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See detailFibres alimentaires chez le chien III. Effets sur les structures intestinales et les fermentations. Applications dans le traitement de certains dysfonctionnements intestinaux
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141

Dietary fibres can modify the intestinal structure in dogs and other animal species. The main changes concern not only the morphology of the gastrointestinal tract but also the ultrastructures ... [more ▼]

Dietary fibres can modify the intestinal structure in dogs and other animal species. The main changes concern not only the morphology of the gastrointestinal tract but also the ultrastructures. Furthermore, soluble and partly-soluble fibres are fermented in the large bowel; the fermentation products have different metabolic effects. The physical and chemical properties of fibres can be used for the dietary therapy of some intestinal pathologies [less ▲]

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See detailIntensivemedizinische Probleme nach kardiochirurgischen Eingriffen in der Neugeborenenperiode
Hörnchen, H.; Dreuw, M.; Merz, U. et al

in Monatsschrift fur Kinderheilkunde (1997), 145

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See detailDeux POHLIA méconnus d'Alsace: P.lutescens (Limpr.) Lindb. et P. lescuriana (Sull.) Andrews
Vanderpoorten, Alain ULg

in Bulletin de la Société d'Histoire Naturelle de Colmar (1997), 63

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See detailAcetaldehyde-induced changes in the monoamine and amino acid extracellular microdialysate content of the nucleus accumbens
Ward, Roberta J.; Colantuoni, Carlo; Dahchour, Abdelkhader et al

in Neuropharmacology (1997), 36(2), 225-232

The effect of an acute intraperitoneal (i.p.) injection of acetaldehyde, 20 mglkg or 100mg/kg, on the microdialysate content of both amino acids and monoamine was studied in the nucleus accumbens (NA) by ... [more ▼]

The effect of an acute intraperitoneal (i.p.) injection of acetaldehyde, 20 mglkg or 100mg/kg, on the microdialysate content of both amino acids and monoamine was studied in the nucleus accumbens (NA) by a microdialysis technique. Acetaldehyde (ACH) which was detectable at levels of 50-130 µmol/g brain tissue 10 min after injection, evoked a significantd ecrease in the extracellular microdialysis dopamine content, which was sustained for the period of the study, i.e. 120 min. Homovanillicacid, HVA, decreased significantly when the lower dose of ACH was administered while dihydrophenylaceticacid, DOPAC, showed no significant change with either dose of ACH during the period of the study. Serotonin levels decreased significantly after both doses of acetaldehyde, with significant increases of its major metabolite, hydroxyindolacetic acid, 5-HIAA, with the higher acetaldehyde dose. Taurine increased significantly, only during the first twenty minutes, after both doses of acetaldehyde, although neither of the excitatory amino acids assayed, glutamate and aspartate, nor the inhibitoryamino acid, GABA, showed any significant changes. Acetaldehyde clearly evokes significant perturbation in the monoamine content of the NA, such changes being the converse to those reported for monoamine after ethanol administration, which might indicate a negative reinforcement effect. [less ▲]

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See detailTechnical validation of a face mask adapted for dry powder inhalation in the equine species
Duvivier, Dominique Hannia; Votion, Dominique ULg; Vandenput, Sandrina ULg et al

in Equine Veterinary Journal (1997), 29(6), 471-476

Development of dry powder inhalation (DPI) for horses requires the use of an adapted face mask. In experiment I, 4 masks (A, B, C and D) were tested and factors influencing the delivery of the dry powder ... [more ▼]

Development of dry powder inhalation (DPI) for horses requires the use of an adapted face mask. In experiment I, 4 masks (A, B, C and D) were tested and factors influencing the delivery of the dry powder were determined. Mask A was one which is commercially available for metered-dose inhalation. Mask B had the same shape as Mask A but an airtight rubber seal was added for the connection between the mask and horse's head. Mask C was a prototype adapted for DPI with connection for the DPI device between the nostrils, airtight expiratory valves in front of each nostril and airtight rubber seal to attach the mask on the horse's head. Mask D was the same as Mask C but the airtight expiratory valve was situated in front of one nostril and the connection for the DPI device was placed in front of the other nostril. Inhalet emptying and peak inspiratory pressure were measured on 5 healthy horses with each face mask. Both Masks A and B gave a low rate of inhalet emptying. Inspiratory pressures created in Masks C and D were negative enough to ensure inhalet emptying rates of mean +/- s.d. 98.28 +/- 1.79% and 100% respectively. In experiment 2, the face masks giving the greatest inhalet emptying were used to test the therapeutic efficacy of ipratropium bromide DPI. This was tested on 6 horses suffering from acute exacerbation of chronic obstructive pulmonary disease (COPD). At a dose of 200 micrograms/100 kg bwt, ipratropium administered with Mask D improved significantly pulmonary function measurements compared to baseline values and placebo inhalation. With Mask C, a double dose of ipratropium (400 micrograms/100 kg bwt) was necessary to improve these parameters compared to baseline values. This indicated the importance of locating the DPI device in front of one nostril. It was concluded that inhalet emptying is correlated to inspiratory pressures measured in the face masks. Secondly, these pressures are in turn dependent on the air-tightness of the mask, i.e. air-tightness of the expiratory valve and close connection between the horse's head and the mask. Thirdly, position of the DPI device in front of a nostril allows bronchodilation at a dose half that required when the device is placed between the nostrils. Finally DPI using Mask D (EquiPoudre) is a rapid, effective and well tolerated inhalation treatment for COPD horses. [less ▲]

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See detailObserved trends in total vertical column abundances of atmospheric gases from IR solar spectra recorded at the Jungfraujoch
Mahieu, Emmanuel ULg; Zander, Rodolphe ULg; Delbouille, Luc et al

in Journal of Atmospheric Chemistry (1997), 28(1-3), 227-243

Since 1984, about 15 000 high quality infrared solar spectra have been recorded with state-of-the-art grating and Fourier transform spectrometers at the International Scientific Station of the ... [more ▼]

Since 1984, about 15 000 high quality infrared solar spectra have been recorded with state-of-the-art grating and Fourier transform spectrometers at the International Scientific Station of the Jungfraujoch, Switzerland. Nonlinear least squares spectral curve fitting of selected microwindows containing isolated and well characterized lines of 20 telluric gases have allowed to retrieve their total vertical column abundances above the station, leading to observational data bases essential to derive long- and short-term changes experienced by these species during the last 12 years. In this paper, we focus on atmospheric gases of particular interest within the context of the EUROTRACTOR (Tropospheric Ozone Research) project; secular evolution as well as seasonal cycles of the minor constituents CH4, CO and of the trace gases C2H6, OCS, C2H2, HCN and H2CO are reported and discussed. The long-lived N2O is included as a tracer of the dynamic activity of the atmosphere. [less ▲]

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See detailUne route mérovingienne en Hautes-Fagnes (La Via Mansuerisca ?). Derniers résultats scientifiques.
Streel, Maurice ULg

in Bulletin de l"Académie Royale de Belgique, Classe Sciences 6e série (1997), VIII(7-12), 367-376

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See detailAntibodies against vaccinia virus do not neutralize extracellular enveloped virus but prevent virus release from infected cells and comet formation
Vanderplasschen, Alain ULg; Hollinshead, M.; Smith, G. L.

in Journal of General Virology (The) (1997), 78(Pt 8), 2041-2048

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See detailLarga existencia y breve desaparición: el adiós de una revista cultural.
Vanden Berghe, Kristine ULg

in América. Cahiers du CRICCAL (1997), 18(II), 587-600

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See detailLes rideaux de Magritte
Steinmetz, Rudy ULg

in Degrés : Revue de Synthèses à Orientation Sémiologique (1997)

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See detailFibres alimentaires chez le chien II. Effets sur la vidange gastrique et le transit gastro-intestinal
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141

The aim of this second review is to summarize data on the duration of gastric emptying and on the transit time in the gastrointestinal tract of healthy dogs. An overview of the investigation techniques is ... [more ▼]

The aim of this second review is to summarize data on the duration of gastric emptying and on the transit time in the gastrointestinal tract of healthy dogs. An overview of the investigation techniques is also given. The incorporation of fibres in the diet is one of many other factors which influence the mechanisms of emptying in the gastrointestinal tract. The effect of dietary fibres is also discussed in other monogastric species [less ▲]

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See detailChanges in the Distribution Pattern of Galectin-1 and Galectin-3 in Human Placenta Correlates with the Differentiation Pathways of Trophoblasts
Maquoi, Erik ULg; van den Brule, F. A.; Castronovo, Vincenzo ULg et al

in Placenta (1997), 18(5-6, Jul-Aug), 433-9

Human placentation is a complex biological phenomenon that results from precisely regulated interactions between cells and the extracellular matrix. Galectin- 1 and galectin-3 belong to a newly defined ... [more ▼]

Human placentation is a complex biological phenomenon that results from precisely regulated interactions between cells and the extracellular matrix. Galectin- 1 and galectin-3 belong to a newly defined family of galactose-binding lectins that can bind several glycoconjugates such as the basement membrane glycoprotein laminin, and are involved in many biological events including cell adhesion. In this study, the expression of these two galectins in first and third trimester normal human placenta was examined using single and double immunohistochemical staining and specific antibodies for galectins and cytokeratins. Galectin-3 was detected in all trophoblastic lineages including villous cytotrophoblasts and extravillous trophoblasts (trophoblastic cell columns, infiltrating trophoblasts, endovascular trophoblasts and placental bed giant cells). On the contrary, galectin-1 distribution was restricted to endometrium. A reduction of galectin-3 expression was observed from the villous trophoblasts to the trophoblastic cell columns. This pattern correlated with the switch from a proliferative to a migratory phenotype. Galectin-1 and galectin-3 were both detected in maternal decidual cells. Our data demonstrate a specific pattern of galectin-1 and galectin-3 expression in trophoblastic tissue, and suggest these lectins could contribute to cell-cell and cell matrix interactions of trophoblast during placentation. [less ▲]

