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See detailComparison of emergence times and quality between isoflurane and sevoflurane in rhesus macaque (Macaca mulatta) undergoing neurosurgical procedure
Bertrand, Henri ULg; Springer, Svenja; Burnside, Wesley et al

in Laboratory Animals (2017)

Volatile agents for anaesthesia are widely used for anaesthetizing laboratory primates, and isoflurane is one of the most frequently used agents. Sevoflurane has been shown to offer a more rapid recovery ... [more ▼]

Volatile agents for anaesthesia are widely used for anaesthetizing laboratory primates, and isoflurane is one of the most frequently used agents. Sevoflurane has been shown to offer a more rapid recovery than iso- flurane in a number of species, but no comparisons have been made in non-human primates. This study compared the recovery characteristics of isoflurane and sevoflurane in rhesus macaques undergoing experi- mental neurosurgery. Twelve primates (7 males and 5 females) were randomly allocated to the treatment groups. They were sedated with ketamine (10 mg/kg) and anaesthesia was induced with propofol (usually 8 mg/kg intravenously [IV]). Anaesthesia was maintained with either sevoflurane (SEVO) (2.2 0.4%) or iso- flurane (ISO) (1.2 0.2%) and alfentanil (0.2–0.5 mg/kg/min IV) for 332–592 min. Animals were mechanically ventilated. Meloxicam (0.3mg/kg) and methylprednisolone infusion (5.4mg/kg/h) were also administered. Time to extubation after cessation of anaesthesia was significantly shorter with sevoflurane (ISO: 7.0 1.8 min; SEVO: 3.6 1.5; *P 1⁄4 0.005) as was the time to the animal sitting unaided (ISO: 15.7 8.2 min; SEVO: 7.1 1.7min; *P1⁄40.004). No significant difference in the quality of recovery following isoflurane or sevoflurane anaesthesia was found. In conclusion, isoflurane and sevoflurane are both suitable volatile agents for the maintenance of general anaesthesia in rhesus macaques undergoing experimental neurosur- gical procedures. The two volatile agents presented a similar emergence quality profile, however sevoflurane anaesthesia was associated with a faster recovery, offering the possibility of conducting earlier post-operative neurological assessment. [less ▲]

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See detailComparison of clinical effects of epidural levobupivacaine morphine versus bupivacaine morphine in dogs undergoing elective pelvic limb surgery
Cerasoli, Ilaria; Tutunaru, Alexandru-Cosmin ULg; Cenani, Alessia et al

in Veterinary Anaesthesia & Analgesia (2017)

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See detailIn Memoriam Léon Lacroix (1909-2016)
Rochette, Bruno ULg

in Antiquité Classique (2017), 86

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See detailModeling pre-metastatic lymphvascular niche in the mouse ear sponge assay.
Garcia-Caballero, Melissa; Van De Velde, Maureen ULg; Blacher, Silvia ULg et al

in Scientific Reports (2017), 7

Lymphangiogenesis, the formation of new lymphatic vessels, occurs in primary tumors and in draining lymph nodes leading to pre-metastatic niche formation. Reliable in vivo models are becoming instrumental ... [more ▼]

Lymphangiogenesis, the formation of new lymphatic vessels, occurs in primary tumors and in draining lymph nodes leading to pre-metastatic niche formation. Reliable in vivo models are becoming instrumental for investigating alterations occurring in lymph nodes before tumor cell arrival. In this study, we demonstrate that B16F10 melanoma cell encapsulation in a biomaterial, and implantation in the mouse ear, prevents their rapid lymphatic spread observed when cells are directly injected in the ear. Vascular remodeling in lymph nodes was detected two weeks after sponge implantation, while their colonization by tumor cells occurred two weeks later. In this model, a huge lymphangiogenic response was induced in primary tumors and in pre-metastatic and metastatic lymph nodes. In control lymph nodes, lymphatic vessels were confined to the cortex. In contrast, an enlargement and expansion of lymphatic vessels towards paracortical and medullar areas occurred in pre-metastatic lymph nodes. We designed an original computerized-assisted quantification method to examine the lymphatic vessel structure and the spatial distribution. This new reliable and accurate model is suitable for in vivo studies of lymphangiogenesis, holds promise for unraveling the mechanisms underlying lymphatic metastases and pre-metastatic niche formation in lymph nodes, and will provide new tools for drug testing. [less ▲]

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See detailTroubles du comportement alimentaire et régulation émotionnelle
Englebert, Jérôme ULg

in Psychosomatique Relationnelle (2017), 7

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See detailA water retention model for compacted bentonites
Dieudonné, Anne-Catherine ULg; Della Vecchia, Gabriele; Charlier, Robert ULg

in Canadian Geotechnical Journal (2017)

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See detailRegeneration after fire in campo rupestre: Short- and long-term vegetation dynamics
Le Stradic, Soizig ULg; Hernandez, P.; Fernandes, G. W. et al

in Flora: Morphology, Distribution, Functional Ecology of Plants (2017)

The Cerrado (Brazilian savanna) is the second largest biome in Brazil, covering 22% of the country, and campo rupestre is one of the most biodiverse ecosystem. Campo rupestre are extremely old mountaintop ... [more ▼]

The Cerrado (Brazilian savanna) is the second largest biome in Brazil, covering 22% of the country, and campo rupestre is one of the most biodiverse ecosystem. Campo rupestre are extremely old mountaintop tropical ecosystems, composed of a mosaic of herbaceous, shrubland and savanna vegetation, generally located above 900. m above sea level characterized by shallow, acidic and nutrient-poor soils. In the context of increased land-use changes, effective conservation and management projects appear necessary to guarantee the conservation of these ecosystems. Although fire is a natural disturbance in campo rupestre, the effects of fire on vegetation dynamics remain poorly understood. Our objective was to assess the effects of fire on vegetation recovery and plant composition on both the short- and long-term in the main herbaceous vegetation types: the sandy and stony grasslands. We monitored plant community composition before and after a wildfire in order to assess the short-term vegetation recovery. Diachronic analyses of grasslands burnt at various dates were used to understand the effects of fire on the long-term vegetation dynamics. Our results highlighted a rapid recovery of campo rupestre vegetation after wildfires, suggesting a high adaptation to fire of plant communities. We did not find a significant variation in species richness of sandy grasslands according to time after fire, whereas higher species richness was observed in the recently burnt stony grasslands. No change in plant composition of campo rupestre in response to fire was highlighted, probably due to the high heterogeneity of this ecosystem. After fire, biomass gradually increased over time in both vegetation types. High biomass accumulation could lead to stronger fires. Further studies are necessary to understand the relationship between biomass accumulation and fire intensity in campo rupestre in order to set up adapted fire management strategies to conserve campo rupestre biodiversity. © 2017 Elsevier GmbH. [less ▲]

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See detailPreterm Infant Growth Velocity Calculations: A Systematic Review
Fenton, Tanis; Chan, Hilton; Madhu, Aiswarya et al

in Pediatrics (2017), 139(3), 1-10

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See detailAllogeneic stem cell transplantation for patients with myelodysplastic syndrome 70 years of age or older: A retrospective study of the MDS subcommittee of the Chronic Malignancies Working Party (CMWP) of the EBMT
Heidenreich, S; Ziagkos, D; De Wreede, L et al

in Biology of Blood & Marrow Transplantation (2017), 23

In this retrospective analysis we evaluated the outcome of 313 patients aged ≥ 70 years in the registry of the European Group for Blood and Marrow Transplantation with myelodysplastic syndrome (MDS; n ... [more ▼]

In this retrospective analysis we evaluated the outcome of 313 patients aged ≥ 70 years in the registry of the European Group for Blood and Marrow Transplantation with myelodysplastic syndrome (MDS; n = 221) and secondary acute myeloid leukemia (n = 92) who underwent allogeneic hematopoietic stem cell transplantation (HSCT) from related (n = 79) or unrelated (n = 234) donors. Median age at HSCT was 72 years (range, 70 to 78). Conditioning regimen was nonmyeloablative (n = 54), reduced intensity (n = 207), or standard intensity (n = 52). Allogeneic HSCT for MDS patients ≥ 70 years was increasingly performed over time. Although during 2000 to 2004 only 16 patients received HSCT, during 2011 to 2013 the number of transplantations increased to 181. The cumulative incidence of nonrelapse mortality at 1 year and relapse at 3 years was 32% and 28%, respectively, with a 3-year overall survival rate of 34%. Good performance, determined by Karnofsky performance status, and recipients’ seronegativity for cytomegalovirus was associated with 3-year estimated overall survival rates of 43% (P = .01) and 46% (P = .002), respectively. Conditioning intensity did not impact survival. After careful patient selection, allogeneic HSCT can be offered to patients older than 70 years with MDS. [less ▲]

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See detailSustainability and management control. Exploring and theorizing control patterns in large European firms
Crutzen, Nathalie ULg; Zvezdov, Dimitar; Schaltegger, Stefan

in Journal of Cleaner Production (2017), 143

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See detailIntentionalisme et phénoménologie de l'intentionnalité
Seron, Denis ULg

in Etudes Phénoménologiques - Phenomenological Studies (2017), 1

This paper presents an argument in favor of a “phenomenological” approach to intentionality. This approach, as I see it, involves the view that intentional facts are better expressed with the help of ... [more ▼]

This paper presents an argument in favor of a “phenomenological” approach to intentionality. This approach, as I see it, involves the view that intentional facts are better expressed with the help of appearance words (“seems”, “appears”, “is similar to”, etc.). By contrast, what I call the “intentionalist approach” assumes that intentional facts are better expressed by intentional verbs. The argument is as follows. First, it is well-known that the use of intentional verbs to express typically intentional facts generates anomalies with respect to existential generalization, substitution of identicals, and the principle of excluded middle. Secondly, I argue that the use of appearance words does not generate the same anomalies, which suggests that appearance words are more appropriate to describe intentional facts. This, I conclude, is an argument for preferring the phenomenological to the intentionalist approach to intentionality. [less ▲]

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See detailCombination of Partial Least Squares regression and Design of Experiments to model the retention of pharmaceuticals in Supercritical Fluid Chromatography
Andri, Bertyl ULg; Dispas, Amandine ULg; Marini Djang'Eing'A, Roland ULg et al

in Journal of Chromatography. A (2017)

This work presents a first attempt to establish a model of the retention behaviour for pharmaceutical compounds in gradient mode SFC. For this purpose, multivariate statistics were applied on the basis of ... [more ▼]

This work presents a first attempt to establish a model of the retention behaviour for pharmaceutical compounds in gradient mode SFC. For this purpose, multivariate statistics were applied on the basis of data gathered with the Design of Experiment (DoE) methodology. It permitted to build optimally the experiments needed, and served as a basis for providing relevant physicochemical interpretation of the effects observed. Data gathered over a broad experimental domain enabled the establishment of well-fit linear models of the retention of the individual compounds in presence of methanol as co-solvent. These models also allowed the appreciation of the impact of each experimental parameter and their factorial combinations. This approach was carried out with two organic modifiers (i.e. methanol and ethanol) and provided comparable results. Therefore, it demonstrates the feasibility to model retention in gradient mode SFC for individual compounds as a function of the experimental conditions. This approach also permitted to highlight the predominant effect of some parameters (e.g. gradient slope and pressure) on the retention of compounds. Because building of individual models of retention was possible, the next step considered the estab- lishment of a global model of the retention to predict the behaviour of given compounds on the basis of, on the one side, the physicochemical descriptors of the compounds (e.g. Linear Solvation Energy Relationship (LSER) descriptors) and, on the other side, of the experimental conditions. This global model was established by means of partial least squares regression for the selected compounds, in an experimental domain defined by the Design of Experiment (DoE) methodology. Assessment of the model’s predic- tive capabilities revealed satisfactory agreement between predicted and actual retention (i.e. R2 = 0.942, slope = 1.004) of the assessed compounds, which is unprecedented in the field. [less ▲]

