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See detailCombined Local and Centralized Voltage Control in Active Distribution Networks
Soleimani Bidgoli, Hamid ULiege; Van Cutsem, Thierry ULiege

in IEEE Transactions on Power Systems (in press)

A two-level real-time voltage control scheme is proposed to keep voltages within specified limits in distribution grids using Distributed Generation Units (DGUs). It combines a local and a centralized ... [more ▼]

A two-level real-time voltage control scheme is proposed to keep voltages within specified limits in distribution grids using Distributed Generation Units (DGUs). It combines a local and a centralized control of their reactive powers. The local control provides fast response after a disturbance, reducing its impact and enhancing voltage quality. The centralized control uses measurements collected throughout the network to bring the voltages inside tighter limits and balance the various DGU contributions. To this purpose, it adjusts in a coordinated way their reactive power set-points, taking into account the local controls. This discrete control solves at each time step a multi-time-step constrained optimization inspired of Model Predictive Control. The method effectiveness is demonstrated on a 75-bus test system hosting 22 DGUs. [less ▲]

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See detailStochastic Inventory Routing for Perishable Products
Crama, Yves ULiege; Rezaei Sadrabadi, Mahmood ULiege; Savelsbergh, Martin et al

in Transportation Science (in press)

Different solution methods are developed to solve an inventory routing problem for a perishable product with stochastic demands. The solution methods are compared empirically in terms of average profit ... [more ▼]

Different solution methods are developed to solve an inventory routing problem for a perishable product with stochastic demands. The solution methods are compared empirically in terms of average profit, service level, and actual freshness. The benefits of explicitly considering demand uncertainty are quantified. The computational study highlights that in certain situations a simple ordering policy can already reach a very good performance, but that statistically and economically significant improvements are achieved when using more advanced solution methods. Managerial insights concerning the impact of shelf life and store capacity on profit are also obtained. [less ▲]

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See detail1. IV Rois 15, 26-34 ; 18, 30-33 ; 18, 37-19, 2
Carlig, Nathan ULiege

in Journal of Coptic Studies (in press)

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See detailA method for independent component graph analysis of resting-state fMRI. Brain and Behavior 2017, in press
Ribeiro de Paula, Demetrius; Ziegler, Erik; Abeyasinghe, P et al

in Brain and Behavior (in press)

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See detailEffect of feed enzymes on digestibility and growth in weaned pigs: A systematic review and meta-analysis
Torres-Pitarch, Alberto; Hermans, David; Manzanilla, Edgar Garcia et al

in Animal Feed Science & Technology (in press)

Supplementation of post-weaning diets with exogenous enzymes has been suggested to control post-weaning syndrome, by compensating for the under-developed endogenous enzyme secretory capacity and ... [more ▼]

Supplementation of post-weaning diets with exogenous enzymes has been suggested to control post-weaning syndrome, by compensating for the under-developed endogenous enzyme secretory capacity and increasing nutrient digestibility in newly weaned pigs. The effect of in-feed enzymes in improving gut maturation, growth and/or health in weaned piglets is not always consistent. A systematic review and a meta-analysis were therefore conducted to determine which exogenous enzymes are most consistent in improving piglet growth and digestibility when supplemented to post-weaning diets. The mean difference effect of enzyme supplementation on growth and digestibility of dry matter (DM), gross energy (GE), crude protein (CP), and P digestibility was calculated for each study and this was used as the effect size estimate in the meta-analysis. The impact of feed enzyme supplementation on intestinal health and bone mineralization was also discussed where information was available in the literature. From a total of 90 studies included in the metaanalysis, G:F was improved in 55, remained un-changed in 28 and deteriorated in 7, in response to enzyme supplementation. Average daily gain, average daily feed intake (ADFI) and G:F was improved when phytase was supplemented in the diet. Phosphorous digestibility was increased with phytase supplementation while GE digestibility was reduced. Dietary phytase supplementation increased bone mineralization in pigs fed diets with a reduced Pcontent. Supplementation with multi-enzyme complexes increased DM and CP digestibility. In conclusion, the most consistent improvement in piglet growth, P digestibility and bone mineralization were found due to exogenous phytase supplementation. Supplementation with xylanase alone or in combination with β-glucanase had inconsistent effects on piglet growth and nutrient digestibility. The most consistent improvements in growth and nutrient digestibility due to supplementation with multi-enzymes complexes were found when mannanase and/or protease were included in the complex. [less ▲]

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See detailMercury stable isotopes discriminate different populations of European seabass and trace potential Hg sources around Europe
Cransveld, Alice; Amouroux, David; Tessier, Emmanuel et al

in Environmental Science & Technology (in press)

Our study reports the first data on mercury (Hg) isotope composition in marine European fish, for seven distinct populations of the European seabass, Dicentrarchus labrax. The use of δ20230 Hg and Δ19931 ... [more ▼]

Our study reports the first data on mercury (Hg) isotope composition in marine European fish, for seven distinct populations of the European seabass, Dicentrarchus labrax. The use of δ20230 Hg and Δ19931 Hg values in SIBER enabled us to estimate Hg isotopic niches, successfully discriminating several populations. Recursive-partitioning analyses demonstrated the relevance of Hg stable isotopes as discriminating tools. Hg isotopic values also provided insight on Hg contamination sources for biota in coastal environment. The overall narrow range of δ202 Hg around Europe was suggested to be related to a global atmospheric contamination while δ202 Hg at some sites was linked either to background ontamination, or with local contamination sources. Δ199 Hg was related to Hg levels of fish but we also suggest a relation with ecological conditions. Throughout this study, results from the Black Sea population stood out, displaying a Hg cycling similar to fresh water lakes. Our findings bring out the possibility to use Hg isotopes in order to discriminate distinct populations, to explore the Hg cycle on a large scale (Europe) and to distinguish sites contaminated by global versus local Hg source. The interest of using Hg sable isotopes to investigate the whole European Hg cycle is clearly highlighted. [less ▲]

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See detailFirst results in the use of milk mid-infrared spectra in the detection of lameness in Austrian dairy cows
Mineur, Axelle ULiege; Köck, Astrid; Grelet, Clément ULiege et al

in Agriculturae Conspectus Scientificus (in press)

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See detailEtre avec par corps. L'expérience du commun sur un plateau de théâtre
Servais, Véronique ULiege; Brahy, Rachel ULiege

in Recherches en Communication (in press)

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See detailDe culpable a perseguido: Baudelaire y el proceso de Las Flores del mal
Mogollon Zapata, Juan Manuel ULiege

in Revista Historia, Teoría, Crítica (in press)

¿Cómo el poeta de Las Flores del Mal paso de ser un autor proscrito, y en consecuencia sospechoso, al autor perseguido e incomprendido que ha inmortalizado la historia literaria? ¿Cómo Baudelaire pudo ... [more ▼]

¿Cómo el poeta de Las Flores del Mal paso de ser un autor proscrito, y en consecuencia sospechoso, al autor perseguido e incomprendido que ha inmortalizado la historia literaria? ¿Cómo Baudelaire pudo desviar a su favor una circunstancia que, a primera vista, era desafortunada? Baudelaire supo utilizar el escándalo que provocó la publicación de Las Flores del Mal para promover su figura pública. Un análisis de las posturas discursivas desplegadas por Baudelaire y por sus pares durante y después del proceso nos permitirá comprender mejor la inversión que el poeta hace de su condenación al transformar la sanción penal y moral, y la exclusión a la que ésta conduce, en un signo de su grandeza y de su gloria póstuma. [less ▲]

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See detailReply to "Stimulus, response and excitability - What is new?"
WANG, François-Charles ULiege

in Clinical Neurophysiology (in press)

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See detailDual action of neuro-estrogens in the regulation of male sexual behavior
Cornil, Charlotte ULiege; de Bournonville, Catherine

in General and Comparative Endocrinology (in press)

Estrogens derived from brain testosterone aromatization (neuro-estrogens) are critical for the activation of male sexual behavior. Their effects on this behavior are typically associated with long-term ... [more ▼]

Estrogens derived from brain testosterone aromatization (neuro-estrogens) are critical for the activation of male sexual behavior. Their effects on this behavior are typically associated with long-term changes in circulating levels of testosterone and the transcriptional activity of their liganded nuclear receptors. According to this view, neuro-estrogens would prime the neural circuits controlling the long-term expression of behavior, which would then be acutely regulated by neurotransmitter systems conveying information from the social environment. In parallel, neuro-estrogens are also able to produce much faster effects than previously anticipated. Our recent investigations in Japanese quail revealed an interesting dichotomy in the regulation of male sexual behavior by membrane- and nuclear-initiated estrogen signaling providing respectively an acute modulation of sexual motivation and a long-term control of the capacity to display the copulatory sequence. In parallel, a similar dichotomy applies to the regulation of brain aromatase whose expression depends on the transcriptional activity of testosterone metabolites while its enzymatic activity is rapidly regulated in a region- and context-dependent manner. Recent evidences suggest that rapid changes in sexual motivation result from rapid changes in local estrogen production. Together, these data support the idea that the acute regulation of some aspects of male sexual behavior depends not only on classical neurotransmitter systems, but also on rapid and spatially restricted changes in local estrogen availability. The existing literature suggests that this acute regulation by neuro-estrogens of the motivational aspects of behavior could be generalized to other systems such as singing behavior in songbirds. [less ▲]

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See detailUse of multi-element stable isotope ratios to investigate ontogenetic movements of Micropogonias furnieri in a tropical Brazilian estuary
Pizzochero, Ana Carolina; Michel, Loïc ULiege; Chenery, Simon et al

in Canadian Journal of Fisheries & Aquatic Sciences (in press)

The whitemouth croaker, Micropogonias furnieri, is a long-lived fish of high commercial importance in the Western Atlantic Ocean. Here, we used stable isotope ratios of carbon, sulfur and nitrogen and ... [more ▼]

The whitemouth croaker, Micropogonias furnieri, is a long-lived fish of high commercial importance in the Western Atlantic Ocean. Here, we used stable isotope ratios of carbon, sulfur and nitrogen and isotopic niche metrics (SIBER) to study feeding habits and track habitat use by whitemouth croakers in Guanabara Bay, an estuary in Rio de Janeiro state, Brazil. Our results highlighted size-related habitat segregation, with small juvenile (< 30 cm) fishes residing mostly inside estuaries, while large adult (> 60 cm) fishes feed mainly in Continental Shelf (CS) waters. Medium adult fishes (30-60 cm) appear to feed in multiple coastal and CS habitats. Moreover, their feeding ecology showed strong temporal differences, linked with seasonal and, to a lesser extent, inter-annual variation in oceanographic features of the ecosystem in which they live. Overall, these differences in ecological features suggest that (1) adult and juvenile whitemouth croakers should be treated as different components of the food web and (2) the conservation of these habitats should be prioritized to better manage and sustain the coastal fisheries in Guanabara Bay. [less ▲]

