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See detailDimensionless critical shear stress evaluation from flume experiments using different gravel beds
Petit, François ULg

in Earth Surface Processes & Landforms (1994)

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See detailGeometric control of a pyridoxal-catalyzed aldol condensation
Koh, John T.; Delaude, Lionel ULg; Breslow, Ronald

in Journal of the American Chemical Society (1994), 116(25), 11234-11240

A chiral cyclophane derivative of pyridoxal has been synthesized that has amino groups oriented specifically over one face of the cofactor. The compound catalyzes the formation of threonine and allo ... [more ▼]

A chiral cyclophane derivative of pyridoxal has been synthesized that has amino groups oriented specifically over one face of the cofactor. The compound catalyzes the formation of threonine and allo-threonine from glycine and acetaldehyde with enantioinductions that are a function of pH, reversing the optical selectivity between low pH and high pH. The stereochemical results are compared with those of structurally related pyridoxal cyclophanes that lack titratable catalytic groups. Explanations are advanced for this stereochemical reversal and for the otherwise surprising preference of most of these compounds to react on the more hindered face of the pyridoxal. Models indicate that the transamination intermediate is distorted by the transannular chain, and stereoelectronic arguments predict that this distortion should lead to reaction on the face that carries the chain, as observed. The stereochemical reversal with the attached (dimethylamino)alkyl group, as a function of pH, may reflect catalysis by the protonated form, but metal coordination by the basic form cannot be excluded. [less ▲]

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See detailVers une théorie générale du signe
Badir, Sémir ULg

in Degrés : Revue de Synthèses à Orientation Sémiologique (1994), 79-80

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See detailKibaran A-type granitoids and mafic rocks generated by two mantle sources in a late orogenic setting (Burundi)
Tack, Luc; Liégeois, Jean-Paul ULg; Deblond, André et al

in Precambrian Research (1994), 68

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See detailIGF-I and IGFBP-3 increase independently of testosterone release during the onset of puberty in cattle
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

in Growth Regulation (1994), 4(suppl 1), 116

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See detailMultiple muscarinic receptor subtypes mediating pulmonary oedema in the rabbit.
Delaunois, Annie ULg; Gustin, Pascal ULg; Ansay, Michel ULg

in Pulmonary Pharmacology (1994), 7(3), 185-93

The effects of various muscarinic antagonists on acetylcholine (ACh)-induced pulmonary oedema were studied in isolated perfused rabbit lungs. ACh induced a dose-dependent increase in the capillary ... [more ▼]

The effects of various muscarinic antagonists on acetylcholine (ACh)-induced pulmonary oedema were studied in isolated perfused rabbit lungs. ACh induced a dose-dependent increase in the capillary filtration coefficient (Kf,c). This effect has been previously related to the activation of the capsaicin-sensitive nerve fibres and the release of substance P. Atropine, pirenzepine (M1-selective antagonist) and 4-DAMP (M3-selective antagonist) altered this response, producing a dose-dependent shift to the right of the ACh concentration-Kf,c response curve. By contrast, the M2-selective antagonist AFDX-116 shifted the ACh concentration-response curve to the left. Atropine, pirenzepine and 4-DAMP also significantly reduced the capsaicin-induced increase in the Kf,c, while AFDX-116 enhanced it. We conclude that multiple muscarinic receptor subtypes are present in the rabbit lung, located on the C-fibres, and are involved in the ACh-induced pulmonary oedema. M1 and M3 receptors seem to stimulate the release of neuropeptides from C-fibres, whereas M2 receptors have an inhibitory effect on these fibers. [less ▲]

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See detailThe Perturbed Tikhonov's Algorithm and Some of its Applications
Tossings, Patricia ULg

in RAIRO : Modélisation Mathématique et Analyse Numérique (Mathematical Modelling and Numerical Analysis) (1994), 28(2), 189-221

The proximal point algorithm has known these last years many developments connected with the expansion of the variational convergence theory. Motivated by this fact and inspired by the work of A. Tikhonov ... [more ▼]

The proximal point algorithm has known these last years many developments connected with the expansion of the variational convergence theory. Motivated by this fact and inspired by the work of A. Tikhonov and V. Arsénine in the context of convex optimization, we present a new algorithm for searching a zero of a maximal monotone operator on a real Hilbert space. We study the perturbed version of this algorithm and establish a critical comparison with the perturbed proximal point algorithm. We apply this new algorithm to convex optimization and to variational inclusions or, more particularly, to variational inequalities. [less ▲]

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See detailCo-movements and dynamic interrelationships in pacific basin stock markets
Corhay, Albert ULg; Tourani-Rad, Alireza; Urbain, Jean-Pierre ULg

in Research in International Business and Finance (1994), 11B

In this paper, we investigate dynamic interrelationships among the stock markets of Australia, Hong Kong, Japan, New Zealand and Singapore. Using cointegration analysis and the Granger causality test we ... [more ▼]

In this paper, we investigate dynamic interrelationships among the stock markets of Australia, Hong Kong, Japan, New Zealand and Singapore. Using cointegration analysis and the Granger causality test we find that, although the five stock price indices share some common trends, the only stock price which does not apparently Granger cause (precede) the remaining stock prices is that of New Zealand. It is further observed that all price indices are caused by the remaining stock prices except that of Australia. With respect to the geographical separation, it appears that when we consider the Asian countries as an entity and those of the Pacific as another entity, they seem not to influence each other significantly. [less ▲]

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See detailChromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers
Cockett, N. E.; Jackson, S. P.; Shay, T. D. et al

in Proceedings of the National Academy of Sciences of the United States of America (1994), 91

A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic sheep (Ovis aries). Preliminary results indicate that an autosomal ... [more ▼]

A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic sheep (Ovis aries). Preliminary results indicate that an autosomal dominant gene may be responsible for this economically advantageous trait. We have exploited the conservation in sequence and chromosomal location of DNA markers across Bovidae to map the corresponding callipyge locus to ovine chromosome 18 using a battery of bovine chromosome 21 markers. Chromosomal localization of the ovine callipyge locus is the first step toward positional cloning of the corresponding gene. [less ▲]

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See detailA Partial Approach To Model Checking
Godefroid, Patrice; Wolper, Pierre ULg

in Information & Computation (1994), 110(2), 305--326

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See detailApprendre, ou se mettre en projet ? Réflexions au départ d'une expérience de pédagogie du projet en classe du secondaire
Jadoulle, Jean-Louis ULg

in Histoire et Enseignement : Bulletin (1994), 44e année(n°1), 5-17

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See detailEffect of the emulsion stability on the morphology and porosity of semicrystalline poly-L-lactide micriparticles prepared by w/o/w double emulsion-evaporation
Schugens, Ch; Laruelle, N; Nihant, N et al

in Journal of Controlled Release (1994), 32

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See detailThe Moorcock / Hawkwind Connection: Science Fiction and Rock & Roll Culture
Delville, Michel ULg

in Foundation: The Review of Science Fiction (1994)

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See detailMechanical Flow Obstruction after Heart Transplantation Diagnosed by Tee
CANIVET, Jean-Luc ULg; DEFRAIGNE, Jean ULg; Demoulin, Jean-Claude et al

in Annals of Thoracic Surgery (1994), 58(3), 890-1

We report a case of mechanical flow obstruction after heart transplantation caused by a prominent left atrium suture with a "pursestring" effect. The diagnosis was achieved by transesophageal ... [more ▼]

We report a case of mechanical flow obstruction after heart transplantation caused by a prominent left atrium suture with a "pursestring" effect. The diagnosis was achieved by transesophageal echocardiography. The mean transstenotic gradient was measured at 13 mm Hg. Because of the profound hemodynamic and multisystemic failure, no surgical correction was attempted. The postmortem examination confirmed the stenosis at the level of the left atrium. [less ▲]

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See detailAsthme et bêta2-agonistes de longue durée d'action
Bury, Thierry ULg; Kayambe, JM; Radermecker, Maurice ULg

in Médecine et Hygiène (1994), 52

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See detailFluid transfer in anorthosites and related rocks from Rogaland (Southwest Norway): Evidence from stable isotopes
Wilmart, Edith; Pineau, Françoise; Réjou-Michel, A. et al

in Earth & Planetary Science Letters (1994), 125

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See detailRecherches paléolithiques et mésolithiques en Belgique, 1993: le Trou Magrite, Huccorgne et l'Abri du Pape
Noiret, Pierre ULg; Otte, Marcel ULg; Straus, Lawrence et al

in Notae Praehistoricae (1994), 13

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See detailAnalysis of the penA gene of Pseudomonas cepacia 249.
Joris, Bernard ULg; Galleni, Moreno ULg; Frère, Jean-Marie ULg et al

in Antimicrobial Agents and Chemotherapy (1994), 38(2), 407-8

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See detailLa prothèse pénienne dans le traitement de l'impuissance: La décision du patient
Kempeneers, Philippe ULg; Andrianne, R.; Mormont, Christian ULg

in Cahiers de Sexologie Clinique (1994), 20(124), 31-36

In the population who look advice from our interdisciplinary team, penile prosthesis is estimated been indicated in about 13% of the cases. Among these 13% of patients to whom a penile implant was ... [more ▼]

