References of "Scientific journals"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 901 to 1000 of 51971     5 6 7 8 9 10 11 12 13 14 15     Imagerie métabolique en oncologie thoraciqueDUYSINX, Bernard ; HUSTINX, Roland in EMC Pneumologie (2015), 12(2), Detailed reference viewed: 11 (2 ULg) L’anéantissement des donations : questions de droit international privéWautelet, Patrick ; Fongaro, Ericin Revue de planification patrimoniale belge et internationale (2015), 2(1), 39-64Avec le développement d'une véritable pratique transfrontière de la planification successorale, les questions de droit international privé entourant les donations ont beaucoup retenu l'attention ces ... [more ▼]Avec le développement d'une véritable pratique transfrontière de la planification successorale, les questions de droit international privé entourant les donations ont beaucoup retenu l'attention ces dernières années. Cet intérêt renouvelé pour un sujet classique a permis d'élucider le statut pour le moins complexe de la donation qui présente une dimension internationale. On a toutefois peu évoqué les difficultés que peuvent susciter la fragilité des donations : institution de droit civil aux contours pour le moins polymorphes, la donation est entourée de nombreuses limitations et obstacles qui ont pour objectif de conjurer les risques que peut faire naître, tant pour le donateur, sa famille que pour ses créanciers, cet acte particulier d'appauvrissement sans contrepartie. Le régime contemporain des donations est fondé sur une série de règles et mécanismes qui permettent de remettre en question la libéralité. Tantôt c'est la capacité d'une des parties (à donner ou à recevoir) qui fait l'objet de dispositions dérogatoires au droit commun, tantôt c'est le consentement du donateur qui suscite l'application d'une règle spéciale, tantôt encore des exigences particulières sont posées à propos des formes que doit revêtir une donation. Ces règles complexes, qui nourrissent un contentieux fourni, sont autant d'obstacles qui peuvent être posés au plein accomplissement des donations. Elles conduisent parfois à la révocation de la donation, qui peut produire ses effets ex nunc ou dans certains cas de façon rétroactive. Dans d'autres situations, la donation est annulée et dès lors considérée comme n'ayant jamais existé. Une donation peut également faire l'objet d'une déclaration ou encore être frappée de caducité ou de déchéance. Ces questions sont abordées dans la présente contribution sous l'angle du droit international privé belge et français, en mettant l'accent tant sur les différences que sur les simillitudes entre ces droits. [less ▲]Detailed reference viewed: 33 (4 ULg) First do not harmJamoulle, Marc in Journal of Mid-life Health (2015), 6(2), 51-52commentary on Kalra B, Malik S. Quaternary prevention and menopause. J Midlife Health 2014;5:53-4.Detailed reference viewed: 14 (1 ULg) La défense belge dans le futurDumoulin, André in Revue de Défense nationale (2015), (4), Analyse de l'évolution récente de l'armée belge avec quelques propositions relatives à son avenir dans le cadre de la préparation d'un nouveau plan stratégique à l'horizon 2030Detailed reference viewed: 32 (7 ULg) L’Affaire Édouard Descamps à la Cour de La Haye en 1921. Un recul international de la Belgique ?Genin, Vincent in Revue Générale (2015), 3/4(mars-avril), 35-42Detailed reference viewed: 37 (0 ULg) Choix de la première contraceptionBELIARD, Aude in Réalités en Gynécologie-Obstétrique (2015), vol 176Proposer une contraception adéquate chez les adolescentes est primordial afin d’éviter toute grossesse non désirée. Il est indispensable de conseiller les jeunes filles de façon appropriée pour améliorer ... [more ▼]Proposer une contraception adéquate chez les adolescentes est primordial afin d’éviter toute grossesse non désirée. Il est indispensable de conseiller les jeunes filles de façon appropriée pour améliorer l’observance et leur expliquer les effets secondaires éventuels pour éviter les échecs de contraception. Le risque d’infection sexuellement transmissible n’est pas négligeable et il faut insister sur l’intérêt de l’usage du préservatif. La contraception combinée œstroprogestative orale présente aussi des avantages non contraceptifs comme l’amélioration de la dysménorrhée entre autre. Le choix du contraceptif hormonal doit tenir compte des facteurs de risque personnels et familiaux et il est nécessaire de reprogrammer une consultation ultérieure afin d’adapter la contraception si nécessaire [less ▲]Detailed reference viewed: 51 (2 ULg) Climatic risk assessment to improve nitrogen fertilisation recommendations : A strategic crop model-based approachDumont, Benjamin ; Basso, Bruno; Bodson, Bernard et alin European Journal of Agronomy (2015), 65(10-17), Within the context of nitrogen (N) management, since 1950, with the rapid intensification of agriculture, farmers have often applied much larger fertiliser quantities than what was required to reach the ... [more ▼]Within the context of nitrogen (N) management, since 1950, with the rapid intensification of agriculture, farmers have often applied much larger fertiliser quantities than what was required to reach the yield potential. However, to prevent pollution of surface and groundwater induced by nitrates, The European Community launched The European Nitrates Directive 91/6/76/EEC. In 2002, in Wallonia (Belgium), the Nitrates Directive has been transposed under the Sustainable Nitrogen Management in Agriculture Program (PGDA), with the aim of maintaining productivity and revenue for the country’s farmers, while reducing the environmental impact of excessive N application. A feasible approach for addressing climatic uncertainty lies in the use of crop models such as the one commonly known as STICS (simulateur multidisciplinaire pour les cultures standard). These models allow the impact on crops of the interaction between cropping systems and climatic records to be assessed. Comprehensive historical climatic records are rare, however, and therefore the yield distribution values obtained using such an approach can be discontinuous. In order to obtain better and more detailed yield distribution information, the use of a high number of stochastically generated climate time series was proposed, relying on the LARS-Weather Generator. The study focused on the interactions between varying N practices and climatic conditions. Historically and currently, Belgian farmers apply 180 kg N ha−1, split into three equal fractions applied at the tillering, stem elongation and flag-leaf stages. This study analysed the effectiveness of this treatment in detail, comparing it to similar practices where only the N rates applied at the flag-leaf stage were modified. Three types of farmer decision-making were analysed. The first related to the choice of N strategy for maximising yield, the second to obtaining the highest net revenue, and the third to reduce the environmental impact of potential N leaching, which carries the likelihood of taxation if inappropriate N rates are applied. The results showed reduced discontinuity in the yield distribution values thus obtained. In general, the modulation of N levels to accord with current farmer practices showed considerable asymmetry. In other words, these practices maximised the probability of achieving yields that were at least superior to the mean of the distribution values, thus reducing risk for the farmers. The practice based on applying the highest amounts (60–60–100 kg N ha−1) produced the best yield distribution results. When simple economical criteria were computed, the 60–60–80 kg N ha−1 protocol was found to be optimal for 80–90% of the time. There were no statistical differences, however, between this practice and Belgian farmers’ current practice. When the taxation linked to a high level of potentially leachable N remaining in the soil after harvest was considered, this methodology clearly showed that, in 3 years out of 4, 30 kg N ha−1 could systematically be saved in comparison with the usual practice. [less ▲]Detailed reference viewed: 35 (5 ULg) L'Union européenne et le testament conjonctif : la fin des incertitudes?Wautelet, Patrick in Droit & Patrimoine (2015), 246(40-47), Le sort des testaments conjonctifs dans les relations internationales privées a de longue date suscité des questions. Cette contribution s'interroge sur l'apport du Règlement successions (650/2012) : ce ... [more ▼]Le sort des testaments conjonctifs dans les relations internationales privées a de longue date suscité des questions. Cette contribution s'interroge sur l'apport du Règlement successions (650/2012) : ce Règlement permet-il de garantir la circulation d'un testament conjonctif entre Etats membres? [less ▲]Detailed reference viewed: 16 (0 ULg) Comparer et articuler les droits. L'exemple du démariage en 2015Wautelet, Patrick in Droit de la famille (2015), 20(4), 63-66Cette communication dresse un tableau succincts de l'état du droit comparé du divorce en Europe. L'analyse de droit comparé sert d'appui à une mise en perspective du droit international privé du divorce.Detailed reference viewed: 44 (1 ULg) Reforming Belgium’s federalism: Comparing the views of MPs and votersReuchamps, Min; Sinardet, Dave; Dodeigne, Jérémy et alin Government and Opposition : An International Journal of Comparative Politics (2015)Detailed reference viewed: 17 (4 ULg) Extensions du concept de fonctionBair, Jacques ; Henry, Valérie in Tangente Hors Série (2015), (56), 41Extensions modernes du concept de fonction Comme la plupart des concepts mathématiques, celui de fonction s’est transformé progressivement pour devenir ce qui nous en est enseigné aujourd’hui. Il évolue ... [more ▼]Extensions modernes du concept de fonction Comme la plupart des concepts mathématiques, celui de fonction s’est transformé progressivement pour devenir ce qui nous en est enseigné aujourd’hui. Il évolue encore de nos jours : il est toujours plus général, mais également plus abstrait et sophistiqué. Nous donnons ici un petit aperçu intuitif de quelques-unes de ses généralisations modernes. [less ▲]Detailed reference viewed: 20 (1 ULg) Transhumanisme : un imaginaire de l’exploitation ?Absil, Gaëtan ; Govers, Patrick in Salut & Fraternité (2015), 89Vaincre la mort semble un horizon plausible du transhumanisme : l’utilisation des sciences et des technologies pour améliorer la condition humaine et en exclure le handicap, la maladie, le vieillissement ... [more ▼]Vaincre la mort semble un horizon plausible du transhumanisme : l’utilisation des sciences et des technologies pour améliorer la condition humaine et en exclure le handicap, la maladie, le vieillissement et la mort. L’immortalité relève des instances imaginaires, matérielles et des relations sociales. Elle relève d’une anthropologie du corps et d’une analyse de la technique comme « recherche du moyen le plus efficace dans tous les domaines. » [less ▲]Detailed reference viewed: 76 (3 ULg) Comparative effectiveness of silvicultural interventions for increasing timber production and sustaining conservation values in natural tropical production forests. A systematic review protocolPetrokofsky, Gillian; Sist, Plinio; Blanc, Lilian et alin Environmental Evidence (2015), 4(8), Background: Currently, about 400 million hectares of tropical moist forests worldwide are designated production forests, about a quarter of which are managed by rural communities and indigenous peoples ... [more ▼]Background: Currently, about 400 million hectares of tropical moist forests worldwide are designated production forests, about a quarter of which are managed by rural communities and indigenous peoples. There has been a gradual impoverishment of forest resources inside selectively logged forests in which the volume of timber extracted over the first cutting cycle was mostly from large, old trees that matured over a century or more and grew in the absence