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See detailThe miR-183/ItgA3 axis is a key regulator of prosensory area during early inner ear development
Van Den Ackerveken, Priscilla ULiege; Mounier, Anaïs ULiege; Huyghe, Aurélia et al

in Cell Death & Differentiation (in press)

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See detailNow we're free. De lichtheid van Leonard Cohen in You want it darker (2016)
Mus, Francis ULiege

in Passage, tijdschrift voor Europese literatuur en cultuur (in press)

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See detailFluid and Electrolytes (Na, Cl and K) in Paediatric Parenteral Nutrition
Jochum, Franck; Moltu, Sissel; SENTERRE, Thibault ULiege et al

in Clinical Nutrition (in press)

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See detailA push–pull strategy to control aphids combines intercropping with semiochemical releases
Xu, Qingxuan ULiege; Hatt, Séverin ULiege; Chevalier Mendes Lopes, Thomas ULiege et al

in Journal of Pest Science (in press)

Even if insect pest populations can be reduced by increasing plant diversity through intercropping, natural enemies are not always favored in such systems. Alternatively, semiochemical substances have ... [more ▼]

Even if insect pest populations can be reduced by increasing plant diversity through intercropping, natural enemies are not always favored in such systems. Alternatively, semiochemical substances have been tested to enhance biological control, with inconsistent results. Combining both strategies can be an interesting way to maximize pest control. In this work, a 2-year setup involving wheat–pea strip intercropping combined with the release of E-b-farnesene (EBF) or methyl salicylate (MeSA) was tested as a push–pull strategy to simultaneously repel aphids and attract beneficials. Two types of slow-release formulation (i.e., oil and alginate beads) containing EBF or MeSA were deployed with the intercropping. The abundance of aphids was significantly decreased, while hoverfly larvae and mummified aphids increased on both pea plants and wheat tillers by the release of oil-formulated EBF and MeSA. The proportion parasitism of the aphid-parasitism rate [mummies/(aphids + mummies)] was also increased by treating both crops in both years. Releasing EBF through oil rather than alginate beads proved significantly better for attracting natural enemies and reducing aphids. Aphids were negatively correlated with the density of hoverflies (both adults and larvae) and numbers of mummies. All these results showed that combining intercropping with the release of EBF or MeSA formulated in oil can significantly reduce aphid density and attract their natural enemies. Therefore, the combination of both strategies could help farmers reduce the use of insecticides. [less ▲]

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See detailHome Parenteral Nutrition in Paediatrics
Hill, S; Ksiaszyk, J; Prell, C et al

in Clinical Nutrition (in press)

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See detailNew insights on the Picasso’s Blue Period painting La famille Soler through non-invasive imaging and analytical techniques
Defeyt, Catherine ULiege; Walter, Philippe; Rousselière, Hélène et al

in Studies in Conservation (in press)

The material study of La Famille Soler through non-invasive imaging, molecular, structural and elemental techniques, permitted a relevant re-examination of this singular blue period painting, which is ... [more ▼]

The material study of La Famille Soler through non-invasive imaging, molecular, structural and elemental techniques, permitted a relevant re-examination of this singular blue period painting, which is considered as the earliest Picasso’s version of Le déjeuner sur l’herbe by E. Manet. On the one hand, it was concluded that the underlying landscape painted by Vidal in 1903 referred to Manet’s masterpiece. On the other hand, it was assumed that the cubist sketch undertaken by Picasso in 1912, prior to the current blue background, consists of an uncompleted transformation of Vidal’s landscape into synthetic cubism. Additionally, the main pigments associated to the underlying compositions were successfully identified. [less ▲]

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See detailDisrupted Self in Alzheimer’s disease: beyond midline structures: Commentary on Wong et al.
Genon, Sarah ULiege; Salmon, Eric

in Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (in press)

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See detailJean Desquesnes : Il primo libro de madrigali a cinque voci (Anvers, Phalèse et Bellère, 1594). Edition critique
Degroote, Frédéric ULiege

in Revue de la Société Liégeoise de Musicologie (in press)

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See detailStandard versus individualized parenteral nutrition
Riskin, A; Picaud, J-C; Shamir, R et al

in Clinical Nutrition (in press)

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See detailOrganisational aspects of paediatric parenteral nutrition
Puntis, J; Hojsak, I; Ksiazyk, J et al

in Clinical Nutrition (in press)

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See detailSurvivances et métamorphoses. Les gemmes isiaques remployées au Moyen Âge et leur interprétation
Veymiers, Richard ULiege

in Anabases : Traditions et Réception de l'Antiquité (in press)

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See detailSupplementation with 80,000 IU vitamin D3/month between November and April corrects vitamin D insufficiency without overdosing: Effect on serum 25-hydroxyvitamin D serum concentrations.
Tournier, Herve; Tran, Nicole; Dray, Nathalie et al

in Presse medicale (Paris, France : 1983) (in press)

INTRODUCTION: Vitamin D insufficiency, defined by a 25-hydroxyvitamin D (25OHD) serum concentration<20ng/mL, is highly frequent in the French general population, especially between November and April. The ... [more ▼]

INTRODUCTION: Vitamin D insufficiency, defined by a 25-hydroxyvitamin D (25OHD) serum concentration<20ng/mL, is highly frequent in the French general population, especially between November and April. The aim of this study was to evaluate whether 80,000 IU vitamin D3 every month during this period of the year was able to maintain a 25OHD level between 20 and 60ng/mL in apparently healthy subjects whatever their basal vitamin D status. METHODS: Ninety-eight subjects volunteered to receive an 80,000 IU vitamin D3 dose every month between November 2014 and April 2015. Serum 25OHD, calcemia and calciuria were measured just before the first dose (Month 0), just before the 4th dose (M4), and one month after the 6th dose (M7). RESULTS: At M0, 25OHD was 17.5+/-9.5ng/mL. Sixty subjects (61.2%) had a 25OHD<20ng/mL and 25 (25.5%) had a 25OHD<10ng/mL. 25OHD increased significantly at M4 (35.3+/-8.0ng/mL) and M7 (40.1+/-8.5) without change in calcemia and calciuria. At M4, 2 subjects had a 25OHD slightly below 20ng/mL (17.6 and 19.7ng/mL), and none had a concentration>60ng/mL. At M7, all had a serum 25OHD>20ng/mL and 2 subjects had a value slightly above 60ng/mL (62.1 and 63.2ng/mL). CONCLUSION: A monthly supplementation with 80,000 IU vitamin D3 between November and April corrected vitamin D insufficiency in subjects in whom it was initially very frequent, without overdosing. This protocol is simple, safe and costless, and can be easily implemented when physicians detect risk factors for hypovitaminosis D in patients for whom a 25OHD measurement is not indicated. [less ▲]

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See detailPulse-Based Control Using Koopman Operator Under Parametric Uncertainty
Sootla, Aivar; Ernst, Damien ULiege

in IEEE Transactions on Automatic Control (in press)

In applications, such as biomedicine and systems/synthetic biology, technical limitations in actuation complicate implementation of time-varying control signals. In order to alleviate some of these ... [more ▼]

In applications, such as biomedicine and systems/synthetic biology, technical limitations in actuation complicate implementation of time-varying control signals. In order to alleviate some of these limitations, it may be desirable to derive simple control policies, such as step functions with fixed magnitude and length (or temporal pulses). In this technical note, we further develop a recently proposed pulse-based solution to the convergence problem, i.e., minimizing the convergence time to the target exponentially stable equilibrium, for monotone systems. In particular, we extend this solution to monotone systems with parametric uncertainty. Our solutions also provide worst-case estimates on convergence times. Furthermore, we indicate how our tools can be used for a class of non-monotone systems, and more importantly how these tools can be extended to other control problems. We illustrate our approach on switching under parametric uncertainty and regulation around a saddle point problems in a genetic toggle switch system. [less ▲]

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See detailGlobal structural integrity and effective connectivity in patients with disorders of consciousness
BODART, Olivier ULiege; Amico, Enrico; Gomez, Francisco et al

in Brain Stimulation (in press)

Background Previous studies have separately reported impaired functional, structural, and effective connectivity in patients with disorders of consciousness (DOC). The perturbational complexity index (PCI ... [more ▼]

Background Previous studies have separately reported impaired functional, structural, and effective connectivity in patients with disorders of consciousness (DOC). The perturbational complexity index (PCI) is a transcranial magnetic stimulation (TMS) derived marker of effective connectivity. The global fractional anisotropy (FA) is a marker of structural integrity. Little is known about how these parameters are related to each other. Objective We aimed at testing the relationship between structural integrity and effective connectivity. Methods We assessed 23 patients with severe brain injury more than 4 weeks post-onset, leading to DOC or locked-in syndrome, and 14 healthy subjects. We calculated PCI using repeated single pulse TMS coupled with high-density electroencephalography, and used it as a surrogate of effective connectivity. Structural integrity was measured using the global FA, derived from diffusion weighted imaging. We used linear regression modelling to test our hypothesis, and computed the correlation between PCI and FA in different groups. Results Global FA could predict 74% of PCI variance in the whole sample and 56% in the patients' group. No other predictors (age, gender, time since onset, behavioural score) improved the models. FA and PCI were correlated in the whole population (r = 0.86, p < 0.0001), the patients, and the healthy subjects subgroups. Conclusion We here demonstrated that effective connectivity correlates with structural integrity in brain-injured patients. Increased structural damage level decreases effective connectivity, which could prevent the emergence of consciousness. [less ▲]

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See detailBelgian and Swiss service providers faced with the challenge of jobseeker guidance. Predominance of stakeholder games or of the collaborative framework?
Remy, Céline ULiege

in International Review of Administrative Sciences (in press)

The public employment services have contracted out their jobseeker guidance role to service providers. The paper focuses on how the collaboration between the public services and private employment ... [more ▼]

The public employment services have contracted out their jobseeker guidance role to service providers. The paper focuses on how the collaboration between the public services and private employment operators is organised in Belgium and Switzerland. These partnerships have to contend with two challenges, which are the recruitment of candidates for training projects and the measurement of the results of the service. Our initial hypothesis supports the idea that stakeholder games are more effective in solving critical situations than the collaborative framework. The international comparison allows us to vary the partnership creation methods and to show a particular articulation between the stakeholder games and collaborative framework. [less ▲]

