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Prêtre, "Kosmos et kosmema. Les offrandes de parure dans les inventaires déliants"Veymiers, Richard in Revue archéologique (in press)Detailed reference viewed: 31 (2 ULg) Arsinoe II come dea attraverso le sue epiclesi cultualiCaneva, Stefano in Athenaeum : Studii Periodici di Letteratura e Storia (in press), 103(1), 95-122Dopo una introduzione storica e storiografica sul significato dei culti regali ellenistici, l’intervento esamina alcuni dei nomi divini attribuiti ad Arsinoe II nelle fonti letterarie e documentarie, con ... [more ▼]Dopo una introduzione storica e storiografica sul significato dei culti regali ellenistici, l’intervento esamina alcuni dei nomi divini attribuiti ad Arsinoe II nelle fonti letterarie e documentarie, con l’eccezione dell’epiclesi esclusiva Philadelphos. Scopo della ricerca è 1) una valutazione delle strategie di inserimento della nuova dea nel pantheon tradizionale; 2) una riflessione sull’autoconsapevolezza degli antichi in relazione alla propria tradizione religiosa, per come essa si manifesta attraverso l’oculata manipolazione di un elemento essenziale nella definizione della divinità, qual è il nome divino. Un’Appendice elenca, in tre tabelle, tutte le denominazioni greche di Arsinoe II (esclusa Philadelphos), fornendo indicazioni sulla fonte, la sua collocazione spaziale e temporale e sulla divinità tradizionale di riferimento. [less ▲]Detailed reference viewed: 68 (9 ULg) Étude des contraintes mécaniques locomotrices chez le chevalNoble, Prisca ; Collin, Bernard ; Denoix, Jean-Marie et alin Annales de Médecine Vétérinaire (in press)In locomotor biomechanics, three high groups of contraints are commonly encountared : pressure, traction and torsion. In supra-maximal conditions, all of these contraints would be responsible of some ... [more ▼]In locomotor biomechanics, three high groups of contraints are commonly encountared : pressure, traction and torsion. In supra-maximal conditions, all of these contraints would be responsible of some equine diseased locomotor systems. In order to understand better the contraints in the equine locomotor dynamics, some investigations have been carried out. Moreover, some measurement methods, based on the mechanics of Newton, have been performed. This review shows the different measurement techniques and introduces the mechanical basis that are compulsory for the understanding of the equine locomotor apparatus functioning. [less ▲]Detailed reference viewed: 169 (34 ULg) Ignorance et maîtrise de la bête. Lefort critique de l'éducation "humaniste".Mancuso, Eva in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)Detailed reference viewed: 19 (4 ULg) Contribution à un lexique épigraphique: "deltographéma"Famerie, Etienne in Zeitschrift für Papyrologie und Epigraphik (in press)Detailed reference viewed: 42 (11 ULg) Employee Emotional Competence: Construct Conceptualization and Validation of a Customer-Based MeasureDelcourt, Cécile ; Gremler, Dwayne; van Riel, Allard et alin Journal of Service Research (in press)Customers often experience intense emotions during service encounters. Their perceptions of how well contact employees demonstrate emotional competence in emotionally charged service encounters can affect ... [more ▼]Customers often experience intense emotions during service encounters. Their perceptions of how well contact employees demonstrate emotional competence in emotionally charged service encounters can affect their service evaluations and loyalty intentions. Previous studies examining employees’ potential to behave in emotionally competent ways (i.e., employee emotional intelligence [EEI]) have used self- or supervisor-reported scales to predict customer outcomes, presenting EEI as stable and independent of the context. However, service firms should be more concerned with the actual display of emotionally competent behaviors by employees (employee emotional competence [EEC]), because employee behaviors vary across encounters. Moreover, a customer perspective of EEC is useful as customer perceptions of employee performance are crucial predictors of satisfaction and loyalty. Therefore, this study proposes a conceptualization and operationalization of EEC in a service encounter context. On the basis of a comprehensive literature review and in-depth interviews, the authors develop a scale to capture customer-perceived EEC, defined as an employee’s competence in perceiving, understanding, and regulating customer emotions during a discrete service encounter. The scale achieves good reliability and validity. Researchers can use it to explore the role of EEC in service contexts; managers can employ the scale to diagnose EEC and improve customers’ service encounter experiences. [less ▲]Detailed reference viewed: 12 (1 ULg) A probabilistic model for predicting the uncertainties of the humid stiction phenomenon on hard materialsHoang Truong, Vinh ; Wu, Ling ; Paquay, Stéphane et alin Journal of Computational & Applied Mathematics (in press)Stiction is a major failure in microelectromechanical system (MEMS) devices in which two contacting surfaces can remain stuck together because of the adhesive forces. Due to the difference between the ... [more ▼]Stiction is a major failure in microelectromechanical system (MEMS) devices in which two contacting surfaces can remain stuck together because of the adhesive forces. Due to the difference between the surfaces roughness and the adhesive force range, the real contact areas are usually smaller than the apparent one, resulting in a scatter in the adhesive forces. Consequently, the stiction is an uncertain phenomenon. In this work, we develop a probabilistic model to predict the uncertainties of stiction due to the capillary forces acting on stiff materials. This model contains two levels: at the deterministic level, the model can predict the pull-out adhesive contact forces for a given surface topology; at the probabilistic level, the model generates independent identically distributed surfaces on which the deterministic solution can be applied to evaluate the uncertainties related to the stiction phenomenon. [less ▲]Detailed reference viewed: 95 (46 ULg) Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice.Harvey, N. C.; Gluer, C. C.; Binkley, N. et alin Bone (in press)Trabecular bone score (TBS) is a recently-developed analytical tool that performs novel grey-level texture measurements on lumbar spine dual X-ray absorptiometry (DXA) images, and thereby captures ... [more ▼]Trabecular bone score (TBS) is a recently-developed analytical tool that performs novel grey-level texture measurements on lumbar spine dual X-ray absorptiometry (DXA) images, and thereby captures information relating to trabecular microarchitecture. In order for TBS to usefully add to bone mineral density (BMD) and clinical risk factors in osteoporosis risk stratification, it must be independently associated with fracture risk, readily obtainable, and ideally, present a risk which is amenable to osteoporosis treatment. This paper summarizes a review of the scientific literature performed by a Working Group of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis. Low TBS is consistently associated with an increase in both prevalent and incident fractures that is partly independent of both clinical risk factors and areal BMD (aBMD) at the lumbar spine and proximal femur. More recently, TBS has been shown to have predictive value for fracture independent of fracture probabilities using the FRAX(R) algorithm. Although TBS changes with osteoporosis treatment, the magnitude is less than that of aBMD of the spine, and it is not clear how change in TBS relates to fracture risk reduction. TBS may also have a role in the assessment of fracture risk in some causes of secondary osteoporosis (e.g. diabetes, hyperparathyroidism and glucocorticoid-induced osteoporosis). In conclusion, there is a role for TBS in fracture risk assessment in combination with both aBMD and FRAX. [less ▲]Detailed reference viewed: 4 (1 ULg) Sur Capitalisme, désir et servitude. Lettre à Frédéric LordonPieron, Julien in Dissensus (in press), 6(printemps 2014), Detailed reference viewed: 29 (3 ULg) All for a container: Technological mediation, transnational business and love affairsJedlowski, Alessandro in Transfers: Interdisciplinary Journal of Mobility Studies (in press)This paper analyzes the articulation between mobility and technology within life trajectories marked by migration, exile and the search for economic achievement. It does so by focusing on a Nigerian ... [more ▼]This paper analyzes the articulation between mobility and technology within life trajectories marked by migration, exile and the search for economic achievement. It does so by focusing on a Nigerian couple’s (attempted) itinerary of return migration from Italy to Nigeria, and on the role played by a specific transport technology, the shipping container, within this process. It highlights how, throughout the itinerary that brings the container from Italy to Nigeria, its social meaning and value become the center of a series of tense interactions, in which different conceptions of family hierarchies, contrasting spiritual beliefs, as well as diverging imaginaries about transnational mobility, migration and life abroad come to the fore, and provoke radical transformations in the life of the people involved in the itinerary of the container itself [less ▲]Detailed reference viewed: 29 (8 ULg) One-year prevalence of migraine using a validated extended French version of the ID MigraineTM: a Belgian population-based studyStreel, Sylvie ; Donneau, Anne-Françoise ; Hoge, Axelle et alin Revue Neurologique (in press)Detailed reference viewed: 16 (4 ULg) Les voyages du goût, entre localité et exotisme.Mescoli, Elsa in Anthropology of Food (in press)« Savourer la nourriture et respirer la culture marocaine deviennent une expérience et une émotion unique, à découvrir et à vivre grâce à la combinaison d’arômes, goûts, couleurs, formes et musiques ». Au ... [more ▼]« Savourer la nourriture et respirer la culture marocaine deviennent une expérience et une émotion unique, à découvrir et à vivre grâce à la combinaison d’arômes, goûts, couleurs, formes et musiques ». Au travers de ce slogan, un renommé restaurant d’inspiration marocaine de la ville de Milan en Italie, invitait ses clients à voyager au travers de leur sensorialité dans une culture alimentaire (et par synecdoque, une culture tout court) autre. Le goût les aurait amenés à expérimenter un exotisme, qui était néanmoins contrôlé, car certaines conditions imposées par les normes locales faisaient en sorte que le déplacement vécu ne fût pas excessivement déstabilisant. Le résultat de ces négociations consistait d’un menu qui accostait les gastronomies marocaine et italienne (ou les procédures de l’une et de l’autre) dans certains plats décrits comme « fusion », qui satisfaisaient (ou non) les exigences des clients. Dans cet article, je vise à mettre en évidence les mécanismes de production discursive et matérielle de ces plats, ainsi comme les opinions des consommateurs. Pour ce faire, j’analyserai le matériel ethnographique collecté auprès du local en question en le comparant avec les pratiques observés dans d’autres restaurants milanais. En ce qui concerne les effets obtenus, j’appuierait mon analyse sur une plateforme de médias sociaux consacrée aux recensions d’endroits et locaux touristiques. La culture alimentaire sera étudiée dans ses aspects symboliques mais aussi matériels, en faisant également recours au matériel visuel récolté. [less ▲]Detailed reference viewed: 35 (9 ULg) Réduire l’altérité au travers des processus de traduction et de représentationLeclercq, Bruno ; Smette, Bernard in Doctorales. Revue LLA-SHS de Montpellier (in press)WVO Quine questions the « myth » of an ideal realm of shared meanings which every national language would express in its own way. Against the hope of transparent translations, he insists on the necessity ... [more ▼]WVO Quine questions the « myth » of an ideal realm of shared meanings which every national language would express in its own way. Against the hope of transparent translations, he insists on the necessity for building equivalences from one language to another through a strategy of reducing the differences in rationality among nations as much as possible. According to Quine, otherness is not insuperable impediment to meeting/encounter and mutual understanding ; by throwing our conceptual schemes on the other communities’ uses/practices – which of course involves some symbolic violence – gaps can always been narrowed. Similarly E. Laclau questions the traditional conception of political representation, which is seen as the transparent process of transmitting someone’s will or interests on another level. For this ideal conception of representation, Laclau substitutes a pragmatic conception which takes in account the irreducible gap between the actors as well as the constitutive opacity of the process of representation : the subject’s will is constituted within the process of representation and through the representative’s productive role. In order to be transposed at the decision-making level, the subject’s interests must be translated by the representative as well as be negotiated with the other represented interests. This implies that the initial will undergoes some identity transformations. [less ▲]Detailed reference viewed: 19 (9 ULg) One injection of platelet-rich plasma associated to a submaximal eccentric protocol to treat chronic jumper's kneeKaux, Jean-François ; Croisier, Jean-Louis ; Bruyère, Olivier et alin The Journal of sports medicine and physical fitness (in press)INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. METHODS: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months after the infiltration, using a 10--point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA--P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub--maximal eccentric reeducation. RESULTS: Pain during daily activities significantly decreased with time. During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. CONCLUSION: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol can improve symptoms of chronic jumper's knee in patients non--responsive to classical conservative treatments. [less ▲]Detailed reference viewed: 85 (29 ULg) The Sceptical President: Václav Klaus' Influence on Czech Public Opinion on Climate ChangeDe Pryck, Kari; Gemenne, François in Climatic Change (in press)Detailed reference viewed: 88 (1 ULg) Testing the proportional odds assumption in multiply imputed ordinal longitudinal dataDonneau, Anne-Françoise ; Mauer, M; Lambert, Philippe et alin Journal of Applied Statistics (in press)Detailed reference viewed: 12 (2 ULg) Levallois et GravettienOtte, Marcel ; Noiret, Pierre in Praehistoria (in press)Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein ... [more ▼]Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein du Gravettien touchent autant les processus de symbolisation dans l’art et les sépultures. Elles affectent différents substrats eurasiatiques, plutôt septentrionaux, comme mis en réserve dès les Néandertaliens. [less ▲]Detailed reference viewed: 48 (6 ULg) Identification of cardiac repercussions after intense and prolonged concentric isokinetic exercise in young sedentary people.LE GOFF, Caroline ; Kaux, Jean-François ; Couffignal, Vincent et alin Clinical physiology and functional imaging (in press)INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among ... [more ▼]INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among those who are unaware of their heart condition. The development of cardiospecific biochemical markers has led to a reconsideration of the role of biology in the diagnosis of cardiovascular illnesses. The aim of this study therefore was, through the use of cardiac biomarker assays, to highlight the impact of sustained physical effort in the form of intense and prolonged concentric isokinetic exercise and to research potential cardiovascular risks. MATERIALS AND METHODS: Eighteen subjects participated in a maximal concentric isokinetic exercise involving 30 knee flexion-extensions for each leg. Five blood tests were taken to study the kinetics of the cardiac biomarkers. Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: The results showed significant increases in the creatine kinase, myoglobin, homocysteine and haemoglobin cardiac markers. Evolutionary trends were also observed for the following biomarkers: NT-proBNP, myeloperoxydase and C-reactive protein. All the physiological parameters measured presented statistically significant changes. CONCLUSION: Isokinetic effort leads to the release of cardiac markers in the blood, but these do not exceed the reference values in healthy subjects. Maximal concentric isokinetic exercise does not, therefore, lead to an increased risk of cardiovascular pathologies. [less ▲]Detailed reference viewed: 80 (33 ULg) Enzymatic hydrolysis of softwood and hardwood regenerated cellulosesJacquet, Nicolas ; Maniet, Guillaume ; Richel, Aurore et alin Current Chemical Biology (in press)Regenerated celluloses from Kraft wood pulps (from hardwoods and softwoods) were hydrolysed by mean of cellulase of Trichoderma reesei. Our results highlighted that a 75% hydrolysis yield was reached for ... [more ▼]Regenerated celluloses from Kraft wood pulps (from hardwoods and softwoods) were hydrolysed by mean of cellulase of Trichoderma reesei. Our results highlighted that a 75% hydrolysis yield was reached for hardwood regenerated cellulose (HRC) and 90% for softwood regenerated cellulose (SRC). Crystallinity indices from X-Ray diffraction patterns were used to measure hydrolysis rate of crystalline and amorphous regions. Addition of β-glucosidase to the enzymatic complex of Trichoderma reesei was confirmed to enhance yields of hydrolysis. [less ▲]Detailed reference viewed: 38 (10 ULg) Caractérisation des systèmes sol-plante dans les collines de l’arc cuprifère du Katanga - revue bibliographiqueKaya Muyumba, Donato; Liénard, Amandine ; Mahy, Grégory et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)Introduction: The Copper belt of Katanga presents huge resources of Cu and Co-ore. On the copper hills, mineralized rocks outcrop and a specific flora did develop as a response to the high levels of Cu ... [more ▼]Introduction: The Copper belt of Katanga presents huge resources of Cu and Co-ore. On the copper hills, mineralized rocks outcrop and a specific flora did develop as a response to the high levels of Cu and Co in soil. Soil-vegetation relationships need to be understood in order to elaborate biodiversity conservation programs prior to industrial mining of the copper hills. Literature: This paper reviews knowledge about soil characterization in the copper hills of Katanga and makes proposals for further research about the influence of the very specific chemical conditions of contaminated soils on the vegetation. The focus was put on the geochemical background and the bioavailability of Cu and Co. A lot of progress has been made recently about identification of soil-vegetation relationships. Conclusion: However, the issue of Cu and Co mobility within soil-plant systems is not entirely solved. [less ▲]Detailed reference viewed: 29 (9 ULg) Thin film superconducting shieldsClaassen, John; Osofsky, Michael; Namburi, Devendra et alin IEEE Transactions on Applied Superconductivity (in press)To date, magnetic shields utilizing high-temperature superconductor materials mostly comprise bulk materials, usually shaped into a cylinder and then heat treated. We analyze the potential of thin-film ... [more ▼]To date, magnetic shields utilizing high-temperature superconductor materials mostly comprise bulk materials, usually shaped into a cylinder and then heat treated. We analyze the potential of thin-film technology, whereby a layer of superconductor is deposited on a substrate, to fabricate magnetic shields. Films deposited on a curved surface are inevitably granular, leading to reduced critical current density compared with crystalline films. This limits the maximum field that can be screened. Granular films also have an enhanced penetration depth compared with the bulk value, which determines the maximum possible screening at applied fields below the maximum.We demonstrate the utility of a mutual inductancemeasurement to evaluate small flat test samples of a granular film for their potential as a shielding material in a more complex geometry. Thismeasurement predicts both themaximum magnetic field that can be screened and the residual leakage at fields below the maximum. The tested film was produced by the Electrophoretic deposition of YBCO on a silver substrate. The maximum screening field was comparable with that obtained for a similar film on a cylindrical substrate. We also show comparable results from a crystalline YBCO film. [less ▲]Detailed reference viewed: 26 (2 ULg) Négocier une majorité politique et devenir bourgmestre en Belgique. Quelles influences des droits régionaux ?Grandjean, Geoffrey in Revue Régionale de Droit (in press)Depuis 2001, les Régions sont compétentes en matière d’organisation et d’élection des pouvoirs locaux. Elles ont adopté des règles différentes. Dans quelle mesure ces règles influencent-elles la ... [more ▼]Depuis 2001, les Régions sont compétentes en matière d’organisation et d’élection des pouvoirs locaux. Elles ont adopté des règles différentes. Dans quelle mesure ces règles influencent-elles la négociation d’une majorité politique et la désignation des bourgmestres en Belgique ? Afin de répondre à cette question, des entretiens semi-directifs ont été réalisés avec plusieurs bourgmestres et échevin issus de communes localisées dans les trois Régions. Des différences entre Régions mais également au sein de celles-ci ont été relevées. Les dispositions relatives au mode de désignation du bourgmestre sont primordiales pour comprendre les dynamiques de négociations politiques. Au final, cet article tisse les liens entre les normes juridiques et les jeux des acteurs politiques. [less ▲]Detailed reference viewed: 32 (3 ULg) Validation of the analytical procedure for the determination of malondialdehyde and three other aldehydes in vegetable oil using Liquid Chromatography coupled to tandem mass spectrometry (LC-MS/MS) and application to linseed oilDouny, Caroline ; Tihon, Angélique; Bayonnet, Pierre et alin Food Analytical Methods (in press)Detailed reference viewed: 37 (9 ULg) Magie et pharmacopée : l’utilisation des végétaux dans les papyrus iatromagiques grecsde Haro Sanchez, Magali in Mythos (in press)The iatromagical papyri, subgenus of the magical papyri, come from Egypt. From the 1st BC to AD the 7th, they appear in the form of formularies, spells copied from them, amulets and a private letter. For ... [more ▼]The iatromagical papyri, subgenus of the magical papyri, come from Egypt. From the 1st BC to AD the 7th, they appear in the form of formularies, spells copied from them, amulets and a private letter. For many years, the study of these texts has been part of a research program of the Centre de Documentation de Papyrologie Littéraire (CeDoPaL) of the University of Liège. We will present here the results from the analysis of the content of the prescriptions with plants attested in the Greek iatromagical formularies. [less ▲]Detailed reference viewed: 237 (28 ULg) Survivances et métamorphoses. Les gemmes isiaques remployées au Moyen Âge et leur interprétationVeymiers, Richard in Anabases : Traditions et Réception de l'Antiquité (in press)Detailed reference viewed: 15 (0 ULg) La première interprétation heideggérienne de la MonadologiePieron, Julien in Philosophie (in press)Detailed reference viewed: 52 (8 ULg) Defensins: « simple » antimicrobial peptides or broad-spectrum molecules ?Suarez-Carmona, Meggy ; Hubert, Pascale ; Delvenne, Philippe et alin Cytokine & Growth Factor Reviews (in press)Detailed reference viewed: 17 (4 ULg) Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countriesCastano, Argelia; Cutanda, Francisco; Esteban, Marta et alin Environmental Research (in press)The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential ... [more ▼]The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential neurodevelopmental effects of early life exposure to low-​levels of MeHg. Therefore, it is important that pregnant women, children and women of childbearing age are, as far as possible, protected from MeHg exposure. Within the European project DEMOCOPHES, we have analyzed mercury (Hg) in hair in 1799 mother-​child pairs from 17 European countries using a strictly harmonized protocol for mercury anal. Parallel, harmonized questionnaires on dietary habits provided information on consumption patterns of fish and marine products. After hierarchical cluster anal. of consumption habits of the mother-​child pairs, the DEMOCOPHES cohort can be classified into two branches of approx. similar size: one with high fish consumption (H) and another with low consumption (L)​. All countries have representatives in both branches, but Belgium, Denmark, Spain, Portugal and Sweden have twice as many or more mother-​child pairs in H than in L. For Switzerland, Czech Republic, Hungary, Poland, Romania, Slovenia and Slovakia the situation is the opposite, with more representatives in L than H. There is a strong correlation (r=0.72) in hair mercury concn. between the mother and child in the same family, which indicates that they have a similar exposure situation. The clustering of mother-​child pairs on basis of their fish consumption revealed some interesting patterns. One is that for the same sea fish consumption, other food items of marine origin, like seafood products or shellfish contribute significantly to the mercury levels in hair. We conclude that addnl. studies are needed to assess and quantify exposure to mercury from seafood products, in particular. The cluster anal. also showed that 95​% of mothers who consume once per wk fish only, and no other marine products, have mercury levels 0.55 μg​/g. Thus, the 95th percentile of the distribution in this group is only around half the US-​EPA recommended threshold of 1 μg​/g mercury in hair. Consumption of freshwater fish played a minor role in contributing to mercury exposure in the studied cohort. The DEMOCOPHES data shows that there are significant differences in MeHg exposure across the EU and that exposure is highly correlated with consumption of fish and marine products. Fish and marine products are key components of a healthy human diet and are important both traditionally and culturally in many parts of Europe. Therefore, the communication of the potential risks of mercury exposure needs to be carefully balanced to take into account traditional and cultural values as well as the potential health benefits from fish consumption. European harmonized human biomonitoring programs provide an addnl. dimension to national HMB programs and can assist national authorities to tailor mitigation and adaptation strategies (dietary advice, risk communication, etc.) to their country's specific requirements. [less ▲]Detailed reference viewed: 97 (19 ULg) Clinical pharmacology of antifungal agents to overcome drug resistance in pediatric patientsSTERGIOPOULOU, Theodouli ; Walsh, Thomas J.in Expert opinion on pharmacotherapy (in press), 16(2), 213-26INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological ... [more ▼]INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological management is critical for the successful treatment of invasive fungal infections by resistant strains. AREAS COVERED: This paper reviews the mechanisms of resistance of different classes of antifungal agents and the current understanding of pediatric antifungal pharmacology for overcoming antifungal resistance in children based on laboratory and clinical studies in the English literature. The therapeutic choices against fungal pathogens with intrinsic or acquired resistance are further reviewed. EXPERT OPINION: There is a paucity of data in the pediatric population regarding the epidemiology of the resistant organisms to different antifungal agents. It is also unknown if there are more prevalent molecular mechanisms that promote antifungal resistance. Selection and dosages of the most effective antifungal agent for overcoming the antifungal resistance is crucial. However, there are limited studies guiding the optimal dosage and duration of treatment for management of emergent antifungal resistance. Further studies are warranted to elucidate the optimal pharmacology of the current antifungal agents against resistant organisms and to advance the development of new antifungal agents. [less ▲]Detailed reference viewed: 15 (1 ULg) De l’usage de la photographie dans une enquête ethno-sociologique sur la mémoire de l’exil et de l’immigration espagnols en BelgiqueMolina Marmol, Maïté in RELAIS Revue du laboratoire d'études et de recherches sur l'interculturel (in press)Detailed reference viewed: 38 (5 ULg) Exploratory Single Grain OSL data analysis of quartz from archeological mortars: on the use of an exponential distribution of light exposure of grains and consequences for datingGuibert, Pierre; Urbanova, Petra; Blain, Sophie et alin Radiation Measurements (in press)Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching ... [more ▼]Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching state of the series of quartz grains extracted from a mortar sample. Indeed, during the making process, sand is extracted from a sedimentary source, transported, stored then mixed with lime and set into the walls being constructed. Experience shows that incomplete bleaching is frequent for these materials. The aim of this study is to model the distribution of single grain equivalent doses of mortars following the assumption that