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See detailMyelofibrosis patients in Belgium: disease characteristics
Devos, Timothy; Zachée, Pierre; Bron, Domonique et al

in Acta Clinica Belgica (in press)

Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according ... [more ▼]

Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according to predefined disease parameters (diagnosis, risk categories, hemoglobin ,10 g/dl, spleen size, constitutional symptoms, platelet count, myeloblast count), with a view to obtaining a deeper understanding of the proportion of patients that may benefit from the novel myelofibrosis therapeutic strategies. Methods: A survey was used to collect data on prevalence and disease parameters on all myelofibrosis patients seen at each of 18 participating hematologic centers in 2011. Aggregated data from all centers were used for analysis. Analyses were descriptive and quantitative. Results: A total of 250 patients with myelofibrosis were captured; of these, 136 (54%) were male and 153 (61%) were over 65 years old. One hundred sixty-five (66%) of myelofibrosis patients had primary myelofibrosis and 85 (34%) had secondary myelofibrosis. One hundred ninety-three myelofibrosis patients (77%) had a palpable spleen. About a third of patients (34%) suffered from constitutional symptoms. Two hundred twenty-two (89%) myelofibrosis patients had platelet count§50 000/ml and 201 (80%) had platelet count §100 000/ml. Of 250 patients, 85 (34%) had a myeloblast count §1%. Six (2%) patients had undergone a splenectomy. Thirteen (5.2%) patients had undergone radiotherapy for splenomegaly. Conclusions: The results of this survey provide insight into the characteristics of the Belgian myelofibrosis population. They also suggest that a large proportion of these patients could stand to benefit from the therapies currently under development. [less ▲]

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See detailSomatotrope GHRH/GH/IGF-1 axis at the crossroad between immunosenescence and elder frailty
Bodart, Gwennaëlle ULg; Goffinet, Lindsay; Morrhaye, Gabriel et al

in Annals of the New York Academy of Sciences (in press)

Immunosenescence as complex modifications of immunity with age could be related to the so-called frailty syndrome of elderly leading to an inadequate response to minimal aggression. Functional decline ... [more ▼]

Immunosenescence as complex modifications of immunity with age could be related to the so-called frailty syndrome of elderly leading to an inadequate response to minimal aggression. Functional decline, the loss of ability to perform activities of daily living, is related to the decrease in physiological reserves and frailty and is a frequent outcome of hospitalization in older patients. Links between immunosenescence and frailty were explored and 20 immunological parameters were affected in seniors with functional decline. IGF-1, thymopoeisis and telomere length were part of these markers. A strong relationship between insulin-like growth factor-1 (IGF-1) and thymic ouput was evidenced. IGF-1, mediator of GH, was subsequently shown to induce IL-7 secretion in cultured primary human thymic epithelial cells (TECs). We are also exploring the ‘stress hypothesis’ according which an acute stress is the discriminator revealing a frailty susceptility. GH can counteract the deleterious immunosuppressive effect of stress-induced steroids. Under non-stressing conditions, the immunosenescent system preserves physiological responses, while in stressing conditions, the combination of immunosenescence and a defect in somatotrope axis might lead to functional decline. [less ▲]

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See detailSpecial issue on the political impact(s) of metaphors: Introduction
Perrez, Julien ULg; Reuchamps, Min

in Metaphor and the Social World (in press)

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See detailProjections photographiques et cinéma des premiers temps : La houillère de Gustave Marissiaux et les origines du cinéma minier
Mélon, Marc-Emmanuel ULg

in Intermédialités : Histoire et Théorie des Arts, des Lettres et des Techniques = Intermediality: History and Theory of the Arts, Literature and Technologies (in press)

Les spectacles de projection conçus par Gustave Marissiaux entre 1903 et 1926, en particulier le vaste documentaire intitulé "La houillère" (1905) est ici inscrit dans une histoire sociale des images ... [more ▼]

Les spectacles de projection conçus par Gustave Marissiaux entre 1903 et 1926, en particulier le vaste documentaire intitulé "La houillère" (1905) est ici inscrit dans une histoire sociale des images projetées et mis en rapport avec le cinéma minier des premiers temps [less ▲]

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See detailCharacterization of Cichopeptins, New Phytotoxic Cyclic Lipodepsipeptides Produced by Pseudomonas cichorii SF1-54, and Their Role in Bacterial Midrib Rot Disease of Lettuce
Huang, CJ; Pauwelyn, E.; Ongena, Marc ULg et al

in Molecular Plant-Microbe Interactions [=MPMI] (in press)

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See detailTien Shan geohazards database: Earthquakes and landslides
Havenith, Hans-Balder ULg; Strom, Alexander; Torgoev, Isakbek et al

in Geomorphology (in press)

In this paper we present new and review already existing landslide and earthquake data for a large part of the Tien Shan, Central Asia. For the same area, only partial databases for sub-regions have been ... [more ▼]

In this paper we present new and review already existing landslide and earthquake data for a large part of the Tien Shan, Central Asia. For the same area, only partial databases for sub-regions have been presented previously. They were compiled and new data were added to fill the gaps between the databases. Major new inputs are products of the Central Asia Seismic Risk Initiative (CASRI): a tentative digital map of active faults (even with indication of characteristic or possible maximum magnitude) and the earthquake catalogue of Central Asia until 2009 that was now updated with USGS data (to May 2014). The new compiled landslide inventory contains existing records of 1600 previously mapped mass movements and more than 1800 new landslide data. Considering presently available seismo-tectonic and landslide data, a target region of 1200 km (E–W) by 600 km (N–S) was defined for the production of more or less continuous geohazards information. This target region includes the entire Kyrgyz Tien Shan, the South-Western Tien Shan in Tajikistan, the Fergana Basin (Kyrgyzstan, Tajikistan and Uzbekistan) as well as the Western part in Uzbekistan, the North-Easternmost part in Kazakhstan and a small part of the Eastern Chinese Tien Shan (for the zones outside Kyrgyzstan and Tajikistan, only limited information was available and compiled)... [less ▲]

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See detailCephalothrix gen. nov. (Cyanobacteria): towards an intraspecific phylogenetic evaluation by multilocus analyses
Malone, Camila da Silva Francieli; Rigonato, Janaina; Laughinghouse, Haywood Dail et al

in International Journal of Systematic and Evolutionary Microbiology (in press)

For more than a decade, the taxonomy of Phormidiaceae has been problematic, since morphologically similar organisms represent phylogenetically distinct entities. Based on 16S rRNA analyses, the ... [more ▼]

For more than a decade, the taxonomy of Phormidiaceae has been problematic, since morphologically similar organisms represent phylogenetically distinct entities. Based on 16S rRNA analyses, the polyphyletic genus Phormidium and other gas-vacuolated oscillatorioids appear scattered throughout the cyanobacterial tree of life. Recently, several studies have focused on understanding the oscillatorioid taxa at the generic level. At the specific level, there are few studies characterizing cyanobacterial strains using combined datasets (morphology, ultrastructure, and molecular multi-locus analyses). Using a multi-facet approach, we propose a new, well-defined genus, Cephalothrix gen. nov., by analyzing seven filamentous strains morphologically 'intermediate' between gas-vacuolated taxa and Phormidium. Furthermore, we characterize two new species: Cephalothrix komarekiana (CCIBt 3277, CCIBt 3279, CCIBt 3523, CCALA 155, SAG 75.79, and UTEX 1580) and Cephalothrix lacustris (CCIBt 3261). The generic name and specific epithets were proposed under the provisions of the International Code of Nomenclature for algae, fungi, and plants. [less ▲]

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See detailLes troubles du sommeil chez l'enfant autiste, quel rôle pour le pédopsychiatre?
Abate Ekollo, Joëlle; Malchair, Alain ULg

in Acta Psychiatrica Belgica (in press)

Les troubles du sommeil sont fréquents chez l’enfant et leurs origines sont diverses. Ces troubles ont leur ancrage dans le développement neurophysiologique et psychoaffectif de l’enfant. Les enfants ... [more ▼]

Les troubles du sommeil sont fréquents chez l’enfant et leurs origines sont diverses. Ces troubles ont leur ancrage dans le développement neurophysiologique et psychoaffectif de l’enfant. Les enfants souffrant de troubles du spectre autistique présentent un déficit de sommeil, qui peut durer jusqu’à l’adolescence. Les troubles du spectre autistique comportent des comorbidités multiples, dont des altérations du sommeil. Ils sont importants à caractériser dans cette population, car ils peuvent avoir un impact négatif sur les comportements diurnes. Par ailleurs, ils entrainent souvent des difficultés au sein de la famille. La prise en charge doit avant tout prendre en compte le contexte environnemental afin d’améliorer les habitudes et l’hygiène du sommeil. Des questionnaires ainsi que des agendas de sommeil ont été remplis par des parents afin de démontrer l’importance d’une évaluation et d’une prise en compte des troubles du sommeil chez les enfants souffrant d’autisme en consultation pédopsychiatrique. [less ▲]

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See detailLes tensions entre langue et politique en Belgique: linguistiques ou communautaires?
Dassargues, Alix ULg; Perrez, Julien ULg; Reuchamps, Min ULg

in Revue Internationale de Politique Comparée (in press)

Since its creation in 1830, Belgium has experienced tensions between language and politics. The question of the linguistic or community-related nature of these tensions should be raised since they have ... [more ▼]

Since its creation in 1830, Belgium has experienced tensions between language and politics. The question of the linguistic or community-related nature of these tensions should be raised since they have regularly been referred to as linguistic by some researchers and as community-related by others. But the choice of these adjectives is not unimportant considering they frame the representations of the political issues at hand. The aim of this article is to tackle this question from the combined perspective of linguistics and political science. In the first, the article explores the genealogy of the adjectives ‘linguistic’ and ‘community-related’ as well as the multiplicity of their uses in the scientific literature. In the second part, it focuses on the ways citizens see and talk about Belgian federalism through the respective analyses of their mental representations and their conceptual metaphors. Such interdisciplinary endeavour, bringing together theoretical and empirical insights, seeks to yield a renewed understanding of the political relations in Belgium and to contribute to the debate about plurilingual societies. [less ▲]

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See detailSaturn’s auroral morphology and field-aligned currents during a solar wind compression
Badman, S.V.; Provan, G.; Bunce, E.J. et al

in Icarus (in press)

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See detailDrivers of the winter–spring phytoplankton bloom in a pristine NW Mediterranean site, the Bay of Calvi (Corsica): A long-term study (1979–2011)
Goffart, Anne ULg; Hecq, Jean-Henri ULg; Legendre, Louis

in Progress in Oceanography (in press)

This work is based on a long time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) between 1979 and 2011, which include physical characteristics ... [more ▼]

This work is based on a long time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) between 1979 and 2011, which include physical characteristics (31 years), chlorophyll a (chl a, 15 years), and inorganic nutrients (13 years). Because samples were collected at relatively high frequencies, which ranged from daily to biweekly during the winter-spring period, it was possible to (1) evidence the key role of two interacting physical variables, i.e. water temperature and wind intensity, on nutrient replenishment and phytoplankton dynamics during the winter-spring period, (2) determine critical values of physical factors that explained interannual variability in the replenishment of surface nutrients and the winter-spring phytoplankton bloom, and (3) identify previously unrecognized characteristics of the planktonic ecosystem. Over the >30 year observation period, the main driver of nutrient replenishment and phytoplankton (chl a) development was the number of wind events (mean daily wind speed >5 m s-1) during the cold-water period (subsurface water ≤13.5°C). According to winter intensity, there were strong differences in both the duration and intensity of nutrient fertilization and phytoplankton blooms (chl a). The trophic character of the Bay of Calvi changed according to years, and ranged from very oligotrophic (i.e. subtropical regime, characterized by low seasonal variability) to mesotrophic (i.e. temperate regime, with a well-marked increase in nutrient concentrations and chl a during the winter-spring period) during mild and moderate winters, respectively. A third regime occurred during severe winters characterized by specific wind conditions (i.e. high frequency of northeasterly winds), when Mediterranean “high nutrient - low chlorophyll” conditions occurred as a result of enhanced cross-shore exchanges and associated offshore export of the nutrient-rich water. There was no long-term trend (e.g. climatic) in either nutrient replenishment or the winter-spring phytoplankton bloom between 1979 and 2011, but both nutrients and chl a reflected interannual and decadal changes in winter intensity. [less ▲]

