References of "Article"
     in
Bookmark and Share    
Peer Reviewed
See detailL'intensité des soins en gériatrie : élaboration d'un document de réflexion
Petermans, Jean ULg

in Revue Médicale de Bruxelles (2002), 23

Detailed reference viewed: 96 (8 ULg)
Full Text
Peer Reviewed
See detailPharma clinics. Comment je traite ... un herpes labial récurrent.
Petit, L.; Braham, C.; Nikkels, Arjen ULg et al

in Revue Médicale de Liège (2002), 57(2), 67-71

Recurrent herpes labialis is a frequent disorder. It occurs following the reactivation of the Herpesvirus (HSV1 and more rarely HSV2) inside the Gasser ganglion. Treatment and prevention of recurrent ... [more ▼]

Recurrent herpes labialis is a frequent disorder. It occurs following the reactivation of the Herpesvirus (HSV1 and more rarely HSV2) inside the Gasser ganglion. Treatment and prevention of recurrent labial herpes are targeted by specific antiviral agents. Spectacular benefits obtained in the immunocompromised patients are less convincing in otherwise healthy subjects. Other prospective ways of therapy are under consideration, including lipopeptides and physical means aiming at modifying the cutaneous pH. [less ▲]

Detailed reference viewed: 297 (4 ULg)
Full Text
Peer Reviewed
See detailAspects de la conclusion du contrat par voie électronique
Biquet, Christine ULg; Decharneux, Joëlle ULg

in Actualités du Droit (2002)

Detailed reference viewed: 73 (15 ULg)
Full Text
Peer Reviewed
See detailLes sobriquets de Pompée dans la correspondance de Cicéron
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (2002), 61(1, JAN-MAR), 41-45

Detailed reference viewed: 50 (1 ULg)
Full Text
Peer Reviewed
See detailUse of specific bioluminescent cell lines for the detection of steroid hormone (ant)agonists in meat producing animals
Willemsen, Philippe; Scippo, Marie-Louise ULg; Maghuin-Rogister, Guy ULg et al

in Analytica Chimica Acta (2002), 473(1-2), 119-126

We present stable transformed human mammary cell lines displaying highly inducible steroid receptor-mediated luciferase reporter gene expression. The utilization of a cell-based assay for detection of ... [more ▼]

We present stable transformed human mammary cell lines displaying highly inducible steroid receptor-mediated luciferase reporter gene expression. The utilization of a cell-based assay for detection of steroid agonists and antagonists down to 0.3 ng g(-1) is described and its application to the analysis of bovine samples is discussed. In particular, the use of the assays to detect illegal progesterone or androgen treatment has to take into account the presence of natural endogenous hormones. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

Detailed reference viewed: 49 (3 ULg)
Full Text
Peer Reviewed
See detailCross Border Health Care : an Analysis of Recent ECJ Rulings
Fecher-Bourgeois, Fabienne ULg; Paulus, Aggie; Evers, Sylvia et al

in European Journal of Law and Economics (2002), 14

Detailed reference viewed: 37 (10 ULg)
Full Text
See detailRestorative Justice: Activities and expectations at European LEvel
Lauwaert, Katrien ULg; Aertsen, Ivo

in Era Forum : Scripta Iuris Europaei (2002)

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailLa Vierge comme protectrice des Pays-Bas méridionaux dans les livrets de pèlerinage marial au XVIIe siècle
Delfosse, Annick ULg

in Revue Belge de Philologie et d'Histoire (2002), 80(4), 1225-1241

Study of the dual symbolic function assigned by the Belgian pilgrimage booklets to the Virgin Mary in the 17th Century: the miraculous Madonnas worshiped in the shrines to cure the private individual’s ... [more ▼]

Study of the dual symbolic function assigned by the Belgian pilgrimage booklets to the Virgin Mary in the 17th Century: the miraculous Madonnas worshiped in the shrines to cure the private individual’s troubles are indeed also invoked to dress the wounds of a nation mangled and manhandled by the civic wars. [less ▲]

Detailed reference viewed: 169 (15 ULg)
Full Text
Peer Reviewed
See detailIdentification of bioindicator species among Ephemeroptera, Plecoptera and Trichoptera in a survey of streams belonging to the rhithral classification in the Grand Duchy of Luxembourg
Dohet, A.; Dolisy, D.; Hoffmann, L. et al

in Verhandlungen der Internationalen Vereinigung für Theoretische und Angewandte Limnologie = Proceedings of the International Association of Theoretical and Applied Limnology (2002), 28

Detailed reference viewed: 63 (8 ULg)
Full Text
Peer Reviewed
See detailPrenons garde aux lésions kystiques cutanées. Du dérisoire au méritoire.
Hermanns-Lê, Trinh ULg; Hermanns, Jean-François ULg; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2002), 57(5), 314-6

Cutaneous cystic-like lesions do not always correspond to real epithelial cysts. Indeed, the histological examination may identify another benign tumour. But, in some instances, the surprise may be ... [more ▼]

Cutaneous cystic-like lesions do not always correspond to real epithelial cysts. Indeed, the histological examination may identify another benign tumour. But, in some instances, the surprise may be greater. We report three patients in whom lesions suggested clinically small cysts. However, they were malignant neoplasms corresponding to a malignant fibrous histiocytoma, an epithelioid angiosarcoma and a metastatic adenocarcinoma, respectively. [less ▲]

Detailed reference viewed: 39 (6 ULg)
Full Text
Peer Reviewed
See detailDirect effect of ice sheets on terrestrial bicarbonate, sulphate and base cation fluxes during the last glacial cycle: minimal impact on atmospheric CO2 concentrations
Tranter, Martyn; Huybrechts, Philippe; Munhoven, Guy ULg et al

in Chemical Geology (2002), 190(1-4), 33-44

Chemical erosion in glacial environments is normally a consequence of chemical weathering reactions dominated by sulphide oxidation linked to carbonate dissolution and the carbonation of carbonates and ... [more ▼]

Chemical erosion in glacial environments is normally a consequence of chemical weathering reactions dominated by sulphide oxidation linked to carbonate dissolution and the carbonation of carbonates and silicates. Solute fluxes from small valley glaciers are usually a linear function of discharge. Representative glacial solute concentrations can be derived from the linear association of solute flux with discharge. These representative glacial concentrations of the major ions are similar to 25% of those in global river water. A 3-D thermomechanically coupled model of the growth and decay of the Northern Hemisphere ice sheets was used to simulate glacial runoff at 100-year time steps during the last glacial cycle (130 ka to the present). The glacially derived fluxes of major cations, anions and Si over the glaciation were estimated from the product of the glacial runoff and the representative glacial concentration. A second estimate was obtained from the product of the glacial runoff and a realistic upper limit for glacial solute concentrations derived from theoretical considerations. The fluxes over the last glacial cycle are usually less than a few percent of current riverine solute fluxes to the oceans. The glacial fluxes were used to provide input to an oceanic carbon cycling model that also calculates changes in atmospheric CO2. The potential change in atmospheric CO2 concentrations over the last glacial cycle that arise from perturbations in glacial solute fluxes are insignificant, being < 1 ppm. [less ▲]

Detailed reference viewed: 16 (2 ULg)
Full Text
Peer Reviewed
See detailStreamlining cosmetology by standardized testing?
Pierard, Gérald ULg

in Journal of Cosmetic Dermatology (2002), 1(2), 97-898

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailBelgian peer review experience on the Achille's heel in haemodialysis care: vascular access
Theelen, Bernadette ULg; Rorive, Georges ULg; Krzesinski, Jean-Marie ULg et al

in EDTNA/ERCA Journal (2002), 28(4, Oct-Dec), 164-166

AIMS: In order to improve the supervision and to evaluate the quality of care in dialysis units, a national project was promoted as a Peer Review. It consisted of systematic, continuous and critical ... [more ▼]

AIMS: In order to improve the supervision and to evaluate the quality of care in dialysis units, a national project was promoted as a Peer Review. It consisted of systematic, continuous and critical evaluation of the care and the application of international guidelines and compared the reality of care with standards. METHOD: The first chart consisted of the evaluation of infectious episodes of vascular access. This point is particularly relevant since infection represents the second cause of mortality in haemodialysis. A questionnaire concerning each patient was designed. Questions concerned the description of vascular access and the related infectious events. Each questionnaire included 21 items. The project involved 29 dialysis centres, 1,644 patients and 1,775 vascular accesses. The database included 90,525 data. RESULTS: Among the 29 centres, the native arteriovenous fistula (AVF) is the first choice (67.5%) in vascular access, but the proportion of AVF decreases with age contrary to the catheter, which is more frequently chosen, in older patients. Independent of age, 20% of hospitalisations are among patients with catheters and only 7% among patients with AVF. The RR (relative risk) of being hospitalised (any complication of vascular access) is 1.68 for patients with catheters compared to patients with AVF. The rate of infections does not increase with age but is higher for patients with catheters (RR = 2.26). The number of infections appears to be dependent on the staphylococcus aureus carriage in the year. CONCLUSIONS: This first step allows each centre to compare itself to others in an anonymous way. This approach should lead to specific recommendations to improve the quality of care in dialysis units. [less ▲]

Detailed reference viewed: 29 (1 ULg)
Full Text
Peer Reviewed
See detailRapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.
Limbourg, Florian P; Huang, Zhihong; Plumier, Jean-Christophe ULg et al

in Journal of Clinical Investigation (2002), 110(11), 1729-38

Many cellular responses to corticosteroids involve the transcriptional modulation of target genes by the glucocorticoid receptor (GR). A rapid, non-nuclear effect of GR was found to mediate ... [more ▼]

Many cellular responses to corticosteroids involve the transcriptional modulation of target genes by the glucocorticoid receptor (GR). A rapid, non-nuclear effect of GR was found to mediate neuroprotection. High-dose corticosteroids (20 mg/kg intraperitoneally), given within 2 hours of transient cerebral ischemia, acutely increased endothelial nitric oxide synthase (eNOS) activity, augmented regional cerebral blood flow (CBF) by 40% to 50%, and reduced cerebral infarct size by 32%. These neuroprotective effects of corticosteroids were abolished by the GR antagonist RU486 and by inhibition of phosphatidylinositol 3-kinase (PI3K), and were absent in eNOS(-/-) mice. To determine the mechanism by which GR activated eNOS, we measured the effect of corticosteroids on PI3K and the protein kinase Akt. In a ligand-dependent manner, GR activated PI3K and Akt in vitro and in vivo caused NO-dependent vasodilation, which was blocked by cotreatment with RU486 or the PI3K inhibitor LY294002 but not by transcriptional inhibitors. Indeed, a mutant GR, which cannot dimerize and bind to DNA, still activated PI3K and Akt in response to corticosteroids. These findings indicate that non-nuclear GR rapidly activates eNOS through the PI3K/Akt pathway and suggest that this mechanism mediates the acute neuroprotective effects of corticosteroids through augmentation of CBF. [less ▲]

