References of "Scientific journals"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailFires of Pianura: The Antidump Struggle in the Western Outskirt of Naples
De Biase, Marco ULg

in Capitalism, Nature, Socialism (2015), 26(1), 39-58

This ethnographic study aimed at analyzing the rebellion in Pianura, which took place between December 2007 and January 2009 when Naples' streets were covered with rubbish. It was a violent protest ... [more ▼]

This ethnographic study aimed at analyzing the rebellion in Pianura, which took place between December 2007 and January 2009 when Naples' streets were covered with rubbish. It was a violent protest involving some 40.000 people who wanted to object to the reopening of the old dump of Pianura, one of the most toxic in Europe and no longer in use. The fear for their own life, the desperation of local population, and the anger after being attacked by the police during pacific protest gave origin to a real urban guerrilla targeting the political system. This article aims to go beyond the dominant narration of the events developed by the media and the authorities, which interpreted the uprising of Pianura in terms of Nimby (Not in my back yard), and as a mere manifestation of violence that was carried out by a group of extremists. On the contrary, it will be argued that the anti-dump struggle of Pianura, in its diverse forms, was animated by a radical critique of a specific model of local and national development (Gramsci 2007; Della Porta 2006). In order to support this argument the context of Pianura and the various mobilizations set up by the local population are analysed in this article. In addition, the heterogeneous and fragmented nature of the movement is explained through Bayat’s (1997; 2000) concept of “street politics” and that of “rebel bricolage” inspired by the work of Levi-Strauss (1966). More in detail, the analysis is focused on the effects of the “waste politics” on the body of the protesters, which became an important tool of resistance and an instrument to claim fundamental rights (Fassin, Memmi 2004). Finally, this article investigates the role of some groups of ultrà (football supporters) who actively participated in the demonstrations, and their relationship with the criminalizing discourses that were constructed to discredit the struggle. [less ▲]

Detailed reference viewed: 13 (3 ULg)
Full Text
Peer Reviewed
See detailAlexandre VI Borgia, le pape de la débauche
Marchandisse, Alain ULg

in Historia (2015), (Spécial 22),

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailStakeholder incentives and aid effectiveness: A case study in the health district of Kayes in Mali
Devahive, Eva; Paul, Elisabeth ULg; Samaké, Salif et al

in Journal of Development Studies (2015)

This case study analyses how far donors implement aid effectiveness principles at health district level in Mali, and why. It shows that not all aid effectiveness principles are implemented at a similar ... [more ▼]

This case study analyses how far donors implement aid effectiveness principles at health district level in Mali, and why. It shows that not all aid effectiveness principles are implemented at a similar degree. Most projects have limited impact on health services, but many programmes supported by donors offer positive opportunities for health system strengthening. The representations of different categories of stakeholders diverge – notably, regarding the role of different actors in service provision. A number of consistent strategic logics influence actors’ behaviour. We show that while many donors have committed at global level to respect aid effectiveness principles, implementation lags behind. [less ▲]

Detailed reference viewed: 51 (8 ULg)
Full Text
Peer Reviewed
See detailRitournelles et territoires professionnels. Le cas des conseillers emploi
Orianne, Jean-François ULg

in Langage et Société (2015), 151

L’objectif de ce texte est d’utiliser le concept de ritournelle pour analyser la formation d’un groupe professionnel dans le champ des politiques d’emploi en Belgique : les conseillers emploi du FOREM ... [more ▼]

L’objectif de ce texte est d’utiliser le concept de ritournelle pour analyser la formation d’un groupe professionnel dans le champ des politiques d’emploi en Belgique : les conseillers emploi du FOREM. L’auteur commence par définir et opérationnaliser le concept, emprunté à Deleuze et Guattari, en suivant les apports des théories de la communication réflexive. Il esquisse brièvement le contexte politique et institutionnel au sein duquel le groupe professionnel apparaît. Ensuite, il analyse trois ritournelles professionnelles, trois procédés de territorialisation des identités professionnelles des conseillers emploi. Il précise, en conclusion, la complémentarité du concept de ritournelle avec celui de rhétorique professionnelle. [less ▲]

Detailed reference viewed: 73 (22 ULg)
Full Text
See detailCompte rendu de Ulrich Herbert, Geschichte Deutschlands im 20. Jahrhundert
Brüll, Christoph ULg

in Wissenschaftlicher Literaturanzeiger [=WLA] (2015)

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailL'ordre public, la révision au fond et la légalisation: bref commentaire de la circulaire du 14 janvier 2015 relative à la légalisation
Wautelet, Patrick ULg; Verhellen, Jinske

in Revue Internationale de Droit Privé = Tijdschrift voor Internationaal Privaatrecht (2015), 14(1), 142-147

Le SPF Affaires Etrangères a adopté en janvier 2015 une nouvelle circulaire relative à la légalisation. Au premier regard, l'adoption de cette nouvelle circulaire permet de tenir compte de l'entrée en ... [more ▼]

Le SPF Affaires Etrangères a adopté en janvier 2015 une nouvelle circulaire relative à la légalisation. Au premier regard, l'adoption de cette nouvelle circulaire permet de tenir compte de l'entrée en vigueur du Code consulaire. Le chapitre 7 de ce Code est en effet consacré à la légalisation et à l'examen des documents étrangers. Il indique quelle autorité est compétente pour procéder à la légalisation d'un document (art. 33) et confirme la pratique antérieure des 'remarques' pouvant être apposées sur un acte étranger lorsqu'un doute sérieux existe sur l'authenticité de l'acte ou sur l'authenticité de son contenu (art. 34). Tous ces textes font référence à l'article 30 du Code de droit international privé, disposition qui constitue le socle de base dans ce domaine. A bien y regarder la nouvelle circulaire introduit néanmoins deux innovation importantes bien que singulières. Ces deux innovations pourraient avoir comme effet d'empêcher l'utilisation d'un acte étranger en Belgique. La présente contribution s'interroge de manière critique sur ces deux innovations en questionnant tant leur pertinence que leur efficacité. [less ▲]

Detailed reference viewed: 24 (0 ULg)
Full Text
See detailLaTeX, un peu, beaucoup (7. Tableaux (encore))
Dupont, Pascal ULg

in Losanges (2015), 28

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailCrosstalk between intracellular and extracellular signals regulating interneuron production migration and integration into the cortex
Peyre, Elise ULg; Gomes Da Silva, Carla ULg; Nguyen, Laurent ULg

in Frontiers in Cellular Neuroscience (2015)

During embryogenesis, cortical interneurons are generated by ventral progenitors located in the ganglionic eminences of the telencephalon. They travel along multiple tangential paths to populate the ... [more ▼]

During embryogenesis, cortical interneurons are generated by ventral progenitors located in the ganglionic eminences of the telencephalon. They travel along multiple tangential paths to populate the cortical wall. As they reach this structure they undergo intracortical dispersion to settle in their final destination. At the cellular level, migrating interneurons are highly polarized cells that extend and retract processes using dynamic remodeling of microtubule and actin cytoskeleton. Different levels of molecular regulation contribute to interneuron migration. These include: 1/ Extrinsic guidance cues distributed along migratory streams that are sensed and integrated by migrating interneurons; 2/ Intrinsic genetic programs driven by specific transcription factors that grant specification and set the timing of migration for different subtypes of interneurons; 3/ Adhesion molecules and cytoskeletal elements/regulators that transduce molecular signalings into coherent movement. These levels of molecular regulation must be properly integrated by interneurons to allow their migration in the cortex. The aim of this review is to summarize our current knowledge of the interplay between microenvironmental signals and cell autonomous programs that drive cortical interneuron porduction, tangential migration, and intergration in the developing cerebral cortex. [less ▲]

Detailed reference viewed: 16 (10 ULg)
Full Text
Peer Reviewed
See detailGestion implantaire de l'édentement unitaire dans le secteur esthétique : une approche visant à optimiser les tissus. Partie I : aspect chirurgical
LAMBERT, France ULg

in Réalites Cliniques : Revue Européenne d'Odontologie (2015), 26(n°1),

Nous sommes tous bien conscients de la problématique liée au remodelage osseux après extraction dentaire, en particulier dans la zone esthétique. Les conséquences cliniques sont telles que le recours à ... [more ▼]

Nous sommes tous bien conscients de la problématique liée au remodelage osseux après extraction dentaire, en particulier dans la zone esthétique. Les conséquences cliniques sont telles que le recours à des techniques de régénération tissulaire est souvent nécéssaire pour la pose de l'implant et pour assurer des résultats esthétiques. Cet article vise à démontrer l'efficacité d'un protocole d'optimisation tissulaire basé sur la préservation du capital osseux et sur l'optimisation des tissus gingivaux lors d'une extraction dentaire dans la zone esthétique. L'objectif de cet article est de suggérer un processus décisionnel en matière de technique chirurgicale, reposant d'une part sur l'examen clinique initial et, d'autre part, sur une excellente compréhension du concept biologique. [less ▲]

Detailed reference viewed: 7 (3 ULg)
Full Text
Peer Reviewed
See detailVeno-venous extracorporeal CO2 removal improves pulmonary hemodynamics in a porcine ARDS model
MORIMONT, Philippe ULg; GUIOT, Julien ULg; Desaive, Thomas ULg et al

in Acta Anaesthesiologica Scandinavica (2015)

BACKGROUND: Protective lung ventilation is recommended in patients with acute respiratory distress syndrome (ARDS) to minimize additional injuries to the lung. However, hypercapnic acidosis resulting from ... [more ▼]

BACKGROUND: Protective lung ventilation is recommended in patients with acute respiratory distress syndrome (ARDS) to minimize additional injuries to the lung. However, hypercapnic acidosis resulting from ventilation at lower tidal volume enhances pulmonary hypertension and might induce right ventricular (RV) failure. We investigated if extracorporeal veno-venous CO2 removal therapy could have beneficial effects on pulmonary circulation and RV function. METHODS: This study was performed on an experimental model of ARDS obtained in eight anaesthetized pigs connected to a volume-cycled ventilator. A micromanometer-tipped catheter was inserted into the main pulmonary artery and an admittance micromanometer-tipped catheter was inserted into the right ventricle. RV-arterial coupling was derived from RV pressure-volume loops. ARDS was obtained by repeated bronchoalveolar lavage. Protective ventilation was then achieved, and the pigs were connected to a pump-driven extracorporeal membrane oxygenator (PALP, Maquet, Germany) in order to achieve CO2 removal. RESULTS: ARDS induced severe hypercapnic acidosis. Systolic pulmonary artery pressure significantly increased from 29.6 ± 1.8 to 43.9 ± 2.0 mmHg (P < 0.001). After the PALP was started, acidosis was corrected and normocarbia was maintained despite protective ventilation. Pulmonary artery pressure significantly decreased to 31.6 ± 3.2 mmHg (P < 0.001) and RV-arterial coupling significantly improved (RV-arterial coupling index = 1.03 ± 0.33 vs. 0.55 ± 0.41, P < 0.05). CONCLUSION: Veno-venous CO2 removal therapy enabled protective ventilation while maintaining normocarbia during ARDS. CO2 removal decreased pulmonary hypertension and improved RV function. This technique may be an effective lung- and RV-protective adjunct to mechanical ventilation. [less ▲]

Detailed reference viewed: 20 (4 ULg)
Full Text
Peer Reviewed
See detailHigher-Moment Risk Exposures in Hedge Funds
Lambert, Marie ULg; Hübner, Georges ULg; Papageorgiou, Nicolas

in European Financial Management (2015), 21(2), 236-264

This paper singles out the key roles of US equity skewness and kurtosis in the hedge fund return generating process. We propose a conditional higher-moment model with location, trading, and higher-moment ... [more ▼]

This paper singles out the key roles of US equity skewness and kurtosis in the hedge fund return generating process. We propose a conditional higher-moment model with location, trading, and higher-moment factors to describe the dynamics of the equity hedge, event-driven, relative value, and fund of funds styles. If the volatility, skewness, and kurtosis implied in US options are used by fund managers as instruments to anticipate market movements, managers should adjust their market exposure in response to variations in these moments. We indeed show that higher-moment premia improve the conditional asset pricing model across all hedge fund styles. [less ▲]

Detailed reference viewed: 90 (20 ULg)
Full Text
Peer Reviewed
See detailConcordance between muscle mass assessed by bioelectrical impedance analysis and by dual energy X-ray absorptionmetry among elderly people: a cross-sectional study
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Dardenne, Nadia ULg et al

in BMC Musculoskeletal Disorders (2015), 16(1), 60-67

BACKGROUND: Besides magnetic resonance imaging, dual energy X-ray absorptiometry (DXA) seems the most reliable tool to evaluate body composition and is often considered as the gold standard in clinical ... [more ▼]

BACKGROUND: Besides magnetic resonance imaging, dual energy X-ray absorptiometry (DXA) seems the most reliable tool to evaluate body composition and is often considered as the gold standard in clinical practice. Bioelectrical impedance analysis (BIA) could provide a simpler, portative, and less expensive alternative. Because the body composition assessment by BIA is device-dependent, the aim of this study was to appraise the concordance between the specific bioelectrical impedance device InBody S10 and DXA for the body composition evaluation. METHODS: Body composition, included appendicular lean mass divided by height squared (ALM/ht2) was measured by DXA (Hologic QDR Discovery device) and by BIA (InBody S10 Biospace device). Agreement between tools was assessed by means of the Bland Altman method and reliability was determined using the IntraClass Coefficient (ICC). ICC was also computed to assess the reliability of the test-retest performed by the same operator or by two different ones. RESULTS: A total of 219 subjects were enrolled in this study (mean age: 43.7 +/- 19.1 years old, 51.6% of women). For the ALM/ht2, reliability of the test-retest of the BIA was high with an ICC of 0.89 (95%CI: 0.86-0.92) when performed by the same operator and an ICC of 0.77 (95%CI: 0.72-0.82) when performed by two different operators. Agreement between ALM/ht2 assessed by DXA and BIA was low (ICC = 0.37 (95%CI: 0.25-0.48)). Mean ALM/ht2 was 9.19 +/- 1.39 kg/m2 with BIA and 7.34 +/- 1.34 kg/m2 with DXA, (p < 0001). A formula developed using a multiple regression analysis, and taking into account muscle mass assessed by BIA, as well as sex and body mass index, explains 89% of the ALM/ht2 assessed by DXA. CONCLUSIONS: Although our results show that the measure of ALM/ht2 by BIA is reliable, the agreement between DXA and BIA is low. Indeed, BIA seems to overestimate ALM/ht2 compared to DXA and, consequently, it is important to use an adapted formula to obtain measurement of the appendicular lean mass by BIA close to that measured by DXA. [less ▲]

