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See detailIPCAPS: an R package for iterative pruning to capture population structure
Chaichoompu, Kridsadakorn ULg; Abegaz Yazew, Fentaw; Tongsima, Sissades et al

in Bioinformatics : Application Notes (in press)

Resolving population genetic structure is challenging, especially when dealing with closely related populations. Although Principal Component Analysis (PCA)-based methods and genomic var- iation with ... [more ▼]

Resolving population genetic structure is challenging, especially when dealing with closely related populations. Although Principal Component Analysis (PCA)-based methods and genomic var- iation with single nucleotide polymorphisms (SNPs) are widely used to describe shared genetic an- cestry, improvements can be made targeting fine-level population structure. This work presents an R package called IPCAPS, which uses SNP information for resolving possibly fine-level population structure. The IPCAPS routines are built on the iterative pruning Principal Component Analysis (ipP- CA) framework to systematically assign individuals to genetically similar subgroups. Our tool is able to detect and eliminate outliers in each iteration to avoid misclassification. It can be extended to de- tect subtle subgrouping in patients as well. In addition, IPCAPS supports different measurement scales for variables used to identify substructure. Hence, panels of gene expression and methylation data can be accommodated. [less ▲]

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See detailMulti-temporal monitoring of a regional riparian buffer network (>12,000 km) with LiDAR and photogrammetric point clouds
Michez, Adrien ULg; Piégay, Hervé; Lejeune, Philippe ULg et al

in Journal of Environmental Management (in press)

Riparian buffers are of major concern for land and water resource managers despite their relatively low spatial coverage. In Europe, this concern has been acknowledged by different environmental ... [more ▼]

Riparian buffers are of major concern for land and water resource managers despite their relatively low spatial coverage. In Europe, this concern has been acknowledged by different environmental directives which recommend multi-scale monitoring (from local to regional scales). Remote sensing methods could be a cost-effective alternative to field-based monitoring, to build replicable “wall-to-wall” monitoring strategies of large river networks and associated riparian buffers. The main goal of our study is to extract and analyze various parameters of the riparian buffers of up to 12,000 km of river in southern Belgium (Wallonia) from three-dimensional (3D) point clouds based on LiDAR and photogrammetric surveys to i) map riparian buffers parameters on different scales, ii) interpret the regional patterns of the riparian buffers and iii) propose new riparian buffer management indicators. We propose different strategies to synthesize and visualize relevant information at different spatial scales ranging from local (<10 km) to regional scale (>12,000 km). Our results showed that the selected parameters had a clear regional pattern. The reaches of Ardenne ecoregion have channels with the highest flow widths and shallowest depths. In contrast, the reaches of the Loam ecoregion have the narrowest and deepest flow channels. Regional variability in channel width and depth is used to locate management units potentially affected by human impact. Riparian forest of the Loam ecoregion is characterized by the lowest longitudinal continuity and mean tree height, underlining significant human disturbance. As the availability of 3D point clouds at the regional scale is constantly growing, our study proposes reproducible methods which can be integrated into regional monitoring by land managers. With LiDAR still being relatively expensive to acquire, the use of photogrammetric point clouds combined with LiDAR data is a cost-effective means to update the characterization of the riparian forest conditions. [less ▲]

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See detailRéduire l’altérité au travers des processus de traduction et de représentation
Leclercq, Bruno ULg; Smette, Bernard ULg

in Doctorales. Revue LLA-SHS de Montpellier (in press)

WVO Quine questions the « myth » of an ideal realm of shared meanings which every national language would express in its own way. Against the hope of transparent translations, he insists on the necessity ... [more ▼]

WVO Quine questions the « myth » of an ideal realm of shared meanings which every national language would express in its own way. Against the hope of transparent translations, he insists on the necessity for building equivalences from one language to another through a strategy of reducing the differences in rationality among nations as much as possible. According to Quine, otherness is not insuperable impediment to meeting/encounter and mutual understanding ; by throwing our conceptual schemes on the other communities’ uses/practices – which of course involves some symbolic violence – gaps can always been narrowed. Similarly E. Laclau questions the traditional conception of political representation, which is seen as the transparent process of transmitting someone’s will or interests on another level. For this ideal conception of representation, Laclau substitutes a pragmatic conception which takes in account the irreducible gap between the actors as well as the constitutive opacity of the process of representation : the subject’s will is constituted within the process of representation and through the representative’s productive role. In order to be transposed at the decision-making level, the subject’s interests must be translated by the representative as well as be negotiated with the other represented interests. This implies that the initial will undergoes some identity transformations. [less ▲]

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See detailLes Trois Trois Petits Cochons et le Grand Méchant Loup. La rencontre de deux archétypes
Jousten, Lison ULg

in La revue des lettres modernes (in press)

Image de la menace par excellence, le Grand Méchant Loup est un adversaire dont on ne compte plus les apparitions, notamment dans les fictions destinées au jeune public. Dans Les Trois Petits Cochons, qui ... [more ▼]

Image de la menace par excellence, le Grand Méchant Loup est un adversaire dont on ne compte plus les apparitions, notamment dans les fictions destinées au jeune public. Dans Les Trois Petits Cochons, qui s’impose comme cas d’école parmi ces récits où surgit l’animal redouté, le loup devient l’ennemi du cochon, une créature traditionnellement associée à l’enfance. Ce tandem, qui repose sur un principe général d’opposition, brasse avec lui une série de représentations qui transparaissent en filigrane. Le détour opéré par l’histoire culturelle du cochon et quelques-uns de ses prolongements cinématographiques permet de dessiner progressivement les contours de la place occupée par le loup dans ce conte. [less ▲]

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See detailLevallois et Gravettien
Otte, Marcel ULg; Noiret, Pierre ULg

in Praehistoria (in press)

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein ... [more ▼]

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein du Gravettien touchent autant les processus de symbolisation dans l’art et les sépultures. Elles affectent différents substrats eurasiatiques, plutôt septentrionaux, comme mis en réserve dès les Néandertaliens. [less ▲]

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See detailOn-sky performance of the QACITS pointing control technique with the Keck/NIRC2 vortex coronagraph
Huby, Elsa ULg; Bottom, Michael; Femenia, Bruno et al

in Astronomy and Astrophysics (in press)

A vortex coronagraph is now available for high contrast observations with the Keck/NIRC2 instrument at L band. Reaching the optimal performance of the coronagraph requires fine control of the wavefront ... [more ▼]

A vortex coronagraph is now available for high contrast observations with the Keck/NIRC2 instrument at L band. Reaching the optimal performance of the coronagraph requires fine control of the wavefront incident on the phase mask. In particular, centering errors can lead to significant stellar light leakage that degrades the contrast performance and prevents the observation of faint planetary companions around the observed stars. It is thus critical to correct for the possible slow drift of the star image from the phase mask center, generally due to mechanical flexures induced by temperature and/or gravity field variation, or to misalignment between the optics that rotate in pupil tracking mode. A control loop based on the QACITS algorithm for the vortex coronagraph has thus been developed and deployed for the Keck/NIRC2 instrument. This algorithm executes the entire observing sequence, including the calibration steps, initial centering of the star on the vortex center and stabilisation during the acquisition of science frames. On-sky data show that the QACITS control loop stabilizes the position of the star image down to 2.4 mas rms at a frequency of about 0.02 Hz. However, the accuracy of the estimator is probably limited by a systematic error due to a misalignment of the Lyot stop with respect to the entrance pupil, estimated to be on the order of 4.5 mas. A method to reduce the amplitude of this bias down to 1 mas is proposed. The QACITS control loop has been successfully implemented and provides a robust method to center and stabilize the star image on the vortex mask. In addition, QACITS ensures a repeatable pointing quality and significantly improves the observing efficiency compared to manual operations. It is now routinely used for vortex coronagraph observations at Keck/NIRC2, providing contrast and angular resolution capabilities suited for exoplanet and disk imaging. [less ▲]

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See detailContribution à un lexique épigraphique: "deltographéma"
Famerie, Etienne ULg

in Zeitschrift für Papyrologie und Epigraphik (in press)

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See detailLes troubles du sommeil chez l'enfant autiste, quel rôle pour le pédopsychiatre?
Abate Ekollo, Joëlle; Malchair, Alain ULg

in Acta Psychiatrica Belgica (in press)

Les troubles du sommeil sont fréquents chez l’enfant et leurs origines sont diverses. Ces troubles ont leur ancrage dans le développement neurophysiologique et psychoaffectif de l’enfant. Les enfants ... [more ▼]

Les troubles du sommeil sont fréquents chez l’enfant et leurs origines sont diverses. Ces troubles ont leur ancrage dans le développement neurophysiologique et psychoaffectif de l’enfant. Les enfants souffrant de troubles du spectre autistique présentent un déficit de sommeil, qui peut durer jusqu’à l’adolescence. Les troubles du spectre autistique comportent des comorbidités multiples, dont des altérations du sommeil. Ils sont importants à caractériser dans cette population, car ils peuvent avoir un impact négatif sur les comportements diurnes. Par ailleurs, ils entrainent souvent des difficultés au sein de la famille. La prise en charge doit avant tout prendre en compte le contexte environnemental afin d’améliorer les habitudes et l’hygiène du sommeil. Des questionnaires ainsi que des agendas de sommeil ont été remplis par des parents afin de démontrer l’importance d’une évaluation et d’une prise en compte des troubles du sommeil chez les enfants souffrant d’autisme en consultation pédopsychiatrique. [less ▲]

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See detailL'espace transitionnel winnicotien et l'_Urraum_ kantien
Seba, Jean-Renaud ULg

in Revista Natureza Humana (in press)

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See detailEntre mutation et métissage Co-construction d’une ethnographie émancipatrice et féministe
Vivas Romero, Maria ULg

in Émulation Revue des Jeunes Chercheuses et chercheurs en sciences sociales (in press)

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See detailA Quantitative Doignon-Bell-Scarf theorem
Aliev, Iskander; Bassett, Robert; De Loera, Jesus et al

in Combinatorica (in press)

The famous Doignon-Bell-Scarf theorem is a Helly-type result about the existence of integer solutions to systems of linear inequalities. The purpose of this paper is to present the following quantitative ... [more ▼]

