References of "Article"
     in
Bookmark and Share    
Full Text
See detailLa géométrie de la spatiocarte : corrections et validations, Spatiocartographie
Cornélis, Bernard; Billen, Roland ULg

in Bulletin de la Société Géographique de Liège (2000), (38(1)), 25-43

Detailed reference viewed: 36 (8 ULg)
Peer Reviewed
See detailTable of Ap and Am Stars in order of Variable-star Names II
Renson, Pierre ULg

in A Peculiar Newsletter (2000), 33

Detailed reference viewed: 18 (3 ULg)
Full Text
Peer Reviewed
See detailOsteoporose bij de bejaarde
Reginster, Jean-Yves ULg; Taquet, AN; Fraikin, G

in Medi-Sfeer (2000), 103

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailRespiration As The Main Determinant Of Carbon Balance In European Forests
Valentini, R.; Matteucci, G.; Dolman, Aj. et al

in Nature (2000), 404(6780),

Detailed reference viewed: 50 (4 ULg)
Peer Reviewed
See detailA novel messenger ribonucleic acid homologous to human MAGE-D is strongly expressed in rat Sertoli cells and weakly in Leydig cells and is regulated by follitropin, lutropin, and prolactin.
Hennuy, Benoît ULg; Reiter, E.; Cornet, Anne ULg et al

in Endocrinology (2000), 141(10), 3821-31

We have cloned a novel complementary DNA whose expression was decreased in rat Sertoli cell cultures after treatment with FSH. This complementary DNA encodes a protein of 570 amino acids and shares 92 ... [more ▼]

We have cloned a novel complementary DNA whose expression was decreased in rat Sertoli cell cultures after treatment with FSH. This complementary DNA encodes a protein of 570 amino acids and shares 92% homology with the human MAGE-D protein. In contrast to other MAGE genes (A, B, or C), we have shown that MAGE-D expression was ubiquitous in healthy rat tissues. In the seminiferous tubules, the MAGE-D was expressed in Sertoli cells but not in germ cells as demonstrated by RT-PCR and in situ hybridization, whereas for the other MAGE genes, expression has been shown to be restricted to germ cells. Interestingly, MAGE-D was also detected for the first time in the female gonad by Northern blotting. In MLTC-1 cells (mouse Leydig tumor cell line-1), LH and PRL stimulated MAGE-D expression. Using hypophysectomized rats, it was confirmed that FSH decreased MAGE-D expression, whereas LH and PRL increased MAGE-D messenger RNA level in the whole testis most probably through a direct action on Leydig cells. As MAGE-D is present in both the seminiferous compartment and interstitium and hormonally regulated in each, it is possible that it has specific functions in each compartment during the development and the maintenance of the testis. [less ▲]

Detailed reference viewed: 42 (6 ULg)
Full Text
Peer Reviewed
See detailA propos d'un cas de kératite à Acanthamoeba
Carrette, S.; Marechal-Courtois, C.; Hernandez, J. et al

in Bulletin de la Société Belge d'Ophtalmologie (2000), 275

CLINICAL REPORT: A clinical report of a contact lenses wearer with Acanthamoeba keratitis pointed out the diagnosis problem. The medical treatment is needed previously to any surgery. Finally the patient ... [more ▼]

CLINICAL REPORT: A clinical report of a contact lenses wearer with Acanthamoeba keratitis pointed out the diagnosis problem. The medical treatment is needed previously to any surgery. Finally the patient underwent enucleation. DISCUSSION: The authors are considering the microbiological aspects and laboratory techniques are described. CONCLUSION: For this very severe but hopefully rare pathology, the sooner the treatment the best. A therapeutic approach is described. [less ▲]

Detailed reference viewed: 139 (6 ULg)
Full Text
Peer Reviewed
See detailSkin Tensile Strength Modulation by Compressive Garments in Burn Patients. A Pilot Study
Fournier, R.; Pierard, Gérald ULg

in Journal of Medical Engineering & Technology (2000), 24(6, Nov-Dec), 277-80

Compression therapy is frequently used to prevent hypertrophy of post-burn scars. This pilot study was performed in 6 patients to assess non-invasive changes induced in the tensile strength of the skin ... [more ▼]

Compression therapy is frequently used to prevent hypertrophy of post-burn scars. This pilot study was performed in 6 patients to assess non-invasive changes induced in the tensile strength of the skin before any clinical improvement can be perceived. Assessments were performed using a computerized suction device delivering three 5 s cycles of 500 mbar depression. Measurements were made at one-month intervals for three months after initiating the garment compression therapy. Comparisons were made between the intact skin, the ungrafted and grafted post-burn scars and the graft donor sites. Data show that garment compression therapy alters the tensile strength in the skin of all test sites. The most reliable variations consist of an increase in both the extensibility and elasticity of the tissues submitted to traction. [less ▲]

Detailed reference viewed: 21 (0 ULg)
Full Text
Peer Reviewed
See detailThe branchial basket in Teleost feeding.
Vandewalle, Pierre ULg; Parmentier, Eric ULg; Chardon, Michel ULg

in Cybium (2000), 24(4), 319-342

In teleosts, feeding is effected principally by suction and food is handled by the branchial basket. Preys are carried to the oesophagus by the pharyngeal jaws (PJs). The pharyngobranchial bones ... [more ▼]

In teleosts, feeding is effected principally by suction and food is handled by the branchial basket. Preys are carried to the oesophagus by the pharyngeal jaws (PJs). The pharyngobranchial bones constitute the upper pharyngeal jaws (UPJs) and the 5th ceratobranchial bones, the lower pharyngeal jaws (LPJs). In lower teleosts, these jaws have well-separated spindly parts attached to the neurocranium, pectoral girdle, and hyoid bar; they only transport food and LPJ activity predominates. In acanthopterygians, the PJs become stronger, the left and right ceratobranchials fuse into one LPJ, and the pharyngobranchials join together to form two big UPJs articulating with the neurocranium. In labrids and scarids, the LPJ is also joined to the pectoral girdle. In acanthopterygians, a new retractor dorsalis muscle gives the UPJs the major role in food chewing and transport. Cypriniforms have developed original PJs with strong 5th ceratobranchials opposed to a postero-ventral neurocranial plate. Small-sized preys and food particles are seized by the gill rakers, small skeletal pieces supported by the branchial arches. [less ▲]

Detailed reference viewed: 175 (5 ULg)
Full Text
Peer Reviewed
See detailMechanics of the Respiratory System in Healthy Newborn Calves Using Impulse Oscillometry
Uystepruyst, Christophe; Reinhold, Petra; Coghe, Joost et al

in Research in Veterinary Science (2000), 68(1), 47-55

Arterial blood gases, acid-base balance and respiratory function tests using impulse oscillometry (IOS) were performed on 40 clinically healthy newborn calves during the first 24 hours of life to evaluate ... [more ▼]

Arterial blood gases, acid-base balance and respiratory function tests using impulse oscillometry (IOS) were performed on 40 clinically healthy newborn calves during the first 24 hours of life to evaluate their respiratory adaptation to extrauterine life. Gas exchange efficiency of the lung was significantly improved with time and was accompanied by the correction of the mixed acidosis observed at birth and by significant changes in respiratory mechanics. Major changes were detected within the first 6 hours. The significant decrease in resistance (R) and the increase in reactance (X) with time, demonstrate the improvement in respiratory mechanics of both upper and lower airways, and reflect the increase in lung volume, the improved lung tissue elasticity and/or distribution of the ventilation. Respiratory mechanical, arterial blood gases and acid-base balance data provided in this study describe a successful respiratory adaptation to extrauterine life in healthy newborn calves. [less ▲]

Detailed reference viewed: 29 (1 ULg)
Peer Reviewed
See detailConstructions and applications of wavelets in Sobolev spaces
Bastin, Françoise ULg

in Revista Ciencias Matematicas (2000), 18(2), 145-177

Detailed reference viewed: 33 (5 ULg)
Full Text
See detailDu chêne au tonneau
Jourez, Benoît ULg; Quin, Jean-Philippe

in Courrier du Bois (2000), 129

La tonnellerie, activité à la fois artisanale et industrielle, tire profit des plus beaux chênes. Si le mode de fabrication traditionnel du tonneau n'a pratiquement pas changé depuis son invention par les ... [more ▼]

La tonnellerie, activité à la fois artisanale et industrielle, tire profit des plus beaux chênes. Si le mode de fabrication traditionnel du tonneau n'a pratiquement pas changé depuis son invention par les Celtes il y a plus de 2000 ans, certains développements technologiques sont venus aider les artisans dans leur travail quotidien. Parallèlement, le progrès des connaissances dans les sciences du bois, de la chimie et de la microbiologie nous ont appris à quel point l'élevage du vin en fûts de chêne reste une étape essentielle dans la maturation de ce liquide sacré. [less ▲]

Detailed reference viewed: 30 (3 ULg)
Full Text
Peer Reviewed
See detailSimulation of first and second order scattering by rough surfaces with a sound ray formalism
Embrechts, Jean-Jacques ULg

in Journal of Sound & Vibration (2000), 229(1)

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailRelative Accuracy of the Identification of Ovarian Structures in the Cow by Ultrasonography and Palpation Per Rectum
Hanzen, Christian ULg; Pieterse, M.; Szenci, Otto et al

in Veterinary Journal (2000), 159(2), 161-170

Manual palpation or ultrasonographic examination of the cow's genital tract are currently used by veterinarians involved in reproductive management, but knowledge of the potential and the limitations of ... [more ▼]

Manual palpation or ultrasonographic examination of the cow's genital tract are currently used by veterinarians involved in reproductive management, but knowledge of the potential and the limitations of both methods is important to obtain an optimal accuracy in the diagnosis of physiological and pathological ovarian structures. This review presents the main features of manual and ultrasonographic characteristics of follicles, corpora lutea (with or without a cavity), follicular and lutenized cysts and the reliability of the two methods is compared. Manual diagnosis of follicles <10 mm is rather inaccurate, but ultrasound offers the possibility to diagnose follicles <5 mm and to measure their inner diameter. The predictive values of the presence or absence of a corpus luteum as determined by palpation are similar (78 vs. 75%). Manual or ultrasonographic diagnosis of the growing or regressing corpus luteum is rather difficult. The positive predictive value of a mature corpus luteum diagnosed by ultrasonography is lower (87%) than the negative predictive value (92%). Compared to manual palpation, ultrasonography permits a better estimation of the number and to determine more precisely the size of the mature corpus luteum. The positive values for follicular cysts diagnosed by palpation or by ultrasonography are 66 and 74% respectively, and for luteal cysts, the values are 66 and 85%, respectively. Manual palpation or ultrasonography are useful tools to diagnose ovarian structures in the cow. The accuracy of such methods can be enhanced by securing information on the reproductive history of the animal, palpation of uterine horns, vaginal examination or progesterone determinations. [less ▲]

Detailed reference viewed: 52 (5 ULg)
Full Text
Peer Reviewed
See detailDoppler ultrasonography and single-fiber laser Doppler flowmetry for measurement of hind limb blood flow in anesthetized horses
Raisis, Anthea L; Young, Lesley E; Taylor, Polly M et al

in American Journal of Veterinary Research (2000), 61(3), 286-290

OBJECTIVE: To use Doppler ultrasonography and single-fiber laser Doppler flowmetry (LDF) to evaluate blood flow in the dependent and nondependent hind limbs of anesthetized horses and to evaluate changes ... [more ▼]

