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See detailUn type picard par-delà les frontières : le <nom jeté>
Baiwir, Esther ULg

in Dialectes de Wallonie (in press), 36

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See detailHuman herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7
Szpakowska, Martyna; Dupuis, Nadine ULg; Baragli, Alessandra et al

in Biochemical Pharmacology (in press)

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See detailA combined transmission spectrum of the Earth-sized exoplanets TRAPPIST-1 b and c
de Wit, Julien; Wakeford, Hannah R.; Gillon, Michaël ULg et al

in Nature (in press)

Three Earth-sized exoplanets were recently discovered close to the habitable zone of the nearby ultracool dwarf star TRAPPIST-1. The nature of these planets has yet to be determined, since their masses ... [more ▼]

Three Earth-sized exoplanets were recently discovered close to the habitable zone of the nearby ultracool dwarf star TRAPPIST-1. The nature of these planets has yet to be determined, since their masses remain unmeasured and no observational constraint is available for the planetary population surrounding ultracool dwarfs, of which the TRAPPIST-1 planets are the first transiting example. Theoretical predictions span the entire atmospheric range from depleted to extended hydrogen-dominated atmospheres. Here, we report a space-based measurement of the combined transmission spectrum of the two inner planets made possible by a favorable alignment resulting in their simultaneous transits on 04 May 2016. The lack of features in the combined spectrum rules out cloud-free hydrogen-dominated atmospheres for each planet at 10-$\sigma$ levels; TRAPPIST-1 b and c are hence unlikely to harbor an extended gas envelope as they lie in a region of parameter space where high-altitude cloud/haze formation is not expected to be significant for hydrogen-dominated atmospheres. Many denser atmospheres remain consistent with the featureless transmission spectrum---from a cloud-free water vapour atmosphere to a Venus-like atmosphere. [less ▲]

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See detailCo-simulation of Electromagnetic Transients and Phasor Models: a Relaxation Approach
Plumier, Frédéric ULg; Aristidou, Petros; Geuzaine, Christophe ULg et al

in IEEE Transactions on Power Delivery (in press)

Co-simulation opens new opportunities to combine mature ElectroMagnetic Transients (EMT) and Phasor-Mode (PM) solvers, and take advantage of their respective high accuracy and execution speed. In this ... [more ▼]

Co-simulation opens new opportunities to combine mature ElectroMagnetic Transients (EMT) and Phasor-Mode (PM) solvers, and take advantage of their respective high accuracy and execution speed. In this paper, a relaxation approach is presented, iterating between an EMT and a PM solver. This entails interpolating over time the phasors of the PM simulation, extracting phasors from the time evolutions of the EMT simulation, and representing each sub-system by a proper multiport equivalent when simulating the other sub-system. Various equivalents are reviewed and compared in terms of convergence of the PM-EMT iterations. The paper also considers the update with frequency of the Thévenin impedances involved in the EMT simulation, the possibility to compute the EMT solution only once per time step, and the acceleration of convergence through a prediction over time of the boundary variables. Results are presented on a 74-bus, 23-machine test system, split into one EMT and one PM sub-system with several interface buses. [less ▲]

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See detailSemantic Integration by Pattern Priming: Experiment and Cortical Network Model
Lavigne, Frédéric; Longrée, Dominique ULg; Mellet, Sylvie

in Cognitive Neurodynamics (in press)

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See detailL'adolescent contemporain, la dette de vie et la question du don: apport de l'approche contextuelle
Haxhe, Stéphanie ULg; de Saint Georges, Marie-Christine; Michard, Pierre et al

in Adolescence (in press)

L’adolescent récuse la dette de vie et réclame autonomie et considération. Néanmoins, la société actuelle offre à l’adolescent des parents fragilisés. La réalité de l’adolescent contemporain apparaît ... [more ▼]

L’adolescent récuse la dette de vie et réclame autonomie et considération. Néanmoins, la société actuelle offre à l’adolescent des parents fragilisés. La réalité de l’adolescent contemporain apparaît alors comme une quête en tension entre une nécessaire appropriation de lui-même et des dons discrets à ses parents. Si ces dons ne sont pas reçus et échouent à introduire parents et adolescent à une nouvelle position relationnelle, le risque d’un épuisement de l’adolescent est à prendre en considération. [less ▲]

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See detailThe Sense of Taste in Eighteenth-Century France. Flavours of Silence and Words of Perception
Von Hoffmann, Viktoria ULg

in De achttiende eeuw : Documentatieblad van de Werkgroep Achttiende Eeuw (in press)

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See detailIs the sword moss (Bryoxiphium) a preglacial Tertiary relict?
Patino, J.; Goffinet, B.; Sim-Sim, M.A. et al

in Molecular Phylogenetics & Evolution (in press)

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See detailPlanetary Sapce Weather: Scientific Aspects and Future Perspectives
Plainaki; Lilensten; Radioti, Aikaterini ULg et al

in Space Science Reviews (in press)

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See detailBeyond survival and uncertainty. The livelihood practices of former Gécamines workers (D.R.Congo)
Rubbers, Benjamin ULg

in Review of African Political Economy (in press)

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See detailImaginer-lire le Capital
Pieron, Julien ULg

in Cahiers d'Etudes Germaniques (in press)

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See detailA qPCR aptasensor for sensitive detection of aflatoxin M1
Guo, Xiaodong; Wen, Fang; Zheng, Nan et al

in Analytical and Bioanalytical Chemistry (in press)

Aflatoxin M1 (AFM1), one of the most toxic mycotoxins, imposes serious health hazards. AFM1 had previously been classified as a group 2B carcinogen1 and has been classified as a group 1 carcinogen by the ... [more ▼]

Aflatoxin M1 (AFM1), one of the most toxic mycotoxins, imposes serious health hazards. AFM1 had previously been classified as a group 2B carcinogen1 and has been classified as a group 1 carcinogen by the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO).2 Determination of AFM1 thus plays an important role for quality control of food safety. In this work, a sensitive and reliable aptasensor was developed for the detection of AFM1. The immobilization of aptamer through a strong interaction with biotin–streptavidin was used as a molecular recognition element, and its complementary ssDNA was employed as the template for a real-time quantitative polymerase chain reaction (RT-qPCR) amplification. Under optimized assay conditions, a linear relationship (ranging from 1.0×10-4 to 1.0 µg L-1) was achieved with a limit of detection (LOD) down to 0.03 ng L-1. In addition, the aptasensor developed here exhibits high selectivity for AFM1 over other mycotoxins and small effects from cross-reaction with structural analogs. The method proposed here has been successfully applied to quantitative determination of AFM1 in infant rice cereal and infant milk powder samples. Results demonstrated that the current approach is potentially useful for food safety analysis, and it could be extended to a large number of targets. [less ▲]

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See detailLa collaboration entre architectes et plasticiens à Liège dans les années 1930.
Charlier, Sébastien ULg

in In Situ, revue des patrimoines (in press), 26

En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales ... [more ▼]

En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales, le mensuel revendique une vision transversale de l’architecture où la réflexion plastique occupe une place centrale. Dès le départ, elle s’associe à Anthologie, revue imprégnée des théories futuristes et qui diffuse les artistes de l’avant-garde locale. D’abord par le biais de l’édition et des expositions, plasticiens et architectes travaillent ensuite ensemble dans le cadre de projets ambitieux financés par les pouvoirs publics. Cette contribution revient aux racines de cette collaboration en définissant les liens théoriques ou personnels unissant les deux revues. En se concentrant sur les infrastructures publiques, elle comment les artistes et les architectes ont répondu ensemble aux exigences concrètes de la commande en les replaçant dans le contexte social, politique et économique d’une ville belge de seconde importance à la veille de la Seconde Guerre mondiale. [less ▲]

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See detailIncreased diversification rates correlate with bisexuality in liverworts
Laenen, B.; Machac, A.; Gradstein, S.R. et al

in New Phytologist (in press)

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See detailGeographic range in liverworts: does sex really matter?
Laenen, B.; Machac, A.; Gradstein, S.R. et al

in Journal of Biogeography (in press)

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See detailIngéniérie entre recherche et formation
Job, Pierre; Schneider-Gilot, Marguerite ULg

in Education et Didactique (in press)

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See detailEnergy conservation properties of Ritter solution for idealized dam break flow
Dewals, Benjamin ULg; Bruwier, Martin ULg; Erpicum, Sébastien ULg et al

in Journal of Hydraulic Research (in press)

We examine different aspects of energy conservation in the case of the analytical solution of Ritter for idealized dam break flow in a horizontal frictionless and dry channel. We detail the application of ... [more ▼]

We examine different aspects of energy conservation in the case of the analytical solution of Ritter for idealized dam break flow in a horizontal frictionless and dry channel. We detail the application of the unsteady Bernoulli equation in this case and highlight that the inertial effects cancel out when averaged over the whole flow region. We also show that the potential and kinetic contributions to the total mechanical energy in the flow region have a distinct and constant relative importance: potential energy accounts for 60 %, and kinetic energy for 40 % of the total mechanical energy. These properties of Ritter solution are rarely emphasized while they may be of practical relevance, particularly for the verification of numerical schemes with respect to their ability to ensure energy conservation. [less ▲]

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See detailLarge deviation spectra based on wavelet leaders
Bastin, Françoise ULg; Esser, Céline ULg; Jaffard, Stéphane ULg

in Revista Matemática Iberoamericana (in press)

We introduce a new multifractal formalism, based on distributions of wavelet leaders, which allows to detect non-concave and decreasing multifractal spectra, and we investigate the properties of the ... [more ▼]

We introduce a new multifractal formalism, based on distributions of wavelet leaders, which allows to detect non-concave and decreasing multifractal spectra, and we investigate the properties of the associated function spaces. [less ▲]

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See detailPlant evolution and terrestrialization during Palaeozoic times - the phylogenetic context
Gerrienne, Philippe ULg; Servais, Thomas; Vecoli, Marco

in Review of Palaeobotany and Palynology (in press)

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See detailPerformance characteristics of the VIDAS 25-OH Vitamin D total assay - comparison with four immunoassays and two liquid chromatography-tandem mass spectrometry methods in a multicentric study
Moreau, E; Bächer, S; Mery, S et al

in Clinical Chemistry & Laboratory Medicine (in press)

Background: The study was conducted to evaluate the analytical and clinical performance of the VIDAS® 25-OH Vitamin D Total assay. The clinical performance of the assay was compared with four other ... [more ▼]

Background: The study was conducted to evaluate the analytical and clinical performance of the VIDAS® 25-OH Vitamin D Total assay. The clinical performance of the assay was compared with four other immunoassays against the results of two different liquid chromatography/ mass spectrometry methods (LC-MS/MS) standardized to NIST reference materials. Methods: VIDAS® 25-OH Vitamin D Total assay precision, linearity, detection limits and sample matrix comparison were assessed following CLSI guidelines. For method comparison, a total of 150 serum samples ranging from 7 to 92 ng/mL were analyzed by all the methods. Correlation was studied using Passing-Bablok regression and Bland- Altman analysis. The concordance correlation coefficient (CCC) was calculated to evaluate agreement between immunoassays and the reference LC-MS/MS method. In addition, samples containing endogenous 25(OH)D2 were used to assess each immunoassay’s ability to detect this analyte. Pregnancy and hemodialysis samples were used to the study the effect of vitamin D binding protein (DBP) concentration over VIDAS® assay performance. Results: The VIDAS® 25-OH Vitamin D Total assay showed excellent correlation to the LC-MS/MS results (y = 1.01x+0.22 ng/mL, r = 0.93), as obtained from two different sites and distinct LC-MS/MS methods. The limit of quantification was determined at 8.1 ng/mL. Cross-reactivity for 25(OH)D2 was over 80%. At concentrations of 10.5, 26 and 65.1 ng/mL, within-run CVs were 7.9%, 3.6% and 1.7%, while total CVs (between runs, calibrations, lots and instruments) were 16.0%, 4.5% and 2.8%. The VIDAS® performance was not influenced by altered DBP levels, though under-recovery of 25(OH)D as compared to LC-MS/ MS was observed for hemodialysis samples. Conclusions: The VIDAS® 25-OH Vitamin D Total assay is therefore considered suitable for assessment of vitamin D status in clinical routine. Keywords: assay performance; liquid chromatography/ [less ▲]

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See detailHigh Resolution postontrast time of flight MR angiography of intracranial perforators at 7.0 Tesla
Harteveld, A; de Cocker, L; Dieleman, N et al

in American Journal of Neuroradiology (in press)

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See detailSiting Controversies Analysis: Framework and Method for Questioning the Procedure
Rossignol, Nicolas ULg; Parotte, Céline ULg; Joris, Geoffrey ULg et al

in Journal of Risk Research (in press)