The famous Doignon-Bell-Scarf theorem is a Helly-type result about the existence of integer solutions to systems of linear inequalities. The purpose of this paper is to present the following quantitative generalization: Given an integer k, we prove that there exists a constant c(n,k), depending only on the dimension n and on the number k, such that if a bounded polyhedron {x in R^n : Ax <= b} contains exactly k integer points, then there exists a subset of the rows, of cardinality no more than c(n,k), defining a polyhedron that contains exactly the same k integer points. In this case c(n,0)=2^n as in the original case of Doignon-Bell-Scarf for infeasible systems of inequalities. We work on both upper and lower bounds for the constant c(n,k) and discuss some consequences, including a Clarkson-style algorithm to find the l-th best solution of an integer program with respect to the ordering induced by the objective function. [less ▲]

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See detailPressure and velocity on an ogee spillway crest operating at high head ratio: experimental measurements and validation
Peltier, Yann; Dewals, Benjamin ULg; Archambeau, Pierre ULg et al

in Journal of Hydro-Environment Research (in press)

This paper aims at validating pressure and velocity measurements conducted in two physical scale models of an ogee spillway crest operating at heads largely greater than the design head. The design head ... [more ▼]

This paper aims at validating pressure and velocity measurements conducted in two physical scale models of an ogee spillway crest operating at heads largely greater than the design head. The design head of the second model is 50% smaller than the one of the first model. No pier effect or air venting is considered in the study. The velocity field is measured by Bubbles Image Velocimetry. The relative pressure along the spillway crest is measured using pressure sensors. Comparison of measured velocities between both spillways indicates low scale effects, the scaled-profiles collapsing in most parts of the flow. By contrast, measurements of relative pressure along the spillway crest differ for large heads. A theoretical velocity profile based on potential flow theory and expressed in a curvilinear reference frame is fitted to the velocity measurements, considered as reference, for extrapolating the velocity at the spillway crest. Comparing the extrapolated velocity at the spillway crest and the velocity calculated from the relative pressure considering a potential flow finally emphasizes that bottom pressure amplitudes seem overestimated for the larger spillway, while an averaging effect might operate for the pressure measurements on the smaller spillway. [less ▲]

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See detailVideo Games in France and Francophone Belgium. Discourses and cultural legitimation
Delbouille, Julie ULg

in Contemporary French Civilization (in press)

Since its first appearance in the early 1960s, video game has become one of the most popular forms of entertainment in France and francophone Belgium. As for other cultural industries, the last decades ... [more ▼]

Since its first appearance in the early 1960s, video game has become one of the most popular forms of entertainment in France and francophone Belgium. As for other cultural industries, the last decades have seen the emergence of multiple discourses around video game, whether they come from the media, the public or the private sphere. From the themes of violence and addiction to the perception of video game as a cultural object, this paper aims to provide a comprehensive overview of game-related discourses and representations (and their recent evolution) in Francophone Europe. [less ▲]

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See detailCalcium, phosphorus and magnesium in Paediatric Parenteral Nutrition
Fewtrell, mary; Goulet, Olivier; Mihatsch, Walter et al

in Clinical Nutrition (in press)

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See detailOn the finiteness of the weighted likelihood estimator of ability
Magis, David ULg; Verhelst, Norman

in Psychometrika (in press)

The purpose of this note is to focus on the finiteness of the weighted likelihood estimator (WLE) of ability in the context of dichotomous and polytomous item response theory (IRT) models. It is ... [more ▼]

The purpose of this note is to focus on the finiteness of the weighted likelihood estimator (WLE) of ability in the context of dichotomous and polytomous item response theory (IRT) models. It is established that the WLE always returns finite ability estimates. This general result is valid for dichotomous (one-, two-, three- and four-parameter logistic) IRT models, the class of polytomous difference models and divide-by-total models, independently of the number of items, the item parameters and the response patterns. Further implications of this result are outlined. [less ▲]

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See detailInfluence of the secondary endosymbiont Serratia Symbiotica on the resistance to the parasitism in the aphid Acyrthosiphon pisum
Attia, Sabrine; Foray, Vincent; Louâpre, Philippe et al

in Journal of Entomology and Zoology Studies (in press)

Aphids have an obligate association with the primary symbiont Buchnera aphidicola and is known to affect aphid fitness. Aphids commonly harbour other facultative bacterial endosymbionts and may benefit ... [more ▼]

Aphids have an obligate association with the primary symbiont Buchnera aphidicola and is known to affect aphid fitness. Aphids commonly harbour other facultative bacterial endosymbionts and may benefit from their presence through increased resistance to parasitoids [1]. Present results suggest that the ability of hosts to defend against natural enemies depend not only on the presence of symbionts but also on the host genotype. Aphids represent a complex micro-environment for the parasitoid larvae and both the aphid physiology and endosymbiont influence their survival until mummification. [less ▲]

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See detailComment la participation à une recherche contribue au développement professionnel : le cas des exemples à l’Université
Fossion, Gilles ULg; Faulx, Daniel ULg

in Recherches Qualitatives (in press)

La recherche scientifique constitue un des piliers centraux de l’activité universitaire. Nous nous sommes donc questionnés sur les apprentissages générés par celle-ci. Après avoir brièvement décrit les ... [more ▼]

La recherche scientifique constitue un des piliers centraux de l’activité universitaire. Nous nous sommes donc questionnés sur les apprentissages générés par celle-ci. Après avoir brièvement décrit les objectifs et enjeux de cette communication, nous proposons une présentation des objectifs et de la méthodologie de la recherche que nous avons menée au sein des Facultés de Psychologie et des Sciences de l’Éducation de l’Université de Liège. Nous poursuivons, enfin, par la mise en évidence de ses principaux résultats. Ces résultats se situent sur deux niveaux. D’une part, nous présentons les résultats inhérents à la recherche - relative aux impacts générés par la mobilisation de l’exemple au sein du discours pédagogique - et qui contribue à l’enrichissement du champ scientifique abordé. D’autre part, nous abordons les résultats qui permettent la mise en évidence de l’aspect formatif que revêt la participation à une recherche scientifique pour les acteurs. [less ▲]

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See detailA threshold-based weather model for predicting stripe rust infection in winter wheat
El Jarroudi, Moussa ULg; Kouadio, Louis; Bock, Clive et al

in Plant Disease (in press)

Wheat stripe rust (caused by Puccinia striiformis f. sp. tritici) is a major threat in most wheat growing regions worldwide, which potentially causes substantial yield losses when environmental conditions ... [more ▼]

Wheat stripe rust (caused by Puccinia striiformis f. sp. tritici) is a major threat in most wheat growing regions worldwide, which potentially causes substantial yield losses when environmental conditions are favorable. Data from 1999-2015 for three representative wheat-growing sites in Luxembourg were used to develop a threshold-based weather model for predicting wheat stripe rust. First, the range of favorable weather conditions using a Monte Carlo simulation method based on the Dennis model were characterized. Then, the optimum combined favorable weather variables (air temperature, relative humidity, and rainfall) during the most critical infection period (May-June) was identified and was used to develop the model. Uninterrupted hours with such favorable weather conditions over each dekad (i.e., 10-day period) during May-June were also considered when building the model. Results showed that a combination of relative humidity > 92% and 4°C < temperature < 16°C for a minimum of 4 continuous hours, associated with rainfall ≤ 0.1 mm (with the dekad having these conditions for 5-20% of the time), were optimum to the development of a wheat stripe rust epidemic. The model accurately predicted infection events: probabilities of detection were ≥ 0.90 and false alarm ratios were ≤ 0.38 on average, and critical success indexes ranged from 0.63 to 1. The method is potentially applicable to studies of other economically important fungal diseases of other crops or in different geographical locations. If weather forecasts are available, the threshold-based weather model can be integrated into an operational warning system to guide fungicide applications. [less ▲]

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See detailSiblings and the coming out process: a comparative case study
Haxhe, Stéphanie ULg; Cerezo, Alison; Bergfeld, Jeanette et al

in Journal of Homosexuality (in press)

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See detail"'Vive la rose' in Newfoundland: from Alien to Emblem'
Peere, Isabelle ULg

in B.A.S.I.S International Ballad Studies (in press)

This paper traces the song in European tradition through to its ‘revival’ in the 1960s. It analyses Emile’ Benoît's textual and musical recreation of it in the light of my own and other fieldworkers’ ... [more ▼]

This paper traces the song in European tradition through to its ‘revival’ in the 1960s. It analyses Emile’ Benoît's textual and musical recreation of it in the light of my own and other fieldworkers’ accounts of his personality, ethos and creative talent in tradition. The study traces the song's course and progress in Newfoundland, following in the steps of French-Canadian ethno-historian Ronald Labelle’s suggestion that ‘Vive la Rose’ has come to function as identity emblem for Newfoundland’s francophone minority – and even as its representative throughout French-Canada and especially Acadia. [less ▲]

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See detailExperimental passive flutter suppression using a linear tuned vibration absorber
Verstraelen, Edouard ULg; Habib, Giuseppe ULg; Kerschen, Gaëtan ULg et al

in AIAA Journal (in press)

The current drive for increased efficiency in aeronautic structures such as aircraft, wind turbine blades and helicopter blades often leads to weight reduction. A con- sequence of this tendency can be ... [more ▼]

The current drive for increased efficiency in aeronautic structures such as aircraft, wind turbine blades and helicopter blades often leads to weight reduction. A con- sequence of this tendency can be increased flexibility, which in turn can lead to un- favourable aeroelastic phenomena involving large amplitude oscillations and non- linear effects such as geometric hardening and stall flutter. Vibration mitigation is one of the approaches currently under study for avoiding these phenomena. In the present work, passive vibration mitigation is applied to a nonlinear experimental aeroelastic system by means of a linear tuned vibration absorber. The aeroelastic apparatus is a pitch and flap wing that features a continuously hardening restoring torque in pitch and a linear restoring torque in flap. Extensive analysis of the sys- tem with and without absorber at pre-critical and post-critical airspeeds showed an improvement in flutter speed of around 36%, a suppression of a jump due to stall flutter, and a reduction in LCO amplitude. Mathematical modelling of the exper- imental system is used to demonstrate that optimal flutter delay is achieved when two of the system modes flutter at the same flight condition. Nevertheless, even this optimal absorber quickly loses effectiveness as it is detuned. The wind tunnel mea- surements showed that the tested absorbers were much slower to lose effectiveness than those of the mathematical predictions. [less ▲]

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See detailCompte rendu de G. TOUSSAINT, Kreuz und Knochen. Reliquien zur Zeit der Kreuzzüge, Berlin, 2011.
George, Philippe ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailRethinking the Memorable Panel from Pierre Sterckx to Olivier Josso Hamel
Crucifix, Benoît ULg

in European Comic Art (in press), 10(2),

Going back to the origins of the ‘case mémorable’ in the pages of Les Cahiers de la bande dessinée, this article revisits the debates between Pierre Sterckx and Benoît Peeters, articulated around a ... [more ▼]

