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See detailUsefulness of Induced Sputum Analysis in Pulmonary Diseases
Kayembe, J. M.; Louis, Renaud ULg; Corhay, Jean-Louis ULg et al

in Acta Clinica Belgica (1997), 52(2), 106-11

In this study, we analysed the cellular component of induced sputum in healthy control subjects (n = 30), asthmatics (n = 44), patients suffering from COPD (n = 15), pulmonary tuberculosis (PTB) (n = 14 ... [more ▼]

In this study, we analysed the cellular component of induced sputum in healthy control subjects (n = 30), asthmatics (n = 44), patients suffering from COPD (n = 15), pulmonary tuberculosis (PTB) (n = 14) and healthy steel workers (HSW) (n = 14). [less ▲]

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See detailAtypical TCA cycle and replenishment in a non-photosynthetic fully habituated sugarbeet callus overproducing polyamines
Bisbis, B.; Kevers, Claire ULg; Gaspar, T.

in Plant Physiology and Biochemistry (1997), 35(5), 363-368

In a fully habituated (hormone independent) white sugarbeet callus overconsuming oxygen, and overproducing polyamines from deviated nitrogen metabolism through glutamate, the question of the synthesis of ... [more ▼]

In a fully habituated (hormone independent) white sugarbeet callus overconsuming oxygen, and overproducing polyamines from deviated nitrogen metabolism through glutamate, the question of the synthesis of the tricarboxylic acid (TCA) cycle intermediates (between (α-cetoglutarate and citrate) was raised. The present paper first completes earlier results indicating an anaplerotic pathway involving non-photosynthetic CO2-fixation with higher activities of phosphoenolpyruvate carboxylase and malate dehydrogenase. Additional original results indicate a second TCA replenishing pathway through a γ-aminobutyric acid (GABA)-shunt from polyamines to succinate, with higher activities of the intermediary enzymes of the habituated callus than in the normal counterpart. Such a GABA-shunt shown to occur frequently in tissues under stress is well in agreement with the formerly proposed permanent stress of the habituated callus. A tentative scheme of this atypical TCA cycle, which also illustrates the interrelationships between the deviated sugar and nitrogen metabolisms in this callus, is presented. [less ▲]

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See detailPrevention and treatment of postmenopausal osteoporosis. National consensus of the Belgian Bone Club"
Kaufman, JM; Devogelaer, JP; Raeman, F et al

in Clinical Rheumatology (1997), 16(4), 343-345

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See detailSurface Molecular Structure of Self-Assembled Alkanethiols Evidenced by UPS and Photoemission with Synchrotron Radiation
Duwez, Anne-Sophie ULg; Di Paolo, Stéphanie; Ghijsen, Jacques et al

in Journal of Physical Chemistry B (1997), 101

With the aim of investigating the configurational and conformational characteristics of monolayers of alkanethiols on gold by means of a photoemission experiment, we compare the valence data obtained from ... [more ▼]

With the aim of investigating the configurational and conformational characteristics of monolayers of alkanethiols on gold by means of a photoemission experiment, we compare the valence data obtained from these layers using synchrotron radiation and ultraviolet photoemission spectroscopy (UPS). The incident energy used for synchrotron radiation has been chosen very close to the Cooper minimum of the 5d levels of gold, in order to limit as much as possible interference from the substrate. The recorded spectra differ markedly from one sample to another, notwithstanding their closely related chemical nature. These variations are compared consistently with semiquantitative simulations on model clusters and found thereby to reflect specifically the influence of the connectivity and of specific interactions on the electronic structure of long hydrocarbon chains [less ▲]

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See detailA new generation of hydrocolloid dressings in combination with topical corticosteroids in the treatment of psoriasis vulgaris
Dezfoulian, Bita ULg; de LA BRASSINNE, Michel ULg; Rosillon, D.

in Journal of the European Academy of Dermatology & Venereology (1997), 9

Aim : A clinical, randomized, parallel, multicenter study was undertaken to compare the efficacy and Ihe tolerability of two known steroid creams, betamethasone 17-valerate and clobetasol propionate ... [more ▼]

Aim : A clinical, randomized, parallel, multicenter study was undertaken to compare the efficacy and Ihe tolerability of two known steroid creams, betamethasone 17-valerate and clobetasol propionate, alone or left under a hydrocolloid dressing (Contreei'* Derma Cover), in the treatment of chronic plaques of psoriasis. Methods : A total of 70 patients with symmetrical localized psoriasis were divided randomly into two groups for the study. Each patient applied ihe corticosteroid preparation under Contreet° Derma Cover once a week on one plaque and the same topical corticosteroid alone h.i.d on the other plaque; the treatment lasted 3 weeks for betamethasone 17-valerate, and 2 weeks for clobetasol propionate. Results : The heahng rate reached 79% with the Contreet" combined treatment versus 15% (P < 0,0001) with the standard treatment for betamethasone 17-valeratc (group I) and Sb% versus 14*70 (P < 0. 0001) for clobetasol propionate (group It). The mean difference in healing rate was 65% {95% confidence interval (C.I), 46-84%) and 69% (95% CL, 50-87%) in groups I and II, respectively. Conclusion : The use of the new generation of hydrocolloid dressings in combination with steroid preparations can be considered as another therapeutic option for the treatment of chronic localized psoriatic lesions. Furthermore, with this method the amount of the topical corticosteroid used can be reduced. [less ▲]

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See detailFibres alimentaires chez le chien : VII. Intérêt dans le traitement diététique de l'animal obèse
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with ... [more ▼]

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with particular emphasis on the incorporation of large quantities of dietary fibres in low-energy specific purpose food. At present time, no conclusions can be drawn from published studies [less ▲]

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See detailGREES recommendations for the Registration of new drugs in the prevention and treatment of osteoporosis
Reginster, Jean-Yves ULg; Compston, J

in Calcified Tissue International (1997), 60

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See detailLe bois de tension. 1 Définition et distribution dans l'arbre.
Jourez, Benoît ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(2), 100-112

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See detailManifestations indésirables des antidépresseurs
Charlier, Corinne ULg; Ansseau, Marc ULg; Pinto, Emmanuel ULg et al

in Toxicorama (1997), (Spécial LYON), 310-314

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See detailAbsolute Configuration Of The Isopyoverdin Chromophore
Michalke, R.; Taraz, K.; Budzikiewicz, H. et al

in Zeitschrift Fur Naturforschung C-A Journal of Biosciences (1997), 52(7-8), 549-550

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See detailRecherche d'information et pragmatisme : II. Utilité sociale de la confirmation d'hypothèses
Dardenne, Benoît ULg; Leyens, J.; Yzerbyt, V. Y.

in Année Psychologique (L') (1997), 97

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See detailInformation transfer between angiographic films and CT images: a tool to delineate the target volume
Tercier, P-A; COUCKE, Philippe ULg; Fankhauser, H et al

in Radiotherapy & Oncology (1997), 45

Abstract Background and purpose: This work was undertaken to improve the definition of target volumes for radiosurgery using the angiographic and CT data. Materials and methods: The basis of this new ... [more ▼]

Abstract Background and purpose: This work was undertaken to improve the definition of target volumes for radiosurgery using the angiographic and CT data. Materials and methods: The basis of this new method is to combine both imaging modalities and to compare them in each representation, i.e. to plot the volume obtained by angiography on CT images and also the contours defined by the CT on angiographic films. To obtain the angiographic volume, the radiographs are taken at several incidence angles. The X-ray sources position and the position of the films are determined using rectangular markers, then the intersection of all the loci of the target volume are calculated. Results: Verifications with a phantom show the accuracy of the procedure and the benefit obtained by increasing the number of angles of incidence in the angiographic imaging. The centre of gravity of the experimental target could be localized to an accuracy of better than 0.4 mm. The method was used in 11 clinical cases with excellent clinical results. Conclusions: The method can be easily applied and improves the delineation of target volumes in radiosurgery. CT data counterbalances the relative weakness of angiography concerning the three-dimensional geometry. Angiography adds useful information on the blood flow that is not shown in CT. Almost all the presented clinical cases benefit from the technique described here. [less ▲]

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See detailEmerging Roles for Proteinases in Cancer
Noël, Agnès ULg; Gilles, Christine ULg; Bajou, Khalid ULg et al

in Invasion & Metastasis (1997), 17(5), 221-39

Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer cure. The contribution of proteinases in these ... [more ▼]

Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer cure. The contribution of proteinases in these processes was initially thought to be the destruction of extracellular matrices. However, recent evidence suggests that they mainly affect tumor growth rather than invasion. Proteinases can indeed generate active matrix protein fragments, influence the release, the activation and the bioavailability of growth factors, and consequently modulate tumor cell growth, apoptosis and angiogenesis. Additionally, proteinases, their receptors and/or inhibitors can be directly involved in cell migration and in the processing or shedding of cell surface proteins. Further elucidation of the functions of proteinases is essential for the development of novel anticancer strategies. [less ▲]

