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See detailLes sartans face aux inhibiteurs de l'enzyme de conversion de l'angiotensine en présence d'une hypertension artérielle
Krzesinski, Jean-Marie ULg; Sternon, J.

in Revue Médicale de Bruxelles (2000), 21(3), 170-177

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See detailDonor lymphocyte infusion to eradicate recurrent host hematopoiesis after allogeneic BMT for sickle cell disease.
Baron, Frédéric ULg; Dresse, Marie-Françoise ULg; Beguin, Yves ULg

in Transfusion (2000), 40(9), 1071-3

BACKGROUND: Donor lymphocyte infusion (DLI) is currently standard therapy for relapse of malignancies after allogeneic BMT. Several observations suggest that both normal and leukemic progenitor cells of ... [more ▼]

BACKGROUND: Donor lymphocyte infusion (DLI) is currently standard therapy for relapse of malignancies after allogeneic BMT. Several observations suggest that both normal and leukemic progenitor cells of host origin constitute effective target cells for donor-derived lymphocytes. To prevent relapse of sickle cell disease (SCD), a child with evidence of decreasing mixed chimerism received DLIs 8 months after allogeneic BMT for SCD. CASE REPORT: A 4-year-old child who was homozygous for SCD underwent a transplantation of bone marrow from his fully HLA-matched sister. Routine detection of sex chromosomes in bone marrow cells evidenced decreasing mixed chimerism, which heralded a probably imminent recurrence of the disease. The patient received two DLIs in graded incremental doses on Days 234 and 267. One month later, he developed grade 2 acute GVHD that responded well to corticosteroids and cyclosporine. RESULTS: DLI resulted in complete donor chimerism within 2 months of the second infusion. Now, 2 years after the second DLI, the patient is in excellent condition, with normal Hb and excellent growth and development. CONCLUSION: This is the first report of successful use of DLI in a patient with probable imminent SCD recurrence after allogeneic BMT. It shows that DLI can displace residual host HPCs in case of recurrence of nonmalignant disease after allogeneic BMT. [less ▲]

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See detailLa maladie de Kashin-Beck et le milieu rural au Tibet: un problème agri-environnemental
Haubruge, Eric ULg; Chasseur, Camille; Mathieu, Françoise et al

in Cahiers Agricultures (2000), 9

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See detailLa prise en charge de patients Alzheimer au stade débutant : Rôle d'un centre de jour
Adam, Stéphane ULg; Van der Linden, Martial ULg

in Rééducation Orthophonique (2000), 201

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See detailSyntaxe et sens de la tournure védique prathamam jayamânah
Swennen, Philippe ULg

in A.I.O.N. Annali dell'Istituto Universitario Orientale di Napoli. Sezione filologico-letteraria (2000), 60-61

The Vedic locution prathamam jâjyamânah is a syntagm, where the first word, used as an adverb, means that the action expressed by the participle happens just before the action of the main verb of the ... [more ▼]

The Vedic locution prathamam jâjyamânah is a syntagm, where the first word, used as an adverb, means that the action expressed by the participle happens just before the action of the main verb of the sentence. Once this rule is established, other examples of this use of prathamam can be identified. This turn, very rare in the texts, was archaic and finally disappeared. [less ▲]

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See detailAnalysis of plasma IGF-I hormone levels in Holstein-Friesian Heifers
Horvai-Szabo, M.; Renaville, Robert ULg; Dohy, J.

in Journal of Dairy Science (2000), 83(suppl 1), 48

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See detailBase Plate in Bending and Anchor Bolts in Tension
Wald, Frantisek; Jaspart, Jean-Pierre ULg; sokol, Z et al

in Journal of Constructional Steel Research (2000)

The paper describes behaviour of the base plate in bending and the anchor bolts in tension, which is the major component of the base plate connection. The analytical model predicts the component ... [more ▼]

The paper describes behaviour of the base plate in bending and the anchor bolts in tension, which is the major component of the base plate connection. The analytical model predicts the component characteristics — the resistance and the stiffness. It is described how the quality of the behaviour is guided by the contact between the base plate and the concrete surface. The presented analytical prediction model is verified on tests and FE simulation. [less ▲]

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See detailEvaluation of Accuracy of Pulse Oximetry in Newborn Calves
Uystepruyst, Christophe; Coghe, Joost; Bureau, Fabrice ULg et al

in Veterinary Journal (2000), 159(1), 71-76

In human medicine, pulse oximetry is widely used to measure non-invasively and accurately the percentage of oxygen saturation of arterial haemoglobin (SpO(2)). Recently, pulse oximetry has been used in ... [more ▼]

In human medicine, pulse oximetry is widely used to measure non-invasively and accurately the percentage of oxygen saturation of arterial haemoglobin (SpO(2)). Recently, pulse oximetry has been used in calves, but its accuracy has not been evaluated in newborn calves. The purpose of this study was to evaluate the accuracy of a pulse oximeter in newborn calves by comparing SpO(2) with arterial oxyhaemoglobin saturation (SaO(2)) obtained by use of a blood gas analyser. Fifty-five newborn calves were investigated from birth to 20 days old. Pulse oximetry readings and arterial blood samples were performed 5, 15, 30, 45, 60 min, 2, 3, 6, 12, 24 h and 1 and 3 weeks after birth. The transmission-type sensors of the pulse oximeter were fixed at the recommended site in the bovine species (at the base of the calf tail, where the skin had been shaved and was not pigmented) and arterial blood samples were withdrawn from the subclavian artery and analysed for SaO(2). Five-hundred paired data of SaO(2) and mean SpO(2)(mSpO(2)) were collected. Linear regression of the pooled data indicated a highly significant correlation of mSpO(2) with SaO(2) (r = 0.87;P< 0.001; mSpO(2) = 15.8 + 0.84 SaO(2)). The overall data bias value was positive (+2.1%), which indicated that the pulse oximeter tended to overestimate the SaO(2). The bias value for each SaO(2) category tended to become higher for lower ranges of SaO(2). Precision was also lower when SaO(2) values were low. The lower the SaO(2) value, the higher the positive bias (overestimation) and the lower the precision. These results suggest that pulse oximetry provides a relatively accurate non-invasive, immediate and portable method to monitor SaO(2) and to evaluate objectively the pulmonary function effectiveness in newborn calves during their adaptation to extra-uterine life. [less ▲]

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See detailComparative Effects Of Deltamethrin And Neem Kernel Solution Treatments On Diamondback Moth And Cotesia Plutellae (Hym., Braconidae) Parasitoid Populations In The Cotonou Peri-Urban Area In Benin
Goudegnon, Ae.; Kirk, Aa.; Schiffers, Bruno ULg et al

in Journal of Applied Entomology-Zeitschrift Fur Angewandte Entomologie (2000), 124(3-4), 141-144

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See detailCoumarinic derivatives as mechanism-based inhibitors of α-chymotrypsin and human leukocyte elastase
Pochet, Lionel; Doucet, Caroline; Dive, Georges ULg et al

in Bioorganic & Medicinal Chemistry (2000), 8(6), 1489-1501

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See detailThe effect of electron-phonon interaction in iron-doped III-V cubic semiconductors
Colignon, David ULg; Kartheuser, Eduard ULg; Villeret, Murielle

in Journal of Physics : Condensed Matter (2000), 12(12), 2691-2699

A theoretical study of optical absorption and emission measurements of Fe2+ as a substitutional impurity in InP and GaP is presented. A new interpretation of the low-temperature absorption spectrum is ... [more ▼]

A theoretical study of optical absorption and emission measurements of Fe2+ as a substitutional impurity in InP and GaP is presented. A new interpretation of the low-temperature absorption spectrum is proposed based on a weak Jahn-Teller interaction between the electronic excited states and a local gap mode of Gamma(5) symmetry. The model also includes the crystal potential, hybridization with the orbitals of the ligands of the host crystal, spin-orbit interaction and a weak dynamic Jahn-Teller coupling of the orbital ground state of Fe2+ with transverse acoustic phonons of Gamma(3) symmetry. The theoretical model describes with good accuracy the measured positions and relative intensities of the spectral lines. In addition, the mass dependence of the local gap mode of Gamma(5) symmetry reproduces the general features of the fine structures associated with the isotopic shifts of the zero-phonon line and the contribution to the isotopic shifts arising from the difference in zero-point energy between the initial and final states of the transition is evaluated. [less ▲]

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See detailCrystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor.
Concha, N. O.; Janson, C. A.; Rowling, P. et al

in Biochemistry (2000), 39(15), 4288-98

Metallo beta-lactamase enzymes confer antibiotic resistance to bacteria by catalyzing the hydrolysis of beta-lactam antibiotics. This relatively new form of resistance is spreading unchallenged as there ... [more ▼]

Metallo beta-lactamase enzymes confer antibiotic resistance to bacteria by catalyzing the hydrolysis of beta-lactam antibiotics. This relatively new form of resistance is spreading unchallenged as there is a current lack of potent and selective inhibitors of metallo beta-lactamases. Reported here are the crystal structures of the native IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor, 2-[5-(1-tetrazolylmethyl)thien-3-yl]-N-[2-(mercaptomethyl)-4 -(phenylb utyrylglycine)]. The structures were determined by molecular replacement, and refined to 3.1 A (native) and 2.0 A (complex) resolution. Binding of the inhibitor in the active site induces a conformational change that results in closing of the flap and transforms the active site groove into a tunnel-shaped cavity enclosing 83% of the solvent accessible surface area of the inhibitor. The inhibitor binds in the active site through interactions with residues that are conserved among metallo beta-lactamases; the inhibitor's carboxylate group interacts with Lys161, and the main chain amide nitrogen of Asn167. In the "oxyanion hole", the amide carbonyl oxygen of the inhibitor interacts through a water molecule with the side chain of Asn167, the inhibitor's thiolate bridges the two Zn(II) ions in the active site displacing the bridging water, and the phenylbutyryl side chain binds in a hydrophobic pocket (S1) at the base of the flap. The flap is displaced 2.9 A compared to the unbound structure, allowing Trp28 to interact edge-to-face with the inhibitor's thiophene ring. The similarities between this inhibitor and the beta-lactam substrates suggest a mode of substrate binding and the role of the conserved residues in the active site. It appears that the metallo beta-lactamases bind their substrates by establishing a subset of binding interactions near the catalytic center with conserved characteristic chemical groups of the beta-lactam substrates. These interactions are complemented by additional nonspecific binding between the more variable groups in the substrates and the flexible flap. This unique mode of binding of the mercaptocarboxylate inhibitor in the enzyme active site provides a binding model for metallo beta-lactamase inhibition with utility for future drug design. [less ▲]

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See detailTissue distribution, autoradiography, and metabolism of 4-(2'-methoxyphenyl)-1-[2' -[N-2"-pyridinyl)-p-[(18)F]fluorobenzamido]ethyl]piperazine (p-[(18)F]MPPF), a new serotonin 5-HT(1A) antagonist for positron emission tomography: An In vivo study in rats.
Plenevaux, Alain ULg; Weissmann, D.; Aerts, Joël ULg et al

in Journal of Neurochemistry (2000), 75(2), 803-11

The in vivo behavior of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-[(18)F]fluorobenzamido ]ethyl]-piperazine (p-[(18)F]MPPF), a new serotonin 5-HT(1A) antagonist, was studied in awake, freely moving ... [more ▼]