Going back to the origins of the ‘case mémorable’ in the pages of Les Cahiers de la bande dessinée, this article revisits the debates between Pierre Sterckx and Benoît Peeters, articulated around a conceptual tension between linear and tabular, about the relationship between single panels and narrative. It proposes that the ‘remembered panel’ pinpoints important issues about the recirculation of single images, isolated from their contexts, and the discourse of memory that becomes associated with it. A close-reading of Olivier Josso Hamel’s Au travail, in which the cartoonist redraws his own set of remembered panels, further calls for a reconsideration of Sterckx’s concept in the light of a creative practice that intimately engages with the memory of such panels in a complex relationship to their original narratives. [less ▲]

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See detailVocal change patterns during a teaching day: Inter- and intra-subject variability
Remacle, Angélique ULg; Garnier, Maëva; Gerber, Silvain et al

in Journal of Voice (in press)

Objectives: To describe the mean voice changes of 22 female teachers during a typical workday, examine the inter- and intra-subject variability, and establish a typology of different voice patterns during ... [more ▼]

Objectives: To describe the mean voice changes of 22 female teachers during a typical workday, examine the inter- and intra-subject variability, and establish a typology of different voice patterns during the workday. Methods: For each participant, fundamental frequency (F0), harmonics-to-noise ratio (HNR), jitter, and shimmer were measured on sustained vowels at the beginning and at the end of the workday, at three different times during the school year. Results: The group mean pattern showed significant increases in F0 and HNR during the workday and significant decreases in jitter and shimmer. However, considerable inter- and intra-subject variability was observed. Based on the variation in the acoustic parameters during the workday, three different voice patterns were identified. The first is characterized by a greater F0 increase during the day, interpreted as a common, appropriate adaptation to vocal load. The second is characterized by a greater increase in HNR during the day and greater decreases in jitter and shimmer, interpreted as hyperfunctional voice production. The third is characterized by greater decreases in F0 and HNR and greater increases in jitter and shimmer, suggesting acute inflammation or muscle fatigue following the workday. Conclusions: The observed variety of vocal patterns during the workday emphasizes the need to study this phenomenon individually and target different types of behaviors in order to develop tailored prevention and treatment methods. [less ▲]

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See detailOf Pins and Beads: Note on a Feminine Costume in Mari
Couturaud, Barbara ULg

in Ash-Sharq (in press), 1

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See detailAnalytical and clinical validation of the new Abbot Architect 25(OH)D assay: fit for purpose?
Cavalier, Etienne ULg; LUKAS, Pierre ULg; BEKAERT, Anne-Catherine ULg et al

in Clinical Chemistry & Laboratory Medicine (in press)

BACKGROUND: We provide a clinical and analytical evaluation of the reformulated version of the Abbott Architect 25-hydroxyvitamin D assay. We compared this assay with three commercial automated ... [more ▼]

BACKGROUND: We provide a clinical and analytical evaluation of the reformulated version of the Abbott Architect 25-hydroxyvitamin D assay. We compared this assay with three commercial automated immunoassays and against a VDSP-traceable liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) in six different populations. We also supplemented 40 healthy volunteers with either 600,000 IU of vitamin D2 or 100,000 of vitamin D3 to evaluate the performance of the immunoassays vs. the LC-MS/MS. METHODS: Precision and limit of quantification were assessed, 25(OH)D2 and C3-epimer recovery were calculated. Two hundred and forty samples obtained in healthy Caucasians and Africans, osteoporotic, hemodialyzed and intensive care patients and 3rd trimester pregnant women were analyzed by all methods. Correlation was studied using Passing-Bablok and Bland-Altman analysis. Concordance correlation coefficient (CCC) was calculated to evaluate agreement between immunoassays and LC-MS/MS. We verified if patients were homogeneously classified with the immunoassays when they took vitamin D2 or vitamin D3 after 1, 7 and 28 days. RESULTS: We observed excellent analytical features and showed a very good correlation to the LC-MS/MS results in the overall population. Compared to the other immunoassays, concordance of the new Abbott assay with the LC-MS/MS was at least similar, and often better in diseased populations. Althought the cross-reactivity with 25(OH)D2 was not of 100%, there was no significant difference in the classifications of the patients, either supplemented with D2 or D3 or after 7 or 28 days. CONCLUSIONS: This modified version of the Abbott Architect assay is clearly improved compared to the previous one and presents a better agreement with the LC-MS/MS. [less ▲]

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See detailBeyond survival and uncertainty. The livelihood practices of former Gécamines workers (D.R.Congo)
Rubbers, Benjamin ULg

in Review of African Political Economy (in press)

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See detailThe Sense of Taste in Eighteenth-Century France. Flavours of Silence and Words of Perception
Von Hoffmann, Viktoria ULg

in De achttiende eeuw : Documentatieblad van de Werkgroep Achttiende Eeuw (in press), 48(1-2), 13-27

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See detailFrom thoughts to voices: Understanding the development of auditory hallucinations in schizophrenia
Handest, P; Klimpke, C; Raballo, A et al

in Review of Philosophy and Psychology (in press)

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See detailAmio Acids in PAediatric Parenteral Nutrition
van Goudoever, J; Carnielli, V; Darmaun, D et al

in Clinical Nutrition (in press)

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See detailActivation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment
Dupuis, Nadine ULg; Laschet, Céline ULg; Franssen, Delphine ULg et al

in Molecular Pharmacology (in press)

G protein-coupled receptors are the most important drug targets for human diseases. An important number of them remain devoid of confirmed ligands. GPR27 is one of these orphan receptors, characterized by ... [more ▼]

G protein-coupled receptors are the most important drug targets for human diseases. An important number of them remain devoid of confirmed ligands. GPR27 is one of these orphan receptors, characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion. However, the absence of endogenous or surrogate ligands for GPR27 complicates the examination of its biological function. Our aim was to validate GPR27 signaling pathways and therefore we sought to screen a diversity oriented synthesis library to identify GPR27-specific surrogate agonists. In order to select an optimal screening assay, we investigated GPR27 ligand-independent activity. Both in G protein-mediated pathways and in β-arrestin 2 recruitment, no ligand-independent activity could be measured. However, we observed a recruitment of β-arrestin 2 to a GPR27V2 chimera in the presence of membrane-anchored β-adrenergic receptor kinase 1 (GRK2). Therefore, we optimized a firefly luciferase complementation assay to screen against this chimeric receptor. We identified two compounds (N-[4-(anilinocarbonyl)phenyl]-2,4-dichlorobenzamide (ChemBridge ID5128535) and 2,4-dichloro-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}benzamide (ChemBridge ID5217941)) sharing a N-phenyl-2,4-dichlorobenzamide scaffold, which were selective for GPR27 over its closely related family members GPR85 and GPR173. The specificity of the activity was confirmed with a NanoBiT® β-arrestin 2 assay, imaging of GFP-tagged β-arrestin 2 and PathHunter® β-arrestin 2 Assay. Interestingly, no G protein activation was detected upon activation of GPR27 by these compounds. Our study provides the first selective surrogate agonists for the orphan GPR27. [less ▲]

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See detailDéploiement de dispositifs numériques au sein de nouvelles formes d’organisation : de l’émergence à la stabilisation
Jemine, Grégory ULg

in Sociologies Pratiques (in press), 34

De plus en plus d’organisations du secteur des services s’équipent aujourd’hui de dispositifs numériques variés qui modifient les contextes et les contenus du travail. Ces outils sont présentés comme des ... [more ▼]

De plus en plus d’organisations du secteur des services s’équipent aujourd’hui de dispositifs numériques variés qui modifient les contextes et les contenus du travail. Ces outils sont présentés comme des ingrédients indispensables des modes managériales actuelles qui permettraient à divers dispositifs organisationnels promouvant la flexibilité et la mobilité de s’incarner. La présente contribution propose une étude des ressorts de l’émergence et de la stabilisation de ces dispositifs numériques qui émergent dans le cours de transformations organisationnelles. Nous montrons comment, dans une compagnie d’assurances, les dispositifs numériques sont mobilisés pour répondre à une volonté de « modernisation » de l’organisation et d’optimisation de l’espace de travail. [less ▲]

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See detailImpact of lignin structure on oil production via hydroprocessing with a copperdoped porous metal oxide catalyst
Gillet, sebastien; Petitjean, Laurence; Aguedo, Mario ULg et al

in Bioresource Technology (in press)

A copper-catalyzed depolymerization strategy was employed to investigate the impact of lignin structure on the distribution of hydroprocessing products. Specifically, lignin was extracted from beech wood ... [more ▼]

A copper-catalyzed depolymerization strategy was employed to investigate the impact of lignin structure on the distribution of hydroprocessing products. Specifically, lignin was extracted from beech wood and miscanthus grass. The extracted lignins, as well as a commercial lignin (P1000), were then fractionated using ethyl acetate to provide three different portions for each source of lignin [total of 9 fractions]. Each fraction was structurally characterized and treated with a copper-doped porous metal oxide (Cu-PMO) catalyst under 4 MPa H2 and at 180 °C for 12 hours. The reaction conditions provided notable yields of oil for each fraction of lignin. Analysis of the oils indicated phenolic monomers of commercial interest. The structure of these monomers and the yield of monomer-containing oil was dependent on the origin of the lignin. Our results indicate that hydroprocessing with a Cu-PMO catalyst can selectively provide monomers of commercial interest by careful choice of lignin starting material. [less ▲]

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See detailArt Nouveau in Liège : From Avant-garde to a new Eclectism
Charlier, Sébastien ULg

in Coupdefouet (in press), 28

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See detailSurface Modification of Powder Metallurgy Titanium by Colloidal Techniques and Diffusion Processes for Biomedical Applications
Ureña, Julia; Mendoza Gallego, Carlos ULg; Ferrari, Begoña et al

in Advanced Engineering Materials (in press)

This contribution focuses on modifying the composition and surface characteristics of powder metallurgy titanium substrates to improve their wear resistance and to reduce the surface Younǵs modulus, while ... [more ▼]