OBJECTIVE: To use Doppler ultrasonography and single-fiber laser Doppler flowmetry (LDF) to evaluate blood flow in the dependent and nondependent hind limbs of anesthetized horses and to evaluate changes in femoral arterial blood flow and microvascular skeletal muscle perfusion in response to administration of phenylephrine hydrochloride or dobutamine hydrochloride. ANIMALS: 6 healthy adult horses. PROCEDURE: Horses were anesthetized and positioned in left lateral recumbency. Doppler ultrasonography was used to measure velocity and volumetric flow in the femoral vessels. Single-fiber LDF was used to measure relative microvascular perfusion at a single site in the semimembranosus muscles. Phenylephrine or dobutamine was then administered to decrease or increase femoral arterial blood flow, and changes in blood flow and microvascular perfusion were recorded. RESULTS: Administration of phenylephrine resulted in significant decreases in femoral arterial and venous blood flows and cardiac output and significant increases in mean aortic blood pressure, systemic vascular resistance, and PCV. Administration of dobutamine resulted in significant increases in femoral arterial blood flow, mean aortic blood pressure, and PCV. Significant changes in microvascular perfusion were not detected. CONCLUSION AND CLINICAL RELEVANCE: Results suggest that Doppler ultrasonography and single-fiber LDF can be used to study blood flows in the hind limbs of anesthetized horses. However, further studies are required to determine why changes in femoral arterial blood flows were not associated with changes in microvascular perfusion [less ▲]

Detailed reference viewed: 31 (1 ULg)
Peer Reviewed
See detailEffects of glucocorticoids on hepatic sensitivity to insulin and glucagon in man.
Dirlewanger, M.; Schneiter, P. H.; Paquot, Nicolas ULg et al

in Clinical Nutrition (2000), 19(1), 29-34

AIMS: This study was undertaken to determine the effects of a short-term dexamethasone treatment on hepatic sensitivities to insulin and glucagon. METHODS: Eleven healthy subjects were studied during one ... [more ▼]

AIMS: This study was undertaken to determine the effects of a short-term dexamethasone treatment on hepatic sensitivities to insulin and glucagon. METHODS: Eleven healthy subjects were studied during one or several of four protocols. In all protocols, somatostatin was infused continuously to inhibit pancreatic hormone secretion. In protocol 1, basal insulin was infused over 300 min while glucagon was infused at a rate of 0.5 mg/kg(-1)/min(-1)during 180 min, then at a rate of 1.5 ng/kg(-1)/min(-1)during 150 min. In protocol 2, the same experiment was performed after a 2 day treatment with 8 mg/day dexamethasone. In protocol 3, the two-step glucagon infusion was performed during insulin infusion at a rate aimed to reproduce the hyperinsulinemia observed during protocol 2. In protocol 4, continuous basal insulin and low glucagon (0.5 mg/kg(-1)/min(-1)) were infused over 330 min. RESULTS: In protocol 1, plasma glucose rose transiently by 2.0 +/- 0.3 mmol/l when the glucagon rate was increased and glucose production increased by 1.4 +/- 0.5 micromol/kg(-1)/min(-1). In protocol 2, the insulin infusion rate (1.85 +/- 0.36 nmol/kg(-1)/min(-1)) required to maintain glycemia was 3.3-fold higher than during protocol 1. Glucagon-induced stimulation of glycemia (by 1.47 +/- 0.5 mmol/l) and endogenous glucose production (by 0.8 +/- 0.3 micromol/kg(-1)/min(-1)) were blunted, but not abolished. In protocol 3, endogenous glucose production was suppressed by 75% by hyperinsulinemia and was not stimulated when the glucagon infusion rate was increased. In protocol 4, endogenous glucose production did not change significantly with time. CONCLUSION: These results indicate that high dose glucocorticoids induce a marked hepatic insulin resistance. Stimulation of glucose production by hyperglucagonemia was maintained in spite of hyperinsulinemia which can be attributed to either hepatic insulin resistance and/or increased hepatic glucagon sensitivity. [less ▲]

Detailed reference viewed: 15 (2 ULg)
See detailGuerres au Congo (1996-1999), acteurs et scénarios
Kabamba, Bob ULg

in cahiers du CEDAF (2000)

Detailed reference viewed: 17 (2 ULg)
Full Text
Peer Reviewed
See detailPathophysiology of a fall in arterial oxygen saturation during sputum induction.
Cataldo, Didier ULg

in CHEST (2000), 117(6), 1818-9

Detailed reference viewed: 33 (0 ULg)
Peer Reviewed
See detailDynamics and three-dimensional localization of ribosomal RNA within the nucleolus.
Thiry, Marc ULg; Cheutin, T.; O'Donohue, M. F. et al

in RNA (New York, N.Y.) (2000), 6(12), 1750-61

Although rRNA synthesis, maturation, and assembly into preribosomal particles occur within the nucleolus, the route taken by pre-rRNAs from their synthetic sites toward the cytoplasm remains largely ... [more ▼]

Although rRNA synthesis, maturation, and assembly into preribosomal particles occur within the nucleolus, the route taken by pre-rRNAs from their synthetic sites toward the cytoplasm remains largely unexplored. Here, we employed a nondestructive method for the incorporation of BrUTP into the RNA of living cells. By using pulse-chase experiments, three-dimensional image reconstructions of confocal optical sections, and electron microscopy analysis of ultrathin sections, we were able to describe topological and spatial dynamics of rRNAs within the nucleolus. We identified the precise location and the volumic organization of four typical subdomains, in which rRNAs are successively moving towards the nucleolar periphery during their synthesis and processing steps. The incorporation of BrUTP takes place simultaneously within several tiny spheres, centered on the fibrillar centers. Then, the structures containing the newly synthesized RNAs enlarge and appear as compact ringlets disposed around the fibrillar centers. Later, they form hollow spheres surrounding the latter components and begin to fuse together. Finally, these structures widen and form large rings reaching the limits of the nucleoli. These results clearly show that the transport of pre-rRNAs within the nucleolus does not occur randomly, but appears as a radial flow starting from the fibrillar centers that form concentric rings, which finally fuse together as they progress toward the nucleolar periphery. [less ▲]

Detailed reference viewed: 14 (2 ULg)
Full Text
Peer Reviewed
See detailSynovial fluid matrix metalloproteinase-3 levels are increased in inflammatory arthritides whether erosive or not
Ribbens, Clio ULg; Andre, Béatrice ULg; Kaye, O. et al

in Rheumatology (2000), 39(12), 1357-1365

OBJECTIVE: To study the levels of matrix metalloproteinase-3 (MMP-3) in the knee synovial fluid (SF) of inflammatory arthropathies (rheumatoid arthritis whether erosive or not, reactive arthritis, acute ... [more ▼]

OBJECTIVE: To study the levels of matrix metalloproteinase-3 (MMP-3) in the knee synovial fluid (SF) of inflammatory arthropathies (rheumatoid arthritis whether erosive or not, reactive arthritis, acute crystal arthritis) and degenerative arthropathies [chronic crystal disease, osteoarthritis and (control) meniscus pathology] and to correlate them with the degree of joint destruction, local inflammatory and immune parameters and systemic markers of inflammation. METHODS: SF levels of MMP-3 (precursor, active and tissue inhibitor of MMP-bound forms), tumour necrosis factor (TNF) alpha, soluble TNF receptors I and II, interleukin (IL)-6 and soluble IL-6 receptor were measured by ELISA in 107 inflammatory and 53 degenerative arthropathies. RESULTS: MMP-3 levels in SF were (i) significantly higher in inflammatory than in degenerative arthropathies; (ii) not related to the degree of joint destruction; (iii) significantly correlated with the levels of all SF markers tested and with erythrocyte sedimentation rate and serum levels of C-reactive protein and fibrinogen. CONCLUSION: Increased MMP-3 levels in SF are found in inflammatory arthropathies and are not specific for erosive joint diseases. MMP-3 in SF is therefore a potential candidate for the assessment of the inflammatory process in joints. However, the exclusive determination of the active form could indicate the degree of joint destruction. [less ▲]

Detailed reference viewed: 19 (3 ULg)
Full Text
Peer Reviewed
See detailERK activation upon hypoxia: involvement in HIF-1 activation.
Minet, E.; Arnould, T.; Michel, G. et al

in FEBS Letters (2000), 468(1), 53-8

Hypoxia-inducible factor-1 (HIF-1) is a transcription factor activated by hypoxia. The HIF-1 activation transduction pathway is poorly understood. In this report, we investigated the activation of ... [more ▼]

Hypoxia-inducible factor-1 (HIF-1) is a transcription factor activated by hypoxia. The HIF-1 activation transduction pathway is poorly understood. In this report, we investigated the activation of extracellular regulated kinases (ERK) in hypoxia and their involvement in HIF-1 activation. We demonstrated that in human microvascular endothelial cells-1 (HMEC-1), ERK kinases are activated during hypoxia. Using dominant negative mutants, we showed that ERK1 is needed for hypoxia-induced HIF-1 transactivation activity. Moreover, using a kinase assay and Western blot experiments, we showed that HIF-1alpha is phosphorylated in hypoxia by an ERK-dependent pathway. These results evidence the role of mitogen-activated protein kinase in the transcriptional response to hypoxia. [less ▲]

Detailed reference viewed: 32 (3 ULg)
Peer Reviewed
See detailMri Guided Percutaneous Abdominal Biopsy in a Closed Magnet: Assessment in an Animal Study
Fanchamps, J. M.; Kos, X.; Snaps, Frédéric ULg et al

in JBR-BTR : Journal Belge de Radiologie - Belgisch Tijdschrift voor Radiologie (2000), 83(4), 149-52

MRI guided percutaneous abdominal biopsy was evaluated in an animal model, using a closed magnet and different types of needles. Thirty-six single pass biopsies were performed in 6 piglets with 6 types of ... [more ▼]

MRI guided percutaneous abdominal biopsy was evaluated in an animal model, using a closed magnet and different types of needles. Thirty-six single pass biopsies were performed in 6 piglets with 6 types of MR compatible needles. Virtual targets of a diameter of 2 cm were drawn on the images of the right and left lobe of the liver and the upper and lower poles of both kidneys. FMPSPGR sequences were applied during an apnea of 19 to 23 seconds in axial, sagittal, coronal or axial oblique planes using a closed 1.0 T magnet and the body coil. Piglets were autopsied 1 hour after the procedure. Mean duration of the procedure was 16.9 (11-37) minutes; mean number of acquisitions per procedure was 5.9 (3-12); mean number of redirections of the needle was 0.6 (0-4). Pathological samples from the liver and kidneys of good quality were obtained in 22/36 (72.2%) cases. A subcapsular hematoma was observed in 18/24 (75.0%) cases of renal biopsies and in 1/12 (8.3%) of hepatic biopsies. No statistically significant correlation could be established between duration of the procedure and site of biopsy and between the type of biopsy needle and complication (p = 0.18 to 0.85). In conclusion, MRI guided percutaneous needle biopsy in the abdomen is a reliable technique in piglets using a closed magnet. [less ▲]

Detailed reference viewed: 21 (0 ULg)
Peer Reviewed
See detailTransition rates of the resonance line doublet in the Cl I sequence, Ar II to Ge XVI
Biémont, Emile ULg; Träbert, E.