a population of grains corresponds to a unique distribution of heterogeneously bleached grains rather than to a mixture of well bleached quartz grains with poorly bleached ones. An exponential distribution of light exposure of grains is examined. By comparing experimental distributions of doses with simulated ones, we investigate the appropriateness of this distribution function and then we calculate the average residual dose integrated into the process of the ED determination and finally the OSL age. Limits and potentials of this approach are discussed using various case-studies of structures and buildings of known age (from the roman to the post-medieval period). Even in case of very poorly bleached samples we observed that the simulated ED distribution fits satisfactorily with the experimental one, which offers new encouraging perspectives in single grain dating of mortars. [less ▲]Detailed reference viewed: 29 (3 ULg) Neoformed mineral phases during clay ceramic firingEl Ouahabi, Meriam ; Daoudi, Lachen; Hatert, Frédéric et alin Clays and Clay Minerals (in press)Ceramic clays are one of the most complicated ceramic systems because of the very complex relationship between the behavior of minerals during the ceramic processing and the transformations during heating ... [more ▼]Ceramic clays are one of the most complicated ceramic systems because of the very complex relationship between the behavior of minerals during the ceramic processing and the transformations during heating. A major challenge is to predict the phase transformations in clay ceramics. The aims are to establish reference data of ceramics products that can be formed based on the mineralogical composition of the local raw materials. These data, in turn, can be compared with the archaeological ceramics in order to study their origins. The mineralogical compositions and transformations during the firing (550 to 1100ºC under oxidizing conditions) of seven clayey materials sampled from the main clay deposits of Northern Morocco were evaluated by X-ray powder diffraction. Two groups of clays were evidenced according to the type of neoformed high-temperature minerals: non-calcareous clays and calcareous clays. For the non-calcareous raw materials, spinel is produced at 950°C. Cristobalite and mullite were formed above 1000ºC from clays that contain illite, kaolinite and chlorite. In clays containing vermiculite and high amount of chlorite, hematite was formed from 950°C. Firing of calcareous clays at temperatures > 950ºC yielded Ca-silicates (diopside, gehlenite and wollastonite), spinel, cristobalite, hematite and feldspars. Mullite may also form in the calcareous clay products, when the carbonates content exceeds 10%. [less ▲]Detailed reference viewed: 74 (26 ULg) Experimental and numerical study of the flight of geeseDimitriadis, Grigorios ; Gardiner, James; Tickle, Peter et alin Aeronautical Journal (in press)The flight of barnacle geese at airspeeds representing high-speed migrating flight is investigated using experiments and simulations. The experimental part of the work involved the filming of three ... [more ▼]The flight of barnacle geese at airspeeds representing high-speed migrating flight is investigated using experiments and simulations. The experimental part of the work involved the filming of three barnacle geese (Branta Leucopsis) flying at different airspeeds in a wind tunnel. The video footage was analysed in order to extract the wing kinematics. Additional information, such as wing geometry and camber was obtained from a 3D scan of a dried wing. An unsteady vortex lattice method was used to simulate the aerodynamics of the measured flapping motion. The simulations were used in order to successfully reproduce the measured body motion and thus obtain estimates of the aerodynamic forces acting on the wings. It was found that the mean of the wing pitch angle variation with time has the most significant effect on lift while the difference in the durations of the upstroke and downstroke has the major effect on thrust. The power consumed by the aerodynamic forces was also estimated; it was found that increases in aerodynamic power correspond very closely to climbing motion and vice versa. Root-mean-square values of the power range from 100 W to 240 W. Finally, it was observed that tandem flying can be very expensive for the trailing bird. [less ▲]Detailed reference viewed: 47 (4 ULg) Per una edizione integrale e analitica dell'incipit della Storia d'Italia di Francesco GuicciardiniMoreno, Paola in Laboratoire Italien : Politique et Société (in press)Detailed reference viewed: 44 (17 ULg) La « nouvelle orthographe » n'est-elle qu'une question d'orthographe ? Le cas du pluriel des noms empruntésBaiwir, Esther ; Steffens, Marie in Français Moderne (Le) (in press)Detailed reference viewed: 50 (12 ULg) Le phénotype d’Akhenaton ; revue critique entre canons artistiques et expression pathologique.JEDIDI, Zayd ; JEDIDI, Haroun ; LAVEAUX, Elisabeth et alin Revue Médicale de Liège (in press)Of all the royal families of ancient or modern fame, few are as iconic as the eighteenth dynasty of pharaohs of the New Kingdom of Egypt, whose opulence and deeds we are still familiar to nearly 3,500 ... [more ▼]Of all the royal families of ancient or modern fame, few are as iconic as the eighteenth dynasty of pharaohs of the New Kingdom of Egypt, whose opulence and deeds we are still familiar to nearly 3,500 years after their time. Tenth pharaoh of this dynasty and father of Tutankhamun, Akhenaten (Amenhotep/Amenhotep IV) still fascinates Egyptologists and history lovers through the many questions surrounding his atypical rule. One of the most striking aspects of the so-called Amarna period concerns the representations of the pharaoh himself, very confusing compared to the traditional iconography of the New Kingdom. These intriguing portraits of Pharaoh raised a whole lot of medical assumptions, more or less substantiated. We review here the main theories developed throughout history. [less ▲]Detailed reference viewed: 34 (8 ULg) Practical management of Chronic Myeloid Leukemia in BelgiumBenghiat, FS.; Beguin, Yves ; Dessars, B. et alin Belgian Journal of Hematology (in press)Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation ... [more ▼]Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation tyrosine kinase inhibitors (TKIs) and the possibility of treatment discontinuation made the management of these patients more challenging. In this review, practical management guidelines of CML are presented, adapted to the Belgian situation in 2014. In first line chronic phase patients, imatinib, nilotinib and dasatinib can be prescribed. While second generation TKIs give faster and deeper responses, their impact on long-term survival remain to be determined. The choice of the TKI depends on CML risk score, priority for a deep response to allow a treatment-free remission protocol, age, presence of comorbid conditions, side effect profile, drug interactions, compliance concerns and price. Monitoring the response has to be made according the 2013 ELN criteria, and is based on the bone-marrow cytogenetic response during the first months and on the blood molecular response. Molecular follow-up is sufficient in patients with a complete cytogenetic response. For patients who fail frontline therapy, nilotinib, dasatinib, bosutinib and ponatinib are an option depending of the type of intolerance or resistance. T315I patients are only sensitive to ponatinib, which has to be carefully handled due to cardiovascular toxicity. Advanced phase diseases are more difficult to handle, with treatments including allogeneic stem cell transplantation, which is also an option for patients failing at least two TKIs. The possibility of treatment-free remission and pregnancy are also discussed. [less ▲]Detailed reference viewed: 71 (3 ULg) Le point sur l’évaluation de la force des muscles respiratoiresKellens, Isabelle ; Crielaard, Jean-Michel in Revue Médicale de Liège (in press)The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect ... [more ▼]The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect, voluntary or involuntary. The conventional spirometry method assesses indirectly the respiratory function by measuring maximum inspiratory and expiratory pressure, which reflects the coordination of all respiratory muscles. Techniques of magnetic and electrical stimulation can detect a specific muscle dysfunction, independently of the patient's motivation, however they are invasive methods as measurements are made in the esophagus and stomach. The voluntary techniques are generally non-invasive and require patient's cooperation. Measures of respiratory muscle strength, coupled to a conventional spirometry, can predict the development of ventilatory support in patients at risk, and may be useful during weaning from mechanical ventilation in intensive care units. [less ▲]Detailed reference viewed: 162 (42 ULg) Monitoring Antibiotic Use and Residue in Freshwater Aquaculture for Domestic Use in VietnamPham Kim, Dang; Chu, Jacqueline; Nga Thuy, Do et alin EcoHealth (in press)Detailed reference viewed: 28 (4 ULg) “How are you Vulnerable?”: Using Participation for Vulnerability Analysis in Emergency PlanningRossignol, Nicolas ; Turcanu, Catrinel; Fallon, Catherine et alin Journal of Risk Research (in press)Scientists in many fields of research have developed models, theories and concepts attempting to grasp and manage dangers that are often difficult to imagine. Among the different perspectives, the Science ... [more ▼]Scientists in many fields of research have developed models, theories and concepts attempting to grasp and manage dangers that are often difficult to imagine. Among the different perspectives, the Science and Technology Studies (STS) Vulnerability Approach seems very promising. Relying on a constructivist paradigm, it is based on an inductive collection and analysis of a wide range of factors, with a particular focus on cultural factors and actual day-to-day practices. In this paper, we present the roots of this approach and we display findings based on three case studies exploring emergency planning in three different contexts (a city near a SEVESO plant, a school near a nuclear plant, and a city confronted to multiple catastrophic scenarios). The cases studies were realized by conducting three Focus Groups with different types of stakeholders (citizens, teachers, firemen, decision makers, etc.). After presenting the results of the case studies, we discuss how stakeholders’ participation can inform such type of vulnerability analysis in the context of emergency planning. We argue that participation fosters a deep understanding of actual safety governance practices which allows innovative results to emerge as well as it initiates a learning process among the participants. It contributes to questioning the relations between decision-makers, experts and citizens. It has the potential of bypassing the positivist and quantitative rationale of safety, and thus, of redefining the vulnerability governance. As a conclusion, we question the role of such STS vulnerability approach within the actual vulnerability governance. [less ▲]Detailed reference viewed: 51 (12 ULg) Les recettes de l’Autre. De la transmission des savoirs (et savoir-faire) féminins en contexte migratoire.Mescoli, Elsa in Hommes & Migrations (in press)La plupart des études sur la connexion entre alimentation et migration sont assez récentes. Elles mettent tout d’abord en évidence le fait que, lors d’un déplacement, les individus ou les groupes sont ... [more ▼]La plupart des études sur la connexion entre alimentation et migration sont assez récentes. Elles mettent tout d’abord en évidence le fait que, lors d’un déplacement, les individus ou les groupes sont confrontés à des styles alimentaires différents. Ces recherches s’engagent alors à vérifier dans quelle mesure cette rencontre défie l’identité individuelle (Cardona, 2004; Crenn, 2004; Spiro, 1955) et quelles pratiques elle engage afin de la préserver (Hage, 1997; Beyers, 2008; Diner and Diner, 2009). L’attention est ainsi portée au contexte domestique dans lequel les familles issues de la migration préparent leurs repas et, potentiellement, définissent leur appartenance culturelle. Une deuxième direction entreprise par ces études, concerne par contre l’espace public : par exemple, les ainsi dits « restaurants ethniques » font l’objet de nombreuses recherches qui visent cette fois à analyser la consommation de l’ « exotique » de la part des membres de la population majoritaire (Hassoun & Raulin, 1995; Régnier, 2005). Ces deux dimensions principales sont rarement abordées dans leur superposition, fait qui laisse dans l’ombre des dynamiques pareillement pertinentes. Notamment, nous pourrions relever les enjeux liés à la préparation de nourriture conçue comme pratique du quotidien destinée à être exportée en contexte non-domestique et offerte à des individus qui, non seulement ne font pas partie de la famille de ceux qui cuisinent, mais sont aussi associés à une appartenance culturelle différente. L’étude de ces enjeux amène à constater que la définition active de soi au travers de la pratique culinaire s’entremêle à la volonté d’en transmettre une image aux autres. En particulier, lorsqu’on adopte une perspective de genre et que l’on focalise l’attention sur les femmes migrantes, nous sommes amenés à noter comment un de ces savoir-faire qui constituent des potentiels dispositifs de domestication (Rogers, 1981) se transforme en instrument de visibilité, et ainsi de participation, dans l’espace public. Dans cet article, afin de mettre en évidence la complexité de ces dynamiques, je présenterai en clef comparative des exemples collectés dans le cadre de mes recherches autour du lien entre alimentation et migration. J’analyserai les pratiques culinaires exercées en contexte public d’un côté par un groupe de femmes marocaines résidentes en Italie, de l’autre par certaines femmes italiennes résidentes en Belgique. La comparaison des choix des femmes, faits en fonction des destinataires mais aussi en réponse aux différents contextes sociopolitiques dans lesquels certaines manifestations culinaires prennent la forme de « rencontres interculturelles », permettra de donner un aperçu sur la façon dont les femmes considérées s’assurent une place active dans l’espace vécu. Le texte sera illustré par des images collectées durant l’ethnographie. [less ▲]Detailed reference viewed: 15 (1 ULg) Périls de la copie : les cas de l’Estoire del Saint Graal, du Merlin et de la Suite VulgateCombes, Annie in Cahiers de Civilisation Médiévale (in press)Detailed reference viewed: 37 (11 ULg) Reduced Order Analysis of Aeroelastic Systems with Freeplay using an Augmented Modal BasisSilva, Gustavo H. C.; Dal Ben Rossetto, Gustavo; Dimitriadis, Grigorios in Journal of Aircraft (in press)Freeplay in aircraft control surface actuators is a common