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See detailEssai d'utilisation du meloxicam (Metacam® Boehringer Ingelheim) chez le pigeon voyageur
Marlier, Didier ULg; Jonckers, Frédéric; Vindevogel, Henri ULg

in Annales de Médecine Vétérinaire (1997), 141

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See detailAge model estimation in paleoclimatic research : fuzzy regression and radiocarbon uncertainties
Boreux, Jean-Jacques ULg; Pesti, G.; Duckstein, L. et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (1997), 128(1), 29-37

A fuzzy linear regression-based method to relate the depth and age of sediment layers is described. Because algae, moss or local plants respond to climatic change, the age and depth of sediment layers are ... [more ▼]

A fuzzy linear regression-based method to relate the depth and age of sediment layers is described. Because algae, moss or local plants respond to climatic change, the age and depth of sediment layers are interrelated variables but the link between them is often imprecise. In most cases, due to the limited number of layers in a core (i.e., small number of data points), estimation of the slope and uncertainties in classical regression analysis does not take into account the uncertainties in radiocarbon dating. Here, fuzzy linear regression, which may be applied even to a very small data set, is utilized. The method, illustrated through a practical example, with eight data points, appears to be a promising tool in stratigraphic studies to link sediment age to layer depth and takes into account uncertainties from radiocarbon dating. [less ▲]

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See detailFibres alimentaires chez le chien : influence de l'incorporation de pulpes de betterave ou de chicorée sur la digestibilité des nutriments et les concentrations plasmatiques de plusieurs métabolites
Diez, Marianne ULg; Hornick, Jean-Luc ULg; Van Eenaeme, Christian ULg et al

in Revue de Médecine Vétérinaire (1997), 148

Cette étude relate les effets de la distribution de deux rations enrichies en pulpes de betterave ou de chicorée (7 p.100 ADF dans la matière sèche) en comparaison à une ration témoin sur les paramètres ... [more ▼]

Cette étude relate les effets de la distribution de deux rations enrichies en pulpes de betterave ou de chicorée (7 p.100 ADF dans la matière sèche) en comparaison à une ration témoin sur les paramètres fécaux, la digestibilité des principaux nutriments et plusieurs paramètres biochimiques (glucose, insuline, azote alpha-aminé, urée, cholestérol et triglycérides) mesurés à jeun ou pendant six heures après le repas chez huit chiens adultes en bonne santé. Les régimes enrichis en pulpes ont entraîné une augmentation significative de l'excrétion fécale totale, de l'excrétion de MS dans les matières fécales, une diminution de la teneur en MS des fèces ainsi qu'une diminution des coefficients de digestibilité des principaux nutriments. Le régime contenant la pulpe de betterave a entraîné une diminution de la glycémie à jeun, de l'insulinémie et des concentrations en triglycérides postprandiales, des concentrations en urée et en cholestérol mesurées avant et après le repas. Le régime contenant la pulpe de chicorée a provoqué une diminution de l'insulinémie postprandiale, des concentrations en urée et en cholestérol à jeun et après le repas. Ces deux types de pulpes, semblables par leur composition, induisent les mêmes types d'effets sur les paramètres fécaux et la digestibilité des nutriments, mais les effets systémiques sont plus importants lors de la distribution de pulpes de betterave. [less ▲]

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See detailLa rhinotrachéite infectieuse bovine : caractéristiques du virus, l'infection et ses manifestations cliniques
Thiry, Etienne ULg; Lemaire, Mylène; Vanderheijden, Nathalie et al

in Bulletin des Groupements Techniques Vétérinaires (1997), 568

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See detailThe Color Purple - les Blues Pourpres d'Alice Walker
Sacré, Robert ULg

in Les Cahiers du Jazz (1997), 12

Un livre (1982) - un film ( Steven Spielberg, 1985)

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See detailAutour de Benjamin et Arendt
Delruelle, Edouard ULg

in Revue belge de Cinéma (1997), 41

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See detailFeeding of the sparid fish Sarpa salpa in a seagrass ecosystem: Diet and carbon flux
Havelange, S.; Lepoint, Gilles ULg; Dauby, Patrick ULg et al

in Marine Ecology (1997), 18(4), 289-297

In Revellata Bay (Gulf of Calvi, Corsica, France), the sparid fish Sarpa salpa L. is the main macro-consumer of Posidonia oceanica (L.) DELILE leaf. Stomach contents were analysed and C-13/C-12 isotopic ... [more ▼]

In Revellata Bay (Gulf of Calvi, Corsica, France), the sparid fish Sarpa salpa L. is the main macro-consumer of Posidonia oceanica (L.) DELILE leaf. Stomach contents were analysed and C-13/C-12 isotopic ratios were measured in fish muscle and potential food sources (algae, P. oceanica leaf and its epiphytes) to determine their relative contribution to the fish diet. S. salpa has an age-related mixed diet: juveniles are plankton feeders, young, sub-adults and adults are herbivorous, and, the older the individuals, the higher the relative contribution of P. oceanica to the diet. Our results and former studies of carbon stocks and fluxes in the P. oceanica bed of Revellata Bay have enabled an estimation of the general impact of S. salpa grazing on infralittoral communities: the studied species consumes 24 g C.m-2.a(-1) from P. oceanica leaf, 4.8 from epiphytes and 13 from epilithic algae. The fish net production and biomass turnover in that zone have been estimated to be 1.2 g C.m(-2).a(-1) and 1.5 a(-1), respectively. [less ▲]

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See detailIntensivemedizinische Probleme nach kardiochirurgischen Eingriffen in der Neugeborenenperiode
Hörnchen, H.; Dreuw, M.; Merz, U. et al

in Monatsschrift fur Kinderheilkunde (1997), 145

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See detailLe bois de tension. 2 Evaluation quantitative, formation et rôle dans l'arbre.
Jourez, Benoît ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(3), 167-177

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See detailFreeze-dried resorcinol-formaldehyde gels
Blacher, Silvia ULg; Pirard, René ULg; Pirard, Jean-Paul ULg et al

in Journal of Non-Crystalline Solids (1997), 212(2-3), 250-261

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer ... [more ▼]

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer to micrometer length-scale. Taking a standard freezing rate, we study in detail the influence of the molar ratio resorcinol/catalyst on the texture, This molar ratio is one of the parameters under consideration which can lead to a tailoring of the dried gel texture in order to develop adsorbents or catalyst supports of controlled porosity. Characterization methods include nitrogen adsorption-desorption (including the classical and the fractal interpretations), mercury porosimetry, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and small angle X-ray scattering (SAXS). [less ▲]

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See detailImprovement of inland navigation in developping countries: the training center of Palembang (Sumatra, Indonesia), an example of transfer of technology through education
Marchal, Jean ULg

in Bulletin des Séances de l’Académie Royale des Sciences d’Outre-Mer = Mededelingen der Zittingen van de Koninklijke Academie voor Overzeese Wetenschappen (1997), Nouvelle Série 42(4)(1er trimestre), 10

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See detailIUG-/ZOUG- dans une inscription latine écrite en lettres grecques (CIJ I 215)
Rochette, Bruno ULg

in Zeitschrift für Papyrologie und Epigraphik (1997), 115

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See detailEmergency Coronary Stenting with Wiktor Stent N Immediate and Late Results.
Bertrand, Olivier; Legrand, Victor ULg; Bilodeau et al

in The Journal of invasive cardiology (1997), 9(1), 2-9

In case of failed angioplasty, coronary stenting has gradually emerged as a non-surgical method to restore vessel patency and optimize coronary blood flow. There is still little clinical and angiographic ... [more ▼]