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the ... [more ▼]

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the authorities, following a dynamics often quoted as ‘Not In My Back Yard’. Yet contested for its lack of analytical value, NIMBY is still used strategically by actors to qualify citizens as irrational and egoistic. Beyond this labelling, many factors are investigated to understand the dynamics behind siting controversies. In this paper, we focus on the impact of the legal procedure structuring the implantation of windfarms in the Walloon Region (Belgium), and its translations within different decision making processes in specific case studies. To that regard, we consider the legal procedure as a ‘public policy instrument’. It is neither neutral nor natural, and carry values and interests. It organizes inter-personal relations between actors, and is potentially catalyzer of frustrations. In addition, this legal procedure is the object of translations within different contexts, including different actors participating to specific decision making processes. The empirical approach of this paper is based on case studies data and on the use of an innovative methodology called ‘Open Process Workshop’. This methodology consists in a structured workshop with key stakeholders, during which the legal procedure is questioned. Overall, we demonstrate that the focus on the legal procedure - and its translations within different decision making processes - allows systemic analysis providing deep understandings of controversies and reaffirming the interlinks between ‘the social’ and ‘the technical’ in such controversies. In addition, we argue that the methodology used fosters the production of innovative knowledge, mutual understanding and collective learning between the participants. [less ▲]

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See detail1 Conjoint influence of mind-wandering and sleepiness on task performance
Stawarczyk, David ULg; D'Argembeau, Arnaud ULg

in Journal of Experimental Psychology. Human Perception & Performance (in press)

Recent research suggests that sleepiness and mind-wandering—the experience of thoughts that are both stimulus-independent and task-unrelated—frequently co-occur and are both associated with poorer ... [more ▼]

Recent research suggests that sleepiness and mind-wandering—the experience of thoughts that are both stimulus-independent and task-unrelated—frequently co-occur and are both associated with poorer cognitive functioning. Whether these two phenomena have distinguishable effects on task performance remains unknown, however. To investigate this question, we employed the online experience sampling of mind-wandering episodes and subjective sleepiness during a laboratory task (the Sustained Attention to Response Task; SART), and also assessed mind-wandering frequency and sleep-related disturbances in daily life using self-report questionnaires. The results revealed that the tendency to experience mind-wandering episodes during the SART and daily life was associated with higher levels of daytime sleepiness and sleep-related disturbances. Importantly, however, mind-wandering and sleepiness were independent predictors of SART performance at both the within- and between-individuals levels. These findings demonstrate that, although mind-wandering and sleepiness frequently co-occur, these two phenomena have distinguishable and additive effects on task performance. [less ▲]

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See detailPrudence et ruse comme capacités d’action managériale et politique. Le cas des équipes de direction pénitentiaire belges
Dubois, Christophe ULg

in Sociologie (in press), 7(4),

This paper aims at analysing the work of prison management teams. Working in organizations that are mainly "auto-regulated" by prison guards, governors’ teams have to cope, for the last fifteen years ... [more ▼]

This paper aims at analysing the work of prison management teams. Working in organizations that are mainly "auto-regulated" by prison guards, governors’ teams have to cope, for the last fifteen years, with a heightened control exercised by the central administration. This “regulation of control” (Reynaud, 1988) is inter alia justified by the endemic phenomenon of overcrowding and the increasing interdependency between prisons and their environment. Despite the constraints implied by these shifts, prison governors preserve some autonomy through two types of deliberative practice allowing them to influence - marginally and ethically – prison organizations and policies. The first one, called practical wisdom or prudence (Champy, 2012), lies in the subtle bypass of the rules in uncertain situations; the second one, called cunning, or ruse (Lécu, 2013), consists in denouncing the hypocrisy of some political discourses with the help of some external partners. [less ▲]

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See detailInfectivity of a recombinant murine norovirus (RecMNV) in Balb/cByJ mice
Mathijs, Elisabeth; de Oliveira-Filho, Edmilson; Dal Pozzo, Fabiana ULg et al

in Veterinary Microbiology (in press)

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See detailPhysiological and bio-functional properties of gum arabic: a notable interest for certain human diseases
Eloundou Mballa, Pierre; Goffin, Dorothée ULg; Destain, Jacqueline ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

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See detailSpecific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice
Scoumanne, Ariane; Molina Ortiz, Patricia ULg; Monteyne, Daniel et al

in Advances in Biological Regulation (in press)

Inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) is the last identified member of the inositol 1,4,5-trisphosphate 3-kinases family which phosphorylates inositol 1,4,5-trisphosphate into inositol 1,3,4,5 ... [more ▼]

Inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) is the last identified member of the inositol 1,4,5-trisphosphate 3-kinases family which phosphorylates inositol 1,4,5-trisphosphate into inositol 1,3,4,5-tetrakisphosphate. Although expression and function of the two other family members ITPKA and ITPKB are rather well characterized, similar information is lacking for ITPKC. Here, we first defined the expression of Itpkc mRNA and protein in mouse tissues and cells using in situ hybridization and new antibodies. Surprisingly, we found that cells positive for ITPKC in the studied tissues express either a multicilium (tracheal and bronchial epithelia, brain ependymal cells), microvilli forming a brush border (small and large intestine, and kidney proximal tubule cells) or a flagellum (spermatozoa), suggesting a role for ITPKC either in the development or the function of these specialized cellular structures. Given this surprising expression, we then analyzed ITPKC function in multiciliated tracheal epithelial cells and sperm cells using our Itpkc knock-out mouse model. Unfortunately, no significant difference was observed between control and mutant mice for any of the parameters tested, leaving the exact in vivo function of this third Ins(1,4,5)P3 3-kinase still open. [less ▲]

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See detailReview: Implementing biostimulants and biocontrol strategies in the agroecological management of cultivated ecosystems
Le Mire, Géraldine ULg; Nguyen, Minh ULg; Fassotte, Bérénice ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

This review describes the current methods for exploiting and applying plant growth-promoting rhizbacteria (PGPR), elicitors and semiochemical products in contemporary agricultural systems. The future of ... [more ▼]

This review describes the current methods for exploiting and applying plant growth-promoting rhizbacteria (PGPR), elicitors and semiochemical products in contemporary agricultural systems. The future of these biostimulant and biocontrol tools for the sustainable management of agricultural practices is also discussed. Special attention is given to the formulation of these products and the network of interactions taking place in cultivated ecosystems [less ▲]

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See detailEpistémologie de la théorie du complot
Jamin, Jérôme ULg

in Cahiers de l'Éducation Permanente (Les) (in press)

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See detailOccurrence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary, Argentina, and their mid-distance movements along the Northeast Patagonian coast
Failla, Mauricio; Seijas, Veronica; Vermeulen, Els ULg

in Latin American Journal of Aquatic Mammals (in press)

A systematic study on the presence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary (RNE), Patagonia Argentina, was carried out between the months March – July from 2008 to 2011. Data ... [more ▼]

A systematic study on the presence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary (RNE), Patagonia Argentina, was carried out between the months March – July from 2008 to 2011. Data on the dolphin’s activity patterns were gathered via an Ad Libitum focal group sampling mode accompanying dorsal fin images taken for identification and re-identification of individuals. A total effort of 188 h resulted in 58 h of positive observation of 124 dolphin groups (sightings per unit effort (SPUE) = 0.66 groups/h). Data analysis showed two main activity states for the observed groups, travelling (65%) and foraging (26%). The remaining 9% of the groups were involved in other activity states. The photo-identification effort, which started opportunistically in 2006, resulted in a catalogue of 21 individual dolphins, with a total mean re-identification rate of 9 days (max = 24 days). When comparing these pictures to the existing catalogue of Bahía San Antonio (approximately 200 km west from the study area) dorsal fins of 20 individuals could be positively matched and most (n = 17) could be subsequently re-identified in both areas, indicating their long distance movements along the North Patagonian coast during the austral autumn months. This season coincides with the lowest amount of feeding activity observed in Bahía San Antonio. This study suggests that bottlenose dolphins enter RNE, mainly during autumn, to forage. It appears that the search for food resources may be the trigger for their movement patterns along the North Patagonian coast during this season, at least for certain individuals. More research is needed to accurately confirm this hypothesis. [less ▲]

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See detailLoop
Levaux, Christophe ULg

in Rock Music Studies (in press)

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See detailGlioblastoma-derived extracellular vesicles induce tumor-supportive phenotypes in monocytic cells
de Vrij, Jeroen; Maas, Sybren; Kwappenberg, Kitty et al

in International Journal of Cancer = Journal International du Cancer (in press)

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See detailAqueous sol-gel synthesis and film deposition methods for the large-scale manufacture of coated steel with self-cleaning properties
Mahy, Julien ULg; Léonard, Géraldine ULg; Pirard, Sophie ULg et al

in Journal of Sol-Gel Science and Technology (in press)

A process has been developed to enable the large scale production of pure TiO2 films deposited on 316L stainless steel in order to get an easy-to-clean surface. This large scale process requires an easy ... [more ▼]

A process has been developed to enable the large scale production of pure TiO2 films deposited on 316L stainless steel in order to get an easy-to-clean surface. This large scale process requires an easy aqueous sol-gel procedure for the synthesis of the TiO2 sol. This synthesis has been simplified to facilitate the extrapolation towards an industrial scale. Results of TEM, photocatalytic properties, film hydrophilicity, and texture obtained with the simplified aqueous sol-gel synthesis (IsoP-TiO2 synthesis) show similar properties to those obtained with the standard aqueous sol-gel synthesis of TiO2 (HAc-TiO2 synthesis) developed previously. Only X-Ray Diffraction patterns showed differences, with the presence of anatase-brookite phases in IsoP-TiO2 synthesis while anatase phase only was observed in HAc-TiO2 synthesis. Both the aqueous sol-gel synthesis of pure TiO2 and the film deposition on steel by roll-coating have been successfully extrapolated to a larger scale. The photocatalytic activity and the hydrophilicity of the film were found to be unchanged when compared to films produced at a laboratory scale, thus validating the production of an efficient easy-to-clean material. Although some problems are still to be solved, this study is a hopeful first step in the development of a large scale process for self-cleaning steel production. [less ▲]

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See detailWhom do architects design for in design competitions? A case study
Verhulst, Lore; Elsen, Catherine ULg; Heylighen, Ann

in Journal of Design Research (in press)

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See detailEffects of 10Hz and 20Hz transcranial alternating current stimulation on automatic motor control
Cappon, Davide; D'Ostilio, Kevin ULg; Garraux, Gaëtan ULg et al

in Brain Stimulation (in press)

Background: Automatic motor inhibition is an important and adaptive process through which an activated motor plan is suppressed if the movement is not intended to be executed. Neuronal networks are ... [more ▼]

Background: Automatic motor inhibition is an important and adaptive process through which an activated motor plan is suppressed if the movement is not intended to be executed. Neuronal networks are characterized by oscillatory activity. In the brain, a large variety of rhythms have been described that differ in their frequency, origin and reactivity to changes in task demands. Recent studies have demonstrated that active cortical networks are susceptible to weak sinusoidal perturbations of exogenous electric fields. Objective/Hypothesis: The aim of this study was to investigate the frequency-specific effect of transcranial alternate current stimulation (tACS) over the automatic control of movement in healthy volunteers. We hypothesized that applying two different tACS frequencies during a visuo-motor task would result in different behavioural effects and in diverse modulation of cortical excitability. Methods: In this study we used tACS to interact non-invasively with the ongoing task-related oscillatory activity. Stimulation was delivered at alpha (10 Hz) and beta (20 Hz) frequency over the supplementary motor area and the primary motor cortex (SMA-M1) connections, which are part of the BG-cortical motor loop, during the execution of the subliminal masked prime task. We measured the effects on task performance and on motor cortex corticospinal excitability by means of motor evoked potentials (MEPs) evoked by transcranial magnetic stimulation (TMS). Results: Results indicate a specific effect of 10 and 20-Hz tACS on functional inhibition in the SMA-M1 circuit. Behaviorally there is an interference in task-related automatic inhibition: 10 Hz tACS reduced the automatic inhibition. In contrast 20 Hz tACS increased the automatic inhibition. At a neurophysiological level there is a modulation in excitability of M1: 20 Hz tACS reduced MEP amplitudes, whereas there was no change after 10 Hz tACS. Conclusion(s): The current study provides novel evidence that automatic mechanisms of motor behaviour can be modulated by imposing synchronized electrical oscillatory activity upon motor cortical regions. Our study has important implications for cognitive neuroscience studies suggesting that the use tACS might offer the possibility to demonstrate a causal link between endogenous brain oscillations, specific exogenous alternate current frequencies and specific cognitive processes. [less ▲]