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See detailSuivre ou guider son public ? Le rapport aux lecteurs dans le Journal historique et littéraire de l’antiphilosophe François-Xavier de Feller
Teicher, Elie ULiege

in Revue Belge de Philologie et d'Histoire (in press), 95

In the eighteenth century, literary journals have set a specific relationship with their readers. By publishing letters from the public and by answering to their demands (or not), the journalists have ... [more ▼]

In the eighteenth century, literary journals have set a specific relationship with their readers. By publishing letters from the public and by answering to their demands (or not), the journalists have established a readers’ community that share a common cultural universe. This article aims at analyzing the relationship between the antiphilosophe François-Xavier de Feller and the readership of his Journal historique et littéraire. The journalist, who wishes to fight against the philosophes and to spread his own radical ideas above all, has however taken his public’s capacity of reaction into account. This article will question the mechanisms of this relationship by considering the letters from the public to the editor but also Feller’s own addresses to his readership published in the journal. Even if he refuses the idea that every man is able to use his own critical reason, the journalist has been influenced by his readership but, more importantly, he has maintained in his public a new form of criticism, radically opposed to the ideas of Enlightenment. [less ▲]

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See detailFaux coupables et vrais imposteurs: usurpation d'identité et justice dans la Chanson d'Ami et Amile.
Henrard, Nadine ULiege

in Cahiers de Recherches Médiévales et Humanistes = Journal of Medieval and Humanistic Studies (in press), (2017 (2)),

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See detailLa fratrie comme nouvelle unité stable? Vers une évolution des pratiques en contexte de placement.
Haxhe, Stéphanie ULiege; Léonard, Serge; Casman, Marie-Thérèse ULiege et al

in Cahiers de Psychologie Clinique (in press), 50

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See detailSalinity impact on seed yield, polyphenols composition and antioxidant activity of Fennel (Foeniculum vulgarae Mill) extracts
Bettaieb ép Rebey, Ines ULiege; Bourgou, S.; Marzouk, B. et al

in Journal of new sciences (in press)

Recently, medicinal and aromatic plants have received much attention in several fields such agroalimentary, perfumes, pharmaceutical industries and natural cosmetic products. The consumption of herbal ... [more ▼]

Recently, medicinal and aromatic plants have received much attention in several fields such agroalimentary, perfumes, pharmaceutical industries and natural cosmetic products. The consumption of herbal medicines is widespread and is continuously increasing worldwide. Although, secondary metabolites in the medicinal and aromatic plants were fundamentally produced by genetic processing but, their biosynthesis is strongly influenced by environmental factors. Salinity is one of the major factors that affect essential oil biosynthesis and secretion (Heuer et al. 2002). In Tunisia, salt-affected soils cover about 10% of the total area of the country. Salinity led to biochemical disorders and can change plant behaviour regarding the biosynthesis of primary and secondary metabolites. Among all the secondary metabolites synthesized by plants, phenolic compounds are some of the most widespread. In this context, this research evaluated the effect of salinity on total and individual polyphenols contents as well as the antioxidant activities of fennel (Foeniculum vulgarae Mill.) seeds of two geographic origins, Tunisia (TFS) and Egypt (EFS). This plant is one of the most common aromatics in the Mediterranean kitchen. Plants were treated with different concentrations of NaCl treatment: 0, 50, and 75 mmoL. Plant growth was significantly reduced with the severity of saline treatment. This also caused important reductions in the seed yield and yield components. Besides, total polyphenol content was higher in treated seeds, and salinity improved the amount of individual phenolic compounds. Moreover, antioxidant activities of the extracts were determined by four different test systems, namely 2,2-diphenyl-1-picrylhydrazyl, β-carotene/linoleic acid chelating, and reducing power assays. The highest antioxidant activities were reveled in severe stressed plants for both TFS and EFS. In this case, fennel seeds produced under saline conditions may function as a potential source of antioxidant compounds, which could support the utilization of this plant in a large field of applications such as food industry. [less ▲]

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See detailSteady-State, Nonlinear Analysis of Large Arrays of Electrically Actuated Micromembranes Vibrating in a Fluid
Halbach, Alexandre ULiege; Geuzaine, Christophe ULiege

in Engineering with Computers (in press)

This paper describes a robust and efficient method to obtain the steady-state, nonlinear behaviour of large arrays of electrically actuated micromembranes vibrating in a fluid. The nonlinear ... [more ▼]

This paper describes a robust and efficient method to obtain the steady-state, nonlinear behaviour of large arrays of electrically actuated micromembranes vibrating in a fluid. The nonlinear electromechanical behavior and the multiple vibration harmonics it creates are fully taken into account thanks to a multiharmonic finite element formulation, generated automatically using symbolic calculation. A domain decomposition method allows to consider large arrays of micromembranes by efficiently distributing the computational cost on parallel computers. Two- and three- dimensional examples highlight the main properties of the proposed method. [less ▲]

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See detailAn Optimal Control Formulation of Pulse-Based Control Using Koopman Operator
Sootla, Aivar; Mauroy, Alexandre; Ernst, Damien ULiege

in Automatica (in press)

In many applications, and in systems/synthetic biology in particular, it is desirable to compute control policies that force the trajectory of a bistable system from one equilibrium (the initial point) to ... [more ▼]

In many applications, and in systems/synthetic biology in particular, it is desirable to compute control policies that force the trajectory of a bistable system from one equilibrium (the initial point) to another equilibrium (the target point), or in other words to solve the switching problem. It was recently shown that, for monotone bistable systems, this problem admits easyto-implement open-loop solutions in terms of temporal pulses (i.e., step functions of fixed length and fixed magnitude). In this paper, we develop this idea further and formulate a problem of convergence to an equilibrium from an arbitrary initial point. We show that this problem can be solved using a static optimization problem in the case of monotone systems. Changing the initial point to an arbitrary state allows to build closed-loop, event-based or open-loop policies for the switching/convergence problems. In our derivations we exploit the Koopman operator, which offers a linear infinite-dimensional representation of an autonomous nonlinear system. One of the main advantages of using the Koopman operator is the powerful computational tools developed for this framework. Besides the presence of numerical solutions, the switching/convergence problem can also serve as a building block for solving more complicated control problems and can potentially be applied to non-monotone systems. We illustrate this argument on the problem of synchronizing cardiac cells by defibrillation. Potentially, our approach can be extended to problems with different parametrizations of control signals since the only fundamental limitation is the finite time application of the control signal. [less ▲]

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See detailDébattre la mesure : l’imagination sociologique de Steve Reich
Orianne, Jean-François ULiege

in Revue Française d'Etudes Americaines (in press)

This article aims to identify the contributions of Steve Reich's music to sociology. His music reveals three main characteristics: it is made out of empirical material collected on the field; it is a ... [more ▼]

This article aims to identify the contributions of Steve Reich's music to sociology. His music reveals three main characteristics: it is made out of empirical material collected on the field; it is a theory of processes; it is a political and cultural act. Steve Reich's music affects sociology on these three points: it reminds the sociologist the nature of his craft and his commitment to the social world, questions his methods and practice; it even sheds light on his own concepts (in particular that of “process”). The author proposes to extract from Steve Reich’s compositional work some useful elements for the profession of sociologist. [less ▲]

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See detailLa rencontre des crépuscules: à propos d'une transaction entre les bibliophiles Jules Vandenpeereboom (1843-1917) et Raoul Warocqué (1870-1917)
Adam, Renaud ULiege; Federinov, Bertrand

in De Gulden Passer = Le compas d'or (in press), 95(2017),

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See detailIntensity and memory characteristics of near-death experiences
Martial, Charlotte ULiege; Charland-Verville, Vanessa ULiege; Cassol, Helena ULiege et al

in Consciousness & Cognition (in press)

Memories of Near-Death Experiences (NDEs) seem to be very detailed and stable over time. At present, there is still no satisfactory explanation for the NDEs’ rich phenomenology. Here we compared ... [more ▼]

Memories of Near-Death Experiences (NDEs) seem to be very detailed and stable over time. At present, there is still no satisfactory explanation for the NDEs’ rich phenomenology. Here we compared phenomenological characteristics of NDE memories with the reported experience’s intensity. We included 152 individuals with a self-reported “classical” NDE (i.e. occurring in life-threatening conditions). All participants completed a mailed questionnaire that included a measure of phenomenological characteristics of memories (the Memory Characteristics Questionnaire; MCQ) and a measure of NDE’s intensity (the Greyson NDE scale). Greyson NDE scale total score was positively correlated with MCQ total score, suggesting that participants who described more intense NDEs also reported more phenomenological memory characteristics of NDE. Using MCQ items, our study also showed that NDE’s intensity is associated in particular with sensory details, personal importance and reactivation frequency variables. [less ▲]

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See detailA Nineteenth-Century National Prussian Macroseismic Questionnaire
Knuts, Elisabeth ULiege; Hinzen, K-H; Reamer, S.K. et al

in Seismological Research Letters (in press)

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See detail‘Quality by Design’ approach for the analysis of impurities in pharmaceutical drug products and drug substances
Dispas, Amandine ULiege; Avohou, Tonakpon Hermane ULiege; Lebrun, Pierre ULiege et al

in Trends in Analytical Chemistry (in press)

The pharmaceutical industry is highly regulated by quality policies. The concept of risk management is strongly integrated into the quality assurance system to ensure pharmaceuticals’ quality and ... [more ▼]

The pharmaceutical industry is highly regulated by quality policies. The concept of risk management is strongly integrated into the quality assurance system to ensure pharmaceuticals’ quality and patients’ safety. In the context of quality control, the detection of impurities in raw materials and finished products is a major concern. It can be challenging for analytical scientists to meet specificity/selectivity and sensitivity requirements. Obviously, separation techniques are widely used for the detection of impurities but the method development required to achieve Analytical Target Profile (ATP) concerns is often challenging. Therefore, to ensure pragmatic and systematic methods development and simultaneously manage the risk associated with analytical methods, the principles of Quality by Design (QbD) should be applied. This paper provides an overview of QbD principles and statistical strategies (mainly DoE-DS approach) which can be applied to impurity detection methods, as well as a review of the literature where QbD has been applied to these types of analytical methods. [less ▲]

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See detailHow can new players establish themselves in highly institutionalized labour markets? A Belgian case study in the area of project-based work
Xhauflair, Virginie ULiege; Huybrechts, Benjamin ULiege; Pichault, François ULiege

in British Journal of Industrial Relations (in press)

How can new players seeking to serve nonstandard worker categories (such as project-based workers) establish themselves into labour markets that are highly institutionalized? This paper explores the case ... [more ▼]