In case of failed angioplasty, coronary stenting has gradually emerged as a non-surgical method to restore vessel patency and optimize coronary blood flow. There is still little clinical and angiographic information on the use of radiopaque single loose interdigitating wire stents in angioplasty complicated by threatened or acute closure. Seventy-one patients received Wiktor stents after threatened vessel closure in 53 cases and acute closure in 18 cases. Stent delivery was successful in 98%. In-hospital death occurred in 1 case (1.4%). Stents occlusion were faced in 10 cases (14%), of which 6 presented early and 4 late after the procedure. Urgent bypass surgery was needed in 9 cases (12%) and 7 patients (10%) developed acute myocardial infarction. Serious bleeding complications occurred in 7 cases (10%) and vascular repair was performed in 4 patients (5%). During a follow-up of 20 +/- 10 months, 2 patients died, no myocardial infarction was observed and recurrence of angina was noted in 17 patients (24%). Angiographic analysis showed an acute gain in minimal lumen diameter of 1.71 +/- 0.22 mm and a late loss of 0.63 +/- 0.17 mm. Angiographic restenosis (diameter stenosis > 50%) presented in 20% of patients. Therefore, Wiktor stenting yields similar results than currently used stents in acute closure and strictly defined threatened vessel closure following angioplasty. [less ▲]

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See detailLe clonage par transfert de noyau dans l'espèce bovine
Ectors, Fabien ULg; Delval, Alain; Beckers, Jean-François ULg et al

in Annales de Médecine Vétérinaire (1997), 141

A all in vitro cloning technique was developed in wich embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer (re-cloning). Such method ... [more ▼]

A all in vitro cloning technique was developed in wich embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer (re-cloning). Such method permitted to produce 14,5% of morulae and 14,9% of blastocysts after the first and second cycle of nuclear transfer, respectively. The rates of birth obtained after transfer of such embryos were 21,4% and 20,5% for first and second cyle respectively, corresponding to 6 and 5 calves for 28 and 24 transferred embryos. Unfortunately, gestation patholgies and an increase of birth weights were observed. It seems that the in vitro presence of gametes and/or embryos may be responsible of an alteration in the control of gene expression. [less ▲]

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See detailFunctional anatomy of verbal and visuospatial span tasks in Alzheimer's disease
Collette, Fabienne ULg; Salmon, Eric ULg; Van der Linden, Martial ULg et al

in Human Brain Mapping (1997), 5(2), 110-118

The aim of the study was to emphasize cerebral regions which subserve the performance of short-term memory tasks in patients with Alzheimer's disease. We correlated scores obtained on span tasks with ... [more ▼]

The aim of the study was to emphasize cerebral regions which subserve the performance of short-term memory tasks in patients with Alzheimer's disease. We correlated scores obtained on span tasks with cerebral metabolism measured at rest with positron emission tomography. Scores obtained on the digit span task correlated with glucose metabolism in a brain area centered on the premotor cortex and extending to the adjacent motor and parietal gyri. There exists some evidence suggesting that this area may subserve the sequential organization of material stored in short-term memory. In a secondary analysis, we also observed significant interregional correlations between left-sided brain areas which are part of the neural network subserving verbal working memory processes in healthy controls. These data suggest that individual performance on verbal span tasks in AD patients may essentially depend on the preservation of their ordination processing capacity. The absence of correlation with prefrontal regions suggests that AD patients might not spontaneously engage central executive resources to reach their maximal span score. For simultaneous visuospatial span task, the performance of patients correlated with posterior brain regions, and not with prefrontal cortices. Hum. Brain Mapping 5:110-118, 1997. © 1997 Wiley-Liss Inc. [less ▲]

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See detailLa cartographie des hydrophytes appliquée à l'étude des écosystèmes fluviaux: un outil d'analyse pour la restauration des anciens chenaux rhénans
Klein, J. P.; Vanderpoorten, Alain ULg; Sanchez-Perez, J. et al

in Lejeunia, Revue de Botanique (1997), 153

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See detailOxydation photochimique de lixiviats de décharge
Deswaef, Sophie; Baidak, Alexandre; Crine, Michel ULg

in Tribune de l'Eau (La) (1997), 590-591

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See detailA 5,6-Dihydro-Isopyoverdin From Azomonas Macrocytogenes
Michalke, R.; Taraz, K.; Budzikiewicz, H. et al

in Zeitschrift Fur Naturforschung C-A Journal of Biosciences (1997), 52(11-12),

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See detailQtl Mapping to Qtl Cloning: Mice to the Rescue
Georges, Michel ULg

in Genome Research (1997), 7(7), 663-665

With the availability of dense, highly informative marker maps, it has recently become feasible to map genes (Quantitative Trait Loci or QTL) accounting for part of the heritability of continuously ... [more ▼]

With the availability of dense, highly informative marker maps, it has recently become feasible to map genes (Quantitative Trait Loci or QTL) accounting for part of the heritability of continuously distributed traits in experimental crosses as well as outbred populations. QTL mapping efforts have almost invariably revealed a limited number of loci with effects of a magnitude clearly departing from the predictions of the infinitesimal model (a model introduced to facilitate mathematical treatment of quantitative traits rather than to truly reflect their underlying biology). As most experimental designs would have limited detection power, which could lead to an overestimation of the identified gene effects, interpretation of results from QTL mapping studies must be viewed with caution. However, numerous independent confirmation studies leave little doubt that most quantitative traits indeed involve a limited suite of loci with major effect. This assertion seems to hold not only for QTL mapped in crosses between divergent lines, but—more importantly—for QTL segregating in outbred populations as well (for review, see Paterson 1995). Despite the sometimes unexpected magnitude of the identified QTL effects, the lack of simple correspondence between genotype and phenotype in complex trait analysis precludes the unambiguous identification of recombinant individuals. This may limit the achievable mapping resolution of QTL, posing a serious threat to the efficacy of positional (candidate) cloning for QTL considerably. QTL mapping efforts, whether performed in pedigrees or by exploiting linkage disequilibrium, are likely to leave geneticists with a portion of the genome that contains tens if not hundreds of genes and many DNA sequence polymorphisms to examine to identify the causal variant. Mutations causing monogenic inherited diseases are often destructive enough to leave little doubt about their causality. Even if the functional consequences of such mutations were less transparent, demonstration of a perfect correspondence between genotype and … [less ▲]

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See detailVrbis-Orbis (Ovide, Fastes, II, 684)
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (1997), 56(3), 551-553

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See detailEffect of bi-level positive airway pressure (BiPAP) nasal ventilation on the postoperative pulmonary restrictive syndrome in obese patients undergoing gastroplasty.
Joris, Jean ULg; Sottiaux, Thierry; Chiche, Jean-Daniel et al

in CHEST (1997), 111(3), 665-70

STUDY OBJECTIVE: Upper abdominal surgery results in a postoperative restrictive pulmonary syndrome. Bi-level positive airway pressure (BiPAP System; Respironics Inc; Murrysville, Pa), which combines ... [more ▼]

STUDY OBJECTIVE: Upper abdominal surgery results in a postoperative restrictive pulmonary syndrome. Bi-level positive airway pressure (BiPAP System; Respironics Inc; Murrysville, Pa), which combines pressure support ventilation and positive end-expiratory pressure via a nasal mask, could allow alveolar recruitment during inspiration and prevent expiratory alveolar collapse, and therefore limit the postoperative pulmonary restrictive syndrome. This study investigated the effect of BiPAP on postoperative pulmonary function in obese patients after gastroplasty. DESIGN: Prospective controlled randomized study. SETTING: GI surgical ward in a university hospital. PATIENTS: Thirty-three morbidly obese patients scheduled for gastroplasty were studied. INTERVENTION: The patients were assigned to one of three techniques of ventilatory support during the first 24 h postoperatively: O2 via a face mask, BiPAP System 8/4, with inspiratory and expiratory positive airway pressure set at 8 and 4 cm H2O, respectively, or BiPAP System 12/4 set at 12 and 4 cm H2O. Pulmonary function (FVC, FEV1, and peak expiratory flow rate [PEFR]) were measured the day before surgery, 24 h after surgery, and on days 2 and 3. Oxygen saturation by pulse oximeter (SpO2) was also recorded during room air breathing. RESULTS: Three patients were excluded. After surgery, FVC, FEV1, PEFR, and SpO2 significantly decreased in the three groups. On day 1, FVC and FEV1 were significantly improved in the group BiPAP System 12/4, as compared with no BiPAP; SpO2 was also significantly improved. After removal of BiPAP System 12/4, these benefits were maintained, allowing faster recovery of pulmonary function. No significant effects were observed on PEFR. BiPAP System 8/4 had no significant effect on the postoperative pulmonary restrictive syndrome. CONCLUSION: Prophylactic use of BiPAP System 12/4 during the first 24 h postoperatively significantly reduces pulmonary dysfunction after gastroplasty in obese patients and accelerates reestablishment of preoperative pulmonary function. [less ▲]

