References of "Article"
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See detailIn vitro culture of immature embryos of Phaseolus polyanthus Greenm. and Phaseolus vulgaris L.
Toussaint, André ULg; Clément, F.; Mergeai, Guy ULg et al

in Annual Report of the Bean Improvment Cooperative (2002), 45

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See detailVers un nouveau Droixhe
Frankignoulle, Pierre ULg; Stevens, Barbara

in Cahiers de l'Urbanisme (Les) (2002), 39

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See detailLe contrôle de la loyauté fiscale par la Cour des comptes et la Cour d’arbitrage : mission impossible ?
Rosoux, Géraldine ULg

in Administration Publique [=AP] : Revue du Droit Public et des Sciences Administratives (2002), 2-3-4

This article analyzes the concept of "tax loyalty" as a standard to be controlled by the Belgian constitutional Court and the Belgian Court of Audit.

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See detailLa reconnaissance et le financement de la laïcité organisée (I)
Sägesser, Caroline; Husson, Jean-François ULg

in Courrier Hebdomadaire du CRISP (2002), (1756), 3-43

This publication details the political process having led to the official recognition of the free thinkers organisations on a footing quite silmilar to religious denominations.

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See detailPrésentation. Du fantastique réel au réalisme magique
Denis, Benoît ULg

in Textyles : Revue des Lettres Belges de Langue Française (2002), (21), 7-9

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See detailLes conséquences des abus sexuels: le poids des préjugés ou "Il faut brûler Galilée"
Mormont, Christian ULg

in Forensic (2002), 10

Tous les mineurs exposés à des comportements sexuels inappropriés ne présentent pas des séquelles significatives à l'âge adulte. Le fait d'avoir vécu ces expériences sexuelles de façon négative ou de ... [more ▼]

Tous les mineurs exposés à des comportements sexuels inappropriés ne présentent pas des séquelles significatives à l'âge adulte. Le fait d'avoir vécu ces expériences sexuelles de façon négative ou de façon neutre ou positive semble avoir beaucoup d'importance et devrait être pris en compte dans les recherches [less ▲]

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See detailPregnancy and inflammatory bowel disease
Louis, Edouard ULg; Belaiche, Jacques ULg

in Acta Gastro-Enterologica Belgica (2002), 65(4, Oct-Dec), 230-232

Overall, around 25% of women with inflammatory bowel disease will conceive during their disease. Most of the women with inflammatory bowel disease will have a normal pregnancy and healthy children ... [more ▼]

Overall, around 25% of women with inflammatory bowel disease will conceive during their disease. Most of the women with inflammatory bowel disease will have a normal pregnancy and healthy children. However, specific problems may arise related to these pregnancies. This paper reviews what is known on fertility, risk of disease transmission, effect of the disease on the pregnancy and the reverse, delivery, medical follow up and treatment as well as breastfeeding in the setting of inflammatory bowel disease. [less ▲]

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See detailResults of a whole genome scan targeting QTL for growth and carcass traits in a Pietrain x Large White intercross
Nezer, C.; Moreau, L.; Wagenaar, D. et al

in Genetics, Selection, Evolution (2002), 34(3, May-Jun), 371-387

We herein report the results of a whole genome scan performed in a Pietrain x Large White intercross counting 525 offspring to map QTL influencing economically important growth and carcass traits. We ... [more ▼]

We herein report the results of a whole genome scan performed in a Pietrain x Large White intercross counting 525 offspring to map QTL influencing economically important growth and carcass traits. We report experiment-wide significant lod scores (> 4.6) for meatiness and fat deposition on chromosome SSC2, and for average daily gain and carcass length on chromosome SSC7. Additional suggestive lod scores (> 3.3) for fat deposition are reported on chromosomes SSC1, SSC7 and SSC13. A significant dominance deviation was found for the QTL on SSC1, while the hypothesis of an additive QTL could not be rejected for the QTL on SSC7 and SSC13. No evidence for imprinted QTL could be found for QTL other than the one previously reported on SSC2. [less ▲]

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See detailFédéralisme et extrême droite au Royaume-Uni
Jamin, Jérôme ULg

in Fédéralisme - Régionalisme (2002), 2

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See detailIncreased matrix metalloproteinase-3 serum levels in rheumatic diseases: relationship with synovitis and steroid treatment
Ribbens, Clio ULg; Martin y Porras, M.; Franchimont, N. et al

in Annals of the Rheumatic Diseases (2002), 61(2), 161-166

OBJECTIVE: To determine matrix metalloproteinase-3 (MMP-3) serum levels in patients with rheumatic diseases and to study the relation between MMP-3 and C reactive protein (CRP) levels. METHODS: MMP-3 ... [more ▼]

OBJECTIVE: To determine matrix metalloproteinase-3 (MMP-3) serum levels in patients with rheumatic diseases and to study the relation between MMP-3 and C reactive protein (CRP) levels. METHODS: MMP-3 serum levels were determined by enzyme linked immunosorbent assay (ELISA) in (a) patients with active inflammatory rheumatic diseases: rheumatoid arthritis (RA), psoriatic arthritis, polymyalgia rheumatica, acute crystal arthritis, and ankylosing spondylitis; (b) patients with active inflammatory systemic diseases: cutaneo-articular or renal systemic lupus erythematosus (SLE), systemic sclerosis, and vasculitides; (c) patients with non-inflammatory rheumatic diseases: osteoarthritis and fibromyalgia; (d) critically ill patients without rheumatic diseases, representing an acute inflammatory control group; (e) healthy controls. RESULTS: MMP-3 serum levels were significantly increased in patients with active RA, psoriatic arthritis, and polymyalgia rheumatica, whether treated or not by corticosteroids, and in female patients with acute crystal arthritis. MMP-3 serum levels were normal in steroid-free patients with active cutaneo-articular or renal SLE, systemic sclerosis, and vasculitides but were significantly increased in steroid treated patients. MMP-3 levels were normal in fibromyalgia, osteoarthritis, ankylosing spondylitis, and acute inflammatory controls. MMP-3 was significantly correlated with CRP in RA (r=0.5, p=0.0004) but not in any of the other disease groups. CONCLUSIONS: MMP-3 serum levels are increased in inflammatory rheumatic diseases characterised by joint synovitis, such as RA, polymyalgia rheumatica, psoriatic arthritis, and acute crystal arthritis-that is, whether the diseases are acute or chronic, erosive or not. They are normal in SLE, systemic sclerosis, and vasculitides as well as in non-rheumatic inflammatory controls, but are significantly increased by steroids. These data strongly suggest that serum MMP-3 reflects synovial inflammation. [less ▲]

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See detailIntravascular malignant lymphomatosis: report of 2 neurological cases
Vandenheede, Michel; Dioh, Alioune ULg; Maertens De Noordhout, Alain ULg et al

in Acta Neurologica Belgica (2002), 102(2), 76-81

We report two cases of intravascular malignant lymphomatosis (IML) with a clinical expression limited to the central nervous system. The first patient presented with signs of cerebral, cerebellar and ... [more ▼]

We report two cases of intravascular malignant lymphomatosis (IML) with a clinical expression limited to the central nervous system. The first patient presented with signs of cerebral, cerebellar and spinal cord involvement. The second had an isolated involvement of the spinal cord. In both cases the diagnosis was made at post-mortem examination; pre-mortem examination of biopsy tissue from peripheral nerve and muscle in the first case, spleen and liver in the second were unhelpful for the diagnosis of lymphoma. We review the published literature on IML, its ante-mortem diagnosis and treatment. [less ▲]

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See detailEtalonnage de la figure complexe de Rey sur une population d’enfants de six à douze ans
Garcet, Serge ULg; Deltour, Jean-Jacques; Remacle, Michel

in Revue Scientifique de l'AIGS (2002), 1

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See detailTNF-alpha protects human primary articular chondrocytes from nitric oxide-induced apoptosis via nuclear factor-kappaB
Relic, Biserka ULg; Bentires-Alj, Mohamed; Ribbens, Clio ULg et al

in Laboratory Investigation : Journal of Technical Methods & Pathology (2002), 82(12), 1661-1672

TNF-alpha plays a key role in rheumatoid arthritis, but its effect on chondrocyte survival is still conflicting. In the present study, we tested how TNF-alpha influences chondrocyte survival in response ... [more ▼]

TNF-alpha plays a key role in rheumatoid arthritis, but its effect on chondrocyte survival is still conflicting. In the present study, we tested how TNF-alpha influences chondrocyte survival in response to nitric oxide (NO)-related apoptotic signals, which are abundant during rheumatoid arthritis. Human primary articular chondrocytes or cartilage explants were pretreated with TNF-alpha for 24 hours and then treated with the proapoptotic NO donor sodium-nitro-prusside (SNP) for an additional 24 hours. TNF-alpha pretreatment markedly protected chondrocytes from SNP-induced cell death. Preincubation of chondrocytes with TNF-alpha inhibited both SNP-induced high-molecular weight DNA fragmentation and annexin V-FITC binding. Of interest, TNF-alpha induced persistent nuclear factor-kappaB (NF-kappaB)-DNA binding activity even in the presence of SNP, mirroring apoptosis protection effects. Both the TNF-alpha antiapoptotic effect and NF-kappaB-DNA binding activity were significantly inhibited by NF-kappaB inhibitors, Bay 11-7085, MG-132, and adenovirus-expressing mutated IkappaB-alpha. Phosphatidylinositol-3 kinase inhibitor LY 294002 also markedly inhibited the antiapoptotic effect of TNF-alpha. In primary chondrocytes, TNF-alpha induced expression of the antiapoptotic protein Cox-2, which persisted in the presence of SNP, and a specific Cox-2 inhibitor significantly blocked the TNF-alpha protective effect. We therefore conclude that TNF-alpha-mediated protection of chondrocytes from NO-induced apoptosis acts through NF-kappaB and requires Cox-2 activity. [less ▲]

