References of "Scientific journals"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 601 to 700 of 54792     2 3 4 5 6 7 8 9 10 11 12     Populatieonderzoek naar de Hazelmuis in de VoerstreekVerbeylen, Goedele; Mouton, Alice ; Driessens, Gerald et alin De Levende Natuur (2016), (numero 1), The Hazel dormouse (Muscardinus avellanarius) is a habitat specialist that prefers dense shrub and tree vegetation and needs a high diversity of food plants on a limited area. Due to habitat degradation ... [more ▼]The Hazel dormouse (Muscardinus avellanarius) is a habitat specialist that prefers dense shrub and tree vegetation and needs a high diversity of food plants on a limited area. Due to habitat degradation and fragmentation the Flemish distribution area of this critically endangered species has been reduced to the eastern part of the municipality of Voeren, where it forms a cross-border population with the Dutch Hazel dormice. Since 2003 the Mammal Working Group of Natuurpunt studies the remaining Flemish population to find out more about population parameters, habitat use, the influence of habitat quality and management actions. In 2007 a standardised monitoring started by counting autumnal nests along fixed transects. In 2013 an intensive capture-mark-recapture study was set up based on nest box and nest tube checks and live-trapping on custom made hanging platforms; also a first test with radiocollars took place. The information gathered from the combination of all these methods will be used to validate the monitoring method and to formulate better protection measures. First results show that late summer and autumn should not be considered as the main reproduction period, at least not in an early year like 2014 when first young were already born at the beginning of May. Hazel dormice do not only cross significant barriers like the railway during dispersal, but also do this regularly during their nightly movements within their home range. Expansion of the population on a location with sufficient connectivity seems to be hampered by a too low population density resulting from insufficient habitat quality and (in this case) a high predation pressure by house cats. On the scale of the Meuse-Rhine Euregion, genetic analyses carried out by the University of Liège reveal four genetically isolated clusters, for which a vision to interconnect these was computed in the Interreg-project ‘Habitat Euregio’. [less ▲]Detailed reference viewed: 16 (0 ULg) Cost-effectiveness of personalized supplementation with vitamin D-rich dairy products in the prevention of osteoporotic fracturesEthgen, Olivier ; Hiligsmann, Mickaël; Burlet, Nansa et alin Osteoporosis International (2016), 27Summary: Titrated supplementations with vitamin D-fortified yogurt, based on spontaneous calcium and vitamin D intakes, can be cost-effective in postmenopausal women with or without increased risk of ... [more ▼]Summary: Titrated supplementations with vitamin D-fortified yogurt, based on spontaneous calcium and vitamin D intakes, can be cost-effective in postmenopausal women with or without increased risk of osteoporotic fractures. Introduction: The objective of this study is to assess the costeffectiveness of the vitamin D-fortified yogurt given to women with and without an increased risk of osteoporotic fracture. Methods: Avalidated cost-effectiveness microsimulation Markov model of osteoporosis management was used. Three personalized supplementation scenarios to reflect the Ca/Vit D needs taking into account the well-known variations in dietary habits and a possible pharmacological supplementation in Ca/ Vit D, given above or in combination with anti-osteoporosis medications: one yogurt per day, i.e., 400 mg of Ca+200 IU of Vit D (scenario 1 U), two yogurts per day, i.e., 800 mg of Ca+ 400 IU of Vit D (scenario 2 U), or three yogurts per day, i.e., 1, 200 mg of Ca+600 IU of Vit D (scenario 3 U). Results: One yogurt is cost-effective in the general population above the age of 70 years and in all age groups in women with low bone mineral density (BMD) or prevalent vertebral fracture (PVF). The daily intake of two yogurts is cost-effective above 80 years in the general population and above 70 years in the two groups of women at increased risk of fractures. However, an intake of three yogurts per day is only cost-effective above 80 years old in the general population, as well as in women with low BMD or PVF. Conclusions: Our study is the first economic analysis supporting the cost-effectiveness of dairy products, fortified with vitamin D, in the armamentarium against osteoporotic fractures. [less ▲]Detailed reference viewed: 17 (6 ULg) Genetic diversity and population structure of the Eurosian otte (Lutra lutra) in FranceGeboes, Anne-Laure ; Rosoux, René; Lemarchand, Charles et alin Mammal Research (2016), 61(1), During the last century, the Eurasian otter (Lutra lutra) suffered a dramatic decline in Europe. In France, the same pattern of sharp decline was observed with local extinctions in many regions. Before ... [more ▼]During the last century, the Eurasian otter (Lutra lutra) suffered a dramatic decline in Europe. In France, the same pattern of sharp decline was observed with local extinctions in many regions. Before the recolonisation process, two main populations still remained along the Atlantic coast and in the Massif Central. To investigate the impact of this decline on the genetic diversity and structure of the French otter population, tissue samples of 144 otter carcasses from road kills that were found during 1992–2011 along the Atlantic coast and in the Massif Central were used. They were analysed using 10 microsatellites loci. Observed (Ho = 0.64) and expected heterozygosity (He = 0.62) were moderate, but consistent with results found in other European populations. The bottleneck test showed an excess of heterozygotes, providing evidence of a recent decline. There was evidence for weak but significant allelic frequencies divergence between otters from the Atlantic coast and those from the Massif Central (Fst=0.040, p<0.05), probably resulting from their isolation prior to the recolonisation process. As the French otter population has been expanding for several years, genetic intermixing is now occurring. Although this expansion has not yet genetically homogenised all populations, this is may be a matter a time. [less ▲]Detailed reference viewed: 43 (12 ULg) Statistical analysis and multi-instrument overview of the quasi-periodic 1-hour pulsations in Saturn's outer magnetospherePalmaerts, Benjamin ; Roussos, E.; Krupp, N. et alin Icarus (2016), 271Detailed reference viewed: 17 (6 ULg) Dynamical thermalization in Bose-Hubbard systemsSchlagheck, Peter ; Shepelyansky, Dima L.in Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2016), 93We numerically study a Bose-Hubbard ring of finite size with disorder containing a finite number of bosons that are subject to an on-site two-body interaction. Our results show that moderate interactions ... [more ▼]We numerically study a Bose-Hubbard ring of finite size with disorder containing a finite number of bosons that are subject to an on-site two-body interaction. Our results show that moderate interactions induce dynamical thermalization in this isolated system. In this regime the individual many-body eigenstates are well described by the standard thermal Bose-Einstein distribution for well-defined values of the temperature and the chemical potential, which depend on the eigenstate under consideration. We show that the dynamical thermalization conjecture works well at both positive and negative temperatures. The relations to quantum chaos, quantum ergodicity, and the Åberg criterion are also discussed. [less ▲]Detailed reference viewed: 7 (0 ULg) Etude de cas: l'attentat au Musée juif de BruxellesDebras, François in Politique : Revue de Débats (2016), 93L’attaque soudaine d’un homme qui fait irruption dans un lieu public et tue quatre individus est angoissante. Les catastrophes, les drames et les malheurs qui frappent la société sont porteurs de ... [more ▼]L’attaque soudaine d’un homme qui fait irruption dans un lieu public et tue quatre individus est angoissante. Les catastrophes, les drames et les malheurs qui frappent la société sont porteurs de nombreuses questions : qui, comment, pourquoi, dans quel but,… ? Les théories du complot permettent de répondre à un besoin social, celui de comprendre. Le complot est d’autant plus attirant et convaincant qu’il apporte une réponse simple, globale et dépouillée de toute subtilité. [less ▲]Detailed reference viewed: 70 (18 ULg) Pre-employement examination for low back risk in workers exposesd to manual handling of loads : French guidelinesPETIT, Audrey; ROUSSEAU, Sandrine; HUEZ, Jean-François et alin International Archives of Occupational and Environmental Health (2016), 89Detailed reference viewed: 31 (1 ULg) Nos différences, une richesseRADERMECKER, Régis in Revue de l'Association Belge du Diabète (2016), 59Detailed reference viewed: 5 (0 ULg) LE CAS CLINIQUE DU MOIS Thrombose veineuse ovarienne gauche et extension à la veine rénaleJEAN, FLORENCE; CLAUDOT, A.; ISTACE, B. et alin Revue Médicale de Liège (2016), 71(1), 17-21Ovarian vein thrombosis is a rare, but potentially serious postpartum complication. In 80 % of the cases, it occurs on the right side and in less than 6 % on the left side; it is bilateral in 14 % of ... [more ▼]Ovarian vein thrombosis is a rare, but potentially serious postpartum complication. In 80 % of the cases, it occurs on the right side and in less than 6 % on the left side; it is bilateral in 14 % of cases. The usual clinical features include abdominal pain, fever and leucocytosis. However, the diagnosis is often complicated by other non specific signs and symptoms. Ovarian vein thrombosis may cause sepsis, pulmonary thromboembolism, and thrombosis of the inferior vena cava and the renal vein. The diagnosis can be established by CT scan or nuclear magnetic resonance imaging, which has a high sensitivity and specificity. Treatment for the ovarian vein thrombosis includes antibiotics and anticoagulation. The complications can sometimes be surgically managed. Prompt diagnosis and treatment can decrease the morbidity and the mortality. Nowadays, the fatal issue is rare as the appropriate treatment is quickly instaured. [less ▲]Detailed reference viewed: 23 (3 ULg) An Economic Appraisal of MOOC Platforms: Business Models and Impacts on Higher EducationJacqmin, Julien ; belleflamme, paulin CESifo Economic Studies (2016), 62(1), 148-169We use various economic and pedagogical concepts to understand the specificities of MOOC (Massive Online Open Courses) platforms. We discuss how the private provision of MOOCs can be sustained. Using the ... [more ▼]We use various economic and pedagogical concepts to understand the specificities of MOOC (Massive Online Open Courses) platforms. We discuss how the private provision of MOOCs can be sustained. Using the theory of multisided platforms, we analyze five ways to monetize the MOOC business. We then claim that MOOC platforms can play a key transformative role in the higher education sector by making teaching practices evolve, rather than by replacing incumbent institutions. Finally, we derive a number of directions for public policy [less ▲]Detailed reference viewed: 38 (3 ULg) Effect of coil orientation on strength-duration time constant and I-wave activation with controllable pulse parameter transcranial magnetic stimulationD'Ostilio, Kevin ; Goetz, Stefan; Hannah, Ricci et alin Clinical Neurophysiology (2016), 1Objective: To compare the strength-duration (S-D) time constants of motor cortex structures activated by current pulses oriented posterior-anterior (PA) or anterior-posterior (AP) across the central ... [more ▼]Objective: To compare the strength-duration (S-D) time constants of motor cortex structures activated by current pulses oriented posterior-anterior (PA) or anterior-posterior (AP) across the central sulcus. Methods: Motor threshold and input–output curve, along with motor evoked potential (MEP) latencies, of first dorsal interosseus were determined at pulse widths of 30, 60, and 120 μs using a controllable pulse parameter (cTMS) device, with the coil oriented PA or AP. These were used to estimate the S-D time constant and we compared with data for responses evoked by cTMS of the ulnar nerve at the elbow. Results: The S-D time constant with PA was shorter than for AP stimulation (230.9 ± 97.2 vs. 294.2 ± 90.9 us; p<0.001). These values were similar to those calculated after stimulation of ulnar nerve (197 ± 47us). MEP latencies to AP, but not PA stimulation were affected by pulse width, showing longer latencies following short duration stimuli. Conclusion: PA and AP stimuli appear to activate the axons of neurons with different time constants. Short duration AP pulses are more selective than longer pulses in recruiting longer latency corticospinal output. [less ▲]Detailed reference viewed: 42 (3 ULg) Characterizing the morphology of suburban settlements: a method based on a semi-automatic classification of building clustersde Smet, Fabian; Teller, Jacques in Landscape Research (2016), 41(1), 113-130Urban sprawl is transforming our landscapes and rural areas at a spectacular pace. Measuring the strength of the phenomenon and proposing dynamic ways to delineate suburban areas have been the object of ... [more ▼]Urban sprawl is transforming our landscapes and rural areas at a spectacular pace. Measuring the strength of the phenomenon and proposing dynamic ways to delineate suburban areas have been the object of much debate amongst scientists. The present article takes the view that, beyond measuring and delineating suburban areas, more efforts should be directed to qualifying the morphology of built settlements within these areas. Therefore it proposes a method based on a semi-automatic classification system of building clusters, designed to describe and interpret the phenomenon from a morphological perspective. This method is based on a combination of field surveys with numerical analyses of digital land cadastre maps. The application of this classification system to the suburban area around Liege reveals that, far from developing in a complete indifference of local conditions, contemporary suburban settlements are influenced by landscape structures inherited from the past. [less ▲]Detailed reference viewed: 107 (13 ULg) Overview of the Analytical Lifecycle of Supercritical Fluid Chromatography MethodsAndri, Bertyl ; Dispas, Amandine ; Marini Djang'Eing'A, Roland et alin American Journal of Analytical Chemistry (2016), 7Detailed reference viewed: 13 (3 ULg) Quand la force enfonce des portes ouvertes. Analyse du traitement de Star Wars Episode VII par la critique professionnelle et amateure.Krywicki, Boris in Culture, le Magazine Culturel de l'Université de Liège (2016)On a rarement aperçu des phénomènes cinématographiques de l’ampleur de Star Wars. La plupart des séances étaient déjà complètes plusieurs semaines avant la sortie du dernier épisode. Les spectateurs sont ... [more ▼]On a rarement aperçu des phénomènes cinématographiques de l’ampleur de Star Wars. La plupart des séances étaient déjà complètes plusieurs semaines avant la sortie du dernier épisode. Les spectateurs sont tous conquis en amont par ce messie monolithique. Quand il s'agit d'aborder un film-événement comme Star Wars, la critique de cinéma se cherche. Les timides tentatives de la rigide presse professionnelle qui hésite toujours à critiquer les productions hollywoodiennes font face à des vidéos de youtubeurs décomplexés. Cet article analyse les contrats de lecture de ces différents énonciateurs et le lecteur-modèle qu'ils envisagent pour traiter de Star Wars Episode VII. [less ▲]Detailed reference viewed: 49 (4 ULg) FLOR-ID: an interactive database of flowering-time gene networks in Arabidopsis thalianaBouché, Frédéric ; Lobet, Guillaume ; Tocquin, Pierre et alin Nucleic Acids Research (2016), 44(Database), 11671171Flowering is a hot topic in Plant Biology and important progress has been made in