References of "Article"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailA spline interpolation technique that preserves mass budgets
Delhez, Eric ULiege

in Applied Mathematics Letters (2003), 16(1), 17-26

The usual practice of forcing budget models by linear interpolations of mean data does not produce a forcing whose mean is the data value required. The usual third-order spline is modified into a fourth ... [more ▼]

The usual practice of forcing budget models by linear interpolations of mean data does not produce a forcing whose mean is the data value required. The usual third-order spline is modified into a fourth-order spline, called mc-spline, to cope with this issue. The technique provides a smooth and faithful continuous interpolation of the original data that is well suited for its graphical representations or for the forcing of numerical models. (C) 2002 Elsevier Science Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 81 (17 ULiège)
Full Text
Peer Reviewed
See detailIdentités et valeurs politiques : quelle homogénéité pour l'Eurégio ?
Jacquemain, Marc ULiege

in Fédéralisme - Régionalisme (2003)

Euregio Mosa-Rhine is a euregional structure that agregates Province of Liege and German-speaking belgian community (Belgium) Province of Limburg (Belgium), Province of South-Limburg (Netherlands) and ... [more ▼]

Euregio Mosa-Rhine is a euregional structure that agregates Province of Liege and German-speaking belgian community (Belgium) Province of Limburg (Belgium), Province of South-Limburg (Netherlands) and Regio Aachen (Germany). It is supposed to be an area with many commercial and cultural inter-relations. Throuth a survey led in 2002, the paper tries to assess cultural similitaries and differences between the five components at the level of social identity and political values. It shows a contrasted landscape where the two dutch-speaking parts being more individualist, the german part being more comunitarian and, at the heart, the province of Liege more materialist and egalitarian. [less ▲]

Detailed reference viewed: 34 (8 ULiège)
Full Text
Peer Reviewed
See detailHepatitis C: screening, treatment and prevention practical guidelines
Michielsen, P.; Brenard, R.; Bourgeois, N. et al

in Acta Gastro-Enterologica Belgica (2003), 66(1), 15-19

The standard treatment for patients with chronic hepatitis C is a 6-12-month combination therapy with interferon alpha and ribavirin. Induction treatment could result in a faster early decline of the ... [more ▼]

The standard treatment for patients with chronic hepatitis C is a 6-12-month combination therapy with interferon alpha and ribavirin. Induction treatment could result in a faster early decline of the hepatitis C virus (HCV) load and a better response rate. Naive chronically infected HCV patients (n = 454) were randomized into two arms to receive either induction treatment with interferon alpha 2b 5 million units (MU) subcutaneously (s.c.) daily during a period of 8 weeks (arm A); or treatment with interferon alpha 2b 5 MU s.c. three times a week (TIW) for a period of 8 weeks (arm B). After week 8, interferon treatment in both arms was 3 MU s.c. TIW for a total period of 12 months. In both arms, ribavirin (1000-1200 mg orally per day) was added at week 4. Induction treatment resulted in a higher virological response at week 8 of treatment (66%vs 47%; P < 0.01). However, response at the end of treatment and at 6 months follow-up was not different (53%vs 50%, 41%vs 33%). The occurrence of adverse events and the drop-out rate were similar in both arms. Although an early virological response is observed more frequently in the induction treatment, end of treatment response and sustained responses did not differ [less ▲]

Detailed reference viewed: 26 (0 ULiège)
Full Text
Peer Reviewed
See detailThree years of free-air CO2 enrichment (POPFACE) only slightly affects profiles of light and leaf characteristics in closed canopies of Populus.
Gielen, B; Liberloo, M; Bogaert, Jan ULiege et al

in Global Change Biology (2003), 9(7), 1022-1037

Detailed reference viewed: 5 (0 ULiège)
Full Text
Peer Reviewed
See detailDiagnostic différentiel en cas de présomption de myopathie atypique des équidés : illustration au travers de cas référés à la Faculté de Médecine Vétérinaire de l’Université de Liège au cours du printemps 2003
Votion, Dominique ULiege; Delguste, Catherine ULiege; Baise, Etienne ULiege et al

in Annales de Médecine Vétérinaire (2003), 147

Atypical myopathy is a frequently fatal disease inducing extensive and severe muscular damage, occurring during autumn and spring in grazing horses. The main features of the syndrome are the sudden onset ... [more ▼]

Atypical myopathy is a frequently fatal disease inducing extensive and severe muscular damage, occurring during autumn and spring in grazing horses. The main features of the syndrome are the sudden onset of non pathognomonic symptoms such as weakness, stiffness, sudation, recumbency and when observed, emission of dark urine. Confirmation of the diagnosis is of paramount importance since the disease can be recurrent on limited geographic area. This paper discusses the methodology applied on 7 clinical cases referred with a symptomatology suggestive of atypical myopathy to the Faculty of Veterinary Medicine at Liege University during the spring 2003. Two of those cases were confirmed for atypical myopathy. A presumption of atypical myopathy may be drawn on history and clinical signs. On living animals, the serum concentration of the creatinine phosphokinase enzyme is the most useful biochemical tests as an aid to diagnosis because it confirms the presence of muscle damage. Nevertheless, the definitive diagnosis requires the histological examination of specific muscular samples obtained post-mortem. [less ▲]

Detailed reference viewed: 240 (23 ULiège)
Full Text
Peer Reviewed
See detailSkin weathering: the face at the interface.
Pierard, Gérald ULiege

in Dermatology : International Journal for Clinical & Investigative Dermatology (2003), 207(3), 248-50

Detailed reference viewed: 18 (0 ULiège)
Full Text
Peer Reviewed
See detailEfficacité du piégeage, par les méthodes classiques, des coléoptères saproxyliques en Région wallonne (Belgique)
Lhoir, Jonathan; Fagot, Jean ULiege; Thieren, Yves et al

in Notes Fauniques de Gembloux (2003), 50

By definition, saproxylic fauna is discrete and hidden. The authors have tested several technics of trapping, in the beech forest of Rurbusch (Elsenborn village) and in the oak forest of Mohimont ... [more ▼]

By definition, saproxylic fauna is discrete and hidden. The authors have tested several technics of trapping, in the beech forest of Rurbusch (Elsenborn village) and in the oak forest of Mohimont (Daverdisse village). Both forests are caracterized by a large amount of dead wood standing and laying down. The trapping's results are presented, with regards on the different technics used, on the differences between sites, on the beetles families and their saproxylic behavior. [less ▲]

Detailed reference viewed: 52 (1 ULiège)
Full Text
Peer Reviewed
See detailDaily induction combination treatment with alpha 2b interferon and ribavirin or standard combination treatment in naive chronic hepatitis C patients. A multicentre randomized controlled trial
Van Vlierberghe, H.; Leroux-Roels, G.; Adler, M. et al

in Journal of Viral Hepatitis (2003), 10(6), 460-466

The standard treatment for patients with chronic hepatitis C is a 6-12-month combination therapy with interferon alpha and ribavirin. Induction treatment could result in a faster early decline of the ... [more ▼]

The standard treatment for patients with chronic hepatitis C is a 6-12-month combination therapy with interferon alpha and ribavirin. Induction treatment could result in a faster early decline of the hepatitis C virus (HCV) load and a better response rate. Naive chronically infected HCV patients (n = 454) were randomized into two arms to receive either induction treatment with interferon alpha 2b 5 million units (MU) subcutaneously (s.c.) daily during a period of 8 weeks (arm A); or treatment with interferon alpha 2b 5 MU s.c. three times a week (TIW) for a period of 8 weeks (arm B). After week 8, interferon treatment in both arms was 3 MU s.c. TIW for a total period of 12 months. In both arms, ribavirin (1000-1200 mg orally per day) was added at week 4. Induction treatment resulted in a higher virological response at week 8 of treatment (66%vs 47%; P < 0.01). However, response at the end of treatment and at 6 months follow-up was not different (53%vs 50%, 41%vs 33%). The occurrence of adverse events and the drop-out rate were similar in both arms. Although an early virological response is observed more frequently in the induction treatment, end of treatment response and sustained responses did not differ. [less ▲]

Detailed reference viewed: 33 (2 ULiège)
Full Text
Peer Reviewed
See detailUse of Hsf1(-/-) mice reveals an essential role for HSF1 to protect lung against cadmium-induced injury
Wirth, D.; Christians, E.; Li, Xiang ULiege et al

in Toxicology and Applied Pharmacology (2003), 192(1), 12-20

Cadmium (Cd) is known to activate heat shock (HS) response, which is characterized by overexpression of heat shock proteins (Hsps) under the control of heat shock factor 1 (HSF1). The potential protection ... [more ▼]

Cadmium (Cd) is known to activate heat shock (HS) response, which is characterized by overexpression of heat shock proteins (Hsps) under the control of heat shock factor 1 (HSF1). The potential protection provided by the HS response, induced by increasing the body temperature of animals before Cd exposure or by Cd itself, against pathophysiological changes occurring after Cd intranasal instillation (1 to 100 microg/mouse) was examined. HSF1-deficient mice were used to evaluate the role of this factor in lung protection. Cd instillation caused dose- and time-dependent changes in the respiratory pattern measured by plethysmography (Penh), and significant increases in lactate dehydrogenase (LDH) activity as well as macrophage and neutrophil counts in bronchoalveolar lavage fluids. HS preconditioning induced Hsp overexpression and reduced the Penh (-30%), LDH (-25%), and neutrophil (-55%) responses to subsequent administration of the highest Cd doses (50 and 100 microg) in wild-type mice. HSF1 deficiency abolished the HS response and its protective effect. In the absence of preconditioning, Hsf1(-/-) mice exhibited higher values of Penh (+70%) and LDH activity (+42%) compared with wild-type animals when exposed to the lowest Cd doses. Higher macrophage (+80%) and neutrophil counts (+115%) were recorded whatever the dose. Western blot analyses indicated that lung protection might be related to the kinetics of HSF1-dependent Hsp70 expression. Altogether, our data demonstrate that HS response elicited both by prior HS and by Cd itself moderates pulmonary injuries due to Cd instillation, and that HSF1 is a major mediator in this protection. [less ▲]

Detailed reference viewed: 3 (0 ULiège)
Full Text
Peer Reviewed
See detailAu delà de l’irrationalité : vers une psychologique du phénomène de harcèlement moral.
Geuzaine, Caroline; Faulx, Daniel ULiege

in Cahiers Internationaux de Psychologie Sociale (2003), 48

De prime abord, les situations de harcèlement moral dégagent une impression d’irrationalité intense (Geuzaine & Faulx, 2000). Depuis notre position d’observateur extérieur, nous sommes face à un ensemble ... [more ▼]