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See detailSoil Seed Bank And Seed Dormancy In Wild Populations Of Lima Bean (Fabaceae): Considerations For In Situ And Ex Situ Conservation
Degreef, J.; Rocha, O.; Vanderborght, T. et al

in American Journal of Botany (2002), 89(10), 1644-1650

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See detailEclatement des mobilités d'achats et recomposition des territoires : le cas de l'Ardenne du Nord-Est.
Schmitz, Serge ULg; Halleux, Jean-Marie ULg

in Mosella (2002), 26(3-4), 425-432

Lived world are structured by regular journeys. Many journeys are constrained, other, such as shopping mobilities, present a higher level of freedom. New mobilities and new commercial localisation ... [more ▼]

Lived world are structured by regular journeys. Many journeys are constrained, other, such as shopping mobilities, present a higher level of freedom. New mobilities and new commercial localisation strategies lead to new travels network. The aim of the paper is to study shopping behaviours in North-Eastern Ardennes in order to underline the increasing disparities between shopping mobilities, lived world, homeland and institutional territories. When space behaviours make and remake territorial frames. [less ▲]

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See detailUntersuchung von Spaltungs- und Koaleszenzvorgängen in einer Messzelle mit pulsierten Füllkörpern
Klinger, S; Henschke, M; Pfennig, Andreas ULg

in Chemie Ingenieur Technik (2002), 74(3), 256-261

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See detailSimultaneous mining of linkage and linkage disequilibrium to fine map quantitative trait loci in outbred half-sib pedigrees: Revisiting the location of a quantitative trait locus with major effect on milk production on bovine chromosome 14
Farnir, Frédéric ULg; Grisart, B.; Coppieters, Wouter ULg et al

in Genetics (2002), 161(1), 275-287

A maximum-likelihood QTL mapping method that simultaneously exploits linkage and linkage disequilibrium and that is applicable in outbred half-sib pedigrees is described. The method is applied to fine map ... [more ▼]

A maximum-likelihood QTL mapping method that simultaneously exploits linkage and linkage disequilibrium and that is applicable in outbred half-sib pedigrees is described. The method is applied to fine map a QTL with major effect on milk fat content in a 3-cM marker interval on proximal BTA14. This proximal location is confirmed by applying a haplotype-based association method referred to as recombinant ancestral haplotype analysis. The origin of the discrepancy between the QTL position derived in this work and that of a previous analysis is examined and shown to be due to the existence of distinct marker haplotypes associated with QTL alleles having large substitution effects. [less ▲]

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See detailQuelques résultats prometteurs pour une sylviculture de l'Aulne glutineux en Wallonie.
Claessens, Hugues ULg; Thibaut, A.; Rondeux, Jacques ULg

in Revue Forestière Française (2002), 54(3), 259-270

In Belgium, black alder is well known for its ecological functions, but is generally considered as a secondary species without any true economic value. The present study, based on data pertaining to 166 ... [more ▼]

In Belgium, black alder is well known for its ecological functions, but is generally considered as a secondary species without any true economic value. The present study, based on data pertaining to 166 plots, aims at evaluating the potential of black alder silviculture in the Walloon forest (Southern Belgium). We successively analysed dominant height growth, dominant girth growth and solid stem volume over time. It appears that by controlling competition within stands it should be possible to produce quality, 150-cm girth logs within 50 – 100 years, depending on the level of productivity. The German tables of Mitscherlich (in Schöber, 1975) seem to be most suitable for describing the growth parameters of the Belgian alder stands over time and black alder stand production can be estimated at 3 to 9 m3/ha/year according to site classes. We can conclude that black alder silviculture can be a viable economic activity. [less ▲]

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See detailDetermination of a coalescence parameter from batch-settling experiments
Henschke, M; Schlieper, L; Pfennig, Andreas ULg

in Chemical Engineering Journal (2002), 85((2-3)), 369-378

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See detailModélisation de l’impact de mollusques filtreurs sur le phytoplancton de la Moselle.
Descy, Jean-Pierre; Everbecq, Etienne ULg; Gosselain, Véronique ULg et al

in Tribune de l'Eau (La) (2002), 55-56(n° 619-620), 130-138

Le modèle POTAMON (Everbecq & al., 2001) a été utilisé pour simuler l'effet de mollusques bivalves (principalement Dreissena polymorpha) sur le phytoplancton et le zooplancton d'une rivière de plaine, la ... [more ▼]

Le modèle POTAMON (Everbecq & al., 2001) a été utilisé pour simuler l'effet de mollusques bivalves (principalement Dreissena polymorpha) sur le phytoplancton et le zooplancton d'une rivière de plaine, la Moselle. Les simulations suggèrent un impact significatif des mollusques filtreurs sur le phytoplancton, en particulier en été. Les simulations ont également permis d'établir un bilan carbone de la rivière et d'expliquer les déficits en oxygène observés dans la Moselle. [less ▲]

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See detailL'entrée en vigueur du permis d'environnement et du permis unique
Pâques, Michel ULg

in Actualité législative en droit immobilier (2002)

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See detailRadiologic features poorly predict clinical outcomes in knee osteoarthritis.
Bruyère, Olivier ULg; Honore, Aline; Rovati, Lucio C et al

in Scandinavian Journal of Rheumatology (2002), 31(1), 13-6

OBJECTIVES: To assess the impact of radiographic severity and progression on pain and disability. METHODS: Measurements of mean joint space width (JSW), narrowest join space (NJS) point and assessment of ... [more ▼]

OBJECTIVES: To assess the impact of radiographic severity and progression on pain and disability. METHODS: Measurements of mean joint space width (JSW), narrowest join space (NJS) point and assessment of symptoms by the WOMAC questionnaire were performed at baseline and after three years in 212 subjects over 50 years with primary knee OA. RESULTS: At baseline, JSW and NJS were not significantly correlated with the scores recorded for the WOMAC global index or its pain, stiffness or function subscales. A statistically significant correlation was observed between the joint space narrowing over three years and the changes observed in the pain subscale of the WOMAC during the same period. The three-year changes in the global WOMAC index in patients within the lowest and the highest quartiles of mean joint space width at baseline showed, in both cases, a statistically (p<0.05) significant favorable difference between patients treated with glucosamine sulphate and those having received placebo. CONCLUSION: Radiographic and clinical progressions of the disease are significantly associated but the clinical relevance of the association is questionable. [less ▲]

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See detailPhytoremediation of polyaromatic hydrocarbons, anilines and phenols
Harvey, P. J.; Campanella, Bruno ULg; Castro, P. et al

in Environmental Science and Pollution Research (2002), 9

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See detailModellierung von Faserbett-Koaleszenzabscheidern
Speth, H; Pfennig, Andreas ULg; Chatterjee, M et al

in Chemie Ingenieur Technik (2002), 74(3), 266-270

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See detailBlanche-Neige était-elle transsexuelle ?
Michel, Aude; Mormont, Christian ULg

in Encéphale (L') (2002), 28(1), 59-64

The Rorschach Ink Blot test is considered to be an essential analytical instrument when studying the personalities of individuals presenting gender identity disorders, in particular, in the context of a ... [more ▼]

The Rorschach Ink Blot test is considered to be an essential analytical instrument when studying the personalities of individuals presenting gender identity disorders, in particular, in the context of a sex change request. Nevertheless, there exist less than 20 studies of transsexualism utilising the Rorschach since the creation of this diagnostic category in 1953. This research has mostly concerned itself with relations between psychopathology and transsexualism. Practically non-existent are studies investigating the psychological conditions that permit, shape or induce sex change requests in individuals. Transsexuals request the removal of their genitals through mutilation surgery, which can be seen as subjects literally crying out to be castrated. This request is all the more surprising given that castration, in psychoanalytic terms, is considered to be the most severe punishment that an individual (woman or man) can be threatened with. Therefore, we asked ourselves which psychic conditions could motivate such as request. Based on any earlier study where answers (some explicit, others symbolic) given by sex-change applicants tested on the Rorschach were analysed, results seemed to suggest a counter-phobic attitude underlying sex-reassignment requests (28). According to these hypotheses, the fear of castration (banal as such) can only be overcome through the active search for castration itself. In opting for castration, the transsexual puts an end to the states of anxious waiting that are dominated by feelings of the incertitude and unpredictability of an eventual castration. Once obtained, the threat it constituted disappears, and with it so does the fear. Thus, by taking this active and voluntary step, the subject is no longer exposed to an imminent danger in a passive manner. This in itself creates a great feeling of relief, if not of actual pleasure in the subject (28). In this article, we postulated in a purely speculative manner, the existence of one or several modalities in the transsexual dynamics. Nevertheless, one can ask oneself about the possibility of a request based on a desire rather than on a defense, or even on the existence of a defensive process diametrically opposed to the counter-phobic attitude and which, instead of actively provoking the dreaded reality, would privilege its avoidance and the search of passivity. This latter hypothesis has the advantage of being rather easy to explore with the Rorschach because, according to Exner, the predominance of passive compared to active human movement responses (which he terms the Snow White Syndrome) indicates the propensity to escape into passive fantasies and the tendency to avoid the initiative for behaviour or decision-making, if other people can do it in the subject's place (12). Our results largely confirmed the hypothesis of the existence of an opposite mechanism, as a third of subjects (n = 26) presented Snow White Syndrome. According to Exner, these transsexuals are typically characterized by hiding into a world of make believe, avoiding all responsibility, as well as any decision-making. This passivity in our Snow White Syndrome group was all the more remarkable in that, on the whole, it infiltrated into all the movement responses and seemed to define a rigid style of thinking and mental elaboration, in addition to a suggestive content of passivity. However, this condition cannot be associated with a general lack of dynamism or energy. In fact, the treatment of information, which provides data concerning the motivation to treat a stimulus field of the stimulus--whether this concerns the capture (L) of the stimulus or the elaboration (DQ+) of the response--displayed a sufficient amount of motivation. Furthermore, internal resources (EA) were considerable and were brought into play whenever it was necessary to adopt a behaviour or make a decision. Furthermore, based on these Rorschach findings, we note that in transsexuals with Snow White Syndrome, there is a stereotyped tendency to shy away from difficulties by seeking refuge in realistic representations (but that lack in variety), which could be materialized by actions, but where the initiative is delegated to others. These transsexuals appear to shy away from the difficulties of life by seeking refuge into a world of fantasy, which they fill with the representations borrowed from reality (rather than fantasy) and consequently that are liable to be transposed, if necessary, back into reality. Therefore, one can better understand why they shun away from the deceiving reality that their physical sex represents, into the satisfying dream where they possess the genitals of the opposite sex, that is, a perfectly real organ, no longer the result of the subject's fantasy world. [less ▲]