Arabidopsis thaliana toward unravelling the genetic networks involved. The increasing complexity and the explosion of ... [more ▼]Flowering is a hot topic in Plant Biology and important progress has been made in Arabidopsis thaliana toward unravelling the genetic networks involved. The increasing complexity and the explosion of literature however require development of new tools for information management and update. We therefore created an evolutive and interactive database of flowering time genes, named FLOR-ID (Flowering-Interactive Database), that is available freely at http://www.flor-id.org. The hand-curated database contains information on 306 genes and links to 1595 publications gathering the work of more than 4500 authors. Gene function and interactions within the flowering pathways were inferred from the analysis of related publications, included in the database and translated into interactive manually drawn snapshots. [less ▲]Detailed reference viewed: 193 (48 ULg) Shaping Pulses to Control Bistable Systems: Analysis, Computation and CounterexamplesSootla, Aivar ; Oyarzun, Diego; Angeli, David et alin Automatica (2016), 63Detailed reference viewed: 6 (1 ULg) Compte-rendu de : GÉRARD E., DE RIDDER W., MULLER F., Qui a tué Julien Lahaut ? Les ombres de la Guerre Froide en Belgique, Bruxelles, La Renaissance du Livre, 2015, 352 p.Genin, Vincent in Bulletin d'Information de l'Association Belge d'Histoire Contemporaine = Mededelingenblad van de Belgische Vereniging voor Nieuwste Geschiedenis (2016), XXXVII(2015/4), 21-24Detailed reference viewed: 21 (1 ULg) Effects of seed traits variation on seedling performance of the invasive weed, Ambrosia artemisiifolia L.Ortmans, William ; Mahy, Grégory ; Monty, Arnaud in Acta Oecologica: International Journal of Ecology (2016), 71Seedling performance can determine the survival of a juvenile plant and impact adult plant performance. Understanding the factors that may impact seedling performance is thus critical, especially for ... [more ▼]Seedling performance can determine the survival of a juvenile plant and impact adult plant performance. Understanding the factors that may impact seedling performance is thus critical, especially for annuals, opportunists or invasive plant species. Seedling performance can vary among mothers or populations in response to environmental conditions or under the influence of seed traits. However, very few studies have investigated seed traits variations and their consequences on seedling performance. Specifically, the following questions have been addressed by this work: 1) How the seed traits of the invasive Ambrosia artemisiifolia L. vary among mothers and populations, as well as along the latitude; 2) How do seed traits influence seedling performance; 3) Is the influence on seedlings temperature dependent. With seeds from nine Western Europe ruderal populations, seed traits that can influence seedling development were measured. The seeds were sown into growth chambers with warmer or colder temperature treatments. During seedling growth, performance-related traits were measured. A high variability in seed traits was highlighted. Variation was determined by the mother identity and population, but not latitude. Together, the temperature, population and the identity of the mother had an effect on seedling performance. Seed traits had a relative impact on seedling performance, but this did not appear to be temperature dependent. Seedling performance exhibited a strong plastic response to the temperature, was shaped by the identity of the mother and the population, and was influenced by a number of seed traits. [less ▲]Detailed reference viewed: 9 (2 ULg) Provenance of Ichthyosaura alpestris (Caudata: Salamandridae) introductions to France and New Zealand assessed by mitochondrial DNA analysisArntzen, Jan W.; King, Tania M.; Denoël, Mathieu et alin The Herpetological Journal (2016), 26(1), 49-56The last century has seen an unparalleled movement of species around the planet as a direct result of human activity, which has been a major contributor to the biodiversity crisis. Amphibians represent a ... [more ▼]The last century has seen an unparalleled movement of species around the planet as a direct result of human activity, which has been a major contributor to the biodiversity crisis. Amphibians represent a particularly vulnerable group, exacerbated by the devastating effects of chytrid fungi. We report the malicious translocation and establishment of the alpine newt (Ichthyosaura alpestris) to its virtual antipode in North Island of New Zealand. We use network analysis of mitochondrial DNA haplotypes to identify the original source population as I. a. apuana from Tuscany, Italy. Additionally, a population in southern France, presumed to be introduced, is identified as I. a. alpestris from western Europe. However, the presence of two differentiated haplotypes suggests a mixed origin. This type of analysis is made possible by the recent availability of a phylogenetic analysis of the species throughout its natural range. We discuss the particulars of both introductions. [less ▲]Detailed reference viewed: 379 (24 ULg) 2D dynamic studies combined with the surface curvature analysis to predict Arias Intensity amplificationTorgoev, Almazbek ; Havenith, Hans-Balder in Journal of Seismology (2016)A 2D elasto-dynamic modelling of the pure topographic seismic response is performed for six models with a total length of around 23.0 km. These models are reconstructed from the real topographic settings ... [more ▼]A 2D elasto-dynamic modelling of the pure topographic seismic response is performed for six models with a total length of around 23.0 km. These models are reconstructed from the real topographic settings of the landslide-prone slopes situated in the Mailuu-Suu River Valley, Southern Kyrgyzstan. The main studied parameter is the Arias Intensity (Ia, m/sec), which is applied in the GIS-based Newmark method to regionally map the seismically-induced landslide susceptibility. This method maps the Ia values via empirical attenuation laws and our studies investigate a potential to include topographic input into them. Numerical studies analyse several signals with varying shape and changing central frequency values. All tests demonstrate that the spectral amplification patterns directly affect the amplification of the Ia values. These results let to link the 2D distribution of the topographically amplified Ia values with the parameter called as smoothed curvature. The amplification values for the low-frequency signals are better correlated with the curvature smoothed over larger spatial extent, while those values for the high-frequency signals are more linked to the curvature with smaller smoothing extent. The best predictions are provided by the curvature smoothed over the extent calculated according to Geli’s law. The sample equations predicting the Ia amplification based on the smoothed curvature are presented for the sinusoid-shape input signals. These laws cannot be directly implemented in the regional Newmark method, as 3D amplification of the Ia values addresses more problem complexities which are not studied here. Nevertheless, our 2D results prepare the theoretical framework which can potentially be applied to the 3D domain and, therefore, represent a robust basis for these future research targets. [less ▲]Detailed reference viewed: 14 (1 ULg) Automatic artifacts and arousals detection in whole-night sleep EEG recordingsCoppieters't Wallant, Dorothée ; Muto, Vincenzo ; Gaggioni, Giulia et alin Journal of Neuroscience Methods (2016), 258In sleep electroencephalographic (EEG) signals, artifacts and arousals marking are usually part of the processing. This visual inspection by a human expert has two main drawbacks: it is very time ... [more ▼]In sleep electroencephalographic (EEG) signals, artifacts and arousals marking are usually part of the processing. This visual inspection by a human expert has two main drawbacks: it is very time consuming and subjective. To detect artifacts and arousals in a reliable, systematic and reproducible automatic way, we developed an automatic detection based on time and frequency analysis with adapted thresholds derived from data themselves. The automatic detection performance is assessed using 5 statistic parameters, on 60 whole night sleep recordings coming from 35 healthy volunteers (male and female) aged between 19 and 26. The proposed approach proves its robustness against inter- and intra-, subjects and raters’ scorings, variability. The agreement with human raters is rated overall from substantial to excellent and provides a significantly more reliable method than between human raters. Existing methods detect only specific artifacts or only arousals, and/or these methods are validated on short episodes of sleep recordings, making it difficult to compare with our whole night results. The method works on a whole night recording and is fully automatic, reproducible, and reliable. Furthermore the implementation of the method will be made available online as open source code. [less ▲]Detailed reference viewed: 50 (21 ULg) L'intentionnalité cognitive et ses modes. Reinach critique de BrentanoDewalque, Arnaud in Philosophie (2016), 128(Janvier 2016), 20-33Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai ... [more ▼]Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai mon attention sur certaines divergences significatives entre Reinach et Brentano. Après quelques réflexions introductives (§§ 1-2), j’examinerai plus exactement les questions suivantes : quels sont les motifs théoriques qui ont conduit Reinach à s’écarter de la théorie brentanienne du jugement (§§ 3-4) ? Et que retenir de ses analyses aujourd’hui (§§ 5-6) ? [less ▲]Detailed reference viewed: 89 (3 ULg) Free public transport: A socio-cognitive analysisCools, Mario ; Fabbro, Yannick; Bellemans, Tomin Transportation Research. Part A : Policy & Practice (2016), 86In this study, the modal shift potential of introducing a free alternative (free public transportation) and of changing the relative prices of transportation is examined. The influence of a cognitive ... [more ▼]In this study, the modal shift potential of introducing a free alternative (free public transportation) and of changing the relative prices of transportation is examined. The influence of a cognitive analysis on the zero-price effect is also analyzed. The data used for the analysis stem from a stated preference survey with a sample of approximately 670 respondents that was conducted in Flanders, Belgium. The data are analyzed using a mixed logit model. The modeling results yield findings that confirm the existence of a zero-price effect in transport, which is in line with the literature. This zero-price effect is increased by the forced cognitive analysis for shopping trips, although not for work/school or recreational trips. The results also demonstrate the importance of the current mode choice in hypothetical mode choices and the importance of car availability. The influence of changing relative prices on the modal shift is found to be insignificant. This might be partially because the price differences were too small to matter. Hence, an increase in public transport use can be facilitated by the introduction of free public transport, particularly when individuals evaluate the different alternatives in a more cognitive manner. These findings should be useful to policy makers evaluating free public transport and considering how best to target and promote relevant policy. [less ▲]Detailed reference viewed: 24 (1 ULg) The Perceived Value of Passive Animal Health Surveillance: The Case of Highly Pathogenic Avian Influenza in VietnamDelabouglise, Alexis; Antoine-Moussiaux, Nicolas ; Phan, T.D et alin Zoonoses and Public Health (2016), 63(2), 112-28Economic evaluations are critical for the assessment of the efficiency and sustain- ability of animal health surveillance systems and the improvement of their effi- ciency. Methods identifying and ... [more ▼]Economic evaluations are critical for the assessment of the efficiency and sustain- ability of animal health surveillance systems and the improvement of their effi- ciency. Methods identifying and quantifying costs and benefits incurred by public and private actors of passive surveillance systems (i.e. actors of veterinary author- ities and private actors who may report clinical signs) are needed. This study pre- sents the evaluation of perceived costs and benefits of highly pathogenic avian influenza (HPAI) passive surveillance in Vietnam. Surveys based on participatory epidemiology methods were conducted in three provinces in Vietnam to collect data on costs and benefits resulting from the reporting of HPAI suspicions to vet- erinary authorities. A quantitative tool based on stated preference methods and participatory techniques was developed and applied to assess the non-monetary costs and benefits. The study showed that poultry farmers are facing several options regarding the management of HPAI suspicions, besides reporting the fol- lowing: treatment, sale or destruction of animals. The option of reporting was associated with uncertain outcome and transaction costs. Besides, actors antici- pated the release of health information to cause a drop of markets prices. This cost was relevant at all levels, including farmers, veterinary authorities and private actors of the upstream sector (feed, chicks and medicine supply). One benefit associated with passive surveillance was the intervention of public services to clean farms and the environment to limit the disease spread. Private actors of the poultry sector valued information on HPAI suspicions (perceived as a non-mon- etary benefit) which was mainly obtained from other private actors and media. [less ▲]Detailed reference viewed: 70 (4 ULg) Is adult translocation a credible way to accelerate the recolonization process of Chondrostoma nasus in a rehabilitated river?Ovidio, Michaël ; Hanzen, Céline; Gennotte, Vincent et alin Cybium (2016), 40(1), 43-49The decline of the patrimonial rheophilic nase, Chondrostoma nasus (Linnaeus, 1758) populations was mainly caused by construction of dams and hydroelectric power-plants, together with the straightening ... [more ▼]The decline of the patrimonial rheophilic nase, Chondrostoma nasus (Linnaeus, 1758) populations was mainly caused by construction of dams and hydroelectric power-plants, together with the straightening and artificialization of the river banks and water pollution. In this study, we tested the hypothesis whether the translocation of few adult nase individuals from a river stretch to another upstream may be a credible way to accelerate the recolonization process of the species in the Amblève River (Southern Belgium). In February and March 2011, just before their spawning period, eight adult nases (462-509 mm; 1546-2002 g; presumed males and females) were captured in the lower part of the River Amblève. Fin clip samples were stored in alcohol for further genetic analysis. They were equipped with a 14 g radio transmitter and translocated upstream in a 18 km river stretch, where the species had disappeared since decades due to river anthropization. They were manually located two to five times/week using mobile receivers until maximum June 2012 (n = 977 locations). River temperature and flow were hourly recorded during the entire tracking period. The tagged nase individuals displayed various mobility patterns, exploited different areas of the river stretch, occupied longitudinal home ranges from 3.4 to 36.1 km (one individual finally left the new river stretch) and travelled total distances from 12.2 to 186.6 km. The tagged individuals were most of the times apart from one to another, but most individuals grouped together in potential spawning areas in late March-early April 2011, suggesting an attempt to reproduce. In September 2011, electric fishing in two potential detected spawning sites allowed to capture 16 juvenile (0+) nases, demonstrating the existence of spawning activity in the newly occupied river stretch. Individual