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See detailAppropriateness criteria for cardiovascular imaging use in clinical practice: a position statement of the ESC/EACVI taskforce.
Garbi, Madalina; Habib, Gilbert; Plein, Sven et al

in European heart journal cardiovascular Imaging (2014), 15(5), 477-182

There is a growing interest from the scientific community in the appropriate use of cardiovascular imaging techniques for diagnosis and decision making in Europe. To develop appropriateness criteria for ... [more ▼]

There is a growing interest from the scientific community in the appropriate use of cardiovascular imaging techniques for diagnosis and decision making in Europe. To develop appropriateness criteria for cardiovascular imaging use in clinical practice in Europe, a dedicated taskforce has been appointed by the European Society of Cardiology (ESC) and the European Association of Cardiovascular Imaging (EACVI). The present paper describes the appropriateness criteria development process. [less ▲]

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See detailLA RADIOTHÉRAPIE DANS LE CANCER DU RECTUM : quand, comment et pourquoi ?
MARTINIVE, Philippe ULg; VAN DAELE, Daniel ULg; LENNERTS, Evelyne ULg et al

in Revue Médicale de Liège (2014), 69(Supp 1), 37-46

Depuis plusieurs décades, la radiothérapie préopéra - toire ou postopératoire joue un rôle important dans le contrôle local de l’adénocarcinome du rectum. Cette dernière décennie, avec la systématisation ... [more ▼]

Depuis plusieurs décades, la radiothérapie préopéra - toire ou postopératoire joue un rôle important dans le contrôle local de l’adénocarcinome du rectum. Cette dernière décennie, avec la systématisation de la chirurgie d’exérèse en totalité du mésorectum (TME), le profil de récidive locale du cancer du rectum a été fortement modifié. Dans un tel contexte, la place de la radiothérapie doit être réévaluée en tenant compte de ces modifications. Dans cet article, nous proposons de faire la revue des différentes grandes études concernant les techniques et les indications d’un traitement de radiothérapie pré- ou post opératoire dans le contexte d’une chirurgie rectale TME. [less ▲]

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See detailRecension: "Invloed van het Europese recht op het Belgisch privaatrecht"
Kohl, Benoît ULg

in Droit de la Consommation = Consumentenrecht [= DCCR] (2014), (102), 139-142

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See detailHighly dispersed Pt/C catalysts prepared by the Charge Enhanced DryImpregnation method
Cao Chongjiang; Yang Guang; Dubau Laetitia et al

in Applied Catalysis B : Environmental (2014), 150-151

tAn efficient method to synthesize highly dispersed Pt/carbon xerogel catalysts for Proton ExchangeMembrane fuel cell applications is described. The synthesis proceeds via the Charge Enhanced ... [more ▼]

tAn efficient method to synthesize highly dispersed Pt/carbon xerogel catalysts for Proton ExchangeMembrane fuel cell applications is described. The synthesis proceeds via the Charge Enhanced DryImpregnation method (CEDI), which combines dry impregnation with the Strong Electrostatic Adsorp-tion technique (SEA). The samples prepared via CEDI or SEA techniques were dried and reduced underhydrogen to obtain supported Pt nanoparticles. In order to increase the Pt mass fraction up to 10 wt.%,two successive impregnation-drying-reduction cycles were performed. The synthesized Pt nanoparticlesare homogeneously distributed on the carbon support and highly dispersed (mean Pt nanoparticle sizeof ca. 2 nm). The CEDI method is ideally suited to avoid Pt losses during the catalyst preparation. [less ▲]

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See detailUpdated standards and processes for accreditation of echocardiographic laboratories from The European Association of Cardiovascular Imaging.
Popescu, Bogdan A.; Stefanidis, Alexandros; Nihoyannopoulos, Petros et al

in European heart journal cardiovascular Imaging (2014)

Standards for echocardiographic laboratories were proposed by the European Association of Echocardiography (now the European Association of Cardiovascular Imaging) 7 years ago in order to raise standards ... [more ▼]

Standards for echocardiographic laboratories were proposed by the European Association of Echocardiography (now the European Association of Cardiovascular Imaging) 7 years ago in order to raise standards of practice and improve the quality of care. Criteria and requirements were published at that time for transthoracic, transoesophageal, and stress echocardiography. This paper reassesses and updates the quality standards to take account of experience and the technical developments of modern echocardiographic practice. It also discusses quality control, the incentives for laboratories to apply for accreditation, the reaccreditation criteria, and the current status and future prospects of the laboratory accreditation process. [less ▲]

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See detailImprovement of fermentative biohydrogen production by Clostridium butyricum CWBI1009 in sequenced-batch, horizontal fixed bed and biodisc-like anaerobic reactors with biomass retention
Hiligsmann, Serge ULg; Beckers, Laurent; Masset, Julien et al

in International Journal of Hydrogen Energy (2014), 39

A horizontal tubular fixed bed bioreactor (HFBR) and an anaerobic biodisc-like reactor (AnBDR) were designed to both fix Clostridium biomass and enable rapid transfer of the hydrogen produced to gas phase ... [more ▼]

A horizontal tubular fixed bed bioreactor (HFBR) and an anaerobic biodisc-like reactor (AnBDR) were designed to both fix Clostridium biomass and enable rapid transfer of the hydrogen produced to gas phase in order to decrease the strong effect of H2 partial pressure and H2 supersaturation on the performances of Clostridium strains. The highest H2 production rate (703 mL H2/L.h) and yield (302 mL/g glucose consumed i.e. 2.4 mol/mol) with the pure culture were recorded in the AnBDR with 300 mL culture medium (total volume 2.3 L) at pH 5.2 and a glucose loading rate of 2.87 g/L.h. These results are about 2.3 and 1.3-fold higher than those achieved in the same bioreactor with 500 mL liquid medium and with the same glucose consumption rate. Therefore, our experimentations and a short review of the literature reported in this paper emphasize the relevance of performing bioreactors with high L/G transfer. [less ▲]

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See detailAssociative learning of Nasonia vitripennis Walker (Hymenoptera: Pteromalidae) to methyldisulfanylmethane
Frederickx, Christine ULg; Verheggen, François ULg; Brostaux, Yves ULg et al

in Journal of Forensic Sciences (2014)

Traditional methods of volatile detection used by police typically consist of reliance on canine olfaction. However, dogs have some limitations such as cost of training and time of conditioning. The ... [more ▼]

Traditional methods of volatile detection used by police typically consist of reliance on canine olfaction. However, dogs have some limitations such as cost of training and time of conditioning. The possibility of using parasitic wasps for detecting explosives and narcotics has been developed. Moreover, wasps are cheap to produce and can be conditioned with impressive speed for a specific chemical-detection task. We examined the ability of Nasonia vitripennis Walker to learn and respond to methydisulfanylmethane (DMDS), a volatile discriminator of cadaver. The training aimed to form an association between an unconditioned stimulus (pupae) and the conditioned stimulus (odor source). After the training, the time spent of conditioned wasps in the DMDS chamber was measured. Statistical analysis showed that the increasing concentrations involved an increase in the time spent in the chamber containing DMDS. This study indicates that N. vitripennis can respond to DMDS, which provide further support for its development as a biological sensor. [less ▲]

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See detailStrategies to combine novel traits across countries: example of heat stress
Hammami, Hedi ULg; Vandenplas, Jérémie ULg; Carabaño, Maria Jesus et al

in Interbull Bulletin (2014), 48

Nowadays, novel traits are of great interest. However, phenotypes are siloed and mainly not shared. Heat stress is becoming problematic affecting animals’ performances and their well-being. Heat stress ... [more ▼]

Nowadays, novel traits are of great interest. However, phenotypes are siloed and mainly not shared. Heat stress is becoming problematic affecting animals’ performances and their well-being. Heat stress tolerance as a novel trait is only addressed by isolated within-country research studies. Integration and combination of local and foreign information sources is needed for better accuracy genetic evaluations. Therefore, this study was aimed to test the potential combination of sources of external information towards the evaluation of heat stress tolerance of dairy cattle. Long-term cow performances linked to environmental descriptors (weather parameters as proxy to climate change) collected over 10 years under the temperate conditions of the Walloon Region of Belgium and the hotter and warm Mediterranean conditions of Andalusia and Castile-La-Mancha Spanish regions were available. A total of 1,604,775 milk, fat, and protein test-day (TD) records linked to average daily temperature humidity (THI) values for 3-day lag before each TD were considered. Under a first strategy considering free-access to raw-data (phenotype and pedigree), a joint evaluation was firstly run using reaction norm models where production traits were considered as function of THI. A Belgian and a Spanish evaluation were also run using the same model. An alternative strategy considering only access to external information (i.e. regression coefficients for additive genetic effects (â and their associated REL)) was tested. In this case, foreign â and their REL resulting from the Spanish evaluation were first converted to the Belgian trait and thereafter integrated in the Belgian evaluation using a Bayesian approach. Rank correlations between regression coefficients, â (of the 1,104 bulls having daughters only in Spain) estimated by Belgian evaluation and â estimated by the joint evaluation were moderate (<=0.70). Corresponding rank correlations between â estimated by joint and Bayesian evaluations were significantly higher (ranging from 0.967 to 0.998), indicating that the Bayesian evaluation integrating external information was in good concordance with the joint evaluation. Results from this study indicated that the integration of external information via the Bayesian approach has a good potential to improve the genetic evaluation of sparse and siloed novel traits. [less ▲]

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See detailResistance of through-plate component in beam-to-column joints with circular hollow columns
Hoang, Van Long ULg; Demonceau, Jean-François ULg; Jaspart, Jean-Pierre ULg

in Journal of Constructional Steel Research (2014), 92

A configuration of beam-to-column joint with circular hollow section columns is proposed. A vertical plate, called through-plate, passing through the column is used to support the beams. In order to ... [more ▼]

A configuration of beam-to-column joint with circular hollow section columns is proposed. A vertical plate, called through-plate, passing through the column is used to support the beams. In order to facilitate connecting the beams, two horizontal plates, each side of the column, are welded to the upper side of the through-plate. The lower flanges of the steel beams are connected to the horizontal plates by bolts, and the upper flanges are attached to the concrete slab by shear connections. The joint is considered as hinges in the construction phase while semi-rigid and partial strength can be adopted for the joint behaviour during the exploitation time. A development on the through-plate component of the joint is presented in this paper. Global behaviour of the joint under hogging moment and shear force is analysed leading to a mechanical model of the through-plate component. Using the elastic buckling theory of plates, the analytical formulas for critical stresses of the through-plate are obtained. The coefficients taking into account boundary conditions, material plasticity and geometrical imperfection are determined by finite element analysis. The proposed model is validated by experimental results showing a good accuracy. The design guideline for the component is finally provided for the practical purpose. [less ▲]

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See detailLigand and solvation effects on the structural and electronic properties of small gold clusters
Dufour, F.; Fresch, Barbara ULg; Durupthy, O. et al

in Journal of Physical Chemistry C: Nanomaterials, Interfaces, and Hard Matter (2014), 118(8), 4362

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See detailDisease management patterns for postmenopausal women in Europe with hormone-receptor-positive, human epidermal growth factor receptor-2 negative advanced breast cancer.
Andre, Fabrice; Neven, Patrick; Marinsek, Nina et al

in Current medical research and opinion (2014)

Abstract Background: International guidelines for hormone-receptor-positive (HR+), human epidermal growth factor receptor-2 negative (HER2-) advanced breast cancer (BC) recommend sequential lines of ... [more ▼]

Abstract Background: International guidelines for hormone-receptor-positive (HR+), human epidermal growth factor receptor-2 negative (HER2-) advanced breast cancer (BC) recommend sequential lines of hormonal therapy (HT), and only recommend chemotherapy for patients with extensive visceral involvement or rapidly progressive disease. This study evaluated actual physician-reported treatments for advanced BC in Europe. Methods: We conducted a retrospective chart review of 355 postmenopausal women with HR+, HER2- advanced BC who progressed on >/=1 line of HT (adjuvant or advanced) and completed >/=1 line of chemotherapy (advanced). Treatment choice was evaluated for each line of therapy. Results: Of 355 patients, 111 (31%) received first-line chemotherapy, whereas 218 (61%) and 26 (7%) switched from HT to chemotherapy in second and third line, respectively. More patients receiving first-line HT had bone metastases (73% vs 27% chemotherapy). Patients treated with first-line chemotherapy had more brain (12% vs 3% HT) or extensive liver (13% vs 6% HT) metastases. Subgroup analysis of 188 patients who received first-line HT and had de novo advanced BC or relapsed/recurrent disease more than 1 year after adjuvant therapy found that the majority (89%; n = 167) of these patients switched to chemotherapy in second line. However, among these 167 patients, 27% had no significant changes in metastases between first and second line. Among the 73% of patients who had significant changes in metastases, 20% had no brain metastases or extensive visceral disease. Conclusions: Our study suggests that the guideline-recommended use of multiple HT lines is open to interpretation and that optimal treatment for European postmenopausal women with HR+, HER2- advanced BC who responded to HT may not be achieved. [less ▲]