The in vivo behavior of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-[(18)F]fluorobenzamido ]ethyl]-piperazine (p-[(18)F]MPPF), a new serotonin 5-HT(1A) antagonist, was studied in awake, freely moving rats. Biodistribution studies showed that the carbon-fluorine bond was stable in vivo, that this compound was able to cross the blood-brain barrier, and that a general diffusion equilibrium could account for the availability of the tracer. The great quantity of highly polar metabolites found in plasma did not contribute to the small amounts of metabolites found in hippocampus, frontal cortex, and cerebellum. Exvivo p-[(18)F]MPPF and in vitro 8-hydroxy-2-(di-n-[(3)H]propylamino)tetralin autoradiography were compared both qualitatively and quantitatively. Qualitative evaluation proved that the same brain regions were labeled and that the p-[(18)F]MPPF labeling is (a) in total agreement with the known distribution of 5-HT(1A) receptors in rats and (b) characterized by very low nonspecific binding. Quantitative comparison demonstrated that the in vivo labeling pattern obtained with p-[(18)F]MPPF cannot be explained by differences in regional blood flow, capillary density, or permeability. The 5-HT(1A) specificity of p-[(18)F]MPPF and binding reversibility were confirmed in vivo with displacement experiments. Thus, this compound can be used to evaluate parameters characterizing 5-HT(1A) binding sites in the brain. [less ▲]

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See detailTuna and dolphin associations in the Northeast Atlantic: Evidence of different ecological niches from stable isotope and heavy metal measurements
Das, Krishna ULg; Lepoint, Gilles ULg; Loizeau, Véronique et al

in Marine Pollution Bulletin (2000), 40

Associations of tunas and dolphins in the wild are quite frequent events and the question arises how predators requiring similar diet in the same habitat share their environmental resources. As isotopic ... [more ▼]

Associations of tunas and dolphins in the wild are quite frequent events and the question arises how predators requiring similar diet in the same habitat share their environmental resources. As isotopic composition of an animal is related to that of its preys, stable isotopes (13C/12C and 15N/14N) analyses were performed in three predator species from the Northeast Atlantic: the striped dolphin, Stenella coeruleoalba, the common dolphin Delphinus delphis, and the albacore tuna, Thunnus alalunga, and compared to their previously described stomach content. Heavy metals (Cd, Zn, Cu and Fe) are mainly transferred through the diet and so, have been determined in the tissues of the animals. Tunas muscles display higher delta15N than in common and striped dolphins (mean: 11.4 0/00 vs. 10.3 0/00 and 10.4 0/00, respectively) which reflects its higher trophic level nutrition. Higher delta13C are found in common (-18.4 0/00) and striped dolphin (-18.10/00) muscles than in albacore tuna (-19.3 0/00) likely in relation with its migratory pattern. The most striking feature is the presence of two levels of cadmium concentrations in the livers of the tunas (32 mg kg-1 dry weight vs. 5 mg kg-1 dry weight). These two groups also differ by their iron concentrations and their delta15N and delta 13C liver values. These results suggest that in the Biscay Bay, tunas occupy two different ecological niches likely based on different squid input in their diet. [less ▲]

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See detailTEP et tumeurs endocrines
Rigo, Pierre ULg; Belhocine, Tarik; Hustinx, Roland ULg et al

in Médecine Nucléaire : Imagerie Fonctionnelle et Métabolique (2000), 24(5), 275-282

Les auteurs passent en revue les indications de la TEP et en particulier du 18FDG dans l'évaluation des diverses tumeurs endocrines de la thyroïde, des parathyroïdes, des surrénales et de l'hyophyse. Les ... [more ▼]

Les auteurs passent en revue les indications de la TEP et en particulier du 18FDG dans l'évaluation des diverses tumeurs endocrines de la thyroïde, des parathyroïdes, des surrénales et de l'hyophyse. Les tumeurs neuroendocrines, gastroentéropancréatiques et carcinoïdes, sont également analysées. Habituellement, les tumeurs différenciées ayant une faible activité métabolique et proliférative, elles ne fixent que peu le FDG. Dans l'évaluation des tumeurs endocrines, la TEP au FDG n'intervient en général pas en première intention mais elle joue un rôle complémentaire d'autres scintigraphies spécifiques. [less ▲]

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See detailCongestion Control for Layered Multicast Transmission
El Khayat, Ibtissam; Leduc, Guy ULg

in Networking and Information Systems Journal (2000), 3(3-4), 559-573

Heterogeneity of receivers makes it hard to control congestion for multicast transmission. Using hierarchical layering of the information is one of the most elegant and efficient approach to tackle this ... [more ▼]

Heterogeneity of receivers makes it hard to control congestion for multicast transmission. Using hierarchical layering of the information is one of the most elegant and efficient approach to tackle this problem. The proposed algorithm is based on this principle and has three objectives: to fulfill intra-session fairness, i.e. between different receivers of the same session; to be fair towards TCP; to fulfill inter-session fairness, i.e. same throughputs (and not number of layers) to concurrent sessions. [less ▲]

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See detailDetermination Of The Methionine Requirement Of Growing Double-Muscled Belgian Blue Bulls With A Three-Step Method
Froidmont, Eric; Beckers, Yves ULg; Thewis, André ULg

in Journal of Animal Science (2000), 78(1), 233-241

The three-step technique was used to determine the requirements of total amino acids (TAA) and the first-limiting amino acid (AA) in growing double- muscled Belgian Blue bulls (BBb). In Exp. 1, three ... [more ▼]

The three-step technique was used to determine the requirements of total amino acids (TAA) and the first-limiting amino acid (AA) in growing double- muscled Belgian Blue bulls (BBb). In Exp. 1, three double-muscled BBb weighing initially 306 ± 28 kg received a basal diet consisting of 30% meadow hay and 70% concentrate that was poor in digestible protein but had adequate NE because of continuous infusion of dextrose into the duodenum. The intestinal apparent digestibility of essential AA (EAA) was defined according to their duodenal and ileal flows. It averaged 72% but varied between 60% for Met and 79% for Arg. In Exp. 2, five double-muscled BBb (334 ± 22 kg) received the same diet supplemented with duodenal infusions of dextrose and four doses of Na-caseinate (28, 56, 84, and 112% of intestinal digestible dietary AA) in a 4 × 4 Latin square design with one additional animal. Nitrogen retention for the basal diet alone and the four increasing supplements of Na-caseinate reached 49, 61, 70, 80, and 86 g/d, respectively. Nitrogen utilization improved from 34.3% without Na-caseinate supplementation to a maximum of 40.6%, with the third dose supplying 788 g/d of apparently digestible AA. Based on patterns of plasma concentrations, Met, Phe, and Arg were probably the limiting AA when animals optimized N utilization. In Exp. 3, six double-muscled BBb (315 ± 25 kg) fed the basal diet received duodenal infusions of dextrose and AA, equivalent to the third dose in Exp. 2, except for digestible Met (9.3, 14.4, 18.4, 22.4, 26.4, and 30.4 g/d) in a 6 × 6 Latin square design. The Met requirement was close to 26.4 g/d on the basis of N retention. [less ▲]

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See detailUsing the classification model of an electronic nose to assign unknown malodours to environmental sources and to monitor them continuously
Nicolas, Jacques ULg; Romain, Anne-Claude ULg; Wiertz, Véronique et al

in Sensors and actuators. B, Chemical (2000), 69(3), 366-371

The paper provides some considerations resulting from measurements with electronic noses around real sources of malodour in the environment: compost facilities, printing houses, paint shops, waste water ... [more ▼]

The paper provides some considerations resulting from measurements with electronic noses around real sources of malodour in the environment: compost facilities, printing houses, paint shops, waste water treatment plants, rendering plants, settling ponds of sugar factories. The study aims at supplying the concrete information requested by the final user in the field: either a warning signal when the malodour level exceeds some given threshold value, the identification of the source of an odour detected on site, or on-line identification and monitoring of an odour in the field. Very simple instruments are used, either in the laboratory or directly in the field, with a home-made portable e-nose, based on tin oxide sensors. Even with such simple operating conditions, the classification results with DA and PCA are fairly good. The classification functions calibrated with the statistical procedure, on the basis of the learning phase, are used to recognise and to monitor a given malodour. This odour is sometimes mixed with other odorous interferences in the field. The observations reveal some features useful in the frame of the development of a field detector. [less ▲]

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See detail2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide: evaluation of the spin trapping properties
Olive, Gilles ULg; Mercier, Anne; Le Moigne, François et al

in Free Radical Biology & Medicine (2000), 28(3), 403-408

The 2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-l-oxide (EMPO), an easily prepared pyrroline-Noxide has been tested as a free radical scavenger. Spin adducts of superoxide, hydroxyl radical, and ... [more ▼]

The 2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-l-oxide (EMPO), an easily prepared pyrroline-Noxide has been tested as a free radical scavenger. Spin adducts of superoxide, hydroxyl radical, and other free radicals were characterized in phosphate buffer at pH 7.0 and 5.6. At pH 7 in phosphate buffer, the EMPO/O2 2• spin adduct was estimated to be about five times more persistent than its DMPO analogue. Furthermore, its decay does not produce the EMPO/HO• adduct. [less ▲]

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See detailLe potentiel evoque cognitif P300 (I): aspects theorique et psychobiologique.
Hansenne, Michel ULg

in Neurophysiologie Clinique = Clinical Neurophysiology (2000), 30(4), 191-210

The P300 is a positive wave which arises when an attended stimulus is detected. Its parameters depend on a number of variables, in particular the subject's mental state, the task that has to be ... [more ▼]

The P300 is a positive wave which arises when an attended stimulus is detected. Its parameters depend on a number of variables, in particular the subject's mental state, the task that has to be accomplished, the significance of the stimulus, and the degree of attention. It can be recorded with accuracy, and the different stages of information processing can therefore be analyzed. The P300 wave shows the modifications in neuronal activity which take place during the cognitive process: P300 latency provides an indirect indication of the duration of the processes involved in stimulus discrimination while its amplitude, which is influenced by a number of variables, provides an index of the intensity of the energetic activation or arousal involved. The P300 wave consists of several components which reflect distinct information-processing events (P3a, P3b, P3e, P-SR, P-CR). According to the theoretical models, it is hypothesized that P300 could either represent the adaptation of the working memory to further environmental input ('context updating'), or indicate a closing process ('context closure') in information processing. As regards the physiological aspect of P300 and its association with cortical networks, various studies have suggested that several cortical generators of P300 may co-exist: the medial temporal lobe, the temporo-parietal junction, and the medial and lateral frontal lobe. Psychopharmacological studies have shown that different neurotransmitter systems are involved in the generation and modulation of P300, namely the cholinergic, noradrenergic, dopaminergic, serotoninergic and gabaergic systems. It appears that the noradrenergic agonists increase the amplitude of P300, dopaminergic agonists may have a biphasic effect (increase/reduction), while cholinergic antagonists and gabaergic agonists reduce P300 amplitude and prolong its latency. [less ▲]

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See detailCharacterization Of The Lipid-Binding Properties And Lipoprotein Lipase Inhibition Of A Novel Apolipoprotein C-Iii Variant Ala23thr
Liu, Hq.; Labeur, C.; Xu, Cf. et al

in Journal of Lipid Research (2000), 41(11), 9201-12

The physicochemical properties of recombinant wild type and three site-directed mutants of apolipoprotein C-III (apoC-III), designed by molecular modeling to alter specific amino acid residues implicated ... [more ▼]