Detailed reference viewed: 72 (23 ULg)
Full Text
Peer Reviewed
See detailNIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways.
Rapino, Francesca ULg; Abhari, BA; Jung, M et al

in Cell Death & Disease (2015)

Detailed reference viewed: 5 (0 ULg)
Full Text
See detailEquipements remarquable: Passeport santé pour bananier
Massart, Sébastien ULg

in 15e Jour du Mois (Le) (2015), (242),

Detailed reference viewed: 15 (4 ULg)
Full Text
Peer Reviewed
See detailUnique recurrence patterns of cervical intraepithelial neoplasia following excision of the squamo-columnar junction.
Herfs, Michael ULg; SOMJA, Joan ULg; Howitt, Brooke E. et al

in International journal of cancer. Journal international du cancer (2015), 136

Recent studies have identified a putative cell of origin for cervical intraepithelial neoplasia (CIN) and cervical cancer at the squamo-columnar junction (SCJ) and suggest that these cells may not ... [more ▼]

Recent studies have identified a putative cell of origin for cervical intraepithelial neoplasia (CIN) and cervical cancer at the squamo-columnar junction (SCJ) and suggest that these cells may not regenerate following excision (LEEP). This study addressed the impact of SCJ excision on the temporal dynamics, histologic and viral (HPV) characteristics of recurrent CIN. One hundred thirty one consecutive patients treated by excision and attending follow-up visits were enrolled. We compared recurrent and initial CIN with attention to excision margins, timing of recurrence, CIN grade, HPV types, p16 immunophenotype, and SCJ immunophenotype. During the follow-up period (up to four years), sixteen (12.2%) recurrences were identified. Four (25%) were identified at the first follow-up visit, closely resembled the initial CIN 2/3 in grade and HPV type, and were typically SCJ marker positive [SCJ(+)], suggesting non-excised (residual) disease. Twelve (75%) manifested after the first postoperative visit and all were in the ectocervix or in mature metaplastic epithelium. All of the 12 delayed recurrences were classified as CIN 1 and were SCJ (-). Nine of 11 SCJ (-) recurrences (82%) followed regressed spontaneously. Taken together, these results show that new lesions developing from any HPV infection are delayed and occur within the ectocervix or metaplastic epithelium. This dramatically lower risk of CIN 2/3 following successful SCJ excision suggests that removal of the SCJ could be a critical variable in reducing the risk of subsequent CIN 2/3 and cervical cancer. (c) 2014 Wiley Periodicals, Inc. [less ▲]

Detailed reference viewed: 47 (6 ULg)
Full Text
Peer Reviewed
See detailWhat is important in being cured from depression? Discordance between physicians and patients (1)
Demyttenaere, Koen; Donneau, Anne-Françoise ULg; Albert, Adelin ULg et al

in Journal of Affective Disorders (2015), 174(2015), 390-396

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailMulti-period stochastic optimization problems in transportation management (Ph. D. Thesis Summary)
Pironet, Thierry ULg

in 4OR : Quarterly Journal of the Belgian, French and Italian Operations Research Societies (2015), 13(1), 113-114

Ph. D Thesis summary see other reference on ORBI

Detailed reference viewed: 16 (2 ULg)
Full Text
Peer Reviewed
See detailAssessing variability of literature based methane indicator traits in a large dairy cow population
Kandel, Purna Bhadra ULg; Gengler, Nicolas ULg; Soyeurt, Hélène ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2015), 19(1), 11-19

Description du sujet. La production laitière est reconnue comme une des sources majeures d’émissions de méthane (CH4). Le recours à un programme de sélection spécifique pourrait être une bonne méthode ... [more ▼]

Description du sujet. La production laitière est reconnue comme une des sources majeures d’émissions de méthane (CH4). Le recours à un programme de sélection spécifique pourrait être une bonne méthode pour optimiser les émissions de méthane par les vaches laitières. Le développement d’un tel programme nécessiterait un nombre important d’enregistrements relatifs aux émissions de méthane. Malheureusement, aucune méthode pratique et bon marché n’existe actuellement pour créer une telle base de données. Cependant, quatre indicateurs CH4 basés sur les quantités en acides gras dans la matière grasse laitière ont été recensés dans la littérature. Objectifs. L’objectif de cette étude est d’utiliser ces indicateurs de la littérature afin d’apprécier la variabilité des émissions de méthane éructées par les vaches laitières. Méthode. Ces indicateurs utilisent les quantités en acides gras obtenues par chromatographie en phase gazeuse. Comme ce type de données n’est pas disponible pour toute la population laitière, un échantillon de 602 analyses chromatographiques a été créé dans cette étude afin de développer une équation de calibrage permettant de prédire les quantités de méthane émises à partir du spectre moyen infrarouge (MIR) du lait qui est disponible pour toutes les vaches étudiées. Ensuite, l’équation de calibrage ainsi obtenue a été appliquée sur 604 028 données spectrales enregistrées entre 2007 et 2011 auprès de 70 872 vaches au cours de leurs trois premières lactations afin de prédire les quantités de méthane émises. Les paramètres génétiques de ces nouveaux indicateurs méthane prédits par MIR ont également été estimés en utilisant un modèle animal de type jour de test avec régressions aléatoires. Résultats. Ces quantités prédites par MIR variaient selon une gamme attendue s’étalant entre 350 ± 40 et 449 ± 65 g par jour. L’émission prédite moyenne de CH4 en g par jour augmentait au début de la lactation, atteignait sa plus haute concentration au pic de lactation et ensuite diminuait jusqu’à la fin de la lactation. Les héritabilités journalières moyennes variaient entre 0,29-0,35 ; 0,26-0,40 et 0,22-0,37 pour les différents indicateurs méthane étudiés au cours des trois premières lactations. Les plus grandes différences entre les valeurs d’élevage estimées pour des taureaux ayant des filles en production émettant le plus et le moins de méthane étaient de 24,18 ; 29,33 et 27,77 kg par lactation pour les trois premières lactations. Des corrélations faiblement négatives ont été observées entre les indicateurs CH4 et la quantité de lait. À l’inverse, des corrélations positives ont été estimées entre ces mêmes indicateurs et les taux en matières grasses et en protéines. Conclusions. Cette étude montre la possibilité de prédire des indicateurs méthane issus de la littérature et utilisant les concentrations en acides gras dans la matière grasse laitière à partir de la spectrométrie MIR. De plus, cette étude suggère également à partir des paramètres génétiques obtenus l’existence d’une variabilité phénotypique et génétique des quantités de méthane éructées par les vaches laitières Holstein. [less ▲]

Detailed reference viewed: 145 (59 ULg)
Full Text
Peer Reviewed
See detailData in support of metabolic reprogramming in transformed mouse cortical astrocytes: A proteomic study
Bentaib, Azeddine; De Tullio, Pascal ULg; Chneiweiss, Hervé et al

in Data in Brief (2015), 2(0), 1-5

2D-DIGE analysis coupled with mass spectrometry is a global, without a priori, comparative proteomic approach particularly suited to identify and quantify enzymes isoforms and structural proteins, thus ... [more ▼]

2D-DIGE analysis coupled with mass spectrometry is a global, without a priori, comparative proteomic approach particularly suited to identify and quantify enzymes isoforms and structural proteins, thus making it an efficient tool for the characterization of the changes in cell phenotypes that occur in physiological and pathological conditions. In this data article in support of the research article entitled “Metabolic reprogramming in transformed mouse cortical astrocytes: a proteomic study” [1] we illustrate the changes in protein profile that occur during the metabolic reprogramming undergone by cultured mouse astrocytes in a model of in-vitro cancerous transformation [2]. [less ▲]

Detailed reference viewed: 41 (4 ULg)
Full Text
Peer Reviewed
See detailAgriculture et changement climatique. Vers la définition d'un nouvel objectif para-agricole
Habran, Maxime ULg

in Revue de la Faculté de Droit de l'Université de Liège (2015), 2015-/1

Cette contribution illustre la façon dont le législateur européen tente d’adapter la PAC à la lutte contre le changement climatique. Dans le cadre de la nouvelle réforme mise en place en janvier 2014 et ... [more ▼]

Cette contribution illustre la façon dont le législateur européen tente d’adapter la PAC à la lutte contre le changement climatique. Dans le cadre de la nouvelle réforme mise en place en janvier 2014 et reportée début 2015, l’accent est mis sur les mesures prévues pour réaliser le nouvel objectif de la politique environnementale. [less ▲]

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailA generalized moving-boundary algorithm to predict the heat transfer rate of counterflow heat exchangers for any phase configuration
Bell, Ian; Quoilin, Sylvain ULg; Georges, Emeline ULg et al

in Applied Thermal Engineering (2015), 79

In this work, a novel and robust solution approach is presented that can be used to predict the steady-state thermal heat transfer rate for counterflow heat exchangers with any combination of single-phase ... [more ▼]

In this work, a novel and robust solution approach is presented that can be used to predict the steady-state thermal heat transfer rate for counterflow heat exchangers with any combination of single-phase and two-phase conditions within the heat exchanger. This methodology allows for multiple internal pinching points, as well as all permutations of subcooled liquid, two-phase and superheated vapor sections for the hot and cold fluids. A residual function based on the matching of the required and available thermal conductances in each section is derived, and Brent's method is then used to drive the residual to zero. Examples are presented for the application of this methodology to a water-heated n-Propane evaporator. The computational time required to execute the model for a simple case is on the order of one millisecond when the tabular interpolation methods of CoolProp are applied. Source code for the algorithm is provided in the Python programming language as an appendix. [less ▲]

Detailed reference viewed: 39 (3 ULg)
Full Text
Peer Reviewed
See detailBuilding on anticipation: dystopia as empowerment
Claisse, Frédéric ULg; Delvenne, Pierre ULg

in Current Sociology (2015), 63(2),

A dystopia can be defined as the depiction of a dark future building on the systematic amplification of current trends and features. It relates to a complex narrative posture that relies on the critical ... [more ▼]

A dystopia can be defined as the depiction of a dark future building on the systematic amplification of current trends and features. It relates to a complex narrative posture that relies on the critical observation of a threatening present that would lead to an apocalyptic future “if nothing was done.” Yet, however inescapable this future may be described, the very existence of such a narrative presupposes that the political community it tries to reach is actually able to do something to thwart it. Oddly enough, a successful dystopia aims at making itself obsolete: once the world it depicts is identified as a possible (or even unavoidable) future, it seems to empower its readers again, restoring what Musil called a ‘sense of possibilities’ that eventually make alternative pathways thinkable. In our contribution, we propose to broaden the range of commonly accepted dystopists (usually fiction writers and novelists like e.g. George Orwell’s 1984) to sociologists like Ulrich Beck. Building on his Risk Society (1986), Beck’s strong diagnosis about the breakdown of First Modernity and the coming of Second Modernity contains a noticeable prophetic and evangelical overtone that aims at “reinventing politics.” We defend the notion that the dystopian posture can be used to characterize both fiction and nonfiction writers such as Orwell and Beck: a common ability, based on the same set of inextricably cognitive and normative patterns, to anticipate the future and eventually empower political communities to engage in further action. [less ▲]

Detailed reference viewed: 177 (20 ULg)
Full Text
Peer Reviewed
See detailCharacterization of building materials from the aqueduct of Antioch-on-the-Orontes (Turkey)
Benjelloun, Yacine; de Sigoyer, Julia; Carlut, Julia et al

in Comptes Rendus Geoscience (2015)

The Roman aqueduct of Antioch-on-the-Orontes (Turkey), a city located near the junction between the active Dead Sea fault and the East Anatolian fault, has been damaged several times due to historical ... [more ▼]

The Roman aqueduct of Antioch-on-the-Orontes (Turkey), a city located near the junction between the active Dead Sea fault and the East Anatolian fault, has been damaged several times due to historical earthquakes, as mentioned in ancient texts. The traces of repairs are studied in order to identify their potential seismic origin. The deformations of the structure were characterised thanks to a LIDAR scan. Several bricks were sampled on different parts of the city’s aqueducts, on the original structure and on repaired parts. The bricks were characterized through a petrological approach. 14C and archaeomagnetism were tested on the bricks in order to constrain the age of their production. The synthesis of all the data showed a local origin for the bricks, and led to the identification of several manufacturing techniques and several types of production, thus, confirming the potentiality of this approach to date and characterise post-seismic repairs. [less ▲]

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailA connection between the instability strips of ZZ Ceti and V777 Her white dwarfs
Van Grootel, Valérie ULg; Fontaine, Gilles; Brassard, Pierre et al

in Astronomy and Astrophysics (2015), 575

Aims. We aim to determine the theoretical instability strips of white dwarfs with diverse H and He content in their atmospheres, from a solar composition to a H-depleted atmosphere. Pulsators with mixed H ... [more ▼]