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See detailDe Jacques Antoine aux éditions des Eperonniers : l'édition littéraire en Belgique au passé et au présent (première partie)
Durand, Pascal ULg; Habrand, Tanguy ULg

in Textyles : Revue des Lettres Belges de Langue Française (2014), 45

Première partie (POSITION ÉDITORIALE ET PATRIMONIALISATION LITTÉRAIRE : JACQUES ANTOINE) d'un article en deux volets dont le second porte sur la transition des éditions Jacques Antoine aux éditions des ... [more ▼]

Première partie (POSITION ÉDITORIALE ET PATRIMONIALISATION LITTÉRAIRE : JACQUES ANTOINE) d'un article en deux volets dont le second porte sur la transition des éditions Jacques Antoine aux éditions des Eperonniers et sur l'histoire et la politique éditoriale de cette dernière maison (CRÉATION CONTEMPORAINE ET POLITIQUES DU LIVRE : LYSIANE D’HAEYERE AUX ÉPERONNIERS). [less ▲]

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See detailDeconsecrating a doctrinal monument: Raymond M. Lemaire and the revisions of the Venice Charter
Houbart, Claudine ULg

in Change Over Time (2014), (fall),

Considering himself as the “main author” of the charter, Raymond M. Lemaire has been one of the first, together with Piero Gazzola, to plead for a revision of the document. As early as 1971, the two men ... [more ▼]

Considering himself as the “main author” of the charter, Raymond M. Lemaire has been one of the first, together with Piero Gazzola, to plead for a revision of the document. As early as 1971, the two men, respectively first Secretary General and President of ICOMOS, tended to launch a debate in favour of a better consideration of the social value of heritage, and the development of specific principles for historical cities conservation, to be included in the Venice charter. Lemaire’s recent experience in that field had indeed convinced him that, contrary to the assertion of article 14, “a literal application of principles valid for monuments, considered as such, is not always possible, nor desirable, for the ensembles”. The adoption of the Amsterdam declaration didn’t put an end to his efforts. Despite his unsuccessful attempt to get a revised version approved by the ICOMOS General assembly in Moscow (1978), R.M.Lemaire always remained critical towards the charter and the application of its principles in the field, underlining, in the eighties, its shortcomings in terms of cultural diversity and, in one of his last texts, in 1996, the negative effect of article 9, leading to the idea that “the mere essence of a conservation operation is a modernist intervention on the edifice or neighbourhood”. Beyond its interest for conservation history, the awareness of Lemaire’s early critical position towards the Venice Charter should inspire the current debates and help us overcome our reluctance to challenge the sacred principles of what we consider a doctrinal monument. [less ▲]

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See detailUncertainty assessment of ephemeral gully identification, characteristics and topographic threshold when using aerial photographs in agricultural settings
Maugnard, Alexandre; Cordonnier, Hélène; Degré, Aurore ULg et al

in EARTH SURFACE PROCESSES AND LANDFORMS (2014)

Manual digitizing on aerial photographs is still commonly used for characterizing gully erosion over large areas. Even when automated detection procedures are implemented, manual digitizing is frequently ... [more ▼]

Manual digitizing on aerial photographs is still commonly used for characterizing gully erosion over large areas. Even when automated detection procedures are implemented, manual digitizing is frequently being resorted to in order to constitute reference datasets used for training and validation. In both cases, manual digitizing entails some subjective decisions on behalf of the operator, which introduces uncertainty into the resulting datasets. To assess the magnitude of this uncertainty, 11 experienced operators were asked to digitize and classify ephemeral gullies (EGs) on cropland following a standardized methodology. The resulting 11 datasets were compared in terms of number, type and location of EGs. Furthermore, for EGs located on a welldefined runoff flow concentration axis, the slope versus contributing area topographic thresholds required for initiating gully channels were assessed using four thresholding methods, and compared across the 11 datasets. The operators identified 259 different EGs. However, the number (52–139) and sum total length (8.9–23.7 km) of EGs varied widely across operators. Only 34% of the EGs were digitized by more than half of the operators, and 7% were identified by all. Identification of EGs located on a well-defined flow concentration axis proved least subjective. The longer the EG and the more fields the EG crossed, the larger the number of operators that were able to identify it. EGs were also most easily identified when located in sugar beet fields as compared to other crops. EG classification and topographic threshold lines were also found to be strongly operator-dependent. Quantile regression appeared to be one of the most robust thresholding methods. Operator subjectivity when digitizing EGs on orthophotographs introduces uncertainty that should be taken into account in future remote sensing-based studies of EG erosion whenever they rely, in part or in full, on manual photograph interpretation. [less ▲]

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See detailMicrostructure and Mechanical Properties of a Mixed Si-Al TRIP-Assisted Steel Subjected to Continuous Galvanizing Heat Treatments
Mertens, Anne ULg; Bellhouse, Erika M.; McDermid, Joseph R.

in Materials Science & Engineering : A (2014), 608

Heat treatments with an isothermal bainitic transformation temperature of 465°C compatible with the continuous galvanizing process were performed on a 0.2C-1.5Mn-1.0Si-0.5Al (wt%) TRIP-assisted steel. The ... [more ▼]

Heat treatments with an isothermal bainitic transformation temperature of 465°C compatible with the continuous galvanizing process were performed on a 0.2C-1.5Mn-1.0Si-0.5Al (wt%) TRIP-assisted steel. The effect of intercritical annealing temperature and isothermal bainitic transformation (IBT) time at 465C on mechanical properties and microstructure were determined. The best combination of strength and ductility was obtained for the lower intercritical annealing temperature of 750°C for an isothermal bainitic transformation time of 90 s at 465°C. However, after intercritical annealing at a higher temperature of 797°C, optimum mechanical properties were obtained for a shorter isothermal bainitic transformation time of 60 s at 465°C, likely due to the lower C content of the intercritical austenite bringing about faster transformation kinetics. It was concluded that varying the intercritical temperature and IBT time can play an important role in the development of a suitable process window to obtain the desired mechanical properties in low alloy TRIP-assisted steels given the constraints associated with the continuous galvanizing process. [less ▲]

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See detailMesoporous Lithium Vanadium Oxide as Thin Film Electrode for Lithium-Ion Batteries: Comparison between Direct Synthesis of LiV2O5 and Electrochemical Lithium Intercalation in V2O5
Caes, Sébastien ULg; Arrebola, Jose Carlos; Krins, Natacha ULg et al

in Journal of Materials Chemistry A (2014), 2

Research in the field of lithium-ion batteries favours electrode materials with high surface area. In this context, this paper is dedicated to mesoporous thin films (MTFs) and compares the electrochemical ... [more ▼]

Research in the field of lithium-ion batteries favours electrode materials with high surface area. In this context, this paper is dedicated to mesoporous thin films (MTFs) and compares the electrochemical performance of g-LiV2O5 MTFs with post-synthesis electrochemical lithium intercalation in a-V2O5 MTFs. Formation of vanadium oxide MTFs by soft-chemistry is notoriously difficult. However, it is shown that wormlike vanadium oxide (V–O) and lithium vanadium oxide (Li–V–O) MTFs can be obtained on silicon substrates by a direct sol–gel soft-templating route (evaporation-induced micelle assembly) using a polystyrene-block-poly(ethylene oxide) (PS-b-PEO) structuring agent. Heat treatment for 1 minute at 400 C (Li–V–O system) or 30 minutes at 350 C (V–O system) leads to the crystallization of g-LiV2O5 or a-V2O5, respectively. These calcination conditions ensure the degradation of the structuring agent while preventing the collapse of the mesostructure, yielding MTFs with pore size diameter in the 30–35 nm range. Using the same set of synthesis conditions, films can be deposited on conductive glass substrates for electrochemical investigation: the a-V2O5 films display better specific capacities, while the cyclability is good for both compositions, even at a current density as high as 30 C-rate. [less ▲]

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See detailAnalysis of collagen preservation in bones recovered in archaeological contexts using NIR Hyperspectral Imaging
Vincke, Damien; Miller, Rebecca ULg; Stassart, Edith ULg et al

in Talanta (2014), 125

The scope of this article is to propose an innovative method based on Near Infrared Hyperspectral Chemical Imaging (NIR-HCI) to rapidly and non-destructively evaluate the relative degree of collagen ... [more ▼]

The scope of this article is to propose an innovative method based on Near Infrared Hyperspectral Chemical Imaging (NIR-HCI) to rapidly and non-destructively evaluate the relative degree of collagen preservation in bones recovered from archaeological contexts. This preliminary study has allowed the evaluation of the potential of the method using bone samples from the Early Upper Palaeolithic, Mesolithic and Neolithic periods at the site of Trou Al'Wesse in Belgium. NIR-HCI, combined with chemometric tools, has identified specific spectral bands characteristic of collagen. A chemometric model has been built using Partial Least Squares Discriminant Analysis (PLS-DA) to identify bones with and without collagen. This enables the evaluation of the degree of collagen preservation and homogeneity in bones within and between different strata, which has direct implications for archaeological applications (e.g., taphonomic analyses, assemblage integrity) and sample selection for sub- sequent analyses requiring collagen. Two archaeological applications are presented: comparison between sub-layers in an Early Upper Palaeolithic unit, and evaluation of the range of variability in collagen preservation within a single Holocene stratum. [less ▲]

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See detailIsolation and identification of dominant osmophilic Leuconostoc strains from traditional date product “Btana”
Abekhti, Abdelkader; Daube, Georges ULg; Kihal, M.

in International Food Research Journal [=IFRJ] (2014), 21(4), 1261-1268

The current study aimed to isolate and identify dominant osmophilic bacteria associated with a traditional date product named “Btana”, produced in south region of Maghreb countries. Samples were randomly ... [more ▼]

The current study aimed to isolate and identify dominant osmophilic bacteria associated with a traditional date product named “Btana”, produced in south region of Maghreb countries. Samples were randomly collected after two month of storage from tow villages (Mtarfat and Abani) in the Algerian southern department “Adrar”. A high osmotic pressure medium (MSE) was used for isolation of osmophilic bacteria, which were purified and examined for macroscopic and microscopic shape, Gram stain, catatalse, oxydase, acetoine and ADH production, reduction of nitrate, and motility. Isolates were then subculture on MRS medium for production of dextran, gas from glucose, growth in the presence of NaCl (3, 6.5 %) and sucrose (10, 20, 30, 40, and 50 %), pH tolerance (4.8, 6.5), growth temperature (10, 37, and 45°C) and thermo resistance (55°C for 15 min), enzymatic activity (proteolytic, lipolytic, hemolysis). Isolates were identified to specie’s level by sugar fermentation. Their growth and acidification kinetic were also studied. Results identified two species of Leuconostoc; Leuconostoc mesenteroides subsp. mesenteroides and Leuconostoc mesenteroides subsp. dextranicum. They show a high antibacterial activity against four indicator bacteria; Pseudomonas aeruginosa ATCC 27853, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923. [less ▲]

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See detailCervical cancer and HPV: Awareness and vaccine acceptability among parents in Morocco.
Mouallif, Mustapha; Bowyer, Harriet L.; Festali, Soukaina et al

in Vaccine (2014), 32(3), 409-16

Cervical cancer is a major public health concern in Morocco where it represents the second most common and lethal cancer in women. Human papillomavirus (HPV) vaccines have been licensed in Morocco since ... [more ▼]