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See detailLes associations des enfants et jeunes travailleurs du Burkina Faso comme espace d’expression de la capacité d’action des enfants ?
Wouango, Joséphine ULg

in Enfances Familles Générations (in press)

Les Associations des Enfants et Jeunes Travailleurs du Burkina Faso (AEJT/BF) sont une représentation nationale du Mouvement Africain des Enfants et Jeunes Travailleurs (MAEJT), créé à la fin des années ... [more ▼]

Les Associations des Enfants et Jeunes Travailleurs du Burkina Faso (AEJT/BF) sont une représentation nationale du Mouvement Africain des Enfants et Jeunes Travailleurs (MAEJT), créé à la fin des années 1980. Le mouvement est fondé sur deux grands principes : les douze droits prioritaires des enfants et jeunes travailleurs et le principe du « protagonisme » (l’enfant travailleur comme acteur capable) . Ce chapitre présente et analyse le fonctionnement de ce mouvement au Burkina Faso, les changements qu’il a contribué à apporter à la question sociale du travail des enfants et les résultats de la mise en application des principes annoncés. S’appuyant sur une enquête ethnographique menée en son sein, le texte offre des données inédites sur les réalités d’un acteur collectif qui, en utilisant à son avantage la rhétorique de la « participation » des enfants (art.12, Convention des droits de l’enfant), a réussi à s’insérer dans l’arène nationale de la protection de l’enfance. Toutefois, la question de la place et du rôle des enfants ainsi que celle du “vieillissement” des membres sont quelques-uns des défis auxquels la section burkinabè du mouvement doit faire face. [less ▲]

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See detailThe right dorsal premotor mosaic: organization, functions, and connectivity
Genon, Sarah ULg; Li, Hai; Fan, Lingzhong et al

in Cerebral Cortex (in press)

The right dorsal premotor cortex (PMd) of humans has been reported to be involved in a broad range of motor and cognitive functions. We explored the basis of this behavioral heterogeneity by performing a ... [more ▼]

The right dorsal premotor cortex (PMd) of humans has been reported to be involved in a broad range of motor and cognitive functions. We explored the basis of this behavioral heterogeneity by performing a connectivity-based parcellation using meta-analytic approach applied to PMd coactivations. We compared our CBP results to parcellations obtained through resting-state functional connectivity and probabilistic diffusion tractography,. Functional connectivity profiles and behavioral decoding of the resulting PMd subregions allowed characterizing their respective behavior profile. These procedures divided the right PMd into five distinct subregions that formed a cognitive-motor gradient along a rostro-caudal axis. In particular, we found (i) a rostral subregion functionally connected with prefrontal cortex, which likely supports high-level cognitive processes, such as working memory (ii) a central subregion showing a mixed behavioral profile and functional connectivity to parietal regions of the dorsal attention network, and (iii) a caudal subregion closely integrated with the motor system. Additionally, we found (iv) a dorsal subregion, preferentially related to hand movements and connected to both cognitive and motor regions, and (v) a ventral subregion, whose functional profile fits the concept of an eye-movement related field. In conclusion, right PMd may be considered as a functional mosaic formed by five subregions. [less ▲]

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See detailIntercomparison of in-situ NDIR and column FTIR measurements of CO2 at Jungfraujoch
Schibig, M. F.; Mahieu, Emmanuel ULg; Henne, S. et al

in Atmospheric Chemistry and Physics (in press)

We compare two CO2 time series measured at the High Alpine Research Station Jungfraujoch (3580 m a.s.l., Switzerland) in the period from 2005 to 2013 with an in-situ surface measurement system using a ... [more ▼]

We compare two CO2 time series measured at the High Alpine Research Station Jungfraujoch (3580 m a.s.l., Switzerland) in the period from 2005 to 2013 with an in-situ surface measurement system using a nondispersive infrared analyzer (NDIR) and a ground-based remote sensing system using solar absorption Fourier Transform Infrared spectrometry (FTIR). Although the two data sets show an absolute shift of about 13 ppm, the slopes of the annual CO2 increase are in good agreement within their uncertainties. They are 2.04 ± 0.07 19 ppm yr-1 and 1.97 ± 0.05 ppm yr-1 for the FTIR and the NDIR system, respectively. The seasonality of the FTIR and the NDIR system is 4.46 ± 1.11 ppm and 10.10 ± 0.73 ppm, respectively. The difference is caused by a dampening of the CO2 signal with increasing altitude due to mixing processes. While the minima of both data series occur in the middle of August, the maxima of the two datasets differ by about ten weeks, the maximum of the FTIR measurements is in middle of January, whereas the maximum of the NDIR measurements is found at the end of March. Sensitivity analyses revealed that the air masses measured by the NDIR system at the surface of Jungfraujoch are mainly influenced by central Europe, whereas the air masses measured by the FTIR system in the column above Jungfraujoch are influenced by regions as far west as the Caribbean and the United States. [less ▲]

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See detailBiochemical characterization of the oil of durum wheat germ (Tunisian variety)
Kammoun, Maroua; Rassâa, Neila; Mejri-Gaïda, Myriam et al

in Journal of New Sciences (in press)

The wheat germ oil may constitute an alternative to the misuse of this cereal grain resource. The Tunisian exploitation is limited, at present, in the human and animal feed in the grain form, straw or ... [more ▼]

The wheat germ oil may constitute an alternative to the misuse of this cereal grain resource. The Tunisian exploitation is limited, at present, in the human and animal feed in the grain form, straw or some transformed products. For the purpose of characterization, the wheat germ oil has been extracted by Soxhlet apparatus from a Tunisian variety of durum wheat (Maali) based on the hexane as a solvent. An analysis by gas chromatography (GC) was then performed to identify and quantify the fatty acids of the oil. Then, the oil has submitted to a second chromatography analysis in liquid phase (HPLC) to quantify the tocopherols. The most important fatty acids constituting have been the two polyunsaturated acids linoleic acid C18:2 (OMEGA 6) and the gamma acid- linoleic C18:3 : 58.24 % and 4.19 % respectively; and the acid monounsaturated oleic acid C18:1 ( 24.49 %) but also some saturated acid: palmitic acid C16:0 with ( 19.50 % ), and the stearic acid C18:0 (1.29%). For this variety of Tunisian durum wheat, the wheat germ oil contains, in addition, 80.27 mg / 100g of α- tocopherols (vitamin E). The wheat germ oil extracted from the Tunisian variety 'Maali' has proved rich in vitamin E and omega-6 ; a better valorisation on the nutritional or pharmaceutical plan is to this title recommended. [less ▲]

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See detailMetabolic variability in bioprocessing : implications of microbial phenotypic heterogeneity
Delvigne, Frank ULg; Zune, Quentin ULg; Lara, Alvaro et al

in Trends in Biotechnology (in press)

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See detailUse of Tyrosine Kinase Inhibitors to Prevent Relapse After Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Position Statement of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Giebel, S.; Czyz, A.; Ottmann, O. et al

in Cancer (in press)

Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a standard of care for patients with Philadelphia chromosome (Ph)–positive acute lymphoblastic leukemia (ALL). The introduction of tyrosine ... [more ▼]

Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a standard of care for patients with Philadelphia chromosome (Ph)–positive acute lymphoblastic leukemia (ALL). The introduction of tyrosine kinase inhibitors (TKIs) to first-line therapy has improved overall outcomes; however, a significant proportion of patients still relapse after alloHSCT. Posttransplant TKI maintenance was demonstrated to reduce the risk of relapse in a large retrospective study and, therefore, should be considered a valuable option. This consensus paper, written on behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation, presents an overview of clinical studies on the use of TKIs after alloHSCT and proposes practical recommendations regarding the choice of TKI, treatment timing, and dosage. It is hoped that these recommendations will become the state of art in this field and, more importantly, lead to a reduction of Ph-positive ALL relapse after alloHSCT. [less ▲]

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See detailAgeism in Belgium and Burundi: A comparative analysis
Marquet, Manon ULg; Missotten, Pierre ULg; Schroyen, Sarah ULg et al

in Clinical Interventions in Aging (in press)

Background: Recent cross-cultural comparisons between Asian and Western cultures have shown that ageism arises more from the lack of availability of social and economic resources for older adults than ... [more ▼]

Background: Recent cross-cultural comparisons between Asian and Western cultures have shown that ageism arises more from the lack of availability of social and economic resources for older adults than from the culture itself. We tested this assumption by conducting a survey among people living in a least-developed country compared with a developed country. Methods: Twenty-seven Belgians living in Belgium, 29 Burundians living in Belgium and 32 Burundians living in Burundi were included in this study. Their attitudes toward older adults were assessed using several self-reported measures. Results: Statistical analyses confirmed that older people are more negatively perceived by Burundians living in Burundi than by Burundians and Belgians living in Belgium, whose attitudes did not differ from each other. Conclusion: Consistent with our hypothesis, our results suggest that the level of development of a country and more particularly the lack of government spending on older people (pension and healthcare systems) may contribute to their younger counterparts perceiving them more negatively. [less ▲]

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See detailThe color ratio-intensity relation in the Jovian aurora: Hubble observations of auroral components
Gérard, Jean-Claude ULg; Bonfond, Bertrand ULg; Grodent, Denis ULg et al

in Planetary and Space Science (in press), (1),

Spectral observations made with the long slit of the Space Telescope Imaging Spectrograph (STIS) on board Hubble have been used to construct spectral maps of the FUV Jovian aurora. They reveal that the ... [more ▼]

Spectral observations made with the long slit of the Space Telescope Imaging Spectrograph (STIS) on board Hubble have been used to construct spectral maps of the FUV Jovian aurora. They reveal that the amount of absorption by overlying methane shows significant spatial variations. In this report, we examine the relationship between the auroral brightness of the unabsorbed H2 emission that is proportional to the precipitated electron energy flux, and the ultraviolet color ratio, a proxy of the mean electron energy. We find that it varies significantly between the different components of the aurora and in the polar region. Although no global dependence can be found, we show that the two quantities are better organized in some auroral components such as regions of the main aurororal emission. By contrast, the dependence of the electron characteristic energy in high-latitude and diffuse aurora regions on the auroral energy input is generally more scattered. We conclude that the various auroral components are associated with different electron acceleration processes, some of which are not governed by a simple relation linking the value of a field-aligned acceleration potential with the parallel currents flowing from the ionosphere. [less ▲]

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See detailRevealed preference tests of collectively rational consumption behavior: formulations and algorithms
Talla Nobibon, Fabrice; Cherchye, Laurens; Crama, Yves ULg et al

in Operations Research (in press)

This paper focuses on revealed preference tests of the collective model of household consumption. We start by showing that the decision problems corresponding to testing collective rationality are {\sc np ... [more ▼]

This paper focuses on revealed preference tests of the collective model of household consumption. We start by showing that the decision problems corresponding to testing collective rationality are {\sc np}-complete. This makes the application of these tests problematic for (increasingly available) large(r) scale data sets. We then present two approaches to overcome this negative result. First, we introduce exact algorithms based on mixed-integer programming ({\sc mip}) formulations of the collective rationality tests, which can be usefully applied to medium sized data sets. Next, we propose simulated annealing heuristics, which allow for efficient testing of the collective model in the case of large data sets. We illustrate our methods by a number of computational experiments based on Dutch labor supply data. [less ▲]

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See detailInfluence of the balls kinematics of axially loaded ball bearings on Coulombic frictional dissipations
Bozet, Jean-Luc ULg; Servais, Christophe ULg

in Journal of Tribology (2017), 139(1),

Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact ... [more ▼]

Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact balls kinematics has still to be addressed in depth. This paper proposes a new way to calculate the balls kinematics by using a simplified quasi-static approach for dry lubricated and axially loaded ball bearings. This method does not use the classical restrictive race control assumptions. More specifically, the role played by the balls kinematics is emphasized by means of the power dissipated within contacts between balls and races. The need for a correct evaluation of the balls behavior is illustrated by using an example, viz. a ball bearing of cryogenic engine turbopump. Indeed, the dissipated power is one of the main concerns in this particular case. [less ▲]

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See detailIconic virtues of diagrams. Peirce on ampliative reasoning
Leclercq, Bruno ULg

in Signata. Annales des Sémiotiques = Annals of Semiotics (2017)

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See detailLe commun à l'épreuve du conflit : médiation esthétique et expérience de la communauté
Servais, Christine ULg

in Recherches en Communication (2017)

Cet article propose une conception de la médiation culturelle où la notion de médiation est lestée d’un rapport complexe au tiers, rapport susceptible de prendre en compte le conflit que peut constituer ... [more ▼]

