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[more ▼]Allogeneic stem cell transplantation (allo-SCT) following a non-myeloablative (NMA) or reduced-intensity conditioning (RIC) is considered a valid approach to treat patients with refractory/relapsed Hodgkin lymphoma (HL). When an HLA-matched donor is lacking a graft from a familial haploidentical (HAPLO) donor, a mismatched unrelated donor (MMUD) or cord blood (CB) might be considered. In this retrospective study, we compared the outcome of patients with HL undergoing a RIC or NMA allo-SCT from HAPLO, MMUD or CB. Ninety-eight patients were included. Median follow-up was 31 months for the whole cohort. All patients in the HAPLO group (N = 34) received a T-cell replete allo-SCT after a NMA (FLU-CY-TBI, N = 31, 91%) or a RIC (N = 3, 9%) followed by post-transplant cyclophosphamide. After adjustment for significant covariates, MMUD and CB were associated with significantly lower GvHD-free relapse-free survival (GRFS; hazard ratio (HR) = 2.02, P = 0.03 and HR = 2.43, P = 0.009, respectively) compared with HAPLO donors. In conclusion, higher GRFS was observed in Hodgkin lymphoma patients receiving a RIC or NMA allo-SCT with posttransplant cyclophosphamide from HAPLO donors. Our findings suggest they should be favoured over MMUD and CB in this setting. [less ▲]Detailed reference viewed: 31 (5 ULg) Decision Algorithms for the Retreatment with Viscosupplementation in Patients Suffering from Knee Osteoarthritis: Recommendations from the EUROpean VIScosupplementation COnsensus Group (EUROVISCO)Raman; Henrotin, Yves ; Chevalier, Xavier et alin Cartilage (in press)Detailed reference viewed: 40 (0 ULg) LaBGen: A method based on motion detection for generating the background of a sceneLaugraud, Benjamin ; Pierard, Sébastien ; Van Droogenbroeck, Marc in Pattern Recognition Letters (in press)Given a video sequence acquired with a fixed camera, the generation of the stationary background of the scene is a challenging problem which aims at computing a reference image for a motionless background ... [more ▼]Given a video sequence acquired with a fixed camera, the generation of the stationary background of the scene is a challenging problem which aims at computing a reference image for a motionless background. For that purpose, we developed our method named LaBGen, which emerged as the best one during the Scene Background Modeling and Initialization (SBMI) workshop organized in 2015, and the IEEE Scene Background Modeling Contest (SBMC) organized in 2016. LaBGen combines a pixel-wise temporal median filter and a patch selection mechanism based on motion detection. To detect motion, a background subtraction algorithm decides, for each frame, which pixels belong to the background. In this paper, we describe the LaBGen method extensively, evaluate it on the SBI 2016 dataset and compare its performance with other background generation methods. We also study its computational complexity, the performance sensitivity with respect to its parameters, and the stability of the predicted background image over time with respect to the chosen background subtraction algorithm. We provide an open source C++ implementation at http://www.telecom.ulg.ac.be/labgen. [less ▲]Detailed reference viewed: 186 (43 ULg) Onderhandelen over vorming van een meerderheid en burgemeester worden in België : Welke invloed heeft de regionale wetgeving ?Grandjean, Geoffrey in Chroniques de Droit Public = Publiekrechtelijke Kronieken (in press)Detailed reference viewed: 19 (1 ULg) Amio Acids in PAediatric Parenteral Nutritionvan Goudoever, J; Carnielli, V; Darmaun, D et alin Clinical Nutrition (in press)Detailed reference viewed: 12 (1 ULg) Can electoral inequalities be legally justified?Bouhon, Frédéric in European Review of Public Law (in press), 2016(Automn), In light of the principle of equality, German, Belgian and British election law contain some legal rules that tend to distribute the faculty to influence the composition of the elected assemblies equally ... [more ▼]In light of the principle of equality, German, Belgian and British election law contain some legal rules that tend to distribute the faculty to influence the composition of the elected assemblies equally among the governed people, and others that tend to distribute it unequally. The inequality caused by the latter group may be to some extent legally justified by concerns for the general interest, but also provides rulers with means that help them to remain in power, which is hardly justifiable from a legal perspective. In these legal systems, parties are expected to gain a significant portion of the people’s support: not only should the parliament (as a whole) and its members (as individuals) represent the governed people, but the parties themselves are expected to be sufficiently representative of the people in order to access the legislative assemblies. Notably, this thesis draws examples from the case law of the European Court of Human Rights, from which relevant decisions are mentioned here. [less ▲]Detailed reference viewed: 20 (2 ULg) Milk-clotting properties of plant rennets and their enzymatic, rheological and sensory role in cheese making: a ReviewBen Amira, Amal; Besbes, Souhail; Attia, Hamadi et alin International Journal of Food Properties (in press)Plant rennets hold an important position amongst various coagulants used in cheese technology. The selection of a suitable plant coagulant is important due to the increasing global demands of cheese ... [more ▼]Plant rennets hold an important position amongst various coagulants used in cheese technology. The selection of a suitable plant coagulant is important due to the increasing global demands of cheese alongside reduced supply of calf rennet. Thus, a literature synthesis is presented to investigate recent achievements on their functional properties and enzymatic role in cheese making. Efforts have also been done to compare certain rheological and sensory properties of final products, arising from some plant and animal based rennets. In fact, some coagulants such as actinidin or dubiumin produce cheeses with sensory qualities similar to those produced by animal rennet. Others, like ginger, cucumisin or hieronymain proteases contribute to develop very different textures and flavors, due to excessive proteolytic activity and production of bitter peptides. For milk-clotting enzymes with high non-specific action, several improvement strategies have been developed to produce cheeses with sensory properties close to those of animal rennet. For example, the mixture of coagulants (cardosins/chymosin), the selection of appropriate milk or its ultrafiltration, as well as the increase of salting time of cheese during ripening could be efficient ways to improve texture and reduce bitterness. Concerning cheeses with high yield loss, the whey could be used for a traditional production of whey cheese. To conclude, the selection of appropriate plant rennet with high MCA/PA ratio and the optimization of all coagulation parameters play a central role in manufacturing cheese with superior rheological and sensory properties. [less ▲]Detailed reference viewed: 36 (5 ULg) Physiological and bio-functional properties of gum arabic: a notable interest for certain human diseasesEloundou Mballa, Pierre; Goffin, Dorothée ; Destain, Jacqueline et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)Detailed reference viewed: 263 (155 ULg) Neomelodica music: pop superstars behind a normative wall. Formal, informal and criminal dimensions of the Neapolitan entertainment industryMazzola, Alessandro in The European Review of Organised Crime (in press), 14(2), Detailed reference viewed: 22 (2 ULg) On the phase behaviour of oxetane-CO2 and propargylic alcohols-CO2 binary mixtures by in situ infrared micro-spectrometryZaky, Mohamed; Boyaval, Amélie ; Grignard, Bruno et alin Journal of Supercritical Fluids (in press)The phase behaviour of carbon dioxide/propargylic alcohols and carbon dioxide/oxetanes mixtures has been investigated using in-situ FTIR microspectrometry that allows us determining the evolution of the ... [more ▼]The phase behaviour of carbon dioxide/propargylic alcohols and carbon dioxide/oxetanes mixtures has been investigated using in-situ FTIR microspectrometry that allows us determining the evolution of the concentration of each component in the liquid phase as a function of temperature and pressure. It was at the same time possible to look inside the cell and to visualize the expansion of the liquid phase during the increase of the pressure. The measurements were performed at three different temperatures (40, 70 and 100◦C) for pressures ranging between 0.1 and 15 MPa. Propargylic alcohol (PA), 2-methyl-3-butyn-2-ol (MBOL), 3-butyn-1-ol (BOL) and trimethylene oxide (TMO) were selected as these molecules are used in the synthesis of cyclic or polycarbonates by coupling with CO2. Thus, we determined the CO2 sorption and the concentration of the substrate in the liquid phase. Thanks to these measurements, we established the pressure-composition phase diagram for the liquid phase of these substrate/CO2 binary mixtures. [less ▲]Detailed reference viewed: 17 (6 ULg) La collaboration entre architectes et plasticiens à Liège dans les années 1930.Charlier, Sébastien in In Situ, revue des patrimoines (in press), 26En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales ... [more ▼]En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales, le mensuel revendique une vision transversale de l’architecture où la réflexion plastique occupe une place centrale. Dès le départ, elle s’associe à Anthologie, revue imprégnée des théories futuristes et qui diffuse les artistes de l’avant-garde locale. D’abord par le biais de l’édition et des expositions, plasticiens et architectes travaillent ensuite ensemble dans le cadre de projets ambitieux financés par les pouvoirs publics. Cette contribution revient aux racines de cette collaboration en définissant les liens théoriques ou personnels unissant les deux revues. En se concentrant sur les infrastructures publiques, elle comment les artistes et les architectes ont répondu ensemble aux exigences concrètes de la commande en les replaçant dans le contexte social, politique et économique d’une ville belge de seconde importance à la veille de la Seconde Guerre mondiale. [less ▲]Detailed reference viewed: 85 (20 ULg) A Piano Made in Australia: Reinventing an Emblem of Cultural Wealth in Murray Bail's The VoyageHerbillon, Marie in Antipodes: A Global Journal of Australian/New Zealand Literature (in press), 31(2), Detailed reference viewed: 30 (4 ULg) Discussion of: Laboratory Study on 3D Flow Structures Induced by Zero-Height Side Weir and Implications for 1D ModelingRifai, Ismail ; Erpicum, Sébastien ; Archambeau, Pierre et alin Journal of Hydraulic Engineering (in press)Detailed reference viewed: 52 (15 ULg) Chondrocyte secretome: a source of novel insights and exploratory biomarkers of osteoarthritisSanchez, Christelle ; Bay-Jensen, Anne-Christine; Pap, Thomas et alin Osteoarthritis and Cartilage (in press)Detailed reference viewed: 40 (4 ULg) Complications of paediatric parenteral nutritionDecsi, T; Hartman, C; Simchowitz, V et alin Clinical Nutrition (in press)Detailed reference viewed: 12 (2 ULg) Multivariate analysis of 18F-DMFP PET data to assist the diagnosis of parkinsonismSegovia, Fermin; Gorriz, Juan M.; Ramirez, Javier et alin Frontiers in Neuroinformatics (in press)Detailed reference viewed: 46 (4 ULg) The clinical relevance of imatinib plasma trough concentrations in chronic myeloid leukemia. A Belgian studyVan Obbergh, F; Knoops, L; Devos, T et alin Clinical Biochemistry (in press)This retrospectivemulticenter study in patientswith chronic myeloid leukemia in chronic phasewas undertaken to confirm the clinical relevance of imatinib plasma concentrations monitoring in daily practice ... [more ▼]This retrospectivemulticenter study in patientswith chronic myeloid leukemia in chronic phasewas undertaken to confirm the clinical relevance of imatinib plasma concentrations monitoring in daily practice. Forty-one patients, with 47 imatinib plasma measurements, were analyzed during treatment with imatinib given at a fixed 400mg daily dose. A significant inverse relationship of imatinib concentration with the patients' weight was observed (Pearson's test: p=0.02,R2=0.1). More interestingly, patientswith poor response (switched to another tyrosine kinase inhibitor because of imatinib failure, or because of disease progression after an initial response) displayed a significantly lower mean imatinib concentration as compared to patients maintained on imatinib (822 ng/mL vs 1099 ng/mL; Student's t-test, p=0.04). Failure or disease progression occurred more often in patients in the lowest quartile of imatinib concentrations compared to patients in the highest quartile (p = 0.02, logrank test). No correlation could be established with other biological or clinical parameter, including complete cytogenic response and majormolecular response. In conclusion: in patients treatedwith imatinib at a fixed daily dose of 400 mg, imatinib plasma concentrations decreased with increasing body weight and were lower in patients switched to another tyrosine kinase inhibitor due to imatinib failure. Systematic determination of imatinib plasma trough levels should be encouraged in such patients. [less ▲]Detailed reference viewed: 19 (0 ULg) New insight on Carboniferous (Viséan) brachiopods from eastern Tafilalt (Morocco)Mottequin, Bernard; Denayer, Julien ; Herbig, Hans-Georg et alin Geological Journal (in press)Detailed reference viewed: 15 (1 ULg) Crystallization and Gelation Behavior of Low- and High Melting Waxes in Rice Bran Oil: a Case-Study on Berry Wax and Sunflower WaxDoan, Chi Diem; Tavernier, Iris; Bin Sintang, Mohd Dona et alin Food Biophysics (in press)Low-melting berry wax (BEW) has proven to be a good oil gelator with a positive contribution to the consistency and flexibility of the structured oil. Nevertheless, the properties of BEWand the ... [more ▼]Low-melting berry wax (BEW) has proven to be a good oil gelator with a positive contribution to the consistency and flexibility of the structured oil. Nevertheless, the properties of BEWand the corresponding oleogel have not yet been investigated in-depth. In this research, the difference in crystallization and gelling behavior between sunflower wax (SW), a high melting wax, and BEW, a low-melting wax, in rice bran oil (RBO) was investigated. The difference in melting and crystallization temperatures can be explained by the different chemical composition (long-chain wax esters in SWand shortchain fatty acids in BEW). The heterogeneity in crystal habits (unidirectional platelets versus microcrystalline particles) and polymorphism (orthorhombic versus hexagonal) are responsible for the varying gel strength and hardness of the respective SWand BEW-oleogels. The microcrystalline BEW particles aligned and reorganized during 1-month storage at 5 °C, which leaded to an increase in the gel strength and hardness of BEW-oleogel. The gelling property of SW-oleogel however did not significantly differ after 4 weeks at 5 °C, despite of the appearance of spherulitic crystalline clusters. The changes in the physical properties of wax-based oleogels during storage time were further explored using differential scanning calorimetry, polarized light microscope, powder X-ray diffraction and rheology. [less ▲]Detailed reference viewed: 29 (3 ULg) Virucidal efficacy of a hydrogen peroxyde nebulization against murine norovirus and feline calicivirus, two surrogates of human norovirusZonta, William; Mauroy, Axel ; Farnir, Frédéric et alin Food and Environmental Virology (in press), 8Detailed reference viewed: 17 (5 ULg) Overtopping induced failure of non-cohesive, homogenous fluvial dikesRifai, Ismail ; Erpicum, Sébastien ; Archambeau, Pierre et alin Water Resources Research (in press)Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of ... [more ▼]Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of sand-filled fluvial dikes were performed, considering a flow parallel to the dike axis. The breach was triggered by overtopping of the dike crest. A detailed