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See detailBiomechanical assessment of the transversalis fascia and rectus abdominis aponeurosis in inguinal herniation - Preliminary results
PANS, Alain ULg; Pierard, Gérald ULg; Albert, Adelin ULg et al

in Hernia : the Journal of Hernias & Abdominal Wall Surgery (1997), 1

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See detailPit-1 gene HinfI RFLP and growth traits in double-muscled Belgian Blue cattle
Renaville, Robert ULg; Gengler, Nicolas ULg; Parmentier, Isabelle et al

in Journal of Animal Science (1997), 75(1), 146

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See detailIn vivo behavior of poly(D,L)-lactide microspheres designed for chemoembolization
Flandroy, P.; Grandfils, Christian ULg; Danen, B. et al

in Journal of Controlled Release (1997), 44(2-3), 153-170

Although chemoembolization advantageously combines arterial embolization of the vascular supply of a neoplasm with controlled intra-arterial infusion of chemotherapeutic drug(s), its application is ... [more ▼]

Although chemoembolization advantageously combines arterial embolization of the vascular supply of a neoplasm with controlled intra-arterial infusion of chemotherapeutic drug(s), its application is limited by the lack of appropriate and reliable embolization materials. Recently, calibrated microspheres of poly(D,L)-lactide have proved to be promising in embolization. Nevertheless, repetitive chemoembolization requires the availability of microspheres degradable within a few days. For this purpose, microspheres consisting of a blend of two polyesters of a very different molecular weight (Mn =65 000 and 3500 in a 16:84 wt. ratio) have been prepared and injected in the renal arteries of rabbits. The in vivo fate of these two component microspheres has been compared by radiology and histology to microspheres prepared from the high molecular weight poly(D,L)-lactide. Furthermore, the in vivo degradation of the polymer has been measured by size exclusion chromatography after quantitative reextraction from the embolized kidney. Degradation kinetics has been compared to data previously reported in vitro. According to the observations performed during the in vivo study, the 50/50 microspheres appear more useful for the chemoembolization of tumors. [less ▲]

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See detailSurveillance of foodborne illnesses in Belgium.
Daube, Georges ULg; Van Look, F.

in Archives of Public Health (1997), 55

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See detailQuantitative ultrasound techniques for the assessment of osteoporosis : Expert agreement on current status
Glüer, CC; Reginster, Jean-Yves ULg

in Journal of Bone and Mineral Research (1997), 12(8), 1280-1288

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See detailUne route mérovingienne en Hautes-Fagnes (La Via Mansuerisca ?). Derniers résultats scientifiques.
Streel, Maurice ULg

in Bulletin de l"Académie Royale de Belgique, Classe Sciences 6e série (1997), VIII(7-12), 367-376

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See detailMusaespora kalbii (lichenized Ascomycetes: Melanommatales), a new foliicolous lichen with a pantropical distribution
Lücking, Robert; Sérusiaux, Emmanuël ULg

in Nordic Journal of Botany (1997), 16

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See detailSIME: A hybrid approach to fast transient stability assessment and contingency selection
Zhang, Ywee; Wehenkel, Louis ULg; Rousseaux, Patricia ULg et al

in International Journal of Electrical Power & Energy Systems (1997), 19(3), 195-208

We propose an integrated scheme for transient stability assessment which in a sequence screens contingencies and scrutinizes only the selected ones. This scheme is based on a hybrid method, called SIME ... [more ▼]

We propose an integrated scheme for transient stability assessment which in a sequence screens contingencies and scrutinizes only the selected ones. This scheme is based on a hybrid method, called SIME for Single Machine Equivalent. SIME relies on a particular direct method coupled with time-domain programs so as to combine the strengths of both, namely: the flexibility with respect to power system modelling of time-domain methods; the speed and richer information of the direct method. This paper lays the foundations of SIME, devises appropriate techniques for transient stability assessment per se and for contingency screening, and finally integrates these two techniques in a fully general function, i.e. able to comply with any power system modelling and stability scenario, and to assess any type of stability limits (critical clearing times or power limits). Throughout, real-world examples illustrate the proposed techniques and highlight their performances. [less ▲]

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See detailInfluence du stade de maturité de la plante de maïs récoltée pour ensilage sur la composition, la digestibilité apparente, les caractéristiques de fermentation dans le rumen et les performances zootechniques chez le taurillon
Mayombo, Asangule Pierre; Dufrasne, Isabelle ULg; Hornick, Jean-Luc ULg et al

in Animal Research (1997), 46(1), 43-55

Un maïs plante entière a été ensilé à trois stades de maturité différents (S1, S2, S3) correspondant à des teneurs respectives en matière sèche de 25,1 (S1), 29,8 (S2) et 32,3 % (S3). La production de ... [more ▼]

Un maïs plante entière a été ensilé à trois stades de maturité différents (S1, S2, S3) correspondant à des teneurs respectives en matière sèche de 25,1 (S1), 29,8 (S2) et 32,3 % (S3). La production de matière sèche s'élevait à 10,7 ; 11,1 et 11,7 tonnes par hectare. Chacun de ces ensilages, distribué à des taureaux à l'engraissement, a été supplémenté par des pulpes séchées, du tourteau de soja, des sels minéraux et des vitamines. Le stade de maturité n'a pas affecté les teneurs en cendres, cendres insolubles, extrait éthéré ou protéines ; cependant une réduction significative de la teneur en fibre ADF a été enregistrée avec S3. La digestibilité de la matière sèche et de la matière organique de la ration mesurée in vivo sur des taureaux en cages à bilan ainsi que celle du maïs ensilage n'ont pas été non plus influencées par le stade de maturité. En revanche, la digestibilité de la fibre ADF a été significativement plus faible pour S3 par rapport à S1 et S2 (62,1 vs 67,2 ou 65,6 %, p < 0,05 pour la ration; 54,1 vs 63,3 ou 60,7 %, p < 0,001 pour le maïs). Quant aux potentialités du rumen à dégrader les aliments, il est à noter que la dégradabilité totale par la méthode in sacco des différents composants testés a été supérieure dans le rumen des animaux qui recevaient le maïs à teneur en matière sèche élevée. Il n'y a pas eu d'effets significatifs du stade de maturité sur les performances animales durant un essai de 5,5 mois dans le cas d'une alimentation ad libitum. A partir de l'indice de consommation, du gain total de poids vif et de la production de matière sèche par hectare, il était possible d'estimer que 13,8, 14,2 et 15,7 taurillons pouvaient être engraissés respectivement à partir des ensilages de maïs S1, S2 et S3 produits par ha. [less ▲]

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See detailThe Cloning And Sequencing Of An Ovine C-Myc Cdna
Kiermer, V.; Dequiedt, Franck ULg; Masengo, R. et al

in DNA Sequence : The Journal of DNA Sequencing & Mapping (1997), 7(3-4),

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See detailSurface-active properties of surfactin iturin A mixtures produced by Bacillus subtilis
Razafindralambo, Hary ULg; Popineau, Yves; Deleu, Magali ULg et al

in Langmuir (1997), 13(23), 6026-6031

Surface-active properties including dynamic adsorption, monolayer stability, micelle forming capacity, and foaming aptitudes of surfactin-C-15/iturin A-C-15 mixtures were studied. Surfactin-C-15 and ... [more ▼]

Surface-active properties including dynamic adsorption, monolayer stability, micelle forming capacity, and foaming aptitudes of surfactin-C-15/iturin A-C-15 mixtures were studied. Surfactin-C-15 and iturin A-C-15 molecules interact in synergism on the most surface-active properties evaluated at 20 degrees C at the air-water interface and in aqueous solution (pH 8.0). The synergism is positive on the adsorption effect, monolayer stability, foam density, and liquid stability in foam, whereas it is negative on the adsorption rate. No synergism occurs an micelle forming capacity, but surfactin-C-15 and iturin A-C-15 form mixed micelles when the solution contains a low proportion of surfactin-C-15.ses the synergistic effect is maximum when surfactin-C-15 and iturin A-C-15 molecules are mixed in a 2:3 ratio. This is attributed to the surfactin/iturin A complex formation resulting from specific interactions among two surfactin-C-15 molecules and three iturin A-C-15 molecules. A model of such a complex formation is proposed. [less ▲]

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See detailRetrieval of ozone vertical column amounts from ground-based high resolution infrared solar spectra
Hamdouni, A.; Barbe, Alain; Demoulin, Philippe ULg et al

in Journal of Quantitative Spectroscopy & Radiative Transfer (1997), 57(1), 11-22

Good infrared spectral regions to retrieve accurately the vertical column amount of ozone from ground observations are proposed. Their selection was based on studies of the influence of spectroscopic ... [more ▼]

