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See detailConformal invariance and degrees of freedom in the QCD string
Dienes, Keith R; Cudell, Jean-René ULg

in Physical Review Letters (1994), 72

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See detailHooliganisme et extrémisme
Comeron, Manuel ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1994), 1

Les dimensions de racisme et d'extrémisme politique sont liés aux problèmes de sécurité et de violence posés par les supporters de football.

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See detailThe functional proof of the diaphragm's specific type of motor innervation in Ongulae
Desmecht, Daniel ULg; Linden, Annick ULg; Leroy, Pascal ULg et al

in Pflügers Archiv : European Journal of Physiology (1994), 426

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See detailMéléagre dans les Argonautiques
Renaud, Jean-Michel ULg

in Uranie : Mythes et Littératures (1994), 4

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See detailRôle de la chirurgie carotidienne dans la prévention de l'infarctus cérébral
Limet, Raymond ULg; DESIRON, Quentin ULg; DETRY, Olivier et al

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1994), 149(5-7), 299-305306-7

A significant part of transient or permanent cerebral ischemic attacks (CIA) are due to arterio-arterial emboli issued from carotid plaques. Surgery for carotid disobstruction aims to take out emboligenic ... [more ▼]

A significant part of transient or permanent cerebral ischemic attacks (CIA) are due to arterio-arterial emboli issued from carotid plaques. Surgery for carotid disobstruction aims to take out emboligenic plaques by endarterectomy (associated to angioplasty or not). The adversaries of surgical treatment sustain two main assertions: 1. carotid stenoses are not very dangerous, because the definitive thromboses they create are easily compensated by the development of collaterals, so that the risk for stroke is low. 2. this low and late risk of spontaneous carotid thrombosis is not greater than the immediate one following carotid surgery. Those objections have been encountered in randomized North American studies (Nascet [less ▲]

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See detailCARAIB - A global model of terrestrial biological productivity
Warnant, Pierre ULg; François, Louis ULg; Strivay, David ULg et al

in Global Biogeochemical Cycles (1994), 8(3), 255-270

CARAIB, a mechanistic model of carbon assimilation in the biosphere estimates the net primary productivity (NPP) of the continental vegetation on a grid of 1 degrees x 1 degrees in latitude and longitude ... [more ▼]

CARAIB, a mechanistic model of carbon assimilation in the biosphere estimates the net primary productivity (NPP) of the continental vegetation on a grid of 1 degrees x 1 degrees in latitude and longitude. The model considers the annual and diurnal cycles. It is based on the coupling of the three following submodels; a leaf assimilation model including estimates of stomatal conductance and leaf respiration, a canopy model describing principally the radiative transfer through the foliage, and a wood respiration model. Present-day climate and vegetation characteristics allow the discrimination between ecotypes. In particular, specific information on vegetation distribution and properties is successfully used at four levels; the leaf physiological level, the plant level, the ecosystem level, and the global level. The productivity determined by the CARAIB model is compared with local measurements and empirical estimates showing a good agreement with a global value of 65 Gt C yr(-1). The sensitivity of the model to the diurnal cycle and to the abundance of C-4 species is also tested. The productivity slightly decreases (10%) when the diurnal cycle of the temperature is neglected. By contrast, neglecting the diurnal cycle of solar irradiance produces unrealistically high values of NPP. Even if the importance of this increase would presumably be reduced by the coupling of CARAIB with a nutrient cycle model, this test emphasizes the key role of the diurnal cycle in a mechanistic model of the NPP. Uncertainties on the abundance and spatial distribution of C-4 plants may cause errors in the NPP estimates, however, as demonstrated by two sensitivity tests, these errors are certainly lower than 10% at the global scale as shown by two tests. [less ▲]

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See detailThe Pepinster formation in the Verviers synclinorium, between Pepinster and Eupen (Belgium). Structural and stratigraphical context
Hance, Luc ULg; Dejonghe, L; Fairon-Demaret, Muriel ULg et al

in Annales de la Société Géologique de Belgique (1994), 117

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See detailChromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers
Cockett, N. E.; Jackson, S. P.; Shay, T. D. et al

in Proceedings of the National Academy of Sciences of the United States of America (1994), 91

A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic sheep (Ovis aries). Preliminary results indicate that an autosomal ... [more ▼]

A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic sheep (Ovis aries). Preliminary results indicate that an autosomal dominant gene may be responsible for this economically advantageous trait. We have exploited the conservation in sequence and chromosomal location of DNA markers across Bovidae to map the corresponding callipyge locus to ovine chromosome 18 using a battery of bovine chromosome 21 markers. Chromosomal localization of the ovine callipyge locus is the first step toward positional cloning of the corresponding gene. [less ▲]

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See detailActualités bibliographiques: les assurances dans la littérature criminologique
Lemaître, André ULg

in Déviance et Société (1994), 18(N°3), 297-329

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See detailNuclear magnetic resonance spectroscopy : insights into experimental septic shock
GILLES, R; CARLIER, PG; D'Orio, Vincenzo ULg

in Intensive Care Medicine (1994)

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See detailFear reactions of ewes to photographic images
Vandenheede, Marc ULg; Bouissou, Marie-France

in Behavioural Processes (1994), 32

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See detailDe l'école à l'entreprise ou le processus d esocialisation mis en échec
Robert, Jocelyne ULg

in Eucation-Formation (1994)

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See detailThe phytoplankton community of the river Meuse, Belgium: seasonal dynamics (year 1992) and the possible incidence of zooplankton grazing
Gosselain, Véronique ULg; Descy, Jean-Pierre; Everbecq, Etienne ULg

in Hydrobiologia (1994), 289

Qualitative and quantitative aspects of the phytoplankton of the river Meuse were studied during 1992 at a point 537 km from the source. The phytoplankton was dominated by diatoms and green algae. The ... [more ▼]

Qualitative and quantitative aspects of the phytoplankton of the river Meuse were studied during 1992 at a point 537 km from the source. The phytoplankton was dominated by diatoms and green algae. The factors regulating the phytoplankton groxth were clearly physical variables : discharge, temperature and irradiance. [less ▲]

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See detailMutation analysis of coding sequences for type I procollagen in individuals with low bone density.
Spotila, L. D.; Colige, Alain ULg; Sereda, L. et al

in Journal of Bone and Mineral Research (1994), 9(6), 923-32

Mutations in one of the two genes encoding type I procollagen (COL1A1 and COL1A2) are frequently the cause of osteogenesis imperfecta (OI), a disorder characterized by brittle bones. Here we tested ... [more ▼]

Mutations in one of the two genes encoding type I procollagen (COL1A1 and COL1A2) are frequently the cause of osteogenesis imperfecta (OI), a disorder characterized by brittle bones. Here we tested whether patients with low bone density also have mutations in these genes. The 26 patients studied had no apparent metabolic bone disease, but most had a positive family history of osteopenia or osteoporosis. Although a diagnosis of OI was considered by the clinician in some cases, the clinical criteria for OI were not satisfied. Our strategy for mutation analysis consisted of PCR amplification of cDNA made to fibroblast mRNA using primers specific for the coding regions of COL1A1 and COL1A2. The PCR products were then sequenced directly with primers located within each PCR product. We found that 3 of 26 patients had mutations that altered the encoded amino acid. One mutation, at position alpha 2(I)-661 has been reported (Spotila et al. 1991 Proc Natl Acad Sci USA PNAS 88:5423). The other 2 patients, who were not related to each other, had a mutation that altered the proline codon at alpha 1(I)-27 to alanine. This mutation was not found in 81 normal individuals or in 37 additional osteopenic individuals. However, its effect on the biologic function of type I collagen, as well as its role in osteopenia, is uncertain. In addition to the two mutations, we found a polymorphism in codon alpha 2(I)-459. Although this polymorphism involved an amino acid substitution, it was present with equal frequency in the patient and the normal population. By analyzing this and previously reported neutral sequence variants in the COL1A2 gene, we determined that all patients expressed both alleles of the COL1A2 gene. The 12 patients who were heterozygous for a COL1A1 neutral sequence variant also expressed both alleles. Here we present all PCR primer and sequencing primer information. The results suggest that surveying a larger group of similarly selected individuals may reveal additional mutations in the COL1A1 or COL1A2 genes. [less ▲]

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See detailPilgrimage out of Dispossession
Pagnoulle, Christine ULg

in Commonwealth : Essays and Studies (1994), 17(1), 100-106

Goodison's poems testify to her proud self-assertion, both as woman and as a descendant of African slaves.