genetic characterization was performed in 2014 in order to reveal a possible direct lineage between juveniles and adults. Allelic distribution of 22 microsatellite markers unambiguously identified the 16 juveniles as full-sib progeny descending from two of the translocated adults. This demonstrated that the adult nases succeeded to find spawning areas and that progeny found raised-up from the translocated individuals. [less ▲]Detailed reference viewed: 88 (12 ULg) compte rendu de : Johannes CHRISTES-Giovanni GARBUGINO (Ed.), Lucilius. Satiren. Lateinisch und deutsch. Eingeleitet, űbersetzt und erlautert von J.C. und G.G.Rochette, Bruno in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2016)Detailed reference viewed: 35 (0 ULg) Comparison of Moving Boundary and Finite-Volume Heat Exchanger Models in the Modelica LanguageDesideri, Adriano ; Dechesne, Bertrand ; Wronski, Jorrit et alin energies (2016)When modeling low capacity energy systems, such as a small size (5–150kWel) organic Rankine cycle unit, the governing dynamics are mainly concentrated in the heat exchangers. As a consequence, the ... [more ▼]When modeling low capacity energy systems, such as a small size (5–150kWel) organic Rankine cycle unit, the governing dynamics are mainly concentrated in the heat exchangers. As a consequence, the accuracy and simulation speed of the higher level system model mainly depend on the heat exchanger model formulation. In particular, the modeling of thermo-flow systems characterized by evaporation or condensation requires heat exchanger models capable of handling phase transitions. To this aim, the finite volume (FV) and the moving boundary (MB) approaches are the most widely used. The two models are developed and included in the open-source ThermoCycle Modelica library. In this contribution, a comparison between the two approaches is presented. An integrity and accuracy test is designed to evaluate the performance of the FV and MB models during transient conditions. In order to analyze how the two modeling approaches perform when integrated at a system level, two organic Rankine cycle (ORC) system models are built using the FV and the MB evaporator model, and their responses are compared against experimental data collected on an 11kWel ORC power unit. Additionally, the effect of the void fraction value in the MB evaporator model and of the number of control volumes (CVs) in the FV one is investigated. The results allow drawing general guidelines for the development of heat exchanger dynamic models involving two-phase flows. [less ▲]Detailed reference viewed: 14 (3 ULg) Is the Nociception Coma Scale-Revised a Useful Clinical Tool for Managing Pain in Patients with Disorders of Consciousness?Chatelle, Camille ; De Val, Marie Daniele; Catano, Antonio et alin The Clinical journal of pain (2016)OBJECTIVES: Our objective was to assess the clinical interest of the Nociception Coma Scale Revised (NCS-R) in pain management of patients with disorders of consciousness. METHODS: Thirty-nine patients ... [more ▼]OBJECTIVES: Our objective was to assess the clinical interest of the Nociception Coma Scale Revised (NCS-R) in pain management of patients with disorders of consciousness. METHODS: Thirty-nine patients with potential painful conditions (e.g., due to fractures, decubitus ulcers or spasticity) were assessed during nursing cares before and after the administration of an analgesic treatment tailored to each patient's clinical status. In addition to the NCS-R, the Glasgow Coma Scale (GCS) was used before and during treatment in order to observe fluctuations in consciousness. Twenty-three of them had no analgesic treatment prior to the assessment whereas the analgesic treatment has been adapted in the other 16 patients. We performed non-parametric Wilcoxon tests to investigate the difference in the NCS-R and GCS total scores but also in the NCS-R subscores before versus during treatment. The effect of the level of consciousness and the etiology were assessed using a U Mann Whitney. RESULTS: NCS-R total scores were statistically lower during treatment when compared to the scores obtained before treatment. We also found that the motor, verbal and facial expression subscores were lower during treatment than before treatment. On the other hand, we found no difference between the GCS total scores obtained before versus during treatment. DISCUSSION: Our results suggest that the NCS-R is an interesting clinical tool for pain management. Besides, this tool seems useful when a balance is needed between reduced pain and preserved level of consciousness in patients with disorders of consciousness. [less ▲]Detailed reference viewed: 23 (4 ULg) wicking through a confined micropillar arrayDarbois-Texier, Baptiste ; Laurent, Philippe ; Stoukatch, Serguei et alin Microfluidics and Nanofluidics (2016), 20Detailed reference viewed: 35 (7 ULg) A multi-scale magnetotail reconnection event at Saturn and associated flows: Cassini/UVIS observationsRadioti, Aikaterini ; Grodent, Denis ; Jia, X. et alin Icarus (2016)Detailed reference viewed: 52 (23 ULg) Quadratization of symmetric pseudo-Boolean functionsAnthony, Martin; Boros, Endre; Crama, Yves et alin Discrete Applied Mathematics (2016), 203A pseudo-Boolean function is a real-valued function $f(x)=f(x_1,x_2,\ldots,x_n)$ of $n$ binary variables; that is, a mapping from $\{0,1\}^n$ to ${\bbr}$. For a pseudo-Boolean function $f(x)$ on $\{0,1 ... [more ▼]A pseudo-Boolean function is a real-valued function$f(x)=f(x_1,x_2,\ldots,x_n)$of$n$binary variables; that is, a mapping from$\{0,1\}^n$to${\bbr}$. For a pseudo-Boolean function$f(x)$on$\{0,1\}^n$, we say that$g(x,y)$is a quadratization of$f$if$g(x,y)$is a Quadratic polynomial depending on$x$and on$m$auxiliary binary variables$y_1,y_2,\ldots,y_m$such that$f(x)= \min \{ g(x,y) : y \in \{0,1\}^m \} $for all$x \in \{0,1\}^n$. By means of quadratizations, minimization of$f$is reduced to minimization (over its extended set of variables) of the quadratic function$g(x,y)$. This is of some practical interest because minimization of quadratic functions has been thoroughly studied for the last few decades, and much progress has been made in solving such problems exactly or heuristically. A related paper initiated a systematic study of the minimum number of auxiliary$y$-variables required in a quadratization of an arbitrary function$f$(a natural question, since the complexity of minimizing the quadratic function$g(x,y)$depends, among other factors, on the number of binary variables). In this paper, we determine more precisely the number of auxiliary variables required by quadratizations of \emph{symmetric} pseudo-Boolean functions$f(x)$, those functions whose value depends only on the Hamming weight of the input$x\$ (the number of variables equal to 1). [less ▲]Detailed reference viewed: 83 (12 ULg) EACVI appropriateness criteria for the use of cardiovascular imaging in heart failure derived from European National Imaging Societies voting.Garbi, Madalina; Edvardsen, Thor; Bax, Jeroen et alin European heart journal cardiovascular Imaging (2016)This paper presents the first European appropriateness criteria for the use of cardiovascular imaging in heart failure, derived from voting of the European National Imaging Societies representatives. The ... [more ▼]This paper presents the first European appropriateness criteria for the use of cardiovascular imaging in heart failure, derived from voting of the European National Imaging Societies representatives. The paper describes the development process and discusses the results. [less ▲]Detailed reference viewed: 11 (1 ULg) Les catégories au seuil de la phénoménologieGauvry, Charlotte ; Fagniez, Guillaumein Etudes Philosophiques (Les) (2016)Le tournant du XXe siècle est marqué par un retour de la problématique catégoriale sur le devant de la scène philosophique, que ce soit chez Franz Brentano et ses élèves, chez Wilhelm Dilthey, chez les ... [more ▼]Le tournant du XXe siècle est marqué par un retour de la problématique catégoriale sur le devant de la scène philosophique, que ce soit chez Franz Brentano et ses élèves, chez Wilhelm Dilthey, chez les Néokantiens de l’école de Bade, ou chez les premiers pionniers de la phénoménologie. Tant et si bien qu’une certaine philosophie (celle d’Emil Lask par excellence) a pu se présenter comme une doctrine des catégories à part entière. L’enjeu de ce numéro est d’interroger la place historique et le rôle conceptuel qu’ont joué ces questions formelles dans l’émergence de la phénoménologie. Kant avait certes renoué avec la question aristotélicienne des catégories pour postuler l’existence de « purs concepts de l’entendement » ou « catégories », seuls susceptibles de « fournir de l’unité aux diverses représentations dans un jugement et [de] donner aussi à la simple synthèse de diverses représentations dans une intuition une unité » (KRV, §10). L’intérêt proto-phénoménologique pour les catégories se présente-t-il cependant comme un retour, par-delà l’idéalisme allemand, à cette problématique transcendantale kantienne ou bien plutôt comme un retour, par-delà Kant lui-même, à la question aristotélicienne ? Si les philosophes du début XXe se sont ressaisis de la question des catégories, il semble qu’ils aient à tout le moins reformulé, voire abandonné la méthode de la « déduction ». C’est ce travail de reformulation de la déduction transcendantale que le numéro entend également clarifier. Peut-on encore dire que ces catégories sont « déduites » des formes logiques du jugement, des objets logiques ou du mouvement même de la vie ? S’il y a lieu de mettre au jour un processus « génétique » de la catégorie, quelles sont les implications d’un tel déplacement relativement à la validité du catégorial ? Plus généralement, c’est le statut même de ces « catégories » qui sera analysé. Leur domaine d’application redéfini, peut-on les déterminer comme des concepts purs transcendantaux susceptibles d’unifier l’expérience sensible ? Les catégories ne doivent-elles pas plutôt être repensées comme des formes logiques, sémantiques ou même ontologiques ? Ainsi, c’est l’enjeu stratégique de la résurgence de cette problématique catégoriale, et ses répercussions directes sur l’émergence de la phénoménologie naissante (husserlienne et heideggérienne) que ce numéro interrogera. [less ▲]Detailed reference viewed: 42 (3 ULg) La cognitivo-linguistique : pour une tentative de rapprochement de la clinique et de l'actuarielCourtain, Audrey ; Glowacz, Fabienne in Revue Internationale de Criminologie et de Police Technique et Scientifique [= RICPTS] (2016), 1Anchored in the actuarial field, risk assessment is a tool clinicians are more and more likely to use (because they can or have to) among delinquents. But, due to epistemological differences, an important ... [more ▼]Anchored in the actuarial field, risk assessment is a tool clinicians are more and more likely to use (because they can or have to) among delinquents. But, due to epistemological differences, an important debate has been occurring between the clinical evaluation and the actuarial one since the fifties. This paper suggests a media between those perspectives through cognitive linguistics: it allows a complementary articulation, while insisting on what is at stake for both clinical and actuarial developments. Linking language and cognitions, the paper introduces a reflexion that may be useful to actuarial assessment and clinical support, and may facilitate rapprochement between the latter. In this case, our linguistic approach focusses on different matters targeted by actuarial tools and whose clinical understanding may be deepened by studying the link between language and cognition; this clinical understanding bringing singularity to risk assessment. [less ▲]Detailed reference viewed: 28 (5 ULg) Compte rendu de Christophe CHANDEZON, Julien DU BOUCHET (éds.), Artémidore de Daldis et l’interprétation des rêves. Quatorze étudesBerg, Tatiana in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2016), 85Detailed reference viewed: 18 (1 ULg) Monitoring the freshness of fish: development of a qPCR method applied to MAP chilled whitingDehaut, Alexandre; Krzewinski, Frédéric; Grard, Thierry et alin Journal of the Science of Food and Agriculture (2016)Detailed reference viewed: 12 (1 ULg) The role of active site flexible loops in catalysis and of zinc in conformational stability of Bacillus cereus 569/H/9 beta-lactamase.Montagner, Caroline ; Nigen, Michaël; Jacquin, Olivier et alin Journal of Biological Chemistry (2016)Metallo-beta-lactamases catalyse the hydrolysis of most beta-lactam antibiotics and hence represent a major clinical concern. The development of inhibitors for these enzymes is complicated by the ... [more ▼]Metallo-beta-lactamases catalyse the hydrolysis of most beta-lactam antibiotics and hence represent a major clinical concern. The development of inhibitors for these enzymes is complicated by the diversity and flexibility of their substrate binding sites, motivating research into their structure and function. In this study, we examined the conformational properties of the Bacillus cereus beta-lactamase II in the presence of chemical denaturants using a variety of biochemical and biophysical techniques. The apoenzyme was found to unfold cooperatively, with a Gibbs free energy of stabilization (DeltaG degrees ) of 32 +/- 2 kJ.mol11. For holoBcII, a first non-cooperative transition leads to multiple interconverting native-like states, in which both zinc atoms remain bound in an apparently unaltered active site and the protein displays a well-organized compact hydrophobic core with structural changes confined to the enzyme surface, but with no catalytic activity. 