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See detailQuantitative short-term study of Anal sphincter function after chemoradiation for rectal cancer
Gervaz, Pascal; Rotholtz, Nicolas; Pisano, Michele et al

in Langenbeck's Archives of Surgery (2001), 136

Hypothesis: Pelvic irradiation adversely affects anal sphincter function after proctectomy with coloanal anastomosis for low rectal and middle rectal (,10 cm from the anal verge) tumors. Design: Case ... [more ▼]

Hypothesis: Pelvic irradiation adversely affects anal sphincter function after proctectomy with coloanal anastomosis for low rectal and middle rectal (,10 cm from the anal verge) tumors. Design: Case-control study. Setting: Private, tertiary care referral center. Patients: Patients treated for low rectal adenocarcinoma between January 1, 1994, and October 31, 1999. Interventions: Anal manometric data were prospectively collected at the time of initial diagnosis and before ileostomy closure. Main Outcome Measures: Mean and maximum resting pressures (RPs) and squeeze pressures, threshold volume for sensation, and maximal tolerable volume. Results: Twenty-three patients in the surgery group and 19 in the chemoradiotherapy group were considered for [less ▲]

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See detailLa recombinaison chez les alphaherpèsvirus
Meurens, François; Schynts, Frédéric; Thiry, Etienne ULg

in Annales de Médecine Vétérinaire (2001), 145

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See detailÉvolution des accessibilités et des mobilités des localisations commerciales
Merenne-Schoumaker, Bernadette ULg

in Travaux de l’Institut de Géographie de Reims (2001), 27(107-108), 7-23

In order to be able to study the links between the evolution of accessibilities and mobilities and the dynamics of the commercial localizations, the article has been organized in three parts : firstly ... [more ▼]

In order to be able to study the links between the evolution of accessibilities and mobilities and the dynamics of the commercial localizations, the article has been organized in three parts : firstly, the definition of the concepts of accessibility and mobility as well as the distance; secondly, analysis of the role of these two concepts in the commercial field and the their most evident recent evolutions; lastly, research into corresponding links. On the basis of this work, everything indicates the priority of mobility over accessibility as well as very close relations between the mutations of urbanized territories and the installation of the new commercial framework, which is strongly governed by car mobility. [less ▲]

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See detailA note on the use of fluorescently labelled algae for the determination of gut passage time in Bosmina and Daphnia
Cauchie, Henry-Michel ULg; Deguée, N.; Joaquim-Justo, Célia ULg et al

in Verhandlungen der Internationalen Vereinigung für Theoretische und Angewandte Limnologie = Proceedings of the International Association of Theoretical and Applied Limnology (2001), 27

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See detailMicrowave Corneosurfametry and the Short-Duration Dansyl Chloride Extraction Test for Rating Concentrated Irritant Surfactants
Goffin, Véronique ULg; Pierard, Gérald ULg

in Dermatology : International Journal for Clinical & Investigative Dermatology (2001), 202(1), 46-8

BACKGROUND: There are ethical concerns to conduct in vivo tests in the animal and human to provide evidence that cosmetics and other topical products are safe. OBJECTIVE: To compare two methods, namely ... [more ▼]

BACKGROUND: There are ethical concerns to conduct in vivo tests in the animal and human to provide evidence that cosmetics and other topical products are safe. OBJECTIVE: To compare two methods, namely the short-duration dansyl chloride extraction test and the microwave corneosurfametry bioassay, to test the irritation potential of concentrated surfactant systems. METHODS: Five surfactants and water were tested using the in vivo test and the bioassay. RESULTS: A significant linear correlation was found between data yielded by the two procedures. CONCLUSION: The short-duration dansyl chloride extraction test and the microwave corneosurfametry bioassay provide similar information. The latter has the advantage of being safe. [less ▲]

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See detailCaractérisation et valorisation du savoir paysan sur les insectes nuisibles du pois cajan (Cajanus cajan (L.) Millsp.) dans le Nord de l'Ouganda
Velay, F.; Baudoin, Jean-Pierre ULg; Mergeai, Guy ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2001), 5(2), 105-114

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See detailProgramme international pour le suivi des acquis des élèves (PISA) de l'OCDE
Lafontaine, Dominique ULg; Baye, Ariane ULg; Matoul, Anne ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), 7-8(7-8), 53-57

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See detailQuelques réflexions à propos de l'incidence des fixations, remises ou redistributions de la cause sur la qualification d'un jugement ou d'un arrêt
Boularbah, Hakim ULg

in Revue de Droit Judiciaire et de la Preuve = Tijdschrift voor Procesrecht en Bewijsrecht (2001)

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See detailMonitoring biologique des greffes de cellules souches hématopoïétiques
GOTHOT, André ULg

in Focus Diagnostica (2001), 9

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See detailRole of β-Oxidation Enzymes in γ-Decalactone Production by the Yeast Yarrowia lipolytica
Waché, Y.; Aguedo, Mario ULg; Choquet, A. et al

in Applied and Environmental Microbiology (2001), 67(12), 5700-5704

Some microorganisms can transform methyl ricinoleate into γ-decalactone, a valuable aroma compound, but yields of the bioconversion are low due to (i) incomplete conversion of ricinoleate (C18) to the C10 ... [more ▼]

Some microorganisms can transform methyl ricinoleate into γ-decalactone, a valuable aroma compound, but yields of the bioconversion are low due to (i) incomplete conversion of ricinoleate (C18) to the C10 precursor of γ-decalactone, (ii) accumulation of other lactones (3-hydroxy-γ-decalactone and 2- and 3-decen-4-olide), and (iii) γ-decalactone reconsumption. We evaluated acyl coenzyme A (acyl-CoA) oxidase activity (encoded by the POX1 through POX5 genes) in Yarrowia lipolytica in lactone accumulation and γ-decalactone reconsumption in POX mutants. Mutants with no acyl-CoA oxidase activity could not reconsume γ-decalactone, and mutants with a disruption of pox3, which encodes the short-chain acyl-CoA oxidase, reconsumed it more slowly. 3-Hydroxy-γ-decalactone accumulation during transformation of methyl ricinoleate suggests that, in wild-type strains, β-oxidation is controlled by 3-hydroxyacyl-CoA dehydrogenase. In mutants with low acyl-CoA oxidase activity, however, the acyl-CoA oxidase controls the β-oxidation flux. We also identified mutant strains that produced 26 times more γ-decalactone than the wild-type parents. [less ▲]

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See detailMerisier : les variétés multiclonales ont-elles un avenir ?
Curnel, Yanick; van de waele, Isabelle; Jacques, Dominique et al

in Silva Belgica (2001), 108(2), 32-37

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See detailThe effect of risedronate on hip fracture risk in elderly women with osteoporosis
Bensen, W; Eastell, R; Reginster, Jean-Yves ULg et al

in Journal of Rheumatology (2001), 28(S63), 24

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See detailPrésentation
Badir, Sémir ULg; Arrivé, Michel

in Linx (2001), 44

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See detailLes mélèzes
Rondeux, Jacques ULg; Pauwels, D.

in Fiche technique (2001)

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See detailEntre symbolisme et avant-garde : le modernisme de Franz Hellens dans la première série du Disque Vert (1921-1925)
Denis, Benoît ULg

in Textyles : Revue des Lettres Belges de Langue Française (2001), (20), 66-75

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See detailStrontium ranelate increases cartilage matrix formation.
Henrotin, Yves ULg; Labasse, Alain; Zheng, S. X. et al

in Journal of Bone and Mineral Research (2001), 16(2), 299-308

Based on previous studies showing that strontium ranelate (S12911) modulates bone loss in osteoporosis, it could be hypothesized that this drug also is effective on cartilage degradation in osteoarthritis ... [more ▼]

Based on previous studies showing that strontium ranelate (S12911) modulates bone loss in osteoporosis, it could be hypothesized that this drug also is effective on cartilage degradation in osteoarthritis (OA). This was investigated in vitro on normal and OA human chondrocytes treated or not treated with interleukin-1beta (IL-1beta). This model mimics, in vitro, the imbalance between chondroformation and chondroresorption processes observed in vivo in OA cartilage. Chondrocytes were isolated from cartilage by enzymatic digestion and cultured for 24-72 h with 10(-4)-10(-3) M strontium ranelate, 10(-3) M calcium ranelate, or 2 x 10(-3) M SrCl2 with or without IL-1beta or insulin-like growth factor I (IGF-I). Stromelysin activity and stromelysin quantitation were assayed by spectrofluorometry and enzyme amplified sensitivity immunoassay (EASIA), respectively. Proteoglycans (PG) were quantified using a radioimmunoassay. Newly synthesized glycosaminoglycans (GAGs) were quantified by labeled sulfate (Na2(35)SO4) incorporation. This method allowed the PG size after exclusion chromatography to be determined. Strontium ranelate, calcium ranelate, and SrCl2 did not modify stromelysin synthesis even in the presence of IL-1beta. Calcium ranelate induced stromelysin activation whereas strontium compounds were ineffective. Strontium ranelate and SrCl2 both strongly stimulated PG production suggesting an ionic effect of strontium independent of the organic moiety. Moreover, 10(-3) M strontium ranelate increased the stimulatory effect of IGF-I (10(-9) M) on PG synthesis but did not reverse the inhibitory effect of IL-1beta. Strontium ranelate strongly stimulates human cartilage matrix formation in vitro by a direct ionic effect without stimulating the chondroresorption processes. This finding provides a preclinical basis for in vivo testing of strontium ranelate in OA. [less ▲]

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See detailDes gribouillis aux premières lettres : le développement précoce de l’écrit.
Maillart, Christelle ULg; Schelstrate, Marie-Anne

in Langage et l'Homme (Le) : Recherches Pluridisciplinaires sur le Langage (2001), 34(2), 103-120