Aims. We aim to determine the theoretical instability strips of white dwarfs with diverse H and He content in their atmospheres, from a solar composition to a H-depleted atmosphere. Pulsators with mixed H-He atmospheres are indeed known to exist, and these are the white dwarfs in cataclysmic accreting systems of the GW Lib type. We thus also aim to determine the range of periods of excited pulsation modes, and to qualitatively compare these to the observed periods in GW Lib white dwarf pulsators. Methods. In the first full nonadiabatic stability analysis of pulsators of this kind, we applied a time-dependent convection treatment and an energy leakage argument to compute, for cooling models of white dwarfs with various masses and envelope compositions, the location of the blue and the red edges, as well as the properties of pulsation modes. Results. We find that our derived instability strips form a true continuum in the log g-Teff plane and that their individual location depends uniquely on the assumed atmospheric composition, from the solar composition models at low effective temperatures to the H-depleted models at much higher temperatures. Taking into account our previous results from the ZZ Ceti (pure H atmosphere) and V777 Her (pure He atmosphere) white dwarf pulsators, this implies that all of these instability domains are connected via the same fundamental driving mechanism. Applying our results to the case of white dwarf pulsators of the GW Lib type, we find that our theoretical instability strips can qualitatively account for all of the known cases. The computed range of periods of excited modes also compares qualitatively very well to the observed ones. Conclusions. The GW Lib pulsators are very similar in nature to ZZ Ceti and V777 Her white dwarfs. It is the diverse chemical compositions in their atmosphere and envelope that defines their specific pulsation properties. Beyond GW Lib pulsators, white dwarfs can sometimes exhibit mixed H-He atmospheres, such as in the recently found proto-He white dwarf pulsators. Our results open the way towards quantitative asteroseismology of these various kinds of white dwarfs. [less ▲]

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailComplexity markers in morphosyntactic productions in French-speaking children with specific language impairment (SLI)
Prigent, Gaïd ULg; Parisse, Christophe; Leclercq, Anne-Lise ULg et al

in Clinical Linguistics & Phonetics (2015)

The usage-based theory considers that the morphosyntactic productions of children with SLI are particularly dependent on input frequency. When producing complex syntax, the language of these children is ... [more ▼]

The usage-based theory considers that the morphosyntactic productions of children with SLI are particularly dependent on input frequency. When producing complex syntax, the language of these children is, therefore, predicted to have a lower variability and to contain fewer infrequent morphosyntactic markers than that of younger children matched on morphosyntactic abilities. Using a spontaneous language task, the current study compared the complexity of the morphological and structural productions of 20 children with SLI and 20 language-matched peers (matched on both morphosyntactic comprehension and mean length of utterance). As expected, results showed that although basic structures were produced in the same way in both groups, several complex forms (i.e. tenses such as Imperfect, Future or Conditional and Conjunctions) were less frequent in the productions of children with SLI. Finally, we attempted to highlight complex linguistic forms that could be good clinical markers for these children. [less ▲]

Detailed reference viewed: 63 (15 ULg)
Full Text
Peer Reviewed
See detailImpact de l’hygiène bucco-dentaire sur le sport. Revue de la littérature
Kipgen, Laurence; Kaux, Jean-François ULg; Rompen, Eric ULg et al

in Journal de Traumatologie du Sport (2015), 32(1), 41-45

Teeth are the object of multiple attentions and care but unfortunately, it is not the same case of the periodonte, their point of anchoring and essential support. What could be more commonplace than a ... [more ▼]

Teeth are the object of multiple attentions and care but unfortunately, it is not the same case of the periodonte, their point of anchoring and essential support. What could be more commonplace than a bleeding arising during the daily brushing? Being not painful, it activates very often no concern and no request of consultation. It is nevertheless about one of the most obvious clinical signs of the periodontal diseases which affect, to varying degrees, practically 90 % of the population in France in all groups of ages and is responsible of the loss from 30 to 40 % of the teeth. For several decades, the scientific world admits a relation between the periodontal disease and certain systematic diseases, as the endocarditis, the atherosclerosis, the diabetes… And what about tendinopathies? Their appearance is often spontaneous without specific medical origin and their cure turns out long and painful. This review has for objective to highlight the relations between the oral hygiene and sportsmen. [less ▲]

Detailed reference viewed: 68 (14 ULg)
Full Text
Peer Reviewed
See detaileffects of cholecaciferol supplementation and optimized calcium intakes on vitamin D status, muscle strength and bone health: a one-year pilot randomized controlled trial in adults with severe burns
ROUSSEAU, Anne-Françoise ULg; FOIDART-DESSALLE, Marguerite ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (2015), 41(2), 317-325

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess ... [more ▼]

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess effects of a cholecalciferol (VD3) supplementation and an optimized calcium (Ca) regimen on vitamin D (VD) status, bone and muscle health during sequelar stage of burn injury. Design: Monocentric randomized controlled trial. Methods: Fifteen adults with thermal burns dating from 2 to 5 years were randomized into two groups. For 12 months, they either received a quarterly IM injection of 200,000 IU VD3 and daily oral Ca (Group D) or placebo (Group P). VD status and bone remodeling markers were assessed every 3 months. Knee muscle strength and bone mineral density were, respectively, assessed using isokinetic dynamometry and dual X-ray absorptiometry at initiation (M0) and completion (M12) of the protocol. Results: Of all the patients, 66% presented with VD deficiency and 53% (with 3 men <40 y) were considered osteopenic at inclusion. After one year, calcidiol levels significantly increased in Group D to reach 40 (37–61) ng/ml. No significant change in bone health was observed in both groups while Group D significantly improved quadriceps strength when tested at high velocity. Conclusions: This VD3 supplementation was safe and efficient to correct hypovitaminosis D in burn adults. When combined with optimized Ca intakes, it demonstrated positive effects on muscle health but not on bone health. A high prevalence of hypovitaminosis D and osteopenia in these patients, as well as their wide range of muscle performances, seem to be worrying when considering rehabilitation and quality of life. [less ▲]

Detailed reference viewed: 21 (6 ULg)
Full Text
See detailL'accoutumance à l'eau: un préalable au savoir-nager.
Mornard, Manhattan ULg; Delvaux, Anne ULg; Cloes, Marc ULg et al

in Éducation Physique et Sport (2015), (364), 16-20

Synthèse de la méthodologie et des travaux scientifiques réalisés au cours de ces dernières années par le cereki dans le domaine de l'accoutumance à l'eau.

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailMagnetosphere-ionosphere mapping at Jupiter: Quantifying the effects of using different internal field models
Vogt, Marissa; Bunce, Emma; Kivelson, Margaret et al

in Journal of Geophysical Research. Space Physics (2015), 120

The lack of global field models accurate beyond the inner magnetosphere (<30 RJ) makes it difficult to relate Jupiter's polar auroral features to magnetospheric source regions. We recently developed a ... [more ▼]

The lack of global field models accurate beyond the inner magnetosphere (<30 RJ) makes it difficult to relate Jupiter's polar auroral features to magnetospheric source regions. We recently developed a model that maps Jupiter's equatorial magnetosphere to the ionosphere using a flux equivalence calculation that requires equal flux at the equatorial and ionospheric ends of flux tubes. This approach is more accurate than tracing field lines in a global field model but only if it is based on an accurate model of Jupiter's internal field. At present there are three widely used internal field models—Voyager Io Pioneer 4 (VIP4), the Grodent Anomaly Model (GAM), and VIP Anomaly Longitude (VIPAL). The purpose of this study is to quantify how the choice of an internal field model affects the mapping of various auroral features using the flux equivalence calculation. We find that different internal field models can shift the ionospheric mapping of points in the equatorial plane by several degrees and shift the magnetospheric mapping to the equator by ~30 RJ radially and by less than 1 h in local time. These shifts are consistent with differences in how well each model maps the Ganymede footprint, underscoring the need for more accurate Jovian internal field models. We discuss differences in the mapping of specific auroral features and the size and location of the open/closed field line boundary. Understanding these differences is important for the continued analysis of Hubble Space Telescope images and in planning for Juno's arrival at Jupiter in 2016. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailTensor Representation of Spin States
Giraud, Olivier; Braun, Daniel; Baguette, Dorian ULg et al

in Physical Review Letters (2015), 114

We propose a generalization of the Bloch sphere representation for arbitrary spin states. It provides a compact and elegant representation of spin density matrices in terms of tensors that share the most ... [more ▼]

We propose a generalization of the Bloch sphere representation for arbitrary spin states. It provides a compact and elegant representation of spin density matrices in terms of tensors that share the most important properties of Bloch vectors. Our representation, based on covariant matrices introduced by Weinberg in the context of quantum field theory, allows for a simple parametrization of coherent spin states, and a straightforward transformation of density matrices under local unitary and partial tracing operations. It enables us to provide a criterion for anticoherence, relevant in a broader context such as quantum polarization of light. [less ▲]

Detailed reference viewed: 32 (15 ULg)
Full Text
Peer Reviewed
See detailTensor Representation of Spin States
Giraud, Olivier; Braun, Daniel; Baguette, Dorian ULg et al

in Physical Review Letters (2015), 114

We propose a generalization of the Bloch sphere representation for arbitrary spin states. It provides a compact and elegant representation of spin density matrices in terms of tensors that share the most ... [more ▼]

We propose a generalization of the Bloch sphere representation for arbitrary spin states. It provides a compact and elegant representation of spin density matrices in terms of tensors that share the most important properties of Bloch vectors. Our representation, based on covariant matrices introduced by Weinberg in the context of quantum field theory, allows for a simple parametrization of coherent spin states, and a straightforward transformation of density matrices under local unitary and partial tracing operations. It enables us to provide a criterion for anticoherence, relevant in a broader context such as quantum polarization of light. [less ▲]

Detailed reference viewed: 32 (15 ULg)
Full Text
Peer Reviewed
See detailProtection of Antarctic microbial communities–‘out of sight, out of mind’
Hughes, Kevin; Cowan, Don; Wilmotte, Annick ULg

in Frontiers in Microbiology (2015), 6(151), 1-6

RecentadvancesinmolecularbiologytechniqueshaveshownthepresenceofdiversemicrobialcommunitiesandendemicspeciesinAntarctica.Endemicmicrobesmaybeapotentialsourceofnovelbiotechnologicallyimportantcompounds ... [more ▼]

RecentadvancesinmolecularbiologytechniqueshaveshownthepresenceofdiversemicrobialcommunitiesandendemicspeciesinAntarctica.Endemicmicrobesmaybeapotentialsourceofnovelbiotechnologicallyimportantcompounds,including,forexample,newantibiotics.Thus,thescientificandbiotechnologicalvalueofAntarcticterrestrialmicrobialhabitatscanbecompromisedbyhumanvisitationtoagreaterextentthanpreviouslyrealized.Theever-increasinghumanfootprintinAntarcticamakesconsiderationofthistopicmorepressing,asthenumberoflocationsknowntobepristinehabitats,whereincreasinglysophisticatedcutting-edgeresearchtechniquesmaybeusedtotheirfullpotential,declines.ExaminationoftheProtectedAreassystemoftheAntarcticTreatyshowsthatmicrobialhabitatsaregenerallypoorlyprotected.NoothercontinentonEarthisdominatedtothesamedegreebymicrobialspecies,andrealopportunitiesexisttodevelopnewwaysofconceptualizingandimplementingconservationofmicrobialbiogeographyonacontinentalscale.Herewehighlightpotentialthreatsbothtotheconservationofterrestrialmicrobialecosystems,andtofuturescientificresearchrequiringtheirstudy. [less ▲]

Detailed reference viewed: 19 (2 ULg)
Full Text
Peer Reviewed
See detailRetirement age and the age of onset of Alzheimer’s disease: Results from the ICTUS study
Grotz, Catherine ULg; Letenneur, Luc; Bonsang, Eric ULg et al

in PLoS ONE (2015)

Detailed reference viewed: 50 (19 ULg)
Full Text
Peer Reviewed
See detailPoly(vinyl ester 1,2,3-triazolium)s: a new member of the poly(ionic liquid)s family
Obadia, M. M.; Colliat-Dangus, G.; Debuigne, Antoine ULg et al

in Chemical Communications (2015), 51(16), 3332-3335

A vinyl ester monomer carrying a pendant 1,2,3-triazole group is synthesized in two steps and polymerized by cobalt-mediated radical polymerization. Subsequent alkylation with N-methyl bis ... [more ▼]

A vinyl ester monomer carrying a pendant 1,2,3-triazole group is synthesized in two steps and polymerized by cobalt-mediated radical polymerization. Subsequent alkylation with N-methyl bis[(trifluoromethyl)sulfonyl]imide affords the corresponding poly(vinyl ester 1,2,3-triazolium). This unprecedented example of poly(vinyl ester ionic liquid) exhibits an ionic conductivity of 9.2 × 10(-7) S cm(-1) at 30 °C [less ▲]

Detailed reference viewed: 29 (4 ULg)
Full Text
Peer Reviewed
See detailGranular transport in driven granular gas
Noirhomme, Martial ULg; Opsomer, Eric ULg; Ludewig, François ULg et al

in European Physical Journal E -- Soft Matter (2015), 38

We numerically and theoretically investigate the behavior of a granular gas driven by asymmetric plates. The injection of energy in the dissipative system differs from one side to the opposite one. We ... [more ▼]

We numerically and theoretically investigate the behavior of a granular gas driven by asymmetric plates. The injection of energy in the dissipative system differs from one side to the opposite one. We prove that the dynamical clustering which is expected for such a system is affected by the asymmetry. As a consequence, the cluster position can be fully controlled. This property could lead to various applications in the handling of granular materials in low-gravity environment. Moreover, the dynamical cluster is characterized by natural oscillations which are also captured by a model. These oscillations are mainly related to the cluster size, thus providing an original way to probe the clustering behavior. [less ▲]

Detailed reference viewed: 16 (5 ULg)
Full Text
Peer Reviewed
See detailLead concentrations and isotope ratios in speleothems as proxies for atmospheric metal pollution since the Industrial Revolution
Allan, Mohammed ULg; Fagel, Nathalie ULg; Van Rampelbergh, maite et al

in Chemical Geology (2015)

Lead concentrations and isotope ratios from two speleothems from the Han-sur-Lesse cave in southern Belgium were measured in order to study the ability of speleothems to act as archives of atmospheric ... [more ▼]