In the population who look advice from our interdisciplinary team, penile prosthesis is estimated been indicated in about 13% of the cases. Among these 13% of patients to whom a penile implant was proposed, only 32% agreed to undergo the operation. From this statement, we wondered why some men require penile implantation and other ones resign. A follow-up survey allowed to compare the experience of 19 implants recipients to the experience of 17 patients who have refused this solution. The cost of the device appears being a very determinant argument in the decision to reject penile implantation. Our study fails to distinguls clearly the two groups of subjects on the basis of another motivation criterion. [less ▲]

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See detailUn formalisme unique peut-il décrire les phénomènes acoustiques et lumineux ?
Embrechts, Jean-Jacques ULg

in Bulletin d'Acoustique (1994), 16

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See detailCharacterization of an up-stream promoter directing extrapituitary expression of the human prolactin gene
Berwaer, M.; Martial, Joseph ULg; Davis, J. R.

in Molecular Endocrinology (1994), 8(5), 635-42

The human PRL gene is expressed outside pituitary lactotrophs in decidualized endometrium and lymphoid cells, but here the mRNA contains a 5'-untranslated region from an additional noncoding exon 1a. We ... [more ▼]

The human PRL gene is expressed outside pituitary lactotrophs in decidualized endometrium and lymphoid cells, but here the mRNA contains a 5'-untranslated region from an additional noncoding exon 1a. We have isolated a genomic DNA clone containing human PRL exon 1a with 2800 basepairs (bp) of 5'-flanking sequences. Sequencing locates exon 1a -5840 bp up-stream of the pituitary start site. To study its suspected regulatory function, various lengths of the 5'-flanking region were linked to the luciferase (Luc) reporter gene. Their ability to direct gene expression has been analyzed in transfection studies. The proximal 1620 bp of promoter sequence directed Luc expression in the T-lymphoid Jurkat cell line, and this was unaffected by 5'-deletion to the proximal 453 bp. However, further 5'-deletion to the most proximal 67 bp drastically reduced this activity by 90%. The exon 1a promoter was inactive in pituitary GH3 cells and HeLa cells; in contrast, the exon 1b pituitary promoter, active in GH3 cells, was inactive in Jurkat cells. DNase-I footprinting studies and further 5'- and 3'-deletion analysis identified factor-binding sites within an enhancer element located at -375/-212 bp, which contributed approximately 50% of the promoter activity. [less ▲]

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See detailBiostatistical studies of Western European allogamous populations of the Epipactis helleborine (L.) Crantz species group (Orchidaceae)
Tyteca, D.; Dufrêne, Marc ULg

in Systematic Botany (1994), 19(3), 424-442

[No abstract available]

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See detailFIL2, an extracellular Leucine-Rich Repeat protein, is specifically expressed in Antirrhinum flowers.
Steinmayr, M.; Motte, Patrick ULg; Sommer, H. et al

in Plant Journal (The) (1994), 5(4), 459-67

The expression of the Antirrhinum gene FIL2 is affected in mutants of the homeotic transcription factor DEFICIENS. Northern and Western blot analyses showed that FIL2 in wild-type Antirrhinum flowers is ... [more ▼]

The expression of the Antirrhinum gene FIL2 is affected in mutants of the homeotic transcription factor DEFICIENS. Northern and Western blot analyses showed that FIL2 in wild-type Antirrhinum flowers is expressed weakly in the petals and more abundantly in the reproductive organs; the gene is active in the filaments and anthers of stamens, and in the stigma and transmitting tissue of the carpels. The FIL2 protein is glycosylated with high mannose type glycan chains and is located in the middle lamella of the extracellular matrix. The amino acid sequence contains 10 tandem repeats, the composition of which is similar to the Leucine-Rich Repeat (LRR) motif found in mammals, Drosophila and yeast. The possibility that FIL2 might be a component of a cellular signalling mechanism, involving LRR-mediated protein-protein interactions is discussed. [less ▲]

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See detailRobotique pédagogique, d'un colloque à l'autre : vers l'émergence d'une communauté scientifique ?
Denis, Brigitte ULg; Baron, G. L.

in Sciences et Techniques Educatives [= STE] (1994), 1

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See detailExpected returns and volatility in european stock markets
Corhay, Albert ULg; Tourani-Rad, Alireza

in International Review of Economics and Finance (1994), 3(1), 45-56

The type of return generating process we test here on three European markets are GARCH and AR-GARCH in mean models with innovations that have either normal or student-t densities with time dependant ... [more ▼]

The type of return generating process we test here on three European markets are GARCH and AR-GARCH in mean models with innovations that have either normal or student-t densities with time dependant variances. These models are appealing in that they estimate time varying volatility in disturbances of stock returns series and ex-ante relationship between stock returns and volatility. Our results indicate that there is no statistically significant coefficient estimates for the volatility in the mean equation and that variance might not be appropriate as a measure of risk. Other proxies for risk should then be searched for. [less ▲]

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See detailReasoning about Infinite Computations
Vardi, Moshe Y.; Wolper, Pierre ULg

in Information & Computation (1994), 115(1), 1-37

We investigate extensions of temporal logic by connectives defined by finite automata on infinite words. We consider three different logics, corresponding to three different types of acceptance conditions ... [more ▼]

We investigate extensions of temporal logic by connectives defined by finite automata on infinite words. We consider three different logics, corresponding to three different types of acceptance conditions (finite, looping, and repeating) for the automata. It turns out, however that these logics all have the same expressive power and that their decision problems are all PSPACE-complete. We also investigate connectives defined by alternating automata and show that they do not increase the expressive power of the logic or the complexity of the decision problem. (C) 1994 Academic Press, Inc. [less ▲]

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See detailMonofrequency Forced Oscillation Technique for the Investigation of Pulmonary Function in Calves: In Vitro and in Vivo Studies
Close, Roland; Reinhold, Petra; Lekeux, Pierre ULg

in Research in Veterinary Science (1994), 56(3), 363-372

Parameters derived from the non-invasive and simple monofrequency forced oscillation technique were compared with classical parameters of ventilatory mechanics in order to assess its usefulness for the ... [more ▼]

Parameters derived from the non-invasive and simple monofrequency forced oscillation technique were compared with classical parameters of ventilatory mechanics in order to assess its usefulness for the investigation of pulmonary function in calves. To facilitate this comparison, theoretical derivations were coupled with in vitro measurements, using an artificial lung model, and with in vivo studies. These studies compared the oscillatory resistance parameters (Ros and Re) and the respiratory system compliance (Crs) against the classical pulmonary resistance (RL) and the dynamic compliance (Cdyn), respectively. Ros and Re were highly correlated (r > or = 0.87) with RL and the comparison between Crs and Cdyn gave a similarly high correlation (r > or = 0.88). Given its simplicity, its correspondence with classical parameters and its rapidity and reproducibility, monofrequency forced oscillation technique seems well suited for the investigation of pulmonary function under field conditions. [less ▲]

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See detailL'hémorragie pulmonaire induite par l'exercise chez le cheval: une énigme de la médecine équine ?
Art, Tatiana ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1994), 138

This review analyses the epidemiology, etiology, anatomo- and physiopathology, diagnose and prevention of the syndrome of exercise pulmonary hemorrhage in horses

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See detailEtude multicentrique du dosage de la transferrine déficiente en acide sialique par deux techniques chromatographiques
Vernet, M.; Renversez, J. C.; Revenant, M. C. et al

in Annales de Biologie Clinique (1994), 52

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See detailMuscle Fibre Type and Size, and Muscle Capillary Density in Young Double-Muscled Blue Belgian Cattle
Stavaux, D.; Art, Tatiana ULg; Mc Entee, Kathleen ULg et al

in Zentralblatt für Veterinarmedizin. Reihe A (1994), 41(3), 229-236

Bovine muscle biopsies were analysed for fiber type and capillary density by the acid ATP-ase and amylase-PAS methods respectively. Samples obtained from Belgian blue double muscled (DM) calves were ... [more ▼]

