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See detailA magnetic and conversion electron Mossbauer spectral study of amorphous Dy20Fe80-yCoy thin films
Fleury-Frenette, Karl ULg; Delwiche, Jacques ULg; Grandjean, Fernande ULg et al

in IEEE Transactions on Magnetics (2001), 37(4), 2311-2314

Amorphous thin films of Dy20Fe80-yCoy, with 0 < y < 20 and of ca. 40 nm thickness, have been prepared by sputtering on polyimide substrates. The 295 K conversion electron Mossbauer spectra (CEMS) of these ... [more ▼]

Amorphous thin films of Dy20Fe80-yCoy, with 0 < y < 20 and of ca. 40 nm thickness, have been prepared by sputtering on polyimide substrates. The 295 K conversion electron Mossbauer spectra (CEMS) of these films consist of broadened sextets which have been analyzed with a distribution of hyperfine fields in which the iron moments are oriented perpendicular to the plane of the film, an orientation which is in agreement with the perpendicular magnetic anisotropy observed herein at 295 K by vibrating sample magnetrometry. The average hyperfine field and isomer shift increase linearly with increasing Co content. Both increases arise from an increase in the electron occupation of the 3d states as the cobalt content increases. [less ▲]

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See detailDynamics of copepod faecal pellets in relation to a Phaeocystis dominated phytoplankton bloom: characteristics, production and flux
Frangoulis, Costa; Belkhiria, Sami; Goffart, Anne ULg et al

in Journal of Plankton Research (2001), 23(1), 75-88

Copepod faecal pellet characteristics and production were measured in spring 1995, 1996 and 1997 in the North Sea Southern Bight in order to define changes due to the development of the phytoplankton ... [more ▼]

Copepod faecal pellet characteristics and production were measured in spring 1995, 1996 and 1997 in the North Sea Southern Bight in order to define changes due to the development of the phytoplankton bloom. Changes were related to the succession from diatoms to a Phaeocystis sp. bloom. Mean monthly pellet production decreased during the Phaeocystis bloom development to 0.27 pellets ind. –1 h –1, approximately 80% lower than before and after the bloom. Although phytoplanktonic pigments showed significant differences between inshore and offshore stations, there was no such significant difference for faecal pellet production. Faecal pellet sinking-rate decreased from 100 to 70 m day –1 during the transition from a diatom- to a Phaeocystis-dominated bloom. This was due to a decrease in pellet density and/or a decrease of the pellet volume. These results supported the idea of lower feeding of copepods under Phaeocystis bloom conditions. As mean seasonal density of copepod faecal pellets was higher (1.37 g cm –3) than in other seas, accidental ingestion of sedimentary material as the cause of this high density is discussed. [less ▲]

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See detailDonnées récentes sur la pathogenèse de l'infection à Microsporum canis chez les carnivores domestiques
Brouta, F.; Descamps, F.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (2001), 145

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See detailLa marca de Marcos. ¿Pueden hablar los indígenas mexicanos ?
Vanden Berghe, Kristine ULg

in Cuadernos Americanos (2001), 87

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See detailImaging Mixed Lipid Monolayers By Dynamic Atomic Force Microscopy
Deleu, Magali ULg; Nott, Katherine ULg; Brasseur, Robert ULg et al

in Biochimica et Biophysica Acta-Biomembranes (2001), 1513(1),

Phase imaging with tapping mode atomic force microscopy (AFM) and force modulation microscopy were used to probe the mechanical properties of phase-separated lipid monolayers made of a mixture (0.25:0.75 ... [more ▼]

Phase imaging with tapping mode atomic force microscopy (AFM) and force modulation microscopy were used to probe the mechanical properties of phase-separated lipid monolayers made of a mixture (0.25:0.75) of the surface-active lipopeptide surfactin and of dipalmitoylphosphatidylcholine (DPPC). The π–A isotherms and the result of a molecular modeling study revealed a loose, 2-D liquid-like organization for the surfactin molecules and a closely packed, 2-D solid-like organization for DPPC molecules. This difference in molecular organization was responsible for a significant contrast in height, tapping mode phase and force modulation amplitude images. Phase imaging at light tapping, i.e., with a ratio of the set-point tapping amplitude with respect to the free amplitude Asp/A0≈0.9, showed larger phase shifts on the solid-like DPPC domains attributed to larger Young’s modulus. However, contrast inversion was observed for Asp/A0<0.7, suggesting that at moderate and hard tapping the image contrast was dominated by the probe–sample contact area. Surprisingly, force modulation amplitude images showed larger stiffness for the liquid-like surfactin domains, suggesting that the contrast was dominated by contact area effects rather than by Young’s modulus. These data emphasize the complex nature of the contrast mechanisms of dynamic AFM images recorded on mixed lipid monolayers. [less ▲]

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See detailEffect of the msb3 msb4 double mutation on the intracellular pool of purine nucleotides in the yeast Saccharomyces cerevisiae: application to the study of the biological activity of the oncogenic human protein oncTre210p.
Bach, Stéphane; Burny, Arsène; Bontemps, Françoise et al

in Yeast (Chichester, England) (2001), 18(S305), 17-7

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See detailVies et Miracles de Domitien Deuxième partie
George, Philippe ULg

in Analecta Bollandiana : Revue Critique d’Hagiographie = A Journal of Critical Hagiography (2001), CXIX

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See detailEffects of lesions of the medial preoptic nucleus on the testosterone-induced metabolic changes in specific brain areas in male quail
Balthazart, Jacques ULg; Stamatakis, A.; Bacola, S. et al

in Neuroscience (2001), 108(3), 447-466

The effects of bilateral lesions of the medial preoptic nucleus in association with testosterone on the metabolic activity in discrete brain regions was studied quantitatively by the in vivo ... [more ▼]

The effects of bilateral lesions of the medial preoptic nucleus in association with testosterone on the metabolic activity in discrete brain regions was studied quantitatively by the in vivo autoradiographic 2-deoxyglucose method. Adult male quail were castrated and then left without hormone replacement therapy or treated with testosterone or treated with testosterone and submitted to a bilateral lesion of the medial preoptic nucleus, a brain region that plays a key role in the activation of male copulatory behavior by testosterone. Treatment for about 10 days with testosterone activated the expression of the full range of male sexual behaviors and these behaviors were completely suppressed by the medial preoptic nucleus lesions. Mapping of 2-deoxyglucose uptake revealed both increases and decreases of metabolic activity in discrete brain regions associated with the systemic treatment with testosterone as well as with the lesion of the medial preoptic nucleus. Testosterone affected the oxidative metabolism in brain areas that are known to contain sex steroid receptors (such as the nucleus taeniae and the paraventricular and ventromedial nuclei of the hypothalamus) but also in nuclei that are believed to be devoid of such receptors. Effects of testosterone in these nuclei may be indirect or reflect changes in terminals of axons originating in steroid-sensitive areas. Bilateral medial preoptic nucleus lesions affected 2-deoxyglucose uptake in a variety of brain regions. Some of these regions are known to be mono-synaptically connected to the medial preoptic nucleus. Metabolic depression in these areas may reflect retrograde changes in the neurons projecting to the damaged field. The metabolic changes identified in the present study confirm the prominent role of the preoptic area in the control of sexual behavior, show that changes in the physiology of the visual system represent one of the ways through which testosterone influences the occurrence of this behavior and demonstrate that the medial preoptic nucleus has marked effects on the metabolic activity in a variety of limbic and telencephalic structures. This study also indicates that the medial preoptic nucleus affects the activity of the area ventralis of Tsai, a dopaminergic area known to send projections to a variety of hypothalamic, thalamic and mesencephalic nuclei that are implicated in the control of male sexual behavior. These data therefore support the notion that the control of the dopaminergic activity in the area ventralis of Tsai by the medial preoptic nucleus represents one of the ways through which the medial preoptic area regulates male reproductive behavior. (C) 2001 IBRO. Published by Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailSpectroscopic evidence for high-altitude Aurora at Jupiter from Galileo Extreme Ultraviolet Spectrometer and Hopkins Ultraviolet Telescope observations
Ajello, Joseph M.; Shemansky, D. E.; Pryor, Wayne R. et al

in Icarus: International Journal of Solar System Studies (2001), 152(1), 151-171

The Galileo Extreme Ultraviolet Spectrometer (EUVS) and the Hopkins Ultraviolet Telescope (HUT) acquired UV spectra of Jupiter Aurora in the period from 1995 through 1997, The EUVS spectra spanned the ... [more ▼]

The Galileo Extreme Ultraviolet Spectrometer (EUVS) and the Hopkins Ultraviolet Telescope (HUT) acquired UV spectra of Jupiter Aurora in the period from 1995 through 1997, The EUVS spectra spanned the wavelength range 540-1280 Angstrom and the HUT spectra measured the extreme ultraviolet and far ultraviolet (EUV + FUV) wavelength range 830-1850 Angstrom. Both sets of spectra present evidence of high-altitude, optically thin H-2 band emissions from the exobase region, The analysis of the UV spectra with a two-stream electron transport model and a jovian model auroral atmosphere indicates that the primary electron flux is composed of both soft and hard electrons with characteristic energies in the soft electron energy range of 20-200 eV and the hard electron range of 5-100 keV, The soft electron flux causes enhanced EUV emission intensities below 1100 Angstrom. The soft electron flux may explain the high temperature of the upper atmosphere above the homopause as measured from Il: rovibrational temperatures in the IR. For the deep aurora, a high primary characteristic energy above 5 keV is known to be present. The Galileo Energetic Particle Detector (EPD) has measured the electron distribution functions for energies above 15 keV in the middle magnetosphere. The high-energy distribution functions can be modeled by a combination of Maxwellian and kappa distributions. However, the EUV (800-1200 Angstrom) portion of the HUT spectrum cannot be modeled with a single distribution of hard electrons as was possible in the past for the FUV (1200-1650 Angstrom) spectrum measured by itself, The combination of EUV and FUV spectral observations by HUT serves to identify the amount of soft electron flux relative to the hard primary flux required to produce the high-altitude aurora in the neighborhood of the exobase, (C) tool academic Press. [less ▲]

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See detailMother-Young Relationships in Belgian Blue Cattle after a Caesarean Section: Characterisation and Effects of Parity
Vandenheede, Marc ULg; Nicks, Baudouin ULg; Desiron, A. et al

in Applied Animal Behaviour Science (2001), 72(3), 281-292

The systematic use of Caesarean section in "double muscled" Belgian Blue cattle can induce ethical concerns. The aims of the following study was to characterise mother-young relationships in such a ... [more ▼]