De prime abord, les situations de harcèlement moral dégagent une impression d’irrationalité intense (Geuzaine & Faulx, 2000). Depuis notre position d’observateur extérieur, nous sommes face à un ensemble d’éléments qui heurtent la logique. Du point de vue de celui qui s’en sent victime, d’abord : une personne vit une situation d’abus sur son lieu de travail, elle nous décrit, dans un flot de détails, les agissements qu’elle subit et nous percevons l’intensité de son angoisse. Les affects sont à l’avant-plan, intenses et souvent désespérés. La personne se sent persécutée, bafouée, démolie, et pourtant tente obstinément de continuer à fonctionner dans une situation insupportable. Pourquoi ? Du point de vue de l’organisation, ensuite : le harcèlement moral, entre autres conséquences dommageables, entrave la productivité, augmente l’absentéisme, génère des surcoûts importants et détériore la qualité des produits et des services. Si un fonctionnement optimal et une bonne gestion des ressources humaines semblent un objectif profitable à l’organisation, comment le harcèlement moral peut-il s’y développer ? Lorsque l’on tente d’intégrer le « harceleur» au système compréhensif, l’irrationnel est de nouveau à l’avant-plan. En effet, les raisons qui amènent cette personne à développer un mode relationnel persécutoire ont beau être logiquement justifiées (« je veille à la qualité du travail et promeus l’excellence ». «cette personne ne répond pas aux critères », « c’est de mon devoir de la sanctionner ,«c’est pour qu’elle apprenne »), il n’en sert pas moins, même involontairement, des fins totalement irrationnelles : mettre en échec puis détruire psychologiquement une personne et l’évacuer du système professionnel en invoquant sa propre responsabilité, son déséquilibre, son inadaptation au travail. Pourquoi ? Le but de cet article est de présenter un modèle d’analyse qui permette de dépasser l’impression d’irrationalité qui se dégage des situations de harcèlement moral. Nous verrons qu’il existe une logique sous-jacente au processus de harcèlement moral; logique certes subjective et biaisée, mais à la base d’un système de comportements et d’attentes très influent. Après avoir exposé quelques repères théoriques, nous présenterons notre recherche et nos postulats méthodologiques. La partie consacrée à nos résultats s’articulera autour de deux axes : la présentation de certaines régularités parmi les situations de harcèlement moral et une réflexion sur l’aide que l’on peut proposer aux personnes qui en sont victimes. [less ▲]

Detailed reference viewed: 147 (3 ULiège)
Full Text
Peer Reviewed
See detailRetreatment of hepatitis C non-responsive to interferon. A placebo controlled randomized trial of ribavirin monotherapy versus combination therapy with Ribavirin and Interferon in 121 patients in the Benelux [ISRCTN53821378]
Veldt, Bart J; Brouwer, Johannes T; Adler, Michael et al

in BMC Gastroenterology (2003), 3(1), 24

BACKGROUND: Evidence based medicine depends on unbiased selection of completed randomized controlled trials. For completeness it is important to publish all trials. This report describes the first large ... [more ▼]

BACKGROUND: Evidence based medicine depends on unbiased selection of completed randomized controlled trials. For completeness it is important to publish all trials. This report describes the first large randomised controlled trial where combination therapy was compared to placebo therapy and to ribavirin monotherapy, which has not been published until now. METHODS: One hundred and twenty one patients with chronic hepatitis C and elevated transaminases who did not respond to previous treatment with standard interferon monotherapy, were included from 16 centers in Belgium, the Netherlands and Luxembourg between 1992 and 1996. Patient poor-response characteristics were: genotype 1 (69%), HCV RNA above 2 x 10(6) copies/ml (55%) and cirrhosis (38%). Patients were randomized to 6 months combination therapy with interferon alpha-2b (3 MU tiw) and ribavirin (1000-1200 mg/day), 6 months ribavirin monotherapy (1000-1200 mg/day) or 6 months ribavirin placebo. The study was double blinded for the ribavirin/placebo component. One patient did not fit the entry criteria, and 3 did not start. All 117 patients who received at least one dose of treatment were included in the intention to treat analysis. RESULTS: At the end of treatment, HCV RNA was undetectable in 35% of patients on combination therapy and in none of the patients treated with ribavirin monotherapy or placebo. The sustained virological response rate at 6 months after therapy was 15% for patients treated with interferon and ribavirin.During the 6 months treatment period 13% of patients on interferon ribavirin combination therapy, 13% of patients on ribavirin monotherapy and 11% of patients on placebo withdrew due to side effects or noncompliance. At 24 weeks of treatment the mean Hb level was 85% of the baseline value, which means a mean decrease from 9.1 mmol/l to 7.8 mmol/l. The Hb levels at the end of treatment were not significantly different from patients treated with ribavirin monotherapy (p = 0.76). End of treatment WBC was significantly lower in patients treated with combination therapy, compared to ribavirin (p < 0.01) as well as for patients treated with ribavirin monotherapy compared to placebo (p < 0.01). DISCUSSION: This belated report on the only placebo controlled study of interferon ribavirin combination therapy in non responders to standard doses of interferon monotherapy documents the effectiveness, be it limited, of this approach as well as the dynamics of the effects on blood counts. [less ▲]

Detailed reference viewed: 30 (1 ULiège)
Full Text
Peer Reviewed
See detailApport à la connaisance du genre Rhizophagus Herbst, 1793 (Coleoptera: Clavicornia Monotomidae) en région wallonne (Belgique)
Thieren, Yves; Fagot, Jean ULiege; Lhoir, Jonathan et al

in Notes Fauniques de Gembloux (2003), 50

During a trapping year in two hardwood forests of Walloonia, the Rhizophagus reveale to be the most abundant saproxylic beetles. The authors give comments on the different species met, on the relations ... [more ▼]

During a trapping year in two hardwood forests of Walloonia, the Rhizophagus reveale to be the most abundant saproxylic beetles. The authors give comments on the different species met, on the relations between species and trapping methods and on the species activity during the six months trapping. Waiting for an exhaustive revision of the genera, a primary point is made on the Rhizophagus in Belgium and a prime list is given with a lot of ethological considerations. [less ▲]

Detailed reference viewed: 22 (1 ULiège)
Full Text
See detailLe gigantisme : Un mystère élucidé
Beckers, Albert ULiege

in Louvain Medical (2003), 122(6), 241-248

L'acromégalie a été décrite par Pierre Marie en 1886. Peu de temps après, il est devenu clair que le gigantisme et l'acromégalie ont la même étiologie: une hypersécrétion d'hormone de croissance, la ... [more ▼]

L'acromégalie a été décrite par Pierre Marie en 1886. Peu de temps après, il est devenu clair que le gigantisme et l'acromégalie ont la même étiologie: une hypersécrétion d'hormone de croissance, la plupart du temps par un adénome hypophysaire, produit un géant si elle a lieu avant l'âge adulte et un acromégale si elle survient après la puberté. Au cours du XXe siècle, cette affection sera caractérisée et divers traitements efficaces mis au point. A la fin du siècle, les mécanismes génétiques responsables de la maladie seront élucidés. [less ▲]

Detailed reference viewed: 67 (5 ULiège)
Full Text
See detailUn syndrome de Netherton atypique
EL HAYDERI, Lara ULiege; DEZFOULIAN, Bita ULiege; NIKKELS, Arjen ULiege

in Skin (2003), 16(5), 38

Detailed reference viewed: 21 (0 ULiège)
Full Text
Peer Reviewed
See detailPrediction of organoleptic and technological characteristics of pork meat by near infrared spectroscopy
Meulemans, A.; Dotreppe, Olivier ULiege; Leroy, Bernadette ULiege et al

in Sciences des Aliments (2003), 23(1), 159-162

Detailed reference viewed: 91 (6 ULiège)
Full Text
Peer Reviewed
See detailLa varicelle et le zona ou les mystères de la latence d'un virus et de sa réactivation
Rentier, Bernard ULiege

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2003), 158(3-4), 169-73174-5

Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features: chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological ... [more ▼]

Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features: chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological features of these diseases such as complications of chicken pox, viral latency in sensory ganglia and reactivation as shingles with concurrent and possibly subsequent prolonged pain, are the sequels of the invasion of the peripheral nervous system during primary infection. Prevention is achieved by vaccination with a live attenuated virus strain and therapy calls for specific antiviral agents. In many respects, vzv behaves differently from close relatives. In particular, viral latency in the nervous system is basically different from that of other Herpesviridae. The recent discovery of the expression of some viral regulatory proteins during latency, although it had always been considered that vzv latency was silent, and demonstration that these proteins are immunogenic open new avenues concerning the immune control of vzv reactivation. [less ▲]

Detailed reference viewed: 84 (9 ULiège)
Full Text
Peer Reviewed
See detailPrédiction de la composition de la carcasse et de la qualité de viande du Piétrain stress négatif par ultrasonographie en temps réel
Youssao, A. K. I.; Verleyen, Vincent ULiege; Michaux, Charles ULiege et al

in Annales de Médecine Vétérinaire (2003), 147(6), 403-410

The lean meat proportion and longissimus thoracis intramuscular fat percentage were predicted in negative-stress Pietrain pigs by real-time ultrasound using Pie Medical 200. The optimal probing site for ... [more ▼]

The lean meat proportion and longissimus thoracis intramuscular fat percentage were predicted in negative-stress Pietrain pigs by real-time ultrasound using Pie Medical 200. The optimal probing site for the estimation of carcass lean content percentage was first identified. The models for the prediction of carcass lean content proportion by ultrasound measurement were developed. Comparisons between Fat Lean Meter, ultrasonic device Piglog 105 and Pie Medical 200 were made for lean meat proportion estimation in Pietrain carcasses. The intramuscular fat percentage was predicted from the white pixel percentage in the longissimus thoracis ultrasound image [less ▲]

Detailed reference viewed: 66 (13 ULiège)
Full Text
Peer Reviewed
See detailDownregulation of putative tumor suppressor gene TSC-22 in human brain tumors.
Shostak, Kateryna ULiege; Dmitrenko, Vladimir V.; Garifulin, Oleg M. et al

in Journal of Surgical Oncology (2003), 82(1), 57-64

BACKGROUND AND OBJECTIVES: Our objective was to identify differentially expressed genes involved in the pathogenesis of glioblastoma multiforme (GBM). METHODS: Screening of arrayed human fetal brain and ... [more ▼]

BACKGROUND AND OBJECTIVES: Our objective was to identify differentially expressed genes involved in the pathogenesis of glioblastoma multiforme (GBM). METHODS: Screening of arrayed human fetal brain and human postnatal brain cDNA libraries was performed by differential hybridization with glioblastoma multiforme and human normal brain cDNAs. RESULTS: Repeated differential hybridization of more than 100 cDNA clones selected by primary screening and analysis of RNA from adult normal brain and glial tumors showed 16 nucleotide sequences differentially expressed between normal brain and brain tumors. Among others, decreased content in astrocytic tumors was determined for TSC-22 mRNA corresponding to cDNA in the ICRFp507J1041 clone from human fetal brain cDNA library. Northern blot hybridization of RNA from different human brain tumors showed very low amounts of TSC-22 mRNA in most investigated samples of GBM, anaplastic astrocytoma, and some other tumors. Complete lack of expression of TSC-22 occurred in one sample of anaplastic astrocytoma, as well as in meningioma, brain sarcoma, sarcomatous meningioma, and oligodendroglioma. The differential expression of TSC-22 gene was confirmed by semiquantitative RT-PCR in 15 samples of astrocytomas WHO grade II-IV and three samples of normal brain. CONCLUSIONS: Significantly decreased levels of TSC-22 mRNA in human brain and salivary gland tumors and antiproliferative role of TSC-22 strongly suggest a tumor suppressor role for TSC-22. J. [less ▲]