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See detailEmerging ecosystem services governance issues in the Belgium ecosystem services community of practice
Keune, Hans; Dendoncker, Nicolas; Popa, Florin et al

in Ecosystem Services (in press)

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See detailState Created Barriers to Exit - The Example of the Acquisition of Alstom by General Electric
Petit, Nicolas ULg

in Competition Policy International (in press)

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See detailResidue and microwear analyses of the stone tools from Schöningen
Rots, Veerle ULg; Hardy, Bruce; Serangeli, Jordi et al

in Journal of Human Evolution (in press)

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See detailDevelopment by the sol–gel process of highly dispersed Ni–Cu/SiO2 xerogel catalysts for selective 1,2-dichloroethane hydrodechlorination into ethylene
Pirard, Sophie ULg; Mahy, Julien ULg; Pirard, Jean-Paul ULg et al

in Microporous and Mesoporous Materials (in press)

Ni–Cu/SiO2 xerogel catalysts have been synthesized by cogelation of industrial tetraethoxysilane (Dynasil) and chelates of Ni and Cu with industrial 3-(2-aminoethylamino)propyltrimethoxysilane (Dynasylan ... [more ▼]

Ni–Cu/SiO2 xerogel catalysts have been synthesized by cogelation of industrial tetraethoxysilane (Dynasil) and chelates of Ni and Cu with industrial 3-(2-aminoethylamino)propyltrimethoxysilane (Dynasylan DAMO) in industrial ethanol denatured with diethyl phthalate. Despite the use of industrial grade reagents, highly dispersed bimetallic Ni–Cu/SiO2 xerogel catalysts were obtained. These samples are composed of completely accessible Ni–Cu alloy crystallites with sizes of 1.6–3.4 nm located inside silica particles exhibiting a monodisperse microporous distribution. It appears that the bimetallic complex acts as a nucleation agent in the formation of silica particles. The combination of results obtained from the calculation of the metal ratio in catalysts, H2 chemisorption and transmission electron microscopy allowed calculating the surface composition of the nickel–copper particles in Ni–Cu/SiO2 cogelled xerogel catalysts. Values obtained indicate a very pronounced surface enrichment with copper. While 1,2-dichloroethane hydrodechlorination over pure nickel mainly produces ethane, increasing copper content in bimetallic catalysts results in an increase in ethylene selectivity. The specific consumption rate of 1,2-dichloroethane decreases when copper loading increases. The turnover frequency, that is, the number of catalytic cycle per active site (nickel atom and its surrounding copper atoms) and per second, seems to be independent of surface composition of alloy particles. [less ▲]

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See detailOrder short-term memory capacity predicts nonword reading and spelling in first and second grade
Binamé, Florence ULg; Poncelet, Martine ULg

in Reading and Writing An Interdisciplinary Journal (in press)

Recent theories of short-term memory (STM) distinguish between item information, which reflects the temporary activation of long-term representations stored in the language system, and serial-order ... [more ▼]

Recent theories of short-term memory (STM) distinguish between item information, which reflects the temporary activation of long-term representations stored in the language system, and serial-order information, which is encoded in a specific representational system that is independent of the language network. Some studies examining the relationship between reading acquisition and verbal STM for order and item information separately in beginning readers have found that order STM capacity is independently predictive of nonword decoding abilities in first grade, but item STM is not. In this longitudinal study, we first aimed to explore whether this finding also holds for nonword spelling abilities. We also sought to determine whether order STM capacity remains an independent predictor of nonword decoding and spelling abilities in the second year of reading instruction. For this purpose, 70 typically developing children were followed over 3 years, from kindergarten to second grade. In kindergarten, children were administered order and item STM tasks and phonological awareness tasks, in addition to tasks assessing letter name knowledge, vocabulary knowledge, and nonverbal reasoning. In first and second grades, the children’s word and nonword reading and spelling abilities were assessed. The results revealed that order STM capacity was a robust independent predictor of nonword reading and spelling abilities in first and second grade, but was not related to the abilities to read and spell words. The specific role of order STM in the acquisition of the sublexical reading and spelling routes is discussed. [less ▲]

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See detailIn vitro approach to study the synergistic effects of tobramycin and clarithromycin against Pseudomonas aeruginosa biofilms using prokaryotic or eukaryotic culture media
Thellin, Olivier ULg; Zorzi, Willy ULg; Jolois, Olivier et al

in International Journal of Antimicrobial Agents Corresponding (in press)

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See detailDiversity of germination strategies and dormancy of graminoid and forb species of campo rupestre grasslands
Le Stradic, Soizig ULg; Silveira, Fernando A. O.; Buisson, Elise et al

in Austral Ecology (in press)

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See detailAbelian bordered factors and periodicity
Charlier, Emilie ULg; Harju, Tero; Puzynina, Svetlana et al

in European Journal of Combinatorics (in press)

A finite word u is said to be bordered if u has a proper prefix which is also a suffix of u, and unbordered otherwise. Ehrenfeucht and Silberger proved that an infinite word is purely periodic if and only ... [more ▼]

A finite word u is said to be bordered if u has a proper prefix which is also a suffix of u, and unbordered otherwise. Ehrenfeucht and Silberger proved that an infinite word is purely periodic if and only if it contains only finitely many unbordered factors. We are interested in abelian and weak abelian analogues of this result; namely, we investigate the following question(s): Let w be an infinite word such that all sufficiently long factors are (weakly) abelian bordered; is w (weakly) abelian periodic? In the process we answer a question of Avgustinovich et al. concerning the abelian critical factorization theorem. [less ▲]

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See detailMonitoring the laccase reaction of vanillin and poplar hydrolysate
Sòti, Valentin; Jacquet, Nicolas ULg; Apers, Sandra et al

in Journal of Chemical Technology & Biotechnology (in press)

BACKGROUND: Laccase is an intensively researched enzyme for industrial use. Except for decolorisation measurements, HPLC analysis is the conventional method for monitoring the phenolic removal during ... [more ▼]

BACKGROUND: Laccase is an intensively researched enzyme for industrial use. Except for decolorisation measurements, HPLC analysis is the conventional method for monitoring the phenolic removal during laccase enzyme reaction. This paper reports an investigation of the continuous UV absorbance follow-up of the laccase reaction with steam pretreated poplar hydrolysate. RESULTS: Vanillin was used as a model substrate and lignocellulose xylose rich fraction (XRF) as a biologically complex substrate for laccase detoxification. The reaction was followed by HPLC-UV as well as by UV spectrometric measurements. Results suggest that the reaction can be successfully monitored by measuring the change of UV absorbance at 280 nm, without previous compound separation. In case of XRF experiments the spectrophotometric follow-up is especially useful, as HPLC analysis takes a long time and provides less information than in case of single substrates. The method seems to be suitable for optimization and process control. CONCLUSION: The obtained results can help to construct a fast, easy and straightforward monitoring system for laccase-phenolic substrate reactions. [less ▲]

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See detailDynamiques transactionnelles de reconnaissance et professionnalisation des stagiaires : perspectives pour la formation initiale
Dejean, Karine ULg

in Education et Formation (in press)

Cet article prend appui sur une recherche doctorale. A partir de l’analyse de récits d’expériences marquantes, à forte charge émotionnelle, rapportées par des enseignants débutants, des schémas ... [more ▼]

Cet article prend appui sur une recherche doctorale. A partir de l’analyse de récits d’expériences marquantes, à forte charge émotionnelle, rapportées par des enseignants débutants, des schémas d’intelligibilité de ces situations vécues ont été construits. Ceux-ci rendent compte des transformations identitaires et émotionnelles des enseignants débutants au travers des dynamiques transactionnelles de reconnaissance. Ces résultats ouvrent des perspectives pour la formation initiale des enseignants et l’accompagnement des enseignants débutants. Les schémas d’intelligibilité pourront être utilisés dans une démarche de réflexivité pour faciliter le décodage de situations professionnelles à forte charge émotionnelle vécues par l’enseignant et l’aider à donner sens à ses expériences [less ▲]

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See detailL'espace transitionnel winnicotien et l'_Urraum_ kantien
Seba, Jean-Renaud ULg

in Revista Natureza Humana (in press)

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See detailWhere do hybrids come from? Entrepreneurial team heterogeneity as an avenue for the emergence of hybrid organizations
Dufays, Frédéric ULg; Huybrechts, Benjamin ULg

in International Small Business Journal (in press)

This conceptual paper aims to respond to the poorly addressed question of the emergence of hybrid organizations – i.e. organizations that embrace several institutional logics. It does so by developing a ... [more ▼]

This conceptual paper aims to respond to the poorly addressed question of the emergence of hybrid organizations – i.e. organizations that embrace several institutional logics. It does so by developing a model and a set of propositions focusing on the heterogeneity of the entrepreneurial team as a possible driver for hybridity throughout the entrepreneurial process and up to the emergence of a hybrid organization. As contributions to the literatures on (collective) entrepreneurship, imprinting and hybrid organizations, we advance several avenues and conditions under which the heterogeneity of the entrepreneurial team may imprint the entrepreneurial process and lead to the creation of hybrid organizations. Our propositions connect the individual, team and organizational levels and thus advance our understanding of how institutional logics can be combined across different levels of analysis and throughout the stages of an entrepreneurial process. [less ▲]

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See detailLe Laboratoire d’Analyse statistique des langues anciennes : cinquante années de recherches
Longrée, Dominique ULg

in Etudes Classiques (Namur, Belgium) (in press)

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See detailWhy is later age at retirement beneficial for cognition? Results from a French population-based study
Grotz, Catherine ULg; Meillon, Céline; Amieva, Hélène et al

in Journal of Nutrition, Health & Aging (in press)

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See detailA radio-map of the colliding winds in the very massive binary system HD93129A
Benaglia, Paula; Marcote, Benito; Moldon, Javier et al

in Astronomy and Astrophysics (in press)

Radio observations are an effective tool to discover particle acceleration regions in colliding-wind binaries, through detection of synchrotron radiation; these regions are natural laboratories for the ... [more ▼]

Radio observations are an effective tool to discover particle acceleration regions in colliding-wind binaries, through detection of synchrotron radiation; these regions are natural laboratories for the study of relativistic particles.Wind-collision region (WCR) models can reproduce the radio continuum spectra of massive binaries that contain both thermal and non-thermal radio emission; however, key constraints for models come from high-resolution imaging. Only five WCRs have been resolved to date at radio frequencies at milliarcsec (mas) angular scales. The source HD93129A, prototype of the very few known O2 I stars, is a romising target for study: recently, a second massive, early-type star about 50 mas away was discovered, and a non-thermal radio source detected in the region. Preliminary long-baseline array data suggest that a significant fraction of the radio emission from the system comes from a putative WCR. We sought evidence that HD93129A is a massive binary system with colliding stellar winds that produce non-thermal radiation, through spatially resolved images of the radio emitting regions. Methods.We completed observations with the Australian Long Baseline Array (LBA) to resolve the system at mas angular resolutions and reduced archival Australia Telescope Compact Array (ATCA) data to derive the total radio emission. We also compiled optical astrometric data of the system in a homogeneous way. We reduced historical Hubble Space Telescope data and obtained absolute and relative astrometry with milliarcsec accuracy. The astrometric analysis leads us to conclude that the two stars in HD93129A form a gravitationally bound system. The LBA data reveal an extended arc-shaped non-thermal source between the two stars, indicative of a WCR. The wind momentum-rate ratio of the two stellar winds is estimated. The ATCA data show a point source with a change in flux level between 2003-4 and 2008-9, that is modeled with a non-thermal power-law spectrum with spectral indices of - 1:03 +/- 0:09 and -1:21 +/- 0:03 respectively. The mass-loss rates derived from the deduced thermal radio emission and from the characteristics of the WCR are consistent with estimates derived by other authors. [less ▲]