The physicochemical properties of recombinant wild type and three site-directed mutants of apolipoprotein C-III (apoC-III), designed by molecular modeling to alter specific amino acid residues implicated in lipid binding (L9T/T20L, F64A/W65A) or LPL inhibition (K21A), were compared. Relative lipid binding efficiencies to dimyristoylphosphatidylcholine (DMPC) were L9T/T20L > WT >K21A > F64A/W65A with an inverse correlation with size of the discoidal complexes formed. Physicochemical analysis (Trp fluorescence, circular dichroism, and GdnHCl denaturation) suggests that L9T/T20L forms tighter and more stable lipid complexes with phospholipids, while F64A/W65A associates less tightly. Lipid displacement properties were tested by gel-filtrating apoE:dipalmitoylphosphatidylcholine (DPPC) discoidal complexes mixed with the various apoC-III variants. All apoC-III proteins bound to the apoE:DPPC complexes; the amount of apoE displaced from the complex was dependent on the apoC-III lipid binding affinity. All apoC-III proteins inhibited LPL in the presence or absence of apoC-II, with F64A/W65A displaying the most inhibition, suggesting that apoC-III inhibition of LPL is independent of lipid binding and therefore of apoC-II displacement. Taken together. these data suggest that the hydrophobic residues F64 and W65 are crucial for the lipid binding properties of apoC-III and that redistribution of the N-terminal helix of apoC-III (L9T/T20L) enhances the stability of the lipid-bound protein, while LPL inhibition by apoC-III is likely to be due to protein:protein interactions. [less ▲]

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See detailHormonal control of proliferation in meristematic agglomerates of Eucalyptus camaldulensis Dehn
Arezki, Ouoimare; Boxus, Philippe; Kevers, Claire ULg et al

in In Vitro Cellular & Developmental Biology-Plant (2000), 36(5), 398-401

Eucalyptus camaldulensis can he micropropagated through so-called meristematic agglomerates (MAs). MAs (4-6 mm diameter) are dense shoot clusters initiated by the Outgrowth of numerous successive buds ... [more ▼]

Eucalyptus camaldulensis can he micropropagated through so-called meristematic agglomerates (MAs). MAs (4-6 mm diameter) are dense shoot clusters initiated by the Outgrowth of numerous successive buds. Their reddish nature is associated with an increase ill their endogenous cytokinin level during the exponential phase of growth. A simultaneous decrease in the auxin level favors a high cytokinin/auxin ratio. A low level of polyamines occurs at the time of the lowest level of auxins. Slow hormone release by activated charcoal plays a role in this very prolific organogenesis. [less ▲]

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See detailLes populations de grands mammifères et d'autruches du Parc National de Zakouma au Tchad : statuts et tendances évolutives
Dejace, Philippe; Gauthier, Laure; Bouché, Philippe ULg

in Revue d'Ecologie (2000), 55

Zakouma National Park is situated in the south-east of Chad Republic and covers more than 3 000 km2. Rehabilitated in 1989, it is certainly one of the best-preserved wildlife sanctuaries in Sahelian ... [more ▼]

Zakouma National Park is situated in the south-east of Chad Republic and covers more than 3 000 km2. Rehabilitated in 1989, it is certainly one of the best-preserved wildlife sanctuaries in Sahelian Africa. Aerial census shows that most of its original fauna is still present, making the Park an exception in the region despite the recent troubled history of this country. Total population estimates of elephants, buffaloes and topis are given and distribution maps are presented for eleven species. Results are compared with two previous estimates. Except for the ostrich and perhaps the warthog, probably in regression, the populations of two species are stable (hartebeest and giraffe) while the others are clearly increasing (buffalo, topi, elephant and roan antelope). Those encouraging results are the consequence of the remoteness of the park, wich is far from any big town, and also overflooded and isolated during the wet season. Those facts contribute to maintain the human pressure at a sustainable level. [less ▲]

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See detailThe cognitive management of daily life activities in patients with mild to moderate Alzheimer's disease me in a day care centre : A case report
Adam, Stéphane ULg; Van der Linden, Martial ULg; Juillerat, Anne- Claude et al

in Neuropsychological Rehabilitation (2000), 10(5), 485-509

The day care centre appears to be a structure especially well suited for the management of mild to moderate Alzheimer patients. It constitutes a place in which performance in everyday life activities can ... [more ▼]

The day care centre appears to be a structure especially well suited for the management of mild to moderate Alzheimer patients. It constitutes a place in which performance in everyday life activities can be explored, and optimisation strategies can be installed before they are used at home. Another objective of the day care centre might also be to provide caregivers with support and ease the burden that the daily care of a demented patient represents. Finally, it may also help to alleviate the patient's loneliness. In this perspective, we describe the general organisation of the recently-created day care centre at the University Hospital of Liege. We also present the assessment and intervention programme which was conducted in this day care centre in order to reduce the generalised apathy and depressed mood observed in a 70-year-old Alzheimer patient (AM). This programme aimed at restoring a leisure activity (knitting) at home by proposing several adaptations designed to minimise the impact of AM's cognitive deficits on knitting activity. While an aggravation of her memory deficits was observed, the intervention significantly decreased AM's apathy and depressed mood as well as her husband's burden. [less ▲]

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See detailZwitterionic (pyrrolidine-2,2-diyl)bisphosphonic acid at 100, 150 and 293K
Olive, Gilles ULg; Ellis, Dianne D; Siri, Didier et al

in Acta Crystallographica Section C-Crystal Structure Communications (2000), C56(6), 720-722

Structure of the zwitterionic pyrrolidine-2,2-diylbis(phosphonic acid) at 100, 150 and 293 K

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See detailBlood Oxygen Binding in Double-Muscled Calves and Dairy Calves with Conventional Muscle Conformation
Cambier, Carole ULg; Clerbaux, T.; Detry, B. et al

in American Journal of Veterinary Research (2000), 61(3), 299-304

OBJECTIVE: To assess in vivo blood oxygen binding in double-muscled calves and dairy calves with conventional muscle conformation. ANIMALS: 58 dairy and 48 double-muscled calves. PROCEDURE: Calves were ... [more ▼]

OBJECTIVE: To assess in vivo blood oxygen binding in double-muscled calves and dairy calves with conventional muscle conformation. ANIMALS: 58 dairy and 48 double-muscled calves. PROCEDURE: Calves were classified as neonatal (24 hours old) or older calves (2 to 26 days old). Venous and arterial blood samples were collected, and hemoglobin concentration, pH, PCO2, and PO2 were determined. Blood oxygen equilibrium curves (OEC) under standard conditions were constructed, and the oxygen exchange fraction (OEF) and the amount of oxygen released at the tissue level by 100 ml of blood (OEF Vol%) were calculated. RESULTS: In each breed, partial pressure of oxygen at 50% saturation of hemoglobin (P50) under standard conditions was significantly higher in older than in neonatal calves, indicating a right shift in OEC with age. Venous P50 was significantly lower in neonatal double-muscled calves than in neonatal dairy calves, but arterial and venous P50 were significantly higher in older double-muscled calves than in older dairy calves. In double-muscled, but not in dairy, calves, OEF was significantly higher in older than in neonatal calves. In neonatal calves, OEF Vol% was not significantly different between breeds, but OEF Vol% was significantly higher in older double-muscled calves than in older dairy calves. CONCLUSIONS AND CLINICAL RELEVANCE: The lower OEF in neonatal double-muscled calves, compared with dairy calves, could contribute to the higher sensitivity of double-muscled calves to hypoxia. Blood oxygen affinity decreased with age, but OEF and OEF Vol% were unchanged with age in dairy calves, whereas they increased with age in double-muscled calves [less ▲]

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See detailAspects physiologiques de la sécrétion laitière par la mamelle bovine
Dosogne, H; Arendt, J; Gabriel, Annick ULg et al

in Annales de Médecine Vétérinaire (2000), 144

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See detailBand-by-band decompositions of the Born effective charges
Ghosez, Philippe ULg; Gonze, X.

in Journal of Physics : Condensed Matter (2000), 12(43), 9179-9188

The Born effective charge, Z*, that describes the polarization created by collective atomic displacements, can be computed from first principles following different techniques. We establish the ... [more ▼]

The Born effective charge, Z*, that describes the polarization created by collective atomic displacements, can be computed from first principles following different techniques. We establish the connections existing between these different formulations, and analyse the related band-by-band decompositions. We show that unlike for the full Z*, the different band-by-band values are not equal, and emphasize that one of them has a natural physical meaning in terms of Wannier functions. [less ▲]

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See detailIntestinal maturation induced by spermine in young animals
Peulen, Olivier ULg; Deloyer, P; Grandfils, Christian ULg et al

in Livestock Production Science (2000), 66

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See detailLes arcanes de la prescription de l'action publique
Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2000)

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See detailEnzyme-Histochemical Detection of a Chymase-Like Proteinase within Bovine Mucosal and Connective Tissue Mast Cells
Jolly, Sandra ULg; Detilleux, Johann ULg; Coignoul, Freddy ULg et al

in Journal of Comparative Pathology (2000), 122(Feb-Apr), 155-162

The presence of chymase-like proteinase in bovine mast cells was investigated by an enzyme-histochemical technique (naphthol-AS-D-chloroacetate as substrate) in normal skin, primary bronchus, lung and ... [more ▼]

The presence of chymase-like proteinase in bovine mast cells was investigated by an enzyme-histochemical technique (naphthol-AS-D-chloroacetate as substrate) in normal skin, primary bronchus, lung and duodenum. The counts and distribution of chymase-positive and toluidine blue-positive mast cells were compared by means of successive staining. Mast cells with chymase-like activity were detected in all areas, but their proportion was greater in connective than mucosal tissues, with the exception of the skin. These results contrast with those obtained in rodents, in which chymase-like proteinases are detected in all tissues and also in all mast cells. Bovine mast cells are closer to those of human beings, in which chymase-containing mast cells predominate in connective tissues, including skin. The results suggest that more than one chymase subset is present, at least in duodenum. The possible occurrence of dual-specific chymase mast cells, as in other ruminants, is discussed. [less ▲]

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See detailTreatment outcome in infant acute lymphoblastic leukemia
Ferster, A; Benoit, Y; Francotte, N et al

in Blood (2000), 95(8), 2729-31

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See detailLa place quantitative et qualitative de la viande dans notre alimentation.
Mary, Arnaud; Sindic, Marianne ULg

in Dieta (2000), (22), 6-11

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See detailNeural mechanisms of antinociceptive effects of hypnosis.
Faymonville, Marie ULg; Laureys, Steven ULg; Degueldre, Christian ULg et al

in Anesthesiology (2000), 92(5), 1257-67

BACKGROUND: The neural mechanisms underlying the modulation of pain perception by hypnosis remain obscure. In this study, we used positron emission tomography in 11 healthy volunteers to identify the ... [more ▼]