Detailed reference viewed: 55 (3 ULg)
Full Text
Peer Reviewed
See detailAbsolute and relative contraindications to liver transplantation. A perpetually moving frontier.
Detry, Olivier ULg; De Roover, Arnaud ULg; Delwaide, Jean ULg et al

in Acta Gastro-Enterologica Belgica (2002), 65(2), 133-4

In this paper the authors discussed the absolute and relative contraindications to liver transplantation. These contraindications are not fixed, and may change with medical progress and experience ... [more ▼]

In this paper the authors discussed the absolute and relative contraindications to liver transplantation. These contraindications are not fixed, and may change with medical progress and experience. Certainly, the recent advent of adult-to-adult living related liver transplantation may somehow change the management of patients with relative contra-indications to cadaveric liver transplantation, as they may be potential candidates for living related liver transplantation. [less ▲]

Detailed reference viewed: 85 (24 ULg)
Full Text
See detailImplications pour la communauté d'un meilleur contrôle de la pression artérielle
Krzesinski, Jean-Marie ULg

in Journal de Cardiologie = Tijdschrift voor Cardiologie (2002), 14(5), 186-190

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailCambios en la participación política de los inmigrantes en la región de Bruselas capital. Elecciones de octubre de 2000
Martiniello, Marco ULg; Jacobs, Dirk; Rea, Andrea

in Revista Migraciones (2002), 11

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailAsymmetric dihydroxylation of C,C double bonds using catalytic amounts of osmium tetroxide, selenides, and air
Krief, A.; Colaux, Catherine ULg

in Pure & Applied Chemistry (2002), 74(1), 107-113

Selenides, selenoxides, osmium tetroxide, and potassium osmate dihydrate are in equilibrium in aqueous tert-butanol containing potassium carbonate. We took advantage of this feature to withdraw the ... [more ▼]

Selenides, selenoxides, osmium tetroxide, and potassium osmate dihydrate are in equilibrium in aqueous tert-butanol containing potassium carbonate. We took advantage of this feature to withdraw the equilibrium in each of the two directions to produce allylalcohols from allylselenides and diols from olefins. The latter reaction performed in the presence of catalytic amounts of Cinchona alkaloids and osmium tetroxide allows the enantioselective dihydroxylation of C,C double bonds. [less ▲]

Detailed reference viewed: 23 (2 ULg)
Full Text
Peer Reviewed
See detailEvolution pluviométrique et relation inondations – événements pluvieux au Sénégal
Sene, Souleymane; Ozer, Pierre ULg

in Bulletin de la Société Géographique de Liège (2002), 42

Since the late 1960s, Senegal suffered from the dramatic drought which affected all the Sahel of West Africa. Thirty years later, rainfall amounts well above the 1961-1990 average may announce the end of ... [more ▼]

Since the late 1960s, Senegal suffered from the dramatic drought which affected all the Sahel of West Africa. Thirty years later, rainfall amounts well above the 1961-1990 average may announce the end of this period of aridity. Together with this rainfall increase, floods have been reported in most Senegalese cities in 1999, 2000 and 2001. Because of these floods, many affected areas have been abandoned and stricken population has to be rehoused in precarious conditions. Most analysts consider these floods as a new phenomenon, never observed before, and they are blamed on the exceptional heavy daily rainfall. Analysing the relationship between floods and rainfall events in 1999 et 2000, it appears that rainfall amounts responsible for the beginning of each flood are far to be exceptional. However, the vulnerability of the Senegalese cities facing the risk of flood seems to have increased as a result of urban mismanagement. [less ▲]

Detailed reference viewed: 831 (35 ULg)
Full Text
Peer Reviewed
See detailInfo-congres. Essai de prevention du diabete de type 1 par le nicotinamide: les lecons positives d'un essai clinique negatif (ENDIT).
Philips, Jean-Christophe ULg; Scheen, André ULg

in Revue Médicale de Liège (2002), 57(10), 672-5

ENDIT ("European Nicotinamide Diabetes Intervention Trial") is a large placebo-controlled randomised clinical trial that aimed at studying the efficacy of nicotinamide in the prevention of type 1 diabetes ... [more ▼]

ENDIT ("European Nicotinamide Diabetes Intervention Trial") is a large placebo-controlled randomised clinical trial that aimed at studying the efficacy of nicotinamide in the prevention of type 1 diabetes mellitus among first-degree relatives of type 1 diabetic patients with positive islet cell antibodies (ICA). The results presented at the last congress of the European Association for the Study of Diabetes (EASD) in Budapest do not evidence any significant difference in the risk of developing overt diabetes mellitus in the patients treated with nicotinamide (n = 274) as compared to those receiving placebo (n = 275) after 5 years of follow-up. Despite these negative results, positive lessons could be drawn from ENDIT: 1) the feasibility of a large long-standing multicentre European trial in a difficult research area; 2) the importance of large randomised controlled clinical trials to bring the evidence requested by "Evidence-Based Medicine"; 3) the predictive value of various risk markers to progress toward type 1 diabetes in first-degree relatives, especially the number of positive auto-antibodies; and 4) the urgent need to continue intensive research in this important field of preventive medicine. [less ▲]

Detailed reference viewed: 246 (1 ULg)
Full Text
Peer Reviewed
See detailComparison of plasma cardiac troponins T and I in chronically hemodialyzed patients in relation to cardiac status and age
Chapelle, Jean-Paul ULg; Dubois, Bernard ULg; Bovy, Christophe ULg et al

in Clinical Chemistry & Laboratory Medicine (2002), 40(3), 240-245

Detailed reference viewed: 22 (0 ULg)
Full Text
Peer Reviewed
See detailUse of multisite quantitative ultrasonography for noninvasive assessment of bone in horses
Carstanjen, B.; Lepage, O. M.; Detilleux, Johann ULg et al

in American Journal of Veterinary Research (2002), 63(10), 1464-1469

OBJECTIVE: To evaluate the usefulness of multisite quantitative ultrasonography for noninvasive assessment of bone in horses. SAMPLE POPULATION: 12 healthy horses and both forelimbs from 8 clinically ... [more ▼]

OBJECTIVE: To evaluate the usefulness of multisite quantitative ultrasonography for noninvasive assessment of bone in horses. SAMPLE POPULATION: 12 healthy horses and both forelimbs from 8 clinically normal horses. PROCEDURE: For in vivo measurements, various regions of interest (ROI) were examined on the third metacarpal bone, radius, and tibia. Precision error for speed of sound (SOS) measurements was obtained by measuring each ROI of 4 horses 10 times with probe repositioning. Additionally, 3 operators measured each aspect of the third metacarpal bone of 6 horses 5 times each. For ex vivo measurements, third metacarpal bones were examined at 9 ROI, and SOS measurements were performed before and after soft tissue removal. One ROI of a single forelimb was subjected to 96 ex vivo measurements with 3 different contact media. RESULTS: The lateral aspect of the third metacarpal bone had significantly higher SOS values than the dorsal and medial aspect of the third metacarpal bone. No difference was obtained between SOS values of the lateral and medial aspect of the radius. The tibia had significantly higher SOS values than the lateral aspect of the radius and the dorsal and medial aspect of the third metacarpal bone. Intraoperator coefficients of variation ranged from 0.62 to 3.15%, and interoperator coefficients of variation ranged from 0.78 to 2.70%. Values of SOS were highest when silicone oil was used as the contact medium. CONCLUSIONS AND CLINICAL RELEVANCE: Speed of sound measurements obtained by quantitative ultrasonography in axial transmission mode can be used to precisely measure superficial cortical bone properties of third metacarpal bone, radius, and tibia in horses. [less ▲]

Detailed reference viewed: 15 (0 ULg)
Full Text
Peer Reviewed
See detailAg/SiO2 and Cu/SiO2 cogelled xerogel catalysts for benzene combustion and 2-butanol dehydrogenation
Lambert, Stéphanie ULg; Tcherkassova, Natalia; Cellier, Caroline et al

in Studies in Surface Science and Catalysis (2002), 143

Detailed reference viewed: 41 (15 ULg)
Full Text
Peer Reviewed
See detailC : N ratio increases in the phloem sap during floral transition of the long-day plants Sinapis alba and Arabidopsis thaliana
Corbesier, Laurent; Bernier, Georges ULg; Périlleux, Claire ULg

in Plant & Cell Physiology (2002), 43(6), 684-688

In plants of Sinapis alba and Arabidopsis thaliana, leaf exudate (phloem sap) was analysed during and after a single long day inducing flowering and in control short days. The amounts of carbohydrates and ... [more ▼]

In plants of Sinapis alba and Arabidopsis thaliana, leaf exudate (phloem sap) was analysed during and after a single long day inducing flowering and in control short days. The amounts of carbohydrates and amino acids were measured to estimate the organic C : N ratio. In both species, the C : N ratio of the phloem sap increased markedly and early during the inductive treatment, suggesting that an inequality in organic C and N supply to the apical meristem may be important at floral transition. [less ▲]

Detailed reference viewed: 62 (0 ULg)
Full Text
Peer Reviewed
See detailMedical imaging and MRI in nail disorders: report of 119 cases and review of the literature
Richert, Bertrand ULg; Baghaie, Mahmoud

in Dermatologic Therapy (2002), 15

Radiographs remain the golden standard for exploration of the bony structures located beneath the nail plate, but they provide no information on the perionychium. Until a few years ago the nail apparatus ... [more ▼]

Radiographs remain the golden standard for exploration of the bony structures located beneath the nail plate, but they provide no information on the perionychium. Until a few years ago the nail apparatus was deprived of investigative medical imaging. Glomus tumor was the only condition that was explored using invasive techniques such as angiography or scintigraphy. High-frequency ultrasound rapidly came up against technical limits. High-resolution magnetic resonance imaging (MRI) offers a superior alternative in detection of distal lesions as well as their relationship with the adjacent structures. MRI provides an accurate analysis of the nail apparatus with detection of lesions as small as 1 mm. This noninvasive technique will allow us to better understand, diagnose, and treat pathologies of the distal phalanx. [less ▲]