This contribution focuses on modifying the composition and surface characteristics of powder metallurgy titanium substrates to improve their wear resistance and to reduce the surface Younǵs modulus, while maintaining the corrosion resistance and biocompatibility. The modification consists of Mo and TiN coatings produced by colloidal techniques which are deposited by electrophoretic deposition (EPD) or spraying onto green or sintered titanium substrates. The final surface structures are formed during a heat treatment, during which diffusion and consolidation of the layers take place. The surfaces are characterised by XRD, SEM, and micro-indentation; showing diffusion areas of between 40 and 85 microns with clear microstructural changes as well as higher hardness values. [less ▲]

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See detailInnovative polyelectrolytes/poly(ionic liquid)s for energy and environment
Ajjan, Fátima N.; Ambrogi, Martina; Tiruye, Girum Ayalneh et al

in Polymer International (in press)

This manuscript presents the work carried out within the European Project RENAISSANCE-ITN, which was dedicated to the development of innovative polyelectrolytes for energy and environmental applications ... [more ▼]

This manuscript presents the work carried out within the European Project RENAISSANCE-ITN, which was dedicated to the development of innovative polyelectrolytes for energy and environmental applications. Within the project different types of innovative polyelectrolytes were synthesized such as poly(ionic liquid)s coming from renewable or natural ions, thiazolium cations, cathechol functionalities or from a new generation of cheap deep-eutectic monomers. Further, macromolecular architectures such as new poly(ionic liquid) block copolymers and new (semi)conducting polymer/polyelectrolyte complexes were also developed. As the final goal, the application of these innovative polymers in energy and environment was investigated. Important advances in energy storage technologies included the development of new carbonaceous materials, new lignin/conducting polymer biopolymer electrodes, new iongels and single-ion conducting polymer electrolytes for supercapacitors and batteries and new poly(ionic liquid) binders for batteries. On the other hand, the use of the innovative polyelectrolytes into sustainable environmental technologies led to the development of new liquid and dry water, new materials for water cleaning technologies such as floculants, oil absorbers, new recyclable organocatalysts platform and multifunctional polymer coatings with antifouling and antimicrobial properties. All in all this article demonstrates the potential of the poly(ionic liquid)s for high-value applications in Energy & Enviromental areas. [less ▲]

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See detailLe cercle de lecture, un dispositif pour construire ensemble des compétences de lecteurs et d'enseignants
Scheepers, Caroline ULg; Outers, Pierre ULg; Werner, Anne-Catherine ULg et al

in Didactiques en Pratique (in press)

Comment accompagner les premiers pas des stagiaires débutants ? À cette vaste et complexe question, le présent article envisage d’apporter un très modeste éclairage. Ainsi, sera décrit, conceptualisé ... [more ▼]

Comment accompagner les premiers pas des stagiaires débutants ? À cette vaste et complexe question, le présent article envisage d’apporter un très modeste éclairage. Ainsi, sera décrit, conceptualisé, analysé et discuté un projet collaboratif qui a associé étroitement théorie et pratique, université et école secondaire, expérimentation et transposition d’un dispositif, didactique disciplinaire et didactique générale. Plus concrètement, il s’est agi de faire expérimenter en tant qu’apprenants un cercle de lecture et un atelier d’écriture par les étudiants romanistes qui suivent le cours de première année de master centré sur la didactique du français langue première, avant de les inviter à transposer l’outil ainsi testé dans leur classe de stage. Seront prises en compte différentes traces : nos consignes, les journaux de stage, les portfolios, les consignes des étudiants, les traces recueillies auprès des élèves du secondaire, les rapports des maitres de stage, etc. Nous verrons in fine que le processus mis en place confirme, toutes proportions gardées, la validité et la pertinence du principe d’homologie entre les activités testées par les stagiaires lors de leur formation initiale à l’université et celles que les formateurs leur recommandent de mettre en œuvre dans leurs classes. [less ▲]

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See detailA Piano Made in Australia: Reinventing an Emblem of Cultural Wealth in Murray Bail's The Voyage
Herbillon, Marie ULg

in Antipodes: A Global Journal of Australian/New Zealand Literature (in press), 31(2),

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See detailAn Equivalent to Represent Inertial and Primary Frequency Control Effects of an External System
Weckesser, Johannes ULg; Van Cutsem, Thierry ULg

in IET Generation, Transmission & Distribution (in press)

This paper presents a novel equivalent, which is suitable for simulation of inertial and primary frequency control effects. In the model reduction procedure, dynamic power injectors are used to replace ... [more ▼]

This paper presents a novel equivalent, which is suitable for simulation of inertial and primary frequency control effects. In the model reduction procedure, dynamic power injectors are used to replace the external system and to mimic its dynamic behavior. The parameters of the equivalents are tuned with a simple approach presented in this paper. The effectiveness of the proposed method is demonstrated on a modified version of the ENTSO-E Dynamic Study Model. The results show that the system frequency response of the unreduced system is retained and a speedup of the simulations of around 4.0 is achieved. [less ▲]

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See detailNew insight on Carboniferous (Viséan) brachiopods from eastern Tafilalt (Morocco)
Mottequin, Bernard; Denayer, Julien ULg; Herbig, Hans-Georg et al

in Geological Journal (in press)

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See detailL'enquête sur le fragment apulien Kiev 147 a
Cuvelier, Graham ULg

in Mètis : Revue d'Anthropologie du Monde Grec Ancien : Philologie, Histoire, Archéologie (in press)

Starting with a drawing of the late 19th century, completed by a recent and unpublished picture, this article presents the journey of an Apulian fragment attributed to the circle of the Darius Painter ... [more ▼]

Starting with a drawing of the late 19th century, completed by a recent and unpublished picture, this article presents the journey of an Apulian fragment attributed to the circle of the Darius Painter. This journey is associated with the history of the research related to this fragment, from its discovery in Ruvo in 1869 until its rediscovery in 2000 in Kiev. Then come a description and an iconographic analysis of the scene depicted on it, followed by the interpretations which have been given to it. [less ▲]

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See detailBaudelaire: traductor auctoritas
Mogollon Zapata, Juan Manuel ULg

in Literatura: Historia, Teoría, Crítica (in press)

Para acceder a una visibilidad médiatica, a una postura reconocible por el público y por sus pares, el traductor se ve obligado a capitalizar espacios de enunciación como los que conceden los prefacios ... [more ▼]

Para acceder a una visibilidad médiatica, a una postura reconocible por el público y por sus pares, el traductor se ve obligado a capitalizar espacios de enunciación como los que conceden los prefacios, la crítica o los retratos biográficos. Es gracias a dichos espacios, en donde el traductor pone en marcha unas estrategias discursivas e institucionales que le permiten posicionar su figura y su proyecto de traduccción, que éste accede al estatuto de traductor-auctoritas, esto es, de instancia dotada de una autoridad simbólica susceptible de conferirle una imagen pública. Un análisis detallado de las estrategias editoriales y de los calculos institucionales que Baudelaire puso en marcha para posicionar su proyecto de traducción de Edgar Poe en la escena literaria del Segundo Imperio nos permitirá demostrar no solo cómo el autor de Las Flores del Mal accede al estatuto de traductor-auctoritas, sino también el rol que jugó su traducción en la construcción de su propia identidad literaria. Reinscribir el proyecto de traducción de Baudelaire en las relaciones de fuerza de un espacio fuertemente jerarquizado, en el cual el escritor busca construir una posición, no sólo nos permite comprender los mecanismos de funcionamiento del espacio institucional en el que se inscribe, sino también los intereses particulares que lo motivan. [less ▲]

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See detailResolved astrometric orbits of ten O-type binaries
Le Bouquin, J.-B.; Sana, H.; Gosset, Eric ULg et al

in Astronomy and Astrophysics (in press)

Our long term aim is to derive model-independent stellar masses and distances for long period massive binaries by combining apparent astrometric orbit with double-lined radial velocity amplitudes (SB2 ... [more ▼]

Our long term aim is to derive model-independent stellar masses and distances for long period massive binaries by combining apparent astrometric orbit with double-lined radial velocity amplitudes (SB2). We follow-up ten O+O binaries with AMBER, PIONIER and GRAVITY at the VLTI. Here, we report about 130 astrometric observations over the last 7 years. We combine this dataset with distance estimates to compute the total mass of the systems. We also compute preliminary individual component masses for the five systems with available SB2 radial velocities. Nine over the ten binaries have their three dimensional orbit well constrained. Four of them are known colliding wind, non-thermal radio emitters, and thus constitute valuable targets for future high angular resolution radio imaging. Two binaries break the correlation between period and eccentricity tentatively observed in previous studies. It suggests either that massive star formation produce a wide range of systems, or that several binary formation mechanisms are at play. Finally, we found that the use of existing SB2 radial velocity amplitudes can lead to unrealistic masses and distances. If not understood, the biases in radial velocity amplitudes will represent an intrinsic limitation for estimating dynamical masses from SB2+interferometry or SB2+Gaia. Nevertheless, our results can be combined with future Gaia astrometry to measure the dynamical masses and distances of the individual components with an accuracy of 5 to 15\%, completely independently of the radial velocities. [less ▲]

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See detailHome Parenteral Nutrition in Paediatrics
Hill, S; Ksiaszyk, J; Prell, C et al

in Clinical Nutrition (in press)

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See detailOrganisational aspects of paediatric parenteral nutrition
Puntis, J; Hojsak, I; Ksiazyk, J et al

in Clinical Nutrition (in press)

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See detailHistoire du thymus : d'un organe vestigial à la programmation de la tolérance immunitaire
Geenen, Vincent ULg

in Medecine Sciences : M/S (in press)

This synthesis presents the most important disruptions of conceptions about the thymus since its discovery in Antique Greece. For centuries, the thymus has been considered as a vestigial organ, and its ... [more ▼]

This synthesis presents the most important disruptions of conceptions about the thymus since its discovery in Antique Greece. For centuries, the thymus has been considered as a vestigial organ, and its role in T-lymphocyte differentiation has been proposed only in the 1960’s. Most recent studies attribute to the thymus an essential and unique role in the programming of central immunological self-tolerance. The basal mechanism implicated in this function is the transcription in thymic epithelium of genes encoding precursors of self-antigens. Processing of these latters leads to presentation of self-antigens by the major histocompatibility complex (MHC) machinery expressed by thymic epithelial and dendritic cells. During fetal life, this presentation drives negative selection of T-cell clones harboring receptors with high affinity for these complexes MHC/self-antigen. After birth, this presentation promotes the generation of regulatory T cells specific for these complexes. A number of studies, as well as the identification of Aire and Fezf2 genes, have shown that a thymus dysfunction plays a crucial role in the development of organ-specific autoimmunity. [less ▲]