of strong anthropological pressures. In forests now being logged for a second and third time, that volume has not been reconstituted due in part to the lack of implementation of post-logging silvicultural treatments. This depletion of timber stocks renders the degraded forests prone to conversion to other land uses. Although it is essential to preserve undisturbed primary forests through the creation of protected areas, these areas alone will not be able to ensure the conservation of all species on a pan-tropical scale, for social, economic and political reasons. The conservation of tropical forests of tomorrow will mostly take place within human-modified (logged, domesticated) forests. In this context, silvicultural interventions are considered by many tropical foresters and forest ecologists as tools capable of effectively conserving tropical forest biodiversity and ecosystem services while stimulating forest production. This systematic review aims to assess past and current evidence of the impact of silviculture on tropical forests and to identify silvicultural practices appropriate for the current conditions in the forests and forestry sectors of the Congo Basin, Amazonia and Southeast Asia. Methods: This systematic review will undertake an extensive search of literature to assess the relative effectiveness of different silvicultural interventions on timber production and the conservation value of forests, and to determine whether there is a relationship between sustainability of timber harvesting and the maintenance/conservation of other ecosystem services and biodiversity in production forests. Data will be extracted for meta-analysis of at least sub-sets of the review questions. Findings are expected to help inform policy and develop evidence-based practice guidelines on silvicultural practices in tropical forests. [less ▲]Detailed reference viewed: 28 (4 ULg) STENOSE AORTIQUE SEVERE ASYMPTOMATIQUE A FRACTION D'EJECTION VENTRICULAIRE GAUCHE PRESERVEE. EVALUATION A L'EFFORT: QUELS RESULTATS ET QUELLES DECISIONS?BENSAHI, I; ELFHAL, A; MAGNE, Julien et alin Annales de Cardiologie et d'Angeiologie (2015), 64(2), 100-108Detailed reference viewed: 24 (4 ULg) Effets de la modernisation de tannerie sur l’impact de ses activités sur la qualité des eaux : cas de la tannerie de Maradi au NigerSaidou, H.; Laminou Manzo, O.; Ozer, Pierre et alin Research Inventy: International Journal Of Engineering And Science (2015), 5(4), 30-38The modernization of the tannery of Maradi had intervened in 2009 with the introduction of the process of tanning in the chromium. We estimated the influence of this change of operating process through an ... [more ▼]The modernization of the tannery of Maradi had intervened in 2009 with the introduction of the process of tanning in the chromium. We estimated the influence of this change of operating process through an evaluation of the impact characteristics evolution of the solid and liquid discharges of this tannery on water. It stands out that the modernization of the tannery activities had more or less significant effects on these environment elements. We noted a relative improvement of the quality of underground waters illustrated by the regression of the content in chloride and nitrates rates stabilization. While the content in chromium evolved in a significant way as well as the pH. However, all the four above parameters remain below WHO standards. By cons, this modernization has almost not influenced the impact on the quality of surface waters. The values of BOD and COD have continued to rise despite the installation of a treatment system. Thus this surface water, including the pond, proved to be a major public health risk for domestic and agricultural use and is also a source of air pollution. [less ▲]Detailed reference viewed: 45 (1 ULg) Financement de la santé et recouvrement des coûts : le lourd fardeau des ménages congolais. Résultats des comptes nationaux de la santé.Manzambi Kuwekita, Joseph ; Eloko Eya Matangelo, Gérard; Bruyère, Olivier et alin Journal d’Épidémiologie et de Santé Publique (2015), 15(Mars 2015), 15-27This study examines the share and allocation of household expenditure in health financing, as presented by the National Health Account figures. These figures are based on a national survey carried out in ... [more ▼]This study examines the share and allocation of household expenditure in health financing, as presented by the National Health Account figures. These figures are based on a national survey carried out in 2010 among 11,000 households, 2,200 people living with HIV/AIDS, 183 institutions, 42 mutual funds, 18 companies and using the balance sheets of 1,300 companies. Total household health expenditure per capita per year amounted to U.S. 4.50. Routine health expenditure is covered by the households (40%) and international cooperation (45%) through direct payment without cost sharing (93.7%). A hospital stay is warranted in case of nutritional deficiencies (34%), malaria (12%) and mental disorders (10%). 82% of outpatient care is related to malaria (71%) and mental disorders (12.5 %). In conclusion, the observation that 71.58% of hospitals expenditure, 96.49% of ambulatory care centres expenditure, 98.48% of medical and diagnosis laboratories expenditure, 72.42% of pharmacies expenditures come from households’ out of pocket expenses calls for the establishment of solidarity mechanisms in the health sector. Outpatient malaria care consumes as much as 71% of household expenditure, and we therefore need to strengthen prevention, treatment and focus on monitoring progress. The fact that nutritional deficiencies are the leading cause of people seeking hospital care suggests that efforts are needed to improve their living conditions of households. Mental disorders are the third leading cause of hospital recourse and this pathology should therefore be included in the minimum and supplementary package of activities. [less ▲]Detailed reference viewed: 53 (13 ULg) Primary prevention of peri-implantitis: Managing peri-implant mucositisJepsen, Søren; Berglundh, Tord; Genco, Robert et alin Journal of Clinical Periodontology (2015), 42(S16), 152157Abstract AIMS: Over the past decades, the placement of dental implants has become a routine procedure in the oral rehabilitation of fully and partially edentulous patients. However, the number of patients ... [more ▼]Abstract AIMS: Over the past decades, the placement of dental implants has become a routine procedure in the oral rehabilitation of fully and partially edentulous patients. However, the number of patients/implants affected by peri-implant diseases is increasing. As there are--in contrast to periodontitis--at present no established and predictable concepts for the treatment of peri-implantitis, primary prevention is of key importance. The management of peri-implant mucositis is considered as a preventive measure for the onset of peri-implantitis. Therefore, the remit of this working group was to assess the prevalence of peri-implant diseases, as well as risks for peri-implant mucositis and to evaluate measures for the management of peri-implant mucositis. METHODS: Discussions were informed by four systematic reviews on the current epidemiology of peri-implant diseases, on potential risks contributing to the development of peri-implant mucositis, and on the effect of patient and of professionally administered measures to manage peri-implant mucositis. This consensus report is based on the outcomes of these systematic reviews and on the expert opinion of the participants. RESULTS: Key findings included: (i) meta-analysis estimated a weighted mean prevalence for peri-implant mucositis of 43% (CI: 32-54%) and for peri-implantitis of 22% (CI: 14-30%); (ii) bleeding on probing is considered as key clinical measure to distinguish between peri-implant health and disease; (iii) lack of regular supportive therapy in patients with peri-implant mucositis was associated with increased risk for onset of peri-implantitis; (iv) whereas plaque accumulation has been established as aetiological factor, smoking was identified as modifiable patient-related and excess cement as local risk indicator for the development of peri-implant mucositis; (v) patient-administered mechanical plaque control (with manual or powered toothbrushes) has been shown to be an effective preventive measure; (vi) professional intervention comprising oral hygiene instructions and mechanical debridement revealed a reduction in clinical signs of inflammation; (vii) adjunctive measures (antiseptics, local and systemic antibiotics, air-abrasive devices) were not found to improve the efficacy of professionally administered plaque removal in reducing clinical signs of inflammation. CONCLUSIONS: Consensus was reached on recommendations for patients with dental implants and oral health care professionals with regard to the efficacy of measures to manage peri-implant mucositis. It was particularly emphasized that implant placement and prosthetic reconstructions need to allow proper personal cleaning, diagnosis by probing and professional plaque removal. [less ▲]Detailed reference viewed: 13 (1 ULg) Near-Death Experiences in patients with locked-in syndrome: Not always a blissful journeyCharland-Verville, Vanessa ; Lugo, Zulay; Jourdan, Jean-Pierre et alin Consciousness & Cognition (2015), 34Memories of Near-Death Experiences (NDEs) most often are recounted as emotionally positive events. At present, no satisfactory explanatory model exists to fully account for the rich phenomenology of NDEs ... [more ▼]Memories of Near-Death Experiences (NDEs) most often are recounted as emotionally positive events. At present, no satisfactory explanatory model exists to fully account for the rich phenomenology of NDEs following a severe acute brain injury. The particular population of patients with locked-in syndrome (LIS) provides a unique opportunity to study NDEs following infratentorial brain lesions. We here retrospectively characterized the content of NDEs in 8 patients with LIS caused by an acute brainstem lesion (i.e., ‘‘LIS NDEs’’) and 23 NDE experiencers after coma with supratentorial lesions (i.e., ‘‘classical NDEs’’). Compared to ‘‘classical NDEs’’, ‘‘LIS NDEs’’ less frequently experienced a feeling of peacefulness or well-being. It could be hypothesized that NDEs containing less positive emotions might have a specific neuroanatomical substrate related to impaired pontine/paralimbic connectivity or alternatively might be related to the emotional distress caused by the presence of conscious awareness in a paralyzed body. [less ▲]Detailed reference viewed: 95 (19 ULg) Biomarkers and physiolpathology in the cardiorenal syndromeBOUQUEGNEAU, Antoine ; KRZESINSKI, Jean-Marie ; DELANAYE, Pierre et alin Clinica Chimica Acta (2015), 443Acute cardiorenal syndrome (CRS) corresponds to an association of acute heart failure and a worsening of renal function. The detection of acute kidney injury (AKI) unfortunately occurs at a late stage of ... [more ▼]Acute cardiorenal syndrome (CRS) corresponds to an association of acute heart failure and a worsening of renal function. The detection of acute kidney injury (AKI) unfortunately occurs at a late stage of CRS, leading to an increased mortality of the patients. In this review, we described the pathophysiology of CRS and discussed the potential interest of biochemical biomarkers (namely creatinine, cystatin C, NGAL, KIM-1, fatty acid binding protein, Nacetyl-β-D-glucosaminidase and IL-18) that could potentially help to detect AKI earlier and thus reduce the morbi-mortality of the patients suffering from CRS. [less ▲]Detailed reference viewed: 30 (8 ULg) Progress on research on rodents and rodent-borne zoonoses in Southeast AsiaBlasdell, Kim; Bordes, Frédéric; Chaisiri, Kittipong et alin Wildlife Research (2015), 42(2), 98-107This review aims to synthesize the knowledge on the