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See detailEffects of non-invasive vagus nerve stimulation on attack frequency over time and expanded response rates in patients with chronic cluster headache: a post hoc analysis of the randomised, controlled PREVA study
Gaul, Charly; MAGIS, Delphine ULg; Liebler, Eric et al

in Journal of Headache and Pain (2017), 18

Background: In the PREVention and Acute treatment of chronic cluster headache (PREVA) study, attack frequency reductions from baseline were significantly more pronounced with non-invasive vagus nerve ... [more ▼]

Background: In the PREVention and Acute treatment of chronic cluster headache (PREVA) study, attack frequency reductions from baseline were significantly more pronounced with non-invasive vagus nerve stimulation plus standard of care (nVNS + SoC) than with SoC alone. Given the intensely painful and frequent nature of chronic cluster headache attacks, additional patient-centric outcomes, including the time to and level of therapeutic response, were evaluated in a post hoc analysis of the PREVA study. Findings: After a 2-week baseline phase, 97 patients with chronic cluster headache entered a 4-week randomised phase to receive nVNS + SoC (n = 48) or SoC alone (n = 49). All 92 patients who continued into a 4-week extension phase received nVNS + SoC. Compared with SoC alone, nVNS + SoC led to a significantly lower mean weekly attack frequency by week 2 of the randomised phase; the attack frequency remained significantly lower in the nVNS + SoC group through week 3 of the extension phase (P < 0.02). Attack frequencies in the nVNS + SoC group were significantly lower at all study time points than they were at baseline (P < 0.05). Response rates were significantly greater with nVNS + SoC than with SoC alone when response was defined as attack frequency reductions of ≥25%, ≥50%, and ≥75% from baseline (≥25% and ≥50%, P < 0.001; ≥75%, P = 0.009). The 100% response rate was 8% with nVNS + SoC and 0% with SoC alone. Conclusions: Prophylactic nVNS led to rapid, significant, and sustained reductions in chronic cluster headache attack frequency within 2 weeks after its addition to SoC and was associated with significantly higher ≥25%, ≥50%, and ≥75% response rates than SoC alone. The rapid decrease in weekly attack frequency justifies a 4-week trial period to identify responders to nVNS, with a high degree of confidence, among patients with chronic cluster headache. [less ▲]

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See detailIntegrating biological indicators in a Soil Monitoring Network (SMN) to improve soil quality diagnosis – a study case in Southern Belgium (Wallonia)
Krüger, Inken ULg; Chartin, Caroline; van Wesemael, Bas et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment (2017), 31(S1),

Soil organisms and their activities are essential for soil ecosystem functioning and they can thus be used as pertinent indicators of soil quality. Recent efforts have been undertaken to include ... [more ▼]

Soil organisms and their activities are essential for soil ecosystem functioning and they can thus be used as pertinent indicators of soil quality. Recent efforts have been undertaken to include biological indicators of soil quality into regional/national monitoring networks. Objectives. The aim of this study was to provide a first dataset of six biological indicators and two eco-physiological quotients for two landscape units in Wallonia. These spatial units are characterized by homogeneous climate conditions, soil type, land-use and management (here, grasslands in the Ardennes, and croplands in the Loam Region). Method. Respiration potential, microbial biomass carbon and nitrogen, net nitrogen mineralization, metabolic potential of soil bacteria and earthworm abundance were measured at a total of 60 sites in two different landscape units (LSU). Variability within each LSU was studied. Data was synthesized through calculation of a comprehensive score and presentation as radar plots. Results. All selected biological indicators were significantly higher under grassland than under cropland soils, highlighting the biological indicators’ power of discrimination between main land use types. Variability within LSU depended on the biological indicator and was generally higher in grassland than in cropland soils. Each site could unambiguously be assigned to its landscape unit based on its calculated comprehensive score. Radar plots allowed an assessment of the distribution of values within a landscape unit at a glance. Conclusions. The pilot-study defined the first baseline values for agricultural soils in Wallonia and laid the foundation for a monitoring network of biological soil quality. [less ▲]

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See detailEvaluation of the long-term effect of biochar on properties of temperate agricultural soil at pre-industrial charcoal kiln sites in Wallonia, Belgium
Hardy, Brieuc; Cornelis, Jean-Thomas ULg; Houben, David et al

in European Journal of Soil Science (2017), 68

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See detailRoad and intermodal transport performance: the impact of operational costs and air pollution external costs
Mostert, Martine ULg; Caris, An; Limbourg, Sabine ULg

in Research in Transportation Business & Management (2017)

The transportation of goods is essential for the economy, but it also contributes to air pollution which, in turn, affects human health. These negative impacts generate additional costs for society that ... [more ▼]

The transportation of goods is essential for the economy, but it also contributes to air pollution which, in turn, affects human health. These negative impacts generate additional costs for society that are not necessarily taken into account in public transportation policies and in private transportation decisions of companies and individuals. This leads to inefficient transportation systems where the social equilibrium is not reached. Intermodal transport is promoted by the European Commission to reduce these negative externalities. The objective of this paper is to analyze at a strategic level the effect on modal split between road, intermodal rail and intermodal inland waterway transport of several economic or environmental policies. An intermodal allocation model is applied to the Belgian case in order to identify the modal split changes between the single minimization of costs (operational or health-related external) and the introduction of additional road taxes. [less ▲]

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See detailNumerical modelling of microscopic lubricant flow in sheet metal forming. Application to plane strip drawing
Carretta, Yves; Bech, Jacob; Legrand, Nicolas et al

in International Journal for Numerical Methods in Engineering (2017)

This paper presents a numerical investigation of microscopic lubricant flows from the cavities to the plateaus of the surface roughness of metal sheets during forming processes. This phenomenon, called ... [more ▼]

This paper presents a numerical investigation of microscopic lubricant flows from the cavities to the plateaus of the surface roughness of metal sheets during forming processes. This phenomenon, called micro-plastohydrodynamic lubrication, was observed experimentally in various situations such as compression sliding tests, strip drawing and cold rolling. It leads to local friction drop and wear reduction. It is therefore critical to achieve a good understanding of this phenomenon. As to move towards that goal, a multiscale fluid–structure interaction model is developed to model lubricant flows at the microscopic scale. These simulations are made possible through the use of the Arbitrary Lagrangian Eulerian (ALE) formalism. In this paper, this methodology is used to study plane strip drawing. The numerical model is able to predict the onset of lubricant escape and the amount of lubricant flowing on the plateaus. Numerical results exhibit good agreement with experimental measurements. [less ▲]

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See detailFactors associated with reaching or not reaching target HbA1c after initiation of basal or premixed insulin in patients with type 2 diabetes.
Scheen, André ULg; Schmitt, H.; Jiang, H. H. et al

in Diabètes & Métabolism (2017), 43(69-78),

AIMS: To evaluate factors associated with reaching or not reaching target glycated haemoglobin (HbA1c) levels by analysing the respective contributions of fasting hyperglycaemia (FHG), also referred to as ... [more ▼]

AIMS: To evaluate factors associated with reaching or not reaching target glycated haemoglobin (HbA1c) levels by analysing the respective contributions of fasting hyperglycaemia (FHG), also referred to as basal hyperglycaemia, vs postprandial hyperglycaemia (PHG) before and after initiation of a basal or premixed insulin regimen in patients with type 2 diabetes. METHODS: This post-hoc analysis of insulin-naive patients in the DURABLE study randomised to receive either insulin glargine or insulin lispro mix 25 evaluated the percentages of patients achieving a target HbA1c of <7.0% (<53mmol/mol) per baseline HbA1c quartiles, and the effect of each insulin regimen on the relative contributions of PHG and FHG to overall hyperglycaemia. RESULTS: Patients had comparable demographic characteristics and similar HbA1c and FHG values at baseline in each HbA1c quartile regardless of whether they reached the target HbA1c. The higher the HbA1c quartile, the greater was the decrease in HbA1c, but also the smaller the percentage of patients achieving the target HbA1c. HbA1c and FHG decreased more in patients reaching the target, resulting in significantly lower values at endpoint in all baseline HbA1c quartiles with either insulin treatment. Patients not achieving the target HbA1c had slightly higher insulin doses, but lower total hypoglycaemia rates. CONCLUSION: Smaller decreases in FHG were associated with not reaching the target HbA1c, suggesting a need to increase basal or premixed insulin doses to achieve targeted fasting plasma glucose and improve patient response before introducing more intensive prandial insulin regimens. [less ▲]

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See detailPreparing physically educated citizens in physical education. Expectations and practices
Cloes, Marc ULg

in Retos (2017), 31

Since physical education (PE) became a compulsory school subject, its objectives have often been related to the expectations of society. Since the turn of the new millennium, this has resulted in PE being ... [more ▼]

Since physical education (PE) became a compulsory school subject, its objectives have often been related to the expectations of society. Since the turn of the new millennium, this has resulted in PE being increasingly linked to the promotion of physically active lifestyles. In this paper, we try to determine whether practitioners have the capacity to reach recent objectives for the subject or should reconsider their work on this issue. Moreover, we propose to extend the current focus on physical literacy to encompass the concept of societal transfer, underlining the need for an authentic pedagogy of PE. [less ▲]

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See detailFamilial history of migraine influences habituation of visual evoked potentials
Lisicki Martinez, Marco ULg; Ruiz-Romagnoli, Emiliano; D'Ostilio, Kevin ULg et al

in Cephalalgia : An International Journal of Headache (2017)

Background: Lack of habituation of visual evoked potentials (VEP) is a common finding in migraine patients between attacks. Previous studies have suggested an electrophysiological familial aggregation ... [more ▼]

Background: Lack of habituation of visual evoked potentials (VEP) is a common finding in migraine patients between attacks. Previous studies have suggested an electrophysiological familial aggregation pattern associated with migraine. The aim of this study was to evaluate the influence of a positive familial history of migraine on VEP amplitude and habituation. Methods: We recorded six blocks of 100 VEP during continuous pattern-reversal stimulation in 30 patients with migraine between attacks (MO) and in 30 healthy volunteers, of whom 15 had a first-degree relative suffering from migraine (HVm) and 15 had not (HV). Results: Both MO and HVm had a significant deficit of VEP habituation and similarly reduced N1-P1 first block amplitudes, compared to HV (habituation slope: MO ¼ 0.033, HVm ¼ 0.021, HV ¼ 0.025, HV vs. MO p ¼ 0.002, HV vs. HVm p ¼ 0.036; mean N1-P1 amplitude in the first block: MO ¼ 9.08 mV, HVm ¼ 9.29 mV, HV ¼ 12.19 mV. HV vs. MO p ¼ 0.041, HV vs. HVm p ¼ 0.076). The first block N1-P1 amplitude was negatively correlated with the habituation slope for both MO (r ¼ .44, p ¼ 0.015) and HVm (r ¼ .56, p ¼ 0.031) while no significant correlation was found in HV (r ¼ .17, p ¼ 0.53). There were no differences in VEP latencies between the groups. Conclusions: Our study suggests that lack of habituation of visual evoked potentials is probably a genetically determined endophenotypic trait that is associated with both migraine and migraine susceptibility. We hypothesize that genetic diversity of populations could account for some of the discrepancies between electrophysiological studies performed in migraine and for interindividual variations among the subgroups. [less ▲]

