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See detailLa beauté cachée du lait: enfance et boisson chez Eugène Savitzkaya
Demoulin, Laurent ULg

in Textyles : Revue des Lettres Belges de Langue Française (2003), 23

Parcours dans l'oeuvre d'Eugène Savitzkaya. Examen du thème de l'enfance à travers le motif symbolique récurrent du lait.

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See detailTransfigurative Art: Wilson Harris's The Mask of the Beggar
Maes-Jelinek, Hena ULg

in Moving Worlds : A Journal of Transcultural Writings (2003), 3(2), 12-26

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See detailCalculation of optical absorption spectra of hydrogenated Si clusters: Bethe-Salpeter equation versus time-dependent local-density approximation
Benedict, L. X.; Puzder, A.; Williamson, A. J. et al

in Physical Review. B : Condensed Matter (2003), 68(8), 85310-1-85310-85310-885310-85310-8

We present calculations of the optical absorption spectra of clusters SiH 4, Si 10H 16, Si 17H 36, Si 29H 24, and Si 35H 36, as determined from two different methods: the Bethe-Salpeter equation (BSE ... [more ▼]

We present calculations of the optical absorption spectra of clusters SiH 4, Si 10H 16, Si 17H 36, Si 29H 24, and Si 35H 36, as determined from two different methods: the Bethe-Salpeter equation (BSE) with a model dielectric function, and the time-dependent density-functional theory within the adiabatic local-density approximation (TDLDA). Single-particle states are obtained from local-density approximation (LDA) calculations and, for the BSE calculation, a quasiparticle gap correction is provided by quantum Monte Carlo calculations. We find that the exchange-correlation kernel of the TDLDA has almost no effect on the calculated spectra, while the corresponding attractive part of the electron-hole interaction of the BSE produces enhanced absorptive features at low energies. For the smallest cluster SiH 4, the two methods produce markedly different results, with the TDLDA spectra appearing closer to the experimental result. The gross features of the TDLDA and BSE spectra for larger clusters are however similar, due to the strong repulsive Coulomb kernel present in both treatments [less ▲]

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See detailA review of the major causes of digestive disorders in the European rabbit
Marlier, Didier ULg; Dewrée, Roxane; Delleur, Valéry et al

in Annales de Médecine Vétérinaire (2003), 147(6, DEC-JAN), 385-392

Digestive diseases frequently occur in rabbitries, inducing high mortality rates and huge economic losses. The major causes of these pathological conditions are described in this review. The current state ... [more ▼]

Digestive diseases frequently occur in rabbitries, inducing high mortality rates and huge economic losses. The major causes of these pathological conditions are described in this review. The current state of knowledge on two diseases of unknown origin, the so called Rabbit Epizootic Enteropathy and Mucoid Enteropathy is also presented. [less ▲]

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See detailNombres et jeux enfantins
Lempereur, Françoise ULg

in Enquêtes du Musée de la Vie Wallonne (2003), XX

Children learn to count at school and also by singing and playing traditional games. This paper goes through the traditional Walloon repertory and shows how it fits the childish rhythmics defined by ... [more ▼]

Children learn to count at school and also by singing and playing traditional games. This paper goes through the traditional Walloon repertory and shows how it fits the childish rhythmics defined by ethnomusicologist Constantin Brailoiu [less ▲]

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See detailTwo-dimensional harmonic balance finite element modelling of electrical machines taking motion into account
Gyselinck, Johan; Dular, Patrick ULg; Vandevelde, Lieven et al

in Compel-the International Journal for Computation and Mathematics in Electrical and Electronic Engineering (2003), 22(4), 1021-1036

An original and easy-to-implement method to take into account movement (motion) in the 2D harmonic balance finite element modelling of electrical machines is presented The global harmonic balance system ... [more ▼]

An original and easy-to-implement method to take into account movement (motion) in the 2D harmonic balance finite element modelling of electrical machines is presented The global harmonic balance system of algebraic equations is derived by applying the Galerkin approach to both the space and time discretisation. The harmonic basis functions, i.e. a cosine and a sine function for each nonzero frequency and a constant function 1 for the DC component, are used for approximating the periodic time variation as well as for weighing the time domain equations in the fundamental period. In practice, this requires some elementary manipulations of the moving band stiffness matrix. Magnetic saturation and electrical circuit coupling are considered in the analysis as well. As an application example, the noload operation of a permanent-magnet machine is considered. The voltage and induction waveforms obtained with the proposed harmonic balance method are shown to converge well to those obtained with time stepping. [less ▲]

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See detailPropriétés des merrains affinés dans une solution d’enzymes naturels et destinés à la tonnellerie
Jourez, Benoît ULg; Charron, Stéphane; Hebert, Jacques ULg

in Annals of Forest Science : a Multidisciplinary and International Journal (2003), 60

Properties of shooks ageing by a treatment in a solution of natural enzymes. A speeding up of the ageing of shooks is possible by a treatment with a solution of natural enzymes. However its repercussion ... [more ▼]

Properties of shooks ageing by a treatment in a solution of natural enzymes. A speeding up of the ageing of shooks is possible by a treatment with a solution of natural enzymes. However its repercussion on physical, mechanical characteristics of wood and on its absorption potential of an hydro-alcoholic solution must be tested. Normalized samples have been extracted from 150 shooks selected on a ring width criteria from three cooperages located on different supplying area in France. The three factors cooperage, ring width class and treatment are used for statistical analysis. The cooperage factor, reflection of the supply area of each of them, affect the young modulus and the modulus of rupture in static bending but not the other characteristics. The improvement of the wood properties is closely linked to the ring width increaseof the samples. The enzymatic treatment has no significant effect on physical and mechanical characteristics of oak wood, except on the hardness and, to a lesser extent, on the absorption potential. Considering the absence of negative effect on characteristics of shooks and the positive contribution of enzymatic treatment on their ageing, this treatment could bring a very interesting economical alternative permitting to avoid long lasting storage of the shooks before assembly. [less ▲]

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See detailHybrid magnetic equivalent circuit - finite element modelling of transformer fed electrical machines
Gyselinck, Johan; Dular, Patrick ULg; Legros, Willy ULg et al

in Compel-the International Journal for Computation and Mathematics in Electrical and Electronic Engineering (2003), 22(3), 643-658

This paper deals with the modelling of transformer supply in the two-dimensional (2D) finite element (FE) simulation of rotating electrical machines. Three different transformer models are compared The ... [more ▼]

This paper deals with the modelling of transformer supply in the two-dimensional (2D) finite element (FE) simulation of rotating electrical machines. Three different transformer models are compared The reference one is based on two 2D FE models, considering a cross-section either parallel or perpendicular to the laminations of the magnetic core. The parameters of the two other transformer models, a magnetic equivalent circuit and an electrical equivalent circuit, can be derived from the reference model Particular attention is paid to some common features of the transformer models, e.g. with regard to the inclusion of iron losses. The three models are used in the 2D FE simulation of the steady-state load operation and the starting from stand-still of an induction motor. [less ▲]

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See detailNullité et réduction, note sous Rb. Gent, 4 février 2002
Biquet, Christine ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2003)

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See detailFacteurs de virulence et propriétés spécifiques des souches invasives d'Escherichia coli : II) Franchissement des muqueuses et propriétés invasives
Mainil, Jacques ULg

in Annales de Médecine Vétérinaire (2003), 147(3, JUN-JUL), 159-171

Escherichia coli bacterial species is subdivided into several strains that are pathogenic for man and animals, on the basis of their specific properties and factors which are responsible for their ... [more ▼]

Escherichia coli bacterial species is subdivided into several strains that are pathogenic for man and animals, on the basis of their specific properties and factors which are responsible for their pathogenic characters. The pathogenic strains are classically subdivided into strains with intestinal tropism (enterotoxigenic, enteropathogenic, entero-haemorrhagic, verotoxigenic and enteroinvasive) and with extraintestinal tropism (uropathogenic and invasive). Invasive strains cause septicaemia and/or bacteraemia with localisations in different internal organs (systemic infections). If specific virulence properties and factors of strains with intestinal tropism are quite well known and described, those of strains with extraintestinal tropism are much less characterised, especially in animals. The purpose of this serie of review articles is to present the current knowledge on specific properties and factors of extraintestinal strains : adhesins and colonisation factors, transmucosal transfer and survival in blood and internal organs, toxicity. The fourth manuscript will deal with the invasive strains themselves, focusing on the necrotoxigenic strains. This second manuscript presents the current knowledge on the transmucosal transfer, resistance to the bactericidal activity of the complement, resistance to phagocytosis and production of colicins, that were, for several years, considered as an important specific property of invasive strains of E coli. [less ▲]

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See detailNitric oxide and cardiac function: ten years after, and continuing.
MASSION, Paul ULg; Feron, O.; Dessy, C. et al

in Circulation Research (2003), 93(5), 388-98

Nitric oxide (NO) is produced from virtually all cell types composing the myocardium and regulates cardiac function through both vascular-dependent and -independent effects. The former include regulation ... [more ▼]

Nitric oxide (NO) is produced from virtually all cell types composing the myocardium and regulates cardiac function through both vascular-dependent and -independent effects. The former include regulation of coronary vessel tone, thrombogenicity, and proliferative and inflammatory properties as well as cellular cross-talk supporting angiogenesis. The latter comprise the direct effects of NO on several aspects of cardiomyocyte contractility, from the fine regulation of excitation-contraction coupling to modulation of (presynaptic and postsynaptic) autonomic signaling and mitochondrial respiration. This multifaceted involvement of NO in cardiac physiology is supported by a tight molecular regulation of the three NO synthases, from cellular spatial confinement to posttranslational allosteric modulation by specific interacting proteins, acting in concert to restrict the influence of NO to a particular intracellular target in a stimulus-specific manner. Loss of this specificity, such as produced on excessive NO delivery from inflammatory cells (or cytokine-stimulated cardiomyocytes themselves), may result in profound cellular disturbances leading to heart failure. Future therapeutic manipulations of cardiac NO synthesis will necessarily draw on additional characterization of the cellular and molecular determinants for the net effect of this versatile radical on the cardiomyocyte biology. [less ▲]

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See detailDépression, anxiété, agressivité, impulsivité et comportement suicidaire
PAQUAY, Catherine ULg; PITCHOT, William ULg; Reggers, Jean et al

in Acta Psychiatrica Belgica (2003), 103

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See detailThe spectrum of the roAp star HD 101065 (Przybylski's star) in the Li I 6708 A spectral region
Shavrina, A V; Polosukhina, N S; Pavlenko, Ya V et al

in Astronomy and Astrophysics (2003), 409

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See detailMycoplasma bovis dans le complexe respiratoire bovin et propriétés de cyto-adhésion in vitro
Thomas, Anne; Dizier, Isabelle ULg; Sachse, K. et al

in Annales de Médecine Vétérinaire (2003), 147(4, AUG-SEP), 267-272

Mycoplasmas frequently infect cattle, causing especially respiratory diseases. Mycoplasma bovis is the most important pathogenic species in countries free of bovine contagious pleuropneumonia. This ... [more ▼]