The systematic use of Caesarean section in "double muscled" Belgian Blue cattle can induce ethical concerns. The aims of the following study was to characterise mother-young relationships in such a situation and to assess the effect of parity. Fifteen heifers and 15 cows of the Belgian Blue breed were observed using video recording when isolated with their calf during the 3 days following Caesarean, a rapid surgery with rare occurrence of aggressive behaviour and no sign of cows' discomfort or weakness. All calves were bottle-fed mother's colostrum once before first suckling occurred. Heifers' calves received a supplementary number of three such artificial meals, while cows' calves needed only one. The overall median time to first licking of the calf by the mother was 3.3min without any effect of parity. The mean licking frequency was 29.2+/-15.8 per 24h: heifers licked their calf less frequently than cows, respectively 23.4+/-15.3 per 24h versus 35.1+/-14.5 per 24h (P<0.05). The mean total licking duration was 42.2+/-25.9min per 24h: there was no significant difference between heifers and cows. The overall median time to first suckling was 6.1h, without any effect of parity. The mean suckling frequency was 8.4+/-4.8 per 24h: for half of these suckling bouts, the calf was situated on the left side of the mother, i.e. the side of the scar. The suckling frequency was negatively correlated with the number of artificial meals (r(s)=-0.45,P<0.05). Heifers suckled their calf less often than cows, respectively 6.1+/-3.1 per 24h versus 10.7+/-5.2 per 24h (P<0.01), but the left side proportion was not significantly different. The mean suckling total duration was 35.3+/-21.0min per 24h. The calf was on the left side of the mother during half of this time. Heifers suckled their calf during a shorter time than cows, respectively 26.9+/-20.0min per 24h versus 43.8+/-19.1min per 24h (P<0.05), and the left side proportion was not significantly different. Licking frequency and suckling duration were positively correlated (r=0.43,P<0.05). Only 10% of the mothers (one heifer and two cows) butted their calf and kicking was never observed. Despite the difficult comparison with results of the literature according to various methodologies, mother-young relationships were considered as similar to those reported after natural calving. In our study, cows can be considered as better mothers than heifers. [less ▲]

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See detailPrésentation
Badir, Sémir ULg; Arrivé, Michel

in Linx (2001), 44

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See detailCarbon sinks in temperate forests
Martin, Philippe; Nabuurs, G. J.; Aubinet, Marc ULg et al

in Annual Review of Energy & the Environment (2001), 26

In addition to being scientifically exciting, commercially important, and environmentally essential, temperate forests have also become a key diplomatic item in international climate negotiations as ... [more ▼]

In addition to being scientifically exciting, commercially important, and environmentally essential, temperate forests have also become a key diplomatic item in international climate negotiations as potential sinks for carbon. This review presents the methods used to estimate carbon sequestration, identifies the constraints and opportunities for carbon sequestration in temperate forests, addresses the issues raised by the monitoring of carbon sequestration, and analyzes uncertainties pertaining to the sequestration of carbon by temperate forests. This review serves a dual purpose: It aims at informing policy makers about carbon sequestration in temperate forests and at making forest ecologists, biogeochemists, and atmospheric scientists aware of the structure of an international agreement to reduce CO2 and other greenhouse gas emissions and some of the real, still answered scientific questions that it poses. [less ▲]

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See detailPharma clinics le medicament du mois. Le nebivolol (Nobiten).
Scheen, André ULg

in Revue Médicale de Liège (2001), 56(11), 788-91

Nebivolol (Nobiten, Menarini) is a new beta-blocker recommended for the management of essential hypertension, at a dose of 5 mg once daily. It is administered as a racemic mixture of equal proportions of ... [more ▼]

Nebivolol (Nobiten, Menarini) is a new beta-blocker recommended for the management of essential hypertension, at a dose of 5 mg once daily. It is administered as a racemic mixture of equal proportions of d- and l-enantiomers. As a lipophilic agent, it is metabolised in the liver and transformed in several active metabolites, essentially via the CYP 2D6, an isoform of cytochrome P450 characterized by a genetic polymorphism. Nebivolol is highly specific for beta-1 adrenergic receptors; it is devoid of intrinsic sympathomimetic or membrane stabilising activity. Interestingly enough, it appears to have nitric oxide-mediated vasodilatory effects which might explain its favourable haemodynamic profile. Several comparative trials demonstrated an antihypertensive activity that was similar or slightly superior to that observed with various other reference antihypertensive agents. Nebivolol has an additive antihypertensive effect in combination with hydrochlorothiazide. All studies reported that the drug has a good clinical and biological tolerance profile. Therefore, nebivolol may be recommended as an alternative first-line treatment option for the management of patients with mild to moderate essential hypertension. [less ▲]

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See detailMagnetic properties of magnetically textured Bi-2212 ceramics
Vanderbemden, Philippe ULg; Bougrine, Hassan ULg; Ausloos, Marcel ULg et al

in Physica C: Superconductivity (2001), 351(1), 67-70

This paper aims at reporting magnetic properties of bulk polycrystalline Bi2Sr2Ca0.8Dy0.2Cu2O8-y samples textured under a magnetic field. The microstructure of these materials is highly anisotropic and ... [more ▼]

This paper aims at reporting magnetic properties of bulk polycrystalline Bi2Sr2Ca0.8Dy0.2Cu2O8-y samples textured under a magnetic field. The microstructure of these materials is highly anisotropic and exhibits particular features needed to be taken into account in order to interpret their magnetic and electrical properties. First the AC magnetic susceptibility has been measured for several magnetic fields (H parallel to ab and H parallel to c) and compared to the electrical resistivity data. The structure of the chi'' peak is shown to be related to the chemical content distribution of the superconducting grains. Next, the magnetic flux profiles have been extracted from the magnetic measurements using the Campbell-Rollins procedure. The anisotropy of the flux profiles and their peculiar curvature behaviour for H parallel toc point out the role of both grain platelet structure and the presence of secondary phases. From these results, we conclude that the magnetic properties of such magnetically textured materials do not allow for a reliable extraction of the critical current density J(c) but essentially probe geometric effects. Such effects have to be taken into account for improving the manufacture of attractive high-T-c materials. (C) 2001 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailProthèses péniennes : taille du pénis implanté et dimensions de la virilité
Kempeneers, Philippe ULg; Andrianne, Robert ULg; Mormont, Christian ULg et al

in Cahiers de Sexologie Clinique (2001), 27(149), 18-27

The implantation of a penile prosthesis frequently results in a reduction of the erectile length compared with natural erections. Some patients complain about this fact and their satisfaction at ... [more ▼]

The implantation of a penile prosthesis frequently results in a reduction of the erectile length compared with natural erections. Some patients complain about this fact and their satisfaction at prosthesis assisted sexuality is significantly diminished. Obviously, the degree of complaint is not proportional to the objective degree of penile reduction. For an objective reality to lead to complaints, subjective criteria of appreciation have to intervene. A survey questionnaire completed by 39 implanted patients and 30 partners shows that complaints about the size of the implanted penis are mostly related to a social representation of sexuality which associates the male erotic value to criteria of erectile length, spontaneity and “naturalness”. This representation also tends to be projected in the partner’s mind, independently of her actual attitudes and feelings. Therefore, the injurious impact of penile reduction on satisfaction at the prosthetic device seems to be inseparable from a global representation of prosthetic sexuality which is experienced as a “parodic”, “reduced” virility. The reduced size of the penis focuses feelings of vexation which cannot be reduced to simple functional considerations, it embodies the painful and complex image of a lost virility. From this point of view, psychosexological counselling would be indicated in order to help some couples to improve their adaptation to penile prosthesis. Moreover, an Attitude scale towards Penile Implant (API) derived from the survey questionnaire might enable the identification of risk-patients. [less ▲]

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See detailL'élevage du "mouton de case" : aspects techniques, socio-économiques et perspectives d'amélioration au Yatenga (Burkina Faso)
Hamidou, B.; Ilboudo, J.-B.; Ouedraogo, M. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2001), 5(4), 201-208

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See detailNouvelles approches thérapeutiques puor l'hypernéphrome métastasique
Sylvestre, Rose-Marie; Jerusalem, Guy ULg; Sautois, Brieuc ULg et al

in Médecine et Hygiène (2001), 59

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See detailSémiologie cardiaque dans l’espèce équine. 1- L’anamnèse et l’examen clinique.
Amory, Hélène ULg

in Pratique Vétérinaire Equine (2001), 33

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See detailSulle tracce degli Antegnati, maestri organari
Bugini, Mariaelena ULg

in I Quaderni della Fondazione Ugo da Como (2001)

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See detailNovel inhibitors of the sodium-calcium exchanger: benzene ring analogues of N-guanidino substituted amiloride derivatives
Rogister, F.; Laeckmann, D.; Plasman, P.-O. et al

in European Journal of Medicinal Chemistry (2001), 36

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See detailA 4-year study of the mycological aspects of Kashin-Beck disease in Tibet
Chasseur, Camille; Suetens, Carl; Michel, Valérie et al

in International Orthopaedics (2001), 25

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See detailRevenant & exorcisme à Liège. Quête de reliques en Sardaigne (1634-1652)
George, Philippe ULg

in Bulletin de la Commission Royale d'Histoire (2001), CLXVII

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See detailOriginal 2-alkylamino-6-halogenoquinazolin-4(3H)-ones and KATP channel activity
Somers, F.; Ouedraogo, R.; Antoine, M.-H. et al

in Journal of Medicinal Chemistry (2001), 44

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See detailQuasar pairs with arcminute angular separations
Zhdanov, V. I.; Surdej, Jean ULg

in Astronomy and Astrophysics (2001), 372

We use the Véron-Cetty & Véron (\cite {veron}) catalog (VV) of 13 213 quasars to investigate their possible physical grouping over angular scales 10arcsec <=Delta theta <= 1000arcsec . We first estimate ... [more ▼]

We use the Véron-Cetty & Véron (\cite {veron}) catalog (VV) of 13 213 quasars to investigate their possible physical grouping over angular scales 10arcsec <=Delta theta <= 1000arcsec . We first estimate the number of quasar pairs that would be expected in VV assuming a random distribution for the quasar positions and taking into account observational selection effects affecting heterogeneous catalogs. We find in VV a statistically significant (>3sigma ) excess of pairs of quasars with similar redshifts (Delta z<= 0.01) and angular separations in the 50arcsec -100arcsec range, corresponding to projected linear separations (0.2-0.5) Mpc/h[SUB]75[/SUB] (Omega[SUB]M[/SUB] =1, Omega[SUB]Lambda[/SUB] =0) or (0.4-0.7) Mpc/h[SUB]75[/SUB] (Omega[SUB]M[/SUB] =0.3, Omega[SUB]Lambda[/SUB] = 0.7). There is also some excess in the 100arcsec -600arcsec range corresponding to (1-5) Mpc in projected linear separations. If most of these quasar pairs do indeed belong to large physical entities, these separations must represent the inner scales of huge mass concentrations (cf. galaxy clusters or superclusters) at high redshifts; but it is not excluded that some of the pairs may actually consist of multiple quasar images produced by gravitational lensing. Of course, a fraction of these pairs could also arise due to random projections of quasars on the sky. The list of 11 pairs of quasars with redshift differences Delta z<= 0.02 and angular separations 50arcsec <= Delta theta <= 100arcsec is presented in order to stimulate further observational studies and to better understand the astrophysical and cosmological significance of these interesting objects. [less ▲]