in Journal of Physics : B Atomic Molecular & Optical Physics (2000), 33

Detailed reference viewed: 8 (2 ULg)
Full Text
Peer Reviewed
See detailLinear growth and final height after treatment for Cushing's disease in childhood.
LEBRETHON, Marie-Christine ULg; Grossman, A. B.; Afshar, F. et al

in The Journal of clinical endocrinology and metabolism (2000), 85(9), 3262-5

Cushing's disease is associated with growth failure in childhood and adolescence. Growth and final height were analyzed in 10 patients who were cured or in remission after treatment of Cushing's disease ... [more ▼]

Cushing's disease is associated with growth failure in childhood and adolescence. Growth and final height were analyzed in 10 patients who were cured or in remission after treatment of Cushing's disease. Seven males and 3 females, aged 6.8-17.6 yr (bone age, 3.3-15.4 yr), had transsphenoidal surgery, which was combined with pituitary irradiation (4,500 cGy in 25 fractions) in 5 patients. At presentation, 5 patients were prepubertal (males), and 5 were pubertal (2 males and 3 females). The mean height SD score was -2.15 +/-1.26 (range, -0.21 to -4.32) compared with mean target height SD score of -0.43 +/- 0.58. Height velocity in 6 patients was subnormal (0.9-3.8 cm/yr). After treatment, short-term height velocity, over a mean interval of 0.57 yr, in 8 patients not receiving human GH (hGH) therapy, was variable (range, 0.8-7.6 cm/yr). GH stimulation tests (insulin tolerance test/glucagon) in 9 subjects showed peak GH levels of 0.5-20.9 mU/L. Eight were treated with hGH (14 IU/m2 wk), combined in 2 girls and 1 boy with a GnRH analog. After 1 yr of hGH, the mean height SD score had increased from -2.45 +/- 1.0 at initiation of hGH to -2.07 +/- 1.2 (P = 0.01). GH therapy was continued until final height or latest assessment. The mean final height SD score (n = 6) was - 1.24 +/- 1.38, and at the latest assessment the mean height SD score (n = 4) was - 1.52 +/- 1.33. Combining these 2 groups, the mean height so score was -1.36 +/- 1.29. The difference between final or latest height SD score and target height SD score was 0.93 +/- 1.13, i.e. less (P = 0.005) than the difference between height and target height SD score of 1.72 +/- 1.26 at presentation. In conclusion, catch-up and favorable long-term growth was seen after treatment for Cushing's disease. Posttreatment GH deficiency was frequent, and early hGH replacement may have contributed to the encouraging outcome. [less ▲]

Detailed reference viewed: 7 (0 ULg)
See detailEclipse totale du 11 août 1999 et évolution de la basse ionosphère
Delcourt, J. J.; Jodogne, J.-C.; Biémont, Emile ULg

in Ciel et Terre (2000), 116(1), 6-7

Detailed reference viewed: 8 (1 ULg)
Full Text
Peer Reviewed
See detailHartree-Fock instabilities and electronic properties
Dehareng, Dominique ULg; Dive, Georges ULg

in Journal of Computational Chemistry (2000), 21(6), 483-504

Hartree-Fock instabilities are investigated for about 80 compounds, from acetylene to mivazerol (27 atoms) and a cluster of 18 water molecules, within a double zeta basis set. For most conjugated systems ... [more ▼]

Hartree-Fock instabilities are investigated for about 80 compounds, from acetylene to mivazerol (27 atoms) and a cluster of 18 water molecules, within a double zeta basis set. For most conjugated systems, the restricted Hartree-Fock wave function of the singlet fundamental state presents an external or so-called triplet instability. This behavior is studied in relation with the electronic correlation, the vicinity of the triplet and singlet excited states, the electronic delocalization linked with resonance, the nature of eventual heteroatoms, and the size of the systems. The case of antiaromatic systems is different, because they may present a very large internal Hartree-Fock instability. Furthermore, the violation of Hund's rule, observed for these compounds, is put in relation with the fact that the high symmetry structure in its singlet state has no feature of a diradical-like species. It appears that the triplet Hartree-Fock instability is directly related with the spin properties of nonnull orbital angular momentum electronic systems. (C) 2000 John Wiley & Sons, Inc. [less ▲]

Detailed reference viewed: 33 (3 ULg)
Full Text
Peer Reviewed
See detailComment utiliser l'hypnose en anesthésie
Faymonville, Marie ULg; Joris, Jean ULg; Lamy, Maurice ULg

in Praticien en Anesthésie Réanimation (Le) (2000), 4(6), 345-348

Detailed reference viewed: 226 (8 ULg)
Peer Reviewed
See detailPerturbed Proximal Point Algorithm with Nonquadratic Kernel
Brohé, Myrana; Tossings, Patricia ULg

in Serdica Mathematical Journal (2000), 26

Let H be a real Hilbert space and T be a maximal monotone operator on H. A well-known algorithm, developed by R.T. Rockafellar, for solving the problem "To find x in H such that 0 in Tx" is the proximal ... [more ▼]

Let H be a real Hilbert space and T be a maximal monotone operator on H. A well-known algorithm, developed by R.T. Rockafellar, for solving the problem "To find x in H such that 0 in Tx" is the proximal point algorithm. Several genaralizations have been considered by several authors: introduction of a perturbation, introduction of a variable metric in the perturbed algorithm, introduction of a pseudo-metric in place of the classical regularization, ... We summarize some of these extensions by taking into account a pseudo-metric as regularization and a perturbation in an inexact version of the algorithm. [less ▲]

Detailed reference viewed: 25 (1 ULg)
Full Text
Peer Reviewed
See detailLa douleur pelvienne chez le patient oncologique
Jansen, Nicolas ULg; Nickers, Philippe ULg; Devoghel, Jean-Claude ULg

in Oncologie (2000), 2(4), 187-200

Pelvic pain is a common problem in the general population. In cancer patients this pain can be secondary to tumor activity or recent tumor related interventions (surgery, radiotherapy, chemotherapy). On ... [more ▼]

Pelvic pain is a common problem in the general population. In cancer patients this pain can be secondary to tumor activity or recent tumor related interventions (surgery, radiotherapy, chemotherapy). On the other hand cancer patients can also suffer from not cancer related pain. Cancer related pain is often chronic. Whatever the cause of this pain, an important psychological factor is often present, if not attributing to the pathogenesis of the pain, then as an secondary effect from the pain. Managing pelvic pain requires knowledge of the regional anatomy. A general overview is given of the approach to an oncological patient presenting with pelvic pain. Three different possibilities are discussed: (1) pain in a patient without a presently known pelvic or abdominal malignancy, (2) pain in a patient treated recently for a tumor in the pelvic area or lower abdomen, (3) pain in an so far untreated patient with a known tumor. Finally an overview of treatment options is presented. [less ▲]

Detailed reference viewed: 170 (5 ULg)
Full Text
Peer Reviewed
See detailStructure-activity relationships on adrenoceptors and imidazoline-preferring binding sites (I(1,2)-PBSs). Part 1: Weak intramolecular H-bond and conformational flexibility in a new I1-PBS-selective imidazoline analogue, trans1-(4',5'-dihydro-1'H-imidazol-2'-yl)methyl-2-hydroxyindane (PMS 952).
Ye, Hai Fen; Dive, Georges ULg; Dehareng, Dominique ULg et al

in Bioorganic & Medicinal Chemistry (2000), 8(8), 1861-9

The highly selective I1-PBS imidazoline analogue PMS 952 has been selected to study the incidence of intramolecular hydrogen bond and molecular flexibility on its biological activity. On one hand, the ... [more ▼]

The highly selective I1-PBS imidazoline analogue PMS 952 has been selected to study the incidence of intramolecular hydrogen bond and molecular flexibility on its biological activity. On one hand, the weak energy difference between three calculated conformers does not support the stabilization of one conformer by an internal hydrogen bond. The 3-D electrostatic map confirms this feature and the solvent effect does not significantly modify the relative energy of these conformers. On the other hand, the conformational spaces of the neutral and ionized forms present a great number of equilibrium structures, in a short energetic range (20 Kcal). The results are representative of an exceptional conformational flexibility due to a cooperative effect between several parts of the molecule. [less ▲]

Detailed reference viewed: 83 (1 ULg)
Full Text
Peer Reviewed
See detailAuditory processing in the vegetative state.
Laureys, Steven ULg; Faymonville, Marie ULg; Degueldre, Christian ULg et al

in Brain : A Journal of Neurology (2000), 123 ( Pt 8)

H(2)(15)O-PET was used to investigate changes in regional cerebral blood flow in response to auditory stimulation in patients in the vegetative state. Five patients in a vegetative state of hypoxic origin ... [more ▼]

H(2)(15)O-PET was used to investigate changes in regional cerebral blood flow in response to auditory stimulation in patients in the vegetative state. Five patients in a vegetative state of hypoxic origin were compared with 18 age-matched controls. In addition, the cerebral metabolism of these patients and 53 age-matched controls was studied using [(18)F]fluorodeoxyglucose. In control subjects, auditory click stimuli activated bilateral auditory cortices [Brodmann areas (BA) 41 and 42] and the contralateral auditory association cortices (BA 22). In the patients, although resting metabolism was decreased to 61% of normal values, bilateral auditory areas 41 and 42 showed activation as seen in the controls, but the temporoparietal junction cortex (BA 22) failed to be activated. Moreover, the auditory association cortex was functionally disconnected from the posterior parietal association area (BA 40), the anterior cingulate cortex (BA 24) and the hippocampus, as revealed by psychophysiological interaction analysis. Thus, despite altered resting metabolism, the auditory primary cortices were still activated during external stimulation, whereas hierarchically higher-order multi- modal association areas were not. Such a cascade of functional disconnections along the auditory cortical pathways, from the primary auditory areas to multimodal and limbic areas, suggests that the residual cortical processing observed in the vegetative state cannot lead to the integrative processes that are thought to be necessary for the attainment of the normal level of awareness. [less ▲]

Detailed reference viewed: 45 (7 ULg)
Peer Reviewed
See detailRandomized comparison of intranasal and transdermal estradiol.
Lopes, P.; Merkus, H. M.; Nauman, J. et al

in Obstetrics & Gynecology (2000), 96(6), 906-12

To compare the efficacy and patient acceptability of intranasal versus transdermal 17 beta-estradiol (E2) delivery systems for postmenopausal symptoms. METHODS: Postmenopausal women were randomly assigned ... [more ▼]

To compare the efficacy and patient acceptability of intranasal versus transdermal 17 beta-estradiol (E2) delivery systems for postmenopausal symptoms. METHODS: Postmenopausal women were randomly assigned to intranasal 17 beta-E2, 300 microg daily (n = 176) or transdermal 17 beta-E2 (delivering 50 microg/day), two patches per week (n = 185) for 12 weeks, followed by a 4-week period with the alternate treatment. Efficacy was compared between groups using the Kupperman Index and vasomotor symptoms at week 12. Patient acceptability was compared by patient choice of administration route and by questionnaire at week 16. RESULTS: Intranasal and transdermal therapy produced significant reductions in the Kupperman Index and in the occurrence of hot flushes and night sweats at week 12. Alleviation of climacteric symptoms was statistically equivalent in the two treatment groups (P <.001). The difference between groups in the Kupperman Index score of -0.5 +/- 0.9 (95% confidence interval -2.3, 1.3) was within the predetermined interval of equivalence. Both therapies were well tolerated with similar adverse event rates, except for moderate and severe mastalgia which was significantly less frequent with intranasal E2 (7.2%) than with the patch (15.5%, P =.02). Sixty-six percent of patients chose to continue the intranasal therapy and 34% the transdermal therapy (P <.001). Satisfaction was greater with intranasal therapy at week 16 (P <.001). CONCLUSION: Intranasal and transdermal estrogen delivery systems had equivalent efficacy and similar safety profiles. Intranasal therapy was the patients' choice for long-term treatment. [less ▲]