Bovine muscle biopsies were analysed for fiber type and capillary density by the acid ATP-ase and amylase-PAS methods respectively. Samples obtained from Belgian blue double muscled (DM) calves were compared for their fibre type, size and vascularization with samples from Friesian (F) calves. The animals were sampled both at 2 and 7 months of age. Changes in histochemical composition occurring with ageing, independently of the breed, and differences related to the muscle sampled by comparing biopsies obtained from the longissimus dorsi (LD) and gluteobiceps (GB) muscles in animals of both breed were also investigated. Independently of age and muscle, fibre type I percentage and area were significantly higher in F than in DM muscles. Type IIa area was significantly larger in F than in DM, while fibre type IIb percentage and area were higher in DM. The number of capillaries/mm2 was significantly higher in F than in DM. Fibre type IIa and IIb percentage as well as the diameter of the three fibre types was significantly higher in the oldest animals. Finally, independently of age and breed, fibre type I and IIb percentages were significantly higher in LD but lower in GB. The results mainly demonstrated that Belgian blue DM muscles present a higher proportion of IIb fibres and a lower capillary supply than F muscles. [less ▲]

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See detailChemically selected subclones of the CEM cell line demonstrate resistance to HIV-1 infection resulting from a selective loss of NF-kappa B DNA binding proteins.
Qian, J.; Bours, Vincent ULg; Manischewitz, J. et al

in Journal of Immunology (1994), 152(8), 4183-91

To delineate cellular genes that are required for optimal HIV-1 infection, CEM cells were subjected to treatment with the chemical mutagen ethylmethanesulfonate (EMS) and subclones were selected based on ... [more ▼]

To delineate cellular genes that are required for optimal HIV-1 infection, CEM cells were subjected to treatment with the chemical mutagen ethylmethanesulfonate (EMS) and subclones were selected based on their increased resistance to HIV-1 infection and reduced syncytium formation, despite relatively normal CD4 expression (20,000 to 25,000 receptors/cell). Two subclones with this phenotype demonstrated a diminished capacity of HIV-1 long terminal repeat-chloramphenicol acetyl transferase expression either after treatment with the protein kinase C activator PMA, or through Tat-mediated transactivation. In this study, we show that the cellular levels of the NF-kappa B DNA binding proteins (but not AP1 or SP1) are markedly reduced in these cell mutants both at the mRNA and protein levels, resulting in reduced nuclear localization of p50/p65 after PMA induction or treatment with the lymphokine TNF-alpha. Transient reconstitution with a plasmid expressing p50 resulted in partial recovery of PMA-inducible LTR-chloramphenicol acetyl transferase expression. These data suggest that, at least in the CEM T cell line, a selective reduction in the NF-kappa B DNA binding proteins is sufficient to curtail HIV-1 infection. [less ▲]

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See detailTHE BLOOD PROTEINS OF THE ANTARCTIC ICEFISH CHANNICHTHYS-RHINOCERATUS - BIOLOGICAL SIGNIFICANCE AND PURIFICATION OF THE 2 MAIN COMPONENTS
Feller, Georges ULg; Poncin, A.; Aittaleb, M. et al

in Comparative Biochemistry and Physiology. B : Comparative Biochemistry (1994), 109(1), 89-97

The lack of hemoglobin and of carbonic anhydrase in the blood of icefish suggest that substantial adaptations of the acid-base balance should occur in order to ensure blood pH homeostasis. The level of ... [more ▼]

The lack of hemoglobin and of carbonic anhydrase in the blood of icefish suggest that substantial adaptations of the acid-base balance should occur in order to ensure blood pH homeostasis. The level of peptidic histidyl and of reactive -SH groups per unit of body mass in icefish plasma are 12-13 times higher that those of Notothenia rossii, a common red-blooded Antarctic species. It is proposed that the high level of imidazole ring in icefish plasma improves the non-bicarbonate buffering capacity and that the reactive sulfhydryls are involved om a redox buffer as in some other hypoxia tolerant species. After plasma fractionation on Ultrogel AcA 34, the two main icefish serum proteins have been purified by DEAE cellulose chromatography (IFI) and by HPLC on anion exchange column (IF2). IFI has been identified as a cysteine-rich para-albumin and IF2 as an histidine-rich immunoglobulin-like protein. [less ▲]

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See detailSWIMMING PUPPY SYNDROME IN A LITTER OF BOUVIER-DES-FLANDRES
Poncelet, Luc; Gilbert, S.; Jauniaux, Thierry ULg et al

in Annales de Médecine Vétérinaire (1994), 138(2), 121-123

This paper describes the clinical, serologic, electrophysiologic and pathologic findings in three Bouvier des Flandres puppies exhibiting the swiming puppy syndrome. The puppies had no antibodies against ... [more ▼]

This paper describes the clinical, serologic, electrophysiologic and pathologic findings in three Bouvier des Flandres puppies exhibiting the swiming puppy syndrome. The puppies had no antibodies against distemper virus, T. gondii and N. caninum. A myopathy was suspected because spontaneous activities were disclosed in all muscle groups and muscles enzymes were elevated. However the pathologic findings were unable to confirm this hypothesis. [less ▲]

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See detailcerebral blood flow velocities measurements on anterior cerebral artery during general anesthesia and minor surgery
Battisti, Oreste ULg

in Circulation et Métabolisme du Cerveau (1994), 11

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See detailImmunological detection of beta-galactosidase-expressing cells by flow cytometry
Vanderplasschen, Alain ULg; Goltz, M.; Hanon, E.

in Biochemica (1994), 3

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See detailLa crise suicidaire de l'adolescent, un appel à la vie
Malchair, Alain ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1994), 2

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See detailFunctional effects of a muscarinic receptor blockade during acute respiratory distress syndrome in double-muscled calves
Genicot, Bruno; Mouligneau, Frédéric; Close, Roland et al

in Veterinary Record : Journal of the British Veterinary Association (1994), 134(5), 110-113

Eighteen Belgian white and blue double-muscled calves suffering from the acute respiratory distress syndrome were studied. Fifteen of the calves inhaled ipratropium bromide (0.6 mg) four times a day for ... [more ▼]

Eighteen Belgian white and blue double-muscled calves suffering from the acute respiratory distress syndrome were studied. Fifteen of the calves inhaled ipratropium bromide (0.6 mg) four times a day for three to four days whereas the other three control calves inhaled sterile 0.9 per cent saline. All the animals were injected with ceftiofur sodium (1 mg/kg/day) for five days, the first injection being given one hour after the first inhalation of ipratropium bromide or saline. Arterial oxygen tension, alveolar arterial oxygen difference, carbon dioxide tension and arterial pH, respiratory and heart rates, oscillatory resistance and phase angle, measured by the mono-frequency forced oscillation technique, were recorded both before and one hour and 168 hours after the first inhalation. The measurement of oscillatory resistance and phase angle made it possible to resolve the impedance of the respiratory system into its real and imaginary components. The oscillatory compliance (Cosc) was determined from the imaginary component (Im). By one hour after the first inhalation of ipratropium bromide the oscillatory resistance was already significantly reduced and Im and Cosc had significantly increased, but the other parameters showed no significant improvement. However, between one hour and 168 hours after the first inhalation all the parameters reached physiological values. The control calves did not show any change. It was concluded that the pulmonary dysfunction associated with the acute respiratory distress syndrome in these calves was at least partly due to a severe bronchoconstriction. [less ▲]

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See detailEvolutionary affiliation of the marine nitrogen-fixing cyanobacterium Trichodesmium sp. strain NlBB 1067, derived by 16s ribosomal RNA sequence analysis
Wilmotte, Annick ULg; Neefs, Jean-Marc; De Wachter, Rupert

in Microbiology (1994), 140

The 165 rRNA sequence of Trichodesmium sp. strain NlBB 1067 was determined and used for the construction of a distance tree and bootstrap analysis. The tree shows that, among the available cyanobacterial ... [more ▼]

The 165 rRNA sequence of Trichodesmium sp. strain NlBB 1067 was determined and used for the construction of a distance tree and bootstrap analysis. The tree shows that, among the available cyanobacterial 165 rRNA sequences, Trichodesmium NlBB 1067 has Oscillatoria PCC 7515 as its closest relative, presenting 94.9% of sequence similarity with the latter strain. This is in contrast to a difference of 9 mol O/O G + C in mean genomic DNA base composition between the two organisms. Nevertheless, the genotypic heterogeneity presented by a number of strains assigned to the genus Oscillatoria hinders a taxonomic decision on the separate existence of the genera Trichodesmium and Oscillatoria. The sequence of the internal transcribed spacer (ITS) between the 165 and 23s rRNA genes was also determined, as a possible marker to study inter- and intraspecif ic variability. The ITS contains the genes coding for tRNA1Ie and tRNAAia and its total length is 547 nucleotides. In six out of eight sequenced clones, there is a duplication of 29 nucleotides, surrounding the 5' end of the tRNA1Ie. [less ▲]