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See detailProtein adsorption on preadsorbed polyampholytic monolayers
Mahltig, Boris; Werner, Carsten; Müller, Martin et al

in Journal of Biomaterials Science. Polymer Edition (2001), 12(9), 995-1010

The adsorption behaviour of five different globular proteins on pure silicon substrates and on preadsorbed polyampholytic monolayers has been investigated as a function of protein concentration. The ... [more ▼]

The adsorption behaviour of five different globular proteins on pure silicon substrates and on preadsorbed polyampholytic monolayers has been investigated as a function of protein concentration. The prelayers were prepared by adsorption of the ampholytic diblock copolymer poly(methacrylic acid)-block-poly ((dimethylamino)ethyl methacrylate) (PMAA-b-PDMAEMA). This polyampholyte adsorbs in densely packed micelles directly from aqueous solution. Ellipsometry was used to determine the amount of adsorbed polyampholyte and protein. While ATR-IR spectroscopy gives information about the adsorption and desorption behaviour of the preadsorbed polyampholytic layer, the lateral structures of the dried films were investigated by scanning force microscopy (SFM). The amount of protein adsorbed was found to be strongly influenced by the preadsorbed polyampholyte compared to the adsorption on the pure silicon substrates. No displacement of the polyampholyte by the proteins was detected. In most cases the protein adsorption was reduced by the preadsorbed polyampholytic layer. The observed trends are explained by the change in electrostatic and hydrophilic characteristics of the substrates. Furthermore, the entropy of adsorption has to be taken into account. [less ▲]

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See detailA world monograph of the lichen genus Gyalectidium (Gomphillaceae)
Ferraro, Lidia Itati; Lücking, Robert; Sérusiaux, Emmanuël ULg

in Botanical Journal of the Linnean Society (2001), 137

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See detailPre-and post-harvest application of antagonistic yeasts for the control of gray and blue mold: efficacy and monitoring
De Clercq, D.; Dickburt, C.; Lepoivre, Philippe ULg et al

in Phytopathology (2001), 91(6), 21

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See detailShort-term variations of the partial pressure of CO2 in surface waters of the Galician upwelling system
Borges, Alberto ULg; Frankignoulle, Michel

in Progress in Oceanography (2001), 50(2-4), 283-302

The partial pressure of CO2 (pCO2) and dissolved oxygen saturation level (%O2) were monitored continuously during a cruise in August 1998, which sampled surface waters off the Galician coast. Data are ... [more ▼]

The partial pressure of CO2 (pCO2) and dissolved oxygen saturation level (%O2) were monitored continuously during a cruise in August 1998, which sampled surface waters off the Galician coast. Data are presented from two Lagrangian experiments carried out in an upwelling on the continental shelf and in the core of an offshore filament. The data show that daily variations in surface pCO2 and oxygen (%O2) were controlled by the diurnal cycle of primary production/respiration, temperature variations and air–sea exchange. Data obtained during various cross-shelf and cross-filament transects are also discussed and give an insight into the processes controlling large scale variations of pCO2 and %O2 in the Galician upwelling system. These data suggest that upwelling filaments are an important feature of the inorganic carbon cycle of upwelling systems. However more field data in the various eastern boundary current systems worldwide are needed. [less ▲]

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See detailLa libre circulation des personnes dans l'Union européenne (1er janvier - 31 décembre 2000)
Carlier, Jean-Yves ULg

in Journal de Droit Européen [=JDE] (2001), 9(3), 65-73

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See detailLe domicile : une notion plurielle
d'Huart, Véronique ULg

in Répertoire notarial (2001), VII

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See detailIgE-mediated anaphylaxis after first intravenous infusion of cyclosporine.
Ebo, D. G.; Piel, Géraldine ULg; Conraads, V. et al

in Annals of Allergy, Asthma & Immunology (2001), 87(3), 243-5

BACKGROUND: Intravenous administration of cyclosporine, which contains Cremophor EL (a polyethoxylated castor oil; BASF, Berlin, Germany), has occasionally resulted in an anaphylactic reaction. An ... [more ▼]

BACKGROUND: Intravenous administration of cyclosporine, which contains Cremophor EL (a polyethoxylated castor oil; BASF, Berlin, Germany), has occasionally resulted in an anaphylactic reaction. An apparent hypersensitivity reaction (bronchospasm and decrease in blood pressure) had occurred during heart transplantation in a 59-year-old woman after intravenous infusion of cyclosporine. Subsequent oral administration of cyclosporine precipitated no reaction. OBJECTIVE: The purpose of this study was to attempt to ascertain the mechanism responsible for the anaphylactic reaction. METHODS: Hypersensitivity investigations, including total serum IgE and allergen-specific IgE quantifications, skin testing, and basophil activation tests by flow cytometric determination of CD63 upregulation were undertaken in the study patient and in two healthy control subjects who were free of medication. RESULTS: The results of intradermal testing with Cremophor EL were positive after 15 minutes in the study patient only. Both cyclosporine and Cremophor EL induced considerable activation of the basophils from our study patient, with an upregulation of CD63 expression from 1% to 39% and 55%, respectively. In contrast, the expression of CD63 on basophils from the two control subjects remained essentially unchanged. CONCLUSIONS: The negative investigative findings in the control subjects, the patient's clinical manifestations in temporal relationship to the infusion, her positive results on intradermal testing with Cremophor, the basophil activation test results, and her uneventful course after oral administration of cyclosporine strongly support the presence of IgE antibodies to Cremophor EL in our patient. [less ▲]

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See detailFactors affecting hematopoietic recovery after autologous peripheral blood progenitof-cell transplantation in aggressive non-Hodgkin's lymphoma : a prospective study of 123 patients
Langouet, Anne-Marie; Brice, Pauline; Simon, Danielle et al

in Hematology Journal : The Official Journal of the European Haematology Association (2001), 2

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See detailUne enquête internationale sur l'éducation à la citoyenneté : Connaissances, représentations, attitudes et engagement des jeunes
Lafontaine, Annette ULg; Hindryckx, Geneviève ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 59-64

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See detailNote sous corr., Bruxelles du 27 juin 2001 (affaire de la Crèche Clovis)
Jacobs, Ann ULg

in Journal des Procès (2001), (419), 30-31

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See detailCompetition between deep impurity and dopant behavior of Mg in GaN Schottky diodes
Schmeits, Marcel; Nguyen, Ngoc Duy ULg; Germain, Marianne

in Journal of Applied Physics (2001), 89

The effect of the deep acceptor Mg on the electrical characteristics of p-doped GaN Schottky diodes is analyzed. The theoretical study is based on the numerical resolution of the basic semiconductor ... [more ▼]

The effect of the deep acceptor Mg on the electrical characteristics of p-doped GaN Schottky diodes is analyzed. The theoretical study is based on the numerical resolution of the basic semiconductor equations, including the continuity equation for the Mg-related acceptor level. It gives the steady-state and small-signal analysis of p-doped GaN:Mg Schottky diodes, yielding as final result the frequency dependent capacitance and conductance of the structure. It is shown that the low-frequency characteristics are determined by the carrier exchange between the Mg related impurity level and the valence band, whereas above the impurity transition frequency, the hole modulation of the depletion layer edge governs the electrical response. Detailed results are shown on the effect of temperature, applied steady-state voltage and series resistance. The study of two back-to-back connected GaN Schottky diodes reveals the appearance of typical features in the electrical characteristics, depending on the respective Schottky barrier height of the two junctions. [less ▲]

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See detailEffets comportementaux et neurochimiques de stimuli associés à l’administration d'éthanol: implications pour les comportements d'alcoolisation
Quertemont, Etienne ULg; De Witte, Philippe

in Cahiers de l'I.R.E.B. (2001), 15

Les drogues, y compris l’alcool, peuvent servir de stimuli inconditionnels dans des situations d’apprentissage par conditionnement. Les stimuli environnementaux qui accompagnent systématiquement ... [more ▼]

Les drogues, y compris l’alcool, peuvent servir de stimuli inconditionnels dans des situations d’apprentissage par conditionnement. Les stimuli environnementaux qui accompagnent systématiquement l’administration d’alcool peuvent ainsi acquérir le statut de stimuli conditionnés capables d’induire à eux seuls des réactions physiologiques conditionnées. Deux types de réactions conditionnées avec l’alcool ont été observées. D’une part, les stimuli associés à l’administration d’alcool peuvent induire des effets similaires à ceux de l’éthanol. D’autre part, ces stimuli conditionnés à l’éthanol peuvent aussi engendrer des réponses conditionnées opposées aux effets de l’éthanol. Ces deux types de réponses conditionnées semblent jouer un rôle dans les différentes étapes de l’alcoolisation. Leur implication dans la tolérance envers l’éthanol est largement illustrée par le phénomène de tolérance dépendante de l’environnement. Plusieurs études expérimentales et observations cliniques suggèrent aussi que les processus de conditionnement pourraient être impliqués dans la consommation d’alcool et particulièrement dans son abus. Toutefois, les bases neurochimiques de ces réponses conditionnées à l’éthanol sont encore largement méconnues. De récentes études utilisant la technique de microdialyse intracérébrale ont pourtant montré le rôle de divers neurotransmetteurs et neuromodulateurs. D’une part, les réponses conditionnées similaires à l’éthanol sont accompagnées d’une libération de dopamine dans le noyau accumbens. D’autre part, la libération conditionnée de glutamate et de taurine semble être impliquée dans les réponses conditionnées opposées aux effets de l’éthanol. [less ▲]

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See detailSymptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. A double blind, prospective, placebo-controlled study.
Appelboom, T; Schuermans, J; Verbruggen, G et al

in Scandinavian Journal of Rheumatology (2001), 30(4), 242-7

OBJECTIVES: We compare the symptomatic effects of 300 or 600mg daily of ASU in patients with knee osteoarthritis. METHODS: A multicenter, double blind, study comparing a daily intake of 300mg or 600mg of ... [more ▼]

OBJECTIVES: We compare the symptomatic effects of 300 or 600mg daily of ASU in patients with knee osteoarthritis. METHODS: A multicenter, double blind, study comparing a daily intake of 300mg or 600mg of ASU and placebo. The study lasted 3 months and involved patients of both genders, aged 45 to 80 years and presenting with femoro-tibial knee osteoarthritis. The primary endpoint was NSAIDs and analgesics intake between D30 and D90. RESULTS: All efficacy parameters were significantly improved (p<0.01), in the two ASU groups compared to the placebo group. At D90, NSAIDs and analgesics intake decreased by more than 50% in 71% of the patients receiving ASU 300mg or 600mg, compared to 36% of the patients receiving placebo. From DO to D90 Lequesne's index dropped by 3.9 and 2.9 points in ASU 300mg and 600mg groups, respectively, against 1.6 in those receiving placebo. CONCLUSION: The efficacy of ASU at a dosage of 300mg/day and 600mg/day was consistently superior to that of placebo at all endpoints, with no differences observed between the two doses. [less ▲]