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See detailRhômé = rhômé
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (1997), 56(1), 54-57

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See detailVerapamil, a phenylalkylamine Ca2+ channel blocker, inhibits ATP-sensitive K+ channels in insulin-secreting cells
Lebrun, P.; Antoine, M.-H.; Ouedraogo, R. et al

in Diabetologia (1997), 40

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See detailCharacterization of Clostridium perfringens isolated from necrotic enteritis of fowls.
Das, B. C.; Dutta, G. N.; Daube, Georges ULg et al

in Indian Journal of Animal Sciences (The) (1997), 67

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See detailAnaesthesia for thoracoscopic surgery
Larbuisson, Robert ULg; Lamy, Maurice ULg

in Current Opinion in Anaesthesiology (1997), 10

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See detail"De l'Olympe au réseau..." Comment les philologues classiques allemands font face aux réalités contemporaines
Rochette, Bruno ULg

in Bulletin de la Fédération des Professeurs de Grec et de Latin (1997), 108(septembre-octobre), 6-7

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See detailLes strychnos africains et leurs alcaloïdes
Delaude, Clément ULg; Delaude, Lionel ULg

in Bulletin de la Société Royale des Sciences de Liège (1997), 66(4), 183-286

In the Greek Antiquity, the term strychnos was first coined to describe various toxic Solanacae. Nowadays, the genus Strychnos created by Linnaeus in 1753 is the numerically most important genus from the ... [more ▼]

In the Greek Antiquity, the term strychnos was first coined to describe various toxic Solanacae. Nowadays, the genus Strychnos created by Linnaeus in 1753 is the numerically most important genus from the Loganiaceae family and comprises 196 species growing in the warm regions of Asia (58 species), America (64) and Africa (75). Species on the three continents are almost totally segregated. Only Strychnos potatorum is common to Asia and Africa. The toxicity of Strychnos was empirically well-known from time immemorial. Inhabitants of South-Eastern Asia and India had an ancestral knowledge of Strychnos nux vomica, whose deadly poisonous seeds were later imported and marketed in Europe to kill rodents and small predators. Concentrated extracts from Amazonian Strychnos, known as curares, are also remarkable hunting poisons, used by South American Indians. Accordingly, modern scientific investigations of Strychnos and their alkaloids started with Asian or American species used as traditionnal poisons. Strychnine was the first alkaloid found in Strychnos. It was isolated from Asian S. nux vomica in 1818, but its structure was fully elucidated only in the 1950s. Meanwhile, various curarizing alkaloids from American Strychnos were identified. Based on these early results, Strychnos alkaloids were initially classified according to their geographical origin. Asian Strychnos were assumed to contain strychnine and related compounds, whereas curarizing ammonium salts were associated with American Strychnos. African species were assimilated to their Asian counterparts and deemed of less interest. During the last three decades, however, systematic screening of African Strychnos has revealed the presence of numerous, varied alkaloids in these plants and demonstrated that the correlation between geographical distribution and alkaloid content was erroneous. Presently, 47 African species have been investigated and their alkaloids analyzed, significantly more than Asian and American materials (about 10 and 20 species, respectively). In this review, we present the alkaloids isolated so far from African Strychnos. 309 structures are listed and sorted according to their molecular weight, the most useful index key in modern research based on mass spectrometry. [less ▲]

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See detailSynthesis and biological evaluation of sulfonylcyanoguanidines and sulfonamidonitroethylenes as bioisosteres of hypoglycemic sulfonylureas
Masereel, B.; Ouedraogo, R.; Dogne, J.-M. et al

in European Journal of Medicinal Chemistry (1997), 32

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See detailRoom temperature fluorescence spectra of protochlorophyllide and chlorophyllide forms in etiolated bean leaves
Boddi, B.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (1997), 41(1-2), 73-82

Room-temperature fluorescence emission and excitation spectra of 3-day or 10-day old dark-grown bean (Phaseolus vulgaris L. cv Commodore) leaves were measured. The excitation light was defocused in such ... [more ▼]

Room-temperature fluorescence emission and excitation spectra of 3-day or 10-day old dark-grown bean (Phaseolus vulgaris L. cv Commodore) leaves were measured. The excitation light was defocused in such way that only a low rate of phototransformation took place and protochlorophyllide (Pchlide) forms could be detected. The spectra were resolved into gaussian components using a new method based on the comparison of the 4th derivative of the experimental spectrum and that of the calculated spectrum, i.e. the sum of the gaussians. In addition to Pchlide emission bands with maxima at 631, 644, 655 and 667 nm which correspond to those described earlier in 77 K spectra, two new and unusally narrow bands were found at 637 and 650 nm. Tn the Chlide region, emission bands were found at 676, 682, 686 and 695 nm. Changes in the relative amplitudes of the Pchlide and Chlide room temperature emission bands as a function of age, of excitation wavelength and in response to a short light flash were studied. A model is given in which dynamic interconversions of the pigment forms are suggested and the presence of the new forms is explained with the differences in the aggregational states of the pigments and with their interaction with NADPH or NADP(+). (C) 1997 Elsevier Science S.A. [less ▲]

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See detailPhénomènes karstiques dans les roches plutoniques et métamorphiques du sud Cameroun
Vicat, Jean-Paul; Lips, Bernard; Pouclet, André et al

in Karstologia (1997), 29

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See detailMonotonous stability for neutral fixed points
Bair, Jacques ULg; Haesbroeck, Gentiane ULg

in Bulletin of the Belgian Mathematical Society Simon Stevin (1997), 4(5), 639-646

We give subtle, simple and precise results about the convergence or the divergence of the sequence (x(n)), where x(j) = f(x(j-1)) for every integer j, when the initial element x(0) is in the neighbourhood ... [more ▼]

We give subtle, simple and precise results about the convergence or the divergence of the sequence (x(n)), where x(j) = f(x(j-1)) for every integer j, when the initial element x(0) is in the neighbourhood of a neutral fixed point, i.e. a point x* such that f(x*) = x* with \f'(x*)\ = 1 (where f is a C-infinity function defined on a subset of R). [less ▲]

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See detailRyle et la phénoménologie
Leclercq, Bruno ULg

in Recherches Husserliennes (1997), 7

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See detailApparition tardive d'une infertilité masculine
Geenen, Vincent ULg; PERRIER d'HAUTERIVE, Sophie ULg

in Actualité Médicale Belge (1997), 565

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See detailGravitational lensing by damped Ly-alpha absorbers
Smette, Alain; Claeskens, Jean-François ULg; Surdej, Jean ULg

in New Astronomy (1997), 2

Assuming that (i) damped Ly-alpha absorbers (DLAs) arise in present-day-like spiral galaxies which are immersed in isothermal dark matter halos, (ii) that these galaxies obey the Tully-Fisher sigma/sigma ... [more ▼]