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See detailP-301 High Concentration Multistrain Probiotic Produced at Different Manufacturing Sites: Comparative Analysis.
Lombardi, Francesca; La Torre, Cristina; Giusti, Ilaria et al

in Inflammatory Bowel Diseases (2017), 23

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See detailPest regulation and support of natural enemies in agriculture: Experimental evidence of within field wildflower strips
Hatt, Séverin ULg; Chevalier Mendes Lopes, Thomas ULg; Boeraeve, Fanny ULg et al

in Ecological Engineering (2017), 98

tRestoring ecosystem services in agriculture is vital to reach a sustainable food production. More specif-ically, developing farming practices which enhance biological pest control is a main issue for ... [more ▼]

tRestoring ecosystem services in agriculture is vital to reach a sustainable food production. More specif-ically, developing farming practices which enhance biological pest control is a main issue for today’sagriculture. The aim of this study was to assess whether the two strategies of complicating the search ofhost plants by pests by increasing plant diversity, and of supporting their natural enemies by managinghabitats, could be combined simultaneously at the field scale to restore biological pest control and reducechemical insecticide use. In Gembloux (Belgium), wildflower strips (WFS) were sown within wheat cropsin which pests (i.e., aphids), their predators (i.e. aphidophagous hoverflies, lacewings and ladybeetles)and parasitoid wasps were monitored for 10 weeks in the period of May through July 2015 as indicatorsof the ES of pest control. Aphids were significantly reduced and adult hoverflies favoured in wheat inbetween WFS, compared to monoculture wheat plots. No significant differences were observed for adultlacewings, ladybeetles and parasitoids. In all treatments, very few lacewing and ladybeetle larvae wereobserved on wheat tillers. The abundance of hoverfly larvae was positively correlated with the aphid den-sity on tillers in between WFS, showing that increasing food provisions by multiplying habitats withinfields, and not only along margins, can help supporting aphidophagous hoverflies in crops. By enhancingthe ecosystem services of biological pest control, this study shows that increasing both plant diversityand managing habitats for natural enemies may reduce aphid populations, hence insecticide use. Futureresearch should continue this vein of work by quantifying the link between agricultural practices and thedelivery of ecosystem services in order to guide future measures of agricultural policies. [less ▲]

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See detailEfficient ANOVA for directional data
Ley, Christophe; Swan, Yvik ULg; Verdebout, Thomas

in Annals of the Institute of Statistical Mathematics (2017)

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See detailCabergoline for Cushing's disease: a large retrospective multicenter study.
Ferriere, A.; Cortet, C.; Chanson, P. et al

in European Journal of Endocrinology (2017), 176(3), 305-314

OBJECTIVE: The efficacy of cabergoline in Cushing's disease (CD) is controversial. The aim of this study was to assess the efficacy and tolerability of cabergoline in a large contemporary cohort of ... [more ▼]

OBJECTIVE: The efficacy of cabergoline in Cushing's disease (CD) is controversial. The aim of this study was to assess the efficacy and tolerability of cabergoline in a large contemporary cohort of patients with CD. DESIGN: We conducted a retrospective multicenter study from thirteen French and Belgian university hospitals. METHODS: Sixty-two patients with CD received cabergoline monotherapy or add-on therapy. Symptom score, biological markers of hypercortisolism and adverse effects were recorded. RESULTS: Twenty-one (40%) of 53 patients who received cabergoline monotherapy had normal urinary free cortisol (UFC) values within 12 months (complete responders), and five of these patients developed corticotropic insufficiency. The fall in UFC was associated with significant reductions in midnight cortisol and plasma ACTH, and with clinical improvement. Compared to other patients, complete responders had similar median baseline UFC (2.0 vs 2.5xULN) and plasma prolactin concentrations but received lower doses of cabergoline (1.5 vs 3.5 mg/week, P < 0.05). During long-term treatment (>12 months), cabergoline was withdrawn in 28% of complete responders because of treatment escape or intolerance. Overall, sustained control of hypercortisolism was obtained in 23% of patients for 32.5 months (19-105). Nine patients on steroidogenesis inhibitors received cabergoline add-on therapy for 19 months (1-240). Hypercortisolism was controlled in 56% of these patients during the first year of treatment with cabergoline at 1.0 mg/week (0.5-3.5). CONCLUSIONS: About 20-25% of CD patients are good responders to cabergoline therapy allowing long-term control of hypercortisolism at relatively low dosages and with acceptable tolerability. No single parameter, including the baseline UFC and prolactin levels, predicted the response to cabergoline. [less ▲]

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See detailAb initio study of hydrogenic effective mass impurities in Si nanowires
Peelaers, Hartwin; Durgun, Engin; Partoens, Bart et al

in Journal of Physics : Condensed Matter (2017), 29

The effect of B and P dopants on the band structure of Si nanowires is studied using electronic structure calculations based on density functional theory. At low concentrations a dispersionless band is ... [more ▼]

The effect of B and P dopants on the band structure of Si nanowires is studied using electronic structure calculations based on density functional theory. At low concentrations a dispersionless band is formed, clearly distinguishable from the valence and conduction bands. Although this band is evidently induced by the dopant impurity, it turns out to have purely Si character. These results can be rigorously analyzed in the framework of effective mass theory. In the process we resolve some common misconceptions about the physics of hydrogenic shallow impurities, which can be more clearly elucidated in the case of nanowires than would be possible for bulk Si. We also show the importance of correctly describing the effect of dielectric confinement, which is not included in traditional electronic structure calculations, by comparing the obtained results with those of G0W0 calculations. [less ▲]

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See detailOn the numerical simulation of sheet metal blanking process
Canales Cardenas, Cristian ULg; Bussetta, Philippe; Ponthot, Jean-Philippe ULg

in International Journal of Material Forming (2017), 10

The use of the blanking process has been widely spread in mass production industries. In this technique, the quality of the final product is directly related to the setting parameters of the process and ... [more ▼]

The use of the blanking process has been widely spread in mass production industries. In this technique, the quality of the final product is directly related to the setting parameters of the process and the material response of the sheet. In the present work, a general framework based on the finite element method for the simulation of the sheet metal blanking process is presented. The proposed approach properly addresses all the numerical challenges related to blanking. First, an extension of elasto-viscoplastic constitutive equations for the large strain regime is used to take into account the material strain-rate sensitivity. Then, the inertial effects coming from high velocity operations are considered by means of an implicit time integration scheme. Moreover, the frictional contact interactions are simulated with the classical Coulomb law and an energetically consistent formulation of area regularization. Finally, ductile fracture is modeled thanks to the element deletion method coupled with a fracture criterion. The blanking process is then simulated for different setting parameters. The accuracy of this approach is evaluated by comparing the numerical predictions to experimental results for both quasi-static and dynamic conditions. Good agreement is found between experimental and numerical results for all cases. [less ▲]

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See detailIntermodal network design: a three-mode bi-objective model applied to the case of Belgium
Mostert, Martine ULg; Caris, An; Limbourg, Sabine ULg

in Flexible Services and Manufacturing Journal (2017)

Freight transport planning is nowadays encouraged to align with environmental objectives. Among those, climate change is of particular interest for many countries. In its White Paper on Transport, the ... [more ▼]

Freight transport planning is nowadays encouraged to align with environmental objectives. Among those, climate change is of particular interest for many countries. In its White Paper on Transport, the European Commission considers intermodal transport as a potential solution for reducing environmental impacts. In order to make good strategic transport decisions, realistic decision support models for freight transport networks must be developed, so that insights can be derived for the different stakeholders of the transportation chain. This research proposes a bi-objective mathematical formulation which takes into account economic and environmental objectives, on a road and intermodal network with three modes of transport (road, intermodal rail, and intermodal inland waterways), and in which economies of scale of intermodal transport can be considered. With this model better fitting reality, an application to the Belgian case study provides practical information on how flows, terminal types and locations vary depending on the chosen policy, on the integration or not of economies of scale, on costs or emissions modifications and on the number of terminals to locate. Results show that the chosen policy influences the terminal type and the intermodal market share. The study also highlights the interest of intermodal transport on short distances, and the risk of flow exchanges inside the intermodal market share, rather than between road and intermodal transport. [less ▲]

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See detailMacroevolution of Specificity in Cyanolichens of the Genus Peltigera Section Polydactylon (Lecanoromycetes, Ascomycota)
Magain, Nicolas ULg; Miadlikoswka, Jolanta; Goffinet, Bernard et al

in Systematic Biology (2017), 66(1), 74-99

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See detailContrasted terrace systems of the lower Moulouya river as indicator of crustal deformation in NE Morocco
Rixhon, Gilles; Bartz, Melanie; El Ouahabi, Meriam ULg et al

in Journal of African Earth Sciences (2017)

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See detailFuture-oriented mental time travel in individuals with disordered gambling.
Noel, Xavier; Saeremans, Melanie; Kornreich, Charles et al

in Consciousness & Cognition (2017), 49

This study investigated the ability of individuals with disordered gambling to imagine future events. Problem gamblers (n=35) and control participants (n=35) were asked to imagine positive and negative ... [more ▼]

This study investigated the ability of individuals with disordered gambling to imagine future events. Problem gamblers (n=35) and control participants (n=35) were asked to imagine positive and negative future events for three temporal distances (one week, one year, 5-10years). Then, a variety of phenomenological aspects of their future thoughts (e.g., sensory and contextual details, autonoetic consciousness) were rated. Compared to control subjects, problem gamblers generated fewer positive and negative events across all temporal distances, an impairment that was correlated to verbal fluency scores. Furthermore, problem gamblers rated imagined events as containing fewer sensory and contextual details, and lacking autonoetic consciousness. These findings demonstrate that problem gambling is associated with a reduced future-oriented mental time travel ability and, in particular, with diminished autonoetic consciousness when imagining future events. [less ▲]

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See detailAeroservoelastic Simulations for Horizontal Axis Wind Turbines
Prasad, Chandra Shekhar ULg; Chen, Qiong Zhong; Bruls, Olivier ULg et al

in Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy (2017), 231(2), 103-117

This paper describes the development of a complete methodology for the aeroservoelastic modeling of horizontal axis wind turbines at the conceptual design stage. The methodology is based on the ... [more ▼]

This paper describes the development of a complete methodology for the aeroservoelastic modeling of horizontal axis wind turbines at the conceptual design stage. The methodology is based on the implementation of unsteady aerodynamic modeling, advanced description of the control system and nonlinear finite element calculations in the SWT wind turbine design package. The aerodynamic modeling is carried out by means of fast techniques, such as the Blade Element Method and the unsteady Vortex Lattice Method, including a free wake model. The complete model also includes a description of a doubly fed induction generator and its control system for variable speed operation. The SWT software features a non-linear finite element solver with multi-body dynamics capability. The full methodology is used to perform complete aeroservoelastic simulations of a realistic 2MW wind turbine model. The interaction between the three components of the approach is carefully analyzed and presented here. [less ▲]

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See detailFifth European Dirofilaria and Angiostrongylus Days (FiEDAD) 2016
Simón, F.; Kartashev, V.; González-Miguel, J. et al

in Parasites & Vectors (2017), 10(1), 5

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See detailInterpreting ‘grief’ in Senegal: language, emotions and cross-cultural translation in a francophone African context
Ruth, Evans; Jane; Fatou, Kebe et al

in Mortality (2017)

