabbit lungs ... [more ▼]

Changes in pulmonary endothelium permeability and in microvascular hemodynamics induced by parathion (Pth) and paraoxon (Pox), its active metabolite, were investigated in isolated, perfused rabbit lungs. Blood-free perfusate was recirculated through isolated and ventilated lungs in an isogravimetric state and in zone III conditions. The arterial/venous/double occlusion technique was used to divide the total vascular resistance (Rt) into four components: arterial, precapillary, postcapillary, and venous. The capillary filtration coefficient (Kfc) was evaluated by measuring the amount of fluid filtering through the endothelium when the arterial and venous pressures were suddenly increased. Pth and Pox induced pulmonary edema by increasing endothelium permeability without changing the hemodynamic parameters at any level of the vascular bed. The Kfc value increased progressively, reaching a maximum (Emax) 60 min after administration of organophosphate (558 ± 65% (n = 5) and 707 ± 109% (n = 5) of baseline values, for Pth and Pox, respectively). During the next 60 min, it decreased. The time course of Pox-induced changes in Kfc was similar to that obtained with Pth. The concentration-response curve (Emax) expressed as a percentage of the baseline value versus the logarithm of the malor Pth concentration, ranging from 2 × 10−5 to 4 × 10−4 image) was linear (y = 1661.1 + 327.3x, R = 0.89, p < 0.001, N = 14). Piperonyl butoxide (4 × 10−4 image), an inhibitor of cytochrome P450, had a strong protective effect against Pth (4 × 10−4 image)-induced alterations of endothelium permeability (n = 5, p < 0.001). The effects of Pox (4 × 10−4 image) on Kfc were completely abolished by pretreatment with 10−5 image atropine, as shown by the significantly lower Emax value recorded in atropine-pretreated lungs (129 ± 33%, n = 4) than in Pox-treated lungs (707 ± 109%, n = 5, p < 0.001). The effects of Pth, on the other hand, were only partially inhibited, since the Emax value recorded in atropine-pretreated lungs (196 ± 20%, n = 4) remained significantly higher than that recorded for control lungs (129 ± 15%; n = 5; p < 0.05). These results show that isolated and perfused rabbit lungs constitute and appropriate model for studying the direct pulmonary effects of organophosphates. The edema-inducing action of Pth depends on its activation by conversion to Pox in the lung tissue. It can be explained by an increase in endothelium permeability. This effect is mediated principally by muscarinic receptors [less ▲]

Detailed reference viewed: 13 (0 ULg)
Peer Reviewed
See detailNew data concerning the functional organization of the mammalian cell nucleolus: detection of RNA and rRNA by in situ molecular immunocytochemistry.
Thiry, Marc ULg

in Nucleic Acids Research (1992), 20(23), 6195-200

We have investigated the fine spatial distribution of RNA and rRNA within the Ehrlich tumor cell nucleolus by in situ hybridization with a biotin-labeled probe and by two new strategies, the polyadenylate ... [more ▼]

We have investigated the fine spatial distribution of RNA and rRNA within the Ehrlich tumor cell nucleolus by in situ hybridization with a biotin-labeled probe and by two new strategies, the polyadenylate nucleotidyl transferase-immunogold technique and immuno-labeling with anti-RNA antibodies. Besides the presence, as expected, of RNA and rRNA in the granular component and the dense fibrillar component, we show, for the first time, significant label over all the fibrillar centers of the nucleoli. When RNA and DNA were detected simultaneously on the same sections, only the fibrillar centers were positive for both. These results throw light on the controversial subject of the precise location of transcribing rRNA genes within the nucleolus. The fibrillar centers, and not the dense fibrillar component, should thus be the site of rRNA synthesis. [less ▲]