source of nonlinearity that can cause undesirable aeroelastic phenomena and, as a consequence, certification authorities place strict limits on ... [more ▼]Freeplay in aircraft control surface actuators is a common source of nonlinearity that can cause undesirable aeroelastic phenomena and, as a consequence, certification authorities place strict limits on the size of the deadband gaps of actuators. In recent years many authors have worked on determining the effects of freeplay on the dynamic behavior of aeroelastic systems; these efforts have yielded significant improvements in the understanding of the phenomena, but have concentrated on simple models. Investigations of industry-relevant aeroelastic models of complete aircraft with freeplay in the actuators have been much rarer, the main difficulty being the selection of an appropriate modal basis that can represent the full range of possible dynamic phenomena. This work presents a novel implementation of the residual vectors approach to create consistent and numerically stable reduced order models suitable for industrial-standard aeroelastic models of aircraft. The methodology relies on the piecewise linear nature of freeplay to create a single reduction basis that represents the dynamics of the system both inside and outside the freeplay deadband gap. The method is demonstrated on an Embraer generic test bench aircraft, showing that the resulting reduced order model is efficient and effective. Nonlinear analysis is carried out using equivalent linearization as well as time integrations of the full nonlinear system. It is shown that, while equivalent linearization is an indispensable tool for a preliminary mapping of the main aeroelastic instabilities, the time integration-based nonlinear analysis is an essential complementary tool to confirm the characteristics of the system behavior. [less ▲]Detailed reference viewed: 56 (5 ULg) Neural correlates of personal goal processing during episodic future thinking and mind-wandering: an ALE meta-analysisStawarczyk, David ; D'Argembeau, Arnaud in Human Brain Mapping (in press)The ability to imagine the future is a complex mental faculty that depends on an ensemble of cognitive processes supported by an extended set of brain regions. Our aim here was to shed light on one key ... [more ▼]The ability to imagine the future is a complex mental faculty that depends on an ensemble of cognitive processes supported by an extended set of brain regions. Our aim here was to shed light on one key component of future thinking—personal goal processing—and to determine its neural correlates during both directed and spontaneous forms of thoughts. To address this question, we performed separate ALE meta-analyses of neuroimaging studies of episodic future thinking, mind-wandering, and personal goal processing, and then investigated the commonalities and differences in brain activity between these three domains. The results showed that the three domains activated a common set of brain regions within the default network and, most notably, the medial prefrontal cortex. This finding suggests that the medial prefrontal cortex mediates the processing of personal goals during both episodic future thinking and mind-wandering. Differences in activation were also observed, and notably regions supporting cognitive control processes (the dorsolateral prefrontal cortex) were recruited to a lesser extent during mind-wandering than experimentally directed future thinking, suggesting that different kinds of self-generated thoughts may recruit varying levels of attentional control abilities. [less ▲]Detailed reference viewed: 57 (2 ULg) Modulating effect of COMT Val158Met polymorphism on interference resolution during a working memory taskJaspar, Mathieu ; DIDEBERG, Vinciane ; Bours, Vincent et alin Brain & Cognition (in press)Genetic variability related to the catechol-O-methyltransferase (COMT) gene has received increasing attention in the last 15 years, in particular as a potential modulator of the neural substrates ... [more ▼]Genetic variability related to the catechol-O-methyltransferase (COMT) gene has received increasing attention in the last 15 years, in particular as a potential modulator of the neural substrates underlying inhibitory processes and updating in working memory (WM). In an event-related functional magnetic resonance imaging (fMRI) study, we administered a modified version of the Sternberg probe recency task (Sternberg, 1966) to 43 young healthy volunteers, varying the level of interference across successive items. The task was divided into two parts (high vs. low interference) to induce either proactive or reactive control processes. The participants were separated into three groups according to their COMT Val158Met genotype [Val/Val (VV); Val/Met (VM); Met/Met (MM)]. The general aim of the study was to determine whether COMT polymorphism has a modulating effect on the neural substrates of interference resolution during WM processing. Results indicate that interfering trials were associated with greater involvement of frontal cortices (bilateral medial frontal gyrus, left precentral and superior frontal gyri, right inferior frontal gyrus) in VV homozygous subjects (by comparison to Met allele carriers) only in the proactive condition of the task. In addition, analysis of peristimulus haemodynamic responses (PSTH) revealed that the genotype-related difference observed in the left SFG was specifically driven by a larger increase in activity from the storage to the recognition phase of the interfering trials in VV homozygous subjects. These results confirm the impact of COMT genotype on inhibitory processes during a WM task, with an advantage for Met allele carriers. Interestingly, this impact on frontal areas is present only when the level of interference is high, and especially during the transition from storage to recognition in the left superior frontal gyrus. [less ▲]Detailed reference viewed: 55 (3 ULg) Les détournements de jeux vidéo par les joueurs : une incarnation du playBarnabé, Fanny in RESET - Recherches en Sciences Sociales sur Internet (in press), (4), Cet article a pour objectif d’analyser conjointement quatre pratiques de détournement du jeu vidéo par les joueurs (la rédaction de fanfictions, la réalisation de machinimas, le modding, et le speedrun ... [more ▼]Cet article a pour objectif d’analyser conjointement quatre pratiques de détournement du jeu vidéo par les joueurs (la rédaction de fanfictions, la réalisation de machinimas, le modding, et le speedrun) en les envisageant comme des prolongements de l’expérience ludique. La forme des œuvres dérivées ainsi que les discours des joueurs qui les produisent seront étudiés parallèlement dans le but de mettre au jour en quoi ces pratiques renouvellent la conception même du jeu et lui ouvrent de nouveaux espaces. Ce travail se veut donc dans la lignée des play studies définies par Triclot (2011), qui envisagent le jeu vidéo non comme une forme figée mais comme une expérience. Précisément, trois points de passage assurant une continuité entre le jeu et ses réappropriations seront ici envisagés. Tout d’abord, la pratique du jeu vidéo et celle du détournement seront rapprochées en tant qu’elles se définissent toutes deux comme des performances (à la fois d’un point de vue technique et d’un point de vue interprétatif). Ensuite, nous envisagerons (notamment à l’aide du concept d’« affordance ») les différents moyens par lesquels les réappropriations peuvent – mimant le jeu – inciter leur récepteur à adopter une attitude ludique. Enfin, les recoupements entre la posture du joueur et celle du créateur de détournements suggèrent l’inclusion de ces pratiques de création dans un « play » généralisé. [less ▲]Detailed reference viewed: 20 (4 ULg) Conditions de travail, stress et burnout des professionnels belges de radiothérapie: analyse comparative et exploration du rôle du travail émotionnelLaurent, Julie ; BRAGARD, Isabelle ; COUCKE, Philippe et alin Cancer Radiotherapie (in press)Detailed reference viewed: 80 (37 ULg) BHS guidelines for the treatment of Burkitt lymphomaBONNET, Christophe ; Janssens, A.; Wu, KL. et alin Belgian Journal of Hematology (in press)Burkitt lymphoma (BL) is a rare but very aggressive non-Hodgkin’s lymphoma characterized by an isolated translocation t(8;14)(q24;q32). The sporadic form is the subentity most frequently encountered in ... [more ▼]Burkitt lymphoma (BL) is a rare but very aggressive non-Hodgkin’s lymphoma characterized by an isolated translocation t(8;14)(q24;q32). The sporadic form is the subentity most frequently encountered in our country. Diagnosis and initial work-up must be completed rapidly to start treatment as soon as possible. Positron emission tomography (PET) scan is useful for initial staging and to evaluate the chemosensitivity of the tumor during and after treatment. After debulking, it is recommended to add rituximab to chemotherapy. Currently intensive short-cycle chemotherapies (ISCC) and low intensity chemotherapies (LIC) are two valuable options. Radiotherapy is not indicated except in case of central nervous system involvement. Patients achieving complete remission must be followed carefully during the first year to detect recurrence of the disease. More than 80% of patients sustain their remission one year following initial treatment and are considered cured. For patients in partial remission or with chemosensitive relapse, autologous stem cell transplantation is recommended following re-induction with non-cross-resistant polychemotherapy. Monitoring complete blood counts and cognitive functions is important to detect late toxicity of the applied therapies. [less ▲]Detailed reference viewed: 49 (4 ULg) Short communication: Evaluation of the microbiota of kefir samples using metagenetic analysis targeting the 16S and 26S ribosomal DNA fragmentsKorsak Koulagenko, Nicolas ; Taminiau, Bernard ; Leclercq, Mathilde et alin Journal of Dairy Science (in press)Milk kefir is produced by fermenting milk in the presence of kefir grains. This beverage has several benefits for human health. The aim of this experiment was to analyze 5 kefir grains (and their products ... [more ▼]Milk kefir is produced by fermenting milk in the presence of kefir grains. This beverage has several benefits for human health. The aim of this experiment was to analyze 5 kefir grains (and their products) using a targeted metagenetic approach. Of the 5 kefir grains analyzed, 1 was purchased in a supermarket, 2 were provided by the Ministry of Agriculture (Namur, Belgium), and 2 were provided by individuals. The metagenetic approach targeted the V1-V3 fragment of the 16S ribosomal (r)DNA for the grains and the resulting beverages at 2 levels of grain incorporation (5 and 10%) to identify the bacterial species population. In contrast, the 26S rDNA pyrosequencing was performed only on kefir grains with the aim of assessing the yeast populations. In parallel, pH measurements were performed on the kefir obtained from the kefir grains using 2 incorporation rates. Regarding the bacterial population, 16S pyrosequencing revealed the presence of 20 main bacterial species, with a dominance of the following: Lactobacillus kefiranofaciens, Lactococcus lactis ssp. cremoris, Gluconobacter frateurii, Lactobacillus kefiri, Acetobacter orientalis, and Acetobacter lovaniensis. An important difference was noticed between the kefir samples: kefir grain purchased from a supermarket (sample E) harbored a much higher proportion of several operational taxonomic units of Lactococcus lactis and Leuconostoc mesenteroides. This sample of grain was macroscopically different from the others in terms of size, apparent cohesion of the grains, structure, and texture, probably associated with a lower level of Lactobacillus kefiranofaciens. The kefir (at an incorporation rate of 5%) produced from this sample of grain was characterized by a lower pH value (4.5) than the others. The other 4 samples of kefir (5%) had pH values above 5. Comparing the kefir grain and the kefir, an increase in the population of Gluconobacter in grain sample B was observed. This was also the case for Acetobacter orientalis in sample D. In relation to 26S pyrosequencing, our study revealed the presence of 3 main yeast species: Naumovozymaspp., Kluyveromyces marxianus, and Kazachastania khefir. For Naumovozyma, further studies are needed to assess the isolation of new species. In conclusion, this study has proved that it is possible to establish the patterns of bacterial and yeast composition of kefir and kefir grain. This was only achieved with the use of high-throughput sequencing techniques. [less ▲]Detailed reference viewed: 9 (2 ULg) Genetic heterogeneity of bovine noroviruses in ItalyDi Martino, Barbara; Di Profio, Federica; Di Felice, Elisabetta et alin Archives of Virology (in press)By screening 104 faecal samples from asymptomatic calves in Italy, bovine norovirus RNA was detected with a prevalence rate of 10.5 % (11/104). A continuous sequence spanning the RdRp region and the 50 ... [more ▼]By screening 104 faecal samples from asymptomatic calves in Italy, bovine norovirus RNA was detected with a prevalence rate of 10.5 % (11/104). A continuous sequence spanning the RdRp region and the 50 end of the capsid gene was generated for 7 of the 11 strains. Upon phylogenetic analysis, five strains were grouped with GIII.2 Newbury2-like viruses, and one strain was grouped with GIII.1 Jena-like noroviruses. Interestingly, one strain (80TE/IT) was genetically related to the GIII.1/Jena/80/De in the RdRp but resembled the GIII.2/Newbury2/76/UK in the capsid gene, suggesting a recombination event occurring in the ORF1/ORF2 junction region. [less ▲]Detailed reference viewed: 11 (3 ULg) Siting Controversies Analysis: Framework and Method for Questioning the ProcedureRossignol, Nicolas ; Parotte, Céline ; Joris, Geoffrey et alin Journal of Risk Research (in press)Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the ... [more ▼]Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the authorities, following a dynamics often quoted as ‘Not In My Back Yard’. Yet contested for its lack of analytical value, NIMBY is still used strategically by actors to qualify citizens as irrational and egoistic. Beyond this labelling, many factors are investigated to understand the dynamics behind siting controversies. In this paper, we focus on the impact of the legal procedure structuring the implantation of windfarms in the Walloon Region (Belgium), and its translations within different decision making processes in specific case studies. To that regard, we consider the legal procedure as a ‘public policy instrument’. It is neither neutral nor natural, and carry values and interests. It organizes inter-personal relations between actors, and is potentially catalyzer of frustrations. In addition, this legal procedure is the object of translations within different contexts, including