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See detailProgramme EsQUIsE. Acquisition et interprétation de croquis d'architecture
Leclercq, Pierre ULg

in La lettre de l'IA (1997), 123

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See detailLa controverse a propos de la decouverte de l'insuline. L'histoire vue sous l'angle de la philatelie.
Scheen, André ULg

in Revue Médicale de Liège (1997), 52(12), 756-9

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See detailImprovement of inland navigation in developping countries: the training center of Palembang (Sumatra, Indonesia), an example of transfer of technology through education
Marchal, Jean ULg

in Bulletin des Séances de l’Académie Royale des Sciences d’Outre-Mer = Mededelingen der Zittingen van de Koninklijke Academie voor Overzeese Wetenschappen (1997), Nouvelle Série 42(4)(1er trimestre), 10

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See detailThe meaning of formal: from weak to strong formal methods
Wolper, Pierre ULg

in International Journal on Software Tools for Technology Transfer (1997), 1(1-2), 6--8

This short note reflects on what makes formal methods "formal". It concludes that there are weak and strong ways of being formal, the latter being linked to the formality of the method being exploitable ... [more ▼]

This short note reflects on what makes formal methods "formal". It concludes that there are weak and strong ways of being formal, the latter being linked to the formality of the method being exploitable, and exploited, in software tools. [less ▲]

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See detailThe early stages of photosystem II assembly monitored by measurements of fluorescence lifetime, fluorescence induction and isoelectric focusing of chlorophyll-proteins in barley etiochloroplasts
MysliwaKurdziel, B.; Barthelemy, X.; Strzalka, K. et al

in Plant & Cell Physiology (1997), 38(11), 1187-1196

The relationship between functional and structural aspects of PSII formation during greening of etiolated barley leaves has been investigated using fluorescence life-time measurements, fluorescence ... [more ▼]

The relationship between functional and structural aspects of PSII formation during greening of etiolated barley leaves has been investigated using fluorescence life-time measurements, fluorescence kinetics analysis and analysis of chlorophyll-protein complexes by IEF-PAGE, Two phases of different character could be distinguished in the course of the greening process in dark-grown plants, An early phase covering the first 3-4 h after the onset of illumination and a late phase covering the subsequent greening, During the first phase the formation of PSII reaction centers and their minor antenna components was observed as manifested by the IEF-PAGE polypeptide pattern, This was accompanied by shortening of the slow and middle components of the fluorescence lifetime, as well as by the rapid drop in the amplitude of the slow component, A room temperature emission band at 676 nm was associated with uncoupled chlorophyll and with the slow fluorescence lifetime component during the first hours of greening. During the late greening phase peripheral light-harvesting complexes of PSII were formed concomitantly to an increase in lifetime and amplitude of the fast component and to a further decrease in the lifetime of the middle component, The gradual increase in PSII complexity during both phases of greening was also manifested by changes in proportion and kinetic properties of PSIIalpha and PSIIbeta units. Similar changes in fluorescence lifetime components as in the late greening of dark-grown plants were also observed in intermittent-light plants during continuous greening associated with the development of PSII antenna. The relationships between fluorescence lifetime characteristics and development of PSII are discussed in terms of a stepwise mechanism invoving a first step of Chl integration into small size PSII units followed by progressive increase of antenna size. [less ▲]

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See detailPharma-clinics. Le medicament du mois. Le Legalon (silymarine).
Luyckx, Françoise ULg; Scheen, André ULg

in Revue Médicale de Liège (1997), 52(12), 792-6

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See detailFibres alimentaires chez le chien : VII. Intérêt dans le traitement diététique de l'animal obèse
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with ... [more ▼]

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with particular emphasis on the incorporation of large quantities of dietary fibres in low-energy specific purpose food. At present time, no conclusions can be drawn from published studies [less ▲]

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See detailDiagnostic de l'ostéoporose
Devogelaer, JP; Reginster, Jean-Yves ULg; Raeman, F et al

in Medipractice (1997), 21

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See detailExpression of c-ets-1 mRNA is associated with an invasive, EMT-derived phenotype in breast carcinoma cell lines.
Gilles, Christine ULg; Polette, M.; Birembaut, P. et al

in Clinical & Experimental Metastasis (1997), 15(5), 519-26

We have previously observed in vitro that some stromal proteinases (MMP-2, MT1-MMP) were expressed or activated by invasive carcinoma cell lines exhibiting mesenchymal features, presumably acquired ... [more ▼]

We have previously observed in vitro that some stromal proteinases (MMP-2, MT1-MMP) were expressed or activated by invasive carcinoma cell lines exhibiting mesenchymal features, presumably acquired through an epithelial to mesenchymal transition (EMT). To examine the potential contribution of c-ets-1 to this phenotype, we have compared here the expression of c-ets-1 with invasiveness in vitro and expression of vimentin, E-cadherin, uPA, MMP-1 and MMP-3 in a panel of human breast cancer cell lines. Our results clearly demonstrate an association between c-ets-1 expression and the invasive, EMT-derived phenotype, which is typified by the expression of vimentin and the lack of E-cadherin. While absent from the two non-invasive, vimentin-negative cell lines, c-ets-1 was abundantly expressed in all the four vimentin-positive lines. However, we could not find a clear quantitative or qualitative relationship between the expression of c-ets-1 and the three proteinases known to be regulated by c-ets-1, except that when they were expressed, it was only in the invasive c-ets-1-positive lines. UPA mRNAs were found in three of the four vimentin-positive lines, MMP-1 in two of the four, and MMP-3 could not be detected in any of the cell lines. Intriguingly, MDA-MB-435 cells, which exhibit the highest metastatic potential of these cell lines in nude mice, expressed vimentin and c-ets-1, but lacked expression of these three proteinases, at least under the culture conditions employed. Taken together, our results show that c-ets-1 expression is associated with an invasive, EMT-derived phenotype in breast cancer cells, although it is apparently not sufficient to ensure the expression of uPA, MMP-1 or MMP-3, in the vimentin-positive cells. Such proteases regulation is undoubtedly qualified by the cellular context. This study therefore advances our understanding of the molecular regulation of invasiveness in EMT-associated carcinoma progression, and suggests that c-ets-1 may contribute to the invasive phenotype in carcinoma cells. [less ▲]

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See detailRadiative Lifetimes for the 4p Excited States of Phosphorus and the Oscillator Strengths of Solar Lines
Berzinsh, U.; Svanberg, S.; Biémont, Emile ULg

in Astronomy and Astrophysics (1997), 326

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See detailThéorie de l'approche hydrogéologique des écoulements et transports en zone partiellement saturée
Dassargues, Alain ULg

in Annales de la Société Géologique de Belgique (1997), 119(1), 71-89

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See detailLes pesticides: effets endocriniens et cancérogènes chez l'Homme
Charlier, Corinne ULg; Plomteux, Guy ULg

in Toxicorama (1997), IX

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See detailRecherche d'information et pragmatisme : II. Utilité sociale de la confirmation d'hypothèses
Dardenne, Benoît ULg; Leyens, J.; Yzerbyt, V. Y.

in Année Psychologique (L') (1997), 97

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See detailBovine Herpesvirus 1-Induced Apoptosis Occurs At The G0/G1 Phase Of The Cell Cycle
Hanon, Emilien ULg; Hoornaert, S.; Dequiedt, Franck ULg et al

in Virology (1997), 232(2), 351-358

We have previously shown that bovine herpesvirus 1 (BHV-1), even when inactivated, induces apoptotic cell death in mitogen-stimulated bovine peripheral blood mononuclear cells (PBMCs) (Hanon et al., 1996 ... [more ▼]

We have previously shown that bovine herpesvirus 1 (BHV-1), even when inactivated, induces apoptotic cell death in mitogen-stimulated bovine peripheral blood mononuclear cells (PBMCs) (Hanon et al., 1996, J. Virol. 70, 4116-4120). In order to gain insight into this process, we have investigated the cell cycle phase at which BHV-1 induces apoptosis in PBMCs. Our results show that the percentage of cells that progress through the S phase was always lower in BHV-1-infected PBMCs than in control cells. This effect was not due to a defective activation of mitogen-stimulated PBMCs since BHV-1 only slightly affected the percentage of cells expressing BoCD25, a well-known lymphocyte activation marker. Furthermore, mimosine and cyclosporine A, two chemicals that inhibit entry into the S phase of the cell cycle by different pathways, did not affect the ability of BHV-1 to induce apoptosis. BHV-1-induced apoptosis also occurred in unstimulated PBMCs and interestingly, this was associated with the expression of c-myc and BoCD25 proteins both of which are related to cell cycle progression. All together, these data provide evidence demonstrating that BHV-1-induced apoptosis occurs at the G0/G1 phase of the cell cycle. [less ▲]

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See detailEmerging Roles for Proteinases in Cancer
Noël, Agnès ULg; Gilles, Christine ULg; Bajou, Khalid ULg et al

in Invasion & Metastasis (1997), 17(5), 221-39

Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer cure. The contribution of proteinases in these ... [more ▼]

Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer cure. The contribution of proteinases in these processes was initially thought to be the destruction of extracellular matrices. However, recent evidence suggests that they mainly affect tumor growth rather than invasion. Proteinases can indeed generate active matrix protein fragments, influence the release, the activation and the bioavailability of growth factors, and consequently modulate tumor cell growth, apoptosis and angiogenesis. Additionally, proteinases, their receptors and/or inhibitors can be directly involved in cell migration and in the processing or shedding of cell surface proteins. Further elucidation of the functions of proteinases is essential for the development of novel anticancer strategies. [less ▲]

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See detailL'homeopathie peut-elle trouver sa legitimite dans les resultats "positifs" d'une meta-analyse?
Scheen, André ULg

in Revue Médicale de Liège (1997), 52(11), 694-7

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See detailTumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers.
Polette, M.; Gilles, Christine ULg; Marchand, V. et al

in Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society (1997), 45(5), 703-9

Tumor cell-derived collagenase stimulatory factor (TCSF) stimulates in vitro the biosynthesis of various matrix metalloproteinases involved in tumor invasion, such as interstitial collagenase, gelatinase ... [more ▼]

Tumor cell-derived collagenase stimulatory factor (TCSF) stimulates in vitro the biosynthesis of various matrix metalloproteinases involved in tumor invasion, such as interstitial collagenase, gelatinase A, and stromelysin 1. The expression of TCSF mRNAs was studied in vivo, using in situ hybridization and Northern blotting analysis, in seven normal tissues and in 22 squamous cell carcinomas of the lung, and in seven benign proliferations and in 22 ductal carcinomas of the mammary gland. By in situ hybridization, TCSF mRNAs were detected in 40 of 44 carcinomas, in pre-invasive and invasive cancer cells of both lung and breast cancers. TCSF mRNAs and gelatinase A mRNAs were both visualized in the same areas in serial sections in breast cancers, and were expressed by different cells, tumor cells, and fibroblasts. The histological results were confirmed by Northern blot analysis, which showed a higher expression of TCSF mRNAs in cancers than in benign and normal tissues. These observations support the hypothesis that TCSF is an important factor in lung and breast tumor progression. [less ▲]

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See detailBilinguisme, traduction et histoire des textes dans l'Orient grec (Ier - IVe s. après J.-C.)
Rochette, Bruno ULg

in Revue d'Histoire des Textes (1997), 27

Vise à montrer l'intérêt que présentent les textes traduits pour l'étude de la transmission de l'original. Trois exemples de traductions du latin en grec, réalisées dans la Pars Orientis entre le Ier et ... [more ▼]

Vise à montrer l'intérêt que présentent les textes traduits pour l'étude de la transmission de l'original. Trois exemples de traductions du latin en grec, réalisées dans la Pars Orientis entre le Ier et le IVe s., sont étudiés : les Res gestae diui Augusti, les listes de mots compilées à partir de Virgile et de Cicéron sur papyrus, la uersio Graeca de la quatrième Bucolique de Virgile appartenant à l'Oratio ad Sanctorum coetum de Constantin le Grand. L'apport de ces traductions se situe sur deux plans. D'abord, constituant une tradition en soi, les traductions grecques d'œuvres latines permettent de connaître l'état du texte au moment de sa traduction et peuvent donc jouer un rôle dans l'ecdotique. Ensuite, ces traductions apportent une contribution à l'histoire de la littérature et des mentalités. La traduction d'un texte se situe dans un contexte culturel différent de celui dans lequel a été élaboré l'original. Loin de se contenter de traduire ad uerbum, le traducteur fait passer dans la version traduite des conceptions nouvelles, politiques, sociales ou religieuses. Ainsi, par exemple, le passage d'un régime politique à un autre (République-Empire) ou d'une conception religieuse à une autre (paganisme-christianisme) peut modifier radicalement la perspective du traducteur. [less ▲]

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See detailDetermination rapide par immunodosage de l'hemoglobine glyquee sur sang capillaire comparee a une methode d'affinite pour le boronate et capture d'ions sur sang veineux.
Bozet, Marie-Claire ULg; Gerard, Pascale ULg; Scheen, André ULg et al

in Annales de Biologie Clinique (1997), 55(2), 139-44

Measurement of glycosylated haemoglobin has become an essential tool in the management of diabetic patients. A recently developed device allows the rapid immuno-assay of HbA1c in 1 microliter capillary ... [more ▼]

Measurement of glycosylated haemoglobin has become an essential tool in the management of diabetic patients. A recently developed device allows the rapid immuno-assay of HbA1c in 1 microliter capillary blood obtained by a finger prick. In 100 ambulatory diabetic patients, we compared the results obtained with this method to those obtained in venous blood using a standard affinity chromatography laboratory method. Although both methods correlated (r = 0.88, p < 0.001), the mean +/- SD levels respectively obtained differed slightly (7.6 +/- 1.5 vs 79 +/- 1.4% p < 0.001). The 95% confidence interval of the difference was [-0.41. -0.14]. Considering a cut-off HbA1c value of 8%, as indicative of the need for treatment adjustment, 33 patients with the capillary blood immuno-assay method and 42 with the venous-blood affinity chromatography method were above that limit (Mc Nemar test, p < 0.05). In conclusion, the rapid assay of HbA1c in capillary blood can be useful for the management of some diabetic patients but the results are not readily exchangeable with those obtained from other standardized laboratory methods. Consequently, specific ranges and clinical decision limits must be determined. [less ▲]

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See detailRésumé des communications et livret guide des excursions
Petit, François ULg; Wastiaux, Cécile; Assani, Ali Arkamose et al

in Journées hydrologiques françaises (Commission des Hydrosystèmes fluviaux) Journées de terrain organisées en Ardenne et dans les Hautes fagnes (1997)

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See detailImplication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
Gilles, Christine ULg; Polette, M.; Seiki, M. et al

in Laboratory Investigation : Journal of Technical Methods & Pathology (1997), 76(5), 651-60

We have previously demonstrated that fibroblasts and invasive human breast carcinoma (HBC) cells specifically activate matrix metalloproteinase-2 (MMP-2) when cultured on 3-dimensional gels of type I ... [more ▼]

We have previously demonstrated that fibroblasts and invasive human breast carcinoma (HBC) cells specifically activate matrix metalloproteinase-2 (MMP-2) when cultured on 3-dimensional gels of type I collagen but not a range of other substrates. We show here the constitutive expression of membrane-type 1 (MT1)-MMP in both fibroblasts, and invasive HBC cell lines, that have fibroblastic attributes presumably acquired through an epithelial-to-mesenchymal transition (EMT). Treatment with collagen type I increased the steady-state MT1-MMP mRNA levels in these cells but did not induce either MT1-MMP expression or MMP-2 activation in noninvasive breast carcinoma cell lines, which retain epithelial features. Basal MT3-MMP mRNA expression had a pattern similar to that of MT1-MMP but was not up-regulated by collagen. MT4-MMP mRNA was seen in both invasive and noninvasive HBC cell lines and was also not collagen-regulated, and MT2-MMP mRNA was not detected in any of the HBC cell lines tested. These data support a role for MT1-MMP in the collagen-induced MMP-2-activation seen in these cells. In situ hybridization analysis of archival breast cancer specimens revealed a close parallel in expression of both collagen type I and MT1-MMP mRNA in peritumoral fibroblasts, which was correlated with aggressiveness of the lesion. Relatively high levels of expression of both mRNA species were seen in fibroblasts close to invasive tumor nests and, although only focally, in certain areas close to preinvasive tumors. These foci may represent hot spots for local degradation and invasive progression. Collectively, these results implicate MT1-MMP in collagen-stimulated MMP-2 activation and suggest that this mechanism may be employed in vivo by both tumor-associated fibroblasts and EMT-derived carcinoma cells to facilitate increased invasion and/or metastasis. [less ▲]

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See detailUltrasonographic examination of the proximal scutum in the horse.
Denoix, J. M.; Busoni, Valeria ULg; Olalla, M. J.

in Equine Veterinary Journal (1997), 29(2), 136-41

Normal and abnormal ultrasonographic images are presented of the proximal scutum (proximal sesamoid bones and palmar ligament) in the horse. Comparison between anatomical sections, MRI (magnetic resonance ... [more ▼]

Normal and abnormal ultrasonographic images are presented of the proximal scutum (proximal sesamoid bones and palmar ligament) in the horse. Comparison between anatomical sections, MRI (magnetic resonance imaging) and ultrasound scans enabled the authors to establish the normal ultrasonographic anatomy of the palmar fetlock. Nine cases of proximal scutum injuries were identified ultrasonographically, of which 4 are illustrated. On normal limbs, the facies flexoria of the proximal sesamoid bones appeared as a thin and regular hyperechoic line and the palmar ligament was regularly echogenic. Lesions of the proximal scutum, that could be documented ultrasonographically, included rupture of the palmar ligament, avulsion fractures of the proximal sesamoid bones and palmar ligament desmopathy. Thinning or degeneration of the palmar ligament, concurrent with osteolysis of the proximal sesamoid bones, were indicative of palmar ligament enthesopathy. Ultrasonographic examination provided essential information for an accurate diagnosis of proximal scutum damage. [less ▲]