Lead concentrations and isotope ratios from two speleothems from the Han-sur-Lesse cave in southern Belgium were measured in order to study the ability of speleothems to act as archives of atmospheric pollution. To address this aim we analyzed trace elemental Al and Pb compositions by LA-ICP-MS and ICP-MS as well as Pb isotopes by MC-ICP-MS. The results help to identify three intervals characterized by particularly high enrichment of Pb: from 1880 to 1905 AD, from 1945 to 1965 AD, and from 1975 to 1990 AD. The speleothem record shows similar changes as the known historical atmospheric pollution level in Belgium. Lead isotope ratios discriminate between Pb sources and confirm that coal and gasoline combustion, combined with regional metallurgical activities, were the predominant Pb pollution sources in the stalagmites during the last 250 years. This study opens possibilities to determine anthropogenic versus natural metal sources in well-dated speleothem archives. [less ▲]

Detailed reference viewed: 82 (57 ULg)
Full Text
Peer Reviewed
See detailResonant and antiresonant bouncing droplets
Hubert, Maxime ULg; Robert, Damien; Caps, Hervé ULg et al

in Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2015), 91

When placed onto a vibrating liquid bath, a droplet may adopt a permanent bouncing behavior, depending on both the forcing frequency and the forcing amplitude. The relationship between the droplet ... [more ▼]

When placed onto a vibrating liquid bath, a droplet may adopt a permanent bouncing behavior, depending on both the forcing frequency and the forcing amplitude. The relationship between the droplet deformations and the bouncing mechanism is studied experimentally and theoretically through an asymmetric and dissipative bouncing spring model. Antiresonance phenomena are evidenced. Experiments and theoretical predictions show that both resonance at specific frequencies and antiresonance at Rayleigh frequencies play crucial roles in the bouncing mechanism. In particular, we show that they could be exploited for bouncing droplet size selection. [less ▲]

Detailed reference viewed: 24 (6 ULg)
Full Text
Peer Reviewed
See detailTwo-Photon Luminescence of Gold Nanorods Mediated by Higher Order Plasmon Modes
Verellen, Niels; Denkova, Denitza; De Clercq, Ben et al

in ACS Photonics (2015), 2

Metallic nanorod antennas can be considered as an analogue to classical half-wave dipole antennas, constituting an important tool for manipulating linear and nonlinear lightmatter interactions in ... [more ▼]

Metallic nanorod antennas can be considered as an analogue to classical half-wave dipole antennas, constituting an important tool for manipulating linear and nonlinear lightmatter interactions in nanoscale volumes. Using two-photon luminescence (TPL) scanning laser microscopy, we investigate such optical antennas beyond their fundamental dipole mode. The antenna mode dispersion is extracted from the nonlinear TPL measurement and reveals a TPL process that is dominated by plasmon-induced enhancement of the two photon absorption in the metal. Additionally, a clear signature of the mode parity is observed in the TPL images. TPL maxima are observed outside the antenna boundaries for even parity modes, whereas they are located inside for odd modes. It is concluded that for even modes the two-photon luminescence emission is strongly mediated by retardation of the excitation field, a consequence of their zero net-dipole moment. This selective excitation of different mode parities is highly relevant for nanoscale enhanced nonlinear optics, as well as plasmonic nanosensor applications and tuning of radiative properties of quantum emitters. [less ▲]

Detailed reference viewed: 39 (7 ULg)
Full Text
Peer Reviewed
See detailTransient internally driven aurora at Jupiter discovered by Hisaki and the Hubble Space Telescope
Kimura, Tomoki; Badman, Sarah; Tao, Chihiro et al

in Geophysical Research Letters (2015), 42

Jupiter’s auroral emissions reveal energy transport and dissipation through the planet’s giant magnetosphere. While the main auroral emission is internally driven by planetary rotation in the steady state ... [more ▼]

Jupiter’s auroral emissions reveal energy transport and dissipation through the planet’s giant magnetosphere. While the main auroral emission is internally driven by planetary rotation in the steady state, transient brightenings are generally thought to be triggered by compression by the external solar wind. Here we present evidence provided by the new Hisaki spacecraft and the Hubble Space Telescope that shows that such brightening of Jupiter’s aurora can in fact be internally driven. The brightening has an excess power up to ~550 GW. Intense emission appears from the polar cap region down to latitudes around Io’s footprint aurora, suggesting a rapid energy input into the polar region by the internal plasma circulation process. [less ▲]

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailRational Development of an Attenuated Recombinant Cyprinid Herpesvirus 3 Vaccine Using Prokaryotic Mutagenesis and In Vivo Bioluminescent Imaging
Boutier, Maxime ULg; Ronsmans, Maygane ULg; Ouyang, Ping et al

in PLoS Pathogens (2015), 11(2), 1004690

Cyprinid herpesvirus 3 (CyHV 3) is causing severe economic losses worldwide in common and koi carp industries, and a safe and efficacious attenuated vaccine compatible with mass vaccination is needed. We ... [more ▼]

Cyprinid herpesvirus 3 (CyHV 3) is causing severe economic losses worldwide in common and koi carp industries, and a safe and efficacious attenuated vaccine compatible with mass vaccination is needed. We produced single deleted recombinants using prokaryotic mutagenesis. When producing a recombinant lacking open reading frame 134 (ORF134), we unexpectedly obtained a clone with additional deletion of ORF56 and ORF57. This triple deleted recombinant replicated efficiently in vitro and expressed an in vivo safety/efficacy profile compatible with use as an attenuated vaccine. To determine the role of the double ORF56-57 deletion in the phenotype and to improve further the quality of the vaccine candidate, a series of deleted recombinants was produced and tested in vivo. These experiments led to the selection of a double deleted recombinant lacking ORF56 and ORF57 as a vaccine candidate. The safety and efficacy of this strain were studied using an in vivo bioluminescent imaging system (IVIS), qPCR, and histopathological examination, which demonstrated that it enters fish via skin infection similar to the wild type strain. However, compared to the parental wild type strain, the vaccine candidate replicated at lower levels and spread less efficiently to secondary sites of infection. Transmission experiments allowing water contamination with or without additional physical contact between fish demonstrated that the vaccine candidate has a reduced ability to spread from vaccinated fish to naïve sentinel cohabitants. Finally, IVIS analyses demonstrated that the vaccine candidate induces a protective mucosal immune response at the portal of entry. Thus, the present study is the first to report the rational development of a recombinant attenuated vaccine against CyHV 3 for mass vaccination of carp. We also demonstrated the relevance of the CyHV 3 carp model for studying alloherpesvirus transmission and mucosal immunity in teleost skin. [less ▲]

Detailed reference viewed: 20 (5 ULg)
Full Text
Peer Reviewed
See detailDynamic Input Conductances Shape Neuronal Spiking
Drion, Guillaume ULg; Franci, Alessio ULg; Dethier, Julie ULg et al

in eNeuro (2015)

Assessing the role of biophysical parameter variations in neuronal activity is critical to the understanding of modulation, robustness and homeostasis of neuronal signaling. The paper proposes that this ... [more ▼]

Assessing the role of biophysical parameter variations in neuronal activity is critical to the understanding of modulation, robustness and homeostasis of neuronal signaling. The paper proposes that this question can be addressed through the analysis of dynamic input conductances. Those voltage-dependent curves aggregate the concomitant activity of all ion channels in distinct timescales. They are shown to shape the current-voltage dynamical relationships that determine neuronal spiking. We propose an experimental protocol to measure dynamic input conductances in neurons. In addition, we provide a computational method to extract dynamic input conductances from arbitrary conductance-based models and to analyze their sensitivity to arbitrary parameters. We illustrate the relevance of the proposed approach for modulation, compensation and robustness studies in a published neuron model based on data of the stomatogastric ganglion of the crab Cancer borealis. [less ▲]

Detailed reference viewed: 19 (3 ULg)
Full Text
Peer Reviewed
See detailDUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis
Musumeci, Lucia ULg; Kuijpers, Marijke; Gilio, Karen et al

in Circulation (2015), 131(7), 656-68

Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet ... [more ▼]

Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet activation is of importance for the development of improved therapies. Recently, protein tyrosine phosphatases (PTPs) have emerged as critical regulators of platelet function. Methods and Results This is the first report implicating the dual-specificity phosphatase 3 (DUSP3) in platelet signaling and thrombosis. This phosphatase is highly expressed in human and mouse platelets. Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion mediated through the collagen receptor glycoprotein VI (GPVI) and the C-type lectin-like receptor 2 (CLEC-2). DUSP3-deficient mice were more resistant to collagen- and epinephrine-induced thromboembolism, compared to wild-type mice, and showed severely impaired thrombus formation upon ferric chloride-induced carotid artery injury. Intriguingly, bleeding times were not altered in DUSP3-deficient mice. At the molecular level, DUSP3 deficiency impaired Syk tyrosine phosphorylation, subsequently reducing phosphorylation of PLCγ2 and calcium fluxes. To investigate DUSP3 function in human platelets, a novel small-molecule inhibitor of DUSP3 was developed. This compound specifically inhibited collagen and CLEC-2-induced human platelet aggregation, thereby phenocopying the effect of DUSP3 deficiency in murine cells. Conclusions DUSP3 plays a selective and essential role in collagen- and CLEC-2-mediated platelet activation and thrombus formation in vivo. Inhibition of DUSP3 may prove therapeutic for arterial thrombosis. This is the first time a PTP, implicated in platelet signaling, has been targeted with a small-molecule drug. [less ▲]

Detailed reference viewed: 94 (36 ULg)
Full Text
Peer Reviewed
See detailA flux extraction device to measure the magnetic moment of large samples; application to bulk superconductors
Egan, Raphael ULg; Philippe, Matthieu ULg; Wera, Laurent ULg et al

in Review of Scientific Instruments (2015), 86(2), 025107

We report the design and construction of a flux extraction device to measure the DC magnetic moment of large samples (i.e., several cm3) at cryogenic temperature. The signal is constructed by integrating ... [more ▼]

We report the design and construction of a flux extraction device to measure the DC magnetic moment of large samples (i.e., several cm3) at cryogenic temperature. The signal is constructed by integrating the electromotive force generated by two coils wound in series-opposition that move around the sample. We show that an octupole expansion of the magnetic vector potential can be used conveniently to treat near-field effects for this geometrical configuration. The resulting expansion is tested for the case of a large, permanently magnetized, type-II superconducting sample. The dimensions of the sensing coils are determined in such a way that the measurement is influenced by the dipole magnetic moment of the sample and not by moments of higher order, within user-determined upper bounds. The device, which is able to measure magnetic moments in excess of 1 Am2 (1000 emu), is validated by (i) a direct calibration experiment using a small coil driven by a known current and (ii) by comparison with the results of numerical calculations obtained previously using a flux measurement technique. The sensitivity of the device is demonstrated by the measurement of flux-creep relaxation of the magnetization in a large bulk superconductor sample at liquid nitrogen temperature (77 K). [less ▲]

Detailed reference viewed: 45 (24 ULg)
Full Text
Peer Reviewed
See detailTen years of Martian nitric oxide nightglow observations
Stiepen, Arnaud ULg; Gérard, Jean-Claude ULg; Gagné, Marie-Eve et al

in Geophysical Research Letters (2015)

Detailed reference viewed: 20 (4 ULg)
Full Text
Peer Reviewed
See detailDark anti atoms can explain DAMA
Wallemacq, Quentin ULg; Cudell, Jean-René ULg

in Journal of Cosmology and Astroparticle Physics [= JCAP] (2015)

We show that the existence of a sub-dominant form of dark matter, made of dark 'antiatoms' of a mass of 1 TeV and a size of 30 fm, can explain the results of direct detection experiments, with a positive ... [more ▼]

We show that the existence of a sub-dominant form of dark matter, made of dark 'antiatoms' of a mass of 1 TeV and a size of 30 fm, can explain the results of direct detection experiments, with a positive signal in DAMA/NaI and DAMA/LIBRA and no signal in other experiments. The signal comes from the binding of the dark anti-atoms to thallium, a dopant in DAMA, and is not present for the constituent atoms of other experiments. The dark anti-atoms are made of two particles oppositely charged under a dark U(1) symmetry and can bind to terrestrial atoms because of a kinetic mixing between the photon and the massless dark photon, such that the dark particles acquire an electric milli-charge of ± 5.10(−)(4)e. This millicharge enables them to bind to high-Z atoms via radiative capture, after they thermalize in terrestrial matter through elastic collisions. [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailHighly efficient, long life, reusable and robust photosynthetic hybrid core-shell beads for the sustainable production of high value compounds
Desmet, Jonathan; Meunier, Christophe; Danloy, Emeric et al

in Journal of Colloid & Interface Science (2015), 448

An efficient one-step process to synthesize highly porous (Ca-alginate–SiO2–polycation) shell: (Na-alginate– SiO2) core hybrid beads for cell encapsulation, yielding a reusable long-life ... [more ▼]

An efficient one-step process to synthesize highly porous (Ca-alginate–SiO2–polycation) shell: (Na-alginate– SiO2) core hybrid beads for cell encapsulation, yielding a reusable long-life photosynthetically active material for a sustainable manufacture of high-value metabolites is presented. Bead formation is based on crosslinking of an alginate biopolymer and mineralisation of silicic acid in combination with a coacervation process between a polycation and the silica sol, forming a semi-permeable external membrane. The excellent mechanical strength and durability of the monodispersed beads and the control of their porosity and textural properties is achieved by tailoring the silica and alginate loading, polycation concentration and incubation time during coacervation. This process has led to the formation of a remarkably robust hybrid material that confers exceptional protection to live cells against sheer stresses and contamination in a diverse range of applications. Dunaliella tertiolecta encapsulated within this hybrid core–shell system display high photosynthetic activity over a long duration (>1 year). This sustainable biotechnology could find use in high value chemical harvests and biofuel cells to photosynthetic solar cells (energy transformation, electricity production, water splitting technologies). Furthermore the material can be engineered into various forms from spheres to variable thickness films, broadening its potential applications. 2015 Elsevier Inc. All rights reserved. [less ▲]