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See detailHereditary muscular hypertrophy in cattle is associated with a reduced myocardial contractility
Amory, Hélène ULg; Mc Entee, Kathleen ULg; Linden, Annick ULg et al

in Pflügers Archiv : European Journal of Physiology (1994), 426

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See detailMonofrequency Forced Oscillation Technique for the Investigation of Pulmonary Function in Calves: In Vitro and in Vivo Studies
Close, Roland; Reinhold, Petra; Lekeux, Pierre ULg

in Research in Veterinary Science (1994), 56(3), 363-372

Parameters derived from the non-invasive and simple monofrequency forced oscillation technique were compared with classical parameters of ventilatory mechanics in order to assess its usefulness for the ... [more ▼]

Parameters derived from the non-invasive and simple monofrequency forced oscillation technique were compared with classical parameters of ventilatory mechanics in order to assess its usefulness for the investigation of pulmonary function in calves. To facilitate this comparison, theoretical derivations were coupled with in vitro measurements, using an artificial lung model, and with in vivo studies. These studies compared the oscillatory resistance parameters (Ros and Re) and the respiratory system compliance (Crs) against the classical pulmonary resistance (RL) and the dynamic compliance (Cdyn), respectively. Ros and Re were highly correlated (r > or = 0.87) with RL and the comparison between Crs and Cdyn gave a similarly high correlation (r > or = 0.88). Given its simplicity, its correspondence with classical parameters and its rapidity and reproducibility, monofrequency forced oscillation technique seems well suited for the investigation of pulmonary function under field conditions. [less ▲]

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See detailDe limite en frontière : le monde à la mesure de l'homme
Bachelet, Jean-François ULg

in Revue de l'Institut de Sociologie (1994), 3-4

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See detailIGF-I and IGFBP-3 increase independently of testosterone release during the onset of puberty in cattle
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

in Growth Regulation (1994), 4(suppl 1), 116

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See detailQuelle stratégie pour le développement rural dans la structuration de l'espace régional?
Rondeux, Jacques ULg

in Annales de Gembloux (1994), 100(3-4), 93-107

L’espace rural comporte tellement de paramètres et de diversités et vit aujourd’hui tellement de mutations que le définir de manière précise est une gageure. On pourrait dire qu’il concerne un territoire ... [more ▼]

L’espace rural comporte tellement de paramètres et de diversités et vit aujourd’hui tellement de mutations que le définir de manière précise est une gageure. On pourrait dire qu’il concerne un territoire essentiellement agricole, à contours diffus, caractérisé par une grande diversité où l’homme y voit une source d’activités multiples, saisonnières ou complémentaires, de services gratuits et de ressources renouvelables : l’air, l’eau, le paysage. Ce n’est pas la ville, ce n’est pas le site industriel mais cela peut être les champs entre deux agglomérations, la forêt entre deux villes et surtout les grands espaces, le monde ouvert dans lequel on oublierait un peu vite que pour maintenir son originalité et valoriser ses atouts et donc se développer il doit se raccrocher à des villes, chacun tirant profit des spécificités et des potentialités de l’autre. Non au désert économique, non aux services systématiquement gratuits, non à l’absence de tissu urbain adapté ; voilà les conditions pour le maintien ou pour un oui à une agriculture revue et corrigée, à la qualité de la vie, à la beauté des paysages, aux espaces de liberté et de détente, en un mot à une nouvelle ruralité basée sur la solidarité. [less ▲]

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See detailLa prothèse pénienne dans le traitement de l'impuissance: La décision du patient
Kempeneers, Philippe ULg; Andrianne, R.; Mormont, Christian ULg

in Cahiers de Sexologie Clinique (1994), 20(124), 31-36

In the population who look advice from our interdisciplinary team, penile prosthesis is estimated been indicated in about 13% of the cases. Among these 13% of patients to whom a penile implant was ... [more ▼]

In the population who look advice from our interdisciplinary team, penile prosthesis is estimated been indicated in about 13% of the cases. Among these 13% of patients to whom a penile implant was proposed, only 32% agreed to undergo the operation. From this statement, we wondered why some men require penile implantation and other ones resign. A follow-up survey allowed to compare the experience of 19 implants recipients to the experience of 17 patients who have refused this solution. The cost of the device appears being a very determinant argument in the decision to reject penile implantation. Our study fails to distinguls clearly the two groups of subjects on the basis of another motivation criterion. [less ▲]

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See detailPyoverdine production is not the sole trait involved in the biological control of soil diseases by Pseudomonas fluorescens ATCC 17400.
Jacques, Philippe ULg; Cornelis, P.; Gaballa, A. et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1994), 102(B81),

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See detailEtude multicentrique du dosage de la transferrine déficiente en acide sialique par deux techniques chromatographiques
Vernet, M.; Renversez, J. C.; Revenant, M. C. et al

in Annales de Biologie Clinique (1994), 52

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See detailFluid transfer in anorthosites and related rocks from Rogaland (Southwest Norway): Evidence from stable isotopes
Wilmart, Edith; Pineau, Françoise; Réjou-Michel, A. et al

in Earth & Planetary Science Letters (1994), 125

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See detailLymphocyte Lifespan in Murine Retrovirus-Induced Immunodeficiency
Moutschen, Michel ULg; Colombi, S.; Deprez, Manuel ULg et al

in Advances in Experimental Medicine and Biology (1994), 355

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See detailCinétique de récupération fonctionnelle de la ventilation pulmonaire après pontage aortocoronaire
Croisier, Jean-Louis ULg; Parisse, J.; Camus, G. et al

in Annales de Réadaptation et de Médecine Physique (1994), 37

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See detailDimensionless critical shear stress evaluation from flume experiments using different gravel beds
Petit, François ULg

in Earth Surface Processes & Landforms (1994)

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See detailENANTIOSELECTIVE SYNTHESES OF NCA (S)-L-[BETA-C-11]-4-CHLOROPHENYLALANINE AND (S)-L-(ALPHA-METHYL)-[BETA-C-11]-4-CHLOROPHENYLALANINE
Plenevaux, Alain ULg; Al-Darwich, M. J.; Lemaire, Christian ULg et al

in Applied Radiation & Isotopes (1994), 45(3), 361-369

The radiolabeling of (S)-L-4-chlorophenylalanine and (S)-L-(alpha-methyl)-4-chlorophenylalanine were realized with carbon-11 at position beta through a radiochemical synthesis relying on the highly ... [more ▼]

The radiolabeling of (S)-L-4-chlorophenylalanine and (S)-L-(alpha-methyl)-4-chlorophenylalanine were realized with carbon-11 at position beta through a radiochemical synthesis relying on the highly enantioselective reaction between 4-chloro[alpha-C-11]benzyl bromide and the lithium enolate of (S)-1-(t-butyloxycarbonyl)-2-(t-butyl)-3-methyl-1,3-imidazolidine-4-one for (S)-L-[beta-C-11]-4-chlorophenylalanine and of (2S,5S)-1-(t-butyloxycarbonyl)-2-(t-butyl)-3,5-dimethyl-1,3-imidazolidin e-4-one for (S)-L-(alpha-methyl)-[beta-C-11]-4-chlorophenylalanine. Quantities of about 25-35 mCi were obtained at the end of synthesis, ready for injection, after hydrolysis and HPLC purification with a radiochemical yield of 19% corrected to EOB within 45 min. The enantiomeric excesses were shown to be greater than or equal to 97% for both molecules without chiral separation. The radiochemical and the chemical purities of the final compounds were greater than or equal to 98% and the specific activity at the end of synthesis ranged between 250-800 mCi/mu mol. [less ▲]

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See detailAvailability of glucose ingested during muscle exercise performed under acipimox-induced lipolysis blockade.
Gautier, J. F.; Pirnay, Freddy ULg; Jandrain, Bernard ULg et al

in European Journal of Applied Physiology and Occupational Physiology (1994), 68(5), 406-12

This study investigated the percentage of carbohydrate utilization than can be accounted for by glucose ingested during exercise performed after the ingestion of the potent lipolysis inhibitor Acipimox ... [more ▼]