Cet article propose une conception de la médiation culturelle où la notion de médiation est lestée d’un rapport complexe au tiers, rapport susceptible de prendre en compte le conflit que peut constituer la prise de position du destinataire auquel s’adressent les dispositifs de médiation. Cette approche de la médiation conserve la distinction entre passage et forçage, ce qui la situe dans un cadre politique. [less ▲]

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See detailAdresse, opinion et responsabilité : un modèle de la subjectivation en public
Servais, Christine ULg

in Questions de Communication (2017)

Cet article interroge la relation entre « publics » et « collectifs » et en propose un modèle de description à caractère phénoménologique. Après un examen des implications politiques des modèles auxquels ... [more ▼]

Cet article interroge la relation entre « publics » et « collectifs » et en propose un modèle de description à caractère phénoménologique. Après un examen des implications politiques des modèles auxquels sont susceptibles de se référer les théories de la réception médiatique, on tente d’élaborer, à partir du travail de Stiegler, de Rancière et de Derrida, une approche de la réception qui permet de décrire à la fois l’émancipation et la domination, cette alternative étant l’un des points de butée des théories de la réception. Le critère déterminant est ici l’adresse, considérée comme la traduction en termes phénoménologiques de l’énonciation. La réception est alors envisagée comme une réponse à une adresse. Cette conception de l’énonciation rend compte de la dimension politique d’une réception médiatique où l’identité sociale est désormais indexée sur notre identité de destinataires de dispositifs médiatique, c’est-à-dire de publics [less ▲]

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See detailLoadbearing capacity criteria in fire resistance testing
Dumont, Fabien ULg; Wellens, Eric ULg; Gernay, Thomas ULg et al

in Materials and Structures (2016), 49(11), 4565-4581

The European system for fire testing and classification of loadbearing building elements lacks consistency because the two standards that have to be applied prescribe different criteria for assessing the ... [more ▼]

The European system for fire testing and classification of loadbearing building elements lacks consistency because the two standards that have to be applied prescribe different criteria for assessing the loadbearing performance. This article analyzes the implications of the present conflict between the standard for testing and the standard for classification. The prescribed criteria for loadbearing performance are related to the exceedance of deflection and rate of deflection thresholds. A database of 46 fire resistance tests performed at the University of Liege is collected that contains the time at which these thresholds are reached in fire tests with different typologies of elements (walls, floors, columns and beams). Then, the loadbearing performance (and hence the fire resistance rating) can be derived according to the two standards. The evolutions of deflection and rate of deflection during the tests are also analyzed to gain a better understanding of the adequacy of the standards. The selection of one or the other standard affects the time at which “failure” is deemed to occur in fire tests. Statistically speaking, the difference in terms of failure time that results from using one or the other standard has a 25% probability to exceed 10%. In certain cases, this results in a difference in fire resistance rating; this was observed for 3 of the analyzed tests. The apparent contradiction in two codes in application has potential practical implications and therefore needs to be solved. The article suggests some guidelines for defining homogenized and consistent criteria. [less ▲]

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See detailSU(3) Clebsch-Gordan coefficients at large $N_c$
Stancu, Floarea ULg

in Nuclear Physics A (2016), 945

It is argued that several papers where SU(3) Clebsch-Gordan coefficients were calculated in order to describe properties of hadronic systems are, up to a phase convention, particular cases of analytic ... [more ▼]

It is argued that several papers where SU(3) Clebsch-Gordan coefficients were calculated in order to describe properties of hadronic systems are, up to a phase convention, particular cases of analytic formulae derived by Hecht in 1965 in the context of nuclear physics. This is valid for irreducible representations with multiplicity one in the corresponding Clebsch-Gordan series. For multiplicity two, Hecht has proposed an alternative which can provide correct $1/N_c$ sub-leading orders in large $N_c$ studies. [less ▲]

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See detailTowards a large scale aqueous sol-gel synthesis of doped TiO2: Study of various metallic dopings for the photocatalytic degradation of p-nitrophenol
Mahy, Julien ULg; Lambert, Stéphanie ULg; Léonard, Géraldine ULg et al

in Journal of Photochemistry and Photobiology A : Chemistry (2016), 329

In this paper, an easy aqueous sol-gel synthesis developed previously by Mahy et al. [J. Sol-Gel Sci. Technol. (2016)] is adapted to produce highly active TiO2 catalysts doped with Fe3+, Ag+, Cu2+, Zn2 ... [more ▼]

In this paper, an easy aqueous sol-gel synthesis developed previously by Mahy et al. [J. Sol-Gel Sci. Technol. (2016)] is adapted to produce highly active TiO2 catalysts doped with Fe3+, Ag+, Cu2+, Zn2+, Cr3+, Al3+, Mn2+, and Co2+ ions and Pt metallic nanoparticles. Samples are characterized by inductively coupled plasma–atomic emission spectroscopy (ICP-AES), X-ray diffraction (XRD), Mössbauer spectroscopy, transmission electron microscopy (TEM), nitrogen adsorption–desorption measurements and diffuse reflectance spectroscopy measurements. Results show that the samples are composed of anatase-brookite TiO2 nanoparticles with a spherical shape and mean diameter of around 5-8 nm and a surface area of between about 150 - 250 m2 g-1. In each doped sample, the dopant is present in the form added during the synthesis, given that the sample has not undergone any particular treatment. Photoactivity tests show improvement in catalyst activity for Fe3+, Ag+, Cu2+, Zn2+, and Al3+ ion and Pt metallic nanoparticle dopants, while a decrease of activity is obtained for Cr3+, Mn2+ and Co2+ ion dopants. For some dopants, the activity of TiO2 doped with metallic ions and synthesized from the aqueous sol-gel process is equal or superior to the activity of the commercial photocatalyst Degussa P25. Some mechanisms are proposed to explain these modifications of activity with doping. Furthermore, cost comparison at laboratory scale showed that Zn and Cu nitrate salt dopings are clearly less expensive for a halogen light (UV/visible) or low energy light enhanced catalyst and may be considered for industrial applications. Using this method, a large scale Zn-doped TiO2 photocatalyst is synthesized with properties homologous to the lab-scale product. Results show that the aqueous sol-gel synthesis developed previously can be easily adapted for doping in order to produce an up-scalable synthesis. [less ▲]

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See detailL’approche sémiotique de Charles Goodwin : langage visuel, énonciation et diagramme
Dondero, Maria Giulia ULg

in Tracés. Revue de Sciences Humaines (2016), 3(automne),

This text investigates the connexion between the work of Charles Goodwin and contemporary semiotics. I initially address the relations between verbal, visual, and gestural languages in semiotic terms by ... [more ▼]

This text investigates the connexion between the work of Charles Goodwin and contemporary semiotics. I initially address the relations between verbal, visual, and gestural languages in semiotic terms by exploring the Goodwin’s notational system (transcription of exchanges) from the point of view of its constituent units. Secondly, I consider the meeting points between Goodwin’s concept of the substrate and Fontanille’s enunciative praxis in order to examine the dynamic relationship between sedimentation and transformation. Finally, I analyse the concept of diagrammatic reasoning by elaborating on the example of the geologists’ “first inscriptions” studied by Goodwin. The form of diagrammatic reasoning examined here functions as a discovery device that exemplifies the dynamics of sedimentation and novelty, and it can thus be studied in the framework of Goodwin’s transcription practices. [less ▲]

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See detailDu stilus à la plume ... du chapeau. Quelques réflexions sur la notion de style
Houbart, Claudine ULg

in Bruxelles Patrimoines (2016), (18),

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See detailVoir en art, voir en sciences
Dondero, Maria Giulia ULg

in Nouvelle Revue d'Esthétique (2016), 17

This article is about visual devices that in history of art and in semiotics are generally called "metavisual" and that are used to study some phenomena of framing in artistic images (see the works of ... [more ▼]

This article is about visual devices that in history of art and in semiotics are generally called "metavisual" and that are used to study some phenomena of framing in artistic images (see the works of Victor Stoichita and of Jean-François Bordron). We are going to explore the possibility to use these devices to analyse contemporary scientific images, trying to identify some common actions that go beyond the differences in terms of objects and economy of values between arts and sciences. [less ▲]

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See detailAbility of Tuta absoluta (Lepidoptera: Gelechiidae) to develop on alternative host plant species
Bawin, Thomas ULg; Dujeu, David; De Backer, Lara ULg et al

in Canadian Entomologist (2016), 148(4), 434-442

The tomato leafminer, Tuta absoluta Meyrick (Lepidoptera: Gelechiidae), is a widespread devastating pest reported to develop on economically important solanaceous crops. The characterization of its host ... [more ▼]

The tomato leafminer, Tuta absoluta Meyrick (Lepidoptera: Gelechiidae), is a widespread devastating pest reported to develop on economically important solanaceous crops. The characterization of its host range could help to understand and prevent the dispersion behavior of the insect in the environment. In this study, the ability of T. absoluta to develop on 12 cultivated or non-cultivated plants including Solanaceae, Chenopodiaceae, Convolvulaceae, Fabaceae and Malvaceae species under laboratory conditions was assessed. For each plant species, we monitored the development times of immature stages, survival, sex ratios and adult fecundity rates. All the 6 tested non-solanaceous plants, including Chenopodium, Convolvulus and Malva species, were not able to sustain (i.e. allow growth and development) T. absoluta larvae. Among Solanaceae, Solanum species were the most suitable host plants for the pest, but others could be opportunistically colonized with fewer incidences. T. absoluta appears to be strongly related to solanaceous plants which would predominantly support self-sustaining field populations. Preventing crop infestation by removing potential host plants in the immediate field vicinity and culture rotations with non-solanaceous crops is of primary importance. [less ▲]

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See detailHydrocarbon biostimulation and bioaugmentation in organic carbon and clay-rich soils
Masy, Thibaut ULg; Demanèche, Sandrine; Tromme, Olivier et al

in Soil Biology & Biochemistry (2016), 99

Hydrocarbon-contaminated organic carbon-rich clayey soils are challenging for bioremediation stakeholders since the pollutant is heterogeneously distributed and poorly bioavailable due to its strong ... [more ▼]

Hydrocarbon-contaminated organic carbon-rich clayey soils are challenging for bioremediation stakeholders since the pollutant is heterogeneously distributed and poorly bioavailable due to its strong adsorption on clay and organic particles. In addition, biodegradation rates are restricted by limited diffusion of oxygen and nutrients to hydrocarbon-degrading aerobes. This study assessed the benefits of bioaugmentation with the strain Rhodococcus erythropolis T902.1 versus those from biostimulation and anaerobic natural attenuation in terms of hydrocarbon (HC) degradation efficiency and changes in the bacterial community structure in a diesel-polluted clay-rich soil. Three soil samples with a similar total organic content but with a different HC concentration (0.2, 1.0 and 6.5 g/kg) were compared in a microcosm experiment. Despite a limitation in oxygen transfer, R. erythropolis T902.1 enhanced a greater HC degradation compared to the biostimulation treatment. However, this advantage decreased with time as the proportion of Rhodococci declined from 25% initially to 1% of the global community after 80 days of treatment. Similarly, the alkB gene proportion in bioaugmented soils decreased to levels close to those of biostimulated soils. Consequently, further engineering was suggested to improve the resilience of the inoculum to ensure its long-term presence and activity in such polluted environments. [less ▲]

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See detailEffects of aging on task- and stimulus-related cerebral attention networks
Kurth, Sophie ULg; Majerus, Steve ULg; Bastin, Christine ULg et al

in Neurobiology of Aging (2016), 44

Interactions between a dorsal attention (DAN) and a ventral attention cerebral network (VAN) have been reported in young participants during attention or short term memory (STM) tasks. Since it remains an ... [more ▼]

Interactions between a dorsal attention (DAN) and a ventral attention cerebral network (VAN) have been reported in young participants during attention or short term memory (STM) tasks. Since it remains an under-investigated question, age effects on DAN and VAN activity and their functional balance were explored during performance of a STM task. Older and young groups showed similar behavioral patterns of results. At the cerebral level, DAN activation increased as a function of increasing STM load in both groups, suggesting preserved activity in DAN during healthy aging. Age-related over-recruitment in regions of the DAN in the higher task load raised the question of compensation attempt versus less efficient use of neural resources in older adults. Lesser decrease of VAN activation with increasing load and decreased stimulus-driven activation in the VAN, especially in the higher load, in older participants suggested age-related reduced response in the VAN. However, functional connectivity measures showed that VAN was still functionally connected to the DAN in older participants. [less ▲]

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See detailCollaborative Care regarding major depressed patients: A review of guidelines and current practices
Van den Broeck, Kris; Remmen, Roy; Vanmeerbeek, Marc ULg et al

in Journal of Affective Disorders (2016), 200

Major Depressive Disorder (MDD) is a severe and common mental disorder. A growing body of evidence suggests that stepped and/or collaborative care treatment models have several advantages for severely ... [more ▼]

