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See detailModulation of human chondrocyte metabolism by recombinant human interferon.
Henrotin, Yves ULg; Zheng, S X; Labasse, A H et al

in Osteoarthritis and Cartilage (2000), 8(6), 474-82

OBJECTIVES: Interferon gamma (IFN gamma) is found to be elevated in the synovial fluid of patients with rheumatoid arthritis and osteoarthritis, suggesting its implication in joint disease pathogenesis ... [more ▼]

OBJECTIVES: Interferon gamma (IFN gamma) is found to be elevated in the synovial fluid of patients with rheumatoid arthritis and osteoarthritis, suggesting its implication in joint disease pathogenesis. In this study, we investigated the effects of IFN gamma on the production of cytokines (IL-6, IL-8, IL-10), prostaglandin E(2)(PGE(2)), proteoglycans (PG), nitric oxide (NO), interleukin-1 receptor antagonist (IL-1ra) and stromelysin by non-stimulated and IL-1 beta-treated human chondrocytes. The role played by NO in the responses of chondrocytes to IFN gamma was also examined by incubation of chondrocytes with N(G)-monomethyl-L-arginine (L-NMMA), a competitive inhibitor of NO synthase. METHODS: Enzymatically isolated human chondrocytes were cultured for 48 h in the absence or presence of IL-1 beta, IFN gamma or N(G)-monomethyl-L-arginine (L-NMMA) added solely or in combination. The productions of IL-6, IL-8, IL-10, IL-1ra and stromelysin were measured by enzyme amplified sensitivity immunoassays (EASIA). PG and PGE(2)were quantified by specific radioimmunoassays (RIA). Nitrite concentrations in the culture supernatants were determined by a spectrophotometric method based upon the Griess reaction. RESULTS: As expected, IL-1 beta highly stimulated NO, IL-6, IL-8, IL-10, IL-1ra, PGE(2)and stromelysin synthesis, but dramatically decreased PG production. NO, IL-6, IL-1ra and PGE(2)production by non-stimulated chondrocytes was dose-dependently increased by IFN gamma while PG production was inhibited. In the absence of IL-1 beta, IL-10 was undetectable in the culture supernatants. At the doses of 10 and 100 U/ml, IFN gamma markedly inhibited the constitutive and IL-1 beta-stimulated IL-8, IL-10 and stromelysin productions. Interestingly, IFN gamma synergized with IL-1 beta to increase NO, IL-6, IL-1ra and to depress PG production. As previously reported, the inhibition of NO synthesis by the competitive inhibitor L-NMMA led to enhancement of IL-6, IL-8 and PGE(2)production by IL-1 beta treated chondrocytes, but did not significantly modify IL-10, PG and MMP-3 productions. Inhibition of NO synthase significantly inhibited the stimulating effect of IFN gamma on IL-6 and IL-1ra but did not affect the inhibitory effect of IFN gamma on IL-8, PG or stromelysin production. CONCLUSIONS: These findings suggest that IFN gamma and IL-1 synergistically stimulate the production of IL-6, IL-1ra, NO and PGE(2)and inhibit PG synthesis. By contrast, IL-1 beta and IFN gamma have opposite effects on IL-8, IL-10 and stromelysin productions. These effects are not reversed by L-NMMA, suggesting that NO is not the principal mediator involved in responses of chondrocytes to IFN gamma. [less ▲]

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See detailControl of perimenstrual flares of perioral dermatitis by isotretinoin
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Journal of Dermatological Treatment (2000), 11

BACKGROUNDS: Some cases of perioral dermatitis (POD) appear in young women after the interruption of oral contraception. Perimenstrual POD flares may also occur. Blue-brown, post-inflammatory macules and ... [more ▼]

BACKGROUNDS: Some cases of perioral dermatitis (POD) appear in young women after the interruption of oral contraception. Perimenstrual POD flares may also occur. Blue-brown, post-inflammatory macules and atrophic scarring often persist. Conventional treatment modalities include topical and oral tetracyclines, topical metronidazole and oral contraceptives. However, such therapies mau fail or offer only transient results. Isotretinoin efficacy was reported in a patient with difficult-to-treat POD. METHODS: We studied the outcome of a 6-month course of isotretinoin with a 1-year follow-up in 14 women suffering from chronic or recurrent POD refractory to or dependent on long-term conventional treatments. The isotretinoin dosing regiments were based on acne management guidelines. RESULTS: At 1-year follow-up, 12 of 14 (85,7 %) of the women remained free of POD recurrences, one patient (7,1 %) experienced a significant improvement, and one patient (7,1 %) showed only transient improvement during therapy, and rapidly relapsed after completing two 6-month treatment courses. The muco-cutaneous side effects were similar to those already known for isotretinoin. No other adverse effects occured. CONCLUSION: Isotretinoin represents a valuable therapeutic alternative for women suffering from chronic or recurrent POD refractory to or dependent on conventional treatment options. [less ▲]

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See detailQue pense l’élève de la leçon qu’il vient de vivre ?
Piéron, Maurice ULg; Delfosse, Catherine; Ledent, Maryse et al

in Revue de l'Education Physique (2000), 40(3), 119-129

S'intéresser aux avis des acteurs de la relation pédagogique sur ce qu'ils vivent en classe représente une démarche particulièrement utile pour mieux apprécier la signification des comportements qu'ils ... [more ▼]

S'intéresser aux avis des acteurs de la relation pédagogique sur ce qu'ils vivent en classe représente une démarche particulièrement utile pour mieux apprécier la signification des comportements qu'ils ont adoptés. Il est clair qu'à l'issue d'une leçon d'éducation physique, il est hautement souhaitable que les élèves éprouvent autant de satisfaction que possible. Une estimation globale de satisfaction doit être complétée de perceptions plus spécifiques relatives à l'intensité de la leçon, aux sentiments de compétence en relation avec ce qui fut réalisé, aux corrections reçues, au progrès réalisé, au sentiment de s'être donné à fond, de s'être amusé et d'avoir prêté attention aux interventions de l'enseignant. [less ▲]

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See detailLa pseudogestation chez la chèvre, facteur d'infertilité
Zarrouk, Anissa; Drion, Pierre ULg; Beckers, Jean-François ULg

in Annales de Médecine Vétérinaire (2000), 144

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See detail“Cross-Cultural Dialogues with Greek Classics: Walcott’s The Odyssey and Soyinka’s The Bacchae of Euripides.”
Bada, Valérie ULg

in Ariel : A Review of International English Literature (2000)

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See detailCharacterization of embryos derived from calf oocytes: kinetics of cleavage, cell allocation to inner cell mass, and trophectoderm and lipid metabolism.
Majerus, V.; Lequarré, Anne-Sophie ULg; Ferguson, E. M. et al

in Molecular Reproduction and Development (2000), 57(4), 346-52

Embryos derived from calf oocytes were compared with adult cow oocyte-derived embryos (1) by studying the kinetics of embryo development using time-lapse cinematography (2) by evaluating the ratio between ... [more ▼]

Embryos derived from calf oocytes were compared with adult cow oocyte-derived embryos (1) by studying the kinetics of embryo development using time-lapse cinematography (2) by evaluating the ratio between inner cell mass (ICM) and trophectoderm (TE) cells in blastocysts (3) by measuring the triglyceride content of the blastocysts. The rate of calf oocyte-derived embryos reaching the blastocyst stage was reduced (26 vs. 46% for adult derived embryos). Calf oocyte-derived embryos preferably arrested their development before the 9-cell stage. Those that developed into blastocysts had cleaved earlier to reach the 2-cell or 3-cell stages than embryos that arrested before the 9-cell stage. The 9-cell stage tended to appear later in calf oocyte-derived embryo that reached the blastocyst stage than in adult-derived embryos. This difference became significant at the morula stage. Accordingly, the fourth cell cycle duration was longer for calf oocyte-derived embryos. Day 8 blastocysts from both sources had similar total cell numbers (calf: 89 +/- 20; cow: 100 +/- 30) and cell distribution between TE and ICM. The triglyceride content of day 7 blastocysts was similar for both sources (64 +/- 15 vs. 65 +/- 6 ng/embryo, respectively). In conclusion, calf oocyte-derived embryos are characterized by a higher rate of developmental arrest before the 9-cell stage and by a longer lag phase preceding the major onset of embryonic genome expression. These changes might be related to insufficient "capacitation" of the calf oocyte during follicular growth. Despite these differences, modifications in the quality of the resulting blastocysts were not detected. [less ▲]

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See detailDielectronic structure of 2l-1s Transitions of Multicharged Ions of Argon with nuclear charges Z = 10 - 17
Biémont, Emile ULg; Quinet, Pascal ULg; Faenov, A.Ya et al

in Physica Scripta (2000), 61

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See detailMedium-size droplets of methyl ricinoleate are reduced by cell-surface activity in the γ-decalactone production by Yarrowia lipolytica
Waché, Y.; Bergmark, K.; Courthaudon, J.-L. et al

in Letters in Applied Microbiology (2000), 30(3), 183-187

Size of methyl ricinoleate droplets during biotransformation into γ-decalactone by Yarrowia lipolytica was measured in both homogenized and non-homogenized media. In non-homogenized but shaken medium ... [more ▼]