Detailed reference viewed: 15 (2 ULiège)
Full Text
Peer Reviewed
See detailCharacterization of hyperporous polyurethane-based gels by non-intrusive mercury porosimetry
Pirard, René ULiege; Rigacci, Arnaud; Marechal, Jacqueline ULiege et al

in Polymer (2003), 44(17), 4881-4887

Evaporative drying of polyurethane-based gels produces xerogels. Supercritical drying after replacement of interstitial liquid by supercritical CO2 produces aerogels. SEM micrographs show that both ... [more ▼]

Evaporative drying of polyurethane-based gels produces xerogels. Supercritical drying after replacement of interstitial liquid by supercritical CO2 produces aerogels. SEM micrographs show that both materials are made up of small size particles gathered up in filament-shaped, strongly cross-linked aggregates. Density measurements show that they both have a large pore volume. When submitted to mercury porosimetry, the behavior of these materials is similar to that of inorganic aerogels, as previously observed. Mercury does not penetrate the pore network, but the whole material is densified. The usual Washburn equation cannot be used to analyze the mercury porosimetry. A well-suited equation based on a buckling model of filament-shaped aggregates has been developed in order to determine the pore volume distribution of mineral dried gels. This equation is also valid for analyzing the texture of organic hyperporous materials like polyurethane dried nanoporous gel. (C) 2003 Elsevier Science Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 63 (19 ULiège)
Full Text
Peer Reviewed
See detailAfrique : crise de l’Université nationale, développement et institutionnalisation des inégalités
Poncelet, Marc ULiege

in Bulletin des Séances de l’Académie Royale des Sciences d’Outre-Mer = Mededelingen der Zittingen van de Koninklijke Academie voor Overzeese Wetenschappen (2003), 49 (2003-2)

The unbalanced growth, social instability and "lack of all" of african universities should not hide the deep dynamics of inequalities they project into the social construction of society

Detailed reference viewed: 19 (1 ULiège)
Full Text
Peer Reviewed
See detailRestart of lignification in micropropagated walnut shoots coincides with rooting induction
Bisbis, Badia; Kevers, Claire ULiege; Crèvecoeur, Michèle et al

in Biologia Plantarum (2003), 47(1), 1-5

The lignin content of walnut shoots did not change during in vitro shoot Multiplication. Lignin content started to increase as soon as shoots were passed to a rooting medium with auxin. Exogenous auxin ... [more ▼]

The lignin content of walnut shoots did not change during in vitro shoot Multiplication. Lignin content started to increase as soon as shoots were passed to a rooting medium with auxin. Exogenous auxin (applied for rooting) Caused a transient elevation of the endogenous free indoleacetic acid (IAA) content with a Simultaneous decrease of peroxidase activity. These events typically marked the completion of the rooting inductive phase (before any visible histological event. that is before the cell divisions beginnin- the rootin- initiation phase). This meant that either the given exogenous auxin or the endogenous IAA has served as signal for the stimulation of lignification. Continued increase of lignification in the shoots required completion of root formation; this increase indeed was slown down when root emergence did not occur. It was further shown that lionification varied conversely to the content of the Soluble Phenol Content. itself apparently being related to the activity of phenylalanine ammonia-lyase activity. [less ▲]

Detailed reference viewed: 79 (4 ULiège)
Full Text
Peer Reviewed
See detailNitric oxide synthase inhibition lowers activity of neurons with meningeal input in the rat spinal trigeminal nucleus
De Col, R.; Koulchitsky, Stanislav ULiege; Messlinger, K. B.

in Neuroreport (2003), 14(2), 229-32

Nitric oxide is thought to control transmitter release and neuronal activity in the spinal dorsal horn and the spinal trigeminal nucleus, where nociceptive information from extra- and intracranial tissues ... [more ▼]

Nitric oxide is thought to control transmitter release and neuronal activity in the spinal dorsal horn and the spinal trigeminal nucleus, where nociceptive information from extra- and intracranial tissues is processed. Extracellular impulse activity was recorded from neurons in the rat spinal trigeminal nucleus with afferent input from the cranial dura mater. In contrast to the inactive isomer D-NAME, infusion of the nitric oxide synthase inhibitor L-NAME (20 mg/kg) significantly reduced neuronal activity and increased systemic blood pressure. It is concluded that nitric oxide production contributes to the ongoing activity of sensitized neurons in the spinal trigeminal nucleus. The results suggest that nitric oxide may be involved in the generation and maintenance of primary headaches such as migraine. [less ▲]

Detailed reference viewed: 15 (0 ULiège)
Full Text
Peer Reviewed
See detailMetabolising risk: food scares and the un/re-making of Belgian beef
Stassart, Pierre M ULiege; Whatmore, Sarah J.

in Environment & Planning A (2003), 35

In this paper we explore the event of foodscares as an example of what Callon calls 'hot situations', in which the landscape of competing knowledge claims is at its most molten, and alternative production ... [more ▼]

In this paper we explore the event of foodscares as an example of what Callon calls 'hot situations', in which the landscape of competing knowledge claims is at its most molten, and alternative production and consumption practices galvanise new modes of sense-making against the market and state-sanctioned rationalities of industrialisation. Through a case study of the Belgian cooperative Coprosain and its meat products, we examine the 'stuff' of food as a ready messenger of connectedness and affectivity in which 'risk' is transacted as a property both of the growing distance between the spaces of production and consumption and of the enduring metabolic intimacies between human and nonhuman bodies. [less ▲]

Detailed reference viewed: 571 (22 ULiège)
Full Text
Peer Reviewed
See detailL'importance économique du bénévolat associatif en Belgique
Mertens de Wilmars, Sybille ULiege

in Non Marchand : Management, Droit et Finance (2003), (11), 9-22

Detailed reference viewed: 21 (0 ULiège)
Full Text
Peer Reviewed
See detailA note on the age of radioactive tracers
Delhez, Eric ULiege; Deleersnijder, Eric; Mouchet, Anne ULiege et al

in Journal of Marine Systems (2003), 38(3-4), 277-286

wThe age of a water mass is often estimated experimentally using the radio-age computed from the distribution of a radioactive tracer (radiocarbon, helium-tritium). Deleersnijder et al. [J. Mar. Syst. 28 ... [more ▼]

wThe age of a water mass is often estimated experimentally using the radio-age computed from the distribution of a radioactive tracer (radiocarbon, helium-tritium). Deleersnijder et al. [J. Mar. Syst. 28 (2001) 229.] have shown that the radio-age underestimates the age of the water and is larger than the age of the radioactive tracer used for its evaluation. This result is generalized here to radio-ages computed from the ratio of two radioactive tracers. The differences between the different ages are also studied analytically and numerically as functions of the decay rate of the radioactive tracers. For small decay rates, the difference between the age of the water mass and the radio-age is shown to be proportional to the decay rate. It depends also on the level of mixing in the system; even radioactive tracers with small decay rates can provide poor estimates of the age of the water mass in a strongly diffusive flow. For small half lives, both the radio-age and the age of radioactive tracers decrease as the inverse of the square root of the decay rate. The same analysis applies to some extent to the estimates of the age of a water mass from stable tracers with known time dependent sources (e.g. chloroflurocarbons). (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

Detailed reference viewed: 40 (17 ULiège)
Full Text
Peer Reviewed
See detailAllons-nous mourir bronzés ou ostéomalaciques? Le dilemme de la protection solaire entre Charybde et Scylla
Uhoda, I.; Crestey, M.; Pierard, Claudine ULiege et al

in Revue Médicale de Liège (2003), 58(5), 307-9

Sun is at the origin of life. It can also be responsible for death. In the past decades cutaneous melanoma killed more and more young adults. Currently, the disease still progresses in the population, but ... [more ▼]

Sun is at the origin of life. It can also be responsible for death. In the past decades cutaneous melanoma killed more and more young adults. Currently, the disease still progresses in the population, but survival increases hopefully. Sun is pointed out as the main culprit. Hence, protection against harmful effects of ultraviolets is mandatory. However, preventive measures to be taken generate heated scientific argument. Sunlight exposure particularly in moderation is indeed necessary for health through vitamin D3 synthesis and psychological effects on wellbeing. Vitamin D3 provides numerous biological effects, particularly on bone calcification and also by inhibiting proliferation and migration of malignant cells including melanoma cells. Hence, we are facing the dilemma between too much and too little ultraviolet light exposure. Anyway, one cannot advocate that people lie in the sun until they burn or until they turn a rich brown complexion. [less ▲]

Detailed reference viewed: 108 (0 ULiège)
Full Text
Peer Reviewed
See detailSolar-blind diamond detectors for LYRA, the solar VUV radiometer on board PROBA II
Benmoussa, A.; Hochedez, J. F.; Schmutz, W. K. et al

in Experimental Astronomy (2003), 16(3), 141-148

Fabrication, packaging and experimental results on the calibration of metal-semiconductor-metal (MSM) photodetectors made on diamond are reported. LYRA (Lyrnan-alpha RAdiometer onboard PROBA-2) will use ... [more ▼]

Fabrication, packaging and experimental results on the calibration of metal-semiconductor-metal (MSM) photodetectors made on diamond are reported. LYRA (Lyrnan-alpha RAdiometer onboard PROBA-2) will use diamond detectors for the first time in space for a solar physics instrument. A set of measurement campaigns was designed to obtain the XUV-to-VIS responsivity of the devices and other characterizations. The measurements of responsivity in EUV and VUV spectral ranges (40-240 nm) have been carried out by the Physkalisch-Technische Bundesanstalt (PTB) in Germany at the electron storage ring BESSY II. The longer wavelength range from 210 to 1127 nm was measured with monochromatic light by using a Xe-lamp at IMO-IMOMEC. The diamond detectors exhibit a photoresponse which lie in the 35-65 mA/W range at 200 nm (corresponding to an external quantum efficiency of 20-40%) and indicate a visible rejection ratio (200-500 nm) higher than four orders of magnitude. [less ▲]

Detailed reference viewed: 15 (2 ULiège)
Peer Reviewed
See detailBarotrauma-induced tension pneumoperitoneum.
Canivet, Jean-Luc ULiege; Yans, Th; Piret, Sonia ULiege et al

in Acta Anaesthesiologica Belgica (2003), 54(3), 233-6

We report the case of a massive tension-pneumoperitoneum developing immediately after starting mechanical ventilation (barotrauma). Careful analysis of CT-data provided meaningful informations in ... [more ▼]

We report the case of a massive tension-pneumoperitoneum developing immediately after starting mechanical ventilation (barotrauma). Careful analysis of CT-data provided meaningful informations in assessing the non surgical pulmonary source of pneumo peritoneum. [less ▲]

Detailed reference viewed: 61 (5 ULiège)
Full Text
Peer Reviewed
See detailRealization of electroplating molds with thick positive SPR 220-7 photoresist
Kukharenka, Elena; Kraft, Michael ULiege

in Journal of Materials Science: Materials in Electronics (2003), 14(5-7), 319--322