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See detailLa forêt et la protection du sol dans le cadre d'aménagement forestiers intégrés
Huart, O.; Adam, V.; Quevy, B. et al

in Fiche technique (2002), (14),

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See detailOxidative stress in equine medicine - Current knowledge
Kirschvink, Nathalie; Lekeux, Pierre ULg

in Pferdeheilkunde (2002), 18(6), 569-573

Oxidative stress has become of increasing interest in research and human medicine. Oxidants or reactive oxygen species are generated by metabolic reactions and play an important role for the immune ... [more ▼]

Oxidative stress has become of increasing interest in research and human medicine. Oxidants or reactive oxygen species are generated by metabolic reactions and play an important role for the immune defence and the "redox-regulation" of gene expression, In physiological conditions, different categories of antioxidants maintain the equilibrium between the pro-oxidant burden and the endogenous antioxidant defence. However, when an imbalance between oxidants and antioxidants in favour of oxidants occurs, oxidative stress might induce irreversible lesions that can be evidenced and characterised by oxidant markers. In equine medicine, it has been shown that oxidative stress is occurring in lower airway disease and equine motor neuron disease. Moreover, adopted antioxicants therapy appears to have a beneficial effect on the antioxidant-oxidant imbalance. Exercise-induced oxidative stress and its impact on animal welfare and performance are also under investigation in equine sports medicine, Oxidative stress has been demonstrated to cepend on exercise type, intensity and duration. It might be modulated by training and/or adopted antioxidant therapy, aiming to maintain the antioxidant-oxidant equilibrium and thereby to improve animal welfare. [less ▲]

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See detailAn efficient time discretization procedure for finite element-electronic circuit equation coupling
Dular, Patrick ULg; Kuo-Peng, P.

in Compel-the International Journal for Computation and Mathematics in Electrical and Electronic Engineering (2002), 21(2), 274-285

An efficient and robust time discretization procedure of theta type is proposed in the frame of the finite element-circuit equation coupling for electronic circuits with switches, i.e. the use of diodes ... [more ▼]

An efficient and robust time discretization procedure of theta type is proposed in the frame of the finite element-circuit equation coupling for electronic circuits with switches, i.e. the use of diodes, thyristors and transistors. This procedure enables the use of the Crank-Nicolson scheme whatever the circuit and its working conditions by eliminating the undesirable oscillations of the solution peculiar to this scheme. It is based on the accurate determination of the switching instants and on a local modification of the theta parameter. [less ▲]

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See detailMechanisms controlling the oxygen consumption in experimentally induced hypochloremic alkalosis in calves
Cambier, Carole ULg; Clerbaux, Thierry; Amory, Hélène ULg et al

in Veterinary Research (2002), 33

The study was carried out on healthy Friesian calves (n = 10) aged between 10 and 30 days. Hypochloremia and alkalosis were induced by intravenous administration of furosemide and isotonic sodium ... [more ▼]

The study was carried out on healthy Friesian calves (n = 10) aged between 10 and 30 days. Hypochloremia and alkalosis were induced by intravenous administration of furosemide and isotonic sodium bicarbonate. The venous and arterial blood samples were collected repeatedly. 2,3-diphosphoglycerate (2,3-DPG), hemoglobin and plasmatic chloride concentrations were determined. The red blood cell chloride concentration was also calculated. pH, PCO2 and PO2 were measured in arterial and mixed venous blood. The oxygen equilibrium curve (OEC) was measured in standard conditions. The correspondence of the OEC to the arterial and mixed venous compartments was calculated, taking blood temperature, pH and PCO2 values into account. The oxygen exchange fraction (OEF%), corresponding to the degree of blood desaturation between the arterial and mixed venous compartments and the amount of oxygen released at the tissue level by 100 mL of blood (OEF Vol%) were calculated from the arterial and mixed venous OEC, combined with PO2 and hemoglobin concentration. Oxygen delivery (DO2) was calculated using the arterial oxygen content, the cardiac output measured by thermodilution, and the body weight of the animal. The oxygen consumption (VO2) was derived from the cardiac output, OEF Vol% and body weight values. Despite the plasma hypochloremia, the erythrocyte chloride concentration was not influenced by furosemide and sodium bicarbonate infusion. Due to the alkalosis-induced increase in the 2,3-DPG, the standard OEC was shifted to the right, allowing oxygen to dissociate from hemoglobin more rapidly. These changes opposed the increased affinity of hemoglobin for oxygen induced by alkalosis. Moreover, respiratory acidosis, hemoconcentration, and the slight decrease in the partial oxygen pressure in mixed venous blood (Pvo(2)) tended to improve the OEF Vol% and maintain the oxygen consumption in a physiological range while the cardiac output, and the oxygen delivery were significantly decreased. It may be concluded that, despite reduced oxygen delivery, oxygen consumption is maintained during experimentally induced hypochloremic alkalosis in healthy 10-30 day old calves [less ▲]

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See detailThree-dimensional organization of active rRNA genes within the nucleolus.
Cheutin, Thierry; O'Donohue, Marie*-Francoise; Beorchia, Adrien et al

in Journal of Cell Science (2002), 115(Pt 16), 3297-307

In this work, we have localized transcribing rRNA genes at the ultrastructural level and described their three-dimensional organization within the nucleolus by electron tomography. Isolated nucleoli ... [more ▼]

In this work, we have localized transcribing rRNA genes at the ultrastructural level and described their three-dimensional organization within the nucleolus by electron tomography. Isolated nucleoli, which exhibit a reduced transcriptional rate, were used to determine the sites of initial BrUTP incorporation (i.e. rRNA synthesis by the transcriptional machinery). Using pulse-chase experiments with BrUTP and an elongation inhibitor, cordycepin, it was possible to precisely localize the initial sites of BrUTP incorporation. Our data show that BrUTP incorporation initially takes place in the fibrillar centers and that elongating rRNAs rapidly enter the surrounding dense fibrillar component. Furthermore, we investigated the spatial arrangement of RNA polymerase I molecules within the whole volume of the fibrillar centers. Electron tomography was performed on thick sections of cells that had been labeled with anti-RNA polymerase I antibodies prior to embedding. Detailed tomographic analyses revealed that RNA polymerase I molecules are mainly localized within discrete clusters. In each of them, RNA polymerase I molecules were grouped as several coils, 60 nm in diameter. Overall, these findings have allowed us to propose a model for the three-dimensional organization of transcribing rDNA genes within the nucleolus. [less ▲]

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See detailEffect of prenatal androgen receptor antagonist or aromatase inhibitor on the differentiation of neuronal Fos responses to estrous female pheromones in the rat accessory olfactory system
Dominguez, Emilio; Portillo, Wendy; Baum, Michael J et al

in Physiology & Behavior (2002), 75

Many socially relevant odors are detected in rodent species by the vomeronasal organ and subsequently processed by the accessory olfactory system (AOS). We previously found that gonadectomized male and ... [more ▼]

Many socially relevant odors are detected in rodent species by the vomeronasal organ and subsequently processed by the accessory olfactory system (AOS). We previously found that gonadectomized male and female rats treated in adulthood with testosterone propionate (TP) showed equivalent Fos responses in the AOS to odors derived from estrous females. Likewise, in contrast with numerous other mammalian species, gonadectomized female rats show surprisingly high levels of male-typical mounting behavior in response to adult TP. We tested the hypothesis that prenatal testosterone (T) exposure, acting via androgen receptors (ARs) or via estrogen receptors, masculinizes the AOS in rats of both sexes. Pregnant dams were treated with either the AR blocker, Flutamide, the aromatase inhibitor, 1,4,6-androstatriene-3,17-dione (ATD), or nothing (control) to assess the role of prenatal androgen and estradiol receptor activation, respectively, in this masculinization. Beginning at birth, male and female offspring were injected subcutaneously (sc) every other day with either ATD (pre- and neonatal ATD group) or oil vehicle (Flutamide and control groups) until postnatal Day 12. Subjects were gonadectomized as adults, hormonally treated and tested for different behaviors before having their AOS Fos responses to estrous female odors assessed. Prenatal treatment with Flutamide (but not ATD) significantly decreased anogenital distance and severely impaired intromissive and ejaculatory behaviors in males tested after TP replacement without disrupting mounting capacity in either sex. Pre- and neonatal treatment with ATD (but not Flutamide) enhanced lordosis responsiveness in males tested after sc injections of estradiol and progesterone, whereas these perinatal treatments had no effect on any aspect of masculine coital performance in either sex. After TP treatment, male and female control subjects preferred to approach a tethered stimulus female as opposed to a male, and prenatal Flutamide or perinatal ATD treatments did not modify this pattern of partner preference. Neuronal Fos responses to estrous odors were (as in previous studies) identical in the AOS of gonadectomized TP-treated control males and females. Prenatal Flutamide or perinatal ATD treatments failed to disrupt consistently this profile of Fos responses to estrous odors in the AOS of rats of either sex. These behavioral and neuroanatomical findings raise the possibility that the similar level of male-typical responsiveness to social odors that occurs in male and female rats after adult TP treatment results from nonsteroid-hormone-dependent, species-specific factors that act perinatally in the brains of rats of both sexes. [less ▲]

