References of "Article"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailPharmacological evaluation of the novel thromboxane modulator BM-567 (II/II). Effects of BM-567 on osteogenic sarcoma-cell-induced platelet aggregation
De Leval, X.; Benoit, V.; Delarge, J. et al

in Prostaglandins, Leukotrienes, and Essential Fatty Acids (2003)

Detailed reference viewed: 21 (3 ULiège)
Full Text
Peer Reviewed
See detailHybrid magnetic equivalent circuit - finite element modelling of transformer fed electrical machines
Gyselinck, Johan; Dular, Patrick ULiege; Legros, Willy ULiege et al

in Compel-the International Journal for Computation and Mathematics in Electrical and Electronic Engineering (2003), 22(3), 643-658

This paper deals with the modelling of transformer supply in the two-dimensional (2D) finite element (FE) simulation of rotating electrical machines. Three different transformer models are compared The ... [more ▼]

This paper deals with the modelling of transformer supply in the two-dimensional (2D) finite element (FE) simulation of rotating electrical machines. Three different transformer models are compared The reference one is based on two 2D FE models, considering a cross-section either parallel or perpendicular to the laminations of the magnetic core. The parameters of the two other transformer models, a magnetic equivalent circuit and an electrical equivalent circuit, can be derived from the reference model Particular attention is paid to some common features of the transformer models, e.g. with regard to the inclusion of iron losses. The three models are used in the 2D FE simulation of the steady-state load operation and the starting from stand-still of an induction motor. [less ▲]

Detailed reference viewed: 33 (0 ULiège)
Full Text
Peer Reviewed
See detail3-Isopropylamino-7-nitro-1,4,2-benzodithiazine 1,1-dioxide
Dupont, L.; Somers, F.; De Tullio, Pascal ULiege et al

in Acta Crystallographica (2003)

Detailed reference viewed: 25 (0 ULiège)
Full Text
Peer Reviewed
See detailRadiothérapie externe accélérée postopératoire des carcinomes épidermoïdes localement évolués de la sphère ORL : étude prospective de phase II
Zouhair, A; COUCKE, Philippe ULiege; Azria, D. et al

in Bulletin du Cancer. Radiothérapie : Journal de la Société Française du Cancer : Organe de la Société Française de Radiothérapie Oncologique (2003), 7

Abstract Purpose. – To assess the feasibility and efficacy of accelerated postoperative radiation therapy (RT) in patients with squamous-cell carcinoma of the head and neck (SCCHN). Patients and methods ... [more ▼]

Abstract Purpose. – To assess the feasibility and efficacy of accelerated postoperative radiation therapy (RT) in patients with squamous-cell carcinoma of the head and neck (SCCHN). Patients and methods. – Between December 1997 and July 2001, 68 patients (male to female ratio: 52/16; median age: 60-years (range: 43–81) with pT1-pT4 and/or pN0-pN3 SCCHN (24 oropharynx, 19 oral cavity, 13 hypopharynx, 5 larynx, 3 unknown primary, 2 maxillary sinus, and 2 salivary gland) were included in this prospective study. Postoperative RT was indicated because extracapsular infiltration (ECI) * Auteur correspondant. Adresse e-mail : abderrahim.zouhair@chuv.hospvd.ch (A. Zouhair). Cancer/Radiothérapie 7 (2003) 231–236 www.elsevier.com/locate/canrad © 2003 Éditions scientifiques et médicales Elsevier SAS. Tous droits réservés. doi:10.1016/S1278-3218(03)00041-6 was observed in 20 (29%), positive surgical margins (PSM) in 20 (29%) or both in 23 patients (34%). Treatment consisted of external beam RT 66 Gy in 5 weeks and 3 days. Median follow-up was 15 months. Results. – According to CTC 2.0, acute morbidity was acceptable: grade 3 mucositis was observed in 15 (22%) patients, grade 3 dysphagia in 19 (28%) patients, grade 3 skin erythema in 21 (31%) patients with a median weight loss of 3.1 kg (range: 0–16). No grade 4 toxicity was observed. Median time to relapse was 13 months; we observed only three (4%) local and four (6%) regional relapses, whereas eight (12%) patients developed distant metastases without any evidence of locoregional recurrence. The 2 years overall-, disease-free survival, and actuarial locoregional control rates were 85, 73 and 83% respectively. Conclusion. – The reduction of the overall treatment time using postoperative accelerated RT with weekly concomitant boost (six fractions per week) is feasible with local control rates comparable to that of published data. Acute RT-related morbidity is acceptable. [less ▲]

Detailed reference viewed: 319 (12 ULiège)
Full Text
Peer Reviewed
See detailLa climatologie
Erpicum, Michel ULiege; Alexandre, Jean ULiege

in Bulletin de la Société Géographique de Liège (2003), 43(2003), 79-88

Detailed reference viewed: 56 (9 ULiège)
Full Text
Peer Reviewed
See detailMeasure Noun constructions : an instance of semantically-driven grammaticalization
Brems, Lieselotte ULiege

in International Journal of Corpus Linguistics (2003), 8(2), 283-312

Detailed reference viewed: 84 (3 ULiège)
Full Text
Peer Reviewed
See detailInvestigation of the inhibition mechanism of coumarins on chymotrypsin by mass spectrometry
Pochet, L.; Dieu, M.; Frederick, R. et al

in Tetrahedron (2003)

Detailed reference viewed: 23 (2 ULiège)
Full Text
Peer Reviewed
See detailLa Belgique francophone face au référendum sarrois de 1955
Lanneau, Catherine ULiege

in Revue d'Allemagne et des Pays de Langue Allemande (2003), 35(4), 525-545

Since 1945, French-speaking Belgians were looking at the « Saar problem », stumbling block of Europe’s build-up, with a mixture of awe and hope. In 1955, as the inhabitants were asked to vote on a ... [more ▼]

Since 1945, French-speaking Belgians were looking at the « Saar problem », stumbling block of Europe’s build-up, with a mixture of awe and hope. In 1955, as the inhabitants were asked to vote on a peculiar status of “Europeanised” autonomous territory (within the WEU but keeping economical union with France), the coming plebiscite was seen as a good bid on Europe’s future. At first, Belgian public opinion was under the influence of optimistic statements made by official French and autonomist propaganda. After the failure of the plebiscite, Belgian journalists and diplomats tried to find some simple and often rather bombastic explanations: intern and extern weakness of France seen as over-cautious or tinted with europhobia, lack of appeal of the European idea, attractiveness of the German economical bloom, Nazi nostalgia or even perennial nationalism of the German man. Then, Saarland, having refused to be an oddity in a nation-based Europe, fell from public interest into oblivion... [less ▲]

Detailed reference viewed: 84 (13 ULiège)
Full Text
Peer Reviewed
See detailAmphiphilic copolymers of epsilon-caprolactone and gamma-substituted epsilon-caprolactone. Synthesis and functionalization of poly(D,L-lactide) nanoparticles
Gautier, Sandrine; D'Aloia, Violetta; Halleux, Olivier et al

in Journal of Biomaterials Science. Polymer Edition (2003), 14(1), 63-85

Fully biodegradable and surface-functionalized poly(D,L-lactide) (PLA) nanoparticles have been prepared by a co-precipitation technique. Novel amphiphilic random copolyesters P(CL-co-gamma XCL) were ... [more ▼]

Fully biodegradable and surface-functionalized poly(D,L-lactide) (PLA) nanoparticles have been prepared by a co-precipitation technique. Novel amphiphilic random copolyesters P(CL-co-gamma XCL) were synthesized by controlled copolymerization of epsilon-caprolactone and epsilon-caprolactone substituted in the gamma-position by a hydrophilic X group, where X is either a cationic pyridinium (gamma-Py-CL) or a non-ionic hydroxyl (gamma-OH-CL). Nanoparticles were prepared by co-precipitation of PLA with the P(CL-co-gamma-XCL) copolyester from a DMSO solution. Small amounts of cationic P(CL-co-gamma-Py-CL) copolymers are needed to quantitatively form stable nanoparticles (ca. 10 mg/100 mg PLA), although larger amounts of non-ionic P(CL-co-gamma-OH-CL) copolymers are needed (ges12.5 mg/100 mg PLA). Copolymers with a low degree of polymerization (ca. 40) are more efficient stabilizers, probably because of faster migration towards the nanoparticle-water interface. The nanoparticle diameter decreases with the polymer concentration in DMSO, e.g. from ca. 160 nm (16 mg/ml) to ca. 100 nm (2 mg/ml) for PLA/P(CL-co-gamma-Py-CL) nanoparticles. Migration of the P(CL-co-gamma-XCL) copolyesters to the nanoparticle surface was confirmed by measurement of the zeta potential, i.e. ca. +65 mV for P(CL-co-gamma-Py-CL) and -7 mV for P(CL-co-gamma-OH-CL). The polyamphiphilic copolyesters stabilize PLA nanoparticles by electrostatic or steric repulsions, depending on whether they are charged or not. They also impart functionality and reactivity to the surface, which opens up new opportunities for labelling and targeting purposes. [less ▲]

Detailed reference viewed: 56 (4 ULiège)
Full Text
Peer Reviewed
See detailExamen de jurisprudence (1995-2001). Contrat de travail
Kefer, Fabienne ULiege; Clesse, Jacques ULiege

in Revue Critique de Jurisprudence Belge (2003)

Detailed reference viewed: 52 (17 ULiège)
Full Text
Peer Reviewed
See detailEvaluation of two commercial solid-phase microextraction fibres for the analysis of target aroma compounds in cooked beef meat
Machiels, D.; Istasse, Louis ULiege

in Talanta (2003), 61(4), 529-537

The aroma profile of cooked beef meat has been investigated by solid-phase microextraction (SPME) combined with gas chromatography-mass spectrometry (GC-MS). Out of more than 200 volatile compounds, 36 ... [more ▼]

The aroma profile of cooked beef meat has been investigated by solid-phase microextraction (SPME) combined with gas chromatography-mass spectrometry (GC-MS). Out of more than 200 volatile compounds, 36 key odour-active compounds were selected for analysis. Several extraction times, desorption times, temperature conditions and fibre types were tested to achieve a fast and reproducible extraction, and a representative analysis of the aroma profile of cooked beef. Extraction conditions and fibre type significantly affected the majority of the target compounds. Divinylbenzene-carboxen-polydimethylsiloxane (DVB-CAR-PDMS) fibre presented a better reproducibility at all extraction times and extracted more efficiently the less volatile compounds than the carboxen-polydimethylsiloxane (CAR-PDMS) fibre. The high molecular weight compounds seemed to achieve faster the equilibrium between the headspace and DVB-CAR-PDMS fibre. The use of SPME was shown to be a simple, sensitive, selective, representative, fast, and low-cost method for the evaluation of key odour-active compounds in cooked beef meat, even if further research on quantitative analysis of volatiles using SPME on solid samples has to be done. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

Detailed reference viewed: 25 (1 ULiège)
Full Text
Peer Reviewed
See detailSHIP2 et signalisation de l'insuline: quel role dans la pathogenese et le traitement du diabete de type 2?
Schurmans, Stéphane ULiege

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2003), 158(7-9), 335-9

Based on the analysis of SHIP2+/- and SHIP2-/- mice showing that the lipid phophatase SHIP2 is an important negative regulator of the insulin pathway, we have suggested that the enzyme is a candidate gene ... [more ▼]

Based on the analysis of SHIP2+/- and SHIP2-/- mice showing that the lipid phophatase SHIP2 is an important negative regulator of the insulin pathway, we have suggested that the enzyme is a candidate gene for genetic predisposition to type 2 diabetes, and a potential therapeutic target for the same disease. Two years after, we propose to review these hypothesis in light of recent results from our laboratory, from international collaborations and from competitors in the field. [less ▲]

Detailed reference viewed: 24 (2 ULiège)
Full Text
Peer Reviewed
See detailRestart of lignification in micropropagated walnut shoots coincides with rooting induction
Bisbis, Badia; Kevers, Claire ULiege; Crèvecoeur, Michèle et al

in Biologia Plantarum (2003), 47(1), 1-5

The lignin content of walnut shoots did not change during in vitro shoot Multiplication. Lignin content started to increase as soon as shoots were passed to a rooting medium with auxin. Exogenous auxin ... [more ▼]

The lignin content of walnut shoots did not change during in vitro shoot Multiplication. Lignin content started to increase as soon as shoots were passed to a rooting medium with auxin. Exogenous auxin (applied for rooting) Caused a transient elevation of the endogenous free indoleacetic acid (IAA) content with a Simultaneous decrease of peroxidase activity. These events typically marked the completion of the rooting inductive phase (before any visible histological event. that is before the cell divisions beginnin- the rootin- initiation phase). This meant that either the given exogenous auxin or the endogenous IAA has served as signal for the stimulation of lignification. Continued increase of lignification in the shoots required completion of root formation; this increase indeed was slown down when root emergence did not occur. It was further shown that lionification varied conversely to the content of the Soluble Phenol Content. itself apparently being related to the activity of phenylalanine ammonia-lyase activity. [less ▲]