Detailed reference viewed: 10 (0 ULiège)
Full Text
Peer Reviewed
See detailCarbohydrates and resistance to Phytophthora infestans in potato plants
Evers, Danièle; Dommes, Jacques ULiege; Hausman, Jean-François

in Acta Physiologiae Plantarum (2003), 25(2), 171-178

Plants generally deal with biotic or abiotic stresses by altering components as for example cell wall constituents and metabolites. Infection by Phytophthora infestans, the causal agent of late blight ... [more ▼]

Plants generally deal with biotic or abiotic stresses by altering components as for example cell wall constituents and metabolites. Infection by Phytophthora infestans, the causal agent of late blight, constitutes a stress condition for the plants and they react to it with changes arising in their metabolism depending on the resistance level of the plants. The present work compares two potato hybrids differing in their level of horizontal resistance to late blight. Carbohydrate content in stems and leaves of infected and uninfected plants was determined by HPLC. Some carbohydrates accumulated in the stems of the resistant hybrid infected by P. infestans, whereas they remained unchanged in the susceptible hybrid. On the other hand, in the leaves, these carbohydrates accumulated only in the infected susceptible hybrid. [less ▲]

Detailed reference viewed: 32 (2 ULiège)
Full Text
Peer Reviewed
See detailIntérêt du monitoring continu du glucose interstitiel chez le patient diabétique de type 1
RADERMECKER, Régis ULiege; Sélam, Jean-Louis; SCHEEN, André ULiege

in Revue Médicale Suisse (2003), 61

Detailed reference viewed: 15 (3 ULiège)
Full Text
Peer Reviewed
See detailPreparation of nanosized barium zirconate powder by thermal decomposition of urea in an aqueous solution containing barium and zirconium, and by calcination of the precipitate
Boschini, Frédéric ULiege; Robertz, B.; Rulmont, André ULiege et al

in Journal of the European Ceramic Society (2003), 23(16), 3035-3042

The synthesis of barium zirconate was initiated by urea induced homogeneous precipitation followed by a "low temperature" thermal treatment. The kinetic of the reaction and the optimum urea/cation ratio ... [more ▼]

The synthesis of barium zirconate was initiated by urea induced homogeneous precipitation followed by a "low temperature" thermal treatment. The kinetic of the reaction and the optimum urea/cation ratio have been determined by means of X-ray diffraction and Inductive Coupled Plasma analyses. It has been demonstrated that an amorphous zirconium hydrated oxide starts to precipitate followed by the precipitation of barium carbonate. A calcination at 1200 degreesC during 2 h gives rise to the formation of a pure barium zirconate phase. Microstructural characterisations have been performed in order to evaluate the sintering behaviour. Dilatometric measurements, coupled with scanning electron microscopy analyses clearly indicate that barium carbonate decomposition process leads to the formation of internal porosity which severely limits the density of the material, even if a sintering was performed at 1500 degreesC. A careful control of the heating profile seems to be necessary in order to produce dense materials. (C) 2003 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 56 (4 ULiège)
Full Text
Peer Reviewed
See detailLes échecs électifs en mathématique : un regard inspiré de la didactique.
Schneider-Gilot, Marguerite ULiege

in Mathématique et Pédagogie (2003), 140

Detailed reference viewed: 24 (0 ULiège)
Full Text
Peer Reviewed
See detailSymetrie et reproductibilite temporelle des donnees neurographiques.
Bouquiaux, Olivier ULiege; Horward, A.; Wang, François-Charles ULiege

in Neurophysiologie Clinique = Clinical Neurophysiology (2003), 33(4), 185-95

The aims of the present study are to document side-to-side differences and temporal variability, between two trials (T1 and T2 at a time interval of 3 months) of nerve conduction measurements collected ... [more ▼]

The aims of the present study are to document side-to-side differences and temporal variability, between two trials (T1 and T2 at a time interval of 3 months) of nerve conduction measurements collected from 30 healthy subjects (mean age 22 +/- 2 years). METHODS: The protocol at T1 consisted of motor nerve conduction studies of median, ulnar, peroneal and tibial nerves bilaterally, with measurement of (a) motor response size (amplitude and area); (b) terminal latency; (c) minimal, mean and maximal F-wave latency; (d) motor conduction velocity; and (e) F-wave occurrence. T1 also involved sensory nerve conduction studies of median, ulnar, radial, lateral and medial cutaneous, sural and superficial peroneal nerves bilaterally, with measurement of sensory potential size (amplitude and area) and computation of sensory conduction velocity. The protocol at T2 consisted of identical measurements from the dominant side. RESULTS AND CONCLUSION: There was a negative relationship between the variability of parameters evaluating nervous conduction and the length of the nerve segment under study. Thus, the smallest side-to-side and temporal variabilities are measured for minimal F-wave latencies (on average 2-3%). The limits of symmetry and temporal variability are particularly useful for diagnosis of unilateral peripheral neuropathy or neurophysiological follow-up of patients with neuropathy, when the variability of the parameter under study is weak and when there is a high correlation between values recorded on the left and on the right or at T1 and T2. This was the case for motor response size of tibial and ulnar nerves, sensory potential size of radial nerve and minimal F-wave latencies from each studied motor nerve. [less ▲]

Detailed reference viewed: 26 (2 ULiège)
Full Text
Peer Reviewed
See detailRéférences et issues des accouchements au Kivu, République démocratiquedu Congo
Mugisho, E; Dramaix, M; Porignon, Denis ULiege et al

in Revue d'Epidémiologie et de Santé Publique = Epidemiology and Public Health (2003), 51(2), 237-244

BACKGROUND: The process of referral between the first and the second level of the health system in the Democratic Republic of Congo is poorly understood. This report intends to study the association ... [more ▼]

BACKGROUND: The process of referral between the first and the second level of the health system in the Democratic Republic of Congo is poorly understood. This report intends to study the association between the referral and the hospital perinatal outcomes. METHODS: Delivery outcomes in a retrospective cohort of 1162 women admitted between June 95 and May 96, in two referral hospitals in Kivu were analyzed according to the referral status and the women's characteristics. RESULTS: Forty-three percent (n=492)of women admitted, corresponding to 2.3% of expected pregnant women, were referred. Referred women had higher risks of obstetrical complications (OR=2.0; CI95%: 1.3-3.1) and intervention (OR=1.5; CI95%: 1.0-2.3) and similar risks of low birth weight and perinatal mortality. Women with complications during the antenatal period had a double risk of intervention and perinatal mortality. The risk of obstetrical intervention was lower when women had attended 2 visits (OR=0.5; CI95%: 0.3-0.8); the risk of low birth weight was lowest only for mothers who had attended one visit (OR=0.5; CI95%: 0.3-0.9). Distance > or =90 minutes walking from home to hospital raised the risk of obstetrical complication (OR=1.7; CI95%: 1.1-2.5), the risk of obstetrical intervention (OR=1.5; CI95%: 1.0-2.1), and the risk of perinatal mortality (OR=1.6; CI95%: 1.0-2.7). Late admission raised the risk of perinatal mortality (OR=1.8; CI95%: 1.2-2.9) and lowered the risk of obstetrical complication (OR=0.7; CI95%: 0.5-1.0). Part payment of care was associated with higher risks of low birth weight (OR=1.9; CI95%: 1.3-2.9), perinatal mortality (OR=2.2; CI95%: 1.4-3.5) and obstetrical intervention (OR=2.4; CI95%: 1.7-3.4). CONCLUSION: These results suggest a deficit of referred cases considering that 15% of pregnant women in the area covered by the referral hospitals should have been referred. They confirm the negative influence of economic and geographic constraints on the delivery outcomes. They point out the relevance of making reorganization of the referral system a priority. [less ▲]

Detailed reference viewed: 12 (0 ULiège)
Full Text
Peer Reviewed
See detailProsthetic vascular infection complicated or not by aortoenteric fistula: comparison of treatment with and without cryopreserved allograft (homograft).
Lavigne, Jean-Paul ULiege; Postal, Alain ULiege; Kolh, Philippe ULiege et al

in European Journal of Vascular and Endovascular Surgery (2003), 25(5), 416-23

OBJECTIVES: in patients with vascular prosthesis infection, to compare surgical outcome and long-term results of cryopreserved allograft implantations to conventional surgery. DESIGN: retrospective study ... [more ▼]

OBJECTIVES: in patients with vascular prosthesis infection, to compare surgical outcome and long-term results of cryopreserved allograft implantations to conventional surgery. DESIGN: retrospective study. MATERIAL AND METHODS: two asynchronous series of 44 [series I: 1980-1994; 8 patients with aortoenteric fistula (AEF)] and 22 (series II: 1994-1997; 4 patients with AEF) patients were treated for prosthesis infection. All patients had prosthesis excision. In series I, there were 4 in situ reparations, 26 extra-anatomic bypass, 13 excision only, and one death at laparotomy. In series II, in situ cryopreserved allografts were implanted in all patients. RESULTS: operative mortality was 16% in series I and 13.6% in series II. For AEF patients, mortality was 37% in series I and 50% in series II. Among hospital survivors, infection-related late mortality was 13.5% in series I and 5% in series II. For AEF patients, late mortality was 20% in series I and 50% in series II. Incidence of reoperations was 54% in series I and 10.5% in series II (p<0.01). Hospital stay was 47.2+/-26.4 days in series I and 16.6+/-11.5 days in series II (p<0.001). CONCLUSIONS: compared to conventional treatment, incidence of reoperations and length of hospital stay are significantly decreased after cryopreserved allograft implantation. However, closure of aortic stump and extra-anatomic bypass gives better results for patients with AEF. [less ▲]

Detailed reference viewed: 107 (1 ULiège)
Full Text
Peer Reviewed
See detailLe médecin, la trousse et le livre dans le monde gréco-romain
Marganne, Marie-Hélène ULiege

in Papyrologica Lupiensia (2003), 12

Detailed reference viewed: 78 (11 ULiège)
Full Text
Peer Reviewed
See detailE-service quality expectations: a case study
Van Riel, Allard ULiege; Semeijn, Janjaap; Janssen, Wendy

in Total Quality Management & Business Excellence (2003), 14(4), 437-450

Detailed reference viewed: 158 (2 ULiège)
Full Text
Peer Reviewed
See detailElectroplating moulds using dry film thick negative photoresist
Kukharenka, Elena; Farooqui, Mateen M.; Grigore, L. et al

in Journal of Micromechanics and Microengineering (2003), 13(4), 67-74

This paper reports on progress on the feasibility of fabricating moulds for electroplating using Ordyl P-50100 (negative) acrylate polymer based dry film photoresist, commercially available from Elga ... [more ▼]