Mycoplasmas frequently infect cattle, causing especially respiratory diseases. Mycoplasma bovis is the most important pathogenic species in countries free of bovine contagious pleuropneumonia. This species was frequently isolated in Belgium from cattle with respiratory disease. Furthermore, associations were often observed with pasteurellas and bovine respiratory syncytial virus. Of these M. bovis isolates, many were resistant to several antimicrobial agents which are used in cattle practice, except to fluoroquinolones. Inasmuch the high frequency of M. bovis isolation and antibiotic resistances, it is very important to understand the pathogenicity of this bacteria in order to optimize prophylactic tools. Therefore, the study of the cytadherence of M. bovis is essential since it represents the first step of the bacterial infection. According to our experimental results, PG45 is not representative of field isolates because of its low adherence rates to various cell lines. This could be explained by the high number of subcultures of this pathogenic strain underwent since its first isolation, which sharply contrasts with other isolates. M. bovis adheres specifically to bovine bronchial epithelial cells in primary culture. Proteins such as variable surface proteins C and F are involved in this step as observed by decreased adherence rates after trypsinization of mycoplasma cells or addition of monoclonal antibodies. [less ▲]

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See detailA recombinant 31.5 kDa keratinase and a crude exo-antigen from Microsporum canis fail to protect against a homologous experimental infection in guinea pigs.
Descamps, Frederic F; Brouta, Frederic; Vermout, Sandy M et al

in Veterinary Dermatology (2003), 14(6), 305-312

A Microsporum canis recombinant 31.5 kDa keratinase and a M. canis crude exo-antigen were tested as vaccines in an experimental infection model in guinea pigs. Animals were vaccinated subcutaneously three ... [more ▼]

A Microsporum canis recombinant 31.5 kDa keratinase and a M. canis crude exo-antigen were tested as vaccines in an experimental infection model in guinea pigs. Animals were vaccinated subcutaneously three times at two-week intervals with either the keratinase, the exo-antigen or the adjuvant alone. Cutaneous challenge was performed blindly. Both humoral and cellular-specific immune responses to M. canis antigens were evaluated every 14 days, while a blind evaluation of clinical lesion development and fungal persistency in skin were monitored weekly. Vaccination induced very high and significant (P < 0.01) antibody responses towards both antigens. High cell-mediated immune responses to both immunogens were also induced by vaccination. After challenge, however, scores reflecting the severity of dermatophytic lesions did not differ significantly between vaccinated and control groups at any time after challenge. These results suggest that, in the guinea pig, the induction of specific immune responses against the M. canis-secreted antigens used in this study are not protective against challenge exposure. [less ▲]

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See detailA stepwise approach for chemical risks assessment at the workplace
Mairiaux, Philippe ULg; Balsat, Alain; Dujardin, Marco et al

Scientific journal (2003)

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See detailNa-23 2D 3QMAS NMR and Si-29, Al-27 MAS NMR investigations of Laponite and synthetic saponites of variable interlayer charge
Delevoye, Laurent; Robert, Jean-Louis; Grandjean, Jean ULg

in Clay Minerals (2003), 38

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See detailNonlinear thin shell finite element for steel and concrete structures subjected to fire: verification and validation
Talamona, Didier; Castagne, Sylvie; Franssen, Jean-Marc ULg

in Journal of Applied Fire Science (2003), 12(1), 65-81

This article presents verification and validation examples for a nonlinear thin shell element developed for structures subjected to fire. The verification benchmarks are: a Z-shaped cantilever, a twisted ... [more ▼]

This article presents verification and validation examples for a nonlinear thin shell element developed for structures subjected to fire. The verification benchmarks are: a Z-shaped cantilever, a twisted cantilever beam, a hemispherical shell, and Lee's frame at room temperature and at elevated temperature. The element shows that it provides results in good agreement with theoretical results and other finite elements. The validation calculations have been performed on an H rolled profile and a concrete slab. The element demonstrates its ability to reproduce local buckling on a H-steel beam under fire conditions and that it predicts accurately the failure of a concrete slab subjected to fire. The theoretical development of this finite element has been published in the Journal of Applied Fire Science, Vol. 11, No. 4, pp. 291-310, "Nonlinear Thin Shell Finite Element for Steel and Concrete Structures Subjected to Fire: Theoretical Development." [less ▲]

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See detailHierarchically mesoporous/macroporous metal oxides templated from polyethylene oxide surfactant assemblies
Blin, J.-L.; Léonard, Alexandre ULg; Yuan, Z.-Y. et al

in Angewandte Chemie International Edition (2003), 42(25), 2872-2875

Wormhole-like mesoporous walls are observed within macroporous metal oxides that were synthesized in one step using nonionic alkyl-PEO surfactants as templates. The uniform macropores have a funnel-like ... [more ▼]

Wormhole-like mesoporous walls are observed within macroporous metal oxides that were synthesized in one step using nonionic alkyl-PEO surfactants as templates. The uniform macropores have a funnel-like shape (tapered towards the center) and are arranged parallel to each other and perpendicular to the tangent of the particle surface (see micrographs). The mesochannels are interconnected with funnel-like macrochannels. [less ▲]

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See detailEstimation of habitat quality based on plant community, and effects of isolation in a network of butterfly habitat patches
Sawchik, J.; Dufrêne, Marc ULg; Lebrun, Philippe

in Acta Oecologica (2003), 24(1), 25-33

Minimum viable site networks are crucial for many threatened species but their design is always a difficult procedure. The present study investigated methods to estimate habitat quality of patches, in an ... [more ▼]

Minimum viable site networks are crucial for many threatened species but their design is always a difficult procedure. The present study investigated methods to estimate habitat quality of patches, in an ecological network for five butterfly species (Brenthis ino, Clossiana selene, Lycaena helle, Lycaena hippothoe, Proclossiana eunomia) inhabiting wet meadows. Abundance predictions were performed on the basis of botanical relevés with a multiple-species approach combining canonical correspondence analysis and multiple regression. Models are defined on a reference site set and are evaluated on a test site set. All the fitted models predicted the abundance of the butterfly species considerably well (from 61 to 86% of the variation). We evaluated the potential consequences of isolation on local populations, by comparing predicted and observed abundance. It was expected that greater differences would be observed when sites were more isolated. On the test set, differences between predicted and observed abundance were largely correlated to site isolation for L. helle and P. eunomia. The most isolated sites had greater chances to be empty, even if they had high-quality habitat. Reciprocally, when the sites were less isolated, the abundance observed was always greater than predicted, seeming to confirm the role of rescue effects. © 2003 Éditions scientifiques et médicales Elsevier SAS. All rights reserved. [less ▲]

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See detailLes onychomycoses--echec et mat?
Arrese Estrada, Jorge ULg; Quatresooz, Pascale ULg; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2003), 58(9), 559-62

According to individuals, onychomycoses or their treatments can be held in check. Some of the "promises" sometimes offered by pharmaceutical companies are not fully kept and hopes of cure may remain wild ... [more ▼]

According to individuals, onychomycoses or their treatments can be held in check. Some of the "promises" sometimes offered by pharmaceutical companies are not fully kept and hopes of cure may remain wild. Some special therapeutic strategies should be employed in case of recalcitrant or recurrent onychomycosis. [less ▲]

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See detailL'herpèsvirus alcélaphin 1, l'agent responsable de la forme africaine du coryza gangreneux
Dewals, Benjamin G ULg; Boudry, Christel ULg; Markine-Goriaynoff, Nicolas ULg et al

in Annales de Médecine Vétérinaire (2003), 147(1, FEB-MAR), 1-15

Malignant catarrhal fever (MCF) is a pathology usually lethal which has been described in a large number of ruminant species. Based on the etiology, two main forms of MCF have been described, i.e., the ... [more ▼]

Malignant catarrhal fever (MCF) is a pathology usually lethal which has been described in a large number of ruminant species. Based on the etiology, two main forms of MCF have been described, i.e., the European and the African forms due to ovine herpesvirus 2 (OvHV-2) and alcelaphine herpesvirus 1 (AlHV-1), respectively. The present review is devoted to the African form of MCF and to its causative agent AlHV-1. AlHV-1 belongs to the Gammaherpesvirinae subfamily of the Herpesviridae family. Wildebeests (Connochaetes spp) carry AlHV-1, which is lethal for a large number of ruminant species, while apparently harmless to its natural host. In hosts susceptible to MCF, the pathology is characterized by fever, extensive lymphadenopathy, ulcerative lesions of the digestive and the upper respiratory tracts mucous membranes and severe keratoconjunctivitis. In the present paper, we will review the data available to date on AlHV-1 and on the African form of MCF with emphasis on the pathogenesis, clinical signs and anatomo-pathological lesions of MCF. Finally, we will discuss the relationship between AlHV-1 and wildebeest as an example of symbiosis between a virus and its natural host. [less ▲]

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See detailOn the use of control surface excitation in flutter testing
Wright, Jan R; Wong, Jerry; Cooper, Jonathan E et al

in Proceedings of the Institution of Mechanical Engineers - Part G - Journal of Aerospace Engineering (2003), 217(6), 317-332

Flutter testing is aimed at demonstrating that the aircraft flight envelope is flutter free. Response measurements from deliberate excitation of the structure are used to identify and track frequency and ... [more ▼]

Flutter testing is aimed at demonstrating that the aircraft flight envelope is flutter free. Response measurements from deliberate excitation of the structure are used to identify and track frequency and damping values against velocity. In this paper, the common approach of using a flight control surface to provide the excitation is examined using a mathematical model of a wing and control surface whose rotation is restrained by a simple actuator. In particular, it is shown that it is essential to use the demand signal to the actuator as a reference signal for data processing. Use of the actuator force (or strain) or control angle (or actuator displacement) as a reference signal is bad practice because these signals contain response information. It may also be dangerous in that the onset of flutter may not be seen in the test results. [less ▲]

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See detailTowards an Understanding of Hafting: the macro- and microscopic evidence
Rots, Veerle ULg

in Antiquity (2003), 77(298), 805-815

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See detailKorean experience with the OSTA risk index for osteoporosis: a validation study.
Park, H. M.; Sedrine, W Ben; Reginster, Jean-Yves ULg et al

in Journal of Clinical Densitometry : The Official Journal of the International Society for Clinical Densitometry (2003), 6(3), 247-50

The Osteoporosis Self-assessment Tool for Asians (OSTA) was developed to help physicians focus their efforts on patients at increased risk, and encourage appropriate use of bone mineral density (BMD ... [more ▼]

The Osteoporosis Self-assessment Tool for Asians (OSTA) was developed to help physicians focus their efforts on patients at increased risk, and encourage appropriate use of bone mineral density (BMD) measurements. Previously, OSTA performed well in a sample of women from eight countries in Asia, and in a validation group of Japanese women. In this study, we evaluate the performance of OSTA using a sample of 1101 postmenopausal women from a clinic in Korea who had femoral neck BMD measurements by dual-energy X-ray absorptiometry (DXA). The OSTA had a high sensitivity (87%), and good specificity (67%) for identifying osteoporosis (BMD T-scores <or= -2.5); the corresponding values were 80% and 72% for identifying T-scores <or= -2.0. The prevalence of osteoporosis ranged from 2% among women classified as low risk (OSTA > -1) to 64% among those classified as high risk (OSTA < -4); these results were almost identical to those reported earlier for a sample of women from eight Asian countries. We conclude that the OSTA risk tool performed well in this sample of postmenopausal Korean women, similar to previous results in other Asian women. The OSTA tool is free and very easy to use; risk can be tabulated by age and weight, so that calculations are not necessary. Using OSTA could encourage patients and clinicians to actively assess osteoporosis, and measure BMD when appropriate, before fractures occur. [less ▲]

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See detailVariations at different spatial scales of Posidonia oceanica (L.) Delile beds; effects on the physico-chemical parameters of the sediment
Gobert, Sylvie ULg; Kyramarios, Michael; Lepoint, Gilles ULg et al

in Oceanologica Acta (2003), 26(2), 199-207

The biometric parameters (shoot density, length and width of leaves, leaf and epiphyte biomasses, leaf surface) of the P. oceanica meadow present a significant spatial variability at the mesoscale level ... [more ▼]