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See detailLes téléports en Europe: état actuel et perspectives offertes par les "call centers"
Jacob, Damien ULg

in Revue Géographique de l'Est (1997), 37(4), 273-284

De manière à répondre à l'accroissement de l'offre et de la demande en télécommunications d'entreprises constaté ces dernières années, trois grandes catégories de téléports proposant des services à coûts ... [more ▼]

De manière à répondre à l'accroissement de l'offre et de la demande en télécommunications d'entreprises constaté ces dernières années, trois grandes catégories de téléports proposant des services à coûts partagés et les téléports " hub ", concentrant les flux de communication en un point central. Les téléports ciblent des entreprises exigeant un haut niveau de services en télécommunications, par exemple les centres d'appels téléphoniques. Cette activité, en pleine expansion en Europe, recherche une main-d'œuvre multilingue pouvant assurer par téléphone des services d'information, de conseil, de vente et d'après-vente. Les téléports peuvent donc devenir des outils attractifs pour attirer ce créneau particulièrement porteur en création d'emplois, même si ces derniers sont pour une bonne part une transformation d'anciennes tâches et paraissent potentiellement faciles à délocaliser vers des pays à faible coût du travail. [less ▲]

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See detailThe yeast genome directory.
Goffeau, A.; Hilger, F.; Portetelle, Daniel ULg et al

in Nature (1997), 387(5),

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See detailLe dessaisissement du juge d'instruction
Jacobs, Ann ULg

in Revue de Droit Pénal et de Criminologie (1997)

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See detailGlucose metabolism during bovine preimplantation development: analysis of gene expression in single oocytes and embryos.
Lequarré, Anne-Sophie ULg; Grisart, B.; Schuurbiers, N. et al

in Molecular Reproduction and Development (1997), 48(2), 216-26

Glucose metabolism of the bovine embryo is low during the first cleavages and increases sharply after the major resumption of the genome (8-16 cells). The mRNA level for genes involved in glucose ... [more ▼]

Glucose metabolism of the bovine embryo is low during the first cleavages and increases sharply after the major resumption of the genome (8-16 cells). The mRNA level for genes involved in glucose metabolism was tested by RT-PCR on individual oocytes and embryos at different stages of development. These genes were: glucose transport GLUT-1, hexokinase (HK), glucose-6-phosphatase-dehydrogenase (G6PDH), and glucose-phosphate-isomerase (GPI); actin was used as a reference transcript. RT-PCR results revealed three types of oocytes or embryos: positive with a PCR signal for each transcript considered, nul with no signal for any transcript, and heterogeneous with a PCR signal for some transcripts and none for others. The number of nul and heterogeneous samples was higher for slow than for fast-cleaving embryos (81% vs. 36%), and the proportion of positive embryos increased significantly at the 16-cell and morula stages (P < 0.002), suggesting a correlation between mRNA content and developmental capacity. In positive embryos, GLUT-1 level was reduced by half during maturation and fertilization. Actin and hexokinase mRNA levels decreased during the first cleavages, but significantly increased at the 16-cell and morula stages, respectively. GPI transcript remained stable throughout development, whereas there was a significant rise for G6PDH at the 4-cell stage, perhaps due to a polyadenylation process. Finally, the absence or decrease in intensity of several transcripts at the blastocyst stage suggests suboptimal culture conditions. [less ▲]

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See detailCharacterization of Clostridium perfringens isolated from necrotic enteritis of fowls.
Das, B. C.; Dutta, G. N.; Daube, Georges ULg et al

in Indian Journal of Animal Sciences (The) (1997), 67

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See detailSpecific Modulation Of The Fusogenic Properties Of The Alzheimer Beta-Amyloid Peptide By Apolipoprotein E Isoforms
Pillot, T.; Goethals, M.; Vanloo, B. et al

in European Journal of Biochemistry (1997), 243(3), 650-9

C-terminal fragments of the Alzheimer amyloid peptide (amino acids 29-40 and 29-42) have physico-chemical properties related to those of the fusion peptides of viral proteins and they are able to induce ... [more ▼]

C-terminal fragments of the Alzheimer amyloid peptide (amino acids 29-40 and 29-42) have physico-chemical properties related to those of the fusion peptides of viral proteins and they are able to induce the fusion of liposomes in vitro. We proposed that these properties could mediate a direct interaction of the amyloid peptide with cell membranes and account for part of the cytotoxicity of the amyloid peptide. In view of the epidemiologic and biochemical linkages between the pathology of Alzheimer's disease and apolipoprotein E (apoE) polymorphism, we examined the potential interaction between the three common apoE isoforms and the C-terminal fragments of the amyloid peptide. We show that, at low concentration, only apoE2 and apoE3 are potent inhibitors of the amyloid peptide fusogenic and aggregational properties, whereas the apoE4 isoform has no effect. We further show that the protective effect of apoE is mediated by the formation of stable apoE/amyloid peptide complexes, as determined by tryptophan emission fluorescence measurements and by gel electrophoresis. The interaction specificity between apoE2 and apoE3 and the amyloid fragments is demonstrated here, since other apolipoproteins (e.g. apolipoprotein A-I and A-II), with similar amphipathic structures, do not interact with the amyloid C-terminal fragments. Finally, we show that, reciprocally, the amyloid peptide can interact directly with the apoE2 and apoE3 isoforms to decrease or perturb their normal association with lipids. These data suggest that the 29-40 and 29-42 domains of the amyloid peptide could be critical for the amyloid-apoE interaction, and that apoE2 and apoE3 isoforms, but not apoE4, could play a protective role against the formation of amyloid aggregates and/or against their interaction with cellular membranes. [less ▲]

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See detailSporopodiopsis, a new genus of lichens (Ectolechiaceae) from S-E Asia
Sérusiaux, Emmanuël ULg

in Abstracta Botanica (1997), 21

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See detailBenchmarks for finite element modelling of bolted steel connections
Bursi, O.; Jaspart, Jean-Pierre ULg

in Journal of Constructional Steel Research (1997), 43(Nos 1-3),

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See detailLes aspects thérapeutiques de l'HTA
Krzesinski, Jean-Marie ULg

in Médisphère (1997), 68

Traiter l'hypertension artérielle n'améliore pas seulement le pronostic cardiovasculaire. L'étude de Wiklund (Suède) à partir de la population étudiée dans la Hot Study a permis de montrer que l ... [more ▼]

Traiter l'hypertension artérielle n'améliore pas seulement le pronostic cardiovasculaire. L'étude de Wiklund (Suède) à partir de la population étudiée dans la Hot Study a permis de montrer que l'abaissement de la pression artérielle améliorait l'humeur des hypertendus et ce, proportionnellement à la correction du niveau tensionnel. [less ▲]

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See detailLa prééclampsie est la conséquence d'un déficit de placentation: de la biologie aux considérations cliniques
Maquoi, Erik ULg; Schaaps, Jean-Pierre ULg; Jacobs, J. L. et al

in Revue Médicale de Liège (1997), 52(7), 478-84

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See detailLoss of type IV collagen alpha 5 and alpha 6 chains in human invasive prostate carcinomas
Dehan, Pierre ULg; Waltregny, David ULg; Beschin, Alain et al

in American Journal of Pathology (1997), 151(4), 1097-104

Type IV collagen, a major component of basement membranes, is organized in a network responsible for the mechanical resistance of the basement membranes. It also plays a key role in epithelial cell ... [more ▼]

Type IV collagen, a major component of basement membranes, is organized in a network responsible for the mechanical resistance of the basement membranes. It also plays a key role in epithelial cell adhesion to basement membranes. This study was designed to investigate the distribution of type IV collagen alpha-chains in normal, preneoplastic, and malignant prostate basement membranes. For this purpose, immunohistochemistry using specific antibodies raised against the different alpha-chains of type IV collagen was performed in eight normal samples, six prostatic intraepithelial neoplasia, and 20 malignant lesions of the prostate. Our results demonstrate the presence of the "novel" alpha 5 (IV) and alpha 6 (IV) chains along with the "classical" alpha 1 (IV)/alpha 2 (IV) chains in the basement membrane of the normal prostate gland. The alpha 3 (IV) chain was never detected in any prostate specimen. Prostatic intraepithelial neoplasia showed a similar immunostaining pattern to that found in normal glands. In cancer gland basement membranes, we demonstrate for the first time a specific loss of the alpha 5 (IV) and alpha 6 (IV) chains, whereas the classical alpha 1 (IV) and alpha 2 (IV) chains were consistently exhibited. Additionally, type VII collagen colocalized with alpha 5 (IV) collagen chain, and these two proteins, which were always observed in normal and prostatic intraepithelial neoplasia gland basement membranes, were lost in invasive carcinoma basement membranes. This observation raises questions about the possible association or cooperation between alpha 5 (IV)/alpha 6 (IV) chains and anchoring fibrils in prostate glands basement membrane. [less ▲]

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See detailLe rôle de l'officier de l'état civil requis de célébrer un mariage présumé simulé
Paris, Catherine ULg

in Revue Trimestrielle de Droit Familial (1997)

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See detailZiemniak w Belgii
Burny, Philippe ULg; Gazinski, Benon

in Rolnicze abc (1997), 6(83), 20

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See detailMonotonous stability for neutral fixed points
Bair, Jacques ULg; Haesbroeck, Gentiane ULg

in Bulletin of the Belgian Mathematical Society Simon Stevin (1997), 4(5), 639-646

We give subtle, simple and precise results about the convergence or the divergence of the sequence (x(n)), where x(j) = f(x(j-1)) for every integer j, when the initial element x(0) is in the neighbourhood ... [more ▼]