taxonomy of Southeast Asian murine rodents and the challenges associated with the identification of habitat preferences and associated rodent-borne ... [more ▼]This review aims to synthesize the knowledge on the taxonomy of Southeast Asian murine rodents and the challenges associated with the identification of habitat preferences and associated rodent-borne diseases. Recent studies concerning the Rattini tribe have identified unclear species boundaries that would benefit from further investigation. The development of barcoding may allow more accurate identification of rodents, specifically for complex species. However, knowledge on the distribution and habitat specializations of many common murine rodents is still scarce, particularly regarding the specific habitat preferences of most synanthropic rodent species (Rattus tanezumi or Rattus exulans). Several studies have analyzed the prevalence of major rodent-borne diseases in Southeast Asia and it appears that the greatest risk of rodent zoonoses are in the lowland rainfed and irrigated landscapes, generally in and around rice fields. [less ▲]Detailed reference viewed: 59 (6 ULg) BRCA1 germline mutation and glioblastoma development: report of casesBoukerroucha, Meriem ; Josse, Claire ; SEGERS, Karin et alin BMC Cancer (2015), 15Background Germline mutations in breast cancer susceptibility gene 1 (BRCA1) increase the risk of breast and ovarian cancers. However, no association between BRCA1 germline mutation and glioblastoma ... [more ▼]Background Germline mutations in breast cancer susceptibility gene 1 (BRCA1) increase the risk of breast and ovarian cancers. However, no association between BRCA1 germline mutation and glioblastoma malignancy has ever been highlighted. Here we report two cases of BRCA1 mutated patients who developed a glioblastoma (GBM). Cases presentation Two patients diagnosed with triple negative breast cancer (TNBC) were screened for BRCA1 germline mutation. They both carried a pathogenic mutation introducing a premature STOP codon in the exon 11 of the BRCA1 gene. Few years later, both patients developed a glioblastoma and a second breast cancer. In an attempt to clarify the role played by a mutated BRCA1 allele in the GBM development, we investigated the BRCA1 mRNA and protein expression in breast and glioblastoma tumours for both patients. The promoter methylation status of this gene was also tested by methylation specific PCR as BRCA1 expression is also known to be lost by this mechanism in some sporadic breast cancers. Conclusion Our data show that BRCA1 expression is maintained in glioblastoma at the protein and the mRNA levels, suggesting that loss of heterozygosity (LOH) did not occur in these cases. The protein expression is tenfold higher in the glioblastoma of patient 1 than in her first breast carcinoma, and twice higher in patient 2. In agreement with the high protein expression level in the GBM, BRCA1 promoter methylation was not observed in these tumours. In these two cases, despite of a BRCA1 pathogenic germline mutation, the tumour-suppressor protein expression is maintained in GBM, suggesting that the BRCA1 mutation is not instrumental for the GBM development. [less ▲]Detailed reference viewed: 29 (2 ULg) Gigantism, acromegaly, and GPR101 mutations.Daly, Adrian ; Trivellin, Giampaolo; Stratakis, Constantinein New England Journal of Medicine (2015), 372(13), 1265Detailed reference viewed: 16 (4 ULg) Adherence to physical activity recommendations and its associated factors: an interregional population-based studyAlkerwi, Ala'a; Schuh, Barbara; Sauvageot, Nicolas et alin Journal of Public Health Research (2015), 4(1), Background. Though the influence of physical activity in preventing cardiovascular diseases is well documented, only a few comparative studies have determined the degree of adherence to physical activity ... [more ▼]Background. Though the influence of physical activity in preventing cardiovascular diseases is well documented, only a few comparative studies have determined the degree of adherence to physical activity recommendations among populations and identified the demographic, socioeconomic, behavioural and health-related factors associated with good compliance. Design and methods. Cross-sectional interregional NESCaV survey of 3133 subjects compared three populations, Luxembourg, Lorraine (France) and Wallonia (Belgium), by using the International Physical Activity Questionnaire. Age and gender prevalence rates of physical activity were standardized to the European population. Results. The likelihood to meet the recommendations was higher in Luxembourg, after adjustment for age, gender, education, employment, weight status, morbidity score, health perception and level of importance attributed to the practice of physical activity (P<0.0001). The odds for meeting the recommendations were significantly higher among those with secondary than tertiary education. Compared to good self-health perception, subjects with poor or fair self-perceived health were less likely to meet the recommendations; this also applied to those attributing little or enough importance to physical activity compared with great importance. Conclusions. Region, education, self-perceived health and perception of importance of physical activity were emerged as independent determinants of meeting the recommendations. Awareness of the positive health effects of physical activity might thus be crucial for motivating the people to become more active. Further research is needed to explore potential region-specific factors which might explain the difference in population behaviours with respect to physical activity. [less ▲]Detailed reference viewed: 10 (3 ULg) Ferromagnetism induced by entangled charge and orbital orderings in ferroelectric titanate perovskitesBristowe, Nicholas ; Varignon, Julien ; Fontaine, Denis et alin Nature Communications (2015), 6In magnetic materials, the Pauli exclusion principle typically drives anti-alignment between electron spins on neighbouring species resulting in antiferromagnetic behaviour. Ferromagnetism exhibiting ... [more ▼]In magnetic materials, the Pauli exclusion principle typically drives anti-alignment between electron spins on neighbouring species resulting in antiferromagnetic behaviour. Ferromagnetism exhibiting spontaneous spin alignment is a fairly rare behaviour, but once materialized is often associated with itinerant electrons in metals. Here we predict and rationalize robust ferromagnetism in an insulating oxide perovskite structure based on the popular titanate series. In half-doped layered titanates, the combination of Jahn–Teller and oxygen breathing motions opens a band gap and creates an unusual charge and orbital ordering of the Ti d electrons. It is argued that this intriguingly intricate electronic network favours the elusive inter-site ferromagnetic (FM) ordering, on the basis of intra-site Hund's rules. Finally, we find that the layered oxides are also ferroelectric with a spontaneous polarization approaching that of ​BaTiO3. The concepts are general and design principles of the technologically desirable FM ferroelectric multiferroics are presented. [less ▲]Detailed reference viewed: 63 (12 ULg) Using XCO2 retrievals for assessing the long-term consistency of NDACC/FTIR data setsBarthlott, S; Schneider, M; Hase, F et alin Atmospheric Measurement Techniques (2015), 8Within the NDACC (Network for the Detection of Atmospheric Composition Change), more than 20 FTIR (Fourier-transform infrared) spectrometers, spread worldwide, provide long-term data records of many ... [more ▼]Within the NDACC (Network for the Detection of Atmospheric Composition Change), more than 20 FTIR (Fourier-transform infrared) spectrometers, spread worldwide, provide long-term data records of many atmospheric trace gases. We present a method that uses measured and modelled XCO2 for assessing the consistency of these NDACC data records. Our XCO2 retrieval setup is kept simple so that it can easily be adopted for any NDACC/FTIR-like measurement made since the late 1950s. By a comparison to coincident TCCON (Total Carbon Column Observing Network) measurements, we empirically demonstrate the useful quality of this suggested NDACC XCO2 product (empirically obtained scatter between TCCON and NDACC is about 4‰ for daily mean as well as monthly mean comparisons, and the bias is 25 ‰). Our XCO2 model is a simple regression model fitted to CarbonTracker results and the Mauna Loa CO2 in situ records. A comparison to TCCON data suggests an uncertainty of the model for monthly mean data of below 3 ‰. We apply the method to the NDACC/FTIR spectra that are used within the project MUSICA (multi-platform remote sensing of isotopologues for investigating the cycle of atmospheric water) and demonstrate that there is a good consistency for these globally representative set of spectra measured since 1996: the scatter between the modelled and measured XCO2 on a yearly time scale is only 3 ‰. [less ▲]Detailed reference viewed: 59 (7 ULg) Age-dependent expression of osteochondrosis-related genes in equine leukocytesMendoza García, Luis ; Piquemal, David; Lejeune, Jean-Philippe et alin Veterinary Record : Journal of the British Veterinary Association (2015), 2Introduction: Osteochondrosis (OC) is a developmental disease in horses which has a significant impact on the horse’s welfare and performance. The early disturbance in the process of endochondral ... [more ▼]Introduction: Osteochondrosis (OC) is a developmental disease in horses which has a significant impact on the horse’s welfare and performance. The early disturbance in the process of endochondral ossification progresses to inflammatory and repair processes in older horses. Previously, differentially expressed genes in leukocytes of OC-affected horses have been identified. The aim of the present study is to detect age-related changes in these differentially expressed genes. Materials and Methods: The expression of OC-related genes was analysed by real-time PCR and subsequent statistical analysis (ΔΔCT) in the leukocytes of 135 Belgian Warmblood horses divided into three different age groups: 30 months (n=38). Results: Relative expression of genes of horses less than 12 months of age showed significant induction of the genes MGAT4A, PRKCG, MHCI, ApoB, ApoB3G, B4GALT6 and a significantly lower expression of the genes OAS3. Horses of 18–24 months of age, showed a significantly higher expression of the genes TBC1D9, MGAT4A, IFIH1, MHCIIa and MMP1. Horses of more than 30 months of age showed a significantly higher expression of the genes MGAT4A, HP, SECTM1 compared with their age-matched control groups. Conclusions: The study demonstrates that OC-related genes are differentially expressed in horses of different ages compared with their age-matched controls. Some of the genes may be implicated in cell signalling and differentiation as well as carbohydrate and lipid metabolism and inflammation. However, the causal relationship between the differentially expressed genes and the development and progression of the OC lesions needs to be determined. [less ▲]Detailed reference viewed: 12 (2 ULg) Benoît Berthou (dir.), La bande dessinée : quelle lecture, quelle culture ?Crucifix, Benoît in Lectures (2015)Detailed reference viewed: 15 (1 ULg) Comment optimiser l’efficience de l’aide internationale, dans le domaine de la santé, en République Démocratique du CongoManzambi Kuwekita, Joseph ; Bruyère, Olivier ; Guillaume, Michèle et alin Santé Publique : Revue Multidisciplinaire pour la Recherche et l'Action (2015), 27(Janvier-Févier), 129-134Analysis of national health insurance accounts in the Democratic Republic of Congo (DRC) clearly shows the importance of international sanitary aid, particularly for the funding of general referral ... [more ▼]Analysis of national health insurance accounts in the Democratic Republic of Congo (DRC) clearly