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailAneurysm of the Ascending Aorta after Cardiac Transplantation
Defraigne, Jean-Olivier ULg; Vahdat, Olivier; LAVIGNE, Jean-Paul ULg et al

in Annals of Thoracic Surgery (1992), 54(5), 983-4

We report the case of a 57-year-old female cardiac transplant patient in whom an aneurysm of the recipient side of the ascending aorta developed 1 year after transplantation. Although a mycotic origin was ... [more ▼]

We report the case of a 57-year-old female cardiac transplant patient in whom an aneurysm of the recipient side of the ascending aorta developed 1 year after transplantation. Although a mycotic origin was the likely cause, histologic examination diagnosed an atherosclerotic aneurysm. [less ▲]

Detailed reference viewed: 41 (0 ULg)
See detailDigital Mapping and GIS in Belgium
Donnay, Jean-Paul ULg; Sanders, Jan

in Mapping Awareness (1992), 6(2), 19-26

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailPhotoionization Mass Spectrometry of Kinetic Energy-selected ions. The Translational Energy Distribution of N+/N2 in the Inner-shell Ionization energy range.
Locht, Robert ULg; Denzer, W.; Rühl, E. et al

in Chemical Physics (1992), 160

An ion retarding potential difference (IRPD) method has been used to investigate the ion yield and the kinetic energy distributions of N+/N2 produced by photoionization mass spectrometry using synchrotron ... [more ▼]

An ion retarding potential difference (IRPD) method has been used to investigate the ion yield and the kinetic energy distributions of N+/N2 produced by photoionization mass spectrometry using synchrotron radiation. Photoion yield curves of energy selected N+ ions are deduced. Translational energy distributions of N+ at the energies of the N(1s)->pi*, N(1s)->(nl)1 and above the N(1s)-1 threshold are determined. Comparison is made with previous photoion-photoelectron coincidence work using time-of-flight (TOF) measurements. [less ▲]

Detailed reference viewed: 34 (0 ULg)
Full Text
Peer Reviewed
See detailApplications de l'échographie en reproduction bovine. 1. L'examen des ovaires.
Hanzen, Christian ULg; Laurent, Yves; Jakovljevic, Samy

in Annales de Médecine Vétérinaire (1992), 137

Detailed reference viewed: 203 (4 ULg)
Peer Reviewed
See detailInheritance and wealth composition
Pestieau, Pierre ULg; Perelman, Sergio ULg

in Journal of Population Economics (1992), (5), 305-318

This paper studies the effects of variables pertaining to alternative bequest motives on the composition of households' portofolio. It relies on a 1986 survey on the assets structure of 5600 French ... [more ▼]

This paper studies the effects of variables pertaining to alternative bequest motives on the composition of households' portofolio. It relies on a 1986 survey on the assets structure of 5600 French households. The main conclusion is that bequest motives indeed influence the composition of households' wealth. However, available data does not allow one to sort out the influence of specific models of inheritance. [less ▲]

Detailed reference viewed: 8 (2 ULg)
See detailDistribution spatiale et préférences écologiques chez les Diplopodes du sol
Kime, R. D.; Dufrêne, Marc ULg; Wauthy, G. et al

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), 35

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailSeduzione e malattia nella narrativa italiana postunitaria
Curreri, Luciano ULg

in Otto/Novecento (1992), (3/4), 53-78

Detailed reference viewed: 50 (9 ULg)
Peer Reviewed
See detailDISTINGUISHEDNESS OF WEIGHTED FRECHET SPACES OF CONTINUOUS-FUNCTIONS
Bastin, Françoise ULg

in Proceedings Of The Edinburgh Mathematical Society (1992), 35(Part 2), 271-283

In this paper, we prove that if U is an increasing sequence of strictly positive and continuous functions on a locally compact Hausdorff space X such that VBAR congruent-to VBAR and C(X), then the Frechet ... [more ▼]