2D NMR data revealed that the loss of activity occurs concomitantly with perturbations in two loops that border the enzyme active site. A second cooperative transition, corresponding to global unfolding, is observed at higher denaturant concentrations, with DeltaG degrees value of 65 +/- 1.4 kJ.mol11. These combined data highlight the importance of the two zinc ions in maintaining structure as well as a relatively well-defined conformation for both active site loops in order to maintain enzymatic activity. [less ▲] Correlation between resting state fMRI total neuronal activity and PET metabolism in healthy controls and patients with disorders of consciousnessSoddu, Andrea ; Gomez, Francisco; Heine, Lizette et alin Brain and Behavior (2016)Introduction: The mildly invasive 18F-ﬂuorodeoxyglucose positron emission tomography (FDG-PET) is a well-established imaging technique to measure ‘resting state’ cerebral metabolism. This technique made ... [more ▼]Introduction: The mildly invasive 18F-ﬂuorodeoxyglucose positron emission tomography (FDG-PET) is a well-established imaging technique to measure ‘resting state’ cerebral metabolism. This technique made it possible to assess changes in metabolic activity in clinical applications, such as the study of severe brain injury and disorders of consciousness. Objective: We assessed the possi- bility of creating functional MRI activity maps, which could estimate the rela- tive levels of activity in FDG-PET cerebral metabolic maps. If no metabolic absolute measures can be extracted, our approach may still be of clinical use in centers without access to FDG-PET. It also overcomes the problem of recogniz- ing individual networks of independent component selection in functional mag- netic resonance imaging (fMRI) resting state analysis. Methods: We extracted resting state fMRI functional connectivity maps using independent component analysis and combined only components of neuronal origin. To assess neu- ronality of components a classiﬁcation based on support vector machine (SVM) was used. We compared the generated maps with the FDG-PET maps in 16 healthy controls, 11 vegetative state/unresponsive wakefulness syndrome patients and four locked-in patients. Results: The results show a signiﬁcant similarity with q = 0.75  0.05 for healthy controls and q = 0.58  0.09 for vegetative state/unresponsive wakefulness syndrome patients between the FDG- PET and the fMRI based maps. FDG-PET, fMRI neuronal maps, and the conjunction analysis show decreases in frontoparietal and medial regions in vegetative patients with respect to controls. Subsequent analysis in locked-in syndrome patients produced also consistent maps with healthy controls. Conclusions: The constructed resting state fMRI functional connectivity map points toward the possibility for fMRI resting state to estimate relative levels of activity in a metabolic map. [less ▲]Detailed reference viewed: 56 (11 ULg) Middle Devonian Jawed polychate fauna from the type Eifel area, western Germany, and its biogeographical and evolutionary affinitiesTonarova, Petra; Hints, Olle; Könighsof, Peter et alin Palaeontology (2016)Detailed reference viewed: 30 (3 ULg) Prognostic relevance of epilepsy at presentation in glioblastoma patients.Berendsen, Sharon; Varkila, Meri; Kroonen, Jerome et alin Neuro-oncology (2016)BACKGROUND: Epileptogenic glioblastomas are thought to convey a favorable prognosis, either due to early diagnosis or potential antitumor effects of antiepileptic drugs. We investigated the relationship ... [more ▼]BACKGROUND: Epileptogenic glioblastomas are thought to convey a favorable prognosis, either due to early diagnosis or potential antitumor effects of antiepileptic drugs. We investigated the relationship between survival and epilepsy at presentation, early diagnosis, and antiepileptic drug therapy in glioblastoma patients. METHODS: Multivariable Cox regression was applied to survival data of 647 consecutive patients diagnosed with de novo glioblastoma between 2005 and 2013 in order to investigate the association between epilepsy and survival in glioblastoma patients. In addition, we quantified the association between survival and valproic acid (VPA) treatment. RESULTS: Epilepsy correlated positively with survival (HR: 0.75 (95% CI: 0.61-0.92), P < .01). This effect is independent of age, sex, performance status, type of surgery, adjuvant therapy, tumor location, and tumor volume, suggesting that this positive correlation cannot be attributed solely to early diagnosis. For patients who presented with epilepsy, the use of the antiepileptic drug VPA did not associate with survival when compared with patients who did not receive VPA treatment. CONCLUSION: Epilepsy is an independent prognostic factor for longer survival in glioblastoma patients. This prognostic effect is not solely explained by early diagnosis, and survival is not associated with VPA treatment. [less ▲]Detailed reference viewed: 18 (4 ULg) The Robust Economic Statistical Design of the Hotelling’s T^2 ChartFaraz, Alireza ; Chalaki, Kamyar; Saniga, Erwin et alin Communications in Statistics : Theory & Methods (2016)Economic statistical designs aim at minimizing the cost of process monitoring when a specific scenario or a set of estimated process and cost parameters is given. However, in practical situations the ... [more ▼]Economic statistical designs aim at minimizing the cost of process monitoring when a specific scenario or a set of estimated process and cost parameters is given. However, in practical situations the process may be affected by more than one scenario which may lead to severe cost penalties for upsetting the true scenario. This paper presents the robust economic statistical design (RESD) of the T^2 chart to reduce the monetary losses when there are multiple distinct scenarios. The genetic algorithm optimization method is employed here to minimize the total expected monitoring cost across all distinct scenarios. Through two numerical examples the proposed method is illustrated. Simulation studies indicate that the robust economic statistical designs should be encouraged in practice. [less ▲]Detailed reference viewed: 72 (3 ULg) Current Changes in Pubertal Timing: Revised Vision in Relation with Environmental Factors Including Endocrine Disruptors.Parent, Anne-Simone ; Franssen, Delphine ; Fudvoye, Julie et alin Endocrine development (2016), 29The aim of this chapter is to revise some common views on changes in pubertal timing. This revision is based on recent epidemiological findings on the clinical indicators of pubertal timing and data on ... [more ▼]The aim of this chapter is to revise some common views on changes in pubertal timing. This revision is based on recent epidemiological findings on the clinical indicators of pubertal timing and data on environmental factor effects and underlying mechanisms. A current advancement in timing of female puberty is usually emphasized. It appears, however, that timing is also changing in males. Moreover, the changes are towards earliness for initial pubertal stages and towards lateness for final stages in both sexes. Such observations indicate the complexity of environmental influences on pubertal timing. The mechanisms of changes in pubertal timing may involve both the central neuroendocrine control and peripheral effects at tissues targeted by gonadal steroids. While sufficient energy availability is a clue to the mechanism of pubertal development, changes in the control of both energy balance and reproduction may vary under the influence of common determinants such as endocrine-disrupting chemicals (EDCs). These effects can take place right before puberty as well as much earlier, during fetal and neonatal life. Finally, environmental factors can interact with genetic factors in determining changes in pubertal timing. Therefore, the variance in pubertal timing is no longer to be considered under absolutely separate control by environmental and genetic determinants. Some recommendations are provided for evaluation of EDC impact in the management of pubertal disorders and for possible reduction of EDC exposure along the precautionary principle. [less ▲]Detailed reference viewed: 31 (10 ULg) Quasi-periodic injections of relativistic electrons in Saturn's outer magnetosphereRoussos, E.; Krupp, N.; Mitchell, D. G. et alin Icarus (2016), 263Detailed reference viewed: 18 (3 ULg) Ready for Change!Nchimi Longang, Alain in Journal of the Belgian Society of Radiology (2016)Detailed reference viewed: 12 (2 ULg) Flexible estimation in cure survival models using Bayesian P-splinesBremhorst, Vincent; Lambert, Philippe in Computational Statistics & Data Analysis (2016), 93In the analysis of survival data, it is usually assumed that any unit will experience the event of interest if it is observed for a sufficiently long time. However, it can be explicitly assumed that an ... [more ▼]In the analysis of survival data, it is usually assumed that any unit will experience the event of interest if it is observed for a sufficiently long time. However, it can be explicitly assumed that an unknown proportion of the population under study will never experience the monitored event. The promotion time model, which has a biological motivation, is one of the survival models taking this feature into account. The promotion time model assumes that the failure time of each subject is generated by the minimum of N independent latent event times with a common distribution independent of N. An extension which allows the covariates to influence simultane- ously the probability of being cured and the latent distribution is presented. The latent distribution is estimated using a flexible Cox proportional hazard model where the logarithm of the baseline hazard function is specified using Bayesian P-splines. Introducing covariates in the latent distribution implies that the population hazard function might not have a proportional hazard structure. However, the use of P- splines provides a smooth estimation of the population hazard ratio over time. The identification issues of the model are discussed and a restricted use of the model when the follow up of the study is not sufficiently long is proposed. The accuracy of our methodology is evaluated through a simulation study and the model is illustrated on data from a Melanoma clinical trial. [less ▲]Detailed reference viewed: 28 (4 ULg) Ontogenic variation and effect of collection procedure on leaf biomechanical properties of Mediterranean seagrass Posidonia oceanica (L.) Delilede los santos, Carmen; Vicencio, Barbara; Lepoint, Gilles et alin Marine Ecology (2016)Leaf mechanical traits are important to understand how aquatic plants fracture and deform when subjected to abiotic (currents or waves) or biotic (herbivory attack) mechanical forces. The likely ... [more ▼]Leaf mechanical traits are important to understand how aquatic plants fracture and deform when subjected to abiotic (currents or waves) or biotic (herbivory attack) mechanical forces. The likely occurrence of variation during leaf onto- geny in these traits may thus have implications for hydrodynamic performance and vulnerability to herbivory damage, and may be associated with changes in morphologic and chemical traits. Seagrasses, marine flowering plants, consist of shoot bundles holding several leaves with different developmental stages, in which outer older leaves protect inner younger leaves. In this study we examined the long-lived seagrass Posidonia oceanica to determine ontogenic variation in mechanical traits across leaf position within a shoot, representing different devel- opmental stages. Moreover, we investigated whether or not the collection proce- dure (classical uprooted shoot versus non-destructive shoot method: cutting the shoot without a portion of rhizome) and time span after collection influence mechanical measurements. Neither collection procedure nor time elapsed within 48 h of collection affected measurements of leaf biomechanical traits when sea- grass shoots were kept moist in dark cool conditions. Ontogenic variation in mechanical traits in P. oceanica leaves over intermediate and adult developmen- tal stages was observed: leaves weakened and lost stiffness with aging, while mid- aged leaves (the longest and thickest ones) were able to withstand higher break- ing forces. In addition, younger leaves had higher nitrogen content and lower fiber content than older leaves. The observed patterns may explain fine-scale within-shoot ecological processes of leaves at different developmental stages, such as leaf shedding and herbivory consumption in P. oceanica. [less ▲]Detailed reference viewed: 11 (2 ULg) A general parametric Stein characterizationSwan, Yvik ; Ley, Christophein Statistics & Probability Letters (2016), 111Detailed reference viewed: 26 (2 ULg) Examen de jurisprudence (2010-2013) - Les sociétés commerciales (première partie)Caprasse, Olivier ; Dieux, Xavier; Lambrecht, Philippein Revue Critique de Jurisprudence Belge [= RCJB] (2016)Detailed reference viewed: 16 (0 ULg) Combinaison fixe atorvastatine-ezetimibe (Atozet(R)).Scheen, André in Revue medicale de Liege (2016), 71(1), 47-52Cardiovascular prevention in subjects at high or very high risk requires a drastic reduction in LDL cholesterol according to the concept "the lower, the better". The combination of an inhibitor of ... [more ▼]Cardiovascular prevention in subjects at high or very high risk requires a drastic reduction in LDL cholesterol according to the concept "the lower, the better". The combination of an inhibitor of cholesterol synthesis and a selective inhibitor of intestinal absorption results in a complementary and synergistic LDL-lowering activity. Besides a first fixed combination ezetimibe-simvastatin (Inegy(R)), a new fixed combination is presented, Atozet(R) that combines atorvastatin and ezetimibe. Because atorvastatin is more potent than simvastatin, this novel fixed combination should facilitate reaching therapeutic goals in terms of LDL cholesterol amongst patients with severe hypercholesterolaemia and/or at high or very high cardiovascular risk. [less ▲]Detailed reference viewed: 21 (2 ULg) Étude des potentialités des systèmes d’application contrôlée des gouttes (CDA) pour les traitements phytosanitaires en céréaliculture (synthèse bibliographique)Ouled Taleb Salah, Sofiene ; De Cock, Nicolas ; Massinon, Mathieu et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment (2016)Introduction. L’application contrôlée des gouttes (CDA) présente le double avantage de réduire à la fois l’étendue de la distribution des tailles des gouttes et le volume appliqué par rapport aux buses ... [more ▼]Introduction. L’application contrôlée des gouttes (CDA) présente le double avantage de réduire à la fois l’étendue de la distribution des tailles des gouttes et le volume appliqué par rapport aux buses hydrauliques conventionnelles. Littérature. Cette revue investigue la potentialité de la CDA par rapport aux buses hydrauliques dans le cadre du désherbage précoce des adventices (2-3 feuilles). En termes de rétention, les études reliant les caractéristiques des gouttes (taille, vitesse et direction) et l’architecture, la densité et la mouillabilité du feuillage, en fonction de la formulation de bouillies, ont été abordées. Ces études montrent que des gouttes de 300 μm avec un adjuvant approprié et des jets émis 60° vers l’avant par rapport à la verticale contribuent à l’augmentation de la rétention sur les cibles problématiques à port dressé. L’effet des réductions des volumes d’application pour ces deux techniques est étudié sur base de la moyenne, du coefficient de variation et du taux de couverture des dépôts. Néanmoins, les résultats de ces études ne peuvent être généralisés du fait des différences de réglages opératoires entre les deux techniques d’application. Quant à la dérive, les atomiseurs CDA orientés horizontalement présentent un potentiel de dérive plus important que les buses hydrauliques pour lesquelles le spray est orienté vers le bas. La dérive augmente avec la vitesse du vent et diminue lorsque le diamètre médian volumétrique (DV50) augmente. Conclusions. De nouveaux réglages des atomiseurs de la CDA en termes de DV50 et de direction du jet peuvent répondre aux défis de l’agriculture de précision. Les pistes d’innovations proposées sont d’une part une amélioration de la résistance à l’usure des dents situées en bordure des disques et, d’autre part, une distribution granulométrique plus étroite. [less ▲]Detailed reference viewed: 25 (4 ULg) Response to novely and cocaine stimulant effects: lack of stability across environments in female Swiss miceNyssen, Laura ; Brabant, Christian ; Didone, Vincent et alin Psychopharmacology (2016), 233Rationale: In humans, novelty/sensation seeking is seen as a personality trait with a positive relationship with addiction vulnerability. In animal studies, one of the standard proce-dures to model ... [more ▼]Rationale: In humans, novelty/sensation seeking is seen as a personality trait with a positive relationship with addiction vulnerability. In animal studies, one of the standard proce-dures to model novelty seeking is the "response to novelty," i.e., the levels of locomotor activity in a new environment. In rodents, a positive correlation was demonstrated between the response to novelty and several effects of drugs, especially the locomotor stimulant effects of cocaine. Objectives: The present study was designed to test in mice whether the response to novelty is stable across environments and whether its relationship with the stimulant effects of cocaine is altered by environmental changes. Experiment 1 assessed the responses to novelty of the same mice in two different novel environments. Experiment 2 tested the correlation between response to novelty and acute stimulant effects of cocaine recorded in two distinct environments. Results: The results show a weak correlation only during the first 5 min of the session between the responses to novelty measured in two distinct environments. Experiment 2 demonstrates that novelty responses and stimulant effects of cocaine are positively correlated only when both behavioral responses are measured in the same environment. In contrast, the relationship between response to novelty and acute stimulant effects of cocaine is completely lost when the behavioral responses are recorded in two different environments. Conclusions: The present results question the usual interpretation of the correlation between the