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See detailInvestigation on Water Productivity of Winter Wheat Based on MODIS and SEBAL in the Huang-Huai-Hai Plain, China
Yang, Jian-ying; HUO, Zhi-guo; Wu, Ding-rong et al

in Chinese Journal of Agrometeorology (in press)

Understanding how the productivity of water can be increased is widely accepted to be a high priority where water resources are currently scarce and/or over-exploited in China. As the primary data source ... [more ▼]

Understanding how the productivity of water can be increased is widely accepted to be a high priority where water resources are currently scarce and/or over-exploited in China. As the primary data source, MODIS remote sensing, statistics, meteorological data, crop growth period data and ground truth-data from Jan. 2011 to Dec. 2012 were used in actual evapotranspiration estimation, yields rasterizing, and water productivity calculation for winter wheat in the Huang-Huai-Hai Plain (3H Plain). The statistical data were synthesized to calculate district-state-level land productivity, which is then further extrapolated to pixel-level values using a MODIS NDVI image, based on a crop dominance map. Spatial variation of crop water productivity was investigated in order to reveal the key factors of crop water productivity. In addition, the relationship between water productivity and actual evapotranspiration and in subsequence yield for winter wheat was discussed in 3H Plain. The main results indicated that the SEBAL is suitable for estimating evapotranspiration in winter wheat based on the comparation between evapotranspiration measured by Yucheng (in Shandong province). The regional average value of water productivity for winter wheat was detected to be 1.21kg·m-3, with the higher value in Beijing, Tianjin, north part of Shandong province and south part of Hebei province. The pronounced relationship of spatial correlation of the yield and water productivity for winter wheat indicated that the increasing yield governed the increment of water productivity for winter wheat in the coastal land-farming-fishing area (zone1), low plain-hydropenia irrigable land and dry land zone (zone2) and basin- irrigable land and dry land (zone5). The increasing water productivity for winter wheat was recognized to be controlled by rather the increment of yield than the reduction of actual evapotranspiration for winter wheat in the piedmont plain-irrigable land (zone2). Whereas, the pronounced relationship of negative correlation of water productivity and actual evapotranspiration for winter wheat described that only the reduction of actual evapotranspiration was responsible for the increment of water productivity for winter wheat in hill-wet hot paddy-paddy field (zone6). The results is expected to provide a basis information for agricultural water management, improvement of crop water productivity and choice of adaptive mechanism under climate change in Huang-Huai-Hai plain. [less ▲]

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See detailCrystallization and Gelation Behavior of Low- and High Melting Waxes in Rice Bran Oil: a Case-Study on Berry Wax and Sunflower Wax
Doan, Chi Diem; Tavernier, Iris; Bin Sintang, Mohd Dona et al

in Food Biophysics (in press)

Low-melting berry wax (BEW) has proven to be a good oil gelator with a positive contribution to the consistency and flexibility of the structured oil. Nevertheless, the properties of BEWand the ... [more ▼]

Low-melting berry wax (BEW) has proven to be a good oil gelator with a positive contribution to the consistency and flexibility of the structured oil. Nevertheless, the properties of BEWand the corresponding oleogel have not yet been investigated in-depth. In this research, the difference in crystallization and gelling behavior between sunflower wax (SW), a high melting wax, and BEW, a low-melting wax, in rice bran oil (RBO) was investigated. The difference in melting and crystallization temperatures can be explained by the different chemical composition (long-chain wax esters in SWand shortchain fatty acids in BEW). The heterogeneity in crystal habits (unidirectional platelets versus microcrystalline particles) and polymorphism (orthorhombic versus hexagonal) are responsible for the varying gel strength and hardness of the respective SWand BEW-oleogels. The microcrystalline BEW particles aligned and reorganized during 1-month storage at 5 °C, which leaded to an increase in the gel strength and hardness of BEW-oleogel. The gelling property of SW-oleogel however did not significantly differ after 4 weeks at 5 °C, despite of the appearance of spherulitic crystalline clusters. The changes in the physical properties of wax-based oleogels during storage time were further explored using differential scanning calorimetry, polarized light microscope, powder X-ray diffraction and rheology. [less ▲]

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See detailSpecies delimitation in the recalcitrant moss genus Rhynchostegiella (Brachytheciaceae)
Patiño, J.; Hedenäs, L.; Dirkse, G. et al

in Taxon (in press)

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See detailEvaluation of the spatial and economic effectiveness of industrial land policies in Northwest Europe
Vandermeer, Marie-Caroline; Halleux, Jean-Marie ULg

in European Planning Studies (in press)

This article stems from the discrepancy between the lack of attention paid to industrial land policy by academics and the predominant thought among elected representatives and development agencies, i.e ... [more ▼]

This article stems from the discrepancy between the lack of attention paid to industrial land policy by academics and the predominant thought among elected representatives and development agencies, i.e. that industrial land policy plays a key role in the creation of growth and new jobs. The article begins with a reflection on the literature, which stresses the need to develop knowledge on industrial land policies. To help fill this research gap, we have developed an exploratory piece of research on the theme of their spatial and economic effectiveness, on the basis of statistical analyses dedicated to seven countries. As regards spatial effectiveness, the results underline significant national differentials in terms of land consumption on the one hand, while highlighting the economic sprawl that affects France and Belgium on the other hand. As regards economic effectiveness, our results show that the impact of the development of economic estates on growth depends largely on regional contexts. In particular, the “intermediate regions” in western Germany stand out as belonging to a specific context where land policies seem particularly effective from an economic standpoint. By contrast, the economic effectiveness of industrial land policies requires readjustments in most “predominantly rural regions, close to a city”. [less ▲]

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See detailP.Tebt. 526v: A Land Registry from Tebtunis
Nocchi Macedo, Gabriel ULg; Gilbert, Nathan

in Bulletin of the American Society of Papyrologists (in press)

Edition of a Greek land registry from Tebtunis

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See detailTechnological behaviour of Cretaceous and Pliocene clays of northern Morocco used in fired brick manufacturing
El Ouahabi, Meriam ULg; Daoudi, Lahcen; Fagel, Nathalie ULg

in Journal of Materials and Environmental Science (in press)

Northern Morocco has an important local ceramic industry. Twenty-three Craterous and Pliocene clays from Tangier area (Northern Morocco) were studied to test their suitability as raw material for fired ... [more ▼]

Northern Morocco has an important local ceramic industry. Twenty-three Craterous and Pliocene clays from Tangier area (Northern Morocco) were studied to test their suitability as raw material for fired brick production. To assess their behaviour, the chemical composition, specific surface area (SSA), cation exchange capacity (CEC), and apparent density of clays were determined. The chemical composition consisted mainly of SiO2 (32 – 60%), Al2O3 (7 – 30%), and CaO (0.5 – 32%). SSA and CEC values of all the samples were low. The apparent density, pore volume, and micropore values were almost similar. Clay bricks were prepared by forming and shaping, and then fired in the range of 800 – 1100°C. Firing shrinkage, loss on mass and water absorption capacity were done in order to characterize clays after firing. Most of the clay samples have the necessary properties for the manufacturing of brick products. However, some clay samples were above the norm of loss on weight, due mainly to their high amount of carbonates. Furthermore, some kaolinitic samples from Pliocene blue marls and Cretaceous marls are inappropriate for building-related brick fabrication, because of the development of portlandite in brick, when in contact with moisture of the air. However, it will be necessary to mix them with other clays with little or no carbonate to dilute their carbonates content and then enhance their workability. [less ▲]

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See detailAnti-Salmonella activity and probiotic trends of Kluyveromyces marxianus S-2-05 and Kluyveromyces lactis S-3-05 isolated from a French cheese named "Tomme d'Orchies"
Ceugniez, Alexandre; Coucheney, Françoise; Jacques, Philippe et al

in Research in Microbiology (in press)

Kluyveromyces marxianus S-2-05 and Kluyveromyces lactis S-3-05 were recently isolated from a traditional French cheese, Tomme d'Orchies, and characterized here for their advantages using a different ... [more ▼]

Kluyveromyces marxianus S-2-05 and Kluyveromyces lactis S-3-05 were recently isolated from a traditional French cheese, Tomme d'Orchies, and characterized here for their advantages using a different application perspective. First, we established their anti-Salmonella activity and downregulation of the virulence sopD gene of Salmonella enterica subsp. enterica serovar Typhimurium, mainly in the presence of K. marxianus S-2-05. In addition to their antagonism, these non-Saccharomyces yeasts were able to survive under conditions mimicking the gastrointestinal environment and to form biofilms on an abiotic device such as polystyrene. These strains also displayed highly hydrophilic cell wall surfaces properties and capacity for adhesion to intestinal Caco-2 cells, thus enhancing their potential as probiotic strains. [less ▲]

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See detailCan electoral inequalities be legally justified?
Bouhon, Frédéric ULg

in European Review of Public Law (in press), 2016(Automn),

In light of the principle of equality, German, Belgian and British election law contain some legal rules that tend to distribute the faculty to influence the composition of the elected assemblies equally ... [more ▼]

In light of the principle of equality, German, Belgian and British election law contain some legal rules that tend to distribute the faculty to influence the composition of the elected assemblies equally among the governed people, and others that tend to distribute it unequally. The inequality caused by the latter group may be to some extent legally justified by concerns for the general interest, but also provides rulers with means that help them to remain in power, which is hardly justifiable from a legal perspective. In these legal systems, parties are expected to gain a significant portion of the people’s support: not only should the parliament (as a whole) and its members (as individuals) represent the governed people, but the parties themselves are expected to be sufficiently representative of the people in order to access the legislative assemblies. Notably, this thesis draws examples from the case law of the European Court of Human Rights, from which relevant decisions are mentioned here. [less ▲]

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See detailThe Poetics of (In)visibility: A Stylistic Analysis of Caryl Phillips's Foreigners: Three English Lives
Tunca, Daria ULg

in Ariel : A Review of International English Literature (in press)

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See detailClinical usefulness of bone turnover marker concentrations in osteoporosis.
Morris, H. A.; Eastell, R.; Jorgesen, N. R. et al

in Clinica Chimica Acta (in press)

Current evidence continues to support the potential for bone turnover markers (BTM) to provide clinically useful information particularly for monitoring the efficacy of osteoporosis treatment. Many of the ... [more ▼]