Size of methyl ricinoleate droplets during biotransformation into γ-decalactone by Yarrowia lipolytica was measured in both homogenized and non-homogenized media. In non-homogenized but shaken medium, droplets had an average volume surface diameter d 32 of 2.5 μm whereas it was 0.7 μm in homogenized and shaken medium. But as soon as yeast cells were inoculated, both diameters became similar at about 0.7 μm and did not vary significantly until the end of the culture. The growth of Y. lipolytica in both media was very similar except for the lag phase which was lowered in homogenized medium conditions. [less ▲]

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See detailDeletion of the 5'-ABL region: a recurrent anomaly detected by fluorescence in situ hybridization in about 10% of Philadelphia-positive chronic myeloid leukaemia patients.
Herens, Christian ULg; Tassin, Françoise ULg; Lemaire, Véronique ULg et al

in British Journal of Haematology (2000), 110(1), 214-6

Inclusion of the BCR-ABL ES probe in routine cytogenetics led to the identification of a subgroup of Philadelphia positive (Ph+) chronic myeloid leukaemia patients characterized by a 5'-ABL deletion. This ... [more ▼]

Inclusion of the BCR-ABL ES probe in routine cytogenetics led to the identification of a subgroup of Philadelphia positive (Ph+) chronic myeloid leukaemia patients characterized by a 5'-ABL deletion. This anomaly was observed in 5/51 cases (9.8%). Cytological and clinical data suggest that the 5'-ABL deletion may be associated with dysplastic features of polymorphonuclear cells and metamyelocytes and a short chronic phase duration. [less ▲]

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See detailEvidence for expression of some Microtubule-associated Protein 1B in neurons as a plasma membrane glycoprotein.
Franzen, Rachelle ULg; Tanner, Sandy; Jaffe, Howard et al

in Journal of Neurochemistry (2000), 75

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See detailLa maladie du hêtre : catastrophe écologique ou accident de la nature.
Rondeux, Jacques ULg

in Parcs & Réserves (2000), 55(3-4), 49

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See detail"J'ai deux ‘amours’…"
Dejasse, Erwin ULg

in Art&Fact (2000), 19

The representations of Paris into the comic "Adèle Blanc-Sec" by Jacques Tardi.

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See detailFirst experimental evidence of alluaudite-like phosphates with high Li-content: the (Na1-xLix)MnFe2(PO4)3 series (x = 0 to 1).
Hatert, Frédéric ULg; Keller, Paul; Lissner, Falk et al

in European Journal of Mineralogy (2000), 12

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See detailA numerically efficient data analysis method with error map generation
Rixen, M.; Beckers, Jean-Marie ULg; Brankart, J. M. et al

in Ocean Modelling (2000), 2

The variational inverse model (VIM) for data analysis was already shown to be statistically equivalent to objective analysis (OA) provided the covariance function for the OA and the VIM reproducing kernel ... [more ▼]

The variational inverse model (VIM) for data analysis was already shown to be statistically equivalent to objective analysis (OA) provided the covariance function for the OA and the VIM reproducing kernel are identical. The VIM, however does not allow a direct derivation of the error field associated with the analysis. The purpose of the paper is to extend the one to one correspondance between the two analysis shemes by proposing a heuristic statistical error expression for the VIM. The numerical efficiency on analysis and error map generation of both methods is compared on quasi-synoptic and climatological data sets. It is shown that the VIM analysis and error map generation offers interesting numerical skills in both case studies. [less ▲]

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See detailNew strictosidine beta-glucosidase from Strychnos mellodora
Brandt, Viviane; Geerlings, Arjan; Tits, Monique ULg et al

in Plant Physiology & Biochemistry (2000), 38(3), 187-192

A stable strictosidine glucosidase was isolated from dried powdered material of Strychnos mellodora. The kinetic parameters Km and Vmax of the purified glucosidases from catharanthus roseus and S ... [more ▼]

A stable strictosidine glucosidase was isolated from dried powdered material of Strychnos mellodora. The kinetic parameters Km and Vmax of the purified glucosidases from catharanthus roseus and S. mellodora towards strictosidine, dolichantoside and palicoside were determined and compared. [less ▲]

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See detailTubal versus uterine placentation: similar HLA-G expressing extravillous cytotrophoblast invasion but different maternal leukocyte recruitment
Proll, J.; Bensussan, A.; Goffin, Frédéric ULg et al

in Tissue Antigens (2000), 56(6), 479-491

The nonclassical HLA-G class I gene is expressed by extravillous cytotrophoblast that invades decidua in uterine pregnancy, suggesting that it may contribute to the immunological mechanisms that protect ... [more ▼]

The nonclassical HLA-G class I gene is expressed by extravillous cytotrophoblast that invades decidua in uterine pregnancy, suggesting that it may contribute to the immunological mechanisms that protect the fetus against maternal alloimmune response and/or pathogen infections. We first addressed the question of whether HLA-G expression was dependent on maternal tissue environment by comparing uterine and ectopic tubal pregnancies. Using HLA-G-specific mAb on placental cryosections, we found by immunohistochemistry that all subtypes of extravillous cytotrophoblast similarly expressed HLA-G in pregnant tubes, demonstrating that its expression was independent of the site of implantation. We next compared by immunohistochemistry the phenotype of maternal leukocytes recruited in both pregnant tissues. In contrast to decidua, pregnant tubes were characterized firstly, by the lack of natural killer (NK) cells and of cells expressing CD94 receptor specific for HLA-E, secondly, by a prominent increase of CD8+ T cells, dendritic cells, and macrophages, the latter co-expressing the LIR1/ILT2 killer immunoglobulin-like receptor (KIR), and finally, by the presence of cells expressing LIR2/ILT4 KIR or BY55 NK receptors, known to bind to HLA-G. Such cell types may favor a unique innate defense in pregnant tubes. These observations also suggest that trophoblast HLA-G expression does not influence the recruitment of particular maternal leukocytes in pregnant tissues. [less ▲]

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See detailRole of Substance P and Tachykinin Receptor Antagonists in Citric Acid-Induced Cough in Pigs
Moreaux, B.; Nemmar, A.; Vincke, G. et al

in European Journal of Pharmacology (2000), 408(3), 305-312

The purpose of this work was to investigate the role of tachykinins in cough induced by citric acid (0.8 M) in pigs. With this object, we have studied the effect of citric acid on substance P content in ... [more ▼]

The purpose of this work was to investigate the role of tachykinins in cough induced by citric acid (0.8 M) in pigs. With this object, we have studied the effect of citric acid on substance P content in the tracheo-bronchial tree and the effects of substance P and of tachykinin receptor antagonists on citric acid-induced cough. Citric acid exposure significantly increased substance P concentration in both broncho-alveolar and tracheal lavage fluids, while it decreased significantly the substance P content in tracheal mucosa. Substance P did not elicit cough, but significantly potentiated the citric acid-induced cough frequency. Tachykinin NK(1), NK(2) or NK(3) receptor antagonists, SR 140333 (nolpitantium), SR 48968 (saredutant) and SR 142801 (osanetant), respectively, significantly inhibited citric acid-induced cough. The same inhibitory effect of tachykinin receptor antagonists was observed, when substance P was nebulised before citric acid challenge. We conclude that citric acid induces in pigs a release of substance P in the tracheo-bronchial tree, which plays a sensitising role on the cough reflex. The involvement of tachykinin NK(1), NK(2), NK(3) receptors are also demonstrated in this reflex. [less ▲]

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See detailLa pleuropneumonie contagieuse bovine
Linden, Annick ULg; Desmecht, Daniel ULg

in Vlaams Diergeneeskundig Tijdschrift (2000), 69

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See detailSeasonal changes of pCO(2) over a subantarctic Macrocystis kelp bed
Delille, Bruno ULg; Delille, D.; Fiala, M. et al

in Polar Biology (2000), 23(10), 706-716

The partial pressure of carbon dioxide (pCO(2)), calculated from pH and total alkalinity measurements. was monitored together with chlorophyll a and bacterioplankton biomass in shallow coastal water ... [more ▼]

The partial pressure of carbon dioxide (pCO(2)), calculated from pH and total alkalinity measurements. was monitored together with chlorophyll a and bacterioplankton biomass in shallow coastal water located inside and outside a giant kelp bed (Macrocystis pyrifera) situated in the Kerguelen Archipelago, Southern Ocean. In spite of large changes over a short time-scale pCO(2) variations over the year are large and exhibit a seasonal pattern in which the different stages of the annual biological turnover are well marked. The overall pattern of pCO(2) variations is related to biological activity (development of both photosynthesis and respiration) during almost the whole year. However, physical and thermodynamical constraints exert a strong influence on pCO(2) at meso time-scale (10 days) and/or when biological activity is weak. Macrocystis acts to maintain pCO(2) below saturation almost the whole year and large undersaturations (pCO(2) as low as 20 mu atm) were observed within the kelp bed. Furthermore, primary production of Macrocystis covers a period of 8 similar to 9 months a year from winter to late summer and the kelp bed seems to favour the spring phytoplanktonic bloom. The buffer factor beta indicates that, outside the kelp bed, inorganic carbon dynamics are mainly influenced by air-sea exchange and photosynthesis without calcification. Inside the kelp bed. beta suggests calcification by the epiphytic community. [less ▲]

