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See detailLack Of Mutation In The Waf1/Cip1 Gene During Bovine Leukemia Virus-Induced Leukemogenesis
Dequiedt, Franck ULg; Willems, Luc ULg; Kerkhofs, P. et al

in Veterinary Immunology and Immunopathology (1997), 59(3-4),

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See detailAspects of the Upper Palaeolithic in Central Europe
Otte, Marcel ULg; Noiret, Pierre ULg; López Bayón, Ignacio

in Préhistoire Européenne (1997), 11

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See detailDesign for an Ipriflavone Multicenter European Fracture Study
Reginster, Jean-Yves ULg; Bufalino, L.; Christiansen, C. et al

in Calcified Tissue International (1997), 61(Suppl 1), 28-32

In order to investigate the efficacy of ipriflavone (i.p.) on the prevention of vertebral fractures and the effect on bone mineral density (BMD) in women with postmenopausal osteoporosis, a large ... [more ▼]

In order to investigate the efficacy of ipriflavone (i.p.) on the prevention of vertebral fractures and the effect on bone mineral density (BMD) in women with postmenopausal osteoporosis, a large multicentric European study was designed and is presently ongoing. Included in the study were 460 Caucasian, nonobese postmenopausal women aged > 45 and < 75 years, menopaused for at least 12 months. Inclusion was on the basis of a lumbar bone mineral density (BMD) lower than 2 SD compared with healthy women aged 50 years, corresponding to values below 0.860 g/cm2 (antero-posterior measurement) by Hologic QDR 1000. Women with prevalent vertebral fractures were excluded as well as those presenting secondary osteoporosis or having been treated with medications that could affect bone metabolism. This study was designed as a 3-year, double-blind, placebo-controlled, parallel group study that randomized the women to the oral administration of either 3 x 200 mg/day of i.p. or placebo. All patients received a daily supplement of 500 mg calcium. The primary purpose of the study was to evaluate the efficacy of i.p. in preventing vertebral nontraumatic fractures. Fracture is defined here as a > or = 20% decrease in any anterior, central, or posterior T4-L4 vertebral height. Blinded vertebral X-ray readings and vertebral morphometry have been centralized in an independent Center, with standardized evaluation of two experts. Power calculations have been based on the hypothesis that 21% of placebo-treated patients would fracture within 3 years and that treatment with i.p. would lead to a 50% reduction in the incidence of fracture. Statistical tests have been designed to have a power of 80%, with a type I error equal to 5%. Secondary endpoints were changes in vertebral, radial, and femoral BMD. Centralized controls on 100% BMD scans would ensure the good quality of BMD readings. This study should verify the hypothesis that i.p. significantly decreases the risk of vertebral fracture in postmenopausal, osteoporotic women. [less ▲]

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See detailRelationships of k-casein - beta-lactoglobulin and alfa-lactalbumin polymorphisms with estimated breeding values for milk traits in Italian Friesian and Italian Simmental bulls.
Vrech, E.; Prandi, A.; Corradini, C. et al

in Zootecnica e Nutrizione Animale (1997), 23(3),

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See detailSm-Nd signature of modern and late Quaternary sediments from the northwest North Atlantic: Implications for deep current changes since the Last Glacial Maximum
Innocent, C.; Fagel, Nathalie ULg; Stevenson, Ross et al

in Earth & Planetary Science Letters (1997), 146(3-4), 607-625

Nd isotopes and Sm-Nd concentrations have been investigated in the clay size fraction of surface and late Quaternary sediments of the northern North Atlantic. Four sources of Nd have been identified in ... [more ▼]

Nd isotopes and Sm-Nd concentrations have been investigated in the clay size fraction of surface and late Quaternary sediments of the northern North Atlantic. Four sources of Nd have been identified in the surface sediments: (1) a radiogenic Nd typical of the Iceland volcanism; (2) a ''Pan-African'' Nd issued from eastern Greenland; (3) a ''Variscan'' Nd derived from the Arctic Ocean; (4) an old unradiogenic Nd related to the North American Shield, In the Iceland and Irminger basins, the major sources of Nd are the Variscan Nd derived from the Arctic Ocean and the Iceland Nd, except in the western Irminger Basin where the Pan-African Nd originating from eastern Greenland is dominant and labels sedimentary supplies linked to the Denmark Strait Overflow Water, Nd derived from Icelandic volcanism is never clearly dominant, even on the Reykjanes Ridge, and the Nd derived from the American Shield becomes dominant only in the Labrador Sea, Sediments lying in the pathway of the Western Boundary Undercurrent have Nd isotopic compositions which are shifted towards more radiogenic values indicating an input of material from the eastern basins, carried by this deep current. Late Quaternary sediments were cored from the southern Greenland Rise (core 90-013-013) and eastern Labrador Rise (Orphan Knell; core 91-045-094). In core 90-013-013, epsilon Nd values during the Last Glacial Maximum are as low as -20, but subsequently rose to -9 in the modern sediments, indicating that the sedimentary material during the Last Glacial Maximum was dominated by unradiogenic Nd from the North American Shield. This may be related to a lesser outflow of the Western Boundary Undercurrent, In core 91-045-094, located along the Labrador Current trajectory, a dominant supply of North American Shield Nd is recorded, perhaps originating at least partially from the Hudson Strait, The Sm-Nd data are compatible with smectite vs. illite studies at the same sites which suggest a continuous but more modest Western Boundary Undercurrent supply during Last Glacial Maximum. [less ▲]

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See detailEffects of Growth and Breed on Direct Static Measurements of Chest Wall Compliance in Cattle
Desmecht, Daniel ULg; Rollin, Frédéric ULg; Linden, Annick ULg et al

in Research in Veterinary Science (1997), 62(1, Jan-Feb), 1-5

Chest wall compliance (CW) was measured in 59 conscious standing calves, aged six to 162 days, which were breathing air spontaneously through a face mask. The airways were occluded at the end of ... [more ▼]

Chest wall compliance (CW) was measured in 59 conscious standing calves, aged six to 162 days, which were breathing air spontaneously through a face mask. The airways were occluded at the end of inspiration in order to elicit the Hering-Breuer reflex, the effectiveness of which was ensured by the presence of a plateau on the tracings of airway opening and oesophageal pressure (Pes). CW was measured directly from the inspired volume of the occluded breath and changes in Pes generated by the recoil of the relaxed chest wall. This airway-occlusion technique yielded reproducible CW values similar to those measured by classical invasive methods. The ratio of CW to bodyweight in the growing calves (sCW) ranged from 2.2 to 11.5 ml cmH2O-1 kg-1 and was correlated negatively with age: (log sCW = 0.91-0.003 x age, r = 0.68), the rate of decline corresponding well to the multispecies allometric growth relationship. [less ▲]

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See detailThe Color Purple - les Blues Pourpres d'Alice Walker
Sacré, Robert ULg

in Les Cahiers du Jazz (1997), 12

Un livre (1982) - un film ( Steven Spielberg, 1985)

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See detailBilinguisme, traduction et histoire des textes dans l'Orient grec (Ier - IVe s. après J.-C.)
Rochette, Bruno ULg

in Revue d'Histoire des Textes (1997), 27

Vise à montrer l'intérêt que présentent les textes traduits pour l'étude de la transmission de l'original. Trois exemples de traductions du latin en grec, réalisées dans la Pars Orientis entre le Ier et ... [more ▼]

Vise à montrer l'intérêt que présentent les textes traduits pour l'étude de la transmission de l'original. Trois exemples de traductions du latin en grec, réalisées dans la Pars Orientis entre le Ier et le IVe s., sont étudiés : les Res gestae diui Augusti, les listes de mots compilées à partir de Virgile et de Cicéron sur papyrus, la uersio Graeca de la quatrième Bucolique de Virgile appartenant à l'Oratio ad Sanctorum coetum de Constantin le Grand. L'apport de ces traductions se situe sur deux plans. D'abord, constituant une tradition en soi, les traductions grecques d'œuvres latines permettent de connaître l'état du texte au moment de sa traduction et peuvent donc jouer un rôle dans l'ecdotique. Ensuite, ces traductions apportent une contribution à l'histoire de la littérature et des mentalités. La traduction d'un texte se situe dans un contexte culturel différent de celui dans lequel a été élaboré l'original. Loin de se contenter de traduire ad uerbum, le traducteur fait passer dans la version traduite des conceptions nouvelles, politiques, sociales ou religieuses. Ainsi, par exemple, le passage d'un régime politique à un autre (République-Empire) ou d'une conception religieuse à une autre (paganisme-christianisme) peut modifier radicalement la perspective du traducteur. [less ▲]

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See detailStudies on the O-J-I-P transient of chlorophyll fluorescence in relation to photosystem II assembly and heterogeneity in plastids of greening barley
Barthelemy, X.; Popovic, R.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (1997), 39(3), 213-218

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of ... [more ▼]

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of etiolated leaves of Hordeum vulgare. The initial photochemical phase (O-J) due to reduction of the primary quinone acceptor Q(A) was found to represent a constant proportion (65-70%) of total variable fluorescence independent of greening time. The partial fluorescence quenching in the Q(A)-reduced state seems, therefore, to represent a basic property of PSII electron transport. The biphasic character of the slower J-I-P transient due to reduction of the plastoquinone pool developed progressively during the first hours of greening. in the same period of lime the proportion and rate constant of rapid PSII alpha sub-population increased, as calculated from the induction curve in the presence of DCMU. Etiochloroplasts or chloroplasts resuspended in low salt medium showed a low I level, which was restored upon readdition of 5 mM MgCl2 and NaCl. Salts also increased the apparent proportion of PSII alpha. These results suggest that the J-I and I-P phases of the induction curve are related to different rates of plastoquinone photoreduction by two distinct PSII populations. The effects of DMQ and of DCBQ on the O-J-I-P transient were also studied in (etio-)chloroplasts, In addition to the already reported quenching of the initial (F-0) and variable fluorescence by DCBQ, a slow fluorescence increase phase was found to appear upon the addition of DCBQ but not of DMQ. The latter observations confirm that DCBQ differs from DMQ by its higher efficiency as PSII electron acceptor. (C) 1997 Elsevier Science S.A. [less ▲]