BACKGROUND: The neural mechanisms underlying the modulation of pain perception by hypnosis remain obscure. In this study, we used positron emission tomography in 11 healthy volunteers to identify the brain areas in which hypnosis modulates cerebral responses to a noxious stimulus. METHODS: The protocol used a factorial design with two factors: state (hypnotic state, resting state, mental imagery) and stimulation (warm non-noxious vs. hot noxious stimuli applied to right thenar eminence). Two cerebral blood flow scans were obtained with the 15O-water technique during each condition. After each scan, the subject was asked to rate pain sensation and unpleasantness. Statistical parametric mapping was used to determine the main effects of noxious stimulation and hypnotic state as well as state-by-stimulation interactions (i.e., brain areas that would be more or less activated in hypnosis than in control conditions, under noxious stimulation). RESULTS: Hypnosis decreased both pain sensation and the unpleasantness of noxious stimuli. Noxious stimulation caused an increase in regional cerebral blood flow in the thalamic nuclei and anterior cingulate and insular cortices. The hypnotic state induced a significant activation of a right-sided extrastriate area and the anterior cingulate cortex. The interaction analysis showed that the activity in the anterior (mid-)cingulate cortex was related to pain perception and unpleasantness differently in the hypnotic state than in control situations. CONCLUSIONS: Both intensity and unpleasantness of the noxious stimuli are reduced during the hypnotic state. In addition, hypnotic modulation of pain is mediated by the anterior cingulate cortex. [less ▲]

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See detailComments on the criticisms of Coquel and Abdesselam-Rouighi (1999) to the paper of Loboziak et al. (1998)
Loboziak, S; Melo; Streel, Maurice ULg

in Annales de la Société Géologique du Nord (2000), 8

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See detail5-HT2A receptor polymorphism gene in Bipolar Patients and Harm Avoidance personality trait
Blairy, Sylvie ULg; Massat, I; Staner, L et al

in American Journal of Medical Genetics Part B-Neuropsychiatric Genetics (2000), 96(3), 360-364

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See detailBasic rules of dosimetry in endovascular brachytherapy.
Coucke, Philippe ULg; PHUOC DO, Hu; Pica, Alessia et al

in Journal of Interventional Cardiology (2000), 13(6), 425-429

Endovascular brachytherapy after percutaneous coronary intervention (PCI), is becoming a standard approach for the treatment and prevention of restenosis. A variety of technical approaches are currently ... [more ▼]

Endovascular brachytherapy after percutaneous coronary intervention (PCI), is becoming a standard approach for the treatment and prevention of restenosis. A variety of technical approaches are currently available to deliver ionizing irradiation to the vascular target. Basically two kinds of radioactive isotopes are available that emit gamma radiation (photons) or beta radiation (electrons). The pitfalls and solutions for the optimization of dosimetry are discussed. As might be expected, the inhomogeneous dose distribution across the target volume results in recurrence by underdosage or in complications because of overdosage. Moreover, uniformization of the target definition and reporting of the dose distribution in endovascular brachytherapy is a prerequisite for comparison between the results of the various clinical trials and is absolutely necessary to improve the therapeutic efficacy of this new approach in the prevention of restenosis after coronary angioplasty with or without stenting. (J Interven Cardiol2000; 13:425430) [less ▲]

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See detailLaparoscopic myolysis.
Donnez, Jacques; Sqifflet, Jean; Polet, Roland et al

in Human Reproduction Update (2000), 6(6), 609-13

This review will focus on the different techniques and the long-term effects of the technique called myolysis on myoma growth. Indications for myolysis are essentially pelvic pain, compression symptoms ... [more ▼]

This review will focus on the different techniques and the long-term effects of the technique called myolysis on myoma growth. Indications for myolysis are essentially pelvic pain, compression symptoms and global uterine volume in order to avoid hysterectomy. In the late 1980s, myolysis was performed laparoscopically with the help of the neodynium: yttrium aluminium garnet (Nd:YAG) laser. Later, bipolar needles were developed as an alternative to the Nd:YAG laser. Diathermy and cryomyolysis were also proposed but series are small in the literature. Very recently, myoma interstitial thermo-therapy (MITT) was performed using the diode laser and a specific optical light diffuser that is designed to transmit laser light in all directions. Laparoscopic myolysis was proved to be effective in provoking myoma shrinkage, with a dramatic decrease in size and a marked devascularization of the myoma and this technique can be proposed as an alternative to myomectomy in selected patients: only those aged >40 years or those not desiring to bear any more children. [less ▲]

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See detailMicropore size distributions of activated carbons
Blacher, Silvia ULg; Sahouli, Bendida; Heinrichs, Benoît ULg et al

in Langmuir (2000), 16(16), 6754-6756

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See detailL'osteoporose involutive de la femme: strategie therapeutique. Un point de vue actualise du Belgian Bone Club.
Kaufman, J M; Body, J J; Boonen, S et al

in Revue Médicale de Liège (2000), 55(5), 443-8

Osteoporosis is now considered as a major public health issue and a serious threat for the quality of life of elderly women. Several new compounds are currently marketed for the prevention and treatment ... [more ▼]

Osteoporosis is now considered as a major public health issue and a serious threat for the quality of life of elderly women. Several new compounds are currently marketed for the prevention and treatment of involutional osteoporosis in women. Therefore, it is important to offer to the practitioners pragmatic solutions to be used for the rational management of this disorder. This article is the result of a national consensus offering practical guidelines for the management of osteoporotic patients, based on the current published data. [less ▲]

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See detailPhytothérapie traditionnelle des bovins dans les élevages de la plaine de la Ruzizi
Byavu, N.; Henrard, C.; Dubois, M. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(3), 135-156

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See detailClinical course and predictive factors for cyclosporin-induced autologous graft-versus-host disease after autologous haematopoietic stem cell transplantation.
Baron, Frédéric ULg; Gothot, André ULg; Salmon, Jean ULg et al

in British Journal of Haematology (2000), 111(3), 745-53

The administration of cyclosporin A (CyA) after autologous haematopoietic stem cell transplantation (HSCT) induces a systemic autoimmune syndrome mimicking graft-vs.-host disease (GVHD). This syndrome ... [more ▼]

The administration of cyclosporin A (CyA) after autologous haematopoietic stem cell transplantation (HSCT) induces a systemic autoimmune syndrome mimicking graft-vs.-host disease (GVHD). This syndrome, termed autologous GVHD has notable anti-tumour activity in animal studies. We intended to induce autologous GVHD with CyA in patients undergoing an autologous HSCT. We prospectively studied 118 patients with miscellaneous malignancies undergoing an autologous HSCT with low-dose CyA to characterize the clinical syndrome, its frequency and clinical course, and to determine the factors affecting its incidence. Patients received CyA from d -1 through to d 28, first starting at 2 mg/kg intravenously and then orally as soon as feasible. The dose was adjusted to achieve pre-dose blood levels around 100 ng/ml. A skin biopsy was performed when a skin rash was observed. Thirty-three percent of the patients developed clinical GVHD: clinical stage 1 in 21 patients, stage 2 in seven patients, and stage 3 in three patients. Although total body irradiation (TBI) or high-dose cyclophosphamide were previously thought to be needed, autologous GVHD occurred in five out of 12 patients (42%) after a preparative regimen with high-dose melphalan alone. Autologous GVHD was significantly more frequent in patients older than 33 years, in patients who had received high doses of granulocyte-macrophage colony forming units (CFU-GM) and in those with a diagnosis of myeloid malignancy, compared with those with lymphoid malignancies or solid tumours. A significant negative association was also found with HLA-DR6. In lymphoma patients, GVHD occurred more frequently in advanced disease than in first or second complete remission (CR1-2) patients. All other factors studied were not predictive for GVHD. In conclusion, CyA-induced GVHD is reproducibly and safely induced with doses of CyA adapted to achieve blood levels around 100 ng/ml. In retrospective analysis, there was no survival advantage for patients with GVHD. Phase III trials with this approach are needed to evaluate its anti-tumoral effect. [less ▲]

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See detailCharacterization of intestinal cnf1+ Escherichia coli from weaned pigs
Toth, I.; Oswald, E.; Mainil, Jacques ULg et al

in International Journal of Medical Microbiology (2000), 290

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See detailIpsilateral motor responses to focal transcranial magnetic stimulation in normal and stroke patients.
ALAGONA G.; DELVAUX, Valérie ULg; GERARD, Pascale ULg et al

in Journal of Neurology, Neurosurgery & Psychiatry (2000), Neurosurgery and Psychiatry

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See detailPhalangeal osteosonogrammetry study: age-related changes, diagnostic sensitivity, and discrimination power. The Phalangeal Osteosonogrammetry Study Group.
Wuster, C; Albanese, C; De Aloysio, D et al

in Journal of Bone and Mineral Research (2000), 15(8), 1603-14

Phalangeal osteosonogrammetry was introduced as a method for bone tissue investigation in 1992. It is based on the measure of the velocity of ultrasound (amplitude-dependent speed of sound [AD-SoS]) and ... [more ▼]

Phalangeal osteosonogrammetry was introduced as a method for bone tissue investigation in 1992. It is based on the measure of the velocity of ultrasound (amplitude-dependent speed of sound [AD-SoS]) and on the interpretation of the characteristics of the ultrasound signal. In this study we have collected a database of 10,115 subjects to evaluate the performance of AD-SoS and to develop a parameter that is able to quantify the signal characteristics: ultrasound bone profile index (UBPI). The database only includes females of which 4.5% had documented vertebral osteoporotic fractures, 16% lumbar spine dual X-ray absorptiometry (DXA), and 6% hip DXA. The analysis of the ultrasound signal has shown that with aging the UBPI, first wave amplitude (FWA), and signal dynamics (SDy) follow a trend that is different from the one observed for AD-SoS; that is, there is no increase during childhood. In the whole population, the risk of fracture per SD decrease for AD-SOS was odds ratio (OR) 1.71 (CI, 1.58-1.84). The AD-SoS in fractured subjects was significantly lower than in a group of age-matched nonfractured subjects (p < 0.0001). In a small cohort of hip-fractured patients UBPI proved to be lower than in a control age-matched group (p < 0.0001). When the World Health Organization (WHO) working group criteria were applied to this population to identify the T score value for osteoporosis, for AD-SoS we found a T score of -3.2 and for UBPI we found a T score of -3.14. Sixty-six percent of vertebral fractures were below the AD-SoS -3.2 T score and 62% were below UBPI -3.14. We observed the highest incidence of fractures (63.6%) among subjects with AD-SoS who had both DXA T score values below the threshold. We conclude from this study that ultrasound investigation at the hand phalanges is a valid methodology for osteoporosis assessment. It has been possible to quantify signal changes by means of UBPI, a parameter that will improve the possibility of investigating bone structure. [less ▲]

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See detailCritical points and reaction paths characterization on a potential energy hypersurface
Ramquet, Marie-Noëlle; Dive, Georges ULg; Dehareng, Dominique ULg

in Journal of Chemical Physics (2000), 112(11), 4923-4934

Most of the time, the definitions of minima, saddle points or more generally order p (p=0,...,n) critical points, do not mention the possibility of having zero Hessian eigenvalues. This feature reflects ... [more ▼]

Most of the time, the definitions of minima, saddle points or more generally order p (p=0,...,n) critical points, do not mention the possibility of having zero Hessian eigenvalues. This feature reflects some flatness of the potential energy hypersurface in a special eigendirection which is not often taken into account. Thus, the definitions of critical points are revisited in a more general framework within this context. The concepts of bifurcation points, branching points, and valley ridge inflection points are investigated. New definitions based on the mathematical formulation of the reaction path are given and some of their properties are outlined. (C) 2000 American Institute of Physics. [S0021-9606(00)01110-7]. [less ▲]