Detailed reference viewed: 79 (4 ULiège)
Full Text
See detailA propos de la prescription des mensualités d'un crédit
Biquet, Christine ULiege

in Annuaire juridique du crédit et du règlement collectif de dettes (2003)

Detailed reference viewed: 60 (2 ULiège)
Full Text
Peer Reviewed
See detailEffect of induction of late embryonic mortality on plasma profiles of pregnancy associated glycoprotein 1 in heifers
Szenci, Otto; Beckers, Jean-François ULiege; Sulon, Joseph ULiege et al

in Veterinary Journal (2003), 165(3), 307-313

Inoculation with Actinomyces pyogenes and administration of prostaglandin (PG) F-2alpha were used to induce late embryonic mortality (LEM) in heifers (n = 8) on Days 30-38 of pregnancy in order to compare ... [more ▼]

Inoculation with Actinomyces pyogenes and administration of prostaglandin (PG) F-2alpha were used to induce late embryonic mortality (LEM) in heifers (n = 8) on Days 30-38 of pregnancy in order to compare the profile for bovine pregnancy associated glycoprotein 1 (PAG1), progesterone and 15-keto-13,14-dihydro-PGF(2alpha) (PGFM). Two pregnant heifers were used as controls. Inoculation into the uterine body caused LEM, as established by ultrasonography in each heifer within 24 h of treatment. When the inoculum was injected into the first part of the cervix, LEM occurred in one of two heifers (Heifer A) between 48 and 72 h after treatment. Similarly, PGF(2alpha) treatment caused LEM in three of four heifers. In six of eight heifers, PAG1 started to decrease steadily when it was accompanied by the subsequent death of the embryo. Inoculation through the cervix caused luteolysis in three of four heifers within 6-10 days after induction. After induction of LEM, PGFM concentrations showed a two to 3.8 fold increase in three of four heifers during the following six days, and from that time changed within normal ranges. The results of this study indicate that a PAG1 assay may provide an alternative method to ultrasonography for determining LEM in the cow. [less ▲]

Detailed reference viewed: 22 (0 ULiège)
Full Text
See detail“Beauté, mon beau souci”. Propos sur une biographie de l’éditeur belge Edmond Deman
Durand, Pascal ULiege

in Epilogue, Bulletin canadien pour l’histoire du livre et l’histoire des bibliothèques et des archives (2003), 13

Detailed reference viewed: 46 (8 ULiège)
Full Text
Peer Reviewed
See detail« Comment servir le souverain ». A propos d’un traité pseudo-platonicien inédit
Bauden, Frédéric ULiege; Ghersetti, Antonella

in Quaderni di Studi Arabi (2003), 20-21

Detailed reference viewed: 42 (4 ULiège)
Full Text
Peer Reviewed
See detailDiscriminative stimulus effects of ethanol with a conditioned taste aversion procedure: lack of acetaldehyde substitution
Quertemont, Etienne ULiege

in Behavioural Pharmacology (2003), 14(4), 343-350

Acetaldehyde has been suggested to mediate a number of the pharmacological and behavioural effects of ethanol. Recently, several studies investigated the role of acetaldehyde in the subjective effects of ... [more ▼]

Acetaldehyde has been suggested to mediate a number of the pharmacological and behavioural effects of ethanol. Recently, several studies investigated the role of acetaldehyde in the subjective effects of ethanol, but obtained conflicting results. With the discriminative taste aversion (DTA) procedure, high acetaldehyde doses were shown to substitute for the discriminative stimulus effects of ethanol. In contrast, the operant drug discrimination protocol failed to show any substitution effect of acetaldehyde. Several methodological differences between the two procedures could explain these discrepancies, and particularly the absence of an individual discrimination criterion in the DTA procedure. In the present study, the DTA procedure was adapted to introduce such a criterion. In addition, the effects of acetaldehyde were compared with those of other drugs, for which the substitution effects for ethanol are well known. Rats were trained to discriminate 1.0 g/kg ethanol from saline in a DTA protocol. When the rats met the criterion of ethanol discrimination, various doses of several drugs were tested for their ethanol stimulus substitution effects: ethanol, acetaldehyde, dizocilpine, diazepam and nicotine. The results showed a clear dose-dependent discrimination of ethanol stimulus effects. In addition, dizocilpine fully substituted for ethanol, while diazepam only partially substituted. In contrast, both acetaldehyde and nicotine failed to substitute for ethanol. These results show that acetaldehyde is not significantly involved in the subjective and discriminative stimulus effects of ethanol. Acetaldehyde up to toxic doses did not substitute for the ethanol discriminative stimulus in the DTA protocol, when non-specific effects were carefully controlled. [less ▲]

Detailed reference viewed: 32 (3 ULiège)
Full Text
Peer Reviewed
See detailPredictive factors in locally advanced rectal cancer treated with preoperative hyperfractionated and accelerated radiotherapy.
Bouzourene, H; Bosman, F; Matter, M et al

in Human Pathology (2003), 34(6), 541-548

This study examines the prognostic significance of pathologic factors in patients with primary locally advanced rectal cancer treated prospectively with preoperative radiotherapy. From 1992 to 1998, 104 ... [more ▼]

This study examines the prognostic significance of pathologic factors in patients with primary locally advanced rectal cancer treated prospectively with preoperative radiotherapy. From 1992 to 1998, 104 patients with rectal cancer of grades T3 or T4 and any N underwent preoperative radiotherapy followed by surgical resection. Survival curves were estimated according to the Kaplan-Meier method. Correlation of outcome with clinicopathologic variables (pathologic tumor and lymph node staging, histology, radial resection margin [RRM], clearance, vessel involvement, and tumor regression grade [TRG], quantitated in 5 grades) was evaluated using the Cox proportional hazards model. None of the patients achieved a histologically confirmed complete pathologic response, but 79% of the patients showed partial tumor regression (TRG2–4) and 21% did not show any tumor regression (TRG5). Among the tumors, 22% were of a mucinous type. The RRM was free of tumor in 76% of the surgical specimens. The median clearance was 2 mm. Vascular invasion was present in 37 cases (36%). In the univariate analysis, lymph node metastases, absence of tumor regression, positive RRM, and vascular invasion were correlated with adverse overall survival and diseasefree survival; absence of tumor regression, positive RRM, and clearance <2 mm were correlated with local recurrences; and advanced pT stage was correlated only with disease-free survival. However, in the multivariate analysis, only lymph node metastases and RRM were independent prognostic factors for overall survival and disease-free survival, and clearance <2 mm was an independent prognostic factor for local control. Pathologic parameters remain strong determinants of local recurrence and survival in locally advanced rectal cancer, treated preoperatively with hyperfractionated and accelerated radiotherapy. We show that patients with advanced pT, positive lymph nodes, vascular invasion, positive RRM, clearance <2 mm, or absence of tumor regression are known to have poor clinical outcome. HUM PATHOL 34:541-548. © 2003 Elsevier Inc. All rights reserved. Abbreviations: , computed tomography; DFS, disease-free survival; HART, hyperfractionated accelerated radiotherapy; OS, overall survival; RRM, radial resection margin; TRG, tumor regression grade. [less ▲]

Detailed reference viewed: 30 (4 ULiège)
Full Text
Peer Reviewed
See detailIn vitro stability and immunoreactivity of the native and recombinant plant food 2S albumins Ber e 1 and SFA-8
Murtagh, M.; Archer, D.; Dumoulin, Mireille ULiege et al

in Clinical & Experimental Allergy : Journal of the British Society for Allergy & Clinical Immunology (2003), 8

Background The ability of an intact protein to reach the circulatory system may be a prerequisite to allergenicity and many allergens, particularly those from plant foods, have been found to be ... [more ▼]

Background The ability of an intact protein to reach the circulatory system may be a prerequisite to allergenicity and many allergens, particularly those from plant foods, have been found to be consistently more resistant to digestion by pepsin than other proteins. Objective This study assessed the pepsinolytic stability of native 2S albumins from Brazil nut and sunflower seed and their recombinant versions produced in Pichia pastoris. The physicochemical stability of native and recombinant Brazil nut 2S albumins and recombinant sunflower seed 2S albumin was also assessed. The immunoreactivity of native Brazil nut 2S albumin and recombinant 2S albumins was compared using serum from patients allergic to Brazil nuts and animals immunized with native 2S albumins. Methods Digestibility was measured in simulated gastric fluid followed by SDS-PAGE. Circular dichroism spectra were used to analyse unfolding, as proteins were denatured by temperature, pH and guanidinium chloride. Immunoreactivity was assessed by immunoblot, RAST and ELISA. Results Brazil nut 2S albumin was significantly more resistant to proteolytic digestion than other Brazil nut proteins. It was also resistant to thermally and chemically induced denaturation. Equally high resistance to proteolytic digestion was observed with sunflower seed 2S albumin. The recombinant albumins mirrored their native counterparts in stability and immunoreactivity. Conclusion The important food allergen Brazil nut 2S albumin is as stable to digestion as is sunflower seed 2S albumin, whose allergenicity has yet to be determined. The 2S albumins and their recombinant counterparts could not be easily denatured by physicochemical treatments. The results suggest that 2S albumin is the only Brazil nut protein to reach the gut immune system intact. The production of properly folded recombinant proteins will facilitate mechanistic studies as well as diagnostic testing and antigen-based therapies. [less ▲]

Detailed reference viewed: 35 (1 ULiège)
Full Text
See detailIntroduction
Jacquemain, Marc ULiege; Verjans, Pierre ULiege

in Fédéralisme - Régionalisme (2003), 2002-2003(n° spécial « Mobilité et identités dans l’Eurégio Meuse-Rhin »), 3-11

Detailed reference viewed: 27 (8 ULiège)
Full Text
Peer Reviewed
See detailBildegedende diagnostik des gehirns beim alternden hund
Van Bree, H.; Gielen, I.; Peremans, K. et al

in Der Prattische Tierazt (2003)

Detailed reference viewed: 9 (0 ULiège)
Full Text
Peer Reviewed
See detailLipid And Oxylipin Profiles During Aging And Sprout Development In Potato Tubers (Solanum Tuberosum L.)
Fauconnier, Marie-Laure ULiege; Welti, R.; Blee, E. et al

in Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids (2003), 1633(2),

Detailed reference viewed: 18 (6 ULiège)
Full Text
Peer Reviewed
See detailRecognising the usual orientation of one's own face : the role of asymmetrically located details
Brédart, Serge ULiege

in Perception (2003), 32(7), 805-811

Our ability to recognise the usual horizontal orientation Of Our own face (mirror orientation) as compared with another very familiar face (normal orientation) was examined in experiment 1. Participants ... [more ▼]

Our ability to recognise the usual horizontal orientation Of Our own face (mirror orientation) as compared with another very familiar face (normal orientation) was examined in experiment 1. Participants did not use the same kind of information in determining the orientation of their own face as in determining the orientation of the other familiar face. The proportion of participants who reported having based their judgment on the location of an asymmetric feature (eg a mole) was higher when determining the orientation of their own face than when determining that of the other familiar face. In experiment 2, participants were presented with pairs of manipulated images of their own face and of another familiar face showing conflicting asymmetric features and configural information. Each pair consisted of one picture showing asymmetric features of a given face in a mirror-reversed position, while the facial configuration was left unchanged; and one picture in which the location of the asymmetric features was left unchanged, while the facial configuration was mirror-reversed. As expected from the hypothesis that asymmetric local features are more frequently used for the judgment of one's own face, participants chose the picture showing mirror-reversed asymmetric features when determining the usual orientation of their own face significantly more often than they chose the picture showing normally oriented asymmetric features when determining the orientation of the other face. These results are explained in terms of competing forward and mirror-reversed representations of one's own face. [less ▲]

Detailed reference viewed: 120 (13 ULiège)
Full Text
See detailUtilisation du tableur Excel pour le remboursement d'un emprunt par une annuité
Henry, Valérie ULiege; Coolen, Annette ULiege

in Mathématique et Pédagogie (2003), 143

Detailed reference viewed: 11 (2 ULiège)
Full Text
Peer Reviewed
See detailLong-term disease-free survival in patients with angioimmunoblastic T-cell lymphoma after high-dose chemotherapy and autologous stem cell transplantation.
Schetelig, Johannes; Fetscher, Sebastian; Reichle, Albrecht et al

in Haematologica (2003), 88(11), 1272-8

BACKGROUND AND OBJECTIVES: Patients with angioimmunoblastic T-cell lymphoma (AIL) have a poor prognosis with conventional treatment. DESIGN AND METHODS: We initiated an EBMT-based survey studying the ... [more ▼]

