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Only a few cases of skin involvement have been reported, primarily in single case reports. We analyzed and present the clinical ... [more ▼]Skin infiltration in multiple myeloma (skin MM) is a rare clinical problem. Only a few cases of skin involvement have been reported, primarily in single case reports. We analyzed and present the clinical outcomes, immunohistochemistry and cytogenetic features, and relevant laboratory data on 53 biopsy-proven skin MM cases. The median time from MM diagnosis to skin involvement was 2 years. There appears to be an overrepresentation of immunoglobulin class A (IgA) and light chain disease in skin MM. We found no correlation between CD56 negative MM and skin infiltration. We found that skin MM patients presented in all MM stages (i.e. ISS stages I to III), and there was no preferential cytogenetic abnormality. Patients with skin MM carry a very poor prognosis with a median overall survival (OS) of 8.5 months as time from skin involvement. Moreover, patients with IgA disease and plasmablastic morphology appear to have a worse OS. [less ▲]Detailed reference viewed: 22 (3 ULg) Circadian dynamics in measures of cortical excitation and inhibition balanceChellappa, Sarah; Gaggioni, Giulia ; LY, Julien et alin Scientific Reports (2016), 6:33661Detailed reference viewed: 15 (3 ULg) Du stilus à la plume ... du chapeau. Quelques réflexions sur la notion de styleHoubart, Claudine in Bruxelles Patrimoines (2016), (18), Detailed reference viewed: 18 (3 ULg) Invasive and Non-invasive Electrical Pericranial Nerve Stimulation for the Treatment of Chronic Primary HeadachesD'Ostilio, Kevin ; MAGIS, Delphine in Current Pain and Headache Reports (2016), 20Chronic primary headaches are widespread disorders which cause significant quality of life and socioprofessional impairment. Available pharmacological treatments have often a limited efficacy and/or can ... [more ▼]Chronic primary headaches are widespread disorders which cause significant quality of life and socioprofessional impairment. Available pharmacological treatments have often a limited efficacy and/or can generate unbearable side effects. Electrical nerve stimulation is a well known non-destructive method of pain modulation which has been recently applied to headache management. In this review, we summarise recent advances in invasive and non-invasive neurostimulation techniques targeting pericranial structures for the treatment of chronic primary headaches, chiefly migraine and cluster headache: occipital nerve, supraorbital nerve, vagus nerve, and sphenopalatineganglion stimulations. Invasive neurostimulation therapies have offered a new hope to drug-refractory headache sufferers but are not riskless and should be proposed only to chronic patients who failed to respond to most existing preventives. Non-invasive neurostimulation devices are user-friendly, safe and well tolerated and are thus taking an increasing place in the multidisciplinary therapeutical armamentarium of primary headaches. [less ▲]Detailed reference viewed: 12 (2 ULg) Macro-economic factors influencing the architectural business model shift in the pharmaceutical industryDierks, Raphaela Marie Louisa ; Bruyère, Olivier ; Reginster, Jean-Yves et alin Expert Review of Pharmacoeconomics & Outcomes Research (2016), First onlineIntroduction: Technological innovations, new regulations, increasing costs of drug productions and new demands are only few key drivers of a projected alternation in the pharmaceutical industry and its ... [more ▼]Introduction: Technological innovations, new regulations, increasing costs of drug productions and new demands are only few key drivers of a projected alternation in the pharmaceutical industry and its underlying business model. Despite significant articles in the press, there is little medical and economic evidence on the rationale driving the transformation from the traditional Research & Development (R&D) model to new alternative business models, such as Mergers & Acquisitions (M&A). The purpose of this review is to understand the macro-economic factors responsible for the revolution of the pharmaceutical business model, by understanding the needs, desires, new behavioral patterns, but also challenges within the industry. Considering these changes will be the key to possessing a competitive advantage over the market players. Areas covered: Existing literature on new macro-economic factors changing the pharmaceutical landscape has been reviewed to present a clear image of the current market environment. Expert commentary: Literature and media sources show that pharmaceutical companies are facing an architectural alteration in their business model, with more M&A deals and collaborations headlining the papers. Although Q1 2016 did show a major slowdown in M&A deals by volume since 2013 (with deal cancellations of Pfizer and Allergan, or the downfall of Valeant) pharmaceutical analysts remain confident that this shortfall was a consequence of the equity market volatility. It seems likely that the shift to an M&A model will become apparent during the remainder of 2016, with deal announcements such as Abbott Laboratories, AbbVie and Sanofi worth USD 45billion [1] showing the appetite of big pharma companies to shift from the fully vertical integrated business model to more horizontal business models. [less ▲]Detailed reference viewed: 28 (6 ULg) L'EBM peut-elle encore enthousiasmer ?Henrard, Gilles in Minerva: Tijdschrift Voor Evidence Based Medicine (2016)Detailed reference viewed: 7 (0 ULg) La responsabilité du supérieur hiérarchique devant la Cour pénale internationale : une première synthèse à la lumière du jugement prononcé dans l’affaire BembaWery, Marine ; Deprez, Christophe in Revue de la Faculté de Droit de l'Université de Liège (2016), 2Le 21 mars 2016, au terme d’une procédure longue de huit années, la Cour pénale internationale (CPI) prononça un verdict de culpabilité à l’encontre de Jean-Pierre Bemba. L’une des innovations majeures ... [more ▼]Le 21 mars 2016, au terme d’une procédure longue de huit années, la Cour pénale internationale (CPI) prononça un verdict de culpabilité à l’encontre de Jean-Pierre Bemba. L’une des innovations majeures liées à cette affaire concerne le vecteur d’imputabilité mobilisé par les juges. Pour la première fois dans l’histoire de la CPI, une chambre de première instance s’est dégagée des modes traditionnels de responsabilité prévus à l’article 25 du Statut de Rome pour sceller le sort d’un accusé sur la base de l’article 28 du même instrument, en application duquel la responsabilité pénale d’un supérieur hiérarchique peut être mise en cause en lien avec les actes commis par ses subordonnés. Par cette contribution, nous proposons d’examiner le verdict du 21 mars 2016, mais aussi les quelques pistes jurisprudentielles préexistantes, afin d’ébaucher une première synthèse du mécanisme de responsabilité du supérieur hiérarchique devant la CPI. [less ▲]Detailed reference viewed: 27 (8 ULg) La Paméla de Voltaire des Lumières au XXIe siècle - changements de statut et réception générique du texteDaubercies, Laurence in Loxias : Littératures Française et Comparées (2016)Detailed reference viewed: 16 (0 ULg) L’administration Obama, a t-elle (vraiment) navigué à vue sur la scène mondiale ?Santander, Sébastian in Recherches internationales (2016), 106Dès son arrivée au pouvoir, Obama a pris le soin de tenir un discours de rupture avec son prédécesseur dont l’action interventionniste et belliqueuse avait terni l’image des ÉU dans le monde. Il a sous ... [more ▼]Dès son arrivée au pouvoir, Obama a pris le soin de tenir un discours de rupture avec son prédécesseur dont l’action interventionniste et belliqueuse avait terni l’image des ÉU dans le monde. Il a sous-entendu qu’il ne se laisserait pas enfermer dans des cadres idéologiques et qu’il privilégierait une approche « pragmatique » et « souple », et fait savoir qu’il n’engagerait plus les ÉU dans des opérations militaires de grande envergure. Ce discours d’une approche au cas par cas combiné à la politique du retrait militaire d’Irak et d’Afghanistan, et au fait que Obama a parfois été amené à adopter une attitude réactive pour répondre aux soubresauts de l’actualité internationale ont alimenté la perception dominante selon laquelle cette administration se désintéressait et se désengageait du monde, et déployait une politique étrangère marquée par l’indécision, l’improvisation et l’absence de vision à long terme. On ne peut omettre que cette administration a parfois du adapter et ajuster sa politique en fonction des événements internationaux. Faut-il pour autant conclure que sous Obama la première puissance mondiale a navigué à vue sur la scène internationale ? [less ▲]Detailed reference viewed: 101 (59 ULg) Comment j'explore... une dysmorphose dento-maxillo-faciale.Urbain, Valérie; GILON, Yves ; BRUWIER, Annick et alin Revue Médicale de Liège (2016), 71(9), 394-399Dento-maxillofacial dysmorphoses represent a considerable area of maxillofacial surgery. Their incidence has constantly been on the rise since the beginning of the century. This can be explained by ... [more ▼]Dento-maxillofacial dysmorphoses represent a considerable area of maxillofacial surgery. Their incidence has constantly been on the rise since the beginning of the century. This can be explained by variations in the food and society habits.We will first discuss the various causes (congenital and environnemental) and the pathophysiology of these disorders. Then, we will separate them according to the skeletal and Angle’s classifications. We will examine the predictive criteria of these dysmorphoses from the youngest age and consider their clinical and cephalometrical diagnosis We will envisage their functional and aesthetic consequences and expose the preventive options. Finally, we will describe the orthodontic and surgical treatment available today and conclude that surgery remains the gold standard by restoring the conventional axis. [less ▲]Detailed reference viewed: 18 (2 ULg) Cooperative spontaneous emission from indistinguishable atoms in arbitrary motional quantum statesDamanet, François ; Braun, Daniel; Martin, John in Physical Review A (2016), 94We investigate superradiance and subradiance of indistinguishable atoms with quantized motional states, starting with an initial total state that factorizes over the internal and external degrees of ... [more ▼]We investigate superradiance and subradiance of indistinguishable atoms with quantized motional states, starting with an initial total state that factorizes over the internal and external degrees of freedom of the atoms. Due to the permutational symmetry of the motional state, the cooperative spontaneous emission, governed by a recently derived master equation [F. Damanet et al., Phys. Rev. A 93, 022124 (2016)], depends only on two decay rates γ and γ0 and a single parameter dd describing the dipole-dipole shifts. We solve the dynamics exactly for N = 2 atoms, numerically for up to 30 atoms, and obtain the large-N limit by a mean-field approach. We find that there is a critical difference γ0 − γ that depends on N beyond which superradiance is lost. We show that exact nontrivial dark states (i.e., states other than the ground state with vanishing spontaneous emission) only exist for γ = γ0 and that those states (dark when γ = γ0) are subradiant when γ < γ0. [less ▲]Detailed reference viewed: 9 (4 ULg) Relation entre hygiène bucco-dentaire et tendinopathies chez les sportifsKipgen, Laurence; Kaux, Jean-François ; Rompen, Eric et alin Science & Sports (2016), 31(4), 227-229Detailed reference viewed: 21 (1 ULg) Alligator Records- 45è anniversaire-Interview Bruce IglauerSacré, Robert in ABS Magazine (2016), (51), 8-17Alligator Records (Chicago,IL.) 45 ans au service du BluesDetailed reference viewed: 16 (0 ULg) Revealed preference tests of collectively rational consumption behavior: formulations and algorithmsTalla Nobibon, Fabrice; Cherchye, Laurens; Crama, Yves et alin Operations Research (2016), onlineThis paper focuses on revealed preference tests of the collective model of household consumption. We start by showing that the decision problems corresponding to testing collective rationality are {\sc np ... [more ▼]This paper focuses on revealed preference tests of the collective model of household consumption. We start by showing that the decision problems corresponding to testing collective rationality are {\sc np}-complete. This makes the application of these tests problematic for (increasingly available) large(r) scale data sets. We then present two approaches to overcome this negative result. First, we introduce exact algorithms based on mixed-integer programming ({\sc mip}) formulations of the collective rationality tests, which can be usefully applied to medium sized data sets. Next, we propose simulated annealing heuristics, which allow for efficient testing of the collective model in the case of large data sets. We illustrate our methods by a number of computational experiments based on Dutch labor supply data. [less ▲]Detailed reference viewed: 102 (10 ULg) « Oiseaux blessés. Avec les stagiaires d’Article 23 »Melice, Anne in Centre Franco Basaglia – Liège, Mouvement pour une psychiatrie démocratique dans le milieu de vie. (2016)Après une synthèse de récits de vie recueillis auprès de stagiaires rencontrés au sein des ateliers de l’Asbl Article 23 (Horeca et Bâtiment), ce texte décrit l’accueil qu’ils m’y ont réservé. Ce récit se ... [more ▼]Après une synthèse de récits de vie recueillis auprès de stagiaires rencontrés au sein des ateliers de l’Asbl Article 23 (Horeca et Bâtiment), ce texte décrit l’accueil qu’ils m’y ont réservé. Ce récit se prolongera dans le texte suivant intitulé « ‘’Je te porte dans moi comme un oiseau blessé’’ (Aragon) », qui se fera l’écho de mon observation de l’hospitalité propre aux ateliers d’Article 23. [less ▲]Detailed reference viewed: 14 (0 ULg) Congenital venous aneurysm of the right external jugular vein in a great daneLefebvre, Michaël ; Merveille, Anne-Christine ; Rizza, Maïlis et alin Veterinary Record Case Reports (2016)Detailed reference viewed: 14 (0 ULg) Visual and auditory cortical evoked potentials in interictal episodic migraine: An audit on 624 patients from three centres.Ambrosini, Anna; Kisialou, A; Coppola, Gianluca et alin Cephalalgia : An International Journal of Headache (2016)Detailed reference viewed: 11 (1 ULg) Le décret décumul et le Parlement wallonGrandjean, Geoffrey ; Janssens, Frédéricin Administration Publique: Revue du Droit Public et des Sciences Administratives (2016), 2Detailed reference viewed: 7 (0 ULg) Will climate change affect insect pheromonal communication?Boullis, Antoine ; Detrain, Claire; Francis, Frédéric et alin Current Opinion in Insect Science (2016)Understanding how climate change will affect species interactions is a challenge for all branches of ecology. We have only limited understanding of how increasing temperature and atmospheric CO2 and O3 ... [more ▼]Understanding how climate change will affect species interactions is a challenge for all branches of ecology. We have only limited understanding of how increasing temperature and atmospheric CO2 and O3 levels will affect pheromone-mediated communication among insects. Based on the existing literature, we suggest that the entire process of pheromonal communication, from production to behavioural response, is likely to be impacted by increases in temperature and modifications to atmospheric CO2 and O3 levels. We argue that insect species relying on long-range chemical signals will be most impacted, because these signals will likely suffer from longer exposure to oxidative gases during dispersal. We provide future directions for research programmes investigating the consequences of climate change on insect pheromonal communication. [less ▲]Detailed reference viewed: 22 (2 ULg) Psychological transition and adjustment processes related to retirement: Influence on cognitive functioningGrotz, Catherine ; Matharan, Fanny; Pérès, Karine et alin Aging & Mental Health (2016)Objective: To investigate the relationship between psychological transition and adjustment to retirement and cognitive performances in older adults. Methods: The study’s sample was taken from the Approche ... [more ▼]Objective: To investigate the relationship between psychological transition and adjustment to retirement and cognitive performances in older adults. Methods: The study’s sample was taken from the Approche Multidisciplinaire Int egr ee cohort, a French prospective study of retirees from agriculture, aged 