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See detailMolecular diversity of Microcystis strains (Cyanophyceae, Chroococcales) based on 16S rDNA sequences
LEPERE, Claire ULg; Wilmotte, Annick ULg; Meyer, Barbara

in Systematics and Geography of Plants (2000), 70

Partial 16S rDNA sequences were determined for six Microcystis strains from lakes in the region of Plön (Northern Germany) assigned to four different species on the basis of their morphology. These ... [more ▼]

Partial 16S rDNA sequences were determined for six Microcystis strains from lakes in the region of Plön (Northern Germany) assigned to four different species on the basis of their morphology. These sequences appear very similar to each other and to those of 71 Microcystis strains from four continents available in the databases. This great genotypic homogeneity, as measured by 16S rDNA sequence similarity (334 characters), is contrasting with the conspicuous morphological differences observed for the studied strains. [less ▲]

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See detailChanges in the moss layer after liming in a Norway spruce (Picea abies (L.) Karst.) stand of Eastern Belgium
Dulière, J.-F.; De Bruyn, R.; Malaisse, François ULg

in Forest Ecology & Management (2000), 136(1-3), 97-105

The impact of dolomite lime (5 t ha -1) on the moss layer was investigated in a Belgian Norway spruce (Picea abies (L.) Karst.) forest. Bryophytes reacted rapidly, showing a decrease in frequency, cover ... [more ▼]

The impact of dolomite lime (5 t ha -1) on the moss layer was investigated in a Belgian Norway spruce (Picea abies (L.) Karst.) forest. Bryophytes reacted rapidly, showing a decrease in frequency, cover and biomass of acidophilous dominant Dicranaceae species. Some neutrophilous competitive or stress tolerant species were spreading out and some ruderals appeared. The reaction of the dominant species coverage to different liming rates was also considered. Results showed that the negative effect was more pronounced than higher dolomite doses were. (C) 2000 Elsevier Science B.V. [less ▲]

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See detailLes non-recommandations dans le traitement de l'arthrose et de la polyarthrite rhumatoïde, ou pourquoi la médecine basée sur le niveau de preuve ne s'applique pas (encore) à la rhumatologie
Malaise, Michel ULg

in Revue Médicale de Liège (2000), 55(5), 466-475

The speed with which the phrase "Evidence-Based Medicine" has entered our language has been astonishing. Virtually all medical areas are concerned, but it probably applies best when clearcut diagnosis can ... [more ▼]

The speed with which the phrase "Evidence-Based Medicine" has entered our language has been astonishing. Virtually all medical areas are concerned, but it probably applies best when clearcut diagnosis can be made or when mortality or well-defined morbidity are the outcomes, two conditions not really frequently encountered in rheumatology. We will discuss why rheumatology is probably not ready yet for the concept and will systematically review why "Evidence-Based Medicine" could in fact be "evidence-biased medicine". We will emphasize why evidence-based medicine can not replace the personal experience and knowledge of patients, two major corner-stones in the clinician's daily work, but should simply be an access to scientific data for the benefit of both patient and physician. [less ▲]

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See detailVariability of Doppler ultrasound measurements of hindlimb blood flow in conscious horses
Raisis, Anthea L; Young, L. E.; Meire, H. B. et al

in Equine Veterinary Journal (2000), 32(2), 125-132

Ultrasonography of the left and right femoral artery and vein was performed in 5 conscious horses. Velocity waveforms, recorded using low pulse repetition frequency, were used to calculate time-averaged ... [more ▼]

Ultrasonography of the left and right femoral artery and vein was performed in 5 conscious horses. Velocity waveforms, recorded using low pulse repetition frequency, were used to calculate time-averaged mean velocity (TAV), velocity of component a (TaVa), velocity of component b (TaVb) and volumetric flow. Waveform analysis included calculation of early diastolic deceleration slope (EDDS) and pulsatility index (PI) and subjective description of the waveform. Measurements were recorded at monthly intervals for 6 months. The repeated measurements were used to determine the within-horse variation. Horses were then anaesthetised with halothane and the same measurements recorded 60 min after induction. Differences between measurements recorded in conscious and anaesthetised horses were determined. Within-horse variability for diameters of femoral arteries and veins was small (CV<10%). Within variability for all other measurements was marked (CV>11%), with within-horse variability being the largest for femoral venous flow (CV>35%). Source of variability was measurement error and biological variation. Despite variability in conscious horses it was possible to detect changes in blood flow during anaesthesia. In the femoral arteries, volumetric flow was lower and EDDS and PI was higher in anaesthetised horses. In the femoral veins, volumetric flow was also lower in anaesthetised horses. Therefore Doppler ultrasound appears to be a useful technique for studying blood flow in conscious and anaesthetised horses [less ▲]

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See detailIonic adsorption of ammonium and nitrate on some animal litters and their role in ammonia volatilization
Nimenya, H.; Delaunois, A.; Bloden, Serge ULg et al

in Annals of Zootechnology (2000), 49

Two experiments were carried out to determine the adsorption of ammonium and nitrate on litters (Exp. 1) and the volatilization of ammonia in their presence (Exp. 2). In Exp. 1, glass tubes containing 15 ... [more ▼]

Two experiments were carried out to determine the adsorption of ammonium and nitrate on litters (Exp. 1) and the volatilization of ammonia in their presence (Exp. 2). In Exp. 1, glass tubes containing 15 mi of a buffered solution enriched with NH4Clcalculated as 10.59 mg.l(-1) of NH4+ or KNO3 calculated as 50 mg.l(-1) of NO3- were used. Graded amounts (0 [control], 25, 50, 100 mg) of litters (wheat straw, nax straw (Equi-lin(R)), zeolite (Zeolite Stall Fresh(R)), spruce sawdust and beech sawdust) were added to the tubes which were incubated for 24 h. Ammonium and nitrate concentrations, and pH, were checked on the supernatant. A preliminary experiment was carried out with zeolite to come to an ammonium balance. After adsorption of ammoniumby graded amounts of zeolite, [0 (control), 0.25, 1, 2, 4 g], ammonium balance was assessed after two elutions with 1 N HCl. In Exp. 2, Woulff flasks were used and ammonia was trapped in a solution of 0.1 N HCl. The preliminary experiment showed that the ammonium added and adsorbed by different amounts of zeolite was completely recovered after 2 elutions. All litters, except beech sawdust, were effective in ammonium adsorption. Especially, the straws were required in very small amounts to immobilize the added ammonium or nitrate. Furthermore, with straws the pH value decreased from pH 7.5-7.60 to pH 6.90, and this effect was related to the amounts of material added. For each pH group, ammonia volatilization was significantly decreased (P <0.05) with straw (wheat straw, Equi-lino) as compared with their blank pH group. However, no significant decrease was observed with sawdust (spruce, beech) and zeolite [less ▲]

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See detailMultimedia education in headache: the European Neurological Network.
Russell, M. B.; Dremstrup Nielsen, K.; Rasmussen, C. et al

in European Journal of Neurology (2000), 7(3), 355-62

The European Neurological Network is a European Economic Community supported project. The purpose of the project was to develop a multimedia educational tool for general practitioners in order to improve ... [more ▼]

The European Neurological Network is a European Economic Community supported project. The purpose of the project was to develop a multimedia educational tool for general practitioners in order to improve their management of sleep disorders, epilepsy and headache. The project involves approximately one hundred engineers and physicians from Belgium, Denmark, England, Finland, France, Germany, Italy, Portugal and Spain. This paper concerns the multimedia educational tool on headache. The system consists of five different modules, i.e. classification, clinical data, headache tutorial, diagnostic headache diary and nomenclature. It is possible to move between the modules both vertically and horizontally. The headache classification of the International Headache Society is provided in full text as a work of reference. This classification is used world wide and has been adopted by International Classification of Diseases 10 Neurological Adaptation (ICD-10 NA) and the World Health Organisation. The clinical data concentrate on migraine and tension-type headache, the two most common headache disorders, but data on familial hemiplegic migraine, cluster headache, drug-induced headache and secondary headaches are also available. The headache tutorial consists of case records that the user can test their diagnostic abilities on. The diagnostic headache diary is an expert system on headache diagnostics. It can be filled in during a consultation in order to provide the headache diagnosis or it can be printed and used by the headache patient to record headache attacks and medicine consumption. The nomenclature module provides an explanation of words and expressions used in the system. [less ▲]

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See detailNutrient depletions in the Ross Sea and their relation with pigment stocks
Goeyens, Leo; Elskens, Marc; Catalano, Giulio et al

in Journal of Marine Systems (2000), 27

The present article depicts a first attempt to relate the governing nutrient uptake regime and phytopigment signature of the Ross Sea. Based on nutrient and phytopigment data obtained during two cruises ... [more ▼]

The present article depicts a first attempt to relate the governing nutrient uptake regime and phytopigment signature of the Ross Sea. Based on nutrient and phytopigment data obtained during two cruises in the Ross Sea, two distinct groups were recognised. The first one was characterised by moderate nutrient nitrate and silicic acid depletions in combination with relatively high diatom and Phaeocystis abundance. The second group showed very low nutrient depletions and very poor diatom abundance. Average depth specific nitrate depletions were 8.1 and 1.1 μM and average silicic acid depletions were 21.5 and 1.3 μM, respectively. The nutrient consumption patterns did not match the conditions of silicic acid excess (SEA) or nitrate excess areas (NEA), a clear trend being probably obscured by very poor seasonal maturity of several sampling stations. The contrast between both groups is largely explained by small differences in nitrogen uptake regime of the major phytoplankters. During early season, the diatoms meet the majority of their nitrogen requirements by nitrate uptake, with few exceptions where ammonium is the most important nitrogenous substrate. On average, their nitrate uptake capacity is lower than that of Phaeocystis (average specific nitrate uptake rates were 0.021 and 0.036 day y-1 for diatoms and Phaeocystis, respectively). The latter phytoplankton always shows predominance of nitrate uptake. Both groups are subject to inhibition of nitrate uptake when ammonium availability increases, and it is likely that the diatoms are more sensitive to the inhibitory effect of ammonium. [less ▲]

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See detailElectrical conduction by interface states in semiconductor heterojunctions
El Yacoubi, Mohamed; Evrard, Roger ULg; Nguyen, Ngoc Duy ULg et al

in Semiconductor Science & Technology (2000), 15

Electrical conduction in semiconductor heterojunctions containing defect states in the interface region is studied. As the classical drift-diffusion mechanism cannot in any case explain electrical ... [more ▼]

Electrical conduction in semiconductor heterojunctions containing defect states in the interface region is studied. As the classical drift-diffusion mechanism cannot in any case explain electrical conduction in semiconductor heterojunctions, tunnelling involving interface states is often considered as a possible conduction path. A theoretical treatment is made where defect states in the interface region with a continuous energy distribution are included. Electrical conduction through this defect band then allows the transit of electrons from the conduction band of one semiconductor to the valence band of the second component. The analysis is initiated by electrical measurements on n-CdS/p-CdTe heterojunctions obtained by chemical vapour deposition of CdS on (111) oriented CdTe single crystals, for which current--voltage and capacitance--frequency results are shown. The theoretical analysis is based on the numerical resolution of Poisson's equation and the continuity equations of electrons, holes and defect states, where a current component corresponding to the defect band conduction is explicitly included. Comparison with the experimental curves shows that this formalism yields an efficient tool to model the conduction process through the interface region. It also allows us to determine critical values of the physical parameters when a particular step in the conduction mechanism becomes dominant. [less ▲]