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See detailImaginer-lire le Capital
Pieron, Julien ULg

in Cahiers d'Etudes Germaniques (in press)

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See detailA serious LAT relationship or a crazy machine? Metaphors in citizens’ perception of Belgian federalism
Perrez, Julien ULg; Reuchamps, Min

in Mots. Les Langages du Politique (in press)

This paper proposes a quantitative and qualitative corpus-based analysis of the use of metaphors in political discourse from the original perspective of citizen discourse. Our data were collected from ... [more ▼]

This paper proposes a quantitative and qualitative corpus-based analysis of the use of metaphors in political discourse from the original perspective of citizen discourse. Our data were collected from focus group discussions respectively held in the French-speaking and Dutch-speaking parts of Belgium, which tackled the citizens’ perceptions of Belgian federalism. Our findings suggest that citizens do produce metaphors when talking about complex political processes and that these metaphors reveal different political visions. This research also suggests differences in saliency of the source domains in terms of which citizens make sense of Belgian federalism. In this regard, the family domain, and more especially the metaphor BELGIAN FEDERALISM IS A LOVE RELATIONSHIP appears to function as an important conceptual reference point for the citizens’ understanding of the political relations in the Belgian context. [less ▲]

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See detailVanadium fine-structure K-shell electron impact ionization cross sections for fast-electron diagnostic in laser-solid experiments
Palmeri, P; Quinet, Pascal ULg; Batani, D

in Atomic Data & Nuclear Data Tables (in press)

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See detailReflexive Loops on Scaling issues in Landscape Quality Assessment
Schmitz, Serge ULg; Vanderheyden, Vincent ULg

in Land Use Policy (in press)

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See detailLes ambiguïtés de l’anthropomorphisme : de la divinité agissante à sa statue dans la céramique grecque
Collard, Hélène ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce ... [more ▼]

L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce, la figuration anthropomorphe des dieux est largement majoritaire. Toutefois, en se tournant vers un support particulier, le vase peint, et un type de représentation particulier, la statue divine, on montrera ici que l’anthropomorphisme a pu amener une certaine ambiguïté. Dans la céramique, les représentations de statues fonctionnent sur plusieurs modes, selon la chronologie. C’est ce que l’on propose d’analyser, en examinant un groupe de vases décorés d’un thème semblable et sur lesquels une divinité est représentée, mais soit sous la forme d’une figure « vivante », soit d’une statue plus ou moins bien caractérisée. Cette étude permettra d’aborder les concepts de « fixité » et de « mouvement » de/dans l’image, mais aussi d’explorer quelques pistes de réflexions sur l’image divine et, plus largement, sur les modes de représentation du divin en Grèce ancienne. [less ▲]

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See detailImbalance between oxygen photoreduction and antioxidant capacities in Symbiodinium cells exposed to combined heat and high light stress
Roberty, Stéphane ULg; Fransolet, David; Cardol, Pierre ULg et al

in Coral Reefs (in press)

During last decades coral reefs have been affected by several large-scale bleaching events and such phenomenon is expected to increase in frequency and severity in the future thus compromising their ... [more ▼]

During last decades coral reefs have been affected by several large-scale bleaching events and such phenomenon is expected to increase in frequency and severity in the future thus compromising their survival. High sea surface temperature accompanied by high levels of solar irradiance has been found to be responsible for the induction of an oxidative stress ultimately ending with the disruption of the symbiosis between cnidarians and Symbiodinium. Since two decades many studies have pointed out the water-water cycle as being one of the primary mediators of this phenomenon, but the impacts of environmental stress on the O2 reduction by PSI and the associated ROS-detoxifying enzymes remain to be determined. In this study, we analyzed the impacts of an acute thermal and light stress on the WWC in the model Symbiodinium strain A1. We observed that high light treatment at 26°C resulted in the up-regulation of superoxide dismutase (SOD), ascorbate peroxidase (APX) and glutathione reductase (GR) activities and an increased production of Reactive Oxygen Species (ROS) with no significant change in O2-dependent electron transport. Under high light and at 33°C, O2-dependent electron transport was significantly increased relative to total electron transport. This increase was concomitant with a two-fold increase in ROS generation compared to the treatment at 26°C, while enzymes involved in the WWC were largely inactivated. These data show for the first time that combined heat and light stress inactivate antioxidant capacities of the WWC, and suggests that its photoprotective functions are overwhelmed under these conditions. This study also indicates that cnidarians may be more prone to bleach if they harbor Symbiodinium cells having a highly active Mehler-type electron transport, unless they are able to quickly up-regulate their antioxidant capacities. [less ▲]

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See detailVIEUX PHENOTYPE ET NOUVEAUX GENOTYPES Actualités dans le domaine des adénomes hypophysaires
GERARD, Caroline ULg; JEDIDI, Haroun ULg; PETROSSIANS, Patrick ULg et al

in Revue Médicale de Liège (in press)

Gigantism and acromegaly, usually caused by a pituitary adenoma linked innapropriate secretion of growth hormon (GH) are generally considered as very rare diseases, even if, regarding some authors, their ... [more ▼]

Gigantism and acromegaly, usually caused by a pituitary adenoma linked innapropriate secretion of growth hormon (GH) are generally considered as very rare diseases, even if, regarding some authors, their cumulative prevalence is about 1/5000. Starting from the historical case of a giant from Liège we will describe the different types of GH pituitary adenomas and their physiopathology. We will overall discuss rare forms of inherited GH secreting pituitary adenomas like the FIPA (familial inherited isolated pituitary adenomas) and the X-LAG (X linked acrogigantism), both described in Liège, respectively in 2000 and 2014. [less ▲]

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See detailNewt life after fish introduction: extirpation of paedomorphosis in a mountain fish lake and newt use of satellite pools
Denoël, Mathieu ULg; Scime, Patrick; Zambelli, Nicola

in Current Zoology (in press), 62

Fish introduction is one of the main causes of amphibian decline worldwide. It affects particularly rare aquatic phenotypes such as paedomorphs, which retain gills during the adult stage. In this context ... [more ▼]

Fish introduction is one of the main causes of amphibian decline worldwide. It affects particularly rare aquatic phenotypes such as paedomorphs, which retain gills during the adult stage. In this context, we determined whether small wetlands, such as pools surrounding fished and fishless lakes, could sustain paedomorphic and metamorphic newts. To this end, we surveyed lakes known historically to sustain Alpine newts (Ichthyosaura alpestris) as well as 35 nearby pools. On the basis of the published records, the only known population exhibiting paedomorphosis in the Swiss Alps was found to be extirpated by salmonid introductions. However, the metamorphs persisted in peripheral pools, paedomorphosis was discovered at a new locality, and overwintering larvae were still present in one of the lakes. These results show the importance of conserving varied aquatic habitats such as pools in mountainous environments where the main resources can become unsuitable for amphibians because of fish introductions. Pools may also function as reservoirs in maintaining newt populations until programs to remove fish from lakes can be carried out. It is not known if paedomorphs could reappear after fish removal. However, the combined resilience of amphibians after fish removal and the genetic basis for paedomorphosis highlighted in other taxa by previous studies suggest that there is the potential to maintain this intraspecific case of diversity even after its disappearance. [less ▲]

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See detailVitamin D status after a high dose of cholecalciferol in healthy and burn subjects
ROUSSEAU, Anne-Françoise ULg; DAMAS, Pierre ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (in press)

Background: Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a ... [more ▼]

Background: Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a cholecalciferol (VD3) bolus on VD status in adult burn patients (Group B, GB) after admission, compared to healthy subjects (Group H, GH). Methods: Both groups received an oral dose of 100,000 IU VD3. Blood samples were collected before (D0) and 7 days (D7) after bolus to measure 250H-D, 1,25(OH)2-D, parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23). Albumin (ALB) and VD binding protein (DBP) were measured and used to calculate free 25OH-D level. Data were expressed as median (min–max) or proportions. Results: A total of 49 subjects were included: 29 in GH and 20 in GB. At D0, prevalence of VD deficiency was higher in GB: 25OH-D was 21.5 (10.1–46.3) ng/ml in GH vs 11 (1.8–31.4) ng/ml in GB. DBP and ALB were lower in GB. At D7, DBP was stable in both groups while ALB decreased in GB. 25OH-D increased by 66.6 (13.5–260.3)% in GH. In GB, changes in 25OH-D extended from 36.7% to 333.3% with a median increase of 33.1%. Similar changes were observed in each group for free 25OH-D. High FGF23 levels were observed in GB. Conclusions: This study highlighted the differences in VD status and in response to a high dose VD3 in burn patients when compared to healthy patients. Pitfalls in VD status assessment are numerous during acute burn care: 25OH-D measurement needs cautious interpretation and interest of free 25OH-D is still questionable. They should not prevent burn patients to receive VD supplements during acute care. Higher doses than general recommendations should probably be considered. [less ▲]

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See detailLa manie et la mélancolie comme crises de l’identité narrative et de l’intentionnalité
Englebert, Jérôme ULg; Stanghellini, Giovanni

in Evolution Psychiatrique (in press)

Objectives: Our objective is to achieve a phenomenological cross-study of melancholic and manic crises. To do this, we analyze the relationship between these two psychopathological states by means of the ... [more ▼]

Objectives: Our objective is to achieve a phenomenological cross-study of melancholic and manic crises. To do this, we analyze the relationship between these two psychopathological states by means of the concepts of "narrative identity" and "intentionality". Method: From clinical cases and with reference to various theoretical models derived from phenomenological psychopathology, we discuss similarities and differences between mania and melancholia. Results: Narrative identity is based on a double movement: that of the enunciation of a speech focused on his history and that of an act of creation. From different clinical situations, we find that: (1) the melancholic retains the ability to elaborate a narrative about his history but the creative dimension of this narrative is absent, and (2) conversely, the manic experiences only the creative dimension. Discussion: Intentionality, as the tendency of consciousness to move toward something beyond itself, proves to be the center of the manic existence without being able to set itself within the boundaries of factual constraints. The melancholic, conversely, experiences an existence in which consciousness has lost its capacity to aim beyond itself. Conclusions: Melancholia and mania are quite specific forms of being-in-world with particular identity and temporal experiences. These two states share a fundamental psychopathological feature, that we named here “manque chiasmatique”: they are disorders of the intentional movement that constitutes narrative identity, that is, of the dialectics between the rootedness (“enracinenment”) of self in its past and the possibility of creation of a new identity. [less ▲]

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See detailSustaining Inter-Organizational Relationships across Institutional Logics and Power Asymmetries: the Case of Fair Trade
Nicholls, Alex; Huybrechts, Benjamin ULg

in Journal of Business Ethics (in press)

In Fair Trade (FT), as well as in other ‘mixed-form’ fields (Becchetti & Huybrechts 2008; Marwell & McInerney 2005), non-profit organizations and social enterprises have been partnering with large ... [more ▼]