BACKGROUND AND OBJECTIVES: Patients with angioimmunoblastic T-cell lymphoma (AIL) have a poor prognosis with conventional treatment. DESIGN AND METHODS: We initiated an EBMT-based survey studying the impact of high-dose chemotherapy (HDCT) and autologous hematopoietic stem cell transplantation in patients with AIL. Data on 29 patients, who were transplanted between 1992 and 1998 in 16 transplant centers, were collected on standardized documentation forms. RESULTS: The median age at transplantation was 53 years. HDCT was given as part of 1st-line therapy (N=14; 48%) or 2nd/3rd-line therapy (N=15; 52%). Regimens for the mobilization of peripheral blood stem cells (PBSC) included VIPE (N=7; 26%), DexaBEAM (N=6; 22%), CHOP-like regimens (N=6; 22%), other regimens (N=5; 19%) or alternatively growth factor alone (N=3; 11%). The median yield of PBSC was 3.8x106 CD34+cells/kg. Two patients received autologous bone marrow. The HDCT consisted of BEAM-type regimens in 16 patients, ICE-type regimens in 7, and other regimens in 6 patients. There was one treatment-related death. The rate of complete remissions increased from 45% before HDCT to 76% after HDCT. As of January 2003, after a median observation time of living patients of 5 years (range 2.5 to 10 years), 14 patients have died (13 from progressive disease), and 15 patients are alive. The probability of 5-year overall and event-free survival was 44% (95% CI, 22% to 66%) and 37% (95% CI, 17% to 57%), respectively. Long-term disease-free survival was observed in patients transplanted during 1st-line treatment as well as in the context of 2nd/3rd-line therapy. INTERPRETATION AND CONCLUSIONS: There is evidence that AIL is susceptible to high-dose chemotherapy. HDCT and autologous stem cell transplantation should be considered in selected patients with AIL. [less ▲]

Detailed reference viewed: 129 (0 ULiège)
Full Text
Peer Reviewed
See detailA New Wor(l)d Order: Language in the Fiction of the New Caribbean Diaspora
Ledent, Bénédicte ULiege

in Revista Alicantina de Estudios Ingleses (2003), 16

Language has always been a major issue for post-colonial writers, being at once an instrument used by the colonial power and one of the prime avenues of resistance to this oppression. For displaced West ... [more ▼]

Language has always been a major issue for post-colonial writers, being at once an instrument used by the colonial power and one of the prime avenues of resistance to this oppression. For displaced West Indian writers in particular, English has been a significant tool for self-assertion, all the more ambiguous because it is their "mother tongue" while being the tongue of their ancestors' masters as well. This paper analyses how the younger novelists of the Caribbean diaspora use and transform the English language in their search for a new diasporic, cross-cultural identity. Robert Antoni, Michelle Cliff, Fred D'Aguiar, David Dabydeen, M. Nourbese Philip and Caryl Phillips will be among the writers mentioned in this paper. While some of them resort to non-standard linguistic forms and thereby deal head on with the tension between local languages and the need for international communication, others have had a more oblique approach to linguistic change, one that involves not so much lexis as tone and rhythm and often operates by rehabilitating silenced voices from the past. I will attempt to demonstrate how these writers have turned speech into a site of creolization expressive of what Caryl Phillips has called" A New World Order". [less ▲]

Detailed reference viewed: 441 (16 ULiège)
Full Text
Peer Reviewed
See detailRecombinant human erythropoietin therapy is very effective after an autologous peripheral blood stem cell transplant when started soon after engraftment.
Baron, Frédéric ULiege; Frere, Pascale ULiege; Fillet, Georges ULiege et al

in Clinical Cancer Research : An Official Journal of the American Association for Cancer Research (2003), 9(15), 5566-72

PURPOSE: Previous trials of recombinant human erythropoietin (rHuEpo) therapy after autologous hematopoietic stem cell transplantation have administered very high doses of i.v. rHuEpo starting on day 1 ... [more ▼]

PURPOSE: Previous trials of recombinant human erythropoietin (rHuEpo) therapy after autologous hematopoietic stem cell transplantation have administered very high doses of i.v. rHuEpo starting on day 1 and continuing for 1-2 months until erythroid engraftment and have shown no benefit of rHuEpo therapy. We sought to establish a more effective use of rHuEpo in this setting. EXPERIMENTAL DESIGN: In this report, we show in a first cohort of 45 lymphoma or myeloma patients undergoing peripheral blood stem cell transplant (control group) that endogenous erythropoietin levels are high for the degree of anemia during the first 3 weeks after transplant but become adequate or slightly decreased thereafter. We thus enrolled 41 consecutive similar patients in a trial of rHuEpo therapy at a dose of 500 units/kg/week started on day 30 after the transplant. RESULTS: The 12-week probability of achieving hemoglobin (Hb) levels of 13 g/dl was 87% in rHuEpo-treated patients versus 14% in controls (P = 0.0001). Mean Hb levels were significantly higher in the rHuEpo group than in the control group from day 42 through day 150 after transplant (Ps of <0.05 to <0.001). Two of 41 patients in the rHuEpo group versus 12 of 45 patients in the control group had Hb levels of <9 g/dl between day 42 and day 100 after the transplant (P = 0.0078). CONCLUSIONS: Anemia after autologous peripheral blood stem cell transplant is exquisitely sensitive to rHuEpo when therapy is started soon after engraftment. This is the first convincing report showing that rHuEpo is effective in this setting. Our data set the stage for a more rational use of rHuEpo after autologous hematopoietic stem cell transplantation and should renew interest in erythropoietin therapy in this setting. Prospective, randomized trials should investigate the impact of rHuEpo therapy on transfusion requirements and quality of life. [less ▲]

Detailed reference viewed: 34 (0 ULiège)
Full Text
Peer Reviewed
See detailImpact Of The Horizontal Movements Of A Sprayer Boom On The Longitudinal Spray Distribution In Field Conditions
Ooms, David ULiege; Ruter, R.; Lebeau, Frédéric ULiege et al

in Crop Protection (2003), 22(6),

Detailed reference viewed: 39 (12 ULiège)
Full Text
Peer Reviewed
See detailDie Medien der Germanistik und die Nöte des Nachwuchses
Pontzen, Alexandra ULiege

in Jahrbuch der Deutschen Schillergesellschaft (2003), XLVII

Detailed reference viewed: 16 (0 ULiège)
Full Text
Peer Reviewed
See detailComment j'explore ... la cinetique glycemique des patients diabetiques par monitoring continu du glucose interstitiel.
Radermecker, Régis ULiege; Magis, Delphine ULiege; Selam, J. L. et al

in Revue Médicale de Liège (2003), 58(3), 164-7

The improvement of diabetic patients' glycaemic status requires an increase of fingerstick blood glucose measurements. Among the possibilities available to assess diabetes' control, we will consider new ... [more ▼]

The improvement of diabetic patients' glycaemic status requires an increase of fingerstick blood glucose measurements. Among the possibilities available to assess diabetes' control, we will consider new systems of continuous interstitial glucose monitoring. After a brief description of the devices presently commercialized, we will discuss their indications and their limitations, as well as their future prospects in a possible "closed loop" insulin delivery according to blood glucose level. [less ▲]

Detailed reference viewed: 123 (16 ULiège)
Full Text
Peer Reviewed
See detailSelection of the most efficient wavelength bands for 'Jonagold' apple sorting
Kleynen, O.; Leemans, Vincent ULiege; Destain, Marie-France ULiege

in Postharvest Biology & Technology (2003), 30(3), 221-232

This paper presents a method based on quadratic discriminant analysis to select the best filters for detecting a wide range of defects in 'Jonagold' apple fruit using a multi-spectral vision system ... [more ▼]

This paper presents a method based on quadratic discriminant analysis to select the best filters for detecting a wide range of defects in 'Jonagold' apple fruit using a multi-spectral vision system. Reflectance spectra of damaged and sound tissue were recorded using a visible/NIR spectrometer. Analysed defects consisted of scald, hail damage (with and without skin perforation), limb rubs, russets, scab tissue, frost damage, rot, visible flesh damage and recent bruises. Camera filter effects were approximated by summing the reflectances of all the wavelengths within the filter bandwidth. Combinations of three and four filters were tested and evaluated for discriminating damaged tissues from healthy ones. If a three-filter combination appeared sufficient to detect most of the damaged tissue, a four-filter combination should be considered for the complete sorting automation of this bicolour apple variety. A fourth filter was necessary to quantify the ratio between the blush and ground colours. Regarding recent bruise defects which represented the major difficulty, an image segmentation algorithm based on local contrast variations can enhance their detection. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

Detailed reference viewed: 76 (6 ULiège)
Full Text
Peer Reviewed
See detailArterial embolization as a treatment of chronic edema following free cutaneous flap transfer to the lower limbs.
Tchuisse, Charlemagne Noukoua; Barah, Ali; NCHIMI LONGANG, Alain ULiege et al

in Cardiovascular & Interventional Radiology (2003), 26(3), 316-8

Persisting chronic edema following postoperative free flap transfer is a common complication. We report 3 cases of successful treatment by selective arterial embolization of the feeding arterial branches ... [more ▼]

Persisting chronic edema following postoperative free flap transfer is a common complication. We report 3 cases of successful treatment by selective arterial embolization of the feeding arterial branches without side effect. One session embolization is advocated as a first line treatment of this condition. [less ▲]

Detailed reference viewed: 12 (2 ULiège)
Full Text
Peer Reviewed
See detailAn approach for dividing models of biological reaction networks into functional units
Ederer, Michael; Sauter, Thomas; Bullinger, Eric ULiege et al

in Simulation: Trans. Society for Modeling and Simulation International (2003), 79(12), 703-716

Biological reaction networks consist of many substances and reactions between them. Like many other biological systems, they have a modular structure. Therefore, a division of a biological reaction ... [more ▼]

Biological reaction networks consist of many substances and reactions between them. Like many other biological systems, they have a modular structure. Therefore, a division of a biological reaction network into smaller units highly facilitates its investigation. The authors propose an algorithm to divide an ordinary differential equation (ODE) model of a biological reaction network hierarchically into functional units. For every compound, an activity function dependent on concentration or concentration change rate is defined. After performing suitable simulations, distances between the compounds are computed by comparing the activities along the trajectories of the simulation. The distance information is used to generate a dendrogram revealing the internal structure of the reaction network. The algorithm identifies functional units in two models of different networks: catabolite repression in Escherichia coli and epidermal growth factor (EGF) signal transduction in mammalian cells. [less ▲]

Detailed reference viewed: 17 (2 ULiège)
Full Text
Peer Reviewed
See detailDiagnostic et suivi de la gravidité chez le zébu par échographie
Pitala, W.; Boly, H.; Zongo, M. et al

in Revue d'Elévage et de Médecine Vétérinaire des Pays Tropicaux (2003), 56(3-4), 171-176

Des diagnostics de gravidité ont été réalisés chez 64 femelles zébus de races Peuhl et Goudali (Bos indicus) aux 28è et 40è jours postinsémination à l'aide d'un échographe muni d'une sonde linéaire de 6 ... [more ▼]

Des diagnostics de gravidité ont été réalisés chez 64 femelles zébus de races Peuhl et Goudali (Bos indicus) aux 28è et 40è jours postinsémination à l'aide d'un échographe muni d'une sonde linéaire de 6 MHz. Au 28è jour, l'exactitude globale a été de 92,2 p. 100, avec une exactitude de 92,6 p. 100 et 91,9 p. 100 respectivement pour les diagnostics positif et négatif. Au 40è jour, l'exactitude globale a été de 98,4 p. 100, avec une exactitude de 100 p. 100 et 97,3 p. 100 respectivement pour les diagnostics positif et négatif. Les fiabilités ont varié de 89,2 p. 100 (fiabilité du diagnostic de gravidité positif au 28è jour) à 100 p. 100 (fiabilité du diagnostic de gravidité négatif au 40è jour). Par ailleurs, la croissance foetale a été suivie chez 16 femelles gravides du 45è au 120è jour postinsémination. Les principales mensurations foetales réalisées ont été les diamètres du crâne et du tronc. Au 45è jour de la gravidité, les diamètres du crâne et du tronc ont été respectivement de 1,8 ± 0,1 cm et 1,4 ± 0,3 cm. Au 120è jour, ces valeurs ont été de 6,5 ± 0,6 cm et 5,8 ± 0,5 cm. A partir du 120è jour, l'utérus a pris une position très profonde, ne permettant plus la visualisation du foetus en croissance. [less ▲]

Detailed reference viewed: 11 (0 ULiège)
Full Text
Peer Reviewed
See detailGraulichite-(Ce), a new arsenate mineral from the Stavelot Massif, Belgium
Hatert, Frédéric ULiege; Pasero, Marco; Fransolet, André-Mathieu ULiege et al

in European Journal of Mineralogy (2003), 15(4, JUL-AUG), 733-739

Graulichite-(Ce), ideally CeFe33+(AsO4)(2)(OH)(6), is a new mineral species from Hourt, Stavelot Massif, Belgium. It occurs in the most altered parts of a Devillian quartzite (Lower to Middle Cambrian ... [more ▼]