The biometric parameters (shoot density, length and width of leaves, leaf and epiphyte biomasses, leaf surface) of the P. oceanica meadow present a significant spatial variability at the mesoscale level (100 m2). All the parameters studied, excepting the number of leaves, decrease according to the depth. The horizontal spatial variations (centrifuge and centripetal distributions) reach a maximum in the shallower areas. The analysis of the microstructures (m2) of the meadow has not allowed a relationship to be established between the spatial variations of the biometric parameters and the environmental factors in the sediment (pH, water and organic matter content, red-ox potential, nutrient content). The heterogeneity of the meadow in the Revellata Bay quite probably results from the internal shoot and rhyzome growth dynamics. <br />On the other hand, it appears that the presence of the prairie modifies the physical-chemical characteristics of the sediment. In fact, the sandy patches present different physical-chemical characteristics: lower organic matter, different granulometric and much higher interstitial water nutrient levels, as well as a higher pH and oxydo-reduction potential. [less ▲]

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See detailThe lichen genus Caprettia Bat. & H. Maia
Sérusiaux, Emmanuël ULg; Lücking, Robert

in Bibliotheca Lichenologica (2003), 86

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See detail"Sum Petri Aegidii" : kanttekeningen bij een recent opgedoken boek uit de bibliotheek van Pieter Gillis (1486-1533)
Adam, Renaud ULg

in De Gulden Passer = Le compas d'or (2003), 81

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See detailIntroduction
Jacquemain, Marc ULg; Verjans, Pierre ULg

in Fédéralisme - Régionalisme (2003), 2002-2003(n° spécial « Mobilité et identités dans l’Eurégio Meuse-Rhin »), 3-11

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See detailApplication of the fast multipole method to the 2D finite element-boundary element analysis of electromechanical devices
V Sabariego, Ruth ULg; Gyselinck, J.; Geuzaine, Christophe ULg et al

in COMPEL (2003), 22(3), 659-673

The present paper deals with the fast multipole acceleration of the 2D finite element-boundary element modelling of electromechanical devices. It is shown that the fast multipole method, usually applied ... [more ▼]

The present paper deals with the fast multipole acceleration of the 2D finite element-boundary element modelling of electromechanical devices. It is shown that the fast multipole method, usually applied to large 3D problems, can also lead to a reduction in computational time when dealing with relatively small 2D problems, provided that an adaptive truncation scheme for the expansion of the 2D Laplace Green function is used. As an application example, the 2D hybrid modelling of a linear actuator is studied, taking into account saturation, the voltage supply and the mechanical equation. The computational cost without and with fast multipole acceleration is discussed for both the Linear and nonlinear case. [less ▲]

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See detailLes marques de provenance des incunables conservés à la Bibliothèque royale de Belgique : essai de synthèse
Adam, Renaud ULg

in Archives et Bibliothèques de Belgique = Archief en Bibliotheekwezen in Belgie (2003), 75

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See detailLarge phosphorus hyperfine coupling as a sensitive tool for studying molecular dynamics : ESR and Molecular Mechanics studies of ring interconversion in cis-2,5-diphosphoryl-2,5-dimethyl-pyrrolidinoxyl radical
Rockenbauer, Antal; Gaudel-Siri, Anouk; Siri, Didier et al

in Journal of Physical Chemistry A (2003), 107(19), 3851-3857

ESR spectra of cis- and trans-â-diphosphorylated pyrrolidine-N-oxyl radicals, c-1 and t-1, were studied in liquid and frozen solution. The expected 1:2:1 triplet (aP (2)) of the 1:1:1 triplet (aN) was ... [more ▼]

ESR spectra of cis- and trans-â-diphosphorylated pyrrolidine-N-oxyl radicals, c-1 and t-1, were studied in liquid and frozen solution. The expected 1:2:1 triplet (aP (2)) of the 1:1:1 triplet (aN) was observed for t-1; however, for c-1, the inner lines of the 1:2:1 triplet showed a dramatic broadening characteristic of chemical exchange between two equivalent conformations. Owing to the large difference in the hyperfine splitting constants (hfsc) of the exchanging phosphorus (¢aP 21 G), the coalescence temperature was unusually high (193 K, in n-pentane), and the potential barrier for ring interconversion (10.5 kJ mol-1) was easily obtained from the temperature dependence of the exchange rate. This value was in very good agreement with the value obtained for an empirical pseudorotational potential (11 kJ mol-1) that was adjusted to fit the temperature dependence of the phosphorus hfsc. For c-1, molecular mechanics calculations gave similar characteristics for the pseudorotational potential and indicated the existence of two identical minima with distorted geometries lying between 3T4 and 3E or 4T3 and E3. For t-1, only the 3T4 conformer was found to be significantly populated. Frozen solution spectra showed that the phosphorus hfsc anisotropy is higher when the C-P bond is pseudoaxial; this result can be explained by a geometry-dependent delocalization of the unpaired electron into the phosphorus 3p orbitals. [less ▲]

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See detailRENO, a European Postmarket Surveillance Registry, confirms effectiveness of coronary brachytheraypy in routine clinical practice.
Coen, V; Serruys, P; Sauerwein, W et al

in International Journal of Radiation, Oncology, Biology, Physics (2003), 55(4), 1019-1026

Purpose: To assess, by a European registry trial, the clinical event rate in patients with discrete stenotic lesions of coronary arteries (de novo or restenotic) in single or multiple vessels (native or ... [more ▼]

Purpose: To assess, by a European registry trial, the clinical event rate in patients with discrete stenotic lesions of coronary arteries (de novo or restenotic) in single or multiple vessels (native or bypass grafts) treated with -radiation. Methods and Materials: Between April 1999 and September 2000, 1098 consecutive patients treated in 46 centers in Europe and the Middle East with the Novoste Beta-Cath System were included in Registry Novoste (RENO). Results: Six-month follow-up data were obtained for 1085 patients. Of 1174 target lesions, 94.1% were located in native vessels and 5.9% in a bypass graft; 17.7% were de novo lesions, 4.1% were restenotic, and 77.7% were in-stent restenotic lesions. Intravascular brachytherapy was technically successful in 95.9% of lesions. Multisegmental irradiation, using a manual pullback stepping maneuver to treat longer lesions, was used in 16.3% of the procedures. The in-hospital rate of major adverse cardiac events was 1.8%. At 6 months, the rate was 18.7%. Angiographic follow-up was available for 70.4% of the patients. Nonocclusive restenosis was seen in 18.8% and total occlusion in 5.7% of patients. A combined end point for late (30–180 days) definitive or suspected target vessel closure was reached in 5.4%, but with only 2% of clinical events. Multivariate analysis was performed for major adverse cardiac events and late thrombosis. Conclusion: Data obtained from the multicenter RENO registry study, derived from a large cohort of unselected consecutive patients, suggest that the good results of recent randomized controlled clinical trials can be replicated in routine clinical practice. © 2003 Elsevier Science Inc. [less ▲]

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See detailBook Review: Theories of Endogenous Regional Growth: Lessons for Regional Policies,
Artige, Lionel ULg; Nicolini, Rosella

in Journal of Regional Science (2003), 43(2), 403-406

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See detailInteraction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression.
Twizere, Jean-Claude ULg; Kruys, Veronique; Lefebvre, Laurent et al

in Journal of the National Cancer Institute (2003), 95(24), 1846-59

BACKGROUND: The Tax oncoproteins are transcriptional regulators of viral expression involved in pathogenesis induced by complex leukemogenic retroviruses (or delta-retroviruses, i.e., primate T-cell ... [more ▼]

BACKGROUND: The Tax oncoproteins are transcriptional regulators of viral expression involved in pathogenesis induced by complex leukemogenic retroviruses (or delta-retroviruses, i.e., primate T-cell leukemia viruses and bovine leukemia virus). To better understand the molecular pathways leading to cell transformation, we aimed to identify cellular proteins interacting with Tax. METHODS: We used a yeast two-hybrid system to identify interacting cellular proteins. Interactions between Tax and candidate interacting cellular proteins were confirmed by glutathione S-transferase (GST) pulldown assays, co-immunoprecipitation, and confocal microscopy. Functional interactions between Tax and one interacting protein, tristetraprolin (TTP), were assessed by analyzing the expression of tumor necrosis factor-alpha (TNF-alpha), which is regulated by TTP, in mammalian cells (HeLa, D17, HEK 293, and RAW 264.7) transiently transfected with combinations of intact and mutant Tax and TTP. RESULTS: We obtained seven interacting cellular proteins, of which one, TTP, was further characterized. Tax and TTP were found to interact specifically through their respective carboxyl-terminal domains. The proteins colocalized in the cytoplasm in a region surrounding the nucleus of HeLa cells. Furthermore, coexpression of Tax was associated with nuclear accumulation of TTP. TTP is an immediate-early protein that inhibits expression of TNF-alpha at the post-transcriptional level. Expression of Tax reverted this inhibition, both in transient transfection experiments and in stably transfected macrophage cell lines. CONCLUSION: Tax, through its interactions with the TTP repressor, indirectly increases TNF-alpha expression. This observation is of importance for the cell transformation process induced by leukemogenic retroviruses, because TNF-alpha overexpression plays a central role in pathogenesis. [less ▲]

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See detailL’herpèsvirus bovin 4
Markine-Goriaynoff, N.; Minner, F.; De Fays, K. et al

in Annales de Médecine Vétérinaire (2003), 147(4), 215-247

Bovine herpesvirus 4 (BoHV-4) belongs to the Herpesviridae family, Gammaherpesvirinae subfamily, Rhadinovirus genus like human herpesvirus 8 (HHV-8), the causative agent of Kaposi's sarcoma. BoHV-4 has a ... [more ▼]

Bovine herpesvirus 4 (BoHV-4) belongs to the Herpesviridae family, Gammaherpesvirinae subfamily, Rhadinovirus genus like human herpesvirus 8 (HHV-8), the causative agent of Kaposi's sarcoma. BoHV-4 has a worldwide distribution in the cattle population. It has been isolated from cattle showing various clinical signs as well as from healthy cattle. The interest of the scientific community for BoHV-4 is explained by two reasons. Firstly, BoHV-4 represents an homologous virus/host species model to study the biology of gammaherpesviruses. Secondly, the use of BoHV-4 as a recombinant vector for expression both in vitro and in vivo has been proposed. For these reasons, a considerable amount of data has been collected on this virus. In the present paper, the authors will present a general overview of the literature published on this virus addressing clinical, epidemiological and fundamental aspects of BoHV-4. Finally, in the light of their recent phylogenetic data, the authors will discuss the origin and the host species of BoHV-4 leading to the conclusion that this virus should be considered as a virus of the African buffalo rather than cattle. [less ▲]

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See detailLe Musée en Piconrue de Bastogne
Donneau, Olivier ULg

in Invitation au musée : Courrier du patrimoine culturel de la Communauté française (2003), 4

Courte présentation des activités du Musée en Piconrue de Bastogne.