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See detailDifférences entre les pathotypes et les sérogroupes des Escherichia coli vérotoxinogènes isolées de veaux sains et celles isolées de veaux souffrant de diarrhée
Pohl, P.; Cleenwerk, I.; Imberechts, H. et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailPolyclonal Bovine Sera But Not Virus-Neutralizing Monoclonal Antibodies Block Bovine Leukemia Virus (Blv) Gp51 Binding To Recombinant Blv Receptor Blvrcp1
Orlik, O.; Ban, J.; Hlavaty, J. et al

in Journal of Virology (1997), 71(4),

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See detailDeconvolution with correct sampling.
Magain, Pierre ULg; Courbin, F.; Sohy, Sandrine ULg

in The Messenger (1997), 88

The authors briefly describe the basic ideas behind a new deconvolution technique which overcomes some of the drawbacks of the traditional methods and which gives results of high photometric and ... [more ▼]

The authors briefly describe the basic ideas behind a new deconvolution technique which overcomes some of the drawbacks of the traditional methods and which gives results of high photometric and astrometric accuracy. The authors also show how it can be combined with other techniques (e.g. adaptive optics) to give even better results. [less ▲]

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See detailFormation of long-wavelength chlorophyllide (Chlide695) is required for the assembly of Photosystem II in etiolated barley leaves
Franck, Fabrice ULg; Eullaffroy, P.; Popovic, R.

in Photosynthesis Research (1997), 51(2), 107-118

Chlorophyll(ide) spectroscopic properties and Photosystem II assembly, monitored by 77 K variable fluorescence, were studied in etiolated barley leaves as a function of the extent of protochlorophyllide ... [more ▼]

Chlorophyll(ide) spectroscopic properties and Photosystem II assembly, monitored by 77 K variable fluorescence, were studied in etiolated barley leaves as a function of the extent of protochlorophyllide photoreduction by a single millisecond light flash of different intensities. Variable fluorescence, measured 2 hours after the flash, was only detected when the extent of phototransformation was higher than a threshold value of 0.4. Its development paralleled the formation of a chlorophyll emission component at 685 nm, which itself derived from long-wavelength chlorophyllide with an emission maximum at 695 nm. At low flash intensities, short-wavelength chlorophyllide forms preferentially accumulated and no Photosystem II fluorescence was detected after 2 hours. Chlorophyllide esterification was independent of the extent of phototransformation. These results suggested that the formation of long-wavelength chlorophyllide was essential for further assembly of Photosystem II. This interpretation was strengthened by the observed inhibition of both long-wavelength chlorophyllide formation and of variable fluorescence development in leaves treated with 6-aminolevulinic acid or in untreated leaves subjected to repeated flashes of low intensity. [less ▲]

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See detail5-(Diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide : Synthesis and Evaluation of Spin Trapping Properties
Roubaud, Valérie; Mercier, Anne; Olive, Gilles ULg et al

in Journal of the Chemical Society. Perkin Transactions 2 (1997), 9

A new spin trap, the 5-(diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide (3), is prepared through a four-step synthetic route. The in vitro spin trapping properties of 3 have been ... [more ▼]

A new spin trap, the 5-(diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide (3), is prepared through a four-step synthetic route. The in vitro spin trapping properties of 3 have been investigated and the hydroxyl and superoxide spin adducts characterised. The persistence of the superoxide spin adduct obtained with 3 is compared with those of the analogues obtained with DEPMPO [5-(diethoxyphosphoryl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide] and DMPO in both phosphate buffer and pyridine. In 0.1 M phosphate buffer at pH 7.0, the HOO-3? adduct is found to be 2.8 times more persistent than HOO-DMPO?, but 5.7 times less than HOO-DEPMPO?. In phosphate buffer, HOO-3? decomposes to give HO-3?. The stereoselectivity of the addition of free radicals on 3 is generally poor, and mixtures of diastereomers have been observed by EPR. The overall spin trapping behaviour of nitrone 3 is more similar to that of DMPO than that of DEPMPO. [less ▲]

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See detailUse Of Mycosphaerella Fijiensis Toxins For The Selection Of Banana Cultivars Resistant To Black Leaf Streak
Harelimana, Germain; Lepoivre, Philippe ULg; Jijakli, Haissam ULg et al

in Euphytica : International Journal of Plant Breeding (1997), 96(1), 125-128

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See detailLes attitudes de jeunes Européens à l’égard de l’école et du cours d’éducation physique
Delfosse, Catherine; Ledent, Maryse; Carreiro da Costa, Francisco et al

in Sport (1997), 159/160

L'essentiel de la vie quotidienne des jeunes scolarisés s'organise entre le temps passé à l'école et des activités dites de loisirs. Une différence fondamentale sépare les deux domaines. Le premier, par ... [more ▼]

L'essentiel de la vie quotidienne des jeunes scolarisés s'organise entre le temps passé à l'école et des activités dites de loisirs. Une différence fondamentale sépare les deux domaines. Le premier, par son caractère obligatoire, concerne tous les enfants. Le second relève davantage du niveau social, économique et culturel des parents et nécessite une organisation familiale parfois complexe. On peut affirmer que tous les enfants ne disposent pas de chances égales de s'engager dans une pratique sportive organisée ou non organisée. ... [less ▲]

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See detailSite-directed mutagenesis of glutamate 166 in two beta-lactamases. Kinetic and molecular modeling studies.
Guillaume, Gilliane; Vanhove, M; Lamotte-Brasseur, J et al

in Journal of Biological Chemistry (1997), 272(9), 5438-44

The catalytic pathway of class A beta-lactamases involves an acyl-enzyme intermediate where the substrate is ester-linked to the Ser-70 residue. Glu-166 and Lys-73 have been proposed as candidates for the ... [more ▼]

The catalytic pathway of class A beta-lactamases involves an acyl-enzyme intermediate where the substrate is ester-linked to the Ser-70 residue. Glu-166 and Lys-73 have been proposed as candidates for the role of general base in the activation of the serine OH group. The replacement of Glu-166 by an asparagine in the TEM-1 and by a histidine in the Streptomyces albus G beta-lactamases yielded enzymes forming stable acyl-enzymes with beta-lactam antibiotics. Although acylation of the modified proteins by benzylpenicillin remained relatively fast, it was significantly impaired when compared to that observed with the wild-type enzyme. Moreover, the E166N substitution resulted in a spectacular modification of the substrate profile much larger than that described for other mutations of Omega-loop residues. Molecular modeling studies indicate that the displacement of the catalytic water molecule can be related to this observation. These results confirm the crucial roles of Glu-166 and of the "catalytic" water molecule in both the acylation and the deacylation processes. [less ▲]

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See detailComment se développe le savoir-lire ?
Hindryckx, Geneviève ULg; Lafontaine, Annette ULg

in Point sur la Recherche en Education (Le) (1997), 4

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See detailGlucose metabolism during bovine preimplantation development: analysis of gene expression in single oocytes and embryos.
Lequarré, Anne-Sophie ULg; Grisart, B.; Schuurbiers, N. et al

in Molecular Reproduction and Development (1997), 48(2), 216-26

Glucose metabolism of the bovine embryo is low during the first cleavages and increases sharply after the major resumption of the genome (8-16 cells). The mRNA level for genes involved in glucose ... [more ▼]

Glucose metabolism of the bovine embryo is low during the first cleavages and increases sharply after the major resumption of the genome (8-16 cells). The mRNA level for genes involved in glucose metabolism was tested by RT-PCR on individual oocytes and embryos at different stages of development. These genes were: glucose transport GLUT-1, hexokinase (HK), glucose-6-phosphatase-dehydrogenase (G6PDH), and glucose-phosphate-isomerase (GPI); actin was used as a reference transcript. RT-PCR results revealed three types of oocytes or embryos: positive with a PCR signal for each transcript considered, nul with no signal for any transcript, and heterogeneous with a PCR signal for some transcripts and none for others. The number of nul and heterogeneous samples was higher for slow than for fast-cleaving embryos (81% vs. 36%), and the proportion of positive embryos increased significantly at the 16-cell and morula stages (P < 0.002), suggesting a correlation between mRNA content and developmental capacity. In positive embryos, GLUT-1 level was reduced by half during maturation and fertilization. Actin and hexokinase mRNA levels decreased during the first cleavages, but significantly increased at the 16-cell and morula stages, respectively. GPI transcript remained stable throughout development, whereas there was a significant rise for G6PDH at the 4-cell stage, perhaps due to a polyadenylation process. Finally, the absence or decrease in intensity of several transcripts at the blastocyst stage suggests suboptimal culture conditions. [less ▲]

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See detailLes jeunes, leur activité physique et leurs perceptions de la santé, de la forme, des capacités athlétiques et de l’apparence
Ledent, Maryse; Cloes, Marc ULg; Piéron, Maurice

in Sport (1997), 159/160

La perception de sa propre compétence exerce un rôle primordial dans la décision de pratiquer une activité physique. La continuité d'une pratique résulte notamment d'un niveau de compétence jugé suffisant ... [more ▼]

La perception de sa propre compétence exerce un rôle primordial dans la décision de pratiquer une activité physique. La continuité d'une pratique résulte notamment d'un niveau de compétence jugé suffisant. A partir de 12 ans, les jeunes sont capables d'évaluer leur compétence et de faire la distinction entre cette dernière et l'effort déployé dans la performance réalisée. ... [less ▲]