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See detailInfluence du 'sense of coherence' dans l'adaptation aux conséquences aversives du traumatisme
François, G.; Brouette, Béatrice ULg; Etienne, Anne-Marie ULg et al

in Revue Francophone de Clinique Comportementale et Cognitive (2000), V(1), 20-27

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See detailLe maillage vert... ou les réseaux de toute nature...
Mougenot, Catherine ULg; Melin, Eric ULg

in Cahiers de l'Urbanisme (Les) (2000), (28-29), 42-45

Depuis quelques années se développent un peu partout des projets de sentiers nature, de réseaux de cheminements lents, de création de mares, de jardin au naturel, etc. Ils peuvent être regroupés sous le ... [more ▼]

Depuis quelques années se développent un peu partout des projets de sentiers nature, de réseaux de cheminements lents, de création de mares, de jardin au naturel, etc. Ils peuvent être regroupés sous le terme de maillage vert ou de réseau écologique. L'article souligne que pour que de tels projets aboutissent, ils supposent une interaction étroite entre réseaux naturels et réseaux humains. [less ▲]

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See detailTracabilite dans la filiere animale.
Portetelle, Daniel ULg; Haezebroeck, V.; Mortiaux, F. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(4),

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See detailLexique des termes de physiologie et de pathologie et performances de reproduction chez les bovins
Badinand, F.; Bedouet, J.; Cosson, J. L. et al

in Annales de Médecine Vétérinaire (2000), 144

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See detailSurfactin and iturin A effects on Bacillus subtilis surface hydrophobicity.
Ahimou, F.; Jacques, Philippe ULg; Deleu, Magali ULg

in Enzyme & Microbial Technology (2000), 27(10), 749-754

The synthesis of extracellular molecules such as biosurfactants should have major consequences on bacterial adhesion. These molecules may be adsorbed on surfaces and modify their hydrophobicities. Certain ... [more ▼]

The synthesis of extracellular molecules such as biosurfactants should have major consequences on bacterial adhesion. These molecules may be adsorbed on surfaces and modify their hydrophobicities. Certain strains of Bacillus subtilis synthesize the lipopeptides, which exhibit antibiotic and surface active properties. In this study the high-performance liquid chromatography (HPLC) analysis of the culture supernatants of the seven B. subtilis strains, showed that the lipopeptide profile varied greatly according to the strain. Among the three lipopeptide types, only iturin A was produced by all B. subtilis strains. Bacterial hydrophobicity, evaluated by the water contact angle measurements and the hydrophobic interaction chromatography, varied according to the strain. Two strains (ATCC 15476 and ATCC 15811) showing extreme behaviors in term of hydrophobicity were selected to study surfactin and iturin A effects on bacterial hydrophobicity. The two lipopeptides modified the B. subtilis surface hydrophobicity. Their effects varied according to the bacterial surface hydrophobic character, the lipopeptide type and the concentration. Lipopeptide adsorption increased the hydrophobicity of the hydrophilic strain but decreased that of the hydrophobic. Comparison of lipopeptide effects on B. subtilis surface hydrophobicity showed that surfactin was more effective than iturin A for the two strains tested. [less ▲]

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See detailEffect of nicotine on rat gingival fibroblasts in vitro
Lahmouzi, Jamila ULg; Simain-Sato, Franklin ULg; Defresne, Marie-Paule ULg et al

in Connective Tissue Research (2000), 41(1), 69-80

Nicotine from 3 to 5 mM affects growth and survival rate of rat gingival fibroblasts in vitro. Ultrastructural analysis revealed dilated mitochondria and vacuolization in treated cells, suggestive of ... [more ▼]

Nicotine from 3 to 5 mM affects growth and survival rate of rat gingival fibroblasts in vitro. Ultrastructural analysis revealed dilated mitochondria and vacuolization in treated cells, suggestive of necrosis, but increased apoptosis was also revealed by cytometry. On the basis of this in vitro study, it appear that tobacco, through its component nicotine, may directly affect various functions of rat gingival fibroblasts [less ▲]

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See detailArtifact-tolerant controllers for automatic drug delivery in anesthesia
Frei, Christian W; Bullinger, Eric ULg; Gentilini, Andrea et al

in Critical Reviews in Biomedical Engineering (2000), 28(1-2), 187-192

This article presents a method for treating measurement artifacts in model-based control systems. A nonlinear modification to the usual observer structure is introduced to prevent the measurement ... [more ▼]

This article presents a method for treating measurement artifacts in model-based control systems. A nonlinear modification to the usual observer structure is introduced to prevent the measurement artifacts from winding up the controller states. It is shown how stability of the closed loop system can he analyzed and an example of a successful application in a clinical study is provided. [less ▲]

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See detail"note sous J.P. Jumet, 24 février 2000"
Moreau, Pierre ULg

in Actualités du Droit (2000)

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See detailEpithelial and endothelial expression of the green fluorescent protein reporter gene under the control of bovine prion protein (PrP) gene regulatory sequences in transgenic mice.
Lemaire-Vieille, C.; Schulze, T.; Podevin-Dimster, V. et al

in Proceedings of the National Academy of Sciences of the United States of America (2000), 97(10), 5422-7

The expression of the cellular form of the prion protein (PrP(c)) gene is required for prion replication and neuroinvasion in transmissible spongiform encephalopathies. The identification of the cell ... [more ▼]

The expression of the cellular form of the prion protein (PrP(c)) gene is required for prion replication and neuroinvasion in transmissible spongiform encephalopathies. The identification of the cell types expressing PrP(c) is necessary to understanding how the agent replicates and spreads from peripheral sites to the central nervous system. To determine the nature of the cell types expressing PrP(c), a green fluorescent protein reporter gene was expressed in transgenic mice under the control of 6.9 kb of the bovine PrP gene regulatory sequences. It was shown that the bovine PrP gene is expressed as two populations of mRNA differing by alternative splicing of one 115-bp 5' untranslated exon in 17 different bovine tissues. The analysis of transgenic mice showed reporter gene expression in some cells that have been identified as expressing PrP, such as cerebellar Purkinje cells, lymphocytes, and keratinocytes. In addition, expression of green fluorescent protein was observed in the plexus of the enteric nervous system and in a restricted subset of cells not yet clearly identified as expressing PrP: the epithelial cells of the thymic medullary and the endothelial cells of both the mucosal capillaries of the intestine and the renal capillaries. These data provide valuable information on the distribution of PrP(c) at the cellular level and argue for roles of the epithelial and endothelial cells in the spread of infection from the periphery to the brain. Moreover, the transgenic mice described in this paper provide a model that will allow for the study of the transcriptional activity of the PrP gene promoter in response to scrapie infection. [less ▲]

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See detailClinical impact and perspectives of 18F-FDG PET in lymphoma
Jerusalem, Guy ULg; Beguin, Yves ULg

in Clinical Lymphoma (2000), 1

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See detailUn outil d’optimisation des structures orthotropes intégré à l’avant-projet
Rigo, Philippe ULg

in Construction Métallique (2000)

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See detailComparison of rectal and infrared ear temperatures in older hospital inpatients.
Smitz, Simon ULg; Giagoultsis, T; Dewé, Walthère ULg et al

in Journal of the American Geriatrics Society (2000), 48(1), 63-6

OBJECTIVES: To assess the agreement between infrared emission detection (IRED) ear and rectal temperatures and to determine the validity of IRED ear thermometry in detecting rectal fever. DESIGN ... [more ▼]

OBJECTIVES: To assess the agreement between infrared emission detection (IRED) ear and rectal temperatures and to determine the validity of IRED ear thermometry in detecting rectal fever. DESIGN: Prospective, convenience sample, unblinded study. SETTING: An acute geriatric unit (teaching hospital) and a multidisciplinary intensive care unit. PARTICIPANTS: The study included 45 inpatients (26 women and 19 men), aged 78.3+/-6.9 years, admitted over a 4-month period. Twelve of the patients were definitely infected. MEASUREMENTS: Sequential rectal (RT) and ear temperature (ET) measurements were performed using mercury-in-glass and IRED ear thermometers, respectively. IRED ear temperatures were measured at both ears (unadjusted mode), with the highest of six ear temperatures considered the true value. RESULTS: Mean RT (37.39 degrees C +/- 0.52 degrees C) was significantly (P<.001) higher than mean ET (36.89 degrees C +/-0.59 degrees C). A highly significant positive correlation was found between RT and ET (slope = 0.69; 95% CI, 0.52-0.86; P<.001; r = 0.78). The mean bias (mean of the differences) between RT and ET was 0.50 degrees C +/-0.37 degrees C (95% CI, 0.41 degrees C-0.59 degrees C), and the 95% limits of agreement -0.22 degrees C and 1.23 degrees C (95% CI, -0.38 degrees C to 1.39 degrees C). According to the standard criterion (RT > or =37.6 degrees C), 14 patients were febrile. Using an optimum IRED ear fever threshold (37.2 degrees C), the sensitivity and specificity of IRED ear thermometry for predicting rectal fever were 86% and 89%, respectively (positive predictive value, 80%; negative predictive value, 93%). CONCLUSIONS: The degree of agreement between rectal temperature and the highest of six IRED ear temperatures was acceptable. Using an optimal IRED ear fever threshold of 37.2 degrees C (99 degrees F), IRED ear thermometry had acceptable sensitivity and specificity for predicting rectal fever. [less ▲]

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See detailDependency of Premature Ventricular Contractions on Heart Rate and Circadian Rhythms During Childhood
Massin, M. M.; Maeyns, K.; Withofs, Nadia ULg et al

in Cardiology (2000), 93(1-2), 70-3

The aim of the present study was to identify and quantify the rate dependence of premature ventricular contractions (PVC) during childhood. A 24-hour Holter recording was performed in 16 consecutive ... [more ▼]

The aim of the present study was to identify and quantify the rate dependence of premature ventricular contractions (PVC) during childhood. A 24-hour Holter recording was performed in 16 consecutive children, aged 22 days to 11 years (mean age 5.6 years), with frequent (>5,000/day), isolated monomorphic PVC. Those PVC were identified and the length of the preceding sinus cycle was measured. The values were ordered into 50-ms class intervals, and the percentage of PVC for each class was calculated and then analyzed by linear regression analysis. On the basis of the significance of the p value, and the positive or negative value of the slope, we identified a tachycardia-enhanced, a bradycardia-enhanced, and an indifferent pattern. Chronobiologic analysis was made by the cosinor method. All the patients had upper and lower limits of cycle length beyond which PVC disappeared. A tachycardia-enhanced pattern was present in 7 patients and an indifferent one in 9 patients. In the latter a second-degree polynomial correlation was systematically found. Children but not infants had a significant circadian variation in the frequency of PVC with a very variable time of highest incidence. In conclusion, it is possible to identify a circadian rhythm of PVC and a spontaneous trend between their incidence and the length of the preceding cardiac cycle in children. [less ▲]

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See detailExpression of receptors for insulin-like growth factor-I and transforming growth factor-beta in human follicles.
Qu, Jian Ping; GODIN, Pierre-Arnaud ULg; NISOLLE, Michelle ULg et al

in Molecular Human Reproduction (2000), 6(2), 137-45

The in-vitro growth of immature oocytes in early follicles from cryopreserved human ovarian tissues is a new concept in in-vitro fertilization programmes for the treatment of infertile and cancer patients ... [more ▼]