We give subtle, simple and precise results about the convergence or the divergence of the sequence (x(n)), where x(j) = f(x(j-1)) for every integer j, when the initial element x(0) is in the neighbourhood of a neutral fixed point, i.e. a point x* such that f(x*) = x* with \f'(x*)\ = 1 (where f is a C-infinity function defined on a subset of R). [less ▲]

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See detailThe Degradation Of L-Tyrosine To Phenol And Benzoate In Pig Manure - The Role Of 4-Hydroxy-Benzoate
Antoine, P.; Taillieu, X.; Thonart, Philippe ULg

in Applied Biochemistry and Biotechnology (1997), 63-5

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See detailL'hypoglycemie du patient diabetique. Recommendations of ALFEDIAM (French Language Association for the Study of Diabetes and Metabolic Diseases.
Grimaldi, A.; Slama, G.; Tubiana-Rufi, N. et al

in Diabètes & Métabolism (1997), 23(1), 100-8

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See detailUse of the alpha parameter method to calculate matrix corrections for infinitely thick targets (TTPIXE) with two different incident beam energies
Delbrouck Habaru, J.; Roelandts, I.; Strivay, David ULg et al

in Nuclear Instruments & Methods in Physics Research Section B (1997), 129(1), 92-100

The alpha parameter correction method for calculating matrix effects in PIXE data does not require a priori knowledge of the major element composition of the matrix but implies the determination of a so ... [more ▼]

The alpha parameter correction method for calculating matrix effects in PIXE data does not require a priori knowledge of the major element composition of the matrix but implies the determination of a so-called alpha parameter linking two independent phenomena: X-ray absorption and proton energy loss. The method extrapolated to the infinitely thick targets (TTPIXE) has been previously studied using two PIXE measurements in two different geometric configurations. The present Study deals with the possibility of using pairs of PIXE measurements at two different energies to obtain the alpha corresponding to thick samples (TTPIXE). The experimental conditions and error minimization problems are discussed. General tables allowing an easy use of the method are presented. [less ▲]

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See detailLe contrôle des juridictions de fond sur la désignation par procureur général du magistrat compétent en application de l'article 155, alinéa 2, du Code judiciaire
Michiels, Olivier ULg

in Journal des Tribunaux (1997)

La note publiée sous un arrêt prononcé par la Cour de cassation le 8 octobre 1996 fait le point sur le contrôle par les juridictions de fond sur la désignation par procureur général du magistrat compétent ... [more ▼]

La note publiée sous un arrêt prononcé par la Cour de cassation le 8 octobre 1996 fait le point sur le contrôle par les juridictions de fond sur la désignation par procureur général du magistrat compétent en application de l'article 155, alinéa 2, du Code judiciaire pour exercer les poursuites devant les juridictions répressives dans les hypothèses de concours entre des infractions de droit commun et de droit pénal social. [less ▲]

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See detailLes comportements des enseignants dans la perspective d'un traitement différencié des élèves
Piéron, Maurice; Ledent, Maryse; Pirottin, Véronique et al

in Revue de l'Education Physique (1997), 4

La pédagogie basée sur la théorie des "rythmes d'apprentissage" accorde une place privilégiée à l'individualisation et contredit le principe d'une programmation uniforme, valable pour tous. Toute classe ... [more ▼]

La pédagogie basée sur la théorie des "rythmes d'apprentissage" accorde une place privilégiée à l'individualisation et contredit le principe d'une programmation uniforme, valable pour tous. Toute classe est hétérogène, chaque enfant étant singulier, différent dans ses valeurs, ses attitudes, ses potentialités et ses compétences. Chacun apprend à un rythme différent, plus rapidement que la moyenne dans des domaines, moins rapidement dans d'autres. ... [less ▲]

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See detailJungermannia paroica (Schiffn.) Grolle in the Vosges, new to France
Vanderpoorten, Alain ULg; Sotiaux, André ULg

in Journal of Bryology (1997), 19

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See detailPour l’optimisation de la stratégie thérapeutique dans la maladie osseuse de Paget
Reginster, Jean-Yves ULg; Gennari, C; Hosking, DJ et al

in Revue du Rhumatisme (1997), 64(4), 221-223

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See detailNote on the measurement of the thermal conductivity and the double peak structure in high-Tc superconductors
Bougrine, Hassan ULg; Pekala, M.

in Superconductor Science & Technology (1997), 10(8), 621-623

We show that low-temperature measurements of the thermal conductivity of high-T-c superconductors can sometimes reveal a double peak structure depending on the experimental set-up used.

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See detailLa problématique de la matière grasse : aspects théoriques
Thonart, Philippe ULg; Destain, Jacqueline ULg; Antoine, P. et al

in Tribune de l'Eau (La) (1997), 586/2

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See detailMetacognitive realism : A cognitive style or a learning strategy ?
Jans, Véronique; Leclercq, Dieudonné ULg

in Educational Psychology (1997), 17(1-2), 101-110

Learning implies the learner's ability to make a series of decisions and, in particular, the capacity to assess the quality and reliability of one's own knowledge incapsulated in the question: 'How far do ... [more ▼]

Learning implies the learner's ability to make a series of decisions and, in particular, the capacity to assess the quality and reliability of one's own knowledge incapsulated in the question: 'How far do I already know the content I am supposed to learnt?' The authors address the following issues: (1) Is realism in metacognition a stable trait in learners?; (2) If not, by what is it influenced?. After a short review of the literature on the topic and the examination of experimental evidence, metacognition is considered as both a style and a strategy. The need for a taxonomy of metacognitive realism is demonstrated in order to clarify the topic and to facilitate applied research. [less ▲]

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See detailPolyclonal Bovine Sera But Not Virus-Neutralizing Monoclonal Antibodies Block Bovine Leukemia Virus (Blv) Gp51 Binding To Recombinant Blv Receptor Blvrcp1
Orlik, O.; Ban, J.; Hlavaty, J. et al

in Journal of Virology (1997), 71(4),

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See detailLa cavernostomie: une ancienne technique parfois efficace dans le traitement des abcès pulmonaires
Defraigne, Jean-Olivier ULg; Siquet, J.; Limet, Raymond ULg

in Revue Médicale de Liège (1997), 52(7), 498-501

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See detailLa nature de l'acte juridique attesté par l'O. Mich. III 1098
Straus, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1997), LXXII(143), 128-129

O. Mich. III 1098 attests the delivery of a slave as a surety of a loan.

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See detailDesign for an Ipriflavone Multicenter European Fracture Study
Reginster, Jean-Yves ULg; Bufalino, L.; Christiansen, C. et al

in Calcified Tissue International (1997), 61(Suppl 1), 28-32

In order to investigate the efficacy of ipriflavone (i.p.) on the prevention of vertebral fractures and the effect on bone mineral density (BMD) in women with postmenopausal osteoporosis, a large ... [more ▼]

In order to investigate the efficacy of ipriflavone (i.p.) on the prevention of vertebral fractures and the effect on bone mineral density (BMD) in women with postmenopausal osteoporosis, a large multicentric European study was designed and is presently ongoing. Included in the study were 460 Caucasian, nonobese postmenopausal women aged > 45 and < 75 years, menopaused for at least 12 months. Inclusion was on the basis of a lumbar bone mineral density (BMD) lower than 2 SD compared with healthy women aged 50 years, corresponding to values below 0.860 g/cm2 (antero-posterior measurement) by Hologic QDR 1000. Women with prevalent vertebral fractures were excluded as well as those presenting secondary osteoporosis or having been treated with medications that could affect bone metabolism. This study was designed as a 3-year, double-blind, placebo-controlled, parallel group study that randomized the women to the oral administration of either 3 x 200 mg/day of i.p. or placebo. All patients received a daily supplement of 500 mg calcium. The primary purpose of the study was to evaluate the efficacy of i.p. in preventing vertebral nontraumatic fractures. Fracture is defined here as a > or = 20% decrease in any anterior, central, or posterior T4-L4 vertebral height. Blinded vertebral X-ray readings and vertebral morphometry have been centralized in an independent Center, with standardized evaluation of two experts. Power calculations have been based on the hypothesis that 21% of placebo-treated patients would fracture within 3 years and that treatment with i.p. would lead to a 50% reduction in the incidence of fracture. Statistical tests have been designed to have a power of 80%, with a type I error equal to 5%. Secondary endpoints were changes in vertebral, radial, and femoral BMD. Centralized controls on 100% BMD scans would ensure the good quality of BMD readings. This study should verify the hypothesis that i.p. significantly decreases the risk of vertebral fracture in postmenopausal, osteoporotic women. [less ▲]

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See detailLes protéases stromales dans la progression cancéreuse mammaire
Foidart, Jean-Michel ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1997), 152(5), 229-35235-7

Matrix metalloproteases represent a family of proteases secreted as latent inactive enzymes able to degrade the majority of extracellular matrix components. These enzymes are overexpressed during several ... [more ▼]