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See detailMiospores from the type locality of the Middle Famennian Esneux Formation in the Ourthe Valley, eastern Belgium
Loboziak, S.; Avkhimovitch, V.I.; Streel, Maurice ULg

in Annales de la Société Géologique de Belgique (1997), 119(2), 111-118

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See detailVieillissement normal, démence d'Alzheimer et mémoire de travail
Van der Linden, Martial ULg; Collette, Fabienne ULg; Andrès Bénito, Pilar

in Psychologie Française (1997), 42

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See detailEtude clinique et anatomopathologique de l'infection expérimentale de lapins par une souche virale amyxomateuse isolée en Belgique
Marlier, Didier ULg; Coignoul, Freddy ULg; Boucraut-Baralon, Corine et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailTrace metal transfers between water and sediment in a freshwater system. Influence of microbial activity
Hambuckers-Berhin, Françoise; Hambuckers, Alain ULg; Remacle, Jean

in Studies in Environmental Science (1997), 68(353-368),

The purpose of our work was to determine, in a freshwater batch system, the importance and the direction of trace metal transfers between sediment and water as influenced by bacterial activity. Sediment ... [more ▼]

The purpose of our work was to determine, in a freshwater batch system, the importance and the direction of trace metal transfers between sediment and water as influenced by bacterial activity. Sediment was incubated in Meuse water in different conditions. Net transfer occurred on an average from sediment to water for Co, Cs, Cr, Cu, Hg, La, Ni, Zn and from water to sediment for Bi, Cd, Pb, Sb, Tl. Positive correlations between oxygen consumption and transfer of nine metals from sediment to water demonstrate the influence of bacterial activity. Correlations of the metal transfer either with water pH or with the variation of sediment weight at the end of incubation led to suppose that the alteration of the chemical conditions also strongly influenced the transfers. It was confirmed by the comparison of chemical characteristics of the water and of the sediment at the end of incubation in contrasted conditions. The uptake of 12 metals by a bacterial community isolated from the sediment was related to metal concentrations in the water. The specific transfer from the water to the bacterial biomass was appraised in the sediment incubation experiments. It allowed to compute the net metal transfer of 12 metals from the sediment to the water with significant bacterial activity. The comparison of these values with the transfers occurring at 4°C, i.e. with reduced bacterial activity, demonstrated that the transfer of 11 metals from the sediment to the water is clearly enhanced by bacterial activity. [less ▲]

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See detailImprovement Of Lipase Production From Yarrowia Lipolytica
Destain, Jacqueline ULg; Weber, D.; Thonart, Philippe ULg

in Biotechnology Letters (1997), 19(2),

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See detailGlobal adaptive stabilization of cascade nonlinear systems
Jankovic, M.; Sepulchre, Rodolphe ULg; Kokotovic, Petar V.

in Automatica (1997), 33(2), 263-368

An adaptive controller is developed for a class of nonlinear systems for which other approaches (e.g. backstepping) may fail to be applicable. The new design employs feedback passivation and an explicit ... [more ▼]

An adaptive controller is developed for a class of nonlinear systems for which other approaches (e.g. backstepping) may fail to be applicable. The new design employs feedback passivation and an explicit construction of a Lyapunov function for the zero dynamics with respect to a relative degree 1 output. As an illustration a longstanding "nonlinear benchmark problem" is solved. [less ▲]

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See detailErythromycin as a tool to investigate the tetrapyrrole biosynthetic pathways in habituated and normal sugarbeet calli
Bisbis, B.; Kevers, Claire ULg; Huault, C. et al

in Plant Growth Regulation (1997), 23(3), 147-152

Erythromycin (ERT) has been shown to reduce the 5-aminolevulinic acid (ALA) synthesizing capacity of a normal (N) chlorophyllous sugarbeet callus, grown under light, in contrast to a habituated ... [more ▼]

Erythromycin (ERT) has been shown to reduce the 5-aminolevulinic acid (ALA) synthesizing capacity of a normal (N) chlorophyllous sugarbeet callus, grown under light, in contrast to a habituated achlorophyllous nonorganogenic (HNO) callus of the same species. Similar effects were obtained on total hemes and on catalase which is a hemoprotein used as marker. The effect of ERT, which is an inhibitor of plastid differentiation and of chlorophyll synthesis, was reversed in the N callus by a supply of glycine and succinate. The compounds are the precursors of ALA synthesized through 5-aminolevulinic acid synthase (ALAS) which is implied in the Shemin pathway. The involvement of ALAS appeared to be favoured when plastids were undifferentiated (HNO callus) or when plastids were inefficient (N callus under darkness or under light after ERT treatment). [less ▲]

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See detailPsychiatrie de liaison:regards sur une pratique de la psychologie médicale en hôpital général
Triffaux, Jean-Marc ULg

in Revue francaise de psychiatrie et de psychologie médicale (1997)

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See detailEffect of n-3 fatty acids in Eurasian perch broodstock diet on egg fatty acid composition and larva stress resistance.
Abi-Ayad, Amine; Mélard, Charles ULg; Kestemont, Patrick

in Aquaculture International (1997), 5

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See detailSurveys of ultraviolet-excess quasar candidates in large fields
Gosset, Eric ULg; Moreau, O.; Surdej, Jean ULg et al

in Astronomy and Astrophysics. Supplement Series (1997), 123

We describe the results of a survey for moderately bright quasars performed in a 20.6-square-degree field around the galaxy NGC 450. The quasar candidates were selected on the basis of their ultraviolet ... [more ▼]

We describe the results of a survey for moderately bright quasars performed in a 20.6-square-degree field around the galaxy NGC 450. The quasar candidates were selected on the basis of their ultraviolet excess: by comparative visual inspection of the double image of each single object on a U/B dual-exposure Schmidt photographic plate, 95 primary and 45 secondary quasar candidates were selected on the basis of their $U$ image being too bright. The spectroscopic identification of the primary candidates led to the discovery of 59 bona fide quasars (out of which 6 were previously known). The Palomar Schmidt plate was digitised using the MAMA measuring machine and the outcoming data reduced using ad hoc procedures. A photometric calibration allowed us to derive values for the limiting magnitudes and for the U-B index selection threshold of the survey. A catalogue containing 60 quasars is presented with accurate positions, magnitudes and additional information such as redshifts. We studied the spatial distribution of the objects and detected, for the quasars of our sample, a significant deviation from randomness in the form of a propensity to cluster in pairs on the celestial sphere with a typical scale of about 10 arcmin. We also formally detected a tendency towards a 3-D clustering, but this result is induced by a single pair of quasars. A forthcoming paper will deal with a similar work performed in a field around NGC 520; the latter field is located directly to the North of the present one and slightly overlaps it. Based on observations acquired at the Mount Palomar and Las Campanas Observatories as well as at the European Southern Observatory. Also based on Schmidt-plate digitisations performed with the MAMA measuring machine of C.A.I. (I.N.S.U., Paris). [less ▲]

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See detailRadiographical Assessment of Interphalangeal Rotation in the Evaluation of Equine Digital Conformation
Caudron, I.; Grulke, Sigrid ULg; Gabriel, Annick ULg et al

in Acta Anatomica (1997), 160(2), 95-9

This study is a part of a work to design a radiographical method to objectively define the conformation of an equine digit and to assess the individual appropriate trimming of a horse. Various angles were ... [more ▼]

This study is a part of a work to design a radiographical method to objectively define the conformation of an equine digit and to assess the individual appropriate trimming of a horse. Various angles were measured directly from the phalangeal bones. The authors observed that the bone relief of the sesamoid ligament insertions on the proximal phalanx was an essential landmark to determine the phalangeal alignment. The same angles were measured from specific radiographs and made it possible to quantify the rotation imposed to the proximal phalanx. The authors also noticed that the phalangeal rotation had little influence on the radiographic image of articular asymmetry. [less ▲]

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See detailLe rôle de l'officier de l'état civil requis de célébrer un mariage présumé simulé
Paris, Catherine ULg

in Revue Trimestrielle de Droit Familial (1997)

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See detailEffet des langues hybrides parentales sur la phonologie et la métaphonologie d’enfants d’origine italienne
Lucchini, Silvia ULg

in Revue de psychologie de l'éducation (1997), (3), 9-32

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See detailAnaemia of lung cancer is due to impaired erythroid marrow response to erythropoietin stimulation as well as relative inadequacy of erythropoietin production.
Dowlati, A.; R'Zik, Samir ULg; Fillet, Georges ULg et al

in British Journal of Haematology (1997), 97(2), 297-9

Many studies have been done in order to elucidate the pathogenesis of the anaemia of chronic disorders accompanying cancer, with conflicting results. This is probably due to the heterogeneity of the ... [more ▼]

Many studies have been done in order to elucidate the pathogenesis of the anaemia of chronic disorders accompanying cancer, with conflicting results. This is probably due to the heterogeneity of the patient population selected for these studies (many patients treated by chemotherapy). To avoid this pitfall, in this study a very homogenous group of chemotherapy and radiotherapy-naive patients with lung cancer were selected. Serum erythropoietin and soluble transferrin receptor measurements suggested that the anaemia of non-treated lung cancer is mainly due to an impaired erythroid marrow response to erythropoietin stimulation. However, a relative inadequacy of erythropoietin production may also contribute. [less ▲]

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See detailFunctional anatomy of verbal and visuospatial span tasks in Alzheimer's disease
Collette, Fabienne ULg; Salmon, Eric ULg; Van der Linden, Martial ULg et al

in Human Brain Mapping (1997), 5(2), 110-118

The aim of the study was to emphasize cerebral regions which subserve the performance of short-term memory tasks in patients with Alzheimer's disease. We correlated scores obtained on span tasks with ... [more ▼]