How can new players seeking to serve nonstandard worker categories (such as project-based workers) establish themselves into labour markets that are highly institutionalized? This paper explores the case of SMart, a Belgian community-based labour market intermediary that successfully developed solutions to better represent the interests of project-based workers and secure their discontinuous careers. Using an organizational legitimacy approach, we find that labour market entry and growth involve different types of boundary-crossing when addressing the needs of workers that do not fit into established categories. However, to justify boundary-crossing, the new player must complement its pragmatic work on delivering new services and tools with conceptual (cognitive) and structural (moral) legitimation work. [less ▲]

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See detailEdible cyanobacterial genus Arthrospira: actual state of the art in cultivation methods, genetics and application in medicine
Furmaniak, Magda; Misztak, Agnieszka; Franczuk, Martyna et al

in Frontiers in Microbiology (in press)

The cyanobacterial genus Arthrospira appears very conserved and has been divided into five main genetic clusters on the basis of molecular taxonomy markers. Genetic studies of seven Arthrospira strains ... [more ▼]

The cyanobacterial genus Arthrospira appears very conserved and has been divided into five main genetic clusters on the basis of molecular taxonomy markers. Genetic studies of seven Arthrospira strains, including genome sequencing of seven strains, have enabled a better understanding of those photosynthetic prokaryotes. Even though genetic manipulations have not yet been performed with success, many genomic and proteomic features such as stress adaptation, nitrogen fixation or biofuel production have been characterized. Many of above-mentioned studies aimed to optimize the cultivation conditions. Factors like the light intensity and quality, the nitrogen source or different modes of growth (auto-, hetero- or mixotrophic) have been studied in detail. The scaling-up of the biomass production using photobioreactors, either closed or open, was also investigated to increase the production of useful compounds.. The richness of nutrients contained in the genus Arthrospira can be used for promising applications in the biomedical domain. Ingredients such as the calcium spirulan, immulina, C‐phycocyanin and γ‐linolenic acid (GLA) show a strong biological activity. Recently, its use in the fight against cancer cells was documented in many publications. The health-promoting action of 'Spirulina' has been demonstrated in the case of cardiovascular diseases and age-related conditions. Some compounds also have potent immunomodulatory properties, promoting the growth of beneficial gut microflora, acting as antimicrobial and antiviral. Products derived from Arthrospira were shown to successfully replace biomaterial scaffolds in regenerative medicine. Supplementation with the cyanobacterium also improves the health of livestock and quality of the products of animal origin. They were also used in cosmetic preparations. [less ▲]

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See detailCyclic and Fatigue Behaviour of Rock Materials: Review, Interpretation and Research Perspectives
Cerfontaine, Benjamin ULiege; Collin, Frédéric ULiege

in Rock Mechanics & Rock Engineering (in press)

The purpose of this paper is to provide a comprehensive state of the art of fatigue and cyclic loading of natural rock materials. Papers published in the literature are classified and listed in order to ... [more ▼]

The purpose of this paper is to provide a comprehensive state of the art of fatigue and cyclic loading of natural rock materials. Papers published in the literature are classified and listed in order to ease bibliographical review, to gather data (sometimes contradictory) on classical experimental results and to analyse the main interpretation concepts. Their advantages and limitations are discussed, and perspectives for further work are highlighted. The first section summarises and defines the different experimental set-ups (type of loading, type of experiment) already applied to cyclic/fatigue investigation of rock materials. The papers are then listed based on these different definitions. Typical results are highlighted in next section. Fatigue/cyclic loading mainly results in accumulation of plastic deformation and/or damage cycle after cycle. A sample cyclically loaded at constant amplitude finally leads to failure even if the peak load is lower than its monotonic strength. This subcritical crack is due to a diffuse microfracturing and decohesion of the rock structure. The third section reviews and comments the concepts used to interpret the results. The fatigue limit and S–N curves are the most common concepts used to describe fatigue experiments. Results published from all papers are gathered into a single figure to highlight the tendency. Predicting the monotonic peak strength of a sample is found to be critical in order to compute accurate S–N curves. Finally, open questions are listed to provide a state of the art of grey areas in the understanding of fatigue mechanisms and challenges for the future. [less ▲]

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See detailQuality of life perception by inmates in the Central Prison of Mbuji-Mayi, Democratic Republique of Congo
Kalonji, Muasa Patoka ULiege; Okenge Ngongo, Leon; Ilunga Ilunga, Félicien et al

in International Journal of Medecal Research & Health Sciences (in press)

Summary Introduction: In developing countries, quality of prison life remains a challenge in public health. The present study aimed at determining the quality of life as perceived by inmates during their ... [more ▼]

Summary Introduction: In developing countries, quality of prison life remains a challenge in public health. The present study aimed at determining the quality of life as perceived by inmates during their imprisonment at the Central Prison of Mbuji-Mayi, Democratic Republic of Congo. Materials and Methods: This cross-sectional study was carried out over a 3-month period (between December 2015 and February 2016) at the Central Prison of Mbuji-Mayi. Three hundred inmates participated to the survey. The World Health Organisation Quality of Life Scale (WHOQOL-BREF) was used to estimate health and problems affecting inmates’ everyday life. Results: Mean age of inmates was 33 ± 10 years (range: 18-70 years) and most of them were male (88.7%). The quality of life score they estimated was below 50, on the WHOQOL-BREF scale weighted over 100 points (average overall score: 26±7). When considering each WHOQOL-BREF domain, the lowest scores (0-100 normalised scale) were registered for: perception of physical health (24±11), psychological health (18±8), social relationship (39±15) and environmental relationships (24±8). Overall, inmates aged over 30 years old presented an average score slightly lower than younger inmates (25±6 vs. 27±7; p=0.005). Depending on the length of incarceration, the average score was lower for inmates imprisoned for more than 6 months compared to others (26±6 vs. 28 ± 8; p= 0.015). Correlations between domain scores were low but statistically significant; no correlation was highlighted between environment and mental health domains. Conclusion: Most inmates considered their quality of life as negative, regardless of the WHOQOL-BREF domain. Efforts to improve quality of life should remain a priority for political authorities. [less ▲]

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See detailStellar parameters for TRAPPIST-1
Van Grootel, Valérie ULiege; Silva Fernandes, Catarina ULiege; Gillon, Michaël ULiege et al

in Astrophysical Journal (in press)

TRAPPIST-1 is an ultracool dwarf star transited by seven Earth-sized planets, for which thorough characterization of atmospheric properties, surface conditions encompassing habitability and internal ... [more ▼]

TRAPPIST-1 is an ultracool dwarf star transited by seven Earth-sized planets, for which thorough characterization of atmospheric properties, surface conditions encompassing habitability and internal compositions is possible with current and next generation telescopes. Accurate modeling of the star is essential to achieve this goal. We aim to obtain updated stellar parameters for TRAPPIST- 1 based on new measurements and evolutionary models, compared to those used in discovery studies. We present a new measurement for the parallax of TRAPPIST-1, 82.4 $\pm$ 0.8 mas, based on 188 epochs of observations with the TRAPPIST and Liverpool Telescopes from 2013 to 2016. This revised parallax yields an updated luminosity of $L_*=(5.22\pm0.19)\times 10^{-4} L_{\odot}$, very close to the previous estimate but almost twice more precise. We next present an updated estimate for TRAPPIST-1 stellar mass, based on two approaches: mass from stellar evolution modeling, and empirical mass derived from dynamical masses of equivalently classified ultracool dwarfs in astrometric binaries. We combine them through a Monte-Carlo approach to derive a semi-empirical estimate for the mass of TRAPPIST-1. We also derive estimate for the radius by combining this mass with stellar density inferred from transits, as well as estimate for the effective temperature from our revised luminosity and radius. Our final results are $M_*=0.089 \pm 0.006 M_{\odot}$, $R_* = 0.121 \pm 0.003 R_{\odot}$, and $T_{\rm eff} =$ 2516 $\pm$ 41 K. Considering the degree to which TRAPPIST-1 system will be scrutinized in coming years, these revised and more precise stellar parameters should be considered when assessing the properties of TRAPPIST-1 planets. [less ▲]

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See detailDispersal and alternative breeding site fidelity strategies in an amphibian
Denoël, Mathieu ULiege; Dalleur, séverine; Langrand, Estelle et al

in Ecography (in press)

Dispersal (i.e., movement from a natal or breeding site to another breeding site) is a central process in ecology and evolution as it affects the eco-evolutionary dynamics of spatially structured ... [more ▼]

Dispersal (i.e., movement from a natal or breeding site to another breeding site) is a central process in ecology and evolution as it affects the eco-evolutionary dynamics of spatially structured populations. Dispersal evolution is regulated by the balance between costs and benefits, which is influenced by the individual phenotype (i.e., phenotype-dependent dispersal) and environmental factors (i.e., condition-dependent dispersal). Even though these processes have been extensively studied in species with simple life cycles, our knowledge about these mechanisms in organisms displaying complex life cycles remains fragmentary. In fact, little is specifically known about how the interplay between individual and environmental factors may lead to alternative dispersal strategies that, in turn, lead to the coexistence of contrasted site fidelity phenotypes. In this paper, we examined breeding dispersal in a pond-breeding amphibian, the great crested newt (Triturus cristatus), within usual walking distances for a newt. We took advantage of recent developments in multi-event capture-recapture models and used capture-recapture data (946 newts marked) collected in a spatially structured population occupying a large pond network (73 ponds). We showed a high rate of breeding site infidelity (i.e., pond use) and the coexistence of two dispersal phenotypes, namely, a highly pond faithful phenotype and a dispersing phenotype. Individuals that were site faithful at time t-1 were therefore more likely to remain site faithful at time t. Our results also demonstrated that the probability that individuals belong to one or the other dispersal phenotypes depended on environmental and individual factors. In particular, we highlighted the existence of a dispersal syndrome implying a covariation pattern among dispersal behavior, body size, and survival. Our work opens new research prospects in the evolution of dispersal in organisms displaying complex life cycles and raises interesting questions about the evolutionary pathways that contribute to the diversification of movement strategies in the wild. [less ▲]

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See detailLes prestataires belges et suisses à l’épreuve de l’accompagnement des demandeurs d’emploi. Prédominance des jeux d’acteurs ou du cadre de collaboration ?
Remy, Céline ULiege

in Revue Internationale des Sciences Administratives (in press), 86(1),

Les services publics de l’emploi ont délégué leur mission d’accompagnement des chômeurs aux prestataires de service. L’article s’intéresse au déroulement des collaborations entre services publics et ... [more ▼]