In Fair Trade (FT), as well as in other ‘mixed-form’ fields (Becchetti & Huybrechts 2008; Marwell & McInerney 2005), non-profit organizations and social enterprises have been partnering with large corporations over long time periods despite the presence of conditions that might be expected to destabilize such relationships. These conditions include striking differences in size, economic power, and organizational goals or ‘logics’. Given these asymmetries, the collaborations are typically seen as problematic and temporary because the stronger party (the corporation) will impose its (market) logics upon the weaker one (the social enterprise), leading to either instrumentalizing and corrupting the latter or to the breakdown of the collaboration. Whilst some of the literature on FT and other market-oriented social movements has tended to depict corporate participation as a threat to the original goals of the social movement and to the integrity of partnering social enterprises (e.g. Fridell et al. 2008; Reed 2009), there is evidence of a set of social enterprise-corporate relationships that persist over time and cannot be simply summarized as dominated by the sole corporate, market logic. These examples illustrate the emergence of new working relationships across the conventional divides between distinct sectors – the public, private, and civil society – that offer new approaches to managing power asymmetries and apparently conflicting logics – typically, in FT and more generally in social entrepreneurship, market and social justice/welfare logics (Battilana & Lee 2014; Defourny & Nyssens 2006; Huybrechts & Nicholls 2012; Smith et al. forthcoming). This leads to the following research question: Under what conditions can inter-organizational relationships emerge and be sustained despite power asymmetries and the presence of distinct, potentially conflicting, institutional logics? The analysis in this paper aims to extend theory by providing an alternative to more deterministic analyses of inter-organizational relationships that suggest that the more powerful actor will always impose its logics upon the less powerful organization thus undermining the persistence of the relationship over time. In the process, this research adds a new construct to existing theory around the resolution of conflict in institutional logics by suggesting that dynamic persistence is also evident in contrast to examples of conflict resolution through dominance, compromise, hybridization, synthesis, or relationship breakdown. Based on the analysis of the relationships between commercial buyers and FTOs, initially embodying market and social justice logics respectively, this paper proposes a set of key conditions under which dynamic persistence can be observed even in the presence of power asymmetries. [less ▲]

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See detailHuman Papillomavirus-related tumours of the oropharynx display a lower tumour hypoxia signature
Hanns, Elodie; Job, Sylvie; Coliat, Pierre et al

in Oral Oncology (in press)

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See detailEfficient standard error formulas of ability estimators with dichotomous item response models
Magis, David ULg

in Psychometrika (in press)

This paper focuses on the computation of asymptotic standard errors (ASE) of ability estimators with dichotomous item response models. A general framework is considered and ability estimators are defined ... [more ▼]

This paper focuses on the computation of asymptotic standard errors (ASE) of ability estimators with dichotomous item response models. A general framework is considered and ability estimators are defined from a very restricted set of assumptions and formulas. This approach encompasses most standard methods such as maximum likelihood, weighted likelihood, maximum a posteriori and robust estimators. A general formula for the ASE is derived from the theory of M-estimation. Well-known results are found back as particular cases for the maximum and robust estimators, while new ASE proposals for the weighted likelihood and maximum a posteriori estimators are presented. These new formulas are compared to traditional ones by means of a simulation study under Rasch modeling. [less ▲]

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See detailThe importance of the tumor microenvironment in the therapeutic management of cancer
Pottier, Charles ULg; Wheatherspoon, Alodie; RONCARATI, Patrick ULg et al

in Expert Review of Anticancer Therapy (in press)

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See detailPreoperative Adherence to Continuous Positive Airway Pressure among Obstructive Sleep Apnea Patients
Deflandre; Degey, S; BONHOMME, Vincent ULg et al

in Minerva Anestesiologica (in press)

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See detailLa flexicurité revisitée : analyse qualitative interdisciplinaire du discours de travailleurs à l'aide d'un logiciel collaboratif »
Beuker, Laura ULg; DE CIA, Julie ULg; Dervaux, Amélie ULg et al

in Recherches Qualitatives (in press)

L’ambition de cet article est double : explorer les vertus de l’utilisation d’un logiciel d’analyse qualitative dans le cadre d’un travail interdisciplinaire sur la flexicurité, et réaliser une revue de ... [more ▼]

L’ambition de cet article est double : explorer les vertus de l’utilisation d’un logiciel d’analyse qualitative dans le cadre d’un travail interdisciplinaire sur la flexicurité, et réaliser une revue de littérature transversale à partir des problématiques concrètes que ce concept cristallise dans le vécu des travailleurs. La flexicurité constitue un oxymore qui prône la recherche d’un équilibre entre besoins de flexibilité et de sécurité sur le marché du travail. Cet équilibre est avant tout un objectif politique, mais il reste fragile aux yeux des acteurs concernés. En cherchant à croiser le regard analytique de trois disciplines – psychologie, gestion et sociologie –, nous avons recouru au logiciel Cassandre (Lejeune, 2008) pour dégager des tensions discursives autour des notions de flexibilité et de sécurité dans un corpus de vingt entretiens qualitatifs. L’article permet ainsi de concrétiser l’intérêt et les limites de l’utilisation d’un logiciel d’analyse qualitative dans le cadre d’un travail interdisciplinaire. [less ▲]

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See detailPregnancy-associated glycoprotein (PAG) concentration in plasma and milk samples for early pregnancy diagnosis in Lacaune dairy sheep
El Amiri, Bouchra; Melo de Sousa, Noelita ULg; Alvarez-Oxiley, Andrea et al

in Research in Veterinary Science (in press)

In the present study, four RIA systems (RIA-1 to -4) based on two antisera raised against ovine pregnancyassociated glycoproteins (ovPAGs), combined with an ovine or a bovine PAG tracer were used to ... [more ▼]

In the present study, four RIA systems (RIA-1 to -4) based on two antisera raised against ovine pregnancyassociated glycoproteins (ovPAGs), combined with an ovine or a bovine PAG tracer were used to measure PAG concentrations in plasma and milk samples of dairy ewes. Blood and milk samples were collected on different days of gestation: 0, 18, 20, 22, 25, 28, 32, 42, and 49. From day 20 onward, the PAG in plasma could be detected in all pregnant ewes using the four RIA systems. By using milk, except for RIA-1, the other systems showed a sensitivity of 100% from day 28 of gestation onward. In plasma, PAG concentrations were higher in multiple than in single pregnancies, while no clear relationship was observed in milk. In conclusion, milk is a good alternative to plasma for early pregnancy diagnosis in sheep from day 28 to day 42. [less ▲]

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See detailEvidence of contrasting patterns for suppression and reappraisal emotional regulation strategies in alexithymia.
Laloyaux, Julien ULg; Fantini, Carole; Lemaire, Morgan ULg et al

in Journal of Nervous & Mental Disease (in press)

Alexithymia generally refers to difficulties in identifying and describing emotions. In this paper, two studies explored whether the emotional deficits observed in alexithymia may be related to the use of ... [more ▼]

Alexithymia generally refers to difficulties in identifying and describing emotions. In this paper, two studies explored whether the emotional deficits observed in alexithymia may be related to the use of emotional regulation strategies. Relations with various socio-demographic variables were also explored. In the first study, 255 students completed the Emotion Regulation Questionnaire (ERQ) and the Toronto Alexithymia Scale-20. For the second study, 1107 participants from the general population completed the ERQ and the Bermond-Vorst Alexithymia Questionnaire. Results demonstrated that alexithymia was related to the use of a suppression strategy and in particular to difficulties verbalizing emotions, suggesting that the capacity to communicate and name one’s emotion is a central aspect in alexithymia. Concerning socio-demographic variables, alexithymia and the use of a suppression strategy were found to be related to age and to be higher in males. The results of these studies and their clinical implications for treatment are discussed. [less ▲]

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See detailGenetic determinants of Crohn’s disease and ulcerative colitis phenotypes in 34,819 patients.
Cleynen, Isabelle; Boucher, Gabrielle; Jostins, Luke et al

in Lancet (in press)

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See detailHalomethyl-cobalt(bis-acetylacetonate) for the controlled synthesis of functional polymers
Demarteau, Jérémy ULg; Kermagoret, Anthony; German, Ian et al

in Chemical Communications (in press)

Novel organocobalt complexes featuring weak C–CoL2 bonds (L = acetylacetonate) are prepared and used as sources of halomethyl radicals. They permit the precision synthesis of a-halide functionalized and ... [more ▼]

Novel organocobalt complexes featuring weak C–CoL2 bonds (L = acetylacetonate) are prepared and used as sources of halomethyl radicals. They permit the precision synthesis of a-halide functionalized and telechelic polymers in organic media or in water. Substitution of halide by azide allows derivatization of polymers using the CuAAC click reaction. [less ▲]

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See detailUsing seismic inversions to obtain an indicator of internal mixing processes in main-sequence solar-like stars
Buldgen, Gaël ULg; Dupret, Marc-Antoine ULg; Reese, Daniel Roy

in Astronomy and Astrophysics (in press)

Context. Currently, seismic modelling is one of the best ways of building accurate stellar models, thereby providing accurate ages. However, current methods are affected by simplifying assumptions ... [more ▼]

Context. Currently, seismic modelling is one of the best ways of building accurate stellar models, thereby providing accurate ages. However, current methods are affected by simplifying assumptions concerning stellar mixing processes. In this context, providing new structural indicators that are less model-dependent and more sensitive to mixing processes is crucial. Aims. We wish to build a new indicator for core conditions (i.e. mixing processes and evolutionary stage) on the main sequence. This indicator tu should be more sensitive to structural differences and applicable to older stars than the indicator t presented in a previous paper. We also wish to analyse the importance of the number and type of modes for the inversion, as well as the impact of various constraints and levels of accuracy in the forward modelling process that is used to obtain reference models for the inversion. Methods. First, we present a method of obtaining new structural kernels in the context of asteroseismology. We then use these new kernels to build a new indicator of central conditions in stars, denoted tu, and test it for various effects including atomic diffusion, various initial helium abundances, and various metallicities, following the seismic inversion method presented in our previous paper. We then study the indicator’s accuracy for seven different pulsation spectra including those of 16CygA and 16CygB and analyse how it depends on the reference model by using different constraints and levels of accuracy for its selection Results. We observe that the inversion of the new indicator tu using the SOLA method provides a good diagnostic for additional mixing processes in central regions of stars. Its sensitivity allows us to test for diffusive processes and chemical composition mismatch. We also observe that using modes of degree 3 can improve the accuracy of the results, as well as using modes of low radial [less ▲]

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See detailQuantify ing cereal - reaping microwear on flint tools: an experimental approach
Linton, Jimmy ULg; Monna, Fabrice; Martineau, Rémi et al

in Archaeometry (in press)

From the earliest Neolithic in the Near East to the last Chalcolithic cultures in Western Europe, certain flint tools have been used as sickles to harvest cereals. Such harvesting tools can be identified ... [more ▼]

From the earliest Neolithic in the Near East to the last Chalcolithic cultures in Western Europe, certain flint tools have been used as sickles to harvest cereals. Such harvesting tools can be identified through use-wear analyses, because cutting herbaceous plants produces specific wear-traces on the working edge of flint blades. The aim of this work is to explore harvesting-driven microwear variability and, more particularly, intensity of use as a governing factor. To achieve this objective, an experiment was designed consisting in the production of flint replicas to be used as harvesting tools, in various controlled conditions. A simple, cost-effective method of quantifying wear-traces by meas uring polish extent is developed, requiring only classical use-wear observation equipment. Polish extent shows monotonic correlation with the amount of work, expressed either in terms of time or as the quantity of cereals harvested. Polish extent measurement is therefore proposed as a reliable and powerful descriptor of use intensity. [less ▲]

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See detailPrevalence of auditory verbal hallucinations in a general population: A group comparison study
Kråkvik; Laroi, Frank ULg; Kalhovde, Anne Martha et al

in Scandinavian Journal of Psychology (in press)

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See detailMyoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer
Fahmy, Karim ULg; Gonzalez, Arnaud; Arafa, Mohammad et al

in International Journal of Cancer = Journal International du Cancer (in press)

Pancreatic ductal adenocarcinoma is one of the most deadly forms of cancers with no satisfactory treatment to date. Recent studies have identified myoferlin, a ferlin family member, in human pancreas ... [more ▼]