Graulichite-(Ce), ideally CeFe33+(AsO4)(2)(OH)(6), is a new mineral species from Hourt, Stavelot Massif, Belgium. It occurs in the most altered parts of a Devillian quartzite (Lower to Middle Cambrian), in close association with arsenopyrite, scorodite, mimetite, pharmacosiderite, and goethite. Graulichite-(Ce) forms 80 to 150 mum spherical aggregates of rhombohedral crystals, 50 to 80 mum length, which show the forms {10 (1) over bar2} and {10 (11) over bar}. The mineral is transparent and exhibits a light-green to brownish colour, with a resinous lustre. It is non-fluorescent and shows an irregular fracture, without any perceptible cleavage. The calculated density is 4.42 g/cm(3). Graulichite-(Ce) is uniaxial negative, with a mean refractive index close to 1.97(1) (lambda=590 nm), pleochroic from light green to yellowish. Electron microprobe analyses gave As2O5 31.20, P2O5 0.03, SO3 0.06, SiO2 0.03, Al2O3 3.09, Fe2O3 30.65, SrO 0.24, PbO 0.07, BaO 3.95, CaO 0.03, La2O3 2.26, Ce2O3 15.73, Nd2O3 2.08, H2O (calc.) 8.37, total 97.79 wt. %. The resulting empirical formula, calculated on the basis of 6 cations, is (Ce0.67Ba0.18La0.10Nd0.09Sr0.02)(Sigma1.06) (Fe2.683+Al0.42)(Sigma3.10)[(As(1.89)S(.001)square(0.10))(Sigma2.00)O-8][(OH)(5.57)(H2O)(0.43)](Sigma6.00). The single-crystal unit-cell parameters are a=7.288(2) and c=16.812(9) Angstrom, space group R (3) over barm. The seven strongest lines in the X-ray powder-diffraction pattern [d(in Angstrom)(I)(hkil)] are: 3.052(100)(11 (2) over bar3), 3.636(40)(11 (2) over bar0), 2.239(35)(10 (1) over bar7), 1.817(35)(22 (4) over bar0), 2.792(30)(0006), 5.906(25)(10 (1) over bar1), 1.968(25)(30 (3) over bar3). Graulichite-(Ce) is the iron analogue of arsenoflorencite-(Ce), and belongs to the crandallite mineral group, with the alunite-type structure. The crystal structure of graulichite-(Ce) has been refined, based on single-crystal X-ray diffraction data, to R=0.048. [less ▲]

Detailed reference viewed: 42 (3 ULiège)
Full Text
Peer Reviewed
See detailShortened irradiation scheme, continuous infusion of 5-fluorouracil and fractionation of mitomycin C in locally advanced anal carcinomas. Results of a phase II study of the European Organization for Research and Treatment of Cancer. Radiotherapy and Gastrointestinal Cooperative Groups
Bosset, J. F.; Roelofsen, F.; Morgan, D. A. L. et al

in European Journal of Cancer (2003), 39

Abstract The European Organization for Research and Treatment of Cancer (EORTC) 22861 randomised trial established that combined radiochemotherapy is the standard treatment for locally advanced anal ... [more ▼]

Abstract The European Organization for Research and Treatment of Cancer (EORTC) 22861 randomised trial established that combined radiochemotherapy is the standard treatment for locally advanced anal cancer. This EORTC phase II study (#22953) tests the feasibility of reducing the gap between sequences to 2 weeks, to deliver Mitomycin C (MMC) in each radiotherapy sequence and 5-FU continuously during the treatment. The first sequence consisted of 36 Gy over 4 weeks. 5-FU 200 mg/m2/days 1–26, MMC 10 mg/m2/day 1 gap 16 days. Then a second sequence of 23.4 Gy over 17 days, 5-FU 200 mg/m2/days 1–17 and, MMC 10 mg/m2/day 1 was given. 43 patients with a World Health Organization (WHO) status of 0 (n=27) or 1 (n=16) and with T2-T4, N0-3 tumours were included. Compliance with the planned treatment, doses and duration was 93%. The complete response rate was 90.7%. Grade 3 toxicities of 28, 12 and 2% were observed for skin, diarrhoea and haematological toxicities, respectively. The 3-year estimated rates for trials 22861 and 22953 are: 68 and 88% for local control; 72 and 81% for colostomy-free interval, 62 and 84% for severe late toxicity-free interval, and 70 and 81% for survival, respectively. The 22953 scheme is feasible and the results are promising. This is now considered as the new standard scheme by the EORTC. [less ▲]

Detailed reference viewed: 62 (3 ULiège)
Full Text
Peer Reviewed
See detailExperimental comparison of cavity sealing ability of five dental adhesive systems after thermocycling
Cao, L.; Geerts, Sabine ULiege; Gueders, Audrey ULiege et al

in Journal of Adhesive Dentistry (2003), 5(2, Summer), 139-144

Purpose: To evaluate the cavity sealing obtained after thermocycling with five adhesive systems in which one all-in-one adhesive was compared to three one-bottle adhesives, and to observe the effect of a ... [more ▼]

Purpose: To evaluate the cavity sealing obtained after thermocycling with five adhesive systems in which one all-in-one adhesive was compared to three one-bottle adhesives, and to observe the effect of a low-charged resin layer added to a one-bottle adhesive. Materials and Methods: Twenty-five recently extracted teeth were randomly allocated to five experimental adhesive systems (n = 5 each): Optibond Solo (OS), Scotchbond 1 (SB1), PQ 1, Prompt-L-Pop (PLP), SB1+Revolution (R). On each tooth, two rectangular cavities at the cementoenamel junction were filled with a microhybrid composite (Z100) and the tested adhesives. Teeth were thermocycled and stained with AgNO3 + vitamin C. Leakage was evaluated on a 6-point (0-5) severity scale and the highest score was selected for each restoration. Results were treated by ordinal logistic regression and considered to be significant at p < 0.05. Results: No significant difference was found between leakage values for enamel and dentin interfaces. Leakage scores never exceeded 2 for OS, SB1 and SB1+R, while they reached a maximum of 5 in 20% of PLP cases. OS was significantly better than the other adhesive systems, which were statistically equivalent. The addition of a flowable composite layer on SB1 did not yield a significant difference, but tended to give better results mainly at the dentin interface. Conclusion: The all-in-one adhesive PLP because of quite variable results, seems less reliable than the one-bottle adhesives, of which OS provides significantly the best results. Addition of a flowable composite on SB1 appears to yield slightly better results. [less ▲]

Detailed reference viewed: 124 (3 ULiège)
Full Text
Peer Reviewed
See detailA low rate of trisomy 21 in twin-pregnancies: A cytogenetics retrospective study of 278 cases
Jamar, Mauricette ULiege; Lemarchal, C.; Koulischer, Lucien ULiege et al

in Genetic Counseling (2003), 14(4), 395-400

Detailed reference viewed: 39 (4 ULiège)
Full Text
Peer Reviewed
See detailILLUSTRATION OF MODERN BENTHIC FORAMINIFERA FROMBERMUDA AND REMARKS ON DISTRIBUTION IN OTHER SUBTROPICAL/TROPICAL AREAS
Javaux, Emmanuelle ULiege; Scott, David

in Palaeontologia Electronica (2003), 6(4), 1-29

A scanning light microscope (SLM) is used to illustrate recent benthic foraminiferal species from surface sediment samples collected in Bermuda subtropical environments. Species illustrated here are the ... [more ▼]

A scanning light microscope (SLM) is used to illustrate recent benthic foraminiferal species from surface sediment samples collected in Bermuda subtropical environments. Species illustrated here are the main foraminiferal species found in Bermuda lagoons, reefs, caves, mangroves, and ponds, but also occur in most subtropical and tropical areas. The SLM permits photography of specimens without coating and gives pictures most similar to specimens that micropaleontologists see under a dissecting reflected light microscope in a petri dish with water, in contrast to images made with scanning electron microscopes. These pictures are the first SLM illustrations of subtropical/tropical species of benthic foraminifera and will be very useful for their identification. Bermuda recent sediment hosts a benthic foraminifera fauna as diverse as in other subtropical and tropical areas, and the general trends of foraminiferal distribution and morphology are similar. Remarks on foraminiferal distribution in Bermuda and other subtropical/tropical areas are also presented. [less ▲]

Detailed reference viewed: 60 (2 ULiège)
Full Text
Peer Reviewed
See detailFracture prevention in postmenopausal women.
Bruyère, Olivier ULiege; Edwards, John; Reginster, Jean-Yves ULiege

in Clinical Evidence (2003), 9

Detailed reference viewed: 30 (10 ULiège)
Full Text
Peer Reviewed
See detailLow T-cell chimerism is not followed by graft rejection after nonmyeloablative stem cell transplantation (NMSCT) with CD34-selected PBSC.
Baron, Frédéric ULiege; Baudoux, Etienne ULiege; Frere, Pascale ULiege et al

in Bone Marrow Transplantation (2003), 32(8), 829-34

We investigate the feasibility of CD34-selected peripheral blood stem cell (PBSC) transplantation followed by pre-emptive CD8-depleted donor lymphocyte infusions (DLI) after a minimal conditioning regimen ... [more ▼]

We investigate the feasibility of CD34-selected peripheral blood stem cell (PBSC) transplantation followed by pre-emptive CD8-depleted donor lymphocyte infusions (DLI) after a minimal conditioning regimen. Six patients with advanced hematological malignancies ineligible for a conventional myeloablative transplant (n=5) or metastatic renal cell carcinoma (n=1), and with an HLA-identical (n=4) or alternative (n=2) donor were included. The nonmyeloablative conditioning regimen consisted in 2 Gy TBI alone (n=4), 2 Gy TBI and fludarabine (RCC patient, n=1) or cyclophosphamide and fludarabine (patient who had previously received 12 Gy TBI, n=1). Post transplant immunosuppression was carried out with cyclosporin (CyA) and mycophenolate mofetil (MMF). Initial engraftment was achieved in all patients. One out of six patients (17%) experienced grade > or =2 acute GVHD only after abrupt cyclosporin discontinuation and alpha interferon therapy for life-threatening tumor progression. T-cell chimerism was 23% (19-30) on day 28, 32% (10-35) on day 100, 78% (49-95) on day 180 and 99.5% (99-100) on day 365. Three out of four patients who had measurable disease before the transplant experienced a complete response. We conclude that CD34-selected NMSCT followed by CD8-depleted DLI is feasible and preserves engraftment and apparently also the graft-versus-leukemia (GVL) effect. Further studies are needed to confirm this encouraging preliminary report. [less ▲]

Detailed reference viewed: 61 (6 ULiège)
Full Text
Peer Reviewed
See detailEffect of rival males on the courtship of paedomorphic and metamorphic Triturus alpestris (Amphibia : Salamandridae)
Denoël, Mathieu ULiege

in Copeia (2003), 2003(3), 618-623

Current theories on the alternative mating tactics suppose that individuals may opt for particular behavioral patterns depending of their morphological status. Facultative paedomorphosis in newts and ... [more ▼]

Current theories on the alternative mating tactics suppose that individuals may opt for particular behavioral patterns depending of their morphological status. Facultative paedomorphosis in newts and salamanders is a suitable process to explore this question because it implies the coexistence of two different morphological morphs differing by the presence of gills and epigamic traits. The aim of this study was to find out whether paedomorphs and metamorphs use similar tactics to attract mates in the presence of a rival and whether there are differences in sexual activity and success between alternative morphs. Sexual interactions in triadic encounters were staged and analyzed in a standardized experimental design. The two kinds of males did not differ in terms of sexual activity, spermatophore deposition or female responsiveness. Both rival paedomorphic and metamorphic males exhibited sexual interference, but in most encounters, intruders just disturbed the courting pair. Sperm transfer success was lower in triadic encounters than in dyadic encounters. These results illustrate that intermorph breeding also occurs in the presence of competitors but that the success rate of the newts is considerably decreased in such competitive situations. Moreover, newts do not use alternative reproductive tactics depending on their status (i.e., paedomorph or metamorph). [less ▲]

Detailed reference viewed: 142 (9 ULiège)
Full Text
Peer Reviewed
See detailNudging epidermal field cancerogenesis by imiquimod.
Uhoda, Isabelle; Quatresooz, Pascale ULiege; Pierard, Claudine ULiege et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (2003), 206(4), 357-60

BACKGROUND: The coexistence of malignancies close to each other on the skin has been occasionally reported. The concept of field cancerogenesis applies to such cases. Given the purported mechanism of ... [more ▼]