shows the importance of international sanitary aid, particularly for the funding of general referral hospitals, the management of inpatients with AIDS, administration of health zones and funding of preventive care providers. It The targeted changes described in this article could possibly optimize the efficiency of international aid for the DRC population, mainly for disorders considered to be a health care priority (i.e. malaria, AIDS, tuberculosis) as well as in the fight against malnutrition. Recommendations target the implementation of procedures for control of food chain security, changes in lifestyle and dietary habits of the population but also comprise extensive restructuring of the health care administration. A dramatic change of the structure in charge of drug distribution as well as eradication of the transfer of part of public health structure income to public health administrative personnel could result in the allocation of significant funds to the fight against the most important diseases. Better collaboration between the various departments in charge of health care professional training, together with enhanced responsibility of health care personnel is essential. Independent and respected non-governmental organizations should be involved in an audit process, targeting all aspects of the current DRC health system. Eventually, in an equal opportunity perspective, taking into consideration the very high degree of poverty of DRC inhabitants, implementation of health insurance programmes, use of generic drugs and generalization of micro-credit initiatives should also be implemented. [less ▲]Detailed reference viewed: 56 (17 ULg) Century-scale simulations of the response of the West Antarctic Ice Sheet to a warming climateCornford, S.L.; Martin, D.F.; Payne, A.J. et alin Cryosphere Discussions (The) (2015), 9We use the BISICLES adaptive mesh ice sheet model to carry out one, two, and three century simulations of the fast-flowing ice streams of the West Antarctic Ice Sheet. Each of the simulations begins with ... [more ▼]We use the BISICLES adaptive mesh ice sheet model to carry out one, two, and three century simulations of the fast-flowing ice streams of the West Antarctic Ice Sheet. Each of the simulations begins with a geometry and velocity close to present day observations, and evolves according to variation in meteoric ice accumulation, ice shelf melting, and mesh resolution. Future changes in accumulation and melt rates range from no change, through anomalies computed by atmosphere and ocean models driven by the E1 and A1B emissions scenarios, to spatially uniform melt rates anomalies that remove most of the ice shelves over a few centuries. We find that variation in the resulting ice dynamics is dominated by the choice of initial conditions, ice shelf melt rate and mesh resolution, although ice accumulation affects the net change in volume above flotation to a similar degree. Given sufficient melt rates, we compute grounding line retreat over hundreds of kilometers in every major ice stream, but the ocean models do not predict such melt rates outside of the Amundsen Sea Embayment until after 2100. Sensitivity to mesh resolution is spurious, and we find that sub-kilometer resolution is needed along most regions of the grounding line to avoid systematic under-estimates of the retreat rate, although resolution requirements are more stringent in some regions – for example the Amundsen Sea Embayment – than others – such as the Möller and Institute ice streams. [less ▲]Detailed reference viewed: 19 (2 ULg) Imaging myeloma and related monoclonal plasma cell disorders using MRI, low dose whole-body CT and FDG PET/CTWITHOFS, Nadia ; NANNI, C.; SIMONI, Paolo et alin Clinical and Translational Imaging (2015)Detailed reference viewed: 18 (1 ULg) Siltation and Pollution of Rivers in the Western Highlands of Cameroon: a Consequence of Farmland Erosion and RunoffDjoukeng, Henri Grisseur ; Tankou, Christopher Mubeteneh; Degré, Aurore in International Journal of Agricultural Research and Reviews (2015), 3(3), 206-212In the Western Highlands agro-ecological zone of Cameroon, rivers are constantly silted and polluted with eroded sediment and waste from cultivated land. This study characterizes and quantifies the amount ... [more ▼]In the Western Highlands agro-ecological zone of Cameroon, rivers are constantly silted and polluted with eroded sediment and waste from cultivated land. This study characterizes and quantifies the amount of material coming from plots cultivated in the Méloh Watershed. In a natural rocky-bottomed well measuring 0.90 m deep, 3 m long, and 2.5 m wide, for a period of three years we performed the collection, differentiation, and measurement of trapped sediment in the cultivated part of river that runs through the watershed. Both cultivated sides of the watershed had fairly regular slopes of 14% on one side and 17% on the other side. The material retrieved consisted of soil, plant residues, chemical packages, and plastic casing used for irrigation. During the years 2012 and 2013, farmers practiced both flatbed cultivation and ridging along the steepest slopes. These two methods of land preparation are inefficient in terms of water conservation, as evidenced by the collection of 10.429 t.ha-1 average total sediment per year during this period. Tied ridging cultivation method was experimented during the 2013 crop year and adopted on 75% of plots in 2014. We subsequently collected 3.586 t.ha-1 total sediment, a decrease of 65.61% compared to the average of previous years. The tied ridging cultivation method significantly reduced siltation of the Méloh River (p<0.05). This study showed that traditional agricultural practices are a principal cause of siltation and pollution of the Méloh River. By extrapolation, we can state that the problem must occur in almost all rivers in the study area with similar topography and agricultural practices [less ▲]Detailed reference viewed: 46 (18 ULg) Greenland high-elevation mass balance: inference and implication of reference period (1961–90) imbalanceColgan, W.; Box, J.; Andersen, M. et alin Annals of Glaciology (2015), 56(70), 105117We revisit the input–output mass budget of the high-elevation region of the Greenland ice sheet evaluated by the Program for Arctic Regional Climate Assessment (PARCA). Our revised reference period ... [more ▼]We revisit the input–output mass budget of the high-elevation region of the Greenland ice sheet evaluated by the Program for Arctic Regional Climate Assessment (PARCA). Our revised reference period (1961–90) mass balance of 54 48 Gt a–1 is substantially greater than the 0 21 Gt a–1 assessed by PARCA, but consistent with a recent, fully independent, input–output estimate of high-elevation mass balance (41 61 Gt a–1). Together these estimates infer a reference period high-elevation specific mass balance of 4.8 5.4 cm w.e. a–1. The probability density function (PDF) associated with this combined input–output estimate infers an 81% likelihood of high-elevation specific mass balance being positive (>0 cm w.e. a–1) during the reference period, and a 70% likelihood that specific balance was >2 cm w.e. a–1. Given that reference period accumulation is characteristic of centurial and millennial means, and that in situ mass-balance observations exhibit a dependence on surface slope rather than surface mass balance, we suggest that millennial-scale ice dynamics are the primary driver of subtle reference period high-elevation mass gain. Failure to acknowledge subtle reference period dynamic mass gain can result in underestimating recent dynamic mass loss by 17%, and recent total Greenland mass loss by 7%. [less ▲]Detailed reference viewed: 79 (0 ULg) Optimization of a PGSS (particles from gas saturated solutions) process for a fenofibrate lipid-based solid dispersion formulationPestieau, Aude ; Krier, Fabrice ; Lebrun, Pierre et alin International Journal of Pharmaceutics (2015), 485The aim of this study was to develop a formulation containing fenofibrate and Gelucire® 50/13 (Gattefossé, France) in order to improve the oral bioavailability of the drug. Particles from Gas Saturated ... [more ▼]The aim of this study was to develop a formulation containing fenofibrate and Gelucire® 50/13 (Gattefossé, France) in order to improve the oral bioavailability of the drug. Particles from Gas Saturated Solutions (PGSS) process was chosen for investigation as a manufacturing process for producing a solid dispersion. The PGSS process was optimized according to the in vitro drug dissolution profile obtained using a biphasic dissolution test. Using a design of experiments approach, the effects of nine experimental parameters were investigated using a PGSS apparatus provided by Separex® (Champigneulles, France). Within the chosen experimental conditions, the screening results showed that the drug loading level, the autoclave temperature and pressure, the connection temperature and the nozzle diameter had a significant influence on the dissolution profile of fenofibrate. During the optimization step, the three most relevant parameters were optimized using a central composite design, while other factors remained fixed. In this way, we were able to identify the optimal production conditions that would deliver the highest level of fenofibrate in the organic phase at the end of the dissolution test. The closeness between the measured and the predicted optimal dissolution profiles in the organic phase demonstrated the validity of the statistical analyses. [less ▲]Detailed reference viewed: 26 (4 ULg) Associations of Wheat with Pea Can Reduce Aphid InfestationsChevalier Mendes Lopes, Thomas ; Bodson, Bernard ; Francis, Frédéric in Neotropical Entomology (2015)Increasing plant diversity within crops can be beneficial for pest control. In this field study, the effects of two wheat and pea associations (mixed cropping and strip cropping) on aphid populations were ... [more ▼]Increasing plant diversity within crops can be beneficial for pest control. In this field study, the effects of two wheat and pea associations (mixed cropping and strip cropping) on aphid populations were compared with pure stands of both crops by observations on tillers and plants. Pea was more susceptible to infestations than wheat. As expected, the density of aphid colonies was significantly higher in pure stands during the main occurrence periods, compared with associations. Additionally, flying beneficials, such as not only aphidophagous adult ladybirds but also parasitoid, hoverfly and lacewing species that feed on aphids at the larval stage, were monitored using yellow pan traps. At specific times of the sampling season, ladybirds and hoverflies were significantly more abundant in the pure stand of pea and wheat, respectively, compared with associations. Few parasitoids and lacewings were trapped. This study showed that increasing plant diversity within crops by associating cultivated species can reduce aphid infestations, since host plants are more difficult to locate. However, additional methods are needed to attract more efficiently adult beneficials into wheat and pea associations. [less ▲]Detailed reference viewed: 30 (7 ULg) Microwave-stimulated superconductivity due to presence of vorticesLara, Antonio; Aliev, Farkhad; Silhanek, Alejandro et alin Scientific Reports (2015), 5The response of superconducting devices to electromagnetic radiation is a core concept implemented in diverse applications, ranging from the currently used voltage standard to single photon detectors in ... [more ▼]The response of superconducting devices to electromagnetic radiation is a core concept implemented in diverse applications, ranging from the currently used voltage standard to single photon detectors in astronomy. Suprisingly, a sufficiently high power subgap radiation may stimulate superconductivity itself. The possibility of stimulating