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See detailFear reactions of ewes to photographic images
Vandenheede, Marc ULg; Bouissou, Marie-France

in Behavioural Processes (1994), 32

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See detailPlace of MALT in the immune defence system.
Heinen, Ernst ULg

in Advances in Experimental Medicine and Biology (1994), 355

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See detailCytochemical and immunocytochemical study of coiled bodies in different cultured cell lines.
Thiry, Marc ULg

in Chromosoma (1994), 103(4), 268-76

We analyzed by different cytochemical and immunocytochemical approaches the biochemical compositon of coiled bodies in three different cultured cell lines. Coiled bodies are stained by the AgNOR staining ... [more ▼]

We analyzed by different cytochemical and immunocytochemical approaches the biochemical compositon of coiled bodies in three different cultured cell lines. Coiled bodies are stained by the AgNOR staining method and by the EDTA regressive staining method preferential for ribonucleoprotein (RNP). Using the in situ polyadenylate nucleotidyl transferase-immunogold technique or anti-RNA antibodies, we decisively demonstrated the presence of appreciable amounts of RNA in coiled bodies. Neither the in situ terminal deoxynucleotidyl transferase-immunogold technique nor anti-DNA antibodies revealed any DNA in coiled bodies. Coiled bodies thus appear as distinct regions of cell nuclei involved in some steps of RNA metabolism but not directly in RNA synthesis. Their relationships with the dense fibrillar component of the nucleolus and with interchromatin granule clusters are discussed. [less ▲]

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See detailDe réels progrès ont-ils été faits dans le traitement de l'ostéoporose ?
Reginster, Jean-Yves ULg; DEROISY, Rita ULg; Franchimont, P

in Les Nouvelles de Rhumatologie (1994), 4

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See detailSECULAR EVOLUTION OF THE VERTICAL COLUMN ABUNDANCES OF CHCLF2 (HCFC-22) IN THE EARTH'S ATMOSPHERE INFERRED FROM GROUND-BASED IR SOLAR OBSERVATIONS AT THE JUNGFRAUJOCH AND AT KITT-PEAK, AND COMPARISON WITH MODEL-CALCULATIONS
Zander, Rodolphe ULg; Mahieu, Emmanuel ULg; Demoulin, Philippe ULg et al

in Journal of Atmospheric Chemistry (1994), 18(2), 129-148

Series of high-resolution infrared solar spectra recorded at the International Scientific Station of the Jungfraujoch, Switzerland, between 06/1986 and 11/1992, and at Kitt Peak National Observatory ... [more ▼]

Series of high-resolution infrared solar spectra recorded at the International Scientific Station of the Jungfraujoch, Switzerland, between 06/1986 and 11/1992, and at Kitt Peak National Observatory, Tucson, Arizona (U.S.A.), from 12/1980 to 04/1992, have been analyzed to provide a comprehensive ensemble of vertical column abundances of CHClF2 (HCFC-22; Freon-22) above the European and the North American continents. The columns were derived from nonlinear least-squares curve fittings between synthetic spectra and the observations containing the unresolved 2nu6 Q-branch absorption of CHClF2 at 829.05 cm-1. The changes versus time observed in these columns were modeled assuming both an exponential and a linear increase with time. The exponential rates of increase at one-sigma uncertainties were found equal to (7.0 +/- 0.35)%/yr for the Junfraujoch data and (7.0 +/- 0.23)%/yr for the Kitt Peak data. The exponential trend of 7.0%/yr found at both stations widely separated in location can be considered as representative of the global increase of the CHClF2 burden in the Earth's atmosphere during the period 1980 to 1992. When assuming two realistic vertical volume mixing ratio profiles for CHClF2 in the troposphere, one quasi constant and the other decreasing by about 13% from the ground to the tropopause, the concentrations for mid-1990 were found to lie between 97 and 111 pptv (parts per trillion by volume) at the 3.58 km altitude of the Jungfraujoch and between .97 and 103 pptv at Kitt Peak, 2.09 km above sea level. Corresponding values derived from calculations using a high vertical resolution-2D model and recently compiled HCFC-22 releases to the atmosphere, were equal to 107 and 105 pptv, respectively, in excellent agreement with the measurements. The model calculated lifetime of CHClF2 was found equal to 15.6 years. The present results are compared critically with similar data found in the literature. On average, the concentrations found here are lower by 15-20% than those derived from in situ investigations; this difference cannot be explained by the absolute uncertainty of +/- 11% assigned presently to the infrared remote measurements. [less ▲]

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See detailAspergillose chez les oiseaux marins échoués sur la côte belge
Jauniaux, Thierry ULg; Coignoul, Freddy ULg

in Annales de Médecine Vétérinaire (1994), 138(4), 277-281

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species ... [more ▼]

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species. Debilitation and stress are favourable for the mycosis installation in captive wild birds (Zoo and rehabilitation centers). During 90-91 and 91-92 winters, 386 birds found dead at the belgian seashore were necropsied and 9 birds were carriers of specific lesions. Complementary investigations were undertaken. Most animals were oiled and had been kept for some time in rehabilitation centers. [less ▲]

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See detailCharacterization and Tumorigenicity of Spheroids Composed of Pigmented or Non Pigmented B16 Melanoma Cells
Coucke, P. H.; Gillet, Marie-Claire ULg; Bonjean, K. A. et al

in In Vivo (Athens, Greece) (1994), 8(3, May-Jun), 333-8

A parental line of mouse B16 melanoma cells (B16) and two derived cloned lines, either pigmented (B16P) or non pigmented (B16NP), were cultured in vitro as spheroids. After 48 hrs, the pigmented cells ... [more ▼]

A parental line of mouse B16 melanoma cells (B16) and two derived cloned lines, either pigmented (B16P) or non pigmented (B16NP), were cultured in vitro as spheroids. After 48 hrs, the pigmented cells (B16, B16P) formed smaller and looser aggregates, with higher rates of cell proliferation and lower amounts of extracellular matrix as compared to B16NP spheroids. The three lines were more tumorigenic when inoculated subcutaneously as spheroids than as isolated cells. Furthermore, B16P or B16 spheroids developed richly vascularized subcutaneous tumors and metastases more rapidly than B16NP aggregates. After intravenous injection of spheroids, the measurement with an image analyzer of the area of sections in lung colonies indicated that B16P colonies were larger and more numerous than those induced by B16NP cells. [less ▲]

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See detailNew Energy Levels in Ne II deduced from FTS spectra in the Infrared Region (1800-9000 cm-1)
Quinet, Pascal ULg; Palmeri, P.; Biémont, Emile ULg

in Physica Scripta (1994), 49

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See detailLa pompe musculo-veineuse de la personne âgée
Petermans, Jean ULg; Zicot, M.

in Journal des Maladies Vasculaires (1994), 19(2), 115-8

We study the musculo-venous pump in an elderly population, free of venous disease, by use of a digitized photoplethysmograph. We measure the venous refilling time (To) and the venous drainage (Vo) during ... [more ▼]

We study the musculo-venous pump in an elderly population, free of venous disease, by use of a digitized photoplethysmograph. We measure the venous refilling time (To) and the venous drainage (Vo) during active and passive movement. In the first part, we measure Vo and To during active and passive ankle flexions among 17 patients (34 limbs) aged 82.2 years. These variables are compared to the results of the same measurements obtained among 15 young adults aged 45.1 years (30 limbs). We find that To and Vo are significantly lower in the oldest population (To j 35.9 +/- 4.8 sec, To aged 16.1 +/- 5.2 sec, p < 0.001, Vo j 4.98 +/- 1.1%, Vo ag 2.97 +/- 1%, p < 0.001). In the second part of this work, a passive massage of the calf is substituted to the ankle flexions. This technique is applied to 19 elderly people aged 80.4 years (37 limbs) compared to 6 young adults aged 24 years (12 limbs). In these conditions the comparison is no more in favour of the younger group (To j 37 +/- 7.5 sec, To ag 30.6 +/- 4.1 sec, Vo j 4.03 +/- 1.5%, Vo ag 3.8 +/- 0.06%). The values measured in the elderly group are in the range of normal values. We conclude that senescence does not alter the venous system itself. The present work confirms the influence of extravascular factors as muscles, understanding and coordination of the motions, articular flexibility, on the performance of the musculo venous pomp. As far as possible, the muscular and articular activity has to be encouraged in elderly people in order to reduce the venous stasis. [less ▲]