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See detailEnzymatically prepared n-alkyl esters of glucuronic acid: The effect of hydrophobic chain length on surface properties
Blecker, Christophe ULg; Piccicuto, S.; Lognay, Georges ULg et al

in Journal of Colloid & Interface Science (2002), 247(2), 424-428

The effect of hydrophobic chain length on surface properties of enzymatically prepared n-alkyl esters of glucuronic acid are examined. Dynamic parameters from Hua and Rosen's mathematical model and ... [more ▼]

The effect of hydrophobic chain length on surface properties of enzymatically prepared n-alkyl esters of glucuronic acid are examined. Dynamic parameters from Hua and Rosen's mathematical model and equilibrium surface tension are presented for esters with octyl, decyl, dodecyl, and tetradecyl alkyl segments. Increasing the alkyl chain length has a significant influence on the surface activity. Decyl and dodecyl glucuronate exhibit an interesting adsorption speed associated with foaming capacity. Octyl glucuronate exhibits a micellar organization as its bulk concentration is over 10.68 mM. (C) 2002 Elsevier Science (USA). [less ▲]

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See detailLa bibliothèque du Prieuré du Val-Des-Ecoliers à Houffalize : 8 volumes conservés à la Bibliothèque Royale de Belgique
Adam, Renaud ULg

in Archives et Bibliothèques de Belgique = Archief en Bibliotheekwezen in Belgie (2002), 73

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See detailLe médecin du travail face au harcèlement moral au travail : constats et prespectives
Gruslin, Isabelle ULg; Italiano, Patrick ULg; Faulx, Daniel ULg

in Médecine du Travail & Ergonomie= Arbeidsgezondheidszorg & Ergonomie (2002), 39(2), 61-68

L'article de D. Faulx et C. Geuzaine, paru dans le numéro 3-2000 de cette revue, aborde l'étendue du phénomène du harcèlement moral ainsi que les aspects juridiques de la définition, la description du ... [more ▼]

L'article de D. Faulx et C. Geuzaine, paru dans le numéro 3-2000 de cette revue, aborde l'étendue du phénomène du harcèlement moral ainsi que les aspects juridiques de la définition, la description du processus, ses conséquences médicales et les facteurs de risque. Dans la suite de cette étude, nous présentons ici les résultats d'une enquête menée auprès des médecins du travail, en tant que témoins et intervenants privilégiés dans le domaine du harcèlement. Cette enquête vise à apporter des informations descriptives originales concernant les attitudes, les opinions et représentations des médecins du travail par rapport au phénomène de harcèlement moral. En outre, elle est l'occasion de tester une série d'hypothèses sur les facteurs pouvant influencer l'attitude des médecins du travail vis-à-vis du harcèlement moral. [less ▲]

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See detailA randomized comparison of the value of additional stenting after optimal balloon angioplasty for long coronary lesions: final results of the additional value of NIR stents for treatment of long coronary lesions (ADVANCE) study.
Serruys, Patrick W.; Foley, David P.; Suttorp, Martin Jan et al

in Journal of the American College of Cardiology (2002), 39(3), 393-9

OBJECTIVES: We sought to investigate the clinical benefit of additional stent implantation after achieving an optimal result of balloon angioplasty (BA) in long coronary lesions (>20 mm). BACKGROUND: Long ... [more ▼]

OBJECTIVES: We sought to investigate the clinical benefit of additional stent implantation after achieving an optimal result of balloon angioplasty (BA) in long coronary lesions (>20 mm). BACKGROUND: Long coronary lesions are associated with increased early complications and late restenosis after BA. Stenting improves the early outcome, but stent restenosis is also related to both lesion length and stent length. METHODS: A total of 437 patients with a single native lesion 20 to 50 mm in length were included and underwent BA, using long balloons matched to lesion length and vessel diameter (balloon/artery ratio 1.1) to achieve a diameter stenosis (DS) <30% by on-line quantitative coronary angiography (QCA). "Bail-out stenting" was performed for flow-limiting dissections or >50% DS. Patients in whom an optimal BA result was achieved were randomized to additional stenting (using NIR stents) or no stenting. The primary end point was freedom from major adverse cardiac events (MACE) at nine months, and core laboratory QCA was performed on serial angiograms. RESULTS: Bailout stenting was necessary in 149 patients (34%) and was associated with a significantly increased risk of peri-procedural infarction (p < 0.02). Among the 288 randomized patients, the mean lesion length was 27+/-9 mm, and the vessel diameter was 2.78+/-0.52 mm. The procedural success rate was 90% for the 143 patients assigned to BA alone (control group), as compared with 93% in the 145 patients assigned to additional stenting (stent group), which resulted in a superior early minimal lumen diameter (0.54 mm, p < 0.001) and led to reduced angiographic restenosis (27% vs. 42%, p = 0.022). Freedom from MACE at nine months was 77% in both groups. CONCLUSIONS: A strategy of provisional stenting for long coronary lesions led to bailout stenting in one-third of patients, with a threefold increase in peri-procedural infarction. Additional stenting yielded a lower angiographic restenosis rate, but no reduction in MACE at nine months. [less ▲]

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See detailRate coefficient determination in charge transfer reactions
Vaeck, Nathalie; Baloïtcha, Ezinvy; Desouter, Michèle ULg et al

in International Journal of Molecular Sciences (2002), 3

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See detailThe Long Run Performance of Malaysian Initial Public Offerings (IPOs): Value and Growth Effects
Corhay, Albert ULg; Teo, Stanley; Tourani Rad, Alireza

in Managerial Finance (2002), 28(2), 52-64

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See detailA multicenter randomized trial of ketoconazole 2% and zinc pyrithione 1% shampoos in severe dandruff and seborrheic dermatitis.
Pierard, Claudine ULg; Goffin, Véronique ULg; Decroix, Jacques et al

in Skin Pharmacology & Applied Skin Physiology (2002), 15(6), 434-41

Ketoconazole (KET) and zinc pyrithione (ZPT) are compounds active against the Malassezia spp. yeasts, which are believed to play a major role in dandruff and seborrheic dermatitis. We compared the ... [more ▼]

Ketoconazole (KET) and zinc pyrithione (ZPT) are compounds active against the Malassezia spp. yeasts, which are believed to play a major role in dandruff and seborrheic dermatitis. We compared the efficacy and safety of KET 2% and ZPT 1% in shampoo formulations for the alleviation of severe dandruff and seborrheic dermatitis. This open randomized, parallel-group trial began with a 2-week run-in phase during which subjects applied a neutral non-antidandruff shampoo. It was followed by a 4-week randomized treatment phase and a subsequent 4-week follow-up phase without treatment. Shampooing during the treatment period was carried out twice weekly for the KET group and at least twice weekly for the ZPT group in accordance with the label instructions. A total of 343 subjects were recruited to enter the trial. Of the 331 eligible volunteers, 171 were randomized to KET 2% and 160 to ZPT 1%. Clinical assessments were performed. Beneficial effects were evidenced for both medicated shampoos, but the effect was significantly better for KET 2%, which achieved a 73% improvement in the total dandruff severity score compared with 67% for ZPT 1% at week 4 (p < 0.02). The recurrence rate of the disease was also significantly lower following KET 2% treatment than following ZPT 1% treatment. As a consequence, the overall clearing of the skin condition at the end of treatment and follow-up phase was in favor of the KET 2% formulation (p = 0.004). Side effects were minimal. It is concluded that after a 4-week treatment, KET 2% shampoo was significantly superior to ZPT 1% shampoo in the treatment of subjects with severe dandruff or seborrheic dermatitis of the scalp. It is our assumption that this difference is noticeable for the patient and as a consequence relevant. Both formulations were well tolerated. [less ▲]

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See detailDermo-epidermal stimulation elicited by a salicylic acid derivative: a comparison with salicylic acid and all trans-retinoic acid.
Pierard, Gérald ULg; Leveque, J.-L.; Rougier, A. et al

in European Journal of Dermatology (2002), 12(4), -

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See detailLe roman poétique en 1929. Nord, entre fantastique réel et réalisme magique
Denis, Benoît ULg

in Textyles : Revue des Lettres Belges de Langue Française (2002), (21), 31-40

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See detailSulle "mostre" d'organo bergamasche di una grande dinastia di organari del Rinascimento padano: appunti di uno storico dell'arte
Bugini, Mariaelena ULg

in Atti dell'Ateneo di Scienze, Lettere et Arti di Bergamo (2002), a.a 2001/2002

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See detailPrise en compte du bien-être des animaux dans l’aménagement des porcheries : les aspects réglementaires
Nicks, Baudouin ULg; Laitat, Martine ULg; Vandenheede, Marc ULg

in Annales de Médecine Vétérinaire (2002), 146(1), 39-42

A new directive laying down standards for the protection of pigs was published in the Official Journal of the European Communities (directive 2001/88/CE ; OJC 1 Decembre 2001). This directive is amending ... [more ▼]

A new directive laying down standards for the protection of pigs was published in the Official Journal of the European Communities (directive 2001/88/CE ; OJC 1 Decembre 2001). This directive is amending directive 91/630/CEE entered into force in Belgium in 1994. The three main topics refer to : the characteristics of the flooring surfaces, pregnant sows housing and the feeding systems. This paper details and discusses these topics and other points involving modifications of pig housing and management. [less ▲]