This paper reports on progress on the feasibility of fabricating moulds for electroplating using Ordyl P-50100 (negative) acrylate polymer based dry film photoresist, commercially available from Elga Europe (http://www.elgaeurope.it). We used this photoresist as an alternative to SU8 negative epoxy based photoresist, which is very difficult to process and remove after electroplating (Lorenz et al 1998 Microelectron. Eng. 41/42 371–4, Eyre et al 1998 Proc. MEMS’98 (Heidelberg) (Piscataway, NJ: IEEE) pp 218–22). Ordyl P-50100 is easy to work with and can be easily removed after processing. A single layer of Ordyl P-50100 was deposited by lamination up to 20 µm thickness. Thicker layers (200 µm and more) can be achieved with multilayer lamination using a manual laminator. For our applications we found that Ordyl P-50100 dry film photoresist is a very good alternative to SU8 for the realization of 100 µm high moulds. The results presented will open up new possibilities for low-cost LIGA-type processes for MEMS applications. [less ▲]

Detailed reference viewed: 21 (0 ULiège)
Full Text
Peer Reviewed
See detailLa responsabilité extra-contractuelle des dirigeants de sociétés
Caprasse, Olivier ULiege

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2003)

Detailed reference viewed: 54 (8 ULiège)
Full Text
Peer Reviewed
See detailLes apports du projet Johns Hopkins dans la statistique du non-marchand
Mertens de Wilmars, Sybille ULiege

in Non Marchand : Management, Droit et Finance (2003), (11), 29-38

Detailed reference viewed: 20 (0 ULiège)
Full Text
Peer Reviewed
See detailLe pimecrolimus topique (Elidel).
Quatresooz, Pascale ULiege; Fumal, I.; Pierard, Claudine ULiege et al

in Revue Médicale de Liège (2003), 58(3), 168-71

Pimecrolimus inhibits some specific steps of the Th1 and Th2 immune reactions. It belongs to the class of ascomycin macrolactams. The topical drug formulation targets cutaneous inflammation, more ... [more ▼]

Pimecrolimus inhibits some specific steps of the Th1 and Th2 immune reactions. It belongs to the class of ascomycin macrolactams. The topical drug formulation targets cutaneous inflammation, more particularly lymphocytes and mast cells without impairing systemic immunosurveillance. Topical applications are indicated for treating atopic dermatitis. In this indication, it represents an alternative or an adjuvant drug to topical corticosteroids. The treatment of other dermatoses could also benefit from pimecrolimus. [less ▲]

Detailed reference viewed: 38 (1 ULiège)
Full Text
Peer Reviewed
See detailElectronic interface design for an electrically floating micro-disc
Gindila, Mircea V.; Kraft, Michael ULiege

in Journal of Micromechanics and Microengineering (2003), 13(4), 11-16

The design of an electronic interface for an electrically floating micro-disc is presented. The system, based on a second order electromechanical – modulator, can be used as a multi-axis capacitive ... [more ▼]

The design of an electronic interface for an electrically floating micro-disc is presented. The system, based on a second order electromechanical – modulator, can be used as a multi-axis capacitive accelerometer with the proof mass levitated by electrostatic forces. A synchronous detection scheme, used to sense the position of the proof mass, has been designed, simulated in PSpice TM and successfully implemented on a PCB. The interface contains a differential pick-off with no ohmic connection to the proof mass, which distinguishes the circuit from typical sensing circuits for MEMS capacitive accelerometers. A noise analysis of the pick-off circuit was performed, and an electronic equivalent model of the sensing circuit has been developed and used to analyse the linearity of its transfer function. The linearity of the sensing circuit was confirmed experimentally using the PCB implementation. [less ▲]

Detailed reference viewed: 21 (1 ULiège)
Full Text
Peer Reviewed
See detailResolution of chylothorax after resection of rib chondroma in a dog
Watine, Séverin; Hamaide, Annick ULiege; Peeters, Dominique ULiege et al

in Journal of Small Animal Practice (2003), 44(12), 546-549

A six-year-old, male dobermann was presented with a history of dyspnoea and bouts of coughing. Radiography and computed tomography of the thorax showed pleural effusion and a well-circumscribed, calcified ... [more ▼]

A six-year-old, male dobermann was presented with a history of dyspnoea and bouts of coughing. Radiography and computed tomography of the thorax showed pleural effusion and a well-circumscribed, calcified mass of 10 cm in diameter, appearing to originate from the left first rib. Thoracocentesis revealed that the pleural fluid was chylous in nature. An inclsional biopsy was performed, which gave a histological diagnosis of chondroma. Resolution of the chylothorax after en-bloc surgical removal of the tumour suggested that the rib tumour was the initiating cause of the chylothorax. Seventeen months later, rib neoplasia recurred without pleural effusion, and was removed successfully. To the authors' knowledge, rib chondroma, which is an unusual tumour in dogs, has not been previously documented as a cause of chylothorax. [less ▲]

Detailed reference viewed: 56 (3 ULiège)
Full Text
Peer Reviewed
See detailApproximation algorithms for the design of SDH/SONET networks
Brauner, Nadia; Crama, Yves ULiege; Finke, Gerd et al

in RAIRO : Operations Research = Recherche Opérationnelle (2003), 37(4, OCT-DEC), 235-247

In this paper, a graph partitioning problem that arises in the design of SONET/SDH networks is defined and formalized. Approximation algorithms with performance guarantees are presented. To solve this ... [more ▼]

In this paper, a graph partitioning problem that arises in the design of SONET/SDH networks is defined and formalized. Approximation algorithms with performance guarantees are presented. To solve this problem efficiently in practice, fast greedy algorithms and a tabu-search method are proposed and analyzed by means of an experimental study. [less ▲]

Detailed reference viewed: 77 (6 ULiège)
Full Text
Peer Reviewed
See detailMarchés immobiliers résidentiels et étalement urbain contraint. L'accessibilité au logement au sein de la région métropolitaine bruxelloise
Dubois, O.; Halleux, Jean-Marie ULiege

in Belgeo (2003), (3), 303-327

The release of mobility constraints has facilitated urban sprawl, i.e. the increasing spatial dissociation between urban cores and implantation sites of households and economic activities. The aim of this ... [more ▼]

The release of mobility constraints has facilitated urban sprawl, i.e. the increasing spatial dissociation between urban cores and implantation sites of households and economic activities. The aim of this paper about the Walloon part of the Brussels metropolitan region is to analyse how housing market constraints reinforce the trend towards residential sprawl. Based on an analysis of the financial accessibility to both, the market for new housings and the market for pre-existing housings, it is here the influence of the price level decreasing with the distance from Brussels which is taken into account. Due to their limited financial resources and to this price gradient, many households are obliged to settle on remote sites in order to acquire their property goods. In relation to this phenomenon, it appears that, from a spatial as well as from a social point of view, the Brussels urban system is not able to settle the metropolitan growth on an adapted way. Indeed, new residential locations reinforce the increasing dissociation between work places and living places, which leads to a useless increase in mobility costs as well as a serious accentuation of socio-spatial segregations. [less ▲]

Detailed reference viewed: 257 (31 ULiège)
Full Text
Peer Reviewed
See detailHC gp-39 gene is upregulated in glioblastomas.
Shostak, Kateryna ULiege; Labunskyy, Vyacheslav; Dmitrenko, Vladimir et al

in Cancer Letters (2003), 198(2), 203-10

Public databases of the Cancer Genome Anatomy Project were used to quantify the relative gene expression levels in glioblastoma multiforme (GBM) and normal brain by Serial Analysis of Gene Expression ... [more ▼]

Public databases of the Cancer Genome Anatomy Project were used to quantify the relative gene expression levels in glioblastoma multiforme (GBM) and normal brain by Serial Analysis of Gene Expression (SAGE). Analysis revealed HC gp-39 among the genes with the most pronounced changes of expression in tumor cells. Northern hybridization confirmed the results of computer analysis and showed that enhanced expression of the HC gp-39 gene was mainly in GBMs and occasionally in anaplastic astrocytomas. Neither SAGE nor Northern analysis revealed the presence of HC gp-39 mRNA in the glioblastoma cell line, thus the detection of increased quantities of this mRNA in GBMs may be associated with activated macrophages. Since the numbers of infiltrating macrophages and small vessel density are higher in glioblastomas than in anaplastic astrocytomas or astrocytomas, the HC gp-39 gene can be used as a molecular marker in the analysis of malignant progression of astrocytic gliomas. [less ▲]

Detailed reference viewed: 17 (2 ULiège)
Full Text
See detailLa ménopause et l'outrage du temps sur la peau et ses phanères.
Pierard, Gérald ULiege; Franchimont, Claudine ULiege

in Gynécologie - Obstétrique Pratique (2003), 155

Detailed reference viewed: 51 (1 ULiège)
Full Text
Peer Reviewed
See detailXylanase Production By Penicillium Canescens 10-10c In Solid-State Fermentation
Bakri, Y.; Jacques, Philippe ULiege; Thonart, Philippe ULiege

in Applied Biochemistry and Biotechnology (2003), 105

Detailed reference viewed: 19 (5 ULiège)
Full Text
Peer Reviewed
See detailP2X1-mediated ERK2 activation amplifies the collagen-induced platelet secretion by enhancing myosin light chain kinase activation.
Oury, Cécile ULiege; Toth-Zsamboki, Emese; Cornelissen, Heidi et al

in Journal of Biological Chemistry (2003)

This study shows that, at low doses of collagen, glycoprotein VI activation leads to early protein kinase C- and MLC kinase-dependent platelet degranulation. Rapidly released ATP triggers P2X1 -mediated ... [more ▼]

This study shows that, at low doses of collagen, glycoprotein VI activation leads to early protein kinase C- and MLC kinase-dependent platelet degranulation. Rapidly released ATP triggers P2X1 -mediated Ca2+ influx, activating ERK2, in turn amplifying platelet secretion by reinforcing the early MLC kinase phosphorylation. Hence, the P2X1-ERK2-MLC axis contributes to collagen-induced platelet activation by enhancing platelet degranulation. [less ▲]

Detailed reference viewed: 26 (5 ULiège)
Full Text
Peer Reviewed
See detailLe système d'échange de quotas d'émissions de gaz à effet de serre dans la Communauté européenne
Pâques, Michel ULiege

in Aménagement - Environnement (2003)

Detailed reference viewed: 46 (1 ULiège)
Full Text
See detailSkin immune dowregulators: from bench to bedside.
Pierard, Gérald ULiege; Franchimont, Claudine ULiege

in Current Topics in Pharmacology (2003), 7

New generations of topical skin immune downregulators (SIDRs) were recently introduced as an alternative to glucocorticoids for the topical treatment of some inflammatory dermatoses. Tacrolimus ... [more ▼]

New generations of topical skin immune downregulators (SIDRs) were recently introduced as an alternative to glucocorticoids for the topical treatment of some inflammatory dermatoses. Tacrolimus, pimecrolimus, sirolimus and dunaimycins inhibit the transcription of proinflammatory cytokine genes through binding to specific immunophilins. Taken together, SIDRs are able to inhibit a number of pro-inflammatory mediator systems and inflammatory cells with major importance for several cutaneous dermatitides. Therefore this group of compounds targeted dermatological diseases from the beginning of drug development. Several clinical trials have demonstrated the efficacy of tacrolimus and pimecrolimus in treating moderate to severe atopic dermatitis. Psoriasis, contact dermatitis and other dermatoses could also be indications for SIDRs. This review presents the cell biology changes and the mode of action of SIDRs. Their pharmacokinetics, clinical results and site effects are compared. [less ▲]