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See detailL'enseignement du français instrumental à l'université: quelles possibilités?
Vanden Berghe, Kristine ULg; Sanctobin, Véronique; Slootmaekers, An et al

in Rencontres (1994), 5

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See detailThe functional proof of the diaphragm's specific type of motor innervation in Ongulae
Desmecht, Daniel ULg; Linden, Annick ULg; Leroy, Pascal ULg et al

in Pflügers Archiv : European Journal of Physiology (1994), 426

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See detailMalignant Hyperthermia and Severe Hypoglycemia after Reexposure to Halothane
Bichel, T.; Canivet, Jean-Luc ULg; Damas, Pierre ULg et al

in Acta Anaesthesiologica Belgica (1994), 45(1), 23-7

A four year child presented with an episode of malignant hyperthermia induced by reexposure to halothane. The episode was associated with early onset of a severe hypoglycemia and liver enzymatic ... [more ▼]

A four year child presented with an episode of malignant hyperthermia induced by reexposure to halothane. The episode was associated with early onset of a severe hypoglycemia and liver enzymatic perturbances. Etiology of these perturbances is hard to state precisely in this clinical context, but a hepatic toxicity of halothane and/or by dantrolene is considered. [less ▲]

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See detailSpectrum analysis of diaphragmatic global electromyograms in cattle, with special regard to appropriate strategy for detection of fatigue.
Desmecht, Daniel ULg; Linden, Annick ULg; Close, R. P. et al

in American Journal of Veterinary Research (1994), 55

Although the respiratory tract of healthy and diseased cattle has been intensively studied during the past few years, only a few attempts to detect dysfunctions of bovine inspiratory muscles have been ... [more ▼]

Although the respiratory tract of healthy and diseased cattle has been intensively studied during the past few years, only a few attempts to detect dysfunctions of bovine inspiratory muscles have been reported. Such technique would be useful in assessing the possibility of inspiratory muscle fatigue in the context of ventilatory failure. Fatigue in skeletal muscle is associated with characteristic changes in the electromyographic power spectrum. Power spectral analysis was therefore applied to cattle diaphragmatic electromyograms (EMGdi) to precisely determine the exact influence of motion and ECG artifacts, describe its basic frequency content, and extract a spectral index capable of providing an accurate warning of fatigue. The EMGdi was recorded via intramuscularly placed fishhook electrodes in 5 healthy young bulls during resting and stimulated respiration. The EMGdi and EGC signals were analyzed by use of power spectral density analysis after band-pass filtering (20 to 1,800 Hz). The EMGdi spectrum was concentrated in the band width 20 to 530 Hz. Electrode motion artifacts were absent, and it was always possible to find an electrode pair giving ECG-free EMGdi. Of the 12 power and frequency values used to quantitate the spectrum, the most stable was the centroid frequency. It was reproducible within and between calves and was only minimally altered by changing inspiratory load.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailA common system controls the induction of very different genes. The class-A beta-lactamase of Proteus vulgaris and the enterobacterial class-C beta-lactamase.
Datz, M; Joris, Bernard ULg; Azab, E A et al

in European Journal of Biochemistry (1994), 226(1), 149-57

Among the Enterobacteriaceae, Proteus vulgaris is exceptional in the inducible production of a 29-kDa beta-lactamase (cefuroximase) with an unusually high activity towards the beta-lactamase-stable ... [more ▼]

Among the Enterobacteriaceae, Proteus vulgaris is exceptional in the inducible production of a 29-kDa beta-lactamase (cefuroximase) with an unusually high activity towards the beta-lactamase-stable oximino-cephalosporins (e.g. cefuroxime and cefotaxime). Sequencing of the corresponding gene, cumA, showed that the derived CumA beta-lactamase belonged to the molecular class A. The structural gene was under the direct control of gene cumR, which was transcribed backwards and whose initiation codon was 165 bp away from that of the beta-lactamase gene. This resembled the arrangement of structural and regulator genes ampC and ampR of the 39-kDa molecular-class-C beta-lactamase AmpC present in many enterobacteria. Moreover, cloned genes ampD and ampG for negative modulation and signal transduction of AmpC beta-lactamase induction, respectively, were also able to restore constitutively CumA overproducing and non-inducible P. vulgaris mutants to the inducible, wild-type phenotype. The results indicate that controls of the induction phenomena are equivalent for the CumA and AmpC beta-lactamase. Very different structural genes can thus be under the control of identical systems. [less ▲]

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See detailOvarian endometrial cysts: the role of gonadotropin-releasing hormone agonist and/or drainage.
Donnez, Jacques; NISOLLE, Michelle ULg; Gillerot, Stéphane et al

in Fertility and Sterility (1994), 62(1), 63-6

Objective: To evaluate the role of GnRH agonist (GnRH-a) and/or drainage in the management of large endometriomas. DESIGN: This prospective clinical study was conducted in a parallel and randomized design ... [more ▼]

Objective: To evaluate the role of GnRH agonist (GnRH-a) and/or drainage in the management of large endometriomas. DESIGN: This prospective clinical study was conducted in a parallel and randomized design. SETTING: Department of Gynecology, Cliniques Universitaires St. Luc, Brussels, Belgium. PATIENTS: Eight infertile women with laparoscopically confirmed ovarian endometriotic cysts. After laparoscopic drainage of the ovarian cyst, patients were randomized. Patients in group I (n = 40) received no therapy. Patients in group II (n = 40) received GnRH-a therapy for 12 weeks. A second-look laparoscopy was performed after 12 weeks in each woman. RESULTS: After drainage, a quick recurrence of the endometrial cyst was observed in only group I. Indeed, the score and the cyst size were similar to the values observed before the first laparoscopy. In group II, a significant decrease in score and cyst diameter was observed. Ovarian biopsies revealed significant reduction in the stromal vascularization and a significant reduction in the mitotic activity in the group of women treated with GnRH-a. CONCLUSION: The quick recurrence of the ovarian cyst after drainage proved that drainage alone is ineffective. Drainage followed by GnRH-a was effective in the reduction of cyst size and the glandular mitotic activity. [less ▲]

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See detailDifferential Expression of the 67-Kd Laminin Receptor and 31-Kd Human Laminin-Binding Protein in Human Ovarian Carcinomas
van den Brule, F. A.; Berchuck, A.; Bast, R. C. et al

in European Journal of Cancer (1994), 30A(8), 1096-9

The expression of the 67-kD laminin receptor (67LR) and the 31-kD human laminin-binding protein (HLBP31), two proteins involved in cancer cell laminin interaction, was evaluated on 30 ovarian cancer ... [more ▼]

The expression of the 67-kD laminin receptor (67LR) and the 31-kD human laminin-binding protein (HLBP31), two proteins involved in cancer cell laminin interaction, was evaluated on 30 ovarian cancer specimens. Expression of the 67LR was increased (up to 2.5-fold, in 87% of the patients), while HLBP31 expression was downregulated in cancer cells compared with the normal tissue, as detected by northern blotting and immunohistochemistry. The immunohistochemical study demonstrated that the 67LR was significantly overexpressed (P < 0.05) in the group of patients whose cytoreductive surgery was suboptimal, and those with poor clinical outcome. No correlation was observed between HLBP31 expression and clinicopathological features. Increased expression of the 67LR appears to correlate with the invasive phenotype of ovarian cancer cells and suggests a role of the latter in ovarian cancer invasion. [less ▲]

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See detailAnti-LFA-1 (CD11a) monoclonal antibody interferes with the induction of neonatal tolerance to alloantigens
Schurmans, Stéphane ULg; Gonzalez, A.; Revilla, C. et al

in European Journal of Immunology (1994), 24

The injection of (C57BL/6 x BALB/c)F1 spleen cells into newborn BALB/c mice results in the induction of a specific cytotoxic T lymphocyte (CTL) tolerance to the alloantigens. On the contrary, alloreactive ... [more ▼]

The injection of (C57BL/6 x BALB/c)F1 spleen cells into newborn BALB/c mice results in the induction of a specific cytotoxic T lymphocyte (CTL) tolerance to the alloantigens. On the contrary, alloreactive CD4+ T cells persist in the host and are still able to activate autoreactive F1 B cells to produce autoantibodies. This state of "split tolerance" is closely associated with the development of a lupus-like autoimmune syndrome. The LFA-1 integrin plays a relevant role in homing, intercellular adhesion and tranduction of co-stimulatory signals in leukocytes. Because of the beneficial effects of anti-LFA-1 monoclonal antibodies (mAb) treatment in various models of organ transplantation and autoimmune disease, we have investigated if such a treatment could interfere with the induction of neonatal tolerance or the development of the autoimmune syndrome in F1 cell-injected newborn mice. For this purpose, BALB/c mice neonatally injected with F1 cells were treated from day 1 up to day 15 with a non-cytotoxic anti-LFA-1 (CD11a) mAb. Anti-LFA-1 mAb treatment interfered with the persistence of a stable chimerism and with the establishment of CTL tolerance, as shown by rejection of allogeneic skin grafts and F1 B cells, and by a normal in vitro CTL activity against the corresponding alloantigens. As a consequence, these mice did not develop the characteristic autoimmune features seen in close association with an effective induction of CTL tolerance to alloantigens. These results stress the importance of the interactions between LFA-1 and its ligands during the neonatal induction of tolerance to alloantigens [less ▲]