65 and over, living in rural settings in southwestern France. The cross-sectional analyses were conducted on a sample of 590 elderly people without dementia at baseline and for whom information on perception of the work setting, experience of the retirement transition and adaptation to retirement life (nine variables) as well as neuropsychological measures (global cognitive functioning, episodic memory, verbal fluency, attention and psychomotor speed) were available at first visit. Results: Multivariable linear regression analyses, including nine variables related to retirement and adjusted for potential confounding factors, indicated that three of them positive consideration of former work situation, development of new activities during retirement and good adaptation to free time were associated with better cognitive performances. Conclusions: We found that several factors proved to be determinants of good cognitive functioning at retirement and could serve as a basis for the development of more efficient intervention programs aimed at helping retirees to maintain good cognitive functioning after retirement. [less ▲]Detailed reference viewed: 18 (3 ULg) Systemic biomarkers of collagen and elastin turnover are associated with clinically relevant outcomes in COPD.Stolz, Daiana; Leeming, Diana Julie; Edfort Kristensen, Jacob Hull et alin CHEST (2016)BACKGROUND: Extracellular matrix remodeling (ECM) of the lung tissue releases protein fragments into the blood, where they may be detected as serological surrogate markers of disease activity in chronic ... [more ▼]BACKGROUND: Extracellular matrix remodeling (ECM) of the lung tissue releases protein fragments into the blood, where they may be detected as serological surrogate markers of disease activity in chronic obstructive pulmonary disease (COPD). We aimed to assess the association of ECM turnover with severity and outcome of COPD. METHODS: In a prospective, observational, multicenter study including 506 patients with COPD, GOLD grades II-IV, we analyzed serum samples at stable state, exacerbation and 4 weeks after exacerbation, for a panel of 5 novel neo-epitopes including fragments of collagen type-III (C3M) and type-VI (C6M), pro-forms of collagen type-III (Pro-C3) and type-VI (Pro-C6) and neutrophil elastase-generated fragments of elastin (EL-NE) by ELISA. These neo-epitopes were also measured at stable state in a derivation cohort including 100 COPD patients. RESULTS: Serum levels of C3M, C6M, Pro-C3, Pro-C6 and EL-NE were associated with lung function. Patients with the lowest levels of Pro-C3 and Pro-C6 had more severe airflow limitation, hyperinflation, air trapping, and emphysema. Degradation of collagen type-III and -VI was associated with dyspnea. All ECM biomarkers, except Pro-C6, were increased at exacerbation as compared to stable state but, except EL-NE, did not differ between stable state and exacerbation follow-up in the crude and adjusted analyses. In Cox regression adjusted analyses, Pro-C3 was associated with a shorter time to exacerbation (HR 0.72[0.59-0.89] p=0.002) and Pro-C6 with survival (HR 2.09[1.18-3.71], p=0.011). CONCLUSIONS: Serum biomarkers of ECM turnover are significantly associated with disease severity and clinically relevant outcomes in COPD. [less ▲]Detailed reference viewed: 9 (1 ULg) Fertility progression in Germany: an analysis using flexible nonparametric cure survival modelsBremhorst, Vincent; Kreyenfeld, Michaela; Lambert, Philippe in Demographic Research (2016)OBJECTIVE This paper uses data from the German Socio-Economic Panel (GSOEP) to study the transition to second and third births. In particular, we seek to distinguish the factors that determine the timing ... [more ▼]OBJECTIVE This paper uses data from the German Socio-Economic Panel (GSOEP) to study the transition to second and third births. In particular, we seek to distinguish the factors that determine the timing of fertility from the factors that influence ultimate parity progression. METHODS We employ cure survival models, a technique commonly used in epidemiological studies and in the statistical literature but only rarely applied to fertility research. RESULTS We find that education has a different impact on the timing and the ultimate probability of having a second and a third birth. Furthermore, we show that the shape of the fertility schedule for the total population differs from that of ‘susceptible women’ (i.e., those who have a second or a third child). CONCLUSION Standard event history models conflate timing and quantum effects. Our approach overcomes this shortcoming. It estimates separate parameters for the hazard rate of having a next child for the ‘susceptible population’ and the ultimate probability of having another child for the entire population at risk. [less ▲]Detailed reference viewed: 67 (5 ULg) Evaluation of the Effect of Two Volatile Organic Compounds on Barley PathogensKaddes, Amine ; Parisi, Olivier ; Berhal, Chadi et alin Molecules (2016), 21(9), Detailed reference viewed: 23 (8 ULg) Determining new threshold temperatures for cooling and heating degree day index of different climatic zones of IranRoshan, Gh.R.; Ghanghermeh, A.A.; Attia, Shady in Renewable Energy : An International Journal (2016), 101(2017), 156-167Iran is a country with a variety of different climates. Determining the threshold temperatures suitable for providing thermal and climatic comfort is necessary and vital to its population well-being. This ... [more ▼]Iran is a country with a variety of different climates. Determining the threshold temperatures suitable for providing thermal and climatic comfort is necessary and vital to its population well-being. This research presents new threshold temperatures in order to calculate the degree day index required for heating and cooling by taking advantage of the 12 stations that are representative of the diversity of Iran's climate. Using Olgyay diagram, different bioclimatic ranges of 12 weather stations and their frequencies were compiled, processes and analysed. Mean daily data of temperature and relative humidity were used for the period of 1950e2010. Based on the frequencies of temperature readings falling in Olgyay's diagram comfort zone, representive temperature thresholds were selected based on 40 to 60 percentiles or (P20), 25e75% percentile (P50) and the threshold of 10e90% percentile. The findings of this study shows that Mashhad with 29.6% and Anzali with 2.33% of frequencies, have experienced the maximum and minimum days of comfort. After analyzing various percentiles to determine the threshold temperatures, it was observed that there is a little difference among the stations for determining the minimum threshold for the comfort. Differences are more obvious in the maximum thresholds. In total, minimum base temperatures (HDD) belonged to Ardabil stations that were 20.50, 20.90 and 20 deg C for P20, P50 and P80 respectively. The maximum temperature for calculating CDD with values of (P20 ¼ 25 C; P50 ¼ 26.25 C; P80 ¼ 27.50 C) is dedicated to Zabol station. The findings present more reasonable thermal comfort thresholds that can be used by architects, engineers and policy makers to achieve, in turn, more energy efficient homes and high quality indoor and outdoor living environments. [less ▲]Detailed reference viewed: 40 (4 ULg) Ageism in Belgium and Burundi: A comparative analysisMarquet, Manon ; Missotten, Pierre ; Schroyen, Sarah et alin Clinical Interventions in Aging (2016), 11Background: Recent cross-cultural comparisons between Asian and Western cultures have shown that ageism arises more from the lack of availability of social and economic resources for older adults than ... [more ▼]Background: Recent cross-cultural comparisons between Asian and Western cultures have shown that ageism arises more from the lack of availability of social and economic resources for older adults than from the culture itself. We tested this assumption by conducting a survey among people living in a least-developed country compared with a developed country. Methods: Twenty-seven Belgians living in Belgium, 29 Burundians living in Belgium and 32 Burundians living in Burundi were included in this study. Their attitudes toward older adults were assessed using several self-reported measures. Results: Statistical analyses confirmed that older people are more negatively perceived by Burundians living in Burundi than by Burundians and Belgians living in Belgium, whose attitudes did not differ from each other. Conclusion: Consistent with our hypothesis, our results suggest that the level of development of a country and more particularly the lack of government spending on older people (pension and healthcare systems) may contribute to their younger counterparts perceiving them more negatively. [less ▲]Detailed reference viewed: 41 (7 ULg) Graphene-multiferroic interfaces for spintronics applicationsZanolli, Zeila in Scientific Reports (2016)Graphene and magnetoelectric multiferroics are promising materials for spintronic devices with high performance and low energy consumption. A very long spin di usion length and high carrier mobility make ... [more ▼]Graphene and magnetoelectric multiferroics are promising materials for spintronic devices with high performance and low energy consumption. A very long spin di usion length and high carrier mobility make graphene attractive for spintronics. The coupling between ferroelectricity and magnetism, which characterises magnetoelectrics, opens the way towards unique device architectures. In this work, we combine the features of both materials by investigating the interface between graphene and BaMnO3, a magnetoelectric multiferroic. We show that electron charge is transferred across the interface and magnetization is induced in the graphene sheet due to the strong interaction between C and Mn. Depending on the relative orientation of graphene and BaMnO3, a quasi-half-metal or a magnetic semiconductor can be obtained. A remarkably large proximity induced spin splitting of the Dirac cones (~300 meV) is achieved. We also show how doping with acceptors can make the high-mobility region of the electronic bands experimentally accessible. This suggests a series of possible applications in spintronics (e.g. spin filters, spin injectors) for hybrid organic-multiferroic materials and reveals hybrid organic-multiferroics as a new class of materials that may exhibit exotic phenomena such as the quantum anomalous Hall effect and a Rashba spin-orbit induced topological gap. [less ▲]Detailed reference viewed: 17 (2 ULg) SO(10) models with flavour symmetries: Classification and examplesIvanov, Igor ; Lavoura, Luisin Journal of Physics : G Nuclear & Particle Physics (2016), 43(10), 105005Renormalizable SO(10) grand unified theory (GUT) models equipped with flavour symmetries are a popular framework for addressing the flavour puzzle. Usually, the flavour symmetry group has been an ad hoc ... [more ▼]Renormalizable SO(10) grand unified theory (GUT) models equipped with flavour symmetries are a popular framework for addressing the flavour puzzle. Usually, the flavour symmetry group has been an ad hoc choice, and no general arguments limiting this choice were known. In this paper, we establish the full list of flavour symmetry groups which may be enforced, without producing any further accidental symmetry, on the Yukawa-coupling matrices of an SO(10) GUT with arbitrary numbers of scalar multiplets in the ${\bf{10}}$, $\bar{{\bf{126}}}$, and ${\bf{120}}$ representations of SO(10). For each of the possible discrete non-Abelian symmetry groups, we present examples of minimal models which do not run into obvious contradiction with the phenomenological fermion masses and mixings. [less ▲]Detailed reference viewed: 7 (1 ULg) Ability of Tuta absoluta (Lepidoptera: Gelechiidae) to develop on alternative host plant speciesBawin, Thomas ; Dujeu, David; De Backer, Lara et alin Canadian Entomologist (2016), 148(4), 434-442The tomato leafminer, Tuta absoluta Meyrick (Lepidoptera: Gelechiidae), is a widespread devastating pest reported to develop on economically important solanaceous crops. The characterization of its host ... [more ▼]The tomato leafminer, Tuta absoluta Meyrick (Lepidoptera: Gelechiidae), is a widespread devastating pest reported to develop on economically important solanaceous crops. The characterization of its host range could help to understand and prevent the dispersion behavior of the insect in the environment. In this study, the ability of T. absoluta to develop on 12 cultivated or non-cultivated plants including Solanaceae, Chenopodiaceae, Convolvulaceae, Fabaceae and Malvaceae species under laboratory conditions was assessed. For each plant species, we monitored the development times of immature stages, survival, sex ratios and adult fecundity rates. All the 6 tested non-solanaceous plants, including Chenopodium, Convolvulus and Malva species, were not able to sustain (i.e. allow growth and development) T. absoluta larvae. Among Solanaceae, Solanum species were the most suitable host plants for the pest, but others could be opportunistically colonized with fewer incidences. T. absoluta appears to be strongly related to solanaceous plants which would predominantly support self-sustaining field populations. Preventing crop infestation by removing potential host plants in the immediate field vicinity and culture rotations with non-solanaceous crops is of primary importance. [less ▲]Detailed reference viewed: 74 (16 ULg) Two-Parameter Kinematic Approach for Shear Strength of Deep Concrete Beams with Internal FRP ReinforcementMihaylov, Boyan in Journal of Composites for Construction (2016), DOI: 10.1061/(ASCE)CC.1943-5614 .0000747Tests of deep concrete beams with internal fiber-reinforced polymer (FRP) reinforcement have shown that such members can exhibit lower shear strength than members with conventional steel reinforcement. To ... [more ▼]Tests of deep concrete beams with internal fiber-reinforced polymer (FRP) reinforcement have shown that such members can exhibit lower shear strength than members with conventional steel reinforcement. To model this effect, the current paper proposes an approach based on a two-parameter kinematic theory (2PKT) for conventional deep beams. The 2PKT is built on a kinematic model with two degrees of freedom that describes the deformation patterns of cracked beams. Using this theory shows that large strains in FRP longitudinal reinforcement result in reduced shear resistance of the critical loading zones (CLZ) of deep beams. The original 2PKT is therefore modified by introducing a reduction factor for the shear carried by the CLZ. The extended 2PKT approach is then applied to a database of 39 tests of FRP-reinforced deep beams from the literature, resulting in an average shear strength experimental-to-predicted ratio of 1.06 and a coefficient of variation of 18.3%. The results show that the 2PKT adequately captures the effects of the stiffness of the reinforcement, section depth, concrete strength, and shear-span-to-depth ratio on the shear strength of FRP-reinforced deep beams. [less ▲]Detailed reference viewed: 10 (3 ULg) MME mutation in dominant spinocerebellar ataxia with neuropathy (SCA43)Depondt; Donatello, Simona; Rai, Myriam et alin Neurology genetics (2016)Detailed reference viewed: 9 (1 ULg) Genomic Studies of Multiple Myeloma Reveal an Association between X Chromosome Alterations and Genomic Profile Complexity.Sticca, Tiberio ; CABERG, Jean-Hubert ; Wenric, Stéphane et alin Genes, Chromosomes & Cancer (2016)The genomic profile of multiple myeloma (MM) has prognostic value by dividing patients into a good prognosis hyperdiploid group and a bad prognosis non-hyperdiploid group with a higher incidence of IgH ... [more ▼]The genomic profile of multiple myeloma (MM) has prognostic value by dividing patients into a good prognosis hyperdiploid group and a bad prognosis non-hyperdiploid group with a higher incidence of IgH translocations. This classification, however, is inadequate and many other parameters like mutations, epigenetic modifications and genomic heterogeneity may influence the prognosis. We performed a genomic study by array-based comparative genomic hybridization (aCGH) on a cohort of 162 patients to evaluate the frequency of genomic gains and losses. We identified a high frequency of X chromosome alterations leading to partial Xq duplication, often associated with Xi deletion in female patients. This partial X duplication could be a cytogenetic marker of aneuploidy as it is correlated with a high number of chromosomal breakages. Patient with high level of chromosomal