Matrix metalloproteases represent a family of proteases secreted as latent inactive enzymes able to degrade the majority of extracellular matrix components. These enzymes are overexpressed during several pathological tissue remodelings including tumor progression and tumor invasion. It was indeed classically admitted that matrix metalloproteases involved in tumoral progression were preferentially expressed by cancerous cells. Our studies on gelatinase A and stromelysin-3 have, however, demonstrated that their messenger RNAS are detected in fibroblasts of the peritumoral stroma in human mammary carcinoma and not in the cancerous cells themselves. By immunohistochemistry, we have detected gelatinase A in the cytoplasm of fibroblasts and at the surface of the tumor cells. This membrane localization of the protein could result from its binding, following secretion by the neighbouring stromal cells, to a specific binding site expressed at the surface of the carcinoma cells. These cells are indeed able to induce an increased proteolytic activity by enhancing the transcription of these enzymes by peritumoral fibroblasts. These enzymes represent therefore potential targets for the development of new therapeutic strategies. [less ▲]

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See detailThe Spectrum of Ne V
Bastin, Thierry ULg; Biémont, Emile ULg; Dumont, Paul-Dominique ULg et al

in Physica Scripta (1997), 55

A new investigation of the Ne V spectrum is reported. The beam-foil method has been used to produce spectra at two different energies (1.2 MeV and 2.5 MeV) between 450 and 11OOA Sixty-five lines of Ne V ... [more ▼]

A new investigation of the Ne V spectrum is reported. The beam-foil method has been used to produce spectra at two different energies (1.2 MeV and 2.5 MeV) between 450 and 11OOA Sixty-five lines of Ne V have been newly identified. Fifty levels have been determined for the first time and energies have been revised for seven levels. [less ▲]

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See detailThe Effects of Hypertonic Saline in Healthy and Diseased Animals
Cambier, Carole ULg; Ratz, V.; Rollin, Frédéric ULg et al

in Veterinary Research Communications (1997), 21(5), 303-316

In this review, the pharmacological effects of administering hypertonic solutions to both healthy animals and during experimentally induced diseases are considered with a view to understanding the ... [more ▼]

In this review, the pharmacological effects of administering hypertonic solutions to both healthy animals and during experimentally induced diseases are considered with a view to understanding the mechanisms behind the possible clinical efficacy of such treatment. The review focuses successively on haemorrhagic shock, endotoxic shock and hypokalaemic metabolic alkalosis. How hypertonic saline solutions affect oxygen transport by haemoglobin is also considered. [less ▲]

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See detailEvaluation of pleural diseases with FDG-PET imaging: preliminary report.
Bury, Thierry ULg; Paulus, P; Dowlati, A et al

in Thorax (1997), 52(2), 187-9

BACKGROUND: Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis ... [more ▼]

BACKGROUND: Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis of pleural disease was investigated in 25 patients. METHODS: PET was performed on each subject before invasive procedures were used to determine the aetiological diagnosis. The PET data were analysed by visual interpretation of coronal, sagittal, and transverse slices. RESULTS: Sixteen patients were found to have malignant pleural disease and nine had benign disease. All patients with histologically confirmed malignant disease showed FDG uptake within the pleural thickening which was intense in 14 cases and moderate in two. PET imaging showed the absence of FDG uptake and correctly categorised seven non-malignant lesions. Two patients with infectious pleural diseases showed a localised and moderate FDG uptake. CONCLUSION: Our preliminary results suggest that FDG-PET could be an effective tool for differentiating between benign and malignant pleural diseases. [less ▲]

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See detailThe 118-135 Peptide Lot The Human Prion Protein Forms Amyloid Fibrils And Induces Liposome Fusion
Pillot, T.; Lins, Laurence ULg; Goethals, M. et al

in Journal of Molecular Biology (1997), 274(3), 381-93

The prion protein (PrPC) is a glycoprotein of unknown function normally found at the surface of neurons and of glial cells. It is involved in diseases such as bovine spongiform encephalopathy, and ... [more ▼]

The prion protein (PrPC) is a glycoprotein of unknown function normally found at the surface of neurons and of glial cells. It is involved in diseases such as bovine spongiform encephalopathy, and Creutzfeldt-Jakob disease in the human, where PrPC is converted into an altered form (termed PrPSc). PrPSc is highly resistant towards proteolytic degradation and accumulates in the central nervous system of affected individuals. By analogy with the pathological events occuring during the development of Alzheimer's disease, controverses still exist regarding the relationship between amyloidogenesis, prion aggregation and neuronal loss. To unravel the mechanism of PrP neurotoxicity and understand the interaction of PrP with cellular membranes, a series of natural and variant peptides spanning residues 118 to 135 of PrP was synthesized. The potential of these peptides to induce fusion of unilamellar lipid vesicles was investigated. According to computer modeling calculations, the 120 to 133 domain of PrP is predicted to be a tilted lipid-associating peptide, and to insert in a oblique way into a lipid bilayer through its N-terminal end. In addition to amyloidogenic properties exhibited in vitro by these peptides, peptide-induced vesicle fusion was demonstrated by several techniques, including lipid- and core-mixing assays. Elongation of the 120 to 133 peptide towards the N- and C-terminal ends of the PrP sequence showed that the 118 to 135 PrP peptide has maximal fusogenic properties, while the variant peptides had no effect. Due to their high hydrophobicity, all peptides tested were able to interact with liposomes to induce leakage of encapsulated calcein. We demonstrate also that the propensity of the peptides to fold as an alpha-helix increases their fusogenic activity, thus accounting for the maximal fusogenic activity of the most stable helix at residues 118 to 135. These data suggest that, by analogy with the C-terminal domain of the beta-amyloid peptide, the fusogenic properties exhibited by the prion peptides might contribute to the neurotoxicity of these peptides by destabilizing cellular membranes. [less ▲]

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See detailOn the use of HF as a reference for the comparison of stratospheric observations and models
Chipperfield, M. P.; Burton, M.; Bell, W. et al

in Journal of Geophysical Research (1997), 102(11D), 12901-12919

Hydrogen fluoride (HF) is often used as a simple reference for other column observations of chemically active stratospheric species. However, seasonal and shorter timescale variations in column HF make ... [more ▼]

Hydrogen fluoride (HF) is often used as a simple reference for other column observations of chemically active stratospheric species. However, seasonal and shorter timescale variations in column HF make its use as a reference more complicated. In this paper we characterize the expected magnitude of these variations in HF, and variations of ratio quantities involving HF, using a two-dimensional (2-D) photochemical model and two versions of a three-dimensional (3-D) transport model. The 2-D model predicts that the column ratios HNO3/HF and HCl/HF increase from midlatitudes to the tropics, although this is very sensitive to HCl and HNO3 abundances in the tropical upper troposphere. Seasonal variations in vertical motion modifys the predicted ratios; for example, wintertime descent at high latitudes decreases HCl/HF. The ratio HNO3/HF at high latitudes is strongly modified by seasonal variations in the chemical partitioning of the odd nitrogen (NOy) species. We compare these model predictions with ground-based Fourier transform infrared spectroscopy (FTIR) observations of HF along with HCl, ClONO2 and HNO3 obtained at eight northern hemisphere sites between October 1994 and July 1995. We investigate quantitatively how HF can be used as a tracer to follow the evolution of observations at a single station and to intercompare results from different stations or with photochemical models. The magnitude of the 3-D model HF column agrees well with the observations, except on some occasions at high latitudes, giving indirect support for the important role of COF2 in the stratospheric inorganic fluorine budget. The observed day-to-day variability in the column ratios HCl/HF and HNO3/HF is much larger at high latitudes. This variability is reproduced in the 3-D models and is due to horizontal motion. Short timescale vertical displacement of the species profiles is estimated to have a small effect on the column ratios. In particular, we analyze the usefulness of the observed column ratio (ClONO2 + HCl)/HF as an indicator for chlorine activation. Current measurement uncertainties limit the degree of activation which can be unambiguously detected using this observed quantity, but we can determine that chlorine-activated air was observed above Aberdeen (58 degrees N) on 6 days in late January 1995. [less ▲]

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See detailInfluence of Diazepam on Contingent Negative Variation
Papart, Patrick ULg; Ansseau, Marc ULg; Timsit-Berthier, M.

in Human Psychopharmacology (1997), 12

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See detailDuplication of a vertebral artery associated with epidermoid cyst of the posterior fossa.
Weis, J.; Reul, J.; Mayfrank, L. et al

in European radiology (1997), 7(3), 412-4

A case of a duplication of the left vertebral artery associated with a premedullary epidermoid cyst at the level of the foramen magnum is described. The close proximity of the two malformative lesions in ... [more ▼]

A case of a duplication of the left vertebral artery associated with a premedullary epidermoid cyst at the level of the foramen magnum is described. The close proximity of the two malformative lesions in the present case and the overlap of the periods when such developmental abnormalities can arise suggest that they might be causally linked. [less ▲]

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See detailClostridium perfringens urease genes are plasmid-borne.
Dupuy, B.; Daube, Georges ULg; Popoff, M. R. et al

in Infection and Immunity (1997), 65

Although many bacteria are ureolytic, and in some cases urease acts as a virulence factor, the urease phenotype has not been analyzed in the anaerobic pathogen Clostridium perfringens. In this study, ;2 ... [more ▼]

Although many bacteria are ureolytic, and in some cases urease acts as a virulence factor, the urease phenotype has not been analyzed in the anaerobic pathogen Clostridium perfringens. In this study, ;2% of C. perfringens strains, representing the principal biotypes, were found to harbor the urease structural genes, ureABC, and these were localized on large plasmids that often encode, in addition, the lethal « or i toxins or the enterotoxin. This represents the first report of a plasmid-encoded urease in a gram-positive bacterium. The C. perfringens enzyme was highly similar to the ureases of other bacteria and cross-reacted with antibodies raised against the urease purified from Helicobacter pylori. Urease production was inhibited by urea and induced under growth conditions where the availability of nitrogen sources was limiting. To date, this form of regulation has been observed only for chromosomal ureABC genes. [less ▲]