Detailed reference viewed: 16 (0 ULg)
Full Text
Peer Reviewed
See detailUtilisation de la ropivacaine par voie peridurale pour l'analgesie postoperatoire.
Senard, Marc ULg; Joris, Jean ULg

in Annales Françaises d'Anesthésie et de Réanimation (2002), 21(9), 713-24

OBJECTIVES: To describe pharmacology and toxicology of ropivacaine. To assess the clinical efficacy of ropivacaine when used for postoperative epidural analgesia and to provide recommendations for ... [more ▼]

OBJECTIVES: To describe pharmacology and toxicology of ropivacaine. To assess the clinical efficacy of ropivacaine when used for postoperative epidural analgesia and to provide recommendations for clinical practice. DATA SOURCES: Search in the Medline data base of original articles in French and English published since 1995, using the following key words: ropivacaine, postoperative analgesia, epidural, caudal block. STUDY SELECTION: Prospective randomised studies in adults and children were selected. Letters to editors and editorials were excluded. DATA EXTRACTION: Articles have been analyzed: to determine the dose of ropivacaine required for postoperative epidural analgesia, to assess the benefits of combination of epidural ropivacaine and additives (opioids or other), to compare epidural ropivacaine and bupivacaine and to assess the use of ropivacaine via caudal route for paediatric postoperative analgesia. DATA SYNTHESIS: 20 mg h-1 of ropivacaine is required to provide effective analgesia. This dose produces a motor block in a significant number of patients. Combination with an opioid allows for a reduction in ropivacaine requirement and subsequently in the incidence of motor blockade. In adults, equipotency ratio of ropivacaine and bupivacaine varies between 1.5/1 and 1/1 depending upon the concentration used. At equipotent doses, early postoperative mobilisation is facilitated with ropivacaine. In case of paediatric caudal analgesia, this ratio is close to 1. CONCLUSIONS: Epidural ropivacaine combined with opioid provide good postoperative pain relief. Reduction in the incidence of motor blockade and safe toxicological profile make this local anaesthetic a suitable alternative of bupivacaine for postoperative epidural analgesia. [less ▲]

Detailed reference viewed: 86 (1 ULg)
Full Text
See detailLe vol du cheval sacré
Swennen, Philippe ULg

in Acta Orientalia Belgica (2002), XVI

Detailed reference viewed: 40 (2 ULg)
Full Text
Peer Reviewed
See detailRetrosynthetic analysis of fullerene C-60: structure, stereochemistry and calculated stability of C-30 fragments
Geneste, Florence; Moradpour, Alec; Dive, Georges ULg et al

in Journal of Organic Chemistry (2002), 67(2), 605-607

Detailed reference viewed: 20 (1 ULg)
Full Text
Peer Reviewed
See detailUn moine est mort : sa vie commence.Anno 1048 obiit Poppo abbas Stabulensis.
George, Philippe ULg

in Moyen Age (Le) (2002), 108(3-4), 497-506

Poppo, the abbot at Stavelot-Malmedy died in the abbey of Marchiennes in Hainaut on 25 January 1048. The scene of the saint's death, which his hagiographer described in grand manner some ten years later ... [more ▼]

Poppo, the abbot at Stavelot-Malmedy died in the abbey of Marchiennes in Hainaut on 25 January 1048. The scene of the saint's death, which his hagiographer described in grand manner some ten years later, deserves to be examined closely, as indeed the staging of his funeral, this stepping onto the threshold of "rebirth" into eternal life and sainthood (dies natalis). The Vita Popponis follows the rules of the hagiographic genre, in which the monk's death is inevitably highlighted. [less ▲]

Detailed reference viewed: 24 (1 ULg)
Full Text
Peer Reviewed
See detailRadiologic features poorly predict clinical outcomes in knee osteoarthritis.
Bruyère, Olivier ULg; Honore, Aline; Rovati, Lucio C et al

in Scandinavian Journal of Rheumatology (2002), 31(1), 13-6

OBJECTIVES: To assess the impact of radiographic severity and progression on pain and disability. METHODS: Measurements of mean joint space width (JSW), narrowest join space (NJS) point and assessment of ... [more ▼]

OBJECTIVES: To assess the impact of radiographic severity and progression on pain and disability. METHODS: Measurements of mean joint space width (JSW), narrowest join space (NJS) point and assessment of symptoms by the WOMAC questionnaire were performed at baseline and after three years in 212 subjects over 50 years with primary knee OA. RESULTS: At baseline, JSW and NJS were not significantly correlated with the scores recorded for the WOMAC global index or its pain, stiffness or function subscales. A statistically significant correlation was observed between the joint space narrowing over three years and the changes observed in the pain subscale of the WOMAC during the same period. The three-year changes in the global WOMAC index in patients within the lowest and the highest quartiles of mean joint space width at baseline showed, in both cases, a statistically (p<0.05) significant favorable difference between patients treated with glucosamine sulphate and those having received placebo. CONCLUSION: Radiographic and clinical progressions of the disease are significantly associated but the clinical relevance of the association is questionable. [less ▲]

Detailed reference viewed: 42 (8 ULg)
Full Text
Peer Reviewed
See detailQuelques Névroptères d’un site de la région liégeoise (ru de Targnon, Theux, Belgique)
Mignon, Jacques ULg

in Notes Fauniques de Gembloux (2002), 47

Detailed reference viewed: 20 (6 ULg)
Full Text
Peer Reviewed
See detailLa précession du plan d'oscillation du pendule de Foucault : une approche géométrique intuitive
De Rop, Yves ULg; Moreau, Olivier

in Revue des Questions Scientifiques (2002), 173(3), 261-276

Detailed reference viewed: 40 (5 ULg)
Full Text
See detailEtalonnage de l’épreuve grapho-perceptive de Bender sur une population d’enfants de six à dix ans
Garcet, Serge ULg; Deltour, Jean-Jacques

in Revue Scientifique de l'AIGS (2002), 1

Detailed reference viewed: 1570 (2 ULg)
Full Text
Peer Reviewed
See detailThe Disulphide Mapping, Folding and Characterisation of Recombinant Ber e 1, an Allergenic Protein, and SFA8, Two Sulphur-rich 2 S Plant Albumins
Alcocer, Marcos; Murtagh, G. J.; Bailey, Kevin et al

in Journal of Molecular Biology (2002), 324

We have cloned and expressed genes encoding the allergenic brazil nut 2 S albumin (Ber e 1) and the sunflower albumin 8 (SFA8) in the methylotrophic yeast Pichia pastoris. We show that both proteins were ... [more ▼]

We have cloned and expressed genes encoding the allergenic brazil nut 2 S albumin (Ber e 1) and the sunflower albumin 8 (SFA8) in the methylotrophic yeast Pichia pastoris. We show that both proteins were secreted at high levels and that the purified proteins were properly folded. We also showed that Ber e 1 is glycosylated during secretion and that the glycan does not interfere with the folding or immunoreactivity. The disulphide map of the Ber e 1 protein was experimentally established and is in agreement with the conserved disulphide structure of other members of the 2 S albumin family. A model three-dimensional structure of the allergen was generated. During the expression studies and through mutation we have also shown that alteration of the sequences around the Kex2 endoproteolytic processing site in the expressed fusion protein can compromise the secretion by targeting part of the protein for possible degradation. The secreted production of these properly folded sulphurrich plant albumins presents an opportunity to delineate the attributes that make an allergen and to facilitate the diagnosis and therapy of type I allergy. [less ▲]

Detailed reference viewed: 31 (2 ULg)
Full Text
Peer Reviewed
See detailTabagisme, insulinoresistance et diabete de type 2.
Magis, Delphine ULg; Geronooz, I.; Scheen, André ULg

in Revue Médicale de Liège (2002), 57(9), 575-81

Smoking is a major risk factor for cardiovascular disease. It is associated with endothelial dysfunction and lipid disorders similar to those found in the insulin resistance syndrome. Studies have thus ... [more ▼]

Smoking is a major risk factor for cardiovascular disease. It is associated with endothelial dysfunction and lipid disorders similar to those found in the insulin resistance syndrome. Studies have thus tried to demonstrate a relationship between smoking and insulin resistance, and between smoking and type 2 diabetes mellitus. Even if their results may sometimes differ, smoking does seem to be associated with an impaired insulin sensitivity that is proportional to tobacco consumption. Nicotine replacement therapies seem also to generate a certain, though lower, degree of insulin resistance. If there is no major weight gain after smoking cessation, the latter is accompanied by a progressive return to normal insulin sensitivity. Several large epidemiological studies recently demonstrated that smoking could increase the risk of type 2 diabetes mellitus, with a relative risk between 1.5 and 3.0. Finally, among type 2 diabetic patients, smoking has a harmful effect on metabolic control and long-term complications of the disease, at least partially by increasing the components of the insulin resistance syndrome. All these observations represent further argument to promote smoking cessation in the general population, and more particularly in individuals at risk to develop type 2 diabetes, as well as in the diabetic population. [less ▲]

Detailed reference viewed: 243 (11 ULg)
Full Text
Peer Reviewed
See detailComparant mais pas fondateur
Caprasse, Olivier ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2002)

Detailed reference viewed: 47 (3 ULg)
Full Text
Peer Reviewed
See detailClassical and Bayesian inference in neuroimaging: Applications
Friston, Karl J; Glaser, Daniel E; Henson, Richard NA et al

in Neuroimage (2002), 16(2), 484-512

In Friston et al. ((2002) Neuroimage 16: 465-483) we introduced empirical Bayes as a potentially useful way to estimate and make inferences about effects in hierarchical models. In this paper we present a ... [more ▼]

In Friston et al. ((2002) Neuroimage 16: 465-483) we introduced empirical Bayes as a potentially useful way to estimate and make inferences about effects in hierarchical models. In this paper we present a series of models that exemplify the diversity of problems that can be addressed within this framework. In hierarchical linear observation models, both classical and empirical Bayesian approaches can be framed in terms of covariance component estimation (e.g., variance partitioning). To illustrate the use of the expectation-maximization (EM) algorithm in covariance component estimation we focus first on two important problems in fMRI: nonsphericity induced by (i) serial or temporal correlations among errors and (ii) variance components caused by the hierarchical nature of multisubject studies. In hierarchical observation models, variance components at higher levels can be used as constraints on the parameter estimates of lower levels. This enables the use of parametric empirical Bayesian (PEB) estimators, as distinct from classical maximum likelihood (ML) estimates. We develop this distinction to address: (i) The difference between response estimates based on ML and the conditional means from a Bayesian approach and the implications for estimates of intersubject variability. (ii) The relationship between fixed- and random-effect analyses. (iii) The specificity and sensitivity of Bayesian inference and, finally, (iv) the relative importance of the number of scans and subjects. The forgoing is concerned with within- and between-subject variability in multisubject hierarchical fMRI studies. In the second half of this paper we turn to Bayesian inference at the first (within-voxel) level, using PET data to show how priors can be derived from the (between-voxel) distribution of activations over the brain. This application uses exactly the same ideas and formalism but, in this instance, the second level is provided by observations over voxels as opposed to subjects. The ensuing posterior probability maps (PPMs) have enhanced anatomical precision and greater face validity, in relation to underlying anatomy. Furthermore, in comparison to conventional SPMs they are not confounded by the multiple comparison problem that, in a classical context, dictates high thresholds and low sensitivity. We conclude with some general comments on Bayesian approaches to image analysis and on some unresolved issues. [less ▲]