The in-vitro growth of immature oocytes in early follicles from cryopreserved human ovarian tissues is a new concept in in-vitro fertilization programmes for the treatment of infertile and cancer patients. To better understand the regulatory mechanism of follicular development, immunohistochemistry was used to study the expression of insulin-like growth factor (IGF) type I receptor (IGF-IR) and transforming growth factor-β (TGFβ) type I (TβR-I) and type II (TβR-II) receptors in fresh and frozen ovarian tissues from 14 women. Immunoreactivities for IGF-IR and TβR-I were present simultaneously in the oocytes of primordial, pre-antral and antral follicles. Staining for both IGF-IR and TβR-I was also observed in granulosa cells of primordial, pre-antral and antral follicles. IGF-IR and TβR-I also stained in thecal cells of pre-antral and antral follicles. Stromal cells in surrounding ovarian tissue expressed IGF-IR and TβR-I at various follicular stages. Unlike TβR-I, TβR-II was expressed only in the oocytes of primordial and primary follicles, and with weak staining intensity in thecal cells. No significant staining for TβR-II was found in oocytes and granulosa cells of antral follicles. There was no difference in staining patterns for IGF-IR, TβR-I and TβR-II between fresh and frozen ovarian tissues, indicating that cryopreservation might not significantly alter the immunoreactivities of these receptors in frozen ovarian tissue. The results suggest that IGF-I and TGFβ may participate in the regulation of follicular growth by binding to their receptors through an autocrine or paracrine mechanism. IGF-I and TGFβ may be useful in regulating the in-vitro or in-vivo maturation of oocytes not only in later follicles but also very early follicles, from cryopreserved ovarian tissues for clinical use in the future. [less ▲]

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See detailComment j'explore ... un cancer broncho-pulmonaire par imagerie metabolique (TEP-18-FDG).
Bury, Thierry ULg; DUYSINX, Bernard ULg; CORHAY, Jean-Louis ULg et al

in Revue Médicale de Liège (2000), 55(3), 178-83

Continuing advances in PET imaging have resulted in an improved ability to evaluate thoracic malignancies. Published reports demonstrate that PET provides accurate noninvasive detection of malignancy that ... [more ▼]

Continuing advances in PET imaging have resulted in an improved ability to evaluate thoracic malignancies. Published reports demonstrate that PET provides accurate noninvasive detection of malignancy that is useful in the characterization of a pulmonary solitary nodule and in the mediastinal or extrathoracic staging of known lung cancer. Preliminary studies suggest that PET may also be able to assess the therapeutic response after surgery or radiation therapy. [less ▲]

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See detailEffect of gonadal steroids on pituitary LH secretion and mediobasal hypothalamic GnRH mRNA in ferrets.
Bakker, Julie ULg; Baum, M. J.

in Journal of Reproduction and Fertility (2000), 119(2), 315-21

In vitro release and content of GnRH in mediobasal hypothalamic slices are reduced by ovariectomy of female ferrets but are not affected by castration of male ferrets in breeding condition. The aim of the ... [more ▼]

In vitro release and content of GnRH in mediobasal hypothalamic slices are reduced by ovariectomy of female ferrets but are not affected by castration of male ferrets in breeding condition. The aim of the present study was to determine whether this sex difference reflects a sexually dimorphic effect of gonadal steroids on mediobasal hypothalamic GnRH mRNA content of male and female ferrets killed 4 weeks after gonadectomy, either with or without steroid hormone replacement. This time interval exceeds the 6-10 days needed for increments in plasma LH concentrations to stabilize after gonadectomy of ferrets of both sexes. In situ hybridization using an (35)S-labelled oligoprobe complementary to the human GnRH coding region showed that the number of mediobasal hypothalamic neurones and the cellular content of GnRH mRNA did not differ significantly among groups of male and female ferrets that were either in breeding condition or that had been gonadectomized and treated with sex steroids or oil vehicle. These results indicate that gonadal hormones regulate mediobasal hypothalamic GnRH biosynthesis and release in both sexes via post-transcriptional events that may include GnRH mRNA translation or the conversion of pre-pro GnRH precursor into mature GnRH. [less ▲]

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See detailPreliminary survey of the palynological content of the Lower Devonian in the Oesling, Luxembourg
Steemans, Philippe ULg; Debbaut, Vincent ULg; Faber, A.

in Bulletin de la Société des Naturalistes Luxembourgeois (2000), 100

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See detailStructure-activity relationships on adrenoceptors and imidazoline-preferring binding sites (I(1,2)-PBSs). Part 1: Weak intramolecular H-bond and conformational flexibility in a new I1-PBS-selective imidazoline analogue, trans1-(4',5'-dihydro-1'H-imidazol-2'-yl)methyl-2-hydroxyindane (PMS 952).
Ye, Hai Fen; Dive, Georges ULg; Dehareng, Dominique ULg et al

in Bioorganic & Medicinal Chemistry (2000), 8(8), 1861-9

The highly selective I1-PBS imidazoline analogue PMS 952 has been selected to study the incidence of intramolecular hydrogen bond and molecular flexibility on its biological activity. On one hand, the ... [more ▼]

The highly selective I1-PBS imidazoline analogue PMS 952 has been selected to study the incidence of intramolecular hydrogen bond and molecular flexibility on its biological activity. On one hand, the weak energy difference between three calculated conformers does not support the stabilization of one conformer by an internal hydrogen bond. The 3-D electrostatic map confirms this feature and the solvent effect does not significantly modify the relative energy of these conformers. On the other hand, the conformational spaces of the neutral and ionized forms present a great number of equilibrium structures, in a short energetic range (20 Kcal). The results are representative of an exceptional conformational flexibility due to a cooperative effect between several parts of the molecule. [less ▲]

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See detailRe-entrant Peierls distortion in IV-VI compounds
Raty, Jean-Yves ULg; Gaspard, Jean-Pierre ULg; Bichara, C. et al

in Physica B: Condensed Matter (2000), 276-278

At room temperature, the local structure of crystalline group V elements (As, Sb,middotmiddotmiddot) and their IV-VI isoelectronic compounds (GeSe,middotmiddotmiddot) is governed by a Peierls distortion ... [more ▼]

At room temperature, the local structure of crystalline group V elements (As, Sb,middotmiddotmiddot) and their IV-VI isoelectronic compounds (GeSe,middotmiddotmiddot) is governed by a Peierls distortion of the simple cubic or NaCl structure which is a symmetry breaking electronic instability. The morphology of the distortion is determined by the filling ratio of the p-band; for a half-filled p-band, the sixfold coordination becomes 3 (short, covalent) +3 (long, van der Waals). In general, at high temperature, the structure recovers its higher coordination number. Neutron diffraction experiments have been made in the liquid state at lambda=0.7 Aring. It is observed that the Peierls distortion is still present in the liquid for most IV-VI compounds. This behavior is observed and discussed for a series of Sn and Ge chalcogenides: SnS, SnSe, GeS, GeSe and GeTe and their temperature evolution is discussed. GeSe and GeTe show an interesting re-entrant phase behavior. The heaviest IV-VI compound SnTe does not show a distorted state. We demonstrate that the hardness of the repulsive potential is a key parameter in this mechanism [less ▲]

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See detailL’internationalisation des entreprises de distribution. Quelques observations au départ du cas européen
Merenne-Schoumaker, Bernadette ULg

in Géographies. Bulletin de l'Association de Géographes Français (2000), (2000-1), 66-73

To understand the internationalization of retailing, we must understand the internationalization of its entreprises. With this aim in view, one first case is chosen - Europa - and the processus is learned ... [more ▼]

To understand the internationalization of retailing, we must understand the internationalization of its entreprises. With this aim in view, one first case is chosen - Europa - and the processus is learned through the main questions of geography : what where ? which evolution ? who ? how ? why and why there and not elsewhere ? The lead of territory in the strategies and the choices of the firms is clearly showed; this fact confirms the geographical relevance of the thema « Globalization of Retailing ». [less ▲]

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See detailSynthesis and evaluation of new RuCl2(p-cymene)(ER2R') and (eta(1):eta(6)-phosphinoarene)RuCl2 complexes as ring-opening metathesis polymerization catalysts
Jan, Dominique; Delaude, Lionel ULg; Simal, François et al

in Journal of Organometallic Chemistry (2000), 606(1), 55-64

New RuCl2(p-cymene)(ER2R') complexes (E = P, As, Sb; R, R' = H, alkyl, arylalkyl) have been synthesized and used as catalyst precursors for the ring-opening metathesis polymerization (ROMP) of cyclooctene ... [more ▼]

New RuCl2(p-cymene)(ER2R') complexes (E = P, As, Sb; R, R' = H, alkyl, arylalkyl) have been synthesized and used as catalyst precursors for the ring-opening metathesis polymerization (ROMP) of cyclooctene, cyclopentene, and norbornene. When ER2R' was a phosphinoarene, the p-cymene ligand could be displaced upon heating and tethered (eta(1):eta(6)-phosphinoarene)RuCl2 complexes were obtained. Simple thermogravimetric analysis (TGA) of the complexes provided clear-cut indication on their potential catalytic activity in ROMP. (C) 2000 Elsevier Science S.A. All rights reserved. [less ▲]

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See detailNekrotoxikus Escherichia coli (NTEC) törzsek magyarorszagi elöfordulasa és jellemzése
Nagy, B.; Toth, I.; Mainil, Jacques ULg et al

in Magyar Allatorvosok Lapja = Hungarian Veterinary Journal (2000), 122

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See detailFactors controlling the distribution of diatoms and Phaeocystis in the Ross Sea
Goffart, Anne ULg; Catalano, Guilio; Hecq, Jean-Henri ULg

in Journal of Marine Systems (2000), 27

The spatial and temporal distributions of phytoplankton pigments were investigated in the western and south central Ross Sea during austral spring 1994 and summer 1990. Large gradients in biomass and ... [more ▼]

The spatial and temporal distributions of phytoplankton pigments were investigated in the western and south central Ross Sea during austral spring 1994 and summer 1990. Large gradients in biomass and phytoplankton community composition were observed both in the east-west and south-north directions, in relation to differences in water column structure and stability, which themselves depend on the processes of ice retreat within the different areas. Important are melting in the western Ross Sea, which induces strong stratification, and ice breakup and wind stress in the south central Ross Sea, which result in deep mixing and weakly stratified waters. In the western Ross Sea, the highest chl a concentrations observed in this study (129 - 358 mg m-2 in the upper 100 m) were tightly coupled to the stratified region of meltwater influence and were dominated by diatoms, as indicated by elevated fucoxanthin concentrations (89 - 239 mg m-2 in the upper 100 m). In the diatom bloom area, high levels of phaeophorbides a (maximum value of 192 mg . m-2 in the upper 100 m) indicated that the dominant grazers, identified as Limacina helecina and copepods (Hecq et al., 1992), transferred a sustained part of the diatom production to the herbivore trophic level. Synthesis of our data with published information suggests that the diatom bloom we observed in the western Ross Sea was dominated by the species Fragilariopsis curta, and occurs annually off the coast of Victoria Land from 72°30'S to 77°S within 100 to 250 km from the coastal ice edge. It is assumed to persist on the order of 2.5 - 3 months during summer. In the south central Ross Sea, which was characterized by a poorly or unstratified water column, moderate chl a concentrations (55 - 186 mg m-2 in the upper 100 m) were found in the polynya and in the ice edge area in early spring. 19'-hexanoyloxyfucoxanthin, a biomarker for Phaeocystis, was the major contributor to the total carotenoid abundance (29 - 132 mg m-2 in the upper 100 m), corroborating the hypothesis that Phaeocystis are well adapted to develop in a relatively mixed water column. At the northern limit of the polynya, a quite narrow (c. a. 30 km) diatom bloom (31 - 67 mg fucoxanthin m-2 in the upper 100 m) overlapped with the Phaeocystis bloom in the slightly stratified marginal ice zone. This was an area of increased grazing pressure by various types of herbivorous zooplankton, among which very large amounts of krill were observed. [less ▲]