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See detailEmergency Coronary Stenting with Wiktor Stent N Immediate and Late Results.
Bertrand, Olivier; Legrand, Victor ULg; Bilodeau et al

in The Journal of invasive cardiology (1997), 9(1), 2-9

In case of failed angioplasty, coronary stenting has gradually emerged as a non-surgical method to restore vessel patency and optimize coronary blood flow. There is still little clinical and angiographic ... [more ▼]

In case of failed angioplasty, coronary stenting has gradually emerged as a non-surgical method to restore vessel patency and optimize coronary blood flow. There is still little clinical and angiographic information on the use of radiopaque single loose interdigitating wire stents in angioplasty complicated by threatened or acute closure. Seventy-one patients received Wiktor stents after threatened vessel closure in 53 cases and acute closure in 18 cases. Stent delivery was successful in 98%. In-hospital death occurred in 1 case (1.4%). Stents occlusion were faced in 10 cases (14%), of which 6 presented early and 4 late after the procedure. Urgent bypass surgery was needed in 9 cases (12%) and 7 patients (10%) developed acute myocardial infarction. Serious bleeding complications occurred in 7 cases (10%) and vascular repair was performed in 4 patients (5%). During a follow-up of 20 +/- 10 months, 2 patients died, no myocardial infarction was observed and recurrence of angina was noted in 17 patients (24%). Angiographic analysis showed an acute gain in minimal lumen diameter of 1.71 +/- 0.22 mm and a late loss of 0.63 +/- 0.17 mm. Angiographic restenosis (diameter stenosis > 50%) presented in 20% of patients. Therefore, Wiktor stenting yields similar results than currently used stents in acute closure and strictly defined threatened vessel closure following angioplasty. [less ▲]

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See detailMiospores from the type locality of the Middle Famennian Esneux Formation in the Ourthe Valley, eastern Belgium
Loboziak, S.; Avkhimovitch, V.I.; Streel, Maurice ULg

in Annales de la Société Géologique de Belgique (1997), 119(2), 111-118

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See detailTwo Members Of The Human Mageb Gene Family Located In Xp21.3 Are Expressed In Tumors Of Various Histological Origins
Lurquin, C.; De Smet, C.; Brasseur, F. et al

in Genomics (1997), 46(3), 397-408

Genes of the MAGE family direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. Twelve closely related MAGE genes are located in the Xq28 region ... [more ▼]

Genes of the MAGE family direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. Twelve closely related MAGE genes are located in the Xq28 region. These genes share 60-98% nucleotide identity in their coding region. The presence of homologous genes in a region of Xp21.3 has been reported previously. We obtained the complete sequence of a 42-kb stretch of this region. It contains four MAGE-related genes, which we propose to name MAGE-B1, B2, B3, and B4 (HGMW-approved symbols MAGEB1, MAGEB2, MAGEB3, and MAGEB4). The coding regions of these genes share 66-81% nucleotide identity and show 45-63% identity with those of the MAGE genes located in Xq28. Like the MAGE genes located in Xq28, the MAGE-B genes are silent in normal tissues with the exception of testis. Like MAGE-1, 2, 3, 4, 6 and 12 (HGMW-approved symbols MAGEA1, 2, 3, 4, 6, and 12), genes MAGE-B1 and MAGE-B2 are expressed in a significant fraction of tumors of various histological types. The transcription of MAGE-B1 and MAGE-B2 can be induced by 5-aza-2'-deoxycytidine, suggesting that the activation of these genes in tumors results from a demethylation process. [less ▲]

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See detailLack Of Mutation In The Waf1/Cip1 Gene During Bovine Leukemia Virus-Induced Leukemogenesis
Dequiedt, Franck ULg; Willems, Luc ULg; Kerkhofs, P. et al

in Veterinary Immunology and Immunopathology (1997), 59(3-4),

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See detail"De l'Olympe au réseau..." Comment les philologues classiques allemands font face aux réalités contemporaines
Rochette, Bruno ULg

in Bulletin de la Fédération des Professeurs de Grec et de Latin (1997), 108(septembre-octobre), 6-7

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See detailPlasma bovine pregnancy-associated glycoprotein concentrations throughout gestation in relationship fetal number in the cow
Patel, Osman V; Sulon, Joseph ULg; Beckers, Jean-François ULg et al

in European Journal of Endocrinology (1997), 137

This study characterized the peripheral plasma bovine pregnancy-associated glycoprotein (bPAG) profile throughout gestation and examined the effect of stage of gestation and fetal number on this profile ... [more ▼]

This study characterized the peripheral plasma bovine pregnancy-associated glycoprotein (bPAG) profile throughout gestation and examined the effect of stage of gestation and fetal number on this profile in Holstein cows after non-surgical embryo transfer. Cows (n = 12) were divided into three groups: group 1 = normal singleton pregnancies (n = 5); group 2 = normal twin pregnancies (n = 5); group 3 = abnormal twin pregnancies (n = 2). Blood was collected about every third day from day 0 (defined as the first day of standing estrus), then daily for the last 10 days of gestation, and sampling was stopped one day postpartum. The time-related changes in plasma bPAG concentrations were significantly (P < 0.01) affected by the stage of gestation and fetal number (P < 0.01), except during the last 10 days of gestation. In both normal pregnancy groups, bPAG concentration increased rapidly during the first trimester (0.5 +/- 0.1 to 14.6 +/- 1.7 ng/ml and 1.0 +/- 0.6 to 21.8 +/- 4.8 ng/ml, in singleton and twin-bearing groups respectively), then progressively between days 160 and 20 prepartum (31.6 +/- 6.2 to 114.3 +/- 31.3 ng/ml and 41.6 +/- 7.4 to 155.8 +/- 36.6 ng/ml in singleton and twin-bearing cows respectively). The mean concentration between days 20 and 10 prepartum approximately tripled (P < 0.001) in both these groups of cows (114.3 +/- 31.1 to 493.0 +/- 75.3 ng/ml and 155.8 +/- 36.6 to 409.3 +/- 114.7 ng/ml in singleton and twin-bearing cows respectively), but between days 10 prepartum and parturition the values increased about threefold (P < 0.01) in the singleton group (493.0 +/- 75.3 to 1352.8 +/- 286.5 ng/ml) and fivefold (P < 0.001) in the twin-bearing group (409.3 +/- 114.7 to 2154.0 +/- 505.7 ng/ml). The two cows in group 3 that gave birth prematurely to a stillborn calf or to a schistosomus reflexus calf exhibited an aberrant bPAG profile. Our results indicate that peripheral bPAG concentrations are correlated to the stage of gestation and fetal number, and that the profile of the peripheral plasma concentrations provides a useful indication of the feto-placental status. [less ▲]

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See detailEtudes phénoménologiques
Ryle, Gilbert; Leclercq, Bruno ULg

in Recherches Husserliennes (1997), 7

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See detailLe rôle de l'expert
Boxho, Philippe ULg

in Société d'étude du dommage corporel (1997)

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See detailLow Thiamine Diphosphate Levels in Brains of Patients with Frontal Lobe Degeneration of the Non-Alzheimer's Type
Bettendorff, Lucien ULg; Mastrogiacomo, Frank; Wins, Pierre et al

in Journal of Neurochemistry (1997), 69(5), 2005-2010

We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or ... [more ▼]

We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or frontotemporal dementia with five age-, postmortem delay-, and agonal status-matched control subjects. Our results reveal a 40-50% decrease in thiamine diphosphate (TDP) in the cortex of FNAD patients, whereas thiamine monophosphate was increased 49-119%. TDP synthesizing and hydrolyzing enzymes were unaffected. The activity of citrate synthase, a mitochondrial marker enzyme, was decreased in the frontal cortex of patients with FNAD, but no correlation with TDP content was found. These results suggest that decreased contents of TDP, which is essentially mitochondrial, is a specific feature of FNAD. As TDP is an essential cofactor for oxidative metabolism and neurotransmitter synthesis, and because low thiamine status (compared with other species) is a constant feature in humans, a nearly 50% decrease in cortical TDP content may contribute significantly to the clinical symptoms observed in FNAD. This study also provides a basis for a trial of thiamine, to improve the cognitive status of the patients. [less ▲]

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See detailUse of recombinant human erythropoietin after allogeneic bone marrow transplantation
Hermanne, J.-P.; Beguin, Yves ULg

in Erythropoiesis (1997), 8

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See detailEffects of Growth and Breed on Direct Static Measurements of Chest Wall Compliance in Cattle
Desmecht, Daniel ULg; Rollin, Frédéric ULg; Linden, Annick ULg et al

in Research in Veterinary Science (1997), 62(1, Jan-Feb), 1-5

Chest wall compliance (CW) was measured in 59 conscious standing calves, aged six to 162 days, which were breathing air spontaneously through a face mask. The airways were occluded at the end of ... [more ▼]

Chest wall compliance (CW) was measured in 59 conscious standing calves, aged six to 162 days, which were breathing air spontaneously through a face mask. The airways were occluded at the end of inspiration in order to elicit the Hering-Breuer reflex, the effectiveness of which was ensured by the presence of a plateau on the tracings of airway opening and oesophageal pressure (Pes). CW was measured directly from the inspired volume of the occluded breath and changes in Pes generated by the recoil of the relaxed chest wall. This airway-occlusion technique yielded reproducible CW values similar to those measured by classical invasive methods. The ratio of CW to bodyweight in the growing calves (sCW) ranged from 2.2 to 11.5 ml cmH2O-1 kg-1 and was correlated negatively with age: (log sCW = 0.91-0.003 x age, r = 0.68), the rate of decline corresponding well to the multispecies allometric growth relationship. [less ▲]