breakage had reduced survival regardless the region implicated. A higher transcriptional level was shown for genes with potential implication in cancer and located in this altered region. Among these genes, IKBKG and IRAK1 are members of the NFKB pathway which plays an important role in MM and is a target for specific treatments. [less ▲]Detailed reference viewed: 13 (2 ULg) Incorporation of iron and organic matter into young Antarctic sea ice during its initial growth stagesJanssens, Julie; Meiners, Klaus M.; Tison, Jean-Louis et alin Elementa: Science of the Anthropocene (2016), 4(1), 000123This study reports concentrations of iron (Fe) and organic matter in young Antarctic pack ice and during its initial growth stages in situ. Although the importance of sea ice as an Fe reservoir for ... [more ▼]This study reports concentrations of iron (Fe) and organic matter in young Antarctic pack ice and during its initial growth stages in situ. Although the importance of sea ice as an Fe reservoir for oceanic waters of the Southern Ocean has been clearly established, the processes leading to the enrichment of Fe in sea ice have yet to be investigated and quantified. We conducted two in situ sea-ice growth experiments during a winter cruise in the Weddell Sea. Our aim was to improve the understanding of the processes responsible for the accumulation of dissolved Fe (DFe) and particulate Fe (PFe) in sea ice, and of particulate organic carbon and nitrogen, dissolved organic carbon, extracellular polymeric substances, inorganic macro-nutrients (silicic acid, nitrate and nitrite, phosphate and ammonium), chlorophyll a and bacteria. Enrichment indices, calculated for natural young ice and ice newly formed in situ, indicate that during Antarctic winter all of the measured forms of particulate matter were enriched in sea ice compared to underlying seawater, and that enrichment started from the initial stages of sea-ice formation. Some dissolved material (DFe and ammonium) was also enriched in the ice but at lower enrichment indices than the particulate phase, suggesting that size is a key factor for the incorporation of impurities in sea ice. Low chlorophyll a concentrations and the fit of the macro-nutrients (with the exception of ammonium) with their theoretical dilution lines indicated low biological activity in the ice. From these and additional results we conclude that physical processes are the dominant mechanisms leading to the enrichment of DFe, PFe, organic matter and bacteria in young sea ice, and that PFe and DFe are decoupled during sea-ice formation. Our study thus provides unique quantitative insight into the initial incorporation of impurities, in particular DFe and PFe, into Antarctic sea ice. [less ▲]Detailed reference viewed: 24 (1 ULg) Model Sensitivity Studies of the Decrease in Atmospheric Carbon TetrachlorideChipperfield, M. P.; Liang, Q.; Rigby, M. et alin Atmospheric Chemistry & Physics Discussions (2016), 2016Carbon tetrachloride is an ozone-depleting substance, which is controlled by the Montreal Protocol and for which the atmospheric abundance is decreasing. However, the current observed rate of this ... [more ▼]Carbon tetrachloride is an ozone-depleting substance, which is controlled by the Montreal Protocol and for which the atmospheric abundance is decreasing. However, the current observed rate of this decrease is known to be slower than expected based on reported CCl4 emissions and its estimated overall atmospheric lifetime. Here we use a three-dimensional (3-D) chemical transport model to investigate the impact on its predicted decay of uncertainties in the rates at which CCl4 is removed from the atmosphere by photolysis, by ocean uptake and by degradation in soils. The largest sink is atmospheric photolysis (76% of total) but a reported 10% uncertainty in its combined photolysis cross-section and quantum yield has only a modest impact on the modelled rate of CCl4 decay. This is partly due to the limiting effect of the rate of transport of CCl4 from the main tropospheric reservoir to the stratosphere where photolytic loss occurs. The model suggests large interannual variability in the magnitude of this stratospheric photolysis sink caused by variations in transport. The impact of uncertainty in the minor soil sink (9% of total) is also relatively small. In contrast, the model shows that uncertainty in ocean loss (15% of total) has the largest impact on modelled CCl4 decay due to its sizeable contribution to CCl4 loss and large uncertainty range (157 to 313 years). With an assumed CCl4 emission rate of 39 Gg/yr, the reference simulation with best estimate of loss processes still underestimates the observed CCl4 (overestimates the decay) over the past two decades but to a smaller extent than previous studies. Changes to the rate of CCl4 loss processes, in line with known uncertainties, could bring the model into agreement with in situ surface and remote-sensing measurements, as could an increase in emissions to around 45 Gg/yr. Further progress in constraining the CCl4 budget is partly limited by systematic biases between observational datasets. For example, surface observations from the NOAA network are larger than from the AGAGE network but have shown a steeper decreasing trend over the past two decades. These differences imply a difference in emissions which is significant relative to uncertainties in the magnitudes of the CCl4 sinks. [less ▲]Detailed reference viewed: 27 (0 ULg) Use of slow-release plant infochemicals to control aphids: a first investigation in a Belgian wheat fieldZhou, Haibo; Chen, Longsheng; Liu, Yong et alin Scientific Reports (2016)Using infochemicals to develop a push–pull strategy in pest control is a potential way to promote sustainable crop production. Infochemicals from plant essential oils were mixed with paraffin oil for slow ... [more ▼]Using infochemicals to develop a push–pull strategy in pest control is a potential way to promote sustainable crop production. Infochemicals from plant essential oils were mixed with paraffin oil for slow release in field experiments on wheat to control the population density of cereal aphids and to enhance their natural enemies. (Z)-3-Hexenol (Z3H) attracted Metopolophum dirhodum and Sitobion avenae, the predominant species on wheat in Belgium, and may be a useful infochemical for aphid control by attracting aphids away from field plots. Release of (E)-β-farnesene (EBF) or a garlic extract (GE) led to a significant decrease in the abundance of wheat aphids. The main natural enemies of cereal aphids found were lacewings (47.8%), hoverflies (39.4%), and ladybirds (12.8%). Ladybird abundance varied little before the end of the wheat-growing season. Our results suggest that these chemicals can form the basis of a “push–pull” strategy for aphid biological control, with GE and EBF acting as a pestand beneficial-pulling stimulus and Z3H for aphid pulling. [less ▲]Detailed reference viewed: 26 (5 ULg) Émotion, ipséité, liberté. Réflexions à propos des fondements de la théorie sartrienne des émotionsRecchia, Fabio in Bulletin d'Analyse Phénoménologique (2016), 12(5), 1-23Entretenue durant la drôle de guerre, la correspondance épistolaire entre De Beauvoir et Sartre révèle une insatisfaction de ce dernier à l'égard de sa théorie des émotions. Celle-ci manquerait en effet ... [more ▼]Entretenue durant la drôle de guerre, la correspondance épistolaire entre De Beauvoir et Sartre révèle une insatisfaction de ce dernier à l'égard de sa théorie des émotions. Celle-ci manquerait en effet de fondements solides. Répondant à ce constat, nous tenterons de dégager les fondations de cette théorie de manière à expliciter ses enjeux. Nous replacerons, pour ce faire, l'Esquisse d'une théorie des émotions dans la perspective plus générale de la théorie de l'intentionnalité du premier Sartre. De la sorte nous montrerons, d'une part, comment ce texte renouvelle significativement la catégorie de l'action en concevant l'émotion comme une activité ; et nous examinerons, d'autre part, l'interaction existant entre l¿émotion et l'ipséité de la conscience. Cette discussion dévoilera ainsi l'intentionnalité émotive comme une passion active reconduisant au fondement de la conscience qui est sa liberté personnelle. [less ▲]Detailed reference viewed: 29 (7 ULg) Diagnostic Algorithm in the Management of Acute Febrile Abdomen in Patients with Autosomal Dominant Polycystic Kidney DiseaseNEUVILLE, Marie ; Hustinx, Roland ; JACQUES, Jessica et alin PLoS ONE (2016)Detailed reference viewed: 23 (2 ULg) A new global interior ocean mapped climatology: the 1° × 1° GLODAP version 2Lauvset, Siv K.; Key, Robert M.; Olsen, Are et alin Earth System Science Data (2016)Detailed reference viewed: 21 (1 ULg) Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7Szpakowska, Martyna; Dupuis, Nadine ; Baragli, Alessandra et alin Biochemical Pharmacology (2016), 114Detailed reference viewed: 23 (7 ULg) Ulcerative pododermatitis and disseminated erosive lesions associated with cowpox virus infection in a domestic catLudwig, Louisa ; Bohn, Jéromine ; Remy, Isabelle et alin Veterinary Record Case Reports (2016)The authors report on a case of feline cowpox virus infection associated with severe ulcerative dermatitis of a paw and disseminated erosive lesions. While the anamnesis of the cat being a known rodent ... [more ▼]The authors report on a case of feline cowpox virus infection associated with severe ulcerative dermatitis of a paw and disseminated erosive lesions. While the anamnesis of the cat being a known rodent-hunter, a typical seasonality of infection and the progression of clinical signs from a primary anterior lesion (forelimb) indicated a possible cowpox virus infection, the differential diagnosis was complicated by the resemblance of clinical signs to those induced by feline herpesvirus-dermatitis or feline calicivirus infection. These differential diagnoses were excluded by means of immunostaining and PCR, respectively. Detection of eosinophilic intracytoplasmic inclusion bodies in cells from biopsy material and positive PCR and sequencing results confirmed the diagnosis of cowpox virus infection. Genetic characterisation of the isolate, based on the highly diverse haemagglutinin gene, showed that the strain (Liege 2015; GenBank accession number: KU726584) clustered with other European isolates, mostly from exotic zoo animals. [less ▲]Detailed reference viewed: 17 (2 ULg) Characterization of stony soils' hydraulic conductivity using laboratory and numerical experimentsBeckers, Eléonore ; Pichault, Mathieu; Pansak, Wanwisa et alin SOIL (2016), 2Determining soil hydraulic properties is of major concern in various fields of study. Although stony soils are widespread across the globe, most studies deal with gravel-free soils, so that the literature ... [more ▼]Determining soil hydraulic properties is of major concern in various fields of study. Although stony soils are widespread across the globe, most studies deal with gravel-free soils, so that the literature describing the impact of stones on the hydraulic conductivity of a soil is still rather scarce. Most frequently, models characterizing the saturated hydraulic conductivity of stony soils assume that the only effect of rock fragments is to reduce the volume available for water flow, and therefore they predict a decrease in hydraulic conductivity with an increasing stoniness. The objective of this study is to assess the effect of rock fragments on the saturated and unsaturated hydraulic conductivity. This was done by means of laboratory experiments and numerical simulations involving different amounts and types of coarse fragments. We compared our results with values predicted by the aforementioned predictive models. Our study suggests that it might be ill-founded to consider that stones only reduce the volume available for water flow. We pointed out several factors of the saturated hydraulic conductivity of stony soils that are not considered by these models. On the one hand, the shape and the size of inclusions may substantially affect the hydraulic conductivity. On the other hand, laboratory experiments show that an increasing stone content can counteract and even overcome the effect of a reduced volume in some cases: we observed an increase in saturated hydraulic conductivity with volume of inclusions. These differences are mainly important near to saturation. However, comparison of results from predictive models and our experiments in unsaturated conditions shows that models and data agree on a decrease in hydraulic conductivity with stone content, even though the experimental conditions did not allow testing for stone contents higher than 20 %. [less ▲]Detailed reference viewed: 14 (3 ULg) Annual Greenland accumulation rates (2009–2012) from airborne snow radarKoenig, L.; Ivanoff, A.; Alexander, P. et alin Cryosphere (The) (2016), 10Contemporary climate warming over the Arctic is accelerating mass loss from the Greenland Ice Sheet through increasing surface melt, emphasizing the need to closely monitor its surface mass balance in ... [more ▼]Contemporary climate warming over the Arctic is accelerating mass loss from the Greenland Ice Sheet through increasing surface melt, emphasizing the need to closely monitor its surface mass balance in order to improve sea-level rise predictions. Snow accumulation is the largest component of the ice sheet's surface mass balance, but in situ observations thereof are inherently sparse and models are difficult to evaluate at large scales. Here, we quantify recent Greenland accumulation rates using ultra-wideband (2–6.5 GHz) airborne snow radar data collected as part of NASA's Operation IceBridge between 2009 and 2012. We use a semiautomated method to trace the observed radiostratigraphy and then derive annual net accumulation rates for 2009–2012. The uncertainty in these radar-derived accumulation rates is on average 14 %. A comparison of the radar-derived accumulation rates and contemporaneous ice cores shows that snow radar captures both the annual and long-term mean accumulation rate accurately. A comparison with outputs from a regional climate model (MAR) shows that this model matches radar-derived accumulation rates in the ice sheet interior but produces higher values over southeastern Greenland. Our results demonstrate that snow radar can efficiently and accurately map patterns of snow accumulation across an ice sheet and that it is valuable for evaluating the accuracy of surface mass balance models. [less ▲]Detailed reference viewed: 24 (0 ULg) Effectiveness of temporary implants in teenage patients: a prospective clinical trialLAMBERT, France ; BOTILDE, Gaëlle ; LECLOUX, Geoffrey et alin Clinical Oral Implants Research (2016)Abstract Aims: The objective of this study was to assess prospectively the outcomes of extra-narrow diameter implants (XNDI) placed in teenage patients as a temporary restorative option. Material and ... [more ▼]Abstract Aims: The objective of this study was to assess prospectively the outcomes of extra-narrow diameter implants (XNDI) placed in teenage patients as a temporary restorative option. Material and Methods: Twenty consecutive young patients presenting one or several missing teeth received XNDI that were immediately restored with composite, Polymethylmethacrylate (Acrylic) or ceramic crown. Clinical and radiographical outcomes were assessed for a minimum follow-up period of 1 year. Additionally, each patient completed retrospectively a satisfaction questionnaire using Visual Analog Scale (VAS). Results: A total of 30 implants were placed and followed for a period of 1–7.4 years (mean: 3.59 years). One implant failed after 3 weeks and was replaced successfully. No further biological complications occurred during the follow-up period, leading to an implant survival rate of 96.6%. The patient satisfaction evaluations displayed high levels of comfort and function. Conclusion: Immediately restored XNDI to replace missing teeth on teenager patients seems to be an effective temporary restorative option to replace missing teeth in young patients. Composite or ceramic crowns should be preferred. Clinical trials with long-term follow-ups and the assessment of passive egression are needed. [less ▲]Detailed reference viewed: 17 (3 ULg) Honey polyphenols extraction: method development and evidence of cis isomerizationIstasse, Thibaut ; Jacquet, Nicolas ; Berchem, Thomas et alin Analytical Chemistry Insights (2016), 11Honey polyphenols have been studied with the objective of relating honeys to their floral sources. Initially synthesized by plant, these polyphenols can be found in the