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See detailCombined Ring Inversion and Side Group Rotation in Geminal Diphosphoryl Substituted Pyrrolinoxyl Radicals: ESR Analysis of Chemical Exchange between Four Nonequivalent Sites
Rockenbauer, Antal; Mercier, Anne; Le Moigne, François et al

in Journal of Physical Chemistry A (1997), 101(43), 7965-7970

The ESR spectra of three diphosphorylated pyrrolidinoxyl radicals have been studied over a large temperature range. While for the trans 2,5-disubstituted compound 1 no line width alternation was found ... [more ▼]

The ESR spectra of three diphosphorylated pyrrolidinoxyl radicals have been studied over a large temperature range. While for the trans 2,5-disubstituted compound 1 no line width alternation was found, for the 2,2-disubstituted compounds 2 and 3, dramatic changes in the spectra were observed as a function of the temperature. These changes were explained by a four-site chemical exchange model including both ring inversion and hindered rotation around the carbon-phosphorus bonds. For radical 3, the presence of additional 5,5-dimethyl substitution can completely block rotations around carbon-phosphorus bonds for certain ring geometries, while for other ring conformations chemical exchange still occurs through combined inversionrotation processes. An effective two-site model composed of nonequivalent sites and a superposition model composed of a pair of exchanging conformers and a pair of nonexchanging conformers were used to simulate spectrum variations. A satisfactory fit was obtained over the entire temperature range investigated. From the temperature dependence of the exchange frequencies the potential barriers for ring inversion (27 kJ/mol), for combined inversion-rotation (11 kJ/mol), and for rotation around the carbon-phosphorus bonds (14 kJ/mol) were estimated. [less ▲]

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See detailGluonic content of the scalar meson nonet in a scaled effective Lagrangian
Jaminon, Martine ULg; Van den Bossche, Bruno

in Nuclear Physics A (1997), 619

A scaled SU(3) Nambu-Jona-Lasinio Lagrangian is used to compute the mass of the nine scalar mesons in the vacuum and the mass of the glueball. This chiral model provides a gluonic content to the scalar ... [more ▼]

A scaled SU(3) Nambu-Jona-Lasinio Lagrangian is used to compute the mass of the nine scalar mesons in the vacuum and the mass of the glueball. This chiral model provides a gluonic content to the scalar mesons as well as a quark content to the glueball. It is shown that a suitable choice of the vacuum gluon condensate allows reproduction of the experimental masses of the scalar mesons except for K*0(1430). This choice corresponds to a weak coupling between the gluon and quark condensates, giving f0(1500) or fJ(1710) which is nearly a pure glueball. [less ▲]

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See detailThe impact of sperm precedence in malathion resistance transmission in populations of the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae)
Haubruge, Eric ULg; Arnaud, Ludovic; Mignon, Jacques ULg

in Journal of Stored Products Research (1997), 33(2), 143-146

Malathion resistance in the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) is actually a worldwide problem, and studies on resistance transmission are needed to improve ... [more ▼]

Malathion resistance in the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) is actually a worldwide problem, and studies on resistance transmission are needed to improve insecticide resistance management. Females of Tribolium castaneum commonly mate with several males, and the last batch of male sperm preferentially fertilizes subsequent eggs. This phenomenon, a particular form of sexual selection, helps to increase resistance transmission in populations of stored product insects. We confirmed the last male sperm precedence and, in the absence of further matings, examined the evolution of mixed susceptible and malathion-resistant progeny during a 3-month period. The proportion of resistant phenotypes in female progeny was 99.6 and 3%, respectively, after the first mating with a resistant male and the second mating with a susceptible one. When females thus mated twice were isolated from males, the proportion of the resistant phenotype increased to 34.1% after 30 days. From 72 days onwards, this proportion ranged from 14.2 to 29.7%. (C) 1997, Published by Elsevier Science Ltd. [less ▲]

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See detailDifférences entre les pathotypes et les sérogroupes des Escherichia coli vérotoxinogènes isolées de veaux sains et celles isolées de veaux souffrant de diarrhée
Pohl, P.; Cleenwerk, I.; Imberechts, H. et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailTrajectoire déviante à la lisière entre adolescence et âge adulte
Gavray, Claire ULg

in Déviance et Société (1997), 21(3), 273-288

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See detailAu fil du fleuve. Entretien avec Luc et Jean-Pierre Dardenne
Mélon, Marc-Emmanuel ULg; d'Autreppe, Emmanuel; Flamant, Nathalie et al

in Revue belge du cinéma (1997), 41

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See detailThe Nucleotide Sequence Of Saccharomyces Cerevisiae Chromosome XII
Johnston, M.; Hillier, L.; Riles, L. et al

in Nature (1997), 387(6632),

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See detailEffects of meloxicam compared to acetylsalicylic acid in human articular chondrocytes
Bassleer, Corinne; Magotteaux, Jacques ULg; Geenen, Vincent ULg et al

in Pharmacology (1997), 54

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See detailLoss of type IV collagen alpha 5 and alpha 6 chains in human invasive prostate carcinomas
Dehan, Pierre ULg; Waltregny, David ULg; Beschin, Alain et al

in American Journal of Pathology (1997), 151(4), 1097-104

Type IV collagen, a major component of basement membranes, is organized in a network responsible for the mechanical resistance of the basement membranes. It also plays a key role in epithelial cell ... [more ▼]

Type IV collagen, a major component of basement membranes, is organized in a network responsible for the mechanical resistance of the basement membranes. It also plays a key role in epithelial cell adhesion to basement membranes. This study was designed to investigate the distribution of type IV collagen alpha-chains in normal, preneoplastic, and malignant prostate basement membranes. For this purpose, immunohistochemistry using specific antibodies raised against the different alpha-chains of type IV collagen was performed in eight normal samples, six prostatic intraepithelial neoplasia, and 20 malignant lesions of the prostate. Our results demonstrate the presence of the "novel" alpha 5 (IV) and alpha 6 (IV) chains along with the "classical" alpha 1 (IV)/alpha 2 (IV) chains in the basement membrane of the normal prostate gland. The alpha 3 (IV) chain was never detected in any prostate specimen. Prostatic intraepithelial neoplasia showed a similar immunostaining pattern to that found in normal glands. In cancer gland basement membranes, we demonstrate for the first time a specific loss of the alpha 5 (IV) and alpha 6 (IV) chains, whereas the classical alpha 1 (IV) and alpha 2 (IV) chains were consistently exhibited. Additionally, type VII collagen colocalized with alpha 5 (IV) collagen chain, and these two proteins, which were always observed in normal and prostatic intraepithelial neoplasia gland basement membranes, were lost in invasive carcinoma basement membranes. This observation raises questions about the possible association or cooperation between alpha 5 (IV)/alpha 6 (IV) chains and anchoring fibrils in prostate glands basement membrane. [less ▲]

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See detailA 12 Kb Nucleotide Sequence Containing The Alanine Dehydrogenase Gene At 279 Degrees On The Bacillus Subtilis Chromosome
Oudega, B.; Vandenbol, Micheline ULg; Koningstein, G.

in Microbiology-Uk (1997), 143

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See detailLa rhinotrachéite infectieuse bovine : caractéristiques du virus, l'infection et ses manifestations cliniques
Thiry, Etienne ULg; Lemaire, Mylène; Vanderheijden, Nathalie et al

in Bulletin des Groupements Techniques Vétérinaires (1997), 568

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See detailThe Cloning And Sequencing Of An Ovine C-Myc Cdna
Kiermer, V.; Dequiedt, Franck ULg; Masengo, R. et al

in DNA Sequence : The Journal of DNA Sequencing & Mapping (1997), 7(3-4),

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See detailLes rideaux de Magritte
Steinmetz, Rudy ULg

in Degrés : Revue de Synthèses à Orientation Sémiologique (1997)

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See detailDiagenetic and paleogeographic significance of clay and other sedimentary components in the middle Devonian limestones of Western Ardennes, France
Chamley, H.; Proust, J. N.; Mansy, J. L. et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (1997), 129

Givetian deposits accumulated in a more than 300-m-thick succession on a carbonate platform developed on the passive margin of the so-called Rheic ocean. These rocks crop out in the Ardenne massif at ... [more ▼]

Givetian deposits accumulated in a more than 300-m-thick succession on a carbonate platform developed on the passive margin of the so-called Rheic ocean. These rocks crop out in the Ardenne massif at Glageon in a structural context marked by small fault-controlled basins subjected to moderate overburden, tectonic and metamorphic constraints. Data on the clay mineral distribution, associated with detailed information on limestone facies/microfacies, as well as data on the depositional profile and sequence stratigraphic evolution of these rocks indicate strong carbonate diagenesis and moderate clay diagenesis, the latter being favoured by the early occurrence of the former, which prevented further fluid-rock interaction. The clay assemblage distribution, which roughly parallels the palaeomorphologic and palaeobathymetric shape of the Givetian continental margin, is organized in five successive zones indicating large-scale sequence stratigraphic evolution and the control of regional sea-level fluctuations. The clay and other sedimentary components provide additional information on the warm and variably humid climate, northern, relative to southern, terrigenous sources, the open sea relative to restricted depositional environments, the temporary tectonic rejuvenation of the continental hinterland and the chemical conditions allowing early diagenetic modifications. [less ▲]

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See detailEtude clinique et anatomopathologique de l'infection expérimentale de lapins par une souche virale amyxomateuse isolée en Belgique
Marlier, Didier ULg; Coignoul, Freddy ULg; Boucraut-Baralon, Corine et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailGrecs, Romains et Barbares. A la recherche de l'identité ethnique et linguistique des Grecs et des Romains
Rochette, Bruno ULg

in Revue Belge de Philologie et d'Histoire (1997), 75

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See detailFreeze-dried resorcinol-formaldehyde gels
Blacher, Silvia ULg; Pirard, René ULg; Pirard, Jean-Paul ULg et al

in Journal of Non-Crystalline Solids (1997), 212(2-3), 250-261

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer ... [more ▼]