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See detailComparison of 125I and 3H testosterone radioimmunoassay methods in bovine serum
Miklos, M.; Renaville, Robert ULg; Tözser, J.

in Klin Kiserl Lab Med (1994), 22

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See detailTraitement de données par le logiciel Minitab
Claustriaux, Jean-Jacques ULg; Delvaux, A.

in Notes de Statistique et d'Informatique (1994), 1

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See detailRécidive post-opératoire de la maladie de Crohn après chirurgie curatrice
Belaiche, Jacques ULg; Louis, Edouard ULg

in Médecine et Hygiène (1994), 52

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See detailCONTINUOUS ENZYMATIC-SYNTHESIS OF 2'-DEOXYTHYMIDINE-5'(ALPHA-D-GLUCOPYRANOSYL)DIPHOSPHATE
Zervosen, Astrid ULg; ELLING, Lothar; KULA, Maria-Regina

in Angewandte Chemie (International ed. in English) (1994), 33(5), 571-572

The preparation of primary nucleotide sugars like dTDP-glucose with sucrose synthase, a glycosyl transferase in plants, provides an alternative in enzymatic synthesis to the use of highly specific ... [more ▼]

The preparation of primary nucleotide sugars like dTDP-glucose with sucrose synthase, a glycosyl transferase in plants, provides an alternative in enzymatic synthesis to the use of highly specific pyrophosphorylases. In an enzyme membrane reactor a continuous synthesis can be performed on preparative scale. [less ▲]

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See detailEvaluation de la fonction pulmonaire du cheval par la technique scintigraphique
Votion, Dominique ULg; Art, Tatiana ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1994), 138

Scintigraphy of the respiratory system, a technique used extensively in human medecine, provides a direct and non-invasive measure of both total and regional ventilation and perfusion of each lung. This ... [more ▼]

Scintigraphy of the respiratory system, a technique used extensively in human medecine, provides a direct and non-invasive measure of both total and regional ventilation and perfusion of each lung. This article remind you some nuclear notions and describes scintigraphical techniques for horses. The resuits of studies suggest that ventilation! perfusion scintigraphy provides valuable additionnai informations on regional lung function that are not obtainable from conventional investigations. The mucociliary clearance rates from the trachea can be determinated using scintigraphy and the differenttherapeutic drugs, which are claimed to increase mucokinesis, are successively presented. Methods of radiation protection in equine nuclear medecine are described [less ▲]

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See detailThe structures and catalytic mechanisms of active-site serine beta-lactamases.
Lamotte, Josette ULg; Knox, J.; Kelly, J. A. et al

in Biotechnology & Genetic Engineering Reviews (1994), 12

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See detailTnf-Alpha Is Involved in the Mechanism of Murine Thymic Lymphoma Prevention by Bone Marrow Grafting
Humblet, Chantal ULg; Deman, J.; Rongy, A. M. et al

in Advances in Experimental Medicine and Biology (1994), 355

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See detailLe rêve du neurobiologiste
Gauthier, Jean-Marie ULg

in Revue Belge de Psychanalyse (1994), 25

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See detailEffects of immunization against somatostatin on growth performances and growth hormone - insulin-like growth factor I and insulin plasma levels in young bulls.
Renaville, Robert ULg; Sneyers, M.; Massart, Serge et al

in Zootecnica e Nutrizione Animale (1994), 20(4),

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See detailLocalisation scintigraphique de tumeurs neuroendocrines et de leurs métastases par un analogue de la somatostatine: [111In-DTPA-d-phe1] octreotide
Beckers, Albert ULg; Pham, V. T.; Abs, R. et al

in Médecine & Chirurgie Digestives (1994), 23(3), 145-150

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See detailHST-FOC observations of a remarkable UV auroral event on Jupiter
Gérard, Jean-Claude ULg; Grodent, Denis ULg; Prangé, R. et al

in NASA STI/Recon Technical Report N (1994), 95

Two sets of UV (ultraviolet) images of the Jovian north aurora were obtained with the Faint Object Camera (FOC) on Hubble. The first series shows a very intense discrete arc in corotation with the planet ... [more ▼]

Two sets of UV (ultraviolet) images of the Jovian north aurora were obtained with the Faint Object Camera (FOC) on Hubble. The first series shows a very intense discrete arc in corotation with the planet. The maximum apparent H2 emission rate corresponds to an electron precipitation of approximately 1/sq Wm, a very large flux in comparison with the solar EUV (extreme ultraviolet) heating. The hugh particle heating rate of the auroral upper atmosphere of Jupiter is expected to cause a large transient temperature increase and generate strong thermospheric winds. Twenty hours later, the discrete arc had considerably decreased in brightness. The timescale and magnitude of the change in the UV aurora strongly suggests that the discrete Jovian auroral precipitation is related to large scale current system variations as are the Earth's discrete aurorae. [less ▲]

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See detailSuccessful removal of an intramedullary spinal paraganglioma from a dog
Poncelet, Luc; Snaps, Frédéric ULg; Jacobovitz, D. et al

in Journal of the American Animal Hospital Association (1994), 30(3), 213-216

An 11-year-old, mixed-breed dog suffering progressive asymmetric hind limb ataxia was diagnosed as having spinal cord compression at the L1 spinal level. An intramedullary, encapsulated tumor was ... [more ▼]

An 11-year-old, mixed-breed dog suffering progressive asymmetric hind limb ataxia was diagnosed as having spinal cord compression at the L1 spinal level. An intramedullary, encapsulated tumor was surgically removed. Tumor microscopic features, positive neuron-specific enolase (NSE) immunostaining, and Grimelius staining led to the diagnosis of paraganglioma. The dog was free from any neuroloaic signs 12 days after surgery. [less ▲]

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See detailLes disparités et les dynamiques territoriales. Introduction méthodologique
Merenne-Schoumaker, Bernadette ULg

in Bulletin de la Société Géographique de Liège (1994), (30), 5-14

This paper considers three kinds of methodological problems in the field of territorial dynamics and disparities. First of all, the definition of the concepts of disparity, dynamics and territory ... [more ▼]

This paper considers three kinds of methodological problems in the field of territorial dynamics and disparities. First of all, the definition of the concepts of disparity, dynamics and territory; secondly, the choice of spatial analysis levels, temporal limits and indicators and finally research into explanations. These are always very complicated and pratical despite the contribution of the major regional development theories and the new inquiries of regional science in the field of perceptions, networks and actors' roll. [less ▲]

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See detailA comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group.
Serruys, P. W.; de Jaegere, P.; Kiemeneij, F. et al

in The New England journal of medicine (1994), 331(8), 489-95

BACKGROUND: Balloon-expandable coronary-artery stents were developed to prevent coronary restenosis after coronary angioplasty. These devices hold coronary vessels open at sites that have been dilated ... [more ▼]

BACKGROUND: Balloon-expandable coronary-artery stents were developed to prevent coronary restenosis after coronary angioplasty. These devices hold coronary vessels open at sites that have been dilated. However, it is unknown whether stenting improves long-term angiographic and clinical outcomes as compared with standard balloon angioplasty. METHODS: A total of 520 patients with stable angina and a single coronary-artery lesion were randomly assigned to either stent implantation (262 patients) or standard balloon angioplasty (258 patients). The primary clinical end points were death, the occurrence of a cerebrovascular accident, myocardial infarction, the need for coronary-artery bypass surgery, or a second percutaneous intervention involving the previously treated lesion, either at the time of the initial procedure or during the subsequent seven months. The primary angiographic end point was the minimal luminal diameter at follow-up, as determined by quantitative coronary angiography. RESULTS: After exclusions, 52 patients in the stent group (20 percent) and 76 patients in the angioplasty group (30 percent) reached a primary clinical end point (relative risk, 0.68; 95 percent confidence interval, 0.50 to 0.92; P = 0.02). The difference in clinical-event rates was explained mainly by a reduced need for a second coronary angioplasty in the stent group (relative risk, 0.58; 95 percent confidence interval, 0.40 to 0.85; P = 0.005). The mean (+/- SD) minimal luminal diameters immediately after the procedure were 2.48 +/- 0.39 mm in the stent group and 2.05 +/- 0.33 mm in the angioplasty group; at follow-up, the diameters were 1.82 +/- 0.64 mm in the stent group and 1.73 +/- 0.55 mm in the angioplasty group (P = 0.09), which correspond to rates of restenosis (diameter of stenosis, > or = 50 percent) of 22 and 32 percent, respectively (P = 0.02). Peripheral vascular complications necessitating surgery, blood transfusion, or both were more frequent after stenting than after balloon angioplasty (13.5 vs. 3.1 percent, P < 0.001). The mean hospital stay was significantly longer in the stent group than in the angioplasty group (8.5 vs. 3.1 days, P < 0.001). CONCLUSIONS: Over seven months of follow-up, the clinical and angiographic outcomes were better in patients who received a stent than in those who received standard coronary angioplasty. However, this benefit was achieved at the cost of a significantly higher risk of vascular complications at the access site and a longer hospital stay. [less ▲]