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See detailA survey on staging and treatment in uterine cervical carcinoma in the Radiotherapy Cooperative Group of the European Organization for Research and Treatment of Cancer
Coucke, Philippe ULg; Maingon, P; Ciernik, I et al

in Radiotherapy & Oncology (2000), 54

Abstract Background: The treatment outcome of advanced stage uterine cervical carcinoma remains unsatisfactory. In order to elaborate a novel trial within The Radiotherapy Cooperative Group (RCG) of the ... [more ▼]

Abstract Background: The treatment outcome of advanced stage uterine cervical carcinoma remains unsatisfactory. In order to elaborate a novel trial within The Radiotherapy Cooperative Group (RCG) of the European Organization for Research and Treatment of Cancer (EORTC), we conducted a survey in 1997±1998 to determine the variability of pre-treatment assessment and treatment options. The variability of choosing surgery, de®ned radiation therapy techniques and chemotherapy are investigated, as well as the center's choices of future treatment strategies. Methods: Fifty two of 81 RCG centers from the RCG have participated in the survey. As one would expect, there is a large variation in the techniques used for pretreatment evaluation and treatment options. There is no `standard' for reporting acute and late side effects. Chemotherapy is used neither systematically nor uniformly, and some centers continue to use neadjuvant chemotherapy modalities. Results: Furthermore, the survey reveals that there is a strong demand for the reduction of overall treatment-time, for clinical investigation of novel combined modality treatment strategies, especially chemo±radiation therapy, and also for the use of new radiation sensitizers. Conclusion:We conclude that a more homogeneous approach to the pretreatment evaluation as well as treatment techniques is required in order to allow adequate quality control in any future trial of the RCG in the EORTC.q2000 Elsevier Science Ireland Ltd. All rights reserved. [less ▲]

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See detail'Flexihealth', un nécessaire équilibre entre contraintes de flexibilité et bine-être des travailleurs
De Zanet, Fabrice ULg; Vandenberghe, Christian; Bossut, Muriel ULg et al

in Point d'appui T E F (2000), 2

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See detailEcoliers et apprentis-lecteurs : quelle est la motivation des enfants en première primaire ?
Hindryckx, Geneviève ULg; Lafontaine, Annette ULg; Schockert, C.

in Point sur la Recherche en Education (Le) (2000)

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See detailMatrix metalloproteinase-3 serum levels are correlated with disease activity and predict clinical response in rheumatoid arthritis
Ribbens, Clio ULg; Andre, Béatrice ULg; Jaspar, J. M. et al

in Journal of Rheumatology (2000), 120(1), 888-893

OBJECTIVE: To demonstrate that serum matrix metalloproteinase-3 (MMP-3) is a variable associated with disease activity and with the response to treatment in rheumatoid arthritis (RA). METHODS: Serum MMP-3 ... [more ▼]

OBJECTIVE: To demonstrate that serum matrix metalloproteinase-3 (MMP-3) is a variable associated with disease activity and with the response to treatment in rheumatoid arthritis (RA). METHODS: Serum MMP-3 levels were measured and compared to biological and clinical disease activity variables in 20 patients with active RA assessed serially during a one year prospective open label trial with methotrexate or tenidap. RESULTS: MMP-3 levels were significantly correlated with C-reactive protein (CRP) and interleukin 6 serum levels as well as with the disease activity score (DAS), not only at start in untreated patients but also during the 12 month followup period in both treated groups. Early changes (after 0.5, 1, 2, or 3 months) in MMP-3 levels were significantly associated with change in DAS observed 4 to 6 months later. CONCLUSION: In addition to CRP, a systemic marker of inflammation, serum MMP-3 may serve as a consistent synovial derived marker of RA disease activity, early changes of which predict disease outcome. [less ▲]

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See detailKinetic and spectroscopic characterization of native and metal-substituted beta-lactamase from Aeromonas hydrophila AE036.
Hernandez Valladares, M.; Kiefer, M.; Heinz, U. et al

in FEBS letters (2000), 467(2-3), 221-5

Two metal ion binding sites are conserved in metallo-beta-lactamase from Aeromonas hydrophila. The ligands of a first zinc ion bound with picomolar dissociation constant were identified by EXAFS ... [more ▼]

Two metal ion binding sites are conserved in metallo-beta-lactamase from Aeromonas hydrophila. The ligands of a first zinc ion bound with picomolar dissociation constant were identified by EXAFS spectroscopy as one Cys, two His and one additional N/O donor. Sulfur-to-metal charge transfer bands are observed for all mono- and di-metal species substituted with Cu(II) or Co(II) due to ligation of the single conserved cysteine residue. Binding of a second metal ion results in non-competitive inhibition which might be explained by an alternative kinetic mechanism. A possible partition of metal ions between the two binding sites is discussed. [less ▲]

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See detail"Ant'Phipoda", the reference centre for Antarctic crustaceans: A tool for developing and managing Antarctic marine biodiversity information
De Broyer, Claude; Duchesne, Paul-André; Vander Linden, Charles et al

in Polish Archives for Hydrobiology (2000), 47

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See detailLa mémoire de travail : une approche neuropsychologique et par imagerie cérébrale
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Thérapie (2000), 55(4), 455-460

The working memory model proposed by Baddeley and Hitch has frequently been used in cognitive psychology and neuropsychological studies. This model consists of several interacting components, responsible ... [more ▼]

The working memory model proposed by Baddeley and Hitch has frequently been used in cognitive psychology and neuropsychological studies. This model consists of several interacting components, responsible for the storage and processing of the information stored in working memory. Many neuropsychological and functional imagery data are consistent with that formulation of working memory. Moreover, many cognitive tasks have been specifically designed to explore particular aspects of working memory functioning. Taken as a whole, these data confirm that the working memory model remains a useful theoretical framework to explore memory functioning both in normal subjects and in pathological conditions. [less ▲]

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See detailUn modèle de gestion informatisé pour les plantations d'épicéa commun en Ardenne belge
Lejeune, Philippe ULg; Thibaut, André; Pauwels, Dominique

in Les cahiers forestiers de Gembloux (2000), (24), 26

Norway spruce (Picea abies (L.) Karst.) is the first forest species devoted to production in the Wallonian region. Many private and public foresters have to face management problems for these stands ... [more ▼]

Norway spruce (Picea abies (L.) Karst.) is the first forest species devoted to production in the Wallonian region. Many private and public foresters have to face management problems for these stands : rotation length, definition of thinning type, harvesting scheduling, future income and profitability estimation, ... The management model presented in this article can give some answers to these questions. It is made of two components : on one hand, a growth model predicts stand growth in connection with site index and silvicultural parameters, and, on the other hand several modules compute silvicultural indicators (stability index, mortality rate, assortments, ...) and financial indicators (prediction of future incomes and profitability). The management model allows to test and compare in a flexible way different scenarios applicable to stands described by their initial stage (number of stems and basal area per hectare, dominant height). These tools are integrated in a spreadsheet application using Excel TM, which makes it very easy to use by the forest manager who wants to base his managment on objective criteria. [less ▲]

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See detailKantvilasia (Lecanorales, Ectolechiaceae), a new foliicolous lichen genus from Tasmania
McCarthy, P.M.; Elix, J.A.; Sérusiaux, Emmanuël ULg

in Lichenologist (2000), 32

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See detailLa gestion integrée des déchets solides de Kigali (Rwanda)
Culot, Marc ULg; Nzeyimana, François

in Echos du COTA (2000), (87), 6-9

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See detailMission du team belge au Kosovo: science et justice à la rencontre du drame humain. Premiers résultats
BEAUTHIER, Jean-Pol; Boxho, Philippe ULg; CREVECOEUR, Jean-Marie et al

in Revue de Biométrie humaine et d'Anthropologie (2000)

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See detailBegian guidelines concerning drug induced alteration of coagulation and central neuraxial anesthesia
Brichant, Jean-François ULg; De Kock, Marc; De Mey, J. C. et al

in Acta Anaesthesiologica Belgica (2000), 51

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See detailComment évolue la motivation pour l'école et pour la lecture des enfants entre la 1re et la 3e année primaire
Hindryckx, Geneviève ULg; Schockert, Catherine

in Point sur la Recherche en Education (Le) (2000), 14

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See detailLes encéphalopathies à herpèsvirus bovins
Meyer, Gilles; D'Offay, Jean; Thiry, Etienne ULg

in Point Vétérinaire (2000), 31

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See detailLa mesure de l'efficacite therapeutique, etape essentielle dans la medecine factuelle.
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(4), 206-10

Evidence-based medicine relies on the results from clinical trials. We will describe the various modes of expression of the results (absolute risk reduction, relative risk reduction, odds ratios, number ... [more ▼]

Evidence-based medicine relies on the results from clinical trials. We will describe the various modes of expression of the results (absolute risk reduction, relative risk reduction, odds ratios, number needed to treat to avoid one event,...) and we will insist upon the clinical significance and the pitfalls in the interpretation of these various indices of therapeutic efficacy. [less ▲]