plant’s nectar, where they are ... [more ▼]Honey polyphenols have been studied with the objective of relating honeys to their floral sources. Initially synthesized by plant, these polyphenols can be found in the plant’s nectar, where they are collected by bees which convert the nectar into honey. Consequently, polyphenols constitute minor honey components. The development of a solid phase extraction method for honey polyphenols is presented herein. The technique employs Amberlite XAD-2 adsorbent and was tested on monofloral honeys from six different plants: acacia, chestnut, eucalyptus, thyme, sunflower and wild carrot. Analyses were performed using high performance liquid chromatography coupled with UV detection and mass spectrometry. Several phenolic acids and flavonoids were identified: caffeic and p-coumaric acids, quercetin, kaempferol, naringenin, chrysin and pinocembrin. Generally, the quantity of a given polyphenol in the honey was around 0.2 mg/100g of honey, except for chestnut honey which contained around 3.0 mg of p-coumaric acid/100g of honey. Analyses highlighted significant formation of cis isomers for phenolic acids during the extraction despite protection from light. [less ▲]Detailed reference viewed: 30 (7 ULg) Ten years of atmospheric methane from ground-based NDACC FTIR observationsBader, Whitney ; Bovy, Benoît ; Conway, S. et alin Atmospheric Chemistry & Physics Discussions (2016), 2016Changes of atmospheric methane (CH4) since 2005 have been evaluated using Fourier Transform Infrared (FTIR) solar observations performed at ten ground-based sites, all members of the Network for Detection ... [more ▼]Changes of atmospheric methane (CH4) since 2005 have been evaluated using Fourier Transform Infrared (FTIR) solar observations performed at ten ground-based sites, all members of the Network for Detection of Atmospheric Composition Change (NDACC). From this, we find an increase of atmospheric methane total columns that amounts to 0.31 ± 0.03 % year-1 (2-sigma level of uncertainty) for the 2005–2014 period. Comparisons with in situ methane measurements at both local and global scales show good agreement. We used the GEOS-Chem Chemical Transport Model tagged simulation that accounts for the contribution of each emission source and one sink in the total methane, simulated over the 2005–2012 time period and based on emissions inventories and transport. After regridding according to NDACC vertical layering using a conservative regridding scheme and smoothing by convolving with respective FTIR seasonal averaging kernels, the GEOS-Chem simulation shows an increase of atmospheric methane of 0.35 ± 0.03 % year-1 between 2005 and 2012, which is in agreement with NDACC measurements over the same time period (0.30 ± 0.04 % year-1, averaged over ten stations). Analysis of the GEOS-Chem tagged simulation allows us to quantify the contribution of each tracer to the global methane change since 2005. We find that natural sources such as wetlands and biomass burning contribute to the inter-annual variability of methane. However, anthropogenic emissions such as coal mining, and gas and oil transport and exploration, which are mainly emitted in the Northern Hemisphere and act as secondary contributors to the global budget of methane, have played a major role in the increase of atmospheric methane observed since 2005. Based on the GEOS-Chem tagged simulation, we discuss possible cause(s) for the increase of methane since 2005, which is still unexplained. [less ▲]Detailed reference viewed: 35 (2 ULg) Greenland Ice sheet [in "State of the Climate in 2015"]Tedesco, M.; Box, J.; Cappelen, J. et alin Bulletin of the American Meteorological Society (2016), 97(8), The Greenland Ice Sheet, with the capacity to contribute ~7 m to sea level rise, experienced melting over more than 50% of its surface for the first time since the record melt of 2012.Detailed reference viewed: 11 (1 ULg) Intercomparison of in-situ NDIR and column FTIR measurements of CO2 at JungfraujochSchibig, M. F.; Mahieu, Emmanuel ; Henne, S. et alin Atmospheric Chemistry and Physics (2016), 16(15), 9935--9949We compare two CO2 time series measured at the High Alpine Research Station Jungfraujoch, Switzerland (3580 m a.s.l.), in the period from 2005 to 2013 with an in situ surface measurement system using a ... [more ▼]We compare two CO2 time series measured at the High Alpine Research Station Jungfraujoch, Switzerland (3580 m a.s.l.), in the period from 2005 to 2013 with an in situ surface measurement system using a nondispersive infrared analyzer (NDIR) and a ground-based remote sensing system using solar absorption Fourier transform infrared (FTIR) spectrometry. Although the two data sets show an absolute shift of about 13 ppm, the slopes of the annual CO2 increase are in good agreement within their uncertainties. They are 2.04±0.07 and 1.97±0.05 ppm yr-1 for the FTIR and the NDIR systems, respectively. The seasonality of the FTIR and the NDIR systems is 4.46±1.11 and 10.10±0.73 ppm, respectively. The difference is caused by a dampening of the CO2 signal with increasing altitude due to mixing processes. Whereas the minima of both data series occur in the middle of August, the maxima of the two data sets differ by about 10 weeks; the maximum of the FTIR measurements is in the middle of January, and the maximum of the NDIR measurements is found at the end of March. Sensitivity analyses revealed that the air masses measured by the NDIR system at the surface of Jungfraujoch are mainly influenced by central Europe, whereas the air masses measured by the FTIR system in the column above Jungfraujoch are influenced by regions as far west as the Caribbean and the USA. The correlation between the hourly averaged CO2 values of the NDIR system and the individual FTIR CO2 measurements is 0.820, which is very encouraging given the largely different sampling volumes. Further correlation analyses showed, that the correlation is mainly driven by the annual CO2 increase and to a lesser degree by the seasonality. Both systems are suitable to monitor the long-term CO2 increase, because this signal is represented in the whole atmosphere due to mixing. [less ▲]Detailed reference viewed: 48 (18 ULg) Major Changes in Growth Rate and Growth Variability of Beech (Fagus sylvatica L.) Related to Soil Alteration and Climate Change in BelgiumLatte, Nicolas ; Perin, Jérôme ; Kint, Vincent et alin Forests (2016), 7(174), Global change—particularly climate change, forest management, and atmospheric deposition—has significantly altered forest growing conditions in Europe. The influences of these changes on beech growth ... [more ▼]Global change—particularly climate change, forest management, and atmospheric deposition—has significantly altered forest growing conditions in Europe. The influences of these changes on beech growth (Fagus sylvatica L.) were investigated for the past 80 years in Belgium, using non-linear mixed effects models on ring-width chronologies of 149 mature and dominant beech trees (87–186 years old). The effects of the developmental stage (i.e., increasing tree size) were filtered out in order to focus on time-dependent growth changes. Beech radial growth was divided into a low-frequency signal (=growth rate), mainly influenced by forest management and atmospheric deposition, and into a high-frequency variability (≈mean sensitivity), mainly influenced by climate change. Between 1930 and 2008, major long-term and time-dependent changes were highlighted. The beech growth rate has decreased by about 38% since the 1950–1960s, and growth variability has increased by about 45% since the 1970–1980s. Our results indicate that (1) before the 1980s, beech growth rate was not predominantly impacted by climate change but rather by soil alteration (i.e., soil compaction and/or nitrogen deposition); and (2) since the 1980s, climate change induced more frequent and intense yearly growth reductions that amplified the growth rate decrease. The highlighted changes were similar in the two ecoregions of Belgium, although more pronounced in the lowlands than in the uplands. [less ▲]Detailed reference viewed: 13 (3 ULg) Incentives and barriers to environmental inequality mobilization: A case-study analysis in Wallonia, BelgiumLejeune, Zoé ; Teller, Jacques in Environmental Science and Policy (2016)Environmental inequality scholarship has sought to shed light on the unequal environmental conditions borne by poor people and racial minorities, and to challenge public policies. Most studies are ... [more ▼]Environmental inequality scholarship has sought to shed light on the unequal environmental conditions borne by poor people and racial minorities, and to challenge public policies. Most studies are concerned either with assessing the unequal distribution of environmental amenities and disamenities or with exploring the theoretical foundations of environmental justice movements. We propose an original approach to environmental inequality, focused not only on the unequal distribution of environmental burdens but also on two other types of factors: the capacity to mobilize and engage in community organizations on the one hand and the spatial dimension of environmental inequalities on the other. The evidence for this study is from an opinion survey carried out in 2012 with 1298 individuals. We use a two-step cluster analysis method to compute a classification system based on four categories of variables: socio-economic, environmental, spatial, and social capital. [less ▲]Detailed reference viewed: 28 (8 ULg) Estimating the economic impact of a possible equine and human epidemic of West Nile virus infection in BelgiumHumblet, Marie-France ; Vandeputte, Sébastien; Fecher-Bourgeois, Fabienne et alin Eurosurveillance (2016), 21(31), This study aimed at estimating, in a prospective scenario, the potential economic impact of a possible epidemic of WNV infection in Belgium, based on 2012 values for the equine and human health sectors ... [more ▼]This study aimed at estimating, in a prospective scenario, the potential economic impact of a possible epidemic of WNV infection in Belgium, based on 2012 values for the equine and human health sectors, in order to increase preparedness and help decision-makers. Modelling of risk areas, based on the habitat suitable for Culex pipiens, the main vector of the virus, allowed us to determine equine and human populations at risk. Characteristics of the different clinical forms of the disease based on past epidemics in Europe allowed morbidity among horses and humans to be estimated. The main costs for the equine sector were vaccination and replacement value of dead or euthanised horses. The choice of the vaccination strategy would have important consequences in terms of cost. Vaccination of the country’s whole population of horses, based on a worst-case scenario, would cost more than EUR 30 million; for areas at risk, the cost would be around EUR 16–17 million. Regarding the impact on human health, short-term costs and socio-economic losses were estimated for patients who developed the neuroinvasive form of the disease, as no vaccine is available yet for humans. Hospital charges of around EUR 3,600 for a case of West Nile neuroinvasive disease and EUR 4,500 for a case of acute flaccid paralysis would be the major financial consequence of an epidemic of West Nile virus infection in humans in Belgium. [less ▲]Detailed reference viewed: 19 (10 ULg) Assessment of the sea-ice carbon pump: Insights from a three-dimensional ocean-sea-ice biogeochemical model (NEMO-LIM-PISCES)Moreau, Sébastien; Vancoppenolle, Martin; Bopp, Laurent et alin Elementa: Science of the Anthropocene (2016), 4(1), 000122The role of sea ice in the carbon cycle is minimally represented in current Earth System Models (ESMs). Among potentially important flaws, mentioned by several authors and generally overlooked during ESM ... [more ▼]The role of sea ice in the carbon cycle is minimally represented in current Earth System Models (ESMs). Among potentially important flaws, mentioned by several authors and generally overlooked during ESM design, is the link between sea-ice growth and melt and oceanic dissolved inorganic carbon (DIC) and total alkalinity (TA). Here we investigate whether this link is indeed an important feature of the marine carbon cycle misrepresented in ESMs. We use an ocean general circulation model (NEMO-LIM-PISCES) with sea-ice and marine carbon cycle components, forced by atmospheric reanalyses, adding a first-order representation of DIC and TA storage and release in/from sea ice. Our results suggest that DIC rejection during sea-ice growth releases several hundred Tg C yr−1 to the surface ocean, of which < 2% is exported to depth, leading to a notable but weak redistribution of DIC towards deep polar basins. Active carbon processes (mainly CaCO3 precipitation but also ice-atmosphere CO2 fluxes and net community production) increasing the TA/DIC ratio in sea-ice modified ocean-atmosphere CO2 fluxes by a few Tg C yr−1 in the sea-ice zone, with specific hemispheric effects: DIC content of the Arctic basin decreased but DIC content of the Southern Ocean increased. For the global ocean, DIC content increased by 4 Tg C yr−1 or 2 Pg C after 500 years of model run. The simulated numbers are generally small compared to the present-day global ocean annual CO2 sink (2.6 ± 0.5 Pg C yr−1 ). However, sea-ice carbon processes seem important at regional scales as they act significantly on DIC redistribution within and outside polar basins. The efficiency of carbon export to depth depends on the representation of surface-subsurface exchanges and their relationship with sea ice, and could differ substantially if a higher resolution or different ocean model were used. [less ▲]Detailed reference viewed: 15 (2 ULg) Replacement of Glycoprotein B in Alcelaphine Herpesvirus 1 by Its Ovine Herpesvirus 2 Homolog : Implications in Vaccine Development for Sheep-Associated Malignant Catarrhal Fever.Cunha, Cristina W.; Taus, Naomi S.; Dewals, Benjamin G et alin mSphere (2016), 1(4), 00108-16Vaccine development is a top priority in malignant catarrhal fever (MCF) research. In the case of sheep-associated MCF (SA-MCF) caused by ovine herpesvirus 2 (OvHV-2), progress toward this objective has ... [more ▼]Vaccine development is a top priority in malignant catarrhal fever (MCF) research. In the case of sheep-associated MCF (SA-MCF) caused by ovine herpesvirus 2 (OvHV-2), progress toward this objective has been hindered by the absence of methods to attenuate or modify the virus, since it cannot be propagated in vitro. As an alternative for vaccine development, in this study, we tested the hypothesis that one of the SA-MCF vaccine candidate targets, OvHV-2 glycoprotein B (gB), could be expressed by a nonpathogenic alcelaphine herpesvirus 1 (AlHV-1) and then evaluated the potential of the AlHV-1/OvHV-2 chimera to be used as a vaccine and a diagnostic tool. The construction and characterization of an AlHV-1/OvHV-2 chimeric virus that is nonpathogenic and expresses an OvHV-2 vaccine target are significant steps toward the development of an SA-MCF vaccine and also provide a valuable means to study OvHV-2 biology. [less ▲]Detailed reference viewed: 16 (2 ULg) Parentification and related processes: distinction and implications for clinical practiceHaxhe, Stéphanie in Journal of Family Psychotherapy (2016), 27(3), 185-199With the emergence of what we call « new families », the place and the role of the child are increasingly questioned. If a child helps a parent or takes care of them, the terms “parentified child” ... [more ▼]With the emergence of what we call « new families », the place and the role of the child are increasingly questioned. If a child helps a parent or takes care of them, the terms “parentified child”, “parental child” or “adult child” are used equally. However, these concepts hide different processes that have different impacts on the child’s development. In the present article, based on our doctoral research and clinical practice experience, we will try to make the distinction between these concepts and to illustrate them. We are convinced that by a better identification of each process, we can help therapists and social workers in their interventions with children and their families. [less ▲]Detailed reference viewed: 38 (5 ULg) 2D-photochemical model for forbidden oxygen line emission for comet 1P/HalleyCessateur, G.; De Keyser, J.; Maggiolo, R. et alin Monthly Notices of the Royal Astronomical Society (2016)We present here a 2D-model of photochemistry for computing the production and loss mechanisms of the O([SUP]1[/SUP]S) and