Major Depressive Disorder (MDD) is a severe and common mental disorder. A growing body of evidence suggests that stepped and/or collaborative care treatment models have several advantages for severely depressed patients and caretakers. However, despite the availability of these treatment strategies and guidance initiatives, many depressive patients are solely treated by the general practitioner (GP), and collaborative care is not common. In this paper, we review a selected set of international guidelines to inventory the best strategies for GPs and secondary mental health care providers to collaborate when treating depressed patients. Additionally, we systematically searched the literature, listing potential ways of cooperation, and potentially supporting tools. We conclude that the prevailing guidelines only include few and rather vague directions regarding the cooperation between GPs and specialised mental health practitioners. Inspiring recent studies, however, suggest that relatively little efforts may result in effective collaborative care and a broader implementation of the guidelines in general. [less ▲]

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See detailStatistically Bundled Shewhart Control Charts for Monitoring Delivery Chains Systems
Foster, Earnest; Faraz, Alireza ULg; Heuchenne, Cédric ULg

in European Journal of Industrial Engineering (2016)

Continuous monitoring of Delivery Time variables by means of control charts in a delivery chain is a very recent application of Statistical Process Control (SPC) to the service sector. The aim of the ... [more ▼]

Continuous monitoring of Delivery Time variables by means of control charts in a delivery chain is a very recent application of Statistical Process Control (SPC) to the service sector. The aim of the proposed method is to provide supply chain decision makers with an easy to be managed tool monitoring the current functioning state of the delivery chain. The implementation of SPC control charts makes it possible to limit over-corrections to false alarm conditions and to maintain at an acceptable level the safety stock, with a consequent reduction of the overall management costs of the delivery chain. An illustrative example shows the proposed control chart implementation in a real delivery chain. [less ▲]

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See detailStable biofilms of Rhodococcus erythropolis T902.1 in draining pavement structures for runoff water decontamination
Masy, Thibaut ULg; Bertrand, Christelle ULg; Paul-Marie, Xavier et al

in International Biodeterioration & Biodegradation (2016), 112

Permeable Pavement Systems (PPS) are sustainable devices designed to collect, store and treat urban stormwater before its release into the ground. However, this system must sufficiently retain pollutants ... [more ▼]

Permeable Pavement Systems (PPS) are sustainable devices designed to collect, store and treat urban stormwater before its release into the ground. However, this system must sufficiently retain pollutants brought by water runoff in order to comply with the current legislation. This study aims at evaluating the implementation in PPS of a hydrocarbonoclastic bacterium, Rhodococcus erythropolis T902.1, in terms of resilience and improvement of the degrading capacity. First results revealed that this strain could durably colonize the different gravels used in the construction of PPS. A 15-month experience in a real parking area showed that this biofilm remained viable without any replenishment of nutrients or bacteria. During accelerated pollution tests at a pilot scale, the structure bioaugmented with pre-coated biofilms was more efficient than a non-inoculated structure to limit hydrocarbon leaching below 50 μg L−1 and to degrade hydrocarbons adsorbed to the gravels. Over the long term, this innovative assembly should maintain the degrading capacity of PPS and ensure an effective treatment of stormwater before its infiltration into the soil. [less ▲]

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See detailGuided group purchases of energy renovation services and works in deprived urban neighbourhoods
Ruelle, Christine ULg; Teller, Jacques ULg

in Energy Efficiency (2016), 9(4), 861-874

The energy retrofitting of housings is progressing very slowly in Wallonia (Belgium) despite individual fiscal measures and subsidies offered by public authorities to support households engaging in this ... [more ▼]

The energy retrofitting of housings is progressing very slowly in Wallonia (Belgium) despite individual fiscal measures and subsidies offered by public authorities to support households engaging in this process. This paper explores the use of a method called ‘Guided Group Purchases’ (GPPs), i.e. an approach combining support, guidance and group purchasing of energy renovation services and works, as a possible method to accelerate the retrofitting of the existing housing stock. It reports on an action research experiment conducted in the context of the Interreg project ‘SUN’ (Sustainable Urban Neighbourhoods). The results of this experiment are quite promising. Within a few months, some 80 energy retrofitting interventions (energy audits or insulation works) were implemented in one neighbourhood of the city of Liège. Our evaluation of the experiment showed that the prospect of achieving cost reductions was one of the main initial expectations of participants to the GGPs. Still the participants rather insisted on other benefits after taking part to the initiative. These benefits were mostly related to the guidance they received, to the facilitation with contractors and to the social dynamics generated by the initiative. Several weaknesses were also identified by participants, like the lack of follow-up during and after the works. Our evaluation also highlighted that the main landlords did not participate in the initiative and that the influence of GGPs on costs was limited to specific types of interventions. Despite observed limitations and possible improvements, such a neighbourhood-based approach certainly constitutes a promising avenue for public authorities to support and accelerate the energy retrofitting of private residential buildings in urban neighbourhoods. [less ▲]

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See detailLes supports des images : de la photographie à l’image numérique
Dondero, Maria Giulia ULg; Reyes, Everardo

in Revue Française des Sciences de l'Information et de la Communication (2016), 9

In this article we deal with questions related to images (painting, photography, digital image) from a semiotic standpoint, more precisely the form and substance of their expression plane. Classical ... [more ▼]

In this article we deal with questions related to images (painting, photography, digital image) from a semiotic standpoint, more precisely the form and substance of their expression plane. Classical greimasian semiotics –mainly through the works of Jean-Marie Floch (1985, 1986) and Félix Thürlemann (1982) – has concentrated on the relation between form of expression and form of content (thus in a semi-symbolic fashion). Then, in the 1990s, Jacques Fontanille started exploring the substance of expression. Later, within the framework of hierarchical levels of analysis, Fontanille (2005, 2008), introduced concepts such as material and formal support in order to distinguish between image as object and image as text. We take into account these works to study the close relationship between the substance of expression of images and the practices of production-reception. [less ▲]

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See detailDEM modeling of ball mills with experimental validation: influence of contact parameters on charge motion and power draw
Boemer, Dominik ULg; Ponthot, Jean-Philippe ULg

in Computational Particle Mechanics (2016)

Discrete element method simulations of a 1:5-scale laboratory ball mill are presented in this paper to study the influence of the contact parameters on the charge motion and the power draw. The position ... [more ▼]

Discrete element method simulations of a 1:5-scale laboratory ball mill are presented in this paper to study the influence of the contact parameters on the charge motion and the power draw. The position density limit is introduced as an efficient mathematical tool to describe and to compare the macroscopic charge motion in different scenarios, i.a. with different values of the contact parameters. While the charge motion and the power draw are relatively insensitive to the stiffness and the damping coefficient of the linear spring-slider-damper contact law, the coefficient of friction has a strong influence since it controls the sliding propensity of the charge. Based on the experimental calibration and validation by charge motion photographs and power draw measurements, the descriptive and predictive capabilities of the position density limit and the discrete element method are demonstrated, i.e. the real position of the charge is precisely delimited by the respective position density limit and the power draw can be predicted with an accuracy of about 5 %. [less ▲]

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See detailApports phénoménologiques à l’étude de la relation au corps dans le jeu vidéo
Delbouille, Julie ULg

in Implications philosophiques (2016)

J’évite un obstacle. Je cours. Je saute. Alors que quelques notes de musique m’avertissent de l’échec de ce dernier mouvement, je vois mon corps chuter, happé par le vide au-delà de l’écran. Cette scène ... [more ▼]

J’évite un obstacle. Je cours. Je saute. Alors que quelques notes de musique m’avertissent de l’échec de ce dernier mouvement, je vois mon corps chuter, happé par le vide au-delà de l’écran. Cette scène, qui tout comme ses multiples variations s’inscrit en filigrane au cœur de nombreuses expériences vidéoludiques, soulève la question du rapport au corps dans le jeu vidéo. Dans le champ des Game et des Play Studies, nombreux sont les chercheurs qui se sont déjà emparés de l’interactivité comme objet d’étude, et d’une de ses modalités dans le jeu vidéo : l’avatar. Interface récurrente entre le joueur et l’univers vidéoludique, nous postulons que cette « enveloppe pilotable » constitue une porte d’entrée pour envisager la problématique corporelle dans le jeu vidéo. En effet, la fonction d’incarnation permise par l’avatar ajoute à la relation entre le corps et l’esprit du joueur une dimension nouvelle : celle du corps virtuel. Ce corps « autre », dont le joueur prend possession, constitue une des conditions de son « insertion » dans le monde du jeu. [less ▲]

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See detailHCOOH distributions from IASI for 2008-2014: comparison with ground-based FTIR measurements and a global chemistry-transport model
Pommier, M.; Clerbaux, C.; Coheur, P.-F. et al

in Atmospheric Chemistry and Physics (2016), 16

Formic acid (HCOOH) is one of the most abundant volatile organic compounds in the atmosphere. It is a major contributor to rain acidity in remote areas. There are, however, large uncertainties on the ... [more ▼]

Formic acid (HCOOH) is one of the most abundant volatile organic compounds in the atmosphere. It is a major contributor to rain acidity in remote areas. There are, however, large uncertainties on the sources and sinks of HCOOH and therefore HCOOH is misrepresented by global chemistry-transport models. This work presents global distributions from 2008 to 2014 as derived from the measurements of the Infrared Atmospheric Sounding Interferometer (IASI), based on conversion factors between brightness temperature differences and representative retrieved total columns over seven regions: Northern Africa, southern Africa, Amazonia, Atlantic, Australia, Pacific, and Russia. The dependence of the measured HCOOH signal on the thermal contrast is taken into account in the conversion method. This conversion presents errors lower than 20 % for total columns ranging between 0.5 and 1 × 1016 molec/cm2 but reaches higher values, up to 78 %, for columns that are lower than 0.3 × 1016 molec/cm2. Signatures from biomass burning events are highlighted, such as in the Southern Hemisphere and in Russia, as well as biogenic emission sources, e.g., over the eastern USA. A comparison between 2008 and 2014 with ground-based Fourier transform infrared spectroscopy (FTIR) measurements obtained at four locations (Maido and Saint-Denis at La Réunion, Jungfraujoch, and Wollongong) is shown. Although IASI columns are found to correlate well with FTIR data, a large bias (> 100 %) is found over the two sites at La Réunion. A better agreement is found at Wollongong with a negligible bias. The comparison also highlights the difficulty of retrieving total columns from IASI measurements over mountainous regions such as Jungfraujoch. A comparison of the retrieved columns with the global chemistry-transport model IMAGESv2 is also presented, showing good representation of the seasonal and interannual cycles over America, Australia, Asia, and Siberia. A global model underestimation of the distribution and a misrepresentation of the seasonal cycle over India are also found. A small positive trend in the IASI columns is observed over Australia, Amazonia, and India over the 2008–2014 period (from 0.7 to 1.5 %/year), while a decrease of ∼ 0.8 %/year is measured over Siberia. [less ▲]

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See detailLa biodiversité entomologique comme source d’aliments à Kinshasa (République démocratique du Congo)
Nsevolo, Papy; Alabi, Taofic ULg; Caparros Megido, Rudy ULg et al

in Annales de la Société Entomologique de France (2016)

L’exploitation des produits forestiers non ligneux dont notamment les insectes comestibles jouent un rôle important dans les habitudes alimentaires et économies locales des populations autochtones du ... [more ▼]

L’exploitation des produits forestiers non ligneux dont notamment les insectes comestibles jouent un rôle important dans les habitudes alimentaires et économies locales des populations autochtones du bassin du Congo. Bien que la consommation d’insectes en République Démocratique du Congo soit une pratique ancienne, l’inventaire et l’identification taxonomique des espèces consommées ainsi que la caractérisation de la filière « entomophagie » sont encore mal maitrisés. Toutefois, nos études axées sur la ville de Kinshasa ont permis d’inventorier 14 espèces comestibles régulièrement consommées. Elles appartiennent à l’ordre des Lépidoptères (46,7%), des Isoptères (18,6%), des Orthoptères (17,6%), des Coléoptères (9,7%) et des Hyménoptères (3,7%). De façon générale, 80% de la population de Kinshasa consomment au minimum une espèce d’insecte 5 jours par mois avec des quantités variant de 66,4 à 154 g d’insectes par personne par jour en fonction des différents ordres. Les acteurs de la filière sont majoritairement des femmes. Les revenus générés par l’activité concourent au bien-être des ménages, à la réduction de la pauvreté et de l’insécurité alimentaire dans de la capitale Kinshasa. [less ▲]