Cervical cancer is a major public health concern in Morocco where it represents the second most common and lethal cancer in women. Human papillomavirus (HPV) vaccines have been licensed in Morocco since 2008 but there are no available data on their acceptability. This study aimed to assess awareness of HPV and the vaccine, and to identify factors associated with acceptability of the vaccine among parents in Morocco. We carried out a questionnaire-based survey using face-to-face interviews in a sample of 852 parents (670 mothers and 182 fathers) with at least one unmarried daughter </=26 years. We collected data within public and private health centres and clinics in four regions in Morocco between July and August 2012. The main outcome measure was parental acceptability of the HPV vaccine for their daughter(s). Responses revealed very low awareness of HPV infection (4.7%) and the HPV vaccine (14.3%). None of the participants had vaccinated their daughter(s) against HPV and vaccine acceptability was low among mothers (32%) and fathers (45%). Higher education and income, previous awareness of the HPV vaccine and endorsement of the belief that a recommendation from the Ministry of Health or a doctor to have the vaccine would be encouraging, were associated with mothers' HPV vaccine acceptability. Non-acceptability among mothers was associated with having more than two daughters, believing the vaccine was expensive, lack of information and believing that whatever happens to an individual's health is God's will. The only factor associated with the fathers' acceptability of the vaccine was the cost of the vaccine. Increasing HPV and HPV vaccine awareness through educational campaigns, along with active recommendation by physicians and a publically funded vaccination programme could increase parental acceptability of the HPV vaccine in Morocco. [less ▲]

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See detailHow Does Pollen Chemistry Impact Development and Feeding Behaviour of Polylectic Bees?
Vanderplanck, Maryse; Moerman, Romain; Rasmont, Pierre et al

in PLoS ONE (2014), 9(1), 9

Larvae and imagos of bees rely exclusively on floral rewards as a food source but host-plant range can vary greatly among bee species. While oligolectic species forage on pollen from a single family of ... [more ▼]

Larvae and imagos of bees rely exclusively on floral rewards as a food source but host-plant range can vary greatly among bee species. While oligolectic species forage on pollen from a single family of host plants, polylectic bees, such as bumblebees, collect pollen from many families of plants. These polylectic species contend with interspecific variability in essential nutrients of their host-plants but we have only a limited understanding of the way in which chemicals and chemical combinations influence bee development and feeding behaviour. In this paper, we investigated five different pollen diets (Calluna vulgaris, Cistus sp., Cytisus scoparius, Salix caprea and Sorbus aucuparia) to determine how their chemical content affected bumblebee colony development and pollen/syrup collection. Three compounds were used to characterise pollen content: polypeptides, amino acids and sterols. Several parameters were used to determine the impact of diet on micro-colonies: (i) Number and weight of larvae (total and mean weight of larvae), (ii) weight of pollen collected, (iii) pollen efficacy (total weight of larvae divided by weight of the pollen collected) and (iv) syrup collection. Our results show that pollen collection is similar regardless of chemical variation in pollen diet while syrup collection is variable. Micro-colonies fed on S. aucuparia and C. scoparius pollen produced larger larvae (i.e. better mates and winter survivors) and fed less on nectar compared to the other diets. Pollen from both of these species contains 24-methylenecholesterol and high concentrations of polypeptides/total amino acids. This pollen nutritional “theme” seems therefore to promote worker reproduction in B. terrestris micro-colonies and could be linked to high fitness for queenright colonies. As workers are able to selectively forage on pollen of high chemical quality, plants may be evolutionarily selected for their pollen content, which might attract and increase the degree of fidelity of generalist pollinators, such as bumblebees. [less ▲]

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See detailIs Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)?
van Elk, C. E.; van de Bildt, M. W. G.; Jauniaux, Thierry ULg et al

in Veterinary pathology (2014)

The virulence of morbilliviruses for toothed whales (odontocetes) appears to differ according to host species. In 4 species of odontocetes, morbilliviruses are highly virulent, causing large-scale ... [more ▼]

The virulence of morbilliviruses for toothed whales (odontocetes) appears to differ according to host species. In 4 species of odontocetes, morbilliviruses are highly virulent, causing large-scale epizootics with high mortality. In 8 other species of odontocetes, including white-beaked dolphins (Lagenorhynchus albirostris), morbilliviruses have been found as an incidental infection. In these species, the virulence of morbilliviruses is not clear. Therefore, the admission of 2 white-beaked dolphins with morbillivirus infection into a rehabilitation center provided a unique opportunity to investigate the virulence of morbillivirus in this species. By phylogenetic analysis, the morbilliviruses in both animals were identified as a dolphin morbillivirus (DMV) most closely related to that detected in a white-beaked dolphin in Germany in 2007. Both animals were examined clinically and pathologically. Case No. 1 had a chronic neural DMV infection, characterized by polioencephalitis in the cerebrum and morbillivirus antigen expression limited to neurons and glial cells. Surprisingly, no nervous signs were observed in this animal during the 6 months before death. Case No. 2 had a subacute systemic DMV infection, characterized by interstitial pneumonia, leucopenia, lymphoid depletion, and DMV antigen expression in mononuclear cells and syncytia in the lung and in mononuclear cells in multiple lymphoid organs. Cause of death was not attributed to DMV infection in either animal. DMV was not detected in 2 contemporaneously stranded white-beaked dolphins. Stranding rate did not increase in the region. These results suggest that DMV is not highly virulent for white-beaked dolphins. [less ▲]

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See detailLong-term fracture rates seen with continued ibandronate treatment : pooled analysis of DIVA and MOBILE long-term extension studies
Miller, PD; Recker, RR; Harris, S et al

in Osteoporosis International (2014), 25(1), 349-357

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See detailThe tumbling spin state of (99942) Apophis
Pravec, P; Scheirich, P; Ďurech, J et al

in Icarus (2014), 233

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See detailIncrease in dimethylsulfide (DMS) emissions due to eutrophication of coastal waters offsets their reduction due to ocean acidification
Gypens, N; Borges, Alberto ULg

in Frontiers in Marine Science - Marine Ecosystem Ecology (2014), 1(4),

Available information from manipulative experiments suggested that the emission of dimethylsulfide (DMS) would decrease in response to the accumulation of anthropogenic CO2 in the ocean (ocean ... [more ▼]

Available information from manipulative experiments suggested that the emission of dimethylsulfide (DMS) would decrease in response to the accumulation of anthropogenic CO2 in the ocean (ocean acidification). However, in coastal environments, the carbonate chemistry of surface waters was also strongly modified by eutrophication and related changes in biological activity (increased primary production and change in phytoplankton dominance) during the last 50 years. Here, we tested the hypothesis that DMS emissions in marine coastal environments also strongly responded to eutrophication in addition to ocean acidification at decadal timescales. We used the R-MIRO-BIOGAS model in the eutrophied Southern Bight of the North Sea characterized by intense blooms of Phaeocystis that are high producers of dimethylsulfoniopropionate (DMSP), the precursor of DMS. We showed that, for the period from 1951 to 2007, eutrophication actually led to an increase of DMS emissions much stronger than the response of DMS emissions to ocean acidification. [less ▲]

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See detailLow temperature crystallization of yttrium orthoferrite by organic acid-assisted sol-gel synthesis
Stevens, Frédéric ULg; Cloots, Rudi ULg; Poelman, D. et al

in Materials Letters (2014), 114

Yttrium orthoferrite (YFeO3) is a promising material for visible light photocatalytic applications due to its band gap of 2.2-2.6 eV. However, during the synthesis of YFeO3, unwanted composition can be ... [more ▼]

Yttrium orthoferrite (YFeO3) is a promising material for visible light photocatalytic applications due to its band gap of 2.2-2.6 eV. However, during the synthesis of YFeO3, unwanted composition can be obtained and the crystallization requires temperatures as high as 850 C. Powders of YFeO3 were prepared using a sol-gel method with and without organic acids (citric acid, tartaric acid, malonic acid and oxalic acid) used as organic modifiers. The band gap of these powders was measured by diffuse reflection spectroscopy, and the crystallinity and crystalline phase content were characterized by X-ray diffraction. Organic acids allow a higher purity and facilitate crystallization. This work aims to produce YFeO3 powders at the lowest possible temperature. Citric acid was found to be the best additive: it reduces the crystallization temperature below 450 C. This opens new perspectives such as the deposition of crystalline YFeO3 thin films onto conductive glass for water-splitting applications. © 2013 Elsevier B.V. [less ▲]

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See detailInitial uncertainty in Pavlovian reward prediction persistently elevates incentive salience and extends sign-tracking to normally unattractive cues
Robinson, Mike J.F.; Anselme, Patrick ULg; Fischer, Adam M. et al

in Behavioural Brain Research (2014), 266(1), 119-130

Uncertainty is a component of many gambling games and may play a role in incentive motivation and cue attraction. Uncertainty can increase the attractiveness for predictors of reward in the Pavlovian ... [more ▼]

Uncertainty is a component of many gambling games and may play a role in incentive motivation and cue attraction. Uncertainty can increase the attractiveness for predictors of reward in the Pavlovian procedure of autoshaping, visible as enhanced sign-tracking (or approach and nibbles) by rats of a metal lever whose sudden appearance acts as a conditioned stimulus (CS+) to predict sucrose pellets as an unconditioned stimulus (UCS). Here we examined how reward uncertainty might enhance incentive salience as sign-tracking both in intensity and by broadening the range of attractive CS+s. We also examined whether initially-induced uncertainty enhancements of CS+ attraction can endure beyond uncertainty itself, and persist even when Pavlovian prediction becomes 100% certain. Our results show that uncertainty can broaden incentive salience attribution to make CS cues attractive that would otherwise not be (either because they are too distal from reward or too risky to normally attract sign-tracking). In addition, uncertainty enhancement of CS+ incentive salience, once induced by initial exposure, persisted even when Pavlovian CS-UCS correlations later rose toward 100% certainty in prediction. Persistence suggests an enduring incentive motivation enhancement potentially relevant to gambling, which in some ways resembles incentive-sensitization. Higher motivation to uncertain CS+s leads to more potent attraction to these cues when they predict the delivery of uncertain rewards. In humans, those cues might possibly include the sights and sounds associated with gambling, which contribute a major component of the play immersion experienced by problematic gamblers. [less ▲]

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See detailChemical composition, cytotoxicity and in vitro antitrypanosomal and antiplasmodial activity of the essential oils of four Cymbopogon species from Benin.
Kpoviessi, Salome; Bero, Joanne; Agbani, Pierre et al

in Journal of ethnopharmacology (2014), 151

ETHNOPHARMACOLOGICAL RELEVANCE: Cymbopogon species are largely used in folk medicine for the treatment of many diseases some of which related to parasitical diseases as fevers and headaches. As part of ... [more ▼]

ETHNOPHARMACOLOGICAL RELEVANCE: Cymbopogon species are largely used in folk medicine for the treatment of many diseases some of which related to parasitical diseases as fevers and headaches. As part of our research on antiparasitic essential oils from Beninese plants, we decided to evaluate the in vitro antiplasmodial and antitrypanosomal activities of essential oils of four Cymbopogon species used in traditional medicine as well as their cytotoxicity. MATERIALS AND METHODS: The essential oils of four Cymbopogon species Cymbopogon citratus (I), Cymbopogon giganteus (II), Cymbopogon nardus (III) and Cymbopogon schoenantus (IV) from Benin obtained by hydrodistillation were analysed by GC/MS and GC/FID and were tested in vitro against Trypanosoma brucei brucei and Plasmodium falciparum respectively for antitrypanosomal and antiplasmodial activities. Cytotoxicity was evaluated in vitro against Chinese Hamster Ovary (CHO) cells and the human non cancer fibroblast cell line (WI38) through MTT assay to evaluate the selectivity. RESULTS: All tested oils showed a strong antitrypanosomal activity with a good selectivity. Sample II was the most active against Trypanosoma brucei brucei and could be considered as a good candidate. It was less active against Plasmodium falciparum. Samples II, III and IV had low or no cytotoxicity, but the essential oil of Cymbopogon citraus (I), was toxic against CHO cells and moderately toxic against WI38 cells and needs further toxicological studies. Sample I (29 compounds) was characterised by the presence as main constituents of geranial, neral, beta-pinene and cis-geraniol; sample II (53 compounds) by the presence of trans-p-mentha-1(7),8-dien-2-ol, trans-carveol, trans-p-mentha-2,8-dienol, cis-p-mentha-2,8-dienol, cis-p-mentha-1(7),8-dien-2-ol, limonene, cis-carveol and cis-carvone; sample III (28 compounds) by beta-citronellal, nerol, beta-citronellol, elemol and limonene and sample IV (41 compounds) by piperitone, (+)-2-carene, limonene, elemol and beta-eudesmol. CONCLUSIONS: Our study shows that essential oils of Cymbopogon genus can be a good source of antitrypanosomal agents. This is the first report on the activity of these essential oils against Trypanosoma brucei brucei, Plasmodium falciparum and analysis of their cytotoxicity. [less ▲]