O([SUP]1[/SUP]D) states, which are responsible for the emission lines at 577.7 nm ... [more ▼]We present here a 2D-model of photochemistry for computing the production and loss mechanisms of the O([SUP]1[/SUP]S) and O([SUP]1[/SUP]D) states, which are responsible for the emission lines at 577.7 nm, 630 nm, and 636.4 nm, in case of the comet 1P/Halley. The presence of O[SUB]2[/SUB] within cometary atmospheres, measured by the in-situ ROSETTA and GIOTTO missions, necessitates a revision of the usual photochemical models. Indeed, the photodissociation of molecular oxygen also leads to a significant production of oxygen in excited electronic states. In order to correctly model the solar UV flux absorption, we consider here a 2D configuration. While the green to red-doublet ratio is not affected by the solar UV flux absorption, estimates of the red-doublet and green lines emissions are, however, overestimated by a factor of two in the 1D model compared to the 2D model. Considering a spherical symmetry, emission maps can be deduced from the 2D model in order to be directly compared to ground and/or in-situ observations. [less ▲]Detailed reference viewed: 8 (1 ULg) Realization of the Najafi-Golestanian microswimmerGrosjean, Galien ; Hubert, Maxime ; Lagubeau, Guillaume et alin Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2016), 94(2), 021101A paradigmatic microswimmer is the three-linked-spheres model, which follows a minimalist approach for propulsion by shape shifting. As such, it has been the subject of numerous analytical and numerical ... [more ▼]A paradigmatic microswimmer is the three-linked-spheres model, which follows a minimalist approach for propulsion by shape shifting. As such, it has been the subject of numerous analytical and numerical studies. In this Rapid Communication, an experimental three-linked-spheres swimmer is created by self-assembling ferromagnetic particles at an air-water interface. It is powered by a uniform oscillating magnetic field. A model, using two harmonic oscillators, reproduces the experimental findings. Because the model remains general, the same approach could be used to design a variety of efficient microswimmers. [less ▲]Detailed reference viewed: 11 (1 ULg) LOTUS: a low-cost, ultraviolet spectrographSteele, I. A.; Marchant, J. M.; Jermak, H. E. et alin Monthly Notices of the Royal Astronomical Society (2016), 460We describe the design, construction and commissioning of a simple, low-cost long-slit spectrograph for the Liverpool Telescope. The design is optimized for near-UV and visible wavelengths and uses all ... [more ▼]We describe the design, construction and commissioning of a simple, low-cost long-slit spectrograph for the Liverpool Telescope. The design is optimized for near-UV and visible wavelengths and uses all transmitting optics. It exploits the instrument focal plane field curvature to partially correct axial chromatic aberration. A stepped slit provides narrow (2.5 × 95 arcsec) and wide (5 × 25 arcsec) options that are optimized for spectral resolution and flux calibration, respectively. On sky testing shows a wavelength range of 3200-6300 Å with a peak system throughput (including detector quantum efficiency) of 15 per cent and wavelength dependent spectral resolution of R = 225-430. By repeated observations of the symbiotic emission line star AG Peg, we demonstrate the wavelength stability of the system is <2 Å rms and is limited by the positioning of the object in the slit. The spectrograph is now in routine operation monitoring the activity of comet 67P/Churyumov-Gerasimenko during its current post-perihelion apparition. [less ▲]Detailed reference viewed: 9 (0 ULg) The 19 Feb. 2016 Outburst of Comet 67P/CG: An ESA Rosetta Multi-Instrument StudyGrün, E.; Agarwal, J.; Altobelli, N. et alin Monthly Notices of the Royal Astronomical Society (2016)On 19 Feb. 2016 nine Rosetta instruments serendipitously observed an outburst of gas and dust from the nucleus of comet 67P/Churyumov-Gerasimenko. Among these instruments were cameras and spectrometers ... [more ▼]On 19 Feb. 2016 nine Rosetta instruments serendipitously observed an outburst of gas and dust from the nucleus of comet 67P/Churyumov-Gerasimenko. Among these instruments were cameras and spectrometers ranging from UV over visible to microwave wavelengths, in-situ gas, dust and plasma instruments, and one dust collector. At 9:40 a dust cloud developed at the edge of an image in the shadowed region of the nucleus. Over the next two hours the instruments recorded a signature of the outburst that significantly exceeded the background. The enhancement ranged from 50% of the neutral gas density at Rosetta to factors >100 of the brightness of the coma near the nucleus. Dust related phenomena (dust counts or brightness due to illuminated dust) showed the strongest enhancements (factors >10). However, even the electron density at Rosetta increased by a factor 3 and consequently the spacecraft potential changed from ˜-16 V to -20 V during the outburst. A clear sequence of events was observed at the distance of Rosetta (34 km from the nucleus): within 15 minutes the Star Tracker camera detected fast particles (˜25 m s[SUP]-1[/SUP]) while 100 μm radius particles were detected by the GIADA dust instrument ˜1 hour later at a speed of ~6 m s[SUP]-1[/SUP]. The slowest were individual mm to cm sized grains observed by the OSIRIS cameras. Although the outburst originated just outside the FOV of the instruments, the source region and the magnitude of the outburst could be determined. [less ▲]Detailed reference viewed: 12 (1 ULg) Biocompatibility of polymer-infiltrated-ceramic-network (PICN) materials with Human Gingival Fibroblasts (HGFs).GRENADE, Charlotte ; De Pauw-Gillet, Marie-Claire ; Gailly, Patrick et alin Dental materials : official publication of the Academy of Dental Materials (2016)OBJECTIVES: Polymer-infiltrated-ceramic-network (PICN) materials constitute an innovative class of CAD-CAM materials offering promising perspectives in prosthodontics, but no data are available in the ... [more ▼]OBJECTIVES: Polymer-infiltrated-ceramic-network (PICN) materials constitute an innovative class of CAD-CAM materials offering promising perspectives in prosthodontics, but no data are available in the literature regarding their biological properties. The objective of the present study was to evaluate the in vitro biocompatibility of PICNs with human gingival fibroblasts (HGFs) in comparison with materials typically used for implant prostheses and abutments. METHODS: HGF attachment, proliferation and spreading on discs made of PICN, grade V titanium (Ti), yttrium zirconia (Zi), lithium disilicate glass-ceramic (eM) and polytetrafluoroethylene (negative control), were evaluated using a specific insert-based culture system (IBS-R). Sample surface properties were characterized by XPS, contact angle measurement, profilometry and SEM. RESULTS: Ti and Zi gave the best results regarding HGF viability, morphology, number and coverage increase with time in comparison with the negative control, while PICN and eM gave intermediate results, cell spreading being comparable for PICN, Ti, Zi and eM. Despite the presence of polymers and their related hydrophobicity, PICN exhibited comparable results to glass-ceramic materials, which could be explained by the mode of polymerization of the monomers. SIGNIFICANCE: The results of the present study confirm that the currently employed materials, i.e. Ti and Zi, can be considered to be the gold standard of materials in terms of HGF behavior, while PICN gave intermediate results comparable to eM. The impact of the present in vitro results needs to be further investigated clinically, particularly in the view of the utilization of PICNs for prostheses on bone-level implants. [less ▲]Detailed reference viewed: 27 (2 ULg) Impact of vertical and horizontal advection on nutrient distribution in the southeast PacificBarceló-Llull, Barbara; Mason, Evan; Capet, Arthur et alin Ocean Science (2016), 12(4), 1003-1011An innovative approach is used to analyze the impact of vertical velocities associated with quasi-geostrophic (QG) dynamics on the redistribution and uptake of nitrate in the southeast Pacific (SEP). A ... [more ▼]An innovative approach is used to analyze the impact of vertical velocities associated with quasi-geostrophic (QG) dynamics on the redistribution and uptake of nitrate in the southeast Pacific (SEP). A total of 12 years of vertical and horizontal currents are derived from an observation based estimate of the ocean state. Horizontal velocities are obtained through the application of thermal wind balance to weekly temperature and salinity fields. Vertical velocities are estimated by integration of the QG omega equation. Seasonal variability of the synthetic vertical velocity and kinetic energy associated with the horizontal currents is coincident, with peaks in austral summer (November–December) in accord with published observations. The impact of vertical velocity on SEP nitrate uptake rates is assessed by using two Lagrangian particle tracking experiments that differ according to vertical forcing (ω = ωQG vs. ω = 0). From identical initial distributions of nitrate-tagged particles, the Lagrangian results show that vertical motions induce local increases in nitrate uptake reaching up to 30 %. Such increases occur in low uptake regions with high mesoscale activity. Despite being weaker than horizontal currents by a factor of up to 10−4, vertical velocity associated with mesoscale activity is demonstrated to make an important contribution to nitrate uptake, hence productivity, in low uptake regions. [less ▲]Detailed reference viewed: 23 (1 ULg) Forecasting travel behavior using Markov Chains-based approachesSaadi, Ismaïl ; El Saeid Mustafa, Ahmed Mohamed ; Teller, Jacques et alin Transportation Research. Part C : Emerging Technologies (2016), 69Recent advances in agent-based micro-simulation modeling have further highlighted the importance of a thorough full synthetic population procedure for guaranteeing the correct characterization of real ... [more ▼]Recent advances in agent-based micro-simulation modeling have further highlighted the importance of a thorough full synthetic population procedure for guaranteeing the correct characterization of real-world populations and underlying travel demands. In this regard, we propose an integrated approach including Markov Chain Monte Carlo (MCMC) simulation and profiling-based methods to capture the behavioral complexity and the great heterogeneity of agents of the true population through representative micro-samples. The population synthesis method is capable of building the joint distribution of a given population with its corresponding marginal distributions using either full or partial conditional probabilities or both of them simultaneously. In particular, the estimation of socio-demographic or transport-related variables and the characterization of daily activity-travel patterns are included within the framework. The fully probabilistic structure based on Markov Chains characterizing this framework makes it innovative compared to standard activity-based models. Moreover, data stemming from the 2010 Belgian Household Daily Travel Survey (BELDAM) are used to calibrate the modeling framework. We illustrate that this framework effectively captures the behavioral heterogeneity of travelers. Furthermore, we demonstrate that the proposed framework is adequately adapted to meeting the demand for large-scale micro-simulation scenarios of transportation and urban systems. [less ▲]Detailed reference viewed: 36 (5 ULg) Monitoring of anatabine release by methyl jasmonate elicited BY-2 cells using surface-enhanced Raman scatteringDe Bleye, Charlotte ; Dumont, Elodie ; Dispas, Amandine et alin Talanta (2016), 160A new application of surface-enhanced Raman scattering (SERS) in the field of plant material analysis is proposed in this study. The aim was to monitor the release of anatabine by methyl jasmonate (MeJa ... [more ▼]A new application of surface-enhanced Raman scattering (SERS) in the field of plant material analysis is proposed in this study. The aim was to monitor the release of anatabine by methyl jasmonate (MeJa) elicited Bright Yellow-2 (BY-2) cells. Gold nanoparticles (AuNps) were used as SERS substrate. The first step was to study the SERS activity of anatabine in a complex matrix comprising the culture medium and BY-2 cells. The second step was the calibration. This one was successfully performed directly in the culture medium in order to take into account the matrix effect, by spiking the medium with different concentrations of anatabine, leading to solutions ranging from 250 to 5000 µg L-1. A univariate analysis was performed, the intensity of a band situated at 1028 cm-1, related to anatabine, was plotted against the anatabine concentration. A linear relationship was observed with a R2 of 0.9951. During the monitoring study, after the MeJa elicitation, samples were collected from the culture medium containing BY-2 cells at 0, 24h, 48h, 72h and 96h and were analyzed using SERS. Finally, the amount of anatabine released in the culture medium was determined using the response function, reaching a plateau after 72h of 82 µg of anatabine released / g of fresh weight (FW) MeJa elicited BY-2 cells. [less ▲]Detailed reference viewed: 29 (9 ULg) PEGylation of lipoplexes: The right balance between cytotoxicity and siRNA effectivenessLechanteur, Anna ; Furst, Tania ; Evrard, Brigitte et alin European Journal of Pharmaceutical Sciences (2016), 93Detailed reference viewed: 10 (2 ULg) Downstream community impact lesson for future: case study of multipurpose Nam Mang 3 hydropower Project in Lao PDRKouangpalath, Phimthong ; Lebailly, Philippe ; Ducourtieux, Olivierin Sky Journal of Agricultural Research (2016), 5(6), 105-128Considering future projects, this paper examines the effects of hydropower dam projects on downstream communities. This study was conducted in the multi-purpose hydropower and irrigated areas of the Nam ... [more ▼]Considering future projects, this paper examines the effects of hydropower dam projects on downstream communities. This study was conducted in the multi-purpose hydropower and irrigated areas of the Nam Mang 3 Hydropower. Using a survey study with various stakeholders, household survey, several interviews were held with key informants in addition to field work observation. It was determined that this project has caused a number of negative impacts on farmers, especially those in downstream areas, directly reducing the water supply for agriculture and affecting the benefits from irrigation.. The main findings show that farmers are able to grow a second season of rice crops, but the electricity generated in the rainy season from the dam leads to the rice fields flooding along the downstream areas. [less ▲]Detailed reference viewed: 35 (10 ULg) Postmortem Internal Gas Reservoir Monitoring Using GCxGC-HRTOFMSStefanuto, Pierre-Hugues ; Perrault, Katelynn ; Grabher, Silke et alin separations (2016), 3(24), Forensic investigations often require postmortem examination of a body. However, the collection of evidence during autopsy is often destructive, meaning that the body can no longer be examined in its ... [more ▼]Forensic investigations often require postmortem examination of a body. However, the collection of evidence during autopsy is often destructive, meaning that the body can no longer be examined in its original state. In order to obtain an internal image of the body, whole body postmortem computed tomography (PMCT) has proven to be a valuable non-destructive tool and is currently used in medicolegal centers. PMCT can also be used to visually locate gas reservoirs inside a cadaver, which upon analysis can provide useful information regarding very volatile compounds that are produced after death. However, the non-targeted profiling of all potential volatile organic compounds (VOCs) present in these reservoirs has never been attempted. The aim of this study was to investigate the VOC profile of these reservoirs and to evaluate potential uses of such information to document circumstances surrounding death, cause of death and body taphonomy. Comprehensive two-dimensional gas chromatography coupled to time-of-flight high-resolution mass spectrometry (GC GC-HRTOF-MS) was used for VOC measurements. This study demonstrated that the chemical composition of VOCs within the gas reservoirs differed between locations within a single body but also between individuals. In the future, this work could be expanded to investigate a novel, non-destructive cadaver