monitoring of the transient evolution of the breach geometry was conducted, providing key insights into the gradual and complex processes involved in fluvial dike failure. The breach develops in two phases: (1) the breach becomes gradually wider and deeper eroding on the downstream side along the main channel, and (2) breach widening controlled by side slope failures, continuing in the downstream direction only. Increasing the inflow discharge in the main channel, the breach formation time decreases significantly and the erosion occurs preferentially on the downstream side. The downstream boundary condition has a strong influence on the breach geometry and the resulting outflow hydrograph. [less ▲]Detailed reference viewed: 32 (4 ULg) Fair Trade Milk Initiative in Belgium: Bricolage as an Empowering Strategy for ChangeFeyereisen, Marlène ; Stassart, Pierre M ; Melard, François in Sociologia Ruralis (in press)In a context of multiple crises, dairy farmers struggle to receive a fair remuneration for their work. This situation led to the creation of fair milk projects in Europe. But fair trade projects often ... [more ▼]In a context of multiple crises, dairy farmers struggle to receive a fair remuneration for their work. This situation led to the creation of fair milk projects in Europe. But fair trade projects often suffer from ambiguous interpretations that place them simultaneously in and against the market. This study focuses on a Belgian milk label in order to analyse how dairy farmers developed a particular strategy to create their own fair milk. Based on semi-structured interviews and using the multi-level perspective, we propose that articulating the concepts of lock-ins, bricolage and ambiguity enables us to analyse the potential of this innovation for the transition of the Belgian dairy system. The study shows that fairness is often a matter of divergent interpretations, and its final actualisation is the product of emergent and negotiated relations. By using bricolage practices, the stakeholders reinforced their capacity to gain market power and act within the system they want to change. [less ▲]Detailed reference viewed: 33 (8 ULg) A component method for cold-formed steel beam-to-column bolted gusset plate jointsBucmys, Zilvinas; Daniunas, Alfonsas; Jaspart, Jean-Pierre et alin Thin-Walled Structures (in press)Cold-formed steel elements are being used more frequently on construction sites because of the good strength-to-cost ratio. However, insufficient studies are published examining the properties of these ... [more ▼]Cold-formed steel elements are being used more frequently on construction sites because of the good strength-to-cost ratio. However, insufficient studies are published examining the properties of these constructions. This paper presents a study of cold formed steel bolted gusset plate connections. A “three springs” mechanical model to calculate joint stiffness is presented. Then the results predicted through the proposed model are validated through comparisons to experimental and finite element results. [less ▲]Detailed reference viewed: 59 (7 ULg) Brentano’s epistemology of history: inner experience and the reality of the pastBoccaccini, Federico in Perspectives on Science (2018)Detailed reference viewed: 21 (1 ULg) Défendre l’image de la Belgique à l’étranger. Quatorze lettres et notes inédites d’Eugène Beyens, Paul Hymans et Georges Lorand (1915-1919)Genin, Vincent in Bulletin de la Commission Royale d'Histoire (2018)Detailed reference viewed: 20 (0 ULg) From Ontology to Psychoanalysis. Benussi and Musatti on the Concept of Mental RealityBoccaccini, Federico in Meinong Studies / Meinong Studien (2018), 9Detailed reference viewed: 24 (0 ULg) Determination of phenolic organohalogens in human serum from a Belgian population and assessment of parameters affecting the human contaminationDufour, Patrice ; PIRARD, Catherine ; CHARLIER, Corinne in Science of the Total Environment (2017), 599-600Many in vitro or in vivo studies highlighted the potential deleterious effects of phenolic organohalogenated compounds (POHs) on the health, particularly on the thyroid system homeostasis, however few ... [more ▼]Many in vitro or in vivo studies highlighted the potential deleterious effects of phenolic organohalogenated compounds (POHs) on the health, particularly on the thyroid system homeostasis, however few large scale human epidemiological studies have been carried out, especially in Europe. Further studies monitoring the human contamination by POHs, the sources of exposure and the influence of these compounds on thyroid health are still needed. Therefore we determined the concentrations of 16 POHs (pentachlorophenol (PCP), tetrabromobisphenol A (TBBPA), 4 bromophenols (BPs), 3 hydroxy-polybromodiphenylethers (OH-PBDEs) and 7 hydroxy-polychlorobiphenyls (OH-PCBs)) in serum from 274 people aged from 18 to 76 years old living in Liege (Belgium) and the surrounding area. A questionnaire about their alimentary habits, life style and home environment was also administered to the volunteers. The predominant compound measured in the population was PCP (median concentration of 593.0 pg mL−1). 4-OH-CB 107, 4-OH-CB 146 and 4-OH-CB 187 were detected in all samples and contributed for 75% of the sum of OH-PCBs (ΣOH-PCBs). The median measured in our population for ΣOH-PCBs was 143.7 pg mL−1. TBBPA and 2,4,6-tribromophenol were detected in 31% and 63.8% of the samples respectively while the detection frequency observed for the other BPs and the OH-PBDEs was close to zero. We computed multivariate regression models in order to assess the influence of demographic and lifestyle parameters on the PCP and ΣOH-PCBs contamination levels. Significant correlation was found between the PCP concentration and sex, smoker status, sea fish consumption and level of education, although the model seemed to be a poor (R2 = 0.14) predictor of the PCP concentration. The model computed for ΣOHPCBs was more explanatory (R2 = 0.61) and involved age, BMI and sea fish consumption. Finally, we assessed the parameters affecting the ΣOH-PCBs/ΣPCBs ratio. The model proposed involved age, BMI, smoker status and parent PCB level, and explained 41% of the variability of the ΣOH-PCBs/ΣPCBs ratio. [less ▲]Detailed reference viewed: 22 (6 ULg) Albertina, más viva que muertaDubois, Jacques ; Mogollon Zapata, Juan Manuel in Revista Linguística y Literatura (2017), 72(2), Detailed reference viewed: 28 (0 ULg) The review of Audiovisual Media Services Directive: many political voices for one digital Europe?Vlassis, Antonios in Politique Européenne (2017)Detailed reference viewed: 18 (1 ULg) Du texte à la pratique : pour une sémiotique expérimentaleDondero, Maria Giulia in Semiotica (2017), 218Our essay aims at continuing the work of Jacques Fontanille, who developed a Semiotics of Practice next to a Semiotics of Text. This work, and especially Pratiques sémiotiques (2008), takes up a problem ... [more ▼]Our essay aims at continuing the work of Jacques Fontanille, who developed a Semiotics of Practice next to a Semiotics of Text. This work, and especially Pratiques sémiotiques (2008), takes up a problem already formulated by Jean-Marie Floch in the article « Êtes-vous arpenteurs ou somnambules ? L’élaboration d’une typologie comportementale des voyageurs du métro » (1990). We will initially retrace the debate about the epistemological relationship between text and practice, outlining the forms of enunciative praxis. Secondly, we propose the concept of we will consider the visualization that we call ‘notation’: this analytical form of mediation between text and practice does not have the same status of in-vivo textualisations, but it works like an ex-post reconstruction which highlights the main gestures and exchanges while performing their grammaticalization. A more general aim of this essay is an enquiry into the legitimate objects of textual semiotics: what are the objects that it can analyze without betraying its principle of immanence, but also without being unable to analyze practice [less ▲]Detailed reference viewed: 18 (3 ULg) Impact of spatio-temporal shade dynamics on wheat growth and yield, perspectives for temperate agroforestryArtru, Sidonie ; Garré, Sarah ; Dupraz, Christian et alin European Journal of Agronomy (2017)A stumbling block to the adoption of silvoarable agroforestry systems is the lack of quantitative knowledge on the performance of different crops when competing for resources with trees. In North-Western ... [more ▼]A stumbling block to the adoption of silvoarable agroforestry systems is the lack of quantitative knowledge on the performance of different crops when competing for resources with trees. In North-Western Europe, light is likely to be the principal limiting resource for understorey crops, and most agronomic studies show a systematic reduction of final yield as shade increases. However the intensity of the crop response depends on both the environmental conditions and the shade characteristics. This study addressed the issue by monitoring winter wheat (Triticum aestivum L.) growth, productivity and quality under artificial shade provided by military camouflage shade-netting, and using the Hi-sAFe model to relate the artificial shade conditions to those applying in agroforestry systems. The field experiment was carried out over two consecutive years (2013–14 and 2014–15) on the experimental farm of Gembloux Agro-Bio Tech, Belgium. The shade structures recreated two shade conditions: periodic shade (PS) and continuous shade (CS), with the former using overlapping military camouflage netting to provide discontinuous light through the day, and the latter using conventional shade cloth. The experiment simulated shading from a canopy of late-flushing hybrid walnut leaves above winter wheat. Shading was imposed 16 (2013–14) and 10 (2014–15) days before flowering and retained until harvest. The crop experienced full light conditions until the maximum leaf area index stage (LAImax) had been reached. In both years, LAI followed the same dynamics between the different treatments, but in 2013–2014 an attack of the take-all disease (Gaeumannomyces graminis var. tritici) reduced yields overall and prevented significant treatment effects. In season 2014–15 the decrease in global radiation reaching the crop during a period of 66 days (CS: – 61% and PS: – 43%) significantly affected final yield (CS: – 45% and PS: – 25%), mainly through a reduction of the average grain weight and the number of grain per m2. Grain protein content increased by up to 45% under the CS treatment in 2015. Nevertheless, at the plot scale, protein yield (t/ha) did not compensate for the final grain yield decrease. The Hi-sAFe model was used to simulate an agroforestry plot with two lines of walnut trees running either north-south or east-west. The levels of artificial shade levels applied in this experiment were compared to those predicted beneath trees growing with similar climatic conditions in Belgium. The levels used in the CS treatment are only likely to occur real agroforestry conditions on 10% of the cropped area until the trees are 30 years old and only with east-west tree row orientation. [less ▲]Detailed reference viewed: 44 (5 ULg) Tree species and time since afforestation drive soil C and N mineralization on former croplandRahman, Md Masudur ; Bàrcena, Teresa G; Vesterdal, Lin Geoderma (2017), 305Conversion from agriculture to forestry is considered a measure for mitigation of atmospheric CO2 but the impacts on soil C and N processes remain still unclear. We investigated heterotrophic respiration ... [more ▼]Conversion from agriculture to forestry is considered a measure for mitigation of atmospheric CO2 but the impacts on soil C and N processes remain still unclear. We investigated heterotrophic respiration (RH), specific carbon mineralization (CMIN) and nitrogen mineralization (NMIN) in Norway spruce (Picea abies (Karst.) L.) and oak (Quercus robur L.) chronosequences on former cropland by laboratory incubation. The RH was estimated as the release of C per gram soil and CMIN as the release of C per gram of soil organic matter (SOM). Seven Norway spruce stands (16–44 years), eight oak stands (4–43 years), a cropland, a 35 years old permanent pasture and a 200-year-old oak-dominated forest were sampled (0–5 cm and 5–15 cm soil layers) in early spring. The SOM content gradually increased with stand age in 0–5 cm but remained the same in the 5–15 cm soil layer. The RH in the 0–5 cm layer gradually increased with time since afforestation in both tree species while there was no change in CMIN. In 5–15 cm, neither RH nor CMIN changed significantly after afforestation, but oak stands had significantly higher RH than Norway spruce. The NMIN and nitrification in 0–5 cm significantly increased with stand age and only nitrification was higher in oak. In 5–15 cm, only NMIN in oak increased with stand age, but both NMIN and nitrification were significantly higher in oak than spruce. Cropland RH, CMIN and NMIN rates were comparable to those found within the first decades of afforestation, whereas the 200-year-old forest and the pasture generally had RH and NMIN rates similar to the older chronosequence stands. We conclude that potential RH and soil N mineralization increased with time since afforestation and were tree species specific. Soil organic C stock gains observed in this area during the first 45 years after afforestation were not driven by decreased SOM decomposability, leaving increased litter C inputs as a more likely explanation. The lower CMIN in the 200-year-old forest suggests that future studies should include older forests to assess if the stability of C and the retention of N may increase in a longer term perspective. [less ▲]Detailed reference viewed: 17 (2 ULg) L’événement énonciatif en sémiotique de l’image : de Roland Barthes à la sémiotique tensiveDondero, Maria Giulia ; Colas-Blaise, Marionin La part de l'oeil (2017), 31Dans cet article, nous visons à montrer que la sémiotique tensive développée par Zilberberg permet de revisiter utilement les notions barthésiennes de studium et de punctum et, leur permet de surcroît, de ... [more ▼]Dans cet article, nous visons à montrer que la sémiotique tensive développée par Zilberberg permet de revisiter utilement les notions barthésiennes de studium et de punctum et, leur permet de surcroît, de devenir un outil pour l’analyse de l’image. [less ▲]Detailed reference viewed: 16 (0 ULg) Analysis of definitions of General Practice/Family Medicine and Primary Health CareJamoulle, Marc ; Resnick, Melissa; Ittoo, Ashwin et alin British Journal of General Practice (2017)Abstract Background There are numerous definitions of General Practice and Family Medicine (GP/FM) and Primary Health Care (PHC), but the distinction between the two concepts is unclear. Aim To conduct a ... [more ▼]Abstract Background There are numerous definitions of General Practice and Family Medicine (GP/FM) and Primary Health Care (PHC), but the distinction between the two concepts is unclear. Aim To conduct a terminological analysis of a set of definitions of GP/FM and of PHC, to clarify what binds and what distinguishes these two concepts. Design The terms of 20 definitions were collected in two bags of words (one for GP/FM and one for PHC terms). A terminological analysis of these two bags of words was performed to prioritize the terms and analyze their world of reference. Methods The two collected bags of words were extracted with Vocabgrabber®, configured in two term butts using Wordle®, and further explored for similarities using Tropes®. The prioritized terms were analyzed using the Aristotelian approach to categorization of things. Results Although continuity of care (with person-centered approach and shared decision making) is the central issue of the two sets, the two sets of definitions differ greatly in content. The prioritized terms specific to GP/FM (community, medicine, responsibility, individual, problem, needs, ...) are different from prioritized terms specific to PHC (home, team, promotion, collaborator, engagement, neighborhood, medical center…). Conclusion Terminological analysis of the definitions for GP/FM and PHC shows