In this paper, we prove that if U is an increasing sequence of strictly positive and continuous functions on a locally compact Hausdorff space X such that VBAR congruent-to VBAR and C(X), then the Frechet space CU(X) is distinguished if and only if it satisfies Heinrich's density condition, or equivalently, if and only if the sequence U satisfies condition (H) (cf. e.g.`[1] for the introduction of (H)). As a consequence, the bidual lambda(infinity)(A) of the distinguished Kothe echelon space lambda-0(A) is distinguished if and only if the space lambda-1(A) is distinguished. This gives counterexamples to a problem of Grothendieck in the context of Kothe echelon spaces. [less ▲]

Detailed reference viewed: 17 (0 ULg)
Full Text
Peer Reviewed
See detailLe role du PAF et de ses antagonistes dans l'asthme bronchique.
MASSION, Paul ULg; Frans, A.

in Revue de Pneumologie Clinique (1992), 48(2), 49-57

Inhalation of the platelet activating factor (PAF) produces symptoms of bronchial asthma, a disease in which PAF plays an important role. This lipid mediator released by many kinds of cells exerts its ... [more ▼]

Inhalation of the platelet activating factor (PAF) produces symptoms of bronchial asthma, a disease in which PAF plays an important role. This lipid mediator released by many kinds of cells exerts its effects on blood cells and on cells of the bronchial wall both directly and indirectly. The crucial role played by PAF in the inflammatory cascades explains the current interest in specific PAF antagonists. These antagonists have both bronchodilator and anti-inflammatory properties and act simultaneously as beta-adrenoceptor agonists and corticosteroids. The first clinical trials of PAF antagonists in the treatment of resistant asthma have given results that are interesting but not superior to those obtained with the conventional anti-asthmatic drugs. The indications for PAF antagonists combined with other specific antagonists will soon be determined. [less ▲]

Detailed reference viewed: 24 (1 ULg)
Full Text
Peer Reviewed
See detailDétermination en mode maillé du champ d’intervisibilité dans un modèle numérique de terrain
Donnay, Jean-Paul ULg

in Cartographica (1992), 29(Autumn/Winter), 75-82

Detailed reference viewed: 11 (1 ULg)
Peer Reviewed
See detailRelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.
Ryseck, R. P.; Bull, P.; Takamiya, M. et al

in Molecular & Cellular Biology (1992), 12(2), 674-84

We have identified a serum-inducible gene, relB, which encodes a protein of 558 amino acids containing a region with high similarity to c-Rel and other members of the Rel family. Transcriptional ... [more ▼]

We have identified a serum-inducible gene, relB, which encodes a protein of 558 amino acids containing a region with high similarity to c-Rel and other members of the Rel family. Transcriptional activation analysis of GAL4-RelB fusion proteins in yeast cells reveals that RelB contains in its C-terminal 180 amino acids a transcriptional activation domain. The N-terminal part including the region of similarity with the Rel family shows no detectable transcriptional activity. RelB does not bind with high affinity to NF-kappa B sites, but heterodimers between RelB and p50-NF-kappa B do bind to different NF-kappa B-binding sites with a similar affinity to that shown by p50-NF-kappa B homodimers. However, RelB/p50-NF-kappa B heterodimers, in contrast to p50-NF-kappa B homodimers, transactivate transcription of a promoter containing a kappa B-binding site. [less ▲]

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailUSE OF SEDIMENTARY CLAY-MINERALS FOR THE RECONSTITUTION OF PERIODIC PALEOCLIMATIC VARIATIONS IN THE ARABIAN SEA
Fagel, Nathalie ULg; Debrabant, Pierre; DE Menocal, Peter et al

in Oceanologica Acta (1992), 15(2), 125-136

During the Late Neogene, the sediments of the Owen ridge (Arabian Sea) were able to record paleoclimatic variations because of tectonic stability and weak bio-turbation. These changes had a powerful ... [more ▼]