type II superconductors, in which the radiation may interact also with vortex cores, remains however unclear. Here we report on superconductivity enhanced by GHz radiation in type II superconducting Pb films in the presence of vortices. The stimulation effect is more clearly observed in the upper critical field and less pronounced in the critical temperature. The magnetic field dependence of the vortex related microwave losses in a film with periodic pinning reveals a reduced dissipation of mobile vortices in the stimulated regime due to a reduction of the core size. Results of numerical simulations support the validy of this conclusion. Our findings may have intriguing connections with holographic superconductors in which the possibility of stimulation is under current debate. [less ▲]Detailed reference viewed: 62 (3 ULg) Trends of ozone total columns and vertical distribution from FTIR observations at eight NDACC stations around the globeVigouroux, C; Blumenstock, T; Coffey, M et alin Atmospheric Chemistry and Physics (2015), 15Ground-based Fourier transform infrared (FTIR) measurements of solar absorption spectra can provide ozone total columns with a precision of 2 % but also independent partial column amounts in about four ... [more ▼]Ground-based Fourier transform infrared (FTIR) measurements of solar absorption spectra can provide ozone total columns with a precision of 2 % but also independent partial column amounts in about four vertical layers, one in the troposphere and three in the stratosphere up to about 45 km, with a precision of 5–6 %. We use eight of the Network for the Detection of Atmospheric Composition Change (NDACC) stations having a long-term time series of FTIR ozone measurements to study the total and vertical ozone trends and variability, namely, Ny-Ålesund (79ºN), Thule (77ºN), Kiruna (68ºN), Harestua (60ºN), Jungfraujoch (47ºN), Izaña (28ºN), Wollongong (34ºS) and Lauder (45ºS). The length of the FTIR time series varies by station but is typically from about 1995 to present. We applied to the monthly means of the ozone total and four partial columns a stepwise multiple regression model including the following proxies: solar cycle, quasi-biennial oscillation (QBO), El Niño–Southern Oscillation (ENSO), Arctic and Antarctic Oscillation (AO/AAO), tropopause pressure (TP), equivalent latitude (EL), Eliassen–Palm flux (EPF), and volume of polar stratospheric clouds (VPSC). At the Arctic stations, the trends are found mostly negative in the troposphere and lower stratosphere, very mixed in the middle stratosphere, positive in the upper stratosphere due to a large increase in the 1995–2003 period, and non-significant when considering the total columns. The trends for mid-latitude and subtropical stations are all non-significant, except at Lauder in the troposphere and upper stratosphere and at Wollongong for the total columns and the lower and middle stratospheric columns where they are found positive. At Jungfraujoch, the upper stratospheric trend is close to significance (+0.9 ± 1.0 %/decade). Therefore, some signs of the onset of ozone mid-latitude recovery are observed only in the Southern Hemisphere, while a few more years seem to be needed to observe it at the northern mid-latitude station. [less ▲]Detailed reference viewed: 32 (4 ULg) Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitorsVillarejo, Ana; Molina Ortiz, Patricia ; Montenegro, Yenny et alin Carcinogenesis (2015), 36(5), 585-597Snail2 is a zinc finger transcription factor involved in driving epithelial to mesenchymal transitions. Snail2 null mice are viable, but display defects in melanogenesis, gametogenesis and hematopoiesis ... [more ▼]Snail2 is a zinc finger transcription factor involved in driving epithelial to mesenchymal transitions. Snail2 null mice are viable, but display defects in melanogenesis, gametogenesis and hematopoiesis, and are markedly radiosensitive. Here, using mouse genetics, we have studied the contributions of Snail2 to epidermal homeostasis and skin carcinogenesis. Snail2 −/− mice presented a defective epidermal terminal differentiation and, unexpectedly, an increase in number, size and malignancy of tumor lesions when subjected to the two-stage mouse skin chemical carcinogenesis protocol, compared with controls. Additionally, tumor lesions from Snail2 −/− mice presented a high inflammatory component with an elevated percentage of myeloid precursors in tumor lesions that was further increased in the presence of the anti-inflammatory agent dexamethasone. In vitro studies in Snail2 null keratinocytes showed that loss of Snail2 leads to a decrease in proliferation indicating a non-cell autonomous role for Snail2 in the skin carcinogenic response observed in vivo. Bone marrow (BM) cross-reconstitution assays between Snail2 wild-type and null mice showed that Snail2 absence in the hematopoietic system fully reproduces the tumor behavior of the Snail2 null mice and triggers the accumulation of myeloid precursors in the BM, blood and tumor lesions. These results indicate a new role for Snail2 in preventing myeloid precursors recruitment impairing skin chemical carcinogenesis progression. [less ▲]Detailed reference viewed: 14 (1 ULg) Efficacy of a web-based, center-based or combined physical activity intervention among older adultsMouton, Alexandre ; Cloes, Marc in Health Education Research (2015)With more social support and environment-centered interventions being recommended in web-based interventions, this study examined the efficacy of three intervention conditions aimed at promoting physical ... [more ▼]With more social support and environment-centered interventions being recommended in web-based interventions, this study examined the efficacy of three intervention conditions aimed at promoting physical activity (PA) in older adults. The efficacy analyses included the self-reported PA level, stage of change for PA and awareness about PA among participants. Eligible participants (N = 149; M = 65 years old, SD = 6), recruited in a unique Belgian French-speaking municipality, were randomized in four research arms for a 3-month intervention: (i) web-based; (ii) center-based; (iii) mixed (combination of web- and center-based); and (iv) control (no intervention). Web-based condition included a PA website and monthly tailored emails whereas center-based condition comprised 12 sessions (1 per week) of group exercising. With a significant increase in PA, the PA stage of change and the PA awareness at 12 months, the mixed intervention condition seemed to include the key social and motivating elements for sustainable behavior change. Center-based intervention was more likely to produce significant improvements of the PA level and the stage of change for PA change whereas web-based intervention was more likely to extend the awareness about PA. [less ▲]Detailed reference viewed: 20 (5 ULg) Bioassessment of trace element contamination of Mediterranean coastal waters using the seagrass Posidonia oceanicaRichir, Jonathan ; Salivas-Decaux, Maÿlis; Lafabrie, Céline et alin Journal of Environmental Management (2015), 150A large scale survey of the trace element (TE) contamination of Mediterranean coastal waters was performed from the analysis of Ag, As, Cd, Cu, Hg, Ni and Pb in the bioindicator Posidonia oceanica ... [more ▼]A large scale survey of the trace element (TE) contamination of Mediterranean coastal waters was performed from the analysis of Ag, As, Cd, Cu, Hg, Ni and Pb in the bioindicator Posidonia oceanica, sampled at 110 sites differing by their levels of exposure to contaminants. The holistic approach developed in this study, based on the combined utilization of several complementary monitoring tools, i.e. water quality scale, pollution index and spatial analysis, accurately assessed the TE contamination rate of Mediterranean coastal waters. In particular, the mapping of the TE contamination according to a new proposed 5-level water quality scale precisely outlined the contamination severity along Mediterranean coasts and facilitated interregional comparisons. Finally, the reliability of the use of P. oceanica as bioindicator species was again demonstrated through several global, regional and local detailed case studies. NB: The designations employed and the presentation of the information in thisdocument do not imply the expression of any opinion whatsoever on the part of the authors concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. [less ▲]Detailed reference viewed: 121 (30 ULg) Double thermo-responsive hydrogels from poly(vinylcaprolactam) containing diblock and triblock copolymersThomassin, Jean-Michel ; Mathieu, Kevin ; Kermagoret, Anthony et alin Polymer Chemistry (2015), 6(10), 1856-1864The thermally-induced gelation and gel properties of concentrated aqueous solutions of double thermoresponsive poly(N-vinylamide)-based di- and triblock copolymers are studied by rheology. The copolymers ... [more ▼]The thermally-induced gelation and gel properties of concentrated aqueous solutions of double thermoresponsive poly(N-vinylamide)-based di- and triblock copolymers are studied by rheology. The copolymers under investigation, prepared by cobalt-mediated radical polymerization and coupling reactions, are composed of poly(vinylcaprolactam) (PNVCL) blocks and of a statistical poly(vinylcaprolactam-stat-vinylpyrrolidone) segment with a cloud point temperature (TCP) higher than that of PNVCL. Heating the di- and triblock solutions beyond the first phase transition temperature favors gel formation while heating above the second TCP leads to opaque gels without macroscopic demixing. Moduli of the triblock hydrogels are systematically higher than those of the corresponding diblocks, even above the second transition. Rheological data suggest distinct micellar structures for each copolymer architecture: densely packed micelles of diblocks and 3-D networks of bridged micelles for triblocks. Strain sweep experiments also emphasize the positive effect of the micelle bridging on the elasticity and stability of the hydrogels. The formation and properties of the obtained gels are also shown to depend on the copolymer concentration, block length, and composition. Addition of salt also allows us to tune the phase transition temperatures of these double thermoresponsive hydrogels. [less ▲]Detailed reference viewed: 53 (11 ULg) Prognostic value of (18)F-FDG PET/CT in liver transplantation for hepatocarcinoma.Detry, Olivier ; Govaerts, Laurence; De Roover, Arnaud et alin World journal of gastroenterology : WJG (2015), 21(10), 3049-54AIM: To evaluate the prognostic value of pretreatment FDG positron emission tomography computed tomography (PET-CT) in patients with hepatocarcinoma treated by liver transplantation (LT). METHODS: The ... [more ▼]AIM: To evaluate the prognostic value of pretreatment FDG positron emission tomography computed tomography (PET-CT) in patients with hepatocarcinoma treated by liver transplantation (LT). METHODS: The authors retrospectively analyzed the data of 27 patients (mean age 58 +/- 9 years) who underwent FDG PET-CT before LT for hepatocarcinoma. Mean follow-up was 26 +/- 18 mo. The FDG PET/CT was performed according to a standard clinical protocol: 4 MBqFDG/kg body weight, uptake 60 min, low-dose non-enhanced CT. The authors measured the SUVmax and SUVmean of the tumor and the normal liver. The tumor/liver activity ratios (RSUVmax and RSUVmean) were tested as prognostic factors and compared to the following conventional prognostic factors: MILAN, CLIP, OKUDA, TNM stage, alphafoetoprotein level, portal thrombosis, size of the largest nodule, tumor differentiation, microvascular invasion, underlying cirrhosis and liver function. RESULTS: Overall and recurrence free survivals were 80.7% and 67.4% at 3 years, and 70.6% and 67.4% at 5 years, respectively. According to a multivariate Cox model, only FDG PET/CT RSUVmax predicted