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See detailQuelques outils numériques de gestion des eaux de surface
Pirotton, Michel ULg; Lejeune, André ULg; Archambeau, Pierre ULg et al

in Bulletin de l'A.I.Lg (2001), (2), 29-31

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See detailThe 'Aesthetics of Personalism' in Caryl Phillips's Writing: Complexity as a New Brand of Humanism
Ledent, Bénédicte ULg

in World Literature Written in English (2001), 39(1), 75-85

This paper attempts to underline the epistemological implications of Phillips's handling of diasporic history through a focus on individual lives in Cambridge (1991) and The Nature of Blood (1997). His ... [more ▼]

This paper attempts to underline the epistemological implications of Phillips's handling of diasporic history through a focus on individual lives in Cambridge (1991) and The Nature of Blood (1997). His confessional first-person narratives highlight the intricacies inherent in human nature, thereby resisting the globalizing discourse of liberal humanism. Even more importantly, his fictions seem to illustrate a new, more understanding approach to this often hackneyed term, for they give voice to individuals whose multiple differences are, paradoxically, part proof of a common humanity, viewed here as an inclusive rather than exclusive concept. [less ▲]

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See detailMigraine
Sandor, Peter S.; Agosti, Reto; Schoenen, Jean ULg

in Pain Clinical Updates (2001), 9

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See detailLes bioindustries fertilisent la valorisation
Thonart, Philippe ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2001), 5(3), 131-134

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See detailThe dispositional inference strikes back: Situational focus and dispositional suppression in causal attribution
Yzerbyt, V. Y.; Corneille, O.; Dumont, Muriel ULg et al

in Journal of Personality & Social Psychology (2001), 81(3), 365-376

The authors propose that correction of dispositional inferences involves the examination of situational constraints and the suppression of dispositional inferences. They hypothesized that suppression ... [more ▼]

The authors propose that correction of dispositional inferences involves the examination of situational constraints and the suppression of dispositional inferences. They hypothesized that suppression would result in dispositional rebound. In Study 1, participants saw a video of either a free or a forced speaker. Participants shown a forced speaker later made stronger dispositional inferences about a 2nd, free speaker than control participants did. Study 2 provided evidence for higher rebound among participants who reported trying harder to suppress dispositional inferences during the Ist video. In Study 3, participants were asked to focus on situational constraints or to avoid thinking about the speaker's characteristics. Only the latter instructions led to a dispositional rebound. These data support the view that the correction of dispositional inferences involves 2 processes that lead to distinct consequences in subsequent attribution work. [less ▲]

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See detailRichesse du patrimoine campanaire liégeois : un carillon de Nicolas Chapelle pour la Collégiale Sainte-Croix en 1621
Marganne, Marie-Hélène ULg; Mélard, Marc; Félix, Jean-Pierre

in Bulletin de la Société Royale Le Vieux-Liège (2001), 294

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See detailRole of interface deformations in Benard-Marangoni instability
Lebon, Georgy ULg; Dauby, Pierre ULg; Regnier, Vincent

in Acta Astronautica (2001), 48(5-12), 617-627

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See detailComparison of basic density and longitudinal shrinkage in tension wood and opposite wood in young stems of Poplar (P. euramericana cv “ Ghoy ”) when subjected to a gravitational stimulus
Jourez, Benoît ULg; Riboux, Alain; Leclercq, André

in Canadian Journal of Forest Research = Journal Canadien de la Recherche Forestière (2001), 31(10), 1676-1683

In a green house, under controlled conditions, young shoots, taken from poplar cuttings (P. euramericana cv “ Ghoy ”), were artificially inclined in order to quantify the modifications of physical ... [more ▼]

In a green house, under controlled conditions, young shoots, taken from poplar cuttings (P. euramericana cv “ Ghoy ”), were artificially inclined in order to quantify the modifications of physical properties induced by a gravitational stimulus. At the end of the growing season, basic density and longitudinal shrinkage were measured on very small samples taken from pure tension wood tissue observed on the upper face of the inclined axis and compared with opposite wood tissue, free of gelatinous fibers, developed on the opposite lower face. In a second step, shoots bend at two different lean intensities were analyzed. On young poplar wood, gravitational stimulus was found to have a significant effect on physical properties. Relations between basic density and longitudinal shrinkage are different depending on the types of wood considered. Shrinkage appears more sensitive to lean intensity in the range considered here [less ▲]

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See detailSubclinical cerebellar impairment in the common types of migraine: a three-dimensional analysis of reaching movements.
Sandor, P. S.; Mascia, A.; Seidel, L. et al

in Annals of Neurology (2001), 49(5), 668-72

Mutations in the CACNA1A gene can cause familial hemiplegic migraine (FHM) and/or cerebellar ataxia CACNA1A codes for the alpha1 subunit of P/Q-Ca2+ channels and is highly expressed in the cerebellum ... [more ▼]

Mutations in the CACNA1A gene can cause familial hemiplegic migraine (FHM) and/or cerebellar ataxia CACNA1A codes for the alpha1 subunit of P/Q-Ca2+ channels and is highly expressed in the cerebellum. Using a pointing paradigm and infrared optoelectronic tracking system, we found subclinical hypermetria and other subtle cerebellar signs in the common forms of migraine. These were more pronounced in migraine with than without aura. Whether this reflects involvement of Ca2+ channel genes in the common types of migraine needs to be investigated by genetic analyses. [less ▲]

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See detailHorace, lecteur du livre V de Lucrèce (Satires, I, 3, 99-112)
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (2001), 60(1), 16-20

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See detailAn overlay tree building control protocol
Mathy, Laurent ULg; Canonico, R.; Hutchison, D.

in Networked Group Communication (2001)

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See detailVers un système d'information régional à caractère territorial
Rondeux, Jacques ULg

in Cahiers de l'Urbanisme (Les) (2001), (34), 73-79

Il n'est pas imaginable de penser, d'agir et de décider en matière de développement du territoire wallon, sans disposer d'informations de qualité sur les différentes facettes de l'occupation de l'espace ... [more ▼]

Il n'est pas imaginable de penser, d'agir et de décider en matière de développement du territoire wallon, sans disposer d'informations de qualité sur les différentes facettes de l'occupation de l'espace et nombre d'activités très diversifiées qui en découlent ou l'influencent. Créer une structure fonctionnelle interactive organisant la cohérence des données pertinentes, disponibles ou à récolter, évaluer leur validité, assurer et contrôler leur diffusion, en un mot gérer celles-ci pour mieux les valoriser justifie la création d'un outil mobilisateur d'aide à la décision dont les principaux objectifs, les concepts, l'organisation et les perspectives sont décrits dans les lignes qui suivent. [less ▲]

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See detailAutour d'Henri Bles à Liège
Allart, Dominique ULg; Fraiture Pascale; Oger, Cécile ULg et al

in Feuillets de la Cathédrale de Liège (2001), 46-53

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See detailThe Vacuum UV Photoabsorption Spectrum of Methyl Chloride (CH3Cl) and its perdeuterated Isotopomer CD3Cl. I. A Rydberg Series Analysis.
Locht, Robert ULg; Leyh, Bernard ULg; Hoxha, A. et al

in Chemical Physics (2001), 272

The vacuum UV photoabsorption spectrum of CH3Cl has been recorded between 6 and 25 eV. A large number of vibronic bands are observed. These were partly ascribed to vibrationless Rydberg transitions. In ... [more ▼]

The vacuum UV photoabsorption spectrum of CH3Cl has been recorded between 6 and 25 eV. A large number of vibronic bands are observed. These were partly ascribed to vibrationless Rydberg transitions. In the higher energy range of 12-25 eV very weak diffuse bands are mostly assigned to transitions from the 3a1, 1e and 2a1 to 3s orbitals. In the 6-12 eV photon energy range, numerous weak to strong bands are observed. The sharpness of the features is very variable over the entire spectral region. In a first step, the interpretation of the spectrum and the assignment of the Rydberg transitions is based on the simple Rydberg formula. The observed features are classified in two groups of four series, each converging to one of the two spin-orbit components of the X2E state of CH3Cl+. Rydberg series of nsa1 (delta=1.069 and 1.064), npa1 (delta= 0.68 and 0.66), npe (delta= 0.438 and 0.427) and nd (delta= -0.040 and -0.092) characters are observed. The same measurements have been made for the first time on CD3Cl in the 6-12 eV photon energy range. The same Rydberg transitions are observed. Analogous series are characterized by about the same delta values: nsa1 (delta= 1.038 and 0.968), npa1 (delta= 0.65 and 0.61), npe (delta= 0.458 and 0.462) and nd (delta= -0.004 and -0.082). Ionization energies for CD3Cl X2E3/2 at 11.320 eV and X2E1/2 at 11.346 eV are deduced. In a second step, we fitted the experimental data for the nsa1 and npa1 states to an energy expression taking into account both the exchange interaction and the spin-orbit coupling. This accounts for the progressive switching from Hund's case (a) to Hund's case (c). [less ▲]

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See detailLe contrôle de la constitutionnalité des lois aux Pays-Bas
Kohl, Benoît ULg

in Chroniques de Droit Public = Publiekrechtelijke Kronieken (2001)

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See detailIpriflavone in the treatment of postmenopausal osteoporosis: a randomized controlled trial.
Alexandersen, P; Toussaint, André ULg; Christiansen, C et al

in JAMA : Journal of the American Medical Association (2001), 285(11), 1482-8

CONTEXT: Data on the efficacy and safety of ipriflavone for prevention of postmenopausal bone loss are conflicting. OBJECTIVES: To investigate the effect of oral ipriflavone on prevention of ... [more ▼]