Current evidence continues to support the potential for bone turnover markers (BTM) to provide clinically useful information particularly for monitoring the efficacy of osteoporosis treatment. Many of the limitations identified earlier remain, principally in regard to the relationship between BTM and incident fractures. Important data are now available on reference interval values for CTX and PINP across a range of geographic regions and for individual clinical assays. An apparent lack of comparability between current clinical assays for CTX has become evident indicating the possible limitations of combining such data for meta-analyses. Harmonization of units for reporting serum/plasma CTX (ng/L) and PINP (mug/L) is recommended. The development of international collaborations continues with an important initiative to combine BTM results from clinical trials in osteoporosis in a meta-analysis and an assay harmonization program are likely to be beneficial. It is possible that knowledge derived from clinical studies can further enhance fracture risk estimation tools with inclusion of BTM together with other independent risk factors. Further data of the relationships between the clinical assays for CTX and PINP as well as physiological and pre-analytical factors contributing to variability in BTM concentrations are required. [less ▲]

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See detailRobbe-Grillet va plus loin avec l'Express... Le romancier face à l'entretien journalistique
Lorent, Fanny ULg

in Interférences Littéraires = Literaire Interferenties (in press)

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See detailA component method for cold-formed steel beam-to-column bolted gusset plate joints
Bucmys, Zilvinas; Daniunas, Alfonsas; Jaspart, Jean-Pierre ULg et al

in Thin-Walled Structures (in press)

Cold-formed steel elements are being used more frequently on construction sites because of the good strength-to-cost ratio. However, insufficient studies are published examining the properties of these ... [more ▼]

Cold-formed steel elements are being used more frequently on construction sites because of the good strength-to-cost ratio. However, insufficient studies are published examining the properties of these constructions. This paper presents a study of cold formed steel bolted gusset plate connections. A “three springs” mechanical model to calculate joint stiffness is presented. Then the results predicted through the proposed model are validated through comparisons to experimental and finite element results. [less ▲]

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See detailErnst Mach, psychologue de la forme ?
Zincq, Aurélien ULg

in Philosophie (in press)

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See detailEnergy in Paediatric Parenteral Nutrition
Joosten, Koen; Embleton, Nick; Yan, W et al

in Clinical Nutrition (in press)

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See detailAccounting for Price Endogeneity in Airline Itinerary Choice Models: An Application to Continental U.S. Markets
Lurkin, Virginie ULg; Garrow, Laurie; Higgins, Matthew et al

in Transportation Research. Part A : Policy & Practice (in press)

Network planning models, which forecast the profitability of airline schedules, support many critical decisions, including equipment purchase decisions. Network planning models include an itinerary choice ... [more ▼]

Network planning models, which forecast the profitability of airline schedules, support many critical decisions, including equipment purchase decisions. Network planning models include an itinerary choice model which is used to allocate air total demand in a city pair to different itineraries. Multinomial logit (MNL) models are commonly used in practice and capture how individuals make trade-offs among different itinerary attributes; however, none that we are aware of account for price endogeneity. This study formulates an itinerary choice model that is consistent with those used by industry and corrects for price endogeneity using a control function that uses several types of instrumental variables. We estimate our models using database of more than 3 million tickets provided by the Airlines Reporting Corporation. Results based on Continental U.S. markets for May 2013 departures show that models that fail to account for price endogeneity overestimate customers’ value of time and result in biased price estimates and incorrect pricing recommendations. The size and comprehensiveness of our database allows us to estimate highly refined departure time of day preference curves that account for distance, direction of travel, the number of time zones traversed, departure day of week and itinerary type (outbound, inbound or one-way). These time of day preference curves can be used by airlines, researchers, and government organizations in the evaluation of different policies such as congestion pricing. [less ▲]

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See detailTaxonomic significance of variation in sexual condition in Pelekium Mitt. and related genera (Thuidiaceae)
Norhazrina, N.; Patiño, J.; Hedenäs, L. et al

in Journal of Bryology (in press)

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See detailTraduction de "Sense and Its Place in Meaning" de W.V.O. Quine
Moreau, Timothée ULg

in Philosophie (in press)

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See detailOvertopping induced failure of non-cohesive, homogenous fluvial dikes
Rifai, Ismail ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Water Resources Research (in press)

Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of ... [more ▼]

Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of sand-filled fluvial dikes were performed, considering a flow parallel to the dike axis. The breach was triggered by overtopping of the dike crest. A detailed monitoring of the transient evolution of the breach geometry was conducted, providing key insights into the gradual and complex processes involved in fluvial dike failure. The breach develops in two phases: (1) the breach becomes gradually wider and deeper eroding on the downstream side along the main channel, and (2) breach widening controlled by side slope failures, continuing in the downstream direction only. Increasing the inflow discharge in the main channel, the breach formation time decreases significantly and the erosion occurs preferentially on the downstream side. The downstream boundary condition has a strong influence on the breach geometry and the resulting outflow hydrograph. [less ▲]

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See detailComparative assessment of 6-[18F]fluoro-L-m-tyrosine and 6-[18F]fluoro-L-dopa to evaluate dopaminergic presynaptic integrity in a Parkinson’s disease rat model.
Becker, Guillaume ULg; Bahri, Mohamed Ali ULg; Michel, Anne et al

in Journal of Neurochemistry (in press)

Because of the progressive loss of nigro-striatal dopaminergic terminals in Parkinson’s disease (PD), in vivo quantitative imaging of dopamine (DA) containing neurons in animal models of PD is of critical ... [more ▼]

Because of the progressive loss of nigro-striatal dopaminergic terminals in Parkinson’s disease (PD), in vivo quantitative imaging of dopamine (DA) containing neurons in animal models of PD is of critical importance in the pre-clinical evaluation of highly awaited disease-modifying therapies. Among existing methods, the high sensitivity of positron emission tomography (PET) is attractive to achieve that goal. The aim of this study was to perform a quantitative comparison of brain images obtained in 6-hydroxydopamine (6-OHDA) lesioned rats using two dopaminergic PET radiotracers, namely [18F]fluoro-3,4-dihydroxyphenyl-L-alanine ([18F]FDOPA) and 6-[18F]fluoro-L-m-tyrosine ([18F]FMT). Because the imaging signal is theoretically less contaminated by metabolites, we hypothesized that the latter would show stronger relationship with behavioural and post-mortem measures of striatal dopaminergic deficiency. We used a within-subject design to measure striatal [18F]FMT and [18F]FDOPA uptake in eight partially lesioned, eight fully lesioned and ten sham-treated rats. Animals were pretreated with an L-aromatic amino acid decarboxylase (AADC) inhibitor. A catechol-O-methyl transferase inhibitor was also given before [18F]FDOPA PET. Quantitative estimates of striatal uptake were computed using conventional graphical Patlak method. Striatal dopaminergic deficiencies were measured with apomorphine-induced rotations and post-mortem striatal DA content. We observed a strong relationship between [18F]FMT and [18F]FDOPA estimates of decreased uptake in the denervated striatum using the tissue-derived uptake rate constant Kc. However, only [18F]FMT Kc succeeded to discriminate between the partial and the full 6-OHDA lesion and correlated well with the post-mortem striatal DA content. This study indicates that the [18F]FMT could be more sensitive, with respect of [18F]FDOPA, to investigate DA terminals loss in 6-OHDA rats, and open the way to in vivo AADC activity targeting in future investigations on progressive PD models. [less ▲]

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See detailMerging supercritical carbon dioxide and organocatalysis for the precision and green synthesis of poly(lactide)-based (co)polymers
Grignard, Bruno ULg; De Winter, Julien; Gerbaux, Pascal et al

in European Polymer Journal (in press)

Well-defined poly(lactide)-based block copolymers were synthesized by a heterogeneous solvent and metal-free green approach by using organocatalysts in supercritical carbon dioxide (scCO2). We first ... [more ▼]

Well-defined poly(lactide)-based block copolymers were synthesized by a heterogeneous solvent and metal-free green approach by using organocatalysts in supercritical carbon dioxide (scCO2). We first report on the homopolymerization of both L- and D,L- lactide by organocatalyzed Ring-Opening Polymerization (o-ROP) by using a bicomponent organocatalyst composed of a thiourea derivative and various tertiary amines as cocatalysts. Control over the molar mass and dispersity is achieved until high monomer conversion although the polylactides are insoluble in the polymerization medium. The precision synthesis of PLA-based block copolymers from various CO2-phobic hydroxyl end-capped macroinitiators such as polyethylene glycol, polycaprolactone, polybutylene succinate and polyphosphoester was then reported. Merging scCO2 with this organocatalytic system provides therefore a unique tool for the design under solvent-free conditions of poly(lactide)-based block copolymers that are insoluble in scCO2. [less ▲]

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See detailGuided Dive for the Spatial Branch-and-Bound
Gerard, Damien ULg; Koeppe, Matthias; Louveaux, Quentin ULg

in Journal of Global Optimization (in press)

We study the spatial Brand-and-Bound algorithm for the global opti- mization of nonlinear problems. In particular we are interested in a method to find quickly good feasible solutions. Most spatial Branch ... [more ▼]

We study the spatial Brand-and-Bound algorithm for the global opti- mization of nonlinear problems. In particular we are interested in a method to find quickly good feasible solutions. Most spatial Branch-and-Bound-based solvers use a non-global solver at a few nodes to try to find better incumbents. We show that it is possible to improve the branching rules and the node priority by exploiting the solutions from the non-global solver. We also propose several smart adaptive strategies to choose when to run the non-global solver. We show that despite the time spent in solving more NLP problems in the nodes, the new strategies enable the algorithm to find the first good incumbents faster and to prove the global opti- mality faster. Numerous easy, medium size as well as hard NLP instances from the Coconut library are benchmarked. All experiments are run using the open source solver Couenne. [less ▲]

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See detailTropical moss floras: a homogeneous assemblage of highly mobile species? Insights from their spatial patterns of beta diversity
Norhazrina, N.; Wang, J.; Hagborg, A. et al

in Botanical Journal of the Linnean Society (in press)

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See detailBetween Atlantic and Mediterranean: Changes in technology during the Late Glacial in Western Europe and the climate hypothesis
Naudinot, Nicolas; Tomasso, Antonin ULg; Messager, Erwann et al

in Quaternary International (in press)

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See detailComplications of paediatric parenteral nutrition
Decsi, T; Hartman, C; Simchowitz, V et al

in Clinical Nutrition (in press)

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See detailPhysiological and bio-functional properties of gum arabic: a notable interest for certain human diseases
Eloundou Mballa, Pierre; Goffin, Dorothée ULg; Destain, Jacqueline ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