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See detailEvidence for a persistent and extensive greening trend in Eurasia inferred from satellite vegetation index data.
Bogaert, Jan ULg; Zhou, L; Tucker, C J et al

in Journal of Geophysical Research (2002), 107(D11),

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See detailPetite réflexion sur la qualité du bois d'épicéa
Hebert, Jacques ULg; Herman, Marc; Jourez, Benoît ULg

in Forêt Wallonne (2002), (60), 24-25

En termes de qualité du bois, l'influence du sylviculteur est déterminante. En effet, dès la décision de plantation, et ensuite, par le jeu des soins culturaux et des éclaircies, il va façonner, compte ... [more ▼]

En termes de qualité du bois, l'influence du sylviculteur est déterminante. En effet, dès la décision de plantation, et ensuite, par le jeu des soins culturaux et des éclaircies, il va façonner, compte tenu des conditions environnementales, les caractéristiques de la matière première qui en définiront les aptitudes technologiques. [less ▲]

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See detailLa réalité morale du sociologue : le cognitivisme de Raymond Boudon
Jacquemain, Marc ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (2002), 94-95-96

Raymond Boudon defends that the social actor holds overall rational beliefs : we have "good reasons" for most of our beliefs. But he also defends the idea that those "good reasons" can lead to "moral ... [more ▼]

Raymond Boudon defends that the social actor holds overall rational beliefs : we have "good reasons" for most of our beliefs. But he also defends the idea that those "good reasons" can lead to "moral truths". How then can he avoid pure platonism (the idea that "values" exist objectively in a world of their own) ? When confronting to to the task of defending through concrete examples how we can differentiate "good reasons" from bad ones, he says that good reasons are widely shared. But then the idea of objectivity of values dissolves in a loose theory of opinion, that's to say "doxa", which is the very contrary of platonic ideas. So the intent to point to "objective" values seems to lead either to pure dogmatism or to pure relativism. [less ▲]

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See detailUtilisation de la ropivacaine par voie peridurale pour l'analgesie postoperatoire.
Senard, Marc ULg; Joris, Jean ULg

in Annales Françaises d'Anesthésie et de Réanimation (2002), 21(9), 713-24

OBJECTIVES: To describe pharmacology and toxicology of ropivacaine. To assess the clinical efficacy of ropivacaine when used for postoperative epidural analgesia and to provide recommendations for ... [more ▼]

OBJECTIVES: To describe pharmacology and toxicology of ropivacaine. To assess the clinical efficacy of ropivacaine when used for postoperative epidural analgesia and to provide recommendations for clinical practice. DATA SOURCES: Search in the Medline data base of original articles in French and English published since 1995, using the following key words: ropivacaine, postoperative analgesia, epidural, caudal block. STUDY SELECTION: Prospective randomised studies in adults and children were selected. Letters to editors and editorials were excluded. DATA EXTRACTION: Articles have been analyzed: to determine the dose of ropivacaine required for postoperative epidural analgesia, to assess the benefits of combination of epidural ropivacaine and additives (opioids or other), to compare epidural ropivacaine and bupivacaine and to assess the use of ropivacaine via caudal route for paediatric postoperative analgesia. DATA SYNTHESIS: 20 mg h-1 of ropivacaine is required to provide effective analgesia. This dose produces a motor block in a significant number of patients. Combination with an opioid allows for a reduction in ropivacaine requirement and subsequently in the incidence of motor blockade. In adults, equipotency ratio of ropivacaine and bupivacaine varies between 1.5/1 and 1/1 depending upon the concentration used. At equipotent doses, early postoperative mobilisation is facilitated with ropivacaine. In case of paediatric caudal analgesia, this ratio is close to 1. CONCLUSIONS: Epidural ropivacaine combined with opioid provide good postoperative pain relief. Reduction in the incidence of motor blockade and safe toxicological profile make this local anaesthetic a suitable alternative of bupivacaine for postoperative epidural analgesia. [less ▲]

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See detailDifferential sensitivity of two insect GABA-gated chloride channels to dieldrin, fipronil and picrotoxinin
Le Corronch, Hervé; Alix, Philippe ULg; Hue, B

in Journal of Insect Physiology (2002), 48

In the central nervous system of both vertebrates and invertebrates inhibitory neurotransmission is mainly achieved through activation of gamma-aminobutyric acid (GABA) receptors. Extensive studies have ... [more ▼]

In the central nervous system of both vertebrates and invertebrates inhibitory neurotransmission is mainly achieved through activation of gamma-aminobutyric acid (GABA) receptors. Extensive studies have established the structural and pharmacological properties of vertebrate GABA receptors. Although the vast majority of insect GABA-sensitive responses share some properties with vertebrate GABAA receptors, peculiar pharmacological properties of these receptors led us to think that several GABA-gated chloride channels are present in insects. We describe here the pharmacological properties of two GABA receptor subtypes coupled to a chloride channel on dorsal unpaired median (DUM) neurones of the adult male cockroach. Long applications of GABA induce a large biphasic hyperpolarization, consisting of an initial transient hyperpolarization followed by a slow phase of hyperpolarization that is not quickly desensitized. With GABA, the transient hyperpolarization is sensitive to picrotoxinin, fipronil and dieldrin whereas the slow response is insensitive to these insecticides.When GABA is replaced by muscimol and cis-4-aminocrotonic acid (CACA) a biphasic hyperpolarization consisting of an initial transient hyperpolarization followed by a sustained phase is evoked which is blocked by picrotoxinin and fipronil. Exposure to dieldrin decreases only the early phase of the muscimol and CACA-induced biphasic response, suggesting that two GABA-gated chloride channel receptor subtypes are present in DUM neurones. This study describes, for the first time, a dieldrin resistant component different to the dieldrin- and picrotoxinin-resistant receptor found in several insect species. [less ▲]

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See detailEnergy Partitioning Between Latent And Sensible Heat Flux During The Warm Season At Fluxnet Sites
Wilson, Kell B.; Baldocchi, Dennis D.; Aubinet, Marc ULg et al

in Water Resources Research (2002), 38(12),

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See detailGestion de l’information dans les pratiques de soins intégrés
Prevost, Marianne; Della Giustina, Vanni; Gosselain, Yves et al

in Santé Conjuguée (2002), 19

Gestion de l’information dans les pratiques de soins intégrés, autrement dit, GIPSI : tel était le thème d’un forum organisé le 15 décembre 2001 à Natoye par la Fédération des maisons médicales, lequel a ... [more ▼]

Gestion de l’information dans les pratiques de soins intégrés, autrement dit, GIPSI : tel était le thème d’un forum organisé le 15 décembre 2001 à Natoye par la Fédération des maisons médicales, lequel a rassemblé une bonne soixantaine de participants issus de trente et une maisons médicales. L’information, c’est un élément clé pour tous les soignants, toutes les équipes : les pratiques de soins reposent sur, et génèrent, une foule d’informations de tous ordres, qu’il n’est pas toujours aisé de rassembler, de trier, d’exploiter à bon escient… comment organiser le recueil et l’analyse de toutes les informations utiles pour améliorer le bien-être des patients – et des soignants ? Quels systèmes d’information peuvent-ils faire gagner du temps, s’intégrer de manière souple dans le travail quotidien, sans poser trop de difficultés nouvelles ? Comment mieux communiquer entre soignants, entre soignants et patients ? Clarifier les questions relatives au partage de l’information, la transmission, la confidentialité ? [less ▲]

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See detailDonnées actuelles sur la toxicité de l'oxygène
Deby, Ginette ULg; Deby, C.; Lamy, Maurice ULg

in Réanimation (2002), 11(1), 28-39

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See detailBudesonide in Collagenous colitis: A Double-Blind Placebo-Controlled Trial With Histologic Follow-Up
Baert, Filip; Schmit, Alain; D'Haens, Geert et al

in Gastroenterology (2002), 122

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See detail- La bande dessinée muette et le texte
Paques, Frédéric ULg

in Art&Fact (2002), 21

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See detailLa rente et la galette : à propos du remboursement anticipé d’un crédit
Vanbrabant, Bernard ULg

in Revue du Notariat Belge (2002)

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See detailInfiltrative lipoma in the foreleg of a horse
Olle, Edwin; Saunders, Jimmy; Desmecht, Daniel ULg

in Vlaams Diergeneeskundig Tijdschrift (2002), 71

This case report describes an infiltrative lipoma in a horse. A slow-growing mass, detected early afterbirth, was present at the caudal aspect of the foreleg (antebrachium) of a 2-year-old gelding ... [more ▼]

This case report describes an infiltrative lipoma in a horse. A slow-growing mass, detected early afterbirth, was present at the caudal aspect of the foreleg (antebrachium) of a 2-year-old gelding. Cytological fea-tures were that of a benign lipoma. Surgical resection was attempted but failed due to the infiltrative natureof the mass. Consequently, the horse was euthanized. Histopathology revealed an infiltrative lipoma. Thistumor is histologically benign but surgical resection is usually impossible due to its infiltrative nature. [less ▲]

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See detailPositron emission tomography in non-Hodgkin's lymphoma (NHL): relationship between tracer uptake and pathological findings, including preliminary experience in the staging of low-grade NHL.
Jerusalem, Guy ULg; Beguin, Yves ULg

in Clinical Lymphoma (2002), 3(1), 56-61

Advances in imaging techniques have allowed more precise staging and better evaluation of the effect of new treatment modalities. The limitations of conventional morphologic imaging techniques are well ... [more ▼]

Advances in imaging techniques have allowed more precise staging and better evaluation of the effect of new treatment modalities. The limitations of conventional morphologic imaging techniques are well known. Positron emission tomography (PET) using fluorine-18-labeled fluorodeoxyglucose is now routinely used for initial staging and re-evaluation during or after treatment of Hodgkin's disease and aggressive non-Hodgkin's lymphoma (NHL), but not in low-grade NHL. In the first part of this review, the relationship between glucose metabolism as measured by PET, pathological findings including histological grade and proliferative activity, and prognosis are analyzed. In the second part, the potential role of PET in the staging and follow-up of low-grade NHL is discussed. Published data indicate that PET may contribute to the management of low-grade follicular NHL. [less ▲]