two entities which are overlapping but distinct, necessitating a different taxonomic approach and different bibliographic search strategies. [less ▲]Detailed reference viewed: 227 (3 ULg) New computational method of the ball/race contacts transverse loads of high speed ball bearings without race control hypothesisServais, Christophe ; Bozet, Jean-Luc in Tribology International (2017), 113Some hypotheses are still necessary in order to access the ball bearing Newtonian equilibrium with quasi-static methods. Among these hypotheses are the values of the transverse loads within ball/race ... [more ▼]Some hypotheses are still necessary in order to access the ball bearing Newtonian equilibrium with quasi-static methods. Among these hypotheses are the values of the transverse loads within ball/race contacts. Those loads are due to the gyroscopic torques. Nowadays, the transverse loads are estimated without any equilibrium criterion by the specialized literature. Moreover, the race control assumption is often employed in addition to the hypotheses made about the transverse loads. The paper describes a new method to compute the transverse loads without using the race control assumption. Then, a correlation between the ball bearing kinematics and the transverse loads is established. It leads to an accurate and efficient computational method to access the Newtonian equilibrium of high speed ball bearings. [less ▲]Detailed reference viewed: 29 (5 ULg) Brentano, la théorie des catégories et la définition de la substanceBoccaccini, Federico in Etudes Philosophiques (2017)Detailed reference viewed: 32 (0 ULg) The Semiotics of Design in Media Visualization: Mereology and Observation StrategiesDondero, Maria Giulia in Information Design Journal (2017), 32(2), The purpose of this paper is to discern in what ways the semiotic methods of the Post- Greimasian French structuralist and the American Peircian traditions can enrich the study of contemporary methods of ... [more ▼]The purpose of this paper is to discern in what ways the semiotic methods of the Post- Greimasian French structuralist and the American Peircian traditions can enrich the study of contemporary methods of computational analysis of culture, particularly in the field of Cultural Analytics as implemented by the Russian Art Historian and Computer Scientist Lev Manovich. These semiotic approaches will be helpful in understanding what kinds of visualizations are being generated for use in Cultural Analytics, and what kinds of operations the observer must perform in order to experiment with scientific visualizations of this information. [less ▲]Detailed reference viewed: 61 (5 ULg) 3D thermal finite element analysis of laser cladding processed Ti-6Al-4V part with microstructural correlationsTran, Hoang Son ; Tchuindjang, Jérôme Tchoufack ; Paydas, Hakan et alin Materials & Design (2017), 128In this study, a 3D thermal model of laser cladding by powder injection applied to Ti-6Al-4V is developed. The manufactured part is made of a Ti-6Al-4V substrate on which successive layers of laser melted ... [more ▼]In this study, a 3D thermal model of laser cladding by powder injection applied to Ti-6Al-4V is developed. The manufactured part is made of a Ti-6Al-4V substrate on which successive layers of laser melted powder are added, leading to a thick deposit. The computed temperature field and its time evolution are compared to experimental measurements. The temperature distribution in the substrate allows the prediction of the depths of the melt pool and the heat affected zone. Correlations between simulated thermal histories and the final microstructure in the thick deposit are established, leading to the enhancement of a dynamic shift of the critical transformation points due to high thermal rates during laser processing. The nature of the phases present within the deposit is discussed. [less ▲]Detailed reference viewed: 43 (15 ULg) Exergy analysis applied to performance of buildings in EuropeSartor, Kevin ; Dewallef, Pierre in Energy and Buildings (2017), 148Energy performance of buildings generally assesses the energy consumption of buildings such as heating, domestic heat water, ventilation systems, etc. However, this approach is based on the first law of ... [more ▼]Energy performance of buildings generally assesses the energy consumption of buildings such as heating, domestic heat water, ventilation systems, etc. However, this approach is based on the first law of thermodynamics and considers only the quantity of energy used without considering its ‘quality’ and leads to a lack of information about the energy conversion processes. This is particularly true in the new low-energy buildings where sometimes high temperatures sources are used to meet low-temperature needs. The exergy analysis of a system, based on first and second thermodynamic laws, can be used to overcome this. In this work, it is proposed to compare the energy and the exergy consumption and the related CO2 emissions of several kinds of buildings to determine the best systems in terms of energy and exergy needs. The energy demand calculations are performed using the official software available in Belgium and some assumptions are implemented to consider the exergy approach. As exergy calculations require a reference state, some different climatic conditions are also investigated. Finally, some conclusions are discussed to rank the sources of energy and their related exergy losses. [less ▲]Detailed reference viewed: 15 (5 ULg) Similarity of the Jovian satellite footprints: spots multiplicity and dynamicsBonfond, Bertrand ; Grodent, Denis ; Badman, S. V. et alin Icarus (2017), 292(2017), 208217In the magnetospheres of Jupiter and Saturn, the intense interaction of the satellites Io, Europa, Ganymede and Enceladus with their surrounding plasma environment leaves a signature in the aurora of the ... [more ▼]In the magnetospheres of Jupiter and Saturn, the intense interaction of the satellites Io, Europa, Ganymede and Enceladus with their surrounding plasma environment leaves a signature in the aurora of the planet. Called satellite footprints, these auroral features appear either as a single spot (Europa and Enceladus) or as multiple spots (Io and Ganymede). Moreover, they can be followed by extended trailing tails in the case of Io and Europa, while no tail has been reported for Ganymede and Enceladus, yet. Here we show that all Jovian footprints can be made of several spots. Furthermore, the footprints all experience brightness variations on timescale of 2-3 minutes. We also demonstrate that the satellite location relative to the plasma sheet is not the only driver for the footprint brightness, but that the plasma environment and the magnetic field strength also play a role. These new findings demonstrate that the Europa and Ganymede footprints are very similar to the Io footprint. As a consequence, the processes expected to take place at Io, such as the bi-directional electron acceleration by Alfvén waves or the partial reflection of these waves on plasma density gradients, can most likely be extended to the other footprints, suggesting that they are indeed universal processes. [less ▲]Detailed reference viewed: 64 (14 ULg) Regiospecific radiolabelling of Nanofitin on Ni Magnetic Beads with [18F]FBEM and in vivo PET studiesDammicco, Sylvestre ; Goux, Marine; Lemaire, Christian et alin Nuclear Medicine & Biology (2017)Introduction: Nanofitins are low molecular weight, single chain and cysteine-free protein scaffolds able to selectively bind a defined biological target. They derive from Sac7d bacterial protein family ... [more ▼]Introduction: Nanofitins are low molecular weight, single chain and cysteine-free protein scaffolds able to selectively bind a defined biological target. They derive from Sac7d bacterial protein family and are highly stable over a wide range of pH (0-13) and temperature (Tm ~80°C). Their extreme stability, low cost of production and high tolerability for chemical coupling make Nanofitins a very interesting alternative to antibodies and their fragments. Here, a hexahistidine tagged model Nanofitin (H4) directed against hen egg white lysozyme was radiolabelled and injected in mice to provide a baseline biodistribution and pharmacokinetic profiles to support future Nanofitin development programs. Method: A single cysteine residue has been genetically inserted in a model Nanofitin and its regioselective radiolabelling has been performed with 4-[18F]fluorobenzamido-N-ethylamino-maleimide ([18F]FBEM). The synthesis of [18F]FBEM has been completely implemented on a radiosynthesis unit (FastLab) including HPLC purification and formulation. Coupling with the [18F]FBEM has been achieved on a solid support (Ni magnetic beads) allowing rapid purification at room temperature without organic solvent. PET-MRI studies on C57BL/6 mice were conducted after injection of [18F]FBEM-Cys-H4 in order to access the biodistribution of this Nanofitin model. Results: Radiochemical yield (decay corrected) of 54±7% (n=4) was obtained after optimization for coupling the [18F]FBEM to Nanofitin. Pharmacokinetics results of [18F]FBEM-Cys-H4 revealed a fast clearance through the liver and the kidneys. Conclusion: An efficient new method on Ni magnetic beads was developed to radiolabelled his-tagged biomolecules with [18F]FBEM. This procedure was applied on a Nanofitin model Cys-H4 and biodistribution kinetic studies were achieved to evaluate the potential use of Nanofitin for diagnostic imaging. Fast clearance indicates that Nanofitins represent very interesting tools for diagnostic imaging. [less ▲]Detailed reference viewed: 31 (6 ULg) Probing the atmosphere of a sub-Jovian planet orbiting a cool dwarfSedaghati, Elyar; Boffin, Henri M. J.; Delrez, Laetitia et alin Monthly Notices of the Royal Astronomical Society (2017), 468We derive the 0.01 $\mu$m binned transmission spectrum, between 0.74 and 1.0 $\mu$m, of WASP-80b from low resolution spectra obtained with the FORS2 instrument attached to ESO's Very Large Telescope. The ... [more ▼]We derive the 0.01 $\mu$m binned transmission spectrum, between 0.74 and 1.0 $\mu$m, of WASP-80b from low resolution spectra obtained with the FORS2 instrument attached to ESO's Very Large Telescope. The combination of the fact that WASP-80 is an active star, together with instrumental and telluric factors, introduces correlated noise in the observed transit light curves, which we treat quantitatively using Gaussian Processes. Comparison of our results together with those from previous studies, to theoretically calculated models reveals an equilibrium temperature in agreement with the previously measured value of 825K, and a sub-solar metallicity, as well as an atmosphere depleted of molecular species with absorption bands in the IR ($\gg 5\sigma$). Our transmission spectrum alone shows evidence for additional absorption from the potassium core and wing, whereby its presence is detected from analysis of narrow 0.003 $\mu$m bin light curves ($\gg 5\sigma$). Further observations with visible and near-UV filters will be required to expand this spectrum and provide more in-depth knowledge of the atmosphere. These detections are only made possible through an instrument-dependent baseline model and a careful analysis of systematics in the data. [less ▲]Detailed reference viewed: 6 (0 ULg) H0LiCOW - I. H0 Lenses in COSMOGRAIL's Wellspring: program overviewSuyu, S. H.; Bonvin, V.; Courbin, F. et alin Monthly Notices of the Royal Astronomical Society (2017), 468Strong gravitational lens systems with time delays between the multiple images allow measurements of time-delay distances, which are primarily sensitive to the Hubble constant that is key to probing dark ... [more ▼]Strong gravitational lens systems with time delays between the multiple images allow measurements of time-delay distances, which are primarily sensitive to the Hubble constant that is key to probing dark energy, neutrino physics and the spatial curvature of the Universe, as well as discovering new physics. We present H0LiCOW (H[SUB]0[/SUB] Lenses in COSMOGRAIL's Wellspring), a program that aims to measure H[SUB]0[/SUB] with <3.5 per cent uncertainty from five lens systems (B1608+656, RXJ1131-1231, HE 0435-1223, WFI2033-4723 and HE 1104-1805). We have been acquiring (1) time delays through COSMOGRAIL and Very Large Array monitoring, (2) high-resolution Hubble Space Telescope imaging for the lens mass modelling, (3) wide-field imaging and spectroscopy to characterize the lens environment and (4) moderate-resolution spectroscopy to obtain the stellar velocity dispersion of the lenses for mass modelling. In cosmological models with one-parameter extension to flat Λ cold dark matter, we expect to measure H[SUB]0[/SUB] to <3.5 per cent in most models, spatial curvature Ω[SUB]k[/SUB] to 0.004, w to 0.14 and the effective number of neutrino species to 0.2 (1σ uncertainties) when combined with current cosmic microwave background (CMB) experiments. These are, respectively, a factor of ˜15, ˜2 and ˜1.5 tighter than CMB alone. Our data set will further enable us to study the stellar initial mass function of the lens galaxies, and the co-evolution of supermassive black holes and their host galaxies. This program will provide a foundation for extracting cosmological distances from the hundreds of time-delay lenses that are expected to be discovered in current and future surveys. [less ▲]Detailed reference viewed: 14 (0 ULg) Practical Trajectories of Parametric Tools in Small and Medium Architectural FirmsStals, Adeline ; Elsen, Catherine ; Jancart, Sylvie in CAAD Futures 2017 (2017)Detailed reference viewed: 56 (18 ULg) A Receding Horizon Approach to Incorporate Frequency Support into the AC/DC Converters of a Multi-Terminal DC GridPapangelis, Lampros ; Panciatici, Patrick; Debry, Marie-Sophie et alin Electric Power Systems Research (2017)This paper proposes a novel control scheme for provision of frequency support among asynchronous AC areas through HVDC grids. It is based on local controllers, each acting on a voltage source converter ... [more ▼]This paper proposes a novel control scheme for provision of frequency support among asynchronous AC areas through HVDC grids. It is based on local controllers, each acting on a voltage source converter, using local measurements only, and supporting frequency of the adjacent AC area after a significant disturbance. The new discrete control is combined with the existing DC voltage droop technique. The formulation, inspired of Receding Horizon Control, enables providing to the AC area the desired frequency support, while at the same time taking into account various constraints, such as maintaining the DC voltage between secure operating limits. Examples obtained from a test system with a five-terminal DC network connecting two asynchronous areas demonstrate the effectiveness and robustness of the proposed control scheme in various scenarios, with emphasis on component failures. [less ▲]Detailed reference viewed: 44 (19 ULg) Specular setsBerthé, Valérie; De Felice, Clelia; Delecroix, Vincent et alin Theoretical Computer Science (2017), 684Detailed reference viewed: 16 (2 ULg) Morphology Development and Mechanical Properties Variation during Cold-Drawing of Polyethylene-Clay Nanocomposite FibersCoppola, Bartolomeo ; Scarfato, Paola; Incarnato, Loredana et alin Polymers (2017), 9(6), 235-251In this work, the influence of composition and cold-drawing on nano- and micro-scale morphology and tensile mechanical properties of PE/organoclay nanocomposite fibers was investigated. Nanocomposites ... [more ▼]In this work, the influence of composition and cold-drawing on nano- and micro-scale morphology and tensile mechanical properties of PE/organoclay nanocomposite fibers was investigated. Nanocomposites were prepared by melt compounding in a twin-screw extruder, using a maleic anhydride grafted linear low density polyethylene (LLDPE–g–MA) and an organomodified montmorillonite (Dellite 67G) at three different loadings (3, 5 and 10 wt %). Fibers were produced by a single-screw extruder and drawn at five draw ratios (DRs): 7.25, 10, 13.5, 16 and 19. All nanocomposites, characterized by XRD, SEM, TEM, and FT-IR techniques, showed