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer to micrometer length-scale. Taking a standard freezing rate, we study in detail the influence of the molar ratio resorcinol/catalyst on the texture, This molar ratio is one of the parameters under consideration which can lead to a tailoring of the dried gel texture in order to develop adsorbents or catalyst supports of controlled porosity. Characterization methods include nitrogen adsorption-desorption (including the classical and the fractal interpretations), mercury porosimetry, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and small angle X-ray scattering (SAXS). [less ▲]

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See detailLes armées d'Alexandre le Grand et les langues étrangères
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1997), 66

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See detailLa cartographie des hydrophytes appliquée à l'étude des écosystèmes fluviaux: un outil d'analyse pour la restauration des anciens chenaux rhénans
Klein, J. P.; Vanderpoorten, Alain ULg; Sanchez-Perez, J. et al

in Lejeunia, Revue de Botanique (1997), 153

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See detailLes moyens de se prémunir contre la défaillance de ses cocontractants
Georges, Frédéric ULg

in Actualités du Droit (1997)

Cette contribution commentait l'impact de la réforme de 1997 du droit de l'insolvabilité sur les droits des créanciers

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See detailNutrient utilisation and particulate organic matter changes during summer in the upper mixed layer (Ross Sea, Antarctica).
Catalano, Giulio; Povero, Paolo; Fabiano, Mauro et al

in Deep-Sea Research Part I, Oceanographic Research Papers (1997), 44(1), 97-112

The relationships among vertical stability, estimated nutrient utilisation and particulate organic matter in the Ross Sea are analysed from data collected during two cruises in the summers of 1987 - 88 ... [more ▼]

The relationships among vertical stability, estimated nutrient utilisation and particulate organic matter in the Ross Sea are analysed from data collected during two cruises in the summers of 1987 - 88 and 1989 - 90. In the upper mixed layer (UML), identified through the vertical stability E(Z(UML)), nutrient consumption is calculated as the difference between the « diluted » nutrient value and the mean calculated from the integrated value in the UML. The nutrient utilisation ratio and E(Z(UML)) are linearly related for E(Z(UML)) < 25, whereas for values > 25, the distribution pattern is more scattered and independent of E(Z(UML)). For E(Z(UML)) > 25, utilisation values were > 4, 0.4 and 10 mmol m-3 for nitrate, phosphate and silicate, respectively. Significant relationships between nutrient depletion and both particulate organic carbon (POC) and particulate protein / particulate carbohydrate ratios (PPRT/PCHO) are found. The analysis of particulate matter distribution vs nutrient utilisation shows that the stations could be divided into two groups having different characteristics. The first group includes coastal stations, where high nutrient utilisation, POC and PPRT / PCHO are typical of areas with high production. In the second group (pelagic stations), nutrient utilisation, POC and PPRT / PCHO are lower. The vertical stability can be used to discriminate among the factors that influence primary production. [less ▲]

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See detailRoma ou Ruma ?
Rochette, Bruno ULg

in Maia (1997), 49

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See detailScintigraphic visualization of intrathecal liposome biodistribution.
Umbrain, V; D'Haese, J; Alafandy, M et al

in Acta Anaesthesiologica Scandinavica (1997), 41(1 Pt 1), 25-34

BACKGROUND: Liposomes containing local anaesthetics have been administered intrathecally and in the epidural space. Poor attention has been given to the pharmacokinetics of liposomes as drug carriers ... [more ▼]

BACKGROUND: Liposomes containing local anaesthetics have been administered intrathecally and in the epidural space. Poor attention has been given to the pharmacokinetics of liposomes as drug carriers. Therefore, we observed the biodistribution of liposomes after intrathecal injection in rats by scintigraphic imaging during 24 h. METHODS: We administered 99mTc-labeled multilamellar (MLV) and small unilamellar vesicles (SUV) of defined size and volume dispersities into the cerebrospinal fluid at the lumbar level. Those vesicles were free of contamination by radiolabeled colloids as visualized by light and electron microscopy and of neurotoxic products from phosphatidylcholine hydrolysis and peroxidation, both during the preparation process and after 24 h incubation in cerebrospinal fluid at 37 degrees C in vitro. RESULTS: SUV immediately diffused from the lumbar site of injection to the head and were cleared between 1 and 24 h after injection. MLV were cleared more slowly from the spinal space and appeared in the head region 1 h after injection where they accumulated up to 24 h. These differences were explained in terms of vesicle sizes and volumes. SUV with 0.05 micron diameters were rapidly absorbed into the blood through the arachnoid granulations. In contrast, particles larger than the upper size limit of the arachnoid granulations permeability (+/- 8 microns) could accumulate in the head with a slow elimination rate. CONCLUSION: This difference in clearance from the intrathecal space outlines the importance of defining the size of the liposomes, the distribution of a tracer or a drug inside the liposomal preparation, the chemical stability and the absence of toxic degradation products of liposome formulations before clinical use. [less ▲]

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See detailNucleon nucleon interaction in a chiral constituent quark model
Stancu, Floarea ULg; Pepin, S.; Glozman, L Ya

in Physical Review. C : Nuclear Physics (1997), C56

We study the short-range nucleon-nucleon interaction in a chiral constituent quark model by diagonalizing a Hamiltonian comprising a linear confinement and a Goldstone boson exchange interaction between ... [more ▼]

We study the short-range nucleon-nucleon interaction in a chiral constituent quark model by diagonalizing a Hamiltonian comprising a linear confinement and a Goldstone boson exchange interaction between quarks. The six-quark harmonic oscillator basis contains up to two excitation quanta. We show that the highly dominant configuration is $\mid s^4p^2[42]_O [51]_{FS}>$ due to its specific flavour-spin symmetry. Using the Born-Oppenheimer approximation we find a strong effective repulsion at zero separation between nucleons in both $^3S_1$ and $^1S_0$ channels. The symmetry structure of the highly dominant configuration implies the existence of a node in the S-wave relative motion wave function at short distances. The amplitude of the oscillation of the wave function at short range will be however strongly suppressed. We discuss the mechanism leading to the effective short-range repulsion within the chiral constituent quark model as compared to that related with the one-gluon exchange interaction. [less ▲]

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See detailLes protéases stromales dans la progression cancéreuse mammaire
Foidart, Jean-Michel ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1997), 152(5), 229-35235-7

Matrix metalloproteases represent a family of proteases secreted as latent inactive enzymes able to degrade the majority of extracellular matrix components. These enzymes are overexpressed during several ... [more ▼]

Matrix metalloproteases represent a family of proteases secreted as latent inactive enzymes able to degrade the majority of extracellular matrix components. These enzymes are overexpressed during several pathological tissue remodelings including tumor progression and tumor invasion. It was indeed classically admitted that matrix metalloproteases involved in tumoral progression were preferentially expressed by cancerous cells. Our studies on gelatinase A and stromelysin-3 have, however, demonstrated that their messenger RNAS are detected in fibroblasts of the peritumoral stroma in human mammary carcinoma and not in the cancerous cells themselves. By immunohistochemistry, we have detected gelatinase A in the cytoplasm of fibroblasts and at the surface of the tumor cells. This membrane localization of the protein could result from its binding, following secretion by the neighbouring stromal cells, to a specific binding site expressed at the surface of the carcinoma cells. These cells are indeed able to induce an increased proteolytic activity by enhancing the transcription of these enzymes by peritumoral fibroblasts. These enzymes represent therefore potential targets for the development of new therapeutic strategies. [less ▲]

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See detailLat. collatrare
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (1997), 56

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See detailTwo Members Of The Human Mageb Gene Family Located In Xp21.3 Are Expressed In Tumors Of Various Histological Origins
Lurquin, C.; De Smet, C.; Brasseur, F. et al

in Genomics (1997), 46(3), 397-408

Genes of the MAGE family direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. Twelve closely related MAGE genes are located in the Xq28 region ... [more ▼]

Genes of the MAGE family direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. Twelve closely related MAGE genes are located in the Xq28 region. These genes share 60-98% nucleotide identity in their coding region. The presence of homologous genes in a region of Xp21.3 has been reported previously. We obtained the complete sequence of a 42-kb stretch of this region. It contains four MAGE-related genes, which we propose to name MAGE-B1, B2, B3, and B4 (HGMW-approved symbols MAGEB1, MAGEB2, MAGEB3, and MAGEB4). The coding regions of these genes share 66-81% nucleotide identity and show 45-63% identity with those of the MAGE genes located in Xq28. Like the MAGE genes located in Xq28, the MAGE-B genes are silent in normal tissues with the exception of testis. Like MAGE-1, 2, 3, 4, 6 and 12 (HGMW-approved symbols MAGEA1, 2, 3, 4, 6, and 12), genes MAGE-B1 and MAGE-B2 are expressed in a significant fraction of tumors of various histological types. The transcription of MAGE-B1 and MAGE-B2 can be induced by 5-aza-2'-deoxycytidine, suggesting that the activation of these genes in tumors results from a demethylation process. [less ▲]

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See detailThe Nucleotide Sequence Of Saccharomyces Cerevisiae Chromosome Vii
Tettelin, H.; Carbone, Mla.; Albermann, K. et al

in Nature (1997), 387(6632),

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See detailLes antidotes en Médecine Vétérinaire
Delaunois, A.; Plume, Ch; Ansay, M. et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailFrom an architectural sketch to its semantic representation
Leclercq, Pierre ULg

in International Journal of Construction Information Technology (1997), 4(2), 67-84