Detailed reference viewed: 39 (0 ULiège)
Full Text
Peer Reviewed
See detailCorrelation between Paired Responses Confirms the Existence of a Positive Ephaptic Feedback in Central Synapses
Koulchitsky, Stanislav ULiege; (Kulchitsky); Maximov, V. V. et al

in Doklady Biological Sciences (2003), 389(1), 102-104

Detailed reference viewed: 13 (1 ULiège)
Full Text
Peer Reviewed
See detailImproved rank-based dependence measures for categorical data
Vandenhende, François; Lambert, Philippe ULiege

in Statistics & Probability Letters (2003), 63

We extend rank-based dependence measures like Spearman's rho to categorical data so that the same ±1 limits are always reached under complete dependence. A goodness-of-fit procedure is derived for ... [more ▼]

We extend rank-based dependence measures like Spearman's rho to categorical data so that the same ±1 limits are always reached under complete dependence. A goodness-of-fit procedure is derived for dependence models using copulas. [less ▲]

Detailed reference viewed: 25 (2 ULiège)
Full Text
See detailObscure Sorrow Hill, The Caribbean Source of Wilson Harris's Fiction
Maes-Jelinek, Hena ULiege

in Caribbean Writer (The) (2003), 17

Detailed reference viewed: 23 (2 ULiège)
Full Text
See detailFinancement du terrorisme
Dantinne, Michaël ULiege; Seron, Vincent ULiege

in Revue de Droit Pénal et de Criminologie (2003), (6), 840-875

Detailed reference viewed: 176 (34 ULiège)
Full Text
Peer Reviewed
See detailMoins-values et plus-values d'urbanisme: La révision de l'article 70 du CWATUP
Pâques, Michel ULiege

in Revue du Notariat Belge (2003)

Detailed reference viewed: 61 (9 ULiège)
Full Text
Peer Reviewed
See detailDevelopment Of Real-Time Rt-Pcr Assay For Detection Of Prunus Necrotic Ringspot Virus In Fruit Trees
Marbot, Sophie; Vendrame, Marina; Huwaert, Astrid et al

in Plant Disease (2003), 87(11), 1344-1348

Detailed reference viewed: 20 (1 ULiège)
Full Text
Peer Reviewed
See detailEvaluation des risques biomécaniques pour la colonne lombaire au moyen d'un questionnaire
Somville, Pierre-René ULiege; Mairiaux, Philippe ULiege

in Médecine du Travail & Ergonomie= Arbeidsgezondheidszorg & Ergonomie (2003), 40(1), 5-17

Detailed reference viewed: 163 (21 ULiège)
Full Text
Peer Reviewed
See detailComparative clinical and electrometric assessments of the impact of surfactants on forearm skin.
Uhoda, Emmanuelle ULiege; Paye, Marc; Pierard, Gérald ULiege

in Exogenous Dermatology : Physical, Chemical, Biological (2003), 2

Surfactant-based skin care products can induce minimal to more severe alterations to human stratum corneum (SC). These changes can be conveniently assessed using electrometric devices. Four different ... [more ▼]

Surfactant-based skin care products can induce minimal to more severe alterations to human stratum corneum (SC). These changes can be conveniently assessed using electrometric devices. Four different surfactant-based solutions were applied on the forearms of 10 healthy volunteers following a soap chamber test method. The 2-day patch testing was followed by a 2-week follow-up. Clinical and instrumental assessments were performed at 7 time points. Data generated by the Corneometer® CM820, the DermaLab Moisture Module® and the Nova Dermal Phase Meter (DPM)® 9003 were compared. The significant differences between the product aggressiveness to the SC were similarly disclosed by the Corneometer® and the DermaLab Moisture Module®. The ranking of product aggressiveness given by the 3 devices 5 days after patch removal was similar to that given by the clinical assessment of erythema. A high level of correlation were found between the values yielded by the immediate and continuous mode assessments using the DermaLab Moisture Module with the Pin Probe, while the correlation was weaker with the Nova DPM®. This finding may be related to the fact that the Nova DPM is influenced by the accumulation of the transepidermal water loss in the continuous mode assessment while there is no significant occlusion effect of the DermaLab Moisture® Pin Probe that is more representative of the initial level of SC hydration. In conclusion, the Corneometer® and the DermaLab Moisture Module® respond similarly to changes in the SC content. This finding is different from some previous reports. [less ▲]

Detailed reference viewed: 74 (0 ULiège)
Full Text
Peer Reviewed
See detailComment j'explore ... une tache noire au cours de la grossesse. Une tache parfois difficile pour le clinicien.
Uhoda, I.; Pierard, Claudine ULiege; Arrese Estrada, Jorge ULiege et al

in Revue Médicale de Liège (2003), 58(12), 766-9

Cancers rarely coexist with pregnancy. Cutaneous melanoma, however, is one of the most frequently encountered neoplasms during pregnancy. Gestation may also be a period during which the aspect of some ... [more ▼]

Cancers rarely coexist with pregnancy. Cutaneous melanoma, however, is one of the most frequently encountered neoplasms during pregnancy. Gestation may also be a period during which the aspect of some melanocytic naevi can change eventhough the tumor remains benign. Distinction between a benign and a malignant lesion may then be a dilemma. Clinical morphometry, dermoscopy, skin surface biopsy, conventional histology and immunohistochemistry are valuable means that can be used to secure maximum diagnostic confidence. [less ▲]

Detailed reference viewed: 50 (1 ULiège)
Full Text
Peer Reviewed
See detailType I collagen triplet duplication mutation in lethal osteogenesis imperfecta shifts register of alpha chains throughout the helix and disrupts incorporation of mutant helices into fibrils and extracellular matrix.
Cabral, Wayne A; Mertts, Marianna V; Makareeva, Elena et al

in Journal of Biological Chemistry (2003), 278(12), 10006-12

The majority of collagen mutations causing osteogenesis imperfecta (OI) are glycine substitutions that disrupt formation of the triple helix. A rare type of collagen mutation consists of a duplication or ... [more ▼]

The majority of collagen mutations causing osteogenesis imperfecta (OI) are glycine substitutions that disrupt formation of the triple helix. A rare type of collagen mutation consists of a duplication or deletion of one or two Gly-X-Y triplets. These mutations shift the register of collagen chains with respect to each other in the helix but do not interrupt the triplet sequence, yet they have severe clinical consequences. We investigated the effect of shifting the register of the collagen helix by a single Gly-X-Y triplet on collagen assembly, stability, and incorporation into fibrils and matrix. These studies utilized a triplet duplication in COL1A1 exon 44 that occurred in the cDNA and gDNA of two siblings with lethal OI. The normal allele encodes three identical Gly-Ala-Hyp triplets at aa 868-876, whereas the mutant allele encodes four. The register shift delays helix formation, causing overmodification. Differential scanning calorimetry yielded a decrease in T(m) of 2 degrees C for helices with one mutant chain and a 6 degrees C decrease in helices with two mutant chains. An in vitro binary co-processing assay of N-proteinase cleavage demonstrated that procollagen with the triplet duplication has slower N-propeptide cleavage than in normal controls or procollagen with proalpha1(I) G832S, G898S, or G997S substitutions, showing that the register shift persists through the entire helix. The register shift disrupts incorporation of mutant collagen into fibrils and matrix. Proband fibrils formed inefficiently in vitro and contained only normal helices and helices with a single mutant chain. Helices with two mutant chains and a significant portion of helices with one mutant chain did not form fibrils. In matrix deposited by proband fibroblasts, mutant chains were abundant in the immaturely cross-linked fraction but constituted a minor fraction of maturely cross-linked chains. The profound effects of shifting the collagen triplet register on chain interactions in the helix and on fibril formation correlate with the severe clinical consequences. [less ▲]

Detailed reference viewed: 76 (2 ULiège)
Full Text
Peer Reviewed
See detailLes lymphomes
Jerusalem, Guy ULiege; Hustinx, Roland ULiege; Beguin, Yves ULiege et al

in Médecine Nucléaire : Imagerie Fonctionnelle et Métabolique (2003), 27(8), 401-410

Actuellement, on arrive à guérir 70-80% des patients atteints de maladie de Hodgkin et 50% des patients atteints de lymphome non-Hodgkinien de malignité intermédiaire ou élevée. Une approche systématique ... [more ▼]

Actuellement, on arrive à guérir 70-80% des patients atteints de maladie de Hodgkin et 50% des patients atteints de lymphome non-Hodgkinien de malignité intermédiaire ou élevée. Une approche systématique concernant le diagnostic, la classification de la maladie et la détermination des facteurs pronostiques permet de choisir la thérapeutique la plus appropriée. Les auteurs passent en revue les examens à réaliser au diagnostic et discutent de la place de la tomographie à émission de positons (TEP) dans cette indication. Ils évoquent ensuite le problème des masses résiduelles. La TEP est maintenant l'examen de choix pour établir le bilan de fin de traitement. Les auteurs discutent également du rôle potentiel de la TEP pour l'évaluation thérapeutique précoce et le suivi régulier des patients après traitement pour lymphome. Enfin, l'aspect particulier des lymphomes de l'enfant est abordé. [less ▲]

Detailed reference viewed: 54 (15 ULiège)
Full Text
Peer Reviewed
See detailBrain ethanol concentrations and ethanol discrimination in rats : effects of dose and time
Quertemont, Etienne ULiege; Green, Heather L.; Grant, Kathleen A.

in Psychopharmacology (2003), 168(3), 262-270

Rationale. In drug discrimination procedures, the substitution pattern for ethanol of various receptor ligands is dependent upon ethanol training dose, presumably reflecting functionally different ... [more ▼]

Rationale. In drug discrimination procedures, the substitution pattern for ethanol of various receptor ligands is dependent upon ethanol training dose, presumably reflecting functionally different concentrations of ethanol in the brain. The discriminative stimulus effects of ethanol are also time-dependent, although very few studies have investigated the time course of ethanol discriminations. Objectives. The present study investigated the relationship between brain ethanol concentrations (BrEC), as measured by intracranial microdialysis of the nucleus accumbens, and the time course of ethanol discriminative effects. Methods. Two groups of rats were trained to discriminate either 1.0 or 2.0 g/kg ethanol from water following a 30-min post-ethanol interval. Following training, the time course of the discriminative stimulus was assessed using a series of abbreviated testing trials at 20-min intervals for 5 h after the administration of various ethanol doses (0, 0.5, 1.0 and 2.0 g/kg). The rats were then fitted with microdialysis probes and the time course of BrECs were determined under conditions similar to the behavioral assessments. Results. BrECs were significantly above zero at 4 min post-gavage and attained peak concentrations of 16 mmol/l, 24 mmol/l and 42 mmol/l at 9 min, 16 min and 95 min after IG administration of 0.5, 1.0 and 2.0 g/kg ethanol, respectively. BrECs were similar in ethanol-naive and ethanol-trained rats, indicating a lack of pharmacokinetic tolerance under these discrimination procedures. The discriminative stimulus effects of ethanol were dose- and time-dependent, with a threshold concentration of approximately 12 mmol/l achieved at 5 min after 1.0 g/kg ethanol gavage in rats trained to discriminate 1.0 g/kg ethanol. Acute tolerance to the discriminative stimulus effects of ethanol was evident from BrECs 2-5 h post-ethanol gavage. Conclusions. Ethanol given intragastrically results in a rapid increase in BrEC, independent of ethanol exposure history. The discriminative stimulus effects of ethanol trained at 30 min post-gavage reflect a specific range of BrEC, and depend on the training dose. These data suggest that qualitatively different stimulus effects of ethanol reflect both different ranges of BrEC, as well as within dose acute tolerance to the discriminative stimulus effects. [less ▲]