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See detailcomment j'explore les infections nosocomiales en néonatologie
Dachy, Angélique ULg; Battisti, Oreste ULg

in Revue Médicale de Liège (2014)

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See detailValidation d’un test d’inhibition auprès d’enfants présentant un trouble déficitaire de l’attention avec/sans hyperactivité
Catale, Corinne ULg; Lejeune, Caroline ULg; Schmitz, Xavier ULg et al

in Canadian Journal of Behavioural Science = Revue Canadienne des Sciences du Comportement (2014), 46(1), 66-72

The objective of this study was to assess the development of inhibition in 5-11 years old children with the “Stroop fruit” task (see Archibald & Kerns, 1999; Catale & Meulemans, 2005) and to examine the ... [more ▼]

The objective of this study was to assess the development of inhibition in 5-11 years old children with the “Stroop fruit” task (see Archibald & Kerns, 1999; Catale & Meulemans, 2005) and to examine the clinical value of this tool. 346 French-speaking children without any developmental disorders or learning disabilities were included in this study. A clinical group of 25 children with attention deficit and hyperactivity disorder was also assessed with this task. Developmental analyses on age groups show an enhancement of performance in the interference condition between 5 and 8 years old. Furthermore, results also show that the clinical group performed significantly less accurately that the control group for the interference condition, which confirms the clinical interest of this tool. [less ▲]

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See detailRepublished: Value of biomarkers in osteoarthritis: current status and perspectives.
Lotz, M.; Martel-Pelletier, J.; Christiansen, C. et al

in Postgraduate Medical Journal (2014), 90(1061), 171-8

Osteoarthritis affects the whole joint structure with progressive changes in cartilage, menisci, ligaments and subchondral bone, and synovial inflammation. Biomarkers are being developed to quantify joint ... [more ▼]

Osteoarthritis affects the whole joint structure with progressive changes in cartilage, menisci, ligaments and subchondral bone, and synovial inflammation. Biomarkers are being developed to quantify joint remodelling and disease progression. This article was prepared following a working meeting of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis convened to discuss the value of biochemical markers of matrix metabolism in drug development in osteoarthritis. The best candidates are generally molecules or molecular fragments present in cartilage, bone or synovium and may be specific to one type of joint tissue or common to them all. Many currently investigated biomarkers are associated with collagen metabolism in cartilage or bone, or aggrecan metabolism in cartilage. Other biomarkers are related to non-collagenous proteins, inflammation and/or fibrosis. Biomarkers in osteoarthritis can be categorised using the burden of disease, investigative, prognostic, efficacy of intervention, diagnostic and safety classification. There are a number of promising candidates, notably urinary C-terminal telopeptide of collagen type II and serum cartilage oligomeric protein, although none is sufficiently discriminating to differentiate between individual patients and controls (diagnostic) or between patients with different disease severities (burden of disease), predict prognosis in individuals with or without osteoarthritis (prognostic) or perform so consistently that it could function as a surrogate outcome in clinical trials (efficacy of intervention). Future avenues for research include exploration of underlying mechanisms of disease and development of new biomarkers; technological development; the 'omics' (genomics, metabolomics, proteomics and lipidomics); design of aggregate scores combining a panel of biomarkers and/or imaging markers into single diagnostic algorithms; and investigation into the relationship between biomarkers and prognosis. [less ▲]

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See detailOptimization of a formic/acetic acid delignification treatment on beech wood and its influence on the structural characteristics of the extracted lignins
Simon, Mathilde; Brostaux, Yves ULg; Vanderghem, Caroline ULg et al

in Journal of Chemical Technology & Biotechnology (2014), 89(1), 128-136

Background In order to replace petrochemicals by bio-based lignin products in a lot of high value-added applications, a formic/acetic acid treatment was adapted to beech wood (Fagus sylvatica L.) for ... [more ▼]

Background In order to replace petrochemicals by bio-based lignin products in a lot of high value-added applications, a formic/acetic acid treatment was adapted to beech wood (Fagus sylvatica L.) for lignin extraction. Results Beech wood particles were delignified at atmospheric pressure by a formic acid/acetic acid/water mixture. Cooking time and temperature were optimized for delignification, pulp yield and 2-furfural concentration. Response surface design analysis revealed that delignification yield increased with cooking time and temperature. Conclusion The multi-criteria optimization of delignification was used to find the ideal cooking conditions (5h07 min, 104.2°C) which could be satisfactory for the maximization of delignification (70.5%) and pulp yield (58.7%) and, to a lesser extent, for the minimization of 2-furfural production. Treatment conditions were found to influence the chemical structure of extracted lignins. Cooking time and temperature influenced inversely lignin molecular weights. [less ▲]

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See detailCardiovascular imaging.
Lancellotti, Patrizio ULg; Habib, Gilbert; Negila, Danilo et al

in European heart journal (2014), 35(18), 1161-2

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See detailHigh Diversity in Cretaceous Ichthyosaurs from Europe Prior to Their Extinction
Fischer, Valentin ULg; Bardet, Nathalie; Guiomar, Myette et al

in PLoS ONE (2014), 9(1), 84709

Background: Ichthyosaurs are reptiles that inhabited the marine realm during most of the Mesozoic. Their Cretaceous representatives have traditionally been considered as the last survivors of a group ... [more ▼]

Background: Ichthyosaurs are reptiles that inhabited the marine realm during most of the Mesozoic. Their Cretaceous representatives have traditionally been considered as the last survivors of a group declining since the Jurassic. Recently, however, an unexpected diversity has been described in Upper Jurassic–Lower Cretaceous deposits, but is widely spread across time and space, giving small clues on the adaptive potential and ecosystem control of the last ichthyosaurs. The famous but little studied English Gault Formation and ‘greensands’ deposits (the Upper Greensand Formation and the Cambridge Greensand Member of the Lower Chalk Formation) offer an unprecedented opportunity to investigate this topic, containing thousands of ichthyosaur remains spanning the Early–Late Cretaceous boundary. Methodology/Principal findings: To assess the diversity of the ichthyosaur assemblage from these sedimentary bodies, we recognized morphotypes within each type of bones. We grouped these morphotypes together, when possible, by using articulated specimens from the same formations and from new localities in the Vocontian Basin (France); a revised taxonomic scheme is proposed. We recognize the following taxa in the ‘greensands’: the platypterygiines ‘Platypterygius’ sp. and Sisteronia seeleyi gen. et sp. nov., indeterminate ophthalmosaurines and the rare incertae sedis Cetarthrosaurus walkeri. The taxonomic diversity of late Albian ichthyosaurs now matches that of older, well-known intervals such as the Toarcian or the Tithonian. Contrasting tooth shapes and wear patterns suggest that these ichthyosaurs colonized three distinct feeding guilds, despite the presence of numerous plesiosaur taxa. Conclusion/Significance: Western Europe was a diversity hot-spot for ichthyosaurs a few million years prior to their final extinction. By contrast, the low diversity in Australia and U.S.A. suggests strong geographical disparities in the diversity pattern of Albian–early Cenomanian ichthyosaurs. This provides a whole new context to investigate the extinction of these successful marine reptiles, at the end of the Cenomanian. [less ▲]

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See detailIdentification of pregnancy-associated glycoproteins and alpha-fetoprotein in fallow deer (Dama dama) placenta
Bériot, Mathilde ULg; Tchimbou Njanjo, Aline Flora ULg; Barbato, Olimpia et al

in Acta Veterinaria Scandinavica (2014), 56(4), 1-11

Background: This paper describes the isolation and characterization of pregnancy-associated glycoproteins (PAG) from fetal cotyledonary tissue (FCT) and maternal caruncular tissue (MCT) collected from ... [more ▼]

Background: This paper describes the isolation and characterization of pregnancy-associated glycoproteins (PAG) from fetal cotyledonary tissue (FCT) and maternal caruncular tissue (MCT) collected from fallow deer (Dama dama) pregnant females. Proteins issued from FCT and MCT were submitted to affinity chromatographies by using Vicia villosa agarose (VVA) or anti-bovine PAG-2 (R#438) coupled to Sepharose 4B gel. Finally, they were characterized by SDSPAGE and N-terminal microsequencing. Results: Four distinct fallow deer PAG (fdPAG) sequences were identified and submitted to Swiss-Prot database. Comparison of fdPAG with PAG sequences identified in other ruminant species exhibited 64 to 83% identity. Additionally, alpha-fetoprotein was identified in fetal and maternal tissues. Conclusion: Our results demonstrate the efficacy of VVA and bovine PAG-2 affinity chromatographies for the isolation of PAG molecules expressed in deer placenta. This is the first report giving four specific amino acid sequences of PAG isolated from feto-maternal junction (FCT and MCT) in the Cervidae family. [less ▲]

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See detailPortrait photographique d’écrivain et newsmagazine. Pour une approche rhétorique de l’événementialité du littéraire
Provenzano, François ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2014), 14

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See detailInteractions of subunits Asa2, Asa4 and Asa7 in the peripheral stalk of the mitochondrial ATP synthase of the chlorophycean alga Polytomella sp.
Miranda-Astudillo, Hector; Cano-Estrada, Araceli; Vazquez-Acevedo, Miriam et al

in Biochimica et Biophysica Acta-Bioenergetics (2014), 1837

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See detailEffect of misalignment on pull-off test results: numerical and experimental assessments
Courard, Luc ULg; Bissonnette, Benoît; Garbacz, Andrzej et al

in ACI Materials Journal (2014), 111(2), 153-162

The successful application of a concrete repair system is often evaluated through pull-off testing. For such in-situ quality control (QC) testing, the inherent risk of misalignment might affect the ... [more ▼]

The successful application of a concrete repair system is often evaluated through pull-off testing. For such in-situ quality control (QC) testing, the inherent risk of misalignment might affect the recorded value and eventually make a difference in the acceptance of the work. So far, the issue of eccentricity in pull-off testing has been ignored in field practice, because it is seen as an academic issue. This paper presents the results of a project intended to quantify the effect of misalignment on pull-off tensile strength evaluation and provide a basis for improving QC specifications if necessary. The test program consisted first in an analytical evaluation of the problem through 2-D FEM simulations and, in a second phase, in laboratory experiments in which the test variables were the misalignment angle (0°, 2° and 4°) and the coring depth (15 mm [1.18 in.], 30 mm [2.36 in.]). It was found that calculations provide a conservative but realistic lower bound limit for evaluation the influence of misalignment upon pull-off test results: a 2° misalignment can be expect to yield a pull-off strength reduction of 7 to 9 % respectively for 15-mm [1.18-in.] and 30-mm [2.36-in.] coring depths, and the corresponding decrease resulting from a 4° misalignment reach between 13 and 16%; From a practical standpoint, the results generated in this study indicate that when specifying a pull-off strength limit in the field, the value should be increased (probable order of magnitude: 15%) to take into account the potential reduction due to testing misalignment. [less ▲]

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See detailPlant selection for nest building by western lowland gorillas in Cameroon
Willie, Jacob; Tagg, Nikki; Petre, Charles-Albert ULg et al

in Primates : Journal of Primatology (2014)

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See detailExercise Echocardiography in Asymptomatic Patients with Severe Aortic Stenosis and Preserved Left Ventricular Ejection Fraction.
Henri, Christine; Lancellotti, Patrizio ULg

in Journal of cardiovascular ultrasound (2014), 22(1), 1-5

The management of asymptomatic patients with severe aortic stenosis (AS) remains controversial. Recent series reported that early aortic valve replacement might be associated with improved clinical ... [more ▼]

The management of asymptomatic patients with severe aortic stenosis (AS) remains controversial. Recent series reported that early aortic valve replacement might be associated with improved clinical outcomes. However, the risk-benefit ratio should be carefully evaluated and early surgery only be proposed to a subset of asymptomatic patients considered at higher risk. Exercise echocardiography can help unmask symptomatic patients combined with assessment of the hemodynamic consequences of AS. Recent studies have demonstrated that exercise echocardiography can provide incremental prognostic value to identify patients who may benefit most from early surgery. In "truly" asymptomatic patients, an increase in mean aortic gradient >/= 18-20 mmHg, a limited left ventricular contractile reserve or a pulmonary hypertension during exercise are predictive parameters of adverse cardiac events. Exercise echocardiography is low-cost, safe and available in many referral centers, and does not expose patients to radiation. The purpose of this article is to describe the role of exercise testing and echocardiography in the management of asymptomatic patients with severe AS and preserved left ventricular ejection fraction. [less ▲]