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See detailRoom temperature fluorescence spectra of protochlorophyllide and chlorophyllide forms in etiolated bean leaves
Boddi, B.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (1997), 41(1-2), 73-82

Room-temperature fluorescence emission and excitation spectra of 3-day or 10-day old dark-grown bean (Phaseolus vulgaris L. cv Commodore) leaves were measured. The excitation light was defocused in such ... [more ▼]

Room-temperature fluorescence emission and excitation spectra of 3-day or 10-day old dark-grown bean (Phaseolus vulgaris L. cv Commodore) leaves were measured. The excitation light was defocused in such way that only a low rate of phototransformation took place and protochlorophyllide (Pchlide) forms could be detected. The spectra were resolved into gaussian components using a new method based on the comparison of the 4th derivative of the experimental spectrum and that of the calculated spectrum, i.e. the sum of the gaussians. In addition to Pchlide emission bands with maxima at 631, 644, 655 and 667 nm which correspond to those described earlier in 77 K spectra, two new and unusally narrow bands were found at 637 and 650 nm. Tn the Chlide region, emission bands were found at 676, 682, 686 and 695 nm. Changes in the relative amplitudes of the Pchlide and Chlide room temperature emission bands as a function of age, of excitation wavelength and in response to a short light flash were studied. A model is given in which dynamic interconversions of the pigment forms are suggested and the presence of the new forms is explained with the differences in the aggregational states of the pigments and with their interaction with NADPH or NADP(+). (C) 1997 Elsevier Science S.A. [less ▲]

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See detailThe intensity of emotional facial expression and decoding accuracy
Hess, U; Blairy, Sylvie ULg; Kleck, R

in Journal of Nonverbal Behavior (1997), 21

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See detailLes jeunes, leur activité physique et leurs perceptions de la santé, de la forme, des capacités athlétiques et de l’apparence
Ledent, Maryse; Cloes, Marc ULg; Piéron, Maurice

in Sport (1997), 159/160

La perception de sa propre compétence exerce un rôle primordial dans la décision de pratiquer une activité physique. La continuité d'une pratique résulte notamment d'un niveau de compétence jugé suffisant ... [more ▼]

La perception de sa propre compétence exerce un rôle primordial dans la décision de pratiquer une activité physique. La continuité d'une pratique résulte notamment d'un niveau de compétence jugé suffisant. A partir de 12 ans, les jeunes sont capables d'évaluer leur compétence et de faire la distinction entre cette dernière et l'effort déployé dans la performance réalisée. ... [less ▲]

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See detailStudies on the O-J-I-P transient of chlorophyll fluorescence in relation to photosystem II assembly and heterogeneity in plastids of greening barley
Barthelemy, X.; Popovic, R.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (1997), 39(3), 213-218

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of ... [more ▼]

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of etiolated leaves of Hordeum vulgare. The initial photochemical phase (O-J) due to reduction of the primary quinone acceptor Q(A) was found to represent a constant proportion (65-70%) of total variable fluorescence independent of greening time. The partial fluorescence quenching in the Q(A)-reduced state seems, therefore, to represent a basic property of PSII electron transport. The biphasic character of the slower J-I-P transient due to reduction of the plastoquinone pool developed progressively during the first hours of greening. in the same period of lime the proportion and rate constant of rapid PSII alpha sub-population increased, as calculated from the induction curve in the presence of DCMU. Etiochloroplasts or chloroplasts resuspended in low salt medium showed a low I level, which was restored upon readdition of 5 mM MgCl2 and NaCl. Salts also increased the apparent proportion of PSII alpha. These results suggest that the J-I and I-P phases of the induction curve are related to different rates of plastoquinone photoreduction by two distinct PSII populations. The effects of DMQ and of DCBQ on the O-J-I-P transient were also studied in (etio-)chloroplasts, In addition to the already reported quenching of the initial (F-0) and variable fluorescence by DCBQ, a slow fluorescence increase phase was found to appear upon the addition of DCBQ but not of DMQ. The latter observations confirm that DCBQ differs from DMQ by its higher efficiency as PSII electron acceptor. (C) 1997 Elsevier Science S.A. [less ▲]

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See detailIdentification des vaches laitières traitées à la somatotropine bovine
Scippo, Marie-Louise ULg; Degand, Guy ULg; Duyckaerts, Anne et al

in Annales de Médecine Vétérinaire (1997), 141(5), 381-390

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See detailStudy on the Production of Xylanolytic complex from Pencillium canescens 10-10c.
Gaspar, A.; Cosson, T.; Roques, C. et al

in Applied Biochemistry and Biotechnology (1997), 67

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See detailTheoretical study of slope effects in resistivity surveys and applications
Sahbi, Hassan; Jongmans, Denis; Charlier, Robert ULg

in Geophysical Prospecting (1997), 45(5), 795-808

When electric soundings are made over an irregular terrain, topographic effects can influence the values of apparent resistivity and lead to erroneous 1D interpretation. A 3D finite-element method has ... [more ▼]

When electric soundings are made over an irregular terrain, topographic effects can influence the values of apparent resistivity and lead to erroneous 1D interpretation. A 3D finite-element method has been applied to study the topographical effect of a slope on Schlumberger soundings parallel to the strike. When the resistivity survey is performed at the top of the slope, the apparent resistivity values can be two times higher than in the flat-earth case, depending on the angle (alpha) and height (H) of the slope, and on the distance (X) between the sounding and the slope top. The results are presented as nondimensional curves which can be used for evaluating topographic anomalies for any value of the parameters alpha, H and X. It is numerically shown that the topographic effects can be removed from measurements on horizontally layered structures with an irregular earth surface. Real measurements were performed in different geological conditions over an irregular terrain. The correction method based on the nondimensional curves has been applied to the data and has enabled the determination of the correct layered ground configuration using 1D interpretation. [less ▲]

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See detailEnergy savings in methanol synthesis: Use of heat integration techniques and simulation tools.
Maréchal, François; Heyen, Georges ULg; Kalitventzeff, Boris ULg

in Computers & Chemical Engineering (1997), 21(Suppl. S), 511-516

Starting with a classical process for producing methanol using the reforming and synthesis steps, a combined approach applying simulation models and a new synthesis strategy, named Effect Modelling and ... [more ▼]

Starting with a classical process for producing methanol using the reforming and synthesis steps, a combined approach applying simulation models and a new synthesis strategy, named Effect Modelling and Optimisation (EMO), has been used to optimise the energy efficiency of the process. The method allows to identify different ways of improving the energy efficiency of the process. The modifications concern the synthesis reactor and the reforming reactor designs, the exploitation of the purge stream as fuel gas to satisfy the process requirement and its integration to a gas turbine system. The EMO approach allows to target the impact of a process modification at the global level of the energy cost of the process, including the combined production of heat and mechanical power in a gas turbine and the steam network. Starting with a classical methane conversion of 60% for the classical system, we identify solutions with up to 93% of the overall methane conversion when we transform the net mechanical power produced into methane savings at the country level. The interest of the approach is the possibility of computing the impact of the process modifications suggested by the analysis of the shape of the heat cascade on the overall energy balance of the plant without having to simulate in many details the steam and the heat exchanger network. [less ▲]

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See detailThe yeast genome directory.
Goffeau, A.; Hilger, F.; Portetelle, Daniel ULg et al

in Nature (1997), 387(5),

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See detailA novel virus blinding assay using confocal microscopy: demonstration that the intracellular and extracellular vaccinia virions bind to different cellular receptors
Vanderplasschen, Alain ULg; Smith, G. L.

in Journal of Virology (1997), 71

Vaccinia virus (VV) produces two antigenically and structurally distinct infectious virions, intracellular mature virus (IMV) and extracellular enveloped virus (EEV), which bind to unidentified and ... [more ▼]

Vaccinia virus (VV) produces two antigenically and structurally distinct infectious virions, intracellular mature virus (IMV) and extracellular enveloped virus (EEV), which bind to unidentified and possibly different cellular receptors. Studies of VV binding have been hampered by having two infectious virions and by the rupture of the EEV outer membrane in the majority of EEV virions during purification. To overcome these problems, we have developed a novel approach to study VV binding that is based on confocal microscopy and does not require EEV purification. In this assay, individual virus particles adsorbed to the cell are simultaneously distinguished and quantified by double immunofluorescence labelling with antibody markers for EEV and IMV. By this method, we show unequivocally that IMV and EEV bind to different cellular receptors. Three independent observations allow this conclusion. First, the efficiencies with which IMV and EEV bind to different cell lines are unrelated; second, cell surface digestion with some enzymes affects IMV and EEV binding differently; and third, the binding of a monoclonal antibody to cells prevents IMV binding but not EEV binding. This technique may be widely applicable for studying the binding of different viruses. [less ▲]

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See detailRadiographical Assessment of Interphalangeal Rotation in the Evaluation of Equine Digital Conformation
Caudron, I.; Grulke, Sigrid ULg; Gabriel, Annick ULg et al

in Acta Anatomica (1997), 160(2), 95-9

This study is a part of a work to design a radiographical method to objectively define the conformation of an equine digit and to assess the individual appropriate trimming of a horse. Various angles were ... [more ▼]

This study is a part of a work to design a radiographical method to objectively define the conformation of an equine digit and to assess the individual appropriate trimming of a horse. Various angles were measured directly from the phalangeal bones. The authors observed that the bone relief of the sesamoid ligament insertions on the proximal phalanx was an essential landmark to determine the phalangeal alignment. The same angles were measured from specific radiographs and made it possible to quantify the rotation imposed to the proximal phalanx. The authors also noticed that the phalangeal rotation had little influence on the radiographic image of articular asymmetry. [less ▲]