The aim of the study was to emphasize cerebral regions which subserve the performance of short-term memory tasks in patients with Alzheimer's disease. We correlated scores obtained on span tasks with cerebral metabolism measured at rest with positron emission tomography. Scores obtained on the digit span task correlated with glucose metabolism in a brain area centered on the premotor cortex and extending to the adjacent motor and parietal gyri. There exists some evidence suggesting that this area may subserve the sequential organization of material stored in short-term memory. In a secondary analysis, we also observed significant interregional correlations between left-sided brain areas which are part of the neural network subserving verbal working memory processes in healthy controls. These data suggest that individual performance on verbal span tasks in AD patients may essentially depend on the preservation of their ordination processing capacity. The absence of correlation with prefrontal regions suggests that AD patients might not spontaneously engage central executive resources to reach their maximal span score. For simultaneous visuospatial span task, the performance of patients correlated with posterior brain regions, and not with prefrontal cortices. Hum. Brain Mapping 5:110-118, 1997. © 1997 Wiley-Liss Inc. [less ▲]

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See detailElementverteilung in einem moorprofil (Präboreal bis subatlantikum) im Tal der Helle/Hill (Hohes Venn, Belgien)
Gaida, R.; Olbrechts, S.; Hindryckx, Marie-Noëlle ULg et al

in Geoökodynamik (1997), XVIII(2/3), 79-90

This investigation was on the distribution of some elements (Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Ni, Pb, Zn) in a groundwater bog in the Helle/Hill valley in the Hohes Venn, Belgium. The thickness of the ... [more ▼]

This investigation was on the distribution of some elements (Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Ni, Pb, Zn) in a groundwater bog in the Helle/Hill valley in the Hohes Venn, Belgium. The thickness of the deposit is 155 cm. This bog has developed since the Pre Boreal period. The distribution in the lower part of the bog profile is very strongly influenced by water from the adjacent slope which is characterised by a high content of different metals. This resulted in a significant amount of Fe, Ni and Zn and to a lesser degree of Cu and Cd. The metals stem from ore which originated from the nearby Hill valley tonalite. The weathering of the sulphidic ore created sulphuric acid which is responsible for the low pH values of the peat samples. Not only the influence of the local geology and mineralogy is discussed, but also the behaviour of different plants with respect to element uptake and accumulation. Atmospheric input also has an influence, especially on the distribution of the elements in the upper part of the profile. [less ▲]

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See detailRyle et la phénoménologie
Leclercq, Bruno ULg

in Recherches Husserliennes (1997), 7

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See detailUsefulness of 18fdg Positron Emission Tomography in Detection and Follow-up of Digestive Cancers
Paulus, P.; Hustinx, Roland ULg; Daenen, Frédéric ULg et al

in Acta Gastro-Enterologica Belgica (1997), 60(4, Oct-Dec), 278-80

PET is a diagnostic method that creates high resolution, 3 dimensional tomographic images of the distribution of positron emitting radionuclides in the human body. Recent technological developments allow ... [more ▼]

PET is a diagnostic method that creates high resolution, 3 dimensional tomographic images of the distribution of positron emitting radionuclides in the human body. Recent technological developments allow the use of whole-body PET devices in clinical oncology. 18FDG is a glucose analog transported and competitively used with glucose reflecting the increased glucose metabolism into malignant cells. Differential diagnosis between chronic pancreatitis and pancreatic cancer is already a well-documented indication. For initial staging of gastro-esophageal and colorectal tumours, results are preliminary but the clinical impact seems to be rather limited. At present, the major indication of FDG-PET is the detection and staging of colorectal cancer recurrences. FDG-PET allows the differentiation between scared tissue and tumour when structural imaging is often confusing. In the same time, the whole-body imaging capability provides unique information that can modify loco-regional and liver staging. Overall, FDG-PET affects the clinical management of 30 to 40% of these patients. Quantitative assessment of therapeutic response to chemotherapy regimen appears to be one of the most promising applications of FDG-PET. Since the most effective therapy of colorectal cancer are often surgical, the role of chemotherapy in colorectal cancer remains limited to adjuvant therapy and in advanced disease. However, FDG-PET could be of great value in assessing the response of oesophageal carcinomas to chemo-radio therapy, before surgery. In our experience, FDG-PET appears to be the first line diagnostic method in the detection and staging of colorectal recurrence and differential diagnosis of pancreatic tumour versus chronic pancreatitis. [less ▲]

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See detailVerapamil, a phenylalkylamine Ca2+ channel blocker, inhibits ATP-sensitive K+ channels in insulin-secreting cells
Lebrun, P.; Antoine, M.-H.; Ouedraogo, R. et al

in Diabetologia (1997), 40

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See detailLangmuir film balance study of the surface properties of a soluble fraction of milk fat-globule membrane
Innocente, N.; Blecker, Christophe ULg; Deroanne, C. et al

in Journal of Agricultural and Food Chemistry (1997), 45(5), 1559-1563

Viewed from its origin, composition, and physicochemical properties, milk fat-globule membrane (MFGM) appears to act as a good, natural emulsifier and should be also considered as a potential stabilizing ... [more ▼]

Viewed from its origin, composition, and physicochemical properties, milk fat-globule membrane (MFGM) appears to act as a good, natural emulsifier and should be also considered as a potential stabilizing agent in the preparation of certain foods, e.g. creams and emulsions, infant formulas, and reduced-fat products. The present work was undertaken in an attempt to gain further information on the physicochemical properties of MFGM. In particular, the purpose of this study was to determine surface properties of a soluble fraction of MFGM (SFMFGM) using a film balance and to investigate the changes in the surface activity at different temperatures, which may occur during milk cream ripening or during heat and mechanical treatments of dairy products. The results showed that film balance measurements at the air/water interface actually provided a useful method for the study of SFMFGM monolayers. It was deduced from the compression isotherms that the SFMFGM films spread at the air/water interface presented a different behavior when the temperature varied from 4 to 40 degrees C. [less ▲]

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See detailFast and slow tracks in lysozyme folding: Insight into the role of domains in the folding process
Matagne, André ULg; Radford, S. E.; Dobson, C. M.

in Journal of Molecular Biology (1997), 267(5), 1068-1074

The folding of lysozyme involves parallel events in which hydrogen exchange kinetics indicate the development of persistent structure at very different rates. We have monitored directly the kinetics of ... [more ▼]

The folding of lysozyme involves parallel events in which hydrogen exchange kinetics indicate the development of persistent structure at very different rates. We have monitored directly the kinetics of formation of the native molecule by the binding of a fluorescently labelled inhibitor, MeU-diNAG (4-methylumbelliferyl-N,N'-diacetyl-beta-D-chitobioside). The data show that native character monitored in this way also develops with different timescales. Although the rate determining step on the slow pathway (similar to 75% of molecules at pH 5.5, 20 degrees C) can be attributed to the need to reorganise structure formed early in the folding process, the data indicate that the rate determining step on the fast track (involving similar to 25% of molecules) involves the docking of the two constituent domains of the protein. In the fast folding track the data are consistent with a model in which each domain forms persistent structure prier to their docking in a locally cooperative manner on a timescale comparable to the folding of small single domain proteins. (C) 1997 Academic Press Limited. [less ▲]

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See detailThe meaning of formal: from weak to strong formal methods
Wolper, Pierre ULg

in International Journal on Software Tools for Technology Transfer (1997), 1(1-2), 6--8

This short note reflects on what makes formal methods "formal". It concludes that there are weak and strong ways of being formal, the latter being linked to the formality of the method being exploitable ... [more ▼]

This short note reflects on what makes formal methods "formal". It concludes that there are weak and strong ways of being formal, the latter being linked to the formality of the method being exploitable, and exploited, in software tools. [less ▲]

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See detailPratique et importance des principales activités de loisirs chez des jeunes de 12 et 15 ans dans cinq pays européens
Cloes, Marc ULg; Ledent, Maryse; Didier, Pascale et al

in Sport (1997), 159/160

On admet généralement que les loisirs sont devenus une expression du style de vie dans les pays industrialisés. Dans ce contexte, la place qu'ils occupent dans le secteur social et dans le monde ... [more ▼]

On admet généralement que les loisirs sont devenus une expression du style de vie dans les pays industrialisés. Dans ce contexte, la place qu'ils occupent dans le secteur social et dans le monde économique semble croître régulièrement. Les comparaisons interculturelles des activités de loisirs s'avèrent très difficiles en raison des différences enregistrées dans la conception des instruments utilisés dans les enquêtes et dans les intérêts des équipes de recherche. ... [less ▲]

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See detailA moderate transfusion regimen may reduce iron loading in beta-thalassemia major without producing excessive expansion of erythropoiesis.
Cazzola, M.; Borgna-Pignatti, C.; Locatelli, F. et al

in Transfusion (1997), 37(2), 135-40

BACKGROUND: Hypertransfusion with a baseline hemoglobin of 10 to 12 g per dL is still considered by many to be the mainstay of conservative therapy for beta-thalassemia major. However, this regimen is ... [more ▼]

BACKGROUND: Hypertransfusion with a baseline hemoglobin of 10 to 12 g per dL is still considered by many to be the mainstay of conservative therapy for beta-thalassemia major. However, this regimen is frequently associated with manifestations of transfusion iron overload, despite regular chelation therapy with subcutaneous desferoxamine. STUDY DESIGN AND METHODS: To verify whether a transfusion regimen with a target pretransfusion hemoglobin level between 9 and 10 g per dL can allow a significant reduction in blood consumption, while still effectively suppressing erythropoiesis, the records were reviewed of 32 beta-thalassemia major patients, who were maintained at a pretransfusion hemoglobin of 11.3 +/- 0.5 g per dL between 1981 and 1986. These patients were switched at the beginning of 1987 to a transfusion regimen with pretransfusion hemoglobin of 9.4 +/- 0.4 g per dL. The degree of erythroid marrow activity was evaluated in these patients and in 32 subjects with beta-thalassemia intermedia through the simple measurement of serum transferrin receptor. RESULTS: After the adoption of the moderate transfusion regimen, transfusion requirements decreased from 137 +/- 26 to 104 +/- 23 mL per kg per year of red cells (p < 0.0001), and mean serum ferritin decreased from 2448 +/- 1515 to 1187 +/- 816 micrograms per L (p < 0.0001), with one-half of patients achieving serum ferritin levels lower than 1000 micrograms per L. The proportion of patients having spontaneous pubertal development increased significantly (p < 0.01), as a result of less iron-related gonadotropin insufficiency. At the lower pretransfusion hemoglobin, erythroid marrow activity did not exceed two to three times normal levels in most subjects. CONCLUSION: As compared with hypertransfusion, moderate transfusion may allow more effective prevention of iron loading, with higher likelihood of spontaneous pubertal development and without producing excessive expansion of erythropoiesis. [less ▲]