Detailed reference viewed: 34 (1 ULg)
Full Text
See detailVers une approche plus efficace du traitement de l'hypertension
Krzesinski, Jean-Marie ULg

in Cardio Spécialistes (2002), 59

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailEffets perturbateurs endocriniens des pesticides organochlorés
Charlier, Corinne ULg; Plomteux, Guy ULg

in Acta Clinica Belgica. Supplementum (2002), (1), 2-7

Xenoestrogens such organochlorine pesticides are known to induce changes in reproductive development, function or behaviour in wildlife. Because these compounds are able to modify the estrogens metabolism ... [more ▼]

Xenoestrogens such organochlorine pesticides are known to induce changes in reproductive development, function or behaviour in wildlife. Because these compounds are able to modify the estrogens metabolism, or to compete with estradiol for binding to the estrogen receptor, it may be possible that these products affect the risk of developing impaired fertility, precocious puberty or some kinds of cancer in man. Le plus ancien récit de lutte contre la pollution remonte à une légende indienne racontant que la divinité Sing-bonga était incommodée par les émanations des fours dans lesquels les Asuras fondaient leurs métaux (1). Evidemment depuis, la problématique n–a cessé de s–accroître et la contamination de la Terre par de nombreux polluants est devenue aujourd–hui un problème majeur de notre Société. La protection de notre environnement est une question capitale qui doit être respectée malgré la pression économique actuelle et qui ne cessera de croître au cours des prochaines années même si l–identification objective et indiscutable de ce qui est essentiel – donc devant être prioritairement garanti sur la planète – est difficile à cerner (2). « Un oiseau en mauvais état ne pond pas de bons oeufs » disait un proverbe grec. Mais ce n–est qu–à partir de la seconde moitié du XXème siècle que les toxicologues ont commencé à identifier les effets qu–avaient entraînés à l–échelle mondiale les pollutions émises aux XIXème siècle sur la faune sauvage et sur le cheptel (3). L–histoire contemporaine des pesticides industriels commence vers 1874 (synthèse des organochlorés) et se poursuit tout au long de ces 2 siècles en passant par la synthèse des organophosphorés (1950), des carbamates (1970) et des pyréthroïdes (1975) (4). Le dichlorodiphényltrichloroéthane (DDT) a été synthétisé pour la première fois par un étudiant en cours de préparation de sa thèse de doctorat : Othmer Zeidler. La production, reprise par les entreprises F.Mayo puis par la Geigy Co. a d–abord intéressé l–armée, puis l–agriculture. Dès la fin de la 2ème guerre mondiale, des mises en garde furent lancées à propos des effets nocifs du produit (4). Un déclin des populations de grives, d–aigles chauves, d–orfaies et de mammifères consommateurs de poissons fut constaté à partir des années 50 et dénoncé par Rachel Carson dans son célèbre appel du « Silent Spring » de 1962. Bien qu–il soit interdit en Occident depuis les années 70, ce produit a été tellement utilisé et présente une rémanence si longue qu–une contamination ubiquitaire existe aujourd–hui encore. De plus, ce produit continue à être produit aux USA pour être utilisé à des fins de démoustification dans les pays en voie de développement. Il en va de même de l–Hexachlorobenzène (HCB), un autre organochloré dont l–usage est interdit sous nos latitudes, mais reste fréquent dans d–autres pays. Ces deux exemples indiquent que le problème de la contamination continue à nous concerner, même pour des produits dont l–usage est aujourd–hui strictement réglementé ou interdit. Des effets sur la faune semblent encore actuellement devoir être attribués à ces produits. La diminution de la population des phoques dans la mer de Wadden pourrait être due à la forte contamination en composants organochlorés des poissons dont ces phoques se nourrissent (5). Exposé au DDT et à son métabolite dichlorodiphenyldichloroéthylène (DDE), le Seratherodon mossambicus présente une réduction de la sécrétion de cortisol par une action toxique cytospécifique sur l–axe hypothalamo-hypophysaire (6). Des travaux récents ont montré que le DDT et le DDE se lient chez les oiseaux et les mammifères au moyen de liaisons covalentes aux cellules de la zona fasciculata - homologue du tissu interrénal du poisson - induisant des microhémorragies. Cette « défaillance » cortisolique peut s–accompagner d–une perturbation du métabolisme glucidique et notamment d–un taux élevé de glycogène hépatique (7). Les pesticides organochlorés (DDT, DDE) entraînent également des perturbations d–ordre métabolique chez certaines espèces d–oiseaux, notamment le faucon pèlerin en Grande Bretagne et les oiseaux piscivores des grands lacs nord américains où l–on a constaté au cours des années 1960 que leur reproduction était menacée et qu–une des manifestations les plus évidentes des perturbations observées était le taux élevé de malformations (8). Des mortalités élevées de poissons ou de coquillages ont été rapportées dans des élevages situés à proximité des zones d–épandage de pesticides organophosphorés et de carbamates. En 1991, la dispersion aérienne de fenitrothion dans le but de provoquer la démoustication en Languedoc a été à l–origine de la perte de plusieurs tonnes de crevettes japonaises. L–utilisation de trichlorfon et de dichlorvos comme antiparasitaires dans des fermes d–élevages de saumons a provoqué des épisodes de mortalité importante (9). [less ▲]

Detailed reference viewed: 202 (22 ULg)
Full Text
Peer Reviewed
See detailActualités thérapeutiques des céphalées trigéminales autonomes.
Vandenheede, Michel; MAERTENS DE NOORDHOUT, Alain ULg

in Médecine et Hygiène (2002)

Detailed reference viewed: 15 (1 ULg)
Full Text
See detailRéduire la taille des classes dans l'enseignement fondamental : pour des discriminations vraiment positives...
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2002), 11-12

Detailed reference viewed: 81 (6 ULg)
Full Text
Peer Reviewed
See detailPositron emission tomography (PET) evaluation of abdominal aortic aneurysm (AAA)
SakalihasanN, Natzi ULg; Van Damme, Hendrik ULg; Gomez, P. et al

in European Journal of Vascular and Endovascular Surgery (2002), 23(5), 431-436

Background: aneurysmal disease is associated with all inflammatory Cell infiltrate and enzymatic degradation of the vessel wall. Aim of the study: to detect increased metabolic activity in abdominal ... [more ▼]

Background: aneurysmal disease is associated with all inflammatory Cell infiltrate and enzymatic degradation of the vessel wall. Aim of the study: to detect increased metabolic activity in abdominal aortic aneurysms (AAA) by means of positron emission tomography (PET-imaging). Study design: twenty-six patients with AAA underwent PET-imaging Results: in tell patients, PET-imaging revealed increased, fluoro-deoxy-glucose (18-FDG) uptake at the level of the aneurysm. Patients with positive PET-imaging had one or more of the following elements in their clinical history: history Of recent non-aortic surgery (n = 4) a painful inflammatory aortic aneurysm (n = 2). moderate low back pain (n = 2), rapid (>5 mm in 6 months) expansion (n = 4), discovery by PET-scan of a previously undiagnosed lung cancer (n = 3) or parotid tumour (n = 1). Five patients with a positive PET scan required urgent surgery within two to 30 days. Among the 16 patients with negative PET-imaging of their aneurysm, only one had recent non-aortic surgery, none of them required urgent surgery, only two had a rapidly expanding AAA, and in only one patient, PET-imaging revealed an unknown lung cancer. Conclusion: these data suggest a possible association between increased 18-FDG uptake and AAA expansion and rupture. [less ▲]

Detailed reference viewed: 86 (5 ULg)
Full Text
Peer Reviewed
See detailMR1952249, Kriegsmann, G. A. and Tilley, B. S., Microwave heating of laminate panels; J. Engrg. Math.
Rochus, Pierre ULg

in Mathematical Reviews [=MR] (2002), 44(2), 173--198

Detailed reference viewed: 17 (1 ULg)
Full Text
See detailCaractérisation de la résistance au Sénégal d'Helicoverpa armigera Hübner (Lépidoptère, Noctuidae) par bioessai et méthodes moléculaires
Moreira, Christine; Schiffers, Bruno ULg; Haubruge, Eric ULg

in Parasitica (2002), 58(2-3-4), 89-98

Un vial-test de détection de la résistance à la cyperméthrine d'Helicoverpa armigera a été vulgarisé (Programme PR-PRAO) en Afrique de l'Ouest (flacon en verre imprégné). Cette étude montre qu'à des ... [more ▼]

Un vial-test de détection de la résistance à la cyperméthrine d'Helicoverpa armigera a été vulgarisé (Programme PR-PRAO) en Afrique de l'Ouest (flacon en verre imprégné). Cette étude montre qu'à des températures de 30°C et 54°C, 4 pyréthrinoïdes et 2 organophosphorés se dégradent rapidement dans les flacons en verre. Un "kit" est présenté sous forme d'un papier filtre traité enveloppé dans une feuille d'aluminium. Il possède une bien meilleure stabilité au stockage (sur 50 jours). Des tests moléculaires, réalisés sur une souche d'H. armigera issue du Sénégal, révèlent deux mutations (la sérine remplacée par l'acide glutamique et l'acide aspartique par la valine) au niveau du gène codant pour le canal sodium voltage dépendant, cible principale des pyréthrinoïdes. [less ▲]

Detailed reference viewed: 62 (9 ULg)
Full Text
Peer Reviewed
See detailAngot salue Guibert
Demoulin, Laurent ULg

in Critique : Revue Générale des Publications Françaises et Etrangères (2002), 663-664

Le roman L'Inceste de Christine Angot s'ouvre presque sur les mêmes phrases que le roman A l'ami qui ne m'a pas sauvé la vie d'Hervé Guibert. Quelle est la valeur de ce détournement textuel et quel rôle ... [more ▼]