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See detailRapport sur le “Workshop on the open archive initiative (OAI) and peer review journals in Europe” - Genève (CERN) 22 au 24 mars 2001
Jérôme, Simone

in Cahiers de la Documentation = Bladen voor Documentatie (2001), (4), 59-63

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See detailHIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases.
Michiels, C.; Minet, E.; Michel, G. et al

in IUBMB Life (2001), 52(1-2), 49-53

HIF-1 is the main transcription factor responsible for increased gene expression in hypoxia: VEGF, erythropoietin, GLUT-1, and glycolytic enzymes are such target genes and all participate in the ... [more ▼]

HIF-1 is the main transcription factor responsible for increased gene expression in hypoxia: VEGF, erythropoietin, GLUT-1, and glycolytic enzymes are such target genes and all participate in the adaptative response of cells to hypoxia. AP-1 activation by hypoxia has also been demonstrated in several cell lines and it cooperates with HIF-1 for increasing VEGF gene transcription in hypoxia. Both HIF-1 and AP-1 activation by hypoxia seems to involve members of the MAP kinase family. Here, we summarize the data indicating that ERK and JNK are needed for activation of HIF-1 and AP-1, respectively. [less ▲]

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See detailCommentaire
Richelle, Marc ULg

in Intellectica (2001), 33

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See detailPerspectives de vaccination anti-dermatophytique chez les carnivores domestiques
Descamps, F.; Brouta, F.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (2001), 145

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See detailL'indexation de l'allocation pour l'aide d'une tierce personne : deux lectures distinctes pour un même problème.
Michiels, Olivier ULg

in Revue Générale des Assurances et des Responsabilités (2001)

L'article s'attache à cerner la jurisprudence divergente de la Cour de cassation et de la Cour d'arbitrage - devenue constitutionnelle - relative à l'indexation de l'allocation pour l'aide d'une tierce ... [more ▼]

L'article s'attache à cerner la jurisprudence divergente de la Cour de cassation et de la Cour d'arbitrage - devenue constitutionnelle - relative à l'indexation de l'allocation pour l'aide d'une tierce personne. [less ▲]

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See detailComparison of deposition images obtained by use of an ultrafine 99m-technetium-labeled carbon dry aerosol with ventilation images obtained by use of 81m-krypton gas for evaluation of pulmonary dysfunction in calves.
Votion, Dominique ULg; Coghe, J. D.; Lekeux, Pierre ULg

in American Journal of Veterinary Research (2001), 62(12), 1881-6

OBJECTIVE: To characterize the accuracy of an ultrafine 99m-technetium-labeled carbon dry aerosol for use in assessment of regional ventilation in calves with pulmonary dysfunction. ANIMALS: 7 Belgian ... [more ▼]

OBJECTIVE: To characterize the accuracy of an ultrafine 99m-technetium-labeled carbon dry aerosol for use in assessment of regional ventilation in calves with pulmonary dysfunction. ANIMALS: 7 Belgian White and Blue calves. PROCEDURE: The ultrafine aerosol was assessed by comparing deposition (D) images with ventilation (V) images obtained by use of 81 m-krypton (81mKr) gas via D-to-V ratio (D:V) image analysis in calves during spontaneous breathing (SB) and during experimentally induced pulmonary dysfunction (ePD). RESULTS: Mismatching index (LrTot) calculated on the D:V images revealed a good match (LrTot, 0.96 +/- 0.01) between D and V distribution patterns in calves during SB. Calculation of the ultrafine aerosol penetration index relative to 81mKr (PIRel) revealed preferential distribution of the ultrafine aerosol in lung parenchyma (PIRel, 1.13 +/- 0.11). In ePD, heterogeneity in the D:V distribution was observed (LrTot, 0.78 +/- 0.10) as a result of ultrafine aerosol particles impaction in airways as indicated by PIRel (0.66 +/- 0.16) and a proportion of pixels more radioactive in D images, compared with V images, that was located in the central part of the lung (475 +/- 77% in ePD vs 32.8 +/- 5.7% in SB). However, this central deposition did not prevent visual examination of the entire ventilated lung. CONCLUSIONS AND CLINICAL RELEVANCE: The ultrafine aerosol appears suitable for use in examination of ventilated parts of lungs of cattle, even those with impaired pulmonary function. However, airway impaction of ultrafine aerosol particles impedes the quantification of regional ventilation in cattle with abnormal lung function. [less ▲]

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See detailA Plea to Bridge the Gap between Antifungals and the Management of Onychomycosis
ARRESE ESTRADA, Jorge ULg; Pierard-Franchimont, Claudine ULg; Pierard, Gérald ULg

in American Journal of Clinical Dermatology (2001), 2(5), 281-4

Onychomycosis represents a stubborn problem for the clinician facing up to the realities of antifungal treatments. There are obvious discrepancies between data given by in vitro antifungal testings ... [more ▼]

Onychomycosis represents a stubborn problem for the clinician facing up to the realities of antifungal treatments. There are obvious discrepancies between data given by in vitro antifungal testings, pharmacodynamics and pharmacokinetics, and those gathered from clinical experience. This critical review is an attempt at bridging the gap between in vitro and in vivo information about oral antifungals that aim to treat onychomycoses. Common sense shows that the in vitro concept of fungicidy cannot be simply extrapolated into clinical practice. Indeed, chlamidoconidia and arthroconidia present in vivo are much more resistant to antifungals than hyphae. Corneofungimetry may be a realistic bioassay in predicting antifungal activity in human infections. Boosting hyphae growth from conidia while taking antifungals is a new and appealing treatment modality that deserves controlled study. [less ▲]

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See detailÉtude de l'influence de l'hydrodynamique sur une bactérie filamenteuse par analyse d'images
Groslambert, Sylvie ULg; Blacher, Silvia ULg; Crine, Michel ULg

in Récents Progrès en Génie des Procédés (2001), 78(18), 153-158

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See detailComment j'explore ... une myopathie par biopsie musculaire
Deprez, Manuel ULg

in Revue Médicale de Liège (2001), 56(1), 49-52

Muscle biopsy is a valuable tool in the diagnosis of many neuromuscular disorders. It is an invasive investigation that will be considered after careful clinical examination, supplemented by biological ... [more ▼]

Muscle biopsy is a valuable tool in the diagnosis of many neuromuscular disorders. It is an invasive investigation that will be considered after careful clinical examination, supplemented by biological and electrophysiological studies. The biopsy procedure and the subsequent processing of specimen in the laboratory significantly influence the information provided by the microscopic examination of muscle tissue. They are reviewed in details in this article. Close collaboration between clinicians and neuropathologists in the setting of an optimized procedure will further increase the diagnostic yield of muscle biopsy. [less ▲]

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See detailInhibition of protein phosphatase PP1 in GH3B6, but not in GH3 cells, activates the MEK/ERK/c-fos pathway and the human prolactin promoter, involving the coactivator CPB/p300
Manfroid, Isabelle ULg; Martial, Joseph ULg; Muller, Marc ULg

in Molecular Endocrinology (Baltimore, Md.) (2001), 15(4), 625-37

The human (hPRL) PRL gene proximal promoter (-164/+15) is the target for numerous signal transduction pathways involving protein kinases. The inhibitor of Ser/Thr-protein phosphatases okadaic acid (OA ... [more ▼]

The human (hPRL) PRL gene proximal promoter (-164/+15) is the target for numerous signal transduction pathways involving protein kinases. The inhibitor of Ser/Thr-protein phosphatases okadaic acid (OA) was shown to induce this promoter in rat pituitary GH3B6 through a synergism between increased amounts of the ubiquitous factor AP-1 and the pituitary-specific factor Pit-1. Here we show that this activation results mainly from transcriptional stimulation of the c-fos promoter leading to increased AP-1 activity. We report the surprising absence of the hPRL and c-fos promoter stimulation by OA in GH3 cells, closely related to GH3B6 cells, and we use this discrepancy to dissect the precise mechanism of action. c-fos gene activation involves the mitogen-activated kinase (MAPK)-ternary complex factor (TCF) pathway and can be obtained by expressing active V12ras in both cell lines. We show that OA acts by inhibiting protein phosphatase PP1, thereby protecting MAPK kinase (MEK)1/2 and/or a MEK1/2-kinase from dephosphorylation. PP1 inhibition of MEK activation by V12ras does not occur in GH3 cells, indicating that a distinct, PP1-sensitive phosphorylation site is used in GH3B6 cells to activate the TCF pathway in GH3B6 cells. Finally, we show that the synergistic OA activation of the hPRL promoter by Pit-1 and AP-1 is independent of the Pit-1 transactivation domain and is mediated by the general coactivator (CRE-binding protein)-binding protein (CBP)/p300. [less ▲]

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See detailCrystal Structure of Human Peroxiredoxin 5, a Novel Type of Mammalian Peroxiredoxin at 1.5 Ǻ Resolution
Declercq, Jean-Paul; Evrard, Christine ULg; Clippe, André et al

in Journal of Molecular Biology (2001), 311

The peroxiredoxins define an emerging family of peroxidases able to reduce hydrogen peroxide and alkyl hydroperoxides with the use of reducing equivalents derived from thiol-containing donor molecules ... [more ▼]

The peroxiredoxins define an emerging family of peroxidases able to reduce hydrogen peroxide and alkyl hydroperoxides with the use of reducing equivalents derived from thiol-containing donor molecules such as thioredoxin, glutathione, trypanothione and AhpF. Peroxiredoxins have been identified in prokaryotes as well as in eukaryotes. Peroxiredoxin 5 (PRDX5) is a novel type of mammalian thioredoxin peroxidase widely expressed in tissues and located cellularly to mitochondria, peroxisomes and cytosol. Functionally, PRDX5 has been implicated in antioxidant protective mechanisms as well as in signal transduction in cells. We report here the 1.5 Ǻ resolution crystal structure of human PRDX5 in its reduced form. The crystal structure reveals that PRDX5 presents a thioredoxin-like domain. Interestingly, the crystal structure shows also that PRDX5 does not form a dimer like other mammalian members of the peroxiredoxin family. In the reduced form of PRDX5, Cys47 and Cys151 are distant of 13.8 Ǻ although these two cysteine residues are thought to be involved in peroxide reductase activity by forming an intramolecular disul®de intermediate in the oxidized enzyme. These data suggest that the enzyme would necessitate a conformational change to form a disulfide bond between catalytic Cys47 and Cys151 upon oxidation according to proposed peroxide reduction mechanisms. Moreover, the presence of a benzoate ion, a hydroxyl radical scavenger, was noted close to the active-site pocket. The possible role of benzoate in the antioxidant activity of PRDX5 is discussed. [less ▲]

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See detailHpa Axis Dysfunction in Major Depression: Relationship to 5-Ht(1a) Receptor Activity
Pitchot, William ULg; Herrera, C.; Ansseau, Marc ULg

in Neuropsychobiology (2001), 44(2), 74-7

Major depression is associated with a dysfunction of the serotonergic activity and the hypothalamic-pituitary-adrenal (HPA) axis. Moreover, a reciprocal relationship between the serotonergic and HPA axis ... [more ▼]