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See detailRelationship between glucose and pancreatic hormones during the embryonic and postnatal phase in chickens
Franssens, L.; Buyse, J.; Decuypere, E. et al

in Avian Biology Research (2014), 7

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See detailV. Van Saaze, Installation Art and the Museum : Presentation and Conservation of Changing Artworks
D'Haenens, Manon ULg

in CeROArt : Conservation, Exposition, Restauration d'Objets d'Art (2014), (9),

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See detailAntioxidant capacity of small dark fruits. Influence of cultivars and harvest time
Kevers, Claire ULg; PINCEMAIL, Joël ULg; Defraigne, Jean-Olivier ULg et al

in Journal of Berry Research (2014)

BACKGROUND: Small dark fruits represent one of the most important sources of bioactive compounds with antioxidant capacity in the human diet. The content of health-promoting antioxidants in these fruits ... [more ▼]

BACKGROUND: Small dark fruits represent one of the most important sources of bioactive compounds with antioxidant capacity in the human diet. The content of health-promoting antioxidants in these fruits may be important information to take into account when a fruit producer has to choose which cultivar to grow. OBJECTIVE: It is important to know how antioxidant capacity and antioxidant compounds as total phenolics and ascorbic acid vary between 9 small dark fruit species and for each species among cultivars (2 to 10 per species). METHODS: The antioxidant capacity (ORAC assay), total phenolic (Folin-Ciocalteu) and ascorbic acid content were measured in 9 fruits (plums, blackcurrants, blackberries, blueberries, cherries, redcurrants, raspberries, white currants and gooseberries) / 42 cultivars harvested at maturity during their high production period. RESULTS: The comparison of the average of the various cultivars of each small fruits showed that blackcurrants had the best antioxidant capacity (with plums), the highest ascorbic acid content and the highest total phenolic content (with blackberries). The present study shows that total phenolic compounds, ascorbic acid and antioxidant capacity strongly differed between genotypes of each small dark fruits. Other parameters as harvest time, culture conditions and maturity degree at the harvest may also influence the antioxidant capacity of small fruits. CONCLUSION: Among small dark fruits, blackcurrants have high qualities. Choices of variety, harvest time and maturity degree are important for all fruits. [less ▲]

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See detailPassive designs and strategies for low-cost housing using simulation-based optimization and different thermal comfort criteria
Nguyen, Anh Tuan ULg; Reiter, Sigrid ULg

in Journal of Building Performance Simulation [=JBPS] (2014), 7(1), 68-81

An optimum design of low-cost housing offers low-income urban inhabitants great opportunities to obtain a shelter at an affordable price and acceptable indoor thermal conditions. In this paper, the design ... [more ▼]

An optimum design of low-cost housing offers low-income urban inhabitants great opportunities to obtain a shelter at an affordable price and acceptable indoor thermal conditions. In this paper, the design and operation of a low-cost dwelling were numerically optimized using a simulation-based approach. Three multi-objective cost functions including construction cost, thermal comfort performance and 50-year operating cost were applied for naturally ventilated and air-conditioned buildings. Thermal environment inside the house was controlled and assessed by two thermal comfort models. Optimization problems which consist of 18 design parameters and 6 ventilation strategies were examined by two population-based probabilistic optimization algorithms (particle swarm optimization and hybrid algorithm). Optimum designs corresponding to each objective function, differences in optimal solutions, energy saving by the adaptive comfort approach and optimization effectiveness were outlined. The optimization method used in this paper shows a considerable potential of comfort improvement, energy saving and operating cost reduction. [less ▲]

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See detailMyeloperoxidase and its products in synovial fluid of patients with treated or untreated rheumatoid arthritis.
Nzeusseu Toukap, A.; Delporte, C.; Noyon, C. et al

in Free radical research (2014), 48(4), 461-5

Abstract Objective. Plasma and synovial myeloperoxidase (MPO) and its products were strongly associated with osteoarthritis (OA) and rheumatoid arthritis (RA). In addition, it is well known that there is ... [more ▼]

Abstract Objective. Plasma and synovial myeloperoxidase (MPO) and its products were strongly associated with osteoarthritis (OA) and rheumatoid arthritis (RA). In addition, it is well known that there is a link between oxidative stress and cytokines. The present study aims at investigating the link between synovial MPO (and its products), interleukin (IL)-18, which is involved in the degradation of articular cartilage in RA, and IL-8, which is involved in recruitment and activation of neutrophils during inflammation. Effects of the treatment of RA on the biological parameters were also investigated. Methods. Patients (n = 105) were studied including 39 patients with OA, 33 with RA and 33 with RA receiving a specific treatment. Disease activity score (DAS-28) was calculated whereas MPO antigen/activity, neutrophils, chloro-tyrosine (Cl-Tyr), homocitrulline (Hcit), IL-8, and IL-18 were measured in synovial fluid (SF) and CRP was measured in serum. Results. DAS-28 and CRP levels were not significantly different between groups. MPO activity, and MPO, Cl-Tyr, and Hcit levels were significantly higher in SF of RA patients than OA patients. MPO specific activity (MPO activity/antigen ratio) was significantly lower in treated than in untreated RA patients as was IL-8. MPO activity and concentration were correlated with IL-8 and IL-18 in untreated but not in treated RA patients. Conclusions. MPO level is related to IL-8 and IL-18 levels in untreated RA patients. A link has been shown between treatment and decrease of IL-8, MPO specific activity and Hcit in SF. The causal role of MPO in SF inflammation and how treatment can affect MPO specific activity need further investigations. [less ▲]

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See detailAssessing the potential of an algorithm based on mean climatic data to predict wheat yield
Dumont, Benjamin ULg; Leemans, Vincent ULg; Ferrandis, Salvador et al

in Precision Agriculture (2014)

The real-time non-invasive determination of crop biomass and yield prediction is one of the major challenges in agriculture. An interesting approach lies in using process-based crop yield models in ... [more ▼]

The real-time non-invasive determination of crop biomass and yield prediction is one of the major challenges in agriculture. An interesting approach lies in using process-based crop yield models in combination with real-time monitoring of the input climatic data of these models, but unknown future weather remains the main obstacle to reliable yield prediction. Since accurate weather forecasts can be made only a short time in advance, much information can be derived from analyzing past weather data. This paper presents a methodology that addresses the problem of unknown future weather by using a daily mean climatic database, based exclusively on available past measurements. It involves building climate matrix ensembles, combining different time ranges of projected mean climate data and real measured weather data originating from the historical database or from real-time measurements performed in the field. Used as an input for the STICS crop model, the datasets thus computed were used to perform statistical within-season biomass and yield prediction. This work demonstrated that a reliable predictive delay of 3-4 weeks could be obtained. In combination with a local micrometeorological station that monitors climate data in real-time, the approach also enabled us to (i) predict potential yield at the local level, (ii) detect stress occurrence and (iii) quantify yield loss (or gain) drawing on real monitored climatic conditions of the previous few days. [less ▲]

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See detailGene expression pattern of synovial cells from inflammatory and normal areas of osteoarthritis synovial membrane.
Lambert, Cécile ULg; Dubuc, Jean-Emile; Montell, Eulalia et al

in Arthritis and Rheumatism (2014), sous presse

Objective: The aim of this study was to compare the gene expression pattern of synovial cells from inflammatory (I) or normal/reactive (N/R) areas of a synovial membrane harvested from the same ... [more ▼]

Objective: The aim of this study was to compare the gene expression pattern of synovial cells from inflammatory (I) or normal/reactive (N/R) areas of a synovial membrane harvested from the same osteoarthritis (OA) patient. Methods: Synovial tissues were obtained from 12 knee OA patients at the time of total knee replacement. The inflammatory status of the synovial membrane was characterized according to macroscopic criteria and sorted as N/R and I. Biopsies were cultured separately for 7 days. Microarray gene expression profiling between N/R and I areas was performed. Western blot and immunohistochemistry confirmed the identified genes that were differentially expressed. Results: 896 differentially expressed genes between N/R and I zones were identified. The key pathways were related to inflammation, cartilage metabolism, Wnt signaling and angiogenesis. In the inflammatory network, TREM1 and S100A9 were strongly up-regulated. MMP-3 and -9, cathepsin H and S were significantly up-regulated in the cartilage catabolism pathway, whereas the most up-regulated anabolism enzyme was HAS1. Wnt-5A and LRP5 were up-regulated whereas FZD2 and DKK3 were down-regulated in the Wnt signaling. Finally, STC1, a protein involved in angiogenesis was identified as the most up-regulated gene in I zones compared to N/R zones. Conclusion: This study is the first to identify different expression pattern between two areas of the synovial membrane in the same patient. These differences concern several key pathways involved in OA pathogenesis. This analysis also provides information regarding new genes and proteins as potential targets for the future therapeutic. (c) 2013 American College of Rheumatology. [less ▲]

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See detailDrug-Drug Interactions with Sodium-Glucose Cotransporters Type 2 (SGLT2) Inhibitors, New Oral Glucose-Lowering Agents for the Management of Type 2 Diabetes Mellitus.
Scheen, André ULg

in Clinical pharmacokinetics (2014)

Inhibitors of sodium-glucose cotransporters type 2 (SGLT2) reduce hyperglycaemia by decreasing renal glucose threshold and thereby increasing urinary glucose excretion. They are proposed as a novel ... [more ▼]

Inhibitors of sodium-glucose cotransporters type 2 (SGLT2) reduce hyperglycaemia by decreasing renal glucose threshold and thereby increasing urinary glucose excretion. They are proposed as a novel approach for the management of type 2 diabetes mellitus. They have proven their efficacy in reducing glycated haemoglobin, without inducing hypoglycaemia, as monotherapy or in combination with various other glucose-lowering agents, with the add-on value of promoting some weight loss and lowering arterial blood pressure. As they may be used concomitantly with many other drugs, we review the potential drug-drug interactions (DDIs) regarding the three leaders in the class (dapagliglozin, canagliflozin and empagliflozin). Most of the available studies were performed in healthy volunteers and have assessed the pharmacokinetic interferences with a single administration of the SGLT2 inhibitor. The exposure [assessed by peak plasma concentrations (C max) and area under the concentration-time curve (AUC)] to each SGLT2 inhibitor tested was not significantly influenced by the concomitant administration of other glucose-lowering agents or cardiovascular agents commonly used in patients with type 2 diabetes. Reciprocally, these medications did not influence the pharmacokinetic parameters of dapagliflozin, canagliflozin or empagliflozin. Some modest changes were not considered as clinically relevant. However, drugs that could specifically interfere with the metabolic pathways of SGLT2 inhibitors [rifampicin, inhibitors or inducers of uridine diphosphate-glucuronosyltransferase (UGT)] may result in significant changes in the exposure of SGLT2 inhibitors, as shown for dapagliflozin and canagliflozin. Potential DDIs in patients with type 2 diabetes receiving chronic treatment with an SGLT2 inhibitor deserve further attention, especially in individuals treated with several medications or in more fragile patients with hepatic and/or renal impairment. [less ▲]

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See detailSpatial patterns and morphology of termite ( Macrotermes falciger ) mounds in the Upper Katanga, D.R. Congo
Mujinjya, Baile Baziraké; Adam, Marielle; Mees, Florias et al

in Catena (2014), 114

This study examines the spatial distribution patterns and morphological characteristics of Macrotermes falciger mounds in the peri-urban zone of Lubumbashi, D.R. Congo. Spatial patterns of mounds were ... [more ▼]

This study examines the spatial distribution patterns and morphological characteristics of Macrotermes falciger mounds in the peri-urban zone of Lubumbashi, D.R. Congo. Spatial patterns of mounds were assessed using high-resolution satellite images for 24 plots of variable size (3 to 27 ha). Soil morphological features were described for five termite-mound profiles of 5 to 9 m depth/height. A mean areal number density of 2.9 ± 0.4 mounds ha−1 is estimated for the degraded miombo woodland of the study area. Spatial statistical analyses document that termite mounds are regularly distributed in all studied plots. The overall mean nearest-neighbour distance between termite mounds is 44.6 ± 0.6 m. The high relative number of inactive mounds in the region, with regular distribution patterns, suggests that current termite mound occurrences are largely relict features.There are no clear indications for an impact of the nature of the parent material on the spatial distribution of the mounds. One aspect of differences in morphology between the studied mounds is that the stone layer occurs at greater depth in topographic low areas than at crest and slope positions. This is interpreted as being mainlyconditionedbyerosion.Mn–Fe oxideconcentrationsoccurringinallstudiedtermite moundprofiles reflect a seasonally high perched water table beneath the mound, which is more pronounced at lower landscape positions. In summary, mound positions in the habitat are consistent with intraspecific competition rather than soil and substrate characteristics as controlling factor, whereas variation in morphological characteristics between termite-mound profiles appears to be a function of the parent material [less ▲]