During the Late Neogene, the sediments of the Owen ridge (Arabian Sea) were able to record paleoclimatic variations because of tectonic stability and weak bio-turbation. These changes had a powerful influence on the western, northern and northeastern detrital supplies related to monsoon conditions and low-latitude aridity which developed during glaciary stages. In ODP Leg 117 sites, previous studies on the distribution of clay assemblages show a great variety of mineral origins and their fluctuating contribution to the Neogene sedimentation. Concurrent investigations of the sedimentological, magnetic, biogenic and geochemical properties of sediments have emphasized typical periodic sedimentary responses related to external forced functions of the earth's orbital parameters. This research investigates whether the clay fraction is able to record short-term periodicities. For this purpose we sampled site 721 with high-resolution over a short Plio-Pleistocene interval well known from magnetic susceptibility measurements. We chose the palygorskite/illite peak ratio, directly measured on the XR diffractograms, as a typical clay parameter. The fluctuations of this parameter, between 2.7 and 1.2 My, defined a time-series which has been treated by spectral analysis: autocorrelation, discrete Fourier Transform (DFI) and DFT of the autocorrelation function (DFTA). The results on the global signal (1.5 My) and on four fractions of 375 Ky, are analysed and discussed. On the spectrograms some peaks are close to the classical Milankovitch cycles of the earth's orbital parameters, but additional periods occur with high amplitude. They represent non-linear responses of the eccentricity and of the tilting cyclicities. The periodic influences change with time from a signal dominated by the precession to a signal dominated by the tilting. This shift appears at 2.4 My and reflects the transition from a dominant regional effect (monsoon) to a global and more complex effect (extension of the ice sheets). These results, which show the clay fraction to be an accurate marker of short-term paleoclimate variations, confirm some previous knowledge obtained with magnetic susceptibility data and indicate in greater detail the mode of detrital supply of the Northwest Indian Ocean. Prior to 2.4 My, the palygorskite-illite ratio data vary predominantly at the precessionnal periodicities and record the modulation of the southwest monsoon intensity and associated northwest winds. After 2.4 My the acidification of North-East Africa and Arabia (monsoonal dust areas), with expanded high-latitude ice cover, favours fibrous clay formation in well-developed pericontinental evaporitic basins. Like the illite flux, the palygorskite flux is modulated by a non-linear continental response that varied in response to the orbital obliquity periodicity. [less ▲]

Detailed reference viewed: 57 (13 ULg)
Peer Reviewed
See detailMacromixing versus hydrodynamics in trickle-flow columns
Crine, Michel ULg; Marchot, Pierre ULg; Lekhlif, B. et al

in Chemical Engineering Science (1992), 47

Detailed reference viewed: 6 (1 ULg)
Peer Reviewed
See detailLocalization of the human KRAB finger gene ZNF117 (HPF9) to chromosome 7q11.2
Bellefroid, Eric J.; Ried, Thomas; Riviere, Michele et al

in Genomics (1992), 14(3), 780-1

A cluster of Kruppel type zinc finger genes of the KRAB subclass has recently been localized on human chromosome 19p12-p13.1. We now report that ZNF117 (HPF9), a closely related zinc finger gene of this ... [more ▼]

A cluster of Kruppel type zinc finger genes of the KRAB subclass has recently been localized on human chromosome 19p12-p13.1. We now report that ZNF117 (HPF9), a closely related zinc finger gene of this KRAB subfamily, has been assigned to a distinct locus in the human genome: chromosome band 7q11.2. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Peer Reviewed
See detailRegulation endocrinienne et manipulation de la croissance bovine
Renaville, Robert ULg; Sneyers, M.; Devolder, A. et al

in Cahiers Agricultures (1992), 1(2),

Detailed reference viewed: 8 (4 ULg)
Full Text
Peer Reviewed
See detailPreparation of poly(D,L)lactide microspheres by emulsion-solvent evaporation and their clinical applications as a convenient embolic material
Grandfils, Christian ULg; Flandroy, P; Nihant, N et al

in Journal of Biomedical Materials Research (1992), 26

Detailed reference viewed: 6 (0 ULg)