BACKGROUND: The coexistence of malignancies close to each other on the skin has been occasionally reported. The concept of field cancerogenesis applies to such cases. Given the purported mechanism of action of imiquimod, it should not be surprising that this treatment could inhibit epidermal field cancerogenesis. AIM: To assess the effect of imiquimod applied twice weekly on incipient bowenoid changes disclosed in the vicinity of basal cell carcinomas. MATERIALS AND METHOD: Biopsies were taken before treatment and after 4-6 weeks and 12 weeks of imiquimod treatment. RESULTS: Large atypical bowenoid keratinocytes and dyskeratotic cells were cleared in time while factor-XIIIa-positive dermal dendrocytes appeared boosted and admixed with a brisk lymphocytic infiltration. CONCLUSION: Epidermal field cancerogenesis appears to be controlled by imiquimod. Dermal dendrocytes might play a pivotal role in this regression phenomenon. [less ▲]

Detailed reference viewed: 25 (2 ULiège)
Full Text
See detaille monument à Léopold Ier: aux origines de l'urbanisation de Laeken
Houbart, Claudine ULiege

in Notre Comté. Annales du cercle d'histoire, d'archéologie et de folklore du comté de Jette et de sa région (2003), XXX

Detailed reference viewed: 44 (4 ULiège)
Full Text
Peer Reviewed
See detailLa sentence arbitrale
Caprasse, Olivier ULiege

in Actualités du Droit (2003), 3

Detailed reference viewed: 20 (1 ULiège)
Full Text
Peer Reviewed
See detailCatecholamine and HPA axis dysfunction in depression : relationship with suicidal behavior
Pitchot, William ULiege; Reggers, Jean ULiege; Pinto, Emmanuel ULiege et al

in Neuropsychobiology (2003), 47(3), 152-157

A large body of evidence suggests a potential role for catecholaminergic function as a possible biological factor in the control of suicidal behavior. Recently, we have used a neuroendocrine strategy to ... [more ▼]

A large body of evidence suggests a potential role for catecholaminergic function as a possible biological factor in the control of suicidal behavior. Recently, we have used a neuroendocrine strategy to study dopaminergic and noradrenergic activities in depressed suicide attempters. However, some problems are associated with the use of growth hormone (GH) response to catecholaminergic challenge, because GH release could be decreased by a direct effect of corticosteroids at the pituitary level. Therefore, the purpose of the present study was to assess GH response to both apornorphine, a dopaminergic agonist, and clonidine, an alpha2-adrenergic agonist, according to the dexamethasone suppression test (DST) status in a sample of 20 major depressed inpatients with a history of suicide attempt compared with nonattempters. Our results tended to show that hypercortisolemia as assessed by post-DST cortisol values did not inhibit GH response to apornorphine or clonidine, suggesting that hypothalamo-pituitary-adrenal axis overactivity does not explain the impaired GH response to apornorphine in major depressed patients with a history of suicide attempt. [less ▲]

Detailed reference viewed: 33 (1 ULiège)
Full Text
Peer Reviewed
See detailLes teignes du cuir chevelu d'ici et d'ailleurs. Quand la prévention est à géographie variable.
Arrese Estrada, Jorge ULiege; Pierard, Claudine ULiege; Pierard, Gérald ULiege

in Revue Médicale de Liège (2003), 58(6), 388-91

Few diseases exhibit such regional variability in their epidemiology, even in an area as limited as Belgium, as tinea capitis. Thus, anthropophilic tinea capitis is highly predominant in areas where new ... [more ▼]

Few diseases exhibit such regional variability in their epidemiology, even in an area as limited as Belgium, as tinea capitis. Thus, anthropophilic tinea capitis is highly predominant in areas where new immigrants from Black Africa and North Africa have settled. By contrast, zoophilic tinea capitis is found largely in areas where the cat population is infected. Kerion often affects professions in which contact with infected livestock is involved. Prevention of tinea capitis thus has distinct regional features. Treatment, on the other hand, has a universal basis. [less ▲]

Detailed reference viewed: 129 (8 ULiège)
Full Text
Peer Reviewed
See detailEarly detection of relapse by whole-body positron emission tomography in the follow-up of patients with Hodgkin's disease.
Jerusalem, Guy ULiege; Beguin, Yves ULiege; Fassotte, Marie-France ULiege et al

in Annals of Oncology (2003), 14(1), 123-30

BACKGROUND: Relapse after treatment of Hodgkin's disease (HD) is usually identified as a result of the investigation of symptoms. We undertook this study to examine the value of whole-body positron ... [more ▼]

BACKGROUND: Relapse after treatment of Hodgkin's disease (HD) is usually identified as a result of the investigation of symptoms. We undertook this study to examine the value of whole-body positron emission tomography (PET) for the detection of preclinical relapse. PATIENTS AND METHODS: Thirty-six patients underwent 2-[fluorine-18]fluoro-2-deoxy-D-glucose ((18)F-FDG) PET at the end of treatment and than every 4-6 months for 2-3 years after the end of polychemotherapy and/or radiotherapy. In those cases of abnormal (18)F-FDG accumulation a confirmatory study was performed 4-6 weeks later. RESULTS: One patient had residual tumor and four patients relapsed during a follow-up of 5-24 months. All five events were correctly identified early by (18)F-FDG PET. Residual tumor or relapse was never first diagnosed based on clinical examination, laboratory findings or computed tomography (CT) studies. Two patients presented B symptoms and the three others were asymptomatic at the time of residual disease or relapse. Confirmation of residual disease or relapse was obtained by biopsy in four patients 1, 1, 5 and 9 months after PET and by unequivocal clinical symptoms and CT studies in one patient 3 months after PET. False-positive (18)F-FDG PET studies incorrectly suggested possible relapse in six other patients, but the confirmatory PET was always negative. Our study also provides important information about physiological (18)F-FDG uptake in the thymus. CONCLUSIONS: Our data suggest the potential of (18)F-FDG PET to detect preclinical relapse in patients with HD. This could help identify patients requiring salvage chemotherapy at the time of minimal disease rather than at the time of clinically overt relapse. Further studies are warranted to determine the impact of PET on treatment management and outcome. In fact, the aim of follow-up procedures is not only to detect preclinical relapse but mainly to obtain better results by starting salvage treatment earlier. A cost-benefit analysis will also be necessary before (18)F-FDG PET can be used routinely in the follow-up of patients with HD. [less ▲]

Detailed reference viewed: 60 (3 ULiège)
Full Text
Peer Reviewed
See detailOnce-weekly epoetin beta is highly effective in treating anaemic patients with lymphoproliferative malignancy and defective endogenous erythropoietin production.
Cazzola, Mario; Beguin, Yves ULiege; Kloczko, Janusz et al

in British Journal of Haematology (2003), 122(3), 386-93

Epoetin beta, three-times weekly (t.i.w.), is effective in reversing anaemia in lymphoproliferative disorders. The current study investigated whether an epoetin beta dose of 30,000 IU given subcutaneously ... [more ▼]

Epoetin beta, three-times weekly (t.i.w.), is effective in reversing anaemia in lymphoproliferative disorders. The current study investigated whether an epoetin beta dose of 30,000 IU given subcutaneously once weekly (q.w.) was at least as effective as 10,000 t.i.w. administration in anaemic patients with lymphoproliferative malignancy and defective endogenous erythropoietin (Epo) production. Overall, 241 anaemic patients with multiple myeloma, low-grade non-Hodgkin's lymphoma or chronic lymphocytic leukaemia, all with serum Epo values </= 100 mU/ml, were randomized to receive the q.w. (n = 119) or t.i.w. (n = 122) regimen for 16 weeks. The primary efficacy criterion, i.e. the time-adjusted area under the haemoglobin-time curve from weeks 5-16, was comparable between the q.w. and t.i.w. groups [difference = - 0.20 g/dl (90% confidence interval - 0.52-0.11)]. Moreover, response rates were high and similar in both arms (72%vs 75%, q.w. and t.i.w. groups respectively). Baseline serum Epo was predictive of response: the lower serum Epo, the higher the likelihood of response (P = 0.002). Thus, epoetin beta administered q.w. is an effective and convenient treatment for anaemia in patients with lymphoproliferative disorders. Tailoring this treatment modality to subjects with defective endogenous Epo production represents a rational use of epoetin from both a medical and a community perspective. [less ▲]

Detailed reference viewed: 37 (0 ULiège)
Full Text
See detailHydrodynamique et morphologie d'une bactérie filamenteuse dans un fermenteur à cuve agitée
Groslambert, Sylvie ULiege; Blacher, Silvia ULiege; Crine, Michel ULiege

in Tribune de l'Eau (La) (2003), 56(622), 58-64

Afin d'étudier l'influence de l'hydrodynamique sur une bactérie filamenteuse, Actinomadura R39, nous l'avons cultivée dans un fermenteur de laboratoire de 5 litres à cuve agitée en faisant varier les ... [more ▼]

Afin d'étudier l'influence de l'hydrodynamique sur une bactérie filamenteuse, Actinomadura R39, nous l'avons cultivée dans un fermenteur de laboratoire de 5 litres à cuve agitée en faisant varier les conditions d'agitation. Les variables sont la vitesse de rotation et le type de mobile utilisé: turbines Rushton ou Intermig. Les deux mobiles se distinguent par leur géométrie et par les schémas d'écoulement qu'ils induisent dans la cuve. L'influence de l'hydrodynamique sur Actinomadura R39 est quantifiée par l'évolution de sa morphologie. Cette dernière est estimée par analyse d'images sur des échantillons prélevés lors des cultures. Parallèlement, nous avons caractérisé l'hydrodynamique du fermenteur dans un milieu artificiel reproduisant la rhéologie des fermentations en mesurant la puissance dissipée et en effectuant des essais de traceurs. Ces derniers sont utilisés pour la modélisation du fermenteur par un modèle compartimenté et le calcul du temps de mélange. Nous avons pu ainsi mettre en relation les modifications de la morphologie et des grandeurs caractérisant les écoulements dans le fermenteur. L'existence de corrélations entre les paramètres du modèle et la morphologie a également permis une validation de la signification physique de ce modèle. [less ▲]

Detailed reference viewed: 35 (1 ULiège)
Full Text
Peer Reviewed
See detailModel Updating Based on Frequency Response Functions Using A General Finite Element Code
Yan, Ai-Min; Golinval, Jean-Claude ULiege

in European Journal of Mechanical and Environmental Engineering (2003), 48(3), 149-162

Model updating techniques using frequency response function (FRF) data are studied in this paper. The numerical techniques are discussed for implementation with a large commercial finite element (FE ... [more ▼]

Model updating techniques using frequency response function (FRF) data are studied in this paper. The numerical techniques are discussed for implementation with a large commercial finite element (FE ) code. System equivalent reduction expansion process is adopted to reduce the complete FE solutions onto the experimental degrees of freedom. The rank-deficiency difficulty with this method is overcome using either of two numerical techniques: diagonal perturbation and singular value decomposition. This second technique is also used in solving the updating equation. Experimental FRF data are compared with the FE solutions, and the updated model parameters are obtained via an iteration procedure. A simplified frequency domain assurance criterion is proposed to evaluate the correlation between the FE model and the measured structure at the chosen frequencies. After verifying the efficiency of the methods with several benchmark tests, the program is applied to an aeroplane model test. Some conclusions are given and remaining problems illustrated. [less ▲]

Detailed reference viewed: 113 (2 ULiège)
Full Text
Peer Reviewed
See detailNonlinear thin shell finite element for steel and concrete structures subjected to fire: verification and validation
Talamona, Didier; Castagne, Sylvie; Franssen, Jean-Marc ULiege

in Journal of Applied Fire Science (2003), 12(1), 65-81

This article presents verification and validation examples for a nonlinear thin shell element developed for structures subjected to fire. The verification benchmarks are: a Z-shaped cantilever, a twisted ... [more ▼]

This article presents verification and validation examples for a nonlinear thin shell element developed for structures subjected to fire. The verification benchmarks are: a Z-shaped cantilever, a twisted cantilever beam, a hemispherical shell, and Lee's frame at room temperature and at elevated temperature. The element shows that it provides results in good agreement with theoretical results and other finite elements. The validation calculations have been performed on an H rolled profile and a concrete slab. The element demonstrates its ability to reproduce local buckling on a H-steel beam under fire conditions and that it predicts accurately the failure of a concrete slab subjected to fire. The theoretical development of this finite element has been published in the Journal of Applied Fire Science, Vol. 11, No. 4, pp. 291-310, "Nonlinear Thin Shell Finite Element for Steel and Concrete Structures Subjected to Fire: Theoretical Development." [less ▲]

Detailed reference viewed: 53 (1 ULiège)
Full Text
Peer Reviewed
See detailL'herpèsvirus alcélaphin 1, l'agent responsable de la forme africaine du coryza gangreneux
Dewals, Benjamin G ULiege; Boudry, Christel ULiege; Markine-Goriaynoff, Nicolas ULiege et al

in Annales de Médecine Vétérinaire (2003), 147(1, FEB-MAR), 1-15

Malignant catarrhal fever (MCF) is a pathology usually lethal which has been described in a large number of ruminant species. Based on the etiology, two main forms of MCF have been described, i.e., the ... [more ▼]