This article reflects on the profound complexities of translating and interpreting ‘grief’, and emotions and responses to death more broadly, in multilingual, cross-cultural contexts. Drawing on ... [more ▼]

This article reflects on the profound complexities of translating and interpreting ‘grief’, and emotions and responses to death more broadly, in multilingual, cross-cultural contexts. Drawing on qualitative research conducted in urban Senegal, West Africa, we discuss the exchange of meanings surrounding grief and death through language, including the process of translation, in its broadest sense, between multiple languages (Wolof, French, English). Our experiences demonstrate the crucial importance of involving interpreters and field researchers throughout the research process, to gain fundamental insight into the cultural nuances of indigenous languages and how these are translated and potentially re-framed in the process. We reflect on our iterative process of discussing emerging interpretations with participants in follow-up workshops and with our interpreter. This approach helped shed light on language use surrounding ‘grief’ and how this is bound up with wider socio-cultural norms which make particular emotions surrounding death and experiences/meanings of death and bereavement possible and ‘speak-able’. Our research calls for greater recognition in death and bereavement studies of the cultural specificity of conceptual frameworks developed in minority European socio-linguistic contexts and demonstrates the need for greater engagement with theoretical, empirical and methodological insights gained in diverse cultural contexts in the Majority world. [less ▲]

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See detailAntiplasmodial activity of Mezoneuron benthamianum leaves and identification of its active constituents
Jansen, Olivia ULg; Tchinda, Alembert T.; Loua, Jean et al

in Journal of Ethnopharmacology (2017), 203(March), 20--26

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See detailA vertebrate specific and essential role for sp7/osterix in osteogenesis revealed by gene knock-out in the teleost medaka.
Yu, T; Graf, M; Renn, Jörg ULg et al

in Development (2017), 144(2), 265-271

Sp7/osterix (osx) encodes a zinc-finger transcription factor that controls osteoblast differentiation in mammals. Although identified in all vertebrate lineages, its role in non-mammalian bone formation ... [more ▼]

Sp7/osterix (osx) encodes a zinc-finger transcription factor that controls osteoblast differentiation in mammals. Although identified in all vertebrate lineages, its role in non-mammalian bone formation remains elusive. Here we show that an osx mutation in medaka results in severe bone defects and larval lethality. Pre-osteoblasts fail to differentiate leading to severe intramembranous and perichondral ossification defects. The notochord sheath mineralizes normally supporting the idea of an osteoblast-independent mechanism for teleost vertebral centra formation. This study establishes a key role for Sp7/Osx for bone formation also in a non-mammalian species, and reveals conserved and non-conserved features in vertebrate bone formation. [less ▲]

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See detailNew computational method of the ball/race contacts transverse loads of high speed ball bearings without race control hypothesis
Servais, Christophe ULg

in Tribology International (2017)

Some hypotheses are still necessary in order to access the ball bearing Newtonian equilibrium with quasi-static methods. Among these hypotheses are the values of the transverse loads within ball/race ... [more ▼]

Some hypotheses are still necessary in order to access the ball bearing Newtonian equilibrium with quasi-static methods. Among these hypotheses are the values of the transverse loads within ball/race contacts. Those loads are due to the gyroscopic torques. Nowadays, the transverse loads are estimated without any equilibrium criterion by the specialized literature. Moreover, the race control assumption is often employed in addition to the hypotheses made about the transverse loads. The paper describes a new method to compute the transverse loads without using the race control assumption. Then, a correlation between the ball bearing kinematics and the transverse loads is established. It leads to an accurate and efficient computational method to access the Newtonian equilibrium of high speed ball bearings. [less ▲]

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See detailMiddle Miocene climate and vegetation models and their validation with proxy data
Henrot, Alexandra-Jane ULg; Utescher, Torsten; Erdei, Boglarka et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (2017), 467

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See detailPhotoreversibility and biocompatibility of polydimethylsiloxane-coumarin as adjustable intraocular lens material
Jellali, Rachid; Bertrand, Virginie ULg; Alexandre, Michaël et al

in Macromolecular Bioscience (2017)

Polydimethylsiloxane (PDMS) constitutes an interesting material for a variety of biomed- ical applications, especially as intraocular lenses (IOLs), for its excellent transparency. In this work, a ... [more ▼]

Polydimethylsiloxane (PDMS) constitutes an interesting material for a variety of biomed- ical applications, especially as intraocular lenses (IOLs), for its excellent transparency. In this work, a photoreversible PDMS-coumarin network, whose shape and properties can be adjusted postoperatively in a noninvasive manner, is developed. The synthesis of PDMS-cou- marin is achieved by amidation of a coumarin acid chloride derivative with amine-function- alized PDMSs. Under exposure of λ > 300 nm, these polymers can be cured by dimerization of coumarin. The cured polymers can be uncrosslinked via photocleavage of cyclobutane dimers upon illumination at λ < 290 nm. The diffusion of linear PDMSs in a crosslinked network and the controlled shape modification are studied, which demonstrate that these polymers are good candidates for adjustable IOL application. IOL disks prepared from these materials show high hydrophobicity and good transparency. In vitro cytotoxicity, lens epithelial cell adhesion assays, and rabbit host reaction against implanted disks demonstrate the biocompatibility of the polymer. [less ▲]

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See detailRange size heritability and diversification patterns in the liverwort genus Radula
Patiño, J.; Wang, J.; Renner, M.A.M. et al

in Molecular Phylogenetics & Evolution (2017), 106

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See detailPitfalls in supermatrix phylogenomics
Philippe, Hervé; Vienne, Damien M. De; Ranwez, Vincent et al

in European Journal of Taxonomy (2017), 283

In the mid-2000s, molecular phylogenetics turned into phylogenomics, a development that improved the resolution of phylogenetic trees through a dramatic reduction in stochastic error. While some then ... [more ▼]

In the mid-2000s, molecular phylogenetics turned into phylogenomics, a development that improved the resolution of phylogenetic trees through a dramatic reduction in stochastic error. While some then predicted “the end of incongruence”, it soon appeared that analysing large amounts of sequence data without an adequate model of sequence evolution amplifies systematic error and leads to phylogenetic artefacts. With the increasing flood of (sometimes low-quality) genomic data resulting from the rise of high-throughput sequencing, a new type of error has emerged. Termed here “data errors”, it lumps together several kinds of issues affecting the construction of phylogenomic supermatrices (e.g., sequencing and annotation errors, contaminant sequences). While easy to deal with at a single-gene scale, such errors become very difficult to avoid at the genomic scale, both because hand curating thousands of sequences is prohibitively time-consuming and because the suitable automated bioinformatics tools are still in their infancy. In this paper, we first review the pitfalls affecting the construction of supermatrices and the strategies to limit their adverse effects on phylogenomic inference. Then, after discussing the relative non-issue of missing data in supermatrices, we briefly present the approaches commonly used to reduce systematic error. [less ▲]

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See detailDermatophytes and Dermatophytoses: A Thematic Overview of State of the Art, and the Directions for Future Research and Developments
Bouchara, JP; Mignon, Bernard ULg; Chaturvedi, V

in Mycopathologia (2017), 182(1), 1-4

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See detailSedation of Patients With Disorders of Consciousness During Neuroimaging: Effects on Resting State Functional Brain Connectivity.
KIRSCH, Murielle ULg; Guldenmund, P; Ali Bahri, Mohamed et al

in Anesthesia and Analgesia (2017), 124(2),

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See detailSpaces Snu, diametral dimension and property Omega bar
Demeulenaere, Loïc ULg

in Journal of Mathematical Analysis and Applications (2017), 449(2), 1340-1350

This paper investigates two topological invariants in the context of the sequence spaces Snu, which are metric topological vector spaces defined in order to study the regularity of signals. First, it ... [more ▼]

This paper investigates two topological invariants in the context of the sequence spaces Snu, which are metric topological vector spaces defined in order to study the regularity of signals. First, it extends the formula already known of the diametral dimension of spaces Snu to some non-locally pseudoconvex ones. Second, it proves that locally p-convex spaces Snu verifies the property "Omega id", which is equivalent to Omega bar for Fréchet spaces. [less ▲]

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See detailScale-dependent diffusion anisotropy in nanoporous silicon
Kondrashova, D; Lauerer, A; Mehlhorn, D et al

in Scientific Reports (2017), 7

Nanoporous silicon produced by electrochemical etching of highly B-doped p-type silicon wafers can be prepared with tubular pores imbedded in a silicon matrix. Such materials have found many technological ... [more ▼]

Nanoporous silicon produced by electrochemical etching of highly B-doped p-type silicon wafers can be prepared with tubular pores imbedded in a silicon matrix. Such materials have found many technological applications and provide a useful model system for studying phase transitions under con nement. This paper reports a joint experimental and simulation study of di usion in such materials, covering displacements from molecular dimensions up to tens of micrometers with carefully selected probe molecules. In addition to mass transfer through the channels, di usion (at much smaller rates) is also found to occur in directions perpendicular to the channels, thus providing clear evidence of connectivity. With increasing displacements, propagation in both axial and transversal directions is progressively retarded, suggesting a scale-dependent, hierarchical distribution of transport resistances (“constrictions” in the channels) and of shortcuts (connecting “bridges”) between adjacent channels. The experimental evidence from these studies is con rmed by molecular dynamics (MD) simulation in the range of atomistic displacements and rationalized with a simple model of statistically distributed “constrictions” and “bridges” for displacements in the micrometer range via dynamic Monte Carlo (DMC) simulation. Both ranges are demonstrated to be mutually transferrable by DMC simulations based on the pore space topology determined by electron tomography. [less ▲]

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See detailCOMPUTATIONAL METHODS IN MANUFACTURING
Ponthot, Jean-Philippe ULg; Feulvarch, Eric; Drapier, Sylvain et al

in International Journal of Material Forming (2017), 10

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See detailExperimental observation of the Poincaré-Birkhoff scenario in a driven many-body quantum system
Tomkovic, Jiri; Muessel, Wolfgang; Strobel, Helmut et al

in Physical Review A (2017), 95

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See detailPest and mould infestation of smoked shrimp and preventive measures for storage in cottage industry
Kpoclou; Anihouvi; Azokpota et al

in Indian Journal of Traditional Knowledge (2017), 16

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See detailEffects of reducing blood pressure on renal outcomes in patients with type 2 diabetes: Focus on SGLT2 inhibitors and EMPA-REG OUTCOME.
Scheen, André ULg; Delanaye, P.

in Diabètes & Métabolism (2017), (epub ahead of print),

Empagliflozin, a sodium-glucose cotransporter type 2 (SGLT2) inhibitor, has enabled remarkable reductions in cardiovascular and all-cause mortality as well as in renal outcomes in patients with type 2 ... [more ▼]

Empagliflozin, a sodium-glucose cotransporter type 2 (SGLT2) inhibitor, has enabled remarkable reductions in cardiovascular and all-cause mortality as well as in renal outcomes in patients with type 2 diabetes (T2D) and a history of cardiovascular disease in the EMPA-REG OUTCOME. These results have been attributed to haemodynamic rather than metabolic effects, in part due to the osmotic/diuretic action of empagliflozin and the reduction in arterial blood pressure (BP). The present narrative review includes the results of meta-analyses of trials evaluating the effects on renal outcomes of lowering BP in patients with T2D, with a special focus on the influence of baseline and achieved systolic BP, and compares the renal outcome results of the EMPA-REG OUTCOME with those of other major trials with inhibitors of the renin-angiotensin system in patients with T2D and the preliminary findings with other SGLT2 inhibitors, and also evaluates post hoc analyses from the EMPA-REG OUTCOME of special interest as regards the BP-lowering hypothesis and renal function. While systemic BP reduction associated to empagliflozin therapy may have contributed to the renal benefits reported in EMPA-REG OUTCOME, other local mechanisms related to kidney homoeostasis most probably also played a role in the overall protection observed in the trial. [less ▲]