This study investigated the percentage of carbohydrate utilization than can be accounted for by glucose ingested during exercise performed after the ingestion of the potent lipolysis inhibitor Acipimox. Six healthy male volunteers exercised for 3 h on a treadmill at about 45% of their maximal oxygen uptake, 75 min after having ingested 250 mg of Acipimox. After 15-min adaptation to exercise, they ingested either glucose dissolved in water, 50 g at time 0 min and 25 g at time 60 and 120 min (glucose, G) or sweetened water (control, C). Naturally labelled [13C]glucose was used to follow the conversion of the ingested glucose to expired-air CO2. Acipimox inhibited lipolysis in a similar manner in both experimental conditions. This was reflected by an almost complete suppression of the exercise-induced increase in plasma free fatty acid and glycerol and by an almost constant rate of lipid oxidation. Total carbohydrate oxidation evaluated by indirect calorimetry, was similar in both experimental conditions [C, 182, (SEM 21); G, 194 (SEM 16) g.3 h-1], as was lipid oxidation [C, 57 (SEM 6); G, 61 (SEM 3) g.3 h-1]. Exogenous glucose oxidation during exercise G, calculated by the changes in 13C:12C ratio of expired air CO2, averaged 66 (SEM 5) g.3 h-1 (19% of the total energy requirement). Consequently, endogenous carbohydrate utilization was significantly smaller after glucose than after placebo ingestion: 128 (SEM 18) versus 182 (SEM 21) g.3 h-1, respectively (P < 0.05). Symptoms of intense fatigue and leg cramps observed with intake of sweet placebo were absent with glucose ingestion.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailEndoscopic management of ectopic pregnancy.
Donnez, Jacques; NISOLLE, Michelle ULg

in Bailliere's Clinical Obstetrics & Gynaecology (1994), 8(4), 707-2

The rationale for the conservative management of ectopic pregnancy is the preservation of reproductive potential. Removal of trophoblast through a linear incision (salpingotomy) can be easily performed by ... [more ▼]

The rationale for the conservative management of ectopic pregnancy is the preservation of reproductive potential. Removal of trophoblast through a linear incision (salpingotomy) can be easily performed by endoscopy. The injection of vasopressin into the broad ligament is required in less than 10% of cases and its routine use is not recommended because of the risk of severe side-effects. The techniques in cases of isthmic or cornual tubal pregnancy are also described. Other alternatives such as expectant management, methotrexate, RU 486 and prostaglandins have also recently been proposed. Although methotrexate therapy has been demonstrated to be effective in cases of unruptured tubal pregnancy, further studies are needed to determine whether or not this medical therapy is a safer option than laparoscopic surgery and to compare the subsequent intrauterine and recurrent ectopic pregnancy rates. Endoscopic salpingotomy is an efficacious procedure. Indeed, residual trophoblast is found in only 5% of cases after this surgical procedure. In these cases of persistent trophoblast, methotrexate is proposed as the medical approach of choice. Evaluation of the postoperative fertility after linear salpingotomy demonstrates an intrauterine pregnancy rate of 63% and a recurrent ectopic pregnancy rate of 8%. In conclusion, endoscopic management of tubal pregnancy is a safe and efficacious therapy. The contraindications are relative and depend essentially on the surgeon's experience. [less ▲]

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See detailRecherches paléolithiques et mésolithiques en Belgique, 1993: le Trou Magrite, Huccorgne et l'Abri du Pape
Noiret, Pierre ULg; Otte, Marcel ULg; Straus, Lawrence et al

in Notae Praehistoricae (1994), 13

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See detailCo-movements and dynamic interrelationships in pacific basin stock markets
Corhay, Albert ULg; Tourani-Rad, Alireza; Urbain, Jean-Pierre ULg

in Research in International Business and Finance (1994), 11B

In this paper, we investigate dynamic interrelationships among the stock markets of Australia, Hong Kong, Japan, New Zealand and Singapore. Using cointegration analysis and the Granger causality test we ... [more ▼]

In this paper, we investigate dynamic interrelationships among the stock markets of Australia, Hong Kong, Japan, New Zealand and Singapore. Using cointegration analysis and the Granger causality test we find that, although the five stock price indices share some common trends, the only stock price which does not apparently Granger cause (precede) the remaining stock prices is that of New Zealand. It is further observed that all price indices are caused by the remaining stock prices except that of Australia. With respect to the geographical separation, it appears that when we consider the Asian countries as an entity and those of the Pacific as another entity, they seem not to influence each other significantly. [less ▲]

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See detailAsthme et bêta2-agonistes de longue durée d'action
Bury, Thierry ULg; Kayambe, JM; Radermecker, Maurice ULg

in Médecine et Hygiène (1994), 52

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See detailAspergillose chez les oiseaux marins échoués sur la côte belge
Jauniaux, Thierry ULg; Coignoul, Freddy ULg

in Annales de Médecine Vétérinaire (1994), 138(4), 277-281

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species ... [more ▼]

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species. Debilitation and stress are favourable for the mycosis installation in captive wild birds (Zoo and rehabilitation centers). During 90-91 and 91-92 winters, 386 birds found dead at the belgian seashore were necropsied and 9 birds were carriers of specific lesions. Complementary investigations were undertaken. Most animals were oiled and had been kept for some time in rehabilitation centers. [less ▲]

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See detailCharacterization of an up-stream promoter directing extrapituitary expression of the human prolactin gene
Berwaer, M.; Martial, Joseph ULg; Davis, J. R.

in Molecular Endocrinology (1994), 8(5), 635-42

The human PRL gene is expressed outside pituitary lactotrophs in decidualized endometrium and lymphoid cells, but here the mRNA contains a 5'-untranslated region from an additional noncoding exon 1a. We ... [more ▼]

The human PRL gene is expressed outside pituitary lactotrophs in decidualized endometrium and lymphoid cells, but here the mRNA contains a 5'-untranslated region from an additional noncoding exon 1a. We have isolated a genomic DNA clone containing human PRL exon 1a with 2800 basepairs (bp) of 5'-flanking sequences. Sequencing locates exon 1a -5840 bp up-stream of the pituitary start site. To study its suspected regulatory function, various lengths of the 5'-flanking region were linked to the luciferase (Luc) reporter gene. Their ability to direct gene expression has been analyzed in transfection studies. The proximal 1620 bp of promoter sequence directed Luc expression in the T-lymphoid Jurkat cell line, and this was unaffected by 5'-deletion to the proximal 453 bp. However, further 5'-deletion to the most proximal 67 bp drastically reduced this activity by 90%. The exon 1a promoter was inactive in pituitary GH3 cells and HeLa cells; in contrast, the exon 1b pituitary promoter, active in GH3 cells, was inactive in Jurkat cells. DNase-I footprinting studies and further 5'- and 3'-deletion analysis identified factor-binding sites within an enhancer element located at -375/-212 bp, which contributed approximately 50% of the promoter activity. [less ▲]

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See detailDe réels progrès ont-ils été faits dans le traitement de l'ostéoporose ?
Reginster, Jean-Yves ULg; DEROISY, Rita ULg; Franchimont, P

in Les Nouvelles de Rhumatologie (1994), 4

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See detailLigamentoplasties du genou: l'état musculaire préopératoire conditionne t il le degré d'amyotrophie postopératoire?
Croisier, Jean-Louis ULg; Delcour, J. P.; Crielaard, Jean-Michel ULg

in Annales de Réadaptation et de Médecine Physique (1994), 37

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See detailA Partial Approach To Model Checking
Godefroid, Patrice; Wolper, Pierre ULg

in Information & Computation (1994), 110(2), 305--326

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See detailThe Moorcock / Hawkwind Connection: Science Fiction and Rock & Roll Culture
Delville, Michel ULg

in Foundation: The Review of Science Fiction (1994)

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See detailStimulation of glutatione-peroxidase activity decreases HIV type-1 activation after oxidative stress
Sappey, C.; Legrand, Sylvie ULg; Best-Belopmme, M. et al

in AIDS Research and Human Retroviruses (1994), 10(11), 1451-1461

Am important aspect of human immunodeficiency virus (HIV-1) infection is the regulation of its expression by nuclear factor kappa B (NF-kappa B) by redox-controlled signal transduction pathways. In this ... [more ▼]