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See detailLes antidotes en Médecine Vétérinaire
Delaunois, A.; Plume, Ch; Ansay, M. et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailQtl Mapping to Qtl Cloning: Mice to the Rescue
Georges, Michel ULg

in Genome Research (1997), 7(7), 663-665

With the availability of dense, highly informative marker maps, it has recently become feasible to map genes (Quantitative Trait Loci or QTL) accounting for part of the heritability of continuously ... [more ▼]

With the availability of dense, highly informative marker maps, it has recently become feasible to map genes (Quantitative Trait Loci or QTL) accounting for part of the heritability of continuously distributed traits in experimental crosses as well as outbred populations. QTL mapping efforts have almost invariably revealed a limited number of loci with effects of a magnitude clearly departing from the predictions of the infinitesimal model (a model introduced to facilitate mathematical treatment of quantitative traits rather than to truly reflect their underlying biology). As most experimental designs would have limited detection power, which could lead to an overestimation of the identified gene effects, interpretation of results from QTL mapping studies must be viewed with caution. However, numerous independent confirmation studies leave little doubt that most quantitative traits indeed involve a limited suite of loci with major effect. This assertion seems to hold not only for QTL mapped in crosses between divergent lines, but—more importantly—for QTL segregating in outbred populations as well (for review, see Paterson 1995). Despite the sometimes unexpected magnitude of the identified QTL effects, the lack of simple correspondence between genotype and phenotype in complex trait analysis precludes the unambiguous identification of recombinant individuals. This may limit the achievable mapping resolution of QTL, posing a serious threat to the efficacy of positional (candidate) cloning for QTL considerably. QTL mapping efforts, whether performed in pedigrees or by exploiting linkage disequilibrium, are likely to leave geneticists with a portion of the genome that contains tens if not hundreds of genes and many DNA sequence polymorphisms to examine to identify the causal variant. Mutations causing monogenic inherited diseases are often destructive enough to leave little doubt about their causality. Even if the functional consequences of such mutations were less transparent, demonstration of a perfect correspondence between genotype and … [less ▲]

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See detailThe faint young sun climatic paradox: Influence of the continental configuration and of the seasonal cycle on the climatic stability
Longdoz, Bernard; François, Louis ULg

in Global and Planetary Change (1997), 14(3-4), 97-112

A quasi-three-dimensional climate model is used to study the early state of the Earth when the solar luminosity was 70% of the present value, Usually, climatic simulations going back to this period lead ... [more ▼]

A quasi-three-dimensional climate model is used to study the early state of the Earth when the solar luminosity was 70% of the present value, Usually, climatic simulations going back to this period lead to a completely frozen planet contrasting with the geologic evidences of sedimentary rock formation and thus of the presence of liquid water at the surface of the continents during the Archean (4.6-2.5 billion years before present). Here, several model simulations are performed for solar luminosities varying between 0.7 and 1 times the present value. Using the present-day continental configuration and taking the seasonal cycle into account, a steady state is found in which glaciation is complete but snow covers only some oceanic coasts, leaving the continents essentially snow-free. As a result, the albedo of the continental area is strongly reduced compared to that of the frozen ocean, Some continental temperatures can almost reach the freezing point of water in summer (-1 degrees C in the center of Eurasia). This result can be explained by the behavior of the detailed hydrologic cycle included in the model. During the decrease of the solar luminosity, the jump to a completely frozen Earth occurs when the solar luminosity reaches 0.86 times its present value. The behavior of the climatic system is substantially different with a global ocean configuration. In the absence of land surfaces, the meridional heat transport, explicitly calculated, is less effective and the glaciation of a model latitude zone does not lead to the glaciation of its equatorward neighbor. The climate instability is relatively local and the jump to the completely frozen state is much more progressive than in the case of the modem continental configuration. The role of the seasonal cycle in the paleoclimatic simulation is also studied. Due to the non-linearity of the model, removing the seasonal cycle drives the system to an increase of the annual mean planetary albedo and to a decrease of the relative value (0.82) of the critical solar luminosity at which the jump to the completely frozen solution occurs. [less ▲]

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See detailBeam-laser measurements and relativistic Hartree-Fock calculations of the lifetimes of the 4d95p levels in Ag II
Biémont, Emile ULg; Pinnington, E. H.; Kernahan, J. A. et al

in Journal of Physics : B Atomic Molecular & Optical Physics (1997), 30

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See detailRésumé des communications et livret guide des excursions
Petit, François ULg; Wastiaux, Cécile; Assani, Ali Arkamose et al

in Journées hydrologiques françaises (Commission des Hydrosystèmes fluviaux) Journées de terrain organisées en Ardenne et dans les Hautes fagnes (1997)

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See detailDiagenetic and paleogeographic significance of clay and other sedimentary components in the middle Devonian limestones of Western Ardennes, France
Chamley, H.; Proust, J. N.; Mansy, J. L. et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (1997), 129

Givetian deposits accumulated in a more than 300-m-thick succession on a carbonate platform developed on the passive margin of the so-called Rheic ocean. These rocks crop out in the Ardenne massif at ... [more ▼]

Givetian deposits accumulated in a more than 300-m-thick succession on a carbonate platform developed on the passive margin of the so-called Rheic ocean. These rocks crop out in the Ardenne massif at Glageon in a structural context marked by small fault-controlled basins subjected to moderate overburden, tectonic and metamorphic constraints. Data on the clay mineral distribution, associated with detailed information on limestone facies/microfacies, as well as data on the depositional profile and sequence stratigraphic evolution of these rocks indicate strong carbonate diagenesis and moderate clay diagenesis, the latter being favoured by the early occurrence of the former, which prevented further fluid-rock interaction. The clay assemblage distribution, which roughly parallels the palaeomorphologic and palaeobathymetric shape of the Givetian continental margin, is organized in five successive zones indicating large-scale sequence stratigraphic evolution and the control of regional sea-level fluctuations. The clay and other sedimentary components provide additional information on the warm and variably humid climate, northern, relative to southern, terrigenous sources, the open sea relative to restricted depositional environments, the temporary tectonic rejuvenation of the continental hinterland and the chemical conditions allowing early diagenetic modifications. [less ▲]

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See detailChanges in the Distribution Pattern of Galectin-1 and Galectin-3 in Human Placenta Correlates with the Differentiation Pathways of Trophoblasts
Maquoi, Erik ULg; van den Brule, F. A.; Castronovo, Vincenzo ULg et al

in Placenta (1997), 18(5-6, Jul-Aug), 433-9

Human placentation is a complex biological phenomenon that results from precisely regulated interactions between cells and the extracellular matrix. Galectin- 1 and galectin-3 belong to a newly defined ... [more ▼]

Human placentation is a complex biological phenomenon that results from precisely regulated interactions between cells and the extracellular matrix. Galectin- 1 and galectin-3 belong to a newly defined family of galactose-binding lectins that can bind several glycoconjugates such as the basement membrane glycoprotein laminin, and are involved in many biological events including cell adhesion. In this study, the expression of these two galectins in first and third trimester normal human placenta was examined using single and double immunohistochemical staining and specific antibodies for galectins and cytokeratins. Galectin-3 was detected in all trophoblastic lineages including villous cytotrophoblasts and extravillous trophoblasts (trophoblastic cell columns, infiltrating trophoblasts, endovascular trophoblasts and placental bed giant cells). On the contrary, galectin-1 distribution was restricted to endometrium. A reduction of galectin-3 expression was observed from the villous trophoblasts to the trophoblastic cell columns. This pattern correlated with the switch from a proliferative to a migratory phenotype. Galectin-1 and galectin-3 were both detected in maternal decidual cells. Our data demonstrate a specific pattern of galectin-1 and galectin-3 expression in trophoblastic tissue, and suggest these lectins could contribute to cell-cell and cell matrix interactions of trophoblast during placentation. [less ▲]

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See detailCertification in the meat channel.
Mortiaux, Frédéric; Renaville, Robert ULg; Gengler, Nicolas ULg et al

in Journal of Animal Science (1997), 75(1), 136

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See detailEffects of level of intake and of available volatile fatty acids on the absorptive capacity of sheep rumen
Doreau, Michel; Ferchal, Edwin; Beckers, Yves ULg

in Small Ruminant Research (1997), 25

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See detailPhénomènes karstiques dans les roches plutoniques et métamorphiques du sud Cameroun
Vicat, Jean-Paul; Lips, Bernard; Pouclet, André et al

in Karstologia (1997), 29

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See detail125I-Tyr0-hCRH labelling characteristics of corticotropin-releasing hormone receptors: differences between normal and adenomatous corticotrophs.
Abs, R.; Smets, G.; Vauquelin, G. et al

in Neurochemistry International (1997), 30(3), 291-297

The presence of corticotropin-releasing hormone (CRH) receptors has been previously demonstrated in corticotrophs from normal pituitaries using a method combining immunocytochemistry and liquid emulsion ... [more ▼]