Assuming that (i) damped Ly-alpha absorbers (DLAs) arise in present-day-like spiral galaxies which are immersed in isothermal dark matter halos, (ii) that these galaxies obey the Tully-Fisher sigma/sigma_* = (L/L_*)^1/alpha_TF and the Holmberg R_L/R_* = (L/L_*)^alpha_H relations, and (iii) that they follow the Schechter luminosity distribution, we describe how their observed number density (dN/dz), distribution of column density (f(N)) as well as inferred cosmological density of HI (Omega_HI) derived from DLA surveys are affected by gravitational lensing (GL). The `by-pass' effect causes the lines-of-sight (LOSs) towards background QSOs to avoid the central parts of galaxies and reduces their effective cross-section for absorption; the `amplification bias' leads observers to select QSOs whose LOSs preferentially cross galaxies close to their Einstein radius. As a consequence, the determination of the quantities dN/dz, f(N) and Omega_HI from DLA surveys does not only depend on the redshift z and luminosity L of galaxies responsible for the absorbers but also on the column density profile of HI within the galaxies and on the redshift z_q and magnitude b_q of the background QSOs. For most of the existing surveys using b_q <~ 19 QSOs, the amplification bias dominates the combined effect resulting in a slight overestimate of dN/dz, f(N) and Omega_HI. We mainly find that observational strategies presently used to produce high-z DLA surveys result in avoiding the signature of significant GL effects: following our model, we determine that an overestimate of Omega_HI by more than 10% is unlikely for the z > 1.7 existing surveys, but may reach ~= 35% for the low redshift ones. However, we show that, in the absence of extinction by dust and micro-lensing effects, surveys ideally designed to enhance GL effects, i.e. to search for DLAs at z ~ 0.5 in front of very bright (b_q ~= 16), high-z (z_q > 1) QSOs, may lead 1) to overestimate by up to ~= 90% the number of DLAs per unit redshift; 2) to bias the survey towards high HI column density systems so that it could contain up to 4 times as many such systems, thus 3) to overestimate by up to ~= 170% the cosmological density of gas associated with those DLAs. Identification of the galaxies responsible for the DLAs may be severely biased towards luminous galaxies if 2/alpha_TF - alpha_H>0 this latter effect is greatly increased for log N_HI > 21 DLAs. Hence, GL effects on the quantities derived from surveys for z ~ 0.5 DLAs are of the same order, but of opposite direction, as the effects of extinction by dust (cf. Fall & Pei, 1993). However, the GL and dust extinction effects do not compensate each other: combining them in a consistent way is necessary to interpret existing DLA surveys. Furthermore, the effects due to micro-lensing should be simultaneously taken into account. We intend to report the results on the complex interplay between macro-lensing, micro-lensing and dust in a subsequent paper. We briefly present statistical tests specifically designed to check whether GL affects existing DLA surveys, and assuming that extinction by dust is negligible. We only find indications of GL effects for the z < 1 ones which, if confirmed, might even be stronger than predicted by our model. We show that an independent work on the same subject by Bartelmann & Loeb (1996) incorrectly treats the inclination effects for the intervening galaxies, thus undermining some of their main results and conclusions. [less ▲]

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See detailLa prééclampsie est la conséquence d'un déficit de placentation: de la biologie aux considérations cliniques
Maquoi, Erik ULg; Schaaps, Jean-Pierre ULg; Jacobs, J. L. et al

in Revue Médicale de Liège (1997), 52(7), 478-84

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See detailThe veno-occlusive disease of the liver.
Baron, Frédéric ULg; Deprez, Manuel ULg; Beguin, Yves ULg

in Haematologica (1997), 82(6), 718-25

BACKGROUND AND OBJECTIVE: The veno-occlusive disease of the liver (VOD) is a disorder caused by the non-thrombotic occlusion of the central veins of hepatic lobules. The clinical features are similar to ... [more ▼]

BACKGROUND AND OBJECTIVE: The veno-occlusive disease of the liver (VOD) is a disorder caused by the non-thrombotic occlusion of the central veins of hepatic lobules. The clinical features are similar to those of intrahepatic portal hypertension (unexplained weight gain, ascites, painful hepatomegaly, jaundice). In the past, this disease was rather infrequent and was linked to the absorption of toxic agents, liver irradiation or chemotherapy. However, the intensification of treatment protocols before hematopoietic stem cell transplants has considerably increased its incidence. The strategies used for its prevention and treatment remain limited in efficacy. The present review was undertaken in order to assess progress in the diagnosis and management of this severe complication in stem cell transplantation. INFORMATION SOURCES: The method used for preparing this review was an examination of 250 relevant articles or abstracts published in journals covered by Medline. STATE OF ART: Despite the progress made toward the understanding of its physiopathology and the identification of its risk factors, VOD is still one of the leading causes of morbidity and mortality during the first two months post-BMT, and therefore often constitutes a limitation for the further increment of the dose of antineoplastic drugs. This may be explained by the difficulty in making an early diagnosis of this problem, at a time when therapeutic intervention may be more effective, and, on the other hand, the lack of a well-established prevention and treatment approach for patients with VOD. PERSPECTIVES AND CONCLUSIONS: New diagnostic procedures, such as laparoscopic liver biopsy, and new therapeutic approaches, such as transjugular intrahepatic portosystemic shunting (TIPS) or defibrotide, are now being evaluated. However, additional studies will be needed to determine the most appropriate therapy for each VOD patient depending on the severity of the disease. [less ▲]

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See detailTowards interbreed IBD fine mapping of the mh locus: double-muscling in the Asturiana de los Valles breed involves the same locus as in the Belgian Blue cattle breed.
Dunner, S.; Charlier, Carole ULg; Farnir, Frédéric ULg et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (1997), 8(6), 430-5

The Spanish "Asturiana" cattle breed is characterized by the segregation of a genetically determined muscular hypertrophy referred to as double-muscling or "culones". We demonstrate by linkage analysis ... [more ▼]

The Spanish "Asturiana" cattle breed is characterized by the segregation of a genetically determined muscular hypertrophy referred to as double-muscling or "culones". We demonstrate by linkage analysis that this muscular hypertrophy involves the mh locus previously shown to cause double-muscling in the Belgian Blue cattle breed, pointing towards locus homogeneity of this trait across both breeds. Moreover, using a twopoint and multipoint maximum likelihood approach, we show that flanking microsatellite markers are in linkage disequilibrium with the mh locus in both breeds albeit with different alleles. Finally, we discuss how allelic homogeneity across breeds might be exploited to achieve efficient genetic fine-mapping of the mh locus. [less ▲]

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See detailFreeze-drying of lactic acid bacteria : Lactobacillus acidophilus
Desmons, S.; Zgoulli, S.; Destain, Jacqueline ULg et al

in Mededelingen - Faculteit Landbouwwetenschappen, Rijksuniversiteit Gent (1997), 62/4b

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See detailThe glucocorticoid receptor inhibits the human prolactin gene expression by interference with Pit-1 activity
Nalda, Asunción M; Martial, Joseph ULg; Muller, Marc ULg

in Molecular & Cellular Endocrinology (1997), 134(2), 129-37

Glucocorticoids have been shown to inhibit the activity of the human prolactin (hPRL) promoter. Using transient expression experiments in rat pituitary cells, we located the sequence conferring ... [more ▼]

Glucocorticoids have been shown to inhibit the activity of the human prolactin (hPRL) promoter. Using transient expression experiments in rat pituitary cells, we located the sequence conferring glucocorticoid inhibition to a region which contains Pit-1 binding sites, responsible for pituitary-specific expression, but does not seem to contain a glucocorticoid receptor (GR) binding site. Co-transfection experiments in non-pituitary cell lines, using expression vectors for Pit-1 and different mutants of the human GR show that inhibition of the hPRL gene is seen only in the presence of Pit-1 and GR, and that the DNA binding function of the receptor is not required. Immunoprecipitation studies show that either anti-GR or anti-Pit-1 antibodies are able to co-precipitate GR and Pit-1, suggesting an interaction between these factors. We conclude that the activated GR functionally interferes with the pituitary specific factor Pit-1, thereby leading to the observed transcriptional repression. [less ▲]

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See detailGrecs, Romains et Barbares. A la recherche de l'identité ethnique et linguistique des Grecs et des Romains
Rochette, Bruno ULg

in Revue Belge de Philologie et d'Histoire (1997), 75

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See detailL'hypoglycemie du patient diabetique. Recommendations of ALFEDIAM (French Language Association for the Study of Diabetes and Metabolic Diseases.
Grimaldi, A.; Slama, G.; Tubiana-Rufi, N. et al

in Diabètes & Métabolism (1997), 23(1), 100-8

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See detailFormation of long-wavelength chlorophyllide (Chlide695) is required for the assembly of Photosystem II in etiolated barley leaves
Franck, Fabrice ULg; Eullaffroy, P.; Popovic, R.