Le roman L'Inceste de Christine Angot s'ouvre presque sur les mêmes phrases que le roman A l'ami qui ne m'a pas sauvé la vie d'Hervé Guibert. Quelle est la valeur de ce détournement textuel et quel rôle joue-t-il dans le roman d'Angot? [less ▲]

Detailed reference viewed: 100 (8 ULg)
Full Text
See detailLe mélange épicéa-douglas, une association intéressante pour le sylviculteur ? 2e partie
Colson, Vincent ULg; Claessens, Hugues ULg; Pauwels, D. et al

in Silva Belgica (2002), 109(4), 25-31

Detailed reference viewed: 45 (10 ULg)
Full Text
Peer Reviewed
See detailCryopreservation For The Elimination Of Cucumber Mosaic And Banana Streak Viruses From Banana (Musa Spp.)
Helliot, Bertrand; Panis, B.; Poumay, Y. et al

in Plant Cell Reports (2002), 20(12), 1117-1122

Detailed reference viewed: 45 (3 ULg)
Full Text
Peer Reviewed
See detailStudy of the structural, electronic, and magnetic properties of the barium-rich iron(IV) oxides, Ba2FeO4 and Ba3FeO5
Delattre, J. L.; Stacy, A. M.; Young, V. G. et al

in Inorganic Chemistry (2002), 41(11), 2834-2838

Crystals of Ba2FeO4 and Ba3FeO5, grown from a "self-sealing" KOH-Ba(OH)(2) flux, have been characterized by single-crystal X-ray diffraction, Mossbauer spectroscopy, and magnetic measurements. Ba2FeO4 ... [more ▼]

Crystals of Ba2FeO4 and Ba3FeO5, grown from a "self-sealing" KOH-Ba(OH)(2) flux, have been characterized by single-crystal X-ray diffraction, Mossbauer spectroscopy, and magnetic measurements. Ba2FeO4 forms nonmerohedral twinned crystals with the monoclinic space group P2(1)/c, a = 6.034(2) Angstrom, b = 7.647(2) Angstrom, c = 10.162(3) Angstrom, beta = 92.931(6)degrees, and Z = 4. Ba3FeO5 crystallizes in the orthorhombic space group Pnma, with a = 10.301(1) Angstrom, b = 8.151(1) Angstrom, c = 7.611(1) Angstrom, and Z = 4. While both compounds feature discrete FeO44- tetrahedra, the anion found in Ba2FeO4 has shorter Fe-O bonds and is significantly distorted relative to the Ba3FeO5 anion, An iron valence of 4+ was confirmed by magnet susceptibility measurements and by the low-temperature isomer shifts of -0.152 and -0.142 mm/s relative to alpha-iron for Ba2FeO4 and Ba3FeO5, respectively. [less ▲]

Detailed reference viewed: 51 (0 ULg)
Full Text
Peer Reviewed
See detailFirst report on the presence in France of a B-chromosome polymorphism in Apodemus flavicollis
Ramalhinho, M. G.; Libois, Roland ULg

in Mammalia (2002), 66(2), 300-303

Observation of B chromosomes in Apodemus flavicollis in France (Massif central)

Detailed reference viewed: 17 (4 ULg)
Full Text
Peer Reviewed
See detailFracture prevention in postmenopausal women.
Bruyère, Olivier ULg; Edwards, John; Reginster, Jean-Yves ULg

in Clinical Evidence (2002), 8

Detailed reference viewed: 37 (23 ULg)
Full Text
Peer Reviewed
See detailSingle-domain antibody fragments with high conformational stability.
Dumoulin, Mireille ULg; Conrath, Katja; Van Meirhaeghe, Annemie et al

in Protein Science : A Publication of the Protein Society (2002), 11(3), 500-15

A variety of techniques, including high-pressure unfolding monitored by Fourier transform infrared spectroscopy, fluorescence, circular dichroism, and surface plasmon resonance spectroscopy, have been ... [more ▼]

A variety of techniques, including high-pressure unfolding monitored by Fourier transform infrared spectroscopy, fluorescence, circular dichroism, and surface plasmon resonance spectroscopy, have been used to investigate the equilibrium folding properties of six single-domain antigen binders derived from camelid heavy-chain antibodies with specificities for lysozymes, beta-lactamases, and a dye (RR6). Various denaturing conditions (guanidinium chloride, urea, temperature, and pressure) provided complementary and independent methods for characterizing the stability and unfolding properties of the antibody fragments. With all binders, complete recovery of the biological activity after renaturation demonstrates that chemical-induced unfolding is fully reversible. Furthermore, denaturation experiments followed by optical spectroscopic methods and affinity measurements indicate that the antibody fragments are unfolded cooperatively in a single transition. Thus, unfolding/refolding equilibrium proceeds via a simple two-state mechanism (N <--> U), where only the native and the denatured states are significantly populated. Thermally-induced denaturation, however, is not completely reversible, and the partial loss of binding capacity might be due, at least in part, to incorrect refolding of the long loops (CDRs), which are responsible for antigen recognition. Most interestingly, all the fragments are rather resistant to heat-induced denaturation (apparent T(m) = 60-80 degrees C), and display high conformational stabilities (DeltaG(H(2)O) = 30-60 kJ mole(-1)). Such high thermodynamic stability has never been reported for any functional conventional antibody fragment, even when engineered antigen binders are considered. Hence, the reduced size, improved solubility, and higher stability of the camelid heavy-chain antibody fragments are of special interest for biotechnological and medical applications. [less ▲]

Detailed reference viewed: 66 (14 ULg)
Full Text
Peer Reviewed
See detailLes "sans-papiers" et les régularisations dans l'Union Européenne à la lumière du cas belge
Martiniello, Marco ULg

in Revue des Affaires Européennes (2002), 11ème-12ème Année

Detailed reference viewed: 21 (4 ULg)
Full Text
Peer Reviewed
See detailExpression of TGF-betas and their receptors is differentially modulated by reactive oxygen species and nitric oxide in human articular chondrocytes.
Ayache, N.; Boumediene, K.; Mathy, Marianne ULg et al

in Osteoarthritis and Cartilage (2002), 10(5), 344-52

OBJECTIVES: To study the effects exerted by two antioxidants, N-monomethyl-L-arginine (L-NMMA), as an inhibitor of nitric oxide (NO) synthesis, and N-acetylcysteine (NAC), a reactive oxygen species (ROS ... [more ▼]

OBJECTIVES: To study the effects exerted by two antioxidants, N-monomethyl-L-arginine (L-NMMA), as an inhibitor of nitric oxide (NO) synthesis, and N-acetylcysteine (NAC), a reactive oxygen species (ROS) scavenger, on the expression of the major growth factor involved in cartilage repair, TGF-beta, under the three isoforms beta1, beta2 and beta3, and the receptors I and II of this factor, using lipopolysaccharide (LPS)-treated human chondrocytes in culture. METHODS: Suspension cultures of human chondrocytes derived from the knee of osteoarthritic patients were treated for 48 h with lipopolysaccharide (LPS) (10 microg/ml), L-NMMA (0.5 mM) or NAC (1 mM). Nitrite levels were assayed on the culture media using the Griess spectrophotometric method. After total RNA extraction, the expression of inducible NO synthase (iNOS), TGF-beta1, TGF-beta2, TGF-beta3, TGF-beta receptors I and II, was determined by semi-quantitative polymerase chain-reaction (RT-PCR). RESULTS: LPS induced a dramatic increase of both NO production and iNOS mRNA level. The addition of L-NMMA (0.5 mM) abolished NO production without affecting iNOS mRNA levels. In contrast NAC (1 mM) strongly synergized with LPS to stimulate NO synthesis. LPS treatment did not significantly alter TGF-beta1 expression whereas L-NMMA inhibited its production. TGF-beta2 mRNA level was decreased by LPS and was not changed in the presence of L-NMMA. On the other hand, NAC was capable of counteracting the LPS-induced inhibition of TGF-beta2 expression. TGFbeta3 mRNA level was markedly reduced by LPS alone, or with both L-NMMA and NAC. Finally, the expression of TGF-betaRI was slightly increased in the presence of combined LPS and L-NMMA or NAC whereas that of TGFbeta-RII was reduced in the same conditions. CONCLUSIONS: The modulation of TGF-beta system was found to be differentially controlled by NO and ROS productions. Indeed, the control exerted on TGF-beta expression varied according to the isoform: TGF-beta1 mRNA level depends on NO whereas that of TGF-beta2 is regulated by ROS and TGF-beta3 seems to be unaffected by both of them. The expression of TGF-beta receptors appeared to be modulated by NO and ROS levels. The relevance of the present findings to osteoarthritis (OA) physiopathology and the potential use of antioxidant therapy to treat this disease are discussed. [less ▲]

Detailed reference viewed: 53 (5 ULg)
Full Text
See detailLes lectures obligatoires en 5e année de l'enseignement secondaire de transition en Communauté française de Belgique
Lafontaine, Dominique ULg

in Enjeux : Revue de Formation Continuée et de Didactique du Français (2002), 55

Detailed reference viewed: 80 (3 ULg)
Full Text
Peer Reviewed
See detailComposite structures optimization using sequential convex programming
Bruyneel, Michaël ULg; Fleury, Claude ULg

in Advances in Engineering Software (2002), 33(7-10), 697-711

The design of composite structures is considered here. The approximation concepts approach is used to solve the optimization problem. The convex approximations of the MMA family are briefly described ... [more ▼]

The design of composite structures is considered here. The approximation concepts approach is used to solve the optimization problem. The convex approximations of the MMA family are briefly described. Several modifications of these approximations are presented. They are now based on gradient information at two successive iterations, avoiding the use of the expensive second-order derivatives. A two-point fitting scheme is also described, where the function value at the preceding design point is used to improve the approximation. Numerical examples compare these new purely non-monotonous schemes to the existing ones for the selection of optimal fibers orientations in laminates. It is shown how these two-point based approximations are well adapted to the problem and can improve the optimization task, leading to reasonable computational efforts. A procedure is also derived for considering simultaneously monotonous and non-monotonous structural behaviors. The resulting generalized approximation scheme is well suited for the optimization of composite structures when both plies thickness and fibers orientations are considered as design variables. It is concluded that the newly developed approximation schemes of the MMA family are reliable for composite structures optimization. All the studied approximations are convex and separable: the optimization problem can then be solved using a dual approach. (C) 2002 Civil-Comp Ltd and Elsevier Science Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 41 (2 ULg)
Full Text
See detailA propos d'immersion linguistique dans l'enseignement fondamental : un état de la question
Blondin, Christiane ULg; Straeten, M.