Good infrared spectral regions to retrieve accurately the vertical column amount of ozone from ground observations are proposed. Their selection was based on studies of the influence of spectroscopic (frequencies, half-widths, intensities) as well as geophysical parameters (volume mixing ratios, temperature profiles) with a particular attention for temperature. The results, obtained in three different spectral regions, with a realistic T-profile are very consistent. [less ▲]

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See detailBWGIC guidelines for training and quality control in adult interventional cardiology. Belgian Working Group of Invasive Cardiology.
Legrand, Victor ULg; Vrolix, M.; De Bruyne, B. et al

in Acta cardiologica (1997), 52(6), 507-14

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See detailMolecular dissection of the insulin-like growth factor axis in the human thymus
Geenen, Vincent ULg; Kecha, Ouafae; Achour, Imane et al

in Diabetologia (1997), 40

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See detailGezonheidszorg : actuele standpunten. Diagnostiek van osteoporose
Devogelaer, JP; Reginster, Jean-Yves ULg; Raeman, F et al

in Tijdschrift voor Geneeskunde (1997), 53(10), 639-645

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See detailSubtotal hysterectomy in patients with endometriosis--an option.
NISOLLE, Michelle ULg; Donnez, Jacques

in Fertility and Sterility (1997), 67(6), 1185-7

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See detailQuelques arthropodes de nos maisons
Loneux, Michèle ULg

in Cahiers d'Ethologie (1997), 17(1), 75-124

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See detailGrecs, Romains et Barbares. A la recherche de l'identité ethnique et linguistique des Grecs et des Romains
Rochette, Bruno ULg

in Revue Belge de Philologie et d'Histoire (1997), 75

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See detailEndoscopic laser treatment of uterine malformations.
Donnez, Jacques; NISOLLE, Michelle ULg

in Human Reproduction (1997), 12(7), 1381-7

Hysteroscopic resection of an intrauterine septum may benefit patients suffering from infertility or recurrent pregnancy loss. A partial or complete uterine septum can be easily resected using a Nd-YAG ... [more ▼]

Hysteroscopic resection of an intrauterine septum may benefit patients suffering from infertility or recurrent pregnancy loss. A partial or complete uterine septum can be easily resected using a Nd-YAG laser. If present, the vaginal septum may also be removed during the same procedure. The reproductive outcome of women treated by operative hysteroscopy for an intrauterine septum is reviewed. To avoid pregnancy in a non-communicating rudimentary horn, the removal of the horn and the homolateral tube may be performed by either bipolar coagulation or a CO2 laser. [less ▲]

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See detailOnset Time of Neuromuscular Block and Intubating Conditions: Influence of Different Stimulation Patterns
Hans, Pol ULg; Dewé, Walthère ULg; Albert, Adelin ULg

in Acta Anaesthesiologica Belgica (1997), 48(1), 15-21

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See detailPrimary radiation therapy or surgery combined or not to radiation therapy in the management of squamous cell carcinoma of the penis
Zouhair, Abderrahim; Ozsahin, Mahmut; Douglas, Pelham et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 39(2 (Supplément)), 295

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See detailThe Nucleotide Sequence Of Saccharomyces Cerevisiae Chromosome Vii
Tettelin, H.; Carbone, Mla.; Albermann, K. et al

in Nature (1997), 387(6632),

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See detailAutour de Benjamin et Arendt
Delruelle, Edouard ULg

in Revue belge de Cinéma (1997), 41

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See detailOrientation des objectifs et participation à des activités sportives
Ledent, Maryse; Telama, Risto; Cloes, Marc ULg et al

in Sport (1997), 159/160

Il existe une multitude de facteurs d'influence qui rendent la prévision d'une participation à l'activité sportive particulièrement délicate: influences biologiques et démographiques, psychologiques ... [more ▼]

Il existe une multitude de facteurs d'influence qui rendent la prévision d'une participation à l'activité sportive particulièrement délicate: influences biologiques et démographiques, psychologiques, sociales et environnementales. ... [less ▲]

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See detailVrbis-Orbis (Ovide, Fastes, II, 684)
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (1997), 56(3), 551-553

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See detailLes moyens de se prémunir contre la défaillance de ses cocontractants
Georges, Frédéric ULg

in Actualités du Droit (1997)

Cette contribution commentait l'impact de la réforme de 1997 du droit de l'insolvabilité sur les droits des créanciers

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See detailLe contrôle des juridictions de fond sur la désignation par procureur général du magistrat compétent en application de l'article 155, alinéa 2, du Code judiciaire
Michiels, Olivier ULg

in Journal des Tribunaux (1997)

La note publiée sous un arrêt prononcé par la Cour de cassation le 8 octobre 1996 fait le point sur le contrôle par les juridictions de fond sur la désignation par procureur général du magistrat compétent ... [more ▼]

La note publiée sous un arrêt prononcé par la Cour de cassation le 8 octobre 1996 fait le point sur le contrôle par les juridictions de fond sur la désignation par procureur général du magistrat compétent en application de l'article 155, alinéa 2, du Code judiciaire pour exercer les poursuites devant les juridictions répressives dans les hypothèses de concours entre des infractions de droit commun et de droit pénal social. [less ▲]

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See detailUse of recombinant human erythropoietin after allogeneic bone marrow transplantation
Hermanne, J.-P.; Beguin, Yves ULg

in Erythropoiesis (1997), 8

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See detailEffects of meloxicam compared to acetylsalicylic acid in human articular chondrocytes
Bassleer, Corinne; Magotteaux, Jacques ULg; Geenen, Vincent ULg et al

in Pharmacology (1997), 54

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See detailMechanisms of Hand Motor Recovery After Stroke: An Electrophysiologic Study of Central Motor Pathways
Bastings, Eric; Rapisarda, Giuseppe; Pennisi, Giovanni et al

in Journal of Neurologic Rehabilitation (1997), 11(2), 97-108

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See detailMultiple pregnancy-associated glycoproteins are secreted by day 100 sheep placenta
Xie, Sancai; Green, Jonathan; Bao, Bagna et al

in Biology of Reproduction (1997), 57(6), 1384-1393

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep ... [more ▼]

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep and other ruminants produce similar products. There is evidence, however, that these antigens, which are related structurally to the pepsinogens and other aspartic proteinases, are not single gene products but members of an extensive family. Here, the sequential use of ammonium sulfate precipitation and Sepharose blue, anion-exchange, and cation-exchange chromatographies, as well as isoelectric elution from a Mono P column, has allowed several PAG1-related molecules to be purified from the medium after culture of explants from Day 100 sheep placentas. Each of these PAGs cross-reacted to a varying extent with a panel of three different anti-PAG1 antisera. Four of them, all of which were major secretory products of the placenta, were subjected to amino-terminal microsequencing. Although each was related to ovine (ov) PAG1, none was identical. Reverse transcription-polymerase chain reaction was then used to amplify PAG1-related cDNA from Day 100 placental RNA. Seven novel full-length cDNA, all distinct from ovPAG1, were identified from 25 cDNA selected for sequencing. Only two of these (ovPAG3 and ovPAG7) encoded polypeptides identical in sequence at their inferred amino termini to one of the PAGs (ovPAG65) purified from explant cultures. Even so, they were only 84% identical in overall sequence. The remaining five cDNA were unique. In situ hybridization analysis revealed that expression of ovPAG3 and ovPAG7, like that of ovPAG1, is confined to trophoblast binucleate cells. The data confirm that at Day 100 of pregnancy the ovine placenta produces many different PAGs, which differ considerably in sequence and immunological cross-reactivity. [less ▲]

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See detailReactivite bronchique chez les patients diabetiques.
Piéron, Maurice ULg; Scheen, André ULg; Corhay, Jean-Louis ULg et al

in Revue des Maladies Respiratoires (1997), 14(5), 379-85

The data of the literature concerning bronchial reactivity in diabetic patients are controversial. Therefore, we studied the influence of the presence of a diabetic cardiac autonomic neuropathy (CAN) on ... [more ▼]

The data of the literature concerning bronchial reactivity in diabetic patients are controversial. Therefore, we studied the influence of the presence of a diabetic cardiac autonomic neuropathy (CAN) on the ventilatory parameters measured during a methacholine-induced bronchoconstriction test. Ten insulin-dependent diabetic patients without CAN, ten insulin-dependent diabetic patients with CAN and ten healthy volunteers, all non-smokers and free of respiratory symptoms, have undergone a functional respiratory check-up before the methacholine test. The presence of CAN was classically studied by the decrease in heart rate changes during three standardized tests (deep breathing at 6 cycles/min, Valsalva manoeuver, orthostatism) which all mainly explore the parasympathetic function. The bronchial response to methacholine was similar in the healthy subjects and in the diabetic patients without CAN. However, the fall in forced expiratory volume in 1 second induced by the highest dose of methacholine was significantly less marked in the diabetic subjects with CAN than in the two other groups. These results suggest that the diabetic autonomic neuropathy also involves the vagal innervation of the respiratory tract. [less ▲]