Pancreatic ductal adenocarcinoma is one of the most deadly forms of cancers with no satisfactory treatment to date. Recent studies have identified myoferlin, a ferlin family member, in human pancreas adenocarcinoma where its expression was associated to a bad prognosis. However, the function of myoferlin in pancreas adenocarcinoma has not been reported. In other cell types, myoferlin is involved in several key plasma membrane processes such as fusion, repair, endocytosis and tyrosine kinase receptor activity. In this study, we showed that myoferlin silencing in BxPC-3 human pancreatic cancer cells resulted in the inhibition of cell proliferation in vitro and in a significant reduction of the tumor volume in chick chorioallantoic membrane assay. In addition to be smaller, the tumors formed by the myoferlin-silenced cells showed a marked absence of functional blood vessels. We further demonstrated that this effect was due, at least in part, to an inhibition of VEGFA secretion by BxPC-3 myoferlin-silenced cells. Using immunofluorescence and electron microscopy, we linked the decreased VEGFA secretion to an impairment of VEGFA exocytosis. The clinical relevance of our results was further strengthened by a significant correlation between myoferlin expression in a series of human pancreatic malignant lesions and their angiogenic status evaluated by the determination of the blood vessel density. [less ▲]

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See detailXenobiotic and Immune-Relevant Molecular Biomarkers in Harbor Seals as Proxies for Pollutant Burden and Effects?
Lehnert, Kristina; Ronnenberg, Katrin; Weijs, Liesbeth et al

in Archives of Environmental Contamination & Toxicology (in press)

Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. Persistent organic pollutants (POPs) and trace elements are hazardous contaminants which ... [more ▼]

Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. Persistent organic pollutants (POPs) and trace elements are hazardous contaminants which accumulate in tissues of harbor seals. POPs and trace elements can negatively affect the immune-system and have been reported e.g. to increase susceptibility to viral infections in seals. Biomarkers of the xenobiotic metabolism, cytokines and heat-shock-protein as cell mediators of the immune-system were established to evaluate the impact of environmental stressors on harbor seals. Harbor seals (n=54) were captured on sandbanks in the North Sea during 2009 to 2012. Medicals including hematology were performed, RNAlater blood samples were taken and analyzed using quantitative Polymerase Chain Reaction. Normalized transcript copy numbers were correlated to hematology and POP concentration in blood, and trace metals in blood and fur. [less ▲]

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See detailCharacterization of the placoderm (Gnathostomata) assemblage from the tetrapod-bearing locality of Strud (Belgium, Upper Famennian)
Olive, Sébastien ULg; Clément, Gaël; Daeschler, Edward et al

in Palaeontology (in press)

The placoderm fauna of the late Famennian tetrapod-bearing locality of Strud, Belgium, is studied on the basis of historical and newly collected material. It includes the previously described antiarch ... [more ▼]

The placoderm fauna of the late Famennian tetrapod-bearing locality of Strud, Belgium, is studied on the basis of historical and newly collected material. It includes the previously described antiarch Grossilepis rikiki, the groenlandaspidid Turrisaspis strudensis sp. nov. and the actinolepidoideid Phyllolepis undulata. P. undulata is thoroughly described and joins the list of the valid Phyllolepis species confidently diagnosed. A morphometrical analysis performed on the centronuchal and anterior ventrolateral plates of the Phyllolepis material demonstrates that there is only one species of Phyllolepis in Belgium (thus, Phyllolepis konincki becomes a junior synonym of P. undulata), that P. rossimontina (Pennsylvania) is a synonym of P. undulata and that the unity of the genus Phyllolepis is strongly supported, although the characterization of several species within this genus is blurred. The strong resemblance between the faunal compositions in Strud and Red Hill (Pennsylvania, USA) suggests important faunal exchanges between these regions of the Euramerica landmass. [less ▲]

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See detailDiscrimination of deciduous tree species from time series of unmanned aerial system imagery
Lisein, Jonathan ULg; Michez, Adrien ULg; Claessens, Hugues ULg et al

in PLoS ONE (in press)

Technology advances can revolutionize Precision Forestry by providing accurate and fine forest information at tree level. This paper addresses the question of how and particularly when Unmanned Aerial ... [more ▼]

Technology advances can revolutionize Precision Forestry by providing accurate and fine forest information at tree level. This paper addresses the question of how and particularly when Unmanned Aerial System (UAS) should be used in order to efficiently discriminate deciduous tree species. A time series of high resolution UAS imagery was collected to cover the growing season from leaf flush to leaf fall. Full benefit was taken of the temporal resolution of UAS acquisition, one of the most promising features of small drones. The disparity in forest tree phenology is at the maximum during early spring and late autumn. But the phenology state that optimized the classification result is the one that minimizes the spectral variation within tree species groups and, at the same time, maximizes the phenologic differences between species. Sunlit tree crowns (5 deciduous species groups) were classified using a Random Forest approach for monotemporal, two-date and three-date combinations. The end of leaf flushing was the most efficient single-date time window. Multitemporal datasets definitely improve the overall classification accuracy. But single-date high resolution orthophotomosaics, acquired on optimal time-windows, result in a very good classification accuracy (overall out of bag error of 16%). [less ▲]

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See detailExperimental and computational micro–mechanical investigations of compressive properties of polypropylene/multi–walled carbon nanotubes nanocomposite foams
Wan, Fangyi; Tran, Minh Phuong; Leblanc, Christophe ULg et al

in Mechanics of Materials (in press)

The compressive behavior of nanocomposite foams is studied by both experimental and computational micro-mechanics approaches with the aim of providing an efficient computational model for this kind of ... [more ▼]

The compressive behavior of nanocomposite foams is studied by both experimental and computational micro-mechanics approaches with the aim of providing an efficient computational model for this kind of material. The nanocomposites based on polypropylene (PP) and different contents of multi-walled carbon nanotubes (CNTs) are prepared by melt mixing method. The nanocomposite samples are foamed using super-critical carbon dioxide (ScCO2) as blowing agent at different soaking temperatures. The influence of this foaming parameter on the morphological characteristics of the foam micro-structure is discussed. Differential Scanning Calorimetry (DSC) measurements are used to quantify the crystallinity degree of both nanocomposites and foams showing that the crystallinity degree is reduced after the foaming process. This modification leads to mechanical properties of the foam cell walls that are different from the raw nanocomposite PP/CNTs material. Three--point bending tests are performed on the latter to measure the flexural modulus in terms of the crystallinity degree. Uniaxial compression tests are then performed on the foamed samples under quasi-static conditions in order to extract the macro-scale compressive response. Next, a two-level multi-scale approach is developed to model the behavior of the foamed nanocomposite material. On the one hand, the micro-mechanical properties of nanocomposite PP/CNTs cell walls are evaluated from a theoretical homogenization model accounting for the micro-structure of the semi-crystalline PP, for the degree of crystallinity, and for the CNT volume fraction. The applicability of this theoretical model is demonstrated via the comparison with experimental data from the described experimental measurements and from literature. On the other hand, the macroscopic behavior of the foamed material is evaluated using a computational micro-mechanics model using tetrakaidecahedron unit cells and periodic boundary conditions to estimate the homogenized properties. The unit cell is combined with several geometrical imperfections in order to capture the elastic collapse of the foamed material. The numerical results are compared to the experimental measurements and it is shown that the proposed unit cell computational micro-mechanics model can be used to estimate the homogenized behavior, including the linear and plateau regimes, of nanocomposite foams. [less ▲]

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See detailMeasurement of circulating 25-hydroxyvitamin D: A historical review
Delvin, Edgar; LE GOFF, Caroline ULg; CAVALIER, Etienne ULg et al

in Practical Laboratory Medicine (in press)

The constantly increasing requests for the measurement of serum 25-hydroxyvitamin D over the last years has led reagent manufacturers to market different automated and semi-automated methods, that being ... [more ▼]

The constantly increasing requests for the measurement of serum 25-hydroxyvitamin D over the last years has led reagent manufacturers to market different automated and semi-automated methods, that being unfortunately not fully harmonized, yield different results. Liquid chromatography coupled to tandem mass spectrometry (LC/MS2) has more recently been introduced. This approach allows the distinction between the two forms of 25-hydroxyvitamin D and to measure other metabolites. This approach also requires harmonization to curtail the differences between the different analytical methods. To meet this requirement, the American National Institutes of Health (NIH), the CDC (Centre for Disease Control and Prevention) in Atlanta, the NIST (National Institute of Standards and Technology) and the vitamin D Reference laboratory of Ghent University have pooled their expertise to develop a standardization program. This article reviews the main elements and the difficulties of the automated and semi-automated methods for 25-hydroxyvitamin D, from sample preparation to the analytical phase, as well as those related to mass spectrometry. It also addresses the issues related to the clinical decision thresholds and the possibility of measurements in different biological liquids. [less ▲]

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See detailSpecialist plant species harbour higher reproductive performances in recently restored calcareous grasslands than in reference habitats
Harzé, Mélanie ULg; Mahy, Grégory ULg; Bizoux, Jean-Philippe ULg et al

in Plant Ecology and Evolution (in press)

Background and aims_Calcareous grasslands are local biodiversity hotspots in temperate regions that suffered intensive fragmentation. Ecological restoration projects took place all over Europe. Their ... [more ▼]

Background and aims_Calcareous grasslands are local biodiversity hotspots in temperate regions that suffered intensive fragmentation. Ecological restoration projects took place all over Europe. Their success has traditionally been assessed using a plant community approach. However, population ecology can also be useful to assess restoration success and to understand underlying mechanisms. Methods_We took advantage of three calcareous grassland sites in Southern Belgium, where reference parcels coexist with parcels restored in the late twentieth century and with more recently restored parcels. We evaluated the colonization stage of three specialist species (Sanguisorba minor, Potentilla neumanniana and Hippocrepis comosa) using occurrence data. We also measured the reproductive traits of 120 individuals per species and compared components of fitness between recent restorations, old restorations and reference habitats. Key results_We found that the occurrence of H. comosa was similar in the different restoration classes, whereas both P. neumanniana and S. minor occurrences decreased from reference grasslands to recent restorations. In contrast, these two latter species exhibited a much higher reproductive output in recent restorations, thanks to an increased production of flowers and seeds. Conclusions_Our results suggest that, during colonization of recently restored calcareous grasslands, favourable environmental conditions, low competition and sufficient genetic mixing may lead to an increased fitness of individuals and a faster population growth than in the reference habitat. These results demonstrate how population processes can increase ecological resilience and highlight the interest of a population-based approach to assess the success of ecological restoration. [less ▲]

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See detailCT SCAN FEATURES OF PRESUMPTIVE HAEMORRHAGIC STROKE IN A DOG WITH CUSHING’S DISEASE
Liotta, Annalisa Pia ULg; Cavrenne, Romain; Peeters, Dominique ULg et al

in Case reports in Veterinary Medicine (in press)

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See detailUsing kernels and ecological niche modelling to delineate conservation areas in an endangered patch-breeding phenotype
Denoël, Mathieu ULg; Ficetola, Francesco

in Ecological Applications (in press)

Efficient delineation of conservation areas is a great challenge in maintaining biodiversity. Kernel density estimators (KDEs) are a powerful tool in this perspective, but they have not been applied at ... [more ▼]