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See detailReal-time reconstruction of the vertical electron density distribution from GPS TEC measurements
Stankov, Stanimir; Warnant, René ULg; Jodogne, Jean-Claude

in Acta Geodaetica et Geophysica Hungarica (2003), 38(4), 377-388

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See detailEpidemiology, clinical presentation and diagnostic strategy of gastro-esophageal reflux
Louis, Edouard ULg

in Acta Endoscopica (2003), 33

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See detailMagnetic fabrics in the Holum granite (Vest-Agder, southernmost Norway): implications for the late evolution of the Sveconorwegian (Grenvillian) orogen of SW Scandinavia
Bolle, Olivier ULg; Diot, Hervé; Trindade, Ricardo I.F.

in Precambrian Research (2003), 121(3-4), 221-249

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See detail“Beauté, mon beau souci”. Propos sur une biographie de l’éditeur belge Edmond Deman
Durand, Pascal ULg

in Epilogue, Bulletin canadien pour l’histoire du livre et l’histoire des bibliothèques et des archives (2003), 13

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See detailLa Belgique francophone face au référendum sarrois de 1955
Lanneau, Catherine ULg

in Revue d'Allemagne et des Pays de Langue Allemande (2003), 35(4), 525-545

Since 1945, French-speaking Belgians were looking at the « Saar problem », stumbling block of Europe’s build-up, with a mixture of awe and hope. In 1955, as the inhabitants were asked to vote on a ... [more ▼]

Since 1945, French-speaking Belgians were looking at the « Saar problem », stumbling block of Europe’s build-up, with a mixture of awe and hope. In 1955, as the inhabitants were asked to vote on a peculiar status of “Europeanised” autonomous territory (within the WEU but keeping economical union with France), the coming plebiscite was seen as a good bid on Europe’s future. At first, Belgian public opinion was under the influence of optimistic statements made by official French and autonomist propaganda. After the failure of the plebiscite, Belgian journalists and diplomats tried to find some simple and often rather bombastic explanations: intern and extern weakness of France seen as over-cautious or tinted with europhobia, lack of appeal of the European idea, attractiveness of the German economical bloom, Nazi nostalgia or even perennial nationalism of the German man. Then, Saarland, having refused to be an oddity in a nation-based Europe, fell from public interest into oblivion... [less ▲]

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See detailTwo new atrypid brachiopod species from the late Frasnian of Belgium
Mottequin, Bernard ULg

in Bulletin de l'Institut Royal des Sciences Naturelles de Belgique. Sciences de la Terre (2003), 73

Two new species of atrypid brachiopods from the late Frasnian Lambermont and Barvaux formations of Belgium are described (south-east border of the Dinant and the Vesdre Nappe), Iowatrypa ultima n. sp. and ... [more ▼]

Two new species of atrypid brachiopods from the late Frasnian Lambermont and Barvaux formations of Belgium are described (south-east border of the Dinant and the Vesdre Nappe), Iowatrypa ultima n. sp. and Spinatrypa (Spinatrypa) lambermontensis n. sp. These species rank among the last representatives of the order Atrypida in the Ardennes (Upper Palmatolepis rhenana Zone). [less ▲]

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See detailMeasure Noun constructions : an instance of semantically-driven grammaticalization
Brems, Lieselotte ULg

in International Journal of Corpus Linguistics (2003), 8(2), 283-312

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See detailLe point sur la place du Robinier en Hongrie
Fourbisseur, Anne; Charron, Stéphane; Jourez, Benoît ULg et al

in Forêt Wallonne (2003), (67), 26-30

Le robinier est une des deux essences les plus importantes en Hongrie1-2. Ce pays est mondialement reconnu comme chef de file pour la gestion de la ressource en robinier, depuis la <br />recherche en ... [more ▼]

Le robinier est une des deux essences les plus importantes en Hongrie1-2. Ce pays est mondialement reconnu comme chef de file pour la gestion de la ressource en robinier, depuis la <br />recherche en amélioration génétique jusqu’à la valorisation industrielle de son bois. Cet article se propose de faire la synthèse des connaissances acquises en Hongrie sur le développement de la <br />filière bois du robinier. L’objectif est de partager l’expérience hongroise avec ceux qui intéressent à cette essence à haut potentiel. Un bref historique de l’implantation du robinier dans ce pays sera exposé et suivi de l’état actuel de la ressource et d’une présentation succincte <br />des caractéristiques climatiques et édaphiques propres à la Hongrie. La sylviculture propre au robinier sera détaillée et les principales utilisations des produits ligneux seront décrites. Cette ynthèse s’achèvera avec la présentation de la collaboration sur le thème du robinier conclue <br />entre la Région wallonne, la Communauté française de Belgique et la République de Hongrie. [less ▲]

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See detailImpact of medical specialist' locus of control on communication skills in oncological interviews
Libert, Y.; Janne, P.; Razavi, D. et al

in British Journal of Cancer (2003), 88

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See detailExamen de jurisprudence (1995-2001). Contrat de travail
Kefer, Fabienne ULg; Clesse, Jacques ULg

in Revue Critique de Jurisprudence Belge (2003)

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See detailDifference in risk factors for postoperative nausea and vomiting.
Stadler, Michaela; Bardiau, Françoise ULg; Seidel, Laurence ULg et al

in Anesthesiology (2003), 98(1), 46-52

BACKGROUND: It is commonly stated that risk factors for postoperative nausea are the same as for vomiting. The authors designed a prospective study to identify and differentiate the risk factors for ... [more ▼]

BACKGROUND: It is commonly stated that risk factors for postoperative nausea are the same as for vomiting. The authors designed a prospective study to identify and differentiate the risk factors for postoperative nausea and vomiting in various surgical populations in a clinical audit setting. METHODS: The study included 671 consecutive surgical inpatients, aged 15 yr or more, undergoing various procedures. The study focused on postoperative nausea visual analog scale scores every 4 h and vomiting episodes within 72 h. Both vomiting and retching were considered as emetic events. Patient-, anesthesia-, and surgery-related variables that were considered to have a possible effect on the proportion of patients experiencing postoperative nausea and/or vomiting were examined. The bivariate Dale model for binary correlated outcomes was used to identify selectively the potential risk factors of postoperative nausea and vomiting. RESULTS: Among the 671 patients in the study, 126 (19%) reported one or more episodes of nausea, and 66 patients (10%) suffered one or more emetic episodes during the studied period. There was a highly significant association between the two outcomes. Some risk factors were predictive of both nausea and vomiting (female gender, nonsmoking status, and general anesthesia). History of migraine and type of surgery were mainly responsible for nausea but not for vomiting. The predictive effect of risk factors was controlled for postoperative pain and analgesic drugs. CONCLUSION: This study shows that differences exist in risk factors of postoperative nausea and vomiting. These could be explained by differences in the physiopathology of the two symptoms. [less ▲]

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See detailLe cas clinique du mois. La maladie de still de l'adulte: une cause rare d'hepatite aigue febrile
Michels, V.; Delwaide, Jean ULg; Vermeulen, P. et al

in Revue Médicale de Liège (2003), 58(12), 729-733

A 63-year-old woman was hospitalized for the third time in one year for asthenia, fever and chills, jaundice, cytolysis and cholestasis. An adult onset Still's disease was diagnosed. Hepatic ... [more ▼]

A 63-year-old woman was hospitalized for the third time in one year for asthenia, fever and chills, jaundice, cytolysis and cholestasis. An adult onset Still's disease was diagnosed. Hepatic manifestations, diagnostic criteria and efficient therapy of AOSD will be reviewed. [less ▲]

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See detailJansénisme et monachisme féminin aux pays de Liège et de Luxembourg
Henneau, Marie-Elisabeth ULg

in Chroniques de Port-Royal (2003), 52

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See detailFestina lente: evidences for fast and slow learning processes and a role for sleep in human motor skill learning.
Maquet, Pierre ULg; Laureys, Steven ULg; Perrin, Fabien et al

in Learning & Memory (Cold Spring Harbor, N.Y.) (2003), 10(4), 237-9

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See detailShortened irradiation scheme, continuous infusion of 5-fluorouracil and fractionation of mitomycin C in locally advanced anal carcinomas. Results of a phase II study of the European Organization for Research and Treatment of Cancer. Radiotherapy and Gastrointestinal Cooperative Groups
Bosset, J. F.; Roelofsen, F.; Morgan, D. A. L. et al

in European Journal of Cancer (2003), 39

Abstract The European Organization for Research and Treatment of Cancer (EORTC) 22861 randomised trial established that combined radiochemotherapy is the standard treatment for locally advanced anal ... [more ▼]

Abstract The European Organization for Research and Treatment of Cancer (EORTC) 22861 randomised trial established that combined radiochemotherapy is the standard treatment for locally advanced anal cancer. This EORTC phase II study (#22953) tests the feasibility of reducing the gap between sequences to 2 weeks, to deliver Mitomycin C (MMC) in each radiotherapy sequence and 5-FU continuously during the treatment. The first sequence consisted of 36 Gy over 4 weeks. 5-FU 200 mg/m2/days 1–26, MMC 10 mg/m2/day 1 gap 16 days. Then a second sequence of 23.4 Gy over 17 days, 5-FU 200 mg/m2/days 1–17 and, MMC 10 mg/m2/day 1 was given. 43 patients with a World Health Organization (WHO) status of 0 (n=27) or 1 (n=16) and with T2-T4, N0-3 tumours were included. Compliance with the planned treatment, doses and duration was 93%. The complete response rate was 90.7%. Grade 3 toxicities of 28, 12 and 2% were observed for skin, diarrhoea and haematological toxicities, respectively. The 3-year estimated rates for trials 22861 and 22953 are: 68 and 88% for local control; 72 and 81% for colostomy-free interval, 62 and 84% for severe late toxicity-free interval, and 70 and 81% for survival, respectively. The 22953 scheme is feasible and the results are promising. This is now considered as the new standard scheme by the EORTC. [less ▲]

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See detailProlactin Suppresses Glucocorticoid-Induced Thymocyte Apoptosis in Vivo
Krishnan, Nithya; Thellin, Olivier ULg; Buckley, Donna J. et al

in Endocrinology (2003), 144(5), 2102-2110

The hypothesis that prolactin (PRL) functions as an immunomodulator was based on studies showing lymphocyte PRL receptors, and its effects on growth, differentiation, and apoptosis in lymphoid cells ... [more ▼]

The hypothesis that prolactin (PRL) functions as an immunomodulator was based on studies showing lymphocyte PRL receptors, and its effects on growth, differentiation, and apoptosis in lymphoid cells. However, studies of PRL (PRL-/-) and PRL receptor knockout mice indicated that PRL was not required for immune system development or function under basal conditions. Because PRL maintains survival in glucocorticoid (GC)-treated Nb2-T lymphocytes in vitro, and PRL and GCs are elevated during stress, we investigated whether PRL protected T cells in vivo from GC-induced apoptosis. Adrenalectomized mice [PRL -/-, undetectable PRL; pituitary grafted PRL-/- (PRL-/-Graft), elevated PRL; and PRL+/-, normal PRL] were treated with dexamethasone (DEX) or PBS. Thymocytes and splenocytes were isolated and annexin V labeling of phosphatidylserine, DNA fragmentation, and caspase-3 activation were assessed as indices of apoptosis. Total thymocytes and CD4+ and CD8+ T cells obtained from DEX-treated PRL-/- mice exhibited significantly increased annexin V binding. In contrast, binding was not altered by DEX in PRL-/-Graft thymocytes. In addition, DEX induced classic DNA fragmentation in PRL-/- thymocytes. Elevated serum PRL reduced this effect. Thymocytes from DEX-treated PRL-/- mice exhibited increased caspase-3 activation, which was inhibited in cells from PRL-/-Graft mice. Finally, elevated expression of X-linked inhibitor of apoptosis, XIAP, was observed in thymi from DEX-treated PRL -/-Graft mice. This is the first demonstration that elevated PRL antagonizes apoptosis in thymocytes exposed to GCs in vivo. These observations suggest that, under conditions of increased GCs, such as during stress, elevated PRL functions physiologically to maintain survival and function of T-lymphocytes. [less ▲]