CONTEXT: Data on the efficacy and safety of ipriflavone for prevention of postmenopausal bone loss are conflicting. OBJECTIVES: To investigate the effect of oral ipriflavone on prevention of postmenopausal bone loss and to assess the safety profile of long-term treatment with ipriflavone in postmenopausal osteoporotic women. DESIGN AND SETTING: Prospective, randomized, double-blind, placebo-controlled, 4-year study conducted in 4 centers in Belgium, Denmark, and Italy from August 1994 to July 1998. PARTICIPANTS: Four hundred seventy-four postmenopausal white women, aged 45 to 75 years, with bone mineral densities (BMDs) of less than 0.86 g/cm(2). INTERVENTIONS: Patients were randomly assigned to receive ipriflavone, 200 mg 3 times per day (n = 234), or placebo (n = 240); all received 500 mg/d of calcium. MAIN OUTCOME MEASURES: Efficacy measures included spine, hip, and forearm BMD and biochemical markers of bone resorption (urinary hydroxyproline corrected for creatinine and urinary CrossLaps [Osteometer Biotech, Herlev, Denmark] corrected for creatinine), assessed every 6 months. Laboratory safety measures and adverse events were recorded every 3 months. RESULTS: Based on intent-to-treat analysis, after 36 months of treatment, the annual percentage change from baseline in BMD of the lumbar spine for ipriflavone vs placebo (0.1% [95% confidence interval (CI), -7.9% to 8.1%] vs 0.8% [95% CI, -9.1% to 10.7%]; P =.14), or in any of the other sites measured, did not differ significantly between groups. The response in biochemical markers was also similar between groups (eg, for hydroxyproline corrected for creatinine, 20.13 mg/g [95% CI, 18.85-21.41 mg/g] vs 20.67 mg/g [95% CI, 19.41-21.92 mg/g]; P =.96); urinary CrossLaps corrected for creatinine, 268 mg/mol (95% CI, 249-288 mg/mol) vs 268 mg/mol (95% CI, 254-282 mg/mol); P =.81. The number of women with new vertebral fracture was identical or nearly so in the 2 groups at all time points. Lymphocyte concentrations decreased significantly (500/microL (0.5 x 10(9)/L]) in women treated with ipriflavone. Thirty-one women (13.2%) in the ipriflavone group developed subclinical lymphocytopenia, of whom 29 developed it during ipriflavone treatment. Of these, 15 (52%) of 29 had recovered spontaneously by 1 year and 22 (81%) of 29 by 2 years. CONCLUSIONS: Our data indicate that ipriflavone does not prevent bone loss or affect biochemical markers of bone metabolism. Additionally, ipriflavone induces lymphocytopenia in a significant number of women. [less ▲]

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See detailLa sémiologie selon L.J. Prieto
Badir, Sémir ULg

in Linx (2001), 44

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See detailThe short-range baryon baryon interaction in a chiral constituent quark model
Stancu, Floarea ULg; Glozman, Ya. L.

in Nuclear Physics A (2001), A683

The previous analysis of the short-range $NN$ repulsion originating from the Goldstone boson exchange hyperfine interaction between constituent quarks is revisited. We study in which respects the ... [more ▼]

The previous analysis of the short-range $NN$ repulsion originating from the Goldstone boson exchange hyperfine interaction between constituent quarks is revisited. We study in which respects the repulsion depends on the radial form of the spin-spin quark-quark force. We show that while the radial form affects the structure of the 6Q wave function, the short-range repulsion in the $NN$ system persists in any case. We extend our analysis to other $YN$ and $YY$ (flavor octet-octet) systems and demonstrate that the flavor-spin hyperfine interaction implies a short-range repulsion in these B=2 systems as well. [less ▲]

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See detailIntegrated modelling of the Belgian Coastal Zone
Delhez, Eric ULg; Carabin, G.

in Estuarine Coastal & Shelf Science (2001), 53(4), 477-491

The management of the water resources in coastal or delta plains asks for an integrated modelling of the water system at a regional scale. In the SALMON project, detailed descriptions of the groundwater ... [more ▼]

The management of the water resources in coastal or delta plains asks for an integrated modelling of the water system at a regional scale. In the SALMON project, detailed descriptions of the groundwater, river and marine domains are provided by coupling appropriate numerical models of these different sub-systems. The application of this three-fold model to the Scheldt and Belgian Coastal Zone reveals a marked river plume extending along the Belgian Coast with strong offshore gradients. This plume cannot be explained by the Eulerian residual transport velocity field but requires Lagrangian aspects to be taken into account. The computation of the age of this water mass shows that the different parts of the coastal zone are influenced by a discharge in the Grote Schijn River after a delay that varies between a few days (for the marine part of the estuary) to about 100 days (for the centre of the residual gyre). The computation shows also that the groundwater around Antwerp can also be contaminated by a pollution in the river but the resulting mass loss from the river does not lead to a significant reduction of the flux to the coastal zone. (C) 2001 Academic Press. [less ▲]

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See detailPurification and characterization of a 43.5 kDa keratinolytic metalloprotease from Microsporum canis.
Brouta, F.; Descamps, F.; Fett, Thomas ULg et al

in Medical Mycology (2001), 39(3), 269-275

A keratinolytic protease secreted by a feline clinical isolate of Microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by ... [more ▼]

A keratinolytic protease secreted by a feline clinical isolate of Microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by affinity chromatography on bacitracin-agarose and by hydrophobic chromatography on octyl-agarose. The enzyme had an apparent molecular mass of 43.5 kDa and the pI was 7.7. It had a significant activity against keratin azure, elastin-Congo red and denatured type I collagen (azocoll). Using the latter substrate, the optimum pH was around 8 and the apparent optimum temperature around 50 degrees C. The protease was strongly inhibited by 1,10-phenanthroline, phosphoramidon and EDTA. The first 13 N-terminal amino acid sequence showed a 61% homology with that of the extracellular metalloprotease of Aspergillus fumigatus and with the neutral protease I of A. oryzae, confirming that this 43.5 kDa keratinase is a metalloprotease. This keratinolytic metalloprotease could be a virulence-related factor involved in pathophysiological mechanisms of M. canis dermatophytosis. [less ▲]

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See detailL'activité physique de jeunes adolescents en Communauté française de Belgique
Piéron, Maurice; Cloes, Marc ULg

in Revue de l'Education Physique (2001), 41(1), 42-48

La santé figure dans la plupart des préoccupations des théoriciens et des praticiens de l'éducation physique. Les effets de santé associés à la pratique régulière d'activités physiques suscitent un ... [more ▼]

La santé figure dans la plupart des préoccupations des théoriciens et des praticiens de l'éducation physique. Les effets de santé associés à la pratique régulière d'activités physiques suscitent un intérêt fondamental chez de nombreux chercheurs. En effet, à deux reprises, un groupe de consensus s'est réuni pour établir un bilan des certitudes et des doutes en matière de relations entre l'activité physique et la santé. ... [less ▲]

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See detailOn the influence of aluminium content on the stability of retained austenite in multiphase TRIP-assisted steels
Mertens, Anne ULg; Jacques, Pascal J.; Lazarova, Roumiana et al

in Journal de Physique IV (2001), 11

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See detailIntroduction à la programmation avec Matlab sous windows
Akossou, A. Y. J.; Fonton, N. H.; Claustriaux, Jean-Jacques ULg

in Notes de Biométrie et d'Informatique (2001), 2

This note aims to introduce Matlab software. Through this presentation we show a few advantages of the software. This presentation is then illustrated by a few examples of program with the software.

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See detailIncinérateurs, crise dioxine et risques sanitaires pour la population belge
Bernard; Fierens; Mairesse et al

in Bulletin de la Classe des Sciences. Académie Royale de Belgique (2001), 1-6

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See detailAdaptive significance of facultative paedomorphosis in Triturus alpestris (Amphibia, Caudata): resource partitioning in an alpine lake
Denoël, Mathieu ULg; Joly, Pierre

in Freshwater Biology (2001), 46(10), 1387-1396

1. Facultative paedomorphosis is a polymorphism that has important evolutionary implications in promoting morphological differentiation and variation in habitat use. It occurs in several urodele species ... [more ▼]

1. Facultative paedomorphosis is a polymorphism that has important evolutionary implications in promoting morphological differentiation and variation in habitat use. It occurs in several urodele species throughout the world. Several hypotheses based on life-history theory have been proposed to explain the wide range of habitats in which facultative paedomorphosis occurs, suggesting multifactorial causes. 2. In harsh habitats, such as mountain lakes, paedomorphosis might promote niche partitioning between morphs. This hypothesis was tested by comparing micro-habitat use and diet of two coexisting morphs in an alpine lake. 3. Paedomorphs occupied all microhabitats in the lake while metamorphs occurred only along the shoreline or at the water surface. Paedomorphic newts were frequent in deep water, where they foraged mainly on plankton. Plankton was poorly exploited by metamorphic newts, which fed mainly on terrestrial insects. Difference between morphs in microhabitat use, and consequently in the diet, were consistent in both sexes and in juveniles. 4. In adults, the mass and energy value of stomach contents did not differ between morphs, suggesting a similar food availability in the habitats occupied. 5. This study indicates habitat partitioning between morphs involving dietary differences. Specific benefits and costs of each ontogenetic pathway may allow their coexistence in this deep and fishless lake. Paedomorphosis benefits individual newts by making new food resources available and presumably reducing competition at the shore of the lake. However, the proximate causes of such an ontogenetic switch remain unclear. [less ▲]

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See detailExperimental and theoretical investigations of the electrical properties of undoped and magnesium-doped GaN layers
Nguyen, Ngoc Duy ULg; Germain, Marianne; Schmeits, Marcel et al

in Journal of Crystal Growth (2001), 230

The ac characteristics of GaN : Mg and undoped GaN layers, grown by MOVPE on sapphire substrates, are measured for a wide range of temperature and bias conditions, in order to investigate the effect of ... [more ▼]