Major depression is associated with a dysfunction of the serotonergic activity and the hypothalamic-pituitary-adrenal (HPA) axis. Moreover, a reciprocal relationship between the serotonergic and HPA axis systems has been hypothesized. The purpose of the present study was to assess the relationship between sensitivity of 5-HT(1A) receptors as measured by hormonal (ACTH, cortisol and PRL) and temperature responses to flesinoxan and HPA axis activity as measured by the dexamethasone suppression test. The sample included 21 inpatients with major depression. Dexamethasone nonsuppressors exhibited lower ACTH responses to flesinoxan as compared with dexamethasone suppressors. The results showed that a dysfunction in 5-HT(1A) receptor activity could be due to a hypersecretion of cortisol. [less ▲]

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See detailEthno-agricultural approach to the rural environment in the prevention of Kashin-Beck disease
Malaisse, François ULg; Haubruge, Eric ULg; Mathieu, Françoise et al

in International Orthopaedics (2001), 25

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See detailImmunisation against East Coast fever by the infection and treatment method: evaluation of the use of ice baths for field delivery and appraisal of an acid formulation of long-acting tetracycline.
Marcotty, T.; Billiouw, M.; Chaka, G. et al

in Veterinary Parasitology (2001), 99(3), 175-87

Immunisation by the infection and treatment method using the Katete strain is currently the most efficient prophylactic technique to control East Coast fever (ECF) in the endemic areas of the Eastern ... [more ▼]

Immunisation by the infection and treatment method using the Katete strain is currently the most efficient prophylactic technique to control East Coast fever (ECF) in the endemic areas of the Eastern Province of Zambia. The maintenance of the cold chain in liquid nitrogen up to the time of inoculation and the cost of the reference long-acting oxytetracycline (Terramycin LA, Pfizer) are the main drawbacks of the method. The work presented in this paper aims at reducing the cost of immunisation against ECF by using an ice bath for the field delivery and a cheaper long-acting oxytetracycline formulation as chemotherapeutic agent. In experimental conditions, the results from 40 calves immunised after various periods of storage on ice ranging from 4 to 32 h indicate that deferred immunisation performed with a stabilate kept on ice for up to 6h after thawing has an efficiency of 90%. Moreover, sporozoites kept on ice were still surviving 32 h after thawing. In a field trial, 91 calves were inoculated with a stabilate kept for 3.5-5.5 h after thawing and dilution whereas 86 calves were immunised using the standard method. Clinical and parasitological reactions to immunisation were monitored as well as the seroconversion. In the field trial, the deferred immunisation was more efficient than the standard method. The acid formulation of oxytetracycline that was tested was found as suitable as the reference alkaline formulation for the chemotherapeutic control of the Katete strain in ECF immunisation. One indoor trial was carried out on 10 animals and a field trial involved 93 calves. [less ▲]

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See detailDiagnosis of vertical velocities with the QG Omega equation: a relocation method to obtain pseudo-synoptic data sets
Rixen, Michel; Beckers, Jean-Marie ULg; Allen, J. T.

in Deep-Sea Research Part I, Oceanographic Research Papers (2001), 48(6), 1347-1373

The quantification of vertical motion and vertical fluxes is essential in our ability to predict and tolerate climate change. However, diagnostic estimations might be affected by the errors arising from ... [more ▼]

The quantification of vertical motion and vertical fluxes is essential in our ability to predict and tolerate climate change. However, diagnostic estimations might be affected by the errors arising from the necessary compromise between spatio-temporal resolution and cost of hydrographic surveys. Observations of a numerical ocean model have been made in order to test the accuracy of different sampling strategies and their possible a-posteriori corrections. A simple first-order correction method, computing a pseudo-synoptic data set from a non-synoptic data set and involving a geostrophic relocation of the stations is shown to correct significantly the synopticity error in hydrographic data, derived QG vertical motion and vertical temperature fluxes. Sensitivity analyses also show that the lack of synopticity is more critical than other factors, including the sampling resolution, the level of no-motion and the analysis. (C) 2001 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailCaractéristiques de la reproduction dans l’espèce caprine
Zarrouk, A.; Souilem, O.; Drion, Pierre ULg et al

in Annales de Médecine Vétérinaire (2001), 145

This review pointed out the physiological basis of goat reproduction. So far assimilated to ewes, goats presented their own characteristics concerning the sexual activity and the endocrinology of ... [more ▼]

This review pointed out the physiological basis of goat reproduction. So far assimilated to ewes, goats presented their own characteristics concerning the sexual activity and the endocrinology of pregnancy. The well understanding of goat particularities is essential to control cyclic activities and reproduction applicationCe travail passe en revue les bases physiologiques de la reproduction dans l’espèce caprine. Longtemps assimilée à la brebis, la chèvre présente des spécificités propres, tant sur le plan du déroulement des cycles sexuels que sur le plan de l’endocrinologie de la gestation. Une bonne connaissance des particularités de la reproduction dans cette espèce permet une meilleure maîtrise du contrôle du cycle sexuel et des techniques de la reproduction [less ▲]

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See detailCompact holographic camera based on photorefractive crystals and application in interferometry
Georges, Marc ULg; Scauflaire, Véronique; Lemaire, Philippe

in Optical Materials (2001), 18

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See detailJuifs et Romains. Y a-t-il eu un antijudaïsme romain ?
Rochette, Bruno ULg

in Revue des Etudes Juives (2001), 160

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See detailLa dopamine dans les troubles de l'humeur
PITCHOT, William ULg

in Neurone (2001), 6(8), 255-258

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See detailContrebande de cigarettes: un exemple moderne de délinquance d'entreprise
Dantinne, Michaël ULg

in Revue Internationale de Criminologie et de Police Technique et Scientifique [= RICPTS] (2001), (1), 3-25

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See detailInfo-congres. La cochrane collaboration, porte-parole de la medecine factuelle.
Scheen, André ULg

in Revue Médicale de Liège (2001), 56(11), 796-8

During the 9th International Cochrane Colloquium (Lyon October 9-13, 2001), around 700 participants discussed about how to make the evidence dissemination process more efficient in order to promote the ... [more ▼]

During the 9th International Cochrane Colloquium (Lyon October 9-13, 2001), around 700 participants discussed about how to make the evidence dissemination process more efficient in order to promote the Evidence-Based Medicine. The best evidence is summarized in systematic reviews of randomised and/or controlled clinical trials within the Cochrane Library which are prepared with a high methodological quality. However, these reviews should be completed to cover all medical domains, be actualized regularly, and, most importantly, be better known and more largely used by physicians in routine practice. All these objectives could not be attained without an official recognition and a financial support by the public health authorities. [less ▲]

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See detailNicardipine Protocol for Cabg Using the Radial Artery Clinical and Angiographic Data
RADERMECKER, Marc ULg; Grenade, Thierry ULg; Cao-Thian, S. K. et al

in Acta Chirurgica Belgica (2001), 101(4, Jul-Aug), 185-9

The routine use of arterial grafts in coronary surgery is facilitated by peroperative adjunction of antispasmodic drug to reduce the event of spasm. Diltiazem has been favoured in most clinical studies ... [more ▼]

The routine use of arterial grafts in coronary surgery is facilitated by peroperative adjunction of antispasmodic drug to reduce the event of spasm. Diltiazem has been favoured in most clinical studies devoted to the radial artery graft. The aim of this study was to assess the efficacy of a spasm preventing protocol associating hydrostatic dilation of the graft with a diluted solution of papaverine and nicardipine infusion, starting preoperatively and continued postoperatively in i.v. and per os forms. Between September 1996 and March 1997, a consecutive series of 50 patients underwent myocardial revascularization using the radial artery. The radial artery was prepared by hydrostatic dilation with papaverine (1%) and nicardipine was administrated at 0.25 microgram/kg/min and titrated according to the arterial systemic pressure. Operative mortality was 4% (sepsis). There was no evidence of perioperative MI nor hypoperfusion syndrome. Mean CKMB level at 18 hours was 36 micrograms/l. No ischaemic anomalies of the ECG were detected. Angiography performed in the last 20 patients showed a 98% (51/52) permeability rate for all graft; 19/20 radial grafts (95%) were patent. One radial graft presented a 50% stenosis at the proximal anastomosis, and another a moderate spasm (40%) in the middle part of the conduit. This study confirms that the radial artery conduit can be used with satisfactory results for routine coronary artery bypass. The use of nicardipine allows the control the vasoreactivity of the radial graft without totally obviating at least angiographic spasm. This drug is easy to titrate, and well tolerated in association to beta-blockers in the routine perioperative management of the coronary patients. [less ▲]

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See detailLe concept d'insulinosensibilite
Scheen, André ULg

in Diabètes & Métabolism (2001), 27(2 Pt 2), 193-200

Insulin resistance was already suspected in the thirties from clinical observations in diabetic patients, then better appreciated in the early sixties with the development of insulin radioimmunoassay, and ... [more ▼]

Insulin resistance was already suspected in the thirties from clinical observations in diabetic patients, then better appreciated in the early sixties with the development of insulin radioimmunoassay, and finally confirmed in the last 20 years by using various sophisticated methods able to quantify insulin action. First demonstrated in obese and/or type 2 diabetic patients, the diminution of insulin sensitivity may in fact concern a much larger population. The concept of insulin sensitivity gained a considerable importance when Reaven, in 1988, emphasized the role of insulin resistance in different human diseases. The metabolic syndrome or syndrome X is characterized by the association of various cardiovascular risk factors (among which impaired glucose tolerance, arterial hypertension and dyslipidaemias), all closely linked to insulin resistance which is indeed the core of the syndrome. Even if insulin action signalling appears to be rather complex and the mechanisms leading to insulin resistance still largely unknown, it is essential to develop pharmacological or non pharmacological strategies to improve insulin sensitivity for treating insulin-resistant individuals. Such an approach should allow not only to provide a better blood glucose control in patients with type 2 diabetes, but also to improve the cardiovascular prognosis of numerous patients, with or without diabetes mellitus, who have the metabolic syndrome. [less ▲]

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See detailA Parametric Distance Function Approach for Malmquist Productivity Index Estimation
Fuentes, Hugo J.; Grifell-Tatjé, Emili; Perelman, Sergio ULg

in Journal of Productivity Analysis (2001), 15

Malmquist indexes of productivity are generally estimated using index number techniques or non-parametric frontier approaches. The aim of this paper is to showthat Malmquist indexes can be estimated in a ... [more ▼]

Malmquist indexes of productivity are generally estimated using index number techniques or non-parametric frontier approaches. The aim of this paper is to showthat Malmquist indexes can be estimated in a similar way using parametric-deterministic or parametric-stochastic frontier approaches. To allow a multi-output multi-input technology and for technical change in production, we adopt an output distance function which is specified in a translog form. We then show that using the estimated parameters, several radial distance functions can be calculated and combined in order to estimate and decompose the productivity index. Finally, this approach is applied to a panel of Spanish insurance companies. The main results confirm those generally obtained for financial services: very low rates of growth and technical change in spite of a rapid deregulation process and expansion of activity. [less ▲]