in Photosynthesis Research (1997), 51(2), 107-118

Chlorophyll(ide) spectroscopic properties and Photosystem II assembly, monitored by 77 K variable fluorescence, were studied in etiolated barley leaves as a function of the extent of protochlorophyllide ... [more ▼]

Chlorophyll(ide) spectroscopic properties and Photosystem II assembly, monitored by 77 K variable fluorescence, were studied in etiolated barley leaves as a function of the extent of protochlorophyllide photoreduction by a single millisecond light flash of different intensities. Variable fluorescence, measured 2 hours after the flash, was only detected when the extent of phototransformation was higher than a threshold value of 0.4. Its development paralleled the formation of a chlorophyll emission component at 685 nm, which itself derived from long-wavelength chlorophyllide with an emission maximum at 695 nm. At low flash intensities, short-wavelength chlorophyllide forms preferentially accumulated and no Photosystem II fluorescence was detected after 2 hours. Chlorophyllide esterification was independent of the extent of phototransformation. These results suggested that the formation of long-wavelength chlorophyllide was essential for further assembly of Photosystem II. This interpretation was strengthened by the observed inhibition of both long-wavelength chlorophyllide formation and of variable fluorescence development in leaves treated with 6-aminolevulinic acid or in untreated leaves subjected to repeated flashes of low intensity. [less ▲]

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See detail67-kD laminin receptor expression correlates with worse prognostic indicators in non-small cell lung carcinomas.
Fontanini, G.; Vignati, S.; Chine, S. et al

in Clinical Cancer Research : An Official Journal of the American Association for Cancer Research (1997), 3(2), 227-31

Tumor samples obtained from 72 patients resected for non-small cell lung cancer were stained immunohistochemically using an immunoperoxidase method and the MLuC5 monoclonal antibody specific for the 67 ... [more ▼]

Tumor samples obtained from 72 patients resected for non-small cell lung cancer were stained immunohistochemically using an immunoperoxidase method and the MLuC5 monoclonal antibody specific for the 67-kDa laminin receptor. Sixty-one of 72 patients (84.7%) displayed a MLuC5-positive reaction, which was usually localized in both the inner surface of the plasmatic membranes and the cytoplasm of neoplastic cells. When we compared the laminin receptor expression with clinicopathological and biological parameters such as histotype, grading, T status, N status, ploidy, proliferative activity, vessel invasion, and p53 protein accumulation, the following results were observed: (a) the mean expression of the receptor was higher in the group of patients with metastatic nodal involvement than in those with uninvolved lymph nodes (P = 0.02); (b) a high Ki-67 score (>13% of positive cells) was observed in tumors with a higher mean value of laminin receptor (P = 0.004); (c) the tumors harboring neoplastic emboli in their vessels showed a higher laminin receptor immunoreactivity (P = 0.02); and (d) a borderline association was found between the high mean value of laminin receptor immunopositivity and p53 accumulation in neoplastic cell nuclei (P = 0.05). Our observations indicate that detection of high tissue levels of 67-kDa laminin receptor is associated with an invasive phenotype in non-small cell lung cancer and may provide further information in the biological characterization of this type of cancer. [less ▲]

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See detailOccult genital herpes presenting as an endometrial infection detected at delivery: a report of two cases
Aghazarian, Saro; Nikkels, Arjen ULg; Grodos, Jacques et al

in Journal of the European Academy of Dermatology & Venereology (1997), 9

Background: The prevalence and clinical implications of asymptomatic genital herpes remain elusive. Objective/aim: We report two cases of clinically asymptomatic intrautcrine herpes simplex virus II (HSV ... [more ▼]

Background: The prevalence and clinical implications of asymptomatic genital herpes remain elusive. Objective/aim: We report two cases of clinically asymptomatic intrautcrine herpes simplex virus II (HSV-II) infection in order to discuss their pathological significance and demonstrate the potential utility of specific DNA probes and antibodies. Methods: Standard histology, immunohistochemistry (IHC) and in situ hybridization (ISH) were applied to formalin-tixed. paraffin-em bedded lissue sections of curettage specimens from women presenting deciditalised fragments retention after normal delivery. Results: Hisiological analysis revealed a focal clearing of endometrial epithelial cell nuclei, suggesting a viral etiology. ISH and IHC with differetit DNA probes or antibodies confirmed the diagnosis of HSV-II infection at the time of specimen collection. Clinical signs of muco-cutaneous involvement in the mothers and of neonatal HSV infection were not observed. Conclusion: These findings suggest that intrauterinc HSV-II infection is not always associated with disease. The IHC and ISH methods can be helpful to a.ssess the diagnosis of HSV-II intrauterine infections in the presence of optically clear cndotTietrial nuclei. Whether or not such HSV-II occult infection may be associated with viral shedding and risk of sexual transtnission was not evaluated in the present study. © 1997 Elsevier Science B.V. [less ▲]

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See detailUse of anti inflammatory drugs in the treatment of bovine respiratory disease complex
Lekeux, Pierre ULg; VandeWeerdt, M. L.

in Israel Journal of Veterinary Medicine (1997), 52(2-3), 113-116

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See detailAirborne dust and aeroallergen concentrations in different sources of feed and bedding for horses
Vandenput, Sandrina ULg; Istasse, Louis ULg; Nicks, Baudouin ULg et al

in Veterinary Quarterly (The) (1997), 19(4), 154-158

Standardized methods were used to make quantitative and qualitative assessments of respirable dust and aeroallergens in feed and bedding for horses. Concentrations of airborne dust were measured by using ... [more ▼]

Standardized methods were used to make quantitative and qualitative assessments of respirable dust and aeroallergens in feed and bedding for horses. Concentrations of airborne dust were measured by using a Rion particle counter, and levels of major aeroallergens implicated in chronic obstructive pulmonary disease were measured by using an Andersen sampler. Laboratory conditions allowed comparison of the different sources of forage, supplements, and bedding without external influences such as ventilation, external temperature and horse activity affecting the result. Grass silages of approximately 50% dry matter and alfalfa pellets appeared to be very good sources of forage with low levels of dust and aeroallergens. The studied good quality straw was significantly less dusty with fewer allergens than the wood shavings. Supplements, such as whole grains and molassed concentrates, contained many respirable particles and aeroallergens. Rolled grains were significantly more dusty than good hay. [less ▲]

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See detailFibres alimentaires chez le chien : VII. Intérêt dans le traitement diététique de l'animal obèse
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with ... [more ▼]

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with particular emphasis on the incorporation of large quantities of dietary fibres in low-energy specific purpose food. At present time, no conclusions can be drawn from published studies [less ▲]

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See detailIdentification des vaches laitières traitées à la somatotropine bovine
Scippo, Marie-Louise ULg; Degand, Guy ULg; Duyckaerts, Anne et al

in Annales de Médecine Vétérinaire (1997), 141(5), 381-390

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See detailProcesses in regions of freshwater influence (ROFI)
Nihoul, Jacques ULg; Djenidi, Salim ULg; Huthnance, J. M. et al

in Journal of Marine Systems (1997), 12(1-4), 1-2

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See detailQuelle est la place de l’Université dans notre société ?
Brunet, Sébastien ULg

in Revue l’Observatoire (1997), 15

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See detailThe Cloning And Sequencing Of An Ovine C-Myc Cdna
Kiermer, V.; Dequiedt, Franck ULg; Masengo, R. et al

in DNA Sequence : The Journal of DNA Sequencing & Mapping (1997), 7(3-4),

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See detailBiomarqueurs et bioindicateurs chez les vertébrés : importance pour l’évaluation de la santé d’un écosystème
Lessire, Françoise ULg; Delaunois, Annie; Gustin, Pascal ULg et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailLa torsion isolée de la rate : cas clinique et revue de la littérature
Zonderland, J. L.; Balligand, Marc ULg; Snaps, Frédéric ULg et al

in Annales de Médecine Vétérinaire (1997), 141

This paper describes a case report and reviews the literature concerning isolated torsion of the splenic pedicle in a dog. Splenic torsion is found in young, large and deep-chested dogs with a prevalence ... [more ▼]