The ac characteristics of GaN : Mg and undoped GaN layers, grown by MOVPE on sapphire substrates, are measured for a wide range of temperature and bias conditions, in order to investigate the effect of the magnesium-related level on the transport properties. Two peaks, whose height and position depend on the measurement temperature, are observed in the admittance curves (G/ω versus frequency) of the Mg-doped samples, whereas only one peak appears in undoped samples. The study of the frequency dependence of the impedance, with a model including the two metallic Au/GaN junctions, the GaN layer itself, shows that, besides the effect of the differential resistance of the layer which plays a role in both sample types, the presence of a Mg-related deep level contributes to the observed variations of the peaks in the admittance curves of the p-doped samples. Results of a theoretical steady-state and small-signal analysis based on numerical modelling of the Au/GaN/Au heterostructure complete our analysis. [less ▲]

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See detailLes souches pathogènes d'Escherichia coli chez les chiens et les chats: III) Données bactériologiques et cliniques sur les souches nécrotoxinogènes et sur celles positives pour des adhésines
Mainil, Jacques ULg; Wilbaux, Myriam; Jacquemin, Etienne et al

in Annales de Médecine Vétérinaire (2001), 145(6), 343-354

The purpose of this study was to characterize 25 necrotoxigenic Escherichia coli type 1 (NTEC1), one necrotoxigenic E coli type 2 (NTEC2) and 16 non-necrotoxigenic E coli isolated, between 1979 and 1993 ... [more ▼]

The purpose of this study was to characterize 25 necrotoxigenic Escherichia coli type 1 (NTEC1), one necrotoxigenic E coli type 2 (NTEC2) and 16 non-necrotoxigenic E coli isolated, between 1979 and 1993, from feces, intestinal content or internal organs of dogs and cats using a uniform and standardized typing scheme, as previously described on NTEC1 and NTEC2 isolates from cattle, humans and pigs (Mainil et al, 1999). The results obtained by colony hybridization and PCR on the NTEC1 isolates were homogeneous: eighteen NTEC1 isolates harboured prs- and sfa/foc-related DNA sequences; five NTEC1 isolates harboured sfa/foc-related DNA sequences; one NTEC1 isolate harboured prs-related DNA sequences; and one was negative. The only NTEC2 isolate was also negative. Only a few NTEC1 isolates were positive for f17-, afa- or cdt-related DNA sequences. All NTEC1 and the NTEC2 isolates were haemolytic on blood agar and were resistant to the bactericidal activity of the serum (one exception). By contrast a very few produced an aerobactin or a colicin. The strains belonged to various serogroups and many could not be identified with the immunsera used. On the other hand all but one NTEC1 isolates belonged to biotype 9. The most typical profile identifed for NTEC1 from dogs and cats was: CNF1+Prs+S+Hly+Bio9+. The results obtained on the non-necrotoxigenic E. coli isolates were more heterogeneous: two of them harboured pap/prs- and sfa/foc-related DNA sequences; ten harboured pap/prs-related DNA sequences; and four, other DNA sequences. The results of the phenotypic assays were more heterogeneous also. NTEC1 strains were isolated from essentially young puppies and kitties (< 3 months for 16 out of 22), with sometimes older animals (up to 12 years). The digestive pathologies were non haemorrhagic diarrhea/enteritis essentially. When haemorrhagic diarrhea/enteritis were observed, other infectious agents were present or strongly suspected (parvovirus, Salmonella). Extraintestinal pathologies were septicaemic or systemic colibacillosis, with one case of necro-haemorrhagic metritis. NTEC1 and non-NTEC were not frequently antibiotic resistant. The most frequent resistant were to ampicillin, trimethoprim/sulfonamides and neomycin. [less ▲]

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See detailRegime alimentaire du Grand-Duc du désert, Bubo ascalaphus, dans la réserve naturelle de Mergueb (M'Sila, Algérie)
Biche, Mohamed; Sellami, Medhi; Libois, Roland ULg et al

in Alauda (2001), 69(4), 554-557

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical ... [more ▼]

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical basis (82 %) as well as in term of biomass (96 %) was Meriones shawi trouessarti (Gerbillidae). Other preys included Jaculus orientalis (Dipodidae), and two insectivores: Crocidura russula and Hemiechinus aethiopicus. Among the avifauna, only the Spanish sparrow (Passer hispaniolensis) was a significant part of the Eagle owl dietn especially in spring. Arthropods were represented by Scarabeidae in spring and Scorpionidae in summer but they played a minor role in the food of the Eagle owl. The originality of this diet lies in the absence of Brown hare (Lepus capensis) and the presence of only one specimen of the desert hedgehog. Although its food spectrum was very narrow in this site, the Eagle owl can be regarded as opportunistic as it concentrated on the most available prey: Meriones shawi. [less ▲]

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See detailMélanges Fritz Sturm, compte rendu d’ouvrage
Langenaken, Evelyne ULg

in Actualités du droit (2001)

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See detailModerate hypothermia during cardiopulmonary bypass reduces myocardial cell damage and myocardial cell death related to cardiac surgery.
Vazquez-Jimenez, J. F.; Qing, M.; Hermanns, B. et al

in Journal of the American College of Cardiology (2001), 38(4), 1216-23

OBJECTIVES: The goal of this study was to test the hypothesis that moderate hypothermia during cardiopulmonary bypass (CPB) provides myocardial protection by enhancing intra-myocardial anti-inflammatory ... [more ▼]

OBJECTIVES: The goal of this study was to test the hypothesis that moderate hypothermia during cardiopulmonary bypass (CPB) provides myocardial protection by enhancing intra-myocardial anti-inflammatory cytokine balance. BACKGROUND: Moderate hypothermia during experimental CPB stimulates production of interleukin-10 (IL10) and blunts release of tumor necrosis factor-alpha (TNFalpha). METHODS: Twelve young pigs were assigned to a temperature (T degrees ) regimen during CPB: moderate hypothermia (T degrees : 28 degrees C; n = 6) and normothermia (T degrees : 37 degrees C; n = 6). Intra-myocardial TNFalpha- and IL10-messenger RNA were detected by competitive reverse transcriptase polymerase chain reaction and quantification of cytokine synthesis by Western blot. Levels of cardiac troponin I (cTnI) in cardiac lymph and in arterial and coronary venous blood were examined during and after CPB. Myocardial cell damage was assessed by histologic and ultrastructural anomalies of tissue probes taken 6 h after CPB. RESULTS: Synthesis of IL10 was significantly higher, while that of TNFalpha was significantly lower, in pigs that were in moderate hypothermia during surgery than in the others. In contrast with normothermia, moderate hypothermia was also associated with significantly lower cumulative cardiac lymphatic flow during and after CPB, significantly lower lymphatic cTnI concentrations after CPB, significantly lower percentages of myocardial cell necrosis and a significantly lower score of ultrastructural anomalies of myocardial cells. While the percentage of apoptotic cells was not different between groups, the apoptosis/necrosis ratio tended to be higher in animals that were in moderate hypothermia during surgery. In all animals, TNFalpha synthesis correlated positively while IL10 production correlated negatively with necrosis and total cell death, respectively. CONCLUSIONS: Our results suggest that moderate hypothermia during CPB provides myocardial protection by enhancing intra-myocardial anti-inflammatory cytokine balance. [less ▲]

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See detailCatalytic asymmetric dihydroxylation of C,C double bonds with osmium tetroxide using selenoxides as co-oxidants
Krief, A.; Colaux, Catherine ULg

in Synlett (2001), (4), 501-504

Asymmetric dihydroxylation of olefins has been achieved in good yields and ee's using potassium osmate dihydrate (K2OsO2(OH)(4), the pre-oxidant), (DHQD)(2)PHAL (the chiral ligand), potassium carbonate ... [more ▼]

Asymmetric dihydroxylation of olefins has been achieved in good yields and ee's using potassium osmate dihydrate (K2OsO2(OH)(4), the pre-oxidant), (DHQD)(2)PHAL (the chiral ligand), potassium carbonate (the base) and selenoxides (the co-oxidants). Bath the yield and the ee proved to be pH dependent, the highest yield and ee being found at almost the same pH values. The rate of the reaction was found to be highly dependent upon the structure of the selenoxide used. Some representative examples involving aminoxides are presented for comparison. [less ▲]

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See detailSémiologie cardiaque dans l’espèce équine. 1- L’anamnèse et l’examen clinique.
Amory, Hélène ULg

in Pratique Vétérinaire Equine (2001), 33

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See detailB2 agonists cross the bovine placenta
Boutet, Philippe ULg; Uysterpruyst, C. H.; Degand, Guy ULg et al

in Pflügers Archiv : European Journal of Physiology (2001), 442(R41),

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See detailInventaire forestier régional et saisie électronique de données : une synergie prometteuse
Rondeux, Jacques ULg; Cavelier, Tristan

in Revue Forestière Française (2001), LIII(1), 81-87

The work done in connection with any regional or national inventory involves collecting huge amounts of increasingly diversified data. To reduce time lags before such data can be processed, we have ... [more ▼]

The work done in connection with any regional or national inventory involves collecting huge amounts of increasingly diversified data. To reduce time lags before such data can be processed, we have developed an encryption system on a HUSKY personal computer that is highly suitable to the sometimes adverse working conditions encountered in forests. The experiment has turned out to be extremely valuable and the system has been in use since mid-2000 for the purposes of the forest inventory in the Walloon Region. Considerable time savings are thus achieved and a highly elaborate computerised validation process and on-line aid to operators have significantly reduced the frequency of errors. [less ▲]

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See detailUse of multiple electrophysiological techniques to get insigh into the mode of action of an insecticide, fipronil
Grolleau, Françoise; Alix, Philippe ULg; Le Corronc, Hervé et al

in Veterinary and Human Toxicology (2001), 43(4), 238

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See detailSymptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. A double blind, prospective, placebo-controlled study.
Appelboom, T; Schuermans, J; Verbruggen, G et al

in Scandinavian Journal of Rheumatology (2001), 30(4), 242-7

OBJECTIVES: We compare the symptomatic effects of 300 or 600mg daily of ASU in patients with knee osteoarthritis. METHODS: A multicenter, double blind, study comparing a daily intake of 300mg or 600mg of ... [more ▼]