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See detailApprentissage implicite et temps de réaction sériel: Une perspective développementale
Meulemans, Thierry ULg; Van der Linden, Martial ULg; Perruchet, Pierre

in Neuropsychiatrie de l'Enfance et de l'Adolescence (1997), 45(7-8), 384-386

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See detailA 5,6-Dihydro-Isopyoverdin From Azomonas Macrocytogenes
Michalke, R.; Taraz, K.; Budzikiewicz, H. et al

in Zeitschrift Fur Naturforschung C-A Journal of Biosciences (1997), 52(11-12),

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See detailSynthesis and characterization of porous silica-alumina xerogels
VanCantfort, Olivier; Abid, A.; Michaux, Bernard et al

in Journal of Sol-Gel Science and Technology (1997), 8

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See detailEtudes phénoménologiques
Ryle, Gilbert; Leclercq, Bruno ULg

in Recherches Husserliennes (1997), 7

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See detailGlucose metabolism during bovine preimplantation development: analysis of gene expression in single oocytes and embryos.
Lequarré, Anne-Sophie ULg; Grisart, B.; Schuurbiers, N. et al

in Molecular Reproduction and Development (1997), 48(2), 216-26

Glucose metabolism of the bovine embryo is low during the first cleavages and increases sharply after the major resumption of the genome (8-16 cells). The mRNA level for genes involved in glucose ... [more ▼]

Glucose metabolism of the bovine embryo is low during the first cleavages and increases sharply after the major resumption of the genome (8-16 cells). The mRNA level for genes involved in glucose metabolism was tested by RT-PCR on individual oocytes and embryos at different stages of development. These genes were: glucose transport GLUT-1, hexokinase (HK), glucose-6-phosphatase-dehydrogenase (G6PDH), and glucose-phosphate-isomerase (GPI); actin was used as a reference transcript. RT-PCR results revealed three types of oocytes or embryos: positive with a PCR signal for each transcript considered, nul with no signal for any transcript, and heterogeneous with a PCR signal for some transcripts and none for others. The number of nul and heterogeneous samples was higher for slow than for fast-cleaving embryos (81% vs. 36%), and the proportion of positive embryos increased significantly at the 16-cell and morula stages (P < 0.002), suggesting a correlation between mRNA content and developmental capacity. In positive embryos, GLUT-1 level was reduced by half during maturation and fertilization. Actin and hexokinase mRNA levels decreased during the first cleavages, but significantly increased at the 16-cell and morula stages, respectively. GPI transcript remained stable throughout development, whereas there was a significant rise for G6PDH at the 4-cell stage, perhaps due to a polyadenylation process. Finally, the absence or decrease in intensity of several transcripts at the blastocyst stage suggests suboptimal culture conditions. [less ▲]

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See detailVers une chirurgie mammaire supraconservatrice des lésions mammaires infracliniques?
LIFRANGE, Eric ULg; COLIN, Claude

in Gunaïkeia (1997), 2

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See detailRadiotherapie externe focalisee apres resection de metastase cerebrale unique: etude prospective de phase I-II
Zouhair; COUCKE, Philippe ULg; Douglas, Pelham et al

in Bulletin du Cancer. Radiothérapie : Journal de la Société Française du Cancer : Organe de la Société Française de Radiothérapie Oncologique (1997), 1

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See detailPotential of Varicella zoster virus thymidine kinase as a suicide gene in breast cancer cells
Grignet, Christine ULg; Calberg-Bacq, Claire-Michelle

in Gene Therapy (1997), 4

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See detailLong term follow-up of patients with acute myelogenous leukemia who received the daunorubicin, vincristine, and cytosine arabinoside regimen.
Beguin, Yves ULg; Sautois, Brieuc ULg; Forget, Patricia ULg et al

in Cancer (1997), 79(7), 1351-4

BACKGROUND: In 1985, the authors published a study of acute myelogenous leukemia (AML) patients treated with a chemotherapeutic regimen that was then considered intensive. Ten years later, the authors ... [more ▼]

BACKGROUND: In 1985, the authors published a study of acute myelogenous leukemia (AML) patients treated with a chemotherapeutic regimen that was then considered intensive. Ten years later, the authors reanalyzed the same cohort to determine whether the very promising actuarial results observed at 5 years held after longer follow-up. METHODS: Between 1977 and 1982, 61 patients with AML were treated with a protocol consisting of daunorubicin, vincristine, and cytosine arabinoside induction followed by consolidation and maintenance for a total of 2 years. The complete remission (CR) rate was 66%, 84% in males versus 47% in females (P < 0.005). At the time of the first analysis in 1984, the overall survival (OS) was 17%, the projected 5-year continuous CR rate (CCR) 32%, and the disease free survival (DFS) rate 29%, with the best results observed for males and for patients ages 40-60 years (P < 0.05). RESULTS: When the data were reanalyzed 11 years later in 1995, the results were 14% OS, 23% CCR, and 16% DFS at 5 years. However, these figures dropped to 8%, 18%, and 11% at 10 years and to 8%, 12%, and 7% at 15 years, respectively. Among the 40 CR patients, 31 relapsed (up to 13 years after CR), and all died within 1.6 years after relapse. Nine patients were in CCR: 4 died of unrelated causes (suicide, alcoholic cirrhosis, acute peritonitis, or bladder carcinoma), 1 was lost to follow-up after 11 years, 2 were alive and well at 17 years at last follow-up, and 2 were transplanted in first CR and were doing well at 13 and 14 years at last follow-up. The survival advantage for males over females persisted (P = 0.0197), but the advantage for patients age 40-60 years did not hold. CONCLUSIONS: These long term data indicate that actuarial analysis at 5 years may overestimate the cure rate of AML patients because a number of late relapses do occur. However, the picture is blurred by the incidence of death not related to leukemia or its treatment; and when these patients were censored at the time of death, 17% of CR patients were still projected to be alive and free of leukemia after 17 years. [less ▲]

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See detailChimie et immunologie: controle de qualite des eaux.
Portetelle, Daniel ULg; Copin, A.; Hecquet, J. F.

in Agricontact (1997), (290),

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See detailSpectroscopy of Ne IV in the wavelength Range 450–1100 Å
Bastin, Thierry ULg; Biémont, Emile ULg; Dumont, Paul-Dominique ULg et al

in Journal of the Optical Society of America. B, Optical Physics (1997), 14

An analysis of the Ne IV spectrum was undertaken in the 450–1100-Å spectral range. The spectra were produced by the beam–foil method with beam energies of 1.2 and 2.5 MeV, respectively. The resolution ... [more ▼]

An analysis of the Ne IV spectrum was undertaken in the 450–1100-Å spectral range. The spectra were produced by the beam–foil method with beam energies of 1.2 and 2.5 MeV, respectively. The resolution that was achieved, with a normal-incidence 2-m spectrometer, was sufficient to identify 53 new Ne IV lines and, consequently, to determine 18 new levels in the quartet and doublet systems and one sextet term. The energy values of 13 additional levels were also revised. The classification work was facilitated by the use of scaled relativistic Hartree–Fock calculations. [less ▲]

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See detailLa nature de l'acte juridique attesté par l'O. Mich. III 1098
Straus, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1997), LXXII(143), 128-129

O. Mich. III 1098 attests the delivery of a slave as a surety of a loan.

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See detailSurveys of ultraviolet-excess quasar candidates in large fields
Gosset, Eric ULg; Moreau, O.; Surdej, Jean ULg et al

in Astronomy and Astrophysics. Supplement Series (1997), 123

We describe the results of a survey for moderately bright quasars performed in a 20.6-square-degree field around the galaxy NGC 450. The quasar candidates were selected on the basis of their ultraviolet ... [more ▼]

We describe the results of a survey for moderately bright quasars performed in a 20.6-square-degree field around the galaxy NGC 450. The quasar candidates were selected on the basis of their ultraviolet excess: by comparative visual inspection of the double image of each single object on a U/B dual-exposure Schmidt photographic plate, 95 primary and 45 secondary quasar candidates were selected on the basis of their $U$ image being too bright. The spectroscopic identification of the primary candidates led to the discovery of 59 bona fide quasars (out of which 6 were previously known). The Palomar Schmidt plate was digitised using the MAMA measuring machine and the outcoming data reduced using ad hoc procedures. A photometric calibration allowed us to derive values for the limiting magnitudes and for the U-B index selection threshold of the survey. A catalogue containing 60 quasars is presented with accurate positions, magnitudes and additional information such as redshifts. We studied the spatial distribution of the objects and detected, for the quasars of our sample, a significant deviation from randomness in the form of a propensity to cluster in pairs on the celestial sphere with a typical scale of about 10 arcmin. We also formally detected a tendency towards a 3-D clustering, but this result is induced by a single pair of quasars. A forthcoming paper will deal with a similar work performed in a field around NGC 520; the latter field is located directly to the North of the present one and slightly overlaps it. Based on observations acquired at the Mount Palomar and Las Campanas Observatories as well as at the European Southern Observatory. Also based on Schmidt-plate digitisations performed with the MAMA measuring machine of C.A.I. (I.N.S.U., Paris). [less ▲]

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See detailThe glucocorticoid receptor inhibits the human prolactin gene expression by interference with Pit-1 activity
Nalda, Asunción M; Martial, Joseph ULg; Muller, Marc ULg

in Molecular & Cellular Endocrinology (1997), 134(2), 129-37

Glucocorticoids have been shown to inhibit the activity of the human prolactin (hPRL) promoter. Using transient expression experiments in rat pituitary cells, we located the sequence conferring ... [more ▼]