Am important aspect of human immunodeficiency virus (HIV-1) infection is the regulation of its expression by nuclear factor kappa B (NF-kappa B) by redox-controlled signal transduction pathways. In this study, we demonstrate that selenium supplementation can effectively increase glutathione peroxidase (GPx) activity in latently infected T lymphocytes. The Se-supplemented cells exhibited an important protection against the cytotoxic and reactivating effects of hydrogen peroxide (H2O2). Concomitantly, NF-kappa B activation by H2O2 was also decreased in Se-supplemented cells. Selenium stimulation of GPx activity also induces a protective effect against cell activation by tumor necrosis factor alpha (TNF-alpha) but less significantly by phorbol esters such as PMA. These Se-mediated effects were specific because they were not found when AP-1 DNA-binding activity was studied after H2O2-induced stress. Hyperthermia was also studied because it could promote intracellular electron leakage in electron transport chains. Elevating the temperature to 42 degrees C did not induce NF-kappa B directly. Rather, it sensitized infected cells to subsequent oxidative stress by H2O2, demonstrating the importance of hyperthermia, often associated with opportunistic infections in the development of immunodeficiency. In this case, Se induced partial protection against the sensitizing effect of hyperthermia. [less ▲]

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See detailChloride Permeability of Rat Brain Membrane Vesicles Correlates with Thiamine Triphosphate Content
Bettendorff, Lucien ULg; Hennuy, Benoît ULg; De Clerck, Anne et al

in Brain Research (1994), 652(1), 157-160

Incubation of rat brain homogenates with thiamine or thiamine diphosphate (TDP) leads to a synthesis of thiamine triphosphate (TTP). In membrane vesicles subsequently prepared from the homogenates ... [more ▼]

Incubation of rat brain homogenates with thiamine or thiamine diphosphate (TDP) leads to a synthesis of thiamine triphosphate (TTP). In membrane vesicles subsequently prepared from the homogenates, increased TTP content correlates with increased 36Cl- uptake. A hyperbolic relationship was obtained with a K0.5 of 0.27 nmol TTP/mg protein. In crude mitochondrial fractions from the brains of animals previously treated with thiamine or sulbutiamine, a positive correlation between 36Cl- uptake and TTP content was found. These results, together with other results previously obtained with the patch-clamp technique, suggest that TTP is an activator of chloride channels having a large unit conductance. [less ▲]

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See detailEvolutionary affiliation of the marine nitrogen-fixing cyanobacterium Trichodesmium sp. strain NlBB 1067, derived by 16s ribosomal RNA sequence analysis
Wilmotte, Annick ULg; Neefs, Jean-Marc; De Wachter, Rupert

in Microbiology (1994), 140

The 165 rRNA sequence of Trichodesmium sp. strain NlBB 1067 was determined and used for the construction of a distance tree and bootstrap analysis. The tree shows that, among the available cyanobacterial ... [more ▼]

The 165 rRNA sequence of Trichodesmium sp. strain NlBB 1067 was determined and used for the construction of a distance tree and bootstrap analysis. The tree shows that, among the available cyanobacterial 165 rRNA sequences, Trichodesmium NlBB 1067 has Oscillatoria PCC 7515 as its closest relative, presenting 94.9% of sequence similarity with the latter strain. This is in contrast to a difference of 9 mol O/O G + C in mean genomic DNA base composition between the two organisms. Nevertheless, the genotypic heterogeneity presented by a number of strains assigned to the genus Oscillatoria hinders a taxonomic decision on the separate existence of the genera Trichodesmium and Oscillatoria. The sequence of the internal transcribed spacer (ITS) between the 165 and 23s rRNA genes was also determined, as a possible marker to study inter- and intraspecif ic variability. The ITS contains the genes coding for tRNA1Ie and tRNAAia and its total length is 547 nucleotides. In six out of eight sequenced clones, there is a duplication of 29 nucleotides, surrounding the 5' end of the tRNA1Ie. [less ▲]

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See detailComparative performance study of postal services: a productive efficiency approach
Pestieau, Pierre ULg; Perelman, Sergio ULg

in Annales d'Economie et de Statistique (1994), (33), 187-202

This paper first discusses the notion of economic performance as applied to public enterprises and argues that productive efficiency is an attractive approach to performance measurement for such firms. It ... [more ▼]

This paper first discusses the notion of economic performance as applied to public enterprises and argues that productive efficiency is an attractive approach to performance measurement for such firms. It then presents an empirical efficiency study of postal services which is aimed at comparing productive performance indicators across countries and at testing the effect of competition and regulation on these indicators. [less ▲]

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See detailAnti-LFA-1 (CD11a) monoclonal antibody interferes with the induction of neonatal tolerance to alloantigens
Schurmans, Stéphane ULg; Gonzalez, A.; Revilla, C. et al

in European Journal of Immunology (1994), 24

The injection of (C57BL/6 x BALB/c)F1 spleen cells into newborn BALB/c mice results in the induction of a specific cytotoxic T lymphocyte (CTL) tolerance to the alloantigens. On the contrary, alloreactive ... [more ▼]

The injection of (C57BL/6 x BALB/c)F1 spleen cells into newborn BALB/c mice results in the induction of a specific cytotoxic T lymphocyte (CTL) tolerance to the alloantigens. On the contrary, alloreactive CD4+ T cells persist in the host and are still able to activate autoreactive F1 B cells to produce autoantibodies. This state of "split tolerance" is closely associated with the development of a lupus-like autoimmune syndrome. The LFA-1 integrin plays a relevant role in homing, intercellular adhesion and tranduction of co-stimulatory signals in leukocytes. Because of the beneficial effects of anti-LFA-1 monoclonal antibodies (mAb) treatment in various models of organ transplantation and autoimmune disease, we have investigated if such a treatment could interfere with the induction of neonatal tolerance or the development of the autoimmune syndrome in F1 cell-injected newborn mice. For this purpose, BALB/c mice neonatally injected with F1 cells were treated from day 1 up to day 15 with a non-cytotoxic anti-LFA-1 (CD11a) mAb. Anti-LFA-1 mAb treatment interfered with the persistence of a stable chimerism and with the establishment of CTL tolerance, as shown by rejection of allogeneic skin grafts and F1 B cells, and by a normal in vitro CTL activity against the corresponding alloantigens. As a consequence, these mice did not develop the characteristic autoimmune features seen in close association with an effective induction of CTL tolerance to alloantigens. These results stress the importance of the interactions between LFA-1 and its ligands during the neonatal induction of tolerance to alloantigens [less ▲]

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See detailA common system controls the induction of very different genes. The class-A beta-lactamase of Proteus vulgaris and the enterobacterial class-C beta-lactamase.
Datz, M; Joris, Bernard ULg; Azab, E A et al

in European Journal of Biochemistry (1994), 226(1), 149-57

Among the Enterobacteriaceae, Proteus vulgaris is exceptional in the inducible production of a 29-kDa beta-lactamase (cefuroximase) with an unusually high activity towards the beta-lactamase-stable ... [more ▼]

Among the Enterobacteriaceae, Proteus vulgaris is exceptional in the inducible production of a 29-kDa beta-lactamase (cefuroximase) with an unusually high activity towards the beta-lactamase-stable oximino-cephalosporins (e.g. cefuroxime and cefotaxime). Sequencing of the corresponding gene, cumA, showed that the derived CumA beta-lactamase belonged to the molecular class A. The structural gene was under the direct control of gene cumR, which was transcribed backwards and whose initiation codon was 165 bp away from that of the beta-lactamase gene. This resembled the arrangement of structural and regulator genes ampC and ampR of the 39-kDa molecular-class-C beta-lactamase AmpC present in many enterobacteria. Moreover, cloned genes ampD and ampG for negative modulation and signal transduction of AmpC beta-lactamase induction, respectively, were also able to restore constitutively CumA overproducing and non-inducible P. vulgaris mutants to the inducible, wild-type phenotype. The results indicate that controls of the induction phenomena are equivalent for the CumA and AmpC beta-lactamase. Very different structural genes can thus be under the control of identical systems. [less ▲]