Efficient delineation of conservation areas is a great challenge in maintaining biodiversity. Kernel density estimators (KDEs) are a powerful tool in this perspective, but they have not been applied at the population level on patch-distributed organisms. This would be particularly worthy for species that need broad habitats beyond those where they can be sampled; such as terrestrial lands for pond-breeding amphibians. The aim of this study was to compare different approaches for the identification of suitable areas for conservation: KDE, ecological niche modelling, and a combination of KDE and niche models. Paedomorphosis was chosen as a model system because this is an important form of intraspecific variation that is present in numerous taxa, but geographically localized within species and globally endangered. 277 ponds were sampled in one of the hotspots of paedomorphosis to determine the abundance and distribution of paedomorphs (i.e. individuals retaining gills at the adult stage) of the palmate newt (Lissotriton helveticus), with emphasis on the connections between the most valuable populations. KDEs gave insights into the surface areas required to balance the maintenance of certain number of connected ponds and the respective number of disjoint areas in which the whole population is divided. The inclusion of barriers in the models helped in accurately designing the limits of the areas to protect. Alone, habitat models were not able to successfully delineate the area to protect, but the integration between terrestrial suitable areas or barriers and KDE allowed an objective identification of areas required for conservation. Overall, the best performance was observed by the KDE integrating ecological barriers, and by the combination between KDE and niche modelling. In a broader perspective, KDEs are thus a pertinent tool in providing quantitative spatial measurements to delineate conservation areas based on patch-abundance data with a specific focus to connectivity. [less ▲]

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See detailEffect of wheel traffic on the physical properties of a Luvisol
Destain, Marie-France ULg; Roisin, Christian; Dalcq, Anne-Catherine ULg et al

in Geoderma (in press)

The effects of machine traffic were assessed on a Luvisol in a temperate climate area in Belgium. Soil samples were taken from topsoil (0.07-0.25 m) and subsoil (0.35-0.50 m), on plots under long-term ... [more ▼]

The effects of machine traffic were assessed on a Luvisol in a temperate climate area in Belgium. Soil samples were taken from topsoil (0.07-0.25 m) and subsoil (0.35-0.50 m), on plots under long-term reduced tillage (RT) and conventional tillage (CT). Cone index (CI), bulk density (BD) and precompression stress (Pc) were chosen as indicators of mechanical strength. Mercury intrusion porosimetry was used to characterize the soil microporosity structure. It was presented in two forms: (i) cumulative pore volume vs. equivalent pore radius r, from which four classes of porosity were defined: r < 0.2 μm, 0.2 ≤ r < 9 µm, 9 ≤ r < 73 µm and r ≥ 73 μm; (ii) pore-size distribution (PSDs). In the reference situation where there had been no recent passage of machines, the voids with 0.2 ≤ r < 9 µm were the most important class in RT topsoil. The voids with r ≥ 73 µm represented the main porosity class in the topsoil of CT. In the subsoil, for both tillage systems, the porosity was almost equally distributed between voids with 0.2 ≤ r < 9 µm and voids with r greater than 9 µm. Machine traffic was carried out when the soil water content was close to the optimum Proctor. Although unfavourable, these wet conditions often occur during the beet harvesting period in Belgium. The highest modifications in soil structure (increase in BD and Pc, reduction of macroporosity r ≥ 73 μm) were observed in the topsoil of CT. More limited modifications were noticed in the soil structure of RT topsoil and subsoil layers but these latter are problematic in that the soil would no longer be loosened by subsequent tillage. These modifications could lead to soil consolidation as a result of wheel traffic year after year. [less ▲]

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See detailSteel hollow columns with an internal profile filled with self-compacting concrete under fire conditions
Chu, Thi Binh; Gernay, Thomas ULg; Dotreppe, Jean-Claude ULg et al

in Proceeding of the Romanian Academy. Series A, Mathematics, Physics, Technical Sciences, Information Science (in press)

A detailed experimental and numerical investigation has been performed on the behavior under fire conditions of concrete filled steel hollow section (CFSHS) columns. In this study the internal ... [more ▼]

A detailed experimental and numerical investigation has been performed on the behavior under fire conditions of concrete filled steel hollow section (CFSHS) columns. In this study the internal reinforcement consists of another profile (tube or H section) being embedded with the concrete, and filling is realized by self-compacting concrete (SCC). Ten columns filled with self-compacting concrete embedding another steel profile have been tested in the Fire Testing Laboratory of the University of Liege, Belgium. Numerical simulations on the thermal and structural behavior of these elements have been made using the non linear finite element software SAFIR developed at the University of Liege. There is a rather good agreement between numerical and experimental results, which can be slightly improved by using the ETC (Explicit Transient Creep) model incorporated in SAFIR. This shows that numerical analyses can predict well the behavior of CFSHS columns under fire conditions. The properties at high temperatures of self-compacting concrete are considered the same as those of ordinary concrete. [less ▲]

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See detailEnvironmental impacts of phosphoric acid production using di-hemihydrate process: a Belgian case study
Belboom, Sandra ULg; Szöcs, Carl; Léonard, Angélique ULg

in Journal of Cleaner Production (in press)

This paper undertakes an environmental evaluation of phosphoric acid production, using industrial data from Prayon SA in Belgium. Phosphoric acid is produced using the wet di-hemihydrate process also ... [more ▼]

This paper undertakes an environmental evaluation of phosphoric acid production, using industrial data from Prayon SA in Belgium. Phosphoric acid is produced using the wet di-hemihydrate process also called Central Prayon process. Both grades of phosphoric acid are evaluated: fertilizer and purified grades. Specificities of this plant are highlighted and improvements of the process in terms of energy and facilities integration through years are quantified as environmental benefits. The implementation on site of two sulphuric acid production facilities and their energetic integration allow a reduction of climate change impact of 80%. Results also show the importance of phosphogypsum valorisation which is sold for the main part in this case study. Concerning the purified grade, this specific process has been compared to the thermal process, using Best Available Techniques (BAT) values for the modelling. It shows a reduced environmental impact for the wet process in the majority of categories studies. [less ▲]

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See detailMass-spectrometry-based method for screening of new peptide ligands for G-protein-coupled receptors
Cologna Takeno, Camila; Gilles, Nicolas; Echterbille, Julien ULg et al

in Analytical and Bioanalytical Chemistry (in press)

G-protein-coupled receptors (GPCRs) constitute the largest family of transmembrane proteins. Although implicated in almost all physiological processes in the human body, most of them remain unexploited ... [more ▼]

G-protein-coupled receptors (GPCRs) constitute the largest family of transmembrane proteins. Although implicated in almost all physiological processes in the human body, most of them remain unexploited, mostly because of the lack of specific ligands. The objective of this work is to develop a new mass-spectrometry-based technique capable of identifying new peptide ligands for GPCRs. The strategy is based on the incubation of cellular membranes overexpressing GPCRs with a mixture of peptides that contains potential ligands. Peptide ligands bind to the receptors, whereas other peptides remain in the binding buffer. Bound peptides are eluted from membranes and directly detected, identified, and characterized by MALDI TOF–TOF. The results reveal the efficacy of the procedure for selecting a specific ligand of GPCRs in both simple and complex mixtures of peptides. This new approach may offer direct purification, identification, and characterization of the new ligand in a single workflow. The proposed method is labeling-free and, unlike radio-binding and other techniques, it does not require a previously known labeled ligand of the studied GPCR. All these properties greatly reduce the experimental constraints. Moreover, because it is not based on the principle of a competitive specific binding, this technique constitutes a new tool to discover new ligands not only for known GPCRs, but also for orphan GPCRs [less ▲]

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See detailThe Perceived Value of Passive Animal Health Surveillance: The Case of Highly Pathogenic Avian Influenza in Vietnam
Delabouglise, Alexis; Antoine-Moussiaux, Nicolas ULg; Phan, T.D et al

in Zoonoses and Public Health (in press)

Economic evaluations are critical for the assessment of the efficiency and sustain- ability of animal health surveillance systems and the improvement of their effi- ciency. Methods identifying and ... [more ▼]

Economic evaluations are critical for the assessment of the efficiency and sustain- ability of animal health surveillance systems and the improvement of their effi- ciency. Methods identifying and quantifying costs and benefits incurred by public and private actors of passive surveillance systems (i.e. actors of veterinary author- ities and private actors who may report clinical signs) are needed. This study pre- sents the evaluation of perceived costs and benefits of highly pathogenic avian influenza (HPAI) passive surveillance in Vietnam. Surveys based on participatory epidemiology methods were conducted in three provinces in Vietnam to collect data on costs and benefits resulting from the reporting of HPAI suspicions to vet- erinary authorities. A quantitative tool based on stated preference methods and participatory techniques was developed and applied to assess the non-monetary costs and benefits. The study showed that poultry farmers are facing several options regarding the management of HPAI suspicions, besides reporting the fol- lowing: treatment, sale or destruction of animals. The option of reporting was associated with uncertain outcome and transaction costs. Besides, actors antici- pated the release of health information to cause a drop of markets prices. This cost was relevant at all levels, including farmers, veterinary authorities and private actors of the upstream sector (feed, chicks and medicine supply). One benefit associated with passive surveillance was the intervention of public services to clean farms and the environment to limit the disease spread. Private actors of the poultry sector valued information on HPAI suspicions (perceived as a non-mon- etary benefit) which was mainly obtained from other private actors and media. [less ▲]

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See detailTrunk muscle profile in elite tennis players with and without low back pain
GROSDENT, Stéphanie ULg; Demoulin, Christophe ULg; Souchet, Matthieu et al

in Journal of Sports Medicine & Physical Fitness (in press)

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See detailHigh resolution characterization of the soil organic carbon depth profile in a soil landscape affected by erosion
Jague, Emilien; Sommer, Michael; Saby, Nicolas et al

in Soil & Tillage Research (in press)

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See detailAre neural crest stem cells the missing link between hematopoietic and neurogenic niches?
Coste, Cécile ULg; Neirinckx, Virginie ULg; Gothot, André ULg et al

in Frontiers in Cellular Neuroscience (in press)

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See detailA mysterious giant ichthyosaur from the lowermost Jurassic of Wales
Martin, Jeremy E; Vincent, Peggy; Suan, Guillaume et al

in Acta Palaeontologica Polonica (in press)

Ichthyosaurs rapidly diversified and colonised a wide range of ecological niches during the Early and Middle Triassic period, but experienced a major decline in diversity near the end of the Triassic ... [more ▼]

Ichthyosaurs rapidly diversified and colonised a wide range of ecological niches during the Early and Middle Triassic period, but experienced a major decline in diversity near the end of the Triassic. Timing and causes of this demise and the subsequent rapid radiation of the diverse, but less disparate, parvipelvian ichthyosaurs are still unknown, notably because of inadequate sampling in strata of latest Triassic age. Here, we describe an exceptionally large radius from Lower Jurassic deposits at Penarth near Cardiff, South Wales (UK) the morphology of which places it within the giant Triassic shastasaurids. A tentative total body size estimate, based on a regression analysis of various complete ichthyosaur skeletons, yields a value of 12-15 m. The specimen is substantially younger than any previously reported last known occurrences of shastasaurids and implies a Lazarus range in the lowermost Jurassic for this ichthyosaur morphotype. [less ▲]

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See detailRôle et langue de Tchantchès dans les représentations en castelets des romans de chevalerie : le cas des Quatre fils Aymon
Baiwir, Esther ULg; Impe, Anaëlle

in Enquêtes du Musée de la Vie Wallonne (in press)

Pourquoi et dans quelle mesure les montreurs de marionnettes liégeoises font-ils intervenir Tchantchès aux côtés des grands chevaliers médiévaux, dont les aventures constituent une part importante du ... [more ▼]

Pourquoi et dans quelle mesure les montreurs de marionnettes liégeoises font-ils intervenir Tchantchès aux côtés des grands chevaliers médiévaux, dont les aventures constituent une part importante du répertoire liégeois ? Quels sont ses moyens d'action, mais également ses modes d'expression ? Divers registres de langue apparaissent au fil des spectacles ; quels sont ceux prêtés à notre héros ? Et surtout, ce rôle et cette langue ont-ils évolué au fil du temps ? C’est à ces quelques questions que nous tentons de répondre, en observant les différentes interventions de Tchantchès dans les réécritures des aventures des quatre fils Aymon, l’une des œuvres les plus anciennes et les plus fréquemment jouées dans les théâtres liégeois dévolus aux comédiens de bois. [less ▲]