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See detailL'infection de la chèvre par l'herpèsvirus caprin de type 1
Engels, M.; Thiry, Etienne ULg

in Point Vétérinaire (2000), 31

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See detailLandscape fragmentation assessment using a single measure.
Bogaert, Jan ULg; Van Hecke, P; Salvador-Van Eysenrode, D et al

in Wildlife Society Bulletin (2000), 28(4), 875-881

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See detailThe role of lateral occipitotemporal junction and area MT/V5 in the visual analysis of upper-limb postures
Peigneux, Philippe ULg; Salmon, Eric ULg; Van der Linden, Martial ULg et al

in Neuroimage (2000), 11(6), 644-655

Humans, like numerous other species, strongly rely on the observation of gestures of other individuals in their everyday life. It is hypothesized that the visual processing of human gestures is sustained ... [more ▼]

Humans, like numerous other species, strongly rely on the observation of gestures of other individuals in their everyday life. It is hypothesized that the visual processing of human gestures is sustained by a specific functional architecture, even at an early prelexical cognitive stage, different from that required for the processing of other visual entities. In the present PET study, the neural basis of visual gesture analysis was investigated with functional neuroimaging of brain activity during naming and orientation tasks performed on pictures of either static gestures (upper-limb postures) or tridimensional objects. To prevent automatic object-related cerebral activation during the visual processing of postures, only intransitive postures were selected, i.e., symbolic or meaningless postures which do not imply the handling of objects. Conversely, only intransitive objects which cannot be handled were selected to prevent gesture-related activation during their visual processing. Results clearly demonstrate a significant functional segregation between the processing of static intransitive postures and the processing of intransitive tridimensional objects. Visual processing of objects elicited mainly occipital and fusiform gyrus activity, while visual processing of postures strongly activated the lateral occipitotemporal junction, encroaching upon area MT/V5, involved in motion analysis. These findings suggest that the lateral occipitotemporal junction, working in association with area MT/V5, plays a prominent role in the high-level perceptual analysis of gesture, namely the construction of its visual representation, available for subsequent recognition or imitation. (C) 2000 Academic Press. [less ▲]

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See detailCancer in Transplant Recipients
Detry, Olivier ULg; Honore, Pierre ULg; Meurisse, Michel ULg et al

in Transplantation Proceedings (2000), 32(1), 127

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See detailQuando il tempo è sospeso: individuo e famiglia nell’anoressia mentale
D'Amore, Salvatore ULg

in Ecologia della Mente (2000), 1

Discusses anorexia nervosa as a complex syndrome in which sociocultural, familial, and individual components are interconnected. Based on their own work with anorexic patients and their families, the ... [more ▼]

Discusses anorexia nervosa as a complex syndrome in which sociocultural, familial, and individual components are interconnected. Based on their own work with anorexic patients and their families, the present authors examine the familial aspects of anorexia at an interactional level and a mythical level. The importance of a 3-generational perspective on anorexia is emphasized. The case study of a 17-yr-old female student with bulimic anorexia is discussed with regard to family dynamics and myths and the sculpting of the present and the future. [less ▲]

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See detailPercolation as a model for informetric distributions: fragment size distribution characterised by Bradford curves
Bogaert, Jan ULg; Rousseau, R; Van Hecke, P

in Scientometrics (2000), 47(2), 195-206

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See detailQuelles stratégies pour favoriser le retour au travail du patient lombalgique ? Enseignement des expériences étrangères
Mairiaux, Philippe ULg

in Médecine du Travail & Ergonomie= Arbeidsgezondheidszorg & Ergonomie (2000), 37(1), 5-12

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See detailPolitique et usage des manuels scolaires en mathématiques et en sciences
Monseur, Christian ULg; Demeuse, Marc ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), (3-4), 177-183

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See detailActualites therapeutiques 2000.
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(9), 852-61

The most important drugs registered and/or launched in Belgium during the last year in the various disciplines of internal medicine will be briefly described. The originality of each molecule as well as ... [more ▼]

The most important drugs registered and/or launched in Belgium during the last year in the various disciplines of internal medicine will be briefly described. The originality of each molecule as well as its modalities of appropriate use in clinical practice will be emphasized. [less ▲]

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See detailInteractions between gellan gum and other polysaccharides.
Blecker, Christophe ULg; Razafindralambo, Hary ULg; Paquot, Michel ULg

in Czech Journal of Food Sciences (2000), 18

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See detailL'évaluation externe en lecture menée à l'entrée en 3e secondaire : morceaux choisis
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), (1-2), 7-11

En octobre 1998, une évaluation externe en lecture s'est déroulée dans un échantillon représentatif de classes de 3e année de l'enseignement secondaire en Communauté française de Belgique. A cette ... [more ▼]

En octobre 1998, une évaluation externe en lecture s'est déroulée dans un échantillon représentatif de classes de 3e année de l'enseignement secondaire en Communauté française de Belgique. A cette occasion, on a non seulement évalué dans quelle mesure les élèves maîtrisent certaines des compétences essentielles reprises dans les socles, mais aussi tenté de comprendre les rapports complexes que les adolescents entretiennent avec le monde de l'écrit. [less ▲]

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See detailGEOPHYSICAL INVESTIGATIONS OF SEISMICALLY INDUCED SURFACE EFFECTS: CASE STUDY OF A LANDSLIDE IN THE SUUSAMYR VALLEY, KYRGYZSTAN
Havenith, Hans-Balder ULg; Jongmans, D.; Abdrakhmatov, K. et al

in Surveys in Geophysics (2000), 21

In summer 1998, a geophysical survey including seismic profiles and electrical tomography has been carried out in the Suusamyr valley, Kyrgyzstan. The scope was to investigate surface effects induced by ... [more ▼]

In summer 1998, a geophysical survey including seismic profiles and electrical tomography has been carried out in the Suusamyr valley, Kyrgyzstan. The scope was to investigate surface effects induced by the Ms = 7.3 Suusamyr earthquake, the 19th of August, 1992. In this paper, special attention is paid to the case study of a debris slide triggered by the earthquake. Seismic data are analysed by P-wave refraction technique and by surface wave inversion. Electrical tomographic profiles are processed by 2D-inversion. Using geotechnical and geological information, P-velocity models and resistivity sections are interpreted in terms of geological materials, in order to build a geological 3D model. On the basis of the latter, we carried out static finite element computations as well as static and pseudo-static calculations with Janbu’s method. Newmark displacement was computed, considering or not the influence of the shallow soft deposits. The results are compared to the real displacement observed in the field and conclusions are drawn about the mechanism of the landslide. [less ▲]

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See detailEntre stalle et prie-Dieu. La religieuse liégeoise en prière
Henneau, Marie-Elisabeth ULg

in Revue de l'Histoire des Religions (2000), 217(3), 327-344

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See detailÀ la recherche du Candide liégeois
Droixhe, Daniel ULg

in Australian Journal of French Studies (2000), 37(2), 127-164

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See detailEffects of propofol on endothelial cells subjected to a peroxynitrite donor (SIN-1).
Mathy, Marianne ULg; Mouithys-Mickalad, Ange ULg; Kohnen, S. et al

in Anaesthesia (2000), 55(11), 1066-71

We investigated the effect of propofol on endothelial cells subjected to the peroxynitrite (ONOO-) donor 3-morpholino sydnonimine (SIN-1). Cells were incubated overnight with 0.5, 1.0 or 2.0 mM SIN-1 ... [more ▼]

We investigated the effect of propofol on endothelial cells subjected to the peroxynitrite (ONOO-) donor 3-morpholino sydnonimine (SIN-1). Cells were incubated overnight with 0.5, 1.0 or 2.0 mM SIN-1, with or without 10-3 M propofol (Diprivan). Cytotoxicity, assessed by measuring the release of pre-incorporated 51Cr, increased when the concentration of SIN-1 increased, and was significantly decreased by 10-3 M propofol (90%, 78% and 28% of protection against 0.5, 1.0 and 2.0 mM SIN-1, respectively). Cell protection against 1 mM SIN-1 was tested with 0.03-1.0 mM propofol and this was compared to tyrosine, a target molecule for peroxynitrite. Propofol protected cells in a dose-dependent manner (r = 0.98; p < 0.001) and was as effective as tyrosine. Finally, using high-performance liquid chromatography, we demonstrated that propofol reacted with ONOO- more rapidly than did tyrosine, inhibiting nitrotyrosine formation. In the absence of propofol, 3.5 mM ONOO- with 1 mM tyrosine yielded 39.6% nitrotyrosine, but nitrotyrosine was not produced when 5 mM propofol was added. We conclude that propofol protects endothelial cells against the toxicity of ONOO-. The anti-oxidant properties of propofol can be partially attributed to its scavenging effect on peroxynitrite, a property that might be relevant in pathological situations involving a significant contribution of peroxynitrite to tissue damage. [less ▲]

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See detailAutour de Stavelot-Malmedy (VIIe-IXe siècles)
George, Philippe ULg

in Publications de la Section Historique de l'Institut Royal Grand-Ducal de Luxembourg (2000)