OBJECTIVES: We compare the symptomatic effects of 300 or 600mg daily of ASU in patients with knee osteoarthritis. METHODS: A multicenter, double blind, study comparing a daily intake of 300mg or 600mg of ASU and placebo. The study lasted 3 months and involved patients of both genders, aged 45 to 80 years and presenting with femoro-tibial knee osteoarthritis. The primary endpoint was NSAIDs and analgesics intake between D30 and D90. RESULTS: All efficacy parameters were significantly improved (p<0.01), in the two ASU groups compared to the placebo group. At D90, NSAIDs and analgesics intake decreased by more than 50% in 71% of the patients receiving ASU 300mg or 600mg, compared to 36% of the patients receiving placebo. From DO to D90 Lequesne's index dropped by 3.9 and 2.9 points in ASU 300mg and 600mg groups, respectively, against 1.6 in those receiving placebo. CONCLUSION: The efficacy of ASU at a dosage of 300mg/day and 600mg/day was consistently superior to that of placebo at all endpoints, with no differences observed between the two doses. [less ▲]

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See detailAbout the Photoionization of Methyl Chloride. A Threshold Photoelectron Spectroscopic and Photoionization Mass Spectrometric investigation.
Locht, Robert ULg; Leyh, Bernard ULg; Hoxha, A. et al

in Chemical Physics (2001), 272

The threshold photoelectron spectroscopic (TPES) and the photoionization mass spectrometric (PIMS) study of Methyl Chloride (CH3Cl) in the 8-20 eV photon energy is presented. The interpretation and ... [more ▼]

The threshold photoelectron spectroscopic (TPES) and the photoionization mass spectrometric (PIMS) study of Methyl Chloride (CH3Cl) in the 8-20 eV photon energy is presented. The interpretation and assignments are supported by ab initio calculations. The detailed analysis of the TPES shows numerous features in the Jahn-Teller split ground X2E(2A'-2A") state of CH3Cl+ and a new continuus band peaking at 13.4 eV. These were assigned to both direct ionization and autoionizing transitions. The transitions to the A2A1 and to the B2E states undergo a large enhancement ascribed to important autoionizing contributions. Based on the present calculations, the weak to very weak signals in the 19-26 eV photon energy range were mainly assigned to 2a1-1 ionization and to double excitations described essentially by 2e-2, 4a11 and 1e-1, 2e-1, 4a11 configurations. The PIMS study allowed us to investigate in detail the ionization and dissociation of CH3Cl+ into CH2+, CH3+, CHCl+ and CH2Cl+ from threshold up to 20 eV photon energy. At the onset, the CH3+, CHCl+ and CH2Cl+ fragment ion production is correlated to the ground state of CH3Cl+ and all fragment ions have to appear through dissociative autoionization from the 2e->3p Rydberg state. This interpretation is supported by the photoabsorption spectrum (PAS) measured recently in the same photon energy range. At higher energies, beside direct dissociation of the A2A1 and B2E states of CH3Cl+ autoionization also contributes to the fragmentation in all decay channels. For CH3+ the photoion-pair process is analyzed and detailed assignments are proposed on the basis of recent PAS data. [less ▲]

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See detailProfils de la progestérone des vaches zébu ‘Azawak’ et taurin ‘Gourunsi’ après induction de l’œstrus aux progestagènes combinés à la prostaglandine
Zongo, M.; Pitala, W.; Boly, H. et al

in Tropicultura (2001), 19(3), 131-134

Un dosage radioimmunologique a été utilisé pour mesurer les concentrations de progestérone chez les zébus “Azawak” (Bos indicus, n = 6) et taurins Gourunsi (Bos taurus, n = 5) après induction de l'œstrus ... [more ▼]

Un dosage radioimmunologique a été utilisé pour mesurer les concentrations de progestérone chez les zébus “Azawak” (Bos indicus, n = 6) et taurins Gourunsi (Bos taurus, n = 5) après induction de l'œstrus. Les observations ont été menées sur 11 vaches non gestantes (groupe I composé de 3 zébus Azawak et 3 taurins Gourunsi; groupe II composé de 3 zébus Azawak et 2 taurins Gourunsi), soumises à un traitement hormonal reposant sur l’administration d’un implant de progestagène, d’une injection de prostaglandine F2alpha et, pour une partie des femelles (groupe I), d’une injection de PMSG. Les implants ont été placés sous la peau de la face externe de l’oreille et maintenus pendant une période de 10 jours. Au 8e jour du traitement, les femelles ont reçu une injection intramusculaire de prostaglandine F2 (5 mg/100 kg) et au 10e jour, au moment du retrait, une injection de PMSG (400 UI/300 kg de poids vif) a été pratiquée sur les animaux du groupe I. Chez les taurins Gourunsi et chez les zébus Azawak ayant reçu l’injection de PMSG, le traitement a été suivi d’un œstrus dans 2 cas sur 3. Chez les animaux appartenant au groupe II, l’œstrus ne fut observé chez aucun taurin et seulement chez 1 des 3 zébus. Les concentrations de progestérone mesurées au cours des phases lutéales qui ont suivi sont restées faibles chez les taurins Gourunsi. Chez les zébus Azawak, les concentrations se sont révélées plus élévées chez les femelles ayant reçu l’injection de PMSG (6,0 +/- 1,2 ng/ml) que chez celles qui n’avaient pas reçu (3,2 +/- 0,8 ng/ml). [less ▲]

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See detailEssais d’induction artificielle de la lactation chez des génisses âgées de 6 a 7 mois
Nchare, A.; Salaheddine, M.; Desbuleux, H. et al

in Annales de Médecine Vétérinaire (2001), 145(6, Suppl. S), 365-371

The rates of successful gene's manipulations are very low in domestic mammals. In addition the period between generations in cows is long. Artificial induction of lactation in young animals could improve ... [more ▼]

The rates of successful gene's manipulations are very low in domestic mammals. In addition the period between generations in cows is long. Artificial induction of lactation in young animals could improve manipulation yield for genes what are expressed in the udder, by anticipating the control of transgen expression in milk, a long time before the beginning of the milk production in normal condition. Using this method, the early selection of real transgenic animals would be possible. Between November 1999 and April 2000, lactation was induced in non-transgenic heifers aged from 6 to 7 months, in 2 trials based on short time hormonal treatment, with the goal of verifying the efficiency of the technique on immature heifers, and setting up a simple and reliable treatment scheme applicable on young animals. Interesting lactations (35 to 974 ml/day) were obtained, but the milk yield was low compared to adult performances. Results of the 2 trials were different, in relation with the galenical form of progesterone used and the frequency of drugs administration. So, these trials provide an efficient treatment scheme for induction of lactation in young heifers. [less ▲]

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See detailLes sanctions administratives dans les communes : en route vers le droit communal armé
Masset, Adrien ULg

in Journal des Tribunaux (2001), 6031(2001), 833-838

La nouvelle loi belge du 13 mai 1999 permet désormais aux communes de réglementer une série de comportements en en assurant le respect par le recours à des sanctions administratives, alors qu’auparavant ... [more ▼]

La nouvelle loi belge du 13 mai 1999 permet désormais aux communes de réglementer une série de comportements en en assurant le respect par le recours à des sanctions administratives, alors qu’auparavant ces sanctions ne pouvaient être que pénales; la loi nouvelle offre aussi aux communes des pouvoirs de police administrative plus étendus; cette loi donne le ton d’une dépénalisation dans les communes au profit d’un droit administrativo-pénal [less ▲]

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See detailRépercussions systémiques des infections parodontales: définition d'un nouvel index parodontal
Geerts, Sabine ULg; Rompen, Eric ULg

in Actualités Dentaires de l'Université de Liège (2001), 207

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See detailPresence of Oestrogen Receptor Type Beta in Human Retina
Munaut, Carine ULg; Lambert, Vincent ULg; Noël, Agnès ULg et al

in British Journal of Ophthalmology (2001), 85(7), 877-82

BACKGROUND/AIMS: Recent studies have demonstrated the existence of two oestrogen receptor subtypes alpha (ORalpha) and beta (ORbeta) with significant differences of expression among organs. Since ... [more ▼]

BACKGROUND/AIMS: Recent studies have demonstrated the existence of two oestrogen receptor subtypes alpha (ORalpha) and beta (ORbeta) with significant differences of expression among organs. Since important pathologies of human eye could be linked to hormonal status, the expression of ORbeta in ocular posterior segment was sought. METHODS: Immunohistochemical localisation of ORbeta and ORalpha protein and detection of OR mRNAs by reverse transcription-polymerase chain reaction (RT-PCR) were performed in macular and extramacular regions of the retina and in the choroid on male and female donors eyes. RESULTS: ORbeta protein was localised in the ganglion cell layer and in the choroid. At the transcriptional level, mRNA for ORbeta and for ORalpha were both present. Local differences in the expression level were observed, however, suggesting the possibility of variation in the ratio of ORalpha v ORbeta. CONCLUSIONS: The coexistence of two oestrogen receptor subtypes in the human ocular posterior segment raises acute questions about their potential physiological role, but offers a perspective for preferential targeting of a specific receptor subtype. [less ▲]

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See detailGenetic markers of osteoarticular disorders: facts and hopes.
Brandi, M L; Gennari, L; Cerinic, M M et al

in Arthritis Research (2001), 3(5), 270-80

Osteoarthritis and osteoporosis are the two most common age-related chronic disorders of articular joints and skeleton, representing a major public health problem in most developed countries. Apart from ... [more ▼]