Detailed reference viewed: 38 (3 ULiège)
Full Text
Peer Reviewed
See detailAndropause and psychopathology: minor symptoms rather than pathological ones.
Delhez, Marie; Hansenne, Michel ULiege; Legros, Jean-Jacques ULiege

in Psychoneuroendocrinology (2003), 28(7), 863-74

This study examined the psychological symptomatology of men diagnosed with andropause and the association between calculated free testosterone (T) and depressed mood, anxiety and quality of life. Subjects ... [more ▼]

This study examined the psychological symptomatology of men diagnosed with andropause and the association between calculated free testosterone (T) and depressed mood, anxiety and quality of life. Subjects were 153 men, aged 50-70 years, who participated in a screening of andropause. Total testosterone, FSH, LH and SHBG levels were measured. Depressed mood was assessed with the Carroll Rating Scale, anxiety with the "anxiety-insomnia" dimension of the General Health Questionnaire, and quality of life with the World Health Organisation Quality of Life questionnaire. The results showed that levels of free T decreased with age, whereas FSH and LH increased. Carroll Rating Scale scores were higher among hypogonadal subjects, but the mean score was low and not pathological. A negative correlation was observed between severity of depression as assessed by the Carroll Rating Scale and free T levels. However, subjects with a significant score on this scale did not exhibit different free T levels compared to subjects with a non-significant depressive score. Anxiety and quality of life did not differ between hypogonadal and eugonadal subjects. The present study therefore suggests that andropause is not characterised by specific psychological symptoms, but may be associated with "depressive symptoms" that are not considered as pathological. [less ▲]

Detailed reference viewed: 71 (3 ULiège)
Full Text
Peer Reviewed
See detailLa pustulose sous-cornee de Sneddon et Wilkinson.
Martalo, O.; Paquet, Philippe ULiege; Pierard, Gérald ULiege

in Revue Médicale de Liège (2003), 58(10), 628-30

The subcorneal pustular dermatosis of Sneddon and Wilkinson belongs to the heterogeneous group of neutrophilic dermatosis. This unique disorder is characterized by a superficial pustular eruption. The ... [more ▼]

The subcorneal pustular dermatosis of Sneddon and Wilkinson belongs to the heterogeneous group of neutrophilic dermatosis. This unique disorder is characterized by a superficial pustular eruption. The pustules are flaccid and aseptic. They develop predominantly on the trunk and in the groins, axillae and submammary areas. This disease is benign and chronic. However, it can be associated with some other conditions such as lymphoproliferative and myeloproliferative diseases. Dapsone is the treatment of choice to control the skin manifestations. [less ▲]

Detailed reference viewed: 123 (0 ULiège)
Full Text
See detailBiodiversity, molecular phylogeny, and trophodynamics of amphipod crustaceans in the Antarctic deep-sea
De Broyer, Claude; Dauby, Patrick ULiege; Nyssen, Fabienne et al

in Berichte zur Polar- und Meeresforschung (2003), 470

Detailed reference viewed: 45 (1 ULiège)
Full Text
See detailUne dermatite atopique sensible à un antifongique IBE.
Franchimont, Claudine ULiege; Pierard, Gérald ULiege

in Dermatologie Actualité (2003), 75

Detailed reference viewed: 31 (0 ULiège)
Full Text
Peer Reviewed
See detailOne-pot surfactant assisted synthesis of aluminosilicate macrochannels with tunable micro- or mesoporous wall structure
Léonard, Alexandre ULiege; Blin, J.-L.; Su, B.-L.

in Chemical Communications (2003), 9(20), 2568-2569

A one-step surfactant assisted synthesis pathway was developed leading to novel hierarchical macro-meso- (or micro-)porous aluminosilicates made of an assembly of macrochannels with openings between 0.5 ... [more ▼]

A one-step surfactant assisted synthesis pathway was developed leading to novel hierarchical macro-meso- (or micro-)porous aluminosilicates made of an assembly of macrochannels with openings between 0.5 and 2.0 μm and wormhole-like amorphous walls with tunable pore sizes. [less ▲]

Detailed reference viewed: 13 (1 ULiège)
Full Text
Peer Reviewed
See detailCTD measurements, with emphasis on Elephant Island surroundings
Dauby, Patrick ULiege

in Berichte zur Polar- und Meeresforschung (2003), 470

Detailed reference viewed: 17 (1 ULiège)
Full Text
Peer Reviewed
See detailAnalysis Of Accessible Surface Of Residues In Proteins
Lins, Laurence ULiege; Thomas, Annick ULiege; Brasseur, Robert ULiege

in Protein Science : A Publication of the Protein Society (2003), 12(7),

Detailed reference viewed: 8 (0 ULiège)
Full Text
Peer Reviewed
See detailSynopsis des dermatomycoses invasives chez l'immunodéprimé.
Quatresooz, Pascale ULiege; Arrese Estrada, Jorge ULiege; Pierard, Gérald ULiege

in Revue Médicale de Liège (2003), 58(11), 690-4

The immune system plays a prominent role in the defense against a wide variety of pathogen fungi. Thus, the immunocompromised patient becomes a potential victim of mycoses originating from the skin. These ... [more ▼]

The immune system plays a prominent role in the defense against a wide variety of pathogen fungi. Thus, the immunocompromised patient becomes a potential victim of mycoses originating from the skin. These mycoses may become invasive and a fatal issue is possible. In other circumstances, the inoculation site is pulmonary or digestive, and the cutaneous lesions represent secondary localizations. [less ▲]

Detailed reference viewed: 172 (4 ULiège)
Full Text
Peer Reviewed
See detailCell Handling, Membrane-Binding Properties, And Membrane-Penetration Modeling Approaches Of Pivampicillin And Phthalimidomethylampicillin, Two Basic Esters Of Ampicillin, In Comparison With Chloroquine And Azithromycin
Chanteux, H.; Paternotte, I.; Mingeot-Leclercq, Mp. et al

in Pharmaceutical Research (2003), 20(4), 624-31

PURPOSE: The purpose of this work was to examine and understand the cellular pharmacokinetics of two basic esters of ampicillin, pivaloyloxymethyl (PIVA) and phthalimidomethyl (PIMA), in comparison with ... [more ▼]

PURPOSE: The purpose of this work was to examine and understand the cellular pharmacokinetics of two basic esters of ampicillin, pivaloyloxymethyl (PIVA) and phthalimidomethyl (PIMA), in comparison with lysosomotropic drugs (chloroquine, azithromycin). METHODS: Cell culture studies (J774 macrophages) were undertaken to study uptake and release kinetics and to assess the influence of concentration, pH, proton ionophore (monensin), and MRP and P-gp inhibitors (probenecid, gemfibrozil, cyclosporin A, GF 120918). Equilibrium dialysis with liposomes were performed to directly asses the extent of drug binding to bilayers. Conformational analysis modeling of the drug penetration in bilayers was conducted to rationalize the experimental observations. RESULTS: PIVA and PIMA showed properties in almost complete contrast with those of chloroquine and azithromycin, i.e., fast apparent accumulation and fast release at 4 degrees C as well as at 37 degrees C, saturation of uptake (apparent Kd 40 microM), no influence of monensin, MRP, or P-gp inhibitors; tight binding to liposomes (Kd approx. 40 microM); and sharp increase in calculated free energy when forced in the hydrophobic domain. CONCLUSIONS: Although they are weak organic bases, PIVA and PIMA show none of the properties of lysosomotropic agents. We hypothesize that they remain locked onto the pericellular membrane and may never penetrate cells as such in significant amounts. [less ▲]

Detailed reference viewed: 6 (0 ULiège)
Full Text
Peer Reviewed
See detailCellular Uptake Of Antennapedia Penetratin Peptides Is A Two-Step Process In Which Phase Transfer Precedes A Tryptophan-Dependent Translocation
Dom, G.; Shaw-Jackson, C.; Matis, C. et al

in Nucleic Acids Research (2003), 31(2), 556-61

Several homeodomains and homeodomain-containing proteins enter live cells through a receptor- and energy-independent mechanism. Translocation through biological membranes is conferred by the third alpha ... [more ▼]

Several homeodomains and homeodomain-containing proteins enter live cells through a receptor- and energy-independent mechanism. Translocation through biological membranes is conferred by the third alpha-helix of the homeodomain, also known as Penetratin. Biophysical studies demonstrate that entry of Penetratin into cells requires its binding to surface lipids but that binding and translocation are differentially affected by modifications of some physico-chemical properties of the peptide, like helical amphipathicity or net charge. This suggests that the plasma membrane lipid composition affects the internalization of Penetratin and that internalization requires both lipid binding and other specific properties. Using a phase transfer assay, it is shown that negatively charged lipids promote the transfer of Penetratin from a hydrophilic into a hydrophobic environment, probably through charge neutralization. Accordingly, transfer into a hydrophobic milieu can also be obtained in the absence of negatively charged lipids, by the addition of DNA oligonucleotides. Strikingly, phase transfer by charge neutralization was also observed with a variant peptide of same charge and hydrophobicity in which the tryptophan at position 6 was replaced by a phenylalanine. However, Penetratin, but not its mutant version, is internalized by live cells. This underscores that charge neutralization and phase transfer represent only a first step in the internalization process and that further crossing of a biological membrane necessitates the critical tryptophan residue at position 6. [less ▲]

Detailed reference viewed: 25 (1 ULiège)
Full Text
Peer Reviewed
See detailCombined enzymatic hydrolysis and HPAEC method for simultaneous analysis of galacturonic acid and neutral sugars of pectin.
Garna, H.; Mabon, N.; Wathelet, Bernard ULiege et al

in Communications in Agricultural and Applied Biological Sciences (2003), 68(2 Pt A), 297-300

Detailed reference viewed: 72 (4 ULiège)
Full Text
Peer Reviewed
See detailLe catastérisme chez Homère. Le cas d'Orion
Renaud, Jean-Michel ULiege

in Gaia. Revue interdisciplinaire sur la Grèce archaïque (2003), 7

Detailed reference viewed: 75 (2 ULiège)
Full Text
Peer Reviewed
See detailDiurnal Centroid Of Ecosystem Energy And Carbon Fluxes At Fluxnet Sites
Wilson, Kb.; Baldocchi, D.; Falge, E. et al

in Journal of Geophysical Research. Atmospheres (2003), 108(D21),

Detailed reference viewed: 34 (5 ULiège)
Full Text
Peer Reviewed
See detailEnfin "Tubambe" devoile son identite! Hadraphe ethiopica (Bethune-Baker) (Limacodidae), une chenille comestible des forets claires zambeziennes.
Malaisse, François ULiege; Demesmaecker, Anne; Matera, Joseph et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2003), 7(2), 67-77