Detailed reference viewed: 5 (0 ULg)
Full Text
Peer Reviewed
See detailDo estrogens effectively prevent osteoporosis-related fractures?
Reginster, Jean-Yves ULg; Bruyère, Olivier ULg; Audan, M. et al

in Calcified Tissue International (2000), 67

Detailed reference viewed: 14 (6 ULg)
Peer Reviewed
See detailEndocardite végétante dans l’espèce équine : revue de littérature à partir de 2 cas cliniques
Amory, Hélène ULg; Christmann, U.; Cassart, Dominique ULg et al

in Annales de Médecine Vétérinaire (2000), 144

Detailed reference viewed: 52 (3 ULg)
Peer Reviewed
See detailLaparoscopic treatment of endometriomas: cystectomy or suppression? Against laparoscopic cystectomy
Squifflet, Jean; NISOLLE, Michelle ULg; Donnez, Jacques

in Gynécologie Obstétrique & Fertilité (2000), 28(7-8), 586-7

Detailed reference viewed: 7 (0 ULg)
Peer Reviewed
See detailPLAG1, the main translocation target in pleomorphic adenoma of the salivary glands, is a positive regulator of IGF-II.
Voz, Marianne ULg; Agten, N. S.; Van de Ven, W. J. et al

in Cancer Research (2000), 60(1), 106-13

PLAG1, a novel developmentally regulated C2H2 zinc finger gene, is consistently rearranged and overexpressed in pleomorphic adenomas of the salivary glands with 8q12 translocations. In this report, we ... [more ▼]

PLAG1, a novel developmentally regulated C2H2 zinc finger gene, is consistently rearranged and overexpressed in pleomorphic adenomas of the salivary glands with 8q12 translocations. In this report, we show that PLAG1 is a nuclear protein that binds DNA in a specific manner. The consensus PLAG1 binding site is a bipartite element containing a core sequence, GRGGC, and a G-cluster, RGGK, separated by seven random nucleotides. DNA binding is mediated mainly via three of the seven zinc fingers, with fingers 6 and 7 interacting with the core and finger 3 with the G-cluster. In transient transactivation assays, PLAG1 specifically activates transcription from its consensus DNA binding site, indicating that PLAG1 is a genuine transcription factor. Potential PLAG1 binding sites were found in the promoter 3 of the human insulin-like growth factor II (IGF-II) gene. We show that PLAG1 binds IGF-II promoter 3 and stimulates its activity. Moreover, IGF-II transcripts derived from the P3 promoter are highly expressed in salivary gland adenomas overexpressing PLAG1. In contrast, they are not detectable in adenomas without abnormal PLAG1 expression nor in normal salivary gland tissue. This indicates a perfect correlation between PLAG1 and IGF-II expression. All of these results strongly suggest that IGF-II is one of the PLAG1 target genes, providing us with the first clue for understanding the role of PLAG1 in salivary gland tumor development. [less ▲]

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailImpact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: a free-response ROC analysis.
Hustinx, Roland ULg; Dolin, R. J.; Benard, F. et al

in European Journal of Nuclear Medicine (2000), 27(9), 1365-71

The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating ... [more ▼]

The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating characteristic (FROC) methodology. Thirty-four patients with various abdominal tumors were evaluated (11 men, 23 women, median age 48 years). Whole-body emission scans were performed 68 min (35-102 min) after intravenous injection of 4.3 MBq/kg fluorine-18 fluorodeoxyglucose (FDG). Images were reconstructed using the OS-EM algorithm and corrected for attenuation either using postinjection singles transmission (n=27) or by calculation and body outline (n=7). Total scan duration did not exceed 70 min. Studies were read independently by four observers unaware of any clinical data. The uncorrected (UC) images were systematically read before the attenuation-corrected (AC) images. All studies were given an image quality score ranging from 1 (unreadable) to 5 (excellent). Each focus of increased activity was then localized and given a probability of malignancy using a five-point scale. The average image quality score was similar for both UC and AC images. At the time of the positron emission tomography (PET) scans, 127 lesions (63 liver metastases, 9 retroperitoneal lesions, 50 peritoneal or bowel lesions, and 5 pancreatic carcinomas) were revealed by pathological or correlative studies. The areas under the FROC curves were consistently greater for AC images (range 0.8663-0.8867) than for UC images (range 0.7774 -0.8613). Overall, the difference between the AC images and the UC images was significant (P=0.019). In particular, correction for attenuation increased the sensitivity regardless of the location of the lesions. In conclusion, correction for attenuation significantly improves the diagnostic accuracy of FDG-PET for abdominal staging of neoplasms, without impairing the image quality. [less ▲]

Detailed reference viewed: 18 (2 ULg)
Full Text
Peer Reviewed
See detailLa progression au sein de la narration en égyptien: Éléments d’une grammaire du texte
Winand, Jean ULg

in Bulletin de l’Institut Français d’Archéologie Orientale (2000), (100), 403-435

Detailed reference viewed: 89 (4 ULg)
Peer Reviewed
See detailInfo-congres. L'etude "MIRACL" ou "Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering".
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(12), 1064-6

The results of the "MIRACL" trial ("Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering") were presented at the recent annual meeting of the American Heart Association in New Orleans last ... [more ▼]

The results of the "MIRACL" trial ("Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering") were presented at the recent annual meeting of the American Heart Association in New Orleans last November 2000. This study demonstrates that atorvastatin, at a daily dose of 80 mg starting within the first 24 to 96 hours after an acute coronary event (unstable angina or non-Q-wave acute myocardial infarction) and maintained for 4 months, improves the cardiovascular prognosis by decreasing the combined risk of death (any cause), nonfatal myocardial infarction, resuscitated cardiac arrest and worsening angina with new objective evidence of ischemia requiring urgent hospitalization (-16% versus placebo, p < 0.05). [less ▲]

Detailed reference viewed: 59 (2 ULg)
Full Text
Peer Reviewed
See detailNerve biopsy: indications and contribution to the diagnosis of peripheral neuropathy. The experience of the Born Bunge Foundation University of Antwerp and University of Liege between 1987 and 1997.
Deprez, Manuel ULg; Ceuterick-de Groote, C.; Schoenen, Jean ULg et al

in Acta Neurologica Belgica (2000), 100(3), 162-6

We reviewed 355 nerve biopsies analysed at the Laboratories of Neuropathology of the Born-Bunge Foundation/University of Antwerp (BBF/UIA) and University of Liege (ULg) between 1987 and 1997. We examined ... [more ▼]

We reviewed 355 nerve biopsies analysed at the Laboratories of Neuropathology of the Born-Bunge Foundation/University of Antwerp (BBF/UIA) and University of Liege (ULg) between 1987 and 1997. We examined the indications for nerve biopsy, the yield of the procedure, and the influence of clinical and neuropathological parameters. Contributory biopsies accounted for 35.5% and 47.3% respectively at ULg and BBF/UIA laboratories: of these, one third showed specific histological findings, the majority being informative only when combined with the relevant clinical data. The profile of indications for nerve biopsy was roughly comparable in both laboratories. The search for an inflammatory neuropathy prompted 35-40% of all biopsies with more than 50% of specimens being informative in this indication. The lowest yield (20%) was obtained among the nerve biopsies performed in the absence of any presumptive aetiology. These accounted for 22-33% of all cases. Inadequate surgical resection, delays in transport or processing errors precluded histological study of 4% (BBF/UIA) to 8% (ULg) of the specimens. We conclude that nerve biopsies should be performed by experienced surgeons and handled in specialised laboratories. Only a relatively small number of causes of neuropathy can be diagnosed on the basis of histology alone. More often, contributory biopsies will result from the combination of non-specific suggestive histological features with relevant clinical information. The diagnostic yield of nerve biopsy is function of careful patient selection and close collaboration between the clinician and the neuropathologist. [less ▲]

Detailed reference viewed: 56 (4 ULg)
Peer Reviewed
See detailQuelques considerations generales et rappels historiques a propos de la therapeutique.
Kulbertus, Henri ULg; Scheen, André ULg

in Revue Médicale de Liège (2000), 55(4), 201-5

Detailed reference viewed: 34 (2 ULg)
See detail1re campagne de fouille à Chagar Bazar (Syrie)
Tunca, Önhan ULg; McMahon, A.; Baghdo, Abd el-Massih

in Orient-Express 2000/1 (2000)

Detailed reference viewed: 66 (18 ULg)
Peer Reviewed
See detailGelling properties of whey proteins after enzymic fat hydrolysis
Blecker, Christophe ULg; Paquot, Michel ULg; Deroanne, C.

in Journal of Food Science (2000), 65(4), 561-563

The effect of residual fat hydrolysis upon the gelation of whey protein concentrate (WPC) was studied. Gelling properties of a commercial WPC and lipase-treated WPC were evaluated on the basis of least ... [more ▼]

The effect of residual fat hydrolysis upon the gelation of whey protein concentrate (WPC) was studied. Gelling properties of a commercial WPC and lipase-treated WPC were evaluated on the basis of least concentration endpoint gelation, penetration test, texture profile analysis and water-holding capacity. Heat treatment of lipase-treated WPC led to gels with the highest hardness, springiness, cohesiveness and water retention. Such transformed WPC could be advantageously used to help improve texture in formulated meat, bakery, and confectionery products. [less ▲]

Detailed reference viewed: 17 (5 ULg)
Full Text
Peer Reviewed
See detailConvenient Genotyping of Six Myostatin Mutations Causing Double-Muscling in Cattle Using a Multiplex Oligonucleotide Ligation Assay
Karim, Latifa ULg; Coppieters, Wouter ULg; Grobet, Luc ULg et al

in Animal Genetics (2000), 31(6), 396-9

We herein describe a procedure that allows for simultaneous genotyping of six loss-of-function mutations in the bovine myostatin gene associated with the double-muscling phenotype. The proposed method ... [more ▼]

We herein describe a procedure that allows for simultaneous genotyping of six loss-of-function mutations in the bovine myostatin gene associated with the double-muscling phenotype. The proposed method relies on a multiplex oligonucleotide ligation assay and detection of the fluorescently labelled products using automatic sequencers. [less ▲]

Detailed reference viewed: 53 (10 ULg)
Peer Reviewed
See detailPharma-clinics. Le medicament du mois. Le glimepiride (Amarylle).
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(3), 184-6

Glimepiride, commercialized in Belgium under the trade name of Amarylle by Aventis, is a new sulphonylurea compound which is indicated in the treatment of type 2 diabetes, after diet and exercise failure ... [more ▼]