The presence of corticotropin-releasing hormone (CRH) receptors has been previously demonstrated in corticotrophs from normal pituitaries using a method combining immunocytochemistry and liquid emulsion autoradiography. The aim of this study was to compare the characteristics of the 125I-Tyr0-hCRH binding in corticotrophs from normal pituitaries (three obtained at autopsy and one obtained at surgery) with corticotrophs from pituitary adenomas (six corticotroph adenomas responsible for Cushing's disease and two silent corticotroph adenomas secreting a biologically inactive ACTH molecule). In normal corticotrophs, the larger part of the 125I-Tyr0-hCRH binding was localised in patchy conglomerates at the centre of the cell and, to a much lesser degree, in a diffuse pattern at the cell periphery. In adenomatous corticotrophs, CRH receptor expression is disturbed both quantitatively and qualitatively. Except for a minority of cells in one adenoma, all adenomatous corticotrophs showed only peripherally bound 125I-Tyr0-hCRH and no centrally localised binding. Furthermore, adenomatous corticotrophs revealed a statistically significant lower signal intensity when compared to normal corticotrophs and a strongly negative correlation was found between the labelling area in adenomatous corticotrophs and both the basal and CRH-stimulated plasma ACTH levels. These findings suggest defective processing of CRH receptors and could be relevant to the sustained ACTH secretion by adenomatous corticotrophs in Cushing's disease and, more generally, provide an explanation to its pathology. The silent corticotrophs secreting a biologically inactive ACTH molecule were characterised by a very faint signal intensity, although present on almost every cell. [less ▲]

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See detailThe lowest 5g-6h supermultiplet of Fe II
Biémont, Emile ULg; Johansson, S.; Palmeri, P.

in Physica Scripta (1997), 55

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See detailMultiple pregnancy-associated glycoproteins are secreted by day 100 sheep placenta
Xie, Sancai; Green, Jonathan; Bao, Bagna et al

in Biology of Reproduction (1997), 57(6), 1384-1393

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep ... [more ▼]

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep and other ruminants produce similar products. There is evidence, however, that these antigens, which are related structurally to the pepsinogens and other aspartic proteinases, are not single gene products but members of an extensive family. Here, the sequential use of ammonium sulfate precipitation and Sepharose blue, anion-exchange, and cation-exchange chromatographies, as well as isoelectric elution from a Mono P column, has allowed several PAG1-related molecules to be purified from the medium after culture of explants from Day 100 sheep placentas. Each of these PAGs cross-reacted to a varying extent with a panel of three different anti-PAG1 antisera. Four of them, all of which were major secretory products of the placenta, were subjected to amino-terminal microsequencing. Although each was related to ovine (ov) PAG1, none was identical. Reverse transcription-polymerase chain reaction was then used to amplify PAG1-related cDNA from Day 100 placental RNA. Seven novel full-length cDNA, all distinct from ovPAG1, were identified from 25 cDNA selected for sequencing. Only two of these (ovPAG3 and ovPAG7) encoded polypeptides identical in sequence at their inferred amino termini to one of the PAGs (ovPAG65) purified from explant cultures. Even so, they were only 84% identical in overall sequence. The remaining five cDNA were unique. In situ hybridization analysis revealed that expression of ovPAG3 and ovPAG7, like that of ovPAG1, is confined to trophoblast binucleate cells. The data confirm that at Day 100 of pregnancy the ovine placenta produces many different PAGs, which differ considerably in sequence and immunological cross-reactivity. [less ▲]

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See detailProcesses in regions of freshwater influence (ROFI)
Nihoul, Jacques ULg; Djenidi, Salim ULg; Huthnance, J. M. et al

in Journal of Marine Systems (1997), 12(1-4), 1-2

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See detailBicuculline methiodide potentiates NMDA-dependent burst firing in rat dopamine neurons by blocking apamin-sensitive Ca2+-activated K+ currents.
Johnson, S. W.; Seutin, Vincent ULg

in Neuroscience Letters (1997), 231(1), 13-6

Apamin, a bee venom toxin which blocks a Ca2+-dependent K+ current, potentiates N-methyl-D-aspartate (NMDA)-induced burst firing in dopamine neurons. We now report that burst firing is also potentiated by ... [more ▼]

Apamin, a bee venom toxin which blocks a Ca2+-dependent K+ current, potentiates N-methyl-D-aspartate (NMDA)-induced burst firing in dopamine neurons. We now report that burst firing is also potentiated by an apamin-like effect of bicuculline methiodide (BMI) at the same concentration (30 microM) which blocks GABA(A) receptors in vitro. Using microelectrodes to record intracellularly from rat dopamine neurons in the midbrain slice, BMI reduced the apamin-sensitive afterhyperpolarization in all cells tested. BMI also mimicked apamin (100 nM) by potentiating burst firing produced by a concentration of NMDA (10 microM) which is too low to evoke burst firing when perfused alone. When recording under voltage-clamp, both BMI and apamin reduced a depolarization-activated outward current which was also sensitive to perfusate containing no-added Ca2+. Although picrotoxin (100 microM) and bicuculline free base (30 microM) blocked the inhibition of firing produced by the GABA(A) agonist isoguvacine (100 microM), neither had apamin-like effects. We conclude that BMI potentiates burst firing by blocking an apamin-sensitive Ca2+-activated K+ current. [less ▲]

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See detailMultipole Transitions in Nicke-like and Palladium-like Spectra
Biémont, Emile ULg

in Journal of Physics : B Atomic Molecular & Optical Physics (1997), 30

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See detailFreeze-drying of lactic acid bacteria : Lactobacillus acidophilus
Desmons, S.; Zgoulli, S.; Destain, Jacqueline ULg et al

in Mededelingen - Faculteit Landbouwwetenschappen, Rijksuniversiteit Gent (1997), 62/4b

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See detailCrystallization and preliminary X-ray analysis of bacteriophage lambda lysozyme in which all tryptophans have been replaced by aza-tryptophans
Evrard, Christine ULg; Declercq, Jean-Paul; Fastrez, Jacques

in Acta Crystallographica Section D-Biological Crystallography (1997), D53

After many unsuccessful attempts to crystallize the bacteriophage lambda lysozyme, a mutant where all the tryptophan residues have been replaced by aza-tryptophans has been crystallized by the vapor ... [more ▼]

After many unsuccessful attempts to crystallize the bacteriophage lambda lysozyme, a mutant where all the tryptophan residues have been replaced by aza-tryptophans has been crystallized by the vapor-diffusion method. The crystals are orthorhombic and belong to space group P212121 with cell dimensions a = 73.01, b = 78.80, c = 82.31 Å. Diffraction data were collected using synchrotron radiation sources. Crystals diffract to a resolution of 2.3 Å. Data from two different platinum derivatives were also recorded to 2.8 and 2.5 Å, respectively. [less ▲]

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See detailA primal-dual approach in truss topology optimization
Beekers, M.; Fleury, Claude ULg

in Computers & Structures (1997), 64(1-4), 77-88

The objective of truss topology optimization is to find, for a given weight, the stiffest truss, defined as a subset of an initially choosen set of bars called the ground structure. The restrictions are ... [more ▼]

The objective of truss topology optimization is to find, for a given weight, the stiffest truss, defined as a subset of an initially choosen set of bars called the ground structure. The restrictions are bounds on bar volumes and the satisfaction of equilibrium equations. For a single load case and without bounds on bar volumes, the problem can be written as a linear programming problem with nodal displacements as variables. The addition to the objective function of a quadratic term vanishing at the optimum allows us to use a dual solution scheme. A conjugate gradient method is well suited to maximize the dual function. Several ground structures are introduced. For large networks, those where each node is connected to those situated in a certain vicinity give a good compromise between generating a reasonable number of bars and obtaining a sufficient number of possible directions. Some examples taken from the literature are treated to illustrate the quality of the solution and the influence of initial topology. (C) 1997 Civil-Comp Ltd and Elsevier Science Ltd. [less ▲]

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See detailDuplication of a vertebral artery associated with epidermoid cyst of the posterior fossa.
Weis, J.; Reul, J.; Mayfrank, L. et al

in European radiology (1997), 7(3), 412-4

A case of a duplication of the left vertebral artery associated with a premedullary epidermoid cyst at the level of the foramen magnum is described. The close proximity of the two malformative lesions in ... [more ▼]

A case of a duplication of the left vertebral artery associated with a premedullary epidermoid cyst at the level of the foramen magnum is described. The close proximity of the two malformative lesions in the present case and the overlap of the periods when such developmental abnormalities can arise suggest that they might be causally linked. [less ▲]

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See detailPrognostic factors in urothelial renal pelvis and ureter tumors: A multicenter Rare Cancer Network study
Ozsahin, Mahmut; Zouhair, Abderrahim; Villà, S. et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 3(2(supp)), 290

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See detailLe diagnostic de la reproduction: fertilité, gestation, anœstrus
Delahaut, Philippe; Sulon, Joseph ULg; Ectors, Francis et al

in Cahiers Agricultures (1997), 6

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See detailIn vivo behavior of poly(D,L)-lactide microspheres designed for chemoembolization
Flandroy, P.; Grandfils, Christian ULg; Danen, B. et al

in Journal of Controlled Release (1997), 44(2-3), 153-170

Although chemoembolization advantageously combines arterial embolization of the vascular supply of a neoplasm with controlled intra-arterial infusion of chemotherapeutic drug(s), its application is ... [more ▼]

Although chemoembolization advantageously combines arterial embolization of the vascular supply of a neoplasm with controlled intra-arterial infusion of chemotherapeutic drug(s), its application is limited by the lack of appropriate and reliable embolization materials. Recently, calibrated microspheres of poly(D,L)-lactide have proved to be promising in embolization. Nevertheless, repetitive chemoembolization requires the availability of microspheres degradable within a few days. For this purpose, microspheres consisting of a blend of two polyesters of a very different molecular weight (Mn =65 000 and 3500 in a 16:84 wt. ratio) have been prepared and injected in the renal arteries of rabbits. The in vivo fate of these two component microspheres has been compared by radiology and histology to microspheres prepared from the high molecular weight poly(D,L)-lactide. Furthermore, the in vivo degradation of the polymer has been measured by size exclusion chromatography after quantitative reextraction from the embolized kidney. Degradation kinetics has been compared to data previously reported in vitro. According to the observations performed during the in vivo study, the 50/50 microspheres appear more useful for the chemoembolization of tumors. [less ▲]