Les services publics de l’emploi ont délégué leur mission d’accompagnement des chômeurs aux prestataires de service. L’article s’intéresse au déroulement des collaborations entre services publics et opérateurs privés d’emploi, en Belgique et en Suisse. Ces partenariats sont confrontés à deux épreuves qui sont le recrutement des candidats dans les projets de formation et la mesure des résultats de la prestation. Notre hypothèse initiale soutient l’idée que les jeux d’acteurs ont plus d’effet dans la résolution des situations critiques que le cadre de collaboration. La comparaison internationale nous permet de faire varier les modalités de création des partenariats et de montrer une articulation particulière entre jeux d’acteurs et cadre de collaboration. [less ▲]

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See detailSustainable biofuel: a question of scale and aims
Ciervo, Margherita ULiege; Schmitz, Serge ULiege

in Moravian Geographical Reports (in press), 25(4),

The predominant production model of Bioenergy, which is based on first-generation biofuels developed on a global scale, creates ecological impacts throughout the production chain, resulting in a paradox ... [more ▼]

The predominant production model of Bioenergy, which is based on first-generation biofuels developed on a global scale, creates ecological impacts throughout the production chain, resulting in a paradox, as well as social unrest and territorial conflict. This paper focuses on agro-energy and second-generation biofuels, investigating the structural differences, the advantages, the potential problems and the possible solutions of some local biofuel initiatives in North-Western Europe. [less ▲]

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See detailPersonnalité borderline et tatouage : Hippolyte et le corps-en-disparition
Englebert, Jérôme ULiege; Follet, Valérie

in Cahiers de Psychologie Clinique (in press)

Based on the analysis of a clinical case, namely a borderline patient displaying several self-realised tattoos, we’ll broach three principal characteristics of borderline existence. They are instantaneity ... [more ▼]

Based on the analysis of a clinical case, namely a borderline patient displaying several self-realised tattoos, we’ll broach three principal characteristics of borderline existence. They are instantaneity, ubiquity and a sense of disappearing-body. Given this original understanding of the trouble, the issue of tattoo practice in borderline people, as well as the very particular relationship they maintain with their own body and other people, will be discussed. We’ll also highlight the dialectics between the objectification of the body, as an object which is likely to be manipulated and modified, and the objectivation of the body, as an object dotted with the special and determining power of being animated by a subjectivity. We’ll end by emphasising how the borderline personality find its place and is, in a way, in tune with the postmodern evolution of our current society. [less ▲]

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See detailAnorexia nervosa and first-person perspective: Altruism, family system and body experience
Englebert, Jérôme ULiege; Follet, Valérie; Valentiny, Caroline

in Psychopathology (in press)

Based on the case study of Jeanne, the objective of this article is to study patterns of anorexic people’s specific subjectivity. We seek to identify, in a first-person perspective, the core vulnerability ... [more ▼]

Based on the case study of Jeanne, the objective of this article is to study patterns of anorexic people’s specific subjectivity. We seek to identify, in a first-person perspective, the core vulnerability features of anorexic existence, beyond the dimension of food alone. The identification of a psychopathological structure results in a better understanding of Jeanne’s clinical situation and helps formulate psychotherapeutic and prophylactic recommendations. We suggest that so-called “denial” is a psychological mechanism that should be reconsidered. Denial is not a mechanism pertaining to anorexic subjects alone, but is also a process encountered both in the patient’s family and in the therapeutic environment. Anorexic denial is based on anosognosia and the refusal to see one’s own thinness, while other people’s denial consists in a widespread inability to perceive the altruism and intersubjective problematic on which the existence of an anorexic subject fundamentally depends. [less ▲]

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See detailAgent-based Identification and Control of Voltage Emergency Situations
Robitzky, Lena; Weckesser, Tilman; Häger, Ulf et al

in IET Generation, Transmission & Distribution (in press)

Changing dynamics of power systems caused by the migration from conventional to distributed energy sources increase the risk of blackouts due to voltage instability, especially in case of unforeseen ... [more ▼]

Changing dynamics of power systems caused by the migration from conventional to distributed energy sources increase the risk of blackouts due to voltage instability, especially in case of unforeseen network conditions (e.g., (N-k)-cases). To enable a both secure and efficient power supply, novel monitoring and emergency control systems for the identification of voltage emergency situations as well as the execution of control actions are required that react reliably in due time and adaptively in case of changing network situations. This paper presents a distributed agent-based approach to counteract voltage instability that is based solely on local measurements and limited inter-agent communication. Distributed agents located at substations in the (sub-)transmission network monitor distribution and transmission voltages as well as load tap changer positions and are able to autonomously curtail load in case system stability is endangered. The applicability of the approach is demonstrated in a co-simulation environment interfacing the multi-agent system with a dynamic power system simulation. The presented approach allows for an early detection of voltage instability as well as a coordinated execution of available control actions. [less ▲]

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See detailDifferential contributions of default and dorsal attention networks to remembering thoughts and external stimuli from real-life events
Stawarczyk, David ULiege; Jeunehomme, Olivier ULiege; D'Argembeau, Arnaud ULiege

in Cerebral Cortex (in press)

Episodic memories are typically composed of perceptual information derived from the external environment and representations of internal states (e.g., one’s thoughts during prior episodes). To date ... [more ▼]

Episodic memories are typically composed of perceptual information derived from the external environment and representations of internal states (e.g., one’s thoughts during prior episodes). To date, however, research has mostly focused on the remembrance of external stimuli, such that little is known about how internal mentation is represented within episodic memory. In the present fMRI study, we examined the neural correlates of these two components of episodic memories using a novel method of cuing memories from photographs taken during real-life events. We found that, compared to corresponding semantic memory tasks, memories for internal thoughts and external elements were associated with activity in brain areas supporting episodic recollection. Most importantly, however, the two kinds of memories also showed differential activation in large-scale brain networks: the remembrance of external elements was associated with greater activity in the dorsal attention network, whereas memories of internal thoughts mainly recruited default network areas. These findings shed new light on the representation of internal and external aspects of prior experience within episodic memory. The default network may contribute to the reinstatement of thoughts experienced during past events, whereas the dorsal attention network may support the allocation of attention to visuo-spatial features within episodic memory representations. [less ▲]

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See detailBeliefs in the population about cracking sounds produced during spinal manipulation
Demoulin, Christophe ULiege; Baeri, Damien; TOUSSAINT, Geoffrey ULiege et al

in Joint Bone Spine (in press)

Objectives: To examine beliefs about cracking sounds heard during highvelocity lowamplitude (HVLA) thrust spinal manipulation in individuals with and without personal experience of this technique. Methods ... [more ▼]

Objectives: To examine beliefs about cracking sounds heard during highvelocity lowamplitude (HVLA) thrust spinal manipulation in individuals with and without personal experience of this technique. Methods: We included 100 individuals. Among them, 60 had no history of spinal manipulation, including 40whowereasymptomatic with or without a past history of spinal pain and 20whohad nonspecific spinal pain. The remaining 40 patients had a history of spinal manipulation;amongthem, 20 were asymptomatic and 20 had spinal pain. Participants attended a oneonone interview during which they completed a questionnaire about their history of spinal manipulation and their beliefs regarding sounds heard during spinal manipulation. Results: Mean age was 43.5±15.4 years. The sounds were ascribed to vertebral repositioning by 49% of participants and to friction between two vertebras by 23% of participants; only 9% of participants correctly ascribed the sound to the release of gas. The sound was mistakenly considered to indicate successful spinal manipulation by 40% of participants. No differences in beliefs were found between the groups with and without a history of spinal manipulation. Conclusions: Certain beliefs have documented adverse effects. This study showed a high prevalence of unfounded beliefs regarding spinal manipulation. These beliefs deserve greater attention from healthcare providers, particularly those who practice spinal manipulation. [less ▲]

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See detailRemapping Australia: Murray Bail's New Topographies of the Self in the Notebooks
Herbillon, Marie ULiege

in Commonwealth : Essays and Studies (in press), 40(1),

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See detailCassava post-harvest physiological deterioration: From triggers to symptoms
Zainuddin, Ima; Fathoni, Ahmad; Sudarmonowati, Enny et al

in Postharvest Biology and Technology (in press)

The production of cassava, the most important staple root crop in the world, is constrained by the short shelf life of the cassava storage roots that are undergoing post-harvest physiological ... [more ▼]

The production of cassava, the most important staple root crop in the world, is constrained by the short shelf life of the cassava storage roots that are undergoing post-harvest physiological deterioration (PPD) shortly after harvest. PPD reduces starch quality and renders the roots unpalatable and unmarketable. PPD is a complex process involving enzymatic stress responses to wounding, changes in gene expression and protein synthesis as well as accumulation of secondary metabolites. PPD can be strongly influenced by environmental factors making the identification of genotypes with delayed PPD trait difficult. In the present review, we propose an integrative presentation of PPD phenomenon based on a comprehensive analysis of several key PPD studies. We discuss recent progress in the standardization of methods to assess and score PPD tolerance in cassava roots. Traditional and improved storage techniques to extend cassava shelf-life are presented and prospects of transgenic approaches to delay PPD are discussed. [less ▲]

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See detailComprehensive Ion Mobility Calibration: Poly(ethylene oxide) Polymer Calibrants and General Strategies
Haler, Jean ULiege; Kune, Christopher ULiege; Massonnet, Philippe ULiege et al

in Analytical Chemistry (in press)

Ion Mobility (IM) is now a well-established and fast analytical technique. The IM hardware is constantly being improved, especially in terms of the resolving power. The Drift Tube (DTIMS), the Traveling ... [more ▼]

Ion Mobility (IM) is now a well-established and fast analytical technique. The IM hardware is constantly being improved, especially in terms of the resolving power. The Drift Tube (DTIMS), the Traveling Wave (TWIMS), and the Trapped Ion Mobility Spectrometry (TIMS) coupled to mass spectrometry are used to determine the Collision Cross-Sections (CCS) of ions. In analytical chemistry, the CCS is approached as a descriptor for ion identification and it is also used in physical chemistry for 3D structure elucidation with computational chemistry support. The CCS is a physical descriptor extracted from the reduced mobility (K0) measurements obtainable only from the DTIMS. TWIMS and TIMS routinely require a calibration procedure to convert measured physical quantities (drift time for TWIMS and elution voltage for TIMS) into CCS values. This calibration is a critical step to allow inter-instrument comparisons. The previous calibrating substances lead to large prediction bands and introduced rather large uncertainties during the CCS determination. In this paper, we introduce a new IM calibrant (CCS and K0) using singly charged sodium adducts of poly(ethylene oxide) monomethyl ether (CH3O-PEO-H) for positive ionization in both helium and nitrogen as drift gas. These singly charged calibrating ions make it possible to determine the CCS/K0 of ions having higher charge states. The fitted calibration plots exhibit larger coverage with less data scattering and significantly improved prediction bands and uncertainties. The reasons for the improved CCS/K0 accuracy, advantages and limitations of the calibration procedures are also discussed. A generalized IM calibration strategy is suggested. [less ▲]