Glimepiride, commercialized in Belgium under the trade name of Amarylle by Aventis, is a new sulphonylurea compound which is indicated in the treatment of type 2 diabetes, after diet and exercise failure. It is available as 2 mg tablets. The initial doses is 1 mg, to be progressively increased up to 4 mg per day, if necessary, with a maximal daily dose of 6 mg. It is recommended to take glimepiride once a day, with the first main meal. Because of a particular binding of this sulphonylurea to the B cells of Langerhans pancreatic islets and, perhaps, of the presence of some extrapancreatic effects, both hypoglycaemic risk and circulating plasma insulin levels are lower with glimepiride than with glibenclamide, the reference sulphonylurea agent used in comparative clinical trials. [less ▲]

Detailed reference viewed: 56 (0 ULg)
Full Text
Peer Reviewed
See detailUsing the classification model of an electronic nose to assign unknown malodours to environmental sources and to monitor them continuously
Nicolas, Jacques ULg; Romain, Anne-Claude ULg; Wiertz, Véronique et al

in Sensors and actuators. B, Chemical (2000), 69(3), 366-371

The paper provides some considerations resulting from measurements with electronic noses around real sources of malodour in the environment: compost facilities, printing houses, paint shops, waste water ... [more ▼]

The paper provides some considerations resulting from measurements with electronic noses around real sources of malodour in the environment: compost facilities, printing houses, paint shops, waste water treatment plants, rendering plants, settling ponds of sugar factories. The study aims at supplying the concrete information requested by the final user in the field: either a warning signal when the malodour level exceeds some given threshold value, the identification of the source of an odour detected on site, or on-line identification and monitoring of an odour in the field. Very simple instruments are used, either in the laboratory or directly in the field, with a home-made portable e-nose, based on tin oxide sensors. Even with such simple operating conditions, the classification results with DA and PCA are fairly good. The classification functions calibrated with the statistical procedure, on the basis of the learning phase, are used to recognise and to monitor a given malodour. This odour is sometimes mixed with other odorous interferences in the field. The observations reveal some features useful in the frame of the development of a field detector. [less ▲]

Detailed reference viewed: 63 (2 ULg)
Peer Reviewed
See detailPharma clinics. Le medicament du mois. La cerivastatine (Lipobay, Cholstat).
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(2), 117-20

Cerivastatin, commercialized under the trade names of Lipobay by Bayer and Cholstat by Fournier Pharma, is a new synthetic statin. Because of its high affinity for HMG-CoA reductase enzyme that it ... [more ▼]

Cerivastatin, commercialized under the trade names of Lipobay by Bayer and Cholstat by Fournier Pharma, is a new synthetic statin. Because of its high affinity for HMG-CoA reductase enzyme that it specifically and selectively inhibited in the hepatocytes, cerivastatin exerts its cholesterol-lowering effect at very low doses, between 0.1 and 0.3 mg/day. Cerivastatin is indicated, after diet failure, in the treatment of primary forms of isolated hypercholesterolaemia or combined hyperlipidaemia. It is presented by the two pharmaceutical companies as 0.1, 0.2 and 0.3 mg filmed tablets. Usual dose is 0.3 mg, once daily, to be reduced in presence of renal failure. Cerivastatin is metabolised within the liver by two different families of cytochrome P450, which limits the risk of drug interferences. Besides this potential advantage as compared with some other statins, its pharmacodynamic activity and safety profile seem to be similar to those of other agents of the same pharmacological family. [less ▲]

Detailed reference viewed: 36 (0 ULg)
Peer Reviewed
See detailThe Bureaucracy of Crime : J. G. Ballard’s Cocaine Nights and the Speculative Thriller
Delville, Michel ULg

in Analele Universităţii Oradea - Seria Filologie, Fascicola Limba şi literatura (2000), 8

Detailed reference viewed: 29 (8 ULg)
Full Text
Peer Reviewed
See detailNew strategy for the validation of chromatographic bioanalytical methods
Chapuzet, E.; Mercier, N.; Bervoas-Martin, S. et al

in STP Pharma Pratiques (2000), 10(1), 21-38

Detailed reference viewed: 95 (6 ULg)
Full Text
Peer Reviewed
See detailMuḥibb al-dīn al-Ṭabarī (ob. 694/1295). Un auteur mésestimé ?
Bauden, Frédéric ULg

in Annales Islamologiques (2000), XXXIV

Detailed reference viewed: 39 (6 ULg)
See detailÀ la recherche de l'«art public» dans les villes de la Mésopotamie
Tunca, Önhan ULg

in Art&Fact (2000), 19

Detailed reference viewed: 28 (3 ULg)
Full Text
Peer Reviewed
See detailLocal and Global Constraints in Finite Element Modeling and the Benefits of Nodal and Edge Elements Coupling
Dular, Patrick ULg

in International Compumag Society Newsletter (2000), 7(2), 4-7

Various constraints can be encountered in partial differential problems. On the one hand, there are local constraints, which locally act on fields. These are usually boundary conditions, fixing components ... [more ▼]

Various constraints can be encountered in partial differential problems. On the one hand, there are local constraints, which locally act on fields. These are usually boundary conditions, fixing components of fields, as well as interface conditions, connecting such components. On the other hand, global behaviors of fields can be constrained, leading to define global constraints. It is the case when vector field fluxes and circulations have to be defined, again in order to be either fixed or connected. A finite element model of a partial differential problem, through weak formulations, then leads to split up the considered constraints in two families, known as essential and natural constraints. This means that some constraints are strongly satisfied while others are only weakly satisfied. It is the aim of this paper to make a survey of local and global constraints encountered in finite element models of electromagnetic systems. It particularly points out the benefits of using both nodal and edge finite elements to achieve their consistent discrete definitions. There are indeed properties that are worth to be kept from the continuous to the discrete level. The constraints are defined in the frame of dual formulations in order to point out their dual, or complementary, natures. Systematic explicit characterizations of constrained function spaces are shown to be quite convenient. [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailEffet de l’ammoniac sur la fibre C impliquée dans le réflexe de la toux chez le porc
Moreaux, B.; Nemmar, R.; Gustin, Pascal ULg

in Journées de la Recherche Porcine en France (2000), 32

The effect of ammonia on the C-fibre which is involved in the citric acid induced coughing reflex was assessed. The piglets were exposed during a period of 24 hours or 4 days to a concentration of 15 or ... [more ▼]

The effect of ammonia on the C-fibre which is involved in the citric acid induced coughing reflex was assessed. The piglets were exposed during a period of 24 hours or 4 days to a concentration of 15 or 30 ppm ammonia in an inhalation chamber . During this challenge, the animais underwent cough induction tests at two days intervals. Another group was exposed to ammonia (30 ppm) for 48 hours, after this period, substance P was assayed in liquids collected from broncho-alvealor and tracheal washings (BAL and TAL) and in tracheal and airway mucosa . Ammonia (30 ppm) induced an inhibition 0f the coughing reflex in pigs. The minimum period of exposure necessary to provoke this effect was 48 hours. The same ammonia concentration aiso induced o significant increase in substance P concentrations in BAL and TAL and a significant decrease in concentrations of the tracheal mucosa. We conclude that ammonia at o concentration of 30 ppm inhibits the citric acid induced coughing reflex. The effect was partly mediated by the release of substance P from the C-fibre. [less ▲]

Detailed reference viewed: 54 (3 ULg)
Full Text
Peer Reviewed
See detailSubungual abscess: a new ungual side-effect related to docetaxel therapy
Vanhooteghem, Olivier ULg; Richert, Bertrand ULg; Vindevoghel, A. et al

in British Journal of Dermatology (2000), 143(2), 462-464

Detailed reference viewed: 12 (0 ULg)
Peer Reviewed
See detailSystemic nitroglycerin increases nNOS levels in rat trigeminal nucleus caudalis.
Pardutz, A.; Krizbai, I.; Multon, Sylvie ULg et al

in Neuroreport (2000), 11(14), 3071-5

Systemic administration of nitroglycerin, a nitric oxide donor, triggers in migraineurs a delayed attack of unknown mechanisms. Subcutaneous nitroglycerin (10 mg/kg) produced a significant increase of ... [more ▼]

Systemic administration of nitroglycerin, a nitric oxide donor, triggers in migraineurs a delayed attack of unknown mechanisms. Subcutaneous nitroglycerin (10 mg/kg) produced a significant increase of nitric oxide synthase (NOS)- and c-fos-immunoreactive neurons in the cervical part of trigeminal nucleus caudalis in rats after 4 h. This effect was not observed in the thoracic dorsal horn. Similar increase of NOS and c-fos was obtained in the brain stem after a somatic nociceptive stimulus, i.e. on the side of the formalin injection in the lip. Nitric oxide is thus able to increase NOS availability in second order nociceptive trigeminal neurons, which may be relevant for central sensitization and the understanding of its effect in migraine. [less ▲]

Detailed reference viewed: 43 (1 ULg)
Peer Reviewed
See detailMicroscopic model of ferroelectricity in stress-free PbTiO3 ultrathin films
Ghosez, Philippe ULg; Rabe, K. M.

in Applied Physics Letters (2000), 76(19), 2767-2769

The ground-state polarization of PbTiO3 thin films is studied using a microscopic effective Hamiltonian with parameters obtained from first-principles calculations. Under short-circuit electrical boundary ... [more ▼]

The ground-state polarization of PbTiO3 thin films is studied using a microscopic effective Hamiltonian with parameters obtained from first-principles calculations. Under short-circuit electrical boundary conditions, (001) films with thickness as low as three unit cells are found to have a perpendicularly polarized ferroelectric ground state with significant enhancement of the polarization at the surface. (C) 2000 American Institute of Physics. [S0003- 6951(00)02119-7]. [less ▲]

Detailed reference viewed: 8 (1 ULg)
See detail2e campagne de fouille à Chagar Bazar (Syrie)
Tunca, Önhan ULg; McMahon, A.; Baghdo, Abd el-Massih

in Orient-Express 2000/4 (2000)

Detailed reference viewed: 42 (5 ULg)
Full Text
Peer Reviewed
See detailOppositions locales et dynamiques d'environnementalisation
Mormont, Marc ULg; Bertrand, Anne

in Espaces et Sociétés (Paris, France) (2000), (101-102), 93-112

Local conflicts provoke collective action that through new coalitions induce reformulations of the problems and elarge scope and scaling of environmental problems. These processes are called ecologization ... [more ▼]

Local conflicts provoke collective action that through new coalitions induce reformulations of the problems and elarge scope and scaling of environmental problems. These processes are called ecologization dynamics and are going to transform environmental politics. [less ▲]

Detailed reference viewed: 125 (18 ULg)
Full Text
Peer Reviewed
See detailSibling cannibalism in dorada under experimental conditions. I. Ontogeny, dynamics, bioenergetics of cannibalism and prey size selectivity
Baras, E.; Ndao, E.; Maxi, M. et al

in Journal of Fish Biology (2000), 57

Detailed reference viewed: 34 (13 ULg)
Peer Reviewed
See detailCellulite: from standing fat herniation to hypodermal stretch marks.
Pierard, Gérald ULg; NIZET, Jean-Luc ULg; PIERARD-FRANCHIMONT, Claudine ULg

in American Journal of Dermatopathology (2000), 22(1), 34-7

There are glaring discrepancies in the microanatomical descriptions of cellulite in the literature. We revisited this common skin condition in women with a microscopic examination of 39 autopsy specimens ... [more ▼]