This paper describes a case report and reviews the literature concerning isolated torsion of the splenic pedicle in a dog. Splenic torsion is found in young, large and deep-chested dogs with a prevalence of 3.5 to 6%. The pathogenesis of isolated splenic torsion is unknown, Clinical signs and diagnostic procedures are non specific. Only sonographic changes are valuable in performing an etiologic diagnosis, The surgical treatment consists in a splenectomy, An early diagnosis and surgical treatment usually lead to a good prognosis. [less ▲]

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See detailMolecular dissection of the insulin-like growth factor axis in the human thymus
Geenen, Vincent ULg; Kecha, Ouafae; Achour, Imane et al

in Diabetologia (1997), 40

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See detailMultipole Transitions in Nicke-like and Palladium-like Spectra
Biémont, Emile ULg

in Journal of Physics : B Atomic Molecular & Optical Physics (1997), 30

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See detailMéthodes chromatographiques de dosage dans les milieux biologiques : stratégie de validation - Rapport d'une commission SFSTP
Chapuzet, E.; Mercier, N.; Bervoas-Martin, S. et al

in STP Pharma Pratiques (1997), 7(3), 169-194

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See detailLes protéases stromales dans la progression cancéreuse mammaire
Foidart, Jean-Michel ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1997), 152(5), 229-35235-7

Matrix metalloproteases represent a family of proteases secreted as latent inactive enzymes able to degrade the majority of extracellular matrix components. These enzymes are overexpressed during several ... [more ▼]

Matrix metalloproteases represent a family of proteases secreted as latent inactive enzymes able to degrade the majority of extracellular matrix components. These enzymes are overexpressed during several pathological tissue remodelings including tumor progression and tumor invasion. It was indeed classically admitted that matrix metalloproteases involved in tumoral progression were preferentially expressed by cancerous cells. Our studies on gelatinase A and stromelysin-3 have, however, demonstrated that their messenger RNAS are detected in fibroblasts of the peritumoral stroma in human mammary carcinoma and not in the cancerous cells themselves. By immunohistochemistry, we have detected gelatinase A in the cytoplasm of fibroblasts and at the surface of the tumor cells. This membrane localization of the protein could result from its binding, following secretion by the neighbouring stromal cells, to a specific binding site expressed at the surface of the carcinoma cells. These cells are indeed able to induce an increased proteolytic activity by enhancing the transcription of these enzymes by peritumoral fibroblasts. These enzymes represent therefore potential targets for the development of new therapeutic strategies. [less ▲]

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See detailPhosphorylation of the Bovine Leukemia Virus transactivator p34Tax is required for transformation but not for transactivation.
Kettmann, Richard ULg; Grimonpont, C.; Kerkhofs, Pierre et al

in FASEB Journal (1997), 11(9), 1179

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See detailStability margins of nonlinear receding horizon control via inverse optimality
Magni, L.; Sepulchre, Rodolphe ULg

in Systems & Control Letters (1997), 32(4), 241-245

Using the nonlinear analog of the Fake Riccati equation developed for linear systems, we derive an inverse optimality result for several receding horizon control schemes. This inverse optimality result ... [more ▼]

Using the nonlinear analog of the Fake Riccati equation developed for linear systems, we derive an inverse optimality result for several receding horizon control schemes. This inverse optimality result unifies stability proofs and shows that receding horizon control possesses the stability margins of optimal control laws. [less ▲]

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See detailSoil Solution Nitrogen and Cations Influenced by (NH4)2SO4 Deposition in a Coniferous Forest
Carnol, Monique ULg; Ineson, Phil; Dickinson, A. L.

in Environmental Pollution (1997), 97(1-2), 1-10

The effects of chronically enhanced (NH(4))(2)SO(4) deposition on ion concentrations in soil solution and ionic fluxes were investigated in a Picea abies plot at Grizedale forest, NW England. Soil cores ... [more ▼]

The effects of chronically enhanced (NH(4))(2)SO(4) deposition on ion concentrations in soil solution and ionic fluxes were investigated in a Picea abies plot at Grizedale forest, NW England. Soil cores closed at the base and containing a ceramic suction cup sampler were 'roofed' and watered every 2 weeks with bulk throughfall collected in the field. Treatments consisted of the inclusion of living roots from mature trees in the lysimeters and increasing (NH(4))(2)SO(4) deposition (NS treatment) to ambient + 75 kg N ha(-1) a(-1). Rainfall, throughfall and soil solutions were collected every 2 weeks during 18 months, and analysed for major cations and anions. NO(3)(-) fluxes significantly increased following NS treatment, and were balanced by increased Al(3+) losses. Increased SO(4)(2-) concentrations played a minor role in controlling soil solution cation concentrations. The soil exchange complex was dominated by Al and, during the experimental period, cores of all treatments 'switched' from Ca(2+) to Al(3+) leaching, leading to mean [Formula: see text] molar ratios in soil solution of NS treated cores of 0.24. The experiment confirmed that the most sensitive soils to acidification (through deposition or changing environmental conditions) are those with low base saturation, and with a pH in the lower Ca, or Al buffer ranges. [less ▲]

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See detailLes antidotes en Médecine Vétérinaire
Delaunois, A.; Plume, Ch; Ansay, M. et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailThe He(I), Threshold photoelectron and Constant Ion State spectroscopy of Vinylchloride (C2H3Cl).
Locht, Robert ULg; Leyh, Bernard ULg; Hottmann, K. et al

in Chemical Physics (1997), 220

Using synchrotron radiation the threshold photoelectron (TPES) spectrum and constant ion state (CIS) spectroscopy of C2H3Cl are reported. For comparison, the He(I) photoelectron spectrum has also been ... [more ▼]

Using synchrotron radiation the threshold photoelectron (TPES) spectrum and constant ion state (CIS) spectroscopy of C2H3Cl are reported. For comparison, the He(I) photoelectron spectrum has also been measured and reexamined. The threshold photoelectron spectrum has been measured between 9.0 and 25.0 eV and the photon energy range of 9.9-12.0 eV has been investigated in detail. Many features have been identified and tentatively assigned with the help of the photoabsorption spectroscopic results. These data were compared with the well-resolved He(I) photoelectron spectrum. The fine structure observed in the two first ionic states is assigned to progressions belonging partially to previously unobserved vibration normal modes. State-selected CIS spectra have been recorded for the first vibronic states between 10.0 and 11.67 eV. They exhibit fine structure assigned to autoionization of Rydberg states. [less ▲]

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See detailAspects of the Upper Palaeolithic in Central Europe
Otte, Marcel ULg; Noiret, Pierre ULg; López Bayón, Ignacio

in Préhistoire Européenne (1997), 11

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See detailPrognostic factors in urothelial renal pelvis and ureter tumors: A multicenter Rare Cancer Network study
Ozsahin, Mahmut; Zouhair, Abderrahim; Villà, S. et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 3(2(supp)), 290

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See detailContribution à l'étude de la flore et de l'écologie des plantes de quelques grottes wallonnes.
Garbacki, Nancy ULg

in Bulletin des Chercheurs de la Wallonie (1997), XXXVI

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See detailEvidence for a Non-Gabaergic Action of Quaternary Salts of Bicuculline on Dopaminergic Neurones
Seutin, Vincent ULg; Scuvée-Moreau, Jacqueline ULg; Dresse, Albert ULg

in Neuropharmacology (1997), 36(11-12, Nov-Dec), 1653-7

Intracellular recordings were made from neurones, presumed to be dopaminergic, in the rat midbrain slice preparation. Bicuculline methiodide (BMI) and methochloride (BMC) reversibly blocked the slow ... [more ▼]