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See detailSECULAR EVOLUTION OF THE VERTICAL COLUMN ABUNDANCES OF CHCLF2 (HCFC-22) IN THE EARTH'S ATMOSPHERE INFERRED FROM GROUND-BASED IR SOLAR OBSERVATIONS AT THE JUNGFRAUJOCH AND AT KITT-PEAK, AND COMPARISON WITH MODEL-CALCULATIONS
Zander, Rodolphe ULg; Mahieu, Emmanuel ULg; Demoulin, Philippe ULg et al

in Journal of Atmospheric Chemistry (1994), 18(2), 129-148

Series of high-resolution infrared solar spectra recorded at the International Scientific Station of the Jungfraujoch, Switzerland, between 06/1986 and 11/1992, and at Kitt Peak National Observatory ... [more ▼]

Series of high-resolution infrared solar spectra recorded at the International Scientific Station of the Jungfraujoch, Switzerland, between 06/1986 and 11/1992, and at Kitt Peak National Observatory, Tucson, Arizona (U.S.A.), from 12/1980 to 04/1992, have been analyzed to provide a comprehensive ensemble of vertical column abundances of CHClF2 (HCFC-22; Freon-22) above the European and the North American continents. The columns were derived from nonlinear least-squares curve fittings between synthetic spectra and the observations containing the unresolved 2nu6 Q-branch absorption of CHClF2 at 829.05 cm-1. The changes versus time observed in these columns were modeled assuming both an exponential and a linear increase with time. The exponential rates of increase at one-sigma uncertainties were found equal to (7.0 +/- 0.35)%/yr for the Junfraujoch data and (7.0 +/- 0.23)%/yr for the Kitt Peak data. The exponential trend of 7.0%/yr found at both stations widely separated in location can be considered as representative of the global increase of the CHClF2 burden in the Earth's atmosphere during the period 1980 to 1992. When assuming two realistic vertical volume mixing ratio profiles for CHClF2 in the troposphere, one quasi constant and the other decreasing by about 13% from the ground to the tropopause, the concentrations for mid-1990 were found to lie between 97 and 111 pptv (parts per trillion by volume) at the 3.58 km altitude of the Jungfraujoch and between .97 and 103 pptv at Kitt Peak, 2.09 km above sea level. Corresponding values derived from calculations using a high vertical resolution-2D model and recently compiled HCFC-22 releases to the atmosphere, were equal to 107 and 105 pptv, respectively, in excellent agreement with the measurements. The model calculated lifetime of CHClF2 was found equal to 15.6 years. The present results are compared critically with similar data found in the literature. On average, the concentrations found here are lower by 15-20% than those derived from in situ investigations; this difference cannot be explained by the absolute uncertainty of +/- 11% assigned presently to the infrared remote measurements. [less ▲]

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See detailMaigret dans ses rapports avec les classes privilégiées
Mouton, Charles ULg

in Revue Générale (1994), 5

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See detailSubcellular Localization and Compartmentation of Thiamine Derivatives in Rat Brain
Bettendorff, Lucien ULg; Wins, Pierre; Lesourd, Monique

in Biochimica et Biophysica Acta (1994), 1222(1), 1-6

The subcellular distribution of thiamine derivatives in rat brain was studied. Thiamine diphosphate content was highest in the mitochondrial and synaptosomal fractions, and lowest in microsomal, myelin ... [more ▼]

The subcellular distribution of thiamine derivatives in rat brain was studied. Thiamine diphosphate content was highest in the mitochondrial and synaptosomal fractions, and lowest in microsomal, myelin and cytosolic fractions. Only 3-5% of total thiamine diphosphate was bound to transketolase, a cytosolic enzyme. Thiamine triphosphate was barely detectable in the microsomal and cytosolic fraction, but synaptosomes were slightly enriched in this compound compared to the crude homogenate. Both myelin and mitochondrial fractions contained significant amounts of thiamine triphosphate. In order to estimate the relative turnover rates of these compounds, the animals received an intraperitoneal injection of either [14C]thiamine or [14C]sulbutiamine (isobutyrylthiamine disulfide) 1 h before decapitation. The specific radioactivities of thiamine compounds found in the brain decreased in the order: thiamine > thiamine triphosphate > thiamine monophosphate > thiamine diphosphate. Incorporation of radioactivity into thiamine triphosphate was more marked with [14C]sulbutiamine than with [14C]thiamine. The highest specific radioactivity of thiamine diphosphate was found in the cytosolic fraction of the brain, though this pool represents less than 10% of total thiamine diphosphate. Cytosolic thiamine diphosphate had a twice higher specific radioactivity when [14C]sulbutiamine was used as precursor compared with thiamine though no significant differences were found in the other cellular compartments. Our results suggest the existence of two thiamine diphosphate pools: the bound cofactor pool is essentially mitochondrial and has a low turnover; a much smaller cytosolic pool (6-7% of total TDP) of high turnover is the likely precursor of thiamine triphosphate. [less ▲]

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See detailUn formalisme unique peut-il décrire les phénomènes acoustiques et lumineux ?
Embrechts, Jean-Jacques ULg

in Bulletin d'Acoustique (1994), 16

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See detailIntensities of the doublet-quadruplet intersystem transitions in C II and N III
Biémont, Emile ULg; Delahaye, F.; Zeippen, C. J.

in Journal of Physics : B Atomic Molecular & Optical Physics (1994), 27

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See detailRedox Mechanism For The Chaperone Activity Of Heat-Shock Proteins Hsp-60, Hsp-70 And Hsp-90 As Suggested By Hydrophobic Cluster-Analysis - Hypothesis
Callebaut, I.; Catelli, Mg.; Portetelle, Daniel ULg et al

in Comptes Rendus de l'Académie des Sciences. Série III, Sciences de la Vie (1994), 317(8),

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See detailMax Ophuls : le cristal et la tache
Belloi, Livio ULg

in Cinémathèque (1994), 6(automne),

Cette étude porte sur les quatre derniers films de Max Ophuls ("La Ronde", "Le Plaisir", "Madame de" et "Lola Montès") et s'attache à révéler, en eux, une forme de dilemme du visible (entre transparence ... [more ▼]

Cette étude porte sur les quatre derniers films de Max Ophuls ("La Ronde", "Le Plaisir", "Madame de" et "Lola Montès") et s'attache à révéler, en eux, une forme de dilemme du visible (entre transparence et opacité) que la modernité cinématographique inscrira résolument à son ordre du jour. [less ▲]

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See detailEffet du chargement et de la période de complémentation au pâturage sur les performances de taurillons finis en stabulation
Dufrasne, Isabelle ULg; Gielen, Marc ULg; Limbourg, Pierre et al

in Annales de Médecine Vétérinaire (1994), 138

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See detailFirst-principles calculations of dielectric and effective charge tensors in Barium Titanate
Ghosez, Philippe ULg; Gonze, X.; Michenaud, J. P.

in Ferroelectrics (1994), 153

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See detailConnection and frame design for economy
Anderson, D.; Colson, A.; Jaspart, Jean-Pierre ULg

in Bouwen met Staal (1994), n°117

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See detailKibaran A-type granitoids and mafic rocks generated by two mantle sources in a late orogenic setting (Burundi)
Tack, Luc; Liégeois, Jean-Paul ULg; Deblond, André et al

in Precambrian Research (1994), 68

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See detailHeterogeneous conversion of N2O5 to HNO3 in the post-Mount Pinatubo eruption stratosphere
Rinsland, Curtis P.; Gunson, Michaël R.; Abrams, M. C. et al

in Journal of Geophysical Research (1994), 99(D4), 8213-8219

Simultaneous stratospheric volume mixing ratio (VMR) profiles of dinitrogen pentoxide (N2O5) and nitric acid (HNO3) at sunrise between 25-degrees-N and 15-degrees-S latitude and profiles of HNO3 at sunset ... [more ▼]