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See detailAmputations in Diabetic Patients: A Plea for Footsparing Surgery
Van Damme, Hendrik ULg; Rorive, Marcelle ULg; Martens De Noorthout, B. M. et al

in Acta Chirurgica Belgica (2001), 101(3, May-Jun), 123-9

The authors observed a rather high rate of primary major amputation (above-knee or below-knee) performed for diabetic foot problems as well as an important revision rate for minor amputations (forefoot or ... [more ▼]

The authors observed a rather high rate of primary major amputation (above-knee or below-knee) performed for diabetic foot problems as well as an important revision rate for minor amputations (forefoot or toe) in diabetics. They reviewed their experience in order to compare it with more recent data from the literature, pleading for foot-sparing surgery. From 1993 to 1998, 186 amputations were performed on 146 diabetic patients. The cause of foot ulcers was neuropathy in 43 of them (51 episodes of diabetic foot problems) while in the remaining 103 patients (135 episodes of diabetic foot problems), diabetic macroangiopathy (absent ankle pulses) was on cause. For neuropathic foot problems, amputations were almost minor, resulting in a limb salvage rate of 90%. Only five of these patients (12%) had primary major limb amputation versus 43 of the dysvascular patients (42%). The reasons for major amputation by first intention were extensive tissue loss, intractable infection or non-reconstructible occlusive vessel disease, as judged by the surgeon. A foot-sparing surgery was attempted in 92 dysvascular cases. In only 44 of them, a preliminary vascular repair was performed. Twenty eight percent of the primary toe amputations and 24% of the forefoot amputations required secondary revision to a more proximal level. Minor amputations in case of diabetic neuropathy were characterized by a more favourable outcome: only 14% of the toe and 9% of the forefoot amputations failed. During follow-up, only 63% of the major amputations regained an autonomic walking capability with their prosthesis. Wound healing problems in diabetic foot are mainly due to infection and poor tissue perfusion. An aggressive control of the infection and distal revascularization of calf- or foot arteries, whenever possible, could improve the results of diabetic foot surgery. The poor functional recovery after major amputation (only 63% autonomic gait with limb prosthesis) argues for foot-sparing surgery whenever possible. [less ▲]

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See detailNovel plasma extraction procedure and development of a specific enzyme immunoassay of oxytocin: application to biological and clinical investigations of small-cell carcinoma of the lung
Pequeux, Christel ULg; Hendrick, Jean-Claude; Hagelstein, Marie-Thérèse ULg et al

in Scandinavian Journal of Clinical & Laboratory Investigation (2001), 61(5), 407-415

Paraneoplastic secretion of the lactation-inducing hormone oxytocin (OT) has been reported in about 30% of cases of small cell carcinoma of the lung (SCCL). In order to investigate the role of OT in the ... [more ▼]

Paraneoplastic secretion of the lactation-inducing hormone oxytocin (OT) has been reported in about 30% of cases of small cell carcinoma of the lung (SCCL). In order to investigate the role of OT in the biology of SCCL tumours, a specific enzyme-immunoassay(EIA) for OT, which can be applied to both human plasma <br />and culturemedium, has been developed. OT EIA is performed on 96-well microtiter plates coated with a rabbit polyclonal antibody (Ab) anti-OT (O4). This antibody does not exhibit any significant cross-reactivity either with vasopressin (VP) or with vasotocin (VT). The immunological reaction involving Ab anti-OT is a competition between the tracer (biotinylatedOT) and syntheticOT (standard curve) or OT present in biological samples. In order to limit interference induced by plasma proteins, plasma samples are titrated by a one-step centrifugation on centricon YM-3 (cut-oOE 3000 Da). After plasma filtration, 90.7 ± 5.1 (SD) % (n = 22) immunoreactive ( IR) OT is recovered. The sensitivity of OT EIA is 1 pmol/L, while intra- and inter-assay coefficients of variation (CV) are around 3.41% and 2.84%, respectively. In healthy volunteers, plasma IR OT is 7.28 ± 4.49 (SD) pmol/L (n = 32) with no gender diOEerence. As shown by the data both from plasma of SCCL patients and from supernatants and cell contents of SCCL cell lines, this EIA procedure offers a novel, reproducible, specific and sensitive method for the measurement of IR OT. [less ▲]

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See detailConstruire des indicateurs internationaux d'équité des systèmes éducatifs
Demeuse, Marc ULg; Baye, Ariane ULg; Straeten, Marie-Hélène et al

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 97-100

Les membres du SPE se préoccupent de longue date des problèmes d'équité éducative (Crahay, 2000). Ils contribuent soit à l'évaluation de celle-ci dans le système belge francophone ou au sein d'autres ... [more ▼]

Les membres du SPE se préoccupent de longue date des problèmes d'équité éducative (Crahay, 2000). Ils contribuent soit à l'évaluation de celle-ci dans le système belge francophone ou au sein d'autres systèmes à travers des recherches internationales, telles celles de l'IEA ou de l'OCDE (Demeuse, Crahay [less ▲]

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See detailThe Composite Genome Of The Legume Symbiont Sinorhizobium Meliloti
Galibert, Francis; Finan, Turlough M.; Long, Sharon R. et al

in Science (2001), 293(5530),

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See detailA propos du grec diglôssos
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2001), 70

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See detailBreakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment containing the DLK1 and GTL2 genes.
Berghmans, S.; SEGERS, Karin ULg; Shay, T. et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (2001), 12(2), 183-5

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See detailInvestigation of defect levels in Mg-doped GaN Schottky structures by thermal admittance spectroscopy
Nguyen, Ngoc Duy ULg; Germain, Marianne; Schmeits, Marcel et al

in Physica Status Solidi B. Basic Research (2001), 228

Schottky structures based on Mg-doped GaN layers grown by metalorganic chemical vapor deposition (MOCVD) on sapphire substrate are studied by thermal admittance spectroscopy from 90 K to room temperature ... [more ▼]

Schottky structures based on Mg-doped GaN layers grown by metalorganic chemical vapor deposition (MOCVD) on sapphire substrate are studied by thermal admittance spectroscopy from 90 K to room temperature. Evidence of two impurity levels results from the analysis of the observed peaks in the conductance curves, whose positions and strengths are temperature dependent. The experimental results are analyzed within a detailed theoretical study of the steady-state and small-signal electrical characteristics of the structure. Numerical simulations are based on the solution of the basic semiconductor equations for the structure consisting of two Schottky diodes connected back-to-back by a conduction channel formed by the GaN layer. [less ▲]

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See detailThe Secret History of Belgian Surrealism
Delville, Michel ULg

in Samizdat (2001)

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See detailFlow interruption effects on intake rate and rill erosion in two soils
Sirjacobs, Damien ULg; Shainberg, Itzhak; Rapp, Ido et al

in Soil Science Society of America Journal (2001), 65

Efficiency of surface irrigation is often low because of poor infiltration uniformity, resulting from relatively long periods of infiltration at the upstream end and short periods of infiltration at the ... [more ▼]

Efficiency of surface irrigation is often low because of poor infiltration uniformity, resulting from relatively long periods of infiltration at the upstream end and short periods of infiltration at the downstream end of the field. Surge irrigation, the intermittent supply of water to furrows, generally reduces soil intake rate (IR) and improves moisture uniformity over the entire field. However, IR reduction varies from one irrigation scheme to another, depends on soil and water properties, and is difficult to predict. A laboratory study using miniflumes was designed to investigate the effect of interrupted flow on IR and soil loss from short rills. Two soils differing in their textures, a silt loam (Calcic Haploxeralf) derived from loess and a clay soil (Typic Haploxerert), were studied. Intake rate in the clay soil was greater than that in the silt loam. Therefore, different inflow rates were applied to the two soils to achieve similar runoff flow rates from the two soils. Cumulative infiltration decreased from 646 mL in continuous flow to 539 mL in interrupted flow for the silt loam and from 1142 to 1068 mL in the clay soil. Interrupted flow also reduced cumulative soil loss by 84% in the clay soil but had only a small effect on soil loss from the silt loam. However, when flow rate was increased from 80 to 320 mL min−1, interrupted flow reduced soil loss in the silt loam as much as in the clay soil. Consolidation of the soil surface and formation of cohesive forces between soil particles of the silt loam with unstable structure during flow interruption was suggested as the explanation for the effect of flow interruption on intake rate and soil detachment. These results need to be verified in field experiments. [less ▲]

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See detailAnatomical characteristics of tension wood and opposite wood in young inclined stems of poplar (Populus euramericana cv ‘Ghoy’)
Jourez, Benoît ULg; Riboux, Alain; Leclercq, André

in IAWA Journal (2001), 22(2), 133-157

Young shoots from poplar cuttings (P. euramericana cv ‘Ghoy’) were artificially inclined to 30° from vertical to quantify the anatomical modifications induced by this gravitational stimulus. At the end of ... [more ▼]

Young shoots from poplar cuttings (P. euramericana cv ‘Ghoy’) were artificially inclined to 30° from vertical to quantify the anatomical modifications induced by this gravitational stimulus. At the end of the growing season, the tension wood tissue (from the upper face of the inclined axis) was compared to the opposite wood tissue (from the lower face), with radial position taken into account. On isolated elements after maceration, fibres and vessels were significantly longer in tension wood tissue. In the cross section, the gelatinous fibres had a smaller radial diameter than normal fibres in opposite wood. Vessel frequency and porosity were significantly lower in tension wood than opposite wood. Solitary vessels in tension wood were less circular in cross section than in opposite wood, but their surface area did not differ. Rays were more numerous in tension wood than opposite wood but their height did not differ between the two tissue types. Finally, there was a negative correlation between the proportion of vessels lumina (lowest in tension wood) and the proportion of fibres lumina including the G layer. The very controlled nature of this experiment (greenhouse, young clonal material, detailed anatomical observations within one growth ring) and the image analysis technology (allowing a large number of observations) enabled us to draw conclusions that may not have been seen in less-controlled experiments and/or those with smaller sample sizes. [less ▲]

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See detailEstimation of shortening rate since late Pleistocene in the Aksu area on the southern flank of the Tianshan
Wang, X.; Jia, C. Z.; Hubert, Aurelia ULg et al

in Science in China. Series D : Earth Sciences (2001), 44

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See detailDissipative forces and external resonances
Jancart, Sylvie ULg; Lemaitre, Anne

in Celestial mechanics and Dynamical Astronomy (2001), 81

We analyze the process of resonance trapping due to Poynting-Robertson drag and Stokes drag in the frame of the restricted 3-body problem and in the case of external mean motion resonances. The numerical ... [more ▼]