Malignant catarrhal fever (MCF) is a pathology usually lethal which has been described in a large number of ruminant species. Based on the etiology, two main forms of MCF have been described, i.e., the European and the African forms due to ovine herpesvirus 2 (OvHV-2) and alcelaphine herpesvirus 1 (AlHV-1), respectively. The present review is devoted to the African form of MCF and to its causative agent AlHV-1. AlHV-1 belongs to the Gammaherpesvirinae subfamily of the Herpesviridae family. Wildebeests (Connochaetes spp) carry AlHV-1, which is lethal for a large number of ruminant species, while apparently harmless to its natural host. In hosts susceptible to MCF, the pathology is characterized by fever, extensive lymphadenopathy, ulcerative lesions of the digestive and the upper respiratory tracts mucous membranes and severe keratoconjunctivitis. In the present paper, we will review the data available to date on AlHV-1 and on the African form of MCF with emphasis on the pathogenesis, clinical signs and anatomo-pathological lesions of MCF. Finally, we will discuss the relationship between AlHV-1 and wildebeest as an example of symbiosis between a virus and its natural host. [less ▲]

Detailed reference viewed: 104 (32 ULiège)
Full Text
Peer Reviewed
See detailA time–frequency technique for the stability analysis of impulse responses from nonlinear aeroelastic systems
Dimitriadis, Grigorios ULiege; Cooper, Jonathan E

in Journal of Fluids & Structures (2003), 17(8), 11811201

A time–frequency method is proposed for the analysis of response time histories from nonlinear aeroelastic systems. The approach is based on a time-varying curve-fit of the short time Fourier transform of ... [more ▼]

A time–frequency method is proposed for the analysis of response time histories from nonlinear aeroelastic systems. The approach is based on a time-varying curve-fit of the short time Fourier transform of the impulse response. It is shown that the method can be used in order to obtain a clear picture of the sub-critical stability of a number of aeroelastic systems with a variety of structural and aerodynamic nonlinearities. Additionally, frequency and amplitude information can be obtained for both the linear and nonlinear signatures of the response signals in the sub- and postcritical regions. Finally, it is shown that, given certain types of nonlinear functions, sub-critical damping trends can be extrapolated to predict bifurcation airspeeds. [less ▲]

Detailed reference viewed: 23 (1 ULiège)
Full Text
See detailLe Musée en Piconrue de Bastogne
Donneau, Olivier ULiege

in Invitation au musée : Courrier du patrimoine culturel de la Communauté française (2003), 4

Courte présentation des activités du Musée en Piconrue de Bastogne.

Detailed reference viewed: 22 (3 ULiège)
Full Text
Peer Reviewed
See detailNegative association between smoking and anti-saccharomyces cerevisiae antibodies in Crohn's disease
Van Kemseke, Catherine ULiege; Belaiche, Jacques ULiege; Steeman, C. et al

in Acta Gastro-Enterologica Belgica (2003), 66(1, Jan-Mar), 1-6

Background: Crohn's disease (CD) is a polygenic multifactorial heterogeneous disease. Anti-Saccharomyces Cerevisiae antibodies (ASCA) correlate highly with CD and are present in 50-80% of patients. The ... [more ▼]

Background: Crohn's disease (CD) is a polygenic multifactorial heterogeneous disease. Anti-Saccharomyces Cerevisiae antibodies (ASCA) correlate highly with CD and are present in 50-80% of patients. The reason for ASCA positivity or negativity in CD is unknown. The aim of our work was to analyse clinical, epidemiological and genetic characteristics in ASCA + or ASCA- CD patients. Methods : 113 patients with CD were tested for ASCA (IgA and IgG) by using a commercial kit (Medipan Diagnostica). Age, gender, systemic manifestations, familial form of disease, age at diagnosis, location and behaviour of the disease, smoking habit as well as genotyping for -308 TNF gene polymorphisms were determined. Results : 38.9% CD patients were negative for both IgA and IgG ASCA while 61.1% were ASCA positive (respectively IgA and IgG : 31.9%; IgA only : 9.7%; IgG only : 19.5%). The only significant difference between ASCA+ and ASCA- patients was for smoking habit : there were 29% smokers in ASCA+ versus 50% in ASCA- CD patients (P = 0.03). This low proportion of smokers was more prominent in ASCA IgA+ patients than in isolated ASCA IgG+ patients (25.6% versus 45.5%) and was minimal in patients with high titers of ASCA IgA (0/8). Logistic regression showed smoking habit still borderline for significance (P = 0.057). Conclusions : Our results suggest a negative association between smoking and ASCA positivity in CD. This association was more prominent for ASCA IgA+. It indicates that smoking habit should be taken into account when analysing ASCA status in CD patients and may suggest an influence of smoking on immunization against intestinal material. [less ▲]

Detailed reference viewed: 52 (0 ULiège)
Full Text
Peer Reviewed
See detailComparison of aquifer vulnerability assessment techniques. Application to the Neblon river basin (Belgium)
Gogu, Radu Constantin; Hallet, Vincent; Dassargues, Alain ULiege

in Environmental Geology (2003), 44(8), 881-892

Five different methods for assessing intrinsic aquifer vulnerability were tested in a case study and their results compared. The test area was a slightly karstified district in the Condroz region of ... [more ▼]

Five different methods for assessing intrinsic aquifer vulnerability were tested in a case study and their results compared. The test area was a slightly karstified district in the Condroz region of Belgium. The basin covers about 65 km(2) and the karst aquifer provides a water-supply of about 28,000 m(3)d(-1). The methods tested were: EPIK (Doerfliger et al. 1999), DRASTIC (Aller et al.1987), 'German method' (von Hoyer and Sofner 1998), GOD (Foster 1987) and ISIS (Civita and De Regibus 1995). The results are compared and critically examined. From the analysis, it seems that reducing the number of parameters is unsatisfactory, due to the variety of geological conditions. The various methods produce very different results at any given site. As only physically-based methods can be checked for their reliability, it is clear that future vulnerability mapping techniques must incorporate such methods. [less ▲]

Detailed reference viewed: 183 (14 ULiège)
Full Text
Peer Reviewed
See detailp-mode Oscillations of alpha Cen A
Thoul, Anne ULiege; Scuflaire, Richard ULiege; Vatovez, B. et al

in Astrophysics & Space Science (2003), 284

Models of alpha Cen A & B have been computed using the masses determined by Pourbaix et al. (2002) and the data derived from the spectroscopic analysis of Neuforge and Magain (1997). The seismological ... [more ▼]

Models of alpha Cen A & B have been computed using the masses determined by Pourbaix et al. (2002) and the data derived from the spectroscopic analysis of Neuforge and Magain (1997). The seismological data obtained by Bouchy and Carrier (2001, 2002) do help improve our knowledge of the evolutionary status of the system. All the constraints are satisfied with a model which gives an age of about 6 Gyr for the binary. [less ▲]

Detailed reference viewed: 34 (8 ULiège)
Full Text
Peer Reviewed
See detailCalibration of ion effective temperatures achieved by resonant activation in a quadrupole ion trap
Gabelica, Valérie ULiege; Karas, Michael; De Pauw, Edwin ULiege

in Analytical Chemistry (2003), 75(19), 5152-5159

The present paper describes a calibration of the ion effective temperatures as a function of the resonant activation amplitude in a quadrupole ion trap mass spectrometer. MS/MS experiments are performed ... [more ▼]

The present paper describes a calibration of the ion effective temperatures as a function of the resonant activation amplitude in a quadrupole ion trap mass spectrometer. MS/MS experiments are performed on leucine enkephalin (M + H)(+), bradykinin (M + H)(+), (M + 2H)(2+), and (M + 3H)(3+), and ubiquitin (M + 11H)(11+). For each amplitude, the effective temperature is calculated as the temperature that would give the same dissociation rate constant as the one observed and is calculated using published Arrhenius parameters. The effective temperature is found to be linearly dependent on the activation amplitude on the range investigated. The dependence of the slope and of the intercept of the T-eff = f (amplitude) functions on the parent ion m/z is examined and an equation is derived to calibrate the ion effective temperature between 365 and 600 K Below 365 K, a deviation from linearity is expected. Above 600 1 the validity of the equation will depend on whether the rapid energy exchange limit is still reached. Calculating backward, the Arrhenius parameters from the measured dissociation rates using this calibration show excellent agreement with the published values. The calibration can therefore be used to determine Arrhenius activation parameters from dissociation kinetics under resonant activation in quadrupole ion trap mass spectrometers. [less ▲]

Detailed reference viewed: 49 (1 ULiège)
Full Text
Peer Reviewed
See detailA review of the major causes of digestive disorders in the European rabbit
Marlier, Didier ULiege; Dewrée, Roxane; Delleur, Valéry et al

in Annales de Médecine Vétérinaire (2003), 147(6, DEC-JAN), 385-392

Digestive diseases frequently occur in rabbitries, inducing high mortality rates and huge economic losses. The major causes of these pathological conditions are described in this review. The current state ... [more ▼]

Digestive diseases frequently occur in rabbitries, inducing high mortality rates and huge economic losses. The major causes of these pathological conditions are described in this review. The current state of knowledge on two diseases of unknown origin, the so called Rabbit Epizootic Enteropathy and Mucoid Enteropathy is also presented. [less ▲]

Detailed reference viewed: 123 (12 ULiège)
Full Text
See detailUn monde de rejetés
Dumortier, Jean-Louis ULiege

in Traces (2003), 14

Detailed reference viewed: 15 (0 ULiège)
Full Text
Peer Reviewed
See detailDistinction Between Cultivated And Wild Chicory Gene Pools Using Aflp Markers
Van Cutsem, P.; Du Jardin, Patrick ULiege; Boutte, C. et al

in Theoretical & Applied Genetics = Theoretische und Angewandte Genetik (2003), 107(4),

Detailed reference viewed: 19 (2 ULiège)
Full Text
Peer Reviewed
See detailAn Improved Method of Photometric Mode Identification: Applications to Slowly Pulsating B, beta Cephei, delta Scuti and gamma Doradus Stars
Dupret, Marc-Antoine ULiege; Scuflaire, Richard ULiege; Noels-Grötsch, Arlette ULiege et al

in Astrophysics & Space Science (2003), 284

We present an improved version of the method of photometric mode identification based upon the inclusion of non-adiabatic eigenfunctions determined in the stellar atmosphere, according to the formalism ... [more ▼]

We present an improved version of the method of photometric mode identification based upon the inclusion of non-adiabatic eigenfunctions determined in the stellar atmosphere, according to the formalism recently proposed by Dupret et al. (2002). We apply our method to beta Cephei, Slowly Pulsating B, delta Scuti and gamma Doradus stars. Besides identifying the degree l of the pulsating stars, our method is also a tool for improving the knowledge of stellar interiors and atmospheres, by imposing constraints on the metallicity for beta Cephei and SPBs, the characteristics of the superficial convection zone for delta Scuti and gamma Doradus stars and the limb-darkening law. [less ▲]

Detailed reference viewed: 30 (4 ULiège)
Full Text
Peer Reviewed
See detailNote sous Cass., 29 novembre 2001
Biquet, Christine ULiege

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2003)

Detailed reference viewed: 26 (3 ULiège)
Full Text
Peer Reviewed
See detailLe passé récent, la réforme de l'impôt des personnes physiques, le cas des villes
Jurion, Bernard ULiege

in Bulletin de Documentation du Ministère des Finances (2003)

Detailed reference viewed: 41 (8 ULiège)
Full Text
Peer Reviewed
See detailCharacterisation of different inulin samples by DSC - Influence of polymerisation degree on melting temperature
Blecker, Christophe ULiege; Chevalier, J. P.; Fougnies, C. et al

in Journal of Thermal Analysis & Calorimetry (2003), 71(1), 215-224

Melting behaviour of powder inulin has been studied by differential scanning calorimetry. DSC curves show two endothermic peaks, relative to water elimination and to inulin melting, respectively. The ... [more ▼]

Melting behaviour of powder inulin has been studied by differential scanning calorimetry. DSC curves show two endothermic peaks, relative to water elimination and to inulin melting, respectively. The second peak is dependent on inulin type and a shift to a higher temperature is observed with increasing average polymerisation degree (DP) of the sample. For similar crystallinity index, linear relations have been underlined and so predicting inulin mean DP can be done by DSC analysis. The study shows that a relatively high heating rate (25degreesC min(-1)) can be used and brings a supplementary interest by an important reduction of analysis time. [less ▲]

Detailed reference viewed: 100 (19 ULiège)
Full Text
Peer Reviewed
See detailCytokinin levels in leaves, leaf exudate and shoot apical meristem of Arabidopsis thaliana during floral transition
Corbesier, Laurent; Prinsen, Els; Jacqmard, Annie ULiege et al

in Journal of Experimental Botany (2003), 54(392), 2511-2517

Understanding the complete picture of floral transition is still impaired by the fact that physiological studies mainly concern plant species whose genetics is poorly known, and vice versa. Arabidopsis ... [more ▼]