Osteoarthritis and osteoporosis are the two most common age-related chronic disorders of articular joints and skeleton, representing a major public health problem in most developed countries. Apart from being influenced by environmental factors, both disorders have a strong genetic component, and there is now considerable evidence from large population studies that these two disorders are inversely related. Thus, an accurate analysis of the genetic component of one of these two multifactorial diseases may provide data of interest for the other. However, the existence of confounding factors must always be borne in mind in interpreting the genetic analysis. In addition, each patient must be given an accurate clinical evaluation, including family history, history of drug treatments, lifestyle, and environment, in order to reduce the background bias. Here, we review the impact of recent work in molecular genetics suggesting that powerful molecular biology techniques will soon make possible both a rapid accumulation of data on the genetics of both disorders and the development of novel diagnostic, prognostic, and therapeutic approaches. [less ▲]

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See detailLe portage asymptomatique de Microsporum canis chez le chat
Mignon, Bernard ULg; Brouta, F.; Descamps, F. et al

in Annales de Médecine Vétérinaire (2001), 145

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See detailA Parametric Distance Function Approach for Malmquist Productivity Index Estimation
Fuentes, Hugo J.; Grifell-Tatjé, Emili; Perelman, Sergio ULg

in Journal of Productivity Analysis (2001), 15

Malmquist indexes of productivity are generally estimated using index number techniques or non-parametric frontier approaches. The aim of this paper is to showthat Malmquist indexes can be estimated in a ... [more ▼]

Malmquist indexes of productivity are generally estimated using index number techniques or non-parametric frontier approaches. The aim of this paper is to showthat Malmquist indexes can be estimated in a similar way using parametric-deterministic or parametric-stochastic frontier approaches. To allow a multi-output multi-input technology and for technical change in production, we adopt an output distance function which is specified in a translog form. We then show that using the estimated parameters, several radial distance functions can be calculated and combined in order to estimate and decompose the productivity index. Finally, this approach is applied to a panel of Spanish insurance companies. The main results confirm those generally obtained for financial services: very low rates of growth and technical change in spite of a rapid deregulation process and expansion of activity. [less ▲]

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See detail33 RENO: A European surveillance registry of coronary brachytherapy with the NovosteTM Beta-CathTM System
Coen, V.; Sauerwein; Orrechia et al

in Radiotherapy & Oncology (2001), 60(supp 1), 12

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See detailA comparison of blade tip timing data analysis methods
Carrington, Ian B; Wright, Jan Robert; Cooper, Jonathan E et al

in Proceedings of the Institution of Mechanical Engineers - Part G - Journal of Aerospace Engineering (2001), 215(6), 301-312

The experimental determination of the vibration characteristics of rotating engine blades is very important for fatigue failure considerations. One of the most promising techniques for measuring the ... [more ▼]

The experimental determination of the vibration characteristics of rotating engine blades is very important for fatigue failure considerations. One of the most promising techniques for measuring the frequency of blade vibrations is blade tip timing. In this paper, three vibration analysis methods were specifically formulated and applied to the tip timing problem for the first time, using data obtained from a simple mathematical blade tip timing simulation. The results from the methods were compared statistically in order to determine which of the techniques is more suitable. One of the methods, the global autoregressive instrumental variables approach, produced satisfactory results at realistic noise levels. However, all of the techniques produced biased results under certain circumstances. [less ▲]

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See detailEffect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group.
McClung, M R; Geusens, P; Miller, P D et al

in New England Journal of Medicine [=NEJM] (2001), 344(5), 333-40

BACKGROUND: Risedronate increases bone mineral density in elderly women, but whether it prevents hip fracture is not known. METHODS: We studied 5445 women 70 to 79 years old who had osteoporosis ... [more ▼]

BACKGROUND: Risedronate increases bone mineral density in elderly women, but whether it prevents hip fracture is not known. METHODS: We studied 5445 women 70 to 79 years old who had osteoporosis (indicated by a T score for bone mineral density at the femoral neck that was more than 4 SD below the mean peak value in young adults [-4] or lower than -3 plus a nonskeletal risk factor for hip fracture, such as poor gait or a propensity to fall) and 3886 women at least 80 years old who had at least one nonskeletal risk factor for hip fracture or low bone mineral density at the femoral neck (T score, lower than -4 or lower than -3 plus a hip-axis length of 11.1 cm or greater). The women were randomly assigned to receive treatment with oral risedronate (2.5 or 5.0 mg daily) or placebo for three years. The primary end point was the occurrence of hip fracture. RESULTS: Overall, the incidence of hip fracture among all the women assigned to risedronate was 2.8 percent, as compared with 3.9 percent among those assigned to placebo (relative risk, 0.7; 95 percent confidence interval, 0.6 to 0.9; P=0.02). In the group of women with osteoporosis (those 70 to 79 years old), the incidence of hip fracture among those assigned to risedronate was 1.9 percent, as compared with 3.2 percent among those assigned to placebo (relative risk, 0.6; 95 percent confidence interval, 0.4 to 0.9; P=0.009). In the group of women selected primarily on the basis of nonskeletal risk factors (those at least 80 years of age), the incidence of hip fracture was 4.2 percent among those assigned to risedronate and 5.1 percent among those assigned to placebo (P=0.35). CONCLUSIONS: Risedronate significantly reduces the risk of hip fracture among elderly women with confirmed osteoporosis but not among elderly women selected primarily on the basis of risk factors other than low bone mineral density. [less ▲]

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See detailLa lecture littéraire : le pour et le contre
Dumortier, Jean-Louis ULg

in Education-Formation (2001), 262

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See detailSurvival, gap formation and recovery dynamics in grassland ecosystems exposed to heat extremes: the role of species richness.
Van Peer, L; Nijs, I; Bogaert, Jan ULg et al

in Ecosystems (2001), 4(8), 797-806

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See detailA control strategy for controllable series capacitor in electric power systems
Ghandhari, Mehrdad; Andersson, Goran; Pavella, Mania ULg et al

in Automatica (2001), 37

It has been veri"ed that a controllable series capacitor with a suitable control scheme can improve transient stability and help to damp electromechanical oscillations. A question of great importance is ... [more ▼]

It has been veri"ed that a controllable series capacitor with a suitable control scheme can improve transient stability and help to damp electromechanical oscillations. A question of great importance is the selection of the input signals and a control strategy for this device in order to damp power oscillations in an e!ective and robust manner. Based on Lyapunov theory a control strategy for damping of electromechanical power oscillations in a multi-machine power system is derived. Lyapunov theory deals with dynamical systems without inputs. For this reason, it has traditionally been applied only to closed-loop control systems, that is, systems for which the input has been eliminated through the substitution of a predetermined feedback control. However, in this paper, we use Lyapunov function candidates in feedback design itself by making the Lyapunov derivative negative when choosing the control. This control strategy is called control Lyapunov function for systems with control inputs. Also, two input signals for this control strategy are used. The "rst one is based on local information and the second one on remote information derived by the single machine equivalent method. [less ▲]

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See detailTreatment of drug-induced toxic epidermal necrolysis (Lyell’s syndrome) with intravenous human immunoglobulins
Paquet, Philippe ULg; JACOB, Eric; Damas, Pierre ULg et al

in Burns : Journal of the International Society for Burn Injuries (2001), 27(6), 652-655

Toxic epidermal necrolysis (TEN) is a rare drug-induced life-threatening disease. Currently, the disease is only treated by supportive and antiseptic measures. Quite recently intravenous immunoglobulins ... [more ▼]

Toxic epidermal necrolysis (TEN) is a rare drug-induced life-threatening disease. Currently, the disease is only treated by supportive and antiseptic measures. Quite recently intravenous immunoglobulins (IG) were shown to be a promising TEN treatment. The rationale for their use is based on the fact that keratinocyte apoptosis in TEN involves the CD95 (APO-1/Fas) cell surface receptor–ligand system. We successfully treated a TEN patient with high dose of intravenous IG. The clinical recovery appeared exceptionally rapid. Immunohistochemistry showed that the IG action probably developed on the CD95 receptor–ligand system at the keratinocytes surface. [less ▲]

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See detailThe use of additives to prepare low-density xerogels
Alié, Christelle ULg; Pirard, René ULg; Lecloux, A. J. et al

in Journal of Non-Crystalline Solids (2001), 285

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See detailWell-ordered spherical mesoporous materials CMI-1 synthesized via an assembly of decaoxyethylene cetyl ether and TMOS
Blin, Jean-Luc; Léonard, Alexandre ULg; Su, Bao-Lian

in Chemistry of Materials (2001), 13(10), 3542-3553

Well-ordered spherical CMI-1 mesoporous materials with a hexagonal arrangement of channels, analogous to MCM-41, have been directly synthesized by variation of the weight percentage of decaoxyethylene ... [more ▼]

Well-ordered spherical CMI-1 mesoporous materials with a hexagonal arrangement of channels, analogous to MCM-41, have been directly synthesized by variation of the weight percentage of decaoxyethylene cetyl ether [C 16(EO) 10] in aqueous solution. XRD, TEM, SEM, and nitrogen adsorption-desorption results led us to propose two different synthesis pathways for surfactant concentrations higher and lower than 30 wt %, respectively. For samples obtained with an elevated surfactant concentration (>30 wt %), in addition to the possible perturbation induced by methanol released in low amount during the hydrolysis of TMOS, other factors such as the interactions of the silica source with hydrophilic chain heads of surfactant molecules should also disturb the preformed hexagonal micelle array, and disordered wormhole mesostructured materials (DWM), analogous to MSU, are obtained. For the synthesis with a C 16(EO) 10 concentration less than 30 wt %, a cooperative mechanism, which involves the polymerization of silica source and the interface interactions between the hydroxyl groups of silica source produced from the hydrolysis of TMOS and hydrophilic chain heads of surfactant molecules which are present in the single rod micelle form, has been evidenced, leading to well-ordered CMI-1 materials with hexagonal arrangement of their channels. [less ▲]