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See detailIncidence and survival rate of women with cervical cancer in the Greater Amsterdam area.
BULK, Saskia ULg; Visser, O.; Rozendaal, L. et al

in British journal of cancer (2003), 89(5), 834-9

To evaluate the effect of population-based cervical cancer screening on the occurrence of cervical cancer in The Netherlands, we investigated the incidence and survival of cervical cancer registered by a ... [more ▼]

To evaluate the effect of population-based cervical cancer screening on the occurrence of cervical cancer in The Netherlands, we investigated the incidence and survival of cervical cancer registered by a cancer registry in the Greater Amsterdam area. The incidence rate of squamous cell carcinoma decreased significantly from 9.2/100,000 women in 1988 to 5.9/100,000 in 2000 (P<0.001). The incidence rate of adenocarcinomas remained stable. After adjustment for age, stage and lymph node involvement, the relative risk of death was 1.6 times higher for patients with adenocarcinomas than for patients with squamous cell carcinoma (95% CI 1.2-2.1). The decreased survival was related to histological type, as the effect remained significant after correction for confounding factors. Over time, the prognosis of women with squamous cell carcinoma improved significantly. No significant change was observed for women diagnosed with adenocarcinoma. These results suggest that the screening programme in The Netherlands as executed in the Greater Amsterdam area is associated with a decreased incidence and increased survival of patients with squamous cell carcinoma, but fails to detect (pre)malignant lesions of adenocarcinoma. Since more than 92% of adenocarcinomas and its precursors contain high-risk HPV, adding HPV testing to cytologic screening might improve the present screening programme in detecting adenocarcinoma and its precursor lesions. [less ▲]

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See detailConditions for elasto-plastic strain localization in unsaturated soils
Charlier, Robert ULg; Baltov, A.; Datcheva, Maria et al

in Journal of Theoretical and Applied Mechanics (2003), 33(3), 101-118

The necessary and sufficient conditions for elasto-plastic strain localization initiation in unsaturated soli massifs are proposed. Unsaturated behaviour is described unsing net stress and suction as ... [more ▼]

The necessary and sufficient conditions for elasto-plastic strain localization initiation in unsaturated soli massifs are proposed. Unsaturated behaviour is described unsing net stress and suction as independent stress variables and modifying the basic constitutive surface parameters and hardening rules to consider the role of suction. The process is accepted to be static isothermal. The conception that the localization band initiates due to loss of stability of deformation process is used. In that case, the rates of process measures bifurcate. A special example is given to illustrate the application of the obtained conditions. [less ▲]

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See detailUne approche neuropsychologique des relations entre mémoire épisodique et mémoire sémantique
Bastin, Christine ULg; Van der Linden, Martial ULg

in Revue de Neuropsychologie (2003), 13(1), 3-69

Cognitive models of the organization of memory propose different conceptions of the relationships between episodic and semantic memory. In the present review, we consider two influential models. According ... [more ▼]

Cognitive models of the organization of memory propose different conceptions of the relationships between episodic and semantic memory. In the present review, we consider two influential models. According to one model (Tulving, 1995), episodic and semantic memory are two functionally and anatomically distinct systems. Their relationships are referred to as “embeddedness”, that is, information must be encoded in semantic memory in order to achieve episodic memory. Another model (Squire & Zola, 1998) describes episodic and semantic memory as two subsystems of declarative memory. Both depend on the same brain region and should be impaired in amnesic patients. Furthermore, information is usually first encoded in episodic memory, before being transferred to semantic memory. In this review, we describe the neuropsychological data that support each model, as well as studies that contradict these models. Three sets of evidence are described. First, we consider recognition memory in amnesic patients. Recognition memory processes, recollection and familiarity, have been related to episodic and semantic memory, respectively (Tulving, 1995). Contradictory findings exist concerning the relative preservation of familiarity-based recognition in certain types of amnesic patients. Then we describe studies that have examined whether amnesic patients can learn new semantic information or not. Finally, episodic learning in semantic dementia is considered. [less ▲]

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See detailGuidelines for clinical studies assessing the efficacy of drugs for the management of acute low back pain
Devogelaer, J. P.; Dreiser, R. L.; Abadie, Eric ULg et al

in Clinical and Experimental Rheumatology (2003), 21(6, NOV-DEC), 691-694

In this paper we propose guidelines for clinical trials aimed at assessing the efficacy of drugs for acute non-specific low back pain (LBP) with or without radicular pain, preliminary to their approval ... [more ▼]

In this paper we propose guidelines for clinical trials aimed at assessing the efficacy of drugs for acute non-specific low back pain (LBP) with or without radicular pain, preliminary to their approval and registration. To this end, consensus statements were obtained from a group of experts in the fields of rheumatology, clinical medicine, public health and epidemiology. EBM resources were systematically used as references. [less ▲]

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See detailGene flow among wild Phaseolus lunatus L. populations in the Central Valley of Costa Rica
Ouedraogo, M.; Maquet, A.; Baudoin, Jean-Pierre ULg

in Annual Report Bean Improvement Cooperative (2003), 46

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See detailAmélioration de la détection d’une maladie émergente : exemple de l’ encépahlopathie spongiforme bovine
Saegerman, Claude ULg; Berkvens, D.; Speybroeck, N. et al

in Epidémiologie et Santé Animale (2003), 44

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See detailEvaluation of false transrectal ultrasonographic pregnancy diagnoses in sheep by measuring the plasma level of pregnancy-associated glycoproteins
Karen, A.; Beckers, Jean-François ULg; Sulon, Joseph ULg et al

in Reproduction Nutrition Development (2003), 43(6, NOV-DEC), 577-586

The present study was undertaken to investigate to what extent pregnancy diagnoses made by transrectal ultrasonography could be confirmed by measurements of plasma concentration of ovine pregnancy ... [more ▼]

The present study was undertaken to investigate to what extent pregnancy diagnoses made by transrectal ultrasonography could be confirmed by measurements of plasma concentration of ovine pregnancy-associated glycoproteins (ovPAG). A total of 424 Awassi x Merino ewes were synchronized for estrus and examined by transrectal ultrasonography. In Experiment 1, the ewes (n = 156) were repeatedly scanned in a standing position on d 29, 36 and 50 of gestation. Similarly, the ewes (n = 268) in Experiment 2 were scanned on d 24, 29 and 34 of gestation, but these ewes were fasted for 12 h prior to the examination and the abdominal wall of each animal was lifted up by the hands of the assistant during the scanning. Blood samples were withdrawn after each transrectal ultrasonographic examination in both experiments. Ovine PAG concentrations were measured in plasma by a heterologous radioimmunoassay and the cut-off value for pregnancy was greater than or equal to 1 ng.mL(-1). Based on the lambing performance, in Experiment 1, altogether 47 false negative and 38 false positive diagnoses were made by transrectal ultrasonography in 24 and 33 ewes, respectively between d 29 and 50 of gestation. In Experiment 2, altogether 8 false negative and 13 false positive diagnoses both were made in 7 ewes between d 24 and 34 of gestation. In both experiments, all ewes with false negative diagnoses had ovPAG concentrations higher than the threshold level for pregnancy diagnosis and all ewes with false positive diagnoses had ovPAG concentrations lower than the threshold of pregnancy. Furthermore, by the PAG-RIA test all lambed or aborted ewes (n = 63) were correctly diagnosed as pregnant and with three exceptions, all non-lambed ewes (n = 361) were correctly diagnosed as non-pregnant during the examined periods of both experiments. [less ▲]

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See detailMemory processing during human sleep as assessed by functional neuroimaging.
Maquet, Pierre ULg; Peigneux, Philippe ULg; Laureys, Steven ULg et al

in Revue Neurologique (2003), 159(11 Suppl), 627-9

Sleep is believed to participate in memory consolidation, possibly through off-line processing of recent memory traces. In this paper, we summarize functional neuroimaging data testing this hypothesis ... [more ▼]

Sleep is believed to participate in memory consolidation, possibly through off-line processing of recent memory traces. In this paper, we summarize functional neuroimaging data testing this hypothesis. First, sleep deprivation disrupts the processing of recent memory traces and hampers the changes in functional segregation and connectivity which underpin the gain in performance usually observed in subjects allowed to sleep on the first post-training night. Second, experience-dependent changes in regional brain activity occur during post-training sleep. These changes are shown to be related to the processing of high-level material and to be modulated by the amount of learning achieved during the training session. These changes do not involve isolated brain areas but entire macroscopic cerebral networks. These data suggest a role for sleep in the processing of recent memory traces. [less ▲]

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See detailUse of the impulse oscillometry system for testing pulmonary function during methacholine bronchoprovocation in horses.
Van Erck, Emmanuelle ULg; Votion, Dominique ULg; Kirschvink, Nathalie et al

in American Journal of Veterinary Research (2003), 64(11), 1414-1420

OBJECTIVE: To compare sensitivity of the impulse oscillometry system (IOS) with that of the conventional reference technique (CRT; ie, esophageal balloon method) for pulmonary function testing in horses ... [more ▼]

OBJECTIVE: To compare sensitivity of the impulse oscillometry system (IOS) with that of the conventional reference technique (CRT; ie, esophageal balloon method) for pulmonary function testing in horses. ANIMALS: 10 horses (4 healthy; 6 with recurrent airway obstruction [heaves] in remission). PROCEDURE: Healthy horses (group-A horses) and heaves-affected horses (group-B horses) were housed in a controlled environment. At each step of a methacholine bronchoprovocation test, threshold concentration (TC(2SD); results in a 2-fold increase in SD of a value) and sensitivity index (SI) were determined for respiratory tract system resistance (R(rs)) and respiratory tract system reactance (X(rs)) at 5 to 20 Hz by use of IOS and for total pulmonary resistance (RL) and dynamic lung compliance (C(dyn)), by use of CRT. RESULTS: Bronchoconstriction resulted in an increase in R(rs) at 5 Hz (R(5Hz)) and a decrease in X(rs) at all frequencies. Most sensitive parameters were X(rs) at 5 Hz (X(5Hz)), R(5Hz), and R(5Hz):R(10Hz) ratio; RL and the provocation concentration of methacholine resulting in a 35% decrease in dynamic compliance (PC(35)C(dyn)) were significantly less sensitive than these IOS parameters. The TC(2SD) for X(rs) at 5 and 10 Hz was significantly lower in group-B horses, compared with group-A horses. The lowest TC(2SD) was obtained for X(5Hz) in group-B horses and R(5Hz) in group-A horses. CONCLUSIONS AND CLINICAL RELEVANCE: In contrast to CRT parameters, IOS parameters were significantly more sensitive for testing pulmonary function.The IOS provides a practical and noninvasive pulmonary function test that may be useful in assessing subclinical changes in horses. [less ▲]

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See detailNucleation phenomenon in silica xerogels and Pd/SiO2, Ag/SiO2, Cu/SiO2 cogelled catalysts
Alié, Christelle ULg; Lambert, Stéphanie ULg; Heinrichs, Benoît ULg et al

in Journal of Sol-Gel Science and Technology (2003), 26(1-3), 827-830

Pd/SiO2, Ag/SiO2 and Cu/SiO2 xerogel catalysts have been synthesized by cogelation of tetraethoxysilane (TEOS) and chelates of Pd, Ag and Cu with 3-(2-aminoethylamino) propyltrimethoxysilane (EDAS). It ... [more ▼]