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See detailApparition tardive d'une infertilité masculine
Geenen, Vincent ULg; PERRIER d'HAUTERIVE, Sophie ULg

in Actualité Médicale Belge (1997), 565

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See detailLa problématique de la matière grasse : aspects théoriques
Thonart, Philippe ULg; Destain, Jacqueline ULg; Antoine, P. et al

in Tribune de l'Eau (La) (1997), 586/2

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See detailAnévrysme ou pseudoanévrysme ventriculaire?
Toussaint, A.C.; Waleffe, André ULg; Pierard, Luc ULg et al

in Revue Médicale de Liège (1997), 52(7), 457-62

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See detailSeminoma arising in corrected and uncorrected inguinal cryptorchidism: treatment and prognosis in 66 patients
Li, Y-X; COUCKE, Philippe ULg; Qian, T-L et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 36

Purpose: The purpose of this study was to analyze prognosis and treatment results for seminoma arising in corrected and uncorrected inguinal cryptorchidism (SCIC and SUIC). Methods and Materials: We ... [more ▼]

Purpose: The purpose of this study was to analyze prognosis and treatment results for seminoma arising in corrected and uncorrected inguinal cryptorchidism (SCIC and SUIC). Methods and Materials: We reviewed 66 patients with inguinal seminomas between June 1958 and December 1991 at the Cancer Hospital and Institute of Chinese Academy of Medical Sciences. Of these patients, 23 had prior orchiopexy and 43 presented with an inguinal form of cryptorchidism. At presentation, 17 of 66 (26%) patients had nodal metastases. This nodal involvement was 30% (7 of 23) for SCIC and 23% (10 of 43) for SUIC, respectively. These numbers are comparable with those in a series of patients treated for scrotal seminoma at our institution (26% vs. 20%). However, 3 of 23 (13%) patients who had prior orchiopexy presented with inguinal nodal metastasis as compared with 0 of 43 patients with SUIC or 4 of 237 patients with scrotal seminoma (p < .05). There were 49 stage I, 5 stage IIA, 8 stage IIB, 3 stage III, and 1 stage IV patients. All patients underwent radical orchiectomy and received further radiotherapy, chemotherapy, or both. Patients with stage I and stage II disease were treated primarily with radiotherapy, whereas patients with stage III and IV disease were treated with chemotherapy. Results: The overall and disease-free survival at 5 and 10 years was 94% and 92%, 89% and 87%, respectively. The overall 5- and lo-year survival by stage was 100% and 100% for stage I, and 77% and 68% for stage II, respectively @ < .05). There was no significant difference in survival between SUIC and SCIC (93% vs. 96% at 5 years). Four patients developed relapse. Two of these four patients experienced relapse at the inguinal area, due to a marginal miss. Three of four patients with relapse were successfully salvaged, and one died of disease. Conclusion: Our results indicate that prognosis for inguinal seminoma is excellent and similar to that of scrotal seminoma. Postorchiectomy radiotherapy can be considered as the standard treatment for stage I and IIA inguinal seminoma. We recommend routinely including the para-aortic and ipsilateral pelvic nodes. 0 1997 Elsevier Science Inc. [less ▲]

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See detailÀ propos de l'authenticité de la momie attribuée à Thoutmosis III (CG 61068)
Laboury, Dimitri ULg

in Göttinger Miszellen. Beiträge zur ägyptologischen Diskussion (1997), 156

L'article examine les différents arguments qui ont été avancés pour contester l'authenticité de la momie attribuée à Thoutmosis III (CG 61068). A l'issue de l'analyse, il apparaît qu'aucun ne résiste à la ... [more ▼]

L'article examine les différents arguments qui ont été avancés pour contester l'authenticité de la momie attribuée à Thoutmosis III (CG 61068). A l'issue de l'analyse, il apparaît qu'aucun ne résiste à la critique. En revanche, la découverte de cette momie dans un des cercueils originaux du roi, avec le linceul initial du souverain,- sans doute enroulé autour d'elle,- constitue un indice très sérieux en faveur de cette attribution. [less ▲]

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See detailUltrastructural nucleolar alterations induced by an ametantrone/polyr(A-U) complex.
Thiry, Marc ULg; Jamison, J. M.; Gilloteaux, J. et al

in Experimental Cell Research (1997), 236(1), 275-84

In the present study we examined the ultrastructural modifications as well as the precise distribution of DNA and RNA in RT4 cell nucleoli following a 3-h exposure to nontoxic or toxic doses of ... [more ▼]

In the present study we examined the ultrastructural modifications as well as the precise distribution of DNA and RNA in RT4 cell nucleoli following a 3-h exposure to nontoxic or toxic doses of ametantrone (AMT), poly(adenylate-uridylate) (polyr(A-U), or an AMT/polyr(A-U) combination. While distribution of nucleic acids within the various nucleolar components is not modified following all treatments, the nucleoli exhibit several ultrastructural changes: redistribution of the nucleolar components, decrease in the number of fibrillar centers, and increase in the size of the fibrillar centers. The relative frequencies of the test agents to induce the apparition of nucleoli of compact type are AMT/polyr(A-U) > AMT approximately polyr(A-U) > sham-treated, while the abilities of the test agents to induce the nucleolar segregation are AMT/polyr(A-U) approximately AMT > polyr(A-U) > sham-treated cells. These ultrastructural changes are characteristics of drugs that intercalate into DNA and inhibit rDNA transcription as well as rRNA processing and release of nascent preribosomes from the nucleolus. [less ▲]

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See detailSynthesis of resorcinol-formaldehyde aeroels by the freeze-drying methods
Mathieu, Bernard; Michaux, Bernard; Pirard, René ULg et al

in Annales de Chimie Science des Materiaux (1997), 22

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See detailMiospores from the type locality of the Middle Famennian Esneux Formation in the Ourthe Valley, eastern Belgium
Loboziak, S.; Avkhimovitch, V.I.; Streel, Maurice ULg

in Annales de la Société Géologique de Belgique (1997), 119(2), 111-118

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See detailPratique et importance des principales activités de loisirs chez des jeunes de 12 et 15 ans dans cinq pays européens
Cloes, Marc ULg; Ledent, Maryse; Didier, Pascale et al

in Sport (1997), 159/160

On admet généralement que les loisirs sont devenus une expression du style de vie dans les pays industrialisés. Dans ce contexte, la place qu'ils occupent dans le secteur social et dans le monde ... [more ▼]

On admet généralement que les loisirs sont devenus une expression du style de vie dans les pays industrialisés. Dans ce contexte, la place qu'ils occupent dans le secteur social et dans le monde économique semble croître régulièrement. Les comparaisons interculturelles des activités de loisirs s'avèrent très difficiles en raison des différences enregistrées dans la conception des instruments utilisés dans les enquêtes et dans les intérêts des équipes de recherche. ... [less ▲]

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See detailLes attitudes de jeunes Européens à l’égard de l’école et du cours d’éducation physique
Delfosse, Catherine; Ledent, Maryse; Carreiro da Costa, Francisco et al

in Sport (1997), 159/160

L'essentiel de la vie quotidienne des jeunes scolarisés s'organise entre le temps passé à l'école et des activités dites de loisirs. Une différence fondamentale sépare les deux domaines. Le premier, par ... [more ▼]

L'essentiel de la vie quotidienne des jeunes scolarisés s'organise entre le temps passé à l'école et des activités dites de loisirs. Une différence fondamentale sépare les deux domaines. Le premier, par son caractère obligatoire, concerne tous les enfants. Le second relève davantage du niveau social, économique et culturel des parents et nécessite une organisation familiale parfois complexe. On peut affirmer que tous les enfants ne disposent pas de chances égales de s'engager dans une pratique sportive organisée ou non organisée. ... [less ▲]

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See detailClostridium spiroforme toxin genes are related to C. perfringens iota toxin genes but have a different genomic localization.
Gilbert, M.; Perelle, S.; Daube, Georges ULg et al

in Systematic & Applied Microbiology (1997), 20

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See detailParticipation des jeunes Européens aux activités physiques et sportives
Ledent, Maryse; Cloes, Marc ULg; Telama, Risto et al

in Sport (1997), 159/160

Le rôle primordial que jouent les activités physiques et sportives en matière de prévention de plusieurs maladies parfois fatales survenant à l'âge adulte constitue un argument essentiel en faveur d'une ... [more ▼]

Le rôle primordial que jouent les activités physiques et sportives en matière de prévention de plusieurs maladies parfois fatales survenant à l'âge adulte constitue un argument essentiel en faveur d'une pratique régulière de l'effort physique. Ses effets sur la santé, ou plus précisément sur les facteurs de risque chez les adultes, ont suscité l'éveil d'un nombre croissant de chercheurs. ... [less ▲]