Intracellular recordings were made from neurones, presumed to be dopaminergic, in the rat midbrain slice preparation. Bicuculline methiodide (BMI) and methochloride (BMC) reversibly blocked the slow, apamin-sensitive component of the afterhyperpolarization in these cells. The IC50 for this effect was about 26 microM. In comparison, BMC antagonized the input resistance decrease evoked by muscimol (3 microM) with an IC50 of 7 microM. The base of bicuculline was less potent in blocking the slow afterhyperpolarization. SR95531 (2-[carboxy-3'-propyl]-3-amino-6-paramethoxy-phenyl-pyridaziniu m bromide), another competitive GABA(A) antagonist, and picrotoxin, a non-competitive GABA(A) antagonist, also blocked the action of muscimol (IC50s: 2 and 12 microM respectively), but had no effect on the afterhyperpolarization at a concentration of up to 100 microM. Moreover, 100 microM SR95531 did not affect the blockade of the afterhyperpolarization by BMC. This blockade persisted in the presence of tetrodotoxin and was apparently not due to a reduction of calcium entry, suggesting that it involved a direct action on the channels which mediate this afterhyperpolarization. These results strongly suggest that quaternary salts of bicuculline act on more than one target in the central nervous system. Thus, the involvement of GABA(A) receptors in a given effect cannot be proven solely on the basis of its blockade by these agents. [less ▲]

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See detailOrigine sociale et réussite scolaire : un modèle en Chaîne de Markov estimé sur données individuelles belges
Donni, Olivier; Lejeune, Bernard ULg

in Recherches Economiques de Louvain (1997), 63(4), 421-446

Cet article étudie les relations entre l'origine socio-économique des élèves belges et leur parcours scolaire primaire et secondaire. Il repose sur l'hypothèse que le parcours scolaire des élèves peut ... [more ▼]

Cet article étudie les relations entre l'origine socio-économique des élèves belges et leur parcours scolaire primaire et secondaire. Il repose sur l'hypothèse que le parcours scolaire des élèves peut être décrit par un processus de Markov. Sur la base d'un échantillon transversal d'un millier d'enfants, en fonction de variables socio-économiques et pour chacune des années de scolarité obligatoire, les probabilités individuelles de poursuivre un parcours scolaire ''normal'', c.-à-d. sans redoublement ni relégation dans une filière de second choix, sont estimées. Nos résultats montrent que derrière les substantiels taux agrégés de redoublement qui caractérisent le système scolaire belge se cachent en fait de profondes inégalités sociales. [less ▲]

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See detailThe Nucleotide Sequence Of Saccharomyces Cerevisiae Chromosome XII
Johnston, M.; Hillier, L.; Riles, L. et al

in Nature (1997), 387(6632),

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See detailVers une chirurgie mammaire supraconservatrice des lésions mammaires infracliniques?
LIFRANGE, Eric ULg; COLIN, Claude

in Gunaïkeia (1997), 2

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See detailA primal-dual approach in truss topology optimization
Beekers, M.; Fleury, Claude ULg

in Computers & Structures (1997), 64(1-4), 77-88

The objective of truss topology optimization is to find, for a given weight, the stiffest truss, defined as a subset of an initially choosen set of bars called the ground structure. The restrictions are ... [more ▼]

The objective of truss topology optimization is to find, for a given weight, the stiffest truss, defined as a subset of an initially choosen set of bars called the ground structure. The restrictions are bounds on bar volumes and the satisfaction of equilibrium equations. For a single load case and without bounds on bar volumes, the problem can be written as a linear programming problem with nodal displacements as variables. The addition to the objective function of a quadratic term vanishing at the optimum allows us to use a dual solution scheme. A conjugate gradient method is well suited to maximize the dual function. Several ground structures are introduced. For large networks, those where each node is connected to those situated in a certain vicinity give a good compromise between generating a reasonable number of bars and obtaining a sufficient number of possible directions. Some examples taken from the literature are treated to illustrate the quality of the solution and the influence of initial topology. (C) 1997 Civil-Comp Ltd and Elsevier Science Ltd. [less ▲]

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See detailLes rideaux de Magritte
Steinmetz, Rudy ULg

in Degrés : Revue de Synthèses à Orientation Sémiologique (1997)

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See detailA 12 Kb Nucleotide Sequence Containing The Alanine Dehydrogenase Gene At 279 Degrees On The Bacillus Subtilis Chromosome
Oudega, B.; Vandenbol, Micheline ULg; Koningstein, G.

in Microbiology-Uk (1997), 143

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See detailSynthesis and characterization of monodisperse spherical zirconia particles
Van Cantfort, Olivier; Michaux, Bernard; Pirard, René ULg et al

in Journal of Sol-Gel Science and Technology (1997), 8

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See detailIn vivo behavior of poly(D,L)-lactide microspheres designed for chemoembolization
Flandroy, P.; Grandfils, Christian ULg; Danen, B. et al

in Journal of Controlled Release (1997), 44(2-3), 153-170

Although chemoembolization advantageously combines arterial embolization of the vascular supply of a neoplasm with controlled intra-arterial infusion of chemotherapeutic drug(s), its application is ... [more ▼]

Although chemoembolization advantageously combines arterial embolization of the vascular supply of a neoplasm with controlled intra-arterial infusion of chemotherapeutic drug(s), its application is limited by the lack of appropriate and reliable embolization materials. Recently, calibrated microspheres of poly(D,L)-lactide have proved to be promising in embolization. Nevertheless, repetitive chemoembolization requires the availability of microspheres degradable within a few days. For this purpose, microspheres consisting of a blend of two polyesters of a very different molecular weight (Mn =65 000 and 3500 in a 16:84 wt. ratio) have been prepared and injected in the renal arteries of rabbits. The in vivo fate of these two component microspheres has been compared by radiology and histology to microspheres prepared from the high molecular weight poly(D,L)-lactide. Furthermore, the in vivo degradation of the polymer has been measured by size exclusion chromatography after quantitative reextraction from the embolized kidney. Degradation kinetics has been compared to data previously reported in vitro. According to the observations performed during the in vivo study, the 50/50 microspheres appear more useful for the chemoembolization of tumors. [less ▲]

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See detailTextural properties and thermal stability of silica-zirconia aerogels
Pirard, René ULg; Bonhomme, Damien; Kolibos, Sofia et al

in Journal of Sol-Gel Science and Technology (1997), 8

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See detailLes armées d'Alexandre le Grand et les langues étrangères
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1997), 66

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See detailRheological characterization on the BaTiO3 sol-gel transition
Van Cantfort, Olivier; Brasseur, Alain; Michaux, Bernard et al

in Faraday Discussions (1997), 101

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See detailSarcoidosis: recognition and treatment guidelines
Kaye, O.; Ribbens, Clio ULg; Kahn, M. F. et al

in BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals & Gene Therapy (1997), 7(6), 441-447

Sarcoidosis is a systemic disorder of unknown aetiology characterised by noncaseating granulomas leading principally to bilateral hilar lymphadenopathies, pulmonary infiltration and skin and eye lesions ... [more ▼]

Sarcoidosis is a systemic disorder of unknown aetiology characterised by noncaseating granulomas leading principally to bilateral hilar lymphadenopathies, pulmonary infiltration and skin and eye lesions. Sarcoidosis may involve other organs, including peripheral lymph nodes, liver, spleen, nervous and musculoskeletal systems, heart, ear, nose and kidney. Although the clinical involvement of liver and heart is relatively uncommon, hepatic and cardiac granulomas are present at autopsy in about 70 to 80% and 25 to 50%, respectively, of patients with this disease. The diagnosis of sarcoidosis includes compatible clinical and/or radiological presentations and histological evidence of noninfectious and noncaseating epitheloid cell granulomas in the absence of other identifiable agents responsible for such histological lesions. Disease course is variable and usually characterised by frequent remissions, but it may become progressive and chronic in a small percentage of patients. The optimal treatment of sarcoidosis remains poorly defined. In patients with progressive pulmonary dysfunction as well as in those with severe extrapulmonary localisations, systemic corticosteroids usually represent the first approach, limited by long term toxicity and frequent relapses after treatment interruption. In the presence of refractory or corticosteroid-dependent forms of the disease, antimalarial drugs or low dosage methotrexate may be used with prolonged benefit. The indications for immunosuppressive agents such as azathioprine, chlorambucil, cyclophosphamide and cyclosporin are uncommon and limited because of potentially serious adverse effects and lack of information on their long term efficacy. In the case of ocular and limited cutaneous manifestations, local corticosteroid therapy may be useful. [less ▲]