Pd/SiO2, Ag/SiO2 and Cu/SiO2 xerogel catalysts have been synthesized by cogelation of tetraethoxysilane (TEOS) and chelates of Pd, Ag and Cu with 3-(2-aminoethylamino) propyltrimethoxysilane (EDAS). It appears that, in cogelled samples, the metal complex acts as a nucleation agent in the formation of silica particles. The resulting catalysts are then composed of completely accessible metallic crystallites with a diameter of about 3 nm located inside silica porous particles with a monodisperse microporous distribution. Xerogels without metal synthesized with EDAS and TEOS (C. Alie, R. Pirard, A. J. Lecloux, and J.-P. Pirard, J. Non-Cryst. Solids 289, 88 (2001)) verify this hypothesis of nucleation by EDAS. [less ▲]

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See detailEtude rétrospective de quarante et un cas d’insuffisance mitrale chez le cheval (1995-2001).
Maurin, Emmanuel; Amory, Hélène ULg; Sandersen, Charlotte ULg

in Pratique Vétérinaire Equine (2003), 35

Une étude rétrospective portant sur quarante et un chevaux qui présentent une insuffisance cardiaque mitrale a été réalisée afin de mieux décrire cette affection et de préciser les répercussions médicales ... [more ▼]

Une étude rétrospective portant sur quarante et un chevaux qui présentent une insuffisance cardiaque mitrale a été réalisée afin de mieux décrire cette affection et de préciser les répercussions médicales et sportives liées à cette maladie. L'insuffisance mitrale est diagnostiquée grâce à des examens cliniques et échographiques, puis un questionnaire (évolution clinique et sportive) est adressé aux propriétaires des animaux. L’analyse de ces dossiers permet en particulier d’évaluer, d'une part, l’existence d’une association entre les signes d’insuffisance cardiaque congestive et certaines lésions cardio-vasculaires (lésions valvulaires, dilatation de l’atrium gauche, etc.) ou d'autres symptômes (fibrillation auriculaire, etc.), d'autre part, d’apprécier la corrélation éventuelle entre ces différents symptômes ou lésions et la survie des chevaux affectés. Les résultats ainsi que les biais possibles de cette étude sont ensuite discutés. [less ▲]

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See detailLa varicelle et le zona ou les mystères de la latence d'un virus et de sa réactivation
Rentier, Bernard ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2003), 158(3-4), 169-73174-5

Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features: chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological ... [more ▼]

Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features: chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological features of these diseases such as complications of chicken pox, viral latency in sensory ganglia and reactivation as shingles with concurrent and possibly subsequent prolonged pain, are the sequels of the invasion of the peripheral nervous system during primary infection. Prevention is achieved by vaccination with a live attenuated virus strain and therapy calls for specific antiviral agents. In many respects, vzv behaves differently from close relatives. In particular, viral latency in the nervous system is basically different from that of other Herpesviridae. The recent discovery of the expression of some viral regulatory proteins during latency, although it had always been considered that vzv latency was silent, and demonstration that these proteins are immunogenic open new avenues concerning the immune control of vzv reactivation. [less ▲]

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See detailPhysiology of reproduction and endocrinology in cervids. A review
Drion, Pierre ULg; Hanzen, Christian ULg; Wirth, Delphine - in memoriam et al

in Annales de Médecine Vétérinaire (2003), 147(5), 291-313

Knowledge about cervids are rapidly growing. This work aims to present the more recent scientific information on reproductive physiology and endocrinology of the cervids: anatomy of the genital tract ... [more ▼]

Knowledge about cervids are rapidly growing. This work aims to present the more recent scientific information on reproductive physiology and endocrinology of the cervids: anatomy of the genital tract, length of breeding season, parameters and endocrinology of the reproductive cycle, endocrinology of pregnancy. It also aims to highlight differences between cervids and domestic ruminants such as embryonic diapause observed in Capreolus capreolus. [less ▲]

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See detailIndo-iranien *aruna
Swennen, Philippe ULg

in Journal Asiatique (2003), 291

In sanskrit, aruna- means "red, pink". In Avestan, occidental scholars translate auruna by "wild". Nothing explains this paradox between two words whose etymological equivalence is obvious. A precise ... [more ▼]

In sanskrit, aruna- means "red, pink". In Avestan, occidental scholars translate auruna by "wild". Nothing explains this paradox between two words whose etymological equivalence is obvious. A precise reading of the Rig-Vedic stanzas shows that the feminine form of this adjective always qualifies the Dawn. This systematic use modified the meaning of the adjective. Beyond its chromatic value, it indicates in the Rigvedic poetries the intermediate time linking day and night. [less ▲]

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See detailEnquête sur les "contes" de Voltaire (II)
Tilkin, Françoise ULg

in Cahiers Voltaire : Revue Annuelle de la Société Voltaire (2003), 2

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See detailMathematical modelling and design of an advanced once-through heat recovery steam generator
Dumont, Marie-Noëlle ULg; Heyen, Georges ULg

in Computer Aided Chemical Engineering (2003), 14

The once-through heat recovery steam generator design is ideally matched to very high temperature and pressure, well into the supercritical range. Moreover this type of previous termboilernext term is ... [more ▼]

The once-through heat recovery steam generator design is ideally matched to very high temperature and pressure, well into the supercritical range. Moreover this type of previous termboilernext term is structurally simpler than a conventional one, since no drum is required. A specific mathematical model has been developed. Thermodynamic model has been implemented to suit very high pressure (up to 240 bar), sub- and supercritical steam properties. We illustrate the model use with a 180 bar once-through previous termboilernext term (OTB). [less ▲]

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See detailRadiothérapie externe accélérée postopératoire des carcinomes épidermoïdes localement évolués de la sphère ORL : étude prospective de phase II
Zouhair, A; COUCKE, Philippe ULg; Azria, D. et al

in Bulletin du Cancer. Radiothérapie : Journal de la Société Française du Cancer : Organe de la Société Française de Radiothérapie Oncologique (2003), 7

Abstract Purpose. – To assess the feasibility and efficacy of accelerated postoperative radiation therapy (RT) in patients with squamous-cell carcinoma of the head and neck (SCCHN). Patients and methods ... [more ▼]

Abstract Purpose. – To assess the feasibility and efficacy of accelerated postoperative radiation therapy (RT) in patients with squamous-cell carcinoma of the head and neck (SCCHN). Patients and methods. – Between December 1997 and July 2001, 68 patients (male to female ratio: 52/16; median age: 60-years (range: 43–81) with pT1-pT4 and/or pN0-pN3 SCCHN (24 oropharynx, 19 oral cavity, 13 hypopharynx, 5 larynx, 3 unknown primary, 2 maxillary sinus, and 2 salivary gland) were included in this prospective study. Postoperative RT was indicated because extracapsular infiltration (ECI) * Auteur correspondant. Adresse e-mail : abderrahim.zouhair@chuv.hospvd.ch (A. Zouhair). Cancer/Radiothérapie 7 (2003) 231–236 www.elsevier.com/locate/canrad © 2003 Éditions scientifiques et médicales Elsevier SAS. Tous droits réservés. doi:10.1016/S1278-3218(03)00041-6 was observed in 20 (29%), positive surgical margins (PSM) in 20 (29%) or both in 23 patients (34%). Treatment consisted of external beam RT 66 Gy in 5 weeks and 3 days. Median follow-up was 15 months. Results. – According to CTC 2.0, acute morbidity was acceptable: grade 3 mucositis was observed in 15 (22%) patients, grade 3 dysphagia in 19 (28%) patients, grade 3 skin erythema in 21 (31%) patients with a median weight loss of 3.1 kg (range: 0–16). No grade 4 toxicity was observed. Median time to relapse was 13 months; we observed only three (4%) local and four (6%) regional relapses, whereas eight (12%) patients developed distant metastases without any evidence of locoregional recurrence. The 2 years overall-, disease-free survival, and actuarial locoregional control rates were 85, 73 and 83% respectively. Conclusion. – The reduction of the overall treatment time using postoperative accelerated RT with weekly concomitant boost (six fractions per week) is feasible with local control rates comparable to that of published data. Acute RT-related morbidity is acceptable. [less ▲]

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See detailPetrogenesis of jotunitic and acidic members of an AMC suite (Rogaland anorthosite province, SW Norway): a Sr and Nd isotopic assessment
Bolle, Olivier ULg; Demaiffe, Daniel; Duchesne, Jean-Clair ULg

in Precambrian Research (2003), 124(2-4), 185-214

Sr and Nd isotopic data from the anorthosite-mangerite-charnockite (AMC) suite of the Late-Sveconorwegian (ca. 0.93 Ga) Rogaland anorthosite province of SW Norway are discussed. The study focuses on new ... [more ▼]

Sr and Nd isotopic data from the anorthosite-mangerite-charnockite (AMC) suite of the Late-Sveconorwegian (ca. 0.93 Ga) Rogaland anorthosite province of SW Norway are discussed. The study focuses on new data obtained from three distinct rock occurrences: (1) primitive (=MgO-rich and K2O-poor)jotunites that represent the parental magmas of leuconorite and mafic plutons (Sr-87/Sr-86(0.93Ga) = ca. 0.704-0.707, epsilon(Nd)(0.93 Ga) = +3.6 down to +1.2); (2) evolved jotunites that differentiated from the primitive jotunites and constitute the starting components of dyke-scale fractionation trends (Sr-87/Sr-86(0.93Ga) = ca. 0.705-0.713, epsilon(Nd)(0.93 Ga) = +0.4 down to -2.0); and (3) felsic plutons (Sr-87/Sr-86(0.93Ga) = ca. 0.707-0.723, epsilon(Nd)(0.93Ga) = +1.4 down to -1.7). A comparison of the Sr and Nd isotopic compositions with available geochemical data (major and trace elements) is also made. Fractionation of the primitive to the evolved jotunites, below the intrusion level of the anorthosite province, is shown to have involved crustal contamination. A case of fractional crystallization and simultaneous contamination/assimilation is substantiated in the felsic cap of a layered intrusion (the Bjerkreim-Sokndal intrusion). It is further proposed that the Sr and Nd isotopic compositions of the various felsic occurrences result from fractional crystallization of primitive jotunitic melts, with or without contamination/assimilation; this strengthens the possibility for large volumes of silica-rich magmas to have been produced by fractionation, through evolved jotunites, of primitive jotunites. The entire range in Sr and Nd isotopic compositions of the Rogaland anorthosite province is interpreted as reflecting a mixing of crustal contaminants, having variable Sr-87/Sr-86(0.93Ga) ratios and (negative) epsilon(Nd)(0.93 Ga) values, with a more isotopically primitive source. The crustal end members of that mixing array are represented by moderatey to strongly LILE-enriched high-grade gneisses from the Pre-Sveconorwegian basement of southernmost Norway, that have a crustal history extending back to 1.5-1.9 Ga in the surroundings of the anorthosite province. The primitive end member is either an unusual LREE-depleted and Rb-enriched component, possibly corresponding to an originally depleted source subsequently modified by metasomatic fluids, or a more classical depleted component; it corresponds to a gabbronoritic rock of the deep crust, as shown by recent experimental data, with a quite short crustal residence time (<0.4-0.2 Ga). If that mafic end member is the lower granulitic crust itself, this would imply the presence in the deep continental crust of southwesternmost Norway of a crustal material strongly different from the 1.7- to 1.9-Gyr-old, moderately LILE-enriched component that is supposed to constitute the largest volume of the present deep continental crust in southern Norway. (C) 2003 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailHaplotype sharing refines the location of an imprinted quantitative trait locus with major effect on muscle mass to a 250-kb chromosome segment containing the porcine IGF2 gene
Nezer, C.; Collette, C.; Moreau, L. et al

in Genetics (2003), 165(1), 277-285

We herein describe the fine mapping of an imprinted QTL with major effect on muscle mass that was previously assigned to distal SSC2p in the pig. The proposed approach exploits linkage disequilibrium in ... [more ▼]