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See detailDiscovery and pharmacological characterization of succinate receptor (SUCNR1/GPR91) agonists
Geubelle, Pierre ULg; Gilissen, Julie; Dilly, Sebastien et al

in British Journal of Pharmacology (in press)

Background and Purpose The succinate receptor (SUCNR1 or GPR91) has been described as a metabolic sensor that may be involved in homeostasis. Notwithstanding its implication in important (patho ... [more ▼]

Background and Purpose The succinate receptor (SUCNR1 or GPR91) has been described as a metabolic sensor that may be involved in homeostasis. Notwithstanding its implication in important (patho)physiological processes, the function of SUCNR1 has remained elusive because no pharmacological tools were available. We report on the discovery of the first family of synthetic potent agonists. Experimental Approach We screened a library of succinate analogues and analysed their activity on SUCNR1. In addition, we modelled a pharmacophore and a binding site for the receptor. New agonists were identified based on the information provided by these two approaches. Their activity was studied in various bioassays, including measurement of cAMP levels, [Ca2+]i mobilisation, TGF-α shedding and recruitment of arrestin 3. The in vivo impact of SUCNR1 activation by these new agonists was evaluated on rat blood pressure. Key Results We identified cis-epoxysuccinic acid and cis-1,2-cyclopropanedicarboxylic acid as agonists with an efficacy similar to the one of succinic acid. Interestingly, cis-epoxysuccinic acid was characterized by a 10 to 20 fold higher potency than succinate on the receptor. For example, cis-epoxysuccinic acid reduced cAMP levels with a pEC50 = 5.57 ± 0.02 (EC50 = 2.7 μM) as compared to succinate pEC50 = 4.54 ± 0.08 (EC50 = 29 μM). The rank order of potency of the three agonists was the same in all bioassays tested. In vivo, cis-epoxysuccinic and cis-1,2-cyclopropanedicarboxylic acid increased rat blood pressure to the same extent as succinate did. Conclusions and Implications We provide new agonist tools for SUCNR1 that should facilitate further research on this understudied receptor. [less ▲]

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See detailA Theory of Soft Capture
Agrell, Per; Gautier, Axel ULg

in Scandinavian Journal of Economics (in press)

n this paper, wee propose a model for regulatory capture that is based on information transmission and asymmetric information. In a three-tier model, a regulator is charged by a political principal to ... [more ▼]

n this paper, wee propose a model for regulatory capture that is based on information transmission and asymmetric information. In a three-tier model, a regulator is charged by a political principal to provide a signal for the type of a regulated firm. Only the firm can observe his type and the production of a correlated signal with a given accuracy is costly for the regulator. The firm can costlessly provide an alternative signal of lower accuracy that is presented to the regulator. In a self-enforcing equilibrium, the regulator transmits the firm-produced signal, internalizes its own savings in information cost and the firm enjoys higher information rents. The main feature of soft capture is that it is not based on a reciprocity of favors but on a congruence of interests between the firm and the regulator. [less ▲]

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See detailLa légation des Pays-Bas et de la Franche-Comté en cour de Rome sous Philippe II (1573-1598). Entre limites institutionnelles et efficacité pragmatique
Regibeau, Julien ULg

in Forum Romanum Belgicum (in press)

Dans le dernier quart du XVIe siècle, Philippe II d’Espagne est à la tête de l’ensemble territorial le plus puissant d’Europe. Fils préféré de l’Église romaine et souverain reconnu d’une grande partie de ... [more ▼]

Dans le dernier quart du XVIe siècle, Philippe II d’Espagne est à la tête de l’ensemble territorial le plus puissant d’Europe. Fils préféré de l’Église romaine et souverain reconnu d’une grande partie de l’Italie, il exerce une influence considérable sur la papauté à travers l’action de son ambassadeur espagnol résidant près le Saint-Siège. Ce dernier a pour tâche d’étendre le réseau des alliés au sein de la Curie. Il chapeaute aussi les différents services diplomatiques et ecclésiastiques des États de la monarchie présents dans la cité des papes . Si elle conserve une certaine autonomie, la légation des Pays-Bas et de la Franche-Comté près le Saint-Siège – conduite par l’agent Laurent du Blioul de 1573 à 1598 – est également soumise à la volonté de cet envoyé. Ce n’est d’ailleurs pas un hasard si l’étude de la légation à l’époque du règne de Philippe II a peu passionné les historiens . Effacée derrière la puissance de l’ambassadeur espagnol, celle-ci semble être un piètre avatar des services ecclésiastiques et diplomatiques dépêchés à Rome par les ducs de Bourgogne , Philippe le Beau ou les archiducs Albert et Isabelle . Or, si, aux temps de Laurent du Blioul, la légation, considérée en tant qu’actrice isolée dans le paysage romain, joue un rôle modeste qui se cantonne au suivi des affaires ecclésiastiques provenant des Pays-Bas et de la Franche-Comté, il faut envisager qu’elle fait partie intégrante d’une toile religieuse, diplomatique, sociale et politique plus vaste tissée à Rome par le roi Philippe II et ses agents. Dépassant les seuls intérêts des Pays-Bas, l’étude de cette institution conduit à appréhender tout un pan de la stratégie politique habsbourgeoise. L’imbrication de la légation dans le théâtre diplomatique espagnol à Rome a deux facettes : si, d’une part, elle limite les prérogatives institutionnelles de l’agent du Blioul, d’autre part, elle favorise régulièrement l’efficacité de son action. [less ▲]

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See detailDe culpable a perseguido: Baudelaire y el proceso de Las Flores del mal
Mogollon Zapata, Juan Manuel ULg

in Revista Historia, Teoría, Crítica (in press)

¿Cómo el poeta de Las Flores del Mal paso de ser un autor proscrito, y en consecuencia sospechoso, al autor perseguido e incomprendido que ha inmortalizado la historia literaria? ¿Cómo Baudelaire pudo ... [more ▼]

¿Cómo el poeta de Las Flores del Mal paso de ser un autor proscrito, y en consecuencia sospechoso, al autor perseguido e incomprendido que ha inmortalizado la historia literaria? ¿Cómo Baudelaire pudo desviar a su favor una circunstancia que, a primera vista, era desafortunada? Baudelaire supo utilizar el escándalo que provocó la publicación de Las Flores del Mal para promover su figura pública. Un análisis de las posturas discursivas desplegadas por Baudelaire y por sus pares durante y después del proceso nos permitirá comprender mejor la inversión que el poeta hace de su condenación al transformar la sanción penal y moral, y la exclusión a la que ésta conduce, en un signo de su grandeza y de su gloria póstuma. [less ▲]

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See detailMorphology of the UV aurorae Jupiter during Juno’s first perijove observations
Bonfond, Bertrand ULg; Gladstone, G. R.; Grodent, Denis ULg et al

in Geophysical Research Letters (in press)

On 27 August 2016, the NASA Juno spacecraft performed its first close-up observations of Jupiter during its perijove. Here we present the UV images and color ratio maps from the Juno-ultraviolet ... [more ▼]

On 27 August 2016, the NASA Juno spacecraft performed its first close-up observations of Jupiter during its perijove. Here we present the UV images and color ratio maps from the Juno-ultraviolet spectrometer UV imaging spectrograph acquired at that time. Data were acquired during four sequences (three in the north, one in the south) from 5:00 UT to 13:00 UT. From these observations, we produced complete maps of the Jovian aurorae, including the nightside. The sequence shows the development of intense outer emission outside the main oval, first in a localized region (255 ∘ –295 ∘ System III longitude) and then all around the pole, followed by a large nightside protrusion of auroral emissions from the main emission into the polar region. Some localized features show signs of differential drift with energy, typical of plasma injections in the middle magnetosphere. Finally, the color-ratio map in the north shows a well-defined area in the polar region possibly linked to the polar cap. [less ▲]

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See detailLa collaboration entre architectes et plasticiens à Liège dans les années 1930.
Charlier, Sébastien ULg

in In Situ, revue des patrimoines (in press), 26

En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales ... [more ▼]

En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales, le mensuel revendique une vision transversale de l’architecture où la réflexion plastique occupe une place centrale. Dès le départ, elle s’associe à Anthologie, revue imprégnée des théories futuristes et qui diffuse les artistes de l’avant-garde locale. D’abord par le biais de l’édition et des expositions, plasticiens et architectes travaillent ensuite ensemble dans le cadre de projets ambitieux financés par les pouvoirs publics. Cette contribution revient aux racines de cette collaboration en définissant les liens théoriques ou personnels unissant les deux revues. En se concentrant sur les infrastructures publiques, elle comment les artistes et les architectes ont répondu ensemble aux exigences concrètes de la commande en les replaçant dans le contexte social, politique et économique d’une ville belge de seconde importance à la veille de la Seconde Guerre mondiale. [less ▲]

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See detailOutcome after failure of allogeneic hematopoietic stem cell transplantation in children with acute leukemia: a study by the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC)
Rorhlich; Roux, C; Tifratene, K et al

in Bone Marrow Transplantation (in press)

Allogeneic hematopoietic stem cell transplantation (SCT) contributes to improved outcome in childhood acute leukemia (AL). However, therapeutic options are poorly defined in case of post-transplantation ... [more ▼]

Allogeneic hematopoietic stem cell transplantation (SCT) contributes to improved outcome in childhood acute leukemia (AL). However, therapeutic options are poorly defined in case of post-transplantation relapse. We aimed to compare treatment strategies in 334 consecutive children with acute leukemia relapse or progression after SCT in a recent ten-year period. Data could be analyzed in 288 patients (157 ALL, 123 AML and 8 biphenotypic AL) with a median age of 8.16 years at transplantation. The median delay from first SCT to relapse or progression was 182 days. The treatment consisted in chemotherapy alone (n=108), chemotherapy followed by second SCT (n=70), supportive/palliative care (n=67), combination of chemotherapy and DLI (n=30), or isolated reinfusion of donor lymphocytes (DLI) (n=13). The median OS duration after relapse was 164 days and differed according to therapy: DLI after chemotherapy = 385 d, second allograft = 391d, chemotherapy = 174d, DLI alone = 140d, palliative care = 43d. A second SCT or a combination of chemotherapy and donor lymphocytes infusion yielded similar outcome (HR=0.85, p=0.53) unlike chemotherapy alone (HR 1.43 p=0.04), palliative care (HR=4.24, p<0.0001) or isolated DLI (HR=1,94, p<0.04). Despite limitations in this retrospective setting, strategies including immunointervention appear superior to other approaches, mostly in AML. [less ▲]