screening approach prior to full autopsy procedures. [less ▲]Detailed reference viewed: 15 (2 ULg) Amphibians breeding in refuge habitats have larvae with stronger antipredator responsesManenti, Raoul; Melotto, Andrea; Denoël, Mathieu et alin Animal Behaviour (2016), 118Antipredator responses are a key determinant of the successful persistence of prey, and behavioural modifications are a frequent antipredator strategy. However, conspecific populations often inhabit ... [more ▼]Antipredator responses are a key determinant of the successful persistence of prey, and behavioural modifications are a frequent antipredator strategy. However, conspecific populations often inhabit heterogeneous environments. This can determine local adaptations, and might also induce variation in antipredator responses. Nevertheless, there is limited information on whether heterogeneity of predation risk among populations determines variation in antipredator response. Here we studied the fire salamander, Salamandra salamandra, a species that can breed in both surface streams and caves, habitats that are predator-rich and predator-free, respectively, and measured differences in antipredator responses across populations with different predation risk. We combined field surveys and laboratory experiments to understand the role of predation risk on the activity patterns of larvae, while measuring behavioural differences between populations. We reared larvae from different habitats in safe and risky conditions and tested their response to predator cues before and after rearing. In the field, predation risk was much higher in surface streams than in caves; larvae moved more in the absence of predators and when the light intensity was low. During laboratory experiments, larvae were less active if reared in risky conditions, but cave larvae showed a stronger response to risk than stream larvae. Therefore, larvae from sites without predators showed higher antipredator responses than those from risky habitats. This response fits the predictions of the risk allocation model, in which prey from habitats with a high background level of risk need to be active even when predators are present, to satisfy their energetic demands. Our findings show that antipredator behaviour may differ strongly between populations and stress the importance of integrating this variability in studies on predatory responses. [less ▲]Detailed reference viewed: 23 (5 ULg) Interfascial spread of injectate after adductor canal injection in fresh human cadaversGOFFIN, Pierre ; LECOQ, Jean-Pierre ; NINANE, Vincent et alin Anesthesia and Analgesia (2016), 123(2), 501-503Detailed reference viewed: 14 (1 ULg) A general methodology for optimal load management with distributed renewable energy generation and storage in residential housingGeorges, Emeline ; Braun, James; Lemort, Vincent in Journal of Building Performance Simulation [=JBPS] (2016)In the US, buildings represent around 40% of the primary energy consumption and 74% of the electrical energy consumption [U.S. Department of Energy (DOE). 2012. 2011 Buildings Energy Data Book. Energy ... [more ▼]In the US, buildings represent around 40% of the primary energy consumption and 74% of the electrical energy consumption [U.S. Department of Energy (DOE). 2012. 2011 Buildings Energy Data Book. Energy Efficiency & Renewable Energy]. Incentives to promote the installation of on-site renewable energy sources have emerged in different states, including net metering programmes. The fast spread of such distributed power generation represents additional challenges for the management of the electricity grid and has led to increased interest in smart control of building loads and demand response programmes. This paper presents a general methodology for assessing opportunities associated with optimal load management in response to evolving utility incentives for residential buildings that employ renewable energy sources and energy storage. An optimal control problem is formulated for manipulating thermostatically controlled domestic loads and energy storage in response to the availability of renewable energy generation and utility net metering incentives. The methodology is demonstrated for a typical American house built in the 1990s and equipped with a single-speed air-to-air heat pump, an electric water heater and photovoltaic (PV) collectors. The additional potential associated with utilizing electrical batteries is also considered. Load matching performance for on-site renewable energy generation is characterized in terms of percentage of the electricity production consumed on-site and the proportion of the demand covered. For the purpose of assessing potential, simulations were performed assuming perfect predictions of the electrical load profiles. The method also allows determination of the optimal size of PV systems for a given net metering programme. Results of the case study showed significant benefits associated with control optimization including an increase of load matching between 3% and 28%, with the improvement dependent on the net metering tariff and available storage capacity. The estimated cost savings for the consumer ranged from 6.4% to 27.5% compared to no optimization with a unitary buy-back ratio, depending on the available storage capacity. Related reduction in CO2 emissions were between 11% and 46%. Optimal load management of the home thermal systems allowed an increase in the optimal size of the PV system in the range of 13–21%. [less ▲]Detailed reference viewed: 29 (7 ULg) Collaborative Care regarding major depressed patients: A review of guidelines and current practicesVan den Broeck, Kris; Remmen, Roy; Vanmeerbeek, Marc et alin Journal of Affective Disorders (2016), 200Major Depressive Disorder (MDD) is a severe and common mental disorder. A growing body of evidence suggests that stepped and/or collaborative care treatment models have several advantages for severely ... [more ▼]Major Depressive Disorder (MDD) is a severe and common mental disorder. A growing body of evidence suggests that stepped and/or collaborative care treatment models have several advantages for severely depressed patients and caretakers. However, despite the availability of these treatment strategies and guidance initiatives, many depressive patients are solely treated by the general practitioner (GP), and collaborative care is not common. In this paper, we review a selected set of international guidelines to inventory the best strategies for GPs and secondary mental health care providers to collaborate when treating depressed patients. Additionally, we systematically searched the literature, listing potential ways of cooperation, and potentially supporting tools. We conclude that the prevailing guidelines only include few and rather vague directions regarding the cooperation between GPs and specialised mental health practitioners. Inspiring recent studies, however, suggest that relatively little efforts may result in effective collaborative care and a broader implementation of the guidelines in general. [less ▲]Detailed reference viewed: 14 (3 ULg) Effects of aging on task- and stimulus-related cerebral attention networksKurth, Sophie ; Majerus, Steve ; Bastin, Christine et alin Neurobiology of Aging (2016), 44Interactions between a dorsal attention (DAN) and a ventral attention cerebral network (VAN) have been reported in young participants during attention or short term memory (STM) tasks. Since it remains an ... [more ▼]Interactions between a dorsal attention (DAN) and a ventral attention cerebral network (VAN) have been reported in young participants during attention or short term memory (STM) tasks. Since it remains an under-investigated question, age effects on DAN and VAN activity and their functional balance were explored during performance of a STM task. Older and young groups showed similar behavioral patterns of results. At the cerebral level, DAN activation increased as a function of increasing STM load in both groups, suggesting preserved activity in DAN during healthy aging. Age-related over-recruitment in regions of the DAN in the higher task load raised the question of compensation attempt versus less efficient use of neural resources in older adults. Lesser decrease of VAN activation with increasing load and decreased stimulus-driven activation in the VAN, especially in the higher load, in older participants suggested age-related reduced response in the VAN. However, functional connectivity measures showed that VAN was still functionally connected to the DAN in older participants. [less ▲]Detailed reference viewed: 48 (26 ULg) Hydrocarbon biostimulation and bioaugmentation in organic carbon and clay-rich soilsMasy, Thibaut ; Demanèche, Sandrine; Tromme, Olivier et alin Soil Biology & Biochemistry (2016), 99Hydrocarbon-contaminated organic carbon-rich clayey soils are challenging for bioremediation stakeholders since the pollutant is heterogeneously distributed and poorly bioavailable due to its strong ... [more ▼]Hydrocarbon-contaminated organic carbon-rich clayey soils are challenging for bioremediation stakeholders since the pollutant is heterogeneously distributed and poorly bioavailable due to its strong adsorption on clay and organic particles. In addition, biodegradation rates are restricted by limited diffusion of oxygen and nutrients to hydrocarbon-degrading aerobes. This study assessed the benefits of bioaugmentation with the strain Rhodococcus erythropolis T902.1 versus those from biostimulation and anaerobic natural attenuation in terms of hydrocarbon (HC) degradation efficiency and changes in the bacterial community structure in a diesel-polluted clay-rich soil. Three soil samples with a similar total organic content but with a different HC concentration (0.2, 1.0 and 6.5 g/kg) were compared in a microcosm experiment. Despite a limitation in oxygen transfer, R. erythropolis T902.1 enhanced a greater HC degradation compared to the biostimulation treatment. However, this advantage decreased with time as the proportion of Rhodococci declined from 25% initially to 1% of the global community after 80 days of treatment. Similarly, the alkB gene proportion in bioaugmented soils decreased to levels close to those of biostimulated soils. Consequently, further engineering was suggested to improve the resilience of the inoculum to ensure its long-term presence and activity in such polluted environments. [less ▲]Detailed reference viewed: 39 (7 ULg) Laser optics in space failure risk due to laser induced contaminationKokkinos, Dimitrios ; Schroeder, Helmut; Fleury-Frenette, Karl et alin CEAS Space Journal (2016), 8Detailed reference viewed: 21 (3 ULg) Longterm results of liver transplantation from donation after circulatory death.Blok, Joris J.; DETRY, Olivier ; Putter, Hein et alin Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society (2016), 22(8), 1107-14Donation after circulatory death (DCD) liver transplantation (LT) may imply a risk for decreased graft survival, caused by posttransplantation complications such as primary nonfunction or ischemic-type ... [more ▼]Donation after circulatory death (DCD) liver transplantation (LT) may imply a risk for decreased graft survival, caused by posttransplantation complications such as primary nonfunction or ischemic-type biliary lesions. However, similar survival rates for DCD and donation after brain death (DBD) LT have been reported. The objective of this study is to determine the longterm outcome of DCD LT in the Eurotransplant region corrected for the Eurotransplant donor risk index (ET-DRI). Transplants performed in Belgium and the Netherlands (January 1, 2003 to December 31, 2007) in adult recipients were included. Graft failure was defined as either the date of recipient death or retransplantation whichever occurred first (death-uncensored graft survival). Mean follow-up was 7.2 years. In total, 126 DCD and 1264 DBD LTs were performed. Kaplan-Meier survival analyses showed different graft survival for DBD and DCD at 1 year (77.7% versus 74.8%, respectively; P = 0.71), 5 years (65.6% versus 54.4%, respectively; P = 0.02), and 10 years (47.3% versus 44.2%, respectively; P = 0.55; log-rank P = 0.038). Although there was an overall significant difference, the survival curves almost reach each other after 10 years, which is most likely caused by other risk factors being less in DCD livers. Patient survival was not significantly different (P = 0.59). Multivariate Cox regression analysis showed a hazard ratio of 1.7 (P < 0.001) for DCD (corrected for ET-DRI and recipient factors). First warm ischemia time (WIT), which is the time from the end of circulation until aortic cold perfusion, over 25 minutes was associated with a lower graft survival in univariate analysis of all DCD transplants (P = 0.002). In conclusion, DCD LT has an increased risk for diminished graft survival compared to DBD. There was no significant difference in patient survival. DCD allografts with a first WIT > 25 minutes have an increased risk for a decrease in graft survival. Liver Transplantation 22 1107-1114 2016 AASLD. [less ▲]Detailed reference viewed: 12 (2 ULg) Horner syndrome in children: a clinical condition with serious underlying diseaseBarrea, Christophe ; Vigouroux, Tiphaine ; Karam, Joe et alin Neuropediatrics (2016), 47(4), 268-272Detailed reference viewed: 15 (1 ULg) Relationship between frailty, physical performance and quality of life among nursing home residents: the SENIOR cohortBuckinx, Fanny ; Reginster, Jean-Yves ; Petermans, Jean et alin Aging Clinical and Experimental Research (2016), Epub ahead of printBackground The aim of this study was to assess the relationship between frailty and a large number of indicators related to physical and muscular performance as well as quality of life. Methods This is an ... [more ▼]Background The aim of this study was to assess the relationship between frailty and a large number of indicators related to physical and muscular performance as well as quality of life. Methods This is an analysis of data collected at baseline in the Sample of Elderly Nursing home Individuals: an Observational Research (SENIOR) cohort including nursing home residents. Subjects are volunteer, oriented and able to walk (walking assistance allowed) nursing home residents in Belgium. A large number of demographic and clinical characteristics, including physical and muscular performance, were collected from each patient. The prevalence of frailty in this population was assessed using Fried’s definition. Results In total, 662 subjects are included in this analysis. The mean age of the sample is 83.2 ± 8.99 years, and 484 (73.1 %) are women. In this population of nursing home residents, the prevalence of frailty is 25.1 %, pre-frailty, 59.8 % and robustness, 15.1 %. Compared to non-frail subjects, frail subjects have lower physical and muscular performances and a lower quality of life. Conclusion Frailty, according to Fried’s definition, seems to be associated with several clinical indicators suggesting a higher level of disability and an increased propensity to develop major clinical consequences. Follow-up data of the SENIOR cohort will be helpful in confirming these findings, establishing cause–effect relationships and identifying the most predictive components of physical frailty for adverse outcomes in nursing homes. [less ▲]Detailed reference viewed: 8 (4 ULg) Guided group purchases of energy renovation services and works in deprived urban neighbourhoodsRuelle, Christine ; Teller, Jacques in Energy Efficiency (2016), 9(4), 861-874The energy retrofitting of housings is progressing very slowly in Wallonia (Belgium) despite individual fiscal measures and subsidies offered by public authorities to support households engaging in this ... [more ▼]The energy retrofitting of housings is progressing very slowly in Wallonia (Belgium) despite individual fiscal measures and subsidies offered by public authorities to support households engaging in this process. This paper explores the use of a method called ‘Guided Group Purchases’ (GPPs), i.e. an approach combining support, guidance and group purchasing of energy renovation services and works, as a possible method to accelerate the retrofitting of the existing housing stock. It reports on an action research experiment conducted in the context of the Interreg project ‘SUN’ (Sustainable Urban Neighbourhoods). The results of this experiment are quite promising. Within a few months, some 80 energy retrofitting interventions (energy audits or insulation works) were implemented in one neighbourhood of the city of Liège. Our evaluation of the experiment