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See detailTocopherols and polyphenols in pumpkin seed oil are moderately affected by industrially relevant roasting conditions
Van Hoed; Araujo Sampaio; Felkner et al

in European Journal of Lipid Science and Technology [=EJLST] (in press)

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See detailHyper-réflexivité et perspective en première personne : un apport décisif de la psychopathologie phénoménologique contemporaine à la compréhension de la schizophrénie
Englebert, Jérôme ULiege; Stanghellini, Giovanni; Valentiny, Caroline et al

in Evolution Psychiatrique (in press)

Objectives: This paper aims to summarize the hypothesis, which originates in the field of phenomenological psychopathology, of schizophrenic hyperreflexivity, and to discuss the methodological context ... [more ▼]

Objectives: This paper aims to summarize the hypothesis, which originates in the field of phenomenological psychopathology, of schizophrenic hyperreflexivity, and to discuss the methodological context enabling these highly subjective manifestations to emerge. Starting from the seminal hypothesis developed by contemporary psychopathology, that the schizophrenic patients appear to experience a consciousness that finds itself being forced to question phenomena which should be intuitively self-evident, the idea of this present paper is to complete the usual interpretation of schizophrenia as deficit by the hypothesis of an excess functioning of consciousness. Methods: First-person perspective is a qualitative approach completing third-person interpretation, traditional in the field of psychiatry – which consists in the attribution, from an external position, of clinical signs noted independently of the perception expressed by the patient. This first-person perspective focuses on the subjective experience expressed by the individual. To understand schizophrenia according to this perspective, the words of several schizophrenic patients have been collected as part of a clinical device. We used the EASE scale (Examination of Anomalous Self-Experience) with this aim in mind. This scale offers a phenomenologically oriented semi-structured exploration of a set of difficulties revealing anomalies of subjective experience, considered as troubles of self-awareness. EASE has been developed on the basis of self-descriptions by patients suffering from schizophrenic spectrum troubles. This tool allows the co-construction of a language between patient and clinician, focused on the patient’s particular experience and the unique phenomena he endures. Results: Besides the hyperreflexivity phenomena, the qualitative analysis of collected descriptions highlight two important features of schizophrenic being-in-the-world. First a problem of common sense, which addresses the issue of intersubjectivity and the opportunity, for schizophrenic patients, to share a social world. Then the existence of an intercorporeality trouble, since the schizophrenic hyperreflexivity experiences are accompanied by a loss of “common body”, body being the scene where intersubjectivity is performed. Employing EASE, and the ensuing first-person perspective, is relevant in a psychotherapeutic approach; on one hand in the process of acknowledgement of the disease (which has to be made by the patient as well as by the clinician), on the other hand in the communication with families of schizophrenic patients. Conclusions: The phenomenological interpretation offered by the application of a first-person perspective in the understanding of schizophrenic patients experience, as well as the interest showed in the hyperreflexivity phenomenon, suggest an outlook of schizophrenia which isn’t reduced to a deficit interpretation anymore (without denying the latter), and which uncovers not a weakening, but a surprising intensification of consciousness. [less ▲]

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See detailDépression unipolaire et personnalité prémorbide : version francophone du Criteria for Typus Melancholicus
Englebert, Jérôme ULiege; Stanghellini, Giovanni; Calderazzo, Déborah et al

in Psychologie Française (in press)

The Typus Melancholicus (TM) is a pre-melancholic personality structure, defined by Tellenbach and Kraus and characterized by the orderliness, conscientiousness, norm orientation and intolerance of ... [more ▼]

The Typus Melancholicus (TM) is a pre-melancholic personality structure, defined by Tellenbach and Kraus and characterized by the orderliness, conscientiousness, norm orientation and intolerance of ambiguity. This study aims to discriminate the existence of a subgroup TM, among a unipolar depressive population. In order to prove the existence of this subgroup, we translated and administrated the Criteria for Typus Melancholicus (CTM) to a sample of 20 unipolar patients and 20 control participants. The research hypothesis was to find a similar proportion to the one observed in the literature (50% of TM in the unipolar sample). The results demonstrate, as expected, that half of the unipolar sample belongs to a homogeneous subgroup that displays the TM features. Furthermore, no control subjects displays the TM features. Those results suggest that the TM features design a coherent and typical psychopathological structure that can be found in an important proportion of unipolar depressive population. Our study identifies and confirms the existence of a distinct heterogeneity (TM/noTM) inside the unipolar group. This distinction opens the door to some important perspectives in terms of therapy. [less ▲]

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See detailHydraulic determination of dam releases to generate warning waves in a mountain stream: performance of an analytical kinematic wave model
Stilmant, Frédéric; Pirotton, Michel ULiege; Archambeau, Pierre ULiege et al

in Journal of Hydraulic Engineering (in press)

In this case study, we study the generation of warning waves with prescribed characteristics in a mountain stream. We determine which dam release will generate the desired warning wave. We solve this ... [more ▼]

In this case study, we study the generation of warning waves with prescribed characteristics in a mountain stream. We determine which dam release will generate the desired warning wave. We solve this inverse problem following a two-model approach. An analytical kinematic model is used for a preliminary design of the dam release and a detailed two-dimensional (2D) fully dynamic model is used to converge to the final solution. Although the presented case study is far from an idealized academic case, the analytical model performs well and, beyond its role for preliminary design, turns out to be of prime interest for both understanding and discussing the results of the detailed 2D model. The complex interactions between the release hydrograph, the geometry of the river and the friction formula are brought to light by the analytical model, which highlights the complementarity of both models and the usefulness of such a two-model approach. [less ▲]

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See detailAssociation between self-perception of aging, view of cancer and health of older patients in oncology: A one-year longitudinal study
Schroyen, Sarah ULiege; Missotten, Pierre ULiege; JERUSALEM, Guy ULiege et al

in BMC Cancer (in press)

Background: Identifying older people affected by cancer who are more at risk of negative health outcomes is a major issue in health initiatives focusing on medical effectiveness. In this regard ... [more ▼]

Background: Identifying older people affected by cancer who are more at risk of negative health outcomes is a major issue in health initiatives focusing on medical effectiveness. In this regard, psychological risk factors such as patients’ perception of their own aging and cancer could be used as indicators to improve customization of cancer care. We hypothesize that more negative self-perception of aging (SPA) and view of cancer could be linked to worse physical and mental health outcomes in cancer patients. Methods: 101 patients diagnosed with cancer (breast, gynecological, lung or hematological) were followed for one year. They were evaluated on four occasions (baseline, 3, 6 and 12 months after the baseline). Their SPA, view of cancer and health (physical and mental) were assessed at each time of evaluation. Results: Negative SPA and/or view of cancer at baseline are associated with negative evolution of patients’ physical and mental health. Moreover, when the evolution of SPA and cancer view were taken into account, these two stigmas are still linked with the evolution of mental health. In comparison, only a negative evolution of SPA was linked to worse physical health outcomes. Conclusions: Such results indicate that SPA and view of cancer could be used as markers of vulnerability in older people with cancer. [less ▲]

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See detailPermutations and negative beta-shifts
Charlier, Emilie ULiege; Steiner, Wolfgang

in International Journal of Foundations of Computer Science (in press)

Elizalde (2011) characterized which permutations can be obtained by ordering consecutive elements in the trajectories of (positive) beta-transformations and beta-shifts. We prove similar results for ... [more ▼]

Elizalde (2011) characterized which permutations can be obtained by ordering consecutive elements in the trajectories of (positive) beta-transformations and beta-shifts. We prove similar results for negative bases beta. [less ▲]

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See detailCommunication of healthcare professionals: is there ageism?
Schroyen, Sarah ULiege; Adam, Stéphane ULiege; Marquet, Manon ULiege et al

in European Journal of Cancer Care (in press)

Elderspeak is often used when talking to older individuals and is characterized by a slower and/or louder speech, a patronizing tone, etc. A part of the reason of such communication can be found in the ... [more ▼]

Elderspeak is often used when talking to older individuals and is characterized by a slower and/or louder speech, a patronizing tone, etc. A part of the reason of such communication can be found in the actual context of negative view of aging. However, the link between view of aging and elderspeak has never been objectively studied in oncology. Therefore, 40 healthcare professionals (physicians and medical students) record a podcast where they have to explain an endocrine therapy to two fictional patients (40 vs 70 years old). Results show that when participants explained the treatment to the older patient, they used shorter utterances and made more repetitions. They also evoked fewer side effects such as sexual issues. Moreover, reduction of length of utterances and of word-per-minute rate was observed for older patient when participants have a positive view of aging but for both patients when they have a negative view of aging. In conclusion, physicians and medical students used elderspeak when they explained a treatment to older patients. Participants with a more negative view of aging also unconsciously talked slower and made shorter utterances to a 40 year-old patient. [less ▲]

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See detailProtein folding at extreme temperatures: current issues
Feller, Georges ULiege

in Seminars in Cell & Developmental Biology (in press)

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See detailEntre mutation et métissage Co-construction d’une ethnographie émancipatrice et féministe
Vivas Romero, Maria ULiege

in Émulation Revue des Jeunes Chercheuses et chercheurs en sciences sociales (in press)

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See detailObjet et pratiques sémiotiques : quelques enjeux médiatiques du support photographique
Honba Honba, Cédric ULiege

in Signata. Annales des Sémiotiques = Annals of Semiotics (in press)

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See detailComic strips et papier glacé. Rétro-réflexivité et pseudo-sérialité dans Little Tommy Lost
Crucifix, Benoît ULiege

in Recherches en Communication (in press)

Cet article examine la place du comic strip au sein du roman graphique contemporain à travers l'analyse de Little Tommy Lost (2013) de l'auteur américain Cole Closser. La particularité de cette œuvre ... [more ▼]

Cet article examine la place du comic strip au sein du roman graphique contemporain à travers l'analyse de Little Tommy Lost (2013) de l'auteur américain Cole Closser. La particularité de cette œuvre tient en ce qu'elle se propose comme un pastiche rigoureux de divers comic strips des années 1920 et 1930, allant jusqu'à se faire passer pour une collection d'anciens strips oubliés puis redécouverts. Little Tommy Lost creuse donc une vague "rétro-réflexive" qui interroge la façon dont la bande dessinée peut remédier ses propres identités culturelles. Il s'agira de cerner les enjeux stylistiques, sériels, narratifs et culturels d'une telle remédiation rétro-réflexive. [less ▲]

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See detailBridging novelty and familiarity-based recognition memory: a matter of timing
Delhaye, Emma ULiege; Bastin, Christine ULiege; Moulin, Christopher et al

in Visual Cognition (in press)