Glucocorticoids have been shown to inhibit the activity of the human prolactin (hPRL) promoter. Using transient expression experiments in rat pituitary cells, we located the sequence conferring glucocorticoid inhibition to a region which contains Pit-1 binding sites, responsible for pituitary-specific expression, but does not seem to contain a glucocorticoid receptor (GR) binding site. Co-transfection experiments in non-pituitary cell lines, using expression vectors for Pit-1 and different mutants of the human GR show that inhibition of the hPRL gene is seen only in the presence of Pit-1 and GR, and that the DNA binding function of the receptor is not required. Immunoprecipitation studies show that either anti-GR or anti-Pit-1 antibodies are able to co-precipitate GR and Pit-1, suggesting an interaction between these factors. We conclude that the activated GR functionally interferes with the pituitary specific factor Pit-1, thereby leading to the observed transcriptional repression. [less ▲]

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See detailLa localisation des productions agricoles : introduction méthodologique.
Merenne-Schoumaker, Bernadette ULg

in Bulletin de la Société Géographique de Liège (1997), (33), 129-138

First of all, the article specifies the links between agriculture and geography by emphasising both the speculiarities of the agricultural sector and the evolution of the problems concerning the ... [more ▼]

First of all, the article specifies the links between agriculture and geography by emphasising both the speculiarities of the agricultural sector and the evolution of the problems concerning the geographical researches dealing with the agricultural sector. Then, it defines the two main investigation areas of the agricultural geography : the analysis of the production distribution / sharing-out and the researches upon the factors and models of localisation. The two cases show how the authors endeavour to get devices that provide them a better understanding of the ever increasing complexity of the agricultural world. [less ▲]

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See detailThe faint young sun climatic paradox: Influence of the continental configuration and of the seasonal cycle on the climatic stability
Longdoz, Bernard; François, Louis ULg

in Global and Planetary Change (1997), 14(3-4), 97-112

A quasi-three-dimensional climate model is used to study the early state of the Earth when the solar luminosity was 70% of the present value, Usually, climatic simulations going back to this period lead ... [more ▼]

A quasi-three-dimensional climate model is used to study the early state of the Earth when the solar luminosity was 70% of the present value, Usually, climatic simulations going back to this period lead to a completely frozen planet contrasting with the geologic evidences of sedimentary rock formation and thus of the presence of liquid water at the surface of the continents during the Archean (4.6-2.5 billion years before present). Here, several model simulations are performed for solar luminosities varying between 0.7 and 1 times the present value. Using the present-day continental configuration and taking the seasonal cycle into account, a steady state is found in which glaciation is complete but snow covers only some oceanic coasts, leaving the continents essentially snow-free. As a result, the albedo of the continental area is strongly reduced compared to that of the frozen ocean, Some continental temperatures can almost reach the freezing point of water in summer (-1 degrees C in the center of Eurasia). This result can be explained by the behavior of the detailed hydrologic cycle included in the model. During the decrease of the solar luminosity, the jump to a completely frozen Earth occurs when the solar luminosity reaches 0.86 times its present value. The behavior of the climatic system is substantially different with a global ocean configuration. In the absence of land surfaces, the meridional heat transport, explicitly calculated, is less effective and the glaciation of a model latitude zone does not lead to the glaciation of its equatorward neighbor. The climate instability is relatively local and the jump to the completely frozen state is much more progressive than in the case of the modem continental configuration. The role of the seasonal cycle in the paleoclimatic simulation is also studied. Due to the non-linearity of the model, removing the seasonal cycle drives the system to an increase of the annual mean planetary albedo and to a decrease of the relative value (0.82) of the critical solar luminosity at which the jump to the completely frozen solution occurs. [less ▲]

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See detailReversibility of thiamine deficiency-induced partial necrosis and mitochondrial uncoupling by addition of thiamine to neuroblastoma cell suspensions.
Bettendorff, Lucien ULg; Goessens, Guy ULg; Sluse, Francis ULg

in Molecular and Cellular Biochemistry (1997), 174(1-2), 121-4

Culture of neuroblastoma cells in the presence of low thiamine concentration (16 nM) and of the transport inhibitor amprolium leads to the appearance of signs of necrosis: the chromatin condenses, the ... [more ▼]

Culture of neuroblastoma cells in the presence of low thiamine concentration (16 nM) and of the transport inhibitor amprolium leads to the appearance of signs of necrosis: the chromatin condenses, the oxygen consumption decreases and is uncoupled, the mitochondrial cristae are disorganized, the thiamine diphosphate-dependent dehydrogenase activities are impaired. When 10 microM thiamine are added to these cells, the basal respiration increases, the coupled respiration is restored and mitochondrial morphology is recovered within 1 h. Addition of succinate, which is oxidized via a thiamine diphosphate-independent dehydrogenase, to digitonin-permeabilized cells immediately restores a coupled respiration. Our results suggest that the slowing of the citric acid cycle is the cause of the biochemical lesion induced by severe thiamine deficiency and that part of the mitochondria remain functional. [less ▲]

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See detailInterobserver agreement on MNA nutritional scale of hospitalized elderly patients
Gazzotti, C.; Pepinster, A.; Petermans, Jean ULg et al

in Journal of Nutrition, Health & Aging (The) (1997), 1

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See detailNote on the measurement of the thermal conductivity and the double peak structure in high-Tc superconductors
Bougrine, Hassan ULg; Pekala, M.

in Superconductor Science & Technology (1997), 10(8), 621-623

We show that low-temperature measurements of the thermal conductivity of high-T-c superconductors can sometimes reveal a double peak structure depending on the experimental set-up used.

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See detailThe lowest 5g-6h supermultiplet of Fe II
Biémont, Emile ULg; Johansson, S.; Palmeri, P.

in Physica Scripta (1997), 55

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See detailRésumé des communications et livret guide des excursions
Petit, François ULg; Wastiaux, Cécile; Assani, Ali Arkamose et al

in Journées hydrologiques françaises (Commission des Hydrosystèmes fluviaux) Journées de terrain organisées en Ardenne et dans les Hautes fagnes (1997)

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See detailLesions observed on stranded seabirds along the Belgian coast from 1992 to 1995
Jauniaux, Thierry ULg; Brosens, L.; Coignoul, Freddy ULg

in ICES Journal of Marine Science (1997), 54(4), 714-717

From 1992 to 1995, dead seabirds found on Belgian beaches were collected and various tissues of 241 birds were sampled for histopathological, bacteriological, parasitological, and toxicological ... [more ▼]

From 1992 to 1995, dead seabirds found on Belgian beaches were collected and various tissues of 241 birds were sampled for histopathological, bacteriological, parasitological, and toxicological investigations. The most common species examined was the guillemot (Uria aalge). Necropsies revealed cachexia (severe emaciation), acute haemorrhagic gastro-enteropathy and oil contamination in many of these birds. Statistical analyses were performed in order to explore correlations of these with biological parameters such as age, sex, and origin (pelagic or non-pelagic). The pelagic origin of seabirds were associated with the three main findings. Oil contamination was associated with acute gastro-enteropathy and cachexia, and cachexia was more prevalent among juveniles. Finally, cachexia and acute gastro-enteropathy were strongly associated. It is possible that oiled pelagic seabirds become cachectic and die of acute gastro-enteropathy. (C) 1997 International Council for the Exploration of the Sea. [less ▲]

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See detailBovine Herpesvirus 1-Induced Apoptosis Occurs At The G0/G1 Phase Of The Cell Cycle
Hanon, Emilien ULg; Hoornaert, S.; Dequiedt, Franck ULg et al

in Virology (1997), 232(2), 351-358

We have previously shown that bovine herpesvirus 1 (BHV-1), even when inactivated, induces apoptotic cell death in mitogen-stimulated bovine peripheral blood mononuclear cells (PBMCs) (Hanon et al., 1996 ... [more ▼]

We have previously shown that bovine herpesvirus 1 (BHV-1), even when inactivated, induces apoptotic cell death in mitogen-stimulated bovine peripheral blood mononuclear cells (PBMCs) (Hanon et al., 1996, J. Virol. 70, 4116-4120). In order to gain insight into this process, we have investigated the cell cycle phase at which BHV-1 induces apoptosis in PBMCs. Our results show that the percentage of cells that progress through the S phase was always lower in BHV-1-infected PBMCs than in control cells. This effect was not due to a defective activation of mitogen-stimulated PBMCs since BHV-1 only slightly affected the percentage of cells expressing BoCD25, a well-known lymphocyte activation marker. Furthermore, mimosine and cyclosporine A, two chemicals that inhibit entry into the S phase of the cell cycle by different pathways, did not affect the ability of BHV-1 to induce apoptosis. BHV-1-induced apoptosis also occurred in unstimulated PBMCs and interestingly, this was associated with the expression of c-myc and BoCD25 proteins both of which are related to cell cycle progression. All together, these data provide evidence demonstrating that BHV-1-induced apoptosis occurs at the G0/G1 phase of the cell cycle. [less ▲]

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See detailFatty acid hydroperoxides pathway in plants. A review
Fauconnier, Marie-Laure ULg; Marlier, M.

in Grasas y Aceites (1997), 48(1), 30-37

The present paper focusses on the fatty acid hydroperoxides pathways, mainly hydroperoxide lyase and hydroperoxide dehydrase. For each enzyme, the definition, occurrence and subcellular localization is ... [more ▼]

The present paper focusses on the fatty acid hydroperoxides pathways, mainly hydroperoxide lyase and hydroperoxide dehydrase. For each enzyme, the definition, occurrence and subcellular localization is presented. Particular attention is given to reaction mecanisms and to substrate specificity. Physiological roles of reaction products are also discussed. [less ▲]

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See detaill'application des dispositions pénales générales en matière bancaire et boursière
Flore, Daniel ULg

in Revue de Droit Commercial Belge [= RDC] = Tijdschrift voor Belgisch Handelsrecht [=TBH] (1997), 4

L'objectif est de dresser un cadre pénal général pour l'approche du droit pénal bancaire et boursier.