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailSynthesis and anticancer activities of a novel class of mono- and di-metallic Pt(II)(salicylaldiminato)- (DMSO or Picolino)Cl complexes
Faiz-Ur Rahman; Ali, Amjad ULg; Rong Guo et al

in Dalton Transactions (2015)

A series of novel Pt(II) complexes [cis- and trans-Pt(II)(salicylaldimine)(DMSO)Cl (C-1), trans-Pt(II)(salicylaldimine)( 4-picoline)Cl (C-2), Pt(II)(salicylaldimine)Cl (C-3), trans- and cis/trans-Pt2(II ... [more ▼]

A series of novel Pt(II) complexes [cis- and trans-Pt(II)(salicylaldimine)(DMSO)Cl (C-1), trans-Pt(II)(salicylaldimine)( 4-picoline)Cl (C-2), Pt(II)(salicylaldimine)Cl (C-3), trans- and cis/trans-Pt2(II)(salicylaldimine) (DMSO)2Cl2 (C-4), trans-Pt2(II)(salicylaldimine)(4-picoline)2Cl2 (C-5) was synthesized and characterized. The structures of C-1-cis, C-1-trans and C-3 were determined using a single crystal X-ray analysis. This class of Pt(II) complexes has been studied for their in vitro cytotoxicity in multiple human cancer cell lines, including breast (MCF-7), liver (HepG2), lung (A549), colon (HCT116) and cervical (Hela) cancers. C-1- trans, C-2 and C-4-trans showed significant cytotoxicity to these cancer cells comparable to cisplatin. A time- and dose-dependent MTT assay revealed that these complexes can suppress cell viability and cell proliferation. Mechanistically these complexes induced pro-apoptotic gene expression such as BAX, PUMA and NOXA and thereby enhanced apoptosis. Moreover, PARP cleavage in a dose-dependent manner indicated their cytotoxic effect against cancer cells. Apoptosis of cancer cells occurred through apoptotic pathways as explained by the cytometry analysis. The DNA unwinding properties of these active Pt(II) complexes were studied by gel electrophoresis using pBR322 plasmid DNA as a target. Changes in the morphology of cancer cells were also observed upon the addition of C-1-trans, C-2 and C-4-trans. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailMethionine-derived Schiff base as selective fluorescent “turn-on”chemosensor for Zn2+in aqueous medium and its application in livingcells imaging
Faiz-Ur-Rahman; Ali, Amjad ULg; Rong Guo et al

in Sensors and Actuators B: Chemical (2015)

tWe describe the quantitative synthesis of a Schiff base derived from methionine and salicylaldehyde(SMSB) which displayed turn-on selective fluorescent chemo-sensing properties for Zn2+in bufferedCH3CN ... [more ▼]

tWe describe the quantitative synthesis of a Schiff base derived from methionine and salicylaldehyde(SMSB) which displayed turn-on selective fluorescent chemo-sensing properties for Zn2+in bufferedCH3CN/H2O (1:1) solution. In physiological pH (7.2 buffered) SMSB exhibited high selectivity and sen-sitivity toward Zn2+over the other selected metal ions. Upon the addition of Zn2+33 folds of emissionenhancement was observed in SMSB and limit of detection (CL) for Zn2+was found to be 5.0 × 10−7M. Thisbinding phenomenon was studied by1H NMR and HR-MS analysis. Mass spectrometry analysis revealedthat SMSB interacts with Zn2+and form a 1:1 complex, also confirmed by Job’s plot. This probe wascompletely retrieved by adding EDTANa2solution, exhibited a fluorescent quenching effect by removingZn2+from the sensor. SMSB was observed to have a good tolerance for fluorescence detection of Zn2+in pH range 6–10. Furthermore it is successfully investigated for living cells imaging using MCF-7 cells.Combine experimental results indicated SMSB to be a useful and powerful chemosensing probe for Zn2+in water as well as in living cells. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailIn situ investigation of scCO2 assisted impregnation of drug into polymer by high pressure FTIR micro-spectroscopy
Champeau, Mathilde ULg; Thomassin, Jean-Michel ULg; Jérôme, Christine ULg et al

in Analyst (2015), 140(3), 869-879

An original experimental set-up combining a FTIR microscope with a high pressure cell has been built in order to analyze in-situ the impregnation of solute into microscopic polymer samples, such as fibers ... [more ▼]

An original experimental set-up combining a FTIR microscope with a high pressure cell has been built in order to analyze in-situ the impregnation of solute into microscopic polymer samples, such as fibers or films, subjected to supercritical CO2. Thanks to this experimental set-up, key factors governing the impregnation process can be simultaneously followed such as the swelling of the polymeric matrix, the CO2 sorption, the kinetic of impregnation and the drug loading into the matrix. Moreover, the solute/polymer interactions and the speciation of the solute can be analyzed. We have monitored in situ the impregnation of aspirin and ketoprofen into PEO (Polyethylene Oxide) platelets at T=40°C and P=5; 10 and 15 MPa. The kinetic of impregnation of aspirin was quicker than the one of ketoprofen and the final drug loading was also higher in case of aspirin. Whereas the CO2 sorption and the PEO swelling remain constant when PEO is just subjected to CO2 under isobaric conditions, we noticed that both parameters can increase while the drug impregnates PEO. Coupling these results with DSC measurements, we underlined the plasticizing effect of the drug that also leads to decrease the crystallinity of PEO in situ thus favoring the sorption of CO2 molecules into the matrix and the swelling of the matrix. The plasticizing effect increases with the drug loading. Finally, the speciation of drug was investigated considering the shift of the carboxyl bands of the drugs. Both drugs were found to be mainly homogeneously dispersed into PEO. [less ▲]

Detailed reference viewed: 45 (9 ULg)
Full Text
Peer Reviewed
See detailSingle Wavelength Coarse Phasing In Segmented Telescopes
Simar, Juan Felipe ULg

in Applied Optics (2015), 54

Space observations of fainter and more distant astronomical objects constantly require telescope primary mirrors with a larger size. The diameter of monolithic primary mirrors is limited to 10 m because ... [more ▼]

Space observations of fainter and more distant astronomical objects constantly require telescope primary mirrors with a larger size. The diameter of monolithic primary mirrors is limited to 10 m because of manufacturing limitations. For space telescopes, the primary mirrors are limited to less than 5 m due to fairing capacity. Segmented primary mirrors thus constitute an alternative solution to deal with the steadily increase of the primary mirror size. The optical path di erence between the individual segments must be close to zero (few nm) in order to be di raction limited. We propose in this paper a new inter-segment piston sensor based on coherence measurement of a star image. This sensor is intended to be used in the co-phasing system of future segmented mirrors. [less ▲]

Detailed reference viewed: 64 (37 ULg)
Full Text
Peer Reviewed
See detailRevisiting the SN1987A gamma-ray limit on ultralight axion-like particles
Payez, Alexandre ULg; Evoli, Carmelo; Fischer, Tobias et al

in Journal of Cosmology and Astroparticle Physics [= JCAP] (2015), 2015(02), 006

We revise the bound from the supernova SN1987A on the coupling of ultralight axion-like particles (ALPs) to photons. In a core-collapse supernova, ALPs would be emitted via the Primakoff process, and ... [more ▼]

We revise the bound from the supernova SN1987A on the coupling of ultralight axion-like particles (ALPs) to photons. In a core-collapse supernova, ALPs would be emitted via the Primakoff process, and eventually convert into gamma rays in the magnetic field of the Milky Way. The lack of a gamma-ray signal in the GRS instrument of the SMM satellite in coincidence with the observation of the neutrinos emitted from SN1987A therefore provides a strong bound on their coupling to photons. Due to the large uncertainty associated with the current bound, we revise this argument, based on state-of-the-art physical inputs both for the supernova models and for the Milky-Way magnetic field. Furthermore, we provide major amendments, such as the consistent treatment of nucleon-degeneracy effects and of the reduction of the nuclear masses in the hot and dense nuclear medium of the supernova. With these improvements, we obtain a new upper limit on the photon-ALP coupling: g_{a\gamma} < 5.3 x 10^{-12} GeV^{-1}, for m_a < 4.4 x 10^{-10} eV, and we also give its dependence at larger ALP masses. Moreover, we discuss how much the Fermi-LAT satellite experiment could improve this bound, should a close-enough supernova explode in the near future. [less ▲]

Detailed reference viewed: 18 (14 ULg)
Full Text
Peer Reviewed
See detail18F-FPRGD2 PET/CT imaging of integrin αvβ3 in renal carcinomas: Correlation with histopathology
WITHOFS, Nadia ULg; SIGNOLLE, NICOLAS; SOMJA, Joan ULg et al

in Journal of Nuclear Medicine (The) (2015)

Detailed reference viewed: 33 (7 ULg)
Full Text
Peer Reviewed
See detailQuaternary prevention, an answer of family doctors to overmedicalization
Jamoulle, Marc ULg

in International Journal of Health Policy and Management (2015), 4((X)), 1-4

In response to the questioning of Health Policy and Management (HPAM) by colleagues on the role of rank and file family physicians in the same journal, the author, a family physician in Belgium, is trying ... [more ▼]

In response to the questioning of Health Policy and Management (HPAM) by colleagues on the role of rank and file family physicians in the same journal, the author, a family physician in Belgium, is trying to highlight the complexity and depth of the work of his colleagues and their contribution to the understanding of the organization and economy of healthcare. It addresses, in particular, the management of health elements throughout the ongoing relationship of the family doctor with his/her patients. It shows how the three dimensions of prevention, clearly included in the daily work, are complemented with the fourth dimension, quaternary prevention or prevention of medicine itself, whose understanding could help to control the economic and human costs of healthcare [less ▲]

Detailed reference viewed: 368 (8 ULg)
Full Text
Peer Reviewed
See detailContribution to the Macrophytic Typology of Belgian Reference Watercourses
Galoux, Daniel; Cherot, Frédéric; Rosillon, Francis ULg et al

in Advances in Botany (2015), Volume 2015, Article ID 651369

The objective of the study is to create a typology of macrophytes for the reference watercourses of the Meuse River catchment ... [more ▼]

The objective of the study is to create a typology of macrophytes for the reference watercourses of the Meuse River catchment basininWalloniaasasteptowardstheimplementationoftheEuropeanWaterFrameworkDirective.The50sitesstudiedarethe objectofaphysicochemicalandenvironmentalcharacterizationfollowedbyafloristicsurvey(phanerogams,mosses,liverworts, andmacroalgae).Sixclustersofwatercourseswiththeircharacteristicspeciesarehighlightedbytwo-wayclusteringandindicator species. The abundance of phanerogams in some watercourses of the Arden region is not only linked to light intensity but also dependsonthedegreeofslopeandthenatureofthegeologicalsubstrate [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailEstimation of the Time Interval between the Administration of Heroin and the Sampling of Blood in Chronic Inhalers
DUBOIS, Nathalie ULg; HALLET, Claude ULg; SEIDEL, Laurence ULg et al

in Journal of Analytical Toxicology (2015)

To develop a model for estimating the time delay between last heroin consumption and blood sampling in chronic drug users. Eleven patients, all heroin inhalers undergoing detoxification, were included in ... [more ▼]

To develop a model for estimating the time delay between last heroin consumption and blood sampling in chronic drug users. Eleven patients, all heroin inhalers undergoing detoxification, were included in the study. Several plasma samples were collected during the detoxification procedure and analyzed for the heroin metabolites 6-acetylmorphine (6AM), morphine (MOR), morphine-6-glucuronide (M6G) and morphine-3-glucuronide (M3G), according to a UHPLC/MSMS method. The general linear mixed model was applied to time-related concentrations and a pragmatic four-step delay estimation approach was proposed based on the simultaneous presence of metabolites in plasma. Validation of the model was carried out using the jackknife technique on the 11 patients, and on a group of 7 test patients. Quadratic equations were derived for all metabolites except 6AM. The interval delay estimation was 2–4 days when only M3G present in plasma, 1–2 days when M6G and M3G were both present, 0–1 day when MOR, M6G and M3G were present and <2 h for all metabolites present. The ‘jackknife’ correlation between declared and actual estimated delays was 0.90. The overall precision of the delay estimates was 8–9 h. The delay between last heroin consumption and blood sampling in chronic drug users can be satisfactorily predicted from plasma heroin metabolites. [less ▲]

Detailed reference viewed: 31 (15 ULg)
Full Text
Peer Reviewed
See detailDifferential Performance between Two Timber Species in Forest Logging Gaps and in Plantations in Central Africa
Fayolle, Adeline ULg; Ouedraogo, Dakis-Yaoba ULg; Ligot, Gauthier ULg et al

in Forests (2015), 6(2), 380-394

To develop silvicultural guidelines for high-value timber species of Central African moist forests, we assessed the performance of the pioneer Milicia excelsa (iroko, Moraceae), and of the non-pioneer ... [more ▼]

To develop silvicultural guidelines for high-value timber species of Central African moist forests, we assessed the performance of the pioneer Milicia excelsa (iroko, Moraceae), and of the non-pioneer light demander Pericopsis elata (assamela, Fabaceae) in logging gaps and in plantations in highly degraded areas in south-eastern Cameroon. The survival and size of each seedling was regularly monitored in the silvicultural experiments. Differences in performance and allometry were tested between species in logging gaps and in plantations. The two species performance in logging gaps was significantly different from plantations and concurred with the expectations of the performance trade-off hypothesis but not with the expectations of species light requirements. The pioneer M. excelsa survived significantly better in logging gaps while the non-pioneer P. elata grew significantly faster in plantations. The high mortality and slow growth of M. excelsa in plantations is surprising for a pioneer species but could be explained by herbivory (attacks from a gall-making psyllid). Identifying high-value native timber species (i) with good performance in plantations such as P. elata is of importance to restore degraded areas; and (ii) with good performance in logging gaps such as M. excelsa is of importance to maintain timber resources and biodiversity in production forests. [less ▲]