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See detailThe Roles of Networks in Institutionalizing New Hybrid Organizational Forms: Insights from the European Renewable Energy Cooperative Network
Huybrechts, Benjamin ULiege; Haugh, Helen

in Organization Studies (in press)

Hybrid organizational forms combine values and practices from different institutional domains, rendering them difficult to fit neatly into the structures of extant organizational forms. Since the work ... [more ▼]

Hybrid organizational forms combine values and practices from different institutional domains, rendering them difficult to fit neatly into the structures of extant organizational forms. Since the work required to institutionalize a new hybrid organizational form may be beyond the resources and capabilities of individual organizations acting alone, we shift the focus to inter-organizational collective action. Using empirical data from a study of a European network of renewable energy cooperatives, we find that, in order to institutionalize the new hybrid organizational form, the network can contribute to overcome the legitimacy challenges inherent in organizational hybridity. In particular, the network builds field-level receptivity to institutional pluralism, collectively codifies the hybrid organizational form, and consolidates legitimation towards plural field-level audiences. In order to perform these institutionalization roles, the network itself becomes increasingly formalized and mobilizes mediating functions involving different types of resources, legitimacy and target audiences. The research advances knowledge of hybrid organizational forms and their collective institutionalization through inter-organizational networks. [less ▲]

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See detailVoice use among music theory teachers: A voice dosimetry and self-assessment study
Schiller, Isabel ULiege; Morsomme, Dominique ULiege; Remacle, Angélique ULiege

in Journal of Voice (in press)

Objectives: (1) To investigate music theory teachers’ professional and extra-professional vocal loading and background noise exposure, (2) to determine the correlation between vocal loading and background ... [more ▼]

Objectives: (1) To investigate music theory teachers’ professional and extra-professional vocal loading and background noise exposure, (2) to determine the correlation between vocal loading and background noise, and (3) to determine the correlation between vocal loading and self-evaluation data. Methods: Using voice dosimetry, 13 music theory teachers were monitored for one workweek. Parameters analysed were voice SPL, F0, phonation time, vocal loading index (VLI) and noise SPL. Spearman’s correlation was used to correlate vocal loading parameters (voice SPL, F0 and phonation time) and noise SPL. Each day, subjects self-assessed their voice using visual analogue scales. VLI and self-evaluation data were correlated using Spearman’s correlation. Results: Vocal loading parameters and noise SPL were significantly higher in the professional than in the extra-professional environment. Voice SPL, phonation time and females’ F0 correlated positively with noise SPL. VLI correlated with self-assessed voice quality, vocal fatigue and amount of singing and speaking voice produced. Conclusions: Teaching music theory is a profession with high vocal demands. More background noise is associated with increased vocal loading and may indirectly increase the risk for voice disorders. Correlations between VLI and self-assessments suggest that these teachers are well-aware of their vocal demands and feel their effect on voice quality and vocal fatigue. Visual analogue scales seem to represent a useful tool for subjective vocal loading assessment and associated symptoms in these professional voice users. [less ▲]

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See detailKIAA1199: a novel regulator of MEK/ERK-induced Schwann cell dedifferentiation
Boerboom, Angelique; Reusch, Céline ULiege; Pieltain, Alexandra ULiege et al

in Glia (in press)

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See detailUrethral intussusception following traumatic catheterization in a male cat
Broux, Olivier ULiege; Vangrinsven, Emilie ULiege; Etienne, Anne-Laure ULiege et al

in Canadian Veterinary Journal = Revue Vétérinaire Canadienne (in press)

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See detailIncreased antimicrobial resistance in a novel CMY-54 AmpC-type enzyme with a GluLeu217-218 insertion in the Ω-loop
Pérez-Llarena, Francisco José; Vázquez-Ucha, Juan Carlos; Kerff, Frédéric ULiege et al

in Microbial Drug Resistance : Mechanism, Epidemiology, & Disease (in press)

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See detailEndotracheal tube obstruction during endoscopy improves dynamic sliding hiatal hernia detection in dogs with brachycephalic syndrome
Broux, Olivier ULiege; Clercx, Cécile ULiege; Etienne, Anne-Laure ULiege et al

in Veterinary Surgery : The Official Journal of the American College of Veterinary Surgeons (in press)

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See detailSublime Gaps: the Absence of Closure in the Metaphysical Detective Story
Dechene, Antoine ULiege

in Sillages critiques (in press)

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See detailPsychological interventions influence patients' attitudes and beliefs about their chronic pain.
VANHAUDENHUYSE, Audrey ULiege; Gillet, Aline; MALAISE, Nicole ULiege et al

in Journal of Traditional and Complementary Medicine (in press)

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See detailEffect of different parameters on composition of volatile components of Myristica fragrans seeds extracted by hydrodistillation assisted by microwave and head-space solid-phase microextraction
Bouchachia, C; Benkaci-Ali, F; Eppe, Gauthier ULiege et al

in Journal of Essential Oil Research (in press)

Hydrodistillation assisted by microwave (HDAM) and Head space solid phase micro-extraction (HSSPME) of Myristica fragrans houtt (MF) were investigated. A kinetic study was performed for MF seeds using two ... [more ▼]

Hydrodistillation assisted by microwave (HDAM) and Head space solid phase micro-extraction (HSSPME) of Myristica fragrans houtt (MF) were investigated. A kinetic study was performed for MF seeds using two techniques (HDAM: Hydrodistillation assisted by microwave and SDAM: steam distillation assisted by microwave). The effect of the cryogenic grinding (CG) showed differences in yields and composition of volatile oils compared to the simple grinding (SG). HDAM–SG (3.4%) and SDAM–SG (2.55%) allowed extraction of substantial amounts of volatile oils in less time compared with HDAM–CG (4.75%) and SDAM–CG (3.8%). The kinetic study (differential and accumulated yields) of essential oil extraction was quantitatively and qualitatively performed showing a significant variation of composition with the extraction time, especially for accumulated yields such as sabinene (31.48–38.78%), α-pinene (12.74–14.09%) and β-pinene (10.01–12.11%). Similarly, the HS-SPME–GC–MS analysis showed also a significant variation of MF seeds volatile composition according some parameters as the type of fibre coating (PDMS: Polydimethylsiloxane and PDMS– DVB: Polydimethylsiloxane divenylbenzene), particle size, grinding mode and the mass used. The chemical groups (monoterpenoids, aliphatic and aromatic alcohols and esters) showed specific behaviour in SPME analysis. SPME sampling parameters were optimized for these components. [less ▲]

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See detail10Nous : oser la lexicographie participative
Steffens, Marie ULiege; Beyer, Thomas ULiege

in Les Essentiels de Maqalid (in press), (8),

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See detailSystem-based approaches for structural optimization of flexible mechanisms
Tromme, Emmanuel; Held, Alexander; Duysinx, Pierre ULiege et al

in Archives of Computational Methods in Engineering (in press)

This paper reviews the state-of-the-art methods to perform structural optimization of flexible mechanisms. These methods are based on a system-based approach, i.e. the formulation of the design problem ... [more ▼]

This paper reviews the state-of-the-art methods to perform structural optimization of flexible mechanisms. These methods are based on a system-based approach, i.e. the formulation of the design problem incorporates the time response of the mechanism that is obtained from a dynamic simulation of the flexible multibody system. The system-based approach aims at considering as precisely as possible the effects of nonlinear dynamic loading under various operating conditions. Also, the optimization process enhances most existing studies which are limited to (quasi-) static or frequency domain loading conditions. This paper briefly introduces flexible multibody system dynamics and structural optimization techniques. Afterwards, the two main methods, named the weakly and the fully coupled methods, that couple both disciplines are presented in details and the influence of the multibody system formalism is analyzed. The advantages and drawbacks of both methods are discussed and future possible research areas are mentioned. [less ▲]

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See detailCompte rendu de G. TOUSSAINT, Kreuz und Knochen. Reliquien zur Zeit der Kreuzzüge, Berlin, 2011.
George, Philippe ULiege

in Cahiers de Civilisation Médiévale (in press)

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See detailComplications of paediatric parenteral nutrition
Decsi, T; Hartman, C; Simchowitz, V et al

in Clinical Nutrition (in press)

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See detailBrentano's Mind: Unity Without Simplicity
Dewalque, Arnaud ULiege

in Rivista di Filosofia (in press)

This paper offers a reconstruction of Franz Brentano’s mereological solution to the problem of the unity of consciousness and explores some implications of this solution for the ontology of the mind. In ... [more ▼]

This paper offers a reconstruction of Franz Brentano’s mereological solution to the problem of the unity of consciousness and explores some implications of this solution for the ontology of the mind. In section 1 I sketch Brentano’s ontological distinctions between things, collectives, and divisives. In section 2 I present Brentano’s mereological solution and in section 3 I review his main pro-arguments. Eventually, in section 4 I consider some Jamesian objections to the mereological approach. I argue the notion of ‘mental parts’ can be given a rather innocuous meaning by being conceived of as the expression of conceptual distinctions grounded in similarity and contrast relations between total mental phenomena. [less ▲]

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See detailTemporal grouping effects in musical short-term memory
Gorin, Simon ULiege; Mengal, Pierre; Majerus, Steve ULiege

in Memory (in press)

Recent theoretical accounts of verbal and visuo-spatial short-term memory (STM) have proposed the existence of domain-general mechanisms for the maintenance of serial order information. These accounts are ... [more ▼]

Recent theoretical accounts of verbal and visuo-spatial short-term memory (STM) have proposed the existence of domain-general mechanisms for the maintenance of serial order information. These accounts are based on the observation of similar behavioural effects across several modalities, such as temporal grouping effects. Across two experiments, the present study aimed at extending these findings, by exploring a STM modality that has received little interest so far, STM for musical information. Given its inherent rhythmic, temporal and serial organisation, the musical domain is of interest for investigating serial order STM processes such as temporal grouping. In Experiment 1, the data did not allow to determine the presence or the absence of temporal grouping effects. In Experiment 2, we observed that temporal grouping of tone sequences during encoding improves short-term recognition for serially presented probe tones. Furthermore, the serial position curves included micro-primacy and micro-recency effects, which are the hallmark characteristic of temporal grouping. Our results suggest that the encoding of serial order information in musical STM may be supported by temporal positional coding mechanisms similar to those reported in the verbal domain. [less ▲]

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See detailL’activité éditoriale comme démarche de représentation de la connaissance: l’exemple de la ponctuation médiévale
Mazziotta, Nicolas ULiege

in Diachroniques: Revue de linguistique française diachronique (in press)