Understanding the complete picture of floral transition is still impaired by the fact that physiological studies mainly concern plant species whose genetics is poorly known, and vice versa. Arabidopsis thaliana has been successfully used to unravel signalling pathways by genetic and molecular approaches, but analyses are still required to determine the physiological signals involved in the control of floral transition. In this work, the putative role of cytokinins was investigated using vegetative plants of Arabidopsis (Columbia) induced to flower synchronously by a single 22 h long day. Cytokinins were analysed in leaf extracts, leaf phloem exudate and in the shoot apical meristem at different times during floral transition. It was found that, in both the leaf tissues and leaf exudate, isopentenyladenine forms of cytokinins increased from 16 h after the start of the long day. At 30 h, the shoot apical meristem of induced plants contained more isopentenyladenine and zeatin than vegetative controls. These cytokinin increases correlate well with the early events of floral transition. [less ▲]

Detailed reference viewed: 53 (2 ULiège)
Full Text
Peer Reviewed
See detailTrophic habits and aquatic microhabitat use in gilled immature, paedomorphic and metamorphic Alpine newts (Triturus alpestris apuanus) in a pond in central Italy
Denoël, Mathieu ULiege; Andreone, F.

in Belgian Journal of Zoology (2003), 133(2), 95-102

Current evolutionary models suggest that the presence of heterogeneous habitats favours the evolution of polymorphisms. In such cases, alternative phenotypes can coexist because they use different ... [more ▼]

Current evolutionary models suggest that the presence of heterogeneous habitats favours the evolution of polymorphisms. In such cases, alternative phenotypes can coexist because they use different resources. Facultative paedomorphosis is a heterochronic polymorphism in which a morph - the paedomorph - retains larval traits during the adult stage while the other morph - the metamorph - is fully metamorphosed. The aim of this study was to determine the microhabitat use and the diet of Alpine newt paedomorphs, metamorphs and immatures (Triturus alpestris apuanus) coexisting in a small pond in Tuscany, central Italy, i.e. in a habitat where dimorphism is not expected. Although the two adult morphs do not use exactly the same resources, resource partitioning was weaker than in deep Alpine lakes. Nevertheless, the diet of immature gilled newts (larvae) differed from that of adults (metamorphs and paedomorphs). While the larvae eat a large number of planktonic organisms, the adults focus on insect larvae and newt eggs. The differences in resource use favour the coexistence of aquatic juveniles and adults. In the studied pond, facultative paedomorphosis was previously shown to be favoured by a precocious maturity of the paedomorphs. This study shows that the coexistence of paedomorphs and metamorphs may also be supported by some dietary and spatial segregation, although any advantages gained by this pattern are rather limited in the adult stage. [less ▲]

Detailed reference viewed: 379 (23 ULiège)
Full Text
Peer Reviewed
See detailSoluble transferrin receptor for the evaluation of erythropoiesis and iron status.
Beguin, Yves ULiege

in Clinica Chimica Acta (2003), 329(1-2), 9-22

Iron transport in the plasma is carried out by transferrin, which donates iron to cells through its interaction with a specific membrane receptor, the transferrin receptor (TfR). A soluble form of the TfR ... [more ▼]

Iron transport in the plasma is carried out by transferrin, which donates iron to cells through its interaction with a specific membrane receptor, the transferrin receptor (TfR). A soluble form of the TfR (sTfR) has been identified in animal and human serum. Soluble TfR is a truncated monomer of tissue receptor, lacking its first 100 amino acids, which circulates in the form of a complex of transferrin and its receptor. The erythroblasts rather than reticulocytes are the main source of serum sTfR. Serum sTfR levels average 5.0+/-1.0 mg/l in normal subjects but the various commercial assays give disparate values because of the lack of an international standard. The most important determinant of sTfR levels appears to be marrow erythropoietic activity which can cause variations up to 8 times below and up to 20 times above average normal values. Soluble TfR levels are decreased in situations characterized by diminished erythropoietic activity, and are increased when erythropoiesis is stimulated by hemolysis or ineffective erythropoiesis. Measurements of sTfR are very helpful to investigate the pathophysiology of anemia, quantitatively evaluating the absolute rate of erythropoiesis and the adequacy of marrow proliferative capacity for any given degree of anemia, and to monitor the erythropoietic response to various forms of therapy, in particular allowing to predict response early when changes in hemoglobin are not yet apparent. Iron status also influences sTfR levels, which are considerably elevated in iron deficiency anemia but remain normal in the anemia of inflammation, and thus may be of considerable help in the differential diagnosis of microcytic anemia. This is particularly useful to identify concomitant iron deficiency in a patient with inflammation because ferritin values are then generally normal. Elevated sTfR levels are also the characteristic feature of functional iron deficiency, a situation defined by tissue iron deficiency despite adequate iron stores. The sTfR/ferritin ratio can thus describe iron availability over a wide range of iron stores. With the exception of chronic lymphocytic leukemia (CLL) and high-grade non-Hodgkin's lymphoma and possibly hepatocellular carcinoma, sTfR levels are not increased in patients with malignancies. We conclude that soluble TfR represents a valuable quantitative assay of marrow erythropoietic activity as well as a marker of tissue iron deficiency. [less ▲]

Detailed reference viewed: 275 (0 ULiège)
Full Text
Peer Reviewed
See detailHaplotype diversity of the myostatin gene among beef cattle breeds
Dunner, S.; Miranda, M. E.; Amigues, Y. et al

in Genetics, Selection, Evolution (2003), 35(1, JAN-FEB), 103-118

A total of 678 individuals from 28 European bovine breeds were both phenotyped and analysed at the myostatin locus by the Single Strand Conformation Polymorphism (SSCP) method. Seven new mutations were ... [more ▼]

A total of 678 individuals from 28 European bovine breeds were both phenotyped and analysed at the myostatin locus by the Single Strand Conformation Polymorphism (SSCP) method. Seven new mutations were identified which contribute to the high polymorphism (1 SNP every 100 bp) present in this small gene; twenty haplotypes were described and a genotyping method was set up using the Oligonucleotide Ligation Assay (OLA) method. Some haplotypes appeared to be exclusive to a particular breed; this was the case for 5 in the Charolaise (involving mutation Q204X) and 7 in the Maine-Anjou (involving mutation E226X). The relationships between the different haplotypes were studied, thus allowing to test the earlier hypothesis on the origin of muscular hypertrophy in Europe: muscular hypertrophy (namely m821 (del11)) was mainly spread in different waves from northern Europe milk purpose populations in most breeds; however, other mutations (mostly disruptive) arose in a single breed, were highly selected and have since scarcely evolved to other populations. [less ▲]

Detailed reference viewed: 19 (4 ULiège)
Full Text
Peer Reviewed
See detailEvaluation of false transrectal ultrasonographic pregnancy diagnoses in sheep by measuring the plasma level of pregnancy-associated glycoproteins
Karen, A.; Beckers, Jean-François ULiege; Sulon, Joseph ULiege et al

in Reproduction Nutrition Development (2003), 43(6, NOV-DEC), 577-586

The present study was undertaken to investigate to what extent pregnancy diagnoses made by transrectal ultrasonography could be confirmed by measurements of plasma concentration of ovine pregnancy ... [more ▼]

The present study was undertaken to investigate to what extent pregnancy diagnoses made by transrectal ultrasonography could be confirmed by measurements of plasma concentration of ovine pregnancy-associated glycoproteins (ovPAG). A total of 424 Awassi x Merino ewes were synchronized for estrus and examined by transrectal ultrasonography. In Experiment 1, the ewes (n = 156) were repeatedly scanned in a standing position on d 29, 36 and 50 of gestation. Similarly, the ewes (n = 268) in Experiment 2 were scanned on d 24, 29 and 34 of gestation, but these ewes were fasted for 12 h prior to the examination and the abdominal wall of each animal was lifted up by the hands of the assistant during the scanning. Blood samples were withdrawn after each transrectal ultrasonographic examination in both experiments. Ovine PAG concentrations were measured in plasma by a heterologous radioimmunoassay and the cut-off value for pregnancy was greater than or equal to 1 ng.mL(-1). Based on the lambing performance, in Experiment 1, altogether 47 false negative and 38 false positive diagnoses were made by transrectal ultrasonography in 24 and 33 ewes, respectively between d 29 and 50 of gestation. In Experiment 2, altogether 8 false negative and 13 false positive diagnoses both were made in 7 ewes between d 24 and 34 of gestation. In both experiments, all ewes with false negative diagnoses had ovPAG concentrations higher than the threshold level for pregnancy diagnosis and all ewes with false positive diagnoses had ovPAG concentrations lower than the threshold of pregnancy. Furthermore, by the PAG-RIA test all lambed or aborted ewes (n = 63) were correctly diagnosed as pregnant and with three exceptions, all non-lambed ewes (n = 361) were correctly diagnosed as non-pregnant during the examined periods of both experiments. [less ▲]

Detailed reference viewed: 106 (0 ULiège)
Full Text
Peer Reviewed
See detailBinding and migration across fibronectin and VCAM-1 of cycling hematopoietic progenitor cells.
Gothot, André ULiege; Giet, Olivier ULiege; Huygen, Sandra et al

in Leukemia & Lymphoma (2003), 44(8), 1379-83

Using different experimental approaches, it has been established that transplantability of hematopoietic/stem progenitor cells is ineffective during transit through the cell cycle. Although primitive stem ... [more ▼]

Using different experimental approaches, it has been established that transplantability of hematopoietic/stem progenitor cells is ineffective during transit through the cell cycle. Although primitive stem cells are responsive to mitogenic stimulation in optimized ex vivo conditions, defective engraftment of generated cells may limit their detection in standard transplantation models as well as their use in clinical cell therapy. The activation level of adhesion receptors is modulated by stimulation of cytokine receptors via "inside-out" signaling. This prompted us to study the interactions of progenitor cells with fibronectin (Fn) in different phases of the cell cycle. We first demonstrated that adhesion to Fn was stimulated in S/G2 + M as compared to G0/G1, in ex vivo cultured CD34+ cells, with a predominant usage of very late antigen (VLA)-5 over that of VLA-4. We next determined that maximal Fn binding in active phases of the cell cycle limited cell motility toward stromal cell-conditioned medium. It was also observed that VLA-4 and VLA-5 ability to mediate adhesion or migration varied independently during cell cycle transit. Finally, in synchronized progenitor cells executing a first cell cycle ex vivo, a reversible increase in Fn binding was associated with a reversible decrease in adhesion to vascular cell-adhesion molecule (VCAM)-1. Overall, these observations suggest that defective engraftment of cycling stem/progenitor cells may result, at least in part, from abnormal trafficking related to changes in the activation level of adhesion receptors. [less ▲]

Detailed reference viewed: 54 (3 ULiège)
Full Text
See detailProgramme de cartographie hydrogéologique de la Région wallonne.
Dossin, F.; Bouezmarni, Mohamed ULiege; Habils, F. et al

in Eco Karst (2003), (57), 7-10

Detailed reference viewed: 34 (8 ULiège)
Full Text
Peer Reviewed
See detailThe inhibitor thiomandelic acid binds to both metal ions in metallo-beta-lactamase and induces positive cooperativity in metal binding.
Damblon, Christian ULiege; Jensen, Mikael; Ababou, Abdessamad et al

in Journal of Biological Chemistry (2003), 278(31), 29240-51

Thiomandelic acid is a simple, broad spectrum, and reasonably potent inhibitor of metallo-beta-lactamases, enzymes that mediate resistance to beta-lactam antibiotics. We report studies by NMR and ... [more ▼]

Thiomandelic acid is a simple, broad spectrum, and reasonably potent inhibitor of metallo-beta-lactamases, enzymes that mediate resistance to beta-lactam antibiotics. We report studies by NMR and perturbed angular correlation (PAC) spectroscopy of the mode of binding of the R and S enantiomers of thiomandelic acid, focusing on their interaction with the two metal ions in cadmium-substituted Bacillus cereus metallo-beta-lactamase. The 113Cd resonances are specifically assigned to the metals in the two individual sites on the protein by using 113Cd-edited 1H NMR spectra. Each enantiomer of thiomandelate produces large downfield shifts of both 113Cd resonances and changes in the PAC spectra, which indicate that they bind such that the thiol of the inhibitor bridges between the two metals. For R-thiomandelate, this is unambiguously confirmed by the observation of scalar coupling between Halpha of the inhibitor and both cadmium ions. The NMR and PAC spectra reveal that the two chiral forms of the inhibitor differ in the details of their coordination geometry. The complex with R-thiomandelate, but not that with the S-enantiomer, shows evidence in the PAC spectra of a dynamic process in the nanosecond time regime, the possible nature of which is discussed. The thiomandelate complex of the mononuclear enzyme can be detected only at low metal to enzyme stoichiometry; the relative populations of mononuclear and binuclear enzyme as a function of cadmium concentration provide clear evidence for positive cooperativity in metal ion binding in the presence of the inhibitor, in contrast to the negative cooperativity observed in the free enzyme. [less ▲]