response to novelty and the stimulant effects of cocaine as reflecting a relationship between two underlying individual stable characteristics. [less ▲]Detailed reference viewed: 14 (4 ULg) Bovine noroviruses: A missing component of calf diarrhoea diagnosisDi Felice, Elisabetta; Mauroy, Axel ; Dal Pozzo, Fabiana et alin Veterinary Journal (2016), 207Detailed reference viewed: 93 (17 ULg) Quantitative assessment of mouse mammary gland morphology using automated digital image processing and TEB detection.Blacher, Silvia ; Gérard, Céline ; Gallez, Anne et alin Endocrinology (2016)The assessment of rodent mammary gland morphology is largely used to study the molecular mechanisms driving breast development and to analyze the impact of various endocrine disruptors with putative ... [more ▼]The assessment of rodent mammary gland morphology is largely used to study the molecular mechanisms driving breast development and to analyze the impact of various endocrine disruptors with putative pathological implications. In this work, we propose a methodology relying on fully automated digital image analysis methods including image processing and quantification of the whole ductal tree and of the terminal end buds (TEB) as well. It allows to accurately and objectively measure both growth parameters and fine morphological glandular structures. Mammary gland elongation was characterized by two parameters: the length and the epithelial area of the ductal tree. Ductal tree fine structures were characterized by: 1) branch end-point density, 2) branching density and 3) branch length distribution. The proposed methodology was compared to quantification methods classically used in the literature. This procedure can be transposed to several software and thus largely used by scientists studying rodent mammary gland morphology. [less ▲]Detailed reference viewed: 31 (6 ULg) A comprehensive density functional theory study of the key role of fluorination and dual hydrogen bonding in the activation of the epoxide/CO2 coupling by fluorinated alcoholsAlves, Margot ; Méreau, Raphaël; Grignard, Bruno et alin RSC Advances (2016), 6(43), 36327-36335The activation mechanism of the CO2/propylene oxide coupling catalysed by a bicomponent organocatalyst combining the use of TBABr with (multi)phenolic or fluorinated hydrogen bond donors (HBDs) was ... [more ▼]The activation mechanism of the CO2/propylene oxide coupling catalysed by a bicomponent organocatalyst combining the use of TBABr with (multi)phenolic or fluorinated hydrogen bond donors (HBDs) was investigated using the Density Functional Theory (DFT). Thus, it was shown that increasing the number of electron withdrawing trifluoromethyl substituents in HBDs strengthens their proton donor capability and allows a better stabilization by hydrogen bonding of the intermediates and transition states. In addition, the high efficiency of fluorinated monoalcohol activators is related to a dual hydrogen bonding mechanism by two fluorinated molecules that cooperatively contribute to the CO2/propylene oxide coupling. [less ▲]Detailed reference viewed: 20 (6 ULg) Impact of climatic factors on the release of E-β-caryophyllene from alginate beadsDaems, Frédéric ; Bera, François ; Lorge, Stéphanie et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2016), 20(2), Description of the subject. Alginate beads that release semiochemical compounds are interesting biological control devices used to attract the natural enemies of aphids in infested crops. Little ... [more ▼]Description of the subject. Alginate beads that release semiochemical compounds are interesting biological control devices used to attract the natural enemies of aphids in infested crops. Little information, however, is available about the impact of climatic factors on the release of semiochemicals from this diffusive system. Objectives. The objective of this scoping study was to investigate the impact of temperature, relative humidity and wind speed, on the release of E-β-caryophyllene from alginate beads. Method. The impact of the three climatic factors on the release of E-β-caryophyllene from alginate beads was evaluated using a Box-Behnken experimental design and a laboratory scale volatile collection system. The influence of relative humidity on bead water content and size, with and without this semiochemical, was also investigated using a gravimetric method and an easy-to-use photographic device, respectively. Results. The results showed that an increase in temperature caused a significant increase in the E-β¬-caryophyllene release rate. Neither relative humidity nor airflow, however, had a significant effect on the release of this semiochemical when relative humidity and wind speed ranged from 33% to 75% and from 6.61 x10-4 m.s-1 to 2.05 x10-2 m.s-1, respectively. The isotherm curves obtained were characteristic of food products and biopolymer materials. The isotherm shapes were not modified by the incorporation of the semiochemical into alginate beads, and showed an important increase in water content when relative humidity values exceeded 85%. Fortunately, this water content increase did not affect bead size, which facilitates the calculation of E-β-caryophyllene release. Conclusion. The present study shows for the first time the impact of the three main climatic factors on the release of E-β-caryophyllene from alginate beads. It allows learning more about how these biological control devices operate in order to optimize future field trials. [less ▲]Detailed reference viewed: 36 (3 ULg) New data about anatomy, branching, and inferred growth patterns in the Early Devonian plant Armoricaphyton chateaupannense, Montjean-sur-Loire, FranceGerrienne, Philippe ; Gensel, PGin Review of Palaeobotany and Palynology (2016), 224(Part 1), 38-53This study provides detailed information, based on serial peels, on the anatomy of the primary and secondary xylem, lateral branch formation, and proposed growth pattern of Armoricaphyton Strullu-Derrien ... [more ▼]This study provides detailed information, based on serial peels, on the anatomy of the primary and secondary xylem, lateral branch formation, and proposed growth pattern of Armoricaphyton Strullu-Derrien et al., an Early Devonian (Pragian) basal euphyllophyte. The centrarch primary xylem strand is circular to oval in cross section and includes P-type tracheids. The pattern of lateral branch departure is described in detail based on serial peels. The secondary xylem, illustrated in transverse, radial and tangential longitudinal sections, includes P-type tracheids with similar pitting in radial and tangential walls. The presence of one-walled spaces interpreted as rays is confirmed. This study also documents the earliest occurrence of secondary xylem at bases of next higher order of branches. A model of growth for this unusual Early Devonian plant is presented, with documented epidogenetic, menetogenetic and possible apoxogenetic phases. The difference in proportion of primary tosecondary xylem is postulated to be a result of this mode of growth. The possible implications of xylem size and organization in the lateral organ in Armoricaphyton relative to the early evolution of the megaphyllous leaf are briefly discussed. [less ▲]Detailed reference viewed: 16 (4 ULg) Decitabine improves progression-free survival in older high-risk MDS patients with multiple autosomal monosomies: results of a subgroup analysis of the randomized phase III study 06011 of the EORTC Leukemia Cooperative Group and German MDS Study GroupLübbert, Michael; Suciu, Stefan; Hagemeijer, Anne et alin Annals of Hematology (2016), 95In a study of elderly AML patients treated with the hypomethylating agent decitabine (DAC), we noted a surprisingly favorable outcome in the (usually very unfavorable) subgroup with two or more autosomal ... [more ▼]In a study of elderly AML patients treated with the hypomethylating agent decitabine (DAC), we noted a surprisingly favorable outcome in the (usually very unfavorable) subgroup with two or more autosomal monosomies (MK2+) within a complex karyotype (Lübbert et al., Haematologica 97:393-401, 2012). We now analyzed 206 myelodysplastic syndrome (MDS) patients (88 % of 233 patients randomized in the EORTC/GMDSSG phase III trial 06011, 61 of them with RAEBt, i.e. AML by WHO) with cytogenetics informative for MK status.. Endpoints are the following: complete/partial (CR/PR) and overall response rate (ORR) and progression-free (PFS) and overall survival (OS). Cytogenetic subgroups are the following: 63 cytogenetically normal (CN) patients, 143 with cytogenetic abnormalities, 73 of them MKnegative (MK−), and 70 MK-positive (MK+). These MK+ patients could be divided into 17 with a single autosomal monosomy (MK1) and 53 with at least two monosomies (MK2+). ORR with DAC in CN patients: 36.1 %, in MK−patients: 16.7 %, in MK+ patients: 43.6 % (MK1: 44.4 %, MK2+ 43.3 %). PFS was prolonged by DAC compared to best supportive care (BSC) in the CN (hazard ratio (HR) 0.55, 99 % confidence interval (CI), 0.26; 1.15, p=0.03) and MK2+ (HR 0.50; 99%CI, 0.23; 1.06, p=0.016) but not in the MK−, MK+, and MK1 subgroups. OS was not improved by DAC in any subgroup. In conclusion, we demonstrate for the first time in a randomized phase III trial that high-risk MDS patients with complex karyotypes harboring two or more autosomal monosomies attain encouraging responses and have improved PFS with DAC treatment compared to BSC. [less ▲]Detailed reference viewed: 6 (1 ULg) Consumer acceptance of insect-based alternative meat products in Western countriesCaparros Megido, Rudy ; Gierts, Chloé; Blecker, Christophe et alin Food Quality & Preference (2016)During the past few years, entomophagy has been increasing in significance. As insects are generally high in protein, they are principally considered as meat substitutes. Nevertheless, in Western ... [more ▼]During the past few years, entomophagy has been increasing in significance. As insects are generally high in protein, they are principally considered as meat substitutes. Nevertheless, in Western countries, meat substitute consumption is actually very low, principally due to food neophobia and poor sensory qualities in comparison with meat. In insect particular case, food neophobia is clearly high. To reduce insect food neophobia, previous studies suggest to insert invisible insect in food preparation and/or to associate them with known flavors. In this study, a survey on entomophagy perception and hedonic tests were realized to assess the level of sensory-liking of hybrid insect-based burgers (beef, lentils, mealworms and beef, mealworms and lentils). Participants’ overall liking of the four burgers differed between genders and was influenced by burger appearance and taste. Women clearly preferred beef burger appearance, whereas men preferred the appearance of beef and insect-based burgers. Concerning insect-based burger taste, participants (men and women) rated it intermediately, between that of the beef and lentil burger, with a preference for the mealworm and beef burger. Results also showed that people with previous entomophagy experience was limited but that they gave globally higher ratings to all preparations. In conclusion, insect tasting sessions are important to decrease food neophobia, as they encourage people to “take the first step” and become acquainted with entomophagy. Nevertheless, insect integration into Western food culture will involve a transitional phase with minced or powdered insects incorporated into ready-to-eat preparations, as people are not ready to add insects to their diets in “whole form.” [less ▲]Detailed reference viewed: 28 (6 ULg) Thermosensitivity of the sex differentiation process in the African catfish, Clarias gariepinus: Determination of the thermosensitive periodSanti, Saïdou ; Gennotte, Vincent ; Toguyeni, Aboubacar et alin Aquaculture (2016), 455Gonadal sex differentiation in gonochoristic fish is generally labile and under the control of two interacting processes: genetic sex determination (GSD) and environmental sex determination (ESD ... [more ▼]Gonadal sex differentiation in gonochoristic fish is generally labile and under the control of two interacting processes: genetic sex determination (GSD) and environmental sex determination (ESD). Numerous experimental studies deal with temperature induced-sex differentiation in teleosts, but none focused on the African catfish Clarias gariepinus. The aim of this study was to confirm the thermosensitivity of the sex differentiation process and to determine the thermosensitive period during the African catfish development. Fish were exposed to high temperature (36 °C) for 3 days at different periods during ontogenesis. The treatment was applied every 3 days from fertilization until 29 days post-hatching (dph). Before and after the thermal treatment, fish were reared at 28 °C. Gonadal development was histologically characterized on fish sampled at 10, 15, 20, 25, 35, 45, 55 and 70 dph. Our results demonstrated that the African catfish displays a thermosensitivity of the sex differentiation process, with a masculinizing effect of high temperature (36 °C). The most thermosensitive period extended from 6 to 8 dph. Fish batches exposed to 36 °C during this period showed a sex-ratio skewed towards the male phenotype, ranging from 58 to 100% (high inter-familial variability). The African catfish gonads (male and female) stayed histologically undifferentiated until 20 dph. Obvious signs of gonadal differentiation clearly appeared at 25 dph in females and at 45 dph in males. Variability in sex-ratios between progenies and in the response to thermal treatment suggests a role of minor genetic factors and interactions between genomic and environmental determinants in the expression of the sexual phenotype. Statement of relevance: 1. This paper provides novel methods to control African catfish Clarias gariepinus sex differentiation through high temperature exposure and then to produce all-male populations. 2. Our work underlines the possibility to significantly reduce high temperature (masculinizing effect) treatment period to 3 days and consequently increase survival rate of progenies after treatment. 3. This study also shows the inter-family variability of thermosensitivity on the sex differentiation process in Clarias gariepinus. [less ▲]Detailed reference viewed: 32 (8 ULg) Neural correlates of event clusters in past and future thoughts: How the brain integrates specific episodes with autobiographical knowledgeDemblon, Julie ; Bahri, Mohamed Ali ; D'Argembeau, Arnaud in NeuroImage (2016), 127When remembering the past or envisioning the future, events often come to mind in organized sequences or stories rather than in isolation from one another. The aim of the present fMRI study was to ... [more ▼]When remembering the past or envisioning the future, events often come to mind in organized sequences or stories rather than in isolation from one another. The aim of the present fMRI study was to investigate the neural correlates of such event clusters. Participants were asked to consider pairs of specific past or future events: in one condition, the two events were part of the same event cluster (i.e., they were thematically and/or causally related to each other), whereas in another condition the two events only shared a surface feature (i.e., their location); a third condition was also included, in which the two events were unrelated to each other. The results showed that the processing of past and future events that were part of a same cluster was associated with higher activation in the medial prefrontal cortex (PFC), rostrolateral PFC, and left lateral temporal and parietal regions, compared to the two other conditions. Furthermore, functional connectivity analyses revealed an increased coupling between these cortical regions. These findings suggest that largely similar processes are involved in organizing events in clusters for the past and the future. The medial and rostrolateral PFC might play a pivotal role in mediating the integration of specific events with conceptual autobiographical knowledge ‘stored’ in more posterior regions. Through this integrative process, this set of brain regions might contribute to the attribution of an overarching meaning to representations of specific past and future events, by contextualizing them with respect to personal goals and general knowledge about one's life story. [less ▲]Detailed reference viewed: 34 (7 ULg) compte rendu de : Stefano Valente, The Antiatticist. Introduction and Critical Edition, Berlin/Boston, De Gruyter. 