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See detailProductivity and Convergence in OECD Service Industries
Gouyette, Claudine; Perelman, Sergio ULg

in Structural Change and Economic Dynamics (1997), 8

The objective of this paper is threefold. First, to estimate the productivity performances realized in service and manufacturing industries by 13 OECD countries over the period 1970-1987. Secondly, to ... [more ▼]

The objective of this paper is threefold. First, to estimate the productivity performances realized in service and manufacturing industries by 13 OECD countries over the period 1970-1987. Secondly, to compare the productivity indicators computed under the alternative frontier analysis and Divisia index approaches. Thirdly, to test the convergence phenomenon in both industries, focusing on the catching-up process and on the interaction between productivity changes and capital intensity variations. The main results show that, contrary to the manufacturing sector and in spite of very low growth rates, productivity levels converge in services. Moreover, new investments in capital appear to exert an unexpected depressive effect on total factor productivity growth in service activities, while having a positive influence in manufacturing industries. [less ▲]

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See detailSchool Geography Textbooks in Francophone Belgium
Merenne-Schoumaker, Bernadette ULg

in International Research in Geographical & Environmental Education (1997), 6(1), 86-88

Review on the situation of geographical textbooks in Belgium since the French education reform in 1969

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See detailClostridium perfringens urease genes are plasmid-borne.
Dupuy, B.; Daube, Georges ULg; Popoff, M. R. et al

in Infection and Immunity (1997), 65

Although many bacteria are ureolytic, and in some cases urease acts as a virulence factor, the urease phenotype has not been analyzed in the anaerobic pathogen Clostridium perfringens. In this study, ;2 ... [more ▼]

Although many bacteria are ureolytic, and in some cases urease acts as a virulence factor, the urease phenotype has not been analyzed in the anaerobic pathogen Clostridium perfringens. In this study, ;2% of C. perfringens strains, representing the principal biotypes, were found to harbor the urease structural genes, ureABC, and these were localized on large plasmids that often encode, in addition, the lethal « or i toxins or the enterotoxin. This represents the first report of a plasmid-encoded urease in a gram-positive bacterium. The C. perfringens enzyme was highly similar to the ureases of other bacteria and cross-reacted with antibodies raised against the urease purified from Helicobacter pylori. Urease production was inhibited by urea and induced under growth conditions where the availability of nitrogen sources was limiting. To date, this form of regulation has been observed only for chromosomal ureABC genes. [less ▲]

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See detailMultiple pregnancy-associated glycoproteins are secreted by day 100 sheep placenta
Xie, Sancai; Green, Jonathan; Bao, Bagna et al

in Biology of Reproduction (1997), 57(6), 1384-1393

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep ... [more ▼]

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep and other ruminants produce similar products. There is evidence, however, that these antigens, which are related structurally to the pepsinogens and other aspartic proteinases, are not single gene products but members of an extensive family. Here, the sequential use of ammonium sulfate precipitation and Sepharose blue, anion-exchange, and cation-exchange chromatographies, as well as isoelectric elution from a Mono P column, has allowed several PAG1-related molecules to be purified from the medium after culture of explants from Day 100 sheep placentas. Each of these PAGs cross-reacted to a varying extent with a panel of three different anti-PAG1 antisera. Four of them, all of which were major secretory products of the placenta, were subjected to amino-terminal microsequencing. Although each was related to ovine (ov) PAG1, none was identical. Reverse transcription-polymerase chain reaction was then used to amplify PAG1-related cDNA from Day 100 placental RNA. Seven novel full-length cDNA, all distinct from ovPAG1, were identified from 25 cDNA selected for sequencing. Only two of these (ovPAG3 and ovPAG7) encoded polypeptides identical in sequence at their inferred amino termini to one of the PAGs (ovPAG65) purified from explant cultures. Even so, they were only 84% identical in overall sequence. The remaining five cDNA were unique. In situ hybridization analysis revealed that expression of ovPAG3 and ovPAG7, like that of ovPAG1, is confined to trophoblast binucleate cells. The data confirm that at Day 100 of pregnancy the ovine placenta produces many different PAGs, which differ considerably in sequence and immunological cross-reactivity. [less ▲]

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See detailNotes of the flea fauna (Insecta, Siphonaptera) of the terrestrial azorean mammals
Libois, Roland ULg; Fons, Roger; Mathias, Maria da Luz et al

in Arquivos do Museu Bocage. Nova série (1997), 3(1), 1-11

During three successive years, field samplings of wild mammals were organised on different Azorean islands and the ectoparastes were collected. Among 340 murid rodents, 31 did bear at least one flea ... [more ▼]

During three successive years, field samplings of wild mammals were organised on different Azorean islands and the ectoparastes were collected. Among 340 murid rodents, 31 did bear at least one flea. Nosopsyllus l. londiniensis has been found on the mouse in São Miguel. Stenoponia t. tripectinata has been discovered in Terceira and in São Miguel, mainly on house mice and on one black rat out of 121. Nosopsyllus fasciatus was present on the mouse and on both the black and the Norway rats. Its presence has been evidenced in four islands: São Miguel, Terceira, Graciosa and Flores. Numerous rabbits were also examined in the visited islands (São Miguel, Terceira, Pico, São Jorge, Faial and Flores) and were found heavily parasited by their commonest flea, Spilopsyllus cuniculi. In Flores, however, that flea seems to be lacking. Though no systematic search has been done on domestic animals, the presence of Ctenocephalides f. felis is also reported from Flores, Terceira and Graciosa whereas C. canis has been found on a dog in Florès. The flea fauna of the Azorean archipelago is therefore characterized by a few species amongst the most cosmopolitan ones [less ▲]

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See detailLe diagnostic de la reproduction: fertilité, gestation, anœstrus
Delahaut, Philippe; Sulon, Joseph ULg; Ectors, Francis et al

in Cahiers Agricultures (1997), 6

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See detailDetermination rapide par immunodosage de l'hemoglobine glyquee sur sang capillaire comparee a une methode d'affinite pour le boronate et capture d'ions sur sang veineux.
Bozet, Marie-Claire ULg; Gerard, Pascale ULg; Scheen, André ULg et al

in Annales de Biologie Clinique (1997), 55(2), 139-44

Measurement of glycosylated haemoglobin has become an essential tool in the management of diabetic patients. A recently developed device allows the rapid immuno-assay of HbA1c in 1 microliter capillary ... [more ▼]

Measurement of glycosylated haemoglobin has become an essential tool in the management of diabetic patients. A recently developed device allows the rapid immuno-assay of HbA1c in 1 microliter capillary blood obtained by a finger prick. In 100 ambulatory diabetic patients, we compared the results obtained with this method to those obtained in venous blood using a standard affinity chromatography laboratory method. Although both methods correlated (r = 0.88, p < 0.001), the mean +/- SD levels respectively obtained differed slightly (7.6 +/- 1.5 vs 79 +/- 1.4% p < 0.001). The 95% confidence interval of the difference was [-0.41. -0.14]. Considering a cut-off HbA1c value of 8%, as indicative of the need for treatment adjustment, 33 patients with the capillary blood immuno-assay method and 42 with the venous-blood affinity chromatography method were above that limit (Mc Nemar test, p < 0.05). In conclusion, the rapid assay of HbA1c in capillary blood can be useful for the management of some diabetic patients but the results are not readily exchangeable with those obtained from other standardized laboratory methods. Consequently, specific ranges and clinical decision limits must be determined. [less ▲]

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See detailDesign Of A New Class Of Amphipathic Helical Peptides For The Plasma Apolipoproteins That Promote Cellular Cholesterol Efflux But Do Not Activate Lcat
Labeur, C.; Lins, Laurence ULg; Vanloo, B. et al

in Arteriosclerosis, Thrombosis, and Vascular Biology (1997), 17(3), 580-8

Amphipathic helical peptides represent the lipid-binding units of the soluble plasma apolipoproteins. Several synthetic peptide analogues have been designed to mimic such structures and have been used to ... [more ▼]

Amphipathic helical peptides represent the lipid-binding units of the soluble plasma apolipoproteins. Several synthetic peptide analogues have been designed to mimic such structures and have been used to unravel some of the mechanisms involved in the physiological function of the apolipoproteins, including lipid binding, LCAT activation, and enhancement of cholesterol efflux from lipid-laden cells. A series of novel synthetic peptides, named ID peptides, was modeled on the basis of the structural properties common to the amphipathic helices of apolipoprotein (apo) A-I. In these new peptides, however, the segregation between hydrophobic and hydrophilic faces of the helices is more pronounced than in apoA-I, so that the surface of the hydrophobic and hydrophilic faces of the amphipathic helices is equal. Moreover, there are fewer negatively charged residues in the center of the hydrophilic face of the helical peptides. Most charged amino acids are located along the edge of the helix and are susceptible to forming salt bridges with residues of an antiparallel helix, such as around a discoidal phospholipid/peptide complex. The physicochemical characteristics of these peptides and their complexes with phospholipids were compared with those of the 18A peptide and its lipid/peptide complex. All ID peptides bind dimyristoylphosphatidylcholine vesicles more rapidly than the 18A peptide to yield discoidal peptide/phospholipid complexes of comparable size. The alpha-helical content of the lipid-free ID peptides is close to that of the 18A peptide and increases slightly on lipid binding. The stability of the ID and 18A peptides and of the phospholipid/peptide complexes against guanidinium hydrochloride denaturation is higher than that of lipid-free and lipid-bound apoA-I. LCAT activation by the 18A/phospholipid/cholesterol complexes equals that of apoA-I/ phospholipid/cholesterol complexes, whereas none of the ID peptides tested is able to activate LCAT to a significant extent. Incubation of the peptide/phospholipid complexes with lipid-laden macrophages induces cellular cholesterol efflux and incorporation of cholesterol into the complexes. The cholesterol efflux capacity of the peptide/phospholipid complexes is comparable among the peptides and higher than that of apoprotein/phospholipid complexes. In conclusion, although the amphipathicity of the new peptides is higher than that of the 18A model peptide, the lack of LCAT activation by the ID peptides suggests that an enhanced segregation of the hydrophobic and hydrophilic residues, equal magnitude of hydrophobic and hydrophilic faces of the helix, and the absence of negatively charged residues in the central part of the hydrophilic face might account for the lack of LCAT activity of these peptides. These parameters do not affect the capacity of the peptide/phospholipid complexes to promote cellular cholesterol efflux. [less ▲]