Detailed reference viewed: 37 (5 ULiège)
Full Text
See detailLa Vie de saint Lambert du chanoine Nicolas (ca 1145) et l’élection du prince-évêque Henri de Leez (1145-1162)
Adam, Renaud ULiege

in Bulletin de l'Institut Archéologique Liégeois (2003), 111

Detailed reference viewed: 54 (5 ULiège)
Full Text
Peer Reviewed
See detailComment j'explore ... un nez rouge.
Pierard, Claudine ULiege; Henry, Frédérique ULiege; Rakic, L. et al

in Revue Médicale de Liège (2003), 58(7-8), 515-8

A red nose is a semiological sign shared in common by a series of diseases. The differential diagnosis is important to establish. A careful clinical examination often allows to reach the precise diagnosis ... [more ▼]

A red nose is a semiological sign shared in common by a series of diseases. The differential diagnosis is important to establish. A careful clinical examination often allows to reach the precise diagnosis. A skin biopsy is required when erythema is accompanied by a cutaneous infiltration suggesting some granulomatous and tumoral processes. [less ▲]

Detailed reference viewed: 72 (2 ULiège)
Full Text
See detailPour lire Pédigrée
Dumortier, Jean-Louis ULiege

in Dossiers L (Littérature française de Belgique (2003), 64(4),

Detailed reference viewed: 15 (1 ULiège)
Full Text
Peer Reviewed
See detailTwo new atrypid brachiopod species from the late Frasnian of Belgium
Mottequin, Bernard ULiege

in Bulletin de l'Institut Royal des Sciences Naturelles de Belgique. Sciences de la Terre (2003), 73

Two new species of atrypid brachiopods from the late Frasnian Lambermont and Barvaux formations of Belgium are described (south-east border of the Dinant and the Vesdre Nappe), Iowatrypa ultima n. sp. and ... [more ▼]

Two new species of atrypid brachiopods from the late Frasnian Lambermont and Barvaux formations of Belgium are described (south-east border of the Dinant and the Vesdre Nappe), Iowatrypa ultima n. sp. and Spinatrypa (Spinatrypa) lambermontensis n. sp. These species rank among the last representatives of the order Atrypida in the Ardennes (Upper Palmatolepis rhenana Zone). [less ▲]

Detailed reference viewed: 79 (14 ULiège)
Full Text
Peer Reviewed
See detailL'application dans le temps de la peine de travail
Jacobs, Ann ULiege

in Revue de Droit Pénal et de Criminologie (2003)

Detailed reference viewed: 36 (3 ULiège)
Full Text
Peer Reviewed
See detailApplication of the fast multipole method to the 2D finite element-boundary element analysis of electromechanical devices
V Sabariego, Ruth ULiege; Gyselinck, J.; Geuzaine, Christophe ULiege et al

in COMPEL (2003), 22(3), 659-673

The present paper deals with the fast multipole acceleration of the 2D finite element-boundary element modelling of electromechanical devices. It is shown that the fast multipole method, usually applied ... [more ▼]

The present paper deals with the fast multipole acceleration of the 2D finite element-boundary element modelling of electromechanical devices. It is shown that the fast multipole method, usually applied to large 3D problems, can also lead to a reduction in computational time when dealing with relatively small 2D problems, provided that an adaptive truncation scheme for the expansion of the 2D Laplace Green function is used. As an application example, the 2D hybrid modelling of a linear actuator is studied, taking into account saturation, the voltage supply and the mechanical equation. The computational cost without and with fast multipole acceleration is discussed for both the Linear and nonlinear case. [less ▲]

Detailed reference viewed: 228 (20 ULiège)
Full Text
Peer Reviewed
See detailDouble radial immunodiffusion as a tool to identify pregnancy-associated glycoproteins in ruminant and nonruminant placentae
El Amiri, B.; Melo de Sousa, Noelita ULiege; Mecif, K. et al

in Theriogenology (2003), 59(5-6), 1291-1301

Pregnancy-associated glycoproteins (PAGs) are antigens synthesized in the superficial layers of the ruminant trophoblast. Initially, they were identified either as proteins released into the maternal ... [more ▼]

Pregnancy-associated glycoproteins (PAGs) are antigens synthesized in the superficial layers of the ruminant trophoblast. Initially, they were identified either as proteins released into the maternal bloodstream (where they have applications in pregnancy diagnosis) (PAG1) or as molecules binding to the LH receptor (PAG2). In this study, double radial immunodiffusion was used to test the ability of antisera raised against different PAG molecules (bovine, ovine and caprine) to react with placental extracts from nonruminants (rabbit, cat, mouse, pig, and wild pig) and ruminants (cow, ewe, and goat). Placental extracts from all nonruminants tested except rabbit reacted with anti bovine PAG2 (anti-boPAG2). Extracts of ruminant placentas reacted with different antisera, confirming the expression of various PAG molecules. According to the time at which the placentas were collected (early or middle pregnancy), the reaction differed as regards the thickness, position, and number of precipitation lines, suggesting that PAG expression varies as pregnancy progresses. Bos indicus and Bos taurus placental extracts exhibited different reactions with anti-boPAG2: a single precipitation line in the former case and two lines in the latter. This suggests differential expression of boPAG2 related glycoproteins in these two subspecies. [less ▲]

Detailed reference viewed: 42 (0 ULiège)
Full Text
Peer Reviewed
See detailA recombinant 31.5 kDa keratinase and a crude exo-antigen from Microsporum canis fail to protect against a homologous experimental infection in guinea pigs.
Descamps, Frederic F; Brouta, Frederic; Vermout, Sandy M et al

in Veterinary Dermatology (2003), 14(6), 305-312

A Microsporum canis recombinant 31.5 kDa keratinase and a M. canis crude exo-antigen were tested as vaccines in an experimental infection model in guinea pigs. Animals were vaccinated subcutaneously three ... [more ▼]

A Microsporum canis recombinant 31.5 kDa keratinase and a M. canis crude exo-antigen were tested as vaccines in an experimental infection model in guinea pigs. Animals were vaccinated subcutaneously three times at two-week intervals with either the keratinase, the exo-antigen or the adjuvant alone. Cutaneous challenge was performed blindly. Both humoral and cellular-specific immune responses to M. canis antigens were evaluated every 14 days, while a blind evaluation of clinical lesion development and fungal persistency in skin were monitored weekly. Vaccination induced very high and significant (P < 0.01) antibody responses towards both antigens. High cell-mediated immune responses to both immunogens were also induced by vaccination. After challenge, however, scores reflecting the severity of dermatophytic lesions did not differ significantly between vaccinated and control groups at any time after challenge. These results suggest that, in the guinea pig, the induction of specific immune responses against the M. canis-secreted antigens used in this study are not protective against challenge exposure. [less ▲]

Detailed reference viewed: 41 (5 ULiège)
Full Text
Peer Reviewed
See detailCultures maraîchères et insectes utiles
Francis, Frédéric ULiege; Colignon, Pierre; Haubruge, Eric ULiege

in Le Canard déchaîné du Kauwberg (2003), 46

Detailed reference viewed: 57 (4 ULiège)
Full Text
Peer Reviewed
See detailUltrasound appearance of bowel wall in Wolman's disease.
NCHIMI LONGANG, Alain ULiege; Rausin, Leon; Khamis, Jamil

in Pediatric Radiology (2003), 33(4), 284-5

Detailed reference viewed: 15 (2 ULiège)
Full Text
Peer Reviewed
See detailLifting, Superadditivity, Mixed Integer Rounding and Single Node Flow Sets Revisited
Louveaux, Quentin ULiege; Wolsey, Laurence A.

in 4OR : Quarterly Journal of the Belgian, French and Italian Operations Research Societies (2003), 1

In this survey we attempt to give a unified presentation of a variety of results on the lifting of valid inequalities, as well as a standard procedure combining mixed integer rounding with lifting for the ... [more ▼]

In this survey we attempt to give a unified presentation of a variety of results on the lifting of valid inequalities, as well as a standard procedure combining mixed integer rounding with lifting for the development of strong valid inequalities for knapsack and single node flow sets. Our hope is that the latter can be used in practice to generate cutting planes for mixed integer programs. The survey contains essentially two parts. In the first we present lifting in a very general way, empha- sizing superadditive lifting which allows one to lift simultaneously different sets of variables. In the second, our procedure for generating strong valid inequalities consists of reduction to a knapsack set with a single continuous variable, construc- tion of a mixed integer rounding inequality, and superadditive lifting. It is applied to several generalizations of the 0-1 single node flow set. [less ▲]

Detailed reference viewed: 123 (19 ULiège)
Full Text
Peer Reviewed
See detailFestina lente: evidences for fast and slow learning processes and a role for sleep in human motor skill learning.
Maquet, Pierre ULiege; Laureys, Steven ULiege; Perrin, Fabien et al

in Learning & Memory (Cold Spring Harbor, N.Y.) (2003), 10(4), 237-9

Detailed reference viewed: 25 (2 ULiège)
Full Text
Peer Reviewed
See detailLa motivation du refus de prononcer une peine de travail
Jacobs, Ann ULiege

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2003)

Detailed reference viewed: 68 (8 ULiège)
Full Text
Peer Reviewed
See detailL’implication dans la recherche clinique : un chemin vers la psychanalyse
Naziri, Despina ULiege

in Revue Belge de Psychanalyse (2003), 40(printemps), 3-24

L'article débute par un bref rappel des liens entre psychologie clinique et modèle psychanalytique et de la spécificité de la recherche clinique. Puis j’illustrerai ce type de recherche à travers mon ... [more ▼]

L'article débute par un bref rappel des liens entre psychologie clinique et modèle psychanalytique et de la spécificité de la recherche clinique. Puis j’illustrerai ce type de recherche à travers mon travail sur le recours répétitif à l’avortement en explicitant mon cheminement, tant au niveau de la pensée que de l’expérience, et en reprenant quelques repères de mon itinéraire personnel. [less ▲]

Detailed reference viewed: 92 (8 ULiège)
Full Text
Peer Reviewed
See detailLa problématique de la résistance des pneumocoques aux antibiotiques
Marchal, Valérie; Melin, Pierrette ULiege; Hayette, Marie-Pierre ULiege et al

in Revue Médicale de Liège (2003), 58(11), 675-680

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia and it is also a common cause of sinusitis, otitis media, bacteremia and meningitis. The increasing resistance to ... [more ▼]

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia and it is also a common cause of sinusitis, otitis media, bacteremia and meningitis. The increasing resistance to antimicrobial agents, now endemic in many countries, reflects an uncontrolled use of antibiotics. A good antibiotics policy and vaccination are at the moment the only way to control efficaciously the increasing antibiotic resistance of Streptococcus pneumoniae [less ▲]

Detailed reference viewed: 58 (3 ULiège)
Full Text
Peer Reviewed
See detailRENO, a European Postmarket Surveillance Registry, confirms effectiveness of coronary brachytheraypy in routine clinical practice.
Coen, V; Serruys, P; Sauerwein, W et al

in International Journal of Radiation, Oncology, Biology, Physics (2003), 55(4), 1019-1026

Purpose: To assess, by a European registry trial, the clinical event rate in patients with discrete stenotic lesions of coronary arteries (de novo or restenotic) in single or multiple vessels (native or ... [more ▼]

Purpose: To assess, by a European registry trial, the clinical event rate in patients with discrete stenotic lesions of coronary arteries (de novo or restenotic) in single or multiple vessels (native or bypass grafts) treated with -radiation. Methods and Materials: Between April 1999 and September 2000, 1098 consecutive patients treated in 46 centers in Europe and the Middle East with the Novoste Beta-Cath System were included in Registry Novoste (RENO). Results: Six-month follow-up data were obtained for 1085 patients. Of 1174 target lesions, 94.1% were located in native vessels and 5.9% in a bypass graft; 17.7% were de novo lesions, 4.1% were restenotic, and 77.7% were in-stent restenotic lesions. Intravascular brachytherapy was technically successful in 95.9% of lesions. Multisegmental irradiation, using a manual pullback stepping maneuver to treat longer lesions, was used in 16.3% of the procedures. The in-hospital rate of major adverse cardiac events was 1.8%. At 6 months, the rate was 18.7%. Angiographic follow-up was available for 70.4% of the patients. Nonocclusive restenosis was seen in 18.8% and total occlusion in 5.7% of patients. A combined end point for late (30–180 days) definitive or suspected target vessel closure was reached in 5.4%, but with only 2% of clinical events. Multivariate analysis was performed for major adverse cardiac events and late thrombosis. Conclusion: Data obtained from the multicenter RENO registry study, derived from a large cohort of unselected consecutive patients, suggest that the good results of recent randomized controlled clinical trials can be replicated in routine clinical practice. © 2003 Elsevier Science Inc. [less ▲]

Detailed reference viewed: 42 (0 ULiège)