showed that the prospect of achieving cost reductions was one of the main initial expectations of participants to the GGPs. Still the participants rather insisted on other benefits after taking part to the initiative. These benefits were mostly related to the guidance they received, to the facilitation with contractors and to the social dynamics generated by the initiative. Several weaknesses were also identified by participants, like the lack of follow-up during and after the works. Our evaluation also highlighted that the main landlords did not participate in the initiative and that the influence of GGPs on costs was limited to specific types of interventions. Despite observed limitations and possible improvements, such a neighbourhood-based approach certainly constitutes a promising avenue for public authorities to support and accelerate the energy retrofitting of private residential buildings in urban neighbourhoods. [less ▲]Detailed reference viewed: 45 (15 ULg) Statistically Bundled Shewhart Control Charts for Monitoring Delivery Chains SystemsFoster, Earnest; Faraz, Alireza ; Heuchenne, Cédric in European Journal of Industrial Engineering (2016)Continuous monitoring of Delivery Time variables by means of control charts in a delivery chain is a very recent application of Statistical Process Control (SPC) to the service sector. The aim of the ... [more ▼]Continuous monitoring of Delivery Time variables by means of control charts in a delivery chain is a very recent application of Statistical Process Control (SPC) to the service sector. The aim of the proposed method is to provide supply chain decision makers with an easy to be managed tool monitoring the current functioning state of the delivery chain. The implementation of SPC control charts makes it possible to limit over-corrections to false alarm conditions and to maintain at an acceptable level the safety stock, with a consequent reduction of the overall management costs of the delivery chain. An illustrative example shows the proposed control chart implementation in a real delivery chain. [less ▲]Detailed reference viewed: 82 (2 ULg) Stable biofilms of Rhodococcus erythropolis T902.1 in draining pavement structures for runoff water decontaminationMasy, Thibaut ; Bertrand, Christelle ; Paul-Marie, Xavier et alin International Biodeterioration & Biodegradation (2016), 112Permeable Pavement Systems (PPS) are sustainable devices designed to collect, store and treat urban stormwater before its release into the ground. However, this system must sufficiently retain pollutants ... [more ▼]Permeable Pavement Systems (PPS) are sustainable devices designed to collect, store and treat urban stormwater before its release into the ground. However, this system must sufficiently retain pollutants brought by water runoff in order to comply with the current legislation. This study aims at evaluating the implementation in PPS of a hydrocarbonoclastic bacterium, Rhodococcus erythropolis T902.1, in terms of resilience and improvement of the degrading capacity. First results revealed that this strain could durably colonize the different gravels used in the construction of PPS. A 15-month experience in a real parking area showed that this biofilm remained viable without any replenishment of nutrients or bacteria. During accelerated pollution tests at a pilot scale, the structure bioaugmented with pre-coated biofilms was more efficient than a non-inoculated structure to limit hydrocarbon leaching below 50 μg L−1 and to degrade hydrocarbons adsorbed to the gravels. Over the long term, this innovative assembly should maintain the degrading capacity of PPS and ensure an effective treatment of stormwater before its infiltration into the soil. [less ▲]Detailed reference viewed: 26 (9 ULg) Les cuvettes oasiennes du Niger oriental: entre pratiques foncières et cadre législatifMalam Boukar, Awa Krou; Yamba, Boubacar; Andres, Ludovic et alin Revue Internationale des Sciences de Développement (2016), 4(6), 376-388Despite the new context of the land-law with the land committee, the property owner depends on the traditional law. This paper shows the land system in the south east of the Niger. Nine basin oasis have ... [more ▼]Despite the new context of the land-law with the land committee, the property owner depends on the traditional law. This paper shows the land system in the south east of the Niger. Nine basin oasis have selected in function of the food system and the proof of the phreatic table. An investigation with 105 producters has showed the description and the analysis of the land access and the conflicts. The analysis shows the strong influence of traditional authorities and the lack of operationalization of COFOB. Finally, the conflicts are generalized between many actors (farmers, pastoralists and agro-pastoralists) and settlement is done mainly by conciliation. Furthermore, the disparity between the men and the women land access is very important. [less ▲]Detailed reference viewed: 18 (5 ULg) High gene flow between alternative morphs and the evolutionary persistence of facultative paedomorphosisOromi Farrús, Neus ; Michaux, Johan ; Denoël, Mathieu in Scientific Reports (2016), 6Paedomorphosis and metamorphosis are two major developmental processes that characterize the evolution of complex life cycles in many lineages. Whereas these processes were fixed in some taxa, they ... [more ▼]Paedomorphosis and metamorphosis are two major developmental processes that characterize the evolution of complex life cycles in many lineages. Whereas these processes were fixed in some taxa, they remained facultative in others, with alternative phenotypes expressed in the same populations. From a genetic perspective, it is still unknown whether such phenotypes form a single population or whether they show some patterns of isolation in syntopy. This has deep implications for understanding the evolution of the phenotypes, i.e. towards their persistence or their fixation and speciation. Newts and salamanders are excellent models to test this hypothesis because they exhibit both developmental processes in their populations: the aquatic paedomorphs retain gills, whereas the metamorphs are able to colonize land. Using microsatellite data of coexisting paedomorphic and metamorphic palmate newts (Lissotriton helveticus), we found that they formed a panmictic population, which evidences sexual compatibility between the two phenotypes. The high gene flow could be understood as an adaptation to unstable habitats in which phenotypic plasticity is favored over the fixation of developmental alternatives. This makes then possible the persistence of a polyphenism: only metamorphosis could be maintained in case of occasional drying whereas paedomorphosis could offer specific advantages in organisms remaining in water. [less ▲]Detailed reference viewed: 19 (2 ULg) Automatic learning of fine operating rules for online power system security controlSun, Hongbin; Zhao, Feng; Wang, Huifang et alin IEEE Transactions on Neural networks and learning systems (2016), 27(8), 1708-1719Fine operating rules for security control and an automatic system for their online discovery were developed to adapt to the development of smart grids. The automatic system uses the real-time system state ... [more ▼]Fine operating rules for security control and an automatic system for their online discovery were developed to adapt to the development of smart grids. The automatic system uses the real-time system state to determine critical flowgates, and then a continuation power flow-based security analysis is used to compute the initial transfer capability of critical flowgates. Next, the system applies the Monte Carlo simulations to expected short-term operating condition changes, feature selection, and a linear least squares fitting of the fine operating rules. The proposed system was validated both on an academic test system and on a provincial power system in China. The results indicated that the derived rules provide accuracy and good interpretability and are suitable for real-time power system security control. The use of high-performance computing systems enables these fine operating rules to be refreshed online every 15 min. [less ▲]Detailed reference viewed: 55 (1 ULg) Release of cardiac biomarkers during a cycling raceLE GOFF, Caroline ; Kaux, Jean-François ; D'OTREPPE DE BOUVETTE, Stéphanie et alin World Journal of Cardiovascular Diseases (2016), 6(8), 285-294Objectives: Over the past two decades, a large interest in cardiac marker elevations has developed in endurance sports events. The intense effort is not without risk. We aim to see if the relatively ... [more ▼]Objectives: Over the past two decades, a large interest in cardiac marker elevations has developed in endurance sports events. The intense effort is not without risk. We aim to see if the relatively cardiospecific biomarkers could show the damage on cardiac muscle cells. Methods: Fourteen cyclists were recruited for an international race (177km). We studied the release of injury related cardiac markers, risk related cardiac markers, renal function markers and blood cytology. The subjects were submitted to three blood test: one before (T0), one just after (T1) and the last one 3 hours after the race (T3). Results: Blood cytology markers, namely erythrocytes, hemoglobin, hematocrit, and average hemoglobin concentration, were found to evolve in a similar way. Renal function markers, such as creatinin, cystatin C and uric acid, showed a post effort increase that might be related to renal blood flow depletion during exercise. Cardiac and muscular markers were all increased at T1. Conclusions: Physiological stress induced by an international cycling race certainly has consequences on cardiac muscle cells. Fortunately, those blood concentration variations are more representative of a transitional state, due to an imbalance created by an intense aerobic effort maintained during several hours, rather than an irreversible injury. [less ▲]Detailed reference viewed: 9 (2 ULg) Calcium-Iron Oxide as Energy Storage Medium in Rechargeable Oxide BatteriesBerger, Cornelius M.; Mahmoud, Abdelfattah ; Hermann, Raphaël et alin Journal of the American Ceramic Society (2016)Rechargeable oxide batteries (ROB) comprise a regenerative solid oxide cell (rSOC) and a storage medium for oxygen ions. A sealed ROB avoids pumping loss, heat loss, and gas purity expenses in comparison ... [more ▼]Rechargeable oxide batteries (ROB) comprise a regenerative solid oxide cell (rSOC) and a storage medium for oxygen ions. A sealed ROB avoids pumping loss, heat loss, and gas purity expenses in comparison with conventional rSOC. However, the iron oxide base storage medium degrades during charging– discharging cycles. In comparison, CaFe3O5 has improved cyclability and a high reversible oxygen storage capacity of 22.3 mol%. In this study, we analyzed the redox mechanism of this compound. After a solid-state synthesis of CaFe3O5, we verified the phase composition and studied the redox reaction by means of X-ray diffraction, Mossbauer spectrometry, and scanning electron microscopy. Results show a great potential to operate the battery with this storage material during multiple charging–discharging cycles. [less ▲]Detailed reference viewed: 9 (2 ULg) Du côté de chez...Godefroid Kurth. Réflexions personnellesGenin, Vincent in Bulletin Trimestriel de l'Institut Archéologique du Luxembourg Arlon (2016), 92(3/4), 99-107Detailed reference viewed: 10 (0 ULg) Local modulation of human brain responses by circadian rhythmicity and sleep debtMuto, Vincenzo ; Jaspar, Mathieu ; Meyer, Christelle et alin Science (2016), 351(6300), Detailed reference viewed: 19 (5 ULg) High selfing rate, limited pollen dispersal and inbreeding depression in the emblematic African rain forest tree Baillonella toxisperma - Management implicationsDuminil, Jérôme; Mendene Abessolo, D. T.; Ndiade Bourobou, D. et alin Forest Ecology & Management (2016), 379Mating system and gene flow are major influencing factors of species population dynamics and evolution. These factors are often not characterized in tropical tree species, yet they constitute basic ... [more ▼]Mating system and gene flow are major influencing factors of species population dynamics and evolution. These factors are often not characterized in tropical tree species, yet they constitute basic information that must be considered to implement sustainable management practices. In particular, as logging implies a reduction of the density of congeneric mates, the connectivity through pollination between individuals has to be well characterized (selfing versus outcrossing rates, distances between mates). We conducted a genetic-based analysis (using 10 nuclear microsatellites) to determine the mating system and gene flow characteristics of an emblematic timber tree species from lowland rain forests of the Congo Basin, Baillonella toxisperma (Sapotaceae). The species, which is frequently exploited for its wood and for a number of non-timber forest products, naturally occurs at low densities (ca. 0.01–0.1 individuals/ha). It is supposedly an entomophilous species whose seeds are probably dispersed by mammals. We have shown that the species presents a mixed-mating system (about 20–40% of selfing depending on analysis method). However, the comparison of inbreeding parameters among cohorts suggests that inbred individuals die between seedling and mature tree stages. The mean pollen dispersal distance was relatively low for such a low-density population species (estimated to be 690 or 777 m depending on analysis method) and, together with a low mean number of pollen donors (NEP = 2.76), it suggests a pattern of nearest-neighbour mating where allo-pollen could be a limiting factor. However, B. toxisperma presents a relatively weak genetic structure (Sp statistic = 0.0095) indicative of long gene dispersal distance (rg = 3–5 km according to the assumed effective population density). Overall, this would indicate that gene flow occurs mainly by extensive seed dispersal in this species. These results suggest that mammals and local populations involved in the dispersal of the species play a key role by lowering biparental inbreeding effects. Sustainable population management might require assisted regeneration using unrelated planting material. [less ▲]Detailed reference viewed: 15 (3 ULg) Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).Bousquet, J.; Farrell, J.; Crooks, G. et alin Clinical and translational allergy (2016), 6Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic ... [more ▼]Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing. [less ▲]Detailed reference viewed: 8 (1 ULg) Fruit biomass availability along a forest cover gradiantPessoa; Rocca, Larissa; Talora, Daniela et alin Biotropica (2016)Habitat loss is the main driver of the current high rate of species extinction, particularly in tropical forests. Understanding the factors associated with biodiversity loss, such as the extinction of ... [more ▼]Habitat loss is the main driver of the current high rate of species extinction, particularly in tropical forests. Understanding the factors associated with biodiversity loss, such as the extinction of species interactions and ecological functions, is an urgent priority. Here, our aim was to evaluate how landscape-scale forest cover influences fruit biomass comparing different tree functional groups. We sampled 20 forest fragments located within landscapes with forest cover ranging from 2 to 93 percent in the Atlantic Forest of southern Bahia, Brazil. In each fragment, we established five plots of 25 × 4 m and carried out phenological observations on fleshy fruit throughout one year on all trees ≥ 5 cm dbh. We estimated fruit availability by direct counting all fruits and derived fruit biomass from this count. We used spatial mixed linear models to evaluate the effects of forest cover on species richness, abundance, and fruit biomass. Our results indicated that forest cover was the main explanatory variable and negatively influenced the total richness and abundance of zoochoric and shade-tolerant but not shade-intolerant species. A linear model best explained variations in richness and abundance of total and shade-tolerant species. We also found that forest cover was positively correlated with the fruit biomass produced by all species and by the shade-tolerant assemblages, with linear models best explaining both relationships. The loss of shade-tolerant species and the lower fruit production in fragments with lower landscape-scale forest cover may have implications for the maintenance of frugivore, seed