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See detailCell-line specific radiosensitizing effect of zalcitabine (DDC)
Coucke, Philippe ULg; Li, Ye-Xiong; Copaceanu, Marie-Laure et al

in Acta Oncologica (1997)

The potential of zalcitabine (ddC) to act as an ionizing radiation response modifier was tested on exponentially growing human cancer cells in vitro. Two human cell lines, WiDr (colon) and MCF-7 (breast ... [more ▼]

The potential of zalcitabine (ddC) to act as an ionizing radiation response modifier was tested on exponentially growing human cancer cells in vitro. Two human cell lines, WiDr (colon) and MCF-7 (breast) were exposed to ddC at 10 p M concentration for various lengths of tide (18, 24, 48 and 72 h). On the WiDr cell line the dual effect of concentration and duration of exposure prior to irradiation was investigated. Experimental endpoints were clonogenicity and viability, as measured by colony formation assay (CFA) and MTT assay respectively. The impact on cell-cycle distribution prior to irradiation was assessed by flow cytometry using a double labeling technique (propidium iodide and bromodeoxyuridine pulse label). A significant reduction in surviving fraction and viability was observed for WiDr-cells irradiated after pre-exposure to 10 pM for 18, 48 and 72 h as compared to corresponding irradiated controls. At lower concentrations (1 and 5 pM), the radiosensitizing effect was only significant after a 72-h exposure (assessed by CFA). For MCF-7, ddC induced a significant modification of the dose response only with 24 and 48 h preincubation. However, the overall effect was less pronounced as compared to WiDr. Cell-cycle analysis showed accumulation in S-phase, 48 and 72 h after treatment with 10 pM ddC in the WiDr cells, with a progressive shift to late S-phase as shown by the biparametric analysis. The degree of radiosensitization is cell-line dependent with the most important sensitization observed on the most <<radioresistant cell line>>, ix., the cell line with the lowest alpha value and highest SF 2 (WiDr). For WiDr, radiosensitization by ddC depends on the duration of exposure and the concentration of the drug. Received 29 February 1996 Accepted 10 December 1996 [less ▲]

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See detailAcetaldehyde-induced changes in the monoamine and amino acid extracellular microdialysate content of the nucleus accumbens
Ward, Roberta J.; Colantuoni, Carlo; Dahchour, Abdelkhader et al

in Neuropharmacology (1997), 36(2), 225-232

The effect of an acute intraperitoneal (i.p.) injection of acetaldehyde, 20 mglkg or 100mg/kg, on the microdialysate content of both amino acids and monoamine was studied in the nucleus accumbens (NA) by ... [more ▼]

The effect of an acute intraperitoneal (i.p.) injection of acetaldehyde, 20 mglkg or 100mg/kg, on the microdialysate content of both amino acids and monoamine was studied in the nucleus accumbens (NA) by a microdialysis technique. Acetaldehyde (ACH) which was detectable at levels of 50-130 µmol/g brain tissue 10 min after injection, evoked a significantd ecrease in the extracellular microdialysis dopamine content, which was sustained for the period of the study, i.e. 120 min. Homovanillicacid, HVA, decreased significantly when the lower dose of ACH was administered while dihydrophenylaceticacid, DOPAC, showed no significant change with either dose of ACH during the period of the study. Serotonin levels decreased significantly after both doses of acetaldehyde, with significant increases of its major metabolite, hydroxyindolacetic acid, 5-HIAA, with the higher acetaldehyde dose. Taurine increased significantly, only during the first twenty minutes, after both doses of acetaldehyde, although neither of the excitatory amino acids assayed, glutamate and aspartate, nor the inhibitoryamino acid, GABA, showed any significant changes. Acetaldehyde clearly evokes significant perturbation in the monoamine content of the NA, such changes being the converse to those reported for monoamine after ethanol administration, which might indicate a negative reinforcement effect. [less ▲]

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See detailProduction and activation of matrix metalloprotease-9 (MMP-9) by HL-60 promyelocytic leukemia cells
Devy, L.; Noël, Agnès ULg; Baramova, E. et al

in Biochemical and Biophysical Research Communications (1997), 238

Human promyelocytic HL-60 cells have been used as a model of acute leukemia to investigate the expression and the regulation of matrix metalloproteases (MMPs), known to contribute to the degradation of ... [more ▼]

Human promyelocytic HL-60 cells have been used as a model of acute leukemia to investigate the expression and the regulation of matrix metalloproteases (MMPs), known to contribute to the degradation of extracellular matrix components. As shown by gelatin zymography, HL-60 cells constitutively released significant amounts of proMMP-9 (92 kDa) and moderate amounts of proMMP-2 (72 kDa). Furthermore, casein zymography confirmed the presence of serine proteases in the form of pro-urokinase. Activation of proMMP-9 was dependent on the plasminogen activator/plasmin (PA/plasmin) system and was inhibited by aprotinin. MMP-9 was only detected in cellular extracts or conditioned media incubated with HL-60 cells, indicating that cells are essential to the activation process. Addition of plasminogen increased by 3-fold the basal invasive rate of these cells across a matrigel layer (2.1%versus0.7% in control cells after 4 h of incubation). Taken together, these results indicate that HL-60 cells exhibit an autocrine activation mechanism of proMMP-9 via the PA/plasmin system and that activation of proMMP-9 increases their invasive potential [less ▲]

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See detailSporopodiopsis, a new genus of lichens (Ectolechiaceae) from S-E Asia
Sérusiaux, Emmanuël ULg

in Abstracta Botanica (1997), 21

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See detailCirculation of the western Mediterranean: From global to regional scales
Beckers, Jean-Marie ULg; Brasseur, P.; Nihoul, Jacques ULg

in Deep-Sea Research Part II, Topical Studies in Oceanography (1997), 44(3-4), 531-549

A free-surface, three-dimensional, primitive equation model has been implemented with a horizontal resolution of 4.6 km to study the ocean circulation in the Gulf of Lions at time scales ranging from ... [more ▼]

A free-surface, three-dimensional, primitive equation model has been implemented with a horizontal resolution of 4.6 km to study the ocean circulation in the Gulf of Lions at time scales ranging from weeks to seasons. Numerical experiments have been conducted, in which the regional model is nested into a basin-scale model of the whole western Mediterranean. The global model is operated with a relatively coarse resolution (16 km) and provides boundary conditions at the open-sea boundaries of the regional domain. There is, however, no Feedback loop from the regional to the global model. The simulations are consistently driven with atmospheric fluxes computed from the output of the French PERIDOT meteorological forecasting system, between August 1988 and 1989. In addition to the initial conditions, in situ measurements of temperature and salinity are assimilated in the simulation of the general circulation, adopting a simple nudging technique to prevent an excessive drift of the model against climatology. The response of the regional model below and above the thermocline is discussed in the context of the prevailing meteorological situations. Some experiments give indications that a double-gyre system may develop from wind regimes that exhibit a cyclonic/anticyclonic wind stress curl. Advection-diffusion of passive tracers are also examined on the basis of the local hydrodynamic features, because this work has been conceived with the aim of determining the physical conditions in which ecological and biochemical processes develop at the interface between river mouths and the open ocean. (C) 1997 Elsevier Science Ltd. [less ▲]

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See detailElectron tomography of metaphase nucleolar organizer regions: evidence for a twisted-loop organization.
Heliot, L.; Kaplan, H.; Lucas, L. et al

in Molecular Biology of the Cell (1997), 8(11), 2199-216

Metaphase nucleolar organizer regions (NORs), one of four types of chromosome bands, are located on human acrocentric chromosomes. They contain r-chromatin, i.e., ribosomal genes complexed with proteins ... [more ▼]

Metaphase nucleolar organizer regions (NORs), one of four types of chromosome bands, are located on human acrocentric chromosomes. They contain r-chromatin, i.e., ribosomal genes complexed with proteins such as upstream binding factor and RNA polymerase I, which are argyrophilic NOR proteins. Immunocytochemical and cytochemical labelings of these proteins were used to reveal r-chromatin in situ and to investigate its spatial organization within NORs by confocal microscopy and by electron tomography. For each labeling, confocal microscopy revealed small and large double-spotted NORs and crescent-shaped NORs. Their internal three-dimensional (3D) organization was studied by using electron tomography on specifically silver-stained NORs. The 3D reconstructions allow us to conclude that the argyrophilic NOR proteins are grouped as a fiber of 60-80 nm in diameter that constitutes either one part of a turn or two or three turns of a helix within small and large double-spotted NORs, respectively. Within crescent-shaped NORs, virtual slices reveal that the fiber constitutes several longitudinally twisted loops, grouped as two helical 250- to 300-nm coils, each centered on a nonargyrophilic axis of condensed chromatin. We propose a model of the 3D organization of r-chromatin within elongated NORs, in which loops are twisted and bent to constitute one basic chromatid coil. [less ▲]

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See detailAerogel compression theoretical analysis
Pirard, René ULg; Pirard, Jean-Paul ULg

in Journal of Non-Crystalline Solids (1997), 212(2-3), 262-267

Several authors have empirically shown that, in aerogels, a power law exists between the mechanical moduli and the bulk density. An exponent value can be determined from mercury porosimetry curves. The ... [more ▼]