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See detailHigh resolution (1 km) positive degree-day modelling of Greenland ice sheet surface mass balance, 1870–2012 using reanalysis data
Wilton, D.; Jowett, A.; Hanna, E. et al

in Journal of Glaciology (2017), 63

We show results from a positive degree-day (PDD) model of Greenland ice sheet (GrIS) surface mass balance (SMB), 1870–2012, forced with reanalysis data. The model includes an improved daily temperature ... [more ▼]

We show results from a positive degree-day (PDD) model of Greenland ice sheet (GrIS) surface mass balance (SMB), 1870–2012, forced with reanalysis data. The model includes an improved daily temperature parameterization as compared with a previous version and is run at 1 km rather than 5 km resolution. The improvements lead overall to higher SMB with the same forcing data. We also compare our model with results from two regional climate models (RCMs). While there is good qualitative agreement between our PDD model and the RCMs, it usually results in lower precipitation and lower runoff but approximately equivalent SMB: mean 1979–2012 SMB (± standard deviation), in Gt a−1, is 382 ± 78 in the PDD model, compared with 379 ± 101 and 425 ± 90 for the RCMs. Comparison with in situ SMB observations suggests that the RCMs may be more accurate than PDD at local level, in some areas, although the latter generally compares well. Dividing the GrIS into seven drainage basins we show that SMB has decreased sharply in all regions since 2000. Finally we show correlation between runoff close to two calving glaciers and either calving front retreat or calving flux, this being most noticeable from the mid-1990s. [less ▲]

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See detailLong-term consistency of spatial patterns of primate seed dispersal
Heymann, E. W.; Culot, Laurence ULg; Knogge, Christoph et al

in Ecology and Evolution (2017)

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See detailRobust asymptotic tests for the equality of multivariate coefficients of variation
Aerts, Stéphanie ULg; Haesbroeck, Gentiane ULg

in TEST (2017), 26(1), 163-187

In order to easily compare several populations on the basis of more than one feature, multivariate coefficients of variation (MCV) may be used as they allow to summarize relative dispersion in a single ... [more ▼]

In order to easily compare several populations on the basis of more than one feature, multivariate coefficients of variation (MCV) may be used as they allow to summarize relative dispersion in a single index. However, up to date, no test of equality of one or more MCV's has been developed in the literature. In this paper, several classical and robust Wald type tests are proposed and studied. The asymptotic distributions of the test statistics are derived under elliptical symmetry, and the asymptotic efficiency of the robust versions is compared to the classical tests. Robustness of the proposed procedures is examined through partial influence functions of the test statistic, as well as by means of power and level influence functions. A simulation study compares the performance of the classical and robust tests under uncontaminated and contaminated schemes, and the difference with the usual covariance homogeneity test is highlighted. As a by-product, these tests may also be considered in the univariate context where they yield procedures that are both robust and easy-to-use. They provide an interesting alternative to the numerous parametric tests of comparison of univariate coefficients of variation existing in the literature, which are, in most cases, unreliable in presence of outliers. The methods are illustrated on a real data set. [less ▲]

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See detailChemical Composition and Acaricidal Activity of Thymus algeriensis Essential Oil against Varroa destructor
Kouache, Benmoussa; Brada, Moussa; Saadi, Abdelkader et al

in Natural Product Communications (2017), 12(0), 1-4

The aim of the present study was to determine the chemical composition and evaluate the acaricidal activity of Thymus algeriensis essential oil (TAEO) against Varroa destructor. This ectoparasitic mite is ... [more ▼]

The aim of the present study was to determine the chemical composition and evaluate the acaricidal activity of Thymus algeriensis essential oil (TAEO) against Varroa destructor. This ectoparasitic mite is a pest of the honey bee Apis mellifera. The essential oil from the aerial parts of T. algeriensis, obtained by hydrodistillation, was obtained in a yield of 2.8± 0.2%, w/w. The TAEO was analyzed by GC and GC/MS. Thirty-four compounds were identified, representing 99.3% of the oil. The main constituents were carvacrol (48.4%), γ-terpinene (14.9%), p-cymene (14.7%), and thymol (5.6%). Four lots were constituted at the level of an apiary in order to study the dynamics of the Varroa destructor and its host, Apis mellifera. After diagnosis by the biological method "install of diapers", the lots were treated at different doses of TAEO (0.1, 0.3 and 0.5%). TAEO was sprayed on top of the hives. The results show that TAEO at 0.5% resulted in a decrease in the rate of infestation of Varroa destructor, causing a mortality rate of 32.6% without negative effect on the nesting of the queen. The essential oil of T. algeriensis could be used as a bioacaricidal agent. [less ▲]

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See detailEuropean Network for Neglected Vectors and Vector-Borne Infections COST Action Guidelines: What Is This About and What Is This For?
Charrel, Remi N.; Lempereur, Laetitia ULg; Mihalca, Andrei D. et al

in Vector borne and zoonotic diseases (Larchmont, N.Y.) (2017), 17(1), 1

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See detailStructure impact of two galactomannan fractions on their viscosityproperties in dilute solution, unperturbed state and gel state
Gillet, Sébastien; Aguedo, Mario ULg; Petrut, Raul Flaviu ULg et al

in International Journal of Biological Macromolecules (2017), 96

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See detailInstitutional pedagogy for an autonomous society: Castoriadis & Lapassade
Wustefeld, Sophie ULg

in Educational Philosophy & Theory (2017)

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See detailQuantification of Calabrian vegetation in Southern Primory'e (far East of Russia) using multiple proxies
Bondarenko, O. V.; Blokhina, N. I.; Bruch, A. A. et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (2017), 467

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See detailCounting the number of non-zero coefficients in rows of generalized Pascal triangles
Leroy, Julien ULg; Rigo, Michel ULg; Stipulanti, Manon ULg

in Discrete Mathematics (2017), 340

This paper is about counting the number of distinct (scattered) subwords occurring in a given word. More precisely, we consider the generalization of the Pascal triangle to binomial coefficients of words ... [more ▼]

This paper is about counting the number of distinct (scattered) subwords occurring in a given word. More precisely, we consider the generalization of the Pascal triangle to binomial coefficients of words and the sequence (S(n))n≥0 counting the number of positive entries on each row. By introducing a convenient tree structure, we provide a recurrence relation for (S(n))n≥0. This leads to a connection with the 2-regular Stern–Brocot sequence and the sequence of denominators occurring in the Farey tree. Then we extend our construction to the Zeckendorf numeration system based on the Fibonacci sequence. Again our tree structure permits us to obtain recurrence relations for and the F-regularity of the corresponding sequence. [less ▲]

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See detailFluctuations of Attentional Networks and Default Mode Network during the Resting State Reflect Variations in Cognitive States: Evidence from a Novel Resting-state
Van Calster, Laurens ULg; D'Argembeau, Arnaud ULg; SALMON, Eric ULg et al

in Journal of Cognitive Neuroscience (2017)

Neuroimaging studies have revealed the recruitment of a range of neural networks during the resting state, which might reflect a variety of cognitive experiences and processes occurring in an individual's ... [more ▼]

Neuroimaging studies have revealed the recruitment of a range of neural networks during the resting state, which might reflect a variety of cognitive experiences and processes occurring in an individual's mind. In this study, we focused on the default mode network (DMN) and attentional networks and investigated their association with distinct mental states when participants are not performing an explicit task. To investigate the range of possible cognitive experiences more directly, this study proposes a novel method of resting-state fMRI experience sampling, informed by a phenomenological investigation of the fluctuation of mental states during the resting state. We hypothesized that DMN activity would increase as a function of internal mentation and that the activity of dorsal and ventral networks would indicate states of top–down versus bottom–up attention at rest. Results showed that dorsal attention network activity fluctuated as a function of subjective reports of attentional control, providing evidence that activity of this network reflects the perceived recruitment of controlled attentional processes during spontaneous cognition. Activity of the DMN increased when participants reported to be in a subjective state of internal mentation, but not when they reported to be in a state of perception. This study provides direct evidence for a link between fluctuations of resting-state neural activity and fluctuations in specific cognitive processes. [less ▲]

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See detailDéficits de la conscience autonoétique et de la mémoire autobiographique: résultats d'une intervention cognitive dans la schizophrénie.
Boulanger, Marie ULg; Neumann, Aurore; Blairy, Sylvie ULg

in Pratiques Psychologiques (2017)

The study evaluates the effects of a cognitive intervention called Self-Awareness Therapy (SAT) on abilities of mental time travel in deficit in schizophrenia. Among whole schizophrenia participants ... [more ▼]

The study evaluates the effects of a cognitive intervention called Self-Awareness Therapy (SAT) on abilities of mental time travel in deficit in schizophrenia. Among whole schizophrenia participants, seven participated in SAT, four took part in the Integrative Program Therapy (IPT) and six followed a treatment as usual. Before and after interventions, participants were asked to complete TEMPau for autonoetic awareness and autobiographical memory such as TeMA, for autobiographical memory and projection into future events. Intragroups and individual statistical analyses were conducted. The participants of SAT intervention reported more specific past TEMPau and future specific events on TeMA after therapy. Results support that, in schizophrenia, the retrieving of past specific memories and projection into future specific events could be improved under certain conditions only. [less ▲]

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See detailAre Th17 Cells Playing a Role in Immunity to Dermatophytosis?
Heinen, Marie-Pierre ULg; Cambier, Ludivine ULg; Fievez, Laurence ULg et al

in Mycopathologia (2017), 182(1), 251-261

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See detailLegal Mobilization Within the Bureaucracy: Disability Rights and the Implementation of Antidiscrimination Law in Sweden
Lejeune, Aude ULg

in Law and Policy (2017)

This paper argues that the analysis of legal mobilization needs to give more attention to the state and its relationship with social movements in order to examine how the state either sustains social ... [more ▼]

This paper argues that the analysis of legal mobilization needs to give more attention to the state and its relationship with social movements in order to examine how the state either sustains social movements' demands or is a field of contention for those demands. Focusing on how disability bureaucrats and activists mobilize antidiscrimination law in Sweden, this article shows that two main factors shape legal mobilization within the bureaucracy and alter the state's ability to become a legal mobilization actor: (1) the institutional relationships between social movement organizations and government agencies; and (2) the profiles and careers of bureaucrats and activists. It concludes by suggesting several lines for further research on law and social movements in nonpluralist countries. [less ▲]

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See detailDo flower mixtures with high functional diversity enhance aphid predators in wildflower strips?
Hatt, Séverin ULg; Uyttenbroeck, Roel ULg; Chevalier Mendes Lopes, Thomas ULg et al

in European Journal of Entomology (2017), 114

Among semi-natural elements in agricultural landscapes, wildflower strips sown at field margins or within fields represent potential habitats for the natural enemies of insect pests. As insects are ... [more ▼]