different actors participating to specific decision making processes. The empirical approach of this paper is based on case studies data and on the use of an innovative methodology called ‘Open Process Workshop’. This methodology consists in a structured workshop with key stakeholders, during which the legal procedure is questioned. Overall, we demonstrate that the focus on the legal procedure - and its translations within different decision making processes - allows systemic analysis providing deep understandings of controversies and reaffirming the interlinks between ‘the social’ and ‘the technical’ in such controversies. In addition, we argue that the methodology used fosters the production of innovative knowledge, mutual understanding and collective learning between the participants. [less ▲]Detailed reference viewed: 43 (12 ULg) Tien Shan Geohazards Database: Landslide susceptibility analysisHavenith, Hans-Balder ; Torgoev, Almazbek ; Schlögel, Romy et alin Geomorphology (in press)This paper is the second part of a new geohazards analysis applied to a large part of the Tien Shan, Central Asia, focused on landslide susceptibility computations that are based on recently compiled ... [more ▼]This paper is the second part of a new geohazards analysis applied to a large part of the Tien Shan, Central Asia, focused on landslide susceptibility computations that are based on recently compiled geographic, geological and geomorphological data. The core data are a digital elevation model, an updated earthquake catalogue, an active fault map as well as a new landslide inventory. The most recently added digital data are a new simplified geological map, an annual precipitation map, as well as river and road network maps that were produced for the Kyrgyz and Tajik parts of the Tien Shan. On the basis of these records we determine landslide densities with respect to morphological (M), geological (G), river distance (R), precipitation (P), earthquake (E) and fault (F) distance factors. Correlations were also established between scarp locations and the slope angle, distance to rivers, curvature. These correlations show that scarps tend to be located on steeper slopes, farther from rivers and on more convex terrain than the entire landslides. On the basis of the landslide density values computed for each class of the aforementioned factors, two landslide susceptibility maps are created according to the Landslide Factor analysis: ... [less ▲]Detailed reference viewed: 8 (0 ULg) Arrêts sur images – usages et pratiques du photogrammeThonon, Jonathan in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)Le photogramme est, au cinéma, la plus petite unité de prise de vue. Image fixe, unité élémentaire du film, le photogramme forme la cellule figée d’un mouvement qui se reconstitue sous l’effet d’un ... [more ▼]Le photogramme est, au cinéma, la plus petite unité de prise de vue. Image fixe, unité élémentaire du film, le photogramme forme la cellule figée d’un mouvement qui se reconstitue sous l’effet d’un défilement réglé (24 photogrammes/seconde) par le dispositif technique du cinéma. Image paradoxale en ce qu’elle reste invisible au spectateur malgré sa force iconique, le photogramme trouve cependant, dans le flux qui le conduit insensiblement à la disparition, certaines zones de visibilité qui en révèlent le caractère à la fois fragile et intensif. Nous allons donc envisager certaines pratiques ou certains usages du photogramme cinématographique, tout en essayant de dégager, au départ de ces pratiques, les éléments d’une théorie du photogramme, que Roland Barthes et Sylvie Pierre appelaient déjà de leurs vœux. Des protos-photogrammes et de leur usage scientifique chez Muybridge et Marey, aux usages artistiques contemporains, en passant par des pratiques publicitaires, promotionnelles ou analytiques, nous allons voir que le photogramme reste un objet singulier. [less ▲]Detailed reference viewed: 49 (2 ULg) Submarine Paleo-earthquake record of the Cinarcik segment of the North Anatolian Fault in the Marmara Sea (Turkey)Drab, Laureen; Hubert, Aurelia ; Carlut, Julie et alin Bulletin Seismological Society of America (in press)The submarine part of the North Anatolian Fault (NAF) in the Marmara Sea is a significant hazard for the city of Istanbul (Turkey). The use of paleoseismological data to provide an accurate seismic risk ... [more ▼]The submarine part of the North Anatolian Fault (NAF) in the Marmara Sea is a significant hazard for the city of Istanbul (Turkey). The use of paleoseismological data to provide an accurate seismic risk assessment for the area is constrained by the fact that the NAF system is submarine near Istanbul; thus a history of paleoearthquakes can be inferred only by using sediment cores. Here a record of turbidites was obtained in two cores and used to reconstruct the earthquake history along a main branch of the NAF, the Cinarcik Segment. Kullenberg core Klg04 (4 m long) was collected during Marmarascarps mission from a berm north of the fault and a second core (Klg03, 3.5 m long) was positioned in the Cinarcik Basin, 3 km south of the fault. Sedimentary sequences in the two cores were correlated using variations in Ca/Ti ratio, which reflect the local aquatic productivity compared with more terrigenous input. The turbidites between the two cores were then classified to distinguish the synchronous ones from the other ones. Radionuclide measurements suggest that the most recent turbidite recorded in both cores was triggered by the M=7.3 1894 earthquake. We conclude that the turbidites are earthquake-generated, based on: 1) their distinctive sedimentological and geochemical signatures, previously described and applied in the Marmara Sea; 2) the correlation of turbidites between cores at berm and basin sites; 3) the match of the most recent turbidites with a 19th century historical earthquake; and 4) the elimination of others processes. Because of its specific geomorphological location, core Klg04 likely records only mass wasting events related to the rupture on the Cinarcik Segment. To date older turbidites, we used 14C and paleomagnetic data to build an OxCal age model with a local reservoir correction (ΔR) of 400±50 yr. The Cinarcik Segment is found to have ruptured in AD1894, AD1509, sometime in the 14th century, AD989, AD740 and in the 5th century and have a mean recurrence interval of rupture between 243 and 396 years. Following the age model obtained we finally used the earthquake record history of the Cinarcik Segment to infer the rupture history of adjacent segments of the North Anatolian Fault during six earthquake cycles over the past 1500 years. [less ▲]Detailed reference viewed: 52 (21 ULg) La sécurité affective chez l'enfant en milieu résidentiel : Des soins du corps au bien être émotionnelAprile, Pauline ; Englebert, Jérôme ; Gauthier, Jean-Marie in Evolution Psychiatrique (in press)Objectives - This review studies the concept of affective security in children living outside of their family environment by a brief exposition of its practical illustration in institution. We want to ... [more ▼]Objectives - This review studies the concept of affective security in children living outside of their family environment by a brief exposition of its practical illustration in institution. We want to show that sufficient affective security can be achieved even in children institutionalized with major attachment difficulties. Method - We will first examine the original meaning of the concept by a theoretical review of its evolution over the years in the literature. Then, we will consider various questions concerning the legitimacy of institutionalization in link with affective security through a case analysis illustrating the issue. We will finally end by mentioning the main practical implications about the optimization of affective security in children institutionalized. Results - It is foremost by the predictable and expected daily acts posed by the professional caregivers in institution that the child may find sufficient affective security, generating emotional well-being and ultimately, an overall adequate development. Discussion – Children early separated from their family home to be placed in residential institution most often suffer from serious difficulties in terms of attachment to others. In this context, the institution has to deal with a specifically challenge: that is, to help the child to (re-)find sufficient internal security to allow him to grow on solid foundations. The institutional life which replaces family life primarily consists of an organizational structure that seeks to make child life as predictable as possible so that it has the necessary daily benchmarks to evolve adequately. Conclusion – In the everyday life in institution, the professionals struggling with children’s attachment disorders constantly try to achieve a right emotional-body balance through their psycho-educational practices with the child deprived of secure attachment strategies. [less ▲]Detailed reference viewed: 156 (13 ULg) Dabigatran Etexilate and Risk of Myocardial Infarction, Other Cardiovascular Events, Major Bleeding, and All-Cause Mortality: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Douxfils, Jonathan; Buckinx, Fanny ; Mullier, Francois et alin Journal of the American Heart Association (in press)BACKGROUND: Signals of an increased risk of myocardial infarction (MI) have been identified with dabigatran etexilate in randomized controlled trials (RCTs). METHODS AND RESULES: We conducted searches of ... [more ▼]BACKGROUND: Signals of an increased risk of myocardial infarction (MI) have been identified with dabigatran etexilate in randomized controlled trials (RCTs). METHODS AND RESULES: We conducted searches of the published literature and a clinical trials registry maintained by the drug manufacturer. Criteria for inclusion in our meta-analysis included all RCTs and the availability of outcome data for MI, other cardiovascular events, major bleeding, and all-cause mortality. Among the 501 unique references identified, 14 RCTs fulfilled the inclusion criteria. Stratification analyses by comparators and doses of dabigatran etexilate were conducted. Peto odds ratio (ORPETO) values using the fixed-effect model (FEM) for MI, other cardiovascular events, major bleeding, and all-cause mortality were 1.34 (95% CI 1.08 to 1.65, P=0.007), 0.93 (95%CI 0.83 to 1.06, P=0.270), 0.88 (95% CI 0.79 to 0.99, P=0.029), and 0.89 (95% CI 0.80 to 1.00, P=0.041). When compared with warfarin, ORPETO values using FEM were 1.41 (95% CI 1.11 to 1.80, P=0.005), 0.94 (95%CI 0.83 to 1.06, P=0.293), 0.85 (95% CI 0.76 to 0.96, P=0.007), and 0.90 (95% CI 0.81 to 1.01, P=0.061), respectively. In RCTs using the 150-mg BID dosage, the ORPETO values using FEM were 1.45 (95% CI 1.11 to 1.91, P=0.007), 0.95 (95% CI 0.82 to 1.09, P=0.423), 0.92 (95% CI 0.81 to 1.05, P=0.228), and 0.88 (95% CI 0.78 to 1.00, P=0.045), respectively. The results of the 110-mg BID dosage were mainly driven by the RE-LY trial. CONCLUSIONS: This meta-analysis provides evidence that dabigatran etexilate is associated with a significantly increased risk of MI. This increased risk should be considered taking into account the overall benefit in terms of major bleeding and all-cause mortality. [less ▲]Detailed reference viewed: 23 (8 ULg) Impact of soft splints on upper limb spasticity in chronic patients with disorders of consciousness: A randomized, single-blind, controlled trialThibaut, Aurore ; Deltombe, Thierry; Wannez, Sarah et alin Brain Injury (in press)Detailed reference viewed: 47 (5 ULg) Conditioning materials with biomacromolecules: composition of the adlayer and influence on cleanabilityToure, Yetioman ; Genet, J. Michel; Dupont-Gillain, C. Christine et alin Journal of Colloid and Interface Science (in press)The influence of substrate hydrophobicity and biomacromolecules (dextran, bovine serum albumin - BSA) adsorption on the cleanability of surfaces soiled by spraying aqueous suspensions of quartz particles ... [more ▼]The influence of substrate hydrophobicity and biomacromolecules (dextran, bovine serum albumin - BSA) adsorption on the cleanability of surfaces soiled by spraying aqueous suspensions of quartz particles (10 to 30 µm size), then dried, was investigated using glass and polystyrene as substrates. The cleanability was evaluated using radial flow cell (RFC). The surface composition was determined by X-ray photoelectron spectroscopy (XPS). The interpretation of XPS data allowed the complexity due to the ubiquitous presence of organic contaminants to be coped with, and the surface composition to be expressed in terms of both the amount of adlayer and the mass concentration of adlayer constituents. When soiled with a suspension of particles in water, glass was much less cleanable than polystyrene, which was attributed to its much lower water contact angle, in agreement with previous observations on starch soil. Dextran was easily desorbed and did not affect the cleanability. The presence of BSA at the interface strongly improved the cleanability of glass while the contact angle did not change appreciably. In contrast, soiling polystyrene with quartz particles suspended in a BSA solution instead of water did not change markedly the cleanability, while the contact angle was much lower and the aggregates of soiling particles were more flat. These observations are explained by the major role of capillary forces developed upon drying, which influence the closeness of the contact between the soiling particles and the substrate and, thereby, the adherence of particles. The capillary forces are proportional to the liquid surface tension and depend in a more complex way on contact angles of the particles and of the substrate. The dependence of cleanability on capillary forces, and in particular on the liquid surface tension, is predominant as compared with its dependence on the size and shape of the soiling aggregates, which influence the efficiency of shear forces exerted by the flowing water upon cleaning. [less ▲]Detailed reference viewed: 40 (19 ULg) Structure and floristic composition of Kibira rainforest, BurundiHakizimana, Dismas; Huynen, Marie-Claude ; Hambuckers, Alain in Tropical Ecology (in press)This paper gives the results of the first census of trees in the 32.15 ha plot in order to provide tree species richness in Kibira rainforest (Burundi). All trees ≥ 10 cm dbh were permanently tagged and ... [more ▼]This paper gives the results of the first census of trees in the 32.15 ha plot in order to provide tree species richness in Kibira rainforest (Burundi). All trees ≥ 10 cm dbh were permanently tagged and their girth measured. The forest structure pattern analysed were diameter at breast height (dbh), basal area, relative dominance, and relative density, Importance Value Index (IVI) and Family Importance Value (FIV). In total, 6504 trees representing 70 species, 67 genera and 37 families were