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See detailEffect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.
Neer, R M; Arnaud, C D; Zanchetta, J R et al

in New England Journal of Medicine [=NEJM] (2001), 344(19), 1434-41

BACKGROUND: Once-daily injections of parathyroid hormone or its amino-terminal fragments increase bone formation and bone mass without causing hypercalcemia, but their effects on fractures are unknown ... [more ▼]

BACKGROUND: Once-daily injections of parathyroid hormone or its amino-terminal fragments increase bone formation and bone mass without causing hypercalcemia, but their effects on fractures are unknown. METHODS: We randomly assigned 1637 postmenopausal women with prior vertebral fractures to receive 20 or 40 microg of parathyroid hormone (1-34) or placebo, administered subcutaneously by the women daily. We obtained vertebral radiographs at base line and at the end of the study (median duration of observation, 21 months) and performed serial measurements of bone mass by dual-energy x-ray absorptiometry. RESULTS: New vertebral fractures occurred in 14 percent of the women in the placebo group and in 5 percent and 4 percent, respectively, of the women in the 20-microg and 40-microg parathyroid hormone groups; the respective relative risks of fracture in the 20-microg and 40-microg groups, as compared with the placebo group, were 0.35 and 0.31 (95 percent confidence intervals, 0.22 to 0.55 and 0.19 to 0.50). New nonvertebral fragility fractures occurred in 6 percent of the women in the placebo group and in 3 percent of those in each parathyroid hormone group (relative risk, 0.47 and 0.46, respectively [95 percent confidence intervals, 0.25 to 0.88 and 0.25 to 0.861). As compared with placebo, the 20-microg and 40-microg doses of parathyroid hormone increased bone mineral density by 9 and 13 more percentage points in the lumbar spine and by 3 and 6 more percentage points in the femoral neck; the 40-microg dose decreased bone mineral density at the shaft of the radius by 2 more percentage points. Both doses increased total-body bone mineral by 2 to 4 more percentage points than did placebo. Parathyroid hormone had only minor side effects (occasional nausea and headache). CONCLUSIONS: Treatment of postmenopausal osteoporosis with parathyroid hormone (1-34) decreases the risk of vertebral and nonvertebral fractures; increases vertebral, femoral, and total-body bone mineral density; and is well tolerated. The 40-microg dose increased bone mineral density more than the 20-microg dose but had similar effects on the risk of fracture and was more likely to have side effects. [less ▲]

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See detailGene structure and promoter function of a teleost ribosomal protein: a tilapia (Oreochromis mossambicus) L18 gene
Molina, Alfredo; Iyengar, Arati; Marins, Luis F. et al

in Biochimica et Biophysica Acta (2001), 1520(3), 195-202

We have cloned and characterized a tilapia (Oreochromis mossambicus) L18 ribosomal protein gene, including the complete transcribed region and 488 bp of upstream regulatory sequences. We have also ... [more ▼]

We have cloned and characterized a tilapia (Oreochromis mossambicus) L18 ribosomal protein gene, including the complete transcribed region and 488 bp of upstream regulatory sequences. We have also isolated two L18 cDNAs from another tilapia (Oreochromis niloticus) with a few conservative nucleotide differences. Our results suggest the presence of two genes in both species. Reporter constructs were tested for transient expression in CV1 cells and in microinjected zebrafish and tilapia embryos. The tilapia L18 promoter was able to drive expression of the reporter gene in all three experiments, with no apparent preference for a particular tissue. The tilapia L18 promoter is therefore likely to be a powerful tool to drive tissue-independent gene expression in fish. [less ▲]

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See detailEugène Monseur (1860-1912)
Boutier, Marie-Guy ULg

in Wallonnes : Chronique de la Société de Langue et de Littérature Wallonnes (2001), (1),

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See detailLa théorie d’après Hjelmslev
Badir, Sémir ULg

in Janus. Quaderni del Circolo Glossematico (2001), 2

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See detailPalaeogeographic and palaeoenvironmental characteristics of major marine incursions in northwestern Europe during the Westphalian C (Bolsovian).
Dusar, M; Paproth, E; Streel, Maurice ULg et al

in Geologica Belgica (2001), (2000)3(3-4), 331-347

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See detailLe portfolio : un outil de socio-construction pour scripteur en devenir
Baye, Ariane ULg; Denooz, Régine

in Caractères (2001), 3

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See detailAnalysis Of The Chromosome Sequence Of The Legume Symbiont Sinorhizobium Meliloti Strain 1021
Capela, Delphine; Barloy-Hubler, Frédérique; Gouzy, Jérôme et al

in Proceedings of the National Academy of Sciences of the United States of America (2001), 98(17),

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See detailOral vitamin C attenuates acute ischaemia-reperfusion injury in skeletal muscle.
Kearns, S. R.; Moneley, D.; Murray, P. et al

in Journal of Bone & Joint Surgery, British Volume (2001), 83(8), 1202-6

Ischaemia-reperfusion injury (IRI) is caused by endothelial and subendothelial damage by neutrophil-derived oxidants. Vitamin C is an antioxidant which attenuates endothelial injury after IRI. Our aim was ... [more ▼]

Ischaemia-reperfusion injury (IRI) is caused by endothelial and subendothelial damage by neutrophil-derived oxidants. Vitamin C is an antioxidant which attenuates endothelial injury after IRI. Our aim was to evaluate the effect of oral vitamin C in the prevention of IRI in skeletal muscle. We used a model of cross-clamping (3 hours) and reperfusion (1 hour) of the cremaster muscle in rats. Muscle function was assessed electrophysiologically by electrical field stimulation. Infiltration by neutrophils was determined by the activity of tissue myeloperoxidase (MPO) and tissue oedema by the wet-to-dry ratio. Neutrophil respiratory burst activity was measured in control animals and groups pretreated with vitamin C. IRI significantly decreased muscle function and increased muscle neutrophil MPO activity and muscle oedema. Pretreatment with vitamin C preserved muscle function and reduced tissue oedema and neutrophil infiltration. Neutrophil respiratory burst activity was reduced in the group treated with vitamin C compared with the control group. We conclude that pretreatment with oral vitamin C protects against acute muscle IRI, possibly by attenuating neutrophil respiratory burst activity. [less ▲]

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See detailBinding and multiple instantiation in a distributed network of spiking nodes
Sougné, Jacques ULg

in Connection Science (2001), 13(2), 99-126

An implementation of a distributed connectionist network of spiking neuron-like elements is presented. Spiking nodes fire at a precise moment and transmit their activation, with particular strenghts and ... [more ▼]

An implementation of a distributed connectionist network of spiking neuron-like elements is presented. Spiking nodes fire at a precise moment and transmit their activation, with particular strenghts and delays, to nodes connected to them. Wen the potential of the node reaches a particular threshold, it emits a spike. Thereafter, the potential is reset to a resting value. The receiving nodes accumulate potential, but also, slowly lose their potential through decay. As with real neurons, after firing there is a short refractory period during which the node will be completely insensitive to incoming signals, after which its sensitivity will slowly increase. Precise timing properties are used to represent symbols in a distributed manner and also to solve the problems of variable binding and multiple instantiation. Several predictions about human short-term memory, predicate processing, complex reasoning and multiple instantiation arise from this model. This network shows how symbolic processing can be achieved using neurobiologically and psychologically plausible mechanisms that also have the advantages of generalization and noise tolerance found in connectionist networks. [less ▲]

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See detailEn Bloc Excision of Nonpalpable Breast Lesions Using the Advanced Breast Biopsy Instrumentation System: An Alternative to Needle Guided Surgery?
Lifrange, Eric ULg; Dondelinger, R. F.; Fridman, Viviana ULg et al

in European Radiology (2001), 11(5), 796-801

This study was prospectively conducted to evaluate the clinical potential of the advanced breast biopsy instrumentation (ABBI) system as an alternative to needle localization and open surgery in the ... [more ▼]

This study was prospectively conducted to evaluate the clinical potential of the advanced breast biopsy instrumentation (ABBI) system as an alternative to needle localization and open surgery in the management of nonpalpable breast lesions (NPBL). One hundred and eighty-six consecutive patients were referred for management of NPBL. Thirty-six underwent an ABBI procedure, offered as a first step before possible surgery for lesions which would in any case have required complete excision. The 18 patients with a malignant ABBI biopsy underwent re-excision of the biopsy site and axillary dissection was carried out in cases of infiltrating carcinoma. The other 150 patients underwent image-guided needle biopsy. Following these procedures, 60/150 (40%) patients underwent needle-guided surgery. Finally, 96/186 (51%) patients required complete excision. A total of 43 benign lesions and 53 carcinomas were confirmed. Thirty-six out of 96 (38%) excisions were obtained with the ABBI system; 17/43 (40%) benign lesions and 11/53 (21%) carcinomas were completely removed with the ABBI system. Out of 9 malignant specimens with a pathological size less than 10 mm, 5/9 (55%) had tumor-free margins and in 8/9 (89%) no residual disease was found at re-excision. The preliminary results of this study suggest that, in selected cases, en bloc excision using the ABBI procedure could be an alternative to conventional surgery. [less ▲]

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See detailA world monograph of the lichen genus Gyalectidium (Gomphillaceae)
Ferraro, Lidia Itati; Lücking, Robert; Sérusiaux, Emmanuël ULg

in Botanical Journal of the Linnean Society (2001), 137

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See detailChronic rupture of abdominal aortic aneurysm manifesting as crural neuropathy.
Defraigne, Jean-Olivier ULg; SakalihasanN, Natzi ULg; LAVIGNE, Jean-Paul ULg et al

in Annals of Vascular Surgery (2001), 15(3), 405-11

Chronic rupture of abdominal aortic aneurysm (AAA) resulting in unusual clinical manifestations can occur if the resistance of structures surrounding the aorta is sufficient to contain hemorrhage. In this ... [more ▼]