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See detailIdentification of neurotensin-related peptides in human thymic epithelial cell membranes and relationship with MHC class I molecules
Vanneste, Yves; Ntodou-Thomé, Agnès; Vandersmissen, Eric et al

in Journal of Neuroimmunology (1997), 76

This study shows the expression at the cell surface of human thymic epithelial cells (TEC) of a neurotensin (NT)-like immunoreactivity. NT radio-immunoassay (RIA) revealed that cultured human TEC contain ... [more ▼]

This study shows the expression at the cell surface of human thymic epithelial cells (TEC) of a neurotensin (NT)-like immunoreactivity. NT radio-immunoassay (RIA) revealed that cultured human TEC contain ± 5 ng immunoreactive (ir) NT/106 cells, of which 5% is associated with plasma cell membranes. HPLC analysis of NT-ir present in human TEC showed a major peak of NT-ir corresponding to NT1–13. NT-ir was not detected in the supernatant of human TEC cultures. Using an affinity column prepared with a anti-MHC class I monoclonal antibody, NT-ir-related peptides were retained on the column and eluted together with MHC class I-related proteins. According to the elution time on HPLC of these peptides, they correspond to intact NT1–13, as well as to smaller fragments of NT1–13. [less ▲]

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See detailRoma ou Ruma ?
Rochette, Bruno ULg

in Maia (1997), 49

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See detailThe TEL gene products: nuclear phosphoproteins with DNA binding properties.
Poirel, H.; Oury, Cécile ULg; Carron, Clémence et al

in Oncogene (1997)

The human TEL gene is involved in several 12p13 chromosomal abnormalities present in various human hematological malignancies, the most frequent being the t(12;21)(p13;q22), specific for childhood acute ... [more ▼]

The human TEL gene is involved in several 12p13 chromosomal abnormalities present in various human hematological malignancies, the most frequent being the t(12;21)(p13;q22), specific for childhood acute lymphoblastic leukemia. The predicted product of TEL harbours an amino acid region similar to the ETS DNA binding domain. We now report the isolation of the murine TEL cDNA and the characterization of the human TEL proteins. Human and murine TEL proteins are particularly homologous within their aminoterminal regions and their ETS domains. TEL proteins are nuclear and display specific DNA binding activity toward classical ETS binding sites. In addition, we show that TEL mRNAs initiate translation at either of the two first inframe ATGs (codon 1 and 43) to encode 50 kDa and 57 kDa TEL proteins. In vivo, each of these primary translational products is modified by multiple phosphorylation events. [less ▲]

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See detailIntellectuels malgré eux
Denis, Benoît ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (1997), (79-81), 49-52

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See detailMultiple pregnancy-associated glycoproteins are secreted by day 100 sheep placenta
Xie, Sancai; Green, Jonathan; Bao, Bagna et al

in Biology of Reproduction (1997), 57(6), 1384-1393

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep ... [more ▼]

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep and other ruminants produce similar products. There is evidence, however, that these antigens, which are related structurally to the pepsinogens and other aspartic proteinases, are not single gene products but members of an extensive family. Here, the sequential use of ammonium sulfate precipitation and Sepharose blue, anion-exchange, and cation-exchange chromatographies, as well as isoelectric elution from a Mono P column, has allowed several PAG1-related molecules to be purified from the medium after culture of explants from Day 100 sheep placentas. Each of these PAGs cross-reacted to a varying extent with a panel of three different anti-PAG1 antisera. Four of them, all of which were major secretory products of the placenta, were subjected to amino-terminal microsequencing. Although each was related to ovine (ov) PAG1, none was identical. Reverse transcription-polymerase chain reaction was then used to amplify PAG1-related cDNA from Day 100 placental RNA. Seven novel full-length cDNA, all distinct from ovPAG1, were identified from 25 cDNA selected for sequencing. Only two of these (ovPAG3 and ovPAG7) encoded polypeptides identical in sequence at their inferred amino termini to one of the PAGs (ovPAG65) purified from explant cultures. Even so, they were only 84% identical in overall sequence. The remaining five cDNA were unique. In situ hybridization analysis revealed that expression of ovPAG3 and ovPAG7, like that of ovPAG1, is confined to trophoblast binucleate cells. The data confirm that at Day 100 of pregnancy the ovine placenta produces many different PAGs, which differ considerably in sequence and immunological cross-reactivity. [less ▲]

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See detailLat. collatrare
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (1997), 56

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See detailLes pesticides: effets endocriniens et cancérogènes chez l'Homme
Charlier, Corinne ULg; Plomteux, Guy ULg

in Toxicorama (1997), IX

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See detailLa nouvelle réglementation du concordat judiciaire
Thirion, Nicolas ULg

in Actualités du Droit (1997), (3), 379-420

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See detailPeptides in membranes: tipping the balance of membrane stability.
Brasseur, Robert ULg; Pillot, T.; Lins, Laurence ULg et al

in Trends in biochemical sciences (1997), 22(5), 167-71

This review describes a class of peptides that associate with lipids in membranes and are commonly known as 'oblique-orientated peptides'. Owing to an asymmetric distribution of hydrophobic residues along ... [more ▼]

This review describes a class of peptides that associate with lipids in membranes and are commonly known as 'oblique-orientated peptides'. Owing to an asymmetric distribution of hydrophobic residues along the axis of the alpha-helix, such peptides can destabilize membranes or lipid cores, thereby facilitating such cellular processes as vesicular fusion or protein transport across subcellular compartments, as well as remodelling of lipid cores. [less ▲]

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See detailFrom an architectural sketch to its semantic representation
Leclercq, Pierre ULg

in International Journal of Construction Information Technology (1997), 4(2), 67-84

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See detailEvaluation d'un programme intensif de revalidation pour travailleurs lombalgiques
Mairiaux, Philippe ULg; Oblin, Marc

in Archives des Maladies Professionnelles et de Médecine du Travail (1997), 58(5), 432439

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See detailFast and slow tracks in lysozyme folding: Insight into the role of domains in the folding process
Matagne, André ULg; Radford, S. E.; Dobson, C. M.

in Journal of Molecular Biology (1997), 267(5), 1068-1074

The folding of lysozyme involves parallel events in which hydrogen exchange kinetics indicate the development of persistent structure at very different rates. We have monitored directly the kinetics of ... [more ▼]

The folding of lysozyme involves parallel events in which hydrogen exchange kinetics indicate the development of persistent structure at very different rates. We have monitored directly the kinetics of formation of the native molecule by the binding of a fluorescently labelled inhibitor, MeU-diNAG (4-methylumbelliferyl-N,N'-diacetyl-beta-D-chitobioside). The data show that native character monitored in this way also develops with different timescales. Although the rate determining step on the slow pathway (similar to 75% of molecules at pH 5.5, 20 degrees C) can be attributed to the need to reorganise structure formed early in the folding process, the data indicate that the rate determining step on the fast track (involving similar to 25% of molecules) involves the docking of the two constituent domains of the protein. In the fast folding track the data are consistent with a model in which each domain forms persistent structure prier to their docking in a locally cooperative manner on a timescale comparable to the folding of small single domain proteins. (C) 1997 Academic Press Limited. [less ▲]

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See detailLe diagnostic de la reproduction: fertilité, gestation, anœstrus
Delahaut, Philippe; Sulon, Joseph ULg; Ectors, Francis et al

in Cahiers Agricultures (1997), 6

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