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See detailComment j'explore ... le syndrome d'insulinoresistance grace a ses marqueurs biologiques.
Luyckx, Françoise ULg; Scheen, André ULg; Gielen, Jean-Louis ULg et al

in Revue Médicale de Liège (1997), 52(10), 686-91

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See detailTowards interbreed IBD fine mapping of the mh locus: double-muscling in the Asturiana de los Valles breed involves the same locus as in the Belgian Blue cattle breed.
Dunner, S.; Charlier, Carole ULg; Farnir, Frédéric ULg et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (1997), 8(6), 430-5

The Spanish "Asturiana" cattle breed is characterized by the segregation of a genetically determined muscular hypertrophy referred to as double-muscling or "culones". We demonstrate by linkage analysis ... [more ▼]

The Spanish "Asturiana" cattle breed is characterized by the segregation of a genetically determined muscular hypertrophy referred to as double-muscling or "culones". We demonstrate by linkage analysis that this muscular hypertrophy involves the mh locus previously shown to cause double-muscling in the Belgian Blue cattle breed, pointing towards locus homogeneity of this trait across both breeds. Moreover, using a twopoint and multipoint maximum likelihood approach, we show that flanking microsatellite markers are in linkage disequilibrium with the mh locus in both breeds albeit with different alleles. Finally, we discuss how allelic homogeneity across breeds might be exploited to achieve efficient genetic fine-mapping of the mh locus. [less ▲]

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See detail5-(Diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide : Synthesis and Evaluation of Spin Trapping Properties
Roubaud, Valérie; Mercier, Anne; Olive, Gilles ULg et al

in Journal of the Chemical Society. Perkin Transactions 2 (1997), 9

A new spin trap, the 5-(diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide (3), is prepared through a four-step synthetic route. The in vitro spin trapping properties of 3 have been ... [more ▼]

A new spin trap, the 5-(diethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide (3), is prepared through a four-step synthetic route. The in vitro spin trapping properties of 3 have been investigated and the hydroxyl and superoxide spin adducts characterised. The persistence of the superoxide spin adduct obtained with 3 is compared with those of the analogues obtained with DEPMPO [5-(diethoxyphosphoryl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide] and DMPO in both phosphate buffer and pyridine. In 0.1 M phosphate buffer at pH 7.0, the HOO-3? adduct is found to be 2.8 times more persistent than HOO-DMPO?, but 5.7 times less than HOO-DEPMPO?. In phosphate buffer, HOO-3? decomposes to give HO-3?. The stereoselectivity of the addition of free radicals on 3 is generally poor, and mixtures of diastereomers have been observed by EPR. The overall spin trapping behaviour of nitrone 3 is more similar to that of DMPO than that of DEPMPO. [less ▲]

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See detailUsefulness of 18fdg Positron Emission Tomography in Detection and Follow-up of Digestive Cancers
Paulus, P.; Hustinx, Roland ULg; Daenen, Frédéric ULg et al

in Acta Gastro-Enterologica Belgica (1997), 60(4, Oct-Dec), 278-80

PET is a diagnostic method that creates high resolution, 3 dimensional tomographic images of the distribution of positron emitting radionuclides in the human body. Recent technological developments allow ... [more ▼]

PET is a diagnostic method that creates high resolution, 3 dimensional tomographic images of the distribution of positron emitting radionuclides in the human body. Recent technological developments allow the use of whole-body PET devices in clinical oncology. 18FDG is a glucose analog transported and competitively used with glucose reflecting the increased glucose metabolism into malignant cells. Differential diagnosis between chronic pancreatitis and pancreatic cancer is already a well-documented indication. For initial staging of gastro-esophageal and colorectal tumours, results are preliminary but the clinical impact seems to be rather limited. At present, the major indication of FDG-PET is the detection and staging of colorectal cancer recurrences. FDG-PET allows the differentiation between scared tissue and tumour when structural imaging is often confusing. In the same time, the whole-body imaging capability provides unique information that can modify loco-regional and liver staging. Overall, FDG-PET affects the clinical management of 30 to 40% of these patients. Quantitative assessment of therapeutic response to chemotherapy regimen appears to be one of the most promising applications of FDG-PET. Since the most effective therapy of colorectal cancer are often surgical, the role of chemotherapy in colorectal cancer remains limited to adjuvant therapy and in advanced disease. However, FDG-PET could be of great value in assessing the response of oesophageal carcinomas to chemo-radio therapy, before surgery. In our experience, FDG-PET appears to be the first line diagnostic method in the detection and staging of colorectal recurrence and differential diagnosis of pancreatic tumour versus chronic pancreatitis. [less ▲]

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See detailAdjusting to changes in the time of reinforcement: peak-interval transitions in rats.
Lejeune, H.; Ferrara, André ULg; Simons, F. et al

in Journal of Experimental Psychology. Animal Behavior Processes (1997), 23(2), 211-31

Thirty rats received training on a peak-interval procedure, where a baseline with a 20-s time of reinforcement was interspersed among cyclic transitions to other reinforcement time values (10, 20, 30, or ... [more ▼]

Thirty rats received training on a peak-interval procedure, where a baseline with a 20-s time of reinforcement was interspersed among cyclic transitions to other reinforcement time values (10, 20, 30, or 40 s), each of which was either in force for only a single session or for 3 sessions. Peak times were close to the time of reinforcement on the 20-s baseline and tracked the new reinforcement times both closely (but not exactly) and very rapidly. Peak time during transitions was affected by the criterion value in force on the previous session, exhibiting a proactive interference effect. Analysis of individual peak times during a session showed that transitions from lower to higher reinforcement time values were usually characterized by abrupt jumps in peak time, whereas descending transitions were mostly smooth but rapid. [less ▲]

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See detaill'application des dispositions pénales générales en matière bancaire et boursière
Flore, Daniel ULg

in Revue de Droit Commercial Belge [= RDC] = Tijdschrift voor Belgisch Handelsrecht [=TBH] (1997), 4

L'objectif est de dresser un cadre pénal général pour l'approche du droit pénal bancaire et boursier.

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See detailFibres alimentaires chez le chien : influence de l'incorporation de pulpes de betterave ou de chicorée sur la digestibilité des nutriments et les concentrations plasmatiques de plusieurs métabolites
Diez, Marianne ULg; Hornick, Jean-Luc ULg; Van Eenaeme, Christian ULg et al

in Revue de Médecine Vétérinaire (1997), 148

Cette étude relate les effets de la distribution de deux rations enrichies en pulpes de betterave ou de chicorée (7 p.100 ADF dans la matière sèche) en comparaison à une ration témoin sur les paramètres ... [more ▼]

Cette étude relate les effets de la distribution de deux rations enrichies en pulpes de betterave ou de chicorée (7 p.100 ADF dans la matière sèche) en comparaison à une ration témoin sur les paramètres fécaux, la digestibilité des principaux nutriments et plusieurs paramètres biochimiques (glucose, insuline, azote alpha-aminé, urée, cholestérol et triglycérides) mesurés à jeun ou pendant six heures après le repas chez huit chiens adultes en bonne santé. Les régimes enrichis en pulpes ont entraîné une augmentation significative de l'excrétion fécale totale, de l'excrétion de MS dans les matières fécales, une diminution de la teneur en MS des fèces ainsi qu'une diminution des coefficients de digestibilité des principaux nutriments. Le régime contenant la pulpe de betterave a entraîné une diminution de la glycémie à jeun, de l'insulinémie et des concentrations en triglycérides postprandiales, des concentrations en urée et en cholestérol mesurées avant et après le repas. Le régime contenant la pulpe de chicorée a provoqué une diminution de l'insulinémie postprandiale, des concentrations en urée et en cholestérol à jeun et après le repas. Ces deux types de pulpes, semblables par leur composition, induisent les mêmes types d'effets sur les paramètres fécaux et la digestibilité des nutriments, mais les effets systémiques sont plus importants lors de la distribution de pulpes de betterave. [less ▲]

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See detailRadiographical Assessment of Interphalangeal Rotation in the Evaluation of Equine Digital Conformation
Caudron, I.; Grulke, Sigrid ULg; Gabriel, Annick ULg et al

in Acta Anatomica (1997), 160(2), 95-9

This study is a part of a work to design a radiographical method to objectively define the conformation of an equine digit and to assess the individual appropriate trimming of a horse. Various angles were ... [more ▼]

This study is a part of a work to design a radiographical method to objectively define the conformation of an equine digit and to assess the individual appropriate trimming of a horse. Various angles were measured directly from the phalangeal bones. The authors observed that the bone relief of the sesamoid ligament insertions on the proximal phalanx was an essential landmark to determine the phalangeal alignment. The same angles were measured from specific radiographs and made it possible to quantify the rotation imposed to the proximal phalanx. The authors also noticed that the phalangeal rotation had little influence on the radiographic image of articular asymmetry. [less ▲]

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See detailThe Color Purple - les Blues Pourpres d'Alice Walker
Sacré, Robert ULg

in Les Cahiers du Jazz (1997), 12

Un livre (1982) - un film ( Steven Spielberg, 1985)

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