2015.Rochette, Bruno in Anzeiger für die Altertumswissenschaft (2016)Detailed reference viewed: 6 (0 ULg) 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).Galie, Nazzareno; Humbert, Marc; Vachiery, Jean-Luc et alin European heart journal (2016), 37(1), 67-119Detailed reference viewed: 20 (0 ULg) High resolution characterization of the soil organic carbon depth profile in a soil landscape affected by erosionJague, Emilien; Sommer, Michael; Saby, Nicolas et alin Soil & Tillage Research (2016), 156Detailed reference viewed: 36 (5 ULg) Detecting urban road network accessibility problems using taxi GPS dataCui, JianXun; Liu, Feng; Janssens, Davy et alin Journal of Transport Geography (2016), 51Urban population growth and economic development have led to the creation of new communities, jobs and services at places where the existing road network might not cover or efficiently handle traffic ... [more ▼]Urban population growth and economic development have led to the creation of new communities, jobs and services at places where the existing road network might not cover or efficiently handle traffic. This generates isolated pockets of areas which are difficult to reach through the transport system. To address this accessibility problem, we have developed a novel approach to systematically examine the current urban land use and road network conditions as well as to identify poorly connected regions, using GPS data collected from taxis. This method is composed of four major steps. First, city-wide passenger travel demand patterns and travel times are modeled based on GPS trajectories. Upon this model, high density residential regions are then identified, and measures to assess accessibility of each of these places are developed. Next, the regions with the lowest level of accessibility among all the residential areas are detected, and finally the detected regions are further examined and specific transport situations are analyzed. By applying the proposed method to the Chinese city of Harbin, we have identified 20 regions that have the lowest level of accessibility by car among all the identified residential areas. A serious reachability problem to petrol stations has also been discovered, in which drivers from 92.6% of the residential areas have to travel longer than 30 min to refill their cars. Furthermore, the comparison against a baseline model reveals the capacity of the derived measures in accounting for the actual travel routes under divergent traffic conditions. The experimental results demonstrate the potential and effectiveness of the proposed method in detecting car-based accessibility problems, contributing towards the development of urban road networks into a system that has better reachability and more reduced inequity. [less ▲]Detailed reference viewed: 19 (1 ULg) Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanolDidone, Vincent ; Masson, Sébastien; Quoilin, Caroline et alin Addiction Biology (2016), 21(2), 387-396Repeated ethanol injections lead to a sensitization of its stimulant effects in mice. Some recent results argue against a role for ventral tegmental area (VTA) dopamine neurons in ethanol behavioral ... [more ▼]Repeated ethanol injections lead to a sensitization of its stimulant effects in mice. Some recent results argue against a role for ventral tegmental area (VTA) dopamine neurons in ethanol behavioral sensitization. The aim of the present study was to test whether in vivo ethanol locomotor sensitization correlates with changes in either basal- or ethanol evoked firing rates of dopamine neurons in vitro. Female Swiss mice were daily injected with 2.5 g/kg ethanol (or saline in the control group) for 7 days and their locomotor activity was recorded. At the end of the sensitization procedure, extracellular recordings were made from dopaminergic neurons in midbrain slices from these mice. Significantly higher spontaneous basal firing rates of dopamine neurons were recorded in ethanol-sensitized mice relative to control mice, but without correlations with the behavioral effects. The superfusion of sulpiride, a dopamine D2 antagonist, induced a stronger increase of dopamine neuron firing rates in ethanol-sensitized mice. This shows that the D2 feedback in dopamine neurons is preserved after chronic ethanol administration and argues against a reduced D2 feedback as an explanation for the increased dopamine neuron basal firing rates in ethanol-sensitized mice. Finally, ethanol superfusion (10–100 mM) significantly increased the firing rates of dopamine neurons and this effect was of higher magnitude in ethanol-sensitized mice. Furthermore, there were significant correlations between such a sensitization of dopamine neuron activity and ethanol behavioral sensitization. These results support the hypothesis that changes in brain dopamine neuron activity contribute to the behavioral sensitization of the stimulant effects of ethanol. [less ▲]Detailed reference viewed: 41 (14 ULg) SPICAM observations and modeling of Mars auroraeSoret, Lauriane ; Gérard, Jean-Claude ; Libert, Ludivine et alin Icarus (2016), 264Martian aurorae have been detected with the SPICAM instrument on board Mars Express both in the nadir and the limb viewing modes. In this study, we focus on three limb observations to determine both the ... [more ▼]Martian aurorae have been detected with the SPICAM instrument on board Mars Express both in the nadir and the limb viewing modes. In this study, we focus on three limb observations to determine both the altitudes and the intensities of the auroral emissions. The CO (a3P–X1R) Cameron bands between 190 and 270 nm, the CO Fourth Positive system (CO 4P) between 135 and 170 nm, the CO2+ doublet at 289 nm, the OI at 297.2 nm and the 130.4 nm OI triplet emissions have been identified in the spectra and in the time variations of the signals. The intensities of these auroral emissions have been quantified and the altitude of the strongest emission of the CO Cameron bands has been estimated to be 137 ± 27 km. The locations of these auroral events have also been determined and correspond to the statistical boundary of open-closed magnetic field lines, in cusp-like structures. The observed altitudes of the auroral emissions are reproduced by a Monte-Carlo model of electron transport in the Martian thermosphere for mono-energetic electrons between 40 and 200 eV. No correlation between electron fluxes measured in the upper thermosphere and nadir auroral intensity has been found. Here, we simulate auroral emissions observed both at the limb and at the nadir using electron energy spectra simultaneously measured with the ASPERA-3/ELS instrument. The simulated altitudes are in very good agreement with the observations. We find that predicted vertically integrated intensities for the various auroral emissions are overestimated, probably as a consequence of the inclination and curvature of the magnetic field line threading the aurora. However, the relative brightness of the CO and CO2+ emissions is in good agreement with the observations. [less ▲]Detailed reference viewed: 40 (12 ULg) Les exercices de contrôle moteur pour le traitement des lombalgies non-spécifiques aiguësDemoulin, Christophe in Cochrane Database of Systematic Reviews (Online) (2016)Traduction en Français du résumé de la revueDetailed reference viewed: 19 (1 ULg) Brentano, la théorie des catégories et la définition de la substanceBoccaccini, Federico in Etudes Philosophiques (2016)Detailed reference viewed: 24 (0 ULg) Displacement of an Electrically Charged Drop on a Vibrating BathBrandenbourger, Martin ; Vandewalle, Nicolas ; Dorbolo, Stéphane in Physical Review Letters (2016), 116Detailed reference viewed: 21 (2 ULg) COMPUTED TOMOGRAPHY AND MAGNITEC RESONANCE FINDINGS IN ATHLETES AT RISK FOR SUDDEN CARDIAC DEATHGHEKIERE, olivier; Nchimi Longang, Alain ; BIJNENES, Eric et alin Journal of the Belgian Society of Radiology (2016), 44Detailed reference viewed: 13 (2 ULg) Doped sol–gel films vs. powders TiO2: On the positive effect induced by the presence of a substrateLéonard, Géraldine ; Malengreaux, Charline; Melotte, Quentin et alin Journal of Environmental Chemical Engineering (2016), 4SiO2 and Ag–SiO2 doped TiO2 films and powders have been produced using a controlled sol–gel process. The dopant has been introduced using an alkoxysilane-functionalized ligand, with or without complexed ... [more ▼]SiO2 and Ag–SiO2 doped TiO2 films and powders have been produced using a controlled sol–gel process. The dopant has been introduced using an alkoxysilane-functionalized ligand, with or without complexed silver ions. The influence of dopants on physico-chemical properties of the catalysts is studied by XRD, TEM–EDX, DRUV–vis analyses in the case of powders, while GIXRD, XPS, profilometry, UV–vis absorption analyses have been used for thin films. The photocatalytic activity has been evaluated from the degradation of methylene blue under UV-A light in the presence of the different catalysts over a period of 24 h. The detailed comparison between powders and films highlights a surprising positive effect in the case of films due to the presence of the substrate. In the case of photocatalytic powders, the presence of SiO2 or Ag–SiO2 into the TiO2 matrix has a detrimental effect on the photocatalytic activity while the opposite tendency is observed in the case of films, with best activities obtained with Ag–SiO2 doping. Different factors, in particular crystallinity modification between powders and films, have been studied to explain these opposite behaviors. In the case of powders, crystallization is hindered by SiO2 and Ag particles incorporation into the TiO2 matrix, leading to a decrease of the photocatalytic activity. In the case of thin films, probably because of the presence of a substrate, crystallization is not influenced by the presence of SiO2 and Ag particles. Therefore, the latter ones can fully play their role of electron traps leading to an enhanced photocatalytic activity. [less ▲]Detailed reference viewed: 52 (11 ULg) Characterization of almond kernel oils of five almonds varieties cultivated in Eastern MoroccoHoumy, Nadia; Mansouri, F.; Benmoumen, A. et alin Cahiers Options Méditerranéennes (2016)This study focuses on characterization of almondkernel oils extrated mechanically from five sweet almond varieties (Marcona, Fournat, Ferragnes, Ferraduel and Beldi), cultivated in eastern Morocco. Oil ... [more ▼]This study focuses on characterization of almondkernel oils extrated mechanically from five sweet almond varieties (Marcona, Fournat, Ferragnes, Ferraduel and Beldi), cultivated in eastern Morocco. Oil content, physicochemical parameters, triacylglycerol and fatty acid compositions were determined. [less ▲]Detailed reference viewed: 8 (1 ULg) Prevention of Incisional Hernias by Prophylactic Mesh-augmented Reinforcement of Midline Laparotomies for Abdominal Aortic Aneurysm Treatment: A Randomized Controlled Trial.Muysoms, Filip E.; DETRY, Olivier ; Vierendeels, Tijl et alin Annals of surgery (2016), 263(4), 638-645BACKGROUND: The incidence of incisional hernias after abdominal aortic aneurysm repair is high. Prophylactic mesh-augmented reinforcement during laparotomy closure has been proposed in patients at high ... [more ▼]BACKGROUND: The incidence of incisional hernias after abdominal aortic aneurysm repair is high. Prophylactic mesh-augmented reinforcement during laparotomy closure has been proposed in patients at high risk of incisional hernia. METHODS: A multicenter randomized trial was conducted on patients undergoing elective abdominal aortic aneurysm repair through a midline laparotomy (Clinical.Trials.gov: NCT00757133). In the study group, retromuscular mesh-augmented reinforcement was performed with a large-pore polypropylene mesh (Ultrapro, width 7.5 cm). The primary endpoint was the incidence of incisional hernias at 2-year follow-up. RESULTS: Between February 2009 and January 2013, 120 patients were recruited at 8 Belgian centers. Patients' characteristics at baseline were similar between groups. Operative and postoperative characteristics showed no difference in morbidity or mortality. The cumulative incidence of incisional hernias at 2-year follow-up after conventional closure was 28% (95% confidence interval [CI], 17%-41%) versus 0% (95% CI, 0%-6%) after mesh-augmented reinforcement (P < 0.0001; Fisher exact test). The estimated "freedom of incisional hernia" curves (Kaplan-Meier estimate) were significantly different across study arms (chi = 19.5, P < 0.0001; Mantel-Cox test). No adverse effect related to mesh-augmented reinforcement was observed, apart from an increased mean time to close the abdominal wall for mesh-augmented reinforcement compared with the control group: 46 minutes (SD, 18.6) versus 30 minutes (SD, 18.5), respectively (P < 0.001; Mann-Whitney U test). CONCLUSIONS: Prophylactic retromuscular mesh-augmented reinforcement of a midline laparotomy in patients with abdominal aortic aneurysm is safe and effectively prevents the development of incisional hernia during 2 years, with an additional mean operative time of 16 minutes. [less ▲]Detailed reference viewed: 10 (3 ULg) Palindromic sequences generated from marked morphismsLabbé, Sébastien ; Pelantova, Editain European Journal of Combinatorics (2016), 51Detailed reference viewed: 6 (1 ULg) Physico-chemical properties and amino acid profiles of sap from Tunisian date palmMakhouf-Gafsi, Ines; Mokni-Ghribi, Abir; Brahim, Bchir et alin Scientia Agricola (2016), 73(1), 85-90Date palm sap (Phoenix dactylifera L.), also known as "legmi", is a fresh juice ex¬tracted from date palm trees. The present study aimed to elucidate the effects of collection time (at the beginning of ... [more ▼]Date palm sap (Phoenix dactylifera L.), also known as "legmi", is a fresh juice ex¬tracted from date palm trees. The present study aimed to elucidate the effects of collection time (at the beginning of the tapping period and after seven days of collection) on the amino acid profile and physico-chemical properties of date palm sap from both male and female trees. Dry matter, protein, amino acid, and sugar profiles were determined using the Kjeldahl method, High-Performance Liquid Chromatography (HPLC), and High-Performance Anion-Exchange Chro¬matography with Pulsed Amperometric Detection (HPAEC-PAD), respectively. Date palm sap from both male and female trees contained high levels of carbohydrates. HPLC analysis showed that this fraction was dominated by sucrose in the sap sample from female trees compared to that from male trees. Male date palm sap was noted to exhibit lower dry matter content than female date palm sap but higher protein, total polyphenol, ash, and amino acid contents. While the major essential amino acids in the sap from male trees consisted of valine and threonine, they were represented by lysine and phenylalanine in sap samples from female trees. Further, Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE) analysis showed the presence of a proteinic band of 30 kDa only for the sap from male trees. Taken together, the sap from both male and female date palm trees had a number of properties that are highly valued by the functional food industry. [less ▲]Detailed reference viewed: 30 (2 ULg) Sartre in Venedig: der Mann, der in die Kälte gingCormann, Grégory ; Viehöver, Vera in Bulletin d'Analyse Phénoménologique (2016), 11Detailed reference viewed: 39 (4 ULg) Photocatalytic decomposition of hydrogen peroxide over nanoparticles of TiO2 and Ni(II)-porphyrin doped TiO2: a relationship between activity and porphyrin anchoring modeTasseroul, Ludivine ; Pàez Martinez, Carlos ; Lambert, Stéphanie et alin Applied Catalysis B : Environmental (2016), 182The nickel tetra(4-carboxyphenyl)porphyrin (TCPPNi) was chimisorbed on Degussa P25 TiO2 at different concentrations. Diffuse reflectance spectroscopy in the UV/vis region, Fourier transform infrared ... [more ▼]The nickel tetra(4-carboxyphenyl)porphyrin (TCPPNi) was chimisorbed on Degussa P25 TiO2 at different concentrations. Diffuse reflectance spectroscopy in the UV/vis region, Fourier transform infrared spectroscopy and thermal gravimetry combined with differential scanning calorimetry measurements allowed the determination of the TCPPNi anchoring mode. At low TCPPNi concentrations, this anchoring on Degussa P25 TiO2 took place through all four carboxylic groups, while at higher concentrations the anchoring occurred through one or two carboxylic groups. For the firsttime,the effect of UV/vis light irradiation on the H2O2-degradation activity of TiO2 and TCPPNi-doped TiO2 was studied using the method of following the production of O2 by gas pressure monitoring. The activity of seven different catalysts was related to the TCPPNi anchoring mode and the percentage of TiO2 Degussa P25 coverage. An optimum degradation of H2O2 was observed for 0.0115 mol TCPPNi × g−1 P25. In that case, the TCPPNi was anchored through the four carboxylic groups, corresponding to a strong interaction with Degussa P25 TiO2. Moreover, the TCPPNi did not cover the surface completely, therefore allowing the light to reach and activate the TiO2. [less ▲]Detailed reference viewed: 46 (10 ULg) External Costs as Competitiveness Factors for Freight Transport — A State of the ArtMostert, Martine ; Limbourg, Sabine in Transport Reviews (2016)External costs have been a key issue in the last years of transport research. In Europe, this trend is in line with the political willingness to internalize externalities in transport pricing policies ... [more ▼]External costs have been a key issue in the last years of transport research. In Europe, this trend is in line with the political willingness to internalize externalities in transport pricing policies. This paper has two purposes. It first identifies the recent work achieved in the field of external costs of road and intermodal freight transport, where each paper is assessed in terms of its perspective (academic or project oriented), its objective (prescription, application, projection), the type of externality (air pollution, climate change, noise, accidents, congestion) and the type of cost (marginal, average, total) that is considered. The literature review reveals a gap in the development of generic mathematical functions for external costs of transport. The second objective of the paper is thus to highlight the usefulness of such functions by identifying the main parameters that influence freight transport competitiveness in terms of external costs, and by determining which of these parameters should be incorporated in further research works. [less ▲]Detailed reference viewed: 36 (7 ULg) HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapiesPeixoto, Paul; Blomme, Arnaud; Costanza, Brunella et alin Oncogene (2016)To date, the mutational status of EGFR and PTEN has been shown as relevant for favoring pro- or anti-tumor functions of STAT3 in human glioblastoma multiforme (GBM). We have screened genomic data from 154 ... [more ▼]To date, the mutational status of EGFR and PTEN has been shown as relevant for favoring pro- or anti-tumor functions of STAT3 in human glioblastoma multiforme (GBM). We have screened genomic data from 154 patients and have identified a strong positive correlation between STAT3 and HDAC7 expression. In the current work we show the existence of a subpopulation of patients overexpressing HDAC7 and STAT3 that has particularly poor clinical outcome. Surprisingly, the somatic mutation rate of both STAT3 and HDAC7 was insignificant in GBM comparing with EGFR, PTEN or TP53. Depletion of HDAC7 in a range of GBM cells induced the expression of tyrosine kinase JAK1 and the tumor suppressor AKAP12. Both proteins synergistically sustained the activity of STAT3 by inducing its phosphorylation (JAK1) and protein expression (AKAP12). In absence of HDAC7, activated STAT3 was responsible for significant imbalance of secreted pro-/anti-angiogenic factors. This inhibited the migration and sprouting of endothelial cells in paracrine fashion in vitro as well as angiogenesis in vivo. In a murine model of GBM, induced HDAC7-silencing decreased the tumor burden by threefold. The current data show for the first time that silencing HDAC7 can reset the tumor suppressor activity of STAT3, independently of the EGFR/PTEN/TP53 background of the GBM. This effect could be exploited to overcome tumor heterogeneity and provide a new rationale behind the development of specific HDAC7 inhibitors for clinical use. [less ▲]Detailed reference viewed: 23 (10 ULg) L'impôt sur les revenus des salariés et l'extranéité (1e partie)Docclo, Caroline in Journal des Tribunaux du Travail (2016)Detailed reference viewed: 47 (2 ULg) Electrophoretic deposition of hydroxyapatite and hydroxyapatite– alginate on rapid prototyped 3D Ti6Al4V scaffoldsOzhukil Kollath, Vinayaraj; Chen, Qiang; Mullens, Steven et alin Journal of Materials Science (2016), 51The advantage of using bioceramic particles coated on porous three-dimensional structures is still unexplored in the purpose of improving the osteoinduction of hybrid metallic scaffold implants in vivo ... [more ▼]The advantage of using bioceramic particles coated on porous three-dimensional structures is still unexplored in the purpose of improving the osteoinduction of hybrid metallic scaffold implants in vivo. In this study, we evaluate electrophoretic deposition (EPD) to coat porous Ti6Al4V scaffolds with hydroxyapatite (HA). Scaffolds were shaped in different open structures with a horizontal shift in fiber stacking. They were produced using three-dimensional fiber deposition method and were coated by EPD with HA powder (d10 = 1.7, d50 = 5.7 and d90 = 18 lm) suspended in ethanol or butanol at different concentration, DC voltage, and time. A composite HA–alginate was also used to coat the scaffolds. Alginate was used as a binder, and the coating properties (homogeneity, thickness, cracks, continuity, etc.) were compared to coatings obtained from pure HA suspensions. Voltage and time of deposition effects were studied between 10 and 140 V and 10 and 120 s, respectively. Coating thickness and density with respect to the depth of the porous structure were studied by observing cross sections using scanning electron microscopy and image processing analysis. HA–alginate combination resulted in a homogeneous and deeper dense layer of HA. This work also points to the characteristics of HA–alginate composite as a superior alternative to pure HA coating which needs an appropriate thermal treatment for adequate substrate adhesion. [less ▲]Detailed reference viewed: 21 (6 ULg) The role of personal goals in autonoetic experience when imagining future eventsLehner, Edith; D'Argembeau, Arnaud in Consciousness & Cognition (2016), 42Detailed reference viewed: 19 (4 ULg) The role of diet and exercise and of glucosamine sulfate in the prevention of knee osteoarthritis: Further results from the PRevention of knee Osteoarthritis in Overweight Females (PROOF) study.Runhaar, J.; DEROISY, Rita ; van Middelkoop, M. et alin Seminars in Arthritis & Rheumatism (2016), 45(4 Suppl), 42-48Background and objectives: The PRevention of knee Osteoarthritis in Overweight Females(PROOF) study (ISRCTN42823086) described a trend for a decrease in the incidence of kneeo steoarthritis (OA) by a ... [more ▼]Background and objectives: The PRevention of knee Osteoarthritis in Overweight Females(PROOF) study (ISRCTN42823086) described a trend for a decrease in the incidence of kneeo steoarthritis (OA) by a tailored diet and exercise program (DEP)or by oral glucosamine sulfate in women at risk for the disease, using a composite clinical and/or radiological outcome. The aim of this updated post-hoc analysis was to re-assess the results according to more precise techniques and take advantage of the 2 x 2 factorial design. Methods: A total of 407 overweight( BMI > or egal 27kg/m2) women of 50–60 years of age with no diagnosis of knee OA were randomized to: (1) noDEP + placebo(Control, N = 102), (2) DEP + placebo (DEP, N = 101), (3) glucosamine sulfate + no DEP (GS, N = 102), and (4) DEP + glucosamine sulfate (DEP + GS, N = 102) and followed for 2.5 years, with standardized postero-anterior, semiflexed (MTP) view knee radiographs at baseline and end of the study. DEP consisted of a tailored low fat and/or low caloric diet and easy to implement physical activities. Glucosamine was given as oral crystalline glucosamine sulfate 1500 mg once daily ,double-blinded vs. placebo. Incident knee OA was defined as radiographic progression of >1mm minimum joint space narrowing (mJSN)in the medial tibiofemoral compartment, as previously assessed by the visual (manual) technique and by a new semi-automated method. Logistic regression analysis was used t ocalculate the odds ratio for the effect of the interventions. Results: After 2.5 years, 11.8% of control subjects developed knee OA. This incidence was decreased with glucosamine sulfate, either alone or in combination with the DEP, but not by the DEP alone. Since there was no statistical interaction between treatments, the 2x2 factorial design allowed analysis of patients receiving glucosamine sulfate (N = 204) vs. those not receiving it (N= 203), similarly for those on the DEP (N = 203) or not (N = 204). Glucosamine sulfate significantly decreased the risk of developing knee OA: odds ratio (OR) = 0.41(95% CI: 0.20–0.85, P = 0.02) by the manual JSN assessment method and OR = 0.42 (95% CI:0.20–0.92, P =0.03) by the semi-automated technique. Conversely, there was no decrease in risk with the DEP. Conclusions: Glucosamine sulfate decreased the risk of developing radiographic knee OA over 2.5 years in overweight, middle-aged women at risk, as determined by medial mJSN progression. Conversely a tailored diet and exercise program exerted no preventive effect, possibly because of the lower than expected effect on weigh tloss. [less ▲]Detailed reference viewed: 29 (7 ULg) L'atlas à l'épreuve de l'image en mouvement (Warburg, Farocki, Didi-Huberman)Hagelstein, Maud ; Hamers, Jérémy in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (2016)Partant des travaux récents de Georges Didi-Huberman sur l’atlas d’images (A. Warburg) comme outil et support d’une nouvelle heuristique du montage, ce texte confronte l’installation Histoires de fantômes ... [more ▼]Partant des travaux récents de Georges Didi-Huberman sur l’atlas d’images (A. Warburg) comme outil et support d’une nouvelle heuristique du montage, ce texte confronte l’installation Histoires de fantômes pour grandes personnes (G. Didi-Huberman, A. Gisinger, 2012), composée pour partie d’images en mouvement, à la pensée de la table warburgienne comme lieu d’une perpétuelle reconfiguration et d’une nouvelle lisibilité du monde. Se pourrait-il en effet qu’une image en mouvement, prise d’ordinaire dans un continuum clos, se dote, à travers le montage, des mêmes potentialités critiques – c’est-à-dire d’un même pouvoir inquiétant – que l’image fixe offerte au déambulateur de l’atlas ? [less ▲]Detailed reference viewed: 95 (9 ULg) Fast Atmospheric Plasma Deposition of Bio-Inspired Catechol/Quinone-Rich Nanolayers to Immobilize NDM-1 Enzymes for Water TreatmentMauchauffé, Rodolphe; Bonot, Sébastien; Moreno-Couranjou, Maryline et alin Advanced Materials Interfaces (2016), 3(8), 101002Detailed reference viewed: 11 (1 ULg) Postmodernité et psychothérapie : Quelques croisements entre les travaux de Sami-Ali et ceux de Deleuze et FoucaultEnglebert, Jérôme in Psychosomatique Relationnelle (2016), 5(1), Detailed reference viewed: 37 (7 ULg) Competing effects of volume change and water uptake on the water retention behaviour of a compacted MX-80 bentonite/sand mixtureGatabin, Claude; Talandier, Jean; Collin, Frédéric et alin Applied Clay Science (2016), 121-122Bentonite-based materials have been studied as potential barriers for the geological disposal of radioactive waste. In this context, the hydro-mechanical behaviour of the engineered barrier is first ... [more ▼]Bentonite-based materials have been studied as potential barriers for the geological disposal of radioactive waste. In this context, the hydro-mechanical behaviour of the engineered barrier is first characterized by free swelling conditions (as a consequence of the progressive filling of technological gaps) followed by constant volume conditions. This paper presents an experimental study conducted in order to characterize the water retention behaviour of a compacted MX-80 bentonite/sand mixture. The water retention properties upon wetting were investigated under both free swelling and constant volume conditions. In the high suction range, the water content was not influenced by the imposed volume constraints. On the contrary, swelling significantly affected the water retention behaviour at low suctions, and the quantity of water stored was higher under free swelling conditions than it was under prevented swelling. In this case, competing effects between bentonite swelling and water uptake did not lead to an increase of the degree of saturation upon wetting, as it was observed for samples wetted under constant volume conditions. The influence of the very strong hydro-mechanical coupling is further discussed. [less ▲]Detailed reference viewed: 54 (8 ULg) Adaptation posologique des médicaments et fonction rénale : Quel(s) estimateur(s) faut-il choisir?DELANAYE, Pierre ; Flamant, M; CAVALIER, Etienne et alin Néphrologie & Thérapeutique (2016), 12(1), 18-31Le choix de la formule d’estimation du de´ bit de filtration glomérulaire (DFG) a utiliser pour l’adaptation posologique fait encore de´ bat, principalement entre la formule de Cockcroft et les équations ... [more ▼]Le choix de la formule d’estimation du de´ bit de filtration glomérulaire (DFG) a utiliser pour l’adaptation posologique fait encore de´ bat, principalement entre la formule de Cockcroft et les équations plus récentes, MDRD (pour Modified Diet in Renal Disease) et CKD-EPI (pour Chronic Kidney Disease Epidemiology). Les arguments mis en avant en faveur de l’utilisation de la formule de Cockcroft sont : qu’elle a été préférentiellement utilisée pour décider des adaptations posologiques avant la mise sur le marché des médicaments, qu’elle permettrait une meilleure prédiction du risque de survenue des effets indésirables a l’accumulation des médicaments, qu’elle permettrait de limiter le surdosage médicamenteux chez la personne âgée. Dans cet article d’opinion, nous discutons les faiblesses de l’argumentaire des partisans du maintien de l’utilisation de la formule de Cockcroft dans le contexte de l’adaptation posologique, ainsi que les limites et le manque de fiabilité de cette formule. Nous soutenons la recommandation de la Haute Autorité de sante´ (HAS) sur l’utilisation systématique, en 2015, de l’équation CKD-EPI pour l’estimation du DFG. Lorsque le DFG est e´ value´ dans le but d’adapter la posologie d’un médicament, la désindexation de la surface corporelle est préférable. Compte tenu des difficultés d’estimation du DFG chez la personne âgée et chez les individus a gabarit hors norme, nous recommandons d’utiliser en priorité dans ces populations, des médicaments pour lesquels un suivi pharmacologique est disponible, ou d’avoir recours à une méthode de référence de mesure du DFG. [less ▲]Detailed reference viewed: 25 (3 ULg) Parsimonious time series clustering using P-splinesIorio, Carmela; Frasso, Gianluca ; D’Ambrosio, Antonio et alin Expert Systems with Applications (2016)Abstract We introduce a parsimonious model-based framework for clustering time course data. In these applications the computational burden becomes often an issue due to the large number of available ... [more ▼]Abstract We introduce a parsimonious model-based framework for clustering