recurrence free survival. Even though the MILAN criteria alone were not predictive, it is worth noting that none of the patients outside the MILAN criteria and with RSUVmax < 1.15 relapsed. CONCLUSION: FDG PET/CT with an RSUVmax cut-off value of 1.15 is a strong prognostic factor for recurrence and death in patients with HCC treated by LT in this retrospective series. Further prospective studies should test whether this metabolic index should be systematically included in the preoperative assessment. [less ▲]Detailed reference viewed: 44 (7 ULg) Artificial Intelligence in Video Games: Towards a Unified FrameworkSafadi, Firas ; Fonteneau, Raphaël ; Ernst, Damien in International Journal of Computer Games Technology (2015), 2015With modern video games frequently featuring sophisticated and realistic environments, the need for smart and comprehensive agents that understand the various aspects of complex environments is pressing ... [more ▼]With modern video games frequently featuring sophisticated and realistic environments, the need for smart and comprehensive agents that understand the various aspects of complex environments is pressing. Since video game AI is often specifically designed for each game, video game AI tools currently focus on allowing video game developers to quickly and efficiently create specific AI. One issue with this approach is that it does not efficiently exploit the numerous similarities that exist between video games not only of the same genre, but of different genres too, resulting in a difficulty to handle the many aspects of a complex environment independently for each video game. Inspired by the human ability to detect analogies between games and apply similar behavior on a conceptual level, this paper suggests an approach based on the use of a unified conceptual framework to enable the development of conceptual AI which relies on conceptual views and actions to define basic yet reasonable and robust behavior. The approach is illustrated using two video games, Raven and StarCraft: Brood War. [less ▲]Detailed reference viewed: 414 (36 ULg) Mutant p53 promotes tumor cell malignancy by both positive and negative regulation of TGF-β pathwayLei Ji; Jinjin Xu; Jian Liu et alin Journal of Biological Chemistry (2015)Specific p53 mutations abrogate the tumor suppressive functions by gaining new abilities to promote tumorigenesis. Inactivation of p53 is known to distort the TGF-β signaling, which paradoxically displays ... [more ▼]Specific p53 mutations abrogate the tumor suppressive functions by gaining new abilities to promote tumorigenesis. Inactivation of p53 is known to distort the TGF-β signaling, which paradoxically displays both tumor-suppressive and pro-oncogenic function. The molecular mechanisms how mutant p53 simultaneously antagonizes tumor-suppressive and synergizes tumor-promoting function of TGF-β pathway remain elusive. Here we demonstrate that mutant p53 differentially regulates subsets of TGF-β target genes, by an enhanced binding to the MH2 domain in Smad3 upon the integration of ERK signaling, therefore disrupting the Smad3/Smad4 complex formation. Silencing Smad2, inhibition of ERK or introducing a phosphorylation defective mutation at Ser392 in p53 abrogates the R175H mutant p53 dependent regulation of these TGF- β target genes. Our study provide a mechanism to reconcile the seemingly contradictory observations that mutant p53 can both attenuate and cooperate with the TGF-β pathway to promote cancer cell malignancy in a same cell type. [less ▲]Detailed reference viewed: 19 (2 ULg) Phase Transformations and Crack Initiation in a High-Chromium Cast Steel Under Hot Compression TestsTchuindjang, Jérôme Tchoufack ; Neira Torres, Ingrid; Fores, Paulo et alin Journal of Materials Engineering and Performance (2015), 24(5), 2025-2041The mechanical behavior of the fully austenitic matrix of high-chromium cast steel (HCCS) alloy is determined by external compression stress applied at 300 and 700 C. The microstructure is roughly ... [more ▼]The mechanical behavior of the fully austenitic matrix of high-chromium cast steel (HCCS) alloy is determined by external compression stress applied at 300 and 700 C. The microstructure is roughly characterized toward both optical and scanning electron microscopy analyses. Dilatometry is used during heating from room temperature up to austenitization to study the solid-state phase transformations, precipitation, and dissolution reactions. Two various strengthening phenomena (precipitation hardening and stress-induced bainite transformation) and one softening mechanism (dynamic recovery) are highlighted from compression tests. The influence of the temperature and the carbide type on the mechanical behavior of the HCCS material is also enhanced. Cracks observed on grain boundary primary carbides allow establishing a rough damage model. The crack initiation within the HCCS alloy is strongly dependent on the temperature, the externally applied stress, and the matrix strength and composition. [less ▲]Detailed reference viewed: 33 (16 ULg) KLF17 empowers TGF-β/Smad signaling by targeting Smad3-dependent pathway to suppress tumor growth and metastasis during cancer progression.Ali, Amjad ; Zhang P; Liangfang Y et alin cell death and disease (2015)Inhibition of tumor suppressive signaling is linked to cancer progression, metastasis and epithelial-mesenchymal transition (EMT). Transforming growth factor-β1 (TGF-β)/Smad signaling plays an important ... [more ▼]Inhibition of tumor suppressive signaling is linked to cancer progression, metastasis and epithelial-mesenchymal transition (EMT). Transforming growth factor-β1 (TGF-β)/Smad signaling plays an important role in tumor suppression. Kruppel-like-factor 17 (KLF17) is a negative regulator of metastasis and EMT. However, underlying mechanisms leading to tumor suppressive and anti-metastatic function of KLF17 still remains unknown. Here, we show that KLF17 plays an integral role in potentiating TGF-β/Smad signaling via Smad3-dependent pathway to suppress tumor progression. Intriguingly, TGF-β/Smad3 signaling induces KLF17 expression, generating a positive feedback loop. TGF-β/Smad3-KLF17 loop is critical for anti-metastasis and tumor inhibition in cancer cells. Mechanistically, silencing KLF17 reduced Smad3-DNA complex formation on Smad binding element (SBE) and affects the expression of TGF-β/Smad target genes. Moreover, KLF17 alters Smad3 binding pattern on chromatin. KLF17 regulates TGF-β target genes that are Smad3-dependent. Smad3 and KLF17 physically interact with each other via KLF17 responsive elements/SBE region. Intriguingly, TGF-β stimulates the recruitment of KLF17 on chromatin to subsets of metastasis-associated genes. Functionally, depletion of KLF17 enhanced tumorigenic features in cancer cells. KLF17 is critical for full cytostatic function of TGF-β/Smad signaling. Clinically, KLF17 expression significantly decreases during advance HCC. KLF17 shows positive correlation with Smad3 levels in cancer samples. Our data shows that enhance KLF17 activity has important therapeutic implications for targeted-therapies aimed at TGF-β/Smad3 pathway. These findings define novel mechanism by which TGF-β/Smad-KLF17 pathway mutually affect each other during cancer metastasis, provide a new model of regulation of TGF-β/Smad signaling by KLF17 and defines new insights into anti-metastatic function of KLF17. [less ▲]Detailed reference viewed: 13 (1 ULg) The Role of Government in Path- Dependent Development of SME Sector in UkraineShutyak, Yuliya; Van Caillie, Didier in Journal of East-West Business (2015), 21(1), 67-90This article studies evolution of governmental support for SME development from the times of Perestroika until 2013. Guided by institutional theory, the article revises SME development in Ukraine and ... [more ▼]This article studies evolution of governmental support for SME development from the times of Perestroika until 2013. Guided by institutional theory, the article revises SME development in Ukraine and explains government actions through the prism of path dependence. The analysis is conducted within a matrix logic resuming the data by several periods of time corresponding to changes in the Ukrainian government and being juxtaposed to the main stages of the path dependence analytical framework. The study reveals main trends in governmental support for small business and main challenges remaining nowadays. [less ▲]Detailed reference viewed: 31 (1 ULg) Elastic and inelastic transmission in guided atom lasers: A truncated Wigner approachDujardin, Julien ; Argüelles, Arturo; Schlagheck, Peter in Physical Review A (2015), 91We study the transport properties of a Bose-Einstein condensate formed by an ultracold gas of bosonic atoms that is coupled from a magnetic trap into a one-dimensional waveguide. Our theoretical approach ... [more ▼]We study the transport properties of a Bose-Einstein condensate formed by an ultracold gas of bosonic atoms that is coupled from a magnetic trap into a one-dimensional waveguide. Our theoretical approach to tackling this problem is based on the truncated Wigner method for which we assume the system to consist of two semi-infinite noninteracting leads and a finite interacting scattering region with two constrictions modeling an atomic quantum dot. The transmission is computed in the steady-state regime and we find a good agreement between truncated Wigner and matrix-product state calculations. We also identify clear signatures of inelastic resonant scattering by analyzing the distribution of energy in the transmitted atomic-matter wave beam. [less ▲]Detailed reference viewed: 39 (3 ULg) An analysis of potential resistance of the phytophagous mite, Tetranychus urticae Koch (Acari: Tetranychidae) to four botanical pesticidesAttia, Sabrine; Lebdi, KL; Heuskin, Stéphanie et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2015), 19(3), 232-238Description of the subject. Synthetic acaricides have been widely used to manage Tetranychus urticae. Due to the excessive use of biocide and the associated problems of pesticide resistance and ... [more ▼]Description of the subject. Synthetic acaricides have been widely used to manage Tetranychus urticae. Due to the excessive use of biocide and the associated problems of pesticide resistance and environmental pollution, there is an increasing demand for sustainable, environmentally-friendly control methods. Among the current alternative strategies aimed at decreasing the pest populations, the pesticides based on plant extracts are currently one of the most promising methods. Essential oils with acaricidal properties have been categorized as green pesticides because they are biodegradable and predominantly non-toxic to vertebrates. Objectives. With an aim to reduce the use of synthetic pesticides, they represent a promising approach for eco-chemical control of mites. Method. The aim of the present work was to analyze the risk of resistance emergence of T. urticae to repeated treatments with four plant extracts: Deverra scoparia Coss. & Durieu (Araliales: Apiaceae), Hertia cheirifolia (L.) Kuntze (Asterales: Ateraceae), Santolina africana Jord. & Fourr. (Asterales: Asteraceae) essential oils and garlic distillate Allium sativum L. (Asparagales: Alliaceae) after 20 generations. Results. Repeated treatments with S. africana essential oil during 20 generations did not provoke an emergence of resistance while a low development of resistance was observed with H. cheirifolia, A. sativum and D. scoparia extracts. Conclusions. The efficacy of these extracts against the two spotted spider mite and their low development of resistance make them a promising use for pest management. [less ▲]Detailed reference viewed: 30 (4 ULg) Baryon resonances in large Nc QCDMatagne, Nicolas; Stancu, Floarea in Reviews of Modern Physics (2015), 87We review the current status and present open