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See detailThe “Tuchlein” Colours in the Strasbourg Family Text: Recipes for Anthocyanin Pigments
Neven, Sylvie ULg; Sanyova, Jana

in Dyes in History and Archaeology (in press)

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See detailWhen women support the patriarchal family. The dynamics of marriage in a Gécamines mining camp (Katanga province, DR Congo)
Rubbers, Benjamin ULg

in Journal of Historical Sociology (in press)

Based on ethnographic research among the ex-Gécamines workers of Panda (Likasi, DR Congo), this article studies the dynamics of the spousal relationship in a post-industrial context that has been long ... [more ▼]

Based on ethnographic research among the ex-Gécamines workers of Panda (Likasi, DR Congo), this article studies the dynamics of the spousal relationship in a post-industrial context that has been long characterized by paternalism. The results of this research suggest that, though men and women living in this mining community talk about their spousal relationships by invoking the ideal of Christian marriage promoted during the colonial period, in practice such relationships faced important changes following Congolese independence in 1960. The nationalization and subsequent dramatic decline of Gécamines caused changes which directly affected three central dimensions of the colonial family model, namely monogamy, the ideal of domesticity, and male authority. If men and women continue to reference this model, it is because, in times of growing poverty, it allows spouses to remind one other of their respective duties as docile housewives and responsible husbands, and to command respect as virtuous Christian families in the local community. [less ▲]

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See detailAudiometric results after stapedotomy operations in patients with otosclerosis and preoperative small air-bone gaps
SALMON, Caroline ULg; BARRIAT, Sébastien ULg; DEMANEZ, Laurent CH P ULg et al

in Audiology & Neuro-otology (in press)

Objectives: The efficacy of stapedotomies performed on patients with small air-bone gaps (<25 dB, sABG) was compared to the efficacy of the operation in patients who had otosclerosis with high air-bone ... [more ▼]

Objectives: The efficacy of stapedotomies performed on patients with small air-bone gaps (<25 dB, sABG) was compared to the efficacy of the operation in patients who had otosclerosis with high air-bone gaps (≥25 dB, hABG). Methods: This retrospective study evaluates the short-term postoperative air and bone conduction thresholds and air-bone gaps after 181 CO2 laser stapedotomies. Results: A significantly smaller air-bone gap (ABG) and lower air conduction thresholds after surgery were observed in the group of patients who underwent surgery with preoperative ABGs of less than 25 dB. Bone conduction thresholds improve in sABG group after surgery. Conclusions: The results after stapedotomies are good even if the preoperative air-bone gap is small and that the overall risk of hearing deterioration due to stapes surgery remains low. [less ▲]

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See detailAn Exact Method for Designing Shewhart X ̅ and S2 Control Charts to Guarantee the In-Control Performance
Faraz, Alireza ULg; Heuchenne, Cédric ULg

in Journal of Quality Technology (2016)

The in-control performance of the Shewhart X ̅ and S2 control charts with estimated in-control parameters has been evaluated by a number of authors. Results indicate an unrealistically large amount of ... [more ▼]

The in-control performance of the Shewhart X ̅ and S2 control charts with estimated in-control parameters has been evaluated by a number of authors. Results indicate an unrealistically large amount of Phase I data is needed to have the desired in-control average run length (ARL) value in Phase II. To overcome this problem, it has been recommended that the control limits be adjusted based on a bootstrap method to guarantee that the in-control ARL is at least a specified value with a certain specified probability. In our paper we present simple formulas for the required control limits so that practitioners do not have to use the bootstrap method. An assumption of normality is required. The advantage of our proposed method is in its simplicity; there is no bootstrapping and the control chart constants do not depend on the Phase I sample data. [less ▲]

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See detailMapping of riparian invasive species with supervised classification of Unmanned Aerial System (UAS) imagery
Michez, Adrien ULg; Piégay, Hervé; Lisein, Jonathan ULg et al

in International Journal of Applied Earth Observation and Geoinformation (2016), 44

Riparian zones are key landscape features, representing the interface between terrestrial and aquatic ecosystems. Although they have been influenced by human activities for centuries, their degradation ... [more ▼]

Riparian zones are key landscape features, representing the interface between terrestrial and aquatic ecosystems. Although they have been influenced by human activities for centuries, their degradation has increased during the 20th century. Concomitant with (or as consequences of) these disturbances, the invasion of exotic species has increased throughout the world’s riparian zones. In our study, we propose a easily reproducible methodological framework to map three riparian invasive taxa using Unmanned Aerial Systems (UAS) imagery: Impatiens glandulifera Royle, Heracleum mantegazzianum Sommier and Levier, and Japanese knotweed (Fallopia sachalinensis (F. Schmidt Petrop.), Fallopia japonica (Houtt.) and hybrids). Based on visible and near-infrared UAS orthophoto, we derived simple spectral and texture image metrics computed at various scales of image segmentation (10,30, 45, 60 using eCognition software). Supervised classification based on the random forests algorithm was used to identify the most relevant variable (or combination of variables) derived from UAS imagery for mapping riparian invasive plant species. The models were built using 20% of the dataset, the rest of the dataset being used as a test set (80%). Except for H. mantegazzianum, the best results in terms of global accuracy were achieved with the finest scale of analysis (segmentation scale parameter = 10). The best values of overall accuracies reached 72%, 68%, and 97% for I. glandulifera, Japanese knotweed, and H. mantegazzianum respectively. In terms of selected metrics, simple spectral metrics (layer mean / camera brightness) were the most used. Our results also confirm the added value of texture metrics (GLCM derivatives) for mapping riparian invasive species. The results obtained for I. glandulifera and Japanese knotweed do not reach sufficient accuracies for operational applications. However, the results achieved for H. mantegazzianum are encouraging. The high accuracies values combined to relatively light model-inputs needed (delineation of a few umbels) make our approach a serious contender as a cost-effective tool to improve the field management of H. mantegazzianum. [less ▲]

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See detailReassessment of the acrylamide risk: Belgium as a case-study
Claes, Wendie; De Meulenaer, Bruno; Huyghebaert, André et al

in Food Control (2016), 59

Acrylamide is a food process contaminant with carcinogenic and genotoxic properties. As a result of intensive research, numerous mitigation initiatives to prevent its formation were suggested and various ... [more ▼]

Acrylamide is a food process contaminant with carcinogenic and genotoxic properties. As a result of intensive research, numerous mitigation initiatives to prevent its formation were suggested and various of them were implemented in the food chain. To evaluate if the mitigation strategies applied were significant, a comparison was made between two time periods (2002e2007 versus 2008e2013) in terms of acrylamide food levels and dietary exposure in Belgian. The most important changes observed are a significant decrease of the acrylamide content in potato crisps and gingerbread, and a significant increase in (instant) coffee. Additionally, the acrylamide content of breakfast cereals, bread and rolls, chocolate and baby biscuits showed a downward trend, whereas for coffee substitute and ready-to-eat French fries (mainly obtained from catering facilities), an upward, although not significant, trend was observed. These changes resulted in only a slight, but insignificant decline of the overall dietary exposure of adults, adolescents and children. The mean and P95 intake estimated in the 2008e2013 period for these consumer groups corresponded to margins of exposure (MOE) ranging between 515 and 236 and between 155 and 71, respectively, when based on the endpoint for neoplastic effects (BMDL10 ¼ 0.17 mg/kg bw per day). Such low MOE values indicate that acrylamide remains an issue for public concern, requiring renewed attention. [less ▲]

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See detailProvenance of Ichthyosaura alpestris (Caudata: Salamandridae) introductions to France and New Zealand assessed by mitochondrial DNA analysis
Arntzen, Jan W.; King, Tania M.; Denoël, Mathieu ULg et al

in The Herpetological Journal (2016), 26

The last century has seen an unparalleled movement of species around the planet as a direct result of human activity, which has been a major contributor to the biodiversity crisis. Amphibians represent a ... [more ▼]

The last century has seen an unparalleled movement of species around the planet as a direct result of human activity, which has been a major contributor to the biodiversity crisis. Amphibians represent a particularly vulnerable group, exacerbated by the devastating effects of chytrid fungi. We report the malicious translocation and establishment of the alpine newt (Ichthyosaura alpestris) to its virtual antipode in North Island of New Zealand. We use network analysis of mitochondrial DNA haplotypes to identify the original source population as I. a. apuana from Tuscany, Italy. Additionally, a population in southern France, presumed to be introduced, is identified as I. a. alpestris from western Europe. However, the presence of two differentiated haplotypes suggests a mixed origin. This type of analysis is made possible by the recent availability of a phylogenetic analysis of the species throughout its natural range. We discuss the particulars of both introductions. [less ▲]

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See detail« La Théorie critique n’a aucun rapport avec la société. » Kluge, Adorno et l’indomptable Leni Peickert
Hamers, Jérémy ULg; Cormann, Grégory ULg

in Tijdschrift voor Filosofie (2016)

In Artists Under the Big Top: Perplexed (1968), Alexander Kluge’s second feature film, as well as in its short sequel The Indomitable Leni Peickert (1969), the filmmaker reflects about the possibility to ... [more ▼]

In Artists Under the Big Top: Perplexed (1968), Alexander Kluge’s second feature film, as well as in its short sequel The Indomitable Leni Peickert (1969), the filmmaker reflects about the possibility to create a « reformed circus » which aims at reintroducing some sensuality in the spectator’s experience. Taking this project as well as its central figure, the apparently passive elephant, as a metaphorical starting point, this article reconstitutes a virtual dialogue between the filmmaker and his friend and former master Theodor W. Adorno around the issue of communicability and effectiveness of Critical Theory. Crossing several text fragments by the philosopher (Dialectic of Enlightenment, Resignation and Education After Auschwitz a.o.) with film excerpts, short stories and interviews by Kluge, this dialogue made of real exchanges, as well as direct and indirect quotes of Adorno in Kluge’s films – considered here to be belated joint projects –, finally tries to give an answer to following crucial question: how can Adorno’s critical reflection remain politically, that is socially effective. [less ▲]

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See detailLarge predatory marine reptiles from the Albian–Cenomanian of Annopol, Poland
Bardet, Nathalie; Fischer, Valentin ULg; Machalski, Marcin

in Geological Magazine (2016)

During the Early–Late Cretaceous transition, marine ecosystems in Eurasia hosted a diverse set of large predatory reptiles that occupied various niches. However, most of our current knowledge of these ... [more ▼]

During the Early–Late Cretaceous transition, marine ecosystems in Eurasia hosted a diverse set of large predatory reptiles that occupied various niches. However, most of our current knowledge of these animals is restricted to a small number of bonebed-like deposits. Little is known of the geographical and temporal extent of such associations. The middle Albian – middle Cenomanian phosphorite-bearing succession exposed at Annopol, Poland produces numerous ichthyosaurian and plesiosaurian fossils. These are mostly isolated skeletal elements (e.g. teeth, vertebrae), but disarticulated partial skeletons and an articulated, sub vertically embedded ichthyosaur skull are also available. The following taxa are identified: ‘Platypterygius’ sp., cf. Ophthalmosaurinae, Ichthyosauria indet., Polyptychodon interruptus, Pliosauridae indet., Elasmosauridae<indet. and Plesiosauria indet. The large-sized ichthyosaur ‘Platypterygius’ and the pliosaurid Polyptychodon interruptus predominate within the upper Albian – middle Cenomanian deposits. The Annopol record, combined with data from England, France and western Russia, suggests that ‘Platypterygius’ and Polyptychodon interruptus formed a long-term, stable ecological sympatry in marine ecosystems of the European archipelago, at least during the Albian – middle Cenomanian. In addition, the marine reptile assemblage from Annopol is distinct from other Eurasian ecosystems in containing also elasmosaurids in its Albian portion. [less ▲]

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See detailBrentano, la théorie des catégories et la définition de la substance
Boccaccini, Federico ULg

in Etudes Philosophiques (2016)