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See detailFirst characterization and validation of FORLI-HNO3 vertical profiles retrieved from IASI/Metop
Ronsmans, G.; Langerock, B.; Wespes, C. et al

in Atmospheric Measurement Techniques. Papers in Open Discussion (2016), 2016

Knowing the spatial and seasonal distributions of nitric acid (HNO3) around the globe is of great interest to apprehend the processes regulating stratospheric ozone, especially in the polar regions ... [more ▼]

Knowing the spatial and seasonal distributions of nitric acid (HNO3) around the globe is of great interest to apprehend the processes regulating stratospheric ozone, especially in the polar regions. Thanks to its unprecedented spatial and temporal sampling, the nadir-viewing Infrared Atmospheric Sounding Interferometer (IASI) allows sounding the atmosphere twice a day globally, with good spectral resolution and low noise. With the Fast Optimal Retrievals on Layers for IASI (FORLI) algorithm, we are retrieving, in near-real time, columns as well as vertical profiles of several atmospheric species, amongst which is HNO3. We present in this paper the first characterization of the FORLI-HNO3 profile products, in terms of vertical sensitivity and error budgets. We show that the sensitivity of IASI to HNO3 is highest in the lower stratosphere (10–20km), where the largest amounts of HNO3 are found, but that the vertical sensitivity of IASI only allows one level of information on the profile (DOFS 1). The sensitivity near the surface is negligible in most cases, and for this reason, a partial column (5–35km) is used for the analyses. Both vertical profiles and partial columns are compared to FTIR ground-based measurements from the Network for the Detection of Atmospheric Composition Change (NDACC) to characterize the accuracy and precision of the FORLI-HNO3 product. The profile validation is conducted through the smoothing of the raw FTIR profiles by the IASI averaging kernels and gives good results, with a slight overestimation of IASI measurements in the Upper Troposphere-Lower Stratosphere (UTLS) at the 6 chosen stations (Thule, Kiruna, Jungfraujoch, Izaña, Lauder and Arrival Heights). The validation of the partial columns (5–35km) is also conclusive with a mean correlation of 0.93 between IASI and the FTIR measurements. An initial survey of the HNO3 spatial and seasonal variabilities obtained from IASI measurements for a one year (2011) data set shows that the expected latitudinal gradient of concentrations from low to high latitudes and the large seasonal variability in polar regions (cycle amplitude around 30% of the seasonal signal, peak-to-peak) are well represented with IASI data. [less ▲]

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See detailAzacytidine mitigates experimental sclerodermic graft-versus-host disease
Fransolet, Gilles ULg; Ehx, Grégory ULg; SOMJA, Joan ULg et al

in Journal of Hematology & Oncology (2016)

Background Previous studies have demonstrated that regulatory T cells (Tregs) play a protective role in the pathogenesis of chronic graft-versus-host disease (cGVHD). Tregs constitutively express the gene ... [more ▼]

Background Previous studies have demonstrated that regulatory T cells (Tregs) play a protective role in the pathogenesis of chronic graft-versus-host disease (cGVHD). Tregs constitutively express the gene of the transcription factor Foxp3 whose CNS2 region is heavily methylated in conventional CD4+ T cells (CD4+Tconvs) but demethylated in Tregs. Methods Here, we assessed the impact of azacytidine (AZA) on cGVHD in a well-established murine model of sclerodermic cGVHD (B10.D2 (H-2d) → BALB/cJ (H-2d)). Results The administration of AZA every 48 h from day +10 to day +30 at the dose of 0.5 mg/kg or 2 mg/kg mitigated chronic GVHD. Further, AZA-treated mice exhibited higher blood and thymic Treg frequencies on day +35, as well as higher demethylation levels of the Foxp3 enhancer and the IL-2 promoter in splenocytes at day +52. Interestingly, Tregs from AZA-treated mice expressed more frequently the activation marker CD103 on day +52. AZA-treated mice had also lower counts of CD4+Tconvs and CD8+ T cells from day +21 to day +35 after transplantation, as well as a lower proportion of CD4+Tconvs expressing the Ki67 antigen on day +21 demonstrating an anti-proliferating effect of the drug on T cells. Conclusions Our results indicate that AZA prevented sclerodermic cGVHD in a well-established murine model of cGVHD. These data might serve as the basis for a pilot study of AZA administration for cGVHD prevention in patients at high risk for cGVHD. [less ▲]

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See detailDémographie et performances zootechniques des élevages bovins traditionnels au Nord Bénin
Chabi Toko, Roukayath ULg; Adégbidi, Anselme; Lebailly, Philippe ULg

in Revue d'Elévage et de Médecine Vétérinaire des Pays Tropicaux (2016), 69(1), 33-39

The study was conducted with 150 Fulani herders in the departments of Borgu and Alibori in Benin. It aimed to determine the zootechnical parameters of traditional cattle farms. The survey collected ... [more ▼]

The study was conducted with 150 Fulani herders in the departments of Borgu and Alibori in Benin. It aimed to determine the zootechnical parameters of traditional cattle farms. The survey collected information on the characteristics of cattle herds. The results showed a high proportion of females (76%), an average herd size (66 animals) and the prevalence of the Borgu breed (86%). The herds also showed a low breeding performance, characterized by a high calf mortality rate (10%), and low reproductive parameters (64% calving and fertility rates). In a year, 0.57 calf was weaned on average by its dam. The low performance of cattle farms in coastal countries such as Benin is consistent with that of pastoral areas, which is complementary in terms of meat supply to West African markets. [less ▲]

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See detailAsymptotic properties of free monoid morphisms
Charlier, Emilie ULg; Leroy, Julien ULg; Rigo, Michel ULg

in Linear Algebra & its Applications (2016), 500

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See detailDynamics of a thin radial liquid flow
De Cock, Nicolas ULg; Massinon, Mathieu ULg; Ouled Taleb Salah, Sofiene ULg et al

in Fire Safety Journal (2016), 83

The present work proposes an extension of the existing analytical development on the radial spread of a liquid jet over a horizontal surface to the case of a thin radial flow. When the gap, H, between the ... [more ▼]

The present work proposes an extension of the existing analytical development on the radial spread of a liquid jet over a horizontal surface to the case of a thin radial flow. When the gap, H, between the jet nozzle and the plate is reduced the discharging area may be smaller than the inlet area leading to an increase of the main flow velocity downstream of the thin cylindrical opening. This increase of velocity, de fined here as 1/alpha , can be related to the relative gap of the nozzle H/R with R the nozzle pipe radius. Numerical computations with a volume of fluid method were realised with for H/R ranging from 0.2 to 3 and with flow rates Q of 3 and 6 l/min1. The results of these computations allowed to express alpha in respect of H/R. Taking in account the flow acceleration allowed to extend the set of equation from the jet impacting flow to the thin cylindrical opening flow. The liquid layer thickness and the surface velocity diff er with a maximum error of 4% between the flow predicted by the model and computations. Main discrepancies appear in the region close to the nozzle where the analytical model assumption of a constant velocity outside the boundary layer is not valid. However, further downstream the model and the computations are in good agreement. [less ▲]

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See detailPoor Performance of a Retrofitted Downstream Bypass Revealed by the Analysis of Approaching Behaviour in Combination with a Trapping System
Ovidio, Michaël ULg; Dierckx, Arnaud ULg; Bunel, Sarah et al

in River Research & Applications (2016), DOI: 10.1002/rra.3062

The implementation of fish downstream migration bypass systems is still a major challenge, and there is interest in validating the adequacy of different configurations of bypass devices. In the Amblève ... [more ▼]

The implementation of fish downstream migration bypass systems is still a major challenge, and there is interest in validating the adequacy of different configurations of bypass devices. In the Amblève River (Belgium), a mobile 3.3-m height dam feeds two principal Francis and one Francis micro-turbine and is equipped with a modern vertical slot fish pass and a downstream bypass. The aim of this study was to test the bypass attraction and efficiency (i.e. percentage of fish that approach the entrance and use the bypass) for Atlantic salmon smolts. During three consecutive years, a total of 1346 smolts were equipped with a radio frequency identification tag and released from March to May upstream of the dam of Lorcé. The entrance of the downstream migration bypass was equipped with a radio frequency identification antenna in order to detect the smolts approaching. In 2014, a capture cage was also placed downstream the bypass to evaluate its efficiency. The mean percentage of detected smolts at the entrance varied from 26.2 to 39.7%. In 2014, 16.5% of the released smolts entered the bypass and were finally caught in the cage, representing 39% of the smolts detected at the entrance. More than 98% of the detections occurred during night (mainly between 9 PM and 3 AM). The searching delay near the bypass entrance varied from less than 5 min to more than 5 days (median 4.3 min). Visual observation indicated a behavioural reluctance before entering the bypass, with a shift from positive to negative rheotaxy. Our results underline the difficulty to install retrofitted bypass system on old existing hydropower plants. Copyright © 2016 John Wiley & Sons, Ltd. [less ▲]

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See detailEuropean Commission, trade agreements, and diversity of cultural expressions: between autonomy and influence
Vlassis, Antonios ULg

in European Journal of Communication (2016)

The Convention on diversity of cultural expressions – adopted by United Nations Educational, Scientific and Cultural Organization in 2005 – is a main international instrument within the global governance ... [more ▼]

The Convention on diversity of cultural expressions – adopted by United Nations Educational, Scientific and Cultural Organization in 2005 – is a main international instrument within the global governance of cultural and audiovisual industries. For its part, the European Commission played a critical role in the negotiation, leading to the Convention on Diversity of Cultural Expressions’ adoption. In this respect, the article aims to explore why and how the Commission uses the Convention on Diversity of Cultural Expressions throughout the recent European Union trade negotiations, for which purposes and how the Convention on Diversity of Cultural Expressions influences the European Union foreign policy and its objectives. The article is more concerned with analysing the policy process through which the Commission’s strategy is formulated in light of the Convention on Diversity of Cultural Expressions and of the place of cultural and audiovisual industries within the European Union trade agreements and also concerned with understanding whether the Commission’s autonomy is transformed into influence within the policy process. [less ▲]

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See detailEnonciation et modes d'existence
Dondero, Maria Giulia ULg

in Nouveaux Actes Sémiotiques (2016)

Cet article aborde les relations entre sémiotique et philosophie latourienne à partir de la théorie de l’énonciation, cette dernière se situant tant aux fondements du projet disciplinaire de la sémiotique ... [more ▼]

Cet article aborde les relations entre sémiotique et philosophie latourienne à partir de la théorie de l’énonciation, cette dernière se situant tant aux fondements du projet disciplinaire de la sémiotique francophone contemporaine qu’à la base de la réflexion de Bruno Latour, des années 1970 jusqu’à présent . Notre propos se déploie en deux moments : dans un premier temps, nous revenons sur l’article "Petite Philosophie de l’énonciation" (1998), et nous en suivons le développement dans l’Enquête sur les modes d’existence (2012). Dans un second temps, nous réalisons une rapide archéologie de la théorie de l’énonciation dans la sémiotique contemporaine, afin de mettre en lumière les liens entre différentes traditions sémiotiques et la théorie latourienne. Plus précisément, nous nous attachons aux propositions récentes de Jacques Fontanille et de Claudio Paolucci, en prenant également en considération les contributions d’Umberto Eco et Patrizia Violi. Il s’agit de voir comment les sémioticiens peuvent tirer profit de la théorie latourienne des modes d’existence et vice versa. [less ▲]

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See detailEstimating the out-of-sample predictive ability of trading rules: a robust bootstrap approach
Hambuckers, julien ULg; Heuchenne, Cédric ULg

in Journal of Forecasting (2016), 35(4), 347-372

In this paper, we provide a novel way to estimate the out-of-sample predictive ability of a trading rule. Usually, this ability is estimated using a sample splitting scheme, true out-of-sample data being ... [more ▼]

In this paper, we provide a novel way to estimate the out-of-sample predictive ability of a trading rule. Usually, this ability is estimated using a sample splitting scheme, true out-of-sample data being rarely available. We argue that this method makes a poor use of the available data and creates data mining possibilities. Instead, we introduce an alternative .632 bootstrap approach. This method enables to build in- sample and out-of-sample bootstrap datasets that do not overlap but exhibit the same time dependencies. We show in a simulation study that this technique drastically reduces the mean squared error of the estimated predictive ability. We illustrate our methodology on IBM, MSFT and DJIA stock prices, where we compare 11 trading rules speci cations. For the considered datasets, two different filter rule specifications have the highest out-of-sample mean excess returns. However, all tested rules cannot beat a simple buy-and-hold strategy when trading at a daily frequency. [less ▲]