challenges of largeN_c$QCD baryon spectroscopy. After introducing the$1/N_c$expansion method we first shortly revisit the latest achievements for the ... [more ▼]We review the current status and present open challenges of large$N_c$QCD baryon spectroscopy. After introducing the$1/N_c$expansion method we first shortly revisit the latest achievements for the ground state properties. Next we discuss the applicability of this method to excited states, presenting two different approaches with their advantages and disadvantages. Selected results for the spectrum and strong and electromagnetic decays are described. We also present further developments for the applicability of the method to excited states, based on the qualitative compatibility between the quark excitation picture and the meson-nucleon scattering picture. We show that a quantitative comparison between results obtained from the mass formula of the$1/N_c$expansion method and quark models brings convincing support to quark models and shortly discuss the implications of different large$N_c$limits. We stress that the SU(6) spin-flavor structure of large$N_c\$ baryon allows a convenient classification of highly excited resonances into SU(3) multiplets and predicts mass ranges for the missing partners. [less ▲]Detailed reference viewed: 12 (1 ULg) Microbiological quality of surface water treated with Moringa oleifera seeds or cakes during the storage : case study of water reservoirs of Loumbila, Ziga and Ouaga 3 Dams in Burkina Faso.Kabore, Aminata; Savadogo, Boubacar; Otoidobiga, Harmonie C. et alin Journal of Water Resource and Protection (2015), 7Water purification with Moringa oleifera seeds has received a lot of attention because it reduces water turbidity and pathogenic microorganisms. However, it is important to define the optimum conditions ... [more ▼]Water purification with Moringa oleifera seeds has received a lot of attention because it reduces water turbidity and pathogenic microorganisms. However, it is important to define the optimum conditions of storage to preserve the treated water quality. The study aims to investigate microbial quality of water treated with Moringa oleifera seeds or cake coagulants inrelation to the storage temperature and shelf life in order to define the optimum conditions of storage. A total of 45 water samples from 3 water reservoirs of Loumbila, Ziga and Ouaga 3 dams were collected in sterile glass bottles and treated in triplicate with Moringa oleifera seeds or defatted cakes coagulants. Treated water samples obtained at optimum conditions were stored at room temperature (25°C - 30°C) and at 4°C. Fecal bacteria pollution indicators (Escherichia coli, fecal coliforms and fecal streptococcus) and parasites were monitored every 24 hours during three (3) days abased on laboratory standard methods. Data were analyzed using the Student's t-test and XLSTAT 7.5.2 statiscal software. From the results obtained, bacterial indicators increased significantly with storage temperature (p < 0.0001) and shelf life (p < 0.0001). However, for all water samples bacterial growth was more important in samples treated with Moringa oleifera cakes than seeds (p < 0.0001). For water samples treated with Moringa oleifera seeds and stored at room temperature, bacterial increase after 72 hours was 57 - 80, 42 - 50 and 22 - 47 CFU/100 ml for fecal coliforms, E. coli and fecal streptococcus, respectively. With Moringa oleifera cake's treatment, the increase was 63 - 104, 57 - 82 and 28 - 52 for the same indicators, respectively. Bacterial growth was also more important at room temperature than at 4°C. Thus, microbiological quality of water treated with Moringa oleifera seeds was better than cakes whatever storage temperature and shelf life. Overall, water treated with Moringa oleifera seeds should be stored at low temperature and consumed within 24 hours. [less ▲]Detailed reference viewed: 20 (5 ULg) Systematic classification of two-loop realizations of the Weinberg operatorAristizabal Sierra, Diego ; Hirsch, Martin; Degée, Audrey et alin Journal of High Energy Physics [=JHEP] (2015), 2015(03), We systematically analyze the d=5 Weinberg operator at 2-loop order. Using a diagrammatic approach, we identify two different interesting categories of neutrino mass models: (i) Genuine 2- loop models for ... [more ▼]We systematically analyze the d=5 Weinberg operator at 2-loop order. Using a diagrammatic approach, we identify two different interesting categories of neutrino mass models: (i) Genuine 2- loop models for which both, tree-level and 1-loop contributions, are guaranteed to be absent. And (ii) finite 2-loop diagrams, which correspond to the 1-loop generation of some particular vertex appearing in a given 1-loop neutrino mass model, thus being effectively 2-loop. From the large list of all possible 2-loop diagrams, the vast majority are infinite corrections to lower order neutrino mass models and only a moderately small number of diagrams fall into these two interesting classes. Moreover, all diagrams in class (i) are just variations of three basic diagrams, with examples discussed in the literature before. Similarly, we also show that class (ii) diagrams consists of only variations of these three plus two more basic diagrams. Finally, we show how our results can be consistently and readily used in order to construct two-loop neutrino mass models. [less ▲]Detailed reference viewed: 24 (2 ULg) Pre-employement examination for low back risk in workers exposesd to manual handling of loads : French guidelinesPETIT, Audrey; ROUSSEAU, Sandrine; HUEZ, Jean-François et alin International Archives of Occupational and Environmental Health (2015)Detailed reference viewed: 26 (1 ULg) How do harpacticoid copepods colonize detrital seagrass leaves?Mascart, Thibaud ; Agusto, Laura; Lepoint, Gilles et alin Marine Biology (2015), 162(5), 929-943An experiment was carried out investigating the colonization ability and specific pattern of copepods towards a provisional benthic habitat. Since copepods are known to disperse passively and actively ... [more ▼]An experiment was carried out investigating the colonization ability and specific pattern of copepods towards a provisional benthic habitat. Since copepods are known to disperse passively and actively, the experiment aimed to investigate the pool of colonizers of macrophytodetritus and the species-specific active colonization pathways. The experiment was performed in a Mediterranean seagrass Posidonia oceanica meadow on defaunated macrophytodetritus accumulations (mainly dead seagrass leaves) for two time intervals (24 h and 96 h). Active colonization by copepods, independently of their adjacent potential source pool habitat (bare sandy sediments, P. oceanica canopy, water column and macrophytodetritus) occurred within 24 h. Natural densities (as in the control treatments) were only reached by active colonization through the water column. Both neither diversities nor species composition of natural macrophytodetritus were ever reached by one single migratory pathway, therefore only a combination of interstitial migration and water column migration can explain the species occurrence under natural condition. Moreover, every potential adjacent source pool habitat, contributed species to the newly colonized macrophytodetritus. However, the main colonizers were mostly species with good swimming capabilities. The diverse pool of species present in the newly colonized macrophytodetritus underlines the complex communities and dispersion capabilities of copepods. Hence, macrophytodetritus possesses the potential ability to be a colonizer source pool for every adjacent habitat and thus behaves as a copepod hub for the entire seagrass ecosystem. [less ▲]Detailed reference viewed: 32 (7 ULg) Influence of the textural parameters of resorcinol–formaldehyde dry polymers and carbon xerogels on particle sizes upon mechanical millingPiedboeuf, Marie-Laure ; Léonard, Alexandre ; Traina, Karl et alin Colloids and Surfaces A : Physicochemical and Engineering Aspects (2015), 471Porous carbons find various applications in catalysis, electrochemical storage or sorption. Prior to use, their particle sizes need however to be controlled according to the targeted application. In this ... [more ▼]Porous carbons find various applications in catalysis, electrochemical storage or sorption. Prior to use, their particle sizes need however to be controlled according to the targeted application. In this study, the grinding behavior of materials prepared from aqueous resorcinol–formaldehyde mixtures and displaying different pore textures was studied in detail. Both dry polymer gels and pyrolyzed carbon xerogels were compared in terms of particle size distributions after planetary ball-milling. The results show that the pore texture and the qualitative hardness of the materials have a strong influence on the grinding behavior, especially if carbon xerogels pyrolyzed before grinding are considered. On the other hand, it appears that the milling of polymer gels, followed by a pyrolysis step, is the most efficient way to obtain homogeneous particle size distributions, for all of the investigated mesopore textures. In this case, carbon particles displaying a narrow grain size distribution centered on a mode value near 10 μm are successfully obtained after similar grinding durations, with retention of the mesopore texture of the starting materials. This work also demonstrates the possibility of using mercury intrusion porosimetry as an interesting tool to assess simultaneously the mesopore dimensions and the particle sizes of porous powders. [less ▲]Detailed reference viewed: 30 (1 ULg) Les droits fondamentaux, une substance malléable pour le juge? Propos sur la "dématérialisation" des droits fondamentauxRosoux, Géraldine in Justice-en-ligne (2015)Ce texte contient un résumé de la thèse de doctorat de l'auteur; il est disponible en ligne: http://www.justice-enligne.be/article706.html.Detailed reference viewed: 31 (4 ULg) Assessing the operation rules of a reservoir system based on a detailed modelling chainBruwier, Martin ; Erpicum, Sébastien ; Pirotton, Michel et alin Natural Hazards & Earth System Sciences (2015), 15The current operation rules of two muti-purpose reservoirs are analysed based on an integrated model including a hydrological model, a hydraulic model, a model of the reservoir system and a flood damage ... [more ▼]The current operation rules of two muti-purpose reservoirs are analysed based on an integrated model including a hydrological model, a hydraulic model, a model of the reservoir system and a flood damage model. Five performance indicators have been defined, reflecting the ability to provide drinking water, to control floods, to produce hydropower and to reduce low-flow conditions. Then, impacts of two climate change scenarios are assessed and enhanced operation rules are proposed for mitigation. [less ▲]Detailed reference viewed: 65 (27 ULg) The small binary asteroid (939) IsbergaCarry, B.; Matter, A.; Scheirich, P. et alin Icarus (2015), 248In understanding the composition and internal structure of asteroids, their density is perhaps the most diagnostic quantity. We aim here at characterizing the surface composition, mutual orbit, size, mass ... [more ▼]In understanding the composition and internal structure of asteroids, their density is perhaps the most diagnostic quantity. We aim here at characterizing the surface composition, mutual orbit, size, mass, and density of the small main-belt binary asteroid (939) Isberga. For that, we conduct a suite of multi-technique observations, including optical lightcurves over many epochs, near-infrared spectroscopy, and interferometry in the thermal infrared. We develop a simple geometric model of binary systems to analyze the interferometric data in combination with the results of the lightcurve modeling. From spectroscopy, we classify