recorded. Tree density was 202 stems/ha, with a basal area of 21.05m²/ha. Seventeen families were represented by a single species each, eleven families were represented by two species each, five families were represented by three species each, and four families were represented by four species each. The most important families in relation to FIV were Euphorbiaceae, Myrtaceae and Araliaceae. Macaranga kilimandscharica, Syzygium guineense and Polyscias fulva were the most important species in relation to IVI. Two tree species were found to be endemic to the Albertine Rift and one species probably endemic to the Albertine Rift. The Shannon-Weiner index (H') and eveness index (J') were respectively 3.18 and 0.75. This study provides a baseline for the management of Kibira National Park. As local communities still depend on forest resources, conservation awareness-raising and education actions have to focus in nearby villages, and growing some fast-growing native trees in the vicinity of the settlement, would be helpful for local communities, this would reduce their dependence on forest resources. [less ▲]Detailed reference viewed: 11 (0 ULg) Breed-specific hematologic reference intervals in healthy adult Dogue de Bordeaux dogsLavoué, Rachel; Geffré, A; Braun, JP et alin Veterinary Clinical Pathology (in press)Detailed reference viewed: 18 (3 ULg) Les défis colossaux auxquels la santé publique va devoir faire face !COUCKE, Philippe in Onco : Revue Multidisciplinaire d'Oncologie (in press)Detailed reference viewed: 43 (18 ULg) Meteorological variation in daily travel behaviour: evidence from revealed preference data from the NetherlandsCreemers, Lieve; Wets, Geert; Cools, Mario in Theoretical & Applied Climatology (in press)This study investigates the meteorological variation in revealed preference travel data. The main objective of this study is to investigate the impact of weather conditions on daily activity participation ... [more ▼]This study investigates the meteorological variation in revealed preference travel data. The main objective of this study is to investigate the impact of weather conditions on daily activity participation (trip motives) and daily modal choices in the Netherlands. To this end, data from the Dutch National Travel Household Survey of 2008 were matched to hourly weather data provided by the Royal Dutch Meteorological Institute and were complemented with thermal indices to indicate the level of thermal comfort and additional variables to indicate the seasonality of the weather conditions. Two multinomial logit–generalised estimation equations (MNL-GEE) models were constructed, one to assess the impact of weather conditions on trip motives and one to assess the effect of weather conditions on modal choice. The modelling results indicate that, depending on the travel attribute of concern, other factors might play a role. Nonetheless, the thermal component, as well as the aesthetical component and the physical component of weather play a significant role. Moreover, the parameter estimates indicate significant differences in the impact of weather conditions when different time scales are considered (e.g. daily versus hourly based). The fact that snow does not play any role at all was unexpected. This finding can be explained by the relatively low occurrence of this weather type in the study area. It is important to consider the effects of weather in travel demand modelling frameworks because this will help to achieve higher accuracy and more realistic traffic forecasts. These will in turn allow policy makers to make better long-term and short-term decisions to achieve various political goals, such as progress towards a sustainable transportation system. Further research in this respect should emphasise the role of weather conditions and activityscheduling attributes. [less ▲]Detailed reference viewed: 70 (20 ULg) Application of Steam Explosion as Pretreatment on Lignocellulosic Material: A ReviewJacquet, Nicolas ; Maniet, Guillaume ; Vanderghem, Caroline et alin Industrial & Engineering Chemistry Research (in press)Steam explosion is a thermo-mechanicochemical pretreatment which allows the breakdown of lignocellulosic structural components by the action of heating, formation of organic acids during the process, and ... [more ▼]Steam explosion is a thermo-mechanicochemical pretreatment which allows the breakdown of lignocellulosic structural components by the action of heating, formation of organic acids during the process, and shearing forces resulting in the expansion of the moisture. Two distinct stages compose the steam-explosion process: vapocracking and explosive decompression which include modification of the material components: hydrolysis of hemicellulosic components (mono- and oligosaccharides released), modification of the chemical structure of lignin, and modification of the cellulose crystallinity index, etc. These effects allow the opening of lignocellulosic structures and influence the enzymatic hydrolysis yield of the material. [less ▲]Detailed reference viewed: 12 (5 ULg) The transition to conservation agriculture : an insularization process towards sustainabilityVankeerberghen, Audrey ; Stassart, Pierre M ; Dannevoye, Bastien in International Journal of Agricultural Sustainability (in press)Detailed reference viewed: 41 (12 ULg) Cervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretionDemoulin, Stéphanie ; SOMJA, Joan ; duray, anaelle et alin OncoImmunology (in press)Detailed reference viewed: 16 (7 ULg) Transnational Ageing and the ‘Zero Generation’: The Role of Moroccan Migrants’ Parents in Care CirculationZickgraf, Caroline in Journal of Ethnic and Migration Studies (in press)This article emphasizes the impacts of international migration on ageing processes and norms within transnational families, and, specifically, analyses the roles of the zero generation, defined as the ... [more ▼]This article emphasizes the impacts of international migration on ageing processes and norms within transnational families, and, specifically, analyses the roles of the zero generation, defined as the parents of first-generation migrants (Nedelcu 2009), both as non-migrant counterparts to their children abroad and as ageing migrants themselves. Transnational caregiving research has demonstrated that for many migrants and their families care arrangements must be negotiated across national borders, yet the agency of transnational older adults has been largely neglected. Based on qualitative fieldwork conducted from 2011 to 2013 in Liège, Belgium and Oujda, Morocco, the present article examines the circulation of care between Moroccan adult migrants and their ageing ascendants. This article exposes the duality of migrants’ ascendants as care givers and recipients, asserting firstly, that receiving care is not synonymous with passivity, and that, secondly, migrants’ ascendants are also the initiators of transnational practices. In both roles, this article underlines mobility as a strategy used by migrants’ parents to maintain family solidarity across national borders, but that this care mobility is limited by macro-level migration policies, here exemplified by the Belgian migration regime. [less ▲]Detailed reference viewed: 15 (3 ULg) Les tourbières sont-elles des réservoirs pour les vecteurs de maladies émergentes ? Evaluation des populations de Culicoides (Diptera: Ceratopogonidae) dans la réserve naturelle des Hautes Fagnes (Belgique)Zimmer, Jean-Yves ; Fagot, Jean ; Smeets, François et alin Documents de la Station scientifique des Hautes-Fagnes (in press)Detailed reference viewed: 41 (15 ULg) Using platelet-rich plasma to treat jumper's knees: Exploring the effect of a second closely-timed infiltrationKaux, Jean-François ; Croisier, Jean-Louis ; Forthomme, Bénédicte et alin Journal of Science and Medicine in Sport (in press)Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of proximal patellar tendinopathy. Although it is possible that a single infiltrative administration may prove ... [more ▼]Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of proximal patellar tendinopathy. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of two or three successive infiltrations. The aim of this study was to evaluate whether two infiltrations of PRP proves more effective than a single treatment. DESIGN: Prospective, randomized and comparative study of level 2. METHODS: Twenty patients suffering from chronic proximal patellar tendinopathy were enrolled into the study and split into two randomized groups (one or two infiltrations of PRP, respectively). The 3-month follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. After 1 year, subjects were contacted to define their functional evolution. RESULTS: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. CONCLUSIONS: The comparison between one or two infiltrations of PRP did not reveal any difference between the two groups at short to mid term. A second closely-timed infiltration of PRP to treat proximal patellar tendinopathies is not necessary to improve the efficacy of this treatment in the short term. [less ▲]Detailed reference viewed: 16 (2 ULg) Singing ability is rooted in vocal-motor control of pitchHutchins, Sean; Larrouy, Pauline ; Peretz, Isabellein Attention, Perception & Psychophysics (in press)The inability to vocally match a pitch can be caused by poor pitch perception or by poor vocal-motor control. Although previous studies have tried to examine the relationship between pitch perception and ... [more ▼]The inability to vocally match a pitch can be caused by poor pitch perception or by poor vocal-motor control. Although previous studies have tried to examine the relationship between pitch perception and vocal production, they have failed to control for the timbre of the target to be matched. In the present study, we compare pitch matching accuracy with an unfamiliar instrument (the slider) and with the voice, designed such that the slider plays back recordings of the participant’s own voice. We also measured pitch accuracy in singing a familiar melody (“Happy Birthday”) to assess the relationship between single pitch matching tasks and melodic singing. Our results showed that participants (all nonmusicians) were significantly better at matching recordings of their own voices with the slider than with their voice, indicating that vocal-motor control is an important limiting factor on singing ability. We also found significant correlations between the ability to sing a melody in tune and vocal pitch matching, but not instrumental pitch matching. Better melodic singers also tended to have higher quality voices (as measured by acoustic variables). These results provide important evidence about the ultimate causes of poor singing ability, and demonstrate that single pitch matching tasks can be useful in measuring general singing abilities. [less ▲]Detailed reference viewed: 21 (5 ULg) Explorer la banque de graines du sol pour mieux comprendre la dynamique de régénération des forêts tropicales africaines (synthèse bibliographique)Douh, Chauvelin ; Daïnou, Kasso ; Loumeto, Jean Joël et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press), 18(4), La banque de graines du sol des forêts denses humides africaines a été très peu étudiée, alors qu’elle pourrait jouer un rôle déterminant dans les cycles sylvigénétiques naturels. Elle pourrait également ... [more ▼]La banque de graines du sol des forêts denses humides africaines a été très peu étudiée, alors qu’elle pourrait jouer un rôle déterminant dans les cycles sylvigénétiques naturels. Elle pourrait également être avantageusement utilisée dans les programmes de restauration, à l’instar de ce qui se fait sur d’autres continents. La présente synthèse bibliographique fait le point sur les connaissances actuelles relatives à la banque de graines du sol, en mettant l’accent sur le continent africain. Elle montre qu’une meilleure caractérisation de la banque de graines du sol des différentes communautés végétales constituerait une contribution notable pour la gestion durable des forêts tropicales d’Afrique. [less ▲]Detailed reference viewed: 65 (18 ULg) Leidenfrost drops: effect of gravityMaquet, Laurent ; Brandenbourger, Martin ; Sobac, Benjamin et alin Europhysics Letters [=EPL] (in press)Detailed reference viewed: 20 (2 ULg) Imaging myeloma and related monoclonal plasma cell disorders: Still room for standard radiography?WITHOFS, Nadia ; Nanni, Cristina; Fanti, Stefano et alin Clin.Translat.Imaging (in press)A majority of multiple myeloma patients present with osteolytic bone lesions that can cause bone pain, fractures or hypercalcaemia. Correct identification of these lesions is important in the initial ... [more ▼]A majority of multiple myeloma patients present with osteolytic bone lesions that can cause bone pain, fractures or hypercalcaemia. Correct identification of these lesions is important in the initial assessment of the disease. Although the radiological skeletal survey is the gold standard to detect bone osteolytic lesions, it may miss small bone lesions or lesions located in the spine or pelvis due to the superimposed images of soft tissues. These limitations propelled newer imaging techniques such as positron emission tomography combined with computed tomography (PET/CT) and magnetic resonance imaging (MRI) in the diagnosis of multiple myeloma. In addition, 18F-fluorodeoxyglucose PET/CT and MRI have prognostic value and can be used to monitor disease. This review discusses the additional value of PET/CT and MRI in the management of MM. [less ▲]Detailed reference viewed: 30 (5 ULg) Per l’edizione di un corpus epistolare plurilinguistico. Note sul rapporto tra grafia e pronuncia in testi volgari italiani del '400 e del '500Valenti, Gianluca in Studi e Problemi di Critica Testuale (in press)Detailed reference viewed: 8 (0 ULg) Effect of coil orientation on strength-duration time constant and I-wave activation with controllable pulse parameter transcranial magnetic stimulationD'Ostilio, Kevin ; Goetz, Stefan; Hannah, Ricci et alin Clinical Neurophysiology (in press)Objective: To compare the strength-duration (S-D) time constants of motor cortex structures activated by current pulses oriented posterior-anterior (PA) or anterior-posterior (AP) across the central ... [more ▼]Objective: To compare the strength-duration (S-D) time constants of motor cortex structures activated by current pulses oriented posterior-anterior (PA) or anterior-posterior (AP) across the central sulcus. Methods: Motor threshold and input–output curve, along with motor evoked potential (MEP) latencies, of first dorsal interosseus were determined at pulse widths of 30, 60, and 120 μs using a controllable pulse parameter (cTMS) device, with the coil oriented PA or AP. These were used to estimate the S-D time constant and we compared with data for responses evoked by cTMS of the ulnar nerve at the elbow. Results: The S-D time constant with PA was shorter