in Point sur la Recherche en Education (Le) (2002), 25

Detailed reference viewed: 398 (5 ULg)
Full Text
Peer Reviewed
See detailCultural characteristics, pathogenicity and vegetative compatibility of Fusarium udum isolates from pigeonpea (Cajanus Cajan (L.) Millsp.) in Kenya
Kiprop, E. K.; Mwang'Ombe, A. W.; Baudoin, Jean-Pierre ULg et al

in European Journal of Plant Pathology (2002), 108(2), 147-154

Detailed reference viewed: 46 (3 ULg)
Full Text
Peer Reviewed
See detailEnergy Balance Closure At Fluxnet Sites
Wilson, K.; Goldstein, A.; Falge, E. et al

in Agricultural and Forest Meteorology (2002), 113(1-4),

Detailed reference viewed: 24 (3 ULg)
Full Text
Peer Reviewed
See detailDevelopment Of A Visual Method To Quantify The Gossypol Content In Cotton Seeds
Benbouza, H.; Lognay, Georges ULg; Palm, Rodolphe ULg et al

in Crop Science (2002), 42(6), 1937-1942

Detailed reference viewed: 45 (6 ULg)
Full Text
Peer Reviewed
See detailGlobal democratic consensus on neuropathological disease criteria.
Achim, Cristian; Auer, Roland; Bergeron, Catherine et al

in Lancet Neurology (2002), 1(6), 340

Detailed reference viewed: 29 (1 ULg)
Full Text
See detailLes acteurs et les enjeux au coeur de l'évaluation
Vandoorne, Chantal ULg

in Education santé (2002), 173(173), 9-11

Detailed reference viewed: 83 (27 ULg)
Full Text
Peer Reviewed
See detailEffects of repetitive transcranial magnetic stimulation on visual evoked potentials in migraine.
Bohotin, V.; Fumal, Arnaud ULg; Vandenheede, M. et al

in Brain : A Journal of Neurology (2002), 125(Pt 4), 912-22

Between attacks, migraine patients are characterized by potentiation instead of habituation of stimulation-evoked cortical responses. It is debated whether this is due to increased or decreased cortical ... [more ▼]

Between attacks, migraine patients are characterized by potentiation instead of habituation of stimulation-evoked cortical responses. It is debated whether this is due to increased or decreased cortical excitability. We have studied the changes in visual cortex excitability by recording pattern-reversal visual evoked potentials (PR-VEP) after low- and high-frequency repetitive transcranial magnetic stimulation (rTMS), known respectively for their inhibitory and excitatory effect on the cortex. In 30 patients (20 migraine without, 10 with aura) and 24 healthy volunteers, rTMS of the occipital cortex was performed with a focal figure-of-eight magnetic coil (Magstim). Nine hundred pulses were delivered randomly at 1 or 10 Hz in two separate sessions. Stimulus intensity was set to the phosphene threshold or to 110% of the motor threshold if no phosphenes were elicited. Before and after rTMS, PR-VEP were averaged sequentially in six blocks of 100zztieresponses during uninterrupted 3.1 Hz stimulation. In healthy volunteers, PR-VEP amplitude was significantly decreased in the first block after 1 Hz rTMS and the habituation normally found in successive blocks after sustained stimulation was significantly attenuated. In migraine patients, 10 Hz rTMS was followed by a significant increase of first block PR-VEP amplitude and by a reversal to normal habituation of the potentiation (or dishabituation) characteristic of the disorder. This effect was similar in both forms of migraine and lasted for at least 9 min. There were no significant changes of PR-VEP amplitudes after 1 Hz rTMS in migraineurs and after 10 Hz rTMS in healthy volunteers, nor after sham stimulation. The recovery of a normal PR-VEP habituation pattern after high-frequency rTMS is probably due to activation of the visual cortex and the dishabituation in healthy volunteers to cortical inhibition. We conclude, therefore, that the deficient interictal PR-VEP habituation in migraine is due to a reduced, and not to an increased, pre-activation excitability level of the visual cortex. [less ▲]

Detailed reference viewed: 36 (8 ULg)
Full Text
Peer Reviewed
See detailRegulation by reactive oxygen species of interleukin-1beta, nitric oxide and prostaglandin E(2) production by human chondrocytes.
Mathy, Marianne ULg; Deby, Ginette ULg; Reginster, Jean-Yves ULg et al

in Osteoarthritis and Cartilage (2002), 10(7), 547-55

OBJECTIVES: To determine the effects of two drugs, N-monomethyl-L-arginine (L-NMMA) and N-acetylcysteine (NAC), on interleukin-1beta (IL-1beta), nitric oxide (NO) and prostaglandin E(2) (PGE(2 ... [more ▼]

OBJECTIVES: To determine the effects of two drugs, N-monomethyl-L-arginine (L-NMMA) and N-acetylcysteine (NAC), on interleukin-1beta (IL-1beta), nitric oxide (NO) and prostaglandin E(2) (PGE(2)) production by human chondrocytes. The effect of aceclofenac (ACECLO), a non-steroidal antiinflammatory drug (NSAID), was also examined. METHODS: Human chondrocytes were enzymatically isolated from osteoarthritic knee cartilage and then maintained in culture in suspension for 48h in the absence or in the presence of lipopolysaccharide (LPS) (10 microg/ml), L-NMMA (0.5mM), NAC (1mM) or ACECLO (6.10(-6)M). IL-1beta and PGE(2) productions were quantified by specific immunoassays. Nitrite was measured in the culture supernatants by a spectrophotometric method based upon the Griess reaction. Cyclooxygenase-2 (COX-2), inducible NO synthase (iNOS) and IL-1beta gene expressions were quantified by transcription of mRNA followed by real time and quantitative polymerase chain reaction. COX-2 protein expression was analysed by Western blot. RESULTS: LPS markedly increased the expression of IL-1beta, iNOS and COX-2 genes. In parallel, NO(2) and PGE(2) amounts found in the culture supernatants were significantly enhanced whereas IL-1beta was immunologically undetectable. The addition of L-NMMA (0.5mM) fully blocked LPS-induced NO production but greatly increased PGE(2) production, suggesting a negative effect of NO on PGE(2) synthesis. Inversely, NO production was stimulated by NAC while PGE(2) production was not affected. Interestingly, NAC increased the IL-1beta and iNOS mRNA levels but did not significantly modify COX-2 mRNA expression. L-NMMA did not significantly affect the expression of IL-1beta, iNOS and COX-2. The amount of COX-2 protein did not change in the presence of the antioxidants. Finally, ACECLO fully blocked the production of PGE(2) by chondrocytes without affecting the levels of COX-2 mRNA. CONCLUSIONS: The stimulation of IL-1beta, NO and PGE(2) production by LPS is differentially controlled by reactive oxygen species (ROS). In fact, L-NMMA and NAC have different mechanisms of action on the regulation of NO and PGE(2) productions. L-NMMA fully inhibits NO but increases PGE(2) production whereas NAC up-regulates NO but does not modify PGE(2) synthesis. The stimulating effect of L-NMMA on PGE(2) production is not controlled at the transcriptional level. These findings suggest that antioxidant therapy could have different effects according to the oxygen radical species targeted. [less ▲]

Detailed reference viewed: 39 (7 ULg)
Full Text
Peer Reviewed
See detailEtude longitudinale de l'hémodynamique artérielle mésentérique chez le nouveau-né prématuré stable en alimentation entérale
Battisti, Oreste ULg; Withofs, L.; Adant-François, A. et al

in Louvain Medical (2002), 121

Detailed reference viewed: 24 (9 ULg)
Full Text
Peer Reviewed
See detailPrediction of selectivity for enantiomeric separations of uncharged compounds by capillary electrophoresis involving dual cyclodextrin systems
Abushoffa, Adel M.; Fillet, Marianne ULg; Hubert, Philippe ULg et al

in Journal of Chromatography. A (2002), 948(1-2), 321-9

The single-isomer polyanionic cyclodextrin (CD) derivative heptakis-6-sulfato-beta-cyclodextrin (HSbetaCD) has been tested as chiral additive for the enantioseparation of non-steroidal anti-inflammatory ... [more ▼]

The single-isomer polyanionic cyclodextrin (CD) derivative heptakis-6-sulfato-beta-cyclodextrin (HSbetaCD) has been tested as chiral additive for the enantioseparation of non-steroidal anti-inflammatory drugs, such as fenoprofen, flurbiprofen, ibuprofen and ketoprofen, in capillary electrophoresis, using a pH 2.5 phosphoric acid-triethanolamine buffer in the reversed polarity mode. In most cases, the enantiomers of these acidic compounds, present in uncharged form at that pH, were only poorly resolved with HSbetaCD alone. However, the use of HSbetaCD in combination with the neutral CD derivative, heptakis-(2,3,6-tri-O-methyl)-beta-cyclodextrin (TMbetaCD), which has a particularly high enantioselectivity towards these compounds, has led to complete enantioresolution in reasonably low migration times in most cases. Affinity constants for the enantiomers with the two cyclodextrins were determined, using linear regression in a two-step approach. Affinity constants with the charged HSbetaCD were first calculated in single systems while those with the neutral TMbetaCD were determined in dual systems. Selectivity for the enantiomeric separation of these compounds in dual CD systems could be predicted using recently developed mathematical models. [less ▲]

Detailed reference viewed: 57 (15 ULg)
Full Text
Peer Reviewed
See detailChemical changes and influences of rapeseed antinutritional factors on gestating and lactating ewes 1. Animal performances and plasma hormones and glucose
Mandiki, S. N. M.; Derycke, G.; Bister, J. L. et al

in Animal Feed Science & Technology (2002), 98(1-2), 25-35

An experiment was carried out in order to study the effects of high levels of low-glucosinolates (LG)-rapeseed meal of two varieties (Apex or Synergy) on ewes and lambs performances and circulating ... [more ▼]