dispersal service, and plant recruitment. [less ▲]Detailed reference viewed: 31 (1 ULg) The Future of National Data Retention Obligations – How to Apply Digital Rights Ireland at National LevelFranssen, Vanessa in European Law Blog (2016)Detailed reference viewed: 14 (1 ULg) Apports phénoménologiques à l’étude de la relation au corps dans le jeu vidéoDelbouille, Julie in Implications philosophiques (2016)J’évite un obstacle. Je cours. Je saute. Alors que quelques notes de musique m’avertissent de l’échec de ce dernier mouvement, je vois mon corps chuter, happé par le vide au-delà de l’écran. Cette scène ... [more ▼]J’évite un obstacle. Je cours. Je saute. Alors que quelques notes de musique m’avertissent de l’échec de ce dernier mouvement, je vois mon corps chuter, happé par le vide au-delà de l’écran. Cette scène, qui tout comme ses multiples variations s’inscrit en filigrane au cœur de nombreuses expériences vidéoludiques, soulève la question du rapport au corps dans le jeu vidéo. Dans le champ des Game et des Play Studies, nombreux sont les chercheurs qui se sont déjà emparés de l’interactivité comme objet d’étude, et d’une de ses modalités dans le jeu vidéo : l’avatar. Interface récurrente entre le joueur et l’univers vidéoludique, nous postulons que cette « enveloppe pilotable » constitue une porte d’entrée pour envisager la problématique corporelle dans le jeu vidéo. En effet, la fonction d’incarnation permise par l’avatar ajoute à la relation entre le corps et l’esprit du joueur une dimension nouvelle : celle du corps virtuel. Ce corps « autre », dont le joueur prend possession, constitue une des conditions de son « insertion » dans le monde du jeu. [less ▲]Detailed reference viewed: 24 (2 ULg) Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.Plissonneau; Pansieri, Jonathan; Heinrich-Balard, L et alin Journal of Nanobiotechnology (2016), 14(1), 10118612951-016-0212-Detailed reference viewed: 13 (1 ULg) DEM modeling of ball mills with experimental validation: influence of contact parameters on charge motion and power drawBoemer, Dominik ; Ponthot, Jean-Philippe in Computational Particle Mechanics (2016)Discrete element method simulations of a 1:5-scale laboratory ball mill are presented in this paper to study the influence of the contact parameters on the charge motion and the power draw. The position ... [more ▼]Discrete element method simulations of a 1:5-scale laboratory ball mill are presented in this paper to study the influence of the contact parameters on the charge motion and the power draw. The position density limit is introduced as an efficient mathematical tool to describe and to compare the macroscopic charge motion in different scenarios, i.a. with different values of the contact parameters. While the charge motion and the power draw are relatively insensitive to the stiffness and the damping coefficient of the linear spring-slider-damper contact law, the coefficient of friction has a strong influence since it controls the sliding propensity of the charge. Based on the experimental calibration and validation by charge motion photographs and power draw measurements, the descriptive and predictive capabilities of the position density limit and the discrete element method are demonstrated, i.e. the real position of the charge is precisely delimited by the respective position density limit and the power draw can be predicted with an accuracy of about 5 %. [less ▲]Detailed reference viewed: 23 (10 ULg) Epiphytic bryozoans on Neptune grass – a sample-based data setLepoint, Gilles ; Heughebaert, André; Michel, Loïc in ZooKeys (2016), 606Background The seagrass Posidonia oceanica L. Delile, commonly known as Neptune grass, is an endemic species of the Mediterranean Sea. It hosts a distinctive and diverse epiphytic community, dominated by ... [more ▼]Background The seagrass Posidonia oceanica L. Delile, commonly known as Neptune grass, is an endemic species of the Mediterranean Sea. It hosts a distinctive and diverse epiphytic community, dominated by various macroalgal and animal organisms. Mediterranean bryozoans have been extensively studied but quantitative data assessing temporal and spatial variability have rarely been documented. In Lepoint et al. (2014a, b) occurrence and abundance data of epiphytic bryozoan communities on leaves of P. oceanica inhabiting the Revellata Bay (Corsica, Mediterranean Sea) were reported and trophic ecology of Electra posidoniae Gautier assessed. New information Here, we provide metadata information on data set discussed in Lepoint et al. 2014a and published on the GBIF portal as a sampling-event data set: http://ipt.biodiversity.be/resource?r=ulg_bryozoa&v=1.0). The data set, compared to Lepoint et al. 2014a, is enriched by data concerning species settled on Posidonia scales (dead petiole of Posidonia leaves, remaining after limb abscission). [less ▲]Detailed reference viewed: 40 (8 ULg) HCOOH distributions from IASI for 2008-2014: comparison with ground-based FTIR measurements and a global chemistry-transport modelPommier, M.; Clerbaux, C.; Coheur, P.-F. et alin Atmospheric Chemistry and Physics (2016), 16Formic acid (HCOOH) is one of the most abundant volatile organic compounds in the atmosphere. It is a major contributor to rain acidity in remote areas. There are, however, large uncertainties on the ... [more ▼]Formic acid (HCOOH) is one of the most abundant volatile organic compounds in the atmosphere. It is a major contributor to rain acidity in remote areas. There are, however, large uncertainties on the sources and sinks of HCOOH and therefore HCOOH is misrepresented by global chemistry-transport models. This work presents global distributions from 2008 to 2014 as derived from the measurements of the Infrared Atmospheric Sounding Interferometer (IASI), based on conversion factors between brightness temperature differences and representative retrieved total columns over seven regions: Northern Africa, southern Africa, Amazonia, Atlantic, Australia, Pacific, and Russia. The dependence of the measured HCOOH signal on the thermal contrast is taken into account in the conversion method. This conversion presents errors lower than 20 % for total columns ranging between 0.5 and 1 × 1016 molec/cm2 but reaches higher values, up to 78 %, for columns that are lower than 0.3 × 1016 molec/cm2. Signatures from biomass burning events are highlighted, such as in the Southern Hemisphere and in Russia, as well as biogenic emission sources, e.g., over the eastern USA. A comparison between 2008 and 2014 with ground-based Fourier transform infrared spectroscopy (FTIR) measurements obtained at four locations (Maido and Saint-Denis at La Réunion, Jungfraujoch, and Wollongong) is shown. Although IASI columns are found to correlate well with FTIR data, a large bias (> 100 %) is found over the two sites at La Réunion. A better agreement is found at Wollongong with a negligible bias. The comparison also highlights the difficulty of retrieving total columns from IASI measurements over mountainous regions such as Jungfraujoch. A comparison of the retrieved columns with the global chemistry-transport model IMAGESv2 is also presented, showing good representation of the seasonal and interannual cycles over America, Australia, Asia, and Siberia. A global model underestimation of the distribution and a misrepresentation of the seasonal cycle over India are also found. A small positive trend in the IASI columns is observed over Australia, Amazonia, and India over the 2008–2014 period (from 0.7 to 1.5 %/year), while a decrease of ∼ 0.8 %/year is measured over Siberia. [less ▲]Detailed reference viewed: 29 (4 ULg) La biodiversité entomologique comme source d’aliments à Kinshasa (République démocratique du Congo)Nsevolo, Papy; Alabi, Taofic ; Caparros Megido, Rudy et alin Annales de la Société Entomologique de France (2016)L’exploitation des produits forestiers non ligneux dont notamment les insectes comestibles jouent un rôle important dans les habitudes alimentaires et économies locales des populations autochtones du ... [more ▼]L’exploitation des produits forestiers non ligneux dont notamment les insectes comestibles jouent un rôle important dans les habitudes alimentaires et économies locales des populations autochtones du bassin du Congo. Bien que la consommation d’insectes en République Démocratique du Congo soit une pratique ancienne, l’inventaire et l’identification taxonomique des espèces consommées ainsi que la caractérisation de la filière « entomophagie » sont encore mal maitrisés. Toutefois, nos études axées sur la ville de Kinshasa ont permis d’inventorier 14 espèces comestibles régulièrement consommées. Elles appartiennent à l’ordre des Lépidoptères (46,7%), des Isoptères (18,6%), des Orthoptères (17,6%), des Coléoptères (9,7%) et des Hyménoptères (3,7%). De façon générale, 80% de la population de Kinshasa consomment au minimum une espèce d’insecte 5 jours par mois avec des quantités variant de 66,4 à 154 g d’insectes par personne par jour en fonction des différents ordres. Les acteurs de la filière sont majoritairement des femmes. Les revenus générés par l’activité concourent au bien-être des ménages, à la réduction de la pauvreté et de l’insécurité alimentaire dans de la capitale Kinshasa. [less ▲]Detailed reference viewed: 18 (6 ULg) First characterization and validation of FORLI-HNO3 vertical profiles retrieved from IASI/MetopRonsmans, G.; Langerock, B.; Wespes, C. et alin Atmospheric Measurement Techniques. Papers in Open Discussion (2016), 2016Knowing the spatial and seasonal distributions of nitric acid (HNO3) around the globe is of great interest to apprehend the processes regulating stratospheric ozone, especially in the polar regions ... [more ▼]Knowing the spatial and seasonal distributions of nitric acid (HNO3) around the globe is of great interest to apprehend the processes regulating stratospheric ozone, especially in the polar regions. Thanks to its unprecedented spatial and temporal sampling, the nadir-viewing Infrared Atmospheric Sounding Interferometer (IASI) allows sounding the atmosphere twice a day globally, with good spectral resolution and low noise. With the Fast Optimal Retrievals on Layers for IASI (FORLI) algorithm, we are retrieving, in near-real time, columns as well as vertical profiles of several atmospheric species, amongst which is HNO3. We present in this paper the first characterization of the FORLI-HNO3 profile products, in terms of vertical sensitivity and error budgets. We show that the sensitivity of IASI to HNO3 is highest in the lower stratosphere (10–20km), where the largest amounts of HNO3 are found, but that the vertical sensitivity of IASI only allows one level of information on the profile (DOFS 1). The sensitivity near the surface is negligible in most cases, and for this reason, a partial column (5–35km) is used for the analyses. Both vertical profiles and partial columns are compared to FTIR ground-based measurements from the Network for the Detection of Atmospheric Composition Change (NDACC) to characterize the accuracy and precision of the FORLI-HNO3 product. The profile validation is conducted through the smoothing of the raw FTIR profiles by the IASI averaging kernels and gives good results, with a slight overestimation of IASI measurements in the Upper Troposphere-Lower Stratosphere (UTLS) at the 6 chosen stations (Thule, Kiruna, Jungfraujoch, Izaña, Lauder and Arrival Heights). The validation of the partial columns (5–35km) is also conclusive with a mean correlation of 0.93 between IASI and the FTIR measurements. An initial survey of the HNO3 spatial and seasonal variabilities obtained from IASI measurements for a one year (2011) data set shows that the expected latitudinal gradient of concentrations from low to high latitudes and the large seasonal variability in polar regions (cycle amplitude around 30% of the seasonal signal, peak-to-peak) are well represented with IASI data. [less ▲]Detailed reference viewed: 25 (1 ULg) Azacytidine mitigates experimental sclerodermic graft-versus-host diseaseFransolet, Gilles ; Ehx, Grégory ; SOMJA, Joan et alin Journal of Hematology & Oncology (2016)Background Previous studies have demonstrated that regulatory T cells (Tregs) play a protective role in the pathogenesis of chronic graft-versus-host disease (cGVHD). Tregs constitutively express the gene ... [more ▼]Background Previous studies have demonstrated that regulatory T cells (Tregs) play a protective role in the pathogenesis of chronic graft-versus-host disease (cGVHD). Tregs constitutively express the gene of the transcription factor Foxp3 whose CNS2 region is heavily methylated in conventional CD4+ T cells (CD4+Tconvs) but demethylated in Tregs. Methods Here, we assessed the impact of azacytidine (AZA) on cGVHD in a well-established murine model of sclerodermic cGVHD (B10.D2 (H-2d) → BALB/cJ (H-2d)). Results The administration of AZA every 48 h from day +10 to day +30 at the dose of 0.5 mg/kg or 2 mg/kg mitigated chronic GVHD. Further, AZA-treated mice exhibited higher blood and thymic Treg frequencies on day +35, as well as higher demethylation levels of the Foxp3 enhancer and the IL-2 promoter in splenocytes at day +52. Interestingly, Tregs from AZA-treated mice expressed more frequently the activation marker CD103 on day +52. AZA-treated mice had also lower counts of CD4+Tconvs and CD8+ T cells from day +21 to day +35 after transplantation, as well as a lower proportion of CD4+Tconvs expressing the Ki67 antigen on day +21 demonstrating an anti-proliferating effect of the drug on T cells. Conclusions Our results indicate that AZA prevented sclerodermic cGVHD in a well-established murine model of cGVHD. These data might serve as the basis for a pilot study of AZA administration for cGVHD prevention in patients at high risk for cGVHD. [less ▲]Detailed reference viewed: 30 (16 ULg) Démographie et performances zootechniques des élevages bovins traditionnels au Nord BéninChabi Toko, Roukayath ; Adégbidi, Anselme; Lebailly, Philippe in Revue d'Elévage et de Médecine Vétérinaire des Pays Tropicaux (2016), 69(1), 33-39The study was conducted with 150 Fulani herders in the departments of Borgu and Alibori in Benin. It aimed to determine the zootechnical parameters of traditional cattle farms. The survey collected ... [more ▼]The study was conducted with 150 Fulani herders in the departments of Borgu and Alibori in Benin. It aimed to determine the zootechnical parameters of traditional cattle farms. The survey collected information on the characteristics of cattle herds. The results showed a high proportion of females (76%), an average herd size (66 animals) and the prevalence of the Borgu breed (86%). The herds also showed a low breeding performance, characterized by a high calf mortality rate (10%), and low reproductive parameters (64% calving and fertility rates). In a year, 0.57 calf was weaned on average by its dam. The low performance of cattle farms in coastal countries such as Benin is consistent with that of pastoral areas, which is complementary in terms of meat supply to West African markets. [less ▲]Detailed reference viewed: 27 (2 ULg) Asymptotic properties of free monoid morphismsCharlier, Emilie ; Leroy, Julien ; Rigo, Michel in Linear Algebra & its Applications (2016), 500Detailed reference viewed: 20 (9 ULg) Le sexe ratio chez les bovins : facteurs de variationHanzen, Christian ; Chastant-Maillard, Sylvie; Rao, Anne-Sophie et alin Point Vétérinaire (Le) : Expert Rural (2016), 367Le sexe ratio secondaire, défini comme la proportion de mâles à la naissance, est de 52% chez les bovins, avec des variations selon les populations étudiées de 46 à 57%. Il est plus élevé lors des ... [more ▼]Le sexe ratio secondaire, défini comme la proportion de mâles à la naissance, est de 52% chez les bovins, avec des variations selon les populations étudiées de 46 à 57%. Il est plus élevé lors des premières étapes du développement embryonnaire, et les conceptus mâles meurent proportionnellement plus au cours de la gestation que les conceptus femelles. Les facteurs de variation potentiels sont nombreux, mais peu d’effets sont unanimement observés. L’effet de la parité ou du statut social de la vache ne sont pas clairement démontrés. Les ovulations sur l’ovaire droit donneraient naissance à une plus forte proportion de mâles ; le rôle du taureau est probablement limité et la répétabilité du sexe du veau d’une gestation à l’autre est faible. Le moment de l’insémination par rapport à l’ovulation ne semble pas avoir d’influence alors qu’il aurait pu constituer un moyen de maîtrise assez simple à mettre en œuvre. [less ▲]Detailed reference viewed: 18 (1 ULg)