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See detailDevelopment and validation of a short Italian UPPS-P Impulsive Behavior Scale
D'Orta, Isabella; Burnay, Jonathan ULg; Aiello, Daniela et al

in Addictive Behaviors Reports (2015), 2

Impulsivity is a multidimensional construct that plays a prominent role in the development, maintenance, and relapse of addictive disorders. The UPPS-P model of impulsivity, which distinguishes between ... [more ▼]

Impulsivity is a multidimensional construct that plays a prominent role in the development, maintenance, and relapse of addictive disorders. The UPPS-P model of impulsivity, which distinguishes between five impulsivity components (positive urgency, negative urgency, lack of perseverance, lack of premeditation, sensation seeking), has been increasingly investigated during the last decade in relation to addictive and risky behaviors. Unfortunately, it currently lacks a validated scale that allows Italian researchers and clinicians to measure impulsivity based on the UPPS-P model. The current study fills this gap by testing the psychometric properties of a short 20-item Italian scale used to assess the five dimensions of the UPPS-P model in 188 volunteer participants from the community. Confirmatory factor analysis supported a model of five distinct, but interrelated, impulsivity components. The results indicated good internal consistency (Cronbach's α ranges from .73 to .84). Construct validity was evidenced by specific relations with measures of addictive behaviors and depressive symptoms. On the whole, this study demonstrated that the Italian short UPPS-P has good psychometric properties. [less ▲]

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See detailBroadening, Deepening, and Governing Innovation: Flemish Technology Assessment in Historical and Socio-Political Perspective
Van Oudheusden, Michiel ULg; Charlier, Nathan ULg; Rosskamp, Benedikt ULg et al

in Research Policy (2015), 44(10), 1877-1886

This article examines how science, technology, and innovation (STI) policies in Flanders (Belgium) are affected by, and potentially transformed through, technology assessments (TAs). Broadly defined, TAs ... [more ▼]

This article examines how science, technology, and innovation (STI) policies in Flanders (Belgium) are affected by, and potentially transformed through, technology assessments (TAs). Broadly defined, TAs encompass activities and programs that expand and deepen the knowledge base of contemporary knowledge-based economies (KBEs), typically by including new actors (e.g. trade unions), ideas (e.g. science in society), and rationales (e.g. participatory techniques) in STI processes. Starting from the regionalization of STI policy in Belgium and the convergence of Flemish STI around global KBE principles, the article exemplifies how since the 1980s successive Flemish TA waves (early- warning, bottom-up, and interactive TA) have co-evolved with successive generations of Flemish innovation policy. Building on these findings, it argues that Flemish TA has assumed the role of mediator between science and society, both by counteracting and accommodating dominant STI paradigms. By providing a historical and socio-political perspective on TA and innovation policy, the article draws critical attention to the institutional settings and societal contexts in which TA is embedded, and questions TA's strategic utility within contemporary KBEs. This perspective sheds light on the Flemish government's recent decision to close its parliamentary TA institute and the institutional expansion of TA elsewhere in Europe. [less ▲]

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See detailGender differences in responses in Gammarus pulex exposed to BDE-47: a gel-free proteomic approach
Gismondi, Eric ULg; Mazzucchelli, Gabriel ULg; De Pauw, Edwin ULg et al

in Ecotoxicology & Environmental Safety (2015), 122

Very few ecotoxicological studies have considered differences in toxic effects on male and female organisms. Here, we investigated protein expression differences in caeca of Gammarus pulex males and ... [more ▼]

Very few ecotoxicological studies have considered differences in toxic effects on male and female organisms. Here, we investigated protein expression differences in caeca of Gammarus pulex males and females under control conditions (unexposed) and after 96 h exposure to BDE-47. Using gel-free proteomic analysis, we have identified 45 proteins, of which 25 were significantly differently expressed according to sex and/or BDE-47 exposure. These proteins were involved in several biological processes such as energy metabolism, chaperone proteins, or transcription/translation. In unexposed amphipods, 11 proteins were significantly over-expressed in females, and 6 proteins were over-expressed in males. Under BDE-47 stress, 7 proteins were differently impacted according to sex. For example, catalase was over-expressed in exposed females and under-expressed in exposed males, as compared to respective controls. Conversely, proteins involved in energy metabolism were up-regulated in males and down-regulated in females. Our proteomic study showed differences in responses of males and females to BDE-47 exposure, emphasizing that sex is a confounding factor in ecotoxicological assessment. However, due to the limited information existing in databases on Gammarids, it was difficult to define a BDE-47 mechanism of action. The gel-free proteomic seems to be a promising method to develop in future ecotoxicological studies and thus, to improve our understanding of the mechanism of action of xenobiotics. [less ▲]

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See detailA probabilistic model for predicting the uncertainties of the humid stiction phenomenon on hard materials
Hoang Truong, Vinh ULg; Wu, Ling ULg; Paquay, Stéphane et al

in Journal of Computational & Applied Mathematics (2015), 289

Stiction is a major failure in microelectromechanical system (MEMS) devices in which two contacting surfaces can remain stuck together because of the adhesive forces. Due to the difference between the ... [more ▼]

Stiction is a major failure in microelectromechanical system (MEMS) devices in which two contacting surfaces can remain stuck together because of the adhesive forces. Due to the difference between the surfaces roughness and the adhesive force range, the real contact areas are usually smaller than the apparent one, resulting in a scatter in the adhesive forces. Consequently, the stiction is an uncertain phenomenon. In this work, we develop a probabilistic model to predict the uncertainties of stiction due to the capillary forces acting on stiff materials. This model contains two levels: at the deterministic level, the model can predict the pull-out adhesive contact forces for a given surface topology; at the probabilistic level, the model generates independent identically distributed surfaces on which the deterministic solution can be applied to evaluate the uncertainties related to the stiction phenomenon. [less ▲]

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See detailPressure-impulse diagram of a beam developing non-linear membrane action under blast loading
Hamra, Lotfi ULg; Demonceau, Jean-François ULg; Denoël, Vincent ULg

in International Journal of Impact Engineering (2015), 86

The p–I diagram of a frame beam subjected to blast loading is established, including the elastic lateral restraint and inertia offered by the rest of the structure, the development of nonlinear membrane ... [more ▼]

The p–I diagram of a frame beam subjected to blast loading is established, including the elastic lateral restraint and inertia offered by the rest of the structure, the development of nonlinear membrane action and also, the bending-tension (M−N) interaction that develops in the plastic hinges. The analytical procedures to compute the asymptotes in the p–I diagram as well as a parametric study on the p–I diagram are provided. A dimensional analysis of the problem reveals that, under the considered assumptions, four dimensionless parameters mainly influence the required ductility of the beam. Two of them are related to the behavior of the indirectly affected part (the lateral restraint and mass). Another one is related to the mechanical properties of the investigated beam (i.e. the ratio of the bending to axial resistance). The last parameter incorporates scales of the geometry and of the deformed configuration at the onset of the plastic mechanism. [less ▲]

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See detailDo single, double or triple fungicide sprays differentially affect the grain quality in winter wheat?
El Jarroudi, Moussa ULg; kOUADIO, Louis; Junk et al

in Field Crops Research (2015), 183(257-266),

Foliar fungicides in wheat are typically used to safeguard against economic losses from diseases. In this study, we assessed the effects of three fungicide spray regimes [single, double, and triple ... [more ▼]

Foliar fungicides in wheat are typically used to safeguard against economic losses from diseases. In this study, we assessed the effects of three fungicide spray regimes [single, double, and triple treatments] on four different grain quality parameters [thousand grain weight (TGW), test weight (TW), grain protein content (GPC), and Zeleny sedimentation volume (ZSV)] during the 2006–2009 period at two sites in Luxembourg. The fungicides used were generally a mix of chlorothalonil and triazoles. At Burmerange, (cultivar Cubus), the values of TGW, TW, GPC and ZSV ranged from 38 to 62 g, 67 to 83 kg hl−1, 12.0% to 14.7% dry matter (DM), and 27 to 54 ml, respectively. Whereas, at Everlange (cultivar Achat), the ranges of TGW, TW, GPC and ZSV were 42 to 65 g, 65 to 81 kg hl−1, 11.0% to 15.0% DM, and 21 to 66 ml, respectively. In more than 75% cases, the results indicate that fungicides did not significantly affect TW or ZSV at either sites (P > 0.05). However, there was a significant and positive fungicide effect on GPC in 2006 and 2009 at Burmerange, and only in 2006 at Everlange (P < 0.05). On the contrary, TGW was significantly affected at Burmerange in all years, except 2008 when a positive increase was observed compared to control plots; and in 2006 and 2007 at Everlange. Interestingly, when there was an effect of fungicides on a quality parameter, there was no difference among different fungicide treatments. Thus under conditions prevailing in Luxembourg, a single fungicide treatment applied with judicious timing generally resulted in statistically similar grain quality parameters when compared with a double or triple fungicide treatment. [less ▲]

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See detailLe pouvoir des sentiments : Kluge, Adorno, Ferenczi
Hamers, Jérémy ULg; Cormann, Grégory ULg

in Cahiers d'Etudes Germaniques (2015)

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See detailA Parallel Processing Approach to Dynamic Simulations of Combined Transmission and Distribution Systems
Aristidou, Petros ULg; Van Cutsem, Thierry ULg

in International Journal of Electrical Power & Energy Systems (2015), 72

Simulating a power system with both transmission and distribution networks modeled in detail is a huge computational challenge. In this paper, a Schur-complement-based domain decomposition algorithm is ... [more ▼]

Simulating a power system with both transmission and distribution networks modeled in detail is a huge computational challenge. In this paper, a Schur-complement-based domain decomposition algorithm is proposed to provide accurate, detailed dynamic simulations of such systems. The simulation procedure is accelerated with the use of parallel programming techniques, taking advantage of the parallelization opportunities inherent to domain decomposition algorithms. The proposed algorithm is general, portable and scalable on inexpensive, shared-memory, multi-core machines. A large-scale test system is used for its performance evaluation. [less ▲]

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See detailThe harmonic balance method for bifurcation analysis of large-scale nonlinear mechanical systems
Detroux, Thibaut ULg; Renson, Ludovic ULg; Masset, Luc ULg et al

in Computer Methods in Applied Mechanics and Engineering (2015), 296

The harmonic balance (HB) method is widely used in the literature for analyzing the periodic solutions of nonlinear mechanical systems. The objective of this paper is to exploit the method for bifurcation ... [more ▼]

The harmonic balance (HB) method is widely used in the literature for analyzing the periodic solutions of nonlinear mechanical systems. The objective of this paper is to exploit the method for bifurcation analysis, i.e., for the detection and tracking of bifurcations of nonlinear systems. To this end, an algorithm that combines the computation of the Floquet exponents with bordering techniques is developed. A new procedure for the tracking of Neimark–Sacker bifurcations that exploits the properties of eigenvalue derivatives is also proposed. The HB method is demonstrated using numerical experiments of a spacecraft structure that possesses a nonlinear vibration isolation device. [less ▲]

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See detailDerivation and Application of Sensitivities to Assess Transient Voltage Sags caused by Rotor Swings
Weckesser, Tilman; Johannsson, Hjortur; Ostergaard, Jacob et al

in International Journal of Electrical Power & Energy Systems (2015), 72

The paper introduces an approach to investigate voltage sags, which are caused by large generator rotor swings following a transient disturbance. Therefore, the method exploits sensitivities derived from ... [more ▼]

The paper introduces an approach to investigate voltage sags, which are caused by large generator rotor swings following a transient disturbance. Therefore, the method exploits sensitivities derived from the algebraic network equations. These provide information on the impact of a generator on the voltage magnitude at a load bus and the e ffect of load variation on the generator's power injection. It is shown that these sensitivities give valuable information to identify critical generator-load pairs and locations for applying preventive control measures. [less ▲]

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