Simultaneous stratospheric volume mixing ratio (VMR) profiles of dinitrogen pentoxide (N2O5) and nitric acid (HNO3) at sunrise between 25-degrees-N and 15-degrees-S latitude and profiles of HNO3 at sunset between 42-degrees-S and 53-degrees-S latitude have been derived from 0.01 cm-1 resolution infrared solar occultation spectra recorded 9 1/2 months after the massive eruption of the Mount Pinatubo volcano in the Philippine Islands. The measurements were obtained by the atmospheric trace molecule spectroscopy (ATMOS) Fourier transform spectrometer during the ATLAS 1 shuttle mission (March 24 to April 2, 1992). The measured HNO3 VMRs are higher at all altitudes and latitudes than corresponding values measured by the limb infrared monitor of the stratosphere (LIMS) instrument during the same season in 1979, when the aerosol loading was near background levels. The largest relative increase in the HNO3 VMR occurred near the equator at 30-km altitude, where the ATMOS/ATLAS 1 values are about a factor of 2 higher than the LIMS measurements. Two-dimensional model calculations show that the increase in HNO3 and the ATMOS/ATLAS 1 measurement of a steep decrease in the N2O5 VMR below 30 km can be explained by the enhanced conversion of N2O5 to HNO3 on the surfaces of the Mount Pinatubo sulfate aerosols. Our profile results demonstrate the global impact of the N2O5 + H2O --> 2HNO3 heterogeneous reaction in altering the partitioning of stratospheric odd nitrogen after a major volcanic eruption. [less ▲]

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See detailConséquences microcirculatoires et cellulaires de l'endotoxine
D'Orio, Vincenzo ULg

in Réanimation (1994), 1

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See detailDynamique du carbone inorganique des eaux de surface dans l'embouchure de l'Escaut
Frankignoulle, Michel; Biondo, Renzo ULg; Bouquegneau, Jean-Marie ULg et al

in Bulletin de la Société Royale des Sciences de Liège (1994), 61

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See detailHuman follicular dendritic cells in vitro
Tsunoda, R.; Heinen, Ernst ULg; Imai, Y. et al

in Dendritic Cells (1994), 4

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See detailSWIMMING PUPPY SYNDROME IN A LITTER OF BOUVIER-DES-FLANDRES
Poncelet, Luc; Gilbert, S.; Jauniaux, Thierry ULg et al

in Annales de Médecine Vétérinaire (1994), 138(2), 121-123

This paper describes the clinical, serologic, electrophysiologic and pathologic findings in three Bouvier des Flandres puppies exhibiting the swiming puppy syndrome. The puppies had no antibodies against ... [more ▼]

This paper describes the clinical, serologic, electrophysiologic and pathologic findings in three Bouvier des Flandres puppies exhibiting the swiming puppy syndrome. The puppies had no antibodies against distemper virus, T. gondii and N. caninum. A myopathy was suspected because spontaneous activities were disclosed in all muscle groups and muscles enzymes were elevated. However the pathologic findings were unable to confirm this hypothesis. [less ▲]

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See detailPlace of MALT in the immune defence system.
Heinen, Ernst ULg

in Advances in Experimental Medicine and Biology (1994), 355

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See detailChanges in glucose turnover parameters and improvement of glucose oxidation after 4-week magnesium administration in elderly noninsulin-dependent (type II) diabetic patients.
Paolisso, G.; Scheen, André ULg; Cozzolino, D. et al

in Journal of Clinical Endocrinology and Metabolism (1994), 78(6), 1510-4

The aim of the present study was to investigate the effects of magnesium supplementation on glucose uptake and substrate oxidation in noninsulin-dependent (type II) diabetic patients. Nine elderly non ... [more ▼]

The aim of the present study was to investigate the effects of magnesium supplementation on glucose uptake and substrate oxidation in noninsulin-dependent (type II) diabetic patients. Nine elderly non-obese noninsulin-dependent (type II) diabetic patients, treated by diet only, participated in the study, which was designed as randomized, double blind, and cross-over. Each patient was followed up for a prestudy period of 3 weeks before inviting him/her to receive placebo or magnesium supplementation (15.8 mmol/day) for 4 weeks. At the end of each treatment period, a euglycemic hyperinsulinemic glucose clamp with simultaneous D-[3-3H]glucose infusion and indirect calorimetry was performed. Magnesium supplementation resulted in significantly increased plasma and erythrocyte magnesium levels, whereas body weight and fasting plasma glucose did not change. In the last 60 min of the glucose clamp, insulin-mediated glucose disappearance, total body glucose disposal (24.5 +/- 0.4 vs. 28.2 +/- 0.7 mumol/kg.min; P < 0.005), and glucose oxidation (13.0 +/- 0.4 vs. 16.3 +/- 0.8 mumol/kg.min; P < 0.01) were increased after chronic magnesium supplementation. Endogenous glucose production, nonoxidative glucose disposal, lipid and protein oxidation, and insulin MCR were not affected. In conclusion, a 4-week magnesium supplementation improves insulin sensitivity and glucose oxidation in the course of a euglycemic-hyperinsulinemic glucose clamp in noninsulin-dependent diabetic patients. Long term studies are needed to determine whether magnesium supplementation is useful in the management of type II diabetes. [less ▲]

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See detailQue peut-on attendre des marqueurs immunohistochimiques du mélanome?
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Nouvelles Dermatologiques (1994), 13

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See detailExpected returns and volatility in european stock markets
Corhay, Albert ULg; Tourani-Rad, Alireza

in International Review of Economics and Finance (1994), 3(1), 45-56

The type of return generating process we test here on three European markets are GARCH and AR-GARCH in mean models with innovations that have either normal or student-t densities with time dependant ... [more ▼]

The type of return generating process we test here on three European markets are GARCH and AR-GARCH in mean models with innovations that have either normal or student-t densities with time dependant variances. These models are appealing in that they estimate time varying volatility in disturbances of stock returns series and ex-ante relationship between stock returns and volatility. Our results indicate that there is no statistically significant coefficient estimates for the volatility in the mean equation and that variance might not be appropriate as a measure of risk. Other proxies for risk should then be searched for. [less ▲]

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See detailThird Catalogue of stars measured in the Long-Term Photometry of Variables project.
Manfroid, Jean ULg; Sterken, C.; Cunow, B. et al

in European Southern Observatory Scientific Report (1994), 14

Not Available

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See detailCharacterization of a single prolactin (PRL) receptor in tilapia (Oreochromis niloticus) which binds both PRLI and PRLII
Auperin, B.; Rentier-Delrue, Françoise ULg; Martial, Joseph ULg et al

in Journal of Molecular Endocrinology (1994), 13(3), 241-51

In tilapia, there are two forms of prolactin (PRL) whose effects on sodium and chloride movements differ and depend on the living environment of the fish. To see whether different receptors or the same ... [more ▼]

In tilapia, there are two forms of prolactin (PRL) whose effects on sodium and chloride movements differ and depend on the living environment of the fish. To see whether different receptors or the same receptor mediates these different effects, we have characterized the specific binding of both forms of tilapia (ti)PRL in two osmoregulatory organs, the gill and kidney. Two recombinant tiPRLs were used for this analysis. The recombinant hormones had the same properties as the native hormones in a tilapia gill radioreceptor assay. Specific binding to gill and kidney membranes was increased by optimizing the quality of the tissue preparations (physiological state of fish, membrane preparation) and the incubation conditions (pH, salt concentrations, temperature, time). Under these optimized conditions, we detected only one class of high affinity PRL receptor in gill and kidney. Its binding affinity was higher for tiPRLI than for tiPRLII in both gill and kidney (for tiPRLI the respective affinity values were 2.9 and 2.3 x 10(10) per M, for tiPRLII they were 1.9 and 0.5 x 10(10) per M). In competition studies, tiPRLI was more potent, followed by tiPRLII and ovine (o)PRL. tiGH and oGH did not significantly displace either tiPRL. The receptor we have characterized thus recognizes quite specifically both tiPRLs. [less ▲]

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See detailLa crise suicidaire de l'adolescent, un appel à la vie
Malchair, Alain ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1994), 2

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See detailMalignant Hyperthermia and Severe Hypoglycemia after Reexposure to Halothane
Bichel, T.; Canivet, Jean-Luc ULg; Damas, Pierre ULg et al

in Acta Anaesthesiologica Belgica (1994), 45(1), 23-7

A four year child presented with an episode of malignant hyperthermia induced by reexposure to halothane. The episode was associated with early onset of a severe hypoglycemia and liver enzymatic ... [more ▼]

A four year child presented with an episode of malignant hyperthermia induced by reexposure to halothane. The episode was associated with early onset of a severe hypoglycemia and liver enzymatic perturbances. Etiology of these perturbances is hard to state precisely in this clinical context, but a hepatic toxicity of halothane and/or by dantrolene is considered. [less ▲]