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See detailStability margins of nonlinear receding horizon control via inverse optimality
Magni, L.; Sepulchre, Rodolphe ULg

in Systems & Control Letters (1997), 32(4), 241-245

Using the nonlinear analog of the Fake Riccati equation developed for linear systems, we derive an inverse optimality result for several receding horizon control schemes. This inverse optimality result ... [more ▼]

Using the nonlinear analog of the Fake Riccati equation developed for linear systems, we derive an inverse optimality result for several receding horizon control schemes. This inverse optimality result unifies stability proofs and shows that receding horizon control possesses the stability margins of optimal control laws. [less ▲]

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See detailPenicillin-binding proteins. Wall peptidoglycan assembly and resistance to penicillin: facts, doubts and hopes
Ghuysen, Jean-Marie ULg; Charlier, Paulette ULg; Coyette, Jacques ULg et al

in International Journal of Antimicrobial Agents (1997), 8(1), 45-60

As the protein sequence and structure databases expand, the relationships between proteins, the notion of protein superfamily, and the driving forces of evolution are better understood. Key steps of the ... [more ▼]

As the protein sequence and structure databases expand, the relationships between proteins, the notion of protein superfamily, and the driving forces of evolution are better understood. Key steps of the synthesis of the bacterial cell wall peptidoglycan are revisited in light of these advances. The reactions through which the D-alanyl-D-alanine depeptide is formed, utilized, and hydrolyzed and the sites of action of the glycopeptide and β-lactam antibiotics illustrate the concept according to which new enzyme functions evolve as a result of tinkering of existing proteins. This occurs by the acquisition of local structural changes, the fusion into mul-timodular polypeptides, and the association into multiprotein complexes. [less ▲]

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See detailLow Thiamine Diphosphate Levels in Brains of Patients with Frontal Lobe Degeneration of the Non-Alzheimer's Type
Bettendorff, Lucien ULg; Mastrogiacomo, Frank; Wins, Pierre et al

in Journal of Neurochemistry (1997), 69(5), 2005-2010

We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or ... [more ▼]

We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or frontotemporal dementia with five age-, postmortem delay-, and agonal status-matched control subjects. Our results reveal a 40-50% decrease in thiamine diphosphate (TDP) in the cortex of FNAD patients, whereas thiamine monophosphate was increased 49-119%. TDP synthesizing and hydrolyzing enzymes were unaffected. The activity of citrate synthase, a mitochondrial marker enzyme, was decreased in the frontal cortex of patients with FNAD, but no correlation with TDP content was found. These results suggest that decreased contents of TDP, which is essentially mitochondrial, is a specific feature of FNAD. As TDP is an essential cofactor for oxidative metabolism and neurotransmitter synthesis, and because low thiamine status (compared with other species) is a constant feature in humans, a nearly 50% decrease in cortical TDP content may contribute significantly to the clinical symptoms observed in FNAD. This study also provides a basis for a trial of thiamine, to improve the cognitive status of the patients. [less ▲]

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See detailStudies on the O-J-I-P transient of chlorophyll fluorescence in relation to photosystem II assembly and heterogeneity in plastids of greening barley
Barthelemy, X.; Popovic, R.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (1997), 39(3), 213-218

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of ... [more ▼]

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of etiolated leaves of Hordeum vulgare. The initial photochemical phase (O-J) due to reduction of the primary quinone acceptor Q(A) was found to represent a constant proportion (65-70%) of total variable fluorescence independent of greening time. The partial fluorescence quenching in the Q(A)-reduced state seems, therefore, to represent a basic property of PSII electron transport. The biphasic character of the slower J-I-P transient due to reduction of the plastoquinone pool developed progressively during the first hours of greening. in the same period of lime the proportion and rate constant of rapid PSII alpha sub-population increased, as calculated from the induction curve in the presence of DCMU. Etiochloroplasts or chloroplasts resuspended in low salt medium showed a low I level, which was restored upon readdition of 5 mM MgCl2 and NaCl. Salts also increased the apparent proportion of PSII alpha. These results suggest that the J-I and I-P phases of the induction curve are related to different rates of plastoquinone photoreduction by two distinct PSII populations. The effects of DMQ and of DCBQ on the O-J-I-P transient were also studied in (etio-)chloroplasts, In addition to the already reported quenching of the initial (F-0) and variable fluorescence by DCBQ, a slow fluorescence increase phase was found to appear upon the addition of DCBQ but not of DMQ. The latter observations confirm that DCBQ differs from DMQ by its higher efficiency as PSII electron acceptor. (C) 1997 Elsevier Science S.A. [less ▲]

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See detailRectovaginal septum adenomyotic nodules: a series of 500 cases.
Donnez, Jacques; NISOLLE, Michelle ULg; Gillerot, Stépane et al

in British Journal of Obstetrics & Gynaecology (1997), 104(9), 1014-8

OBJECTIVE: Laparoscopic procedure with excision of deep fibrotic endometriotic nodules of the rectovaginal septum and histological study of the lesions. SETTING: An academic teaching hospital ... [more ▼]

OBJECTIVE: Laparoscopic procedure with excision of deep fibrotic endometriotic nodules of the rectovaginal septum and histological study of the lesions. SETTING: An academic teaching hospital. PARTICIPANTS: A series of 500 women undergoing laparoscopy for pelvic pain or infertility. RESULTS: Laparoscopic (n = 497) and laparotomic (n = 3) excision of endometriotic nodules resulted in considerable pain relief. Histologically the rectovaginal nodule was similar to an adenomyoma as it was a circumscribed nodular aggregate of smooth muscle and endometrial glands and stroma. The variations in oestrogen receptor and progesterone receptor content suggested a regulatory mechanism different from that of eutopic endometrium. CONCLUSION: This form of disease should be considered as an entity distinct from peritoneal and ovarian endometriosis, and originating from the Müllerian rests present in the rectovaginal septum. [less ▲]

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See detailLe diagnostic de la reproduction: fertilité, gestation, anœstrus
Delahaut, Philippe; Sulon, Joseph ULg; Ectors, Francis et al

in Cahiers Agricultures (1997), 6

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See detailNucleon nucleon interaction in a chiral constituent quark model
Stancu, Floarea ULg; Pepin, S.; Glozman, L Ya

in Physical Review. C : Nuclear Physics (1997), C56

We study the short-range nucleon-nucleon interaction in a chiral constituent quark model by diagonalizing a Hamiltonian comprising a linear confinement and a Goldstone boson exchange interaction between ... [more ▼]

We study the short-range nucleon-nucleon interaction in a chiral constituent quark model by diagonalizing a Hamiltonian comprising a linear confinement and a Goldstone boson exchange interaction between quarks. The six-quark harmonic oscillator basis contains up to two excitation quanta. We show that the highly dominant configuration is $\mid s^4p^2[42]_O [51]_{FS}>$ due to its specific flavour-spin symmetry. Using the Born-Oppenheimer approximation we find a strong effective repulsion at zero separation between nucleons in both $^3S_1$ and $^1S_0$ channels. The symmetry structure of the highly dominant configuration implies the existence of a node in the S-wave relative motion wave function at short distances. The amplitude of the oscillation of the wave function at short range will be however strongly suppressed. We discuss the mechanism leading to the effective short-range repulsion within the chiral constituent quark model as compared to that related with the one-gluon exchange interaction. [less ▲]

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See detailLa prééclampsie est la conséquence d'un déficit de placentation: de la biologie aux considérations cliniques
Maquoi, Erik ULg; Schaaps, Jean-Pierre ULg; Jacobs, J. L. et al

in Revue Médicale de Liège (1997), 52(7), 478-84

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See detailInfluence of Diazepam on Contingent Negative Variation
Papart, Patrick ULg; Ansseau, Marc ULg; Timsit-Berthier, M.

in Human Psychopharmacology (1997), 12

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See detail"De l'Olympe au réseau..." Comment les philologues classiques allemands font face aux réalités contemporaines
Rochette, Bruno ULg

in Bulletin de la Fédération des Professeurs de Grec et de Latin (1997), 108(septembre-octobre), 6-7

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See detailLa tracabilite des viandes.
Portetelle, Daniel ULg; Renaville, Robert ULg

in Annales de Gembloux (1997), 103(1-2),

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See detailEmergency Coronary Stenting with Wiktor Stent N Immediate and Late Results.
Bertrand, Olivier; Legrand, Victor ULg; Bilodeau et al

in The Journal of invasive cardiology (1997), 9(1), 2-9

In case of failed angioplasty, coronary stenting has gradually emerged as a non-surgical method to restore vessel patency and optimize coronary blood flow. There is still little clinical and angiographic ... [more ▼]