An experiment was carried out in order to study the effects of high levels of low-glucosinolates (LG)-rapeseed meal of two varieties (Apex or Synergy) on ewes and lambs performances and circulating hormones (progesterone-P4, estradiol-E2,-prolactin-PRL, cortisol, insulin, tri-iodothyronin-T3, thyroxin-T4) and glucose. On the 100th day of gestation, 90 ewes bearing at least two foetuses were divided into 3 groups. Control, Apex and Synergy groups received concentrates with 0, 40 and 40% of LG-rapeseed meal obtained with either Apex (13.77 mumol of glucosinolates/g DM seed) or Synergy (18.19 mumol) variety. Apart from the distribution of pasture hay ad libitum, the ewes received 500 and 1200 g of concentrates/animal per day during gestation and lactation, respectively. Concentrates were offered till the 47th day of lactation, and thereafter, the ewes were fed only with hay during 3 weeks. The lambs received ad libitum concentrates without rapeseed meal from 10 days of age till slaughtering. They were weaned at 65 days of age and were slaughtered when their fattening state was optimal. The performances of ewes (food intake and liveweight profiles) and of lambs (birth liveweight, mortality at birth, weight gains, slaughtering parameters) were not reduced by 40% of LG-rapeseed meal except a decrease in the liveweight for ewes in the Apex group after lambing. The profiles and levels of plasma metabolic (T3, T4, cortisol, insulin) and reproductive (PRL, P4) hormones were not modified by the rapeseed meal. In contrast, the estradiol concentration was lower (P < 0.05) in the two groups of ewes which received rapeseed meal than in the controls as an index of an eventual disturbance in the reproductive functions. In conclusion, large amounts of LG-rapeseed meal may be used as protein supplement in the diet of ewes at the end of gestation and during lactation without negative effects on animal performances and physiology. (c( 2002 Published by Elsevier Science B.V. [less ▲]

Detailed reference viewed: 88 (16 ULg)
Full Text
Peer Reviewed
See detailLe médecin du travail face au harcèlement moral au travail : constats et prespectives
Gruslin, Isabelle ULg; Italiano, Patrick ULg; Faulx, Daniel ULg

in Médecine du Travail & Ergonomie= Arbeidsgezondheidszorg & Ergonomie (2002), 39(2), 61-68

L'article de D. Faulx et C. Geuzaine, paru dans le numéro 3-2000 de cette revue, aborde l'étendue du phénomène du harcèlement moral ainsi que les aspects juridiques de la définition, la description du ... [more ▼]

L'article de D. Faulx et C. Geuzaine, paru dans le numéro 3-2000 de cette revue, aborde l'étendue du phénomène du harcèlement moral ainsi que les aspects juridiques de la définition, la description du processus, ses conséquences médicales et les facteurs de risque. Dans la suite de cette étude, nous présentons ici les résultats d'une enquête menée auprès des médecins du travail, en tant que témoins et intervenants privilégiés dans le domaine du harcèlement. Cette enquête vise à apporter des informations descriptives originales concernant les attitudes, les opinions et représentations des médecins du travail par rapport au phénomène de harcèlement moral. En outre, elle est l'occasion de tester une série d'hypothèses sur les facteurs pouvant influencer l'attitude des médecins du travail vis-à-vis du harcèlement moral. [less ▲]

Detailed reference viewed: 403 (24 ULg)
Full Text
Peer Reviewed
See detailMaladie de Horton et atteintes arterielles extratemporales: utilite de la tomographie par emission de positons au 18FDG. A propos de trois observations et d'une revue de la litterature
Belhocine, Tarik; Kaye, Olivier; Delanaye, Pierre ULg et al

in Revue de Médecine Interne (2002), 23(7), 584-91

PURPOSE: We report three cases of Horton's disease, in which F18-Fluorine-2-Deoxy-D-Glucose (18FDG) positron emission tomography (PET) demonstrated a clinically unsuspected extra-cranial vessels ... [more ▼]

PURPOSE: We report three cases of Horton's disease, in which F18-Fluorine-2-Deoxy-D-Glucose (18FDG) positron emission tomography (PET) demonstrated a clinically unsuspected extra-cranial vessels hypermetabolism. METHODS: Fully corrected whole-body PET was performed in three patients (two women, one man) for exploring a marked inflammatory syndrome. Scanning was acquired 60 min after i.v. injection of 222 MBq of 18FDG in average. RESULTS: In two patients with histologically proven Horton's disease, PET alone showed increased glucose metabolism involving the carotid and sub-clavian arteries as well as the ascending aorta, aortic arch, thoracic and abdominal aorta, and the iliac and femoral arteries. In the third patient, by detecting cervical, thoracic and abdominal vessel hypermetabolism, PET non-invasively contributed to the diagnosis of giant cell arteritis. All patients had complete clinical and biological response to corticoids. PET controls performed 3- to 6-months post-treatment, confirmed the disappearance of the metabolic stigma. CONCLUSION: 18FDG PET may show an increased glucose metabolism in asymptomatic extracranial vessels locations of Horton's arterities. If these observations are confirmed on controlled trials, PET could be particularly useful for non-invasive diagnosing, staging and monitoring atypical clinical forms of Horton's disease. The metabolic imaging could also contribute to a better understanding of the pathogenesis of GCA. [less ▲]

Detailed reference viewed: 222 (10 ULg)
Full Text
Peer Reviewed
See detailImproving the performance of low-gain designs for bounded control of linear systems
Grognard, F.; Sepulchre, Rodolphe ULg; Bastin, G.

in Automatica (2002), 38(11), 1777-1782

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailLa régulation des services publics: les enseignements du droit comparé
Thirion, Nicolas ULg

in Chroniques de Droit Public = Publiekrechtelijke Kronieken (2002), 4

Detailed reference viewed: 38 (11 ULg)
Full Text
Peer Reviewed
See detailLa gestion des eaux par bassins hydrographiques
Pâques, Michel ULg; Leprince, Sylviane ULg

in Aménagement - Environnement (2002)

Detailed reference viewed: 54 (12 ULg)
Full Text
Peer Reviewed
See detailEvolution des donnees maternelles et perinatales recueillies en routine entre 1980 et 1998 a la maternite de reference de Rutshuru en Republique democratique du Congo. II. Deces du nouveau-ne et naissances de faible poids.
Mugisho, Etienne; Dramaix, Michele; Porignon, Denis ULg et al

in Sante (Montrouge, France) (2002), 12(2), 252-5

This second paper aims at deriving useful information allowing to improve the strategy applied for maternal health care. MATERIAL AND METHODOLOGY: Between 1980 and 1998, data on 13,042 deliveries were ... [more ▼]

This second paper aims at deriving useful information allowing to improve the strategy applied for maternal health care. MATERIAL AND METHODOLOGY: Between 1980 and 1998, data on 13,042 deliveries were collected. Characteristics, mortality, morbidity of mothers and new-born and obstetrical interventions were recorded. The present work describes the evolution of low birth weight (LBW), new-born deaths, and associated risk factors. The statistical analyses applied included khi2, t-test, and multiple logistic regression. RESULTS: Eighteen percent of new-born weights below 2.5 kg and 7.9% died. The proportion of low birth weights remains globally constant. Low proportions of new-born deaths were observed in 1981, 1982, 1988 and 1998. At admission, 35% of the women presented at least one of the four risks defined by the factors used for reference; this proportion went up from 26.1 to 39.2%. The four reference factors were associated with low birth weight. Baudelocque diameter and age were not associated with new-born death. Education and BMI were associated with an increased risk of new-born death. Marital status was not associated with any of the two outcomes. CONCLUSION: This analysis shows small variation of LBWs and perinatal deaths. It confirms the association between these two outcomes and most of the risk factors studied. The efficacy of the strategies implemented for improving perinatal health is questioned. The authors recommend that they be reassessed. [less ▲]

Detailed reference viewed: 13 (3 ULg)
Full Text
See detailLe GPS et la Physique
Garnir, Henri-Pierre ULg; Strivay, David ULg; Bastin, Thierry ULg

in Science and Culture (2002), 380

Detailed reference viewed: 35 (6 ULg)
Full Text
Peer Reviewed
See detailRecommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma
Holgate, ST; Bousquet, J; Chung, KF et al

in International Journal of Pharmaceutical Medicine (2002), 16

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailEffects of incidental and intentional feature binding on recognition: a behavioural and PET activation study
Lekeu, Françoise ULg; Van der Linden, Martial ULg; Collette, Fabienne ULg et al

in Neuropsychologia (2002), 40(2), 131-144

Using Positron Emission Tomography (PET), we investigated cerebral regions associated with the episodic recognition of words alone and words bound to contextual colours. Two modes of colour encoding were ... [more ▼]

Using Positron Emission Tomography (PET), we investigated cerebral regions associated with the episodic recognition of words alone and words bound to contextual colours. Two modes of colour encoding were tested: incidental and intentional word-to-colour binding. Word-only recognition was associated with brain activation in a lexico-semantic left middle temporal region and in the cerebellum following an incidental colour encoding, and with brain activation in the left posterior middle frontal gyrus, right anterior cingulate and right inferior frontal gyrus following an intentional encoding. Recognition of bound features was associated with activation in left prefrontal and superior parietal regions following an incidental colour encoding, and with preferential right prefrontal cortex activation following an intentional colour encoding. Our results are in line with the hypothesis of a parietal involvement in context processing, and prefrontal areas in monitoring retrieval processes. Our results also support the hypothesis of a 'cortical asymmetry for reflective activity' (CARA). [less ▲]

Detailed reference viewed: 54 (5 ULg)
Full Text
See detailLes figures féminines dans le théâtre de Jean-Marie Piemme
Delhalle, Nancy ULg

in Alternatives Théâtrales (2002), (75),

Detailed reference viewed: 31 (3 ULg)
Full Text
Peer Reviewed
See detailCharacterization of porous texture of hyperporous materials by mercury porosimetry using densification equation
Pirard, René ULg; Alié, Christelle ULg; Pirard, Jean-Paul ULg

in Powder Technology (2002), 128(2-3), 242-247

The purpose of this paper is to propose a method of analyzing the mercury porosimetry data in the case of materials called hyperporous. This class of material does not undergo intrusion by mercury ... [more ▼]

The purpose of this paper is to propose a method of analyzing the mercury porosimetry data in the case of materials called hyperporous. This class of material does not undergo intrusion by mercury; instead, it shrinks under the mercury isostatic pressure and its density increases. The phenomenon is partially or completely irreversible. The proposed method enables computing the pore volume distribution as a function of the pore size in the same way as Washburn's method does in the case of mercury intrusion. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

Detailed reference viewed: 45 (9 ULg)
Full Text
Peer Reviewed
See detailPierre Bourdieu: une sociologie de la désespérance/ paradigme économique, lutte de pouvoir et "violence inerte"
Robert, Jocelyne ULg

in Revue de l'Institut de Sociologie (2002), 1-4

Detailed reference viewed: 70 (15 ULg)
Full Text
Peer Reviewed
See detailIn vivo manganese-enhanced magnetic resonance imaging reveals connections and functional properties of the songbird vocal control system
Van der Linden, A.; Verhoye, M.; Van Meir, V. et al

in Neuroscience (2002), 112(2), 467-474

Injection of manganese (Mn2+), a paramagnetic tract tracing agent and calcium analogue, into the high vocal center of starlings labeled within a few hours the nucleus robustus archistriatalis and area X ... [more ▼]