than for AP stimulation (230.9 ± 97.2 vs. 294.2 ± 90.9 us; p<0.001). These values were similar to those calculated after stimulation of ulnar nerve (197 ± 47us). MEP latencies to AP, but not PA stimulation were affected by pulse width, showing longer latencies following short duration stimuli. Conclusion: PA and AP stimuli appear to activate the axons of neurons with different time constants. Short duration AP pulses are more selective than longer pulses in recruiting longer latency corticospinal output. [less ▲]Detailed reference viewed: 4 (1 ULg) Congenital jaundice in bovine aborted fetuses: an emerging syndrome in Southern BelgiumDelooz; Mori, M; Petitjean, T et alin Transboundary and Emerging Diseases (in press)Detailed reference viewed: 12 (0 ULg) Dynamic single-cell analysis of Saccharomyces cerevisiae under process perturbation: comparison of different methods for monitoring the intensity of population heterogeneityDelvigne, Frank ; Baert, Jonathan ; Gofflot, Sébastien et alin Journal of Chemical Technology & Biotechnology (in press)BACKGROUND: Single cell biology has attracted a lot of attention these past few years and has led to numerous fundamental results pointing out the heterogeneity of clonal cell populations. In this context ... [more ▼]BACKGROUND: Single cell biology has attracted a lot of attention these past few years and has led to numerous fundamental results pointing out the heterogeneity of clonal cell populations. In this context, microbial phenotypic heterogeneity under bioprocessing conditions needs to be further investigated. In this study, yeast based processes have been investigated by using on-line flow cytometry in combination with a fluorescent transcriptional reporter (GFP) and viability fluorescence tags (propidium iodide, PI). Methods aiming at expressing the dispersion of these fluorescence tags among the yeast populations have been investigated for different bioreactor operating conditions. RESULTS: Yeast viability was determined on the basis of PI uptake. Segregation between PI negative and positive subpopulations could be efficiently quantified on the basis of the mean-to-median ratio or the amplitude of the interquartile range. On the other hand, the same quantification could not be made for the segregation occurring at the level of GFP synthesis. Indeed, when cells were exposed to sub-lethal or mild stresses (such as in scale-down reactors) two GFP subpopulations could be visualized by real-time FC, but quantification by one of the above-mentioned methods was not possible. CONCLUSIONS: Yeast population heterogeneity was observed in representative bioreactor operating conditions. Difficulties for the determination of segregation at the level of GFP synthesis point out the fact that one needs to understand the segregation mechanisms for the applied fluorescent reporters, to judge whether simple mathematical tools may be applied or if more sophisticated computational tools are needed for the quantification of the microbial population segregation. [less ▲]Detailed reference viewed: 54 (29 ULg) Taxonomy, Biostratigraphy and Palaeobiogeography of the Late Tournaisian rugose corals of north-western TurkeyDenayer, Julien in Paläontologische Zeitschrift (in press)Detailed reference viewed: 20 (3 ULg) Where do hybrids come from? Entrepreneurial team heterogeneity as an avenue for the emergence of hybrid organizationsDufays, Frédéric ; Huybrechts, Benjamin in International Small Business Journal (in press)This conceptual paper aims to respond to the poorly addressed question of the emergence of hybrid organizations – i.e. organizations that embrace several institutional logics. It does so by developing a ... [more ▼]This conceptual paper aims to respond to the poorly addressed question of the emergence of hybrid organizations – i.e. organizations that embrace several institutional logics. It does so by developing a model and a set of propositions focusing on the heterogeneity of the entrepreneurial team as a possible driver for hybridity throughout the entrepreneurial process and up to the emergence of a hybrid organization. As contributions to the literatures on (collective) entrepreneurship, imprinting and hybrid organizations, we advance several avenues and conditions under which the heterogeneity of the entrepreneurial team may imprint the entrepreneurial process and lead to the creation of hybrid organizations. Our propositions connect the individual, team and organizational levels and thus advance our understanding of how institutional logics can be combined across different levels of analysis and throughout the stages of an entrepreneurial process. [less ▲]Detailed reference viewed: 31 (2 ULg) Combined use of Ion Mobility and Collision-Induced Dissociation to investigate the opening of disulfide bridges by Electron-Transfer Dissociation in peptides bearing two disulfide bondsMassonnet, Philippe ; Upert, Gregory; Smargiasso, Nicolas et alin Analytical Chemistry (in press)Disulfide bonds are post-translational modifications (PTMs) often found in peptides and proteins. They increase their stability towards enzymatic degradations, and provide the structure and (consequently ... [more ▼]Disulfide bonds are post-translational modifications (PTMs) often found in peptides and proteins. They increase their stability towards enzymatic degradations, and provide the structure and (consequently) the activity of such folded proteins. The characterization of disulfide patterns, i.e the cysteine connectivity, is crucial to achieve a global picture of the active conformation of the protein of interest. Electron Transfer Dissociation (ETD) constitutes a valuable tool to cleave the disulfide bonds in the gas phase, avoiding chemical reduction/alkylation in solution. To characterize the cysteine pairing, the present work proposes (i) to reduce by ETD one of the two disulfide bridges of model peptides , resulting in the opening of the cyclic structures, (ii) to separate the generated species by ion-mobility and, (iii) to characterize the species using CID. Results of this strategy applied to several peptides show different behaviors depending on the connectivity. The loss of SH• radical species, observed for all the peptides, confirms the cleavage of the disulfides during the ETD process. [less ▲]Detailed reference viewed: 22 (6 ULg) Brain metabolic dysfunction in Capgras delusion during Alzheimer’s disease: a positron emission tomography studyJedidi, Haroun ; Daury, Noémy; Rémi, Capa et alin American Journal of Alzheimer's Disease & Other Dementias (in press)Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since ... [more ▼]Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since little is known regarding the neural correlates of Capgras syndrome, the cerebral metabolic pattern of a patient with probable Alzheimer’s disease (AD) and Capgras syndrome was compared with those of 24 healthy elderly subjects and 26 AD patients without delusional syndrome. Compared to the healthy and AD groups, the patient had significant hypometabolism in frontal and posterior midline structures. In light of current neural models of face perception, our patient’s Capgras syndrome may be related to impaired recognition of a familiar face, subserved by the posterior cingulate/precuneus cortex, and impaired reflection about personally relevant knowledge related to a face, subserved by the dorsomedial prefrontal cortex. [less ▲]Detailed reference viewed: 102 (33 ULg) An analogue of Cobham's theorem for graph directed iterated function systemsCharlier, Emilie ; Leroy, Julien ; Rigo, Michel in Advances in Mathematics (in press)Feng and Wang showed that two homogeneous iterated function systems in $\mathbb{R}$ with multiplicatively independent contraction ratios necessarily have different attractors. In this paper, we extend ... [more ▼]Feng and Wang showed that two homogeneous iterated function systems in $\mathbb{R}$ with multiplicatively independent contraction ratios necessarily have different attractors. In this paper, we extend this result to graph directed iterated function systems in $\mathbb{R}^n$ with contraction ratios that are of the form $\frac{1}{\beta}$, for integers $\beta$. By using a result of Boigelot {\em et al.}, this allows us to give a proof of a conjecture of Adamczewski and Bell. In doing so, we link the graph directed iterated function systems to Büchi automata. In particular, this link extends to real numbers $\beta$. We introduce a logical formalism that permits to characterize sets of $\mathbb{R}^n$ whose representations in base $\beta$ are recognized by some Büchi automata. This result depends on the algebraic properties of the base: $\beta$ being a Pisot or a Parry number. The main motivation of this work is to draw a general picture representing the different frameworks where an analogue of Cobham's theorem is known. [less ▲]Detailed reference viewed: 22 (5 ULg) L'Afrique et la science impériale britannique dans une phase de transition: une étude de cas de l'expédition au Congo en 1816 sous la direction de James Kingston TuckeyVandersmissen, Jan in Loxias (in press)Detailed reference viewed: 12 (2 ULg) Tre brevi paragrafi discontinui per una fenomenologia plurale del libro parallelo. Arthur Gordon Pym/Edgar Allan Poe e BachelardCurreri, Luciano in Ermeneutica Letteraria (in press)Detailed reference viewed: 26 (0 ULg) A Double-Blind, Placebo Controlled, Randomized Trial to Assess the Impact of a Monthly Administration of 50,000 IU of Vitamin D3 for 6 Months on Serum Levels of 25-Hydroxyvitamin D in Healthy Young AdultsBrunel, Elodie ; SCHNITZLER, Maryline ; Foidart-Dessalle, Marguerite et alin International Journal of Endocrinology (in press)In this double blind, unicentre, randomized, placebo controlled study, we evaluated the changes in 25-hydroxyvitamin D (25(OH)D) serum levels in 150 young Belgian adults (18–30 years), monthly ... [more ▼]In this double blind, unicentre, randomized, placebo controlled study, we evaluated the changes in 25-hydroxyvitamin D (25(OH)D) serum levels in 150 young Belgian adults (18–30 years), monthly supplemented with 50,000 IU of vitamin D (VTD) or placebo for 6 months, from November 2010 to May 2011. At T0, 30% of the population presented 25(OH)D serum levels below 20 ng/mL. In the VTD-treated group, mean serum levels increased from 21.2 ± 8.2 to 30.6 ± 8.8 ng/mL (𝑃 < 0.001) at T3mo and to 36.0 ± 9.2 ng/mL (𝑃 < 0.001) at T6mo. Despite documented VTD intake, no changes in serum levels were, however, observed in 10% of the treated group. In the placebo group, mean 25(OH)D serum levels decreased from22.8 ± 8.5 to 14.0 ± 6.9 ng/mL at T3mo (𝑃 < 0.001) but returned to values not significantly different from those observed at T0 (23.5 ± 8.6 ng/mL) at T6mo. No difference between serum calcium levels was observed between the groups throughout the study. In conclusion, monthly supplementation with50,000UIofVTDinwinter canwarrant serum25(OH)Dlevels above 20ng/mL in96.2%of thosehealthy young adultswithout inducing unacceptably high 25(OH)D concentration. This supplementation is safe andmay be proposed without 25(OH)D testing. [less ▲]Detailed reference viewed: 61 (12 ULg) L'éveil de la matrix-gla-protéine sonnera le glas des calcifications vasculairesDELANAYE, Pierre ; Liabeuf, Sophie; BOUQUEGNEAU, Antoine et alin Néphrologie & Thérapeutique (in press)La matrix-gla-protéine (MGP) est principalement sécrétée par les chondrocytes et les cellules musculaires lisses des parois vasculaires. Son rôle est d’inhiber localement le développement des ... [more ▼]La matrix-gla-protéine (MGP) est principalement sécrétée par les chondrocytes et les cellules musculaires lisses des parois vasculaires. Son rôle est d’inhiber localement le développement des calcifications vasculaires. MGP doit bénéficier de deux processus post-transcriptionnels avant d’être pleinement active : une phosphorylation de résidus sérine et une carboxylation de résidus glutamate. Cette carboxylation ne peut se faire qu’en présence de quantité suffisante de vitamine K. Plusieurs formes de MGP circulent donc dans le plasma, certaines étant totalement inactives (la MGP déphosphorylée et décarboxylée), d’autres possédant une activité biologique variable en fonction du nombre de sites carboxylés ou phosphorylés. Il existe un lien théorique étroit entre MGP, vitamine K, calcifications vasculaires et maladies cardiovasculaires et ce, particulièrement chez les patients souffrant d’insuffisance rénale chronique, a fortiori s’ils sont dialysés. Si l’existence de ce lien a été démontrée via de nombreuses et solides données fondamentales, les données cliniques restent, à ce jour, observationnelles et doivent donc être interprétées avec prudence. Mesurer une fraction de MGP dans le plasma pour estimer le degré de calcification d’un patient donné n’est pas encore d’actualité . La forme inactive pourrait être utile pour juger des réserves en vitamine K au niveau vasculaire. Dans cet article de revue, nous reviendrons sur les bases théoriques du rôle de MGP dans le processus de calcification vasculaire, sur le défi analytique que représente sa détermination dans le plasma, ainsi que sur les liens entre MGP, vitamine K et calcifications vasculaires en population géne´ rale et chez les patients insuffisants rénaux. [less ▲]Detailed reference viewed: 19 (2 ULg) Rugose corals across the Devonian-Carboniferous boundary in NW TurkeyDenayer, Julien in Acta Palaeontologica Polonica (in press)Detailed reference viewed: 24 (4 ULg) La pollution lumineuse, entre écologie et santéJEDIDI, Haroun ; DEPIERREUX, Frédérique ; JEDIDI, Zayd et alin Revue Médicale de Liège (in press)Light pollution is defined as the abnormal and disturbing presence of light and its adverse consequences on flora, faunae, ecosystems and its suspected or proven effects on human health. Light pollution ... [more ▼]Light pollution is defined as the abnormal and disturbing presence of light and its adverse consequences on flora, faunae, ecosystems and its suspected or proven effects on human health. Light pollution is a quite recent and increasing phenomenon within our society and it leads to a major environmental damage, obviously near wildlife, but also on human health (cancers, obesity, fatigue, depression...). The solutions to this problem are however simple, efficient and de facto inexpensive and involving a substantial energy saving. [less ▲]Detailed reference viewed: 16 (10 ULg) Enhanced exploratory activity in woodlice exposed to random visuo-tactile patternsAnselme, Patrick in Learning & Motivation (in press)In birds and mammals, randomness is known to have excitatory effects on exploratory behavior, but this phenomenon has not extensively been studied in invertebrates. Four experiments examined the ... [more ▼]In birds and mammals, randomness is known to have excitatory effects on exploratory behavior, but this phenomenon has not extensively been studied in invertebrates. Four experiments examined the