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See detailEvaluation of ocean model ventilation with CFC-11: comparison of 13 global ocean models
Dutay, J.-C.; Bullister, J. L.; Doney, S. C. et al

in Ocean Modelling (2002), 4(2), 89-120

We compared the 13 models participating in the Ocean Carbon Model Intercomparison Project (OCMIP) with regards to their skill in matching observed distributions of CFC-11. This analysis characterizes the ... [more ▼]

We compared the 13 models participating in the Ocean Carbon Model Intercomparison Project (OCMIP) with regards to their skill in matching observed distributions of CFC-11. This analysis characterizes the abilities of these models to ventilate the ocean on timescales relevant for anthropogenic CO2 uptake. We found a large range in the modeled global inventory (+/- 30\%), mainly due to differences in ventilation from the high latitudes. In the Southern Ocean, models differ particularly in the longitudinal distribution of the CFC uptake in the intermediate water, whereas the latitudinal distribution is mainly controlled by the subgrid-scale parameterization. Models with isopycnal diffusion and eddy-induced velocity parameterization produce more realistic intermediate water ventilation. Deep and bottom water ventilation also varies substantially between the models. Models coupled to a sea-ice model systematically provide more realistic AABW formation source region; however these same models also largely overestimate AABW ventilation if no specific parameterization of brine rejection during sea-ice formation is included. In the North Pacific Ocean, all models exhibit a systematic large underestimation of the CFC uptake in the thermocline of the subtropical gyre, while no systematic difference toward the observations is found in the subpolar gyre. In the North Atlantic Ocean, the CFC uptake is globally underestimated in subsurface. In the deep ocean, all but the adjoint model, failed to produce the two recently ventilated branches observed in the North Atlantic Deep Water (NADW). Furthermore, simulated transport in the Deep Western Boundary Current (DWBC) is too sluggish in all but the isopycnal model, where it is too rapid. (C) 2002 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailPositional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition
Grisart, B.; Coppieters, Wouter ULg; Farnir, Frédéric ULg et al

in Genome Research (2002), 12(2), 222-231

We recently mapped a quantitative trait locus (QTL) with a major effect on milk composition-particularly fat content-to the centromeric end of bovine chromosome 14. We subsequently exploited linkage ... [more ▼]

We recently mapped a quantitative trait locus (QTL) with a major effect on milk composition-particularly fat content-to the centromeric end of bovine chromosome 14. We subsequently exploited linkage disequilibrium to refine the map position of this QTL to a 3-cM chromosome interval bounded by microsatellite markers BULGE13 and BULGE09. We herein report the positional candidate cloning of this QTL, involving (I) the construction of a BAC contig spanning the corresponding marker interval, (2) the demonstration that a very strong candidate gene, acylCoA:diacylglycerol acyltransferase (DGATf), maps to that contig, and (3) the identification of a nonconservative K232A substitution in the DGAT1 gene with a major effect on milk fat content and other milk characteristics. [less ▲]

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See detailInfluence de l'hérédité, du sexe et de la saison sur le type d'épisode dans le trouble bipolaire.
Mortazi, M.; Bertrand, Jean-Marie ULg; Triffaux, Jean-Marc ULg et al

in Revue Médicale de Liège (2002), 57(3), 171-5

The aim of this work was to investigate if sex, age, family history, season and hypothyroidism have any influence on the type of episodes (manic, depressive, mixed) seen in bipolar patients. This ... [more ▼]

The aim of this work was to investigate if sex, age, family history, season and hypothyroidism have any influence on the type of episodes (manic, depressive, mixed) seen in bipolar patients. This retrospective study concerns a sample of 208 patients with a diagnosis of bipolar disorder (type I or II), who were admitted in one of two psychiatric centers between July 1996 and June 2000. The sex-ratio was 2.8 females for 1 male. Sex, family history and hypothyroidism were not associated with any type of episode. A higher percentage of depressive episodes was observed in the patients who were older than 50 and the average age of depressive patients was higher than that of other patients. There was no seasonal pattern in this study and the season did not influence the type of episode. The results indicate no influence of sex, season, family history and hypothyroidism on the type of episode presented. On the opposite, age seems to favour depression episode. [less ▲]

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See detailPsychologie et histoire : une réflexion à double sens
Richelle, Marc ULg

in Anuario de Psicologia (2002), 33(2), 231-247

This reflection on the relations between psychology and history addresses four distinct issues. The first is the history of psychology: the importance of reference to the past, even if only to put current ... [more ▼]

This reflection on the relations between psychology and history addresses four distinct issues. The first is the history of psychology: the importance of reference to the past, even if only to put current research and theory into perspective. Second, the essential historical dimension of human is presented as a crucial aspect in defining the very object of psychological science; the "historical psychology" approach, specifically its French variety as represented by Ignace Meyerson's legacy, is breifly discussed. Third, the contribution of psychology to the work of historians is considered. Finally, the joint involvement of both psychology and history in contemporary society is discussed with reference to the use (and abuse) of history in the construction of collective identity and to the claims for repair for offenses and damages made in the past, echoed by the declarations of guilt on the part of their perpetrators, on more exactly their descendants. These issues are discussed in the light of psychological approaches to memory and forgetting. [less ▲]

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See detailComparaison des cahiers des charges de filières de production porcine sous « signe de qualité » en Région wallonne.
Degre, Aurore ULg; Verheve, Didier; Debouche, Charles ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2002), 6(4), 221-230

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See detailExistence de karsts en roches cristallines silicatées non carbonatées en Afrique sahélienne et équatoriale, implications hydrogéologiques
Willems, Luc ULg; Pouclet, André; Vicat, Jean-Paul

in Bulletin de la Société Géologique de France (2002), 173(4), 337-345

Various cavities studied in western Niger and South Cameroon show the existence of important karstic phenomena into metagabbros and gneisses. These large-sized eaves resulted from generalized dissolution ... [more ▼]

Various cavities studied in western Niger and South Cameroon show the existence of important karstic phenomena into metagabbros and gneisses. These large-sized eaves resulted from generalized dissolution of silicate formations in spite of their low solubility. Karstification is produced by deep hydrous transfer along lithological discontinuities and fracture net works. The existence of such caves has major implications in geomorphology, under either Sahelian and Equatorial climate, and in hydrogeology and water supply, particularly in the Sahel area. [less ▲]

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See detailFirst-principles computation of material properties: the ABINIT software project
Gonze, X.; Beuken, J. M.; Caracas, R. et al

in Computational Materials Science (2002), 25(3), 478-492

The density functional theory (DFT) computation of electronic structure, total energy and other properties of materials, is a field in constant progress. In order to stay at the forefront of knowledge, a ... [more ▼]

The density functional theory (DFT) computation of electronic structure, total energy and other properties of materials, is a field in constant progress. In order to stay at the forefront of knowledge, a DFT software project can benefit enormously from widespread collaboration, if handled properly. Also, modern software engineering concepts can considerably ease its development. The ABINIT project relies upon these ideas: freedom of sources, reliability, portability, and self-documentation are emphasised, in the development of a sophisticated plane-wave pseudopotential code. We describe ABINITv3.0, distributed under the GNU General Public License. The list of ABINITv3.0 capabilities is presented, as well as the different software techniques that have been used until now: PERL scripts and CPP directives treat a unique set of FORTRAN90 source files to generate sequential (or parallel) object code for many different platforms; more than 200 automated tests secure existing capabilities; strict coding rules are followed; the documentation is extensive, including online help files, tutorials, and HTML-formatted sources. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailHepatic insulin resistance in obese non-diabetic subjects and in type 2 diabetic patients.
Paquot, Nicolas ULg; Scheen, André ULg; Dirlewanger, Mirjam et al

in Obesity Research (2002), 10(3), 129-34

OBJECTIVE: Obese non-diabetic patients are characterized by an extra-hepatic insulin resistance. Whether obese patients also have decreased hepatic insulin sensitivity remains controversial. RESEARCH ... [more ▼]

OBJECTIVE: Obese non-diabetic patients are characterized by an extra-hepatic insulin resistance. Whether obese patients also have decreased hepatic insulin sensitivity remains controversial. RESEARCH METHODS AND PROCEDURES: To estimate their hepatic insulin sensitivity, we measured the rate of exogenous insulin infusion required to maintain mildly elevated glycemia in obese patients with type 2 diabetes, obese non-diabetic patients, and lean control subjects during constant infusions of somatostatin and physiological low-glucagon replacement infusions. To account for differences in insulin concentrations among the three groups of subjects, an additional protocol was also performed in healthy lean subjects with higher insulin infusion rates and exogenous dextrose infusion. RESULTS: The insulin infusion rate required to maintain glycemia at 8.5 mM was increased 4-fold in obese patients with type 2 diabetes and 1.5-fold in obese non-diabetic patients. The net endogenous glucose production (measured with 6,6-(2)H(2)-glucose) and total glucose output (measured with 2-(2)H(1)-glucose) were approximately 30% lower in the patients than in the lean subjects. Net endogenous glucose production and total glucose output were both markedly increased in both groups of obese patients compared with lean control subjects during hyperinsulinemia. DISCUSSION: Our data indicate that both obese non-diabetic and obese type 2 diabetic patients have a blunted suppressive action of insulin on glucose production, indicating hepatic and renal insulin resistance. [less ▲]