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See detailLe trouble bipolaire de l’adolescent : Comment favoriser un diagnostic et une prise en charge précoce ?
Simon, Michaël ULiege

in Acta Psychiatrica Belgica (in press)

In half the cases, bipolar disorder begins before adulthood. The usual long delay between its onset and the establishment of proper treatment has adverse effects on the developing brain. The prognosis of ... [more ▼]

In half the cases, bipolar disorder begins before adulthood. The usual long delay between its onset and the establishment of proper treatment has adverse effects on the developing brain. The prognosis of the disease could be improved by early diagnosis and treatment. From the case of a manic episode in a 16 year old teenager, we discuss the characteristics of manic prodromes, their diagnostic criteria and therapeutic means. We then criticize the concept of diagnosis in the stage of prodromal symptoms. We propose to dispense with the need for diagnosis and promote access to mental health care to any person with mental suffering. [less ▲]

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See detailFinds from an end-first century’s context at Piano della Civita (Artena, RM): preliminary results
Dienst, Simon ULiege; Motta, Lucie ULiege

in Orizzonti. Rassegna di archeologia (in press), XIX

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See detailThe effect of spaceflight and microgravity on the human brain
Van Ombergen, Angelique; Demertzi, Athina ULiege; Tomilovskaya et al

in Journal of Neurology (in press)

Microgravity, confinement, isolation, and immobilization are just some of the features astronauts have to cope with during space missions. Consequently, long-duration space travel can have detrimental ... [more ▼]

Microgravity, confinement, isolation, and immobilization are just some of the features astronauts have to cope with during space missions. Consequently, long-duration space travel can have detrimental effects on human physiology. Although research has focused on the cardiovascular and musculoskeletal system in particular, the exact impact of spaceflight on the human central nervous system remains to be determined. Previous studies have reported psychological problems, cephalic fluid shifts, neurovestibular problems, and cognitive alterations, but there is paucity in the knowledge of the underlying neural substrates. Previous space analogue studies and preliminary spaceflight studies have shown an involvement of the cerebellum, cortical sensorimotor, and somatosensory areas and the vestibular pathways. Extending this knowledge is crucial, especially in view of long-duration interplanetary missions (e.g., Mars missions) and space tourism. In addition, the acquired insight could be relevant for vestibular patients, patients with neurodegenerative disorders, as well as the elderly population, coping with multisensory deficit syndromes, immobilization, and inactivity. [less ▲]

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See detailCalcium, phosphorus and magnesium in Paediatric Parenteral Nutrition
Fewtrell, mary; Goulet, Olivier; Mihatsch, Walter et al

in Clinical Nutrition (in press)

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See detailIntravenous lipid emulsions in paediatric patients
Lapillonne, A; Didler Mis, N; Goulet et al

in Clinical Nutrition (in press)

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See detail'Les orphelins sur la tombe de leur mère' at the Crossing with Flemish Tradition
Peere, Isabelle ULiege

in B·A·S·I·S: Ballads and Songs - International Studies (in press)

The study proposes a comparative analysis of the French-language and Flemish/Dutch versions of the international ballad deriving from the Danish 'Moderen under Mulde' (Dgf 89), and on this basis ... [more ▼]

The study proposes a comparative analysis of the French-language and Flemish/Dutch versions of the international ballad deriving from the Danish 'Moderen under Mulde' (Dgf 89), and on this basis identifies three French-language texts recorded in North-east France and Wallonia yet showing closer affinities to the neighbouring Flemish tradition. In the light of both textual traditions, their unilateral adoption of Flemish motifs and their enhancing effect suggests deliberate selection rather than mere geographical proximity or bilingualism as explanation for their hybridization. [less ▲]

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See detailCytotoxic T-lymphocyte-associated protein 4-Ig effectively controls immune activation and inflammatory disease in a novel murine model of leaky severe combined immunodeficiency
Humblet-Baron, Stephanie; Schönefeldt, Susan; Garcia-Perez, Josselyn E et al

in Journal of Allergy and Clinical Immunology (The) (in press)

Background: Severe combined immunodeficiency (SCID) can be caused by loss-of-function mutations in genes involved in the DNA recombination machinery, such as RAG1, RAG2 or DCLRE1C. Defective DNA ... [more ▼]

Background: Severe combined immunodeficiency (SCID) can be caused by loss-of-function mutations in genes involved in the DNA recombination machinery, such as RAG1, RAG2 or DCLRE1C. Defective DNA recombination causes a developmental block in T cells and B cells, resulting in high susceptibility to infections. Hypomorphic mutations in the same genes can also give a partial loss of T cells, in a spectrum including leaky SCID (LS) and Omenn syndrome (OS). These patients not only develop life-threatening infections due to immunodeficiency, but also develop inflammatory/autoimmune conditions due to the presence of autoreactive T cells. Objective: We sought to develop a preclinical model that fully recapitulates the symptoms of LS/OS patients including a model for testing therapeutic intervention. Methods: We generated a novel mutant mouse (Dclre1c leaky) that develops a LS phenotype. Mice were monitored for diseases and immune phenotype and immune function were evaluated using flow cytometry, ELISA and histology. Results: Dclre1c leaky mice present with a complete blockade of B cell differentiation, with a leaky block in T cell differentiation resulting in an oligoclonal TCR repertoire and enhanced cytokine secretion. Dclre1c leaky mice also developed inflammatory symptoms including wasting, dermatitis, colitis, hypereosinophilia and high IgE levels. Development of a preclinical murine model for LS allowed the testing of potential treatment, with administration of CTLA4-Ig reducing disease symptoms and immunological disturbance, resulting in increased survival. Conclusion: These data suggest that CTLA4-Ig should be evaluated as a potential treatment of inflammatory symptoms in LS and OS patients. [less ▲]

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See detail"'Vive la rose' in Newfoundland: from Alien to Emblem'
Peere, Isabelle ULiege

in B·A·S·I·S: Ballads and Songs - International Studies (in press)

This paper traces the song in European tradition through to its ‘revival’ in the 1960s. It analyses Emile’ Benoît's textual and musical recreation of it in the light of my own and other fieldworkers’ ... [more ▼]

This paper traces the song in European tradition through to its ‘revival’ in the 1960s. It analyses Emile’ Benoît's textual and musical recreation of it in the light of my own and other fieldworkers’ accounts of his personality, ethos and creative talent in tradition. The study traces the song's course and progress in Newfoundland, following in the steps of French-Canadian ethno-historian Ronald Labelle’s suggestion that ‘Vive la Rose’ has come to function as identity emblem for Newfoundland’s francophone minority – and even as its representative throughout French-Canada and especially Acadia. [less ▲]

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See detailNote a Jacopino del Conte e approfondimenti sulla sua attività giovanile
Geremicca, Antonio ULiege

in Proporzioni. Annali della Fondazione Roberto Longhi (in press)

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See detailPsychopathologie et monde social : les limites de l'empathie et de la sympathie
Englebert, Jérôme ULiege

in Philosophie (in press)

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See detailThe use of platelet-rich plasma (PRP) to treat chronic tendinopathies: a technical analysis
Kaux, Jean-François ULiege; Emonds-Alt, Thibault ULiege

in Platelets (in press)

Platelet-rich plasma (PRP) is blood plasma with a high concentration of autologous platelets which constitute an immense reservoir of growth factors. The clinical use of PRP is widespread in various ... [more ▼]

Platelet-rich plasma (PRP) is blood plasma with a high concentration of autologous platelets which constitute an immense reservoir of growth factors. The clinical use of PRP is widespread in various medical applications. Although highly popular with athletes, the use of PRP for the treatment of tendinopathies remains scientifically controversial, particularly due to the diversity of products that go by the name of “PRP.” To optimize its use, it is important to look at the various stages of obtaining PRP. In this literature review, we take a closer look at eight parameters which may influence the quality of PRP: 1) anticoagulants used to preserve the best platelet function, 2) the speed of centrifugation used to extract the platelets, 3) the platelet concentrations obtained, 4) the impact of the concentration of red and while blood cells on PRP actions, 5) platelet activators encouraging platelet degranulation and, hence, the release of growth factors, and 6) the use or nonuse of local anesthetics when carrying out infiltration. In addition to these parameters, it may be interesting to analyze other variables such as 7) the use of ultrasound guidance during the injection with a view to determining the influence they have on potential recovery. [less ▲]

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See detailInvestigation on Water Productivity of Winter Wheat Based on MODIS and SEBAL in the Huang-Huai-Hai Plain, China
Yang, Jian-ying; HUO, Zhi-guo; Wu, Ding-rong et al

in Chinese Journal of Agrometeorology (in press)

Understanding how the productivity of water can be increased is widely accepted to be a high priority where water resources are currently scarce and/or over-exploited in China. As the primary data source ... [more ▼]

Understanding how the productivity of water can be increased is widely accepted to be a high priority where water resources are currently scarce and/or over-exploited in China. As the primary data source, MODIS remote sensing, statistics, meteorological data, crop growth period data and ground truth-data from Jan. 2011 to Dec. 2012 were used in actual evapotranspiration estimation, yields rasterizing, and water productivity calculation for winter wheat in the Huang-Huai-Hai Plain (3H Plain). The statistical data were synthesized to calculate district-state-level land productivity, which is then further extrapolated to pixel-level values using a MODIS NDVI image, based on a crop dominance map. Spatial variation of crop water productivity was investigated in order to reveal the key factors of crop water productivity. In addition, the relationship between water productivity and actual evapotranspiration and in subsequence yield for winter wheat was discussed in 3H Plain. The main results indicated that the SEBAL is suitable for estimating evapotranspiration in winter wheat based on the comparation between evapotranspiration measured by Yucheng (in Shandong province). The regional average value of water productivity for winter wheat was detected to be 1.21kg·m-3, with the higher value in Beijing, Tianjin, north part of Shandong province and south part of Hebei province. The pronounced relationship of spatial correlation of the yield and water productivity for winter wheat indicated that the increasing yield governed the increment of water productivity for winter wheat in the coastal land-farming-fishing area (zone1), low plain-hydropenia irrigable land and dry land zone (zone2) and basin- irrigable land and dry land (zone5). The increasing water productivity for winter wheat was recognized to be controlled by rather the increment of yield than the reduction of actual evapotranspiration for winter wheat in the piedmont plain-irrigable land (zone2). Whereas, the pronounced relationship of negative correlation of water productivity and actual evapotranspiration for winter wheat described that only the reduction of actual evapotranspiration was responsible for the increment of water productivity for winter wheat in hill-wet hot paddy-paddy field (zone6). The results is expected to provide a basis information for agricultural water management, improvement of crop water productivity and choice of adaptive mechanism under climate change in Huang-Huai-Hai plain. [less ▲]

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