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See detailEntretien avec Michel Dumoulin. Regards sur les mondes de la recherche et de l'histoire.
Genin, Vincent ULg

in Contemporanea (2016), XXXVIII(2),

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See detailAnionic flow polymerizations toward functional polyphosphoesters in microreactors: Polymerization and UV-modification
Baeten, Evelien; Vanslambrouck, Stéphanie; Jérôme, Christine ULg et al

in European Polymer Journal (2016), 80

The polymerization of cyclic phosphates to poly(phosphoester)s, PPEs, is optimized for chip- based microreactors under continuous flow conditions. The anionic ring-opening polymerization of 2-isobutyoxy-2 ... [more ▼]

The polymerization of cyclic phosphates to poly(phosphoester)s, PPEs, is optimized for chip- based microreactors under continuous flow conditions. The anionic ring-opening polymerization of 2-isobutyoxy-2-oxo-1,3,2-dioxaphospholane (iBP) via the use of two organocatalytic systems allowed to polymerize to nearly quantitative monomer conversion within 10 or 3 minutes, respectively at a reaction temperature of 40 °C. Further, the optimized polymerization protocol was applied to 2-butenoxy-2-oxo-1,3,2-dioxaphospholane (BP) which yields a polymer that carries an alkene functionality per monomer repeating unit. This material can be postmodified in an UV-induced radical thiol-ene reaction, which was also shown to proceed with very high efficiency under UV-flow conditions. Eventually, both reactions were coupled in a two-stage reactor setup, showing that the thermally-activated polymerization can be coupled with high efficiency to the UV-activated post-polymerization modification reaction. The introduced reactor setup can in the future be used to produce and screen a broad variety of functional PPE materials with various functionalities and physical properties. [less ▲]

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See detailCapillary electrophoresis method to determine siRNA complexation with cationic liposomes
Furst, Tania ULg; Bettonville, Virginie ULg; Farcas, Elena ULg et al

in Electrophoresis (2016)

Small interfering RNA (siRNA) inducing gene silencing has great potential to treat many human diseases. To ensure effective siRNA delivery, it must be complexed with an appropriate vector, generally ... [more ▼]

Small interfering RNA (siRNA) inducing gene silencing has great potential to treat many human diseases. To ensure effective siRNA delivery, it must be complexed with an appropriate vector, generally nanoparticles. The nanoparticulate complex requires an optimal physiochemical characterization and the complexation efficiency has to be precisely determined. The methods usually used to measure complexation are gel electrophoresis and RiboGreen® fluorescence-based assay. However, those approaches are not automated and present some drawbacks such as the low throughput and the use of carcinogenic reagents. The aim of this work is to develop a new simple and fast method to accurately quantify the complexation efficiency. In this research, capillary electrophoresis (CE) was used to determine the siRNA complexation with cationic liposomes. The short-end injection mode applied enabled siRNA detection in less than 5 min. Moreover, the CE technique offers many advantages compared to the other classical methods. It is automated, does not require sample preparation and expensive reagents. Moreover, no mutagenic risk is associated to CE approach since no carcinogenic product is used. Finally, this methodology can also be extended to the characterization of other types of nanoparticles encapsulating siRNA, such as cationic polymeric nanoparticles. [less ▲]

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See detailLes mustères de la "Viege noire" ou comment se passe la demande d'allocation de handicap
Marquet, Françoise; RADERMECKER, Régis ULg

in Revue de l'Association Belge du Diabète (2016), 59(4), 9-13

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See detailBoosting shape classifiers accuracy by considering the inverse shape
Pierard, Sébastien ULg; Lejeune, Antoine ULg; Van Droogenbroeck, Marc ULg

in Journal of Pattern Recognition Research (2016), 11(1), 41-54

Many techniques exist for describing shapes. These techniques almost exclusively consider the contour or the inside of the shape; the major problem for describing the outside of a shape, or inverse shape ... [more ▼]

Many techniques exist for describing shapes. These techniques almost exclusively consider the contour or the inside of the shape; the major problem for describing the outside of a shape, or inverse shape, being that it has an infinite extension. In this paper, we show how to adapt two shape descriptors, one region based, the Cover By Rectangles, and one transform based, the Zernike moments, to be applicable to the inverse shape. We analyze their properties, and show how to deal with the infinite extension of the inverse shape. Then, we apply these descriptors to shape classification and compare representations that use the shape, its inverse, or both. Our experiments establish that, for shape classification, a representation integrating the inverse shape often outperforms a representation restricted to the shape. This opens the path for better techniques that could use, as a rule of thumb, both the representations of a shape and its inverse for the purpose of classification. [less ▲]

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See detailAnalysis of SMOS sea surface salinity data using DINEOF
Alvera Azcarate, Aïda ULg; Barth, Alexander ULg; Parard, Gaëlle ULg et al

in Remote Sensing of Environment (2016), 180

n analysis of daily Sea Surface Salinity (SSS) at 0.15 ° × 0.15° spatial resolution from the Soil Moisture and Ocean Salinity (SMOS) satellite mission using DINEOF (Data Interpolating Empirical Orthogonal ... [more ▼]

n analysis of daily Sea Surface Salinity (SSS) at 0.15 ° × 0.15° spatial resolution from the Soil Moisture and Ocean Salinity (SMOS) satellite mission using DINEOF (Data Interpolating Empirical Orthogonal Functions) is presented. DINEOF allows reconstructing missing data using a truncated EOF basis, while reducing the amount of noise and errors in geophysical datasets. This work represents a first application of DINEOF to SMOS SSS. Results show that a reduction of the error and the amount of noise is obtained in the DINEOF SSS data compared to the initial SMOS SSS data. Errors associated to the edge of the swath are detected in 2 EOFs and effectively removed from the final data, avoiding removing the data at the edges of the swath in the initial dataset. The final dataset presents a centered root mean square error of 0.2 in open waters when comparing with thermosalinograph data at their original spatial and temporal resolution. Constant biases present near land masses, large scale biases and latitudinal biases cannot be corrected with DINEOF because persistent signals are retained in high order EOFs, and therefore these need to be corrected separately. The signature of the Douro and Gironde rivers is detected in the DINEOF SSS. The minimum SSS observed in the Gironde plume corresponds to a flood event in June 2013, and the shape and size of the Douro river shows a good agreement with chlorophyll-a satellite data. These examples show the capacity of DINEOF to remove noise and provide a full SSS dataset at a high temporal and spatial resolution with reduced error, and the possibility to retrieve physical signals in zones with high initial errors. [less ▲]

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See detailPlant mitochondrial complex I composition and assembly: a review
Subrahmanian, Nitya; Remacle, Claire ULg; Hamel, Patrice

in Biochimica et Biophysica Acta-Bioenergetics (2016), 1857(7), 1001-1014

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See detailQuand Caïn scrute Abel. Reflets mutuels des neutralités belge et suisse autour de la Première Guerre mondiale
Genin, Vincent ULg

in Revue Générale (2016), 2016/4(juillet-août),

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See detailLes puissances émergentes dans la bataille mondiale de l'attraction: Bollywood, vecteur du soft power de l'Inde?
Vlassis, Antonios ULg

in Interventions Economiques = Papers in Political Economy (2016), 55(July),

This article deals with the importance of the Indian film industry for the strengthening of India’s soft power and with the capability of the country to build an international status of active cultural ... [more ▼]

This article deals with the importance of the Indian film industry for the strengthening of India’s soft power and with the capability of the country to build an international status of active cultural power. As such, on the one hand, I seek to analyze the institutional features of the Indian movie system and to focus on the role of India within the international regime for audiovisual sector, and on the other hand, I aim to emphasize the worldwide cultural competition that India faces. The findings will show that the domestic structures are a major factor in order to understand the influence of India and its status within the world audiovisual economy, within which Hollywood has highly financing abilities and global distribution strategies. [less ▲]

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See detailCyclin-dependent protein kinase inhibitors in breast cancer treatment
FRERES, Pierre ULg; LOUSBERG, Laurence ULg; JERUSALEM, Guy ULg

in Belgian Journal of Medical Oncology [=BJMO] (2016), 10(4), 132-138

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See detailMulti-species measurements of nitrogen isotopic composition reveal the spatial constraints and biological drivers of ammonium attenuation across a highly contaminated groundwater system
Wells, Naomi S.; Hakoun, Vivien ULg; Brouyère, Serge ULg et al

in Water Research (2016), 98

Groundwater under industrial sites is characterised by heterogeneous chemical mixtures, making it difficult to assess the fate and transport of individual contaminants. Quantifying the in-situ biological ... [more ▼]

Groundwater under industrial sites is characterised by heterogeneous chemical mixtures, making it difficult to assess the fate and transport of individual contaminants. Quantifying the in-situ biological removal (attenuation) of nitrogen (N) is particularly difficult due to its reactivity and ubiquity. Here a multi-isotope approach is developed to distinguish N sources and sinks within groundwater affected by complex industrial pollution. Samples were collected from 70 wells across the two aquifers underlying a historic industrial area in Belgium. Below the industrial site the groundwater contained up to 1000 mg Nl-1 ammonium (NH4 +) and 300 mg N l-1 nitrate (NO3-), while downgradient concentrations decreased to ~1 mg l-1 DIN ([DIN] = [NH4+-N] + [NO3--N] + [NO2--N]). Mean δ1534 N-DIN increased from ~2‰ to +20‰ over this flow path, broadly confirming that biological N attenuation drove the measured concentration decrease. Multi-variate analysis of water chemistry identified two distinct NH4+ sources (δ15N-NH4+ from -14‰ and +5‰) within the contaminated zone of both aquifers. Nitrate dual isotopes co-varied (δ15 N: -3‰ - +60‰; δ18O: 0‰ - +50‰) within the range expected for coupled nitrification and denitrification of the identified sources. The fact that δ15N-NO2- values were 50‰ to 20‰ less than δ15N-NH4+ values in 40 the majority of wells confirmed that nitrification controlled N turnover across the site. However, the fact that δ15N-NO2- was greater than δ15N-NH4+ in wells with the highest [NH4+] shows that an autotrophic NO2- reduction pathway (anaerobic NH4+ oxidation or nitrifier-denitrification) drove N attenuation closest to the contaminant plume. This direct empirical evidence that both autotrophic and heterotrophic biogeochemical processes drive N attenuation in contaminated aquifers demonstrates the power of multiple N isotopes to untangle N cycling in highly complex systems. [less ▲]

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See detailTopology optimization for minimum weight with compliance and simpli ed nominal stress constraints for fatigue resistance
Collet, Maxime ULg; Bruggi, Matteo; Duysinx, Pierre ULg

in Structural and Multidisciplinary Optimization (2016)

This work investigates a simpli ed approach to cope with the optimization of preliminary design of structures under local fatigue constraints along with a global enforcement on the overall compliance. The ... [more ▼]

This work investigates a simpli ed approach to cope with the optimization of preliminary design of structures under local fatigue constraints along with a global enforcement on the overall compliance. The problem aims at the minimization of the weight of linear elastic structures under given loads and boundary conditions. The expected sti ness of the optimal structure is provided by the global constraint, whereas a set of local stress-based constraints ask for a structure to be fatigue resistant. A modi ed Goodman fatigue strength comparison is implemented through the same formalism to address pressure-dépendent failure in materials as in Drucker-Prager strength criterion. As a simplification, the Sines approach is used to de ne the equivalent mean and alternating stresses to address the fatigue resistance for an infinite life time. Sines computation is based on the equivalent mean and alternate stress depending on the invariants of the stress tensor and itsdeviatoric part, respectively. The so-called singularity phenomenon is overcome by the implementation of a suitable qp-relaxation of the equivalent stress measures. Numerical examples are presented to illustrate the features of the achieved optimal layouts and of the proposed algorithm. [less ▲]

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See detailMontage et résistance du réel chez S. Kracauer : Photographie, cinéma, texte
Hagelstein, Maud ULg; Hamers, Jérémy ULg

in Bulletin d'Analyse Phénoménologique (2016), 12 (2016)(4),

En tant que témoin et acteur des vifs débats sur le montage qui marquent l’Europe artistique et intellectuelle de l’après-guerre, Kracauer rédige dans les années 1920 une série de « feuilletons » sur la ... [more ▼]