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See detailA bryological survey of the Brussels Capital Region (Belgium)
Vanderpoorten, Alain ULg

in Scripta Botanica Belgica (1997), 14

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See detailClinical characteristics, prognosis and treatment for pelvic cryptorchid seminoma
Li; COUCKE, Philippe ULg; Qian et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 38(2), 351-357

Purpose: To analyze the clinical characteristics, prognosis, and treatment outcome of pelvic cryptorchid seminoma (PCS), and to determine whether whole abdominal-pelvic irradiation for Stage I disease is ... [more ▼]

Purpose: To analyze the clinical characteristics, prognosis, and treatment outcome of pelvic cryptorchid seminoma (PCS), and to determine whether whole abdominal-pelvic irradiation for Stage I disease is necessary. Methods and Materials: From 1958 to 1991,60 patients with PCS were treated at the Cancer Hospital of Chinese Academy of Medical Sciences, Beijing. They presented with a lower abdominal mass and showed a predominance for the right side. A high proportion of patients with PCS [ 26 of 60 (43% )] had metastatic disease, compared to 20% of those with scrotal seminoma, and there was a tendency toward a higher frequency of pelvic nodal metastases. There were 34 Stage I, 6 Stage IIA, 11 Stage IIB, 5 Stage III, and 4 Stage IV patients. Of these 60 patients, 56 underwent laparotomy with or without cryptorchiectomy (37 radical orchiectomy, 7 partial orchiectomy, and 12 biopsy of the primary or cervical node), and 4 cervical node biopsy only. All patients were further treated with radiotherapy, chemotherapy, or a combination of both. Patients with Stage I and II disease received radiotherapy, whereas patients with Stage III and IV were treated with chemotherapy. Results: The overall and disease-free survivals at 5 and 10 years were 92% and 87%, and 88% and 84%, respectively. The 5- and lo-year survivals were 100% for Stage I, 94% and 87% for Stage II, and 56% and 42% for Stage III/IV, respectively @ < 0.05). Volume of irradiation, i.e., whole abdominal-pelvic radiotherapy ( 10 patients), versus hockey-stick encompassing paraaortic, ipsilateral iliac nodes and the primary tumor or tumor bed (17) did not influence outcome in Stage I patients. Five patients relapsed within 2-12 years after treatment, and four of these patients were successfully salvaged. Four patients developed a second malignant tumor and died. Conclusion: Stage I and II PCS can he adequately controlled by radiotherapy regardless of the surgical procedure. Whole abdominal-pelvic irradiation for Stage I and IIA disease is not required, and fields can be limited to the paraaortic, ipsilateral iliac nodes and primary tumor or tumor bed. We recommend platinum-based chemotherapy for Stage IIB-IV PCS. 0 1997 Elsevier Science Inc. [less ▲]

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See detailLe Système d'informations sur la Biodiversité en Wallonie.
Dufrêne, Marc ULg

in Les cahiers des Réserves Naturelles RNOB (1997), 11

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See detailThe yeast genome directory.
Goffeau, A.; Hilger, F.; Portetelle, Daniel ULg et al

in Nature (1997), 387(5),

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See detailUse of anti inflammatory drugs in the treatment of bovine respiratory disease complex
Lekeux, Pierre ULg; VandeWeerdt, M. L.

in Israel Journal of Veterinary Medicine (1997), 52(2-3), 113-116

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See detailLes strychnos africains et leurs alcaloïdes
Delaude, Clément ULg; Delaude, Lionel ULg

in Bulletin de la Société Royale des Sciences de Liège (1997), 66(4), 183-286

In the Greek Antiquity, the term strychnos was first coined to describe various toxic Solanacae. Nowadays, the genus Strychnos created by Linnaeus in 1753 is the numerically most important genus from the ... [more ▼]

In the Greek Antiquity, the term strychnos was first coined to describe various toxic Solanacae. Nowadays, the genus Strychnos created by Linnaeus in 1753 is the numerically most important genus from the Loganiaceae family and comprises 196 species growing in the warm regions of Asia (58 species), America (64) and Africa (75). Species on the three continents are almost totally segregated. Only Strychnos potatorum is common to Asia and Africa. The toxicity of Strychnos was empirically well-known from time immemorial. Inhabitants of South-Eastern Asia and India had an ancestral knowledge of Strychnos nux vomica, whose deadly poisonous seeds were later imported and marketed in Europe to kill rodents and small predators. Concentrated extracts from Amazonian Strychnos, known as curares, are also remarkable hunting poisons, used by South American Indians. Accordingly, modern scientific investigations of Strychnos and their alkaloids started with Asian or American species used as traditionnal poisons. Strychnine was the first alkaloid found in Strychnos. It was isolated from Asian S. nux vomica in 1818, but its structure was fully elucidated only in the 1950s. Meanwhile, various curarizing alkaloids from American Strychnos were identified. Based on these early results, Strychnos alkaloids were initially classified according to their geographical origin. Asian Strychnos were assumed to contain strychnine and related compounds, whereas curarizing ammonium salts were associated with American Strychnos. African species were assimilated to their Asian counterparts and deemed of less interest. During the last three decades, however, systematic screening of African Strychnos has revealed the presence of numerous, varied alkaloids in these plants and demonstrated that the correlation between geographical distribution and alkaloid content was erroneous. Presently, 47 African species have been investigated and their alkaloids analyzed, significantly more than Asian and American materials (about 10 and 20 species, respectively). In this review, we present the alkaloids isolated so far from African Strychnos. 309 structures are listed and sorted according to their molecular weight, the most useful index key in modern research based on mass spectrometry. [less ▲]

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See detailSarcoidosis: recognition and treatment guidelines
Kaye, O.; Ribbens, Clio ULg; Kahn, M. F. et al

in BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals & Gene Therapy (1997), 7(6), 441-447

Sarcoidosis is a systemic disorder of unknown aetiology characterised by noncaseating granulomas leading principally to bilateral hilar lymphadenopathies, pulmonary infiltration and skin and eye lesions ... [more ▼]

Sarcoidosis is a systemic disorder of unknown aetiology characterised by noncaseating granulomas leading principally to bilateral hilar lymphadenopathies, pulmonary infiltration and skin and eye lesions. Sarcoidosis may involve other organs, including peripheral lymph nodes, liver, spleen, nervous and musculoskeletal systems, heart, ear, nose and kidney. Although the clinical involvement of liver and heart is relatively uncommon, hepatic and cardiac granulomas are present at autopsy in about 70 to 80% and 25 to 50%, respectively, of patients with this disease. The diagnosis of sarcoidosis includes compatible clinical and/or radiological presentations and histological evidence of noninfectious and noncaseating epitheloid cell granulomas in the absence of other identifiable agents responsible for such histological lesions. Disease course is variable and usually characterised by frequent remissions, but it may become progressive and chronic in a small percentage of patients. The optimal treatment of sarcoidosis remains poorly defined. In patients with progressive pulmonary dysfunction as well as in those with severe extrapulmonary localisations, systemic corticosteroids usually represent the first approach, limited by long term toxicity and frequent relapses after treatment interruption. In the presence of refractory or corticosteroid-dependent forms of the disease, antimalarial drugs or low dosage methotrexate may be used with prolonged benefit. The indications for immunosuppressive agents such as azathioprine, chlorambucil, cyclophosphamide and cyclosporin are uncommon and limited because of potentially serious adverse effects and lack of information on their long term efficacy. In the case of ocular and limited cutaneous manifestations, local corticosteroid therapy may be useful. [less ▲]

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See detailOrigine sociale et réussite scolaire : un modèle en Chaîne de Markov estimé sur données individuelles belges
Donni, Olivier; Lejeune, Bernard ULg

in Recherches Economiques de Louvain (1997), 63(4), 421-446

Cet article étudie les relations entre l'origine socio-économique des élèves belges et leur parcours scolaire primaire et secondaire. Il repose sur l'hypothèse que le parcours scolaire des élèves peut ... [more ▼]

Cet article étudie les relations entre l'origine socio-économique des élèves belges et leur parcours scolaire primaire et secondaire. Il repose sur l'hypothèse que le parcours scolaire des élèves peut être décrit par un processus de Markov. Sur la base d'un échantillon transversal d'un millier d'enfants, en fonction de variables socio-économiques et pour chacune des années de scolarité obligatoire, les probabilités individuelles de poursuivre un parcours scolaire ''normal'', c.-à-d. sans redoublement ni relégation dans une filière de second choix, sont estimées. Nos résultats montrent que derrière les substantiels taux agrégés de redoublement qui caractérisent le système scolaire belge se cachent en fait de profondes inégalités sociales. [less ▲]

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See detailBiomarqueurs et bioindicateurs chez les vertébrés : importance pour l’évaluation de la santé d’un écosystème
Lessire, Françoise ULg; Delaunois, Annie; Gustin, Pascal ULg et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailAu fil du fleuve. Entretien avec Luc et Jean-Pierre Dardenne
Mélon, Marc-Emmanuel ULg; d'Autreppe, Emmanuel; Flamant, Nathalie et al

in Revue belge du cinéma (1997), 41

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See detailTrajectoire déviante à la lisière entre adolescence et âge adulte
Gavray, Claire ULg

in Déviance et Société (1997), 21(3), 273-288

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See detailEvaluation of pleural diseases with FDG-PET imaging: preliminary report.
Bury, Thierry ULg; Paulus, P; Dowlati, A et al

in Thorax (1997), 52(2), 187-9

BACKGROUND: Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis ... [more ▼]