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See detailEmissions de vapeur d’eau et bilan azoté lors de l’élevage de porcelets sevrés sur litière accumulée de sciure
Nicks, Baudouin ULg; Laitat, Martine ULg; Vandenheede, Marc ULg et al

in Annales de Zootechnie (2000), 49

Five batches of a total of 180 weaned pigs were reared successively in an experimental room on 30 cm deep litter without cleaning between the batches. The litter was a mixture of sawdust from coniferous ... [more ▼]

Five batches of a total of 180 weaned pigs were reared successively in an experimental room on 30 cm deep litter without cleaning between the batches. The litter was a mixture of sawdust from coniferous and beech trees. Water was added to the Litter every 10 days to lower the dust concentration in the room. The total amounts of sawdust and water used were respectively 21.3 kg per pig and 10.21 per pig. The mean temperature of the litter at 20 cm depth recorded during each of the 5 periods varied from 32.5 degrees C to 41.8 degrees C. The average liveweight of the pigs at the beginning and at the end of the post-weaning period was respectively 7.9 +/- 1.2 kg and 24.5 +/- 4.2 kg. The average daily gain was 392 +/- 87 g. The temperature and the relative humidity of the air inside and outside the experimental room and the ventilation rate were continuously recorded in order to calculate the water vapour emission for each batch. The amount of water vapour produced was significantly correlated to the water consumption of the pigs and reached an average of 1 732 g per pig per day. This amount is 36% greater than the reference used for pigs on slatted floors. This value may be used as a reference to calculate the minimum ventilation rate for piggeries with pigs on sawdust deep litters. The amount of compost produced was 19.9 kg per pig with a dry matter content of 44.7%. The amount of nitrogen in the compost was 231 g per pig which is about 50% lower than the reference used for the slurry. The volatile nitrogen emissions are thus much higher from composts than from slurries [less ▲]

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See detailMelanoma screening: results of the first one-day campaign in Belgium (‘Melanoma Monday’)
Vandaele, M.; Richert, Bertrand ULg; Van der Endt, J. M. et al

in Journal of the European Academy of Dermatology & Venereology (2000), 14

Background: Although the incidence of melanoma is increasing and many informative campaigns have been organized. The general population is still little informed about this tumour. Aims: To organize a ... [more ▼]

Background: Although the incidence of melanoma is increasing and many informative campaigns have been organized. The general population is still little informed about this tumour. Aims: To organize a media campaign, with more relevant information and the opportunity for free skin inspections. Methods: A ‘Task Force’ organized a media campaign in April 1999 and convinced 65% of the Belgian dermatologists to give up 4 h of their time to do free skin examinations for skin cancer on Monday 26 April 1999; it was called ‘Melanoma Monday’. Results: A total 2767 patients were screened. We found 25 melanomas and suspected 59 basal cell carcinomas. In the following 4 weeks another 141 melanomas were found. These 166 melanomas found in one month represent 15 –20% of the total number of melanomas per year in Belgium. Summary: A media campaign with relevant information combined with screening opportunities can lead to the early detection of melanomas in a large number of patients and can continue to alert people at risk in the following weeks. [less ▲]

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See detailLe feuilleton de l'expertise (contradictoire) en matière pénale
Jacobs, Ann ULg

in Information et document juridqiques (2000), (4), 1-2

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See detailGenetic organisation of the lipopolysaccharide O-antigen biosynthesis region of brucella melitensis 16M (wbk).
Godfroid, F.; Cloeckaert, A.; Taminiau, Bernard ULg et al

in Research in Microbiology (2000), 151(8), 655-68

Brucella spp. are Gram-negative, facultative intracellular bacteria that cause a zoonotic world-wide disease. As in other Gram-negative bacteria, its S-LPS (smooth lipopolysaccharide) is a major ... [more ▼]

Brucella spp. are Gram-negative, facultative intracellular bacteria that cause a zoonotic world-wide disease. As in other Gram-negative bacteria, its S-LPS (smooth lipopolysaccharide) is a major determinant of virulence. The Brucella melitensis 16M LPS O-antigen is a homopolymer of 4-formamido-4,6, dideoxymannose. In this study, the previously cloned 14-kb wbk gene cluster was sequenced, and seven open reading frames (ORFs) as well as four insertion sequences were identified. Six of the seven ORFs are homologous to LPS biosynthesis genes from other organisms. The gmd, per and wbkC gene products are predicted to be involved in 4-formamido-4,6,dideoxymannose synthesis. By deletion experiments, we demonstrated that the putative formyltransferase WbkC is absolutely required for the O-side-chain production. The wbkA gene product is similar to several mannosyltransferases and is probably involved in the polymerisation of the B. melitensis O-side-chain. We also identified two genes (wzm and wzt) encoding proteins with high similarity to several two-component ABC (ATP-binding cassette) transporters. Their implication in O-antigen translocation across the inner membrane was confirmed by gene replacement. Finally, no function has been assigned to the wbkB gene either by homology search or functionally, because deletion of wbkB did not interfere with the O-antigen structure. The seven ORFs have a low G + C content, indicating that they might have been acquired by lateral transfer from a progenitor with more A + T rich DNA. [less ▲]

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See detailPhase II study of docetaxel alternating with cisplatin in chemotherapy-naïve patients with advanced non-small cell lung cancer
Mattson, Karin; Vansteenkiste, Johan; Stupp, Roger et al

in Anti-Cancer Drugs (2000), 11

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See detailAvocat et assureur protection juridique : la fin des tensions ?
Paris, Catherine ULg

in Revue Générale des Assurances et des Responsabilités (2000)

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See detailLa prescription de l'action publique
Jacobs, Ann ULg

in Journal des Tribunaux (2000)

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See detailLes composantes d'un management efficace dans le cadre des organisations sportives
Cloes, Marc ULg

in Sport (2000), 172

L'objectif de cet article consiste à réaliser une synthèse des notions abordées par les auteurs du colloque "Initiatives en matière de management du sport" et de fournir un outil permettant aux ... [more ▼]

L'objectif de cet article consiste à réaliser une synthèse des notions abordées par les auteurs du colloque "Initiatives en matière de management du sport" et de fournir un outil permettant aux responsables d'organisatons sportives de s'engager dans une auto-analyse des structures dont ils ont la charge. Pour rappel, le management se définit comme l'action de gérer, de diriger, d'assurer le succès d'une organisation. [less ▲]

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See detailHacia una psicologia integradora : utopia o necesidad ?
Richelle, Marc ULg

in Revista de Psicologia General y Aplicada (2000), 53(4), 581--588

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See detailCalendes et calendriers: du temps cyclique au temps historique
Biémont, Emile ULg

in Ciel (Le) (2000), 62

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See detailLes débuts de l'humanité dans le Prométhée enchaîné d'Eschyle
Renaud, Jean-Michel ULg; Wathelet, Paul ULg

in Uranie : Mythes et Littératures (2000), 9

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See detailAbout the Vacuum UV Photoabsorption Spectrum of Methyl Fluoride (CH3F): the fine structure and its vibrational analysis.
Locht, Robert ULg; Leyh, Bernard ULg; Hoxha, A. et al

in Chemical Physics (2000), 257

The vacuum UV photoabsorption spectrum of CH3F has been recorded between 7 and 24 eV and has been analyzed in detail. Broad and structureless peaks are observed over the entire photon energy range. They ... [more ▼]

The vacuum UV photoabsorption spectrum of CH3F has been recorded between 7 and 24 eV and has been analyzed in detail. Broad and structureless peaks are observed over the entire photon energy range. They are all assigned to transitions to Rydberg states, members of series converging to the 2e-1, 5a-1 and 1e-1 ionization limits. These features are underlying very long series of narrow and weak structures in the range of 10-13.2 eV. Through a continuum subtraction procedure, about 70 lines could clearly be identified. These have been assigned to long vibrational progressions belonging to Rydberg states corresponding to the 2e->3p and 2e->6s/5d configurations. These states are split by a Jahn-Teller distortion. Ab initio calculations lead to a Jahn-Teller stabilization energy of about 0.84 eV. The main features observed in the two bands are assigned to one single long vibrational progression of hcomega=0.160 eV (1290cm-1) related to the C-F Jahn-Teller inactive stretching vibration. The remaining structure is assigned to the low excitation of the Jahn-Teller active vibrational modes, i.e. the bending modes nu5 and nu6 characterized by hcomega5=0.120 eV (970 cm-1) and hcomega6=0.082 eV (660 cm-1). Leaning on the present results and assignments previously reported photoelectron spectroscopic data on CH3F+ [L. Karlsson, R. Jadrny, L. Mattsson, F.T. Chau, K. Siegbahn Phys.Scripta 16 (1977) 225] have been reconsidered and reinterpreted. [less ▲]

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See detailMotivations et apports d'une prise en charge ambulatoire pluridisciplinaire de la santé des adolescents
Bourguignon, Jean-Pierre ULg; Grignard, Sophie ULg; Glowacz, Fabienne ULg et al

in Bulletin d'Education du Patient à sa Maladie (2000), 19(3), 126-129

D’importants problèmes de santé sont identifiés par les professionnels chez les adolescents. Toutefois, ces problèmes de santé ne sont que peu ou pas soulevés par les adolescents eux-mêmes car ils ... [more ▼]