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See detailVimentinoma, an Unusual Neoplasm of the Skin
Hermanns-Lê, Trinh ULg; Nikkels, Arjen ULg; Ammar et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (1994), 189(1), 84-86

We report an unusual benign neoplasm that developed in a child. Tumoral cells were filled with vimentin intermediate filaments. No other features of differentiation were found by immunohistochemistry and ... [more ▼]

We report an unusual benign neoplasm that developed in a child. Tumoral cells were filled with vimentin intermediate filaments. No other features of differentiation were found by immunohistochemistry and electron microscopy. 'Vimentinoma' appears to be the most appropriate name for this neoplasm. [less ▲]

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See detailEssai sur le rythme statuaire à la période protohistorique en Mésopotamie
Tunca, Önhan ULg

in Beiträge zur Altorientalischen Archäologie und Altertumskunde (1994)

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See detailBovine Leukemia Virus
Kettmann, Richard ULg; Burny, A.; Callebaut, I. et al

in The Retroviridae (1994)

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See detailModèles de cubage pour essences multi-tiges : application à des plantations d'acacia
Lejeune, Philippe ULg; Rondeux, Jacques ULg

in Cahiers Agricultures (1994), 3(3), 189-194

Tree-volume equations were devised to estimate the volume of wood (excluding bark) of Acacia auriculiformis A. Cunn ex Benth fuelwood plantations in Zaïre. The tables give the total volume of stems and ... [more ▼]

Tree-volume equations were devised to estimate the volume of wood (excluding bark) of Acacia auriculiformis A. Cunn ex Benth fuelwood plantations in Zaïre. The tables give the total volume of stems and branches to an upper girth limit of 9 cm, together with the volumes according to the following classes of girth : 9-14, 15-44 and over 45 cm. Because this species has a high proportion of multiple-stem trees (which begin forking below the breast-height level), girth at 1.30 m is a relatively meaningless concept. Taking the extent of this variable in tree volume estimation into account, various expressions of girth were investigated. Instead of considering each stem girth individually, a "standardised" girth at 1.30 m (from ground level) was adopted. For any given tree, this corresponds to the quadratic sum of all girths measured at 1,30 m. [less ▲]

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See detailHeterogeneous conversion of N2O5 to HNO3 in the post-Mount Pinatubo eruption stratosphere
Rinsland, Curtis P.; Gunson, Michaël R.; Abrams, M. C. et al

in Journal of Geophysical Research (1994), 99(D4), 8213-8219

Simultaneous stratospheric volume mixing ratio (VMR) profiles of dinitrogen pentoxide (N2O5) and nitric acid (HNO3) at sunrise between 25-degrees-N and 15-degrees-S latitude and profiles of HNO3 at sunset ... [more ▼]

Simultaneous stratospheric volume mixing ratio (VMR) profiles of dinitrogen pentoxide (N2O5) and nitric acid (HNO3) at sunrise between 25-degrees-N and 15-degrees-S latitude and profiles of HNO3 at sunset between 42-degrees-S and 53-degrees-S latitude have been derived from 0.01 cm-1 resolution infrared solar occultation spectra recorded 9 1/2 months after the massive eruption of the Mount Pinatubo volcano in the Philippine Islands. The measurements were obtained by the atmospheric trace molecule spectroscopy (ATMOS) Fourier transform spectrometer during the ATLAS 1 shuttle mission (March 24 to April 2, 1992). The measured HNO3 VMRs are higher at all altitudes and latitudes than corresponding values measured by the limb infrared monitor of the stratosphere (LIMS) instrument during the same season in 1979, when the aerosol loading was near background levels. The largest relative increase in the HNO3 VMR occurred near the equator at 30-km altitude, where the ATMOS/ATLAS 1 values are about a factor of 2 higher than the LIMS measurements. Two-dimensional model calculations show that the increase in HNO3 and the ATMOS/ATLAS 1 measurement of a steep decrease in the N2O5 VMR below 30 km can be explained by the enhanced conversion of N2O5 to HNO3 on the surfaces of the Mount Pinatubo sulfate aerosols. Our profile results demonstrate the global impact of the N2O5 + H2O --> 2HNO3 heterogeneous reaction in altering the partitioning of stratospheric odd nitrogen after a major volcanic eruption. [less ▲]

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See detailChloride Permeability of Rat Brain Membrane Vesicles Correlates with Thiamine Triphosphate Content
Bettendorff, Lucien ULg; Hennuy, Benoît ULg; De Clerck, Anne et al

in Brain Research (1994), 652(1), 157-160

Incubation of rat brain homogenates with thiamine or thiamine diphosphate (TDP) leads to a synthesis of thiamine triphosphate (TTP). In membrane vesicles subsequently prepared from the homogenates ... [more ▼]

Incubation of rat brain homogenates with thiamine or thiamine diphosphate (TDP) leads to a synthesis of thiamine triphosphate (TTP). In membrane vesicles subsequently prepared from the homogenates, increased TTP content correlates with increased 36Cl- uptake. A hyperbolic relationship was obtained with a K0.5 of 0.27 nmol TTP/mg protein. In crude mitochondrial fractions from the brains of animals previously treated with thiamine or sulbutiamine, a positive correlation between 36Cl- uptake and TTP content was found. These results, together with other results previously obtained with the patch-clamp technique, suggest that TTP is an activator of chloride channels having a large unit conductance. [less ▲]

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See detailExpression Of Interleukin-6 Receptors And Interleukin-6 Messenger-Rna By Bovine Leukemia Virus-Induced Tumor-Cells
Droogmans, L.; Cludts, I.; Cleuter, Y. et al

in Cytokine (1994), 6(6),

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See detailLa gynécologie dans les papyrus grecs de médecine
Marganne, Marie-Hélène ULg

in Acta Belgica Historiae Medicinae (1994), 7(4), 207-217

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See detailBovine Growth Hormone-Taqi Rflp And Quantitative Traits Breed Selected For Growth Performances And Meat Production
Sneyers, M.; Renaville, Robert ULg; Falaki, M. et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1994), 102(2),

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See detailCationic and secretory effects of BPDZ 44 and diazoxide in rat pancreatic islets
Antoine, M.-H.; Pirotte, Bernard ULg; Hermann, M. et al

in Experientia (1994), 50

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See detailAspects redistributifs de l'endettement public
Pestieau, Pierre ULg; Perelman, Sergio ULg

in La dette publique en Belgique (1994)

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See detailStatistical properties of daily returns : evidence from european stock markets
Corhay, Albert ULg; Tourani-Rad, Alireza

in Journal of Business Finance and Accounting (1994), 21(2), 271-282

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See detailComparaison de l'évolution de 2 litières biomaîtrisées à base de sciure ou de paille pour porcs à l'engraissement
Marlier, Didier ULg; Nicks, Baudouin ULg; Canart, Bernard et al

in Annales de Médecine Vétérinaire (1994), 138(1), 45-53

Two rooms of a pig house were used to study 2 deep litter systems where the animals were kept on a 50 cm thick layer of sawdust or of chopped straw (10 cm). Seven days before the arrival of the animals ... [more ▼]