an intercalated/exfoliated morphology. The study evidenced that the nanoclay presence significantly increases both elastic modulus (up to +115% for fibers containing 10 wt % of D67G) and drawability of as-spun nanocomposite fibers. Moreover, at fixed nanocomposite composition, the cold-drawing process increases fibers elastic modulus and tensile strength at increasing DRs. However, at high DRs, “face-to-edge” rearrangement phenomena of clay layers (i.e., clay layers tend to rotate and touch each other) arise in fibers at high nanoclay loadings. Finally, nanocomposite fibers show a lower diameter reduction during drawing, with respect to the plain system, and surface feature of adjustable roughness by controlling the composition and the drawing conditions. [less ▲]Detailed reference viewed: 5 (0 ULg) Body shape convergence driven by small size optimum in marine angelfishesFrederich, Bruno ; Santini, Francesco; Konow, Nicolai et alin Biology Letters (2017), 13Convergent evolution of small body size occurs across many vertebrate clades and may reflect an evolutionary response to shared selective press- ures. However it remains unclear if other aspects of ... [more ▼]Convergent evolution of small body size occurs across many vertebrate clades and may reflect an evolutionary response to shared selective press- ures. However it remains unclear if other aspects of phenotype undergo convergent evolution in miniaturized lineages. Here we present a comparative analysis of body size and shape evolution in marine angelfishes (Pomacanthidae), a reef fish family characterized by repeated transitions to small body size. We ask if lineages that evolve small sizes show convergent evolution in body shape. Our results reveal that angelfish lineages evolved three different stable size optima with one corresponding to the group of pygmy angelfishes (Centropyge). Then, we test if the observed shifts in body size are associated with changes to new adaptive peaks in shape. Our data suggest that independent evolution to small size optima have induced repeated convergence upon deeper body and steeper head profile in Centropyge. These traits may favour manoeuvrability and visual aware- ness in these cryptic species living among corals, illustrating that functional demands on small size may be related to habitat specialization and predator avoidance. The absence of shape convergence in large marine angelfishes also suggests that more severe requirements exist for small than for large size optima. [less ▲]Detailed reference viewed: 24 (1 ULg) Comparison of UAS photogrammetric products for tree detection and characterization of coniferous standsBonnet, Stéphanie ; Lisein, Jonathan ; Lejeune, Philippe in International Journal of Remote Sensing (2017), 38(19), 5310-5337The use of Unmanned Aerial Systems (UAS) opens a new era for remote sensing and forest management, which requires accurate and regular quantification of resources. In this study, we propose a ... [more ▼]The use of Unmanned Aerial Systems (UAS) opens a new era for remote sensing and forest management, which requires accurate and regular quantification of resources. In this study, we propose a comprehensive workflow to detect trees and assess forest attributes in the particular context of coniferous stands in transformation from even-aged to uneven-aged stands, using UAS imagery, from data acquisition to model construction. We implement a local maxima detection to identify the tree tops, based on a fixed-radius moving window in a Canopy Height Model (CHM) and images produced from UAS surveys. To compare the contribution of different photogrammetric products, we analysed the local maxima detected from the CHM, from three image types (individual rectified and ortho-rectified images and ortho-mosaic) and from a combination of both CHM and images. The local maxima detection gave promising results, with low omission and true-positive rates of up to 89.2%. A filtering process of false positives was implemented, using a supervised classification which decreased the false positives up to 2.6%. Based on the local maxima combined with an area-based approach, we constructed models to assess top height (R2: 83%, root mean square error [RMSE]: 5.7%), number of stems (R2: 71%, RMSE: 28.3%), basal area (R2: 70%, RMSE: 16.2%), volume (R2: 69%, RMSE: 20.1%), and individual tree height (R2: 70%, RMSE: 7.2%). Despite a suboptimal data acquisition, our simple and flexible method has yielded good results and shows great potential for application. [less ▲]Detailed reference viewed: 12 (3 ULg) Methodological approach for the implementation of a simulator in augmented reality in a radiation therapy departmentServotte, Jean-Christophe ; Guillaume, Michèle ; BOGA, Deniz et alin International Journal of Healthcare Management (2017), 10(3), 154-159Radiation therapy (RT) is one of the cornerstones for the treatment of cancer. In most countries RT machines are handled by professionals benefitting from an ad hoc training in theoretical knowledge as ... [more ▼]Radiation therapy (RT) is one of the cornerstones for the treatment of cancer. In most countries RT machines are handled by professionals benefitting from an ad hoc training in theoretical knowledge as well as technical and non-technical skills. In Belgium, RT departments are hiring in nurses for this activity. In countries where there is a specified core curriculum for basic training of radiation technologist, this basic training falls short once in practice and there is an obvious requirement for a continuous updating of skills in order to keep up with the accelerating evolution of technology. Therefore, the decision has been taken to implement a simulator in augmented reality in the RT department in Liège, to face the double challenge i.e. basic professional training as well as continuous education in technical and nontechnical skills and Crew Resource Management. We describe a methodological approach to implement this simulator in augmented reality. [less ▲]Detailed reference viewed: 12 (1 ULg) Le principe non bis in idem et les procédures mixtes : un camouflet infligé à la jurisprudence Zalotoukhine ?Michiels, Olivier ; Falque, Géraldine in Revue de Jurisprudence de Liège, Mons et Bruxelles (2017), (2017/23), 1069-1078Pour lutter contre certains comportements socialement inacceptables, les États peuvent concevoir des réponses juridiques complémentaires au moyen de procédures mixtes pour autant que celles-ci forment un ... [more ▼]Pour lutter contre certains comportements socialement inacceptables, les États peuvent concevoir des réponses juridiques complémentaires au moyen de procédures mixtes pour autant que celles-ci forment un tout cohérent, c’est-à-dire qu’elles soient liées par un lien matériel et temporel suffisamment étroit. Le cumul des sanctions pénales et administratives est autorisé dès lors que les deux procédures poursuivent des buts complémentaires et traitent d’aspects différents de l’acte préjudiciable, que le cumul des sanctions soit prévisible, qu’il n’y ait pas de répétition dans la collecte et dans l’appréciation des preuves et qu’un mécanisme de compensation entre les sanctions soit prévu. [less ▲]Detailed reference viewed: 25 (3 ULg) SbCOMT (Bmr12) is involved in the biosynthesis of tricin-lignin in sorghumEudes, Aymerick; Dutta, Tanmoy; Deng, Kei et alin PLoS ONE (2017), 12(6), 1-11Lignin in plant biomass represents a target for engineering strategies towards the development of a sustainable bioeconomy. In addition to the conventional lignin monomers, namely p-coumaryl, coniferyl ... [more ▼]Lignin in plant biomass represents a target for engineering strategies towards the development of a sustainable bioeconomy. In addition to the conventional lignin monomers, namely p-coumaryl, coniferyl and sinapyl alcohols, tricin has been shown to be part of the native lignin polymer in certain monocot species. Because tricin is considered to initiate the polymerization of lignin chains, elucidating its biosynthesis and mechanism of export to the cell wall constitute novel challenges for the engineering of bioenergy crops. Late steps of tricin biosynthesis require two methylation reactions involving the pathway intermediate selgin. It has recently been demonstrated in rice and maize that caffeate O-methyltransferase (COMT) involved in the synthesis syringyl (S) lignin units derived from sinapyl alcohol also participates in the synthesis of tricin in planta. In this work, we validate in sorghum (Sorghum bicolor L.) that the O-methyltransferase responsible for the production of S lignin units (SbCOMT / Bmr12) is also involved in the synthesis of lignin-linked tricin. In particular, we show that biomass from the sorghum bmr12 mutant contains lower level of tricin incorporated into lignin, and that SbCOMT can methylate the tricin precursors luteolin and selgin. Our genetic and biochemical data point toward a general mechanism whereby COMT is involved in the synthesis of both tricin and S lignin units. [less ▲]Detailed reference viewed: 15 (0 ULg) Whole blood microsampling for the quantitation of estetrol without derivatization by liquid chromatography-tandem mass spectrometryNys, Gwenaël ; Gallez, Anne ; Kok, Miranda et alin Journal of Pharmaceutical & Biomedical Analysis (2017), 140Detailed reference viewed: 40 (21 ULg) L’article 458 du Code des impôts sur les revenus est-il un frein à l’intervention du fisc en procédure pénale ?Michiels, Olivier in Journal des Tribunaux (2017), 2017/21(n° 6691), 398-400L'article aborde la question de la constitution de partie civile de l'Etat, administration des contributions directes, en cas de fraude fiscale. Il envisage notamment ce sujet au regard de l'article 458 ... [more ▼]L'article aborde la question de la constitution de partie civile de l'Etat, administration des contributions directes, en cas de fraude fiscale. Il envisage notamment ce sujet au regard de l'article 458 du CIR qui prévoit que les personnes qui auront été condamnées comme auteurs ou complices d’infractions visées aux articles 449 à 452 du Code des impôts sur les revenus seront tenues solidairement au paiement de l’impôt éludé. [less ▲]Detailed reference viewed: 19 (3 ULg) Waste Heat Recovery by Means of Organic Rankine Cycle (ORC) System Coupled with Two-Phase Closed ThermosyphonsLe, Van Long ; Declaye, Sébastien ; Dumas, Xavier et alin International Journal of Thermodynamics (2017)This paper aims at assessing the performance of a waste heat-to-power plant by means of an ORC (Organic Rankine Cycle) system coupled with two-phase closed thermosyphons (or gravity-assisted heat pipes or ... [more ▼]This paper aims at assessing the performance of a waste heat-to-power plant by means of an ORC (Organic Rankine Cycle) system coupled with two-phase closed thermosyphons (or gravity-assisted heat pipes or wickless heat pipes). The heat exchanger, made up of two-phase closed thermosyphons, is used for conveying heat from exhaust stream to ORC working fluid. In reality, a hot oil loop or a pressurized hot water loop or a saturated ste am loop or even a direct evaporator is often used to transfer heat from the heat source to the ORC system. However, installing a heat exchanger directly in the hot gas paths of ORC system evokes the concerns for the flammability and/or toxicity of organic working fluids especially when the heat source has a relatively high temperature. Also the use of an intermediate heat carrier loop such as thermal oil or saturated steam or pressurized water loop is costly and involves installation of comparatively heavy components. In principle, the use of two-phase closed thermosyphons for capturing and transporting heat from a waste heat source to organic working fluid is less expensive than utilizing an intermediate heat transfer loop and eliminates safety issues as in the case of direct installation of an ORC evaporator in the hot gas paths. [less ▲]Detailed reference viewed: 13 (3 ULg) H0LiCOW - III. Quantifying the effect of mass along the line of sight to the gravitational lens HE 0435-1223 through weighted galaxy counts★Rusu, Cristian E.; Fassnacht, Christopher D.; Sluse, Dominique et alin Monthly Notices of the Royal Astronomical Society (2017), 467Based on spectroscopy and multiband wide-field observations of the gravitationally lensed quasar HE 0435-1223, we determine the probability distribution function of the external convergence κ[SUB]ext[/SUB ... [more ▼]Based on spectroscopy and multiband wide-field observations of the gravitationally lensed quasar HE 0435-1223, we determine the probability distribution function of the external convergence κ[SUB]ext[/SUB] for this system. We measure the under/overdensity of the line of sight towards the lens system and compare it to the average line of sight throughout the Universe, determined by using the CFHTLenS (The Canada France Hawaii Lensing Survey) as a control field. Aiming to constrain κ[SUB]ext[/SUB] as tightly as possible, we determine under/overdensities using various combinations of relevant informative weighting schemes for the galaxy counts, such as projected distance to the lens, redshift and stellar mass. We then convert the measured under/overdensities into a κ[SUB]ext[/SUB] distribution, using ray-tracing through the Millennium Simulation. We explore several limiting magnitudes and apertures, and account for systematic and statistical uncertainties relevant to the quality of the observational data, which we further test through simulations. Our most robust estimate of κ[SUB]ext[/SUB] has a median value κ^med_ext = 0.004 and a standard deviation σ[SUB]κ[/SUB] = 0.025. The measured σ[SUB]κ[/SUB] corresponds to 2.5 per cent relative uncertainty on the time delay distance, and hence the Hubble constant H[SUB]0[/SUB] inferred from this system. The median κ^med_ext value varies by ˜0.005 with the adopted aperture radius, limiting magnitude and weighting scheme, as long as the latter incorporates galaxy number counts, the projected distance to the main lens and a prior on the external shear obtained from mass modelling. This corresponds to just ˜0.5 per cent systematic impact on H[SUB]0[/SUB]. The availability of a well-constrained κ[SUB]ext[/SUB] makes HE 0435-1223 a valuable system for measuring cosmological parameters using strong gravitational lens time delays. [less ▲]Detailed reference viewed: 15 (1 ULg) Validation of MOPITT carbon monoxide using ground-based Fourier transform infrared spectrometer data from NDACCBuchholz, R. R.; Deeter, M. N.; Worden, H. M. et alin Atmospheric Measurement Techniques (2017), 10(5), 1927--1956The Measurements of Pollution in the Troposphere (MOPITT) satellite instrument provides the longest continuous dataset of carbon monoxide (CO) from space. We perform the first validation of MOPITT version ... [more ▼]The Measurements of Pollution in the Troposphere (MOPITT) satellite instrument provides the longest continuous dataset of carbon monoxide (CO) from space. We perform the first validation of MOPITT version 6 retrievals using total column CO measurements from ground-based remote-sensing Fourier transform infrared spectrometers (FTSs). Validation uses data recorded at 14 stations, that span a wide range of latitudes (80°N to 78°S), in the Network for the Detection of Atmospheric Composition Change (NDACC). MOPITT measurements are spatially co-located with each station, and different vertical sensitivities between instruments are accounted for by using MOPITT averaging kernels (AKs). All three MOPITT retrieval types are analyzed: thermal infrared (TIR-only), joint thermal and near infrared (TIR–NIR), and near infrared (NIR-only). Generally, MOPITT measurements overestimate CO relative to FTS measurements, but the bias is typically less than 10%. Mean bias is 2.4% for TIR-only, 5.1% for TIR–NIR, and 6.5% for NIR-only. The TIR–NIR and NIR-only products consistently produce a larger bias and lower correlation than the TIR-only. Validation performance of MOPITT for TIR-only and TIR–NIR retrievals over land or water scenes is equivalent. The four MOPITT detector element pixels are validated separately to account for their different uncertainty characteristics. Pixel 1 produces the highest standard deviation and lowest correlation for all