Among semi-natural elements in agricultural landscapes, wildflower strips sown at field margins or within fields represent potential habitats for the natural enemies of insect pests. As insects are sensitive to a variety of flower traits, we hypothesised that mixtures with high functional diversity attract and support a higher abundance and species richness of aphid flower visiting predators compared to mixtures with low functional diversity. During a field experiment, repeated over two years (2014 and 2015) in Gembloux (Belgium), aphid predators (i.e., lacewings, ladybeetles and hoverflies) were pan-trapped in five sown flower mixtures (including a control mixture, with three replicates of each mixture) of low to high functional diversity based on seven traits (i.e., flower colour, ultra-violet reflectance and pattern, blooming start and duration, height and flower class, primarily based on corolla morphology). In both years, flower species in the sown mixtures (i.e., sown and spontaneous flowers) were listed, and the realised functional diversity of each plot was calculated. Over the two years, an increase in functional diversity did not result in an increase in the abundance and richness of aphid predators. Moreover, ladybeetles, representing the majority of trapped predators, were more abundant in mixtures with very low or intermediary functional diversity at sowing, especially in 2014. We hypothesise that certain flower species, which were abundant in certain mixtures (and not in those exhibiting the highest functional diversity), attracted predators and were sufficiently represented to support them. Our results present novel information that could be used to the development of flower mixtures that provide effective ecosystem services, such as pest control. [less ▲]

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See detailATLANTIC-FRUGIVORY: A PLANT-FRUGIVORE INTERACTION DATASET FOR THE ATLANTIC FOREST
Bello, C; Galetti, M; Montan, D et al

in Ecology (2017)

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See detailOutcomes of UCB transplantation are comparable in FLT3+ AML: Results of CIBMTR, eurocord and EBMT collaborative analysis.
Ustun, C.; Giannotti, F.; Zhang, M.-J. et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (2017)

Allogeneic hematopoietic cell transplantation (HCT) from siblings or unrelated donors (URD) during complete remission (CR) may improve leukemia-free survival (LFS) in FLT3+ acute myeloid leukemia (AML ... [more ▼]

Allogeneic hematopoietic cell transplantation (HCT) from siblings or unrelated donors (URD) during complete remission (CR) may improve leukemia-free survival (LFS) in FLT3+ acute myeloid leukemia (AML) that has poor prognosis due to high relapse rates. Umbilical cord blood (UCB) HCT outcomes are largely unknown in this population. We found that compared with sibling HCT, relapse risks were similar after UCB (n=126), (HR 0.86, P=0.54) and URD (n=91) (HR 0.81, P=0.43). UCB HCT was associated with statistically higher non-relapse mortality compared with sibling HCT (HR 2.32, P=0.02), but not vs URD (HR 1.72, P=0.07). All three cohorts had statistically not significant 3-year LFS: 39% (95% CI 30-47) after UCB, 43% (95% CI 30-54) after sibling, and 50% (95% CI 40-60) after URD. Chronic GVHD rates were significantly lower after UCB compared with either sibling (HR 0.59, P=0.03) or URD (HR 0.49, P=0.001). Adverse factors for LFS included high leukocyte count at diagnosis and HCT during CR2. UCB is a suitable option for adults with FLT3+AML in the absence of an HLA-matched sibling and its immediate availability may be particularly important for FLT3+ AML where early relapse is common thus allowing HCT in CR1 when outcomes are best.Leukemia accepted article preview online, 25 January 2017. doi:10.1038/leu.2017.42. [less ▲]

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See detailTracking the Subtle Mutations Driving Host Sensing by the Plant Pathogen Streptomyces scabies
Jourdan, Samuel; Francis, Jourdan; Deflandre, Benoit et al

in mSphere (2017)

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See detailImpact of pollen resources drift on common bumblebees in NW Europe
Roger, N.; Moerman, R.; Carvalheiro, L. G. et al

in Global Change Biology (2017), 23(1), 68-76

Several bee species are experiencing significant population declines. As bees exclusively rely on pollen for development and survival, such declines could be partly related to changes in their host plant ... [more ▼]

Several bee species are experiencing significant population declines. As bees exclusively rely on pollen for development and survival, such declines could be partly related to changes in their host plant abundance and quality. Here, we investigate whether generalist bumblebee species, with stable population trends over the past years, adapted their diets in response to changes in the distribution and chemical quality of their pollen resources. We selected five common species of bumblebee in NW Europe for which we had a precise description of their pollen diet through two time periods (‘prior to 1950’ and ‘2004–2005’). For each species, we assessed whether the shift in their pollen diet was related with the changes in the suitable area of their pollen resources. Concurrently, we evaluated whether the chemical composition of pollen resources changed over time and experimentally tested the impact of new major pollen species on the development of B. terrestris microcolonies. Only one species (i.e. B. lapidarius) significantly included more pollen from resources whose suitable area expanded. This opportunist pattern could partly explain the expansion of B. lapidarius in Europe. Regarding the temporal variation in the chemical composition of the pollen diet, total and essential amino acid contents did not differ significantly between the two time periods while we found significant differences among plant species. This result is driven by the great diversity of resources used by bumblebee species in both periods. Our bioassay revealed that the shift to new major pollen resources allowed microcolonies to develop, bringing new evidence on the opportunist feature of bumblebee in their diets. Overall, this study shows that the response to pollen resource drift varies among closely related pollinators, and a species-rich plant community ensures generalist species to select a nutrient-rich pollen diet. © 2016 John Wiley & Sons Ltd [less ▲]

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See detailTowards a chromatographic similarity index to establish localised Quantitative Structure-Retention Relationships for retention prediction. II Use of Tanimoto similarity index in ion chromatography
Park, S. H.; Talebi, M.; Amos, R. I. J. et al

in Journal of Chromatography. A (2017)

Quantitative Structure-Retention Relationships (QSRR) are used to predict retention times of compounds based only on their chemical structures encoded by molecular descriptors. The main concern in QSRR ... [more ▼]

Quantitative Structure-Retention Relationships (QSRR) are used to predict retention times of compounds based only on their chemical structures encoded by molecular descriptors. The main concern in QSRR modelling is to build models with high predictive power, allowing reliable retention prediction for the unknown compounds across the chromatographic space. With the aim of enhancing the prediction power of the models, in this work, our previously proposed QSRR modelling approach called "federation of local models" is extended in ion chromatography to predict retention times of unknown ions, where a local model for each target ion (unknown) is created using only structurally similar ions from the dataset. A Tanimoto similarity (TS) score was utilised as a measure of structural similarity and training sets were developed by including ions that were similar to the target ion, as defined by a threshold value. The prediction of retention parameters (a- and b-values) in the linear solvent strength (LSS) model in ion chromatography, log k = a - blog[eluent], allows the prediction of retention times under all eluent concentrations. The QSRR models for a- and b-values were developed by a genetic algorithm-partial least squares method using the retention data of inorganic and small organic anions and larger organic cations (molecular mass up to 507) on four Thermo Fisher Scientific columns (AS20, AS19, AS11HC and CS17). The corresponding predicted retention times were calculated by fitting the predicted a- and b-values of the models into the LSS model equation. The predicted retention times were also plotted against the experimental values to evaluate the goodness of fit and the predictive power of the models. The application of a TS threshold of 0.6 was found to successfully produce predictive and reliable QSRR models (Qext(F2) 2 >. 0.8 and Mean Absolute Error. <. 0.1), and hence accurate retention time predictions with an average Mean Absolute Error of 0.2. min. © 2017. [less ▲]

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See detailPersistence of the effec of frugivore identity on post-dispersal seed fate: consequences for the assessment of functional redundancy
Lugon, Ana Paula; Boutefeu, Marion; Bovy, Emilie et al

in Biotropica (2017)

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See detailIncreased expression of bacterial amoA during an N2O emission peak in an agricultural field
Theodorakopoulos, Nicolas ULg; Lognoul, Margaux ULg; Degrune, Florine ULg et al

in Agriculture, Ecosystems & Environment (2017), 236

Levels of N-cycle gene transcripts (nirK, nirS, nosZ, amoA) were measured during an N2O emission peak in an agricultural soil. Automated dynamic closed chambers were used to monitor an N2O emission peak ... [more ▼]

Levels of N-cycle gene transcripts (nirK, nirS, nosZ, amoA) were measured during an N2O emission peak in an agricultural soil. Automated dynamic closed chambers were used to monitor an N2O emission peak on a maize crop after a natural rainfall. The peak occurred rapidly after the rainfall began. Spatial and temporal variability in N2O emission was observed between chambers. An analysis of N-cycle gene transcript levels revealed an increase in bacterial amoA gene transcripts (but not in archaeal amoA transcripts), correlating strongly with N2O emission. This suggests the involvement of nitrification enzymes, despite a high water-filled pore space (80%). Reverse transcription of bacterial 16S rRNA followed by partial sequencing of the resulting cDNAs revealed few rainfall-induced changes in the potentially active bacterial community, and notably no significant change in the relative abundance of 16S rRNAs from the nitrifier genus Nitrosospira. Expression of the amoA gene appears as a possible proxy for monitoring the N2O emission peak. To our knowledge, this is the first experiment to evaluate the expression of N-cycle genes during an N2O emission peak on an agricultural field. [less ▲]

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See detailLa « discrimination à rebours » au sein du marché intérieur : une illégalité qu’il ne faut pas voir au niveau européen ?
Van Cleynenbreugel, Pieter ULg

in Revue de la Faculté de Droit de l'Université de Liège (2017)

Cet article dresse un panorama de la jurisprudence sur les situations purement internes au droit du marché intérieur et du phénomène juridique de la discrimination à rebours. Il est conclu qu'une telle ... [more ▼]

Cet article dresse un panorama de la jurisprudence sur les situations purement internes au droit du marché intérieur et du phénomène juridique de la discrimination à rebours. Il est conclu qu'une telle discrimination est inhérente au régime juridique de l'Union européenne caractérisé par le principe d'attribution des compétences. Il convient aux Etats membres d'y apporter des solutions fondées sur leurs droits constitutionnels respectifs. [less ▲]

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See detailTwo new species in the Micarea prasina group from Western Europe
van den Boom, Pieter P. G.; Brand, A. Maarten; Coppins, Brian J. et al

in Lichenologist (2017), 49(1), 13-25

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See detailA nonlinear state-space approach to hysteresis identification
Noël, Jean-Philippe ULg; Esfahani, Alireza; Kerschen, Gaëtan ULg et al

in Mechanical Systems & Signal Processing (2017), 84

Most studies tackling hysteresis identification in the technical literature follow white-box approaches, i.e. they rely on the assumption that measured data obey a specific hysteretic model. Such an ... [more ▼]

Most studies tackling hysteresis identification in the technical literature follow white-box approaches, i.e. they rely on the assumption that measured data obey a specific hysteretic model. Such an assumption may be a hard requirement to handle in real applications, since hysteresis is a highly individualistic nonlinear behaviour. The present paper adopts a black-box approach based on nonlinear state-space models to identify hysteresis dynamics. This approach is shown to provide a general framework to hysteresis identification, featuring flexibility and parsimony of representation. Nonlinear model terms are constructed as a multivariate polynomial in the state variables, and parameter estimation is performed by minimising weighted least-squares cost functions. Technical issues, including the selection of the model order and the polynomial degree, are discussed, and model validation is achieved in both broadband and sine conditions. The study is carried out numerically by exploiting synthetic data generated via the Bouc-Wen equations. [less ▲]

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See detailThe neural bases of proactive and reactive control processes in normal aging
Manard, Marine ULg; François, Sarah ULg; Phillips, Christophe ULg et al

in Behavioural Brain Research (2017), 320

Introduction. Research on cognitive control suggests an age-related decline in proactive control abilities (anticipatory control), whereas reactive control (following conflict detection) seems to remain ... [more ▼]