propensity of woodlice (Porcellio scaber) to choose between the exploration of an environment composed of random visuo-tactile patterns and the exploration of an environment composed of regular visuo-tactile patterns. Rearing-up behavior and distance traveled were measured to determine (i) woodlice’s reactivity to a forced exposure to random or regular patterns, (ii) the effect of random and regular patterns on exploratory choice, (iii) the effect of random and regular patterns on exploratory choice in preexposed animals, and (iv) the effect of a shelter available in the less explored environment on exploratory choice. The results suggest that random visuo-tactile patterns have an excitatory effect on the exploratory behavior of woodlice and that this effect develops more rapidly if the woodlice were initially preexposed to those patterns. They also suggest that exploration is related to the search for better habitat conditions because the presence of a shelter abolishes that behavior. [less ▲]Detailed reference viewed: 18 (0 ULg) Island floras are not necessarily more species-poor than continental ones.Patiño, J.; Solymos, P.; Carine, M.A. et alin Journal of Biogeography (in press)Detailed reference viewed: 21 (0 ULg) On the accuracy of adults’ auditory perception of normophonic and dysphonic children’s personality.Verduyckt, Ingrid; Remacle, Marc; Morsomme, Dominique in Logopedics, Phoniatrics, Vocology (in press)We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (N=57) were asked to infer the personality of normophonic (NP ... [more ▼]We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (N=57) were asked to infer the personality of normophonic (NP) children and children with VFN (N=10) on the basis of vowels and sentences. The auditory inferred profiles were compared to the actual personality of NP and VFN children. Positive and partly accurate inferences of VFN children’s personality were made on the basis of connected speech, while sustained vowels yielded negative and inaccurate inferences of personality traits of children with VFN. Dysphonic voice quality, as defined by the overall severity of vocal abnormality, conveyed inaccurate and low degrees of Extraversion. This effect was counterbalanced in connected speech by faster speaking rate that accurately conveyed higher degrees of Extraversion, a characteristic trait of VFN children’s actual personality. [less ▲]Detailed reference viewed: 20 (0 ULg) Long term-cultured and cryopreserved primordial germ cells from various chicken breeds retain high proliferative potential and gonadal colonisation competencyTonus, Céline ; Cloquette, Karine; Ectors, Fabien et alin Reproduction, Fertility and Development (in press)Detailed reference viewed: 61 (28 ULg) Maqriziana XIV: Al-Maqrīzī’s Last Opus (Al-Ḫabar ʿan al-Bašar) and Its Significance for the History of IslamBauden, Frédéric in Journal of the Royal Asiatic Society (in press)Detailed reference viewed: 71 (15 ULg) A European survey on attitudes towards pain and end-of-life issues in locked-in syndromeDemertzi, Athina ; Jox, Ralf J; Racine, Eric et alin Brain Injury (in press)Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in ... [more ▼]Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in syndrome. Methods: Close-ended survey among conference attendees from 33 European countries. Analysis included chi-square tests and logistic regressions. Results: From the 3332 respondents (33% physicians, 18% other clinicians, 49% other professions; 47% religious), 90% agreed that patients with locked-in syndrome can feel pain. The majority (75%) disagreed with treatment withdrawal, but 56% did not wish to be kept alive if they imagined themselves in this condition (p50.001). Religious and southern Europeans opposed to treatment withdrawal more often than non-religious (p50.001) and participants from the North (p¼0.001). When the locked-in syndrome was compared to disorders of consciousness, more respondents endorsed that being in a chronic locked-in syndrome was worse than being in a vegetative state or minimally conscious state for patients (59%) than they thought for families (40%, p50.001). Conclusions: Personal characteristics mediate opinions about locked-in syndrome. The dissociation between personal preferences and general opinions underlie the difference in perspective in disability. Ethical responses to dilemmas involving patients with locked-in syndrome should consider the diverging ethical attitudes of stakeholders. [less ▲]Detailed reference viewed: 153 (8 ULg) Compte rendu de G. TOUSSAINT, Kreuz und Knochen. Reliquien zur Zeit der Kreuzzüge, Berlin, 2011.George, Philippe in Cahiers de Civilisation Médiévale (in press)Detailed reference viewed: 23 (2 ULg) The Herschel view of the nebula around the luminous blue variable star AG CarinaeVamvatira-Nakou, Chloi ; Hutsemekers, Damien ; Royer, P. et alin Astronomy and Astrophysics (in press)Far-infrared Herschel PACS imaging and spectroscopic observations of the nebula around the luminous blue variable (LBV) star AG Car have been obtained along with optical imaging in the Halpha+[NII] filter ... [more ▼]Far-infrared Herschel PACS imaging and spectroscopic observations of the nebula around the luminous blue variable (LBV) star AG Car have been obtained along with optical imaging in the Halpha+[NII] filter. In the infrared light, the nebula appears as a clumpy ring shell that extends up to 1.2 pc with an inner radius of 0.4 pc. It coincides with the Halpha nebula, but extends further out. Dust modeling of the nebula was performed and indicates the presence of large grains. The dust mass is estimated to be ~ 0.2 Msun. The infrared spectrum of the nebula consists of forbidden emission lines over a dust continuum. Apart from ionized gas, these lines also indicate the existence of neutral gas in a photodissociation region that surrounds the ionized region. The abundance ratios point towards enrichment by processed material. The total mass of the nebula ejected from the central star amounts to ~ 15 Msun, assuming a dust-to-gas ratio typical of LBVs. The abundances and the mass-loss rate were used to constrain the evolutionary path of the central star and the epoch at which the nebula was ejected, with the help of available evolutionary models. This suggests an ejection during a cool LBV phase for a star of ~ 55 Msun with little rotation. [less ▲]Detailed reference viewed: 17 (8 ULg) Tien Shan geohazards database: Earthquakes and landslidesHavenith, Hans-Balder ; Strom, Alexander; Torgoev, Isakbek et alin Geomorphology (in press)In this paper we present new and review already existing landslide and earthquake data for a large part of the Tien Shan, Central Asia. For the same area, only partial databases for sub-regions have been ... [more ▼]In this paper we present new and review already existing landslide and earthquake data for a large part of the Tien Shan, Central Asia. For the same area, only partial databases for sub-regions have been presented previously. They were compiled and new data were added to fill the gaps between the databases. Major new inputs are products of the Central Asia Seismic Risk Initiative (CASRI): a tentative digital map of active faults (even with indication of characteristic or possible maximum magnitude) and the earthquake catalogue of Central Asia until 2009 that was now updated with USGS data (to May 2014). The new compiled landslide inventory contains existing records of 1600 previously mapped mass movements and more than 1800 new landslide data. Considering presently available seismo-tectonic and landslide data, a target region of 1200 km (E–W) by 600 km (N–S) was defined for the production of more or less continuous geohazards information. This target region includes the entire Kyrgyz Tien Shan, the South-Western Tien Shan in Tajikistan, the Fergana Basin (Kyrgyzstan, Tajikistan and Uzbekistan) as well as the Western part in Uzbekistan, the North-Easternmost part in Kazakhstan and a small part of the Eastern Chinese Tien Shan (for the zones outside Kyrgyzstan and Tajikistan, only limited information was available and compiled)... [less ▲]Detailed reference viewed: 13 (0 ULg) Biodistribution and radiation dosimetry for the novel SV2A radiotracer [18F]UCB-H: Firstin- human study.Bretin, Florian ; Bahri, Mohamed Ali ; BERNARD, Claire et alin Molecular Imaging & Biology (in press)Abstract- [18F]UCB-H is a novel radiotracer with a high affinity for SV2A, a protein expressed in synaptic vesicles. SV2A is the binding site of levetiracetam, a “first in class” antiepileptic drug with a ... [more ▼]Abstract- [18F]UCB-H is a novel radiotracer with a high affinity for SV2A, a protein expressed in synaptic vesicles. SV2A is the binding site of levetiracetam, a “first in class” antiepileptic drug with a distinct but still poorly understood mechanism of action. The objective of this study was to determine the biodistribution and radiation dosimetry of [18F]UCB-H in a human clinical trial and to establish injection limits according to biomedical research guidelines. Additionally, the clinical radiation dosimetry results were compared to estimations in previously published preclinical data. Dynamic whole body PET/CT imaging was performed over approximately 110 minutes on five healthy male volunteers after injection of 144.5 ± 7.1 MBq (range, 139.1 – 156.5 MBq) of [18F]UCB-H. Major organs were delineated on CT images and time-activity curves were obtained from co-registered dynamic PET emission scans. Time-integrated activity coefficients were calculated as area under the curve using trapezoidal numerical integration. Urinary excretion data based on PET-activities including voiding was simulated using the dynamic bladder module of OLINDA/EXM. The radiation dosimetry was calculated using OLINDA/EXM. The effective dose to the OLINDA/EXM 70 kg standard male was 1.54E-02 ± 6.84E-04 mSv/MBq, with urinary bladder wall, gallbladder wall and the liver receiving the highest absorbed dose. The brain, the tracer’s main organ of interest, received an absorbed dose of 1.89E-02 ± 2.32E-03 mGy/MBq. This first human dosimetry study of [18F]UCB-H indicated that the tracer shows similar radiation burdens to widely used common clinical tracers. Single injections of at maximum 672 MBq for USA practice and 649 MBq for European practice keep radiation exposure below recommended limits. Recently published preclinical dosimetry data extrapolated from mice provided satisfactory prediction of total body and effective dose, but showed significant differences in organ absorbed doses compared to human data. [less ▲]Detailed reference viewed: 57 (17 ULg) Do aphids actively search for ant partners?Fischer, Christophe ; Vanderplanck, Maryse; Lognay, Georges et alin Insect Science (in press)The aphid–ant mutualistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is ... [more ▼]The aphid–ant mutualistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is largely assumed that ants actively search for their mutualistic partners namely using volatile cues; whether winged aphids (i.e. aphids’ most mobile form) are able to select ant-frequented areas had not been investigated so far. Ant-frequented sites would indeed offer several advantages for these aphids including a lower predation pressure through ant presence and enhanced chances of establishing mutuaslistic interactions with neighbour ant colonies. In the field, aphid colonies are often observed in higher densities around ant nests, which is probably linked to a better survival ensured by ants’ services. Nevertheless, this could also result from a preferential establishment of winged aphids in ant-frequented areas. We tested this last hypothesis through different ethological assays and show that the facultative myrmecophilous black bean aphid, Aphis fabae L., does not orientate its search for a host plant preferentially towards ant-frequented plants. However our results suggest that ants reduce the number of winged aphids leaving the newly colonized plant. Thus, ants involved in facultative myrmecophilous interactions with aphids appear to contribute to structure aphid populations in the field by ensuring a better establishment and survival of newly established colonies rather than by inducing a deliberate plant selection by aphid partners based on the proximity of ant colonies. [less ▲]Detailed reference viewed: 42 (14 ULg) Characterizing activity sequences using Profile Hidden Markov ModelsLiu, Feng; Janssens, Davy; Cui, JianXun et alin Expert Systems with Applications (in press)In literature, activity sequences, generated from activity-travel diaries, have been analyzed and classified into clusters based on the composition and ordering of the activities using Sequence Alignment ... [more ▼]In literature, activity sequences, generated from activity-travel diaries, have been analyzed and classified into clusters based on the composition and ordering of the activities using Sequence Alignment Methods (SAM). However, using these methods, only the frequent activities in each cluster are extracted and qualitatively described; the infrequent activities and their related travel episodes are disregarded. Thus, to quantify the occurrence probabilities of all the daily activities as well as their sequential orders, we develop a novel process to build multiple alignments of the sequences and subsequently derive profile Hidden Markov Models (pHMMs). This process consists of 4 major steps. First, activity sequences are clustered based on a pre-defined scheme. The frequent activities along with their sequential orders are then identified in each cluster, and they are subsequently used as a template to guide the construction of a multiple alignment of the cluster of sequences. Finally, a pHMM is employed to convert the multiple alignment into a position-specific scoring system, representing the probability of each frequent activity at each important position of the alignment as well as the probabilities of both insertion and deletion of infrequent activities. By applying the derived pHMMs to a set of activity-travel diaries collected in Belgium as well as a group of mobile phone call location data recorded in Switzerland, the potential and effectiveness of the models in capturing the sequential features of each cluster and distinguishing them from those of other clusters, are demonstrated. The proposed method can also be utilized to improve activity-based transportation model validation and travel survey designs. Furthermore, it offers a wide application in characterizing a group of any related sequences, particularly sequences varying in length and with a high frequency of short sequences that are typically present in human behavior. [less ▲]Detailed reference viewed: 18 (2 ULg) A multi-scale magnetotail reconnection event at Saturn and associated ows: Cassini/UVIS observationsRadioti, Aikaterini ; Grodent, Denis ; Jia, X. et alin Icarus (in press)Detailed reference viewed: 32 (16 ULg)