Detailed reference viewed: 11 (2 ULg)
Full Text
Peer Reviewed
See detailMagnetic shielding of an inhomogenous magnetic field source by a bulk superconducting tube
Hogan, Kevin ULg; Fagnard, Jean-François ULg; Wera, Laurent ULg et al

in Superconductor Science and Technology (2015), 28(3), 035011

Bulk type-II irreversible superconductors can act as excellent passive magnetic shields, with a strong attenuation of low frequency magnetic fields. Up to now, the performances of superconducting magnetic ... [more ▼]

Bulk type-II irreversible superconductors can act as excellent passive magnetic shields, with a strong attenuation of low frequency magnetic fields. Up to now, the performances of superconducting magnetic shields have mainly been studied in a homogenous magnetic field, considering only immunity problems, i.e. when the field is applied outside the tube and the inner field should ideally be zero. In this paper, we aim to investigate experimentally and numerically the magnetic response of a high-Tc bulk superconducting hollow cylinder at 77 K in an emission problem, i.e. when subjected to the non-uniform magnetic field generated by a source coil placed inside the tube. A bespoke 3-D mapping system coupled with a 3-axis Hall probe is used to measure the magnetic flux density distribution outside the superconducting magnetic shield. A finite element model is developed to understand how the magnetic field penetrates into the superconductor and how the induced superconducting shielding currents flow inside the shield in the case where the emitting coil is placed coaxially inside the tube. The finite element modelling is found to be in excellent agreement with the experimental data. Results show that a concentration of the magnetic flux lines occurs between the emitting coil and the superconducting screen. This effect is observed both with the modelling and the experiment. In the case of a long tube, we show that the main features of the field penetration in the superconducting walls can be reproduced with a simple analytical 1D model. This model is used to estimate the maximum flux density of the emitting coil that can be shielded by the superconductor. [less ▲]

Detailed reference viewed: 32 (18 ULg)
Full Text
Peer Reviewed
See detailThe non-convex shape of (234) Barbara, the first Barbarian
Tanga, Paolo; Carry, B.; Colas, F. et al

in Monthly Notices of the Royal Astronomical Society (2015)

Asteroid (234) Barbara is the prototype of a category of asteroids that has been shown to be extremely rich in refractory inclusions, the oldest material ever found in the Solar System. It exhibits ... [more ▼]

Asteroid (234) Barbara is the prototype of a category of asteroids that has been shown to be extremely rich in refractory inclusions, the oldest material ever found in the Solar System. It exhibits several peculiar features, most notably its polarimetric behavior. In recent years other objects sharing the same property (collectively known as ”Barbarians”) have been discovered. Interferometric observations in the mid-infrared with the ESO VLTI suggested that (234) Barbara might have a bi-lobated shape or even a large companion satellite. We use a large set of 57 optical lightcurves acquired between 1979 and 2014, together with the timings of two stellar occultations in 2009, to determine the rotation period, spin-vector coordinates, and 3-D shape of (234) Barbara, using two different shape reconstruction algorithms. By using the lightcurves combined to the results obtained from stellar occultations, we are able to show that the shape of (234) Barbara exhibits large concave areas. Possible links of the shape to the polarimetric properties and the object evolution are discussed. We also show that VLTI data can be modeled without the presence of a satellite [less ▲]

Detailed reference viewed: 24 (8 ULg)
Full Text
Peer Reviewed
See detailA Review of Pharmaceutical Extrusion: Critical Process Parameters and Scaling-up
Thiry, Justine ULg; Krier, Fabrice ULg; Evrard, Brigitte ULg

in International Journal of Pharmaceutics (2015), 479(1), 227-240

Hot melt extrusion has been a widely used process in the pharmaceutical area for three decades. In this field, it is important to optimize the formulation in order to meet specific requirements. However ... [more ▼]

Hot melt extrusion has been a widely used process in the pharmaceutical area for three decades. In this field, it is important to optimize the formulation in order to meet specific requirements. However, the process parameters of the extruder should be as much investigated as the formulation since they have a major impact on the final product characteristics. Moreover, a design space should be defined in order to obtain the expected product within the defined limits. This gives some freedom to operate as long as the processing parameters stay within the limits of the design space. Those limits can be investigated by varying randomly the process parameters but it is recommended to use design of experiments. An examination of the literature is reported in this review to summarize the impact of the variation of the process parameters on the final product properties. Indeed, the homogeneity of the mixing, the state of the drug (crystalline or amorphous), the dissolution rate, the residence time, can be influenced by variations in the process parameters. In particular, the impact of the following process parameters: temperature, screw design, screw speed and feeding, on the final product, has been reviewed. [less ▲]

Detailed reference viewed: 34 (14 ULg)
Full Text
Peer Reviewed
See detailEconomics of a decision-support system for managing the main fungal diseases of winter wheat in the Grand-Duchy of Luxembourg
El Jarroudi, Moussa ULg; Kouadio, Louis; Beyer, Marco et al

in Field Crops Research (2015), 172(2), 32-41

We evaluated the cost effectiveness of a decision-support system (DSS) developed for assessing in real time the risk of progression of the main fungal diseases (i.e., Septoria leaf blotch, powdery mildew ... [more ▼]

We evaluated the cost effectiveness of a decision-support system (DSS) developed for assessing in real time the risk of progression of the main fungal diseases (i.e., Septoria leaf blotch, powdery mildew, leaf rusts and Fusarium head blight) of winter wheat in the Grand-Duchy of Luxembourg (GDL). The study was conducted in replicated field experiments located in four agricultural locations (representative of the main agro-ecological regions of the country) over a 10-year period (2003-2012). Three fungicide spray strategies were compared: a single DSS-based system and two commonly used spray practices in the GDL, a double- (2T)- and a triple- spray (3T) spray treatment; there was also a non-treated control. In years with a high disease pressure, the DSS-based recommendation resulted in protection of the three upper leaves comparable to that achieved with the 2T and 3T treatments, with significant grain yield increases (P > 0.05) compared to the control (a 4 to 42% increase, depending on the site and year). Overall, the financial gain in treated plots compared with the control ranged from 3 to 16% at the study sites. Furthermore, in seasons when dry weather conditions precluded epidemic development, no the DSS-basedDSS recommended no fungicide spray was recommended, reducing use of fungicide, and thus saving the cost of the product. The gain in yield for the 2T and 3T plots (compared with control) did not necessarily result in a financial gain during the duration of the experiment. This study demonstrates the potential advantages and profitability of using a DSS -based approach for disease management. [less ▲]

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailNew spectroscopic and polarimetric observations of the A0 supergiant HD 92207
Hubrig, S.; Kholtygin, A. F.; Schöller, M. et al

in Astronomische Nachrichten (2015), 336

Our recent search for the presence of a magnetic field in the bright early A-type supergiant HD 92207 using FORS 2 in spectropolarimetric mode revealed the presence of a longitudinal magnetic field of the ... [more ▼]

Our recent search for the presence of a magnetic field in the bright early A-type supergiant HD 92207 using FORS 2 in spectropolarimetric mode revealed the presence of a longitudinal magnetic field of the order of a few hundred Gauss. However, the definite confirmation of the magnetic nature of this object remained pending due to the detection of short-term spectral variability probably affecting the position of line profiles in left- and right-hand polarized spectra. We present new magnetic field measurements of HD 92207 obtained on three different epochs in 2013 and 2014 using FORS 2 in spectropolarimetric mode. A 3σ detection of the mean longitudinal magnetic field using the entire spectrum, <B_z>_all=104±34 G, was achieved in observations obtained in 2014 January. At this epoch, the position of the spectral lines appeared stable. Our analysis of spectral line shapes recorded in opposite circularly polarized light, i.e. in light with opposite sense of rotation, reveals that line profiles in the light polarized in a certain direction appear slightly split. The mechanism causing such a behaviour in the circularly polarized light is currently unknown. Trying to settle the issue of short-term variability, we searched for changes in the spectral line profiles on a time scale of 8-10 min using HARPS polarimetric spectra and on a time scale of 3-4 min using time series obtained with the CORALIE spectrograph. No significant variability was detected on these time scales during the epochs studied. Based on observations collected with the CORALIE echelle spectrograph mounted on the 1.2-m Swiss telescope at La Silla Observatory, data obtained at the European Southern Observatory (ESO Prg. 092.D-0209(A), and data obtained from the ESO Science Archive Facility under request MSCHOELLER 102067). [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailThe summer 2012 Greenland heat wave: in situ and remote sensing observations of water vapour isotopic composition during an atmospheric river event†
Bonne, JL; Steen-Larsen, HC; Risi, C. et al

in Journal of Geophysical Research. Atmospheres (2015)

During July 7-12, 2012, extreme moist and warm conditions occurred over Greenland, leading to widespread surface melt. To investigate the physical processes during the atmospheric moisture transport of ... [more ▼]

During July 7-12, 2012, extreme moist and warm conditions occurred over Greenland, leading to widespread surface melt. To investigate the physical processes during the atmospheric moisture transport of this event, we study the water vapour isotopic composition using surface in situ observations in Bermuda Island, South Greenland coast (Ivittuut) and Northwest Greenland ice sheet (NEEM), as well as remote sensing observations (IASI instrument on-board MetOp-A), depicting propagation of similar surface and mid-tropospheric humidity and δD signals. Simulations using Lagrangian moisture source diagnostic and water tagging in a regional model showed that Greenland was affected by an atmospheric river transporting moisture from the western subtropical North Atlantic Ocean, which is coherent with observations of snow pit impurities deposited at NEEM. At Ivittuut, surface air temperature, humidity and δD increases are observed. At NEEM, similar temperature increase is associated with a large and long-lasting ~100 δD enrichment and ~15 deuterium excess decrease, thereby reaching Ivittuut level. We assess the simulation of this event in two isotope-enabled atmospheric general circulation models (LMDz-iso and ECHAM5-wiso). LMDz-iso correctly captures the timing of propagation for this event identified in IASI data but depict too gradual variations when compared to surface data. Both models reproduce the surface meteorological and isotopic values during the event but underestimate the background deuterium excess at NEEM. Cloud liquid water content parametrization in LMDz-iso poorly impacts the vapour isotopic composition. Our data demonstrate that during this atmospheric river event the deuterium excess signal is conserved from the moisture source to Northwest Greenland. [less ▲]

Detailed reference viewed: 25 (1 ULg)
Full Text
Peer Reviewed
See detailA comparison between visual estimates and image analysis measurements to determine Septoria leaf blotch severity in winter wheat
El Jarroudi, Moussa ULg; Kouadio, Louis; Mackels, Christophe et al

in Plant Pathology (2015)

Methods to estimate disease severity vary in accuracy, reliability, ease of use and cost. Severity of Septoria leaf blotch (SLB, caused by Zymoseptoria graminicola) was estimated by four raters and by ... [more ▼]

Methods to estimate disease severity vary in accuracy, reliability, ease of use and cost. Severity of Septoria leaf blotch (SLB, caused by Zymoseptoria graminicola) was estimated by four raters and by image analysis (assumed actual values) on individual leaves of winter wheat in order to explore accuracy and reliability of estimates, and to ascertain whether there were any general characteristics of error. Specifically, (i) we determined the accuracy and reliability of visual assessments of SLB over the full range of severity from 0 to 100%, and we investigated (ii) whether certain 10% ranges in actual disease severity between 0 and 100% were more prone to estimation error compared with others, and (iii) whether leaf position affected accuracy within those ranges. Lin's concordance correlation analysis of all severities (0 to 100%) demonstrated that all raters had estimates close to the actual values (agreement: ρc = 0.92-0.99). However, agreement between actual SLB severities and estimates by raters was less good when compared over short 10% subdivisions within the 0-100% range (ρc = -0.12 to 0.99). Despite common rater imprecision at estimating low and high SLB severities, individual raters differed considerably in their accuracy over the short 10% subdivisions. There was no effect of leaf position on accuracy or precision of severity estimate on separate leaves (L1-L3). Pursuing efforts in understanding error in disease estimation should aid in improving the accuracy of assessments, making visual estimates of disease severity more useful for research and applied purposes. [less ▲]

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailTRAPPIST monitoring of comet C/2012 F6 (Lemmon)
Opitom, Cyrielle ULg; Jehin, Emmanuel ULg; Manfroid, Jean ULg et al

in Astronomy and Astrophysics (2015), 574

We report the results of the long-term narrowband photometry and imaging monitoring of comet C/2012 F6 (Lemmon) with the robotic TRAPPIST telescope (La Silla Observatory). Observations covered 52 nights ... [more ▼]

We report the results of the long-term narrowband photometry and imaging monitoring of comet C/2012 F6 (Lemmon) with the robotic TRAPPIST telescope (La Silla Observatory). Observations covered 52 nights pre- and post-perihelion between December 11, 2012, and June 11, 2013 (perihelion: 24 March, 2013). We followed the evolution of the OH, NH, CN, C[SUB]3[/SUB], and C[SUB]2[/SUB] production rates computed with the Haser model as well as the evolution of the A(θ)fρ parameter as a proxy for the dust production. All five gas species display similar slopes for the heliocentric dependence. An asymmetry about perihelion is observed, the rate of brightening being steeper than the rate of fading. The chemical composition of the comet's coma changes slightly along the orbit: the relative abundance of C[SUB]2[/SUB] to CN increases with the heliocentric distance (r) below -1.4 au and decreases with r beyond 1.4 au while the C[SUB]3[/SUB]-to-CN ratio is constant during our observations. The behavior of the dust is different from that of the gas, the slope of the heliocentric dependence becoming steeper in early February, correlated to a change in the visual lightcurve slope. However, the dust color does not vary during the observations. The application of several enhancement techniques on the images revealed structures in the CN, C[SUB]3[/SUB], and C[SUB]2[/SUB] images. These features imply the existence of one or several active zone(s) on the comet nucleus. The shape of the structures is similar in these three filters and changes from a roughly hourglass shape in December and January to a corkscrew shape in February and March. The structures in the continuum filters (sampling the dust) are not correlated to those observed for the gas. During several full nights in February, we observed changes in the CN and C[SUB]2[/SUB] structures that repeated periodically because of the nucleus rotation, our derived rotational period being of 9.52 ± 0.05 h. Full Tables 2, 4, 6 are only available at the CDS via anonymous ftp to <A href="http://cdsarc.u-strasbg.fr">http://cdsarc.u-strasbg.fr</A> (ftp://130.79.128.5) or via <A href="http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/574/A38">http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/574/A38</A> [less ▲]