Injection of manganese (Mn2+), a paramagnetic tract tracing agent and calcium analogue, into the high vocal center of starlings labeled within a few hours the nucleus robustus archistriatalis and area X as observed by in vivo magnetic resonance imaging. Structures highlighted by Mn2+ accumulation assumed the expected tri-dimensional shape of the nucleus robustus archistriatalis and area X as identified by classical histological or neurochemical methods. The volume of these nuclei could be accurately calculated by segmentation of the areas highlighted by Mn2+. Besides confirming previously established volumetric sex differences, Mn2+ uptake into these nuclei revealed new functional sex differences affecting Mn2+ transport. A faster transport was observed in males than in females and different relative amounts of Mn2+ were transported to nucleus robustus archistriatalis and area X in males as compared to females. This new in vivo approach, allowing repeated measures, opens new vistas to study the remarkable seasonal plasticity in size and activity of song-control nuclei and correlate neuronal activity with behavior. It also provides new insights on in vivo axonal transport and neuronal activity in song-control nuclei of oscines. (C) 2002 IBRO. Published by Elsevier Science Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 44 (1 ULg)
Full Text
Peer Reviewed
See detailNonlinear thin shell finite element for steel and concrete structures subjected to fire: theoretical development
Talamona, Didier; Franssen, Jean-Marc ULg

in Journal of Applied Fire Science (2002), 11(4), 291-310

This article describes the features of a quadrilateral thin shell element, based on Marguerre's theory that has ben implemented in the finite element program SAFIR (from the University of Liege.) The ... [more ▼]

This article describes the features of a quadrilateral thin shell element, based on Marguerre's theory that has ben implemented in the finite element program SAFIR (from the University of Liege.) The element has four nodes (one at each corner) and each node has six degrees of freedom, i.e., three translations and three rotations (the sixth degree of freedom is a true one, which can be assimilated to the in-plane rotation.) This article presents some theoretical developments regarding the element formulation. The algorithm strategies for isotropic material (steel for example) and non-isotropic material 'concrete) and their modifications for elevated temperatures are described. Two verifications examples are presented (the patch test and Lee's frame at elevated temperatures). [less ▲]

Detailed reference viewed: 73 (4 ULg)
Full Text
Peer Reviewed
See detailRapid And Homogenous Detection Of Apple Stem Pitting Virus By Rt-Pcr And A Fluorogenic 3 ' Minor Groove Binder-Dna Probe
Salmon, Marc ULg; Vendrame, Marina; Kummert, Jean et al

in European Journal of Plant Pathology (2002), 108(8), 755-762

Detailed reference viewed: 36 (3 ULg)
Full Text
Peer Reviewed
See detailIn situ dynamic analysis of solid or aqueous solutions undergoing chemical reactions by RBS or PIXE with external beam
Bouquillon, A.; Dran, J*-C; Lagarde, G. et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2002), 188

Detailed reference viewed: 12 (3 ULg)
Full Text
Peer Reviewed
See detailCoalescence of secondary dispersions in fiber beds
Speth, Hauke; Pfennig, Andreas ULg; Chatterjee, Michael et al

in Separation and Purification Technology (2002), 29(2), 113-119

Detailed reference viewed: 17 (6 ULg)
Full Text
Peer Reviewed
See detailA copula based model for multivariate non normal longitudinal data: analysis of a dose titration safety study on a new antidepressant
Lambert, Philippe ULg; Vandenhende, François

in Statistics in Medicine (2002), 21

A new model for multivariate non-normal longitudinal data is proposed. In a first step, each longitudinal series of data corresponding to a given response is modelled separately using a copula to relate ... [more ▼]

A new model for multivariate non-normal longitudinal data is proposed. In a first step, each longitudinal series of data corresponding to a given response is modelled separately using a copula to relate the marginal distributions of the response at each time of observation. In a second step, at each observation time, the conditional (on the past) distributions of each response are related using another copula describing the relationship between the corresponding variables. Note that there is no need to consider the same family of distributions for these response variables. The technique is illustrated in a dose titration safety study on a new antidepressant. The haemodynamic effect on diastolic blood pressure, systolic blood pressure and heart rate is studied. These three responses are measured repeatedly over time on ten healthy volunteers during the dose escalation. The available covariates are sex and the concentration of drug in the plasma at time of measurement. [less ▲]

Detailed reference viewed: 43 (4 ULg)
Full Text
Peer Reviewed
See detailDevelopment of GEQUAC as a new group contribution method for strongly non-ideal mixtures
Ehlker, Gerhard H; Pfennig, Andreas ULg

in Fluid Phase Equilibria (2002), 203((1-2)), 53-69

Detailed reference viewed: 24 (2 ULg)
Full Text
Peer Reviewed
See detailL'engoument pour la "Cène" de Léonard de Vinci à la cour de France, sous les règnes de Louis XII et de François Ier
Fagnart, Laure ULg

in Bulletin des amis du château et des musées de Blois (2002), 33

Cette contribution présente les copies de la "Cène" de Léonard de Vinci qui ont été réalisées à la demande de Français dans la première moitié du XVIe siècle. Elle s’attache à comprendre comment et ... [more ▼]

Cette contribution présente les copies de la "Cène" de Léonard de Vinci qui ont été réalisées à la demande de Français dans la première moitié du XVIe siècle. Elle s’attache à comprendre comment et pourquoi autant de Français, souvent en poste dans l’administration française à Milan, ont commandé des copies du chef-d’œuvre du maître italien, définissant de ce fait les mécanismes de l’engouement pour la peinture murale à la cour de France, sous les règnes de Louis XII et de François Ier. [less ▲]

Detailed reference viewed: 98 (9 ULg)
Full Text
Peer Reviewed
See detailMass transfer by free and forced convection from single spherical liquid drops
Waheed, M Adekojo; Henschke, Martin; Pfennig, Andreas ULg

in International Journal of Heat & Mass Transfer (2002), 45(22), 4507-4514

Detailed reference viewed: 18 (0 ULg)
Full Text
Peer Reviewed
See detailCanopy gap edge determination and the importance of gap edges for plant diversity
Salvador-Van Eysenrode, D; Kockelbergh, F; Bogaert, Jan ULg et al

in Web Ecology (2002), 3

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailDNA sequences coding for the F18 fimbriae and AIDA adhesin are localized on the same plasmid in Escherichia coli isolates from piglets
Mainil, Jacques ULg; Jacquemin, E.; Pohl, P. et al

in Veterinary Microbiology (2002), 86

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailEcology of Salmonella in slaughter pigs digestive tract and study of the contamination of carcasses
Boudry, Christelle ULg; Korsak Koulagenko, Nicolas ULg; Jacob, Benoit et al

in Annales de Médecine Vétérinaire (2002), 146(6, DEC-JAN), 353-360

This article presents a study on the Salmonella asymptomatic carriage of finishing pigs and its consequences on the contamination of carcasses. Twenty finishing pigs were followed to determine the faecal ... [more ▼]

This article presents a study on the Salmonella asymptomatic carriage of finishing pigs and its consequences on the contamination of carcasses. Twenty finishing pigs were followed to determine the faecal shedding of Salmonella. No sample was positive but at the slaughterhouse, the analysis of tonsils and certain parts of the digestive tract (mesenterial lymph nodes, ileum and large intestine content) revealed that 70% of the pigs were positive. The strains isolated from the faecal samples of the large intestine and from tonsils were identical, which might indicate that there has been an oral contamination from pig to pig due to the shedding of Salmonella or a carriage of different strains in different organs. The mesenterial lymph nodes (40 % positive) were contaminated by strains which were different from those from the faecal samples and tonsils. Salmonella strains were only found on the swabs of one carcass. A complementary assay has shown the negative role played by the scalding step. This latter may contaminate the oral and rectal cavities of slaughtered animals. This entire study reveals the difficulty to predict the contamination risk at the slaughterhouse from the analysis of finishing pigs faecal samples. Therefore, a better knowledge of the carriage and the shedding of Salmonella during the finishing period and during the slaughter is necessary to minimise meat contamination. [less ▲]

Detailed reference viewed: 200 (53 ULg)
Full Text
Peer Reviewed
See detailVegetation composition of a threatened hypersaline lake (Lake Bardawil), North Sinai
El-Bana, M I; Khedr, A-H A; Van Hecke, P et al

in Plant Ecology (2002), 163(1), 63-75

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailOral antivirals revisited in the treatment of herpes zoster: what do they accomplish?
Nikkels, Arjen ULg; Pierard, Gérald ULg

in American Journal of Clinical Dermatology (2002), 3(9), 591-8

Oral antiviral agents currently represent the most important therapeutic keystone in the treatment of herpes zoster. Three oral antiviral agents are available for the treatment of herpes zoster: acyclovir ... [more ▼]

Oral antiviral agents currently represent the most important therapeutic keystone in the treatment of herpes zoster. Three oral antiviral agents are available for the treatment of herpes zoster: acyclovir, its derivative valacyclovir, and famciclovir. Meta-analysis of published data has shown that oral acyclovir significantly reduces various herpes zoster-related symptoms as well as the duration, intensity and prevalence of zoster-associated pain (ZAP). However, this drug does not influence postherpetic neuralgia. The newer agents famciclovir and valacyclovir exhibit a better oral bioavailability than acyclovir. These agents have demonstrated similar efficacy to acyclovir with ZAP and they require less frequent administration. When initiated within 72 hours, oral antiviral therapy of herpes zoster is beneficial in selected, elderly immunocompetent patients, reducing the duration and intensity of ZAP and providing more rapid skin lesion healing. Oral antivirals are also of benefit in immunocompromised patients with uncomplicated herpes zoster. However, signs of cutaneous and visceral dissemination should be monitored; if signs occur, intravenous antiviral therapy is indicated. [less ▲]

Detailed reference viewed: 38 (4 ULg)
Full Text
Peer Reviewed
See detailGenetic diversity of the african geocarpic legume kersting's groundnut, Macrotyloma geocarpum (Tribe Phaseoleae : Fabaceae)
Pasquet, R. S.; Mergeai, Guy ULg; Baudoin, Jean-Pierre ULg

in Biochemical Systematics & Ecology (2002), 30(10), 943-952

Detailed reference viewed: 65 (5 ULg)
Full Text
Peer Reviewed
See detailWave packet propagation for constrained molecular systems. Spectroscopic applications to triatomic molecules
Lauvergnat, David; Justum, David; Desouter, Michèle ULg et al

in Journal of Molecular Structure : Theochem (2002), 577

Detailed reference viewed: 14 (0 ULg)