three MOPITT products. However, for TIR-only and TIR–NIR, the error-weighted average that includes all four pixels often provides the best correlation, indicating compensating pixel biases and well-captured error characteristics. We find that MOPITT bias does not depend on latitude but rather is influenced by the proximity to rapidly changing atmospheric CO. MOPITT bias drift has been bound geographically to within ±0.5%/yr or lower at almost all locations. [less ▲]Detailed reference viewed: 34 (1 ULg) A seven-planet resonant chain in TRAPPIST-1Luger, Rodrigo; Sestovic, Marko; Kruse, Ethan et alin Nature Astronomy (2017), 1The TRAPPIST-1 system is the first transiting planet system found orbiting an ultracool dwarf star[SUP] 1 [/SUP]. At least seven planets similar in radius to Earth were previously found to transit this ... [more ▼]The TRAPPIST-1 system is the first transiting planet system found orbiting an ultracool dwarf star[SUP] 1 [/SUP]. At least seven planets similar in radius to Earth were previously found to transit this host star[SUP] 2 [/SUP]. Subsequently, TRAPPIST-1 was observed as part of the K2 mission and, with these new data, we report the measurement of an 18.77 day orbital period for the outermost transiting planet, TRAPPIST-1 h, which was previously unconstrained. This value matches our theoretical expectations based on Laplace relations[SUP] 3 [/SUP] and places TRAPPIST-1 h as the seventh member of a complex chain, with three-body resonances linking every member. We find that TRAPPIST-1 h has a radius of 0.752 R [SUB]⊕[/SUB] and an equilibrium temperature of 173 K. We have also measured the rotational period of the star to be 3.3 days and detected a number of flares consistent with a low-activity, middle-aged, late M dwarf. [less ▲]Detailed reference viewed: 5 (0 ULg) Electro dynamic fragmentation of printed wiring boards as a preparation tool for their recyclingMartino, Rémi; Iseli, Cedric; Gaydardzhiev, Stoyan et alin Minerals Engineering (2017), 107The use of Electro Dynamic Fragmentation (EDF) enables selective fragmentation of materials through generating electrical discharges as a means of fracturing. Liberated materials can be thus processed ... [more ▼]The use of Electro Dynamic Fragmentation (EDF) enables selective fragmentation of materials through generating electrical discharges as a means of fracturing. Liberated materials can be thus processed downstream in a more efficient way especially when value-added End-of-Life (EoL) electronic equipment is recycled. The aim of this study was to assess the benefits of the EDF technology towards processing of EoL printed wiring boards (PWBs) in view their recyclability. Printed wiring boards were comminuted using EDF at three different settings and with a hammer mill for comparative experiment. The products coming out were characterized by optical microscopy, SEM and liberation oriented leaching. Subsamples from the various EDF stages were inspected to investigate the progress of cracks and degree of copper layers exposure. The different energy levels used during the EDF processing have resulted in different degrees of PWBs damages, starting from components removal to entire structure perturbation and size reduction. EDF has resulted in generation of a lesser amount of fines, however the optimal approach in view energy efficient post-processing of the studied PWBs was the combination between single-stage EDF for components removal only with subsequent shredding of the depopulated boards. [less ▲]Detailed reference viewed: 54 (15 ULg) Period–luminosity relations of fast-rotating B-type stars in the young open cluster NGC 3766Saio, H.; Ekström, S.; Mowlavi, N. et alin Monthly Notices of the Royal Astronomical Society (2017), 467(4), 3864-3873We study the pulsational properties of rapidly rotating main-sequence B-type stars using linear non-adiabatic analysis of non-radial low-frequency modes taking into account the effect of rotation. We ... [more ▼]We study the pulsational properties of rapidly rotating main-sequence B-type stars using linear non-adiabatic analysis of non-radial low-frequency modes taking into account the effect of rotation. We compare the properties of prograde sectoral g and retrograde r modes excited by the κ mechanism at the Fe opacity peak with the newly discovered period–luminosity relation that is obeyed by a group of fast-rotating B-type stars in the young open cluster NGC 3766. The observed relation consists of two sequences in the period versus magnitude diagram, at periods shorter than 0.5 d. We find that this property is consistent with similar period–luminosity relations predicted for excited sectoral prograde g modes of azimuthal orders m = −1 and −2 in fast-rotating stars along an isochrone. We further show that some of the rapidly rotating stars that have photometric variability with periods longer than a day may be caused by r-mode pulsation predicted to be excited in these stars. One fast-rotating star, in particular, shows both short and long periods that can be explained by the simultaneous excitation of g- and r-mode pulsations in models of fast-rotating stars. [less ▲]Detailed reference viewed: 13 (3 ULg) EditorialDewals, Benjamin in Proceedings of ICE : Water Management (2017), 170(WM3), 109-110Detailed reference viewed: 7 (1 ULg) Evolution and diversity of ram-suction feeding in damselfishes (Pomacentridae)Olivier, Damien ; Gajdzik, Laura ; Parmentier, Eric et alin Organisms Diversity & Evolution (2017), 17The cerato-mandibular (c-md) ligament is a synapomorphy within Pomacentridae that creates a tight link between the lower jaws and the hyoid bars. However, this morphological trait has been secondarily ... [more ▼]The cerato-mandibular (c-md) ligament is a synapomorphy within Pomacentridae that creates a tight link between the lower jaws and the hyoid bars. However, this morphological trait has been secondarily lost in multiple lineages during evolution. A previous study revealed that the loss of this trait acted as a release of evolutionary constraints, leading to a cascade of morphological changes such elongated buccal jaws and a slender body. Ecomorphological interpretations suggested the loss of the c-md ligament has ultimately led to a new adaptive peak in zooplanktivory through an optimization of the ram feeding mode associated with a specialization in pelagic feeding. Here, we tested these hypotheses by comparing functional and diet diversity between damselfish species with and without the c-md ligament. Although species lacking the c-md ligament presented a conserved kinematic pattern resulting from high ram and low suction performances, our results did not support an optimization of the ram feeding mode. Indeed, some species with the c-md ligament showed the same or exceeded the ram performance of species without the c-md ligament. The species with the c-md ligament had a more diverse kinematic pattern exploring the entire ram-suction functional range in damselfishes. Finally, our results did not show any diet variations associated with the loss of the c-md ligament. Our study furthers the understanding of how a morphological trait has shaped, by its presence or absence, the ecomorpho-functional diversification of Pomacentridae. [less ▲]Detailed reference viewed: 32 (9 ULg) Mapping Soil Organic Carbon stocks and estimating uncertainties at the regional scale following a legacy sampling strategy (Southern Belgium, Wallonia)Chartin, Caroline; Stevens, Antoine; Goidts, Esther et alin Geoderma Regional (2017), 9The quantification and the spatialisation of reliable SOC stocks (Mg C ha− 1) and total stock (Tg C) baselines and associated uncertainties are fundamental to detect the gains or losses in SOC, and to ... [more ▼]The quantification and the spatialisation of reliable SOC stocks (Mg C ha− 1) and total stock (Tg C) baselines and associated uncertainties are fundamental to detect the gains or losses in SOC, and to locate sensitive areas with low SOC levels. Here, we aim to both quantify and spatialize SOC stocks at regional scale (southern Belgium) based on data from one non-design-based or model-based sampling scheme. To this end, we developed a computation procedure based on Digital Soil Mapping techniques and stochastic simulations (Monte-Carlo) allowing the estimation of multiple (here, 10,000) independent spatialized datasets. The computation of the prediction uncertainty accounts for the errors associated to both the estimations of i) SOC stocks and ii) parameters of the spatial model. Based on these 10,000 individuals, median SOC stocks and 90% prediction intervals were computed for each pixel, as well as total SOC stocks and their 90% prediction intervals for selected sub-areas and for the entire study area. Hence, a Generalised Additive Model (GAM) explaining 69.3% of the SOC stock variance was calibrated and then validated (R2 = 0.64). The model overestimated low SOC stock (below 50 Mg C ha− 1) and underestimated high SOC stock (especially those above 100 Mg C kg− 1). A positive gradient of SOC stock occurred from the northwest to the center of Wallonia with a slight decrease on the southernmost part, correlating to the evolution of precipitation and temperature (along with elevation) and dominant land use. At the catchment scale higher SOC stocks were predicted on valley bottoms, especially for poorly drained soils under grassland. Mean predicted SOC stocks for cropland and grassland in Wallonia were of 26.58 Tg C (SD 1.52) and 43.30 Tg C (2.93), respectively. The procedure developed here allowed to predict realistic spatial patterns of SOC stocks all over agricultural lands of southern Belgium and to produce reliable statistics of total SOC stocks for each of the 20 combinations of land use/agricultural regions of Wallonia. This procedure appears useful to produce soil maps as policy tools in conducting sustainable management at regional and national scales, and to compute statistics which comply with specific requirements of reporting activities. [less ▲]Detailed reference viewed: 35 (7 ULg) Genetic parameters of mid-infrared methane predictions and their relationships with milk production traits in Holstein cattleKandel, Purna; Vanrobays, Marie-Laure; Vanlierde, Amélie et alin Journal of Dairy Science (2017), 100(7), 5578-5591Many countries have pledged to reduce greenhouse gases. In this context, the dairy sector is one of the identified sectors to adapt production circumstances to address socio-environmental constraints due ... [more ▼]Many countries have pledged to reduce greenhouse gases. In this context, the dairy sector is one of the identified sectors to adapt production circumstances to address socio-environmental constraints due to its large carbon footprint related to CH4 emission. This study aimed mainly to estimate (1) the genetic parameters of 2 milk mid-infrared-based CH4 proxies [predicted daily CH4 emission (PME, g/d), and log-transformed predicted CH4 intensity (LMI)] and (2) their genetic correlations with milk production traits [milk (MY), fat (FY), and protein (PY) yields] from first- and second-parity Holstein cows. A total of 336,126 and 231,400 mid-infrared CH4 phenotypes were collected from 56,957 and 34,992 first- and second-parity cows, respectively. The PME increased from the first to the second lactation (433 vs. 453 g/d) and the LMI decreased (2.93 vs. 2.86). We used 20 bivariate random regression test-day models to estimate the variance components. Moderate heritability values were observed for both CH4 traits, and those values decreased slightly from the first to the second lactation (0.25 ± 0.01 and 0.22 ± 0.01 for PME; 0.18 ± 0.01 and 0.17 ± 0.02 for LMI). Lactation phenotypic and genetic correlations were negative between PME and MY in both first and second lactations (−0.07 vs. −0.07 and −0.19 vs. −0.24, respectively). More close scrutiny revealed that relative increase of PME was lower with high MY levels even reverting to decrease, and therefore explaining the negative correlations, indicating that higher producing cows could be a mitigation option for CH4 emission. The PME phenotypic correlations were almost equal to 0 with FY and PY for both lactations. However, the genetic correlations between PME and FY were slightly positive (0.11 and 0.12), whereas with PY the correlations were slightly negative (−0.05 and −0.04). Both phenotypic and genetic correlations between LMI and MY or PY or FY were always relatively highly negative (from −0.21 to −0.88). As the genetic correlations between PME and LMI were strong (0.71 and 0.72 in first and second lactation), the selection of one trait would also strongly influence the other trait. However, in animal breeding context, PME, as a direct quantity CH4 proxy, would be preferred to LMI, which is a ratio trait of PME with a trait already in the index. The range of PME sire estimated breeding values were 22.1 and 29.41 kg per lactation in first and second parity, respectively. Further studies must be conducted to evaluate the effect of the introduction of PME in a selection index on the other traits already included in this index, such as, for instance, fertility or longevity. [less ▲]Detailed reference viewed: 19 (1 ULg) Numerical modelling of micro-plasto-hydrodynamic lubrication in plane strip drawingCarretta, Yves ; Bech, Jakob; Legrand, Nicolas et alin Tribology International (2017), 110This paper presents a new finite element model capable of predicting the onset of micro-plasto-hydrodynamic (MPH) lubrication and the amount of lubricant escaping from surface pockets in metal forming ... [more ▼]This paper presents a new finite element model capable of predicting the onset of micro-plasto-hydrodynamic (MPH) lubrication and the amount of lubricant escaping from surface pockets in metal forming. The present approach is divided in two steps. First, a simulation at the macroscopic level is conducted. Then, a second simulation highlighting microscopic liquid lubrication mechanisms is achieved using boundary conditions provided by the first model. These fluid-structure interaction computations are made possible through the use of the Arbitrary Lagrangian Eulerian (ALE) formalism. The developed methodology is validated by comparison to experimental measurements conducted in plane strip drawing. The effect of physical parameters like the drawing speed, the die angle and the strip thickness reduction is investigated. The numerical results show good agreement with experiments. [less ▲]Detailed reference viewed: 41 (13 ULg) Percepire la sofferenza degli animali. Fondamenti per un’empatia interspecificaServais, Véronique in Animal Studies (2017), 17Detailed reference viewed: 15 (0 ULg) A decision support tool for transient stability preventive controlPertl, Michael; Weckesser, Johannes ; Rezkalla, Michel et alin Electric Power Systems Research (2017), 147The paper presents a decision support tool for transient stability preventive control contributing to increased situation awareness of control room operators by providing additional information about the ... [more ▼]The paper presents a decision support tool for transient stability preventive control contributing to increased situation awareness of control room operators by providing additional information about the state of the power system in terms of transient stability. A time-domain approach is used to assess the transient stability for potentially critical faults. Potential critical fault locations are identified by a critical bus screening through analysis of pre-disturbance steady-state conditions. The identified buses are subject to a fast critical contingency screening determining the actual critical contingencies/buses. These two screenings aim at reducing the computational burden of the assessment, since only contingencies considered as critical are taken into account. The critical clearing times for the critical contingencies are determined. A preventive re-dispatch of generators to ensure a predefined minimum critical clearing time for faults at all buses is proposed, while costs are minimized. The results of the assessment are presented to the control room operator, who decides to accept the suggested dispatch or to repeat the assessment considering