There are glaring discrepancies in the microanatomical descriptions of cellulite in the literature. We revisited this common skin condition in women with a microscopic examination of 39 autopsy specimens. A control group consisted of 4 women and 11 men showing no evidence of cellulite. The lumpy aspect of the dermohypodermal interface appeared to represent a gender-linked characteristic of the thighs and buttocks without being a specific sign of cellulite. Incipient cellulite identified by the mattress phenomenon was related to the presence of focally enlarged fibrosclerotic strands partitioning the subcutis. Such strands possibly serve as a physiologic buttress against fat herniation limiting the outpouching of fat lobules on pinching the skin. These structures might represent a reactive process to sustained hypodermal pressure caused by fat accumulation. Full-blown cellulite likely represents subjugation of the hypertrophic response when connective tissue is overcome by progressive fat accumulation. Histologic aspects reminiscent of stretch marks are identified within the hypodermal strands, resulting in clinical skin dimpling. [less ▲]

Detailed reference viewed: 35 (3 ULg)
Peer Reviewed
See detailCore-polarization effects in the Cadmium Isoelectronic Sequence
Biémont, Emile ULg; Froese Fischer, C.; Godefroid, M. R. et al

in Physical Review. A (2000), 62

Detailed reference viewed: 9 (2 ULg)
Full Text
See detailRéhabilitation du pont barrage de Montignie-Saint-Christophe
Lejeune, André ULg; Pirotton, Michel ULg

in Cahiers de l'Urbanisme (Les) (2000)

Detailed reference viewed: 19 (2 ULg)
Full Text
Peer Reviewed
See detailMass Transfer Across an Interface Induces Formation of Droplets in Lattice Systems
Pfennig, Andreas ULg

in Chemical Engineering Science (2000), 55(22), 5333-5339

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailSynthesis of an array antenna for hyperthermia applications
V Sabariego, Ruth ULg; Landesa, Luis; Obelleiro, Fernando

in IEEE Transactions on Magnetics (2000), 36(4), 1696-1699

In the present work the synthesis of an array antenna for hyperthermia treatment is developed. The selected antenna is an array antenna surrounded by a semicircular reflector which has shown to ease the ... [more ▼]

In the present work the synthesis of an array antenna for hyperthermia treatment is developed. The selected antenna is an array antenna surrounded by a semicircular reflector which has shown to ease the penetration and focalization in malignant biological tissues. A bolus is introduced as a protection in order to avoid an increasing heat hazard of superficial healthy tissues. The electric field within the biological medium will be modeled by means of the well known method of moments. The electromagnetic coupling problem is expressed in a closed form, enabling both a synthesis and an optimization procedure to be performed. Numerical results are included, illustrating the capabilities of the array antenna. [less ▲]

Detailed reference viewed: 24 (2 ULg)
Peer Reviewed
See detailComment évaluer le raisonnement géométrique ?
Jehin, Monique ULg; Chenu, Florent ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), (3-4), 67-85

Detailed reference viewed: 37 (3 ULg)
Peer Reviewed
See detailExpression And Activity Of Antioxidant Enzymes During Potato Tuber Dormancy
Rojas-Beltran, Ja.; Dejaeghere, F.; Kotb, Ma. et al

in Potato Research (2000), 43(4),

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailIncreased synovial fluid levels of interleukin-12, sCD25 and sTNF-RII/sTNF-RI ratio delineate a cytokine pattern characteristic of immune arthropathies
Ribbens, Clio ULg; Andre, Béatrice ULg; Kaye, O. et al

in European Cytokine Network (2000), 11(4), 669-676

The assessment of cytokines and their soluble receptors in the synovial fluid (SF) of inflammatory arthropathies may be useful in studying pathogenetic and immunoregulatory mechanisms underlying different ... [more ▼]

The assessment of cytokines and their soluble receptors in the synovial fluid (SF) of inflammatory arthropathies may be useful in studying pathogenetic and immunoregulatory mechanisms underlying different diseases. The aim of this work was to study the cytokine network occurring in inflammatory arthropathies and to identify a cytokine profile which is characteristic of an immune-mediated synovitis. Levels of IL-12, as well as IL-4, IL-8, IL-10, IFN-gamma, sCD25, TNF-alpha and its soluble receptors were measured in the SF of various arthropathies, i.e. non-inflammatory arthropathies: "control" meniscus pathology (n = 21), osteoarthritis (n = 22) and chronic crystal arthritis (n = 9); a non-immune inflammatory arthropathy: acute crystal arthritis (n = 11); 2 immune inflammatory arthropathies: reactive arthritis (ReA) (n = 23) and rheumatoid arthritis (RA) (n = 44). SF levels of IL-10, TNF-alpha and sTNF-RII were found to be increased in the three inflammatory arthropathies compared to the "control" meniscus group. Within the inflammatory group, acute crystal arthritis was characterized by a significantly higher sTNF-RI/TNF-alpha ratio and ReA by a significantly lower sTNF-RII/TNF-alpha ratio compared to the two other diseases. The two immune arthropathies, RA and ReA, were characterized by increased SF levels of IL-12, sCD25 and of the sTNF-RII/sTNF-RI ratio. ReA differed however from RA by showing lower IL-8 and IL-4 levels, higher IFN-gamma levels and a higher IL-12/IL-10 ratio, suggesting a more prevalent Th1 profile in ReA SF. Our data indicate that the measurement of SF cytokines and soluble receptors may discriminate between each inflammatory arthropathy and might be useful in clinical practice. [less ▲]

Detailed reference viewed: 26 (2 ULg)
Full Text
Peer Reviewed
See detailA potent diazoxide analogue activating ATP-sensitive K+ channels and inhibiting insulin release
Lebrun, P.; Arkhammar, P.; Antoine, M.-H. et al

in Diabetologia (2000), 43

Detailed reference viewed: 16 (4 ULg)
Full Text
Peer Reviewed
See detailCharacteristics of the iron moment in Dy-Fe and Dy-FeCo amorphous alloys studied by X-ray magnetic circular dichroism
Fleury-Frenette, Karl ULg; Dhesi, S. S.; van der Laan, G. et al

in Journal of Magnetism & Magnetic Materials (2000), 220(1), 45-51

The local magnetic moment of Fe in Dy-Fe and Dy-FeCo amorphous alloys has been studied using X-ray absorption spectroscopy and X-ray magnetic circular dichroism (XMCD). The Fe orbital and spin magnetic ... [more ▼]

The local magnetic moment of Fe in Dy-Fe and Dy-FeCo amorphous alloys has been studied using X-ray absorption spectroscopy and X-ray magnetic circular dichroism (XMCD). The Fe orbital and spin magnetic moments have been obtained for a range of alloy compositions by applying the sum rules to the XMCD spectra. The room temperature variations of the average components of the Fe moments as a function of Dy concentration and with the substitution of Fe by Co have been determined. A sharp reversal of the total magnetic moment was found at 28 +/- 1 at% Dy for both alloys. (C) 2000 Elsevier Science B.V. All rights reserved. [less ▲]

Detailed reference viewed: 35 (4 ULg)
Full Text
Peer Reviewed
See detailPalladium-silver sol-gel catalysts for selective hydrodechlorination of 1,2-dichloroethane into ethylene II. Surface composition of alloy particles
Heinrichs, Benoît ULg; Noville, Francis ULg; Schoebrechts, Jean-Paul et al

in Journal of Catalysis (2000), 192(1), 108-118

The surface composition of alloy particles in Pd-Ag/SiO2 hydrodechlorination (HDC) sol-gel catalysts has been determined by combining three experimental techniques, carbon monoxide chemisorption, X-ray ... [more ▼]

The surface composition of alloy particles in Pd-Ag/SiO2 hydrodechlorination (HDC) sol-gel catalysts has been determined by combining three experimental techniques, carbon monoxide chemisorption, X-ray diffraction, and transmission electron microscopy, Values obtained through this method show a very marked silver enrichment of the surface, as expected: as a consequence of the important gap between palladium and silver surface energies. These values are in complete agreement with surface composition curves calculated in other studies by means of Auger electron spectroscopy and infrared spectroscopy. The influence of sample pretreatment temperature as well as the influence of carbon monoxide on surface composition are discussed. (C) 2000 Academic Press. [less ▲]

Detailed reference viewed: 41 (4 ULg)
See detailEffectuer l'état des lieux, la réactivation et la rémédiation des bases de chimie à la charnière entre l'enseignement secondaire et l'Université sur http://www.ulg.ac.be/grptrans/
Müller, Robert; Cornélis, André; Cahay, René et al

in Bulletin de l'Association Belge des Professeurs de Physique et de Chimie (2000), (144), 30-40

Detailed reference viewed: 14 (0 ULg)
Peer Reviewed
See detail“E andè drétt u n s va invéll”: Percorsi di Raffaello Baldini
Benzoni, Pietro ULg

in Studi novecenteschi (2000), XXVII(59), 7-57

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailMechanisms of reduced and compensatory growth.
Hornick, Jean-Luc ULg; Van Eenaeme, Christian ULg; Gerard, O. et al

in Domestic Animal Endocrinology (2000), 19(2), 121-32

Growth is an integrated process, resulting from the response of cells dependent on the endocrine status and nutrient availability. During feed restriction, the production and secretion of growth hormone ... [more ▼]

Growth is an integrated process, resulting from the response of cells dependent on the endocrine status and nutrient availability. During feed restriction, the production and secretion of growth hormone (GH) by the pituitary gland are enhanced, but the number of GH receptors decreases. Changes of GH binding proteins induce GH resistance and are followed by reduced insulin-like growth factor-I (IGF-I) secretion. On the other hand, high circulating levels of GH enhance the mobilization of fatty acids, which are used to support energy requirements. Thus, when feed restriction in growing animals is moderate, there is mainly protein but barely fat accretion. By contrast, a severe feed restriction enhances the release of catabolic hormones and stimulates, from muscle cells, the liberation of amino acids, which are used by hepatocytes for gluconeogenesis. During refeeding and compensatory growth, the secretion of insulin is sharply enhanced and plasma GH concentrations remain high. This situation probably allows more nutrients to be used for growth processes. The role of plasma IGF-I during compensatory growth is not clear and must be explained in connection with changes of its binding proteins. Thyroxin and 3,5,3'-triiodothyronine seem to have a permissive effect on growth. The simultaneous occurrence of puberty with refeeding can exert a synergistic effect on growth. Initially, compensatory growth is characterized by the deposition of very lean tissue, similar as during feed restriction. This lasts for some weeks. Then, protein synthesis decreases and high feed intake leads to increased fat deposition. [less ▲]

Detailed reference viewed: 85 (10 ULg)
Full Text
Peer Reviewed
See detailIdentification de cultivars de palmier dattier (Phoenix dactylifera L.) par l'amplification aléatoire d'ADN (RAPD)
Ben Abdallah, Abdallah; Stiti, Kadija; Du Jardin, Patrick ULg et al

in Cahiers Agricultures (2000), 9(2), 103-107

Detailed reference viewed: 1890 (3 ULg)
Full Text
Peer Reviewed
See detailDerived Categories for Functional Analysis
Prosmans, Fabienne ULg

in Publications of the Research Institute for Mathematical Sciences (2000), 36(1), 19-83

We study the homological algebra of the category of locally convex topological vector spaces from the point of view of derived categories.