D’importants problèmes de santé sont identifiés par les professionnels chez les adolescents. Toutefois, ces problèmes de santé ne sont que peu ou pas soulevés par les adolescents eux-mêmes car ils consultent peu à ce sujet. En particulier, ils évoquent rarement les aspects psychosociaux des problèmes auxquels ils sont confrontés. Ils fonctionnent dans le clivage entre somatique et psychologique bien que ces deux aspects soient indissociables. Les adolescents sont souvent amenés en consultation par d’autres, dont les parents. Un travail d’identification de la demande réelle de l’adolescent est donc nécessaire pour que celui-ci puisse se mobiliser vers une prise en charge. La confidentialité est cruciale de même que le respect de l’adolescent, ainsi que la reconnaissance de ses craintes et des limites qu’il met à l’accès aux informations par l’anamnèse et l’examen clinique. Il appartient au médecin de lire la demande de l’adolescent dans un double registre, à la fois somatique et psychique et de resituer cette demande dans le contexte de vie particulier à l’adolescent. Aussi, la lecture de la demande intégrera non seulement les problèmes invoqués par l’adolescent mais aussi ceux relevés par l’anamnèse et l’examen clinique. Une telle lecture peut prendre du temps pour les intervenants de santé mais aussi pour l’adolescent, avant qu’il n’aboutisse à l’émergence de sa demande et, dès lors, à une demande de prise en charge. Celle-ci devra parfois faire appel à une équipe spécifique et pluridisciplinaire telle que celle où collaborent les auteurs du présent article, au Centre de Santé de l’Adolescent à Liège. [less ▲]

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See detailL'opération sources en Belgique : premières analyses statistiques des résultats et légitimité des cartes "nitrates".
Wattecamps, J. M.; Bernier, Jacques; De Backer, Louis et al

in Hydrological Sciences Journal = Journal des Sciences Hydrologiques (2000), 45(1), 43-60

L'opération sources du WWF (Worldwide Fund for Wildlife) est une action éducative de sensibilisation à la qualité des eaux souterraines. Elle implique principalement les élèves de cinquième et sixième ... [more ▼]

L'opération sources du WWF (Worldwide Fund for Wildlife) est une action éducative de sensibilisation à la qualité des eaux souterraines. Elle implique principalement les élèves de cinquième et sixième primaires de Belgique. Depuis 1994, des centaines de dosages des ions nitrates ont été effectués dans un grand nombre de sources et de puits à l'aide de bandelettes colorimétriques. A l'issue de chaque campagne, les points d'eau surveillés ont été reportés sur une carte de Belgique où leur couleur indique leur qualité eu égard à la concentration en nitrates. L'objectif pédagogique étant atteint, la validation de ces cartes en tant qu'image de la réalité pose le problème de la vérification du lien entre la concentration réelle (mg l-1) du point d'eau visité et sa couleur sur la carte. A cette fin, des vérifications ont été réalisées sur 308 points d'eau choisis au hasard dans l'ensemble des sources et puits visités. L'analyse statistique révèle que la relation entre le test colorimétrique et le contrôle réalisé en laboratoire est hautement significative. Ce résultat justifie des investigations ultérieures, notamment la mobilisation de l'information régionale pour la qualification d'un point d'eau peu surveillé et la comparaison des cartes dans le temps. [less ▲]

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See detailEvaluating risk in unstable angina: role of pharmacological stress echocardiography.
Pierard, Luc ULg

in European heart journal (2000), 21(13), 1041-3

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See detailLe Peuplier
Jourez, Benoît ULg; Quin, Jean-Philippe; Mertens, Patrick

in Courrier du Bois (2000), 40(131), 11-16

Essence de production par excellence, le peuplier revêt une importance économique non négligeable. L'extension de sa culture basée sur les nouveaux cultivars, la qualité de son bois et son aptitude à la ... [more ▼]

Essence de production par excellence, le peuplier revêt une importance économique non négligeable. L'extension de sa culture basée sur les nouveaux cultivars, la qualité de son bois et son aptitude à la transformation, en ont fait une essence qui a pris de l'importance dans certaines branches de l'industrie du bois. [less ▲]

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See detailLe controle glycemique chez le patient diabetique. Recommandations apres les etudes DCCT et UKPDI.
Paquot, Nicolas ULg; Scheen, André ULg; Lefebvre, Pierre ULg

in Revue Médicale de Liège (2000), 55(5), 372-5

Diabetes mellitus is a chronic disorder characterized by microvascular and cardiovascular complications that substantially increase the morbidity and mortality associated with the disease. Several studies ... [more ▼]

Diabetes mellitus is a chronic disorder characterized by microvascular and cardiovascular complications that substantially increase the morbidity and mortality associated with the disease. Several studies showed the association between the complications of diabetes and elevated blood glucose levels. Clinical trials have also demonstrated that treatment that lowers blood glucose reduces the risks of diabetic complications (mainly microvascular complications). The control of diabetes is assessed by frequent measurements of HbA1c. A reasonable goal in type 1 diabetes is a value of HbA1c < or = 7.2%. In type 2 diabetes, the optimal goal is a value of HbA1c < or = 6.5%, but a value < or = 8% seems to be an acceptable goal in these patients. [less ▲]

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See detailSomatic embryogenesis of Panax ginseng in liquid cultures: a role for polyamines and their metabolic pathways
Kevers, Claire ULg; Le Gal, Nathalie; Monteiro, Marta et al

in Plant Growth Regulation (2000), 31(3), 209-214

A callus with embryogenic capacity was generated from root sections of Panax ginseng and used as an inoculum source for embryogenic liquid cultures in a three-step process: - a suspension culture of cell ... [more ▼]

A callus with embryogenic capacity was generated from root sections of Panax ginseng and used as an inoculum source for embryogenic liquid cultures in a three-step process: - a suspension culture of cell aggregates in the presence of an auxin/cytokinin mixture, - an induction medium containing auxin only (for 5 to 30 days), - a regeneration medium containing cytokinin only (for one month). Up to 25 embryos were recovered per 2.5 g of aggregates in these conditions. Incorporation of polyamines or their precursors arginine and ornithine into either the induction or regeneration media increased the number of embryos produced by up to 4 times. Inhibitors of both biosynthesis and biodegradation of polyamines reduced the number of embryos. These results support earlier findings of the role of polyamines in the process of somatic embryogenesis. The success of these liquid cultures opens up the possibility of producing somatic embryos of Panax ginseng in bioreactors. [less ▲]

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See detailPour concevoir et déployer des dispositifs d'accompagnement d'équipes éducatives dans l'élaboration de pratiques collectives
Mouvet, Bernadette ULg; Lenoir, Anne-Sophie; Massart, Valérie ULg et al

in Point sur la Recherche en Education (Le) (2000), 17

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See detailLithics in Belgium. Some Current Research Trends
Rots, Veerle ULg; Vermeersch, Pierre

in Lithic Technology (2000), 25(2), 76-79

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See detailLa variation de l’équilibre glycémique (mais pas du poids) est corrélée positivement à la modification du risque cardiovasculaire absolu chez le patient diabétique
Hadjadj, Samy; Guilloteau, Gérard; Weekers, Laurent ULg et al

in Archives des Maladies du Coeur et des Vaisseaux (2000), 93(8), 1033-1036

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See detailCroissance et rentabilité des plantations de douglas en Région wallonne.
Lejeune, Philippe ULg; Hebert, Jacques ULg; Rondeux, Jacques ULg

in Silva Belgica (2000), 107(1), 6-15

Considéré par beaucoup de sylviculteurs européens comme une essence d'avenir, le douglas (Pseudotsuga menziesii (Mirb.) FRANCO) se caractérise avant tout par un très grand potentiel de productivité ... [more ▼]

Considéré par beaucoup de sylviculteurs européens comme une essence d'avenir, le douglas (Pseudotsuga menziesii (Mirb.) FRANCO) se caractérise avant tout par un très grand potentiel de productivité assorti de propriétés mécaniques remarquables ( de CHAMPS et DEMACQ, 1996). Encore faut-il que le sylviculteur identifie clairement l'itinéraire sylvicole à assigner à ces peuplements sur des bases aussi objectives que possibles. Les critères devant orienter ce choix relèvent autant de l'adéquation essence-station qui est un préalable à leur installation, que des exigences du marché ou encore, dans le contexte d'une sylviculture de production, de la rentabilité financière du projet sylvicole retenu. L'objectif de la présente étude est d'évaluer de manière générale la rentabilité financière potentielle d'une plantation de douglas en Wallonie. Au travers d'une comparaison de quelques scénarios sylvicoles représentatifs des grandes tendances en matière de culture de cette essence, nous essaierons également d'apprécier l'impact du choix sylvicole, non seulement sur la rentabilité du projet, mais également sur les caractéristiques dendrométriques, voire technologiques, des peuplements ainsi façonnés. Une telle démarche de comparaison de scénarios sylvicoles implique avant tout de disposer d'un outil capable de prédire, d'une manière aussi fiable que possible, l'évolution sur plusieurs décennies de peuplements forestiers soumis à un traitement sylvicole donné. Il convient également de bien préciser la démarche retenue pour effectuer les comparaisons de rentabilité financière en insistant sur l'interprétation à donner à celles-ci. Nous présenterons tout d'abord le modèle de croissance que nous avons utilisé dans le cadre de cette étude (paragraphe 2) et préciserons les modalités d'évaluation financière mises en oeuvre (paragraphe 3). Nous détaillerons ensuite, sur base des principaux paramètres sylvicoles (révolution, densité de plantation, calendrier et nature des éclaircies), les différents scénarios considérés dans cette comparaison (paragraphe 4), ainsi que leurs performances respectives (paragraphe 5). Nous conclurons enfin sur la portée des résultats enregistrés et les limitations d'une telle étude (paragraphe 6). [less ▲]