In case of failed angioplasty, coronary stenting has gradually emerged as a non-surgical method to restore vessel patency and optimize coronary blood flow. There is still little clinical and angiographic information on the use of radiopaque single loose interdigitating wire stents in angioplasty complicated by threatened or acute closure. Seventy-one patients received Wiktor stents after threatened vessel closure in 53 cases and acute closure in 18 cases. Stent delivery was successful in 98%. In-hospital death occurred in 1 case (1.4%). Stents occlusion were faced in 10 cases (14%), of which 6 presented early and 4 late after the procedure. Urgent bypass surgery was needed in 9 cases (12%) and 7 patients (10%) developed acute myocardial infarction. Serious bleeding complications occurred in 7 cases (10%) and vascular repair was performed in 4 patients (5%). During a follow-up of 20 +/- 10 months, 2 patients died, no myocardial infarction was observed and recurrence of angina was noted in 17 patients (24%). Angiographic analysis showed an acute gain in minimal lumen diameter of 1.71 +/- 0.22 mm and a late loss of 0.63 +/- 0.17 mm. Angiographic restenosis (diameter stenosis > 50%) presented in 20% of patients. Therefore, Wiktor stenting yields similar results than currently used stents in acute closure and strictly defined threatened vessel closure following angioplasty. [less ▲]

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See detail5-(Diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide : Synthesis and Evaluation of Spin Trapping Properties
Roubaud, Valérie; Mercier, Anne; Olive, Gilles ULg et al

in Journal of the Chemical Society. Perkin Transactions 2 (1997), 9

A new spin trap, the 5-(diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide (3), is prepared through a four-step synthetic route. The in vitro spin trapping properties of 3 have been ... [more ▼]

A new spin trap, the 5-(diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide (3), is prepared through a four-step synthetic route. The in vitro spin trapping properties of 3 have been investigated and the hydroxyl and superoxide spin adducts characterised. The persistence of the superoxide spin adduct obtained with 3 is compared with those of the analogues obtained with DEPMPO [5-(diethoxyphosphoryl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide] and DMPO in both phosphate buffer and pyridine. In 0.1 M phosphate buffer at pH 7.0, the HOO-3? adduct is found to be 2.8 times more persistent than HOO-DMPO?, but 5.7 times less than HOO-DEPMPO?. In phosphate buffer, HOO-3? decomposes to give HO-3?. The stereoselectivity of the addition of free radicals on 3 is generally poor, and mixtures of diastereomers have been observed by EPR. The overall spin trapping behaviour of nitrone 3 is more similar to that of DMPO than that of DEPMPO. [less ▲]

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See detailAirborne dust and aeroallergen concentrations in different sources of feed and bedding for horses
Vandenput, Sandrina ULg; Istasse, Louis ULg; Nicks, Baudouin ULg et al

in Veterinary Quarterly (The) (1997), 19(4), 154-158

Standardized methods were used to make quantitative and qualitative assessments of respirable dust and aeroallergens in feed and bedding for horses. Concentrations of airborne dust were measured by using ... [more ▼]

Standardized methods were used to make quantitative and qualitative assessments of respirable dust and aeroallergens in feed and bedding for horses. Concentrations of airborne dust were measured by using a Rion particle counter, and levels of major aeroallergens implicated in chronic obstructive pulmonary disease were measured by using an Andersen sampler. Laboratory conditions allowed comparison of the different sources of forage, supplements, and bedding without external influences such as ventilation, external temperature and horse activity affecting the result. Grass silages of approximately 50% dry matter and alfalfa pellets appeared to be very good sources of forage with low levels of dust and aeroallergens. The studied good quality straw was significantly less dusty with fewer allergens than the wood shavings. Supplements, such as whole grains and molassed concentrates, contained many respirable particles and aeroallergens. Rolled grains were significantly more dusty than good hay. [less ▲]

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See detailLoss of type IV collagen alpha 5 and alpha 6 chains in human invasive prostate carcinomas
Dehan, Pierre ULg; Waltregny, David ULg; Beschin, Alain et al

in American Journal of Pathology (1997), 151(4), 1097-104

Type IV collagen, a major component of basement membranes, is organized in a network responsible for the mechanical resistance of the basement membranes. It also plays a key role in epithelial cell ... [more ▼]

Type IV collagen, a major component of basement membranes, is organized in a network responsible for the mechanical resistance of the basement membranes. It also plays a key role in epithelial cell adhesion to basement membranes. This study was designed to investigate the distribution of type IV collagen alpha-chains in normal, preneoplastic, and malignant prostate basement membranes. For this purpose, immunohistochemistry using specific antibodies raised against the different alpha-chains of type IV collagen was performed in eight normal samples, six prostatic intraepithelial neoplasia, and 20 malignant lesions of the prostate. Our results demonstrate the presence of the "novel" alpha 5 (IV) and alpha 6 (IV) chains along with the "classical" alpha 1 (IV)/alpha 2 (IV) chains in the basement membrane of the normal prostate gland. The alpha 3 (IV) chain was never detected in any prostate specimen. Prostatic intraepithelial neoplasia showed a similar immunostaining pattern to that found in normal glands. In cancer gland basement membranes, we demonstrate for the first time a specific loss of the alpha 5 (IV) and alpha 6 (IV) chains, whereas the classical alpha 1 (IV) and alpha 2 (IV) chains were consistently exhibited. Additionally, type VII collagen colocalized with alpha 5 (IV) collagen chain, and these two proteins, which were always observed in normal and prostatic intraepithelial neoplasia gland basement membranes, were lost in invasive carcinoma basement membranes. This observation raises questions about the possible association or cooperation between alpha 5 (IV)/alpha 6 (IV) chains and anchoring fibrils in prostate glands basement membrane. [less ▲]

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See detailRhômé = rhômé
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (1997), 56(1), 54-57

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See detailDifferential expression of c-fos, Hsp70 and Hsp27 after photothrombotic injury in the rat brain.
Plumier, Jean-Christophe ULg; Armstrong, J. N.; Wood, N. I. et al

in Molecular Brain Research (1997), 45(2), 239-46

In situ hybridization and immunohistochemistry were used to examine the expression of c-fos, Hsp70 and Hsp27 following photothrombotic injury in the right fronto-parietal cortex of the rat. C-fos mRNA and ... [more ▼]

In situ hybridization and immunohistochemistry were used to examine the expression of c-fos, Hsp70 and Hsp27 following photothrombotic injury in the right fronto-parietal cortex of the rat. C-fos mRNA and protein were detected in the entire cerebral cortex on the lesioned side. Hsp70 mRNA accumulation was observed only adjacent and peripheral to the site of the lesion. At 1 h after photothrombotic injury, Hsp70 expression delineates the area of necrosis at 24 h after photothrombotic injury. Hsp27 protein was observed in the ipsilateral cerebral cortex with the exception of the deep layers of the cingulate cortex. In addition, while c-Fos immunoreactivity was localized in cell nuclei, Hsp27 immunoreactivity was detected in the cytoplasm of astrocytes. These results demonstrate that unilateral cortical injury induces changes in gene expression that vary according to cell type and brain region. [less ▲]

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See detaill'application des dispositions pénales générales en matière bancaire et boursière
Flore, Daniel ULg

in Revue de Droit Commercial Belge [= RDC] = Tijdschrift voor Belgisch Handelsrecht [=TBH] (1997), 4

L'objectif est de dresser un cadre pénal général pour l'approche du droit pénal bancaire et boursier.

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See detailSurveys of ultraviolet-excess quasar candidates in large fields
Gosset, Eric ULg; Moreau, O.; Surdej, Jean ULg et al

in Astronomy and Astrophysics. Supplement Series (1997), 123

We describe the results of a survey for moderately bright quasars performed in a 20.6-square-degree field around the galaxy NGC 450. The quasar candidates were selected on the basis of their ultraviolet ... [more ▼]

We describe the results of a survey for moderately bright quasars performed in a 20.6-square-degree field around the galaxy NGC 450. The quasar candidates were selected on the basis of their ultraviolet excess: by comparative visual inspection of the double image of each single object on a U/B dual-exposure Schmidt photographic plate, 95 primary and 45 secondary quasar candidates were selected on the basis of their $U$ image being too bright. The spectroscopic identification of the primary candidates led to the discovery of 59 bona fide quasars (out of which 6 were previously known). The Palomar Schmidt plate was digitised using the MAMA measuring machine and the outcoming data reduced using ad hoc procedures. A photometric calibration allowed us to derive values for the limiting magnitudes and for the U-B index selection threshold of the survey. A catalogue containing 60 quasars is presented with accurate positions, magnitudes and additional information such as redshifts. We studied the spatial distribution of the objects and detected, for the quasars of our sample, a significant deviation from randomness in the form of a propensity to cluster in pairs on the celestial sphere with a typical scale of about 10 arcmin. We also formally detected a tendency towards a 3-D clustering, but this result is induced by a single pair of quasars. A forthcoming paper will deal with a similar work performed in a field around NGC 520; the latter field is located directly to the North of the present one and slightly overlaps it. Based on observations acquired at the Mount Palomar and Las Campanas Observatories as well as at the European Southern Observatory. Also based on Schmidt-plate digitisations performed with the MAMA measuring machine of C.A.I. (I.N.S.U., Paris). [less ▲]