Ibserga as a Sq-type asteroid, consistent with the albedo of 0.14-0.06+0.09 (all uncertainties are reported as 3-σ range) we determine (average albedo of S-types is 0.197 ± 0.153, see Pravec et al. (Pravec et al. [2012]. Icarus 221, 365-387). Lightcurve analysis reveals that the mutual orbit has a period of 26.6304 ± 0.0001 h, is close to circular (eccentricity lower than 0.1), and has pole coordinates within 7° of (225°, +86°) in Ecliptic J2000, implying a low obliquity of 1.5-1.5+6.0 deg . The combined analysis of lightcurves and interferometric data allows us to determine the dimension of the system and we find volume-equivalent diameters of 12.4-1.2+2.5 km and 3.6-0.3+0.7 km for Isberga and its satellite, circling each other on a 33 km wide orbit. Their density is assumed equal and found to be 2.91-2.01+1.72 gcm-3 , lower than that of the associated ordinary chondrite meteorites, suggesting the presence of some macroporosity, but typical of S-types of the same size range (Carry [2012]. Planet. Space Sci. 73, 98-118). The present study is the first direct measurement of the size of a small main-belt binary. Although the interferometric observations of Isberga are at the edge of MIDI capabilities, the method described here is applicable to others suites of instruments (e.g., LBT, ALMA). [less ▲]Detailed reference viewed: 32 (2 ULg) WISE J072003.20-084651.2: an Old and Active M9.5 + T5 Spectral Binary 6 pc from the SunBurgasser, Adam J.; Gillon, Michaël ; Melis, Carl et alin Astronomical Journal (The) (2015), 149We report observations of the recently discovered, nearby late-M dwarf WISE J072003.20-084651.2. New astrometric measurements obtained with the TRAPPIST telescope improve the distance measurement to 6.0 ± ... [more ▼]We report observations of the recently discovered, nearby late-M dwarf WISE J072003.20-084651.2. New astrometric measurements obtained with the TRAPPIST telescope improve the distance measurement to 6.0 ± 1.0 pc and confirm the low tangential velocity (3.5 ± 0.6 km s[SUP]-1[/SUP]) reported by Scholz. Low-resolution optical spectroscopy indicates a spectral type of M9.5 and prominent Hα emission (< {{log }[SUB]10[/SUB]}{{L}[SUB]Hα [/SUB]}/{{L}[SUB]bol[/SUB]}> = -4.68 ± 0.06), but no evidence of subsolar metallicity or Li i absorption. Near-infrared spectroscopy reveals subtle peculiarities that can be explained by the presence of a T5 binary companion, and high-resolution laser guide star adaptive optics imaging reveals a faint (ΔH = 4.1) candidate source 0\buildrel{\prime\prime}\over{.} 14 (0.8 AU) from the primary. With high-resolution optical and near-infrared spectroscopy, we measure a stable radial velocity of +83.8 ± 0.3 km s[SUP]-1[/SUP], indicative of old disk kinematics and consistent with the angular separation of the possible companion. We measure a projected rotational velocity of v sin i = 8.0 ± 0.5 km s[SUP]-1[/SUP] and find evidence of low-level variabilty (˜1.5%) in a 13 day TRAPPIST light curve, but cannot robustly constrain the rotational period. We also observe episodic changes in brightness (1%-2%) and occasional flare bursts (4%-8%) with a 0.8% duty cycle, and order-of-magnitude variations in Hα line strength. Combined, these observations reveal WISE J0720-0846 to be an old, very low-mass binary whose components straddle the hydrogen burning minimum mass, and whose primary is a relatively rapid rotator and magnetically active. It is one of only two known binaries among late M dwarfs within 10 pc of the Sun, both of which harbor a mid T-type brown dwarf companion. We show that while this specific configuration is rare (≲1.6% probability), roughly 25% of binary companions to late-type M dwarfs in the local population are likely low-temperature T or Y brown dwarfs. Some of the data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. [less ▲]Detailed reference viewed: 18 (5 ULg) Rotation, spectral variability, magnetic geometry and magnetosphere of the Of?p star CPD -28° 2561Wade, G. A.; Barbá, R. H.; Grunhut, J. et alin Monthly Notices of the Royal Astronomical Society (2015), 447We report magnetic and spectroscopic observations and modelling of the Of?p star CPD -28° 2561. Using more than 75 new spectra, we have measured the equivalent width variations and examined the dynamic ... [more ▼]We report magnetic and spectroscopic observations and modelling of the Of?p star CPD -28° 2561. Using more than 75 new spectra, we have measured the equivalent width variations and examined the dynamic spectra of photospheric and wind-sensitive spectral lines. A period search results in an unambiguous 73.41 d variability period. High-resolution spectropolarimetric data analysed using least-squares deconvolution yield a Zeeman signature detected in the mean Stokes V profile corresponding to phase 0.5 of the spectral ephemeris. Interpreting the 73.41 d period as the stellar rotational period, we have phased the equivalent widths and inferred longitudinal field measurements. The phased magnetic data exhibit a weak sinusoidal variation, with maximum of about 565 G at phase 0.5, and a minimum of about -335 G at phase 0.0, with extrema approximately in phase with the (double-wave) Hα equivalent width variation. Modelling of the Hα equivalent width variation assuming a quasi-3D magnetospheric model produces a unique solution for the ambiguous couplet of inclination and magnetic obliquity angles: (i, β) or (β, i) = (35°, 90°). Adopting either geometry, the longitudinal field variation yields a dipole polar intensity B[SUB]d[/SUB] = 2.6 ± 0.9 kG, consistent with that obtained from direct modelling of the Stokes V profiles. We derive a wind magnetic confinement parameter η[SUB]*[/SUB] ≃ 100, leading to an Alfvén radius R[SUB]A[/SUB] ≃ 3-5R[SUB]*[/SUB], and a Kepler radius R[SUB]K[/SUB] ≃ 20R[SUB]*[/SUB]. This supports a physical scenario in which the Hα emission and other line variability have their origin in an oblique, corotating `dynamical magnetosphere' structure resulting from a magnetically channelled wind. Nevertheless, the details of the formation of spectral lines and their variability within this framework remain generally poorly understood. [less ▲]Detailed reference viewed: 10 (0 ULg) Spectroscopic variability of two Oe starsRauw, Grégor ; Morel, Thierry ; Nazé, Yaël et alin Astronomy and Astrophysics (2015), 575Context. The two Oe stars HD 45 314 and HD 60 848 have recently been found to exhibit very different X-ray properties: whilst HD 60 848 has an X-ray spectrum and the emission level typical of most OB ... [more ▼]Context. The two Oe stars HD 45 314 and HD 60 848 have recently been found to exhibit very different X-ray properties: whilst HD 60 848 has an X-ray spectrum and the emission level typical of most OB stars, HD 45 314 features a much harder and brighter X-ray emission, making it a so-called γ Cas analogue. Aims: Monitoring the optical spectra could provide hints towards the origin of these very different behaviours. Methods: We analyse a large set of spectroscopic observations of HD 45 314 and HD 60 848, extending over 20 years. We further attempt to fit the Hα line profiles of both stars with a simple model of emission line formation in a Keplerian disk. Results: Strong variations in the strengths of the Hα, Hβ, and He i λ 5876 emission lines are observed for both stars. In the case of HD 60 848, we find a time lag between the variations in the equivalent widths of these lines, which is currently not understood. The emission lines are double peaked with nearly identical strengths of the violet and red peaks. The Hα profile of this star can be successfully reproduced by our model of a disk seen under an inclination of 30°. In the case of HD 45 314, the emission lines are highly asymmetric and display strong line profile variations. We find a major change in behaviour between the 2002 outburst and the one observed in 2013. This concerns both the relationship between the equivalent widths of the various lines and their morphologies at maximum strength (double-peaked in 2002 versus single-peaked in 2013). Our simple disk model fails to reproduce the observed Hα line profiles of HD 45 314. Conclusions: Our results further support the interpretation that Oe stars do have decretion disks similar to those of Be stars. Whilst the emission lines of HD 60 848 are explained well by a disk with a Keplerian velocity field, the disk of HD 45 314 seems to have a significantly more complex velocity field that could be another signature of the phenomenon that produces its peculiar X-ray emission. [less ▲]Detailed reference viewed: 16 (3 ULg) Compte rendu de "Richard Mèmeteau, Pop culture. Réflexions sur les industries du rêve et l’invention des identités"Dozo, Björn-Olav in Lectures (2015)Detailed reference viewed: 19 (0 ULg) How well can cold dark matter substructures account for the observed radio flux-ratio anomaliesXu, Dandan; Sluse, Dominique ; Gao, Liang et alin Monthly Notices of the Royal Astronomical Society (2015), 447Discrepancies between the observed and model-predicted radio flux ratios are seen in a number of quadruply-lensed quasars. The most favoured interpretation of these anomalies is that cold dark matter (CDM ... [more ▼]Discrepancies between the observed and model-predicted radio flux ratios are seen in a number of quadruply-lensed quasars. The most favoured interpretation of these anomalies is that cold dark matter (CDM) substructures present in lensing galaxies perturb the lens potentials and alter image magnifications and thus flux ratios. So far no consensus has emerged regarding whether or not the predicted CDM substructure abundance fully accounts for the lensing flux anomaly observations. Accurate modelling relies on a realistic lens sample in terms of both the lens environment and internal structures and substructures. In this paper, we construct samples of generalized and specific lens potentials, to which we add (rescaled) subhalo populations from the galaxy-scale Aquarius and the cluster-scale Phoenix simulation suites. We further investigate the lensing effects from subhaloes of masses several orders of magnitude below the simulation resolution limit. The resulting flux-ratio distributions are compared to the currently best available sample of radio lenses. The observed anomalies in B0128+437, B0712+472 and B1555+375 are more likely to be caused by propagation effects or oversimplified/improper lens modelling, signs of which are already seen in the data. Among the quadruple systems that have closely located image triplets/pairs, the anomalous flux ratios of MG0414+0534 can be reproduced by adding CDM subhaloes to its macroscopic lens potential, with a probability of 5-20 per cent; for B0712+472, B1422+231, B1555+375 and B2045+265, these probabilities are only of a few per cent. We hence find that CDM substructures are unlikely to be the whole reason for radio flux anomalies. We discuss other possible effects that might also be at work. [less ▲]Detailed reference viewed: 33 (3 ULg) The HARPS search for southern extra-solar planets. XXXVI. Planetary systems and stellar activity of the M dwarfs GJ 3293, GJ 3341, and GJ 3543Astudillo-Defru, N.; Bonfils, X.; Delfosse, X. et alin Astronomy and Astrophysics (2015), 575Context. Planetary companions of a fixed mass induce reflex motions with a larger amplitude around lower-mass stars, which adds to making M dwarfs excellent targets for extra-solar planet searches. The ... [more ▼]Context. Planetary companions of a fixed mass induce reflex motions with a larger amplitude around lower-mass stars, which adds to making M dwarfs excellent targets for extra-solar planet searches. The most recent velocimeters with a stability of ~1 m s[SUP]-1[/SUP] can detect very low-mass planets out to the habitable zone of these stars. Low-mass small planets are abundant around M dwarfs, and most of the known potentially habitable planets orbit one of these cool stars.