Introduction. Research on cognitive control suggests an age-related decline in proactive control abilities (anticipatory control), whereas reactive control (following conflict detection) seems to remain intact. As proactive and reactive control abilities are associated with specific brain networks, this study investigated age-related effects on the neural substrates associated with each kind of control. Methods. In an event-related fMRI study, a modified version of the Stroop task was administered to groups of 20 young and 20 older healthy adults. Based on the theory of dual mechanisms of control, the Stroop task has been built to induce proactive or reactive control depending on task context. Results. Behavioral results (p < .05) indicated faster processing of interfering items in the mostly incongruent (MI) than the mostly congruent (MC) context in both young and older participants. fMRI results showed that reactive control is associated with increased activity in left frontal areas for older participants. For proactive control, decreased activity in the bilateral anterior cingulate cortex was associated with more activity in the right middle frontal gyrus in the older than the younger group. Conclusion. These observations support the hypothesis that aging affects the neural networks associated with reactive and proactive cognitive control differentially. These age-related changes are very similar to those observed in young adults with low dopamine availability, suggesting that a general mechanism (prefrontal dopamine availability) may modulate brain networks associated with various kinds of cognitive control. [less ▲]

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See detailUse of donor milk in the neonatal intensive care unit
de halleux, Virginie; Pieltain, Catherine; SENTERRE, Thibault ULg et al

in Seminars in Fetal & Neonatal Medicine (2017)

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See detailA multivariable prediction model for pegvisomant dosing: monotherapy and in combination with long-acting somatostatin analogues
Franck, Sanne Elisabeth; Korevaar, Tim; PETROSSIANS, Patrick ULg et al

in European Journal of Endocrinology (2017)

Background: Effective treatment of acromegaly with pegvisomant (PEGV), a growth hormone receptor antagonist, requires an appropriate dose titration. PEGV doses vary widely among individual patients, and ... [more ▼]

Background: Effective treatment of acromegaly with pegvisomant (PEGV), a growth hormone receptor antagonist, requires an appropriate dose titration. PEGV doses vary widely among individual patients, and various covariates may affect its dosing and pharmacokinetics. Objective: To identify predictors of the PEGV dose required to normalize insulin-like growth factor I (IGF-I) levels during PEGV monotherapy and in combination with long-acting somatostatin analogues (LA-SSAs). 188) were meta-analysed as a form of external replication to study the predictors of PEGV dosing in addition to LA-SSA, the LAS (n=83) was used to study the predictors of PEGV monotherapy dosing. Multivariable regression models were used to identify predictors of the PEGV dose required to normalize IGF-I levels. <0.001, p=<0.001, p=0.028 and p=0.047, respectively). Taken together, these characteristics predicted the PEGV normalization dose correctly in 63.3% of all patients within a range of +/- 60 mg/week (21.3% within a range of +/- 20 mg/week). For monotherapy, only weight was associated with the PEGV normalization dose (p=<0.001) and predicted this dosage correctly in 77.1% of all patients within a range of +/- 60 mg/week (31.3% within a range of +/- 20 mg/week). Conclusion: In this study, we show that IGF-I levels, weight, height and age can contribute to define the optimal PEGV dose in order to normalize IGF-I levels in addition to LA-SSA. For PEGV monotherapy, only the patient's weight was associated with the IGF-I normalization PEGV dosage. [less ▲]

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See detailSartre, le XXe siècle
Cormann, Grégory ULg

in Médium (2017), 50

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See detailDesign sensitivity analysis for shape optimization based on the Lie derivative
Kuci, Erin ULg; Henrotte, François ULg; Duysinx, Pierre ULg et al

in Computer Methods in Applied Mechanics & Engineering (2017)

Abstract The paper presents a theoretical framework for the shape sensitivity analysis of systems governed by partial differential equations. The proposed approach, based on geometrical concepts borrowed ... [more ▼]

Abstract The paper presents a theoretical framework for the shape sensitivity analysis of systems governed by partial differential equations. The proposed approach, based on geometrical concepts borrowed from differential geometry, shows that sensitivity of a performance function (i.e. any function of the solution of the problem) with respect to a given design variable can be represented mathematically as a Lie derivative, i.e. the derivative of that performance function along a flow representing the continuous shape modification of the geometrical model induced by the variation of the considered design variable. Theoretical formulae to express sensitivity analytically are demonstrated in detail in the paper, and applied to a nonlinear magnetostatic and a linear elastic problem, following both the direct and the adjoint approaches. Following the analytical approach, one linear system of which only the right-hand side needs be evaluated (the system matrix being known already) has to be solved for each of the design variables in the direct approach, or for each performance functions in the adjoint approach. A substantial gain in computation time is obtained this way compared to a finite difference evaluation of sensitivity, which requires solving a second nonlinear system for each design variable. This is the main motivation of the analytical approach. There is some freedom in the definition of the auxiliary flow that represents the shape modification. We present a method that makes benefit of this freedom to express sensitivity locally as a volume integral over a single layer of finite elements connected to both sides of the surfaces undergoing shape modification. All sensitivity calculations are checked with a finite difference in order to validate the analytic approach. Convergence is analyzed in 2D and 3D, with first and second order finite elements. [less ▲]

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See detailSedimentologic and paleoclimatic reconstructions of carbonate factory evolution in the Alborz Basin (northern Iran) indicate a global response to Early Carboniferous (Tournaisian) glaciations
Sardar Abadi, Mehrdad; Kulagina, E.; Voeten, D.F.A.E. et al

in Sedimentary Geology (2017), 348

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See detailL'image de marque des villes wallonnes
Scatton, Loïc; Schmitz, Serge ULg

in Belgeo (2017), 2016(1),

City branding practices have become widespread but few studies measure their effects on medium-sized cities. Through an analysis of the practices of city branding and internal and external images of the ... [more ▼]

City branding practices have become widespread but few studies measure their effects on medium-sized cities. Through an analysis of the practices of city branding and internal and external images of the cities of Liege and Charleroi, this article points out the relative strengths and weaknesses of the images of each of the Walloon cities, among their businessmen, vis-a vis those of the other Walloon city. The images of these two cities are composites and branding policies are still in their infancy. These policies have followed a top-down approach which may explain the limited use of the two brands even if they use ideas shared by local entrepreneurs. However the research underlines the absence of opinions on certain characteristics of the cities or a negative view which often requires works in the field but also better communication. [less ▲]

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See detailLa « personnalité antisociale », antithèse de la psychopathologie
Englebert, Jérôme ULg; Adam, Christophe

in Déviance et Société (2017), 41(1), 3-28

L’article propose une réflexion critique et clinique sur la notion de « personnalité antisociale », largement usitée dans le domaine de la nosographie des troubles mentaux et des pratiques « psy- » au ... [more ▼]

L’article propose une réflexion critique et clinique sur la notion de « personnalité antisociale », largement usitée dans le domaine de la nosographie des troubles mentaux et des pratiques « psy- » au sein du système de justice pénale. Notre réflexion débutera par une généalogie du vocable dans différentes versions de la classification psychiatrique, depuis les années cinquante jusqu’aujourd’hui, et plus particulièrement celle faisant autorité du Manuel statistique et diagnostique des troubles mentaux (DSM). L’absence de raisonnement sociologique dans l’usage d’une notion impliquant pourtant la référence au « social » sera discutée ainsi que ses évolutions historiques. Ensuite, la démonstration de l’antithèse que cette notion constitue pour une perspective psychopathologique digne de ce nom – dynamique, compréhensive et phénoménologique – sera développée en six arguments majeurs et plurivoques, tantôt empiriques et cliniques, tantôt théoriques. [less ▲]

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See detailL’indemnité de procédure, l’appel de la partie civile et l’acquittement du prévenu : la croix et la bannière ?
Michiels, Olivier ULg; Falque, Géraldine ULg

in Revue de Droit Pénal et de Criminologie (2017), 2017/1

En ce qu’il ne permet pas au juge répressif d’accorder au prévenu acquitté et au civilement responsable une indemnité de procédure d’appel à charge de la partie civile succombante qui, en l’absence de ... [more ▼]

En ce qu’il ne permet pas au juge répressif d’accorder au prévenu acquitté et au civilement responsable une indemnité de procédure d’appel à charge de la partie civile succombante qui, en l’absence de tout recours du ministère public, a interjeté appel d’un jugement d’acquittement statuant sur une action intentée par le ministère public, l’article 162bis, alinéa 2, du Code d’instruction criminelle viole les articles 10 et 11 de la Constitution. [less ▲]

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See detailThermal Conductivity of Straw Bales: Full Size Measurements Considering the Direction of the Heat Flow
Costes, Jean-Philippe; Evrard, Arnaud; Biot, Benjamin et al

in Buildings (2017), 7(11), 1-15

The thermal conductivity of straw bales is an intensively discussed topic in the international straw bale community. Straw bales are, by nature, highly heterogeneous and porous. They can have a relatively ... [more ▼]

The thermal conductivity of straw bales is an intensively discussed topic in the international straw bale community. Straw bales are, by nature, highly heterogeneous and porous. They can have a relatively large range of density and the baling process can influence the way the fibres are organised within the bale. In addition, straw bales have a larger thickness than most of the insulating materials that can be found in the building industry. Measurement apparatus is usually not designed for such thicknesses, and most of the thermal conductivity values that can be found in the literature are defined based on samples in which the straw bales are resized. During this operation, the orientation of the fibres and the density may not be preserved. This paper starts with a literature review of straw bale thermal conductivity measurements and presents a measuring campaign performed with a specific Guarded Hot Plate, designed to measure samples up to 50 cm thick. The influence of the density is discussed thoroughly. Representative values are proposed for a large range of straw bales to support straw-bale development in the building industry. [less ▲]

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See detailAssessment of corrosion resistance, material properties, and weldability of alloyed steel for ballast tanks
De Baere, Kris; Verstraelen, Helen; Willemen, Remke et al

in Journal of Marine Science & Technology (2017), 22(1), 176-199

Ballast tanks are of great importance in the lifetime of modern merchant ships. Making a ballast tank less susceptible to corrosion can, therefore, prolong the useful life of a ship and, thereby, lower ... [more ▼]

Ballast tanks are of great importance in the lifetime of modern merchant ships. Making a ballast tank less susceptible to corrosion can, therefore, prolong the useful life of a ship and, thereby, lower its operational cost. An option to reinforce a ballast tank is to construct it out of a corrosion-resistant steel type. Such steel was recently produced by POSCO Ltd., South Korea. After 6 months of permanent immersion, the average corrosion rate of A and AH steel (31 samples) was 535 g m−2 year−1, while the Korean CRS was corroding with 378 g m−2 year−1. This entails a gain of 29 %. Follow-up measurements after 10, 20, and 24 months confirmed this. The results after 6 months exposure to alternating wet/dry conditions are even more explicit. Furthermore, the physical and metallurgical properties of this steel show a density of 7.646 t/m3, the elasticity modulus 209.3 GPa, the tensile strength 572 MPa, and the hardness 169HV10. Microscopically, the metal consists of equiaxed and recrystallized grains (ferrite and pearlite), with an average size of between 20 and 30 µm (ASTM E 112—12 grain size number between 7 and 8) with a few elongated pearlitic grains. The structure is banded ferrite/pearlite. On the basis of a series of energy dispersive X-ray spectrometer measurements the lower corrosion rate of the steel can be attributed to the interplay of Al, Cr, their oxides, and the corroding steel. In addition, the role of each element in the formation of oxide layers and the mechanisms contributing to the corrosion resistance are discussed. [less ▲]