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See detailSur la pratique de la localisation implicite dans le Dictionnaire de l'Ouest-wallon d'Arille Carlier
Boutier, Marie-Guy ULg

in Travaux de linguistique et de philologie (1997), 35-36

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See detailUretero-arterial fistula: two observations.
VAN DAMME, Hendrik ULg; KEPPENNE, Véronique ULg; SakalihasanN, Natzi ULg et al

in Acta Chirurgica Belgica (1997), 97(3), 133-6

Two cases of life-threatening haematuria, secondary to an uretero-arterial fistula, are reported. Both cases present predisposing causative factors. One patient had a combination of previous aorto ... [more ▼]

Two cases of life-threatening haematuria, secondary to an uretero-arterial fistula, are reported. Both cases present predisposing causative factors. One patient had a combination of previous aorto-bifemoral bypass grafting, an iliac artery aneurysm (retrogradely perfused), and an indwelling ureteral stent for ureteral compression. The other patient had previous aortoiliac surgery and obstructive uropathy with chronic urinary tract infection. Preoperative diagnosis of uretero-arterial fistula was made in only one patient. He was successfully operated (exclusion of the iliac aneurysm). In the other patient, nephrectomy was attempted to control reno-ureteral bleeding of unknown origin. Fatal recidive of brisk haematuria occurred some days later. Factors contributing to the development of uretero-arterial fistula, their diagnosis and optimal treatment are discussed. [less ▲]

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See detailGluonic content of the scalar meson nonet in a scaled effective Lagrangian
Jaminon, Martine ULg; Van den Bossche, Bruno

in Nuclear Physics A (1997), 619

A scaled SU(3) Nambu-Jona-Lasinio Lagrangian is used to compute the mass of the nine scalar mesons in the vacuum and the mass of the glueball. This chiral model provides a gluonic content to the scalar ... [more ▼]

A scaled SU(3) Nambu-Jona-Lasinio Lagrangian is used to compute the mass of the nine scalar mesons in the vacuum and the mass of the glueball. This chiral model provides a gluonic content to the scalar mesons as well as a quark content to the glueball. It is shown that a suitable choice of the vacuum gluon condensate allows reproduction of the experimental masses of the scalar mesons except for K*0(1430). This choice corresponds to a weak coupling between the gluon and quark condensates, giving f0(1500) or fJ(1710) which is nearly a pure glueball. [less ▲]

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See detailParathyroid Hormone in the Treatment of Involutional Osteoporosis: Back to the Future
Reginster, Jean-Yves ULg; Taquet, A. N.; Fraikin, G. et al

in Osteoporosis International (1997), 7(Suppl 3), 163-8

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See detailLa contestation des pierres. Des œuvres écrites d'Olivier Smolders
Badir, Sémir ULg

in Textyles : Revue des Lettres Belges de Langue Française (1997), 14

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See detailPlasma bovine pregnancy-associated glycoprotein concentrations throughout gestation in relationship fetal number in the cow
Patel, Osman V; Sulon, Joseph ULg; Beckers, Jean-François ULg et al

in European Journal of Endocrinology (1997), 137

This study characterized the peripheral plasma bovine pregnancy-associated glycoprotein (bPAG) profile throughout gestation and examined the effect of stage of gestation and fetal number on this profile ... [more ▼]

This study characterized the peripheral plasma bovine pregnancy-associated glycoprotein (bPAG) profile throughout gestation and examined the effect of stage of gestation and fetal number on this profile in Holstein cows after non-surgical embryo transfer. Cows (n = 12) were divided into three groups: group 1 = normal singleton pregnancies (n = 5); group 2 = normal twin pregnancies (n = 5); group 3 = abnormal twin pregnancies (n = 2). Blood was collected about every third day from day 0 (defined as the first day of standing estrus), then daily for the last 10 days of gestation, and sampling was stopped one day postpartum. The time-related changes in plasma bPAG concentrations were significantly (P < 0.01) affected by the stage of gestation and fetal number (P < 0.01), except during the last 10 days of gestation. In both normal pregnancy groups, bPAG concentration increased rapidly during the first trimester (0.5 +/- 0.1 to 14.6 +/- 1.7 ng/ml and 1.0 +/- 0.6 to 21.8 +/- 4.8 ng/ml, in singleton and twin-bearing groups respectively), then progressively between days 160 and 20 prepartum (31.6 +/- 6.2 to 114.3 +/- 31.3 ng/ml and 41.6 +/- 7.4 to 155.8 +/- 36.6 ng/ml in singleton and twin-bearing cows respectively). The mean concentration between days 20 and 10 prepartum approximately tripled (P < 0.001) in both these groups of cows (114.3 +/- 31.1 to 493.0 +/- 75.3 ng/ml and 155.8 +/- 36.6 to 409.3 +/- 114.7 ng/ml in singleton and twin-bearing cows respectively), but between days 10 prepartum and parturition the values increased about threefold (P < 0.01) in the singleton group (493.0 +/- 75.3 to 1352.8 +/- 286.5 ng/ml) and fivefold (P < 0.001) in the twin-bearing group (409.3 +/- 114.7 to 2154.0 +/- 505.7 ng/ml). The two cows in group 3 that gave birth prematurely to a stillborn calf or to a schistosomus reflexus calf exhibited an aberrant bPAG profile. Our results indicate that peripheral bPAG concentrations are correlated to the stage of gestation and fetal number, and that the profile of the peripheral plasma concentrations provides a useful indication of the feto-placental status. [less ▲]

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See detailEstimation des dégâts de cervidés en pessière wallonne : Une application ciblée de l'inventaire régional
Rondeux, Jacques ULg; Lecomte, Hugues

in Forêt Wallonne (1997), (31), 6-9

Au sein des régions forestières comprises dans la zone d'extension du cerf (Cervus elaphus L.) en Wallonie, les dégâts dûs aux écorcements et aux frottures comptent parmi les tares les plus graves qui ... [more ▼]

Au sein des régions forestières comprises dans la zone d'extension du cerf (Cervus elaphus L.) en Wallonie, les dégâts dûs aux écorcements et aux frottures comptent parmi les tares les plus graves qui peuvent affecter un peuplement, qu'il s'agisse de son potentiel de régénération ou de la qualité du bois produit. Peu d'informations chiffrées relatives à ces dégâts existent à une échelle autre que celle de massifs ou de propriétés. La récente mise en oeuvre méthodologique de l'inventaire forestier wallon permanent basé sur un échantillonnage systématique a prévu, à l'instar d'autres inventaires réalisés en Europe, la récolte d'informations non seulement relatives au matériel ligneux et à son évolution au cours du temps mais aussi à d'autres applications. L'étude qui suit propose une méthode d'investigation des dégâts de cervidés sur l'ensemble des pessières de la forêt wallonne. Elle ne vise en aucune manière à porter un jugement sur l'équilibre "forêt-gibier" mais son objectif est, dans une large mesure, de montrer comment il est possible de préciser la nature et l'importance des dégâts encourus et de proposer ainsi une alternative aux approximations visuelles sommaires fournies à des échelles locales et non extrapolables, sous peine de devoir recourir à des hypothèses irréalistes. Après avoir défini l'opportunité même de l'étude, nous rappellerons brièvement quelques aspects méthodologiques de l'inventaire, nous en envisagerons ensuite le type de données récoltées en matière de dégâts occasionnés aux arbres, ainsi que les modalités de traitement et d'exploitation de celles-ci. Nous proposerons enfin une application concrète de la technique d'investigation aux pessières de la Région wallonne, avant de tirer quelques conclusions générales. [less ▲]

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See detailBiochemical aspects of almond microcuttings related to in vitro rooting ability
Caboni, E.; Tonelli, M. G.; Lauri, P. et al

in Biologia Plantarum (1997), 39(1), 91-97

Microcuttings of seven genotypes of almond (Prunus dulcis Mill) used as peach rootstocks, showed different rooting ability in vitro. No direct relationship was found between peroxidase activity and total ... [more ▼]

Microcuttings of seven genotypes of almond (Prunus dulcis Mill) used as peach rootstocks, showed different rooting ability in vitro. No direct relationship was found between peroxidase activity and total phenol content, determined in the whole microcuttings prior to the root inducing treatment, and the rooting ability of these genotypes. However, a positive relationship was found between free indole-3-acetic acid (IAA) level and IAA-aspartate and the rooting response. After transferring into the rooting medium, peroxidase activity of the easiest-to-root genotype increase up to a peak and then declined and the total phenol content showed an opposite trend. These variations did not occur in the most difficult-to-root genotype. [less ▲]