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailSelf-assembly of a triblock terpolymer mediated by hydrogen-bonded complexes
Guerlain, Claire; Piogé, Sandie; Detrembleur, Christophe ULg et al

in Journal of Polymer Science. Part A, Polymer Chemistry (2015), 53(3), 459-467

A poly(methyl methacrylate)-block-poly(4-vinylpyridine)-block-polystyrene (PMMA-b-P4VP-b-PS) triblock terpolymer is synthesized by ATRP to study its self-assembly with PAA in organic solvents. The self ... [more ▼]

A poly(methyl methacrylate)-block-poly(4-vinylpyridine)-block-polystyrene (PMMA-b-P4VP-b-PS) triblock terpolymer is synthesized by ATRP to study its self-assembly with PAA in organic solvents. The self-assembly behavior of this system is compared with the one of a mixture of two diblocks, namely polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) and poly(methyl methacrylate)-block-poly(methacrylic acid) (PMMA-b-PMAA). For both systems, formation of hydrogen-bonded complexes between the P4VP and PMAA or PAA blocks occurs. These complexes become insoluble in the solvent used and micelles with a P4VP/P(M)AA complexes core surrounded by PS and PMMA coronal chains are obtained in both cases. These micelles are analyzed by DLS and TEM. Spherical micelles are formed for both systems but the hydrodynamic radii obtained for the two types of micelles are different. Indeed, the micelles formed by the PMMA-b-P4VP-b-PS + PAA system are smaller than those observed for the PS-b-P4VP + PMMA-b-PMAA system. Finally, the effect of the molar ratio of the P4VP/PMAA complexing blocks is investigated. [less ▲]

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailA revised DR Congo mining code could lead to a decrease in Chinese investment in the country
Wintgens, Sophie ULg

in Africa at LSE (2015)

As China shows indications of being willing to fall in line with international standards on procuring conflict minerals, this article examines the strategic issues facing China as DR Congo seeks to revise ... [more ▼]

As China shows indications of being willing to fall in line with international standards on procuring conflict minerals, this article examines the strategic issues facing China as DR Congo seeks to revise its mining code. [less ▲]

Detailed reference viewed: 19 (4 ULg)
Full Text
Peer Reviewed
See detailLa thermoplastie bronchique dans le traitement de l'asthme sévère de l'adulte.
Chanez, P.; Boulet, L.-P.; Brillet, P.-Y. et al

in Revue des maladies respiratoires (2015), 32

Bronchial thermoplasty is a recent endoscopic technique for the treatment of severe asthma. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since ... [more ▼]

Bronchial thermoplasty is a recent endoscopic technique for the treatment of severe asthma. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since this is a device-based treatment, the evaluation procedure of risks and benefits is different that for pharmaceutical products; safety aspects, regulatory requirements, study design and the assessment of the magnitude of effects may all be different. The mechanism of action and optimal patient selection need to be assessed further in rigorous clinical and scientific studies. This technique is in harmony with the development of personalised medicine in the 21st century. It should be developed further in response to the numerous challenges and needs not yet met in the management of severe asthma. [less ▲]

Detailed reference viewed: 37 (14 ULg)
Full Text
Peer Reviewed
See detailEpidémiologie de la lithiase urinaire sur base d'une analyse morpho-constitutionnelle
Castiglione, Vincent ULg; JOURET, François ULg; Bruyère, Olivier ULg et al

in Néphrologie & Thérapeutique (2015), 11

Urolithiasis is a common condition, with a prevalence of 10% and a male/female ratio above 1 according to large national series. Various types of urinary stones have been described upon their mineral ... [more ▼]

Urolithiasis is a common condition, with a prevalence of 10% and a male/female ratio above 1 according to large national series. Various types of urinary stones have been described upon their mineral content and/or their morphology. Hence, a combined morpho-constitutional (M-C) classification has been proposed. In order to detail the prevalence of urolithiasis in general and of each M-C type in particular upon age and gender in Belgium, we retrospectively studied the database of a reference center for urolithiasis analysis. Between 2010 and 2013, 2195 stones were characterized. We excluded 45 nonbiological stones and 281 stones, which originated from outside the study zone. Among 1869 stones,1293 (69.2%) affected men. Prevalence peak of urolithiasis was observed between 50–60 years of age in both genders. The M-C analysis was available for 1854 stones (99.2%): multiple morphological types were concomitantly identified in 49.3%. In the whole population, the main mineral constituent was whewellite (54.4%), mainly organized as type Ia (94%). Weddellite was found in 19.8%, with an equal distribution between types IIa and IIb. Uric acid was the 3rd most frequent constituent in man, with a similar distribution between IIIa and IIIb. Phosphate was uncommon in man (8.2%), but frequent in woman (26.6%) with a type IVa1 organization. Prevalence of M-C types changes with aging, i.e. decrease of weddellite and increase of whewellite and uric acid in both genders. This retrospective analysis of a single-center database of urinary stones helps characterize the M-C epidemiology of urolithiasis in Belgium. [less ▲]

Detailed reference viewed: 50 (30 ULg)
Full Text
Peer Reviewed
See detailConsommation de pornographie à l’adolescence : quelles représentations de la sexualité et de la pornographie, pour quelle sexualité ?
Puglia, Rosa ULg; Glowacz, Fabienne ULg

in Neuropsychiatrie de l'Enfance et de l'Adolescence (2015)

Cette recherche, réalisée sur une population de 319 adolescents (150 filles et 169 garçons) âgés de 15 à 19 ans, présente deux grands objectifs. Premièrement, elle vise à évaluer l’impact de ... [more ▼]

Cette recherche, réalisée sur une population de 319 adolescents (150 filles et 169 garçons) âgés de 15 à 19 ans, présente deux grands objectifs. Premièrement, elle vise à évaluer l’impact de l’accessibilité et de la visualisation de la pornographie au niveau des représentations de ce média et de la sexualité. Deuxièmement, elle vise à évaluer l’influence de la consommation pornographique au niveau du développement psycho-sexuel des adolescents. Un protocole comprenant plusieurs dimensions telles que les relations sentimentales, la sexualité, la pornographie, et les représentations a été administré aux participants de manière groupale et anonyme. Il en ressort que les adolescents consommateurs de pornographie soulignent davantage les effets positifs associés à la pornographie, qu’ils reconnaissent une influence de ce média sur leur vie sexuelle et qu’ils adoptent des pratiques sexuelles plus diversifiées que celles de leurs pairs non-consommateurs. En revanche, consommateurs et non-consommateurs soulignent de manière identique les effets négatifs associés à ce média. Cette conscientisation des effets négatifs aurait un effet modérateur sur l’influence de la pornographie. Actuellement, la consommation de pornographie est un comportement expérimenté par une majorité d’adolescents ; elle pourrait s’inscrire dans un processus développemental adolescentaire et se comprendre comme une conduite exploratoire répondant à diverses fonctions dont la recherche de repères au niveau de la sexualité. [less ▲]

Detailed reference viewed: 50 (11 ULg)
Full Text
Peer Reviewed
See detailB fields in OB stars (BOB): on the detection of weak magnetic fields in the two early B-type stars beta CMa and epsilon CMa
Fossati, L.; Castro, N.; Morel, Thierry ULg et al

in Astronomy and Astrophysics (2015), 574

Within the context of the "B fields in OB stars (BOB)" collaboration, we used the HARPSpol spectropolarimeter to observe the early B-type stars beta CMa (HD44743; B1 II/III) and epsilon CMa (HD52089; B1.5 ... [more ▼]

Within the context of the "B fields in OB stars (BOB)" collaboration, we used the HARPSpol spectropolarimeter to observe the early B-type stars beta CMa (HD44743; B1 II/III) and epsilon CMa (HD52089; B1.5 II). For both stars, we consistently detected the signature of a weak (<30 G in absolute value) longitudinal magnetic field. We determined the physical parameters of both stars and characterise their X-ray spectrum. For beta CMa, our mode identification analysis led to determining a rotation period of 13.6+/-1.2 days and of an inclination angle of the rotation axis of 57.6+/-1.7 degrees, with respect to the line of sight. On the basis of these measurements and assuming a dipolar field geometry, we derived a best fitting obliquity of ~22 degrees and a dipolar magnetic field strength (Bd) of ~100 G (60<Bd<230 G within 1 sigma), below what is typically found for other magnetic massive stars. For epsilon CMa we could only determine a lower limit on the dipolar magnetic field strength of 13 G. For this star, we determine that the rotation period ranges between 1.3 and 24 days. Both stars are expected to have a dynamical magnetosphere. We also conclude that both stars are most likely core hydrogen burning and that they have spent more than 2/3 of their main sequence lifetime. A histogram of the distribution of the dipolar magnetic field strength for the magnetic massive stars known to date does not show the magnetic field "desert" observed instead for intermediate-mass stars. The biases involved in the detection of (weak) magnetic fields in massive stars with the currently available instrumentation and techniques imply that weak fields might be more common than currently observed. Our results show that, if present, even relatively weak magnetic fields are detectable in massive stars and that more observational effort is probably still needed to properly access the magnetic field incidence. [less ▲]

Detailed reference viewed: 20 (4 ULg)
Full Text
Peer Reviewed
See detailExploring new dimensions in cadaveric decomposition odour analysis
Stefanuto, Pierre-Hugues ULg; Perrault, Katelynn; Lloyd, Rebecca et al

in Analytical Methods (2015), 7

This study demonstrates the first documented use of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS) for volatile organic compound ... [more ▼]

This study demonstrates the first documented use of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS) for volatile organic compound analysis in the forensic sciences. High-resolution mass spectral data provided higher confidence in analyte identification. GC×GC-HRTOFMS will be valuable for future studies of decomposition odour and other complex volatile matrices. [less ▲]

Detailed reference viewed: 23 (7 ULg)
Full Text
Peer Reviewed
See detailSystematic qualitative review of randomised trials conducted in nonsmall cell lung cancer with a noninferiority or equivalence design
Paesmans, Marianne; Grigoriu, Bogdan; Ocak, Sebahat et al

in European Respiratory Journal (2015), 45(2), 511-524

The use of noninferiority randomised trials for patients with advanced non-small cell lung cancer has emerged during the past 10–15 years but has raised some issues related to their justification and ... [more ▼]

The use of noninferiority randomised trials for patients with advanced non-small cell lung cancer has emerged during the past 10–15 years but has raised some issues related to their justification and methodology. The present systematic review aimed to assess trial characteristics and methodological aspects. All randomised clinical trials with a hypothesis of noninferiority/equivalence, published in English, were identified. Several readers extracted a priori defined methodological information. A qualitative analysis was then performed. We identified 20 randomised clinical trials (three phase II and 17 phase III), 11 of them being conducted in strong collaboration with industry. We highlighted some deficiencies in the reports like the lack of justification for both the noninferiority assumption and the definition of the noninferiority margin, as well as inconsistencies between the results and the authors’ conclusions. CONSORT guidelines were better followed for general items than for specific items (p<0.001). Improvement in the reporting of the meth"odology of noninferiority/equivalence trials is needed to avoid misleading interpretation and to allow readers to be fully aware of the assumptions underlying the trial designs. They should be restricted to limited specific situations with a strong justification why a noninferiority hypothesis is acceptable. [less ▲]

Detailed reference viewed: 11 (2 ULg)
Full Text
Peer Reviewed
See detailLittérature et sémiotique: histoire et épistémologie
Provenzano, François ULg; Bertrand, Jean-Pierre ULg; Stienon, Valérie ULg

in Signata. Annales des Sémiotiques = Annals of Semiotics (2015), 5(2014), 384

La question des liens entre sémiotique et littérature amène à poser un regard rétrospectif sur une période qui paraît aujourd’hui révolue. L’émergence de la sémiotique comme discipline institutionnalisée ... [more ▼]

La question des liens entre sémiotique et littérature amène à poser un regard rétrospectif sur une période qui paraît aujourd’hui révolue. L’émergence de la sémiotique comme discipline institutionnalisée est en effet contemporaine d’un profond changement de paradigme dans les approches du texte littéraire. Au cours de la décennie 1960, la rencontre entre sémiotique et littérature produit, en un temps très bref, un nombre considérable de concepts et d’instruments d’analyse, qui vont de la théorie du dialogisme et de la polyphonie à la sémanalyse en passant par la narratologie et la sémantique structurale. L'objectif de ce dossier est de saisir cette rencontre dans la perspective d’une histoire des idées, en éclairant ce qui, dans la conjoncture des années 1960, a pu favoriser la convergence, avant de la rendre caduque ou obsolète. Une place est également réservée aux témoignages pour laisser entendre, dans un souci d'historicisation, la voix d'acteurs importants de ces années sémio-littéraires: Philippe Hamon, le groupe Mu, Marc Angenot [less ▲]

Detailed reference viewed: 31 (2 ULg)
Full Text
Peer Reviewed
See detailImpact of roughness and circularity-defect on bridge cables stability
Benidir, Adel; Flamand, Olivier; Gaillet, Laurent et al

in Journal of Wind Engineering & Industrial Aerodynamics (2015), 137

The stay cables on cable-stayed bridges have been the subject of considerable research in order to understand the origins of the dry galloping phenomenon. Surface irregularity is one of the last ... [more ▼]