Chronic rupture of abdominal aortic aneurysm (AAA) resulting in unusual clinical manifestations can occur if the resistance of structures surrounding the aorta is sufficient to contain hemorrhage. In this report, we describe five cases of chronic ruptured AAA in which the presenting feature was crural neuropathy. All patients were male with a mean age of 74 +/- 1.8 years. At the time of presentation, crural neuropathy had been ongoing for 3 to 9 weeks. In three cases, AAA was not initially suspected because an inadequate clinical examination was performed (not in the vascular surgery department) and because of the small diameter of the aorta in relation to the patient's morphology. Two patients had one episode of hypotension that was wrongly attributed to vagal attack. Abdominal CT scanning was always diagnostic of chronic rupture. In two cases, rupture was associated with erosion of the body of one or more vertebrae and laboratory evidence of inflammation, i.e., increase in sedimentation rate and fibrinogen level. The mean diameter of the AAA was 7.1 +/- 0.9 cm (range 5-10 cm). All patients underwent midline laparotomy, which was performed under emergency conditions in two cases, under semi-emergency conditions in one case, and electively in two cases. Perforation was consistently located on the posterolateral wall of the aorta and varied from 1 to 3 cm in length. Repair was performed using an aortobifemoral prosthesis in four cases, and a straight tube in one case. The patient who underwent emergency surgery died 4 days after the procedure. The remaining four patients recovered uneventfully and were discharged after 10 days. In the elderly, ruptured AAA should be included in the differential diagnosis of crural neuropathy. An episode of hypotension, regardless of its duration, in an elderly patient should be given serious consideration as a possible sign of ruptured AAA with ongoing retroperitoneal hemorrhage. [less ▲]

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See detailA self-consistent model of the Jovian auroral thermal structure
Grodent, Denis ULg; Waite, J. Hunter; Gérard, Jean-Claude ULg

in Journal of Geophysical Research (2001), 106(A7), 12933-12952

A one-dimensional (1-D) model coupling a two-stream electron transport model of energy deposition with a 1-D thermal conduction model has been developed. It is applied to investigate the links between ... [more ▼]

A one-dimensional (1-D) model coupling a two-stream electron transport model of energy deposition with a 1-D thermal conduction model has been developed. It is applied to investigate the links between auroral heat input and the vertical temperature of Jupiter's upper atmosphere. Two energy distributions meant to reproduce the emissions of a diffuse and a discrete aurora are used to evaluate the importance of the energy spectrum of the incident electrons for the thermal balance of Jupiter's auroral thermosphere. The values of observable quantities such as the altitude of the H-2 emission peak, thermal infrared (LR), ultraviolet (UV) emissions, and temperatures associated with various optical signatures are used to constrain the parameters of these distributions. It is shown that the high-energy component of these energy distributions heats a region of the homosphere between 10(-4) and 10(-6) bar and mainly controls the H-2 temperature and the far-UV (FUV) emission. A 3-keV soft electron component is necessary to heat the region directly above the homopause, between 10(-6) and 10(-9) bar. It has a large influence on the H-2 and H-3(+) temperatures and on the H-3(+) near-IR(NIR) emission. It is used in conjunction with a weak 100 eV component which is responsible for heating the thermosphere, from 10(-9) to 10(-12) bar and exerts a control on the exospheric temperature. The calculated temperatures, UV, and IR emissions suggest that the model probably misses a nonparticle heat source in the 10(-5) bar region, that is expected to balance the strong hydrocarbon cooling. Sensitivity tests are performed to evaluate the importance of the parameters of the energy distributions. They show that the FUV color ratio increases with the characteristic energy (or high-energy cutoff) of the high-energy component, while the H-2 rovibrational temperature varies inversely. A trade-off is therefore necessary for these two parameters to simultaneously meet their observational constraints. Further tests demonstrate the essential thermostatic role played by H-3(+), which regulates the net heating in the thermosphere. An increased eddy diffusion reproduces the effect of a possible auroral upwelling of methane but gives rise to an H-2 temperature smaller than the observed value. [less ▲]

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See detailQuelques données sur les différentes prises en charge des délinquants sexuels dans les pays de l'Union européenne
Cornet, Jean-Philippe; Mormont, Christian ULg; Michel, Aude

in Annales Médico Psychologiques (2001), 159(9), 639-644

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See detailValue of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: results of the European Organization for Research and Treatment of Cancer 58881 randomized phase III trial.
Millot, F; Suciu, S; Philippe, N et al

in Journal of Clinical Oncology (2001), 19

PURPOSE: The European Organization for Research and Treatment of Cancer 58881 study was designed to test in a prospective multicentric randomized trial the value of high-dose (HD) intravenous (IV ... [more ▼]

PURPOSE: The European Organization for Research and Treatment of Cancer 58881 study was designed to test in a prospective multicentric randomized trial the value of high-dose (HD) intravenous (IV) cytarabine (Ara-C) added to HD IV methotrexate (MTX) to reduce the incidence of CNS and systemic relapses in children with increased-risk acute lymphoblastic leukemia (ALL) or stage III and IV lymphoblastic lymphoma treated with a Berlin-Frankfurt-Munster (BFM)-based regimen. PATIENTS AND METHODS: After completion of induction-consolidation phase, children with increased-risk (risk factor > 0.8 or T-lineage) ALL or stage III and IV lymphoblastic lymphoma were randomized to receive four courses of HD MTX (5 g/m(2) over 24 hours every 2 weeks) and four intrathecal administrations of MTX (Arm A) or the same treatment schedule with additional HD IV Ara-C (1 g/m(2) in bolus injection 12 and 24 hours after the start of each MTX infusion) (Arm B). RESULTS: Between January 1990 and January 1996, 653 patients with ALL (593 patients) or lymphoblastic lymphoma (60 patients) were randomized: 323 were assigned to Arm A (without Ara-C) and 330 to Arm B (with Ara-C). A total of 190 events (177 relapses and 13 deaths without relapse) were reported, and the median follow up was 6.5 years (range, 2 to 10 years). The incidence rates of CNS relapse were similar in both arms whether isolated (5.6% and 3.3%, respectively) or combined (5.3% and 4.6%, respectively). The estimated 6-year disease-free survival (DFS) rate was similar (log-rank P =.67) in the two treatment groups: 70.4% (SE = 2.6%) in Arm A and 71.0% (SE = 2.5%) in Arm B. The 6-year DFS rate was similar for ALL and LL patients: 70.2% (SE = 1.9%) versus 76.3% (SE = 5.6%). CONCLUSION: Prevention of CNS relapse was satisfactorily achieved with HD IV MTX and intrathecal injections of MTX in children with increased-risk ALL or stage III and IV lymphoblastic lymphoma treated with our BFM-based treatment protocol in which cranial irradiation was omitted. Disappointingly, with the dose schedule used in this protocol, HD Ara-C added to HD MTX, although well tolerated, failed to further decrease the incidence of CNS relapse or to improve the overall DFS. [less ▲]

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See detailLe travailleur adoptant
Kefer, Fabienne ULg; Barth, D.

in Actualités du Droit (2001)

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See detailLocation and Phenotype of Proliferating T cells in Secondary Lymph Follicles
Hoshi, S.; Bouzahzah, F.; Mancini, I. et al

in Journal of Clinical and Experimental Hematopathology [=JCEH] (2001), 42

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See detailValidation d'un test d'évaluation du comportement gestuel du patient lombalgique chronique
Vanderthommen, Marc ULg; Boulanger, A.S.; DEFAWEUX, Michel ULg et al

in Annales de Réadaptation et de Médecine Physique (2001), 44

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See detailConsidérations sur le taux du ressort lorsque les bases de détermination de la valeur du litige font défaut
Boularbah, Hakim ULg

in Revue de Droit Judiciaire et de la Preuve = Tijdschrift voor Procesrecht en Bewijsrecht (2001)

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See detailSmoothed nonparametric maximum likelihood estimation of the risk distribution underlying bonus-malus systems
Denuit, Michel; Lambert, Philippe ULg

in Proceedings of the Casualty Actuarial Society (2001), LXXXVIII

Mixed Poisson distributions are widely used for modeling claim counts when the portfolio is thought to be heterogeneous. The risk (or mixing) distribution then represents a measure of this heterogeneity ... [more ▼]

Mixed Poisson distributions are widely used for modeling claim counts when the portfolio is thought to be heterogeneous. The risk (or mixing) distribution then represents a measure of this heterogeneity. The aim of this paper is to use a variant of the Patilea and Rolin [15] smoothed version of the Simar [20] Non-Parametric Maximum Likelihood Estimator of the risk distribution in the mixed Poisson model. Empirical results based on two data sets from automobile third-party liability insurance demonstrate the relevance of this approach. The design of merit-rating schemes is discussed in the second part of the paper. [less ▲]

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See detailAn On-line Glossary as a way to foster the construction of a common culture among urban experts, stakeholders and decision-makers
Teller, Jacques ULg

in Construction Innovation (2001), 1/4

Negotiation and public participation are a key aspect of present urban development projects. Argumentation support tools, based on the Toulmin logic, have often been presented as a way to increase the ... [more ▼]

Negotiation and public participation are a key aspect of present urban development projects. Argumentation support tools, based on the Toulmin logic, have often been presented as a way to increase the accountability of the debates between the different urban actors. It should still be assumed that any collaborative decision making requires some common culture to make the dialogue possible and constructive. Such a common understanding of basic terms, references and methods is often missing in present-day urban disputes, especially when complex issues like cultural heritage are at stake. The present paper discusses the relevancy of Web Glossaries as a way to build up such a common culture among urban experts, stakeholders and decision-makers. [less ▲]

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