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See detailThe value of serologic markers in indeterminate colitis: A prospective follow-up study
Joossens, S.; Van Steen, Kristel ULg; Vermeire, S. V. et al

in Gastroenterology (2002), 122(5), 1242-1247

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See detailThe role of aminosalicylates in the treatment of ulcerative colitis.
Van Assche, Gert; Baert, Filip; De Reuck, Marc et al

in Acta Gastro-Enterologica Belgica (2002), 65(4), 196-9

Aminosalicylates (5-ASA, sulfasalazine and mesalazine) play a central role in the treatment of ulcerative colitis (UC). For acute treatment of mild to moderate flares and in maintenance treatment, their ... [more ▼]

Aminosalicylates (5-ASA, sulfasalazine and mesalazine) play a central role in the treatment of ulcerative colitis (UC). For acute treatment of mild to moderate flares and in maintenance treatment, their efficacy has been established. Since ulcerative colitis is limited to the distal colon in two thirds of the patients, topical therapy also plays an important role. In mild/moderate active disease 5-ASA 4 g/d is as effective as oral corticosteroids. Ulcerative proctitis is treated with 2 x 500 mg or 1 x 1 g suppositories and proctosigmoiditis with 1 to 4 g enemas. Oral 5-ASA is also safe in maintenance treatment and is generally well tolerated. The risk of colorectal tumours is increased in patients with longstanding ulcerative colitis and epidemiological evidence indicates that chronic 5-ASA treatment reduces this risk. However, at present there is insufficient evidence to maintain patients on life-long 5-ASA maintenance treatment for this indication. [less ▲]

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See detailL'égalité et le droit commercial: un rapport à géométrie variable
Thirion, Nicolas ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2002)

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See detailRéanimation cardiopulmonaire chez la femme enceinte
Brichant, Jean-François ULg; Dewandre, Pierre-Yves ULg; Bonhomme, Vincent ULg et al

in Praticien en Anesthésie Réanimation (Le) (2002), 6

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See detailEchographie de l’appareil podotrochléaire : étude in vitro sur 30 membres isolés de cheval
Busoni, Valeria ULg; Méan, Marie-Noël; Brignone, Luca et al

in Annales de Médecine Vétérinaire (2002), 146(3), 181-187

Thirty equine isolated limbs have been examined by ultrasonography (7.5 MHz probes) using the frog as acoustic window. The aims of the study were to establish the ultrasonographic anatomy of the distal ... [more ▼]

Thirty equine isolated limbs have been examined by ultrasonography (7.5 MHz probes) using the frog as acoustic window. The aims of the study were to establish the ultrasonographic anatomy of the distal portion of the deep digital flexor tendon, to determine the capability to visualize podotrochlear bursa and flexor surface fibrocartilage by ultrasound and to evaluate the sensitivity of ultrasonography for the assessment of flexor surface abnormalities. Because of the relative orientation of the ultrasound beam and the deep digital flexor tendon fibers, this tendon always appears hypoechogenic on transcuneal ultrasonographic images. The flexor surface fibrocartilage is difficult to see if the podotrochlear bursa is not injected. The thickness of the normal bursa is negligible at the palmar aspect of the distal sesamoid bone. Sensitivity of ultrasonography for the detection of flexor surface irregularities was high (90,91%), sensitivity was 84,21%. Ultrasonography using the transcuneal approach could be an useful adjunct to routine radiographic examination of the foot in the assessment of flexor surface irregularities. [less ▲]

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See detailCharacterization Of Kenyan Isolates Of Fusarium Udum From Pigeonpea [Cajanus Cajan (L.) Millsp.] By Cultural Characteristics, Aggressiveness And Aflp Analysis
Kiprop, E. K.; Baudoin, Jean-Pierre ULg; Mwang'Ombe, A. W. et al

in Journal of Phytopathology-Phytopathologische Zeitschrift (2002), 150

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See detailComment je traite ... la paralysie faciale par anastomose hypoglosso-faciale.
Courtmans, I; Born, J D; CARLIER, Alain ULg et al

in Revue Médicale de Liège (2002), 57(1), 3-6

Thirteen patients underwent a hypoglosso- or a spino-facial nerve anastomosis between 1990 and 1996. Facial palsy was the result of surgery in 12 cases and of radiosurgery in 1 case. The mean interval ... [more ▼]

Thirteen patients underwent a hypoglosso- or a spino-facial nerve anastomosis between 1990 and 1996. Facial palsy was the result of surgery in 12 cases and of radiosurgery in 1 case. The mean interval between facial palsy and anastomosis was 12 months. Facial nerve function is determined on the basis of clinical examination according to the classification of House-Brackmann and our own evaluation. According to House, 10 patients are classified grade III and 3 grade IV. Our evaluation defines in 10 grade III, 7 good results and 3 fair results. As far as the good results are concerned, the mean interval between palsy and anastomosis is short (< 3 months). The permanent eating and swallowing dysfunctions are consecutive to multiple cranial nerve deficits. The post-paralysis hemifacial spasm is facilitated by prolongated electric stimulations. [less ▲]

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See detailContribution à l'étude de la qualité bactériologique des eaux de surface à vocation touristique en Wallonie (Belgique)
Rosillon, Françis ULg; Culot, Marc ULg; Bosser, C. et al

in Cahiers de l'association scientifique européenne pour l'eau et la santé (2002), 7(1), 3-13

Au cours de la saison estivale 2000 et 2001, 33 zones récréatives en cours d'eau ont fait l'objet d'un suivi de la qualité bactériologique. Au-delà d'une simple surveillance, un profil de zone a été ... [more ▼]

Au cours de la saison estivale 2000 et 2001, 33 zones récréatives en cours d'eau ont fait l'objet d'un suivi de la qualité bactériologique. Au-delà d'une simple surveillance, un profil de zone a été établi. Celui-ci consiste à identifier et à hiérarchiser l'importance des sources de contamination fécale pouvant influencer la zone récréative. Lors d'événements pluvieux, une dégradation plus importante de la qualité des eaux a pu être mise en évidence. La diversité des sources de contamination implique une démarche multi-acteurs. A des actions ponctuelles de remédiation, s'ajoutent des mesures préventives d'accompagnement au sein de périmètres de protection. Une meilleure connaissance de la dynamique des germes fécaux dans le milieu naturel et du phénomène d'auto-épuration bactérienne devrait permettre de mieux définir les limites de ces périmètres de protection [less ▲]

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See detailEvaluation de la composition de la carcasse et de la qualité de la viande par ultrasonographie chez le porc
Youssao, A. K. L.; Verleyen, Vincent ULg; Leroy, Pascal ULg

in Annales de Médecine Vétérinaire (2002), 146(1), 19-29

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See detailLa critique historique: méthode ou théorie de l'histoire? Libres propos en faveur du constructivisme
Havelange, Carl ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (2002), 94-95-96

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See detailChoice of probing site for estimation of carcass lean percentage in Piétrain pig using the real-time ultrasound
Youssao, A. K. L.; Verleyen, Vincent ULg; Michaux, Charles ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2002), 6(4), 195-200

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See detailIn situ dynamic analysis of solid or aqueous solutions undergoing chemical reactions by RBS or PIXE with external beam
Bouquillon, A.; Dran, J*-C; Lagarde, G. et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2002), 188

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See detailSingle step synthesis of metal catalysts supported on porous carbon with controlled texture
Job, Nathalie ULg; Ferauche, fabrice; Pirard, René ULg et al

in Studies in Surface Science and Catalysis (2002), 143

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See detailImportance of pedogenic factors in the spatial distribution of some soils properties in the Belgian Loess Belt: II. Some loess-substratum contacts
Colinet, Gilles ULg; Lacroix, Daniel ULg; Bock, Laurent ULg

in Aardkundige Mededelingen (2002), 12

The geochemical influence of parent material on soil content in some metallic trace elements (MTE) is studied in the Belgian loess belt. The first results show straight sharp Transitions between loess and ... [more ▼]

The geochemical influence of parent material on soil content in some metallic trace elements (MTE) is studied in the Belgian loess belt. The first results show straight sharp Transitions between loess and substratum. This leads to the conclusion that most soils should have the same range of natural values of MTE content. [less ▲]

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See detailUreteral endometriosis: a complication of rectovaginal endometriotic (adenomyotic) nodules
Donnez, Jacques; NISOLLE, Michelle ULg; Squifflet, Jean

in Fertility and Sterility (2002), 77(1), 32-37

Objective: To present data from 18 cases of ureteral endometriosis. Design: Prospective clinical study. Setting: Department of gynecology at a university hospital. Patient(s): Four hundred and five ... [more ▼]

Objective: To present data from 18 cases of ureteral endometriosis. Design: Prospective clinical study. Setting: Department of gynecology at a university hospital. Patient(s): Four hundred and five patients with severe dysmenorrhea or deep dyspareunia due to a rectovaginal endometriotic (adenomyotic) nodule. Intervention(s): Patients were prospectively evaluated using intravenous pyelography. All patients underwent laparoscopic surgery to remove rectovaginal adenomyosis and ureterolysis. Main Outcome Measure(s): Presurgical and postsurgical evaluation and histologic analysis. Result(s): Preoperative intravenous pyelography revealed ureteral stenosis with ureterohydronephrosis in 18 patients (4.4%). A significantly higher prevalence (11.2%) was observed in nodules ≥ 3 cm in diameter. Five women (20%) had complete ureteral stenosis. Kidney scintigraphy revealed damaged kidney parenchymal function, which ranged from 18% to 42%. Laparoscopic ureterolysis was done in 16 women; 2 women underwent ureteral resection and uretero-ureterostomy. A significant postoperative decrease in ureterohydronephrosis was noted in all patients; however, renal function improved only slightly. Conclusion(s): Ureteral endometriosis was found in 4.4% of patients with rectovaginal endometriotic (adenomyotic) nodules. Ureterolysis and removal of associated adenomyotic lesions was sufficient therapy in most patients; two required resection of the ureteral stenotic segment. Intravenous pyelography should be performed in all women with rectovaginal nodules ≥ 3 cm to prevent nonreversible loss of renal function. [less ▲]