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See detailAmphetamine reward in food restricted mice lacking the melanin-concentrating hormone receptor-1
Geuzaine, A; Tyhon, A; Grisar, Thierry ULg et al

in Behavioural Brain Research (2014), 262

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See detailThe Benefits of Errorless Learning for Serial Reaction Time Performance in Alzheimer's Disease.
Schmitz, Xavier ULg; Bier, Nathalie; Joubert, Sven et al

in Journal of Alzheimer's Disease [=JAD] (2014), 39(2), 287-300

Identifying the conditions favoring new procedural skill learning in Alzheimer’s disease (AD) could be important for patients’ autonomy. It has been suggested that error elimination is beneficial during ... [more ▼]

Identifying the conditions favoring new procedural skill learning in Alzheimer’s disease (AD) could be important for patients’ autonomy. It has been suggested that error elimination is beneficial during skill learning, but no study has explored the advantage of this method in sequential learning situations. In this study, we examined the acquisition of a 6-element perceptual-motor sequence by AD patients and healthy older adults (control group). We compared the impact of two preliminary sequence learning conditions (Errorless vs. Errorful) on Serial Reaction Time performance at two different points in the learning process. A significant difference in reaction times for the learned sequence and a new sequence was observed in both conditions in healthy older participants; in AD patients, the difference was significant only in the errorless condition. The learning effect was greater in the errorless than the errorful condition in both groups. However, while the errorless advantage was found at two different times in the learning process in the AD group, in the control group this advantage was observed only at the halfway point. These results support the hypothesis that errorless learning allows for faster automation of a procedure than errorful learning in both AD and healthy older subjects. [less ▲]

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See detailQuoi de neuf en paléontologie du Paléozoïque ?
Blieck, Alain; Crônier, Catherine; Decombeix, Anne-Laure et al

in Géologues (2014), 180

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See detailLa présence isiaque dans le Péloponnèse. Sur les traces des lieux de culte
Veymiers, Richard ULg

in Revue archéologique. Bulletin de la Société française d'archéologie classique (SFAC). (2014), 1

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See detailComparative study of alkaline extraction process of hemicelluloses from pear pomace
Rabetafika, Holy-Nadia ULg; Bchir, Brahim ULg; Blecker, Christophe ULg et al

in Biomass & Bioenergy (2014), 61

Hemicelluloses were produced from pear pomace using direct alkaline extraction (sodium hydroxide and hydrogen peroxide) and two-step extraction with delignification pre-treatment (acidified sodium ... [more ▼]

Hemicelluloses were produced from pear pomace using direct alkaline extraction (sodium hydroxide and hydrogen peroxide) and two-step extraction with delignification pre-treatment (acidified sodium chlorite/sodium hydroxide). The aim of the study was to compare the extraction yield, composition and physicochemical characteristics of isolated hemicelluloses by size exclusion chromatography, FTIR and thermogravimetric analyses. Solid residues were analysed in order to evaluate the effect of processes on co-products (lignins and cellulose). Delignification of material (up to 995.4 g kg−1 of original lignins) during the direct alkaline hydrogen peroxide and two-step acidified sodium chlorite/sodium hydroxide processes improved the hemicellulose extraction yield attaining up to 945.3 g kg−1. Hemicelluloses were mainly composed of xylans (xylose/glucose ratio of 4.6–16.2) and had low lignin content (53.5–61.0 g kg−1 dry matter). Those from direct sodium hydroxide extraction were composed of xylans and glucans (xylose/glucose ratio of 1.5) with high content of lignins (149.3 g kg−1 dry matter). All isolated fractions were a mixture of polymers and oligomers with a molecular mass ranging from 1710 g mol−1 to 8 870 000 g mol−1. The two-step process gave the most pure cellulose residue (799.2 g kg−1 dry matter). According to results, the direct alkaline extraction with hydrogen peroxide was a promising process for the production of pure xylose-rich hemicelluloses from pear pomace solubilizing 802.2 g kg−1 of the original hemicelluloses but induced fragmentation of hemicelluloses. [less ▲]

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See detailSarapis et Neôtera élus parmi les dieux
Veymiers, Richard ULg

in Revue Archéologique (2014), (1), 37-56

One of the bronze plates formerly in the Bianchini collection, which entered the Cabinet des Médailles (Paris) at the end of the 18th century, bears a text and an image, supposedly unintelligible and ... [more ▼]

One of the bronze plates formerly in the Bianchini collection, which entered the Cabinet des Médailles (Paris) at the end of the 18th century, bears a text and an image, supposedly unintelligible and therefore thought to be of a magic nature. A new examination of this artefact, actually the main part of a bracelet, shows that it depicts an assembly of twenty-eight divinities, illustrating the religious landscape of Egypt in the 2nd-3rd century, and that it is inscribed with two short acclamations. The first one exalts the greatness of the name of Sarapis, the second that of Neôtera the invincible. The identity of this goddess is difficult to define, but she often seems to correspond to a form of Isis assimilated to Korè. The glorifying invocation of these two gods, depicted with their pantheon, may be considered to be an expression of what is today called “megatheism”. [less ▲]

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See detailBrains creating stories of selves: the neural basis of autobiographical reasoning.
D'Argembeau, Arnaud ULg; Cassol, Helena; Phillips, Christophe ULg et al

in Social Cognitive and Affective Neuroscience (2014), 9

Personal identity critically depends on the creation of stories about the self and one's life. The present study investigates the neural substrates of autobiographical reasoning, a process central to the ... [more ▼]

Personal identity critically depends on the creation of stories about the self and one's life. The present study investigates the neural substrates of autobiographical reasoning, a process central to the construction of such narratives. During fMRI scanning, participants approached a set of personally significant memories in two different ways: on some trials, they remembered the concrete content of the events (autobiographical remembering), whereas on other trials they reflected on the broader meaning and implications of their memories (autobiographical reasoning). Relative to remembering, autobiographical reasoning recruited a left-lateralized network involved in conceptual processing (including the dorsal medial prefrontal cortex (MPFC), inferior frontal gyrus, middle temporal gyrus, and angular gyrus). The ventral MPFC-an area that may function to generate personal/affective meaning-was not consistently engaged during autobiographical reasoning across participants but, interestingly, the activity of this region was modulated by individual differences in interest and willingness to engage in self-reflection. These findings support the notion that autobiographical reasoning and the construction of personal narratives go beyond mere remembering in that they require deriving meaning and value from past experiences. [less ▲]

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See detailReprint of: Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich, et al.
Gore, A. C.; Balthazart, Jacques ULg; Bikle, D. et al

in Frontiers in neuroendocrinology (2014), 35(1), 2-5

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See detailCould the chemical contamination be the cause of the increase in the number of stranded harbour porpoises (Phocoena phocoena) along the Southern North Sea?
Mahfouz, C.; Henry, F.; Pezeril, S. et al

in Environmental Research (2014)

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See detailInflorescence development in tomato: gene functions within a zigzag model.
Périlleux, Claire ULg; Lobet, Guillaume ULg; Tocquin, Pierre ULg

in Frontiers in Plant Science (2014), 5

Tomato is a major crop plant and several mutants have been selected for breeding but also for isolating important genes that regulate flowering and sympodial growth. Besides, current research in ... [more ▼]

Tomato is a major crop plant and several mutants have been selected for breeding but also for isolating important genes that regulate flowering and sympodial growth. Besides, current research in developmental biology aims at revealing mechanisms that account for diversity in inflorescence architectures. We therefore found timely to review the current knowledge of the genetic control of flowering in tomato and to integrate the emerging network into modeling attempts. We developped a kinetic model of the tomato inflorescence development where each meristem was represented by its ‘vegetativeness’ (V), reflecting its maturation state towards flower initiation. The model followed simple rules: maturation proceeded continuously at the same rate in every meristem (dV); floral transition and floral commitment occurred at threshold levels of V; lateral meristems were initiated with a gain of V (ΔV) relative to the V level of the meristem from which they derived. This last rule created a link between successive meristems and gave to the model its zigzag shape. We next exploited the model to explore the diversity of morphotypes that could be generated by varying dV and ΔV and matched them with existing mutant phenotypes. This approach, focused on the development of the primary inflorescence, allowed us to elaborate on the genetic regulation of the kinetic model of inflorescence development. We propose that the lateral inflorescence meristem fate in tomato is closer to an immature flower meristem than to the inflorescence meristem of Arabidopsis. In the last part of our paper, we extend our thought to spatial regulators that should be integrated in a next step for unraveling the relationships between the different meristems that participate to sympodial growth. [less ▲]

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See detailA combinatorial branch-and-bound algorithm for box search
Mathieu, Sébastien ULg; Louveaux, Quentin ULg

in Discrete Optimization (2014), 13

Considering a set of points in a multi-dimensional space with an associated real value for each point, we want to find the box with the maximum sum of the values of the included points. This problem has ... [more ▼]

Considering a set of points in a multi-dimensional space with an associated real value for each point, we want to find the box with the maximum sum of the values of the included points. This problem has applications in data mining and can be formulated as a mixed-integer linear program. We propose a branch-and-bound algorithm where the bounding is obtained by combinatorial arguments instead of the traditional linear relaxation. Computational experiments show that this approach competes with current state of the art mixed-integer solvers. The algorithm proposed in this paper may be seen as a simple and dependence-free method to solve the box search problem. [less ▲]

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See detailN-heterocyclic carbene catalyzed carba-, sulfa-, and phospha-Michael additions with NHC·CO2 adducts as precatalysts
Hans, Morgan ULg; Delaude, Lionel ULg; Rodriguez, Jean et al

in Journal of Organic Chemistry (2014), 79(6), 2758-2764

N-heterocyclic carbene catalyzed Michael additions have been revisited with 1,3-dialkyl- or 1,3-diarylimidazol(in)ium-2-carboxylates, that is, NHC·CO2 adducts, as the source of the free NHC catalysts in ... [more ▼]

N-heterocyclic carbene catalyzed Michael additions have been revisited with 1,3-dialkyl- or 1,3-diarylimidazol(in)ium-2-carboxylates, that is, NHC·CO2 adducts, as the source of the free NHC catalysts in solution. Using these precatalysts, a number of efficient carba-, sulfa-, and phospha-Michael additions were achieved very conveniently, without the need for an external strong base to generate the NHC by deprotonation of an azolium salt. To further expand the scope of the procedure, some NHC-catalyzed sulfa-Michael/aldol organocascades were also investigated. [less ▲]

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See detailAging Reduces the Stimulating Effect of Blue Light on Cognitive Brain Functions
Daneault, Véronique; Hébert, Marc; Albouy, Geneviève et al

in Sleep (2014)

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See detailDetection of Usutu virus in a bullfinch (Pyrrhula pyrrhula) and a great spotted woodpecker (Dendrocopos major) in north-west Europe
Garigliany, Mutien-Marie ULg; Marlier, Didier ULg; Tenner-Racz, Klara et al

in Veterinary Journal (2014), 199

In October 2012, a 3-year-old bullfinch (Pyrrhula pyrrhula) held in captivity for its entire lifespan and a wild adult great spotted woodpecker (Dendrocopos major), both with neurological signs, were ... [more ▼]

In October 2012, a 3-year-old bullfinch (Pyrrhula pyrrhula) held in captivity for its entire lifespan and a wild adult great spotted woodpecker (Dendrocopos major), both with neurological signs, were found 4 km from each other and 5 days apart in the Meuse Valley, Belgium. Non-suppurative encephalitis and mild degeneration and necrosis were identified in the brain and cerebellum, and Usutu virus antigen and RNA were detected by immunohistochemistry and real-time reverse transcriptase PCR, respectively. The two cases reported here represent the most western distribution of clinical disease in birds due to Usutu virus. [less ▲]

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See detailLa Cour d'appel de Paris saisit l'Autorité de la Concurrence d'une demande d'avis pour apprécier le caractère prédateur d'un prix nul.
Sibony, Anne-Lise ULg

in Concurrences : Revue des Droits de la Concurrence (2014), 1

GCUE, 16.10.13, Vivendi v. Commission, case T-432/10 The General Court of the European Union states that the Commission enjoys a wide margin of discretion when taking into account decisions and documents ... [more ▼]