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See detailSite-directed mutagenesis of glutamate 166 in two beta-lactamases. Kinetic and molecular modeling studies.
Guillaume, Gilliane; Vanhove, M; Lamotte-Brasseur, J et al

in Journal of Biological Chemistry (1997), 272(9), 5438-44

The catalytic pathway of class A beta-lactamases involves an acyl-enzyme intermediate where the substrate is ester-linked to the Ser-70 residue. Glu-166 and Lys-73 have been proposed as candidates for the ... [more ▼]

The catalytic pathway of class A beta-lactamases involves an acyl-enzyme intermediate where the substrate is ester-linked to the Ser-70 residue. Glu-166 and Lys-73 have been proposed as candidates for the role of general base in the activation of the serine OH group. The replacement of Glu-166 by an asparagine in the TEM-1 and by a histidine in the Streptomyces albus G beta-lactamases yielded enzymes forming stable acyl-enzymes with beta-lactam antibiotics. Although acylation of the modified proteins by benzylpenicillin remained relatively fast, it was significantly impaired when compared to that observed with the wild-type enzyme. Moreover, the E166N substitution resulted in a spectacular modification of the substrate profile much larger than that described for other mutations of Omega-loop residues. Molecular modeling studies indicate that the displacement of the catalytic water molecule can be related to this observation. These results confirm the crucial roles of Glu-166 and of the "catalytic" water molecule in both the acylation and the deacylation processes. [less ▲]

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See detailProduction and activation of matrix metalloprotease-9 (MMP-9) by HL-60 promyelocytic leukemia cells
Devy, L.; Noël, Agnès ULg; Baramova, E. et al

in Biochemical and Biophysical Research Communications (1997), 238

Human promyelocytic HL-60 cells have been used as a model of acute leukemia to investigate the expression and the regulation of matrix metalloproteases (MMPs), known to contribute to the degradation of ... [more ▼]

Human promyelocytic HL-60 cells have been used as a model of acute leukemia to investigate the expression and the regulation of matrix metalloproteases (MMPs), known to contribute to the degradation of extracellular matrix components. As shown by gelatin zymography, HL-60 cells constitutively released significant amounts of proMMP-9 (92 kDa) and moderate amounts of proMMP-2 (72 kDa). Furthermore, casein zymography confirmed the presence of serine proteases in the form of pro-urokinase. Activation of proMMP-9 was dependent on the plasminogen activator/plasmin (PA/plasmin) system and was inhibited by aprotinin. MMP-9 was only detected in cellular extracts or conditioned media incubated with HL-60 cells, indicating that cells are essential to the activation process. Addition of plasminogen increased by 3-fold the basal invasive rate of these cells across a matrigel layer (2.1%versus0.7% in control cells after 4 h of incubation). Taken together, these results indicate that HL-60 cells exhibit an autocrine activation mechanism of proMMP-9 via the PA/plasmin system and that activation of proMMP-9 increases their invasive potential [less ▲]

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See detailLangmuir film balance study of the surface properties of a soluble fraction of milk fat-globule membrane
Innocente, N.; Blecker, Christophe ULg; Deroanne, C. et al

in Journal of Agricultural and Food Chemistry (1997), 45(5), 1559-1563

Viewed from its origin, composition, and physicochemical properties, milk fat-globule membrane (MFGM) appears to act as a good, natural emulsifier and should be also considered as a potential stabilizing ... [more ▼]

Viewed from its origin, composition, and physicochemical properties, milk fat-globule membrane (MFGM) appears to act as a good, natural emulsifier and should be also considered as a potential stabilizing agent in the preparation of certain foods, e.g. creams and emulsions, infant formulas, and reduced-fat products. The present work was undertaken in an attempt to gain further information on the physicochemical properties of MFGM. In particular, the purpose of this study was to determine surface properties of a soluble fraction of MFGM (SFMFGM) using a film balance and to investigate the changes in the surface activity at different temperatures, which may occur during milk cream ripening or during heat and mechanical treatments of dairy products. The results showed that film balance measurements at the air/water interface actually provided a useful method for the study of SFMFGM monolayers. It was deduced from the compression isotherms that the SFMFGM films spread at the air/water interface presented a different behavior when the temperature varied from 4 to 40 degrees C. [less ▲]

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See detailTrace metal transfers between water and sediment in a freshwater system. Influence of microbial activity
Hambuckers-Berhin, Françoise; Hambuckers, Alain ULg; Remacle, Jean

in Studies in Environmental Science (1997), 68(353-368),

The purpose of our work was to determine, in a freshwater batch system, the importance and the direction of trace metal transfers between sediment and water as influenced by bacterial activity. Sediment ... [more ▼]

The purpose of our work was to determine, in a freshwater batch system, the importance and the direction of trace metal transfers between sediment and water as influenced by bacterial activity. Sediment was incubated in Meuse water in different conditions. Net transfer occurred on an average from sediment to water for Co, Cs, Cr, Cu, Hg, La, Ni, Zn and from water to sediment for Bi, Cd, Pb, Sb, Tl. Positive correlations between oxygen consumption and transfer of nine metals from sediment to water demonstrate the influence of bacterial activity. Correlations of the metal transfer either with water pH or with the variation of sediment weight at the end of incubation led to suppose that the alteration of the chemical conditions also strongly influenced the transfers. It was confirmed by the comparison of chemical characteristics of the water and of the sediment at the end of incubation in contrasted conditions. The uptake of 12 metals by a bacterial community isolated from the sediment was related to metal concentrations in the water. The specific transfer from the water to the bacterial biomass was appraised in the sediment incubation experiments. It allowed to compute the net metal transfer of 12 metals from the sediment to the water with significant bacterial activity. The comparison of these values with the transfers occurring at 4°C, i.e. with reduced bacterial activity, demonstrated that the transfer of 11 metals from the sediment to the water is clearly enhanced by bacterial activity. [less ▲]

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See detailContribution à l'étude de la flore et de l'écologie des plantes de quelques grottes wallonnes.
Garbacki, Nancy ULg

in Bulletin des Chercheurs de la Wallonie (1997), XXXVI

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See detailFluidothérapie parentérale pratique chez les bovins
Rollin, Frédéric ULg

in Annales de Médecine Vétérinaire (1997), 141(2), 89-111

After setting up the main indications for parenteral fluid therapy in calves and adult cattle, the means are studied to practically evaluate on the field the dehydration, acid-base status, electrolyte ... [more ▼]

After setting up the main indications for parenteral fluid therapy in calves and adult cattle, the means are studied to practically evaluate on the field the dehydration, acid-base status, electrolyte disturbances and glycemia. The various classes of fluids are then considered as a function of the indications. Use of transfusion, hypertonic solutions and parenteral nutrition is broached. Routes and techniques of fluid administration are detailed. Obstacles encountered by the bovine practitioner when using parenteral fluid therapy are emphasized just as the means to overcome them. In this regard, it is described how to correctly prepare fluids for suited parenteral use in cattle. In fact, the present laws do not given this allowance to the practitioners. However, in most cases, it constitutes the only economical option avoiding worthless sufferings and death of the animal. [less ▲]

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See detailRadiative Lifetimes for the 4p Excited States of Phosphorus and the Oscillator Strengths of Solar Lines
Berzinsh, U.; Svanberg, S.; Biémont, Emile ULg

in Astronomy and Astrophysics (1997), 326

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See detailFunctional anatomy of verbal and visuospatial span tasks in Alzheimer's disease
Collette, Fabienne ULg; Salmon, Eric ULg; Van der Linden, Martial ULg et al

in Human Brain Mapping (1997), 5(2), 110-118

The aim of the study was to emphasize cerebral regions which subserve the performance of short-term memory tasks in patients with Alzheimer's disease. We correlated scores obtained on span tasks with ... [more ▼]

The aim of the study was to emphasize cerebral regions which subserve the performance of short-term memory tasks in patients with Alzheimer's disease. We correlated scores obtained on span tasks with cerebral metabolism measured at rest with positron emission tomography. Scores obtained on the digit span task correlated with glucose metabolism in a brain area centered on the premotor cortex and extending to the adjacent motor and parietal gyri. There exists some evidence suggesting that this area may subserve the sequential organization of material stored in short-term memory. In a secondary analysis, we also observed significant interregional correlations between left-sided brain areas which are part of the neural network subserving verbal working memory processes in healthy controls. These data suggest that individual performance on verbal span tasks in AD patients may essentially depend on the preservation of their ordination processing capacity. The absence of correlation with prefrontal regions suggests that AD patients might not spontaneously engage central executive resources to reach their maximal span score. For simultaneous visuospatial span task, the performance of patients correlated with posterior brain regions, and not with prefrontal cortices. Hum. Brain Mapping 5:110-118, 1997. © 1997 Wiley-Liss Inc. [less ▲]

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