additional user-specific constraints. The effectiveness of the proposed method is demonstrated on a standard nine-bus and the New England test system. [less ▲]Detailed reference viewed: 33 (7 ULg) A computational stochastic multiscale methodology for MEMS structures involving adhesive contactHoang Truong, Vinh ; Wu, Ling ; Paquay, Stéphane et alin Tribology International (2017), 110This work aims at developing a computational stochastic multiscale methodology to quantify the uncertainties of the adhesive contact problems due to capillary effects and van der Waals forces in MEMS ... [more ▼]This work aims at developing a computational stochastic multiscale methodology to quantify the uncertainties of the adhesive contact problems due to capillary effects and van der Waals forces in MEMS. Because the magnitudes of the adhesive forces strongly depend on the surface interaction distances, which in turn evolve with the roughness of the contacting surfaces, the involved structural behaviors suffer from a scatter. To numerically predict the probabilistic behaviors of structures involving adhesion, the proposed method introduces stochastic meso-scale random apparent contact forces which can be integrated into a stochastic finite element model. Because the evaluation of their realizations is expensive, a generator for the random apparent contact force using the polynomial chaos expansion is constructed in an efficient way. [less ▲]Detailed reference viewed: 147 (76 ULg) Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate ReceptorsLarsen, Anja Probst; Fièvre, Sabine; Frydenvang, Karla et alin Molecular Pharmacology (2017), 91Kainate receptors (KARs) consist of a class of ionotropic gluta- mate receptors, which exert diverse pre- and postsynaptic functions through complex signaling regulating the activity of neural circuits ... [more ▼]Kainate receptors (KARs) consist of a class of ionotropic gluta- mate receptors, which exert diverse pre- and postsynaptic functions through complex signaling regulating the activity of neural circuits. Whereas numerous small-molecule positive allosteric modulators of the ligand-binding domain of (S)-2- amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoic acid (AMPA) receptors have been reported, no such ligands are avail- able for KARs. In this study, we investigated the ability of three benzothiadiazine-based modulators to potentiate glutamate-evoked currents at recombinantly expressed KARs. 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1- dioxide (BPAM344) potentiated glutamate-evoked currents of GluK2a 21-fold at the highest concentration tested (200 mM), with an EC50 of 79 mM. BPAM344 markedly decreased desensitization kinetics (from 5.5 to 775 ms), whereas it only had a minor effect on deactivation kinetics. 4-cyclopropyl-7-hydroxy-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BPAM521) potentiated the recorded peak current amplitude of GluK2a 12-fold at a concen- tration of 300 mM with an EC50 value of 159 mM, whereas no potentiation of the glutamate-evoked response was observed for 7-chloro-4-(2-fluoroethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BPAM121) at the highest concentration of modulator tested (300 mM). BPAM344 (100 mM) also potentiated the peak current amplitude of KAR subunits GluK3a (59-fold), GluK2a (15- fold), GluK1b (5-fold), as well as the AMPA receptor subunit GluA1i (5-fold). X-ray structures of the three modulators in the GluK1 ligand-binding domain were determined, locating two modulator- binding sites at the GluK1 dimer interface. In conclusion, this study may enable the design of new positive allosteric modulators selective for KARs, which will be of great interest for further investigation of the function of KARs in vivo and may prove useful for pharmacologically controlling the activity of neuronal networks. [less ▲]Detailed reference viewed: 8 (0 ULg) Histoire du thymus : d'un organe vestigial à la programmation de la tolérance immunitaireGeenen, Vincent in Medecine Sciences : M/S (2017), 33(6-7), 634-644This synthesis presents the most important disruptions of conceptions about the thymus since its discovery in Antique Greece. For centuries, the thymus has been considered as a vestigial organ, and its ... [more ▼]This synthesis presents the most important disruptions of conceptions about the thymus since its discovery in Antique Greece. For centuries, the thymus has been considered as a vestigial organ, and its role in T-lymphocyte differentiation has been proposed only in the 1960’s. Most recent studies attribute to the thymus an essential and unique role in the programming of central immunological self-tolerance. The basal mechanism implicated in this function is the transcription in thymic epithelium of genes encoding precursors of self-antigens. Processing of these latters leads to presentation of self-antigens by the major histocompatibility complex (MHC) machinery expressed by thymic epithelial and dendritic cells. During fetal life, this presentation drives negative selection of T-cell clones harboring receptors with high affinity for these complexes MHC/self-antigen. After birth, this presentation promotes the generation of regulatory T cells specific for these complexes. A number of studies, as well as the identification of Aire and Fezf2 genes, have shown that a thymus dysfunction plays a crucial role in the development of organ-specific autoimmunity. [less ▲]Detailed reference viewed: 53 (1 ULg) Accounting for Price Endogeneity in Airline Itinerary Choice Models: An Application to Continental U.S. MarketsLurkin, Virginie ; Garrow, Laurie; Higgins, Matthew et alin Transportation Research. Part A : Policy & Practice (2017), 100Network planning models, which forecast the profitability of airline schedules, support many critical decisions, including equipment purchase decisions. Network planning models include an itinerary choice ... [more ▼]Network planning models, which forecast the profitability of airline schedules, support many critical decisions, including equipment purchase decisions. Network planning models include an itinerary choice model which is used to allocate air total demand in a city pair to different itineraries. Multinomial logit (MNL) models are commonly used in practice and capture how individuals make trade-offs among different itinerary attributes; however, none that we are aware of account for price endogeneity. This study formulates an itinerary choice model that is consistent with those used by industry and corrects for price endogeneity using a control function that uses several types of instrumental variables. We estimate our models using database of more than 3 million tickets provided by the Airlines Reporting Corporation. Results based on Continental U.S. markets for May 2013 departures show that models that fail to account for price endogeneity overestimate customers’ value of time and result in biased price estimates and incorrect pricing recommendations. The size and comprehensiveness of our database allows us to estimate highly refined departure time of day preference curves that account for distance, direction of travel, the number of time zones traversed, departure day of week and itinerary type (outbound, inbound or one-way). These time of day preference curves can be used by airlines, researchers, and government organizations in the evaluation of different policies such as congestion pricing. [less ▲]Detailed reference viewed: 47 (11 ULg) Actualités dans le traitement des tendinopathiesSauvant, Céline; Kaux, Jean-François in Journal de Traumatologie du Sport (2017), 34(2), 99-107Tendon injuries caused by overuse have been described as “tendinitis” for years before it was demonstrated that the histopathological process wasnot due to intratendinous inflammation. Cook and Purdam ... [more ▼]Tendon injuries caused by overuse have been described as “tendinitis” for years before it was demonstrated that the histopathological process wasnot due to intratendinous inflammation. Cook and Purdam proposed a continuum model of tendon pathology, which provides a better understandingof the condition and the possibility to adapt the treatment. This allows a better recovery and a lower recurrence rate of the tendinopathy. This articleis a review of current treatments used in clinical practice. [less ▲]Detailed reference viewed: 74 (4 ULg) Trop beau pour être vrai ? Quand un effet largement positif n’est pas nécessairement conclusifHenrard, Gilles in Minerva: Tijdschrift Voor Evidence Based Medicine (2017)Detailed reference viewed: 12 (0 ULg) Traumatologie des sports olympiques de ballon en salle. Partie 1: le basket-ballKaux, Jean-François ; Roberjot, Mathieu; DELVAUX, François et alin Journal de Traumatologie du Sport (2017), 34(2), 108-113Basketball, handball and volleyball are three indoor ball sports played in the Olympic Games. An important solicitation of the upper limbs is acommon characteristic of these three sports. The main ... [more ▼]Basketball, handball and volleyball are three indoor ball sports played in the Olympic Games. An important solicitation of the upper limbs is acommon characteristic of these three sports. The main objective of this review of the literature is to analyze the types of injury occurring in thesethree indoor ball games, looking for the specific localizations and their potential causes. Each sport will be discussed in a specific publication.Basketball is a very popular sport with a growing number of participants. The intensity of the game has increased as it has become more physical,leading to an increasing number of injuries. Ankle sprain is the most common injury in basketball. Back pain, finger fracture and tendon injury(jumper’s knee) or knee injury (anterior cruciate ligament tears) are also common. The main mechanism of traumatic injury is direct contact withthe opponent (during games) but there is also an increasing number of over-solicitation injuries. The length of time players must avoid sportsactivities after injury depends on the type of injury involved. [less ▲]Detailed reference viewed: 53 (4 ULg) Sartre, hériter de Heidegger ? Quelques remarques à propos du circuit de l'ipséité dans "L'Être et le Néant" [titre provisoire]Recchia, Fabio in Revista Ética e Filosofia Política (2017), 1Il n’est en philosophie d’héritage que gagné. Et en m’installant dans cette ambigüité propre au savoir philosophique, j’examine, dans ce texte, un développement peu étudié de la pensée sartrienne : sa ... [more ▼]Il n’est en philosophie d’héritage que gagné. Et en m’installant dans cette ambigüité propre au savoir philosophique, j’examine, dans ce texte, un développement peu étudié de la pensée sartrienne : sa théorie du « circuit de l’ipséité » de la conscience. Quant à mon objectif, il s’agira de faire le point sur le processus de maturation intellectuelle à l’issue duquel Sartre conçut l’ipséité comme un circuit. Ainsi je mets en évidence que certaines des réflexions de Heidegger, Bergson et Mauss, sur la notion d’identité personnelle ont constitué les héritages philosophiques mobilisés et transformés par la théorie sartrienne de l’ipséité. [less ▲]Detailed reference viewed: 48 (11 ULg) Insect fatty acids: A comparison of lipids from three Orthopterans and Tenebrio molitor L. larvaePaul, Aman ; Frederich, Michel ; Caparros Megido, Rudy et alin Journal of Asia-Pacific Entomology (2017), 20(2), 337-340In order to explore some potential insect sources of food lipids, the lipid compositions of three Orthopterans (Acheta domesticus, Conocephalus discolor and Chorthippus parallelus) were analyzed and ... [more ▼]In order to explore some potential insect sources of food lipids, the lipid compositions of three Orthopterans (Acheta domesticus, Conocephalus discolor and Chorthippus parallelus) were analyzed and compared with those of Tenebrio molitor larvae. A. domesticus, Co. discolor, Ch. parallelus and T. molitor larvae were found to contain approximately 15%, 13%, 10% and 32% lipids on dry weight, respectively. The lipids from three Orthopterans contain much higher amounts of essential fatty acids than those of T. molitor larvae. The two Orthopterans of the suborder Ensifera i.e., A. domesticus and Co. discolor contain linoleic acid in major quantities, while Ch. parallelus of the suborder Caelifera, contain α-linolenic acid in major quantities. The consumption of linoleic and α-linolenic fatty acid is linked with numerous health promoting effects. The factors that contribute to differences in fatty acid profiles of these insects are being discussed. At last the nutritional parameters including polyunsaturated to saturated and omega 6 to omega 3 fatty acid ratios of these insect lipids are also being discussed to understand the potential role of these lipids in human nutrition. [less ▲]Detailed reference viewed: 91 (15 ULg) LE CONTRÔLE DES NORMES RELATIVES À LA MODÉRATION DES RÉMUNÉRATIONS AU REGARD DU DROIT DE NÉGOCIATION COLLECTIVEClesse, Jacques ; Kéfer, Fabienne in Revue de Droit Social = Tijdschrift voor Sociaal Recht (2017), (1-2), 89-112En moins d’une semaine, deux lois ayant un impact important sur le montant des salaires sont entrées en vigueur. La loi du 23 avril 2015 concernant la promotion de l’emploi impose un saut d’index. La loi ... [more ▼]En moins d’une semaine, deux lois ayant un impact important sur le montant des salaires sont entrées en vigueur. La loi du 23 avril 2015 concernant la promotion de l’emploi impose un saut d’index. La loi du 28 avril 2015 établit la marge maximale pour l’évolution du coût salarial pour les années 2015 et 2016. Ces deux lois ont provoqué une forte opposition de la part des organisations syndicales. Traditionnellement, en Belgique, la formation des salaires relève de l’autonomie des partenaires sociaux. Par la voie des conventions collectives de travail, ceux-ci établissent le montant minimum des rémunérations au niveau du pays et des secteurs d’activité. Les organisations syndicales ont vu dans ces deux lois une atteinte grave portée par l’État à la concertation sociale. Après une première partie décrivant, sans pouvoir être exhaustive, les mécanismes de modération des salaires utilisés en Belgique depuis 1976, la contribution a pour objet d’examiner la régularité juridique de ces deux lois en regard du droit de négociation collective. Ce droit, qui constitue l’un des fondements juridiques du dialogue social et de l’action syndicale, appartient au catalogue des droits fondamentaux puisqu’il a été reconnu par différents instruments internationaux ainsi que par la Constitution de la Belgique. [less ▲]Detailed reference viewed: 43 (0 ULg) Magnetic Shielding Above 1 T at 20 K With Bulk, Large Grain YBCO Tubes Made by Buffer-aided Top Seeded Melt GrowthWera, Laurent ; Fagnard, Jean-François ; Kumar, Numbury Devendra et alin IEEE Transactions on Applied Superconductivity (2017), 27(4), YBCO tubes of ~ 10 mm diameter closed at one extremity were engineered by a Buffer-Aided Top Seeded Melt Growth fabrication process (BA-TSMG). These tubes can act as efficient “dc” magnetic shields and ... [more ▼]YBCO tubes of ~ 10 mm diameter closed at one extremity were engineered by a Buffer-Aided Top Seeded Melt Growth fabrication process (BA-TSMG). These tubes can act as efficient “dc” magnetic shields and are observed to reduce axial flux densities of 1.5 T by a factor of 100 at 20 K. Such performances are comparable in magnitude to the record threshold inductions reported for bulk MgB2 and Bi-2212 materials at lower temperatures. Magnetic shielding measurements for open and closed tubes at 77 K also show that the presence of the cap improves substantially the shielding performance at the closed extremity since it reduces the penetration through the open end. This fabrication technique is extremely promising for shielding “dc” stray fields generated by HTS magnets operated in a temperature range obtained by cryocoolers, liquid hydrogen (20 K) or liquid neon (27 K). [less ▲]Detailed reference viewed: 47 (17 ULg) The role of market-oriented institutions in the deployment of renewable energies: evidences from EuropeJacqmin, Julien in Applied Economics (2017)Focusing on European countries, this article investigates the link between market-oriented