GCUE, 16.10.13, Vivendi v. Commission, case T-432/10 The General Court of the European Union states that the Commission enjoys a wide margin of discretion when taking into account decisions and documents established by national regulators. [less ▲]

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See detailProcedural learning across modalities in French-speaking children with specific language impairment
Gabriel, Audrey ULg; Meulemans, Thierry ULg; Parisse, Christophe et al

in Applied Psycholinguistics (2014)

It has been suggested that the language problems encountered in specific language impairment (SLI) arise from basal ganglia abnormalities that lead to impaired procedural memory. However, recent serial ... [more ▼]

It has been suggested that the language problems encountered in specific language impairment (SLI) arise from basal ganglia abnormalities that lead to impaired procedural memory. However, recent serial reaction time (SRT) studies did not reveal any differences between the SLI and typically developing (TD) groups on the measures of procedural memory linked to visual sequence learning. In this paper, 16 children with and without SLI were compared on two versions of SRT tasks: a visual task and an auditory one. The results showed that children with SLI were as fast as their TD peers in both modalities. All of the children obtained similar specific sequence learning indices, indicating that they were able to detect regularities in both modalities. Although children with SLI were as accurate as their TD peers for the visual SRT task, they made more errors than their TD peers in auditory SRT conditions. The results indicate that, in relation to procedural memory, the core of the impairment in SLI is not linked to difficulties in the detection of regularities. We argue that when children with SLI present some difficulties, the children’s weaknesses might depend on the type of processing involved (e.g., tasks involving auditory sequences). [less ▲]

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See detailThe impact of lexical frequency on sentence comprehension in children with specific language impairment
Leclercq, Anne-Lise ULg; Majerus, Steve ULg; Jacob, Laura et al

in Research in Developmental Disabilities (2014), 35

Children with SLI generally exhibit poor sentence comprehension skills. We examined the specific impact of grammatical complexity and lexical frequency on comprehension performance, yielding contrasting ... [more ▼]

Children with SLI generally exhibit poor sentence comprehension skills. We examined the specific impact of grammatical complexity and lexical frequency on comprehension performance, yielding contrasting results. The present study sheds new light on sentence comprehension in children with SLI by investigating a linguistic factor which has attracted little research interest: the impact of the lexical frequency of known words on sentence comprehension. We also examined the impact of grammatical complexity and sentence length by independently varying these two factors. Fifteen children with SLI, 15 age- and IQ-matched controls, and 15 controls matched on lexical and grammatical skills, performed sentence comprehension tasks in which three linguistic factors were manipulated: lexical frequency (sentences containing words of either low or high lexical frequency), grammatical complexity (sentence containing either a subject relative clause or an object relative clause) and sentence length (either short or long sentences). Results indicated that children with SLI performed more poorly overall compared to age- and IQmatched children and to lexical and morphosyntactic age-matched children. However, their performance was not more affected by either sentence length or clause type than that of control children. Only lexical frequency affected sentence comprehension to a greater extent in children with SLI relative to the control groups, revealing that SLI children’s sentence comprehension abilities are particularly affected by the presence of lowfrequency but familiar words. [less ▲]

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See detailThe Threshold Photoelectron Spectrum of Geminal Chloro-Fluoro-ethene (1,1-C2H2FCl) isomer. Experiment and Theory.
Locht, Robert ULg; Dehareng, Dominique ULg; Leyh, Bernard ULg

in Journal of Physics : B Atomic Molecular & Optical Physics (2014), 47(8), 0851019

The threshold photoelectron spectrum (TPES) of 1,1-C2H2FCl has been measured for the first time using synchrotron radiation. It has been compared to the HeI photoelectron spectrum (PES) obtained earlier ... [more ▼]

The threshold photoelectron spectrum (TPES) of 1,1-C2H2FCl has been measured for the first time using synchrotron radiation. It has been compared to the HeI photoelectron spectrum (PES) obtained earlier [Tornow G. et al., Chem.Phys. 146 115 (1990)]. Eight photoelectron bands have been observed at 10.22 eV, 12.45 eV, 13.28 eV, 14.29 eV, 14.99 eV, 17.12 eV, 17.67 eV, and at 20.23 eV successively. Only the first three bands exhibit a rich and extensive vibrational structure. Their adiabatic ionization energies are measured and a detailed vibrational analysis is presented. The assignments of the electronic bands and of the vibrational wavenumbers were made by using ab initio quantum chemical calculations. These allowed us to provide the MO description of the eight electronic states in terms of ionization and double excitation. The good correlation between predicted vibrational wavenumbers and the experimental values provides a strong basis for the assignment of all the vibrational structures. [less ▲]

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See detailInventaire préliminaire des termites (Isoptera) du plateau des Batékés en République Démocratique du Congo
Kifukieto, Carmel; Deligne, Jean; Kachaka, Claude et al

in Entomologie Faunistique = Faunistic Entomology (2014), 67

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See detailActeurs, ressources et réseaux sociologiques d'échanges à partir de l'expérience belge
Vrancken, Didier ULg

in Sociologies Pratiques (2014)

Plutôt que de procéder à un bilan de la sociologie en Belgique francophone, l'auteur opte pour une présentation de cette dernière à partir de quelques travaux qui se sont attelés à décrypter les ... [more ▼]

Plutôt que de procéder à un bilan de la sociologie en Belgique francophone, l'auteur opte pour une présentation de cette dernière à partir de quelques travaux qui se sont attelés à décrypter les arrangements, les compromis, les accords au sein d'un pays continuellement confronté à ces mêmes questions. [less ▲]

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See detailA New Look at Ichthyosaur Long Bone Microanatomy and Histology: Implications for Their Adaptation to an Aquatic Life
Houssaye, Alexandra; Scheyer, Torsten; Kolb, Christian et al

in PLoS ONE (2014), 9(4), 95637

Background Ichthyosaurs are Mesozoic reptiles considered as active swimmers highly adapted to a fully open-marine life. They display a wide range of morphologies illustrating diverse ecological grades ... [more ▼]

Background Ichthyosaurs are Mesozoic reptiles considered as active swimmers highly adapted to a fully open-marine life. They display a wide range of morphologies illustrating diverse ecological grades. Data concerning their bone microanatomical and histological features are rather limited and suggest that ichthyosaurs display a spongious, “osteoporotic-like” bone inner structure, like extant cetaceans. However, some taxa exhibit peculiar features, suggesting that the analysis of the microanatomical and histological characteristics of various ichthyosaur long bones should match the anatomical diversity and provide information about their diverse locomotor abilities and physiology. Methodology/Principal Findings The material analyzed for this study essentially consists of mid-diaphyseal transverse sections from stylopod bones of various ichthyosaurs and of a few microtomographic (both conventional and synchrotron) data. The present contribution discusses the histological and microanatomical variation observed within ichthyosaurs and the peculiarities of some taxa (Mixosaurus, Pessopteryx). Four microanatomical types are described. If Mixosaurus sections differ from those of the other taxa analyzed, the other microanatomical types, characterized by the relative proportion of compact and loose spongiosa of periosteal and endochondral origin respectively, seem to rather especially illustrate variation along the diaphysis in taxa with similar microanatomical features. Our analysis also reveals that primary bone in all the ichthyosaur taxa sampled (to the possible exception of Mixosaurus) is spongy in origin, that cyclical growth is a common pattern among ichthyosaurs, and confirms the previous assumptions of high growth rates in ichthyosaurs. Conclusions/Significance The occurrence of two types of remodelling patterns along the diaphysis, characterized by bone mass decrease and increase respectively is described for the first time. It raises questions about the definition of the osseous microanatomical specializations bone mass increase and osteoporosis, notably based on the processes involved, and reveals the difficulty in determining the true occurrence of these osseous specializations in ichthyosaurs. [less ▲]

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See detailEffect of polyamines or precursors on the hyperhydricity process in micropropagated apple trees.
Tabart; Franck, Thierry ULg; Kevers, Claire ULg et al

in Plant Cell, Tissue & Organ Culture (2014)

Hyperhydricity is a physiological disorder affecting tissue-culture-generated plants. It is associated with excessive hydration and poor lignification. The effects of exogenous polyamines (spermidine and ... [more ▼]

Hyperhydricity is a physiological disorder affecting tissue-culture-generated plants. It is associated with excessive hydration and poor lignification. The effects of exogenous polyamines (spermidine and putrescine) and polyamine precursors (arginine and ornithine) were studied on ‘Jonagold’ apple shoots subjected to hyperhydric conditions for one in vitro multiplication cycle (28 days) on a culture medium containing gelrite as gelling agent. Supplementation of the gelrite-containing medium with 10-5 M spermidine, ornithine, or arginine reduced the percentage of hyperhydricity by at least 50%. Exogenous supplementation with spermidine or a polyamine precursor also caused total phenolics and the antioxidant capacity (measured by ORAC and DPPH assays) to decrease in shoots during the first two weeks. These results suggest an important role of spermidine and its precursor ornithine in countering hyperhydricity. Supplementation could help to maintain high endogenous levels of polyamines and phenolamides necessary for cell osmoregulation, antioxidant protection, cell wall cross-linking, and plant growth regulation. [less ▲]

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See detailHair Mercury and urinary cadmium levels in Belgian children and their mothers within the framework of the COPHES/DEMOCOPHES projects
PIRARD, Catherine ULg; Koppen, Gudrun; De Cremer, Koen et al

in Science of the Total Environment (2014), 472

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See detailMechanism of the medium-duration afterhyperpolarization in rat serotonergic neurons
Alix, Philippe ULg; Venkatesan, Kumar; Scuvée-Moreau, Jacqueline et al

in European Journal of Neuroscience (2014), 39(2), 186-196

Most serotonergic neurons display a prominent medium-duration afterhyperpolarization (mAHP), which is mediated by small conductance Ca2+-activated K+ (SK) channels. Recent ex vivo and in vivo experiments ... [more ▼]

Most serotonergic neurons display a prominent medium-duration afterhyperpolarization (mAHP), which is mediated by small conductance Ca2+-activated K+ (SK) channels. Recent ex vivo and in vivo experiments have suggested that SK channel blockade increases the firing rate and/or bursting in these neurons. The purpose of this study was therefore to characterize the source of Ca2+ which activates the mAHP channels in serotonergic neurons. In voltage clamp experiments, an outward current was recorded at -60 mV after a depolarizing pulse to + 100 mV. A supra-maximal concentration of the SK channel blockers apamin or (-)- bicuculline methiodide blocked this outward current. This current was also sensitive to the broad Ca2+ channel blocker Co2+ and was partially blocked by both ω-conotoxin and mibefradil, which are blockers of N-type and T-type Ca2+ channels, respectively. Neither blockers of other voltage-gated Ca2+ channels nor DBHQ, an inhibitor of Ca2+-induced Ca2+ release, had any effect on the SK current. [less ▲]

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See detailcompte rendu de : Maria Chiara SCAPPATICCIO, Accentus, distinctio, apex. L’accentazione grafica tra Grammatici Latini e papiri virgiliani
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2014)

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See detailContrasting patterns of phytoplankton communities in two coastal ecosystems in relation to environmental factors (Corsica, NW Mediterranean Sea)
Garrido, Marie; Koeck, Barbara; Goffart, Anne ULg et al

in Diversity (2014), 6

Corsica Island is a sub-basin of the Northwestern Mediterranean Sea, with hydrological features typical of both oligotrophic systems and eutrophic coastal zones. Phytoplankton assemblages in two coastal ... [more ▼]

Corsica Island is a sub-basin of the Northwestern Mediterranean Sea, with hydrological features typical of both oligotrophic systems and eutrophic coastal zones. Phytoplankton assemblages in two coastal ecosystems of Corsica (the deep Bay of Calvi and the shallow littoral of Bastia) show contrasting patterns over a one-year cycle. In order to determine what drives these variations, seasonal changes in littoral phytoplankton are considered together with environmental parameters. Our methodology combined a survey of the physico-chemical structure of the subsurface water with a characterization of the phytoplankton community structure. Sampling provided a detailed record of the seasonal changes and successions that occur in these two areas. Results showed that the two sampled stations presented different phytoplankton abundance and distribution patterns, notably during the winter–spring bloom period. Successions in pico-, nano-, and microphytoplankton communities appeared mainly driven by differences in the ability to acquire nutrients, and in community-specific growth rates. Phytoplankton structure and dynamics are discussed in relation to available data on the Northwestern Mediterranean Sea. These results confirm that integrated monitoring of coastal areas is a requisite for gaining a proper understanding of marine ecosystems. [less ▲]