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See detailBiostatistical studies of Western European allogamous populations of the Epipactis helleborine (L.) Crantz species group (Orchidaceae)
Tyteca, D.; Dufrêne, Marc ULg

in Systematic Botany (1994), 19(3), 424-442

[No abstract available]

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See detailGenetic diversity among some wild populations of lima bean (Phaseolus lunatus L.) proceeding from Central Valley of Costa Rica
Maquet, Alain; Wathelet, Bernard ULg; Dubois, Sophie et al

in Annual Report of the Bean Improvment Cooperative (1994)

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See detailTamoxifen restores the E-cadherin function in human breast cancer MCF-7/6 cells and suppresses their invasive phenotype
Bracke, M. E.; Charlier, Corinne ULg; Bruyneel, E. A. et al

in Cancer Research (1994), 54

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See detailDifferential Expression of the 67-Kd Laminin Receptor and 31-Kd Human Laminin-Binding Protein in Human Ovarian Carcinomas
van den Brule, F. A.; Berchuck, A.; Bast, R. C. et al

in European Journal of Cancer (1994), 30A(8), 1096-9

The expression of the 67-kD laminin receptor (67LR) and the 31-kD human laminin-binding protein (HLBP31), two proteins involved in cancer cell laminin interaction, was evaluated on 30 ovarian cancer ... [more ▼]

The expression of the 67-kD laminin receptor (67LR) and the 31-kD human laminin-binding protein (HLBP31), two proteins involved in cancer cell laminin interaction, was evaluated on 30 ovarian cancer specimens. Expression of the 67LR was increased (up to 2.5-fold, in 87% of the patients), while HLBP31 expression was downregulated in cancer cells compared with the normal tissue, as detected by northern blotting and immunohistochemistry. The immunohistochemical study demonstrated that the 67LR was significantly overexpressed (P < 0.05) in the group of patients whose cytoreductive surgery was suboptimal, and those with poor clinical outcome. No correlation was observed between HLBP31 expression and clinicopathological features. Increased expression of the 67LR appears to correlate with the invasive phenotype of ovarian cancer cells and suggests a role of the latter in ovarian cancer invasion. [less ▲]

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See detailL'inventaire forestier wallon: un outil de developpement regional
Rondeux, Jacques ULg

in Wallonie (1994), 21(34), 3-8

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See detailFIL2, an extracellular Leucine-Rich Repeat protein, is specifically expressed in Antirrhinum flowers.
Steinmayr, M.; Motte, Patrick ULg; Sommer, H. et al

in Plant Journal (The) (1994), 5(4), 459-67

The expression of the Antirrhinum gene FIL2 is affected in mutants of the homeotic transcription factor DEFICIENS. Northern and Western blot analyses showed that FIL2 in wild-type Antirrhinum flowers is ... [more ▼]

The expression of the Antirrhinum gene FIL2 is affected in mutants of the homeotic transcription factor DEFICIENS. Northern and Western blot analyses showed that FIL2 in wild-type Antirrhinum flowers is expressed weakly in the petals and more abundantly in the reproductive organs; the gene is active in the filaments and anthers of stamens, and in the stigma and transmitting tissue of the carpels. The FIL2 protein is glycosylated with high mannose type glycan chains and is located in the middle lamella of the extracellular matrix. The amino acid sequence contains 10 tandem repeats, the composition of which is similar to the Leucine-Rich Repeat (LRR) motif found in mammals, Drosophila and yeast. The possibility that FIL2 might be a component of a cellular signalling mechanism, involving LRR-mediated protein-protein interactions is discussed. [less ▲]

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See detailPathogenic Tracks in Fatigue Syndromes
Moutschen, Michel ULg; Triffaux, Jean-Marc ULg; Demonty, Jean ULg et al

in Acta Clinica Belgica (1994), 49(6), 274-89

This review analyses the recent literature devoted to two related fatigue syndromes: chronic fatigue syndrome (CFS) and acute onset postviral fatigue syndrome (PVFS). The articles are grouped into five ... [more ▼]

This review analyses the recent literature devoted to two related fatigue syndromes: chronic fatigue syndrome (CFS) and acute onset postviral fatigue syndrome (PVFS). The articles are grouped into five pathogenic tracks: infectious agents, immune system, skeletic muscle, hypothalamo-pituitary-adrenal (HPA) axis and psychiatric factors. Although a particular infectious agent is unlikely to be responsible for all CFS cases, evidence is shown that host-parasite relationships are modified in a large proportion of patients with chronic fatigue. Antibody titres against infectious agents are often elevated and replication of several viruses could be increased. Chronic activation of the immune system is also observed and could be due to the reactivation of persistent or latent infectious agents such as herpes viruses (i.e. HHV-6) or enteroviruses. It could also be favorised by an impaired negative feedback of the HPA axis on the immune system. A model is proposed where the abnormalities of the HPA axis are primary events and are mainly responsible for a chronic activation of the immune system which in turn induces an increased replication of several viruses under the control of cellular transcription factors. These replicating viruses together with cytokines such as TNF-alpha would secondarily induce functional disorders of muscle and several aspects of asthenia itself. [less ▲]

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See detailTnf-Alpha Is Involved in the Mechanism of Murine Thymic Lymphoma Prevention by Bone Marrow Grafting
Humblet, Chantal ULg; Deman, J.; Rongy, A. M. et al

in Advances in Experimental Medicine and Biology (1994), 355

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See detailDetailed Study of a Molecule in a Molecule N-Acetyl-L-Tryptophanamide in a Active-Site Model of Alpha-Chymotrypsin
Dive, Georges ULg; Dehareng, Dominique ULg; Ghuysen, Jean-Marie ULg

in Journal of the American Chemical Society (1994), 116(6), 2548-2556

Six complexes between a model active site of alpha-chymotrypsin (261 atoms) and N-acetyl-L-tryptophanamide (33 atoms) were optimized at the semiempirical AM1 level. In one of these complexes, a water ... [more ▼]

Six complexes between a model active site of alpha-chymotrypsin (261 atoms) and N-acetyl-L-tryptophanamide (33 atoms) were optimized at the semiempirical AM1 level. In one of these complexes, a water molecule was included. A detailed study at the geometric and energetic levels is presented. The discussion deals with the nature of the interaction, the effect of the environment, the ligand deformation, the backbone relaxation, the water molecule freedom, and the comparison with the molecular mechanics results. [less ▲]

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See detailLa régionalisation du droit pénal international
Flore, Daniel ULg; Thomas, F.

in Revue internationale de droit pénal (1994)

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See detailLa gynécologie dans les papyrus grecs de médecine
Marganne, Marie-Hélène ULg

in Acta Belgica Historiae Medicinae (1994), 7(4), 207-217

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See detailA fuzzy approach to the definition of standardized visibility in fog.
Boreux, Jean-Jacques ULg; Duckstein, Lucien

in Applied Mathematics and Computation (1994), 61(2-3), 287-299

The problem of defining the physical concept of standardized visibility is addressed by means of a fuzzy logic approach. Assuming that several hypotheses hold, it is possible to evaluate a standardized ... [more ▼]

The problem of defining the physical concept of standardized visibility is addressed by means of a fuzzy logic approach. Assuming that several hypotheses hold, it is possible to evaluate a standardized visibility Vk (or meteorological visual range) as the ratio of a psychometric coefficient k and the extinction coefficient σ of the aerosol. The main disadvantage of this relationship due to Koschmieder stems from the fact that the meteorological visual range can be very different from visibility estimated by a human observer with normal sight. This is particularly true during fog extinction coefficient supplied by a transmissometer and the corresponding visibility evaluated by an expert. Calculations are performed according to two different approaches. First, a so-called fuzzy hyperbolic model based on a distance defined by Bardossy et al is presented, yielding a crisp (nonfuzzy) value of the coefficient k. Next, we use the multiplication of two fuzzy numbers, taken as triangular, to build an average fuzzy number k that accounts for the different values found in the literature. The defuzzification of k confirms the result obtained by the first approach. [less ▲]

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See detailEvidence that two tilapia (Oreochromis niloticus) prolactins have different osmoregulatory functions during adaptation to a hyperosmotic environment
Auperin, B.; Rentier-Delrue, Françoise ULg; Martial, Joseph ULg et al

in Journal of Molecular Endocrinology (1994), 12(1), 13-24

Two forms of prolactin (tiPRLI and tiPRLII), with only 69% sequence identity, have been previously described in the cichlid fish tilapia (Oreochromis species). In the present study we have attempted to ... [more ▼]