Two rooms of a pig house were used to study 2 deep litter systems where the animals were kept on a 50 cm thick layer of sawdust or of chopped straw (10 cm). Seven days before the arrival of the animals, slurry and a microbial product used to stimulate the fermentation were added to the litters. Fifteen pigs on sawdust and seventien pigs on straw (floor spaces : 1.4 and 1.2 M2/pig) were fattened from 23.1 to 93.1 kg live weight. Excreta from pigs was dung into the bedding weekly and treated with the microbial product. This labour was considered as too hard in the straw room and was ended at day 105. No sawdust was added during the fattening period but straw was added 5 times to keep the pigs clean and to keep the temperature in the bedding higher than 30-degrees-C. The mean temperature in the sawdust bed was higher (38 +/- 5,4-degrees-C vs 35 +/- 6,7-degrees-C, p > 0,001) and more constant (mean daily variation 1,3 +/- 1,6 vs 2,2 +/- 2,4-degrees-C, p > 0,001) than the temperature recorded in the straw bed. The air temperature and the relative humidity were similar in the 2 rooms (21-degrees-C and 60 The concentrations of ammonia in the air were measured with Gastec tubes. The average ammonia concentrations recorded during the 7 days before the arrival of the animals (48 +/- 36 ppm vs 12 +/- 9,2 ppm) and those recorded after the eighth day (11 +/- 5,6 ppm vs 6,7 +/- 3,9 ppm) were significantly higher with the straw system compared with the sawdust system. The daily gains were not significantly different in the 2 rooms (552 g on average) and the food conversion ratios in the 2 rooms were 3,6 kg/kg (on sawdust) and 3,85 kg/kg (on straw). Carcasses were of equal quality. In conclusion, results were better with the sawdust bed than with the straw bed. The sawdust bed provided a higher temperature in the bedding and a lower ammonia concentration in the air. The routine weekly task of digging was easier in the sawdust bed and the bedding was used for a second batch. [less ▲]

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See detailHistorical seismicity of the lower Rhine and Meuse valleys from 600 to 1525 : a new critical review
Alexandre, Pierre ULg

in Netherlands Journal of Geosciences - Geologie en Mijnbouw (1994), 173

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See detailThe treatment of amiodarone-induced hyperthyroidism. Is there a place for surgery?
Meurisse, Michel ULg; Detroz, Bernard ULg; Messens, D. et al

in Acta Chirurgica Belgica (1994), 94(1), 36-41

In many instances amiodarone-induced hyperthyroidism has been reported as mild, thyroid functions returning to normal after discontinuation of the drug. Nevertheless, life-threatening amiodarone-induced ... [more ▼]

In many instances amiodarone-induced hyperthyroidism has been reported as mild, thyroid functions returning to normal after discontinuation of the drug. Nevertheless, life-threatening amiodarone-induced thyrotoxicosis has also been described. Conventional treatments such as with antithyroid drugs (Thionamide) and corticosteroids are essentially ineffective or fail to stop the dramatic course of the thyroid crisis. This limited efficacy of medical therapy, particularly in patients with previously--neglected or unknown--thyroid disease, prompted us to intervene surgically. We report a series of six patients who underwent total or nearly total thyroidectomy as first line therapy for four of them. Surgery resulted in rapid resolution of thyrotoxicosis with an uneventful postoperative course. This approach has the advantage of immediate and safe efficacy, low risk of relapse and finally, appears to be the only antithyroid treatment that permits continued therapy with amiodarone. [less ▲]

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See detailON THE FUNCTIONAL-CHARACTERIZATION OF THE ANALYTIC WAVE-FRONT SET OF AN HYPERFUNCTION
Bastin, Françoise ULg; LAUBIN, P.

in Mathematische Nachrichten (1994), 166

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See detailPsychophysiological correlates of suicidal behavior in depression. A preliminary study.
Hansenne, Michel ULg; Pitchot, William ULg; Gonzalez Moreno, A. et al

in Neuropsychobiology (1994), 30(1), 1-3

P300 and contingent negative variation (CNV) were recorded in depressive inpatients with and without history of suicide attempt. The results show a significant reduction of both P300 and CNV in patients ... [more ▼]

P300 and contingent negative variation (CNV) were recorded in depressive inpatients with and without history of suicide attempt. The results show a significant reduction of both P300 and CNV in patients who had attempted suicide as compared with patients who had not. Moreover, a significant correlation was found between the suicidal risk scale and CNV amplitude. Psychophysiological and biochemical implications are discussed. [less ▲]

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See detailShape processing and analysis using the calypter
Pirard, Eric ULg

in Journal of Microscopy (1994), 175(3), 214-221

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See detailNescio als 'Animal Metaphysicum'
Yans, Baudoin ULg

in Spiegel der Letteren (1994), (1), 45-62

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See detailEditorial comment intensive care
Lamy, Maurice ULg

in Current Opinion in Anaesthesiology (1994), 7

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See detailSynthesis, purification and kinetic properties of fluorescein-labelled penicillins
Lakaye, Bernard ULg; Damblon, Christian ULg; Jamin, Marc et al

in Biochemical Journal (1994), 300

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See detailLiège vue par une géographe
Merenne-Schoumaker, Bernadette ULg

in Cahiers de Clio (1994), (120), 5-16

Présentation générale de Liège

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See detailEvaluation d’une expérience de rénovation de l’enseignement fondamental: Méthodologie de recherche
Piéron, Maurice; Cloes, Marc ULg; Delfosse, Catherine et al

in Revue de l'Education Physique (1994), 34(2-3), 53-58

Les expériences pédagogiques de mise en œuvre de nouvelles méthodes ou structures de rénovation de l'enseignement sont particulièrement ardues à évaluer quant à leurs effets. Se déroulant en milieu ... [more ▼]

Les expériences pédagogiques de mise en œuvre de nouvelles méthodes ou structures de rénovation de l'enseignement sont particulièrement ardues à évaluer quant à leurs effets. Se déroulant en milieu naturel, elles subissent l'influence d'un grand nombre de variables qu'il est bien difficile voire impossible de contrôler et parfois simplement de prendre en compte. Les impondérables sont multiples. La voie la moins aléatoire consiste en une démarche multidimensionnelle qui analyse l'élève et l'enseignant, sous plusieurs points de vue, sans négliger des facteurs d'environnement socio-économiques qui peuvent également se révéler déterminants. ... [less ▲]

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See detailHow to improve the working conditions with an aerosol delivery equipment suitable for calves ?
Genicot, B.; Peckova, M.; Lamberty, S. et al

in American Journal of Respiratory & Critical Care Medicine (1994), 149

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See detailELEMENT DIFFUSION IN THE SOLAR INTERIOR
Thoul, Anne ULg; BAHCALL, J. N.; LOEB, A.

in Astrophysical Journal (1994), 421(2), 828-842

We study the diffusion of helium and other heavy elements in the solar interior by solving exactly the set of flow equations developed by Burgers for a multicomponent fluid, including the residual heat ... [more ▼]

We study the diffusion of helium and other heavy elements in the solar interior by solving exactly the set of flow equations developed by Burgers for a multicomponent fluid, including the residual heat-flow terms. No approximation is made concerning the relative concentrations, and no restriction is placed on the number of elements considered. We give improved diffusion velocities for hydrogen, helium, oxygen, and iron, in the analytic form derived previously by Bahcall & Loeb. These expressions for the diffusion velocities are simple to program in stellar evolution codes and are expected to be accurate to similar to 15%. We find that the inclusion of the residual heat flow terms leads to an increase in the hydrogen diffusion velocity. We compare our numerical results-with those obtained analytically by Bahcall & Loeb using a simplified treatment, as well as with those derived numerically by Michaud & Proffitt. We find that for conditions characteristic of the Sun, the results of Bahcall & Loeb for the hydrogen diffusion velocity are smaller than our more accurate numerical results by similar to 30%, except very near the center where the error becomes larger. The Michaud & Proffitt results differ from the numerical results derived here by less than or similar to 15%. Our complete treatment of element diffusion can be directly incorporated in a standard stellar evolution code by means of an exportable subroutine, but, for convenience, we also give simple analytical fits to our numerical results. [less ▲]

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See detailDistribution and Regulation of Estrogen-2-Hydroxylase in the Quail Brain
Balthazart, Jacques ULg; Stoop, R.; Foidart, Agnès ULg et al

in Brain Research Bulletin (1994), 35(4), 339-45

The anatomical distribution and endocrine regulation of the estrogen-2-hydroxylase activity were investigated in the brain of adult male and female Japanese quail. Significant levels of enzymatic activity ... [more ▼]

The anatomical distribution and endocrine regulation of the estrogen-2-hydroxylase activity were investigated in the brain of adult male and female Japanese quail. Significant levels of enzymatic activity were detected in all brain regions that were studied, but the highest levels were observed in preoptic and hypothalamic brain nuclei that are known to contain high levels of aromatase activity. These data are consistent with previous results suggesting that the placental aromatase is also responsible for the estrogen-2-hydroxylase activity. However, there is a marked sex difference and a control by T of aromatase activity in the quail brain, and no such difference in 2-hydroxylase activity could generally be detected except in the VMN. Further studies will be needed to know whether the previously published conclusions concerning the human placenta also apply to the brain. The present data are consistent with the idea that estrogens formed locally in the brain by testosterone aromatization could affect reproduction by interfering with the catecholaminergic transmission after being metabolized into catechol-estrogens. [less ▲]

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