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See detailA one phase thermomechanical model for the numerical simulation of semi-solid material behavior. Application to thixoforming
Koeune, Roxane; Ponthot, Jean-Philippe ULg

in International Journal of Plasticity (2014), 58

This work deals with the development of an appropriate constitutive model for semi-solid thixoforming processes of metallic alloys. These processes rely on a very specific material behavior called ... [more ▼]

This work deals with the development of an appropriate constitutive model for semi-solid thixoforming processes of metallic alloys. These processes rely on a very specific material behavior called thixotropy that can be displayed by some metallic alloys heated up to their semi-solid state. It is a particular evolutionary behavior which is characterized by a solidlike behavior at rest and a liquid flow during shearing, thus by a decrease of the viscosity and of the resistance to deformation while sheared. An original one-phase thermo-elasto-viscoplastic constitutive model has been developed. The basic idea is to extend the classical isotropic hardening and viscosity models beyond the solid state by considering two more non-dimensional internal scalar parameters. The semi-solid state is treated as a particular case, and one of the main features of the proposed constitutive model is that it remains valid over a wide range of temperatures, starting from room temperature to above the liquidus in a continuous manner, thus allowing a continuous transition between classical solid and fluid behavior. Another feature is that, after the forming step, it is possible to simulate the cooling down of the component back to room temperature using the elastic–viscoplastic model. So it is possible to estimate residual stresses, something that is definitely impossible while using a fluid-like model or a rigid viscoplastic approach. The presented model is illustrated and validated by means of representative numerical applications, as two different extrusion tests are carried out and the computed predictions are compared to experimental results. [less ▲]

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See detailRemarkably low genetic diversity and strong population structure in common bottlenose dolphins (Tursiops truncatus) from coastal waters of the Southwestern Atlantic Ocean
Fruet, Pedro; Secchi, Eduardo; Daura-Jorge, Fabio et al

in Conservation Genetics (2014)

Knowledge about the ecology of bottlenose dolphins in the Southwestern Atlantic Ocean is scarce. Increased by-catch rates over the last decade in coastal waters of southern Brazil have raised concerns ... [more ▼]

Knowledge about the ecology of bottlenose dolphins in the Southwestern Atlantic Ocean is scarce. Increased by-catch rates over the last decade in coastal waters of southern Brazil have raised concerns about the decline in abundance of local dolphin communities. Lack of relevant data, including information on population structure and connectivity, have hampered an assessment of the conservation status of bottlenose dolphin communities in this region. Here we combined analyses of 16 microsatellite loci and mitochondrial DNA (mtDNA) control region sequences to investigate genetic diversity, structure and connectivity in 124 biopsy samples collected over six communities of photographically identified coastal bottlenose dolphins in southern Brazil, Uruguay and central Argentina. Levels of nuclear genetic diversity were remarkably low (mean values of allelic diversity and heterozygosity across all loci were 3.6 and 0.21, respectively), a result that possibly reflects the small size of local dolphin communities. On a broad geographical scale, strong and significant genetic differentiation was found between bottlenose dolphins from southern Brazil-Uruguay (SB-U) and Baia San Antonio (BSA), Argentina (AMOVA mtDNA ΦST = 0.43; nuclear FST = 0.46), with negligible contemporary gene flow detected based on Bayesian estimates. On a finer scale, moderate but significant differentiation (AMOVA mtDNA ΦST = 0.29; nuclear FST = 0.13) and asymmetric gene flow was detected between five neighbouring communities in SB-U. Based on the results we propose that BSA and SB-U represent two distinct Evolutionarily Significant Units (ESUs), and that communities from SB-U comprise five distinct Management Units (MUs). Under this scenario, conservation efforts should prioritize the areas in Southern Brazil where dolphins from three MUs overlap in their home ranges and where by-catch rates are reportedly higher. [less ▲]

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See detailDe la nullité des décisions de l’assemblée générale des sociétés coopératives
Léonard, Laura ULg; Caprasse, Olivier ULg

in Le droit des affaires = Het ondernemingsrecht (2014), 109

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See detailExtremely Organic-rich Coma of Comet C/2010 G2 (Hill) during its Outburst in 201
Kawakita, H; Dello Russo; Vervack, R et al

in The Astrophysical Journal (2014)

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See detailThree species for the price of one within the moss Homalothecium sericeum s.l.
Hedenäs, Lars; Desamore, Aurélie ULg; Laenen, Benjamin ULg et al

in Taxon (2014), 63

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See detailClick-Evoked Otoacoustic Emissions in Children and Adolescents with Gender Identity Disorder.
Burke, Sarah M.; Menks, Willeke M.; Cohen-Kettenis, Peggy T. et al

in Archives of sexual behavior (2014)

Click-evoked otoacoustic emissions (CEOAEs) are echo-like sounds that are produced by the inner ear in response to click-stimuli. CEOAEs generally have a higher amplitude in women compared to men and ... [more ▼]

Click-evoked otoacoustic emissions (CEOAEs) are echo-like sounds that are produced by the inner ear in response to click-stimuli. CEOAEs generally have a higher amplitude in women compared to men and neonates already show a similar sex difference in CEOAEs. Weaker responses in males are proposed to originate from elevated levels of testosterone during perinatal sexual differentiation. Therefore, CEOAEs may be used as a retrospective indicator of someone's perinatal androgen environment. Individuals diagnosed with Gender Identity Disorder (GID), according to DSM-IV-TR, are characterized by a strong identification with the other gender and discomfort about their natal sex. Although the etiology of GID is far from established, it is hypothesized that atypical levels of sex steroids during a critical period of sexual differentiation of the brain might play a role. In the present study, we compared CEOAEs in treatment-naive children and adolescents with early-onset GID (24 natal boys, 23 natal girls) and control subjects (65 boys, 62 girls). We replicated the sex difference in CEOAE response amplitude in the control group. This sex difference, however, was not present in the GID groups. Boys with GID showed stronger, more female-typical CEOAEs whereas girls with GID did not differ in emission strength compared to control girls. Based on the assumption that CEOAE amplitude can be seen as an index of relative androgen exposure, our results provide some evidence for the idea that boys with GID may have been exposed to lower amounts of androgen during early development in comparison to control boys. [less ▲]

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See detailThe assessment of job satisfaction for the Healthcare providers in University Clinics of Lubumbashi, D.R.Congo
Mundongo Tshamba, Henri; Van Caillie, Didier ULg; Kaj Malonga, Françoise et al

in Panafrican Medical Journal (2014), 2014

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See detailMorpho-histology and genotype dependence of in vitro morphogenesis in mature embryo cultures of wheat.
Delporte, Fabienne; Pretova, Anna; du Jardin, Patrick ULg et al

in Protoplasma (2014)

Cellular totipotency is one of the basic principles of plant biotechnology. Currently, the success of the procedure used to produce transgenic plants is directly proportional to the successful insertion ... [more ▼]

Cellular totipotency is one of the basic principles of plant biotechnology. Currently, the success of the procedure used to produce transgenic plants is directly proportional to the successful insertion of foreign DNA into the genome of suitable target tissue/cells that are able to regenerate plants. The mature embryo (ME) is increasingly recognized as a valuable explant for developing regenerable cell lines in wheat biotechnology. We have previously developed a regeneration procedure based on fragmented ME in vitro culture. Before we can use this regeneration system as a model for molecular studies of the morphogenic pathway induced in vitro and investigate the functional links between regenerative capacity and transformation receptiveness, some questions need to be answered. Plant regeneration from cultured tissues is genetically controlled. Factors such as age/degree of differentiation and physiological conditions affect the response of explants to culture conditions. Plant regeneration in culture can be achieved through embryogenesis or organogenesis. In this paper, the suitability of ME tissues for tissue culture and the chronological series of morphological data observed at the macroscopic level are documented. Genetic variability at each step of the regeneration process was evaluated through a varietal comparison of several elite wheat cultivars. A detailed histological analysis of the chronological sequence of morphological events during ontogeny was conducted. Compared with cultures of immature zygotic embryos, we found that the embryogenic pathway occurs slightly earlier and is of a different origin in our model. Cytological, physiological, and some biochemical aspects of somatic embryo formation in wheat ME culture are discussed. [less ▲]

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See detailAntithymocyte globulin before allogeneic stem cell transplantation for progressive myelodysplastic syndrome : a study from the French Society of Bone Marrow Transplantation and Cellular Therapy
Duléry, Rémy; Mohty, Mohamad; Duhamel, Alain et al

in Biology of Blood & Marrow Transplantation (2014), 20

We investigated the impact of rabbit antithymocyte globulins (ATG) on patient outcomes after allogeneic stem cell transplantation (allo-SCT) for progressive myelodysplastic syndrome (MDS). Of the 242 ... [more ▼]

We investigated the impact of rabbit antithymocyte globulins (ATG) on patient outcomes after allogeneic stem cell transplantation (allo-SCT) for progressive myelodysplastic syndrome (MDS). Of the 242 consecutive patients who underwent allo-SCT for progressive MDS between October 1999 and December 2009, 93 received ATG (ATG group) at the median dose of 5 mg/kg, whereas 149 patients did not (no-ATG group). Donors were sibling (n ¼ 153) or HLA-matched unrelated (n ¼ 89). Patients received blood (n ¼ 90) or marrow (n ¼ 152) grafts after either myeloablative (n ¼ 109) or reduced-intensity (n ¼ 133) conditioning. Three-year overall and event-free survival, nonrelapse mortality, relapse, and chronic graft-versus-host disease (GVHD) development were not significantly different between the 2 groups. In contrast, acute grade II to IV GVHD occurred more often in the no-ATG group (55% of the patients) than in the ATG group (27%, P < .0001). Similar results were observed with acute grade III to IV GVHD (28% and 14% in the no-ATG group and ATG group, respectively; P ¼ .009). In multivariate analysis, after adjustment with propensity score, the absence of ATG was the strongest parameter associated with an increased risk of acute grade II to IV GVHD (hazard ratio, 2.13; 95% confidence interval, 1.35 to 3.37; P ¼.001]. ATG had no impact on overall and event-free survival or cumulative incidence of the relapse. In conclusion, the addition of ATG to allo-SCT conditioning did not increase the incidence of relapse of patients with progressive MDS. The incidence of acute GVHD was decreased without compromising outcomes. [less ▲]

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See detailUn projet européen de recherche interventionnelle, pour quelle santé mentale ?
Fond-Harmant, Laurence; Absil, Gaëtan ULg

in Priorités Santé (2014), (39), 18-19

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See detailNumerical study of shear band instability and effect of cavitation on the response of a specimen under undrained biaxial loading
Sieffert, Yannick; Buzzi, Olivier; Collin, Frédéric ULg

in International Journal of Solids and Structures (2014), 51(9), 16861696

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See detailCrédits aux PME et clause de résiliation unilatérale au profit de la banque
Biquet, Christine ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2014), (5), 219-220

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See detailAccuracy of asymptotic standard errors of the maximum and weighted likelihood estimators of proficiency levels with short tests
Magis, David ULg

in Applied Psychological Measurement (2014), 38

The maximum likelihood (ML) and the weighted likelihood (WL) estimators are commonly used to obtain proficiency level estimates with pre-calibrated item parameters. Both estimators have the same ... [more ▼]

The maximum likelihood (ML) and the weighted likelihood (WL) estimators are commonly used to obtain proficiency level estimates with pre-calibrated item parameters. Both estimators have the same asymptotic standard error (ASE) that can be easily derived from the expected information function of the test. However, the accuracy of this asymptotic formula is uncertain with short tests when only a few items are administered. The purpose of this paper is to compare the ASE of these estimators to their exact values, evaluated at the proficiency level estimates. The exact SE is computed by generating the full exact sample distribution of the estimators, so its practical feasibility is limited to small tests (except under the Rasch model). A simulation study was conducted to compare the ASE and the exact SE of the ML and WL estimators, to the “true” SE (i.e., computed as the exact SE with the true proficiency levels). It is concluded that with small tests, the exact SEs are less biased and return smaller root mean squared error values than the asymptotic SEs, while as expected the two estimators return similar results with longer tests. [less ▲]

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See detailSarcopénie. Quoi de neuf en 2014 ?
Beaudart, Charlotte ULg; GILLAIN, Sophie ULg; Petermans, Jean ULg et al

in Revue Médicale de Liège (2014), 69(5-6), 251-257

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