Detailed reference viewed: 40 (18 ULg)
Full Text
Peer Reviewed
See detailLong-Term Protection Against Bovine Leukaemia Virus Replication In Cattle And Sheep
Kerkhofs, P.; GATOT, Jean-Stéphane ULg; Knapen, K. et al

in Journal of General Virology (2000), 81

Detailed reference viewed: 15 (3 ULg)
Full Text
See detailLe mélèze, une essence à haut potentiel de production
Pauwels, Dominique; Rondeux, Jacques ULg

in Silva Belgica (2000), 107(3), 6-10

Dans un précédent article "le mélèze, un atout dans les objectifs de diversification de notre sylviculture" (PAUWELS et RONDEUX, 2000), nous nous sommes efforcés de montrer que la culture du mélèze ... [more ▼]

Dans un précédent article "le mélèze, un atout dans les objectifs de diversification de notre sylviculture" (PAUWELS et RONDEUX, 2000), nous nous sommes efforcés de montrer que la culture du mélèze méritait, à plusieurs égards, d'être davantage prise en compte en Région wallonne et ce, pour autant qu'une sylviculture adaptée à l'essence et aux conditions du milieu soit appliquée. Les lignes qui suivent sont consacrées à des résultats originaux résultant d'une étude menée par l'Unité de Gestion et Economie forestières de la Faculté universitaire des Sciences agronomiques de Gembloux, sur la croissance des mélèzes en Région wallonne. Le potentiel de croissance du mélèze a été évalué à partir d'analyses de tiges ou de mesures réalisées au sein de placettes de production (figure 1) remesurées tous les 3 ans. A partir d'une exploitation appropriée de ces données, on a déduit une gamme de traitements sylvicoles capables de rencontrer les objectifs de production que l'essence permet d'atteindre. [less ▲]

Detailed reference viewed: 113 (6 ULg)
Full Text
Peer Reviewed
See detailAutomatisation d'un banc de répartition pour buses de pulvérisation
Lebeau, Frédéric ULg; Hamza, Elies; Destain, Marie-France ULg

in Cahiers Agricultures (2000)

Les bancs de répartition constituent l'élement de base permettant de tester la sensibilité de la distribution transversale des buses de pulvérisation aux différents paramètres de fonctionnement. L'article ... [more ▼]

Les bancs de répartition constituent l'élement de base permettant de tester la sensibilité de la distribution transversale des buses de pulvérisation aux différents paramètres de fonctionnement. L'article présente un banc d'essai conforme à la norme ISO 5682/1 qui permet une lecture automatisée des différentes grandeurs (pression, débit, volume recueilli). [less ▲]

Detailed reference viewed: 112 (28 ULg)
Full Text
Peer Reviewed
See detailFractal characterization of wide pore range catalysts: Application to Pd-Ag/SiO2 xerogels
Blacher, Silvia ULg; Heinrichs, Benoît ULg; Sahouli, Bendida et al

in Journal of Colloid & Interface Science (2000), 226(1), 123-130

Fractal analysis has been applied to characterize the structure of Pd-Ag/SiO2 catalysts dried under vacuum (150 degrees C and 12 hPa) with different concentrations of Pd-Ag, Nitrogen adsorption-desorption ... [more ▼]

Fractal analysis has been applied to characterize the structure of Pd-Ag/SiO2 catalysts dried under vacuum (150 degrees C and 12 hPa) with different concentrations of Pd-Ag, Nitrogen adsorption-desorption, mercury porosimetry, and small-angle X-ray scattering measurements have been used. The different approaches to fractal analysis and their conditions of applicability are briefly described. Results are discussed in relation to those derived previously from classical interpretations. This analysis shows that Pd-Ag/SiO2 xerogels exhibit a very open self-similar pore structure analogous to the structure of supercritically dried aerogels and that the micropore texture can be tailored by varying the silver content. (C) 2000 Academic Press. [less ▲]

Detailed reference viewed: 51 (13 ULg)
Full Text
Peer Reviewed
See detailTechnical efficiency of European railways: a distance function approach
Coelli, Tim; Perelman, Sergio ULg

in Applied Economics (2000), 32

This study has two principal objectives. The first objective is to measure and compare the performance of European railways. The second objective is to illustrate the usefulness of econometric distance ... [more ▼]

This study has two principal objectives. The first objective is to measure and compare the performance of European railways. The second objective is to illustrate the usefulness of econometric distance functions in the analysis of production in multioutput industries, where behavioural assumptions such as cost minimization or profit maximization, are unlikely to be applicable. Using annual data on 17 railways companies during 1988± 1993, multioutput distance functions are estimated using corrected ordinary least squares (COLS). The resulting technical efficiency estimates range from 0.980 for the Netherlands to 0.784 for Italy, with a mean of 0.863. The distance function results are also compared with those obtained from single-output production functions, where aggregate output measures are formed using either total revenue or a Tornqvist index. The results obtained indicate substantial differences in parameter estimates and technical efficiency rankings, casting significant doubt upon the reliability of these single-output models, particularly when a total revenue measure is used to proxy aggregate output. [less ▲]

Detailed reference viewed: 150 (2 ULg)
Full Text
Peer Reviewed
See detailOn the scalar meson exchange in the baryon spectra
Stassart, Pierre ULg; Stancu, Floarea ULg; Richard, J. M. et al

in Journal of Physics : G Nuclear & Particle Physics (2000), G26

We explore the role of a scalar meson exchange interaction between quarks in a semirelativistic constituent quark model where the quarks are also subject to a linear confinement. We study how the spectrum ... [more ▼]

We explore the role of a scalar meson exchange interaction between quarks in a semirelativistic constituent quark model where the quarks are also subject to a linear confinement. We study how the spectrum evolves when the strength of the scalar meson exchange increases. Our results are relevant to the long-standing problem of the relative position of the first positive-parity (Roper resonance) and the first orbitally excited states in the baryon spectrum. [less ▲]

Detailed reference viewed: 12 (3 ULg)
Full Text
Peer Reviewed
See detailCoupled thermo-magnetic simulation of a foil-winding transformer connected to a non-linear load
Driesen, Johan; Deliège, Geoffrey ULg; Belmans, Ronnie et al

in IEEE Transactions on Magnetics (2000), 36(4), 1381-1385

Detailed reference viewed: 15 (0 ULg)
Peer Reviewed
See detailL'image du mois. Thrombose de la veine porte
Ancion, G.; Delwaide, Jean ULg; Boverie, Jacques ULg

in Revue Médicale de Liège (2000), 55(8), 761-762

Detailed reference viewed: 28 (9 ULg)
Peer Reviewed
See detailUse of stable isotope to delineate amphipod trophic status in Antarctic food webs
Nyssen, Fabienne ULg

in Polish Archives of Hydrobiology (2000), 47

Detailed reference viewed: 32 (9 ULg)
Full Text
Peer Reviewed
See detailA homologous radioimmunoassay for quantification of insulin-like growth factor-binding protein-2 in blood from cattle.
Vleurick, Lieve; Renaville, Robert ULg; VandeHaar, M. et al

in Journal of Dairy Science (2000), 83(3), 452-8

Insulin-like growth factor-I and -II (IGF-I, IGF-II) circulate in biological fluids bound to six different IGF-binding proteins that regulate IGF bioactivity. The IGF-binding protein-2 is regulated by ... [more ▼]

Insulin-like growth factor-I and -II (IGF-I, IGF-II) circulate in biological fluids bound to six different IGF-binding proteins that regulate IGF bioactivity. The IGF-binding protein-2 is regulated by growth hormones, and its concentration depends on nutrition and physiological state. Specific antibodies directed against bovine IGF-binding protein-2 were produced, and IGF-binding protein-2 levels in bovine blood samples were quantified by radioimmunoassay. Parallel displacement curves showed strong cross-reactivity with bovine and ovine plasma, were low with porcine plasma, and no cross-reactivity with rat or chicken plasma. Addition of IGF-I or -II to a control pool of bovine plasma did not significantly alter control IGF-binding protein-2 values in a radioimmunoassay. Six nycthemeral periods, determined for three young bulls bled on two occasions, showed that IGF-binding protein-2 plasma levels were stable throughout the day; two or three samples were sufficient to characterize the animal. Cows treated with recombinant bovine somatotropin (bST) had significantly lower serum levels of IGF-binding protein-2 than did control cows. Furthermore, IGF-binding protein-2 levels were dramatically increased at the onset of lactation. This radioimmunoassay for bovine IGF-binding protein-2, which enables quantitative assessment of IGF-binding protein-2 concentration in cattle, confirmed that IGF-binding protein-2 concentrations are depressed by administration of bST, enhanced after calving, and showed absence of diurnal variation. [less ▲]

Detailed reference viewed: 75 (15 ULg)
Full Text
Peer Reviewed
See detailEffective treatment of Jo-1-associated polymyositis with T-cell-depleted autologous peripheral blood stem cell transplantation.
Baron, Frédéric ULg; Ribbens, Clio ULg; Kaye, O. et al

in British Journal of Haematology (2000), 110(2), 339-342

A patient with Jo-1 antibody-associated polymyositis (Jo-1 PM) had a Karnofsky score of 40% and severe muscle, liver and lung damage that was refractory to standard therapy. The female patient received an ... [more ▼]

A patient with Jo-1 antibody-associated polymyositis (Jo-1 PM) had a Karnofsky score of 40% and severe muscle, liver and lung damage that was refractory to standard therapy. The female patient received an autologous T-cell-depleted haematopoietic stem cell transplant (HSCT) after myeloablative conditioning. The transplant procedure was complicated by severe adult respiratory distress syndrome (ARDS) and adenovirus-associated haemorrhagic cystitis as well as cytomegalovirus (CMV) reactivation. The patient's creatinine phosphokinase (CPK) and alanine transaminase (ALT) values were normal on day 21. The patient's strength has improved remarkably and her dyspnoea is subjectively improved. At 15 months after the transplant, the patient was well with a Karnofsky score of 80% and had been off any therapy, including steroids, for 14 months. [less ▲]

Detailed reference viewed: 36 (0 ULg)
Peer Reviewed
See detailMonitoring des animaux vivants : exemple d’un échantillonnage pour la détection des PCBs et des dioxines chez les bovins de boucherie en Belgique
Saegerman, Claude ULg; Boelaert, F.; Van Vlanderen, I. et al

in Epidémiologie et Santé Animale (2000), 38

In February 1999, a poisoning episode broke out in several industrial poultry farms in Belgium. The source of this contamination was found to be a stock of recycled fat that had been delivered by a firm ... [more ▼]

In February 1999, a poisoning episode broke out in several industrial poultry farms in Belgium. The source of this contamination was found to be a stock of recycled fat that had been delivered by a firm to several compound feed producers, between 19 and 31 January 1999. A very good correlation was observed between dioxins (PCDFs and PCDDs) and PCBs. Consequently a contamination mainly by PCBs was hypothesized. This finding made it possible to detect contaminated animals and animal products by dosage of the PCBs, more specifically by the 7 congeners with numbers 28, 52, 101, 118, 138, 153 and 180. The advantages of the dosage of PCBs compared to dioxins were its rapid test protocol and the fact that a larger number of laboratories could participate. In the cattle sector, 409 herds (0,81 p. cent) were submitted to the risk of feed contamination. The methodology used to detect a PCBs/dioxins contamination in the Belgian cattle population that was not submitted to the risk, is presented. This population is directly or indirectly destined for human consumption. It consisted in the systematic sampling of all calve fattening stations and all lots of exported bovines, and in the random sampling of slaughter cattle. This methodology is compared to the approach described in directive 96/23/CE. [less ▲]