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See detailExploring the effects of seismicity on landslides and catchment sediment yield: An Italian case study
Vanmaercke, Matthias ULg; Ardizzone, F.; Rossi, M. et al

in Geomorphology (2017), 278

Recent studies showed that contemporary average catchment sediment yields (SY, [t km− 2 y− 1]) at regional and continental scales are often strongly correlated to spatial patterns of seismic activity ... [more ▼]

Recent studies showed that contemporary average catchment sediment yields (SY, [t km− 2 y− 1]) at regional and continental scales are often strongly correlated to spatial patterns of seismic activity. Nonetheless, we currently have little insights into the mechanisms that explain these correlations. We investigated how spatial patterns of SY in Italy are linked to patterns of seismic activity. For a dataset of 103 Italian catchments with average SY measured over a period of years to decades, we extracted tectonic and none-tectonic variables that potentially explain observed differences in SY. These include proxies for vertical uplift rates and cumulative seismic moments (CSM) associated with historic earthquakes of different ranges of magnitude. Results showed that also across Italy, SY is significantly correlated to seismicity. However, SY showed much stronger correlations with proxies of seismicity relating to small but frequent earthquakes (2 ≤ Mw < 4) than with proxies relating to tectonic uplift or large, potentially landslide-triggering earthquakes (Mw ≥ 4). Analyses of a dataset of about 500,000 landslides across Italy showed very comparable trends: spatial patterns of landslides within similar lithological units generally show a significant positive correlation with CSM of weak but frequent seismicity and generally not with CSM of large earthquakes. These results suggest that, on a decadal time scale and at a regional/continental spatial scale, frequent but relatively weak seismicity may exert a more important geomorphic impact than large earthquake events or tectonic uplift. © 2016 Elsevier B.V. [less ▲]

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See detailCorn stover as feedstock for the production of ethanol: chemical composition of different anatomical fractions and varieties
Berchem, Thomas ULg; Roiseux, Olivier; Vanderghem, Caroline et al

in Biofuels, Bioproducts and Biorefining (2017)

The available grain corn stover produced in Belgium is estimated at 290 000 dry tons, a suffi cient amount to supply a biorefi nery. Differences regarding size, prematurity, and drying speed have been ... [more ▼]

The available grain corn stover produced in Belgium is estimated at 290 000 dry tons, a suffi cient amount to supply a biorefi nery. Differences regarding size, prematurity, and drying speed have been observed among the cultivated grain corn varieties in Wallonia (Belgium). This study aims to evaluate the variation in composition of different anatomical fractions (stalks, leaves, cobs, and husks) of three Walloon varieties of grain corn stover (SyMultitop, Padrino, and Alduna) with significant production volumes. In addition, the Padrino variety was assessed for variation in chemical composition at three harvesting times. Walloon grain corn stover contains large amounts of polysaccharides (33.4% to 41.3% of glucans and 13.9% to 28.2% of xylans) and lignin (10.4% to 15.3%). Some différences were noted between varieties and anatomical fractions. Depending on how the feedstock is harvested, it is possible to produce between 79 and 81 M liters of ethanol per year without adversely affecting soil sustainability. [less ▲]

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See detailEmission and oxidation of methane in a meromictic, eutrophic and temperate lake (Dendre, Belgium)
Roland, Fleur ULg; Darchambeau, François ULg; Morana, Cédric ULg et al

in Chemosphere (2017)

We sampled the water column of the Dendre stone pit lake (Belgium) in spring, summer, autumn and winter. Depth profiles of several physico-chemical variables, nutrients, dissolved gases (CO2, CH4, N2O ... [more ▼]

We sampled the water column of the Dendre stone pit lake (Belgium) in spring, summer, autumn and winter. Depth profiles of several physico-chemical variables, nutrients, dissolved gases (CO2, CH4, N2O), sulfate, sulfide, iron and manganese concentrations and d13C-CH4 were determined. We performed incubation experiments to quantify CH4 oxidation rates, with a focus on anaerobic CH4 oxidation (AOM), without and with an inhibitor of sulfate reduction (molybdate). The evolution of nitrate and sulfate concentrations during the incubations was monitored. The water column was anoxic below 20 m throughout the year, and was thermally stratified in summer and autumn. High partial pressure of CO2 and CH4 and high concentrations of ammonium and phosphate were observed in anoxic waters. Important nitrous oxide and nitrate concentration maxima were also observed (up to 440 nmol L- 1 and 80 mmol L -1, respectively). Vertical profiles of d13C-CH4 unambiguously showed the occurrence of AOM. Important AOM rates (up to 14 mmol L -1 d- 1) were observed and often co-occurred with nitrate consumption peaks, suggesting the occurrence of AOM coupled with nitrate reduction. AOM coupled with sulfate reduction also occurred, since AOM rates tended to be lower when molybdate was added. CH4 oxidation was mostly aerobic (~80% of total oxidation) in spring and winter, and almost exclusively anaerobic in summer and autumn. Despite important CH4 oxidation rates, the estimated CH4 fluxes from the water surface to the atmosphere were high (mean of 732 mmol m- 2 d- 1 in spring, summer and autumn, and up to 12,482 mmol m- 2 d- 1 in winter). [less ▲]

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See detailAdresse, opinion et responsabilité : un modèle de la subjectivation en public
Servais, Christine ULg

in Questions de Communication (2017)

Cet article interroge la relation entre « publics » et « collectifs » et en propose un modèle de description à caractère phénoménologique. Après un examen des implications politiques des modèles auxquels ... [more ▼]

Cet article interroge la relation entre « publics » et « collectifs » et en propose un modèle de description à caractère phénoménologique. Après un examen des implications politiques des modèles auxquels sont susceptibles de se référer les théories de la réception médiatique, on tente d’élaborer, à partir du travail de Stiegler, de Rancière et de Derrida, une approche de la réception qui permet de décrire à la fois l’émancipation et la domination, cette alternative étant l’un des points de butée des théories de la réception. Le critère déterminant est ici l’adresse, considérée comme la traduction en termes phénoménologiques de l’énonciation. La réception est alors envisagée comme une réponse à une adresse. Cette conception de l’énonciation rend compte de la dimension politique d’une réception médiatique où l’identité sociale est désormais indexée sur notre identité de destinataires de dispositifs médiatique, c’est-à-dire de publics [less ▲]

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See detailDon't judge a fish by its fins: species delineation of Congolese Labeo (Cyprinidae)
Van Steenberge, Maarten; Gajdzik, Laura ULg; Chilala, Alex et al

in Zoologica Scripta (2016)

Conspicuous characters are often useful in species identification. Yet, identification and delineation are two different processes, and such characters do not necessarily provide the best basis on which ... [more ▼]

Conspicuous characters are often useful in species identification. Yet, identification and delineation are two different processes, and such characters do not necessarily provide the best basis on which species can be delineated. This is illustrated by the case of the Labeo with papillary lips from the Congo basin. Traditionally, species delineation in this group was based on a conspicuous trait: the shape of the dorsal fin, which shows a profound degree of differentiation. Morphometric analyses were performed on 185 specimens both with and without measurements taken on this fin. The groups obtained using these two approaches were compared with those obtained through DNA barcoding. For this, 24 sequences of the standard barcoding COI gene were obtained. Species delineations based on morphological and molecular results were in agreement when the shape of the dorsal fin was ignored. This suggested that of the five nominal species known from the Congo basin, L. altivelis, L. rosae, L. lineatus, L. weeksii and L. maleboensis, only the former three remain valid. Consequently, L. weeksii was synonymised with L. altivelis and L. maleboensis with L. lineatus. The sole Congo basin endemic is L. lineatus as L. altivelis and L. rosae also occur in more southern basins. The use of the shape of the dorsal fin in morphological studies has previously led to overestimates of species diversity in this group. This is due to the fact that L. altivelis shows a remarkable amount of geographical variation for this trait. The large amount of intra- and interspecific variation in this character was caused by differential allometric growth in different parts of the dorsal fin. [less ▲]

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See detailIs Competence a Holy Grail for Teaching? Reflections on Nursing Education
Dancot, Jacinthe ULg

in Nursing & Care Open Access Journal (2016), 1(4), 00021

The competence-based approach is largely widespread in the nursing schools and is viewed as a golden standard for professional teaching. But the practical use of the concept is varying among institutions ... [more ▼]

The competence-based approach is largely widespread in the nursing schools and is viewed as a golden standard for professional teaching. But the practical use of the concept is varying among institutions and even teachers. The goal of this narrative review is to clarify the conception of competence and its use in the fields of education and nursing. Regarding education, Gonczi, Tardif, Jonnaert and Beckers are the key authors referred to. A first apparent consensus over the holistic nature of the competence quickly gives place to the observation of important nuances in conceptions. Similarly, in the field of nursing, Benner is first discussed, and recent literature reviews and concept analyses are taken into account: similar nuances are detected, as well as difficulties in the practical implementation of the concept. Considering the lack of consensus and the paradigmaticalincoherences detected among the sources consulted for this review, we question the use of competence as single point of view for teaching and assessing, and we propose other avenues to be explored in order to recognize emergent professionality. [less ▲]

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See detailContinuous Production of Itraconazole-based Solid Dispersions by Hot Melt Extrusion: Preformulation, Optimization and Design Space Determination.
Thiry, Justine ULg; Lebrun, Pierre; Vinassa, Chloé et al

in International Journal of Pharmaceutics (2016), 515(1-2), 114-124

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See detailComprehension of an organosolv process for lignin extraction on Festuca arundinacea and monitoring of the cellulose degradation
Schmetz, Quentin ULg; Maniet, Guillaume ULg; Jacquet, Nicolas ULg et al

in Industrial Crops and Products (2016), 94

It is commonly accepted that the current society needs to partially substitute fossil resources by renewable ones. Among many solutions, one approach consists in the development of biorefinery involving ... [more ▼]

It is commonly accepted that the current society needs to partially substitute fossil resources by renewable ones. Among many solutions, one approach consists in the development of biorefinery involving lignocellulosic biomass to produce bio-based materials and fuels. This study focuses on the comprehension of an organosolv treatment designed to break the complex lignocellulosic structure for high purity lignin extraction from tall fescue (Festuca arundinacea Schreb.). This grass benefits from an increasing interest in Western Europe and has been suggested as feedstock for biorefinery. However, its use as material for high purity lignin production has not been determined yet. Ethanol/water, 92/8% [v/v] with H2SO4 0.32 M was investigated at pilot scale under conventional heating (5 °C min−1 during 30 min and stabilized at 148 °C for 5 min). Precipitated lignin were analyzed as well as the composition of side-stream products (recovered cellulosic pulp and the aqueous hydrolysate). Lignin has been recovered at a purity level of 90% with a yield of 60%. The main contaminants were nitrogen containing compounds and degraded hemicelluloses. 2D-HSQC NMR (Two Dimension-Heteronuclear Single Quantum Correlation Nuclear Magnetic Resonance) revealed a co-extraction of ferulates and coumarates function as well as arabinoxylan. Cellulose was recovered at 53% purity with 60% yield. The conditions appear to be too harsh for tall fescue and led to significant amount of cellulose degradation. A process using a lower alcohol concentration will be developed to provide better yields of both cellulose and lignin. [less ▲]

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