institutions, as measured by the Economic Freedom Index, and the production of energy from renewable sources. A ... [more ▼]Focusing on European countries, this article investigates the link between market-oriented institutions, as measured by the Economic Freedom Index, and the production of energy from renewable sources. A dynamic panel approach shows that this correlation is positive and significant while the subcomponents of the Economic Freedom Index reveal that not all market-oriented institutions have a similar impact. Indeed, long-term price stability and freedom to trade boost the reliance on renewable energies whereas the importance given to markets rather than governments has no significant impact. [less ▲]Detailed reference viewed: 19 (3 ULg) Pour un droit fondamental au logement : émergence et nuancesQuintart, Aurélie in Revue Générale de Droit Civil Belge = Tijdschrift voor Belgisch Burgerlijk (2017)The fundamental right to housing is written in article 23 of our Constitution along with others social and economical rights since 1994. It is said to be a necessary component for the right to respect for ... [more ▼]The fundamental right to housing is written in article 23 of our Constitution along with others social and economical rights since 1994. It is said to be a necessary component for the right to respect for human dignity. For the last decades, the right to housing has been quoted in many international declarations and conventions. However we still wonder: what is the real impact of this right to housing? How effective can it be? What interpretation can we give to case-law in this regard? We would like to bring some ideas and answer to the debate. Our article analyses the right to housing nowadays, as emerging out of treaties, laws and the international and national case-law. [less ▲]Detailed reference viewed: 15 (4 ULg) Esfera pública discursiva, nº2Becerra Mayor, David in Esfera pública discursiva (2017), 2Número 2 de "Esfera pública discursiva", revista de crítica e información literaria realizada por los estudiantes de "Stylistique et critique de l'espagnol moderne" de la Université de LiègeDetailed reference viewed: 22 (0 ULg) Morphology of the UV aurorae Jupiter during Juno’s first perijove observationsBonfond, Bertrand ; Gladstone, G. R.; Grodent, Denis et alin Geophysical Research Letters (2017)On 27 August 2016, the NASA Juno spacecraft performed its first close-up observations of Jupiter during its perijove. Here we present the UV images and color ratio maps from the Juno-ultraviolet ... [more ▼]On 27 August 2016, the NASA Juno spacecraft performed its first close-up observations of Jupiter during its perijove. Here we present the UV images and color ratio maps from the Juno-ultraviolet spectrometer UV imaging spectrograph acquired at that time. Data were acquired during four sequences (three in the north, one in the south) from 5:00 UT to 13:00 UT. From these observations, we produced complete maps of the Jovian aurorae, including the nightside. The sequence shows the development of intense outer emission outside the main oval, first in a localized region (255 ∘ –295 ∘ System III longitude) and then all around the pole, followed by a large nightside protrusion of auroral emissions from the main emission into the polar region. Some localized features show signs of differential drift with energy, typical of plasma injections in the middle magnetosphere. Finally, the color-ratio map in the north shows a well-defined area in the polar region possibly linked to the polar cap. [less ▲]Detailed reference viewed: 31 (6 ULg) Is the arbitrary symmetrical?Badir, Sémir in Semiotica (2017)Arbitrariness is commonly seen as a major concept in Saussure’s thought, and it even receives the status of a “principle” in his theory. It is not only the characteristic feature of the relation between ... [more ▼]Arbitrariness is commonly seen as a major concept in Saussure’s thought, and it even receives the status of a “principle” in his theory. It is not only the characteristic feature of the relation between the signifier and the signified (the semiological relation is arbitrary), but moreover it is constitutive of this very relation (the relation is semiological because it is arbitrary; there is a so-called “semiological relation” established between a signifier and a signified because of the principle of arbitrariness). And when linguists and other Saussurean interpreters comment on the concept of arbitrariness, they usually imply a binary relation: the semiological relation is arbitrary due to the fact that the signifier is arbitrarily chosen vis-à-vis the signified, and vice versa. I will be questioning the latter assertion in this paper. In my opinion, the symmetry of the semiological relation has not been properly demonstrated. The signifier can be seen as arbitrary with regard to the signified, but no reason has been provided to recognize the converse. Instead a number of arguments can be put forth to see arbitrariness as a concept that implies a non-symmetrical relation. [less ▲]Detailed reference viewed: 17 (1 ULg) D. W. Vasaco and A. Datta-Gupta: Subsurface Fluid Flow and Imaging—With Applications for Hydrology, Reservoir Engineering and GeophysicsDassargues, Alain in Mathematical Geosciences (2017)Book reviewDetailed reference viewed: 27 (1 ULg) Effects of preference and sensory modality on behavioral reaction in patients with disorders of consciousnessHeine, Lizette ; Tillmann, Barbara; Hauet, Marjolaine et alin Brain Injury (2017)Background: Reliable evaluation of patients with unresponsive wakefulness syndrome (UWS) or in a minimally conscious state (MCS) remains a major challenge. It has been suggested that the expression of ... [more ▼]Background: Reliable evaluation of patients with unresponsive wakefulness syndrome (UWS) or in a minimally conscious state (MCS) remains a major challenge. It has been suggested that the expression of residual cerebral function could be improved by allowing patients to listen to their favourite music. However, the potential effect of music on behavioural responsiveness, as well as the effect of preferred stimuli in other sensory modalities (e.g. olfaction), remain poorly understood. Objective: The aim of our study was to investigate the effect of sensory modality (auditory versus olfactory) and preference (preferred versus neutral) of the test stimuli on patients’ subsequent performance on the Coma Recovery Scale-Revised (CRS-R). Research design: Within-subject design because of inter-individual differences between patients. Methods and procedures: We studied four items from the CRS-R (visual pursuit using a mirror, auditory localization of the own name and two movements to command) in 13 patients (7 MCS; 6 UWS). Main outcomes and results: Auditory stimuli triggered higher responsiveness compared to olfactory stimuli, and preferred stimuli were followed by higher scores than did neutral stimuli. Conclusions: Findings suggest that preferred auditory stimuli at the bedside contribute to the expression of residual function and could improve the diagnostic assessment. [less ▲]Detailed reference viewed: 21 (5 ULg) Controlled synthesis of fluorinated copolymers via cobalt-mediated radical copolymerization of perfluorohexylethylene and vinyl acetateDemarteau, Jérémy ; Améduri, Bruno; Ladmiral, Vincent et alin Macromolecules (2017), 50(10), 3750-3760Designing novel polyfluoropolymer architectures is attractive for the development of new applications, such as advanced coatings, purification membranes, or materials for energy. Nevertheless, controlling ... [more ▼]Designing novel polyfluoropolymer architectures is attractive for the development of new applications, such as advanced coatings, purification membranes, or materials for energy. Nevertheless, controlling the radical polymerization of fluoroalkenes is very challenging due to the high reactivity of the propagating fluorinated macroradicals. This study aims at exploring the controlled copolymerization of perfluoro- hexylethylene (PFHE) and vinyl acetate (VAc) in order to prepare a range of well-defined statistical poly(PFHE-stat-VAc) copolymers with different compositions. Cobalt-mediated radical polymerization demonstrated to be active at 40 °C starting from an alkylcobalt(III) initiator, and copolymers with a fluorinated monomer content as high as ca. 80 wt % were successfully prepared. Reactivity ratios were determined to be rVAc = 0.18 and rPFHE = 0 at 40 °C and emphasized a clear tendency for alternation. Unprecedented PFHE/VAc containing block copolymers were also prepared via a single-step approach or through sequential copolymerizations. Finally, hydrolysis of the pendant ester groups of these copolymers led to the corresponding fluorinated copolymers bearing vinyl alcohol (VOH). A preliminary solution behavior study, carried out by dynamic light scattering and transmission electron microscopy on block copolymers composed of PFHE and VAc or VOH units, evidenced a marked amphiphilicity of the copolymer composed of an extremely hydrophobic PFHE block associated with a highly hydrophilic PVOH segment. [less ▲]Detailed reference viewed: 27 (6 ULg) Puzzling Out Synaptic Vesicle 2 Family Members FunctionsBartholomé, Odile ; Van Den Ackerveken, Priscilla ; Sanchez Gil, Judit et alin Frontiers in Molecular Neuroscience (2017)Detailed reference viewed: 2 (0 ULg) Healing Effect of Controlled Anti-Electromigration on Conventional and High-Tc Superconducting NanowiresBaumans, Xavier ; Lombardo, Joseph ; Brisbois, Jérémy et alin Small : Nano Micro (2017), 1700384The electromigration process has the potential capability to move atoms one by one when properly controlled. It is therefore an appealing tool to tune the cross section of monoatomic compounds with ... [more ▼]The electromigration process has the potential capability to move atoms one by one when properly controlled. It is therefore an appealing tool to tune the cross section of monoatomic compounds with ultimate resolution or, in the case of polyatomic compounds, to change the stoichiometry with the same atomic precision. As demonstrated here, a combination of electromigration and anti-electromigration can be used to reversibly displace atoms with a high degree of control. This enables a fine adjustment of the superconducting properties of Al weak links, whereas in Nb the diffusion of atoms leads to a more irreversible process. In a superconductor with a complex unit cell (La 2−x Ce x CuO 4 ), the electromigration process acts selectively on the oxygen atoms with no apparent modification of the structure. This allows to adjust the doping of this compound and switch from a superconducting to an insulating state in a nearly reversible fashion. In addition, the conditions needed to replace feedback controlled electromigration by a simpler technique of electropulsing are discussed. These findings have a direct practical application as a method to explore the dependence of the characteristic parameters on the exact oxygen content and pave the way for a reversible control of local properties of nanowires. [less ▲]Detailed reference viewed: 7 (2 ULg) Defining thermal comfort boundaries for heating and cooling demand estimation in Iran's urban settlementsRoshan, GhR.; Farrokhzad, M.; Attia, Shady in Building & Environment (2017), 121Iran has diverse climate variability, comfort boundaries for each geographic region must be defined in order to present current architectural design recommendations and proper mechanical systems design to ... [more ▼]Iran has diverse climate variability, comfort boundaries for each geographic region must be defined in order to present current architectural design recommendations and proper mechanical systems design to meet building's heating and cooling energy demand. Therefore, two components of the temperature and relative humidity of 148 stations with the longest common statistical period of twenty years (1994–2014), which have been in daily scale were selected to calibrate and redefine the thermal boundary conditions in Iran. Givoni chart was used to define and visualize the bioclimatic conditions in buildings. The results of this study indicate that only 18% of the 148 stations days, falls in the thermal comfort bioclimatic conditions. After calibration of the base comfort temperature, we found that the upper threshold of this component varies from at least 22.62 °C for Ardebil to 25.94 °C for Dorudzan station and the low threshold of this component belongs to Ardebil with at least 20.13 °C up to its maximum value with 22 °C which belongs to Dorudzan. Spatial distribution of cooling and heating days show that their maximum threshold has been for cores in Northeastern half of Iran, Iran's Western half and some Central parts of Iran and the minimum threshold of these two components belongs to the beaches of north and south of the country. The findings present updated thermal comfort boundaries that can be used by architects, engineers and policy makers to achieve, in turn, more energy efficient homes and high quality indoor and outdoor living environments. [less ▲]Detailed reference viewed: 43 (4 ULg) First Characterisation of Volatile Organic Compounds Emitted by Banana PlantsBerhal, Chadi ; De Clerck, Caroline ; Fauconnier, Marie-Laure et alin Scientific Reports (2017)Banana (Musa sp.) ranks fourth in term of worldwide fruit production, and has economical and nutritional key values. The Cavendish cultivars correspond to more than 90% of the production of dessert banana ... [more ▼]Banana (Musa sp.) ranks fourth in term of worldwide fruit production, and has economical and nutritional key values. The Cavendish cultivars correspond to more than 90% of the production of dessert banana while cooking cultivars are widely consumed locally around the banana belt production area. Many plants, if not all, produce Volatile Organic Compounds (VOCs) as a means of communication with their environment. Although flower and fruit VOCs have been studied for banana, the VOCs produced by the plant have never been identified despite their importance in plant health and development. A volatile collection methodology was optimized to improve the sensitivity and reproducibility of VOCs analysis from banana plants. We have identified 11 VOCs for the Cavendish, mainly (E,E)-α-farnesene (87.90 ± 11.28 ng/μl), methyl salicylate (33.82 ± 14.29) and 6-methyl-5-hepten-2-one (29.60 ± 11.66), and 14 VOCs for the Pacific Plantain cultivar, mainly (Z,E)-α-farnesene (799.64 ± 503.15), (E,E)-α-farnesene (571.24 ± 381.70) and (E) β ocimene (241.76 ± 158.49). This exploratory study paves the way for an in-depth characterisation of VOCs emitted by Musa plants. [less ▲]Detailed reference viewed: 33 (3 ULg) Effects of isolated versus combined learning enactments in an online courseVerpoorten, Dominique ; Westera, Wim; Specht, Marcusin International Journal of Technology Enhanced Learning (2017), 9(2), 169-185In a controlled experiment on the effects of frequent and local digital annotations, 137 volunteers covered an online course under three possible conditions: no/free/question-based digital annotations ... [more ▼]In a controlled experiment on the effects of frequent and local digital annotations, 137 volunteers covered an online course under three possible conditions: no/free/question-based digital annotations. Results show no difference in performance between groups when annotation behaviour is considered in isolation. However, analyses conducted within treatments provide indications of a positive impact on performance when annotation rates are taken into consideration, and coupled with other enactments tracked in the course. Combined in engagement profiles (Learning DNAs), these enactments suggest that what makes active learning efficient might be an ongoing crisscrossing between a firstorder learning activity (the study of the course) and a series of second order activities, such as making notes. Students who manage to coordinate these activities at a higher rate perform better. This observation opens a line of reasoning about what determines the quality of a mental engagement in a learning task, in terms of balance and rotation of cognitive and metacognitive operations. [less ▲]Detailed reference viewed: 49 (14 ULg) Recours aux Sources: Parcours d'un alumniSow, Aboubakry in 15e Jour du Mois (Le) mai 2017 n° 2064 (2017) Risk Assessment of Florists Exposed to Pesticide Residues through Handling of Flowers and Preparing BouquetsToumi, Khaoula ; Laure, Joly; Vleminckx, Christiane et alin International Journal of Environmental Research and Public Health (2017), 14(5)Abstract: Flowers are frequently treated with pesticides and, as a result, florists handling daily a large number of flowers can be exposed to pesticide residues. A study was conducted among twenty ... [more ▼]Abstract: Flowers are frequently treated with pesticides and, as a result, florists handling daily a large number of flowers can be exposed to pesticide residues. A study was conducted among twenty volunteer florists located in Namur Province and in the Brussels Capital Region of Belgium in order to assess their potential dermal exposure to dislodgeable pesticide residues transferred from flowers to hands. Two pairs of cotton gloves were worn during two consecutive half days while handling flowers and preparing bouquets (from min 2 h to max 3 h/day). The residual pesticide deposits on the glove samples were extracted with a multi-residue Quick Easy Cheap Effective Rugged Safe (QuEChERS) method and analyzed by a combination of gas and liquid chromatography tandem mass spectrometry (GC-MS/MS and LC-MS/MS) by an accredited laboratory. A total of 111 active substances (mainly insecticides and fungicides) were detected, with an average of 37 active substances per sample and a total concentration per glove sample of 22.22 mg/kg. Several predictive levels of contamination were considered to assess the risk. The potential dermal exposures (PDE) of florists were estimated at the average, for different percentiles, and at the maximum concentration of residues in samples. At the PDE P90 and at the PDEMAX (or worst case) values, three and five active substances respectively exceed the Acceptable Operator Exposure Level (AOEL), indicating risk situations. For the systemic exposure (SE), one active substance (clofentezine) exceeds the AOEL at the P90 predictive level. In the worst case, SEMAX (at the maximum concentrations), four active substances (clofentezine, famoxadone, methiocarb, and pyridaben) exceed their respective AOEL values. Among the 14 most frequently detected active substances, two have SEMAX values exceeding the AOEL. Exposure could be particularly critical for clofentezine with an SEMAX value four times higher than the AOEL (393%). The exposure of florists appeared to be an example of a unique professional situation in which workers are exposed regularly to both a very high number of toxic chemicals and rather high concentration levels. Therefore the priority should be to raise the level of awareness among the florists who must change their habits and practices if they want to minimize their exposure. [less ▲]Detailed reference viewed: 24 (2 ULg) Comparative Feeding Ecology of Cardinalfishes (Apogonidae) at Toliara Reef, MadagascarFrederich, Bruno ; Michel, Loïc ; Zaeytydt, Esther et alin Zoological Studies (2017), 56(10), 1-14Despite their importance in coral reef ecosystem function and trophodynamics, the trophic ecology of nocturnal fishes (e.g. Apogonidae, Holocentridae, Pempheridae) is by far less studied than diurnal ones ... [more ▼]Despite their importance in coral reef ecosystem function and trophodynamics, the trophic ecology of nocturnal fishes (e.g. Apogonidae, Holocentridae, Pempheridae) is by far less studied than diurnal ones. The Apogonidae (cardinalfishes) include mostly carnivorous species and evidence of trophic niche partitioning among sympatric cardinalfishes is still limited. The present study combines stomach contents and stable isotope analyses to investigate the feeding ecology of an assemblage of eight cardinalfishes from the Great Reef of Toliara (SW Madagascar). δ13C and δ15N of fishes ranged between -17.49‰ and -10.03‰ and between 6.28‰ and 10.74‰, respectively. Both stomach contents and stable isotopes showed that they feed on planktonic and benthic animal prey in various proportions. Previous studies were able to group apogonids in different trophic categories but such a discrimination is not obvious here. Large intra-specific variation in the stomach contents and temporal variation in the relative contribution of prey to diet support that all apogonids should be considered as generalist, carnivorous fishes. However the exploration of the isotopic space revealed a clear segregation of isotopic niches among species, suggesting a high level of resource partitioning within the assemblage. According to low inter-specific variation in stomach content compositions, we argue that the differences in isotopic niches could be driven by variation in foraging locations (i.e. microhabitat segregation) and physiology among species. Our temporal datasets demonstrate that the trophic niche partitioning among cardinalfishes and the breadth of their isotopic niches are dynamic and change across time. Factors driving this temporal variation need to be investigated in further studies. [less ▲]Detailed reference viewed: 44 (3 ULg) Recovering unlawful advantages in the context of EU State aid tax ruling investigationsVan Cleynenbreugel, Pieter in Market and Competition Law Review (2017), 1(1), 15-48The European Commission has recently begun to focus increasingly on the compatibility of Member States’ tax ruling procedures with EU State aid law. In that respect, it has ordered the recovery of ... [more ▼]The European Commission has recently begun to focus increasingly on the compatibility of Member States’ tax ruling procedures with EU State aid law. In that respect, it has ordered the recovery of unlawfully granted advantages through those procedures. This article examines to what extent the application of EU law principles of legitimate expectations and legal certainty are to take stock in State aid recovery proceedings of this particular legal certainty-enhancing and legitimate expectationscreating tax ruling context. It additionally questions whether recovery in this particular context should be tailored to the specific national ruling framework having resulted in the advantage granted in violation of Article 107 TFEU [less ▲]Detailed reference viewed: 9 (0 ULg) How does policy learning occur? The case of Belgian mental health care reformsThunus, Sophie ; Schoenaers, Frédéric in Policy and Society (2017)This article asks how policy learning is achieved and whether and how it impacts on policy change. By drawing on the empirical case of Belgian mental health reforms, it shows that policy learning occurs ... [more ▼]This article asks how policy learning is achieved and whether and how it impacts on policy change. By drawing on the empirical case of Belgian mental health reforms, it shows that policy learning occurs through the very practice of policy-making. In-depth analyses of the process of preparing and devising, a current reform of mental health care delivery, called Reform 107, evidence that the transformation of policy learning – through verbal expression, inscription in documents or enactment in social situations such as meetings – is crucial to its impact on policy change. A phenomenological approach to knowledge in policy helps to perceive and describe the transformation of policy learning through practical actions and interactions involved in devising policy change. Analytically, looking at this transformation entails shifting the focus from big and visible changes in policy objectives and instruments to micro policy practices such as meeting and writing documents. Placing the focus on micro policy practices should not lead, however, to a disregard for the social context in which they develop. The interactionist concept of linked ecologies provides the means to consider social regulations influencing policy learning without underestimating their very ephemeral and contingent nature [less ▲]Detailed reference viewed: 45 (7 ULg) Dynamic of soil drying close to saturation: What can we learn from a comparison between X-ray computed microtomography and the evaporation method?Parvin, Nargish ; Beckers, Eléonore ; Plougonven, Erwan et alin Geoderma (2017), 302The soil water retention curve (SWRC) is a unique relationship between water content and soil water potential. SWRC in near saturation gives the dimension of soil macroporosity which plays an important ... [more ▼]The soil water retention curve (SWRC) is a unique relationship between water content and soil water potential. SWRC in near saturation gives the dimension of soil macroporosity which plays an important role in water translocation into soil. Thus, the accurate measurement of SWRC is crucial. The aim of this study is to compare SWRC obtained through two different methods: X-ray computed microtomography (X-ray CT) and evaporation method by HYPROP device. Three different depths (0–10, 25–30 and 45–60 cm) are considered for soil sampling. The results showed significant differences in SWRC between the techniques. The SWRC from X-ray CT showed more volumetric water content at 25–30 cm (0.044) and 45–60 cm (0.024) than evaporation at saturation (0 kPa) in cases where the macroporosity was higher. Macropores may have connections with neighbouring pores of smaller sizes. Hence we assume that these pores can be observed through X-ray CT but cannot be evaluated by evaporation. As macropores with narrow opening do not evaporate at very low tension. These pores therefore got empty at relatively higher tension. Consequently, SWRC near saturation appeared rather flatter with the evaporation method where the X-ray CT presented deviation. Accordingly, interpretation of macro pores from SWRC through evaporation method would give comparatively smaller volume of macropores than they really are. Pore morphology and other hydraulic functions of soil, for example, mean connection surface of pores, hydraulic conductivity, and the efficiency of water conducting macropores also support the X-ray CT findings. [less ▲]Detailed reference viewed: 20 (6 ULg) Adipsic diabetes insipidus revealing a bifocal intracranial germinomaKREUTZ, Julie ; Potorac, Iulia ; LUTTERI, Laurence et alin Annales d'Endocrinologie (2017)Abstract Adipsic diabetes insipidus is a rare complication of intracranial tumors in which impaired antidiuretic hormone secretion is associated with the loss of thirst sensation. Here, we present the ... [more ▼]Abstract Adipsic diabetes insipidus is a rare complication of intracranial tumors in which impaired antidiuretic hormone secretion is associated with the loss of thirst sensation. Here, we present the case of a patient with bifocal intracranial germinoma, diagnosed due to symptoms mainly caused by adipsic diabetes insipidus. This is, to our knowledge, the first case of adipsic diabetes insipidus revealing an intracranial germinoma reported in the literature. We describe the diagnostic procedures and the three-year follow-up of this patient. Management of intracranial germ-cell tumors is made complex by the wide range of histological features. Although germinomas have a generally better prognosis than most nongerminomatous tumors, they can have severe or even life-threatening presentations. Adipsic diabetes insipidus is one such severe presentation and its rarity can make it difficult to recognize and manage. Awareness of this potential entity is therefore important for clinical practice. Le diabète insipide adipsique est une des rares complications des tumeurs intracrâniennes. Il associe une baisse de la sécrétion d’hormone antidiurétique à une perte de la sensation de soif et ilsignale souvent la présence d’une lésion qui atteint ou envahit l’hypothalamus. Nous présentons le cas d’une patiente avec un germinome intracrânien bifocal diagnostiqué devant un tableau de diabète insipide adipsique. À notre connaissance, il s’agit du premier cas de la littérature d’un diabète insipide révélant un germinome intracrânien. La prise en charge des tumeurs germinales intracrâniennes est complexe du fait des phénotypes histologiques divers. Bien que les germinomes ont généralement un meilleur pronostic que les tumeurs non-germinomateuses, ils peuvent avoir des présentations sévères. Le diabète insipide adipsique est une de ces présentations sévères et sa rareté peut rendre son diagnostic et sa prise en charge difficiles. La reconnaissance de cette entité potentielle est, dès lors, importante pour la pratique clinique [less ▲]Detailed reference viewed: 26 (6 ULg) AIP mutations and gigantismRostomyan, Liliya ; Potorac, Iulia ; BECKERS, Pablo et alin Annales d'Endocrinologie (2017)AIP mutations are rare in sporadic acromegaly but they are seen at a higher frequency among certain specific populations of pituitary adenoma patients (pituitary gigantism cases, familial isolated ... [more ▼]AIP mutations are rare in sporadic acromegaly but they are seen at a higher frequency among certain specific populations of pituitary adenoma patients (pituitary gigantism cases, familial isolated pituitary adenoma (FIPA) kindreds, and patients with macroadenomas who are diagnosed ≤ 30 years). AIP mutations are most prevalent in patients with pituitary gigantism (29% of this group were found to have mutations in AIP gene). These data support targeted genetic screening for AIP mutations/deletions in these groups of pituitary adenoma patients. Earlier diagnosis of AIP-related acromegaly-gigantism cases enables timely clinical evaluation and treatment, thereby improving outcomes in terms of excessive linear growth and acromegaly comorbidities. Bien que les mutations du gène AIP soient rares dans les cas d’acromégalie sporadique, l’importance de ces mutations est établie dans des populations spécifiques de patients telles que les patients qui souffrent de familial isolated pituitary adenomas (FIPA), de gigantisme ou qui présentent un macroadénome hypophysaire avant l’âge de 30 ans. C’est dans le gigantisme qu’elles sont le plus fréquemment retrouvées (29 % des géants présentent une mutation de ce gène). Dans ces populations, nos données suggèrent qu’il est utile de réaliser un screening ciblé pour les mutations ou délétions du gène AIP. La reconnaissance précoce des cas d’acromégalie et de gigantisme permet une évaluation clinique et un traitement appropriés de ces patients. Elle contribue à améliorer les résultats des traitements tant en terme de croissance excessive qu’en ce qui concerne les comorbidités liées à l’acromégalie. [less ▲]Detailed reference viewed: 29 (8 ULg) Spray droplet impaction outcomes for different plant species and spray formulationsMassinon, Mathieu ; De Cock, Nicolas ; Forster, W. Alison et alin Crop Protection (2017), 99A track-sprayer combined with a high-speed camera were used to visualize and identify droplet impaction outcomes for three formulations (water, 0.1% LI 700® (lecithin, a mixture of soya oils, propionic ... [more ▼]A track-sprayer combined with a high-speed camera were used to visualize and identify droplet impaction outcomes for three formulations (water, 0.1% LI 700® (lecithin, a mixture of soya oils, propionic acid and surfactants) in water and 0.1% Pulse® (non-ionic surfactant, trisiloxane ethoxylate) in water) on four plant species (bean (Vicia faba L.), avocado (Persea americana L.), barnyard grass (Echinochloa crus-galli L. P. Beauv.) and cabbage (Brassica oleracea L.)) selected to represent a wide range of leaf surface characters. Droplet sizes and velocities were measured by image analysis and a multiple hypothesis tracking algorithm. Impaction outcomes were categorized into adhesion, bounce, or shatter. The probability of each outcome was estimated from logistic regression models related to the dimensionless Weber number. This approach is in contrast to various deterministic threshold criteria for droplet bounce or shatter that have been used to model droplet impaction events on leaves. It also provides a simple visual and numerical presentation of the complexity of impaction processes, and the relative influence of leaf surface character versus formulation for droplets with different impaction energies. [less ▲]Detailed reference viewed: 29 (5 ULg)