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See detailEpistémologie de la théorie du complot
Jamin, Jérôme ULg

in Cahiers de l'Éducation Permanente (Les) (in press)

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See detailComprehensive Human Papilloma Virus (HPV) Genotyping in Cervical Squamous Cell Carcinomas and its Relevance to Cervical Cancer Prevention in Malawian Women
Howitt, Brooke; Herfs, Michael ULg; Tomoka, Tamiwe et al

in Journal of Global Oncology (in press)

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See detailRecycling Mitsunobu coupling: a shortcut for troublesome esterifications
Menhour, Boudjema; Obounou Akong, Firmin; Mayon, Patrick et al

in Tetrahedron (in press)

An unusual recycling Mitsunobu reaction proved to be successful to couple two fragments in the course of the synthesis of the hydrophobic moiety of rhamnolipid derivatives. Based on the obtained pivotal ... [more ▼]

An unusual recycling Mitsunobu reaction proved to be successful to couple two fragments in the course of the synthesis of the hydrophobic moiety of rhamnolipid derivatives. Based on the obtained pivotal intermediate, a one pot ‘cross-metathesis/reduction’ approach gave access to structural variations of the side chains. Further study of these molecules will contribute to a better understanding of the role of the lipid moiety in immunostimulatory and plant defense eliciting properties. [less ▲]

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See detailOnderhandelen over vorming van een meerderheid en burgemeester worden in België : Welke invloed heeft de regionale wetgeving ?
Grandjean, Geoffrey ULg

in Chroniques de Droit Public = Publiekrechtelijke Kronieken (in press)

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See detailMilk-clotting properties of plant rennets and their enzymatic, rheological and sensory role in cheese making: a Review
Ben Amira, Amal; Besbes, Souhail; Attia, Hamadi et al

in International Journal of Food Properties (in press)

Plant rennets hold an important position amongst various coagulants used in cheese technology. The selection of a suitable plant coagulant is important due to the increasing global demands of cheese ... [more ▼]

Plant rennets hold an important position amongst various coagulants used in cheese technology. The selection of a suitable plant coagulant is important due to the increasing global demands of cheese alongside reduced supply of calf rennet. Thus, a literature synthesis is presented to investigate recent achievements on their functional properties and enzymatic role in cheese making. Efforts have also been done to compare certain rheological and sensory properties of final products, arising from some plant and animal based rennets. In fact, some coagulants such as actinidin or dubiumin produce cheeses with sensory qualities similar to those produced by animal rennet. Others, like ginger, cucumisin or hieronymain proteases contribute to develop very different textures and flavors, due to excessive proteolytic activity and production of bitter peptides. For milk-clotting enzymes with high non-specific action, several improvement strategies have been developed to produce cheeses with sensory properties close to those of animal rennet. For example, the mixture of coagulants (cardosins/chymosin), the selection of appropriate milk or its ultrafiltration, as well as the increase of salting time of cheese during ripening could be efficient ways to improve texture and reduce bitterness. Concerning cheeses with high yield loss, the whey could be used for a traditional production of whey cheese. To conclude, the selection of appropriate plant rennet with high MCA/PA ratio and the optimization of all coagulation parameters play a central role in manufacturing cheese with superior rheological and sensory properties. [less ▲]

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See detail"'Les orphelins sur la tombe de leur mère' at the Crossing with Flemish Tradition"
Peere, Isabelle ULg

in B.A.S.I.S - International Ballad Studies (in press)

The study proposes a comparative analysis of the French-language and Flemish/Dutch versions of the international ballad deriving from the Danish 'Moderen under Mulde' (Dgf 89), and on this basis ... [more ▼]

The study proposes a comparative analysis of the French-language and Flemish/Dutch versions of the international ballad deriving from the Danish 'Moderen under Mulde' (Dgf 89), and on this basis identifies three French-language texts recorded in North-east France and Wallonia yet showing closer affinities to the neighbouring Flemish tradition. In the light of both textual traditions, their unilateral adoption of Flemish motifs and their enhancing effect suggests deliberate selection rather than mere geographical proximity or bilingualism as explanation for their hybridization. [less ▲]

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See detailDe la quantité de demandeurs d’emploi à la qualité de l’accompagnement. Des professionnels entre « esprit gestionnaire » et relation de service
Remy, Céline ULg; Lavitry, Lynda

in Revue Française de Socio-Economie (in press)

L’article explore les liens et les zones de tension entre les politiques de mesure de la performance et la qualité de l’accompagnement à l’emploi telle qu’elle est définie dans les pratiques et discours ... [more ▼]

L’article explore les liens et les zones de tension entre les politiques de mesure de la performance et la qualité de l’accompagnement à l’emploi telle qu’elle est définie dans les pratiques et discours des agents et prestataires des services publics de l’emploi en France et en Belgique francophone. L’objectif est de démontrer que le pilotage du travail des intermédiaires de l’emploi par les indicateurs de mesure donne lieu à des pratiques, parfois clandestines, de mise en conformité avec le rendement statistique de leur activité. Mais parallèlement, les excès d’une quantification perçue comme abusive ou dangereuse pour leur ethos professionnel poussent une partie d’entre eux à agir en contradiction avec ces principes gestionnaires et ce, au nom de l’intérêt du demandeur d’emploi et de la prise en compte de la qualité des emplois, tendances que l’on décèle dans les deux pays étudiés. [less ▲]

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See detailDécider ensemble ou vivre ensemble. Quelques pas de danse sur un air de tango
Bouhon, Frédéric ULg

in Revue de la Faculté de Droit de l'Université de Liège (in press), 2017/1

Il s'agit de la version publiée de la leçon inaugurale prononcée le 10 novembre 2016.

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See detailAdvances in diagnosis and management of familial pituitary adenomas
JEDIDI, Haroun ULg; ROSTOMYAN, Lilith; POTORAC, Iulia et al

in International Journal of Endocrine Oncology (in press)

Familial pituitary adenomas accounts for approximately 5-8 % of all pituitary adenomas. Besides the adenomas occurring as part of syndromic entities that bring together several endocrine or other systems ... [more ▼]

Familial pituitary adenomas accounts for approximately 5-8 % of all pituitary adenomas. Besides the adenomas occurring as part of syndromic entities that bring together several endocrine or other systems disorders, 2-3% of the familial pituitary adenomas fit into the familial isolated pituitary adenomas (FIPA) syndrome. 20% of FIPA syndromes have shown mutations in the AIP gene and have distinct clinical characteristics. Recent findings have isolated a new non-AIP FIPA syndrome called X-LAG, resulting from duplication in GPR-101 gene. These new advances in the field of pituitary disease are opening up a new challenging domain to both clinician and researcher. This review will focus on these last findings and their contribution to the diagnosis and the management of familial pituitary adenomas. [less ▲]

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See detailMetals as chemical tracers to discriminate ecological populations of threatened Franciscana dolphins (Pontoporia blainvillei) from Argentina
Romero, M.B.; Polizzi, P.; Chiodi, L. et al

in Environmental Science and Pollution Research (in press)

Franciscana dolphins are the most impacted small cetacean in the Southwestern Atlantic Ocean, classified as Vulnerable A3d by IUCN. Essential (Fe, Mo, Mn, Cr, Ni, Co) and non-essential (Ag, Pb, Sn) trace ... [more ▼]

Franciscana dolphins are the most impacted small cetacean in the Southwestern Atlantic Ocean, classified as Vulnerable A3d by IUCN. Essential (Fe, Mo, Mn, Cr, Ni, Co) and non-essential (Ag, Pb, Sn) trace elements (TEs) were measured in liver, kidney, and brain samples of by-catch Franciscana dolphins that were living in estuarine (n = 21) and marine (n = 21) habitats (1) to assess whether TEs posed a threat and (2) to evaluate the suitability of TEs for discriminating ecological populations of this species in Argentinean waters. Essential TEs showed little variation in tissues from both groups in agreement with levels reported for other cetaceans and suggesting that these concentrations correspond to normal physiological levels. Non-essential TEs were higher in estuarine juveniles and adults dolphins than in marine specimens. These results suggest anthropogenic sources associated with estuarine area and that Franciscana dolphins are good sentinels of the impact of the environment. The difference in the concentrations of TEs beetwen ecological populations appeared to be related to distinct exposures in both geographical areas, and it is suggested that Ag and Sn concentrations in adults are good chemical tracers of anthropogenic input of TEs. These results provide additional information for improved management and regulatory policy. [less ▲]

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See detailModeling structures in fire with SAFIR®: Theoretical background and capabilities
Franssen, Jean-Marc ULg; Gernay, Thomas ULg

in Journal of Structural Fire Engineering (in press)

Purpose: This paper describes the theoretical background and main hypotheses at the basis of SAFIR®, a nonlinear finite element software for modeling structures in fire. The paper also explains how to use ... [more ▼]

Purpose: This paper describes the theoretical background and main hypotheses at the basis of SAFIR®, a nonlinear finite element software for modeling structures in fire. The paper also explains how to use the software at its full extent. The discussed numerical modeling principles can be applied with other similar software. Approach: Following a general overview of the organization of the software, the thermal analysis part is explained, with the basic equations and the different possibilities to apply thermal boundary conditions (compartment fire, localized fire, etc.). Next, the mechanical analysis part is detailed, including the time integration procedures and the different types of finite elements: beam, truss, shell, spring and solid. Finally, the material laws are described. The software capabilities and limitations are discussed throughout the paper. Findings: By accommodating multiple types of finite elements and materials, by allowing the user to consider virtually any section type and to input the fire attack in multiple forms, the software SAFIR® is a comprehensive tool for investigating the behavior of structures in the fire situation. Meanwhile, being developed exclusively for its well-defined field of application, it remains relatively easy to use. Value: The paper will improve the knowledge of readers (researchers, designers and authorities) about numerical modeling used in structural fire engineering in general and the capabilities of a particular software largely used in the fire engineering community. [less ▲]

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See detailSurvivances et métamorphoses. Les gemmes isiaques remployées au Moyen Âge et leur interprétation
Veymiers, Richard ULg

in Anabases : Traditions et Réception de l'Antiquité (in press)

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See detailMultivariate analysis of 18F-DMFP PET data to assist the diagnosis of parkinsonism
Segovia, Fermin; Gorriz, Juan M.; Ramirez, Javier et al

in Frontiers in Neuroinformatics (in press)

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