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See detailOral contraception and cardiovascular risk factors during adolescence
Paulus, Dominique; Saint-Remy, Annie ULg; JeanJean, Michel

in Contraception (2000)

The objective of the present study was to analyze the pattern of oral contraceptive (OC) use in teenagers and to examine the relationship between OC use and other cardiovascular risk factors. The study ... [more ▼]

The objective of the present study was to analyze the pattern of oral contraceptive (OC) use in teenagers and to examine the relationship between OC use and other cardiovascular risk factors. The study was conducted in 24 Belgian secondary schools. Most students (1526 adolecents aged 12-17 years) agreed to participate (participation rate: 83.6%). Smoking, physical activity habits, menarche, and OC use were assessed by a self-administered questionnaire. Total cholesterol level, blood pressure and anthropometric measurements were also measured. Fourteen per cent of mature girls (14%, n=92) were OC users. Two-thirds of them (66.3%, n=61) were taking OC which contained either gestodene or desogestrel. Blood pressure and BMI were similar for OC users and non-users. Total cholesterol level was significantly higher in OC users than in non-users (191 mg/dL versus 172 mg/dL). Logistic regression model confirmed the significant influence of OC use on total cholesterol level (OR=3.08). OC users were also often smokers (39% versus 20% for non-users). In conclusion, the present study has found significant relationship between OC use and cardiovascular risk factors i.e., high total cholesterol and smoking. The first implication is a need for further research on lipoprotein profile in young OC users. Secondly, the combined use of OC and smoking in teenagers calls for preventive actions. [less ▲]

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See detailEpidemiologische bewaking van boviene spongiforme encefalopathie in Belgïe: Jaaroverzicht voor 1998
Saegerman, Claude ULg; Dechamps, P.; Vanopdenbosch, E. et al

in Vlaams Diergeneeskundig Tijdschrift (2000), 69

In 1998 werden 6 runderen tussen de 54 en 71 maanden ouderdom, afkomstig van de provincies West-Vlaanderen (3 gevallen), Oost-Vlaanderen (2 gevallen) en Luik (1 geval), gediagnostiseerd als gevallen van ... [more ▼]

In 1998 werden 6 runderen tussen de 54 en 71 maanden ouderdom, afkomstig van de provincies West-Vlaanderen (3 gevallen), Oost-Vlaanderen (2 gevallen) en Luik (1 geval), gediagnostiseerd als gevallen van boviene spongiforme encephalopathie (BSE). De hypotheses betreffende de oorsprong van de infectie op zijn de volgende : het optreden van sporadische gevallen zonder duidelijk definieerbare oorzaak; de mogelijke kruiscontaminatie tussen voeder voor monogastrische dieren met daarin dierlijk meel en voeder voor herkauwers waarin geen dierlijk meel is verwerkt en dit tijdens het fabricatieproces, de stockage, het transport of de distributie; het gebruik van dierlijk beendermeel in het voeder voor runderen geproduceerd voor de ban (van kracht vanaf 27/7/1994). Algemeen kan men dus stellen dat in België de aanwezigheid van gecontamineerd diermeel als risicofactor voor BSE niet kan worden uitgesloten. De oorsprong van deze diermelen kon nog niet gedetermineerd worden. [less ▲]

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See detailLa commission d'hemovigilance du CHU.
Baudoux, Etienne ULg; Blaffart, Francine ULg; Bouffioux, Christian ULg et al

in Revue Médicale de Liège (2000), 55(9), 878-80

As suggested by the National Blood Council, a Hemovigilance Committee was set up in the University Hospital of Liege in 1995. A multidisciplinary discussion takes place on any action aiming at the ... [more ▼]

As suggested by the National Blood Council, a Hemovigilance Committee was set up in the University Hospital of Liege in 1995. A multidisciplinary discussion takes place on any action aiming at the improvement of transfusion safety, and the follow-up of its implementation. The first issue to be discussed was the set up of a detailed documentation of all blood transfusions. The data are now recorded on a single document allowing proper identification of people and products involved, and of the eventual incidents. This document has lead to a better transfusion safety and to an improved administrative management of blood transfusion. The Commission has been coordinating two multi-centric studies analyzing the consumption of fresh blood products and the incidence of transfusion reactions. Among blood-saving policies, autologous transfusion and volume reduction of samples drawn for laboratory purposes have been discussed. Other measures were taken to improve the labeling of samples for cross-mach and to actively follow-up transfusion reactions. By its actions and advises, the Commission aims to direct strategies towards a safe and rational use of blood products. [less ▲]

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See detailThe afa-related gene cluster in necrotoxigenic and other Escherichia coli from animals belongs to the afa-8 variant
Gérardin, J.; Lalioui, L.; Jacquemin, E. et al

in Veterinary Microbiology (2000), 76

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See detailDelayed control of axial compressors
Aernouts, Werner; Sepulchre, Rodolphe ULg; Roose, Dirk

in International Journal of Bifurcation & Chaos in Applied Sciences & Engineering (2000), 10(5),

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See detailAffections musculaires et intolérance à l'effort. 2- Traitement
Art, Tatiana ULg; Amory, Hélène ULg; Lekeux, Pierre ULg

in Pratique Vétérinaire Equine (2000), 32

The muscular condition, rhabdomyolysis, may cause exercise intole¬rance in the sporting horse. When the condition is recurring, it is often difficult for the equine practitioner to establish the clinical ... [more ▼]

The muscular condition, rhabdomyolysis, may cause exercise intole¬rance in the sporting horse. When the condition is recurring, it is often difficult for the equine practitioner to establish the clinical diagnosis (is the horse suffering from rhabdomyolysis or not ?) and the aetiology (what is/are the cause(s) of the condition ?) and also to provide an effective treatment [less ▲]

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See detailHigh Resolution Electron Energy Loss Spectroscopy Investigation of the Vibrational Structure and Order of an Octadecanethiol Monolayer on Gold Substrates
Duwez, Anne-Sophie ULg; Yu, Li-Ming; Riga, Joseph et al

in Journal of Physical Chemistry B (2000), 104

The vibrational spectra induced by electron beam from octadecanethiol monolayers adsorbed on gold are reported as a contribution to study in detail the structure of the layers, through an analysis of the ... [more ▼]

The vibrational spectra induced by electron beam from octadecanethiol monolayers adsorbed on gold are reported as a contribution to study in detail the structure of the layers, through an analysis of the interaction mechanisms between the electrons and these organic ultrathin films. To show the different spatial distribution of scattered electrons from dipole and impact interactions with the monolayer, angular distributions of elastic and inelastic scattered electrons were measured for various primary energies. The absolute electron scattering loss probabilities from both dipole and impact interactions were estimated for different vibrational modes. The study of these different mechanisms was first hampered by the poor order of the layers adsorbed on evaporated gold. It became therefore highly desirable to perform the experiments on a single-crystal substrate. Using Au(111) and Au(100) single crystals as substrates, it was possible to separate the spectral response from impact and dipole interacting electrons. A negative ion resonant behavior has been observed in the energy dependence of the electron scattering differential cross sections [less ▲]

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See detailErgotamine in the acute treatment of migraine: a review and European consensus.
Tfelt-Hansen, P.; Saxena, P. R.; Dahlof, C. et al

in Brain : A Journal of Neurology (2000), 123 ( Pt 1)

Ergotamine has been used in clinical practice for the acute treatment of migraine for over 50 years, but there has been little agreement on its place in clinical practice. An expert group from Europe ... [more ▼]

Ergotamine has been used in clinical practice for the acute treatment of migraine for over 50 years, but there has been little agreement on its place in clinical practice. An expert group from Europe reviewed the pre-clinical and clinical data on ergotamine as it relates to the treatment of migraine. From this review, specific suggestions for the patient groups and appropriate use of ergotamine have been agreed. In essence, ergotamine, from a medical perspective, is the drug of choice in a limited number of migraine sufferers who have infrequent or long duration headaches and are likely to comply with dosing restrictions. For most migraine sufferers requiring a specific anti-migraine treatment, a triptan is generally a better option from both an efficacy and side-effect perspective. [less ▲]

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See detailLe champ des études migratoires et ethniques en Belgique
Martiniello, Marco ULg

in La Revue Générale (2000), 135(10), 19-28

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See detailGestire la diversità culturale e identitaria
Martiniello, Marco ULg

in Il Mulino (2000), anno XLIX(391), 881-889

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See detailAn Appraisal of 18-Fluorodeoxyglucose Positron Emission Tomography for Melanoma Staging
Paquet, Philippe ULg; Henry, Frédérique ULg; Belhocine, Tarik et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (2000), 200(2), 167-9