time course data. In these applications the computational burden becomes often an issue due to the large number of available observations. The measured time series can also be very noisy and sparse and an appropriate model describing them can be hard to define. We propose to model the observed measurements by using P-spline smoothers and then to cluster the functional objects as summarized by the optimal spline coefficients. According to the characteristics of the observed measurements, our proposal can be combined with any suitable clustering method. In this paper we provide applications based on non-hierarchical clustering algorithms. We evaluate the accuracy and the efficiency of our proposal by simulations and by analyzing two real data examples. [less ▲]Detailed reference viewed: 13 (1 ULg) Adaptation et neurosciences I : craintes, société, méthodologie, finalitéDesseilles, Martin in Santé Mentale au Québec (2016), XL(3), 209-221Cetarticleestlepremierdedeuxarticlesexplorantlesliensbidirection- nels entre le concept d’adaptation et celui de neurosciences. Nous verrons tout d’abord dans cet article que les neurosciences peuvent ... [more ▼]Cetarticleestlepremierdedeuxarticlesexplorantlesliensbidirection- nels entre le concept d’adaptation et celui de neurosciences. Nous verrons tout d’abord dans cet article que les neurosciences peuvent être perçues comme ambi- tieuses et toutes-puissantes oscillant entre un danger réductionniste et déshuma- nisant ou bien cristallisant certains fantasmes de maîtrise. Nous verrons ensuite que la société s’adapte aux neurosciences en intégrant certaines méthodologies et certaines découvertes dans des domaines très variés, au point que nous pouvons nous questionner sur la neurosociété de demain. Ensuite nous verrons que la méthodologie des neurosciences est elle-même fréquemment remise en question et nécessite que chacun en connaisse les limites sans s’en tenir aux seules pro- messes. Après cela, nous verrons que l’adaptation vue comme une promesse d’un but déterminé et fini peut s’avérer rassurante mais est surtout improbable. [less ▲]Detailed reference viewed: 53 (1 ULg) Real-time remedial action against aperiodic small signal rotor angle instabilityWeckesser, Johannes ; Jóhannsson, Hjörtur; Østergaard, Jacobin IEEE Transactions on Power Systems (2016), 31(1), 387-396This paper presents a method that in real-time determines remedial actions, which restore stable operation with respect to aperiodic small signal rotor angle stability (ASSRAS) when insecure or unstable ... [more ▼]This paper presents a method that in real-time determines remedial actions, which restore stable operation with respect to aperiodic small signal rotor angle stability (ASSRAS) when insecure or unstable operation has been detected. An ASSRAS assessment method is used to monitor the stability boundary for each generator in real-time. The ASSRAS boundary represents the condition when a generator reaches the maximum steady state active power injection. The proposed control method exploits analytically derived expressions for the ASSRAS boundary and other characteristic curves in the injection impedance plane to determine an active power redispatch among selected generators to restore stable and secure operation. Since the method is purely based on analytically derived expression, the computation of the remedial actions is fast and well suited for real-time operation. The method was tested on the IEEE 14-bus and the Nordic32 test systems where results show that the method can efficiently determine the required active power redispatch to avoid an imminent instability. [less ▲]Detailed reference viewed: 8 (0 ULg) Proposal for standardized ultrasound descriptors of abnormally invasive placenta (AIP)Collins, Sally; Anna, Ashcroft; Braun, Thorsten et alin Ultrasound in Obstetrics & Gynecology (2016)Detailed reference viewed: 16 (1 ULg) Risk assessment of soil compaction in the Walloon region in BelgiumD'Or, Dimitri; Destain, Marie-France in Mathematical Geosciences (2016)It is well known that soil compaction affects root growth and disrupts the activity of soil microfauna and microorganisms, resulting in yield loss. With the more intensive use of heavy machines in ... [more ▼]It is well known that soil compaction affects root growth and disrupts the activity of soil microfauna and microorganisms, resulting in yield loss. With the more intensive use of heavy machines in agriculture and forestry, the risk of soil compaction is increasing. In this study, precompression stress (Pc) was chosen as an indicator of the susceptibility of soils to compaction and was calculated using pedotransfer functions (PTFs). PTFs involve eight variables related to the hydraulic and mechanical behaviour of soils: organic matter content; bulk density; air capacity; available water capacity; non-plant available water capacity; saturated hydraulic conductivity; cohesion; and angle of internal friction. Combining these PTFs with geostatistics and Monte Carlo simulations, Pc maps were produced at the regional scale for Wallonia in Belgium, accompanied by uncertainty quantification maps. These maps were then used to produce compaction risk maps based on common scenarios. The results showed that the modal Pc map was coherent with the spatial distribution of the main variables, namely soil texture and organic matter content. The risk maps enabled areas with a compaction risk in both agricultural and forestry contexts to be identified. These maps could be useful in drawing up soil protection measures and policies. [less ▲]Detailed reference viewed: 32 (11 ULg) Exploring the bacterial diversity of Belgian steak tartare using metagenetics and qPCR analysisDelhalle, Laurent ; Korsak Koulagenko, Nicolas ; Taminiau, Bernard et alin Journal of Food Protection (2016), 79(2), 200-229Steak tartare is a popular meat dish in Belgium. It is prepared with raw ground minced beef and eaten with sauce, vegetables, and spiced. Since it contains raw meat, steak tartare is highly prone to ... [more ▼]Steak tartare is a popular meat dish in Belgium. It is prepared with raw ground minced beef and eaten with sauce, vegetables, and spiced. Since it contains raw meat, steak tartare is highly prone to bacterial spoilage. The objective of this study was to explore the bacterial flora diversity in steak tartare in Belgium according to the source and to determine which bacteria are able to grow during the shelf life. A total of 58 samples from butchers’ shops, restaurants, sandwich shops and supermarkets were collected. These samples were analyzed using 16S rDNA metagenetics, a classical microbiological technique, and quantitative real-time PCR (qPCR) targeting the Lactobacillus genus. Samples were analyzed at the beginning and at the end of their shelf life, except for those from restaurants and sandwich shops analyzed only at the purchase date. Metagenetic analysis identified up to 180 bacterial species and 90 genera in some samples. But only seven bacterial species were predominant in the samples, depending on the source: Brochothrix thermosphacta, Lactobacillus algidus, Lactococcus piscium, Leuconostoc gelidum, Photobacterium kishitani, Pseudomonas spp. and Xanthomonas oryzae. With this work, an alternative method is proposed to evaluate the total flora in food samples based on the number of reads from metagenetic analysis and the results of qPCR. The degree of underestimation of aerobic plate counts (APCs) at 30°C estimated with the classical microbiology method was demonstrated in comparison with the proposed culture independent method. Compared to culture-based methods, metagenetic analysis combined with qPCR targeting Lactobacillus provides valuable information for characterizing the bacterial flora of raw meat. [less ▲]Detailed reference viewed: 193 (32 ULg) Migration, prostitution and the representation of the black female subject in Nigerian video films about ItalyJedlowski, Alessandro in Journal of Italian Cinema and Media Studies (2016), 4(1), 9-23Much contemporary images of black women in Italian media are marked by the legacy of colonialist propaganda and tend to perpetuate a representation of black women as passive eroticized objects of the ... [more ▼]Much contemporary images of black women in Italian media are marked by the legacy of colonialist propaganda and tend to perpetuate a representation of black women as passive eroticized objects of the white male gaze. In this sense, Ponzanesi’s call for ‘new and less biased representations, which could help to assess the multiple subject positions that black identities now occupy’ (2005: 179) is still relevant. This article responds to this call by analyzing two Nigerian video films that thematize migration and prostitution trafficking in Italy. By highlighting the complexity of the processes of ‘subjectivation’ taking place throughout the migratory process, these videos invite their viewers to look at the postcolonial subject’s responsibility in shaping the world in which s/he lives, and offer a representation of the black female subject able to go beyond the voyeuristic attitude that characterize much of the existing contemporary Italian visual culture about this topic. [less ▲]Detailed reference viewed: 103 (2 ULg) Domain Decomposition Methods for Time-Harmonic Electromagnetic Waves with High Order Whitney FormsMarsic, Nicolas ; Waltz, Caleb; Lee, Jin-Fa et alin IEEE Transactions on Magnetics (2016), 52(3), Classically, domain decomposition methods (DDM) for time-harmonic electromagnetic wave propagation problems make use of the standard, low order, Nédélec basis functions. This paper analyzes the ... [more ▼]Classically, domain decomposition methods (DDM) for time-harmonic electromagnetic wave propagation problems make use of the standard, low order, Nédélec basis functions. This paper analyzes the convergence rate of DDM when higher order finite elements are used for both volume and interface discretizations, in particular when different orders are used in the volume and on the interfaces. [less ▲]Detailed reference viewed: 23 (5 ULg) Existence of two groups of Staphylococcus aureus strains isolated from bovine mastitis based on biofilm formation, intracellular survival, capsular profile and agr-typing.Bardiau, Marjorie ; Caplin, Jonathan; Detilleux, Johann et alin Veterinary microbiology (2016), 185Staphylococcus (S.) aureus is recognised worldwide as an important pathogen causing contagious acute and chronic bovine mastitis. Chronic mastitis account for a significant part of all bovine cases and ... [more ▼]Staphylococcus (S.) aureus is recognised worldwide as an important pathogen causing contagious acute and chronic bovine mastitis. Chronic mastitis account for a significant part of all bovine cases and represent an important economic problem for dairy producers. Several properties (biofilm formation, intracellular survival, capsular expression and group agr) are thought to be associated with this chronic status. In a previous study, we found the existence of two groups of strains based on the association of these features. The aim of the present work was to confirm on a large international and non-related collection of strains the existence of these clusters and to associate them with case history records. In addition, the genomes of eight strains were sequenced to study the genomic differences between strains of each cluster. The results confirmed the existence of both groups based on capsular typing, intracellular survival and agr-typing: strains cap8-positive, belonging to agr group II, showing a low invasion rate and strains cap5-positive, belonging to agr group I, showing a high invasion rate. None of the two clusters were associated with the chronic status of the cow. When comparing the genomes of strains belonging to both clusters, the genes specific to the group "cap5-agrI" would suggest that these strains are better adapted to live in hostile environment. The existence of these two groups is highly important as they may represent two clusters that are adapted differently to the host and/or the surrounding environment. [less ▲]Detailed reference viewed: 16 (2 ULg) Reassessment of the acrylamide risk: Belgium as a case-studyClaes, Wendie; De Meulenaer, Bruno; Huyghebaert, André et alin Food Control (2016), 59Acrylamide is a food process contaminant with carcinogenic and genotoxic properties. As a result of intensive research, numerous mitigation initiatives to prevent its formation were suggested and various ... [more ▼]Acrylamide is a food process contaminant with carcinogenic and genotoxic properties. As a result of intensive research, numerous mitigation initiatives to prevent its formation were suggested and various of them were implemented in the food chain. To evaluate if the mitigation strategies applied were significant, a comparison was made between two time periods (2002e2007 versus 2008e2013) in terms of acrylamide food levels and dietary exposure in Belgian. The most important changes observed are a significant decrease of the acrylamide content in potato crisps and gingerbread, and a significant increase in (instant) coffee. Additionally, the acrylamide content of breakfast cereals, bread and rolls, chocolate and baby biscuits showed a downward trend, whereas for coffee substitute and ready-to-eat French fries (mainly obtained from catering facilities), an upward, although not significant, trend was observed. These changes resulted in only a slight, but insignificant decline of the overall dietary exposure of adults, adolescents and children. The mean and P95 intake estimated in the 2008e2013 period for these consumer groups corresponded to margins of exposure (MOE) ranging between 515 and 236 and between 155 and 71, respectively, when based on the endpoint for neoplastic effects (BMDL10 ¼ 0.17 mg/kg bw per day). Such low MOE values indicate that acrylamide remains an issue for public concern, requiring renewed attention. [less ▲]Detailed reference viewed: 45 (3 ULg) The effect of insulin on plasma glucose concentrations, expression of hepatic glucose transporters and key gluconeogenic enzymes during the perinatal period in broiler chickensFranssens, L.; Lesuisse, J.; Wang, Yuan et alin General and Comparative Endocrinology (2016)Chickens have blood glucose concentrations that are twofold higher than those observed in mammals. Moreover, the insulin sensitivity seems to decrease with postnatal age in both broiler and layer chickens ... [more ▼]Chickens have blood glucose concentrations that are twofold higher than those observed in mammals. Moreover, the insulin sensitivity seems to decrease with postnatal age in both broiler and layer chickens. However, little is known about the response of insulin on plasma glucose concentrations and mRNA abundance of hepatic glucose transporters 1, 2, 3, 8, 9 and 12 (GLUT1, 2, 3, 8, 9 and 12) and three regulatory enzymes of the gluconeogenesis, phosphoenolpyruvate carboxykinase 1 and 2 (PCK1 and 2) or fructose-1,6-biphosphatase 1 (FBP1) in chicks during the perinatal period. In the present study, broiler embryos on embryonic day (ED)16, ED18 or newly-hatched broiler chicks were injected intravenously with bovine insulin (1. μg/g body weight (BW)) to examine plasma glucose response and changes in hepatic mRNA abundance of the GLUTs, PCK1 and 2 and FBP1. Results were compared with a non-treated control group and a saline-injected sham group. Plasma glucose levels of insulin-treated ED18 embryos recovered faster from their minimum level than those of insulin-treated ED16 embryos or newly-hatched chicks. In addition, at the minimum plasma glucose level seven hours post-injection (PI), hepatic GLUT2, FBP1 and PCK2 mRNA abundance was decreased in insulin-injected embryos, compared to sham and control groups, being most pronounced when insulin injection occurred on ED16. © 2015 Elsevier Inc. [less ▲]Detailed reference viewed: 13 (1 ULg) Strain-Engineered Multiferroicity in Pnma NaMnF3 FluoroperovskiteGarcia Castro, Andrés Camilo ; Bousquet, Eric ; Romero, Aldo H.in Physical Review Letters (2016)Detailed reference viewed: 16 (1 ULg)