BACKGROUND: Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis of pleural disease was investigated in 25 patients. METHODS: PET was performed on each subject before invasive procedures were used to determine the aetiological diagnosis. The PET data were analysed by visual interpretation of coronal, sagittal, and transverse slices. RESULTS: Sixteen patients were found to have malignant pleural disease and nine had benign disease. All patients with histologically confirmed malignant disease showed FDG uptake within the pleural thickening which was intense in 14 cases and moderate in two. PET imaging showed the absence of FDG uptake and correctly categorised seven non-malignant lesions. Two patients with infectious pleural diseases showed a localised and moderate FDG uptake. CONCLUSION: Our preliminary results suggest that FDG-PET could be an effective tool for differentiating between benign and malignant pleural diseases. [less ▲]

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See detailEvidence for a Non-Gabaergic Action of Quaternary Salts of Bicuculline on Dopaminergic Neurones
Seutin, Vincent ULg; Scuvée-Moreau, Jacqueline ULg; Dresse, Albert ULg

in Neuropharmacology (1997), 36(11-12, Nov-Dec), 1653-7

Intracellular recordings were made from neurones, presumed to be dopaminergic, in the rat midbrain slice preparation. Bicuculline methiodide (BMI) and methochloride (BMC) reversibly blocked the slow ... [more ▼]

Intracellular recordings were made from neurones, presumed to be dopaminergic, in the rat midbrain slice preparation. Bicuculline methiodide (BMI) and methochloride (BMC) reversibly blocked the slow, apamin-sensitive component of the afterhyperpolarization in these cells. The IC50 for this effect was about 26 microM. In comparison, BMC antagonized the input resistance decrease evoked by muscimol (3 microM) with an IC50 of 7 microM. The base of bicuculline was less potent in blocking the slow afterhyperpolarization. SR95531 (2-[carboxy-3'-propyl]-3-amino-6-paramethoxy-phenyl-pyridaziniu m bromide), another competitive GABA(A) antagonist, and picrotoxin, a non-competitive GABA(A) antagonist, also blocked the action of muscimol (IC50s: 2 and 12 microM respectively), but had no effect on the afterhyperpolarization at a concentration of up to 100 microM. Moreover, 100 microM SR95531 did not affect the blockade of the afterhyperpolarization by BMC. This blockade persisted in the presence of tetrodotoxin and was apparently not due to a reduction of calcium entry, suggesting that it involved a direct action on the channels which mediate this afterhyperpolarization. These results strongly suggest that quaternary salts of bicuculline act on more than one target in the central nervous system. Thus, the involvement of GABA(A) receptors in a given effect cannot be proven solely on the basis of its blockade by these agents. [less ▲]

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See detailAutour de Benjamin et Arendt
Delruelle, Edouard ULg

in Revue belge de Cinéma (1997), 41

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See detailProduction and activation of matrix metalloprotease-9 (MMP-9) by HL-60 promyelocytic leukemia cells
Devy, L.; Noël, Agnès ULg; Baramova, E. et al

in Biochemical and Biophysical Research Communications (1997), 238

Human promyelocytic HL-60 cells have been used as a model of acute leukemia to investigate the expression and the regulation of matrix metalloproteases (MMPs), known to contribute to the degradation of ... [more ▼]

Human promyelocytic HL-60 cells have been used as a model of acute leukemia to investigate the expression and the regulation of matrix metalloproteases (MMPs), known to contribute to the degradation of extracellular matrix components. As shown by gelatin zymography, HL-60 cells constitutively released significant amounts of proMMP-9 (92 kDa) and moderate amounts of proMMP-2 (72 kDa). Furthermore, casein zymography confirmed the presence of serine proteases in the form of pro-urokinase. Activation of proMMP-9 was dependent on the plasminogen activator/plasmin (PA/plasmin) system and was inhibited by aprotinin. MMP-9 was only detected in cellular extracts or conditioned media incubated with HL-60 cells, indicating that cells are essential to the activation process. Addition of plasminogen increased by 3-fold the basal invasive rate of these cells across a matrigel layer (2.1%versus0.7% in control cells after 4 h of incubation). Taken together, these results indicate that HL-60 cells exhibit an autocrine activation mechanism of proMMP-9 via the PA/plasmin system and that activation of proMMP-9 increases their invasive potential [less ▲]

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See detailLattice dynamics and ferroelectric instability of barium titanate
Ghosez, Philippe ULg; Gonze, X.; Michenaud, J. P.

in Ferroelectrics (1997), 194

Using first-principles calculations, we investigate the lattice dynamics of cubic and rhombohedral BaTiO3 and rye discuss the origin of the structural instability of this ferroelectric material. First, we ... [more ▼]

Using first-principles calculations, we investigate the lattice dynamics of cubic and rhombohedral BaTiO3 and rye discuss the origin of the structural instability of this ferroelectric material. First, we report results on the Born effective charges and the dielectric tensor and we emphasize the important reduction of these quantities in the ferroelectric phase, Then, the phonon frequencies at the Gamma point are calculated. We point out the similarity of theoretical eigenvectors in the cubic and rhombohedral phases. We examine the interaction of the vibration modes with the electric field and in particular the giant LO-TO splitting of the ferroelectric mode. Finally, separating the dipole-dipole interaction from the remaining short-range forces, we quantify the balance of forces leading to an unstable phonon in the cubic phase and we demonstrate its sensitivity to tiny effective charge changes. Within our decomposition, the stabilization of the unstable mode in the rhombohedral phase is produced by a reduction of the Born effective charges, while its stabilization under isotropic pressure is associated with a modification of the short-range forces. [less ▲]

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See detailThe Nucleotide Sequence Of Saccharomyces Cerevisiae Chromosome XII
Johnston, M.; Hillier, L.; Riles, L. et al

in Nature (1997), 387(6632),

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See detailTwo Members Of The Human Mageb Gene Family Located In Xp21.3 Are Expressed In Tumors Of Various Histological Origins
Lurquin, C.; De Smet, C.; Brasseur, F. et al

in Genomics (1997), 46(3), 397-408

Genes of the MAGE family direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. Twelve closely related MAGE genes are located in the Xq28 region ... [more ▼]

Genes of the MAGE family direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. Twelve closely related MAGE genes are located in the Xq28 region. These genes share 60-98% nucleotide identity in their coding region. The presence of homologous genes in a region of Xp21.3 has been reported previously. We obtained the complete sequence of a 42-kb stretch of this region. It contains four MAGE-related genes, which we propose to name MAGE-B1, B2, B3, and B4 (HGMW-approved symbols MAGEB1, MAGEB2, MAGEB3, and MAGEB4). The coding regions of these genes share 66-81% nucleotide identity and show 45-63% identity with those of the MAGE genes located in Xq28. Like the MAGE genes located in Xq28, the MAGE-B genes are silent in normal tissues with the exception of testis. Like MAGE-1, 2, 3, 4, 6 and 12 (HGMW-approved symbols MAGEA1, 2, 3, 4, 6, and 12), genes MAGE-B1 and MAGE-B2 are expressed in a significant fraction of tumors of various histological types. The transcription of MAGE-B1 and MAGE-B2 can be induced by 5-aza-2'-deoxycytidine, suggesting that the activation of these genes in tumors results from a demethylation process. [less ▲]

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See detailRecherche d'information et pragmatisme : I. Le paradigme de la confirmation d'hypothèses
Dardenne, Benoît ULg; Leyens, J.; Yzerbyt, V. Y.

in Année Psychologique (L') (1997), 97

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See detailIdentification des vaches laitières traitées à la somatotropine bovine
Scippo, Marie-Louise ULg; Degand, Guy ULg; Duyckaerts, Anne et al

in Annales de Médecine Vétérinaire (1997), 141(5), 381-390

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See detailA 12 Kb Nucleotide Sequence Containing The Alanine Dehydrogenase Gene At 279 Degrees On The Bacillus Subtilis Chromosome
Oudega, B.; Vandenbol, Micheline ULg; Koningstein, G.

in Microbiology-Uk (1997), 143

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See detailRelationships among estimates of inbreeding depression, dominance and additive variance for linear traits in Holsteins
Misztal, I.; Lawlor, T. J.; Gengler, Nicolas ULg

in Genetics, Selection, Evolution (1997), 29(4), 319-326

Estimates of dominance and additive variances were obtained for 14 linear traits. The data included 600 678 first parity records on 14 linear traits in Holsteins. The model included management groups, age ... [more ▼]

Estimates of dominance and additive variances were obtained for 14 linear traits. The data included 600 678 first parity records on 14 linear traits in Holsteins. The model included management groups, age at calving, additive and dominance effects, and regression on inbreeding percentage. The estimate of the dominance variance was 9.8% of the phenotypic variance for body depth: 8.0% for strength, 6.9% for stature, and was less than 5% for the remaining traits. The additive variance ranged from 12.2% for foot angle to 45.3% for stature. No clear relationship was found between the estimates of dominance and additive variance. larger negative estimates of the inbreeding depression were associated with higher estimates of the dominance variance. [less ▲]

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See detailLes moyens de se prémunir contre la défaillance de ses cocontractants
Georges, Frédéric ULg

in Actualités du Droit (1997)

Cette contribution commentait l'impact de la réforme de 1997 du droit de l'insolvabilité sur les droits des créanciers

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See detailSchool Geography Textbooks in Francophone Belgium
Merenne-Schoumaker, Bernadette ULg

in International Research in Geographical & Environmental Education (1997), 6(1), 86-88

Review on the situation of geographical textbooks in Belgium since the French education reform in 1969

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See detailLes armées d'Alexandre le Grand et les langues étrangères
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1997), 66

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See detailLes pesticides: effets endocriniens et cancérogènes chez l'Homme
Charlier, Corinne ULg; Plomteux, Guy ULg

in Toxicorama (1997), IX

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