We herein describe the fine mapping of an imprinted QTL with major effect on muscle mass that was previously assigned to distal SSC2p in the pig. The proposed approach exploits linkage disequilibrium in combination with QTL genotyping by marker-assisted segregation analysis. By identifying a haplotype shared by all "Q" chromosomes, we map the QTL to an approximately 250-kb chromosome segment containing INS and IGF2 as the only known paternally expressed genes. This considerably reinforces the candidacy of these genes, justifying their detailed analysis. [less ▲]

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See detailAccuracy of the continuous glucose monitoring system in inpatient and outpatient conditions
Djakouré-Platonoff, C.; RADERMECKER, Régis ULg; Reach, G. et al

in Diabètes & Métabolism (2003), 29

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See detailComparison of aquifer vulnerability assessment techniques. Application to the Neblon river basin (Belgium)
Gogu, Radu Constantin; Hallet, Vincent; Dassargues, Alain ULg

in Environmental Geology (2003), 44(8), 881-892

Five different methods for assessing intrinsic aquifer vulnerability were tested in a case study and their results compared. The test area was a slightly karstified district in the Condroz region of ... [more ▼]

Five different methods for assessing intrinsic aquifer vulnerability were tested in a case study and their results compared. The test area was a slightly karstified district in the Condroz region of Belgium. The basin covers about 65 km(2) and the karst aquifer provides a water-supply of about 28,000 m(3)d(-1). The methods tested were: EPIK (Doerfliger et al. 1999), DRASTIC (Aller et al.1987), 'German method' (von Hoyer and Sofner 1998), GOD (Foster 1987) and ISIS (Civita and De Regibus 1995). The results are compared and critically examined. From the analysis, it seems that reducing the number of parameters is unsatisfactory, due to the variety of geological conditions. The various methods produce very different results at any given site. As only physically-based methods can be checked for their reliability, it is clear that future vulnerability mapping techniques must incorporate such methods. [less ▲]

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See detailEffect of somatic growth, strain and sex on double-chamber plethymosgraphic respiratory function values in healthy mice
Flandre, Th.; Leroy, Pascal ULg; Desmecht, Daniel ULg

in Journal of Applied Physiology (2003), 94(3), 1129-1136

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See detailEffet de la durée d’application d’un stimulus gravitationnel sur la formation de bois de tension et de bois opposé dans de jeunes pousses de peuplier (Populus euramericana cv ‘Ghoy’)
Jourez, Benoît ULg; Avella-Shaw, Thomas

in Annals of Forest Science : a Multidisciplinary and International Journal (2003), 60

De jeunes pousses de Peuplier Ghoy ont été maintenues artificiellement inclinées pendant des durées croissantes, afin d’induire la formation de tissus de bois de tension et de bois opposé en réaction au ... [more ▼]

De jeunes pousses de Peuplier Ghoy ont été maintenues artificiellement inclinées pendant des durées croissantes, afin d’induire la formation de tissus de bois de tension et de bois opposé en réaction au stimulus gravitationnel. Il apparaît que ces pousses sont susceptibles de percevoir et de réagir à un stimulus extrêmement bref à l’échelle d’une période de végétation. Après un temps de présentation de 6 heures, l’ensemble des pousses ont formé un arc de bois opposé. Toutefois, sur la face supérieure, un temps compris entre 24 et 48 heures est nécessaire pour qu’elles perçoivent la modification de leur état d’équilibre et se mettent à former du bois de tension. Après un temps de latence de 48 heures, la formation de fibres gélatineuses est déjà observée sur la face supérieure des tiges. L’augmentation de la durée du stimulus a des répercussions sur le nombre de fibres gélatineuses et sur l’angle d’ouverture de l’arc de bois de tension. Sur la face inférieure, les fibres de bois opposé se forment à un rythme moins soutenu, conduisant à une excentricité de la moelle dans la section de la tige. Le redressement des pousses est effectif après une durée de stimulus comprise entre 4 et 8 jours. [less ▲]

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See detailRooting blockage in the tobacco rac mutant occurs at the initiation phase, and induces diversion to xylem differentiation
Faivre-Rampant, Odile; D'Angeli, S.; Falasca, G. et al

in Plant Biosystems (2003), 137(2), 163-174

The rac mutant of Nicotiana tabacum L. cv. Xanthii is impaired in adventitious root formation. The objective of the present study was to determine whether or not the root induction phase occurs in the rac ... [more ▼]

The rac mutant of Nicotiana tabacum L. cv. Xanthii is impaired in adventitious root formation. The objective of the present study was to determine whether or not the root induction phase occurs in the rac mutant, and if so, to determine what causes the induced cells to become incapable of organising root primordia. To this end, rac and wild-type shoots were cultured in vitro for 7 days under conditions suitable for obtaining roots in the wild-type (i.e., exposure to 5 muM indole-3-butyric acid for 4 h, and then transfer to hormone-free medium), and then histologically and biochemically analysed during culture. The variations in peroxidase activity, and in cellular levels of auxins and polyamines revealed that the induction phase occurs in rac shoots, although it lasts longer than in the wild-type ones. Furthermore, both auxin and polyamines were consistently higher in rac shoots compared to the wild-type. After induction, auxin and putrescine levels abruptly decreased in the wild-type shoots, whereas they decreased much more slowly in the rac mutant. The histological analysis of the wild-type shoots showed that the abrupt decrease in auxin and polyamine levels were correlated with a normal initiation phase. In fact, wild-type shoots showed cell divisions in the procambium already at day 2, resulting in the formation of root primordia at day 4, and in root emergence between days 5 and 7. In rac shoots, despite the fact that the procambium cells were activated to undergo cell division, the initiation phase was highly perturbed, and the procambial cells developed tracheary elements instead of adventitious roots. The different morphogenic responses of the two genotypes are discussed in the light of the differences in auxin content after the induction phase. [less ▲]

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See detailCharacterisation of different inulin samples by DSC - Influence of polymerisation degree on melting temperature
Blecker, Christophe ULg; Chevalier, J. P.; Fougnies, C. et al

in Journal of Thermal Analysis & Calorimetry (2003), 71(1), 215-224

Melting behaviour of powder inulin has been studied by differential scanning calorimetry. DSC curves show two endothermic peaks, relative to water elimination and to inulin melting, respectively. The ... [more ▼]

Melting behaviour of powder inulin has been studied by differential scanning calorimetry. DSC curves show two endothermic peaks, relative to water elimination and to inulin melting, respectively. The second peak is dependent on inulin type and a shift to a higher temperature is observed with increasing average polymerisation degree (DP) of the sample. For similar crystallinity index, linear relations have been underlined and so predicting inulin mean DP can be done by DSC analysis. The study shows that a relatively high heating rate (25degreesC min(-1)) can be used and brings a supplementary interest by an important reduction of analysis time. [less ▲]

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See detailDesioratadine: Safety and tolerability data in clinical practice
Borchard, U. H. J.; Daly, Adrian ULg; Plenker, A.

in Journal of Allergy and Clinical Immunology (The) (2003), 111(1), 74

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See detailL'image du mois. Un chancre mou.
Nikkels, Arjen ULg; Arrese Estrada, Jorge ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2003), 58(2), 64-6

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See detailL’implication dans la recherche clinique : un chemin vers la psychanalyse
Naziri, Despina ULg

in Revue Belge de Psychanalyse (2003), 40(printemps), 3-24

L'article débute par un bref rappel des liens entre psychologie clinique et modèle psychanalytique et de la spécificité de la recherche clinique. Puis j’illustrerai ce type de recherche à travers mon ... [more ▼]

L'article débute par un bref rappel des liens entre psychologie clinique et modèle psychanalytique et de la spécificité de la recherche clinique. Puis j’illustrerai ce type de recherche à travers mon travail sur le recours répétitif à l’avortement en explicitant mon cheminement, tant au niveau de la pensée que de l’expérience, et en reprenant quelques repères de mon itinéraire personnel. [less ▲]

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See detailCalorimetry of cationic liposome-DNA complex and intracellular visualization of the complexes.
Elouahabi, Abdelatif; Thiry, Marc ULg; Pector, Veronique et al

in Methods in Enzymology (2003), 373

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See detailLe monument à Léopold Ier: approche architecturale et typologique
Houbart, Claudine ULg

in Bulletin de la Classe des Beaux-Arts (2003)

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See detailAlong or across front ocean survey strategy? The estimation of quasi-geostrophic vertical velocities and temperature fluxes
Rixen, Michel; Allen, J. T.; Pollard, R. T. et al

in Geophysical Research Letters (2003), 30(5), 61-68

In a companion paper we have shown that at the mesoscale, the unusual across front sampling strategy (AL) is more accurate than the usual across front sampling strategy (AC) on hydrographic and bio ... [more ▼]

In a companion paper we have shown that at the mesoscale, the unusual across front sampling strategy (AL) is more accurate than the usual across front sampling strategy (AC) on hydrographic and bio-chemical properties when the front is sufficiently developed. The cruise design based on the optimal reconstruction of the density fields does however not imply that derived variables like quasi-geostrophic (QG) vertical velocities and temperature fluxes also exhibit minimal associated errors. Here we present results of optimized sampling strategies for diagnostic QG vertical velocities (wQG) and temperature fluxes (θQG) derived from the omega equation. Results are illustrated in the same framework, for the Iceland-Faroes oceanic frontal area and for a control model and reveal that at these spatio-temporal scales, the unusual AL may also provide better estimations of vertical velocities and temperature fluxes compared to the classic AC, especially when the front is sufficiently developed. [less ▲]

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See detailCent ans de géographie humaine à Liège
Schmitz, Serge ULg

in Bulletin de la Société Géographique de Liège (2003), 43

Numéro spécial édité à l'occasion du centenaire de l'enseignement et de la géographie à l'Université de Liège et comportant les contributions des responsables des divers services de géographie au sein de ... [more ▼]

Numéro spécial édité à l'occasion du centenaire de l'enseignement et de la géographie à l'Université de Liège et comportant les contributions des responsables des divers services de géographie au sein de l'Université de Liège. [less ▲]

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See detailFraming the future of antifungals in atopic dermatitis.
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Dermatology : International Journal for Clinical & Investigative Dermatology (2003), 206(4), 398-400

Atopic dermatitis (AD) is a frequent chronic inflammatory skin disease. Some fungal colonization or infection of the skin may exacerbate AD severity, particularly the so-called head and neck variant. In ... [more ▼]

Atopic dermatitis (AD) is a frequent chronic inflammatory skin disease. Some fungal colonization or infection of the skin may exacerbate AD severity, particularly the so-called head and neck variant. In addition, excessive intestinal colonization by Candida albicans may represent an additional triggering factor. Hence, there is a rationale to use antifungals in selected AD patients. Early trials with topical ketoconazole in head and neck AD showed a decrease in Malassezia colonization, but no significant improvement was observed in the clinical severity. In contrast, clinical improvement and decreased serum IgE were obtained in patients with positive Malassezia radioallergosorbent tests (RASTs) who were treated by oral ketoconazole. Some preliminary data suggested that oral itraconazole treatment in AD patients reduced the need for topical corticosteroids, provided clinical improvement particularly in head and neck AD, reduced the cutaneous and intestinal fungal colonization that may trigger AD, reduced the percentage of positive Malassezia cultures and demonstrated a decrease in C. albicans and Malassezia RAST values. Furthermore, beside its antifungal action, itraconazole in part relieves pruritus and inflammation. In conclusion, oral itraconazole treatment can alleviate AD severity in selected patients. Fluconazole is also effective. Further research is warranted to identify whether the load in skin surface fungal agents, the fungal RAST values and specific prick testing should be assessed in order to optimize the antifungal management in AD patients. [less ▲]