La consommation humaine de chenilles de Limacodidae avait été signalée en Afrique centro-australe. L’une de ces espèces, Hadraphe ethiopica, a été déterminée. Des données relatives à sa biologie ont été ... [more ▼]

La consommation humaine de chenilles de Limacodidae avait été signalée en Afrique centro-australe. L’une de ces espèces, Hadraphe ethiopica, a été déterminée. Des données relatives à sa biologie ont été rassemblées. Des analyses d’échantillons séchés ont permis de préciser leur composition chimique et leur valeur nutritionnelle, notamment sur le plan des acides aminés et des acides gras. [less ▲]

Detailed reference viewed: 64 (9 ULiège)
Full Text
See detailPour améliorer l'apprentissage d'une langue moderne à l'école primaire
Blondin, Christiane ULiege; Straeten, M.

in Point sur la Recherche en Education (Le) (2003), 27

Detailed reference viewed: 69 (5 ULiège)
Full Text
Peer Reviewed
See detailDust-acoustic modes in plasmas with dust distributions and charge fluctuations
Verheest, F.; Jacobs, G.; Cattaert, Tom ULiege

in New Journal of Physics (2003), 5

Charge fluctuations in dusty plasmas are discussed starting from charge, mass, momentum and current equations for the combined dusty plasma. This allows a generic description of low-frequency waves in ... [more ▼]

Charge fluctuations in dusty plasmas are discussed starting from charge, mass, momentum and current equations for the combined dusty plasma. This allows a generic description of low-frequency waves in plasmas with dust distributions, and leads to the damping and other modifications of the dust-acoustic and related modes, like generalized dust-Coulomb modes. [less ▲]

Detailed reference viewed: 28 (2 ULiège)
Full Text
Peer Reviewed
See detailModelling eutrophication in mesotidal and macrotidal estuaries. The role of intertidal seaweeds.
Alvera Azcarate, Aïda ULiege; Ferreira, Joao; Nunes, Joao

in Estuarine Coastal & Shelf Science (2003), 57

The role of intertidal seaweeds in the primary production of mesotidal and macrotidal estuaries has been examined by means of a model, applied to the Tagus Estuary (Portugal). Special attention was paid ... [more ▼]

The role of intertidal seaweeds in the primary production of mesotidal and macrotidal estuaries has been examined by means of a model, applied to the Tagus Estuary (Portugal). Special attention was paid to the description of the underwater light climate in intertidal areas, and to the importance of the formation of tidal pools. Two approaches were compared for the simulation of suspended particulate matter (SPM) in the pool areas, using three algal species. The use of an erosion–deposition approach to simulate the distribution of SPM in tidal pools gives an increase in net primary productivity per unit area of between 130 and 1300%, when compared to the more conventional approach where the suspended matter in the overlying water in intertidal areas is considered identical to that in the channels. The upscaled erosion–deposition model was applied to tidal pool areas and combined with the more conventional model for other intertidal areas. Results show that annual carbon fixation by intertidal seaweeds in the estuary exceeds 13,500 t C yr−1, and accounts for 21% of the total carbon fixed by all primary producers. The corresponding nitrogen removal by seaweeds corresponds to the annual nutrient loading of a population of 490,000 inhabitants. [less ▲]

Detailed reference viewed: 59 (3 ULiège)
Full Text
Peer Reviewed
See detailEvaluation of thyroid function in obese dogs and in dogs undergoing a weight loss protocol
Daminet, Sylvie; Jeusette, Isabelle; Duchateau, L. et al

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (2003), 50(4), 213-218

Obesity and weight loss have been shown to alter thyroid hormone homeostasis in humans. In dogs, obesity is the most common nutritional problem encountered and weight loss is the cornerstone of its ... [more ▼]

Obesity and weight loss have been shown to alter thyroid hormone homeostasis in humans. In dogs, obesity is the most common nutritional problem encountered and weight loss is the cornerstone of its treatment. Therefore, it is important to clarify how obesity and weight loss can affect thyroid function test results in that species. The objectives of this study were to compare thyroid function in obese dogs and in lean dogs and to explore the effects of caloric restriction and weight loss on thyroid hormone serum concentrations in obese dogs. In the first experiment, 12 healthy lean beagles and 12 obese beagles were compared. Thyroid function was evaluated by measuring serum concentrations of total thyroxine (TT4), free thyroxine (FT4), total triiodothyronine (TT3), thyrotropin (TSH), and reverse triiodothyronine (rT3) as well as a TSH stimulation test using 75 mu g IV of recombinant human TSH. In the second experiment, eight obese beagles were fed an energy-restricted diet [average 63% maintenance energy requirement (MER)] until optimal weight was obtained. Blood samples for determination of TT4, FT4, TT3, TSH and rT3, were taken at the start and then weekly during weight loss. Only TT3 and TT4 serum concentrations were significantly higher in obese dogs as compared to lean dogs. In the second experiment, weight loss resulted in a significant decrease in TT3 and TSH serum concentrations. Thus obesity and energy restriction significantly alter thyroid homeostasis in dogs, but the observed changes are unlikely to affect interpretation of thyroid function test results in clinics. [less ▲]

Detailed reference viewed: 59 (6 ULiège)
Full Text
Peer Reviewed
See detailHigh-Performance Liquid Chromatography Analyses Of Pyoverdin Siderophores Differentiate Among Phytopathogenic Fluorescent Pseudomonas Species
Bultreys, Alain; Gheysen, Isabelle; Wathelet, Bernard ULiege et al

in Applied and Environmental Microbiology (2003), 69(2),

Detailed reference viewed: 27 (0 ULiège)
Full Text
Peer Reviewed
See detailCreolization in Robert Antoni's Blessed Is the Fruit: A Linguistic Analysis
Ledent, Bénédicte ULiege

in Matatu : Journal for African Culture and Society (2003), 27-28

Detailed reference viewed: 73 (24 ULiège)
Full Text
Peer Reviewed
See detailGas chromatography-olfactometry analysis of the volatile compounds of two commercial Irish beef meats
Machiels, D.; van Ruth, S. M.; Posthumus, M. A. et al

in Talanta (2003), 60(4), 755-764

The volatile flavour compounds of two commercial Irish beef meats (labelled as conventional and organic) were evaluated by gas chromatography-olfactometry and were identified by gas chromatography-mass ... [more ▼]

The volatile flavour compounds of two commercial Irish beef meats (labelled as conventional and organic) were evaluated by gas chromatography-olfactometry and were identified by gas chromatography-mass spectrometry. The volatile compounds were isolated in a model mouth system. Gas chromatography-olfactometry was performed by a group of eight assessors using the detection frequency methodology. The odours of the detected compounds were described as well. Eighty-one volatile compounds were identified, 11 compounds of which possessed odour activity in the first beef sample and 14 of which in the second meat sample. Ten volatile flavour compounds were common to both: methanethiol, dimethyl sulphide, 2-butanone, ethyl acetate, 2- and 3-methylbutanal, an unknown compound, 2-octanone, decanal and benzothiazole. Two unknown compounds were only detected in the first sample while 2,3-pentanedione, 4-methyl-3-penten-2-one, 2-heptanone, dimethyl trisulphide and nonanal were only perceived in the second beef. Significant differences in terms of detection frequency, odour characteristics and in nature of the volatile flavour compounds were emphasised between the two samples. (C) 2003 Elsevier Science B.V. All rights reserved. [less ▲]

Detailed reference viewed: 58 (0 ULiège)
Full Text
Peer Reviewed
See detailEmile Adan en de introductie van reisinstructies voor de Belgische wetenschappelijke exploratie in Midden-Afrika.
Vandersmissen, Jan ULiege

in Archives et Bibliothèques de Belgique = Archief en Bibliotheekwezen in Belgie (2003), 74(1-4), 205-217

Detailed reference viewed: 25 (0 ULiège)
Full Text
Peer Reviewed
See detailLa géographie appliquée à l’université de Liège
Binard, Marc ULiege; Devillet, Guénaël ULiege; Erpicum, Michel ULiege

in Bulletin de la Société Géographique de Liège (2003), 43

Historic of the applied geography within the various units of the Geographic Department of the University of Liège (Belgium)

Detailed reference viewed: 89 (25 ULiège)
Full Text
Peer Reviewed
See detailPatterns Of Bryophyte Diversity And Rarity At A Regional Scale
Vanderpoorten, Alain ULiege; Engels, Patrick ULiege

in Biodiversity & Conservation (2003), 12(3),

Detailed reference viewed: 20 (0 ULiège)
Full Text
Peer Reviewed
See detailAnalysis of soil and crop properties for precision agriculture for winter wheat
Vrindts, Els; Reyniers, Marieke; Darius, Paul et al

in Biosystems Engineering (2003), 85(2), 141-152

In a precision farming research project financed by the Belgian Ministry of Small Trade and Agriculture, the methods of precision agriculture are tested on grain fields with a view of implementation of ... [more ▼]

In a precision farming research project financed by the Belgian Ministry of Small Trade and Agriculture, the methods of precision agriculture are tested on grain fields with a view of implementation of precision agriculture methods in Belgian field agriculture. The project encompasses methods for automatic information gathering on soil and crop and analysis of this data for management of within-field variability. Automatic information capturing is combined with traditional data sources of soil sample analysis and crop observations. The measurements and part of the results on one particular field in Sauvenière are presented here. Five nitrogen management strategies were compared, but the resulting differences in nitrogen dose were small and did not lead to significantly different yield results. The yield results were correlated to topography-related variations in soil texture and chemical components and to crop reflectance measurements in May. [less ▲]

Detailed reference viewed: 122 (21 ULiège)
Full Text
Peer Reviewed
See detailThe emotional content of material and reality monitoring function in subjects predisposed towards hallucinations
Laroi, Frank ULiege; Marczewski, P.; Van der Linden, Martial ULiege et al

in Brain and Cognition (2003), 51

Detailed reference viewed: 26 (0 ULiège)
Full Text
Peer Reviewed
See detailThe family systems approach to treating families of persons with brain injury: a potential collaboration between family therapist and brain injury professional
Laroi, Frank ULiege

in Brain Injury (2003), 17

Although brain injury may have a great impact on the family as a whole, family reactions are not adequately addressed in rehabilitative programmes. When they are, treatment tends to be approached from a ... [more ▼]

Although brain injury may have a great impact on the family as a whole, family reactions are not adequately addressed in rehabilitative programmes. When they are, treatment tends to be approached from a family education and support perspective and not from a family therapy perspective. The aim of the following paper is to illustrate the important role that a family systems approach can play in treating families of individuals with brain injury. In particular, clinical examples taken from the literature will be presented that illustrate how family roles can be modified as a consequence of a brain injury, and the importance of re-establishing or re-distributing these roles. It will be argued that an intimate collaboration between family therapist and brain injury professional is essential, and that the ideal professional make-up of clinicians working with families of persons with brain injury are those well-versed in both brain injury rehabilitation and family therapy. [less ▲]

Detailed reference viewed: 50 (1 ULiège)