Two forms of prolactin (tiPRLI and tiPRLII), with only 69% sequence identity, have been previously described in the cichlid fish tilapia (Oreochromis species). In the present study we have attempted to investigate the biological activity of these two prolactin forms during adaptation to a hyperosmotic environment. For this purpose, we have developed two highly sensitive (sensitivity: 0.05 ng/ml) and specific (cross-reactivity < 0.04%) radioimmunoassays for tiPRLI and tiPRLII, using recombinant hormones. When fish were directly transferred from fresh to brackish water, the measured levels of plasma tiPRLI and tiPRLII dropped abruptly until 12 h after transfer. Thereafter, plasma tiPRLII remained stable (around 0.5 ng/ml) until the end of the experiment, whereas plasma tiPRLI continued to decrease to undetectable levels. These different patterns of change are reflected in the calculated ratio of plasma tiPRLII to tiPRLI, which increased from 2-3 in fresh water-adapted fish to over 10 in fish which had spent 3 days or more in brackish water. The pituitary contents of tiPRLI and tiPRLII varied in a qualitatively similar fashion after transfer to brackish water. The tiPRLI content dropped continuously after 12 h, reaching one-twelfth of its initial level after 2 weeks. The pituitary tiPRLII content, on the other hand, did not decrease significantly until day 7, and after a 2-week exposure to brackish water it had only decreased by 50%. When injected into tilapia adapted to brackish water, both ovine prolactin and recombinant tiPRLI induced a clear dose-dependent ion-retaining effect. In contrast, the effect induced by tiPRLII treatment was markedly smaller and not dose-dependent. Northern blot analysis of tiPRL mRNAs using either a tiPRLI or a tiPRLII cDNA probe indicated the presence of two mRNAs differing in size: a 1.7 kb mRNA coding for tiPRLI and a 1.3 kb mRNA coding for tiPRLII. After transfer to brackish water, levels of the two mRNAs decreased similarly. The present study indicates that, in O. niloticus, the two forms of prolactin have different osmoregulatory roles during adaptation to brackish water. Accordingly, their synthesis are differentially regulated after transfer to a hyperosmotic environment, presumably at a post-transcriptional level. [less ▲]

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See detailThe use of acarbose in the prevention and treatment of hypoglycaemia.
Lefebvre, Pierre ULg; Scheen, André ULg

in European Journal of Clinical Investigation (1994), 24 Suppl 3

This paper reviews the use of acarbose in the prevention and treatment of hypoglycaemia. In diet- or sulfonylurea-treated patients, acarbose may reduce the incidence of late postprandial hypoglycaemia. In ... [more ▼]

This paper reviews the use of acarbose in the prevention and treatment of hypoglycaemia. In diet- or sulfonylurea-treated patients, acarbose may reduce the incidence of late postprandial hypoglycaemia. In insulin-treated patients, acarbose treatment usually requires reduction of the insulin dose; one study has shown that 100 mg acarbose at night significantly reduces the incidence of mid-evening and nocturnal hypoglycaemia. Several studies have suggested acarbose to be a useful adjunct to the management of reactive hypoglycaemia in the non-diabetic patients. Long-term prospective studies are still needed to document this last indication of acarbose or other alpha-glycosidase inhibitors. [less ▲]

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See detailCloning And Characterization Of Mn, A Human Tumor-Associated Protein With A Domain Homologous To Carbonic-Anhydrase And A Putative Helix-Loop-Helix Dna-Binding Segment
Pastorek, J.; Pastorekova, S.; Callebaut, I. et al

in Oncogene (1994), 9(10),

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See detailINTERNATIONAL-CONFERENCE ON BARBUS - PRESENT AND FUTURE - FOREWORD
BERREBI, P.; Poncin, Pascal ULg

in Bulletin Francais De La Peche Et De La Pisciculture (1994), (334), 167-168

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See detailDe réels progrès ont-ils été faits dans le traitement de l'ostéoporose ?
Reginster, Jean-Yves ULg; DEROISY, Rita ULg; Franchimont, P

in Medisearch (1994), 81

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See detailLe renouveau cosaque
Bachkatov, Nina ULg; Wilson, Andrew

in Transitions : Ex-Revue des Pays de L'est (1994), 35-1

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See detailON THE FUNCTIONAL-CHARACTERIZATION OF THE ANALYTIC WAVE-FRONT SET OF AN HYPERFUNCTION
Bastin, Françoise ULg; LAUBIN, P.

in Mathematische Nachrichten (1994), 166

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See detailEtude comparative de six systèmes d'immunodosage de la ferritine sérique au cours de maladies rhumatismales
Revenant, M. C.; Vernet, M.; Rymer, J. C. et al

in Eurobiologiste (L') (1994), XXVIII(2), 35-41

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See detailCharacterization and Tumorigenicity of Spheroids Composed of Pigmented or Non Pigmented B16 Melanoma Cells
Coucke, P. H.; Gillet, Marie-Claire ULg; Bonjean, K. A. et al

in In Vivo (Athens, Greece) (1994), 8(3, May-Jun), 333-8

A parental line of mouse B16 melanoma cells (B16) and two derived cloned lines, either pigmented (B16P) or non pigmented (B16NP), were cultured in vitro as spheroids. After 48 hrs, the pigmented cells ... [more ▼]

A parental line of mouse B16 melanoma cells (B16) and two derived cloned lines, either pigmented (B16P) or non pigmented (B16NP), were cultured in vitro as spheroids. After 48 hrs, the pigmented cells (B16, B16P) formed smaller and looser aggregates, with higher rates of cell proliferation and lower amounts of extracellular matrix as compared to B16NP spheroids. The three lines were more tumorigenic when inoculated subcutaneously as spheroids than as isolated cells. Furthermore, B16P or B16 spheroids developed richly vascularized subcutaneous tumors and metastases more rapidly than B16NP aggregates. After intravenous injection of spheroids, the measurement with an image analyzer of the area of sections in lung colonies indicated that B16P colonies were larger and more numerous than those induced by B16NP cells. [less ▲]

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See detailSignificance of soluble transferrin receptor
Beguin, Yves ULg; Loo, M.; R'Zik, Samir ULg et al

in Molecular Biology of Hematopoiesis (1994)

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See detailA semiautomated test apparatus for studying partner preference behavior in the rat.
Bakker, Julie ULg; van Ophemert, J.; Eijskoot, F. et al

in Physiology & Behavior (1994), 56(3), 597-601

A semiautomated three-compartment box (3CB) for studying partner preference behavior of rats is described. This apparatus automatically records the rat's time spent in each compartment, as well as the ... [more ▼]

A semiautomated three-compartment box (3CB) for studying partner preference behavior of rats is described. This apparatus automatically records the rat's time spent in each compartment, as well as the locomotor activity (i.e., the number of visits an animal pays to each compartment). Software was developed for calculating partner preference scores. Behavioral testing in the semiautomated 3CB, which is a modification of an earlier version, is less time consuming and less laborious. Three 3CBs can be observed simultaneously by two trained observers, and the behavioral interactions of three experimental animals with the stimulus animals can be observed and scored by hand. The use of the new apparatus was validated by studying adult partner preference behavior of neonatally ATD-treated male rats. The collected data fully corroborate previous results, obtained in the earlier version of the 3CB, again revealing the behavioral bisexual nature of these ATD males. A new finding was the much higher locomotor activity of the ATD males compared to controls. [less ▲]

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See detailDesign and modeling of new PAF antagonists - 1,4-bis-(3',4',5'-trimethoxybenzoyl)-2-substituted carbonyloxymethyl piperazines
Heymans, Françoise; Lamouri, Aazdine; Batt, Jean-Pierre et al

in Journal of Lipid Mediators and Cell Signalling (1994), 10(1-2), 153-154

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See detailShape processing and analysis using the calypter
Pirard, Eric ULg

in Journal of Microscopy (1994), 175(3), 214-221

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See detailLa formation des agents de santé scolaire dans le cadre du programme "Je mange bien à l'école"
Vandoorne, Chantal ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1994), (3),

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