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See detailArterial embolization as a treatment of chronic edema following free cutaneous flap transfer to the lower limbs.
Tchuisse, Charlemagne Noukoua; Barah, Ali; NCHIMI LONGANG, Alain ULg et al

in Cardiovascular & Interventional Radiology (2003), 26(3), 316-8

Persisting chronic edema following postoperative free flap transfer is a common complication. We report 3 cases of successful treatment by selective arterial embolization of the feeding arterial branches ... [more ▼]

Persisting chronic edema following postoperative free flap transfer is a common complication. We report 3 cases of successful treatment by selective arterial embolization of the feeding arterial branches without side effect. One session embolization is advocated as a first line treatment of this condition. [less ▲]

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See detailPreoperative hyperfractionated acclerated radiotherapy (HART) and concomittant CPT-11 in advanced rectal carcinoma. A phase I study.
Voelter, V; Stupp, R; Matter, M et al

in International Journal of Radiation, Oncology, Biology, Physics (2003), 56(5), 1288-1294

Purpose: Patients with locally advanced rectal carcinoma are at risk for both local recurrence and distant metastases. We demonstrated the efficacy of preoperative hyperfractionated accelerated ... [more ▼]

Purpose: Patients with locally advanced rectal carcinoma are at risk for both local recurrence and distant metastases. We demonstrated the efficacy of preoperative hyperfractionated accelerated radiotherapy (HART). In this Phase I trial, we aimed at introducing chemotherapy early in the treatment course with both intrinsic antitumor activity and a radiosensitizer effect. Methods and Materials: Twenty-eight patients (19 males; median age 63, range 28–75) with advanced rectal carcinoma (cT3: 24; cT4: 4; cN : 12; M1: 5) were enrolled, including 8 patients treated at the maximally tolerated dose. Escalating doses of CPT-11 (30–105 mg/m2/week) were given on Days 1, 8, and 15, and concomitant HART (41.6 Gy, 1.6 Gy bid 13 days) started on Day 8. Surgery was to be performed within 1 week after the end of radiochemotherapy. Results: Twenty-six patients completed all preoperative radiochemotherapy as scheduled; all patients underwent surgery. Dose-limiting toxicity was diarrhea Grade 3 occurring at dose level 6 (105 mg/m2). Hematotoxicity was mild, with only 1 patient experiencing Grade 3 neutropenia. Postoperative complications (30 days) occurred in 7 patients, with an anastomotic leak rate of 22%. Conclusions: The recommended Phase II dose of CPT-11 in this setting is 90 mg/m2/week. Further Phase II exploration at this dose is warranted. © 2003 Elsevier Inc. [less ▲]

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See detailEffets fonctionnels respiratoires induits par l'inhalation de glycopyrrolate chez le cheval poussif en crise
Art, Tatiana ULg; de Moffarts, Brieuc; Van Erck, Emmanuelle et al

in Annales de Médecine Vétérinaire (2003), 147

Bronchoconstriction is one of the most constant clinical sign observed in heaves-affected horses in crisis. Cholinergic pathways are involved in the occurrence of this obstruction. Consequently ... [more ▼]

Bronchoconstriction is one of the most constant clinical sign observed in heaves-affected horses in crisis. Cholinergic pathways are involved in the occurrence of this obstruction. Consequently anticholinergic drugs are potentially able to improve the pulmonary function of horses in acute crisis. Among these, atropine and ipratropium bromide have been previously experimented and their beneficial effects reported. In the present work, glycopyrrolate, another synthetic anticholinergic molecule has been tested for bronchodilator efficiency in heaves-affected horses. An acute exacerbation of the illness was obtained by a natural challenge with hay and straw in 7 heaves-affected horses. The first day, the reversibility of the bronchospasm of these horses was controlled by intravenous administration of atropine. Then, pulmonary function tests including mechanics of breathing, ie measurement of pleural pressure changes and respiratory airflows, and arterial blond gases analysis, were performed before as well as 15 and 60 minutes alter inhalation of 1500 µg of glycopyrrolate (Robinul®). The crisis induced a dramatic increase of total pulmonary resistance and maximal pleural pressure changes as well as a decrease in dynamic lung compliance. These changes were significantly reversed 15 and 60 minutes after inhalation of glycopyrrolate. We did not observe any adverse effects similar to those classically observed with atropine. These results showed that glycopyrrolate is a very efficient bronchodilator that may be used by the practitioner to treat a heaves-affected horses in crisis [less ▲]

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See detailFoam imbibition in microgravity - An experimental study
Caps, Hervé ULg; Decauwer, H.; Chevalier, M. L. et al

in European Physical Journal B -- Condensed Matter (2003), 33(1), 115-119

We report an experimental study of aqueous foam imbibition in microgravity with strict mass conservation. The foam is in a Hele-Shaw cell. The bubble edge width l is measured by image analysis. The ... [more ▼]

We report an experimental study of aqueous foam imbibition in microgravity with strict mass conservation. The foam is in a Hele-Shaw cell. The bubble edge width l is measured by image analysis. The penetration of the liquid in the foam, the foam imbibition, the foam inflation, and the rigidity loss are shown all to obey strict diffusion processes. The motion of bubbles needed for the foam inflation is a slow two-dimensional process with respect to the one-dimensional capillary rise of liquid. The foam is found to imbibes faster than it inflates. [less ▲]

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See detailCatecholamine and HPA axis dysfunction in depression : relationship with suicidal behavior
Pitchot, William ULg; Reggers, Jean ULg; Pinto, Emmanuel ULg et al

in Neuropsychobiology (2003), 47(3), 152-157

A large body of evidence suggests a potential role for catecholaminergic function as a possible biological factor in the control of suicidal behavior. Recently, we have used a neuroendocrine strategy to ... [more ▼]

A large body of evidence suggests a potential role for catecholaminergic function as a possible biological factor in the control of suicidal behavior. Recently, we have used a neuroendocrine strategy to study dopaminergic and noradrenergic activities in depressed suicide attempters. However, some problems are associated with the use of growth hormone (GH) response to catecholaminergic challenge, because GH release could be decreased by a direct effect of corticosteroids at the pituitary level. Therefore, the purpose of the present study was to assess GH response to both apornorphine, a dopaminergic agonist, and clonidine, an alpha2-adrenergic agonist, according to the dexamethasone suppression test (DST) status in a sample of 20 major depressed inpatients with a history of suicide attempt compared with nonattempters. Our results tended to show that hypercortisolemia as assessed by post-DST cortisol values did not inhibit GH response to apornorphine or clonidine, suggesting that hypothalamo-pituitary-adrenal axis overactivity does not explain the impaired GH response to apornorphine in major depressed patients with a history of suicide attempt. [less ▲]

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See detailHydrodynamique et morphologie d'une bactérie filamenteuse dans un fermenteur à cuve agitée
Groslambert, Sylvie ULg; Blacher, Silvia ULg; Crine, Michel ULg

in Tribune de l'Eau (La) (2003), 56(622), 58-64

Afin d'étudier l'influence de l'hydrodynamique sur une bactérie filamenteuse, Actinomadura R39, nous l'avons cultivée dans un fermenteur de laboratoire de 5 litres à cuve agitée en faisant varier les ... [more ▼]

Afin d'étudier l'influence de l'hydrodynamique sur une bactérie filamenteuse, Actinomadura R39, nous l'avons cultivée dans un fermenteur de laboratoire de 5 litres à cuve agitée en faisant varier les conditions d'agitation. Les variables sont la vitesse de rotation et le type de mobile utilisé: turbines Rushton ou Intermig. Les deux mobiles se distinguent par leur géométrie et par les schémas d'écoulement qu'ils induisent dans la cuve. L'influence de l'hydrodynamique sur Actinomadura R39 est quantifiée par l'évolution de sa morphologie. Cette dernière est estimée par analyse d'images sur des échantillons prélevés lors des cultures. Parallèlement, nous avons caractérisé l'hydrodynamique du fermenteur dans un milieu artificiel reproduisant la rhéologie des fermentations en mesurant la puissance dissipée et en effectuant des essais de traceurs. Ces derniers sont utilisés pour la modélisation du fermenteur par un modèle compartimenté et le calcul du temps de mélange. Nous avons pu ainsi mettre en relation les modifications de la morphologie et des grandeurs caractérisant les écoulements dans le fermenteur. L'existence de corrélations entre les paramètres du modèle et la morphologie a également permis une validation de la signification physique de ce modèle. [less ▲]

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See detailLes protéines de choc thermique (heat shock proteins). II Les protéines de choc thermique (heat shock proteins). II. Hsp70, biomarqueur, bioprotecteur.
Wirth, Delphine; Gustin, Pascal ULg; Drion, Pierre ULg et al

in Annales de Médecine Vétérinaire (2003), 147(2), 127-144

The exposure of any organism to high temperature induces rapid and transient cellular overexpression of specific proteins, the heat shock proteins (Hsps). This response, called heat shock response, was ... [more ▼]

The exposure of any organism to high temperature induces rapid and transient cellular overexpression of specific proteins, the heat shock proteins (Hsps). This response, called heat shock response, was initially discovered in Drosophila. The genes hsps were among the first eukaryotic genes to be cloned and whose regulation, which involves activation of heat shock factor (HSF), was elucidated. More recently, study of Hsp functions, particularly Hsp70, started. Their protective role, related to their molecular chaperon function, was inferred from experiments showing that Hsp70 expression, induced by a first stress, results in a cellular tolerance to second stress. Better understanding of the heat shock response had led to the development of two search fields on Hsp70 expression : (1) its use as biomarker of cellular stress and (2) the exploitation of its cytoprotective functions against various insults. This review includes historic of the research on the heat shock response, description of regulation mechanism of Hsp70 expression, and the interesting perspectives allocated to Hsp70 as biomarker and therapeutic tool. ----------- L’exposition de tout organisme à des températures élevées induit l'expression cellulaire rapide et transitoire de protéines spécifiques, les protéines de choc thermique (Hsps pour " heat shock proteins "). Cette réponse des cellules au choc thermique ou " heat shock response " a été initialement découverte chez la drosophile. Les gènes hsps furent parmi les premiers gènes eucaryotes à être clonés et utilisés comme paradigme dans l'étude des mécanismes de régulation transcriptionnelle faisant intervenir l'activation d'un ou plusieurs " heat shock factors" (HSFs). C'est plus récemment que l'étude des fonctions des Hsps, particulièrement Hsp70, a débuté. Le rôle protecteur de celle-ci, lié à sa fonction de " chaperon " protéique, a été déduit d'expériences montrant que l'induction de l'expression de Hsp70 lors d'un stress était associée au développement d'une tolérance cellulaire vis-à-vis d'un stress ultérieur. En plus d'un intérêt fondamental pour la compréhension de la "réponse au choc thermique", deux axes de recherche appliquée se sont développés visant à investiguer la possibilité d'utiliser l'expression de Hsp70 comme biomarqueur de souffrance cellulaire d'une part et, d'autre part, d'exploiter ses fonctions comme moyen de protection des cellules contre divers types d'agressions. Cette revue décrit l'historique des découvertes sur la " réponse au choc thermique ", le mécanisme régulant l'expression de Hsp70 ainsi que les perspectives intéressantes s'ouvrant à l'utilisation de l'expression de Hsp70 en tant que biomarqueur et outil thérapeutique. [less ▲]

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