Several authors have empirically shown that, in aerogels, a power law exists between the mechanical moduli and the bulk density. An exponent value can be determined from mercury porosimetry curves. The shrinkage of aerogels under mercury pressure follows a buckling mechanism which links the pore size to the exerted pressure. The present study relates the exponent to the pore volume distribution which can be described by a hierarchical model valid in a large range of pore size, so a physical meaning is given to the exponent. [less ▲]

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See detailAnévrysme ou pseudoanévrysme ventriculaire?
Toussaint, A.C.; Waleffe, André ULg; Pierard, Luc ULg et al

in Revue Médicale de Liège (1997), 52(7), 457-62

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See detailThe Major Homology Region Of Bovine Leukaemia Virus P24(Gag) Is Required For Virus Infectivity In Vivo
Willems, Luc ULg; Kerkhofs, P.; Attenelle, L. et al

in Journal of General Virology (1997), 78

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See detailOn the Importance of Octupole Transitions in Atomic Spectra
Biémont, Emile ULg

in Physica Scripta (1997), T73

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See detailIUG-/ZOUG- dans une inscription latine écrite en lettres grecques (CIJ I 215)
Rochette, Bruno ULg

in Zeitschrift für Papyrologie und Epigraphik (1997), 115

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See detailSequence Analysis of the Bovine Herpesvirus Type 1 Genes Homologous to the DNA Polymerase (Ul30), the Major DNA-Binding Protein (Ul29) and Icp18.5 Assembly Protein (Ul28) Genes of Herpes Simplex Virus
Meyer, Gilles; Vlcek, C.; Paces, V. et al

in Archives of Virology (1997), 142(1), 89-102

The nucleotide sequence of a 10.5 kb region (map position 0.332 to 0.410) of bovine herpesvirus type 1 (BHV-1) was determined. This region contained three open reading frames (ORFs) homologous to herpes ... [more ▼]

The nucleotide sequence of a 10.5 kb region (map position 0.332 to 0.410) of bovine herpesvirus type 1 (BHV-1) was determined. This region contained three open reading frames (ORFs) homologous to herpes simplex virus DNA polymerase catalytic subunit (DNApol, UL30), major DNA-binding protein (MDBP, UL29) and ICP18.5 assembly protein (ICP18.5, UL28). The BHV-1 DNApol. MDBP and ICP18.5 ORFs were 1246, 1203 and 826 amino acids long with a calculated molecular mass of 134.2 kDa, 124.4 kDa and 86.9 kDa, respectively. They showed a high homology with alphaherpesvirus homologs despite large differences in the G + C content of the UL30-UL28 segment ranging from 44.4% for varicella zoster virus to 71.5% for BHV-1. Particularly well conserved among Alphaherpesvirinae are the putative functional domains of the DNApol and MDBP proteins which are discussed. Phylogenetic analysis revealed that BHV-1 clustered in the Varicellovirus genus with the animal D-type viruses. In this group, the BHV-1 position was shown to vary according to the investigated genes. Indeed, pseudorabies virus clustered with BHV-1 in the DNApol tree but with equine herpesvirus 1 in the ICP18.5 tree. [less ▲]

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See detailRéflexions sur l’iconologie de la châsse de saint Remacle
Van den Bossche, Benoît ULg

in Bulletin de la Société d’Art et d’Histoire du Diocèse de Liège (1997), LXII

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See detailPlasma leptin levels, insulin secretion, clearance and action on glucose metabolism in anorexia nervosa.
Letiexhe, Michel ULg; Scheen, André ULg; Lefebvre, Pierre ULg

in Eating and Weight Disorders [=EWD] (1997), 2(2), 79-86

From a metabolic point of view, anorexia nervosa may be viewed as a mirror image of obesity. We compared insulin secretion, clearance and action on glucose metabolism during an intravenous glucose ... [more ▼]

From a metabolic point of view, anorexia nervosa may be viewed as a mirror image of obesity. We compared insulin secretion, clearance and action on glucose metabolism during an intravenous glucose tolerance test in nine women with anorexia nervosa and in nine age-matched normal-weight controls. Insulin secretion (ISR) was derived by deconvolution of plasma C-peptide levels, insulin clearance (MCR(I)) was obtained by dividing the area under the curve (AUC(0-180 min)) of ISR by the corresponding AUC of plasma insulin levels, insulin sensitivity (S(I)) and glucose effectiveness index (S(G)) were calculated by Bergman's minimal model. The anorectic women had markedly lower BMI values (13.7+/-0.6 vs 23.2+/-0.8 kg/m2, p<0.0001) and serum basal leptin levels (2.8+/-0.6 vs 8.9+/-1.8 ng/mL, p=0.005) than control women. The anorectic women exhibited clear-cut lower fasting and post-glucose plasma insulin levels but similar corresponding plasma C-peptide concentrations when compared to controls. Consequently, ISR was similar in both groups while MCR(I) was significantly increased in anorexia nervosa (MCR(I): 3320+/-881 vs 822+/-79 mL x min(-1) x m(-2), p<0.02). The index S(I) tended to be higher in anorectic women than in normal-weight subjects, but without reaching the level of statistical significance because of a high between-subject variability (20.2+/-5.7 vs 12.5+/-2.2 10(-5) x min(-1)/pmol x L(-1), NS). The index S(G) was similar in both groups (0.022+/-0.004 vs 0.018+/-0.002 min(-1), NS). In conclusion, low plasma insulin levels observed in women with anorexia nervosa result from high MCR(I) rather than from depressed insulin secretion. Insulin sensitivity is not systematically increased and glucose effectiveness is unchanged in anorectic women when compared to normal-weight controls. [less ▲]

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See detailIncorporation of rapeseed meal extracted by pressure in a diet for growing fattening bulls .2. Glucosinolates and their breakdown products in the rumen
Wathelet, Jean-Paul ULg; Istasse, Louis ULg; Mayombo, A. P. et al

in Annales de Zootechnie (1997), 46(1), 71-79

Eight bulls from the Belgian Blue breed were offered diets in which soya bean meal and linseed meal were substituted by rapeseed meal (variety Samourai) in order to provide, respectively, 33, 66 and 100 ... [more ▼]

Eight bulls from the Belgian Blue breed were offered diets in which soya bean meal and linseed meal were substituted by rapeseed meal (variety Samourai) in order to provide, respectively, 33, 66 and 100% of the protein. The glucosinolate content was equal to 17.6 mu mol/g dry matter. Analyses of wet residues from rapeseed meal incubated in the rumen showed a rapid decrease of the glucosinolate content which disappeared after 5 h of incubation. The 3-hydroxypent-4-enenitrile, the but-3-enylisothiocyanate and the 5-vinyl-1,3-oxazolidine-2-thione antinutritional factors obtained from the glucosinolates were identified by GC-MS during the first 5 h. The 3-phenylpropanenitrile, the 3-methylindol, the 2-phenylacetic and 3-phenylpropanoic acids were also present in the residues and in the rumen. Although high sensitivity of the methods were used, no glucosinolates and their direct breakdown products were detected in the liquid and the solid content of the rumen. [less ▲]

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See detailComparative evaluation of five hygroscopic condenser humidifiers during short-term postoperative mechanical ventilation
Sottiaux, Thierry; Meurice, F.; Mignolet, Ghislaine ULg et al

in Acta Anaesthesiologica Italica & Anaesthesia and Intensive Care in Italy (1997), 48(1-2), 59-68

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See detailInduction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells.
Polette, M.; Gilles, Christine ULg; Marchand, V. et al

in Clinical & Experimental Metastasis (1997), 15(2), 157-63

Membrane-type matrix metalloproteinase 1 (MT1-MMP) has been recently described as an activator of proMMP-2 (MMP-2) which is involved in tumor invasion. We have shown by in situ hybridization that MT1-MMP ... [more ▼]

Membrane-type matrix metalloproteinase 1 (MT1-MMP) has been recently described as an activator of proMMP-2 (MMP-2) which is involved in tumor invasion. We have shown by in situ hybridization that MT1-MMP is produced by stromal cells in close contact to preinvasive and invasive tumor cells of breast carcinomas. Of particular interest was the observation that some fibroblasts express this enzyme in focal areas in preinvasive lesions, suggesting that particular tumor cells may stimulate fibroblasts to produce MT1-MMP. We have therefore compared the ability of two different breast cancer cell lines, one non-invasive (MCF7) and one invasive (MDA-MB-231) to stimulate MT1-MMP production in human fibroblasts with consequent proMMP-2-activation. The MDA-MB-231 conditioned medium induced MT1-MMP mRNAs in human fibroblasts and a parallel activation of proMMP-2 whereas MCF7 conditioned medium did not have any effect. These results suggest the existence of soluble factor(s) secreted by invasive or some preinvasive breast tumor cells which stimulate fibroblasts to produce and activate MMPs, and emphasize the cooperation between cancer and stromal cells in tumor invasion. [less ▲]

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See detailVieillissement normal, démence d'Alzheimer et mémoire de travail
Van der Linden, Martial ULg; Collette, Fabienne ULg; Andrès Bénito, Pilar

in Psychologie Française (1997), 42

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See detailLa bryoflore d'une forêt alluviale fonctionnelle: la réserve naturelle rhénane de l'Ile de Rhinau (Bas-Rhin, France)
Klein, J. P.; Siebel, H.; Vanderpoorten, Alain ULg

in Mitteilungen des Badischen Landesvereins für Naturkunde und Naturschutz (1997), 16

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See detailAntibodies against vaccinia virus do not neutralize extracellular enveloped virus but prevent virus release from infected cells and comet formation
Vanderplasschen, Alain ULg; Hollinshead, M.; Smith, G. L.

in Journal of General Virology (The) (1997), 78(Pt 8), 2041-2048

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