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See detailEcology of Salmonella in slaughter pigs digestive tract and study of the contamination of carcasses
Boudry, Christelle ULg; Korsak Koulagenko, Nicolas ULg; Jacob, Benoit et al

in Annales de Médecine Vétérinaire (2002), 146(6, DEC-JAN), 353-360

This article presents a study on the Salmonella asymptomatic carriage of finishing pigs and its consequences on the contamination of carcasses. Twenty finishing pigs were followed to determine the faecal ... [more ▼]

This article presents a study on the Salmonella asymptomatic carriage of finishing pigs and its consequences on the contamination of carcasses. Twenty finishing pigs were followed to determine the faecal shedding of Salmonella. No sample was positive but at the slaughterhouse, the analysis of tonsils and certain parts of the digestive tract (mesenterial lymph nodes, ileum and large intestine content) revealed that 70% of the pigs were positive. The strains isolated from the faecal samples of the large intestine and from tonsils were identical, which might indicate that there has been an oral contamination from pig to pig due to the shedding of Salmonella or a carriage of different strains in different organs. The mesenterial lymph nodes (40 % positive) were contaminated by strains which were different from those from the faecal samples and tonsils. Salmonella strains were only found on the swabs of one carcass. A complementary assay has shown the negative role played by the scalding step. This latter may contaminate the oral and rectal cavities of slaughtered animals. This entire study reveals the difficulty to predict the contamination risk at the slaughterhouse from the analysis of finishing pigs faecal samples. Therefore, a better knowledge of the carriage and the shedding of Salmonella during the finishing period and during the slaughter is necessary to minimise meat contamination. [less ▲]

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See detailInitiation à une pédagogie active de l'éveil scientifique : analyse d'une démarche d'observation en formation continuée d'enseignants
Geurden, Christine; Hanck, Marianne; Giot, Bernadette ULg et al

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2002), 9-10

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See detailFurther evidence on the relationship between dopamine and novelty seeking: a neuroendocrine study
Hansenne, Michel ULg; Pinto, Emmanuel ULg; Pitchot, William ULg et al

in Personality & Individual Differences (2002), 33(6), 967-977

In the biosocial model of Cloninger, three major personality dimensions, novelty seeking (NS), harm avoidance (HA), and reward dependence (RD) are dependent on central monoaminergic systems, respectively ... [more ▼]

In the biosocial model of Cloninger, three major personality dimensions, novelty seeking (NS), harm avoidance (HA), and reward dependence (RD) are dependent on central monoaminergic systems, respectively dopaminergic, serotonergic, and noradrenergic. This study investigated the relationships between these major personality dimensions and growth hormone (GH) responses to both apomorphine and clonidine challenge tests in healthy subjects. GH responses to apomorphine were significantly correlated with NS when peak relative values were considered (r=0.47, P=0.03). HA and RD did not show any relationships with the endocrine responses. In contrast, no significant relationship existed between GH responses to clonidine and any of the three temperament dimensions. These results gave another support of the hypothesized link between NS and dopaminergic central neurotransmission. In contrast, the results did not confirm the association between RD and noradrenergic central neurotransmission, probably because RD is poorly validated. This partial confirmation might suggest that the link between personality traits and neurotransmission systems is probably indirect. (C) 2002 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailUn incunable de la bibliothèque de Liévin Torrentius (1525-1595) retrouvé (Bruxelles, Bibliothèque Royale, Réserve Précieuse, INC B 1192)
Adam, Renaud ULg

in Bulletin de la Société Royale Le Vieux-Liège (2002), 14(11-12), 335-337

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See detailL’arrêt n°41/2002 de la Cour d’arbitrage : de la notion constitutionnelle de droit politique à la notion de "droit civil" au sens de la Convention européenne des droits de l’homme
Rosoux, Géraldine ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2002)

The article analyzes the impact of the conventional concept of "civil right" (art. 6 E.C.H.R.) on the constitutional distinction between civil and political rights (art. 144-145 Const.).

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See detailLe métabolisme du fer
Beguin, Yves ULg

in Hématologie (2002), 8

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See detailLa dignité humaine comme concept juridique
Fierens, Jacques ULg

in Journal des Tribunaux (2002)

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See detailPistes de réflexion pour développer, à l’école, les compétences de tous les élèves
Beckers, Jacqueline ULg

in L’École valdôtaine (2002), 55

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See detailLes contes de Grimm: présentation de quelques inconnus en français qui témoignent de l'entrée des Contes de l'Enfance et du Foyer dans la littérature de jeunesse
Delbrassine, Daniel ULg

in Cahiers du CLPCF (2002), 2

Présentation et traduction de contes retranchés dans le recueil des Grimm

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See detailFactor XIII a-positive dermal dendrocytes and shear wave propagation in human skin.
Hermanns-Lê, Trinh ULg; Uhoda, I.; Pierard, Claudine ULg et al

in European Journal of Clinical Investigation (2002), 32(11), 847-51

BACKGROUND: The in vivo interdependence between the phenotypic characteristics of dermal cells and the strain imposed on the tissue has not been studied thoroughly in humans. In particular the mechanical ... [more ▼]

BACKGROUND: The in vivo interdependence between the phenotypic characteristics of dermal cells and the strain imposed on the tissue has not been studied thoroughly in humans. In particular the mechanical force modulation of Factor XIII a expression in dermal dendrocytes (DD) remains unknown. MATERIALS AND METHODS: The present study compares the numerical density of Factor XIII a-positive DD and the in vivo shear wave velocity in the skin. The investigation was performed in 20 men of normal weight and 20 obese men before and after entering a slimming process. RESULTS: Excess cutaneous fat places the skin under increased intrinsic tension. The resonance running time measurement (RRTM) and the DD density were significantly reduced in overweight individuals. After a short-term but intense slimming process, the same individuals showed a trend to normalization of these two parameters without, however, reaching significance. Pooling all data yielded a significant logarithmic correlation between RRTM values and densities in Factor XIII a-positive DD. CONCLUSION: Factor XIII a expression in human DD may be partially regulated by the intrinsic resting tensions in the skin. [less ▲]

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See detailFatty Acid Hydroperoxides Biotransformation By Potato Tuber Cell-Free Extracts
Fauconnier, Marie-Laure ULg; Delcarte, J.; Jaziri, M. et al

in Journal of Plant Physiology (2002), 159(10),

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See detailEtude longitudinale de l'hémodynamique artérielle mésentérique chez le nouveau-né prématuré stable en alimentation entérale
Battisti, Oreste ULg; Withofs, L.; Adant-François, A. et al

in Louvain Medical (2002), 121

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See detailIconographies de saints mosans : Liège, ULG Wittert 82
George, Philippe ULg

in Bulletin de la Société Royale Le Vieux-Liège (2002)

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See detailThe gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man
Marion, Evelyne; Kaisaki, Pamela Jane; Pouillon, Valérie et al

in Diabetes (2002), 51

Genetic susceptibility to type 2 diabetes involves many genes, most of which are still unknown. The lipid phosphatase SHIP2 is a potent negative regulator of insulin signaling and sensitivity in vivo and ... [more ▼]

Genetic susceptibility to type 2 diabetes involves many genes, most of which are still unknown. The lipid phosphatase SHIP2 is a potent negative regulator of insulin signaling and sensitivity in vivo and is thus a good candidate gene. Here we report the presence of SHIP2 gene mutations associated with type 2 diabetes in rats and humans. The R1142C mutation specifically identified in Goto-Kakizaki (GK) and spontaneously hypertensive rat strains disrupts a potential class II ligand for Src homology (SH)-3 domain and slightly impairs insulin signaling in cell culture. In humans, a deletion identified in the SHIP2 3' untranslated region (UTR) of type 2 diabetic subjects includes a motif implicated in the control of protein synthesis. In cell culture, the deletion results in reporter messenger RNA and protein overexpression. Finally, genotyping of a cohort of type 2 diabetic and control subjects showed a significant association between the deletion and type 2 diabetes. Altogether, our results show that mutations in the SHIP2 gene contribute to the genetic susceptibility to type 2 diabetes in rats and humans [less ▲]

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See detailOntología y fenomenología en el pensamiento de Saussure
Badir, Sémir ULg

in Topicos del Seminario (2002), 8

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See detailGeneration of a finite element MESH from stereolithography (STL) files
Béchet, Eric ULg; Cuilliere, Jean-Christophe; Trochu, François

in Computer-Aided Design (2002), 34(1), 1-17

The aim of the method proposed here is to show the possibility of generating adaptive surface meshes suitable for the finite element method, directly from an approximated boundary representation of an ... [more ▼]

The aim of the method proposed here is to show the possibility of generating adaptive surface meshes suitable for the finite element method, directly from an approximated boundary representation of an object created with CAD software. First, we describe the boundary representation, which is composed of a simple triangulation of the surface of the object. Then we will show how to obtain a conforming size-adapted mesh. The size adaptation is made considering geometrical approximation and with respect to an isotropic size map provided by an error estimator. The mesh can be used "as is" for a finite element computation (with shell elements), or can be used as a surface mesh to initiate a volume meshing algorithm (Delaunay or advancing front). The principle used to generate the mesh is based on the Delaunay method, which is associated with refinement algorithms, and smoothing. Finally, we will show that not using the parametric representation of the geometrical model allows us to override some of the limitations of conventional meshing software that is based on an exact representation of the geometry. (C) 2001 Published by Elsevier Science Ltd. [less ▲]

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See detailProblèmes, situations-problèmes en mathématique : un regard pluraliste.
Schneider, Marguerite ULg

in Mathématique et Pédagogie (2002), 137

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