We analyze the process of resonance trapping due to Poynting-Robertson drag and Stokes drag in the frame of the restricted 3-body problem and in the case of external mean motion resonances. The numerical simulations presented are computed by using the 3-dimensional extended Schubart averaging (ESA) integrator developed by Moons (1994) for all mean motion resonances. We complete it by adding the contributions of the dissipative forces. To follow the philosophy of the initial integrator, we average the drag terms, but we do not make any expansion in series of eccentricity or inclination. We show our results, especially capture around asymmetric equilibria, and compare them to those found by Beaué and Ferraz-Mello (1993, 1994) and Liou et al. (1979). [less ▲]

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See detailInfluence of culture conditions on lipopeptide production by Bacillus subtilis
Akpa, E.; Jacques, Philippe ULg; Wathelet, Bernard ULg et al

in Applied Biochemistry and Biotechnology (2001), 91-3

Bacillus subtilis produces various families of lipopeptides with different homologous compounds. To produce "new molecules" with improved activities and to select strains that produced a reduced number of ... [more ▼]

Bacillus subtilis produces various families of lipopeptides with different homologous compounds. To produce "new molecules" with improved activities and to select strains that produced a reduced number of homologs or isomers, we studied the effects of different media on the nature of the synthesis of fatty; acid chains for each lipopeptide family. This study focused on two B. subtilis strains cultivated in flasks. Optimized medium for lipopeptide production and Landy medium modified by replacing glutamic acid with other alpha -amino acids were used. We found that the intensity of production of homologous compounds depends on the strain and the culture medium. Analysis of these lipopeptides by high-performance liquid chromatography showed that the strain R. subtilis NT02 yielded various homologous compounds when cultivated in Landy medium (L-Glu), but primarily one homologous product in hi,oh relative amounts when cultivated in the optimized medium. Mass spectrometric analysis and determination of the amino acid composition of this molecule enabled us to identify it as Bacillomycine L c15. [less ▲]

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See detailCrystallographic analysis of family 11 endo-beta-1,4-xylanase Xyl1 from Streptomyces sp. S38.
Wouters, J.; Georis, J.; Engher, D. et al

in Acta Crystallographica Section D-Biological Crystallography (2001), 57(Pt 12), 1813-9

Family 11 endo-beta-1,4-xylanases degrade xylan, the main constituent of plant hemicelluloses, and have many potential uses in biotechnology. The structure of Xyl1, a family 11 endo-xylanase from ... [more ▼]

Family 11 endo-beta-1,4-xylanases degrade xylan, the main constituent of plant hemicelluloses, and have many potential uses in biotechnology. The structure of Xyl1, a family 11 endo-xylanase from Streptomyces sp. S38, has been solved. The protein crystallized from ammonium sulfate in the trigonal space group P321, with unit-cell parameters a = b = 71.49, c = 130.30 A, gamma = 120.0 degrees. The structure was solved at 2.0 A by X-ray crystallography using the molecular-replacement method and refined to a final R factor of 18.5% (R(free) = 26.9%). Xyl1 has the overall fold characteristic of family 11 xylanases, with two highly twisted beta-sheets defining a long cleft containing the two catalytic residues Glu87 and Glu177. [less ▲]

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See detailUne action intégrée en vue d'améliorer l'efficacité des systèmes d'enseignement : Le pilotage des systèmes d'enseignement
Demeuse, Marc ULg; Baye, Ariane ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (5-6), 23-50

Cet article s'inspire largement d'un chapitre du rapport non publié déposé en 1998 auprès de la Communauté européenne dans le cadre d'un projet entrepris grâce aux moyens accordés par l'action III.3.1 du ... [more ▼]

Cet article s'inspire largement d'un chapitre du rapport non publié déposé en 1998 auprès de la Communauté européenne dans le cadre d'un projet entrepris grâce aux moyens accordés par l'action III.3.1 du programme Socrates (Marc Demeuse) [less ▲]

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See detailDiagnosis of psoroptic sheep scab with an improved enzyme-linked immunosorbent assay.
Ochs, H.; Lonneux, J.; Losson, Bertrand ULg et al

in Veterinary Parasitology (2001), 96(3), 233-42

An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of specific antibodies against crude Psoroptes antigen. The diagnostic sensitivity was 93.7% in 191 sheep with clinical signs ... [more ▼]

An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of specific antibodies against crude Psoroptes antigen. The diagnostic sensitivity was 93.7% in 191 sheep with clinical signs associated with mange. These animals originated from 29 flocks in which psoroptic mites were detected. All of 59 sheep infested with Psoroptes ovis were seropositive. Additionally, in 49% of 70 clinically unaffected sheep originating from P. ovis-infested flocks, specific antibodies could be detected, suggesting that asymptomatic infestations can be diagnosed by serology. The specificity of the ELISA was 96.5% as determined with 254 sheep originating from 44 flocks without clinical mange. Cross-reactivity in a low range was detected with selected sera of sheep with clinical chorioptic or forage mite infestations. Four sheep seroconverted 2 weeks after experimental P. ovis infestation, i.e. 2 weeks before clinical signs became obvious. After successful doramectin treatment of 14 sheep with naturally acquired P. ovis infestation, the ELISA values declined slowly but remained positive in seven cases beyond 17 weeks. [less ▲]

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See detailLocalized iterative generalized multipole technique for large two-dimensional scattering problems
Obelleiro, Fernando; Landesa, Luis; Rodriguez, Jose Luis et al

in Ieee Transactions On Antennas And Propagation (2001), 49(6), 961-970

In this work, we propose a novel and efficient solution for the generalized multipole technique (GMT): the localized iterative generalized multipole technique (LIGMT). In LIGMT, an analytic constraint is ... [more ▼]

In this work, we propose a novel and efficient solution for the generalized multipole technique (GMT): the localized iterative generalized multipole technique (LIGMT). In LIGMT, an analytic constraint is imposed on the power radiated by the set of multipole sources sharing the same origin, rendering it minimum over a given angular sector. In this way, the power radiated by each set of multipoles is confined to a different section of the scatterer surface. It follows that each set of multipole coefficients can be solved step by step via an iterative process, which circumvents the need to solve the large and full matrix equation. This implies a significant reduction of the computational and storage cost, enhancing the scope of application of the GMT method to larger problems. [less ▲]

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See detailAugmented Lagrangian procedure for implicit computation of contact-impact between deformable bodies.
Graillet, D.; Ponthot, Jean-Philippe ULg; Stainier, Laurent ULg

in International Journal of Crashworthiness (2001), 6(2), 209-221

This paper shows how efficiency can be improved by using an adequate Augmented Lagrangian procedure instead of the classical and well-known Penalty method for solving contact-impact problems between ... [more ▼]

This paper shows how efficiency can be improved by using an adequate Augmented Lagrangian procedure instead of the classical and well-known Penalty method for solving contact-impact problems between deformable bodies, including frictional contact, large deformations, dynamical effects and inelasticity phenomena The Augmented Lagrangian method has already enjoyed great success in solving constrained minimisation problems or incompressibility conditions. Alternatives to existing automation techniques for augmentations are presented. Starting from a Penalty method, it will be seen how the Augmented Lagrangian decreases ill-conditioning of governing equations and gives a more precise solution with a lower CPU-cost. Several original simultaneous criteria are proposed for optimising the number and the location of the augmentations in an incremental implicit resolution. Application of the method is done for two axisymmetric impact problems. [less ▲]

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See detailEffets benefiques de l'activite physique sur les facteurs de risque cardio-vasculaire.
Scheen, André ULg; Paquot, Nicolas ULg

in Revue Médicale de Liège (2001), 56(4), 239-43

Numerous observational (epidemiological surveys) or interventional (controlled trials) studies demonstrated that regular physical activity increases insulin sensitivity in normal subjects and decreases ... [more ▼]

Numerous observational (epidemiological surveys) or interventional (controlled trials) studies demonstrated that regular physical activity increases insulin sensitivity in normal subjects and decreases insulin resistance in patients with obesity and/or type 2 diabetes. These favourable effects are at least partially linked to a reduction in abdominal fat mass. This results in a significant improvement of lipid profile, with a decrease in the concentrations of total cholesterol, LDL cholesterol and triglycerides, associated with an increase of HDL cholesterol level. Such favourable metabolic effects related to regular physical activity probably explain the better cardiovascular prognosis observed in regularly exercising subjects as compared to sedentary individuals. These observations should motivate any practitioner to promote endurance physical exercise in every subject, especially in individuals at high cardiovascular risk. [less ▲]

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See detailOptimal heating control in a passive solar commercial building.
Kummert, Michaël; Andre, Philippe ULg; Nicolas, Jacques ULg

in Solar Energy (2001), 69(6), 103-116

A smart heating controller has a twofold objective: to save as much energy as possible while maintaining an acceptable comfort level in the building. Due to very large time constants in the building ... [more ▼]

A smart heating controller has a twofold objective: to save as much energy as possible while maintaining an acceptable comfort level in the building. Due to very large time constants in the building response, it has to anticipate internal and external disturbances. In the case of a passive solar commercial building, the need for anticipation is reinforced by important solar and internal gains. Indeed, large solar gains increase the energy savings potential but also the overheating risk. Optimal control theory presents an ideal formalism to solve this problem: its principle is to anticipate the building behaviour using a model and a forecasting of the disturbances in order to compute the control sequence that minimises a given cost function over the optimisation horizon. This cost function can combine comfort level and energy consumption. This paper presents the application of optimal control to auxiliary heating of a passive solar commercial building. Simulation-based and experimental results show that it can lead to significant energy savings while maintaining or improving the comfort level in this type of building [less ▲]

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See detailInsémination artificielle des vaches ‘Azawak’ et taurin ‘Gourunsi’ au Burkina Faso
Zongo, M.; Boly, H.; Sawadogo, L. et al

in Tropicultura (2001), 19(2), 75-78

La synchronisation des chaleurs et la fertilité en insémination artificielle des zébus ‘Azawak’ (Bos indicus, n = 66) et des taurins ‘Gourunsi’ (Bos taurus, n = 20) ont été appréciées en zone périurbaine ... [more ▼]

La synchronisation des chaleurs et la fertilité en insémination artificielle des zébus ‘Azawak’ (Bos indicus, n = 66) et des taurins ‘Gourunsi’ (Bos taurus, n = 20) ont été appréciées en zone périurbaine soudano-sahélienne de Ouagadougou au Burkina Faso. La synchronisation a été effectuée avec des implants sous cutanés de progestagène placés sous la peau de l’oreille pendant 10 jours. Le traitement a été complété par l’injection de prostaglandine F2 et de PMSG, respectivement au 8ième et au 10ième jours de la pose de l’implant. Le taux d’œstrus induits observés par l’éleveur était de 94,2% dans les 48 heures qui suivaient le retrait de l'implant. Il variait significativement (P<0,05) selon les groupes zébus ‘Azawak’ et taurins ‘Gourunsi’ (100% et 75%, respectivement). Les taux de fertilité, déterminés par palpation rectale chez les zébus ‘Azawak’ et les taurins ‘Gourunsi’, ont été respectivement 24,2% et 10%. La fertilité a varié selon le moment de l’insémination: lorsque les femelles étaient inséminées 36 à 48 heures après le retrait de l’implant, les taux de fertilité ont été faibles (0 à 12,5% chez les taurins ‘Gourunsi’ et les zébus ‘Azawak’, respectivement). Par ailleurs, lorsque les inséminations étaient réalisées 24 à 36 heures après le retrait de l’implant, les taux de fertilité ont été respectivement de 50% et 42,3%. [less ▲]