En tant que témoin et acteur des vifs débats sur le montage qui marquent l’Europe artistique et intellectuelle de l’après-guerre, Kracauer rédige dans les années 1920 une série de « feuilletons » sur la modernité weimarienne repris dans L’Ornement de la masse (1963). Un texte en particulier retiendra ici notre attention qui permet de poser, en dehors des analyses vouées au cinéma, la question du montage. Ce texte, « Le Hall d’hôtel », est extrait d’un ouvrage sur le roman policier non publié à l’époque. Il vise à énoncer le problème du sens dans une société où la religion s’effondre progressivement. Selon Kracauer, la production artistique est toute entière prise dans cette vocation de solutionner la perte de sens consécutive à la modernité. Comme il l’évoque en des termes apparemment naïfs, plus le monde se déréalise, plus l’art doit exercer son rôle d’éducateur2. Là où le monde est devenu muet, là où son sens général s’est obscurci, la forme esthétique peut encore produire selon Kracauer une « sorte de langage ». L’art permet en effet d’exprimer à nouveaux frais les relations existant entre des éléments décousus et « reposant les uns à côté des autres en ordre dispersé ». Vecteur d’une sortie de l’état désenchanté du monde moderne, l’éducateur se définit par conséquent chez Kracauer comme celui qui relie entre eux des éléments épars. Et l’artiste devient bien un tel éducateur lorsqu’il vise, à travers un « organisme esthétique », une totalité qui permet de ressaisir les « éléments d’un monde en décomposition dispersés à l’aveuglette »3. Or, dans ce texte de jeunesse déjà, Kracauer introduit une nuance : car si le rôle de l’artiste est déterminant dans sa tentative de résoudre le désenchantement du monde, il risque aussi de s’engager sur la voie néfaste qui consisterait à ré-enchanter le monde de manière abusive. Face à ces éléments dispersés qu’il s’agit de réorganiser, l’artiste peut soit être un véritable éducateur-voyant et restituer avec justesse les liens entre les éléments (il est alors du côté du « bon » montage qui respecte la réalité), soit construire un monde totalement artificiel, potentiellement enclin à donner une idée fausse de la réalité, voire idéologiquement trompeuse, en somme une sorte de « mauvais » montage. Kracauer se méfiera jusqu’à la fin de sa vie de ce montage-là, sans cependant jamais définir précisément le « principe de réalité » auquel s’adosse la normativité établie par lui comme fondement de toute l’esthétique matérielle. [less ▲]

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See detailA simple calibration approach based on film-casting for confocal Raman microscopy to support the development of a Hot-Melt Extrusion process
Netchacovitch, Lauranne ULg; Thiry, Justine ULg; De Bleye, Charlotte ULg et al

in Talanta (2016), 154

When developing a new formulation, the development, calibration and validation steps of analytical methods based on vibrational spectroscopy are time-consuming. For each new formulation, real samples must ... [more ▼]

When developing a new formulation, the development, calibration and validation steps of analytical methods based on vibrational spectroscopy are time-consuming. For each new formulation, real samples must be produced and a “reference method” must be used in order to determine the Active Pharmaceutical Ingredient (API) content of each sample. To circumvent this issue, the paper presents a simple approach based on the film-casting technique used as a calibration tool in the framework of hot-melt extrusion process. Confocal Raman microscopic method was successfully validated for the determination of itraconazole content in film-casting samples. Then, hot-melt extrusion was carried out to produce real samples in order to confront the results obtained with confocal Raman microscopy and Ultra High Performance Liquid Chromatography (UHPLC). The agreement between both methods was demonstrated using a comparison study based on the Bland and Altman’s plot. [less ▲]

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See detailPerformance et Innovation en PME: une relation à questionner
Ajzen, Michel; Rondeaux, Giseline ULg; Pichault, François ULg et al

in Revue Internationale P.M.E. (2016), 29(2),

Noting that in management science, management policies would have all, the ultimate ambition of contributing to company performance and the innovative capacity of a company would be a sine qua non of this ... [more ▼]

Noting that in management science, management policies would have all, the ultimate ambition of contributing to company performance and the innovative capacity of a company would be a sine qua non of this performance, this article shows that (if) these two concepts refer to disparate content; (ii) the performance is primarily measured by distanced indicators (financial); (iii) the nature of the interdependence between innovation and performance is not unequivocal. Considering the weight of contextual variables, we show the interest to adopt a broader vision of concepts of innovation and performance in SMEs, capitalizing on the diversity of performance and innovation characterizations, and adopting an agnostic approach establishing no a priori link between them. This article proposes to broaden the concepts of innovation and performance by mobilizing indicators specific to SMEs and outlines a methodology to measure and weigh them as well as to provide researchers with tools to better understand the interactions between these variables. In doing so, we contribute to a critical approach of de-naturalization to emancipate SMEs and, more broadly, public and regulatory authorities, from narrow performative standards. [less ▲]

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See detailSoyons optimistes
RADERMECKER, Régis ULg

in Revue de l'Association Belge du Diabète (2016), 59(4), 3

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See detailTemporal habitat shift of a polymorphic newt species under predation risk
Winandy, Laurane ULg; Colin, Mélanie; Denoël, Mathieu ULg

in Behavioral Ecology (2016), 27(4), 1025-1032

The temporal partitioning hypothesis suggests that the evolution of different diel activity rhythms in animals might facilitate the coexistence between prey and predators. However, the temporal shift of ... [more ▼]

The temporal partitioning hypothesis suggests that the evolution of different diel activity rhythms in animals might facilitate the coexistence between prey and predators. However, the temporal shift of habitat use induced by predation has rarely been observed. The study of such a mechanism is particularly relevant for introduced species because it might explain how native species can persist or decline in response to the presence of alien species. The introduction of fish into ponds inhabited by amphibians has severe consequences for their occurrence and abundance. Fish particularly affect an alternative newt phenotype, the paedomorph, which does not undergo metamorphosis and maintains larval traits such as gills at the adult stage. In a laboratory design, we assessed the diel patterns of habitat use in the 2 distinct morphological phenotypes of palmate newt (Lissotriton helveticus) in the presence or absence of goldfish (Carassius auratus). Both newt phenotypes avoided a risky habitat more in the presence than in the absence of fish. This habitat shift was more pronounced during the daytime (i.e., when the risk could be considered higher for the newts) than during nighttime. However, in contrast to metamorphs, paedomorphs showed less adaptive changes according to temporal risk and remained in their shelter for most of the time. Temporal and habitat partitioning at the diel scale between native and alien species might promote their coexistence, but diel change can also imply a cost in the overall reduction of the time allocated to essential activities, showing that species interactions remain complex. [less ▲]

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See detailLe rôle des pays émergents dans la gouvernance économique mondiale
Wintgens, Sophie ULg; Zacharie, Arnaud ULg

in Annuaire français de Relations internationales (2016), XVII(2016),

Since the 2000s, the rising power of emerging countries – China, East Asian countries and the BRICS in particular – changed the balance of power within the system of global economic governance. In an ... [more ▼]

Since the 2000s, the rising power of emerging countries – China, East Asian countries and the BRICS in particular – changed the balance of power within the system of global economic governance. In an increasingly multipolar world, external policies of the main emerging countries are aimed more at legitimizing their status of regional powers rather than at promoting a truly democratic multilateralism. By doing so, the global shift in wealth puts the multilateralism to the test. Although emerging countries have claimed more room in the international economic organizations, many of their demands have not been heard by the Western traditional powers, which prompted them to launch their own initiatives. This creates an increasing fragmentation of international financial and trade rules, which makes more complex the political conditions for effectively regulate the international system. Although emerging countries have contributed to challenge the legitimacy of the global economic governance architecture, they have so far failed to change its nature or to make it more consistent. [less ▲]

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See detailSafety of Everolimus Plus Exemestane In Patients With Hormone-Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer Progressing on Prior Non-Steroidal Aromatase Inhibitors: Primary Results of a Phase 3b, Open-Label, Single-Arm, Expanded-Access Multicenter Trial (BALLET).
Jerusalem, Guy ULg; Mariani, G.; Ciruelos, E. M. et al

in Annals of oncology : official journal of the European Society for Medical Oncology / ESMO (2016)

BACKGROUND: This European phase 3b, expanded-access multicenter trial evaluated the safety of EVE plus EXE in a patient population similar to BOLERO-2. PATIENTS AND METHODS: Postmenopausal women aged (3 ... [more ▼]

BACKGROUND: This European phase 3b, expanded-access multicenter trial evaluated the safety of EVE plus EXE in a patient population similar to BOLERO-2. PATIENTS AND METHODS: Postmenopausal women aged (3)18 years with hormone receptor-positive, human epidermal growth factor-receptor-2-negative advanced breast cancer (ABC) recurring/progressing during/after prior non-steroidal aromatase inhibitors (NSAIs) were enrolled. Primary objective was safety of EVE plus EXE based on frequency of adverse events (AEs), and serious AEs (SAEs). Secondary objective was to evaluate AEs of grade 3/4 severity. RESULTS: Median treatment duration was 5.1 months (95% CI, 4.8-5.6) for EVE and 5.3 months (95% CI, 4.8-5.6) for EXE. Overall, 2131 patients were included in the analysis; 81.8% of patients experienced EVE- or EXE-related or EVE/EXE-related AEs (investigator assessed); 27.2% were of grade 3/4 severity. The most frequently reported non-hematologic AEs were (overall %, % EVE-related) stomatitis (52.8%; 50.8%) and asthenia (22.8%; 14.6%). The most frequently reported hematologic AE were (overall %, % EVE-related) anemia (14.4%; 8.1%) and thrombocytopenia (5.9%; 4.6%). AE-related treatment discontinuations were higher in elderly ((3)70 years) versus non-elderly patients (23.8% vs. 13.0%). The incidence of EVE-related AEs in both elderly and non-elderly patients appeared to be lower in first-line ABC versus later lines. The incidence of AEs (including stomatitis/pneumonitis) was independent of BMI status (post-hoc analysis). Overall, 8.5% of patients experienced at least one EVE-related SAE. Of the 121 on-treatment deaths (5.7%), 66 (3.1%) deaths were due to disease progression and 46 (2.2%) due to AEs; 4 deaths were suspected to be EVE-related. CONCLUSIONS: This is the largest ever reported safety dataset on a general patient population presenting ABC treated with EVE plus EXE and included a sizeable elderly subset. Although the patients were more heavily pretreated, the safety profile of EVE plus EXE in BALLET was consistent with BOLERO-2. CLINICAL TRIAL REGISTRATION: EudraCT Number: 2012-000073-23. [less ▲]

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See detailIntegrating roots into a whole plant network of flowering time genes in Arabidopsis thaliana
Bouché, Frédéric ULg; D'Aloia, Maria; Tocquin, Pierre ULg et al

in Scientific Reports (2016), 6

Molecular data concerning the involvement of roots in the genetic pathways regulating floral transition are lacking. In this study, we performed global analyses of the root transcriptome in Arabidopsis in ... [more ▼]

Molecular data concerning the involvement of roots in the genetic pathways regulating floral transition are lacking. In this study, we performed global analyses of the root transcriptome in Arabidopsis in order to identify flowering time genes that are expressed in the roots and genes that are differentially expressed in the roots during the induction of flowering. Data mining of public microarray experiments uncovered that about 200 genes whose mutations are reported to alter flowering time are expressed in the roots (i.e. were detected in more than 50% of the microarrays). However, only a few flowering integrator genes passed the analysis cutoff. Comparison of root transcriptome in short days and during synchronized induction of flowering by a single 22-h long day revealed that 595 genes were differentially expressed. Enrichment analyses of differentially expressed genes in root tissues, gene ontology categories, and cis-regulatory elements converged towards sugar signaling. We concluded that roots are integrated in systemic signaling, whereby carbon supply coordinates growth at the whole plant level during the induction of flowering. This coordination could involve the root circadian clock and cytokinin biosynthesis as a feed forward loop towards the shoot. [less ▲]

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See detailControlled synthesis of poly(vinylamine)-based copolymers by organometallic-mediated radical polymerization
Dréan, Mathilde ULg; Guégan, Philippe; Detrembleur, Christophe ULg et al

in Macromolecules (2016), 49(13), 4817-4827

iving/controlled polymerization methods have enabled the synthesis of numerous (co)polymers with defined compositions and architectures. However, the precision design of poly(vinylamine)-based copolymers ... [more ▼]

iving/controlled polymerization methods have enabled the synthesis of numerous (co)polymers with defined compositions and architectures. However, the precision design of poly(vinylamine)-based copolymers remains challenging despite their extensive use in various fields of applications and the clear benefits to finely tune their properties. Here, we report on a two-step strategy for the synthesis of tailor-made poly(vinylamine) derivatives through the organometallic- mediated radical (co)polymerization (OMRP) of N-vinyl- acetamide and/or N-methylvinylacetamide followed by acid hydrolysis of the acetamide groups. A series of well-defined homopolymers as well as statistical and block copolymers with pendant primary and/or secondary amines having controlled molar masses, compositions, and low dispersities were produced accordingly. The reactivity ratios of the comonomers as well as the composition drift along the chain were determined in order to have a precise idea of the polymer structures. These advances represent a significant step toward an efficient platform for synthesis of this important class of amino group-containing (co)polymers. [less ▲]

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