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See detailHipóteses estatísticas : revendo idéias sobre ortogonalidade e balanceamento em análise de varîancia
Iemma, Antonio Francisco; Claustriaux, Jean-Jacques ULg; Palm, Rodolphe ULg

in Multiciência (2000), 4(1), 62-82

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See detailWhat do the needles, syringes, lancets and reagent strips of diabetic patients become in the absence of a common attitude? About 1070 questionnaires in diabetic clinics.
Bouhanick, B.; Hadjadj, S.; Weekers, Laurent ULg

in Diabètes & Métabolism (2000), 26(4), 288-93

The aim was to investigate the fate of injection and monitoring material after its use by diabetic patients in different countries (France, Belgium, Luxemburg, Switzeland and Tunisia). Some suitable ... [more ▼]

The aim was to investigate the fate of injection and monitoring material after its use by diabetic patients in different countries (France, Belgium, Luxemburg, Switzeland and Tunisia). Some suitable containers are available for disposal but little is known about the attitudes of patients and physicians to them. 1 070 questionnaires were completed by patients (age: 50 +/- 18 years; diabetes duration: 15 +/- 11 years; 2.8 +/- 1.1 injections per day) visiting 109 doctors. Injections were done at home (72.6%), or both at home and at work (26.6%). At home: needles, syringes, lancets and reagent strips were thrown directly into the bin in 46.9%, 49.9%, 52.2% and 67.6% of cases, respectively; and in a closed plastic bottle in 29. 6%, 28.5%, 28.9% and 19.9% of cases, respectively. Specific containers were used in 8.6% and 6.3% of cases for needles and syringes, respectively. 62% of the bottles and containers were thrown directly into the bin, whereas 15.5% were returned to a pharmacy (4.5% taken to hospitals, 2.9% were burned). At work: 63% of the patients brought their needles and syringes home for disposal, 6.9% kept suitable containers at work and 30% threw their materials directly into local bins. We conclude that awareness should be increased and the organization of the collection of used material improved. [less ▲]

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See detailAffections cardiaques et intolérances à l'effort. 1-Les troubles du rythme.
Amory, Hélène ULg; Art, Tatiana ULg

in Pratique Vétérinaire Equine (2000), 32(Numéro Spécial), 71-78

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See detailPédophilie : un synopsis clinique
Kempeneers, Philippe ULg

in Sexologies (2000), 9(33), 8-17

Conceiving pedophilic sexuality as a sexuality resulting from a fack of grtifying relationships to adults is an important operational reference for the clinician. In this way, the obstacles to sexual ... [more ▼]

Conceiving pedophilic sexuality as a sexuality resulting from a fack of grtifying relationships to adults is an important operational reference for the clinician. In this way, the obstacles to sexual satisfaction with adults can become the privileged target of therapeutic and preventive acts.The narcissic fragility is certainly an obstacle common to almost all the pedophilic patterns. Beyond this common denominator, the individual cases are characterized by strong dissimilarities. The variety of the cases justifies the attempts to classify the different types of pedophiles. But the typological systems are also quite different, depending on the theorical and methodological preferences of their authors. Starting from the ideas of several authors, this article try to sum up the variety of pedophilic functioning in four axes of variation. At last, the article stresses the imortance of contexts of life as factors leading a predisposed personality to transgression [less ▲]

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See detailSystematic study and stratigraphic correlation of the Grandispora complex in the Famennian of Northwest and Eastern Europe
Higgs, K.T.; Avkhimovitch, V.I.; Loboziak, S. et al

in Review of Palaeobotany and Palynology (2000), 112

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See detailL'herpèsvirus bovin de type 4 : virus pathogène ou passager?
Thiry, Etienne ULg; Markine-Goriaynoff, Nicolas; Minner, Frédéric et al

in Point Vétérinaire (2000), 31

Bovine herpesvirus type 4 (BHV-4) is a ubiquitous herpesvirus in cattle. It has been isolated from animals showing a wide variety of clinical signs but few of the isolates have proven experimental ... [more ▼]

Bovine herpesvirus type 4 (BHV-4) is a ubiquitous herpesvirus in cattle. It has been isolated from animals showing a wide variety of clinical signs but few of the isolates have proven experimental pathogenicity. Species that are susceptible to BHV-4 include animals other than ruminants, notably cats and, surprisingly, a primate the owl monkey (Aotus trivirgatus). BHV-4 exists as a latent infection in mononuclear cells. In cattle, BHV-4 has been isolated in animals exhibiting ocular and respiratory conditions and it has been found in females with genital tract conditions such as post-partum metritis and vulvovaginitis. There is some epidemiological and experimental evidence that BHV-4 may be a cause of bovine abortion. There is no vaccine available in Europe and prevention is exclusively by hygiene measures. [less ▲]

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See detailObs. sous Cass., 8 avril 1999
Delnoy, Michel ULg

in Aménagement - Environnement (2000), 2

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See detailThe Optimisation Of The Helix/Helix Interaction Of A Transmembrane Dimer Is Improved By The Impala Restraint Field
Ducarme, P.; Thomas, Annick ULg; Brasseur, Robert ULg

in Biochimica et Biophysica Acta-Biomembranes (2000), 1509(1-2), 148-54

A continuous membrane model (IMPALA) was previously developed to predict how hydrophobic spans of proteins insert in membranes (Mol. Mod. 2 (1996) 27). Using that membrane model, we looked for the ... [more ▼]

A continuous membrane model (IMPALA) was previously developed to predict how hydrophobic spans of proteins insert in membranes (Mol. Mod. 2 (1996) 27). Using that membrane model, we looked for the interactions between several hydrophobic spans. We used the glycophorin A dimer as an archetype of polytopic protein to validate the approach. We find that the native complex do not dislocate when it is submitted to a 10(5) steps optimisation whereas separated spans converge back to a native-like complex in the same conditions. We also observe that IMPALA restraints are not strictly mandatory but do increase the efficiency of the procedure. [less ▲]

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See detailGuerres au Congo (1996-1999), acteurs et scénarios
Kabamba, Bob ULg

in cahiers du CEDAF (2000)

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See detailLes acteurs d'un système de justice pénale européen
Flore, Daniel ULg

in L’espace judiciaire pénal européen après Tampere (2000)

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See detailMeasurements of hindlimb blood flow recorded using Doppler ultrasound during administration of vasoactive agents in halothane-anesthetized horses
Raisis, Anthea L; Young, Lesley E; Meire, Hylton B et al

in Veterinary Radiology & Ultrasound : The Official Journal of the American College of Veterinary Radiology & the International Veterinary Radiology Association (2000), 41(1), 64-72

The purpose of the study was to determine the ability of Doppler ultrasound to detect changes in femoral blood flow during pharmacologic manipulation of arterial blood pressure. Doppler ultrasonography ... [more ▼]

The purpose of the study was to determine the ability of Doppler ultrasound to detect changes in femoral blood flow during pharmacologic manipulation of arterial blood pressure. Doppler ultrasonography was performed in the femoral vessels of six halothane-anesthetized horses before and during administration of phenylephrine HCI and sodium nitroprusside. The time-averaged mean velocity and volumetric flow were calculated. The contour of the velocity waveform was assessed, and the early diastolic deceleration slope (EDDS) and pulsatility index (PI) were calculated. Administration of phenylephrine HCI resulted in increased mean aortic blood pressure (MABP) by 40% (29.3-53.0%). This caused significant decrease in cardiac output (26.8 to 13.5 l/min), femoral arterial velocity (left artery 7.20 to 4.00 cm/s; right artery 5.01 to 3.39 cm/s) and volumetric flow (left artery 556 to 221 ml/min; right artery 397 to 193 ml/min) in the femoral vessels and significant increase in systemic vascular resistance (163 to 433 dyn-s/cm5), EDDS (1a: 285 to 468: ra: 250 to 481) and PI (1a: 9.38 to 20.4; ra 17.1 to 29.1). Administration of sodium nitroprusside resulted in a decreased MABP of 27.2% (22.5-33%). This increased cardiac output (20.8 to 32.4 L/min), however, no significant changes were observed in femoral blood flow. Despite obvious changes in the waveform contour, no significant change occurred in EDDS or PI. These results suggest that Doppler ultrasound may be useful for measuring femoral blood flow in anesthetized horses. However, waveform analysis appears to be limited when multiple changes occur in central and peripheral haemodynamics. [less ▲]

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See detailThe effect of PIT tags on growth and physiology of age-0 cultured Eurasian perch Perca fluviatilis of variable size
Baras, E.; Malbrouck, C.; Houbart, M. et al

in Aquaculture (2000), 185

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See detailAssessment of postoperative nausea using a visual analogue scale.
Boogaerts, J G; Vanacker, E; Seidel, Laurence ULg et al

in Acta Anaesthesiologica Scandinavica (2000), 44(4), 470-4

BACKGROUND: Assessment of postoperative nausea intensity is difficult because nausea is a subjective and unpleasant sensation. We propose using the Visual Analogue Scale (VAS) device to increase the ... [more ▼]

BACKGROUND: Assessment of postoperative nausea intensity is difficult because nausea is a subjective and unpleasant sensation. We propose using the Visual Analogue Scale (VAS) device to increase the efficiency and precision in the assessment of nausea. We carried out a pilot study on postoperative patients suffering from nausea to measure the degree of agreement between the VAS scores and those given on a 4-point verbal descriptive scale (VDS). METHODS: Postoperative nausea was evaluated by means of a classical VAS (0-10 cm) device and a 4-point VDS (0=no nausea, 1=mild, 2=moderate, 3=severe) in 128 surgical spontaneously complaining patients. Evaluation was repeated 45 min after rescue medication given if nausea was intractable, lasted more than 10 min or at the request of the patient. Ordinal logistic regression was used to measure the association between VAS and VDS and to determine cut-off points on the VAS. RESULTS: The VAS device was easily understood and used by patients. VAS scores decreased significantly from 5.5+/-2.3 to 1.4+/-1.8 after rescue medication (P=0.002). Application of ordinal logistic regression to pre- and post-medication data combined yielded an agreement of 86% between VAS and VDS and the cut-off points on the VAS were estimated as follows: 0-1 (no nausea), 1+/-4 (mild), 4+/-7 (moderate) and 7+/-10 (severe). CONCLUSION: The VAS method proved to be useful for assessing quantitative nausea intensity and for testing the efficacy of rescue medication. It was found that a cut-off value of 4 on the VAS may be considered as a critical threshold triggering anaesthesiologists or nurses to administer rescue medication. [less ▲]

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See detailSpecific phosphorylation of Torpedo 43 rapsyn by endogenous kinase(s) with thiamine triphosphate as the phosphate donor
Nghiêm, Hoang O; Bettendorff, Lucien ULg; Changeux, Jean-Pierre

in FASEB Journal (2000), 14

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