Detailed reference viewed: 78 (5 ULg)
Full Text
Peer Reviewed
See detailResource Trading Agents for Adaptive Active Network Applications
Yamamoto, Lidia; Leduc, Guy ULg

in Networking and Information Systems Journal (2000), 3(4-5), 743-768

Adaptive applications seem to be the only realistic answer to the increasing diversity and decentralisation in networks. In order to accommodate fluctuations in network conditions, adaptive applications ... [more ▼]

Adaptive applications seem to be the only realistic answer to the increasing diversity and decentralisation in networks. In order to accommodate fluctuations in network conditions, adaptive applications need to obtain information about resource availability. Using mobile agent technology applied to active networks, new models for adaptive applications can be envisaged. In this article we review the state of the art in agent and active network techniques for adaptive applications, and describe our work on an agent model for trading resources inside an active network node. We apply the model to the case of an audio mixing application. Our simulation results indicate that the model allows the application to make efficient use of the available resources, and to share resources according to user preferences. [less ▲]

Detailed reference viewed: 15 (0 ULg)
See detailCompétition et choix du partenaire sexuel chez les primates
Huynen, Marie-Claude ULg

in Cahiers d'Ethologie (2000), 20(1), 85-112

Detailed reference viewed: 18 (0 ULg)
Peer Reviewed
See detailCrystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family.
Bompard-Gilles, C.; Remaut, H.; Villeret, V. et al

in Structure (2000), 8(9), 971-80

BACKGROUND: beta-Lactam compounds are the most widely used antibiotics. They inactivate bacterial DD-transpeptidases, also called penicillin-binding proteins (PBPs), involved in cell-wall biosynthesis ... [more ▼]

BACKGROUND: beta-Lactam compounds are the most widely used antibiotics. They inactivate bacterial DD-transpeptidases, also called penicillin-binding proteins (PBPs), involved in cell-wall biosynthesis. The most common bacterial resistance mechanism against beta-lactam compounds is the synthesis of beta-lactamases that hydrolyse beta-lactam rings. These enzymes are believed to have evolved from cell-wall DD-peptidases. Understanding the biochemical and mechanistic features of the beta-lactam targets is crucial because of the increasing number of resistant bacteria. DAP is a D-aminopeptidase produced by Ochrobactrum anthropi. It is inhibited by various beta-lactam compounds and shares approximately 25% sequence identity with the R61 DD-carboxypeptidase and the class C beta-lactamases. RESULTS: The crystal structure of DAP has been determined to 1.9 A resolution using the multiple isomorphous replacement (MIR) method. The enzyme folds into three domains, A, B and C. Domain A, which contains conserved catalytic residues, has the classical fold of serine beta-lactamases, whereas domains B and C are both antiparallel eight-stranded beta barrels. A loop of domain C protrudes into the substrate-binding site of the enzyme. CONCLUSIONS: Comparison of the biochemical properties and the structure of DAP with PBPs and serine beta-lactamases shows that although the catalytic site of the enzyme is very similar to that of beta-lactamases, its substrate and inhibitor specificity rests on residues of domain C. DAP is a new member of the family of penicillin-recognizing proteins (PRPs) and, at the present time, its enzymatic specificity is clearly unique. [less ▲]

Detailed reference viewed: 13 (0 ULg)
Peer Reviewed
See detailQuoi de neuf dans le domaine de l'obesite?
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(7), 756-9

We will briefly comment on some interesting topics presented at the 10th European Congress on Obesity (ECO, Antwerp, Belgium, 24-27 May 2000). Special attention has been focused upon: 1) the multi ... [more ▼]

We will briefly comment on some interesting topics presented at the 10th European Congress on Obesity (ECO, Antwerp, Belgium, 24-27 May 2000). Special attention has been focused upon: 1) the multi-endocrine function of the adipocyte cell; 2) the role of gene-environment interactions; 3) the regulatory mechanisms of energy balance; 4) the neuroendocrine hypothesis for the development of visceral adiposity; 5) the numerous complications associated with obesity, more particularly type 2 diabetes; and, finally, 6) obesity prevention, especially in childhood, and new pharmacological perspectives for the treatment of obesity. [less ▲]

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailThe antiangiogenic factor 16K PRL induces programmed cell death in endothelial cells by caspase activation
Martini, J. F.; Piot, C.; Humeau, L. M. et al

in Molecular Endocrinology (2000), 14(10), 1536-49

We asked whether the antiangiogenic action of 16K human PRL (hPRL), in addition to blocking mitogen-induced vascular endothelial cell proliferation, involved activation of programmed cell death. Treatment ... [more ▼]

We asked whether the antiangiogenic action of 16K human PRL (hPRL), in addition to blocking mitogen-induced vascular endothelial cell proliferation, involved activation of programmed cell death. Treatment with recombinant 16K hPRL increased DNA fragmentation in cultured bovine brain capillary endothelial (BBE) and human umbilical vein endothelial (HUVE) cells in a time- and dose-dependent fashion, independent of the serum concentration. The activation of apoptosis by 16K hPRL was specific for endothelial cells, and the activity of the peptide could be inhibited by heat denaturation, trypsin digestion, and immunoneutralization, but not by treatment with the endotoxin blocker, polymyxin-B. 16K hPRL-induced apoptosis was correlated with the rapid activation of caspases 1 and 3 and was blocked by pharmacological inhibition of caspase activity. Caspase activation was followed by inactivation of two caspase substrates, poly(ADP-ribose) polymerase (PARP) and the inhibitor of caspase-activated deoxyribonuclease (DNase) (ICAD). Furthermore, 16K hPRL increased the conversion of Bcl-X to its proapoptotic form, suggesting that the Bcl-2 protein family may also be involved in 16K hPRL-induced apoptosis. These findings support the hypothesis that the antiangiogenic action of 16K hPRL includes the activation of programmed cell death of vascular endothelial cells. [less ▲]

Detailed reference viewed: 19 (4 ULg)
See detailSimenon critique de Simenon. Éléments pour une reconstitution de l'espace des possibles romanesques simenoniens (1938-1948)
Denis, Benoît ULg

in Traces. Travaux du Centre d'Études Georges Simenon (2000), (12), 27-46

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailProteolytic cleavage confers nitric oxide synthase inducing activity upon prolactin
Corbacho, A. M.; Nava, G.; Eiserich, J. P. et al

in Journal of Biological Chemistry (2000), 275(18), 13183-6

Prolactin (PRL), originally associated with milk secretion, is now known to possess a wide variety of biological actions and diverse sites of production beyond the pituitary. Proteolytic cleavage is a ... [more ▼]

Prolactin (PRL), originally associated with milk secretion, is now known to possess a wide variety of biological actions and diverse sites of production beyond the pituitary. Proteolytic cleavage is a common post-translational modification that can either activate precursor proteins or confer upon the peptide fragment unique biological actions not exerted by the parent molecule. Recent studies have demonstrated that the 16-kDa N-terminal proteolytic cleavage product of PRL (16K-PRL) acts as a potent inhibitor of angiogenesis. Despite previous demonstrations of 16K-PRL production in vivo, biological functions beyond its antiangiogenic actions remain unknown. Here we show that 16K-PRL, but not full-length PRL, acts to promote the expression of the inducible isoform of nitric oxide synthase (iNOS) and nitric oxide (*NO) production by pulmonary fibroblasts and alveolar type II cells with potency comparable with the proinflammatory cytokines interleukin-1beta, interferon gamma, and tumor necrosis factor alpha. The differential effect of 16K-PRL versus PRL occurs through a receptor distinct from known PRL receptors. Additionally, pulmonary fibroblasts express the PRL gene and endogenously produce 16K-PRL, suggesting that this pathway may serve both autocrine and paracrine roles in the regulation of *NO production. These results reveal that proteolytic cleavage of PRL confers upon this classical hormone potent iNOS inducing activity, suggesting its role in inflammatory/immune processes. [less ▲]

Detailed reference viewed: 19 (1 ULg)
Full Text
See detailLiège et Voltaire
Droixhe, Daniel ULg

in Bulletin de l'Académie Royale de Langue et de Littérature Françaises (2000), LXXVIII(1-2-3-4), 39-48

Detailed reference viewed: 45 (7 ULg)
Full Text
Peer Reviewed
See detailErythropoiesis and renal transplant pregnancy.
Magee, L. A.; von Dadelszen, P.; Darley, J. et al

in Clinical Transplantation (2000), 14(2), 127-35

OBJECTIVE: To examine erythropoiesis in renal transplant pregnancies. METHODS: Retrospective cohort study of 30 renal transplant cases and 30 age, smoking and parity-matched healthy controls with normal ... [more ▼]

OBJECTIVE: To examine erythropoiesis in renal transplant pregnancies. METHODS: Retrospective cohort study of 30 renal transplant cases and 30 age, smoking and parity-matched healthy controls with normal index pregnancy. Retrospective chart review and assay of frozen antenatal serum (for serum erythropoietin concentration [serum EPO]), transferrin receptor protein [TfR], ferritin, folate and B12) were performed. The linear regression equation for normal pregnancy controls was used to calculate predicted [serum EPO] and the observed/predicted (O/P) log [serum EPO] was plotted. The relationship between [serum EPO] and haemoglobin (Hb) among transplant cases was considered to be different from that among controls if the slope of the O/P log [serum EPO] versus Hb regression was significantly different from zero. RESULTS: The transplant (14 cadaveric) to conception interval was (median [range]) 33.5 [4, 189] months. Immunosuppressants were azathioprine (n = 25), cyclosporine (n = 22) and/or prednisone (n = 25). Cases were more often primiparous (20 vs. 7 [controls]; p = 0.01), had pre-existent hypertension (20 vs. 0 [controls]; p < 0.001), developed new/increased hypertension or pre-eclampsia (28 vs. 0 [controls]; p < 0.001) and an antenatal rise in creatinine (14 vs. 2 [controls]; p < 0.001). In early pregnancy, cases had similar EPO (15.2 [2.6, 84.6] vs. 15.7 [6.4, 41.0] [controls] U/L) but lower Hb (101 [65, 129] vs. 116 [106, 150] g/L; p < 0.001). Twenty-two (73%) cases had Hb < 100 g/L (vs. 4 [controls]; p < 0.0001); Hb was comparable at 6 wk postpartum. With advancing gestational age (GA), Hb remained stable and serum EPO increased in both groups. The slope of the O/P log [serum EPO] versus Hb for transplant cases was significantly different from zero within both the 17-28 wk (slope +/- SEM: 0.010 +/- 0.002; p < 0.0001) and the 29-42 wk GA categories (0.006 +/- 0.003; p = 0.02). Cases showed smaller rises in serum TfR (change 481 [- 1471, 2780]) vs. 1119 [- 698, 4195] [controls] ng/mL; p = 0.005). CONCLUSIONS: Anaemia frequently complicates renal transplant pregnancies, in which serum EPO is inappropriately low and the rate of erythropoiesis blunted. [less ▲]

Detailed reference viewed: 22 (0 ULg)
Peer Reviewed
See detailIpsilateral motor responses to focal TMS in normal man and stroke patients.
ALAGONA G.; DELVAUX, Valérie ULg; Delwaide, Paul ULg et al

in Clinical Neurophysiology (2000), 111(Suppl. 1), 11512-05

Detailed reference viewed: 24 (4 ULg)