BACKGROUND: Positron emission tomography (PET scan) using fluorodeoxyglucose (FDG) is increasingly recognized as a reliable diagnostic method to detect metastases of malignant melanoma (MM). OBJECTIVE: To ... [more ▼]

BACKGROUND: Positron emission tomography (PET scan) using fluorodeoxyglucose (FDG) is increasingly recognized as a reliable diagnostic method to detect metastases of malignant melanoma (MM). OBJECTIVE: To compare the diagnostic performance of 18-FDG PET scan to that of conventional imaging. METHODS: A total of 28 assessments were conducted in 24 patients at risk of metastatic MM. Results: The diagnostic accuracy was over 80% and similar for PET scan and conventional imaging. CONCLUSION: Both the specificity and sensitivity of PET scan are high although not perfect. Confrontation of data with anatomical location and clinicopathological findings remains mandatory. [less ▲]

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See detailNovel functionalization routes of poly(ε-caprolactone)
Lecomte, Philippe ULg; Detrembleur, Christophe ULg; Lou, Xudong et al

in Macromolecular Symposia (2000), 157

The aluminum alkoxide mediated ring opening polymerization of functional lactones, such as γ-ethylene ketal-ε-caprolactone (TOSUO), γ-(triethylsilyloxy)-ε-caprolactone (SCL) and γ-bromo-ε-caprolactone ... [more ▼]

The aluminum alkoxide mediated ring opening polymerization of functional lactones, such as γ-ethylene ketal-ε-caprolactone (TOSUO), γ-(triethylsilyloxy)-ε-caprolactone (SCL) and γ-bromo-ε-caprolactone (γBrCL), is a versatile route to polyesters containing ketal, ketone, alcohol and bromide groups. As result of living polyaddition mechanism, random and block copolymerization of εCL and γBrCL has been successfully carried out. The reactivity ratios are quite similar (1.08 for ε-CL, and 1.12 for γBrCL). These random copolymers are semicrystalline when they contain less than 30 mol% of γBrCL, otherwise they are amorphous. No transesterification reaction occurs during the sequential polymerization of ε-CL and γBrCL leading to block copolymers. Reaction of poly(εCL-co-γBrCL) with pyridine provides quantitatively a polycationic polyester. Furthermore, the reaction of this random copolymer with l,8-diazabicyclo[5.4.0] undec-7-ene (DBU) is a route to unsaturated polyesters, whose the non conjugated double bonds can be quantitatively converted into epoxides by reaction with m-chloroperbenzoic acid (mCPBA). No chain degradation is detected during these derivatization reactions of poly (εCL-co-γBrCL). [less ▲]

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See detailLes brulis, un outil de gestion de la faune en region Afrique inter-tropicale.
Cornelis, D.; Lungren, C.; Ouedraogo, Mohamar moussa ULg et al

in Parcs & Réserves (2000), 55(3-4),

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See detailAnalysis of foodborne disease in Belgium in 1997.
Van Loock, F.; Ducoffre, G.; Dumont, J.-M. et al

in Acta Clinica Belgica (2000), 55

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See detailEvidence-based medicine. Apport des etudes epidemiologiques.
REGINSTER, Jean-Yves ULg; BETZ, Romain ULg

in Revue Médicale de Liège (2000), 55(4), 211-5

Epidemiological studies, more specifically those related to analytical epidemiology are a major determinant of evidence-based medicine. When classifying the value of the different epidemiological studies ... [more ▼]

Epidemiological studies, more specifically those related to analytical epidemiology are a major determinant of evidence-based medicine. When classifying the value of the different epidemiological studies, based on their level of causality, cohort studies are ranked higher than case-control studies, mainly due to the fact that they allow direct collection of information on exposition to risk factors and health consequences. However, case-control studies can also provide an important information, if a specific effort is dedicated to the analyses of the circumstances of the exposition. Meta-analysis increases, by pooling them, the statistical power of individual studies of limited size. Meta-analysis can also be considered as an important source of evidence in the perspective of evidence-based medicine. [less ▲]

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See detailOnze ans de responsabilité médicale pénale sur le ressort de la Cour d'appel de Liège du 01.01.1985 au 31.12.1995
Boxho, Philippe ULg

in Journal de Médecine Légale, Droit Médical (2000), 78/43

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See detailThe photoabsorption and Constant Ion State Spectroscopy of Vinyl Bromide.
Hoxha, A.; Locht, Robert ULg; Leyh, Bernard ULg et al

in Chemical Physics (2000), 260

In this paper we report the photoabsorption and the constant ion state spectroscopy of vinyl bromide (C2H3Br). The photoabsorption spectrum was measured using synchrotron radiation and was investigated in ... [more ▼]

In this paper we report the photoabsorption and the constant ion state spectroscopy of vinyl bromide (C2H3Br). The photoabsorption spectrum was measured using synchrotron radiation and was investigated in detail between 5.0 and 12.0 eV photon energy revealing many previously unobserved structures. These features were analyzed in terms of valence to virtual valence transitions and Rydberg series. The examination of the three Rydberg series converging towards the first ionization threshold (2a"->ns, 2a"->np and 2a"->nd) leads to wavenumbers of 335+/-30, 690+/-30 and 1305+/-30 cm-1. The vibrational wavenumbers of the progressions belonging to Rydberg series converging towards the second ionization threshold are 485+/-30 and 1145+/-50 cm-1. Ab initio calculations helped the assignment of the valence transitions and of the observed vibrational wave numbers in the Rydberg series. Constant Ionic State spectra were recorded for vibronic states corresponding to the first and the second electronic states of the ion. Their fine structures are assigned to the autoionization of Rydberg states. The autoionization decay of these Rydberg states is analyzed qualitatively in terms of the vibrational nature of the final ionic state. [less ▲]

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See detailVolume tables for small trees of larch (Larix sp.) in the southern part of Belgium
Rondeux, Jacques ULg; Pauwels, D.

in Forestry (2000), 73(1), 91-93

Volume tables have been constructed for European larch (Larix decidua Mill.), Japanese larch (Larix kaempferi (Lamb.) Carr.) and hybrid larch (Larix X eurolepis Henry) trees in the Ardenne (southern part ... [more ▼]

Volume tables have been constructed for European larch (Larix decidua Mill.), Japanese larch (Larix kaempferi (Lamb.) Carr.) and hybrid larch (Larix X eurolepis Henry) trees in the Ardenne (southern part of Belgium), which is a natural region located at elevations ranging from 340 to 550 m on mainly siliceous rocks. The application of the proposed tables is only for trees whose diameters (d.b.h.) are less than 22 cm over bark at 1.3 m above ground level. They are particularly useful for estimating total tree volume of trees (excluding branches) of early thinnings and volume increment of small-sized trees in genetic improvement experiments. The volume equations are based on data collected over a wide range of site conditions. In these regional volume tables, the volumes (total volume of the stem and volume to an upper diameter limit of 7 cm) are correlated with both d.b.h. and total height. [less ▲]

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See detailGeneral report - Session on connections
Jaspart, Jean-Pierre ULg

in Journal of Constructional Steel Research (2000), 55

As a result of a world-wide intensive research activity, a new design concept for structural moment resistant joints has been suggested and implemented in design codes. In the present paper, its ... [more ▼]

As a result of a world-wide intensive research activity, a new design concept for structural moment resistant joints has been suggested and implemented in design codes. In the present paper, its background is first briefly described and the main contributions to its development are presented. As a matter of fact, because of the high number of past and ongoing researches, reports and papers devoted to this topic, an exhaustive list of all these works could not be established in a limited number of pages. The possibilities of extension of the new design concepts, which have been first developed for steel beam-to-column joints under static loading, are particularly pointed out. This aspect appears quite important as in the near future it should provide designers with a unified design approach for structural joints whatever their loading, their configurations and the nature of their constitutive material(s). [less ▲]

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See detailThe Optimisation Of The Helix/Helix Interaction Of A Transmembrane Dimer Is Improved By The Impala Restraint Field
Ducarme, P.; Thomas, Annick ULg; Brasseur, Robert ULg

in Biochimica et Biophysica Acta-Biomembranes (2000), 1509(1-2), 148-54

A continuous membrane model (IMPALA) was previously developed to predict how hydrophobic spans of proteins insert in membranes (Mol. Mod. 2 (1996) 27). Using that membrane model, we looked for the ... [more ▼]

A continuous membrane model (IMPALA) was previously developed to predict how hydrophobic spans of proteins insert in membranes (Mol. Mod. 2 (1996) 27). Using that membrane model, we looked for the interactions between several hydrophobic spans. We used the glycophorin A dimer as an archetype of polytopic protein to validate the approach. We find that the native complex do not dislocate when it is submitted to a 10(5) steps optimisation whereas separated spans converge back to a native-like complex in the same conditions. We also observe that IMPALA restraints are not strictly mandatory but do increase the efficiency of the procedure. [less ▲]

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See detailRespiratory adaptation to extra uterine life in healthy newborn calves
Uysterpruyst, C. H.; Reinhold, P.; Coghe, J. et al

in European Respiratory Journal (2000), 16(suppl 31), 300

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