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See detailAbsolute configuration of N-[(R)-3-methyl-2-butyl]-(S)-2-(6-methoxy-2-naphthyl)-propionamide
Dupont, L.; Khellili, S.; Pirotte, Bernard ULg et al

in Acta Crystallographica (2001), E57

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See detailEquilibrium charge-state distributions of sodium ions in carbon foil
Tordoir, Xavier ULg; Bastin, Thierry ULg; Dumont, Paul-Dominique ULg et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2001), 173

The equilibrium charge-state distributions have been measured for sodium ions at the exit of a carbon foil for energies ranging from 0.43 to 1.66 Me V. A comparison of our results with available models is ... [more ▼]

The equilibrium charge-state distributions have been measured for sodium ions at the exit of a carbon foil for energies ranging from 0.43 to 1.66 Me V. A comparison of our results with available models is performed and an empirical formula for calculating the charge-state fractions of sodium ions is deduced. [less ▲]

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See detailPropositions relatives à l'enseignement
de Landsheere, Gilbert ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (5-6), 79-84

Comme pour le texte 'L'avenir de l'enseignement' qui est publié dans ces Cahiers, il s'agit d'un texte qui date d'une dizaine d'années. Ces propositions ont été formulées peu de temps après la ... [more ▼]

Comme pour le texte 'L'avenir de l'enseignement' qui est publié dans ces Cahiers, il s'agit d'un texte qui date d'une dizaine d'années. Ces propositions ont été formulées peu de temps après la communautarisation complète de l'enseignement. A présent que 'nous sommes maîtres chez nous', qu'en est-il ? Quel chemin avons-nous parcouru ? S'agissait-il de prémonitions ? De rêves et d'utopies ? Chacun peut s'en faire une idée. Chacun peut aussi apprécier, sur la base d'un texte, ce qui se disait alors et ce que Gilbert de Landsheere envisageait comme souhaitable. [less ▲]

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See detailEquine Third Metacarpal Bone Assessment by Quantitative Ultrasound and Dual-Energy-X-Ray absorptiometry.
Carstanjen, Bianca; Duboeuf, F.; Amory, Hélène ULg et al

in Veterinary Surgery : The Official Journal of the American College of Veterinary Surgeons (2001), 30

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See detailAerossolterapia nas doenças respiratórias em eqüinos
Bastos da Silva, Miriam; Duvivier, Dominique Hannia; Votion, Dominique ULg et al

in Brazilian Journal of Veterinary Research and Animal Science (2001), 38(2), 88-96

Respiratory problems are frequently implicated in horses as a cause of poor sportive performances. The most frequently occurring lower respiratory tract disorders are chronic obstructive pulmonary disease ... [more ▼]

Respiratory problems are frequently implicated in horses as a cause of poor sportive performances. The most frequently occurring lower respiratory tract disorders are chronic obstructive pulmonary disease (COPD), inflammatory airway disease and exercise-induced pulmonary haemorrhage (EIPH). Classically, their treatment includes systemic administration of drugs, but aerosol therapy is now known to be a more specific way to treat these disorders. This article describes the equipment and drugs currently available for aerosol therapy in horses. [less ▲]

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See detailTime-dependent wave-packet treatment of the Si4+ + He collision
Vaeck, Nathalie; Bacchus-Montabonel, Marie-Christine; Baloïtcha, Ezinvy et al

in Physical Review. A (2001), 63

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See detailLe cas clinique du mois. L'histoire naturelle d'une obesite morbide: aller vers le diabete de type 2 insulinorequerant et retour apres chirurgie bariatrique.
De Flines, Jenny ULg; Letiexhe, Michel ULg; Desaive, Claude ULg et al

in Revue Médicale de Liège (2001), 56(12), 816-22

Morbid obesity is a crucial risk factor in the development of type 2 diabetes and is often associated with a metabolic syndrome closely linked to insulin resistance. This case report illustrates the ... [more ▼]

Morbid obesity is a crucial risk factor in the development of type 2 diabetes and is often associated with a metabolic syndrome closely linked to insulin resistance. This case report illustrates the natural history of morbid obesity, starting during the adolescence and ending with an extremely severe type 2 diabetes at the age of 40. Numerous attempts of weight loss with various medical approaches failed and diabetes mellitus rapidly became insulin-requiring in a context of extreme insulin resistance. Finally, the patient was submitted to a gastric bypass which resulted in a drastic weight loss over 50 kg during the year following surgery without any significant side-effects or complications. Type 2 diabetes almost disappeared and the classical markers of insulin resistance were markedly improved. This clinical case clearly demonstrates that successful management of obesity with bariatric surgery can reverse severe type 2 diabetes. [less ▲]

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See detailPotential of the Migraine Disability Assessment (MIDAS) Questionnaire as a public health initiative and in clinical practice.
Edmeads, J.; Lainez, J. M.; Brandes, J. L. et al

in Neurology (2001), 56(6 Suppl 1), 29-34

Migraine is not always well managed in clinical practice, often being under-diagnosed and under-treated. As a result, many sufferers never consult a physician or lapse from care after physician contact ... [more ▼]

Migraine is not always well managed in clinical practice, often being under-diagnosed and under-treated. As a result, many sufferers never consult a physician or lapse from care after physician contact. Although most migraine care is provided by general practitioners, others, including specialists, emergency room physicians, pharmacists, and alternative practitioners, may also be involved. A method of standardizing clinical information about migraine is essential for coordinated, logical, and systematic care. The impact of migraine on the patient is an important clinical parameter but one that is seldom inquired about, perhaps because it exhibits such marked variability among and within individuals. Headache-related disability can be an objective and measurable index of this impact. The Migraine Disability Assessment (MIDAS) Questionnaire is a simple and validated instrument with potential for use in clinical practice, research, and public health. It can improve communication between patients and health-care professionals regarding the impact of migraine which, in turn, allows tailoring of the intensity of treatment to the severity of the illness. Changes in the MIDAS score may serve as an end point in assessing treatment efficacy. In populations, MIDAS scores may indicate the burden of migraine in the community and spark public health initiatives to improve management. [less ▲]

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See detailInfo-congres. Prevention pharmacologique de la progression de la diminution de la tolerance au glucose vers le diabete de type 2: effets favorables de la metformine et de l'acarbose.
Scheen, André ULg

in Revue Médicale de Liège (2001), 56(10), 727-30

We report the positive results of two large prospective studies of pharmacological prevention of type 2 diabetes presented at the EASD Congress in Glasgow, September 12, 2001. In the "Diabetes Prevention ... [more ▼]

We report the positive results of two large prospective studies of pharmacological prevention of type 2 diabetes presented at the EASD Congress in Glasgow, September 12, 2001. In the "Diabetes Prevention Program", metformin (2 x 850 mg/day), a biguanide compound, reduces the progression from impaired glucose tolerance towards type 2 diabetes by 31% (p < 0.001) while in the "STOP-NIDDM trial", acarbose (3 x 100 mg/day), an alpha-glucosidase inhibitor, diminished it by 24% (p < 0.002). These results are, however, less marked than those obtained with lifestyle modifications including better dietary habits and increased physical exercise (-58% versus control group, p < 0.001). [less ▲]

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See detailComparison between the GIRBAS Scale and the Acoustic and Aerodynamic Measures Provided by EVA for the Assessment of Dysphonia following Unilateral Vocal Fold Paralysis.
Morsomme, Dominique ULg; Jamart, Jacques; Wery, Carine et al

in Folia Phoniatrica et Logopaedica (2001), 53(6), 317-25

The aim of this study is to establish relevant objective parameters for evaluating dysphonia following unilateral vocal fold paralysis. To do so, the study compares objective and perceptual voice measures ... [more ▼]

The aim of this study is to establish relevant objective parameters for evaluating dysphonia following unilateral vocal fold paralysis. To do so, the study compares objective and perceptual voice measures. The objective measures were obtained using a voice analysis software (Evaluation Vocale Assistee), whereas the perceptual measures were established with the GIRBAS Scale (grade, instability, roughness, breathiness, asthenia, and strain). All measurements were performed on 40 voice samples: 28 dysphonic subjects with unilateral laryngeal paralysis, and 12 control subjects. The intra- and inter-judge agreements were fairly good, at least for control subjects. The six GIRBAS measures obtained from the pathological voices were higher than those from the control voices (p < 0.001) and the correlation between both groups was good. Grade, breathiness and asthenia correlated with the objective parameters that express the aperiodicity of the phonatory signal (p < 0.01), namely, the coefficient of variability of the fundamental frequency, the coefficient of variability of intensity, and jitter. Our findings suggest that the perceptual reality of laryngeal paralysis-induced dysphonia depends more on grade, breathiness and asthenia than it does on roughness or instability. [less ▲]

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See detailRecent biogeographic and ecological studies on otter (Lutra lutra) and European mink (Mustela lutreola) in France
de Bellefroid, Marie des Neiges; Libois, Roland ULg; Rosoux, René

in Säugetierkundliche informationen (2001), 25

Otter and European mink are two threatened species in France. The mink is even considered to be on the verge of extinction. Studies have been carried out for more than ten years to attempt to understand ... [more ▼]

Otter and European mink are two threatened species in France. The mink is even considered to be on the verge of extinction. Studies have been carried out for more than ten years to attempt to understand the changes in their distribution and the ecological needs of these two semi-aquatic mustelids. The results of the research programmes completed or still under way, are presented. The French Ministry of Environment has set up two specific restoration plans, with the contribution of Conversation societies for wild fauna and scientific institutions. [less ▲]

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See detailEvaluer une réforme pédagogique : La généralisation de l'apprentissage d'une langue seconde à l'école primaire
Blondin, Christiane ULg; Straeten, Marie-Hélène

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 163-173

La recherche Généralisation de l'apprentissage d'une langue moderne à l'école primaire, réalisée avec le soutien du Ministère de la Communauté française vise à évaluer la mise en place de l'innovation que ... [more ▼]

La recherche Généralisation de l'apprentissage d'une langue moderne à l'école primaire, réalisée avec le soutien du Ministère de la Communauté française vise à évaluer la mise en place de l'innovation que constitue l'enseignement obligatoire des langues en cinquième et sixième années primaires, dans les écoles fondamentales organisées ou subventionnées par la Communauté française.Il est donc nécessaire de récolter un maximum d'informations quant aux ressources des équipes éducatives et plus particulièrement des maîtres de langue face à cette réforme, quant aux difficultés rencontrées, aux aides et aux soutiens possibles, tant d'un point de vue méthodologique qu'institutionnel ou administratif. A terme, cette recherche veut proposer des pistes pour assurer la réussite de l'innovation. Le présent article situe cette recherche dans une perspective de pilotage d'innovation. [less ▲]

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