The stay cables on cable-stayed bridges have been the subject of considerable research in order to understand the origins of the dry galloping phenomenon. Surface irregularity is one of the last parameters that have not been thoroughly examined. This paper focuses on static wind tunnel tests on original High Density Polyethylene cable covers in a range of Reynolds numbers from the sub-critical regime to the critical, corresponding to values ranging from Re = 9.6x104 to Re = 3.3x105. The experiment consists in testing cable covers of various diameters in order to investigate the effect of surface irregularity (roughness and circularity defect) on the mechanism of dry galloping excitation. Previous studies reported that dry galloping is caused by the appearance of a negative pressure bubble on one side of the circular cylinder at the critical Reynolds number range, leading to a rapid drop in the drag coefficient and the appearance of a non-negligible lift force. The results of the present investigation demonstrate that there is a clear correlation between the single bubble pressure pattern and the circularity defect along the tube. They further show that surface roughness has little effect on the location of the bubble. The paper also treats the spatial and temporal correlation of the instantaneous pressure pattern along the tube with respect to the circularity defect. [less ▲]

Detailed reference viewed: 32 (1 ULg)
Full Text
Peer Reviewed
See detailEvaluation of Water Resources Quality in Sabodala Gold Mining Region and Its Surrounding Area (Senegal)
Mall, Ibrahima; Diaw, Moctar; Dieng, Ndeye Maguette ULg et al

in Journal of Water Resource and Protection (2015), 7(3), 247-263

Geochemical and Geostatistical tools were used to assess: 1) the chemical quality and, geochemical processes in crystalline rock aquifers in Sabodala (Eastern Senegal) and its surroundings and 2) the ... [more ▼]

Geochemical and Geostatistical tools were used to assess: 1) the chemical quality and, geochemical processes in crystalline rock aquifers in Sabodala (Eastern Senegal) and its surroundings and 2) the impact of mining activities on their quality. A total of 26 water samples collected at boreholes, dug wells and stream, were analyzed to determine major and trace elements concentration focused on elements that represent more threats on human health. Boxplots define chemical characteristics of water for each aquifer formation compared to surface waters. Geostatistical analysis show two sources of water mineralization with regard to major elements: a first natural source characterized by Ca-Mg-HCO3 water type from boreholes and unpolluted surface water and a second group characterized by polluted water by nitrates with Na-NO3-Cl type mainly observed in upper weathered aquifers. However, considering trace element, geostatistical analysis showed three water groups: water with very low trace element concentrations encountered in boreholes and unpolluted surface waters, and waters with relatively high trace element concentrations such as Al observed in areas affected by gold mining activities and finally, polluted waters by Ni, Co, Mn and Cr observed at Sabodala. Results show that in eastern Senegal well waters are vulnerable and often affected by pollution. [less ▲]

Detailed reference viewed: 20 (4 ULg)
Full Text
Peer Reviewed
See detailManagement and systemic treatment of clear cell metastatic renal cell carcinoma: BSMO expert panel recommendations
El Ali, Z; Van Brummelen, D; Wolter, P et al

in Belgian Journal of Medical Oncology [=BJMO] (2015), 9(1),

Detailed reference viewed: 16 (0 ULg)
Full Text
Peer Reviewed
See detailLe dosage de la vitamine D: considérations pré-analytiques et analytiques
LE GOFF, Caroline ULg; Souberbielle, Jean-Claude; Delvin, Edgard et al

in Annales de Biologie Clinique (2015), 73(1), 79-92

The constantly increasing requests for the measurement of serum 25-hydroxyvitamin D over the last years has led reagent manufacturers to market different automated and semi-automated methods, that being ... [more ▼]

The constantly increasing requests for the measurement of serum 25-hydroxyvitamin D over the last years has led reagent manufacturers to market different automated and semi-automated methods, that being unfortunately not fully harmonized, yield different results. Liquid chromatography coupled to tandem mass spectrometry has more recently been introduced. This approach allows the distinction between the two forms of 25-hydroxyvitamin D and to measure other metabolites. This approach also requires harmonization to curtail the differences between the different analytical methods. To meet this requirement, the American national institutes of health (NIH), the CDC (Center for disease control and prevention) in Atlanta, the NIST (National institute of standards and technology) and the vitamin D Reference laboratory of Ghent University have pooled their expertise to develop a standardization program. This article reviews the main elements and the difficulties of the automated and semi-automated methods for 25-hydroxyvitamin D, from sample preparation to the analytical phase, as well as those related to mass spectrometry. It also addresses the issues related to the clinical decision thresholds and the possibility of measurements in different biological liquids. [less ▲]

Detailed reference viewed: 19 (9 ULg)
Full Text
Peer Reviewed
See detailHow to Assess Data Availability, Accessibility and Format for Risk Analysis?
Humblet, Marie-France ULg; Vandeputte, Sébastien; Mignot, Clémence et al

in Transboundary and Emerging Diseases (2015), doi: 10.1111/tbed.12328

Risk assessments are mostly carried out based on available data, which do not reflect all data theoretically required by experts to answer them. This study aimed at developing a methodology to assess data ... [more ▼]

Risk assessments are mostly carried out based on available data, which do not reflect all data theoretically required by experts to answer them. This study aimed at developing a methodology to assess data availability, accessibility and format, based on a scoring system and focusing on two diseases: Venezuelan equine encephalomyelitis (VEE), still exotic to Europe, and alveolar echinococcosis, caused by Echinococcus multilocularis (EM), endemic in several Member States (MSs). After reviewing 36 opinions of the EFSA-AHAW Panel on risk assessment of animal health questions, a generic list of needed data was elaborated. The methodology consisted, first, in implementing a direct and an indirect survey to collect the data needed for both case studies: the direct survey consisted in a questionnaire sent to contact points of three European MSs (Belgium, France and the Netherlands), and the organization of a workshop gathering experts on both diseases. The indirect survey, focusing on the three MSs involved in the direct survey plus Spain, relied on web searches. Secondly, a scoring system with reference to data availability, accessibility and format was elaborated, to, finally, compare both diseases and data between MSs. The accessibility of data was generally related to their availability. Web searches resulted in more data available for VEE compared to EM, despite its current exotic status in the European Union. Hypertext markup language and portable document files were the main formats of available data. Data availability, accessibility and format should be improved for research scientists/assessors. The format of data plays a key role in the feasibility and rapidness of data management and analysis, through a prompt compilation, combination and aggregation in working databases. Harmonization of data collection process is encouraged, according to standardized procedures, to provide useful and reliable data, both at the national and the international levels for both animal and human health; it would allow assessing data gaps through comparative studies. The present methodology is a good way of assessing the relevance of data for risk assessment, as it allows integrating the uncertainty linked to the quality of data used. Such an approach could be described as transparent and traceable and should be performed systematically. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailDe- and Re-Institutionalizing Technology Assessment in Contemporary Knowledge-Based Economies
Delvenne, Pierre ULg; Charlier, Nathan ULg; Rosskamp, Benedikt ULg et al

in Technikfolgenabschätzung - Theorie und Praxis (2015), 24(1), 130

This article illuminates the potential role of technology assessment (TA) in knowl- edge-driven science, technology and inno- vation (STI) regimes by providing a compar- ative review of Flemish and ... [more ▼]

This article illuminates the potential role of technology assessment (TA) in knowl- edge-driven science, technology and inno- vation (STI) regimes by providing a compar- ative review of Flemish and Walloon TA. It draws critical attention to the ways in which TA actors and institutes in Flanders and Wal- lonia position themselves, or are positioned, in relation to dominant innovation policies and large-scale political transformations, notably the convergence of STI around the knowledge-based economy (KBE) and the regionalization of STI policy in Belgium. The article’s findings shed light on the Flemish government’s recent decision to close its parliamentary TA institute and the institution- al expansion of TA in Wallonia and elsewhere in Europe. It argues that TA has politics, as TA in Flanders and Wallonia aligns with the advent of strategic science and is also affil- iated to specific political parties. As these considerations run counter to the dominant representation of TA as a neutral governance tool that serves the needs of all STI decision makers, they draw into question the viability and utility of TA within contemporary KBEs. [less ▲]

Detailed reference viewed: 30 (3 ULg)
Full Text
Peer Reviewed
See detailOn modular decompositions of system signatures
Marichal, Jean-Luc; Mathonet, Pierre ULg

in Journal of Multivariate Analysis (2015), 134

Considering a semicoherent system made up of $n$ components having i.i.d. continuous lifetimes, Samaniego defined its structural signature as the $n$-tuple whose $k$-th coordinate is the probability that ... [more ▼]

Considering a semicoherent system made up of $n$ components having i.i.d. continuous lifetimes, Samaniego defined its structural signature as the $n$-tuple whose $k$-th coordinate is the probability that the $k$-th component failure causes the system to fail. This $n$-tuple, which depends only on the structure of the system and not on the distribution of the component lifetimes, is a very useful tool in the theoretical analysis of coherent systems. It was shown in two independent recent papers how the structural signature of a system partitioned into two disjoint modules can be computed from the signatures of these modules. In this work we consider the general case of a system partitioned into an arbitrary number of disjoint modules organized in an arbitrary way and we provide a general formula for the signature of the system in terms of the signatures of the modules. The concept of signature was recently extended to the general case of semicoherent systems whose components may have dependent lifetimes. The same definition for the $n$-tuple gives rise to the probability signature, which may depend on both the structure of the system and the probability distribution of the component lifetimes. In this general setting, we show how under a natural condition on the distribution of the lifetimes, the probability signature of the system can be expressed in terms of the probability signatures of the modules. We finally discuss a few situations where this condition holds in the non-i.i.d. and nonexchangeable cases and provide some applications of the main results. [less ▲]

Detailed reference viewed: 20 (0 ULg)
Full Text
Peer Reviewed
See detailLes états spatio-temporels d'existence et de présence
Hallot, Pierre ULg; Stewart, Kathleen; Billen, Roland ULg

in Revue Internationale de Géomatique = International Journal of Geomatics and Spatial Analysis (2015), 25(2), 173-196

This paper addresses a new approach to formalize the spatiotemporal relationships between geographical objects that do not exist or that are not present at the time of the analysis. We propose first an ... [more ▼]

This paper addresses a new approach to formalize the spatiotemporal relationships between geographical objects that do not exist or that are not present at the time of the analysis. We propose first an analysis of the spatiotemporal states of existence and presence for a geographical object. Then, we combine the spatiotemporal states to define a comprehensive set of life and motion configuration. The proposed model serves as formal basis to perform spatiotemporal queries by retrieving selected patterns in the life and motion configurations. The research is applied to the organization of a scientific conference, in doing so we are able to define the relationships that exist between an event located in space and time and mobiles objects evolving within the space, i.e. the conference participants. [less ▲]

Detailed reference viewed: 53 (14 ULg)
Full Text
Peer Reviewed
See detailLa cardiomyopathie du cirrhotique : un bref aperçu
MARCHETTA, Stella ULg; DELWAIDE, Jean ULg; LANCELLOTTI, Patrizio ULg

in Revue Médicale de Liège (2015), 2

Detailed reference viewed: 32 (3 ULg)
Full Text
Peer Reviewed
See detailIncreased tree-growth synchronization of beech (Fagus sylvatica L.) in response to climate change in northwestern Europe
Latte, Nicolas ULg; Lebourgeois, François; Claessens, Hugues ULg

in Dendrochronologia (2015), 33

To better understand how the radial growth of beech (Fagus sylvatica L.) high forests has responded to climate change, we selected 12 sites (137 trees) with optimal growing conditions along a W − E ... [more ▼]

To better understand how the radial growth of beech (Fagus sylvatica L.) high forests has responded to climate change, we selected 12 sites (137 trees) with optimal growing conditions along a W − E altitudinal gradient (67–590 m) in Belgium. We evaluated temporal changes in growth response to climate by using pointer year analysis, moving mean sensitivities (1860–2011), and moving bootstrapped correlation coefficients (1952–2011). The strongest driving climatic variables were identified by using the partial least squares method. The common patterns of growth trends, pointer years, and mean sensitivities among sites provided evidences for the impact of environmental changes operating at a regional scale. The results of growth–climate analysis indicated that these changes were strongly influenced by the climatic conditions of the previous year. The climate sensitivity of beech increased progressively in response to more frequent and intense heat waves and warming-related droughts, especially during recent decades, leading to remarkable inter-site synchronization. The changes were much more pronounced for sites located in lowlands (<300 m). The differences in growth responses along the altitudinal gradient and the consequences of warming for beech growth and physiology are discussed. [less ▲]

Detailed reference viewed: 38 (12 ULg)
Full Text
Peer Reviewed
See detailReprésentations et expérience des pères « primipares » de l’allaitement maternel : lien avec la durée de l’allaitement
Noirhomme-Renard, Florence ULg; Michèle, Close; Gosset, Christiane ULg

in Journal de Pédiatrie et de Puériculture (2015), 28(1), 7-15

ntroduction. — This study aim to investigate fathers experiences and representations in regard to breastfeeding. Methods. — Two groups of fathers were recruited in the year following the birth of their ... [more ▼]

ntroduction. — This study aim to investigate fathers experiences and representations in regard to breastfeeding. Methods. — Two groups of fathers were recruited in the year following the birth of their child: a group whose child was breastfed less than three months (n = 16), and the other whose child was breastfed more than 6months (n=17). They were interviewed by semi-structured interviews and completed a questionnaire of attitudes toward child feeding (IIFAS). Results. — Although the representation that had fathers of breastfeeding during pregnancy dif- fered somewhat between the two groups, medical and social factors are primarily associated with a short AM: medical complications in the mother or the child, social vulnerabilities, early breastfeeding difficulties. The involvement of health professionals has been mentioned by many fathers when breastfeeding difficulties, but it has, in most cases, led to the failure of AM in time. Increased fathers take place in the triad, sometimes modulated by their partner, and their emo- tional involvement and practice in breastfeeding are associated with long AM. Fathers whose baby was breastfed for more than 6 months have a score more in favor of breastfeeding on the scale IIFAS. Conclusion. — The inclusion of fathers in the comprehensive model of the determinants of breastfeeding provides further insight to the factors already identified. [less ▲]

Detailed reference viewed: 37 (9 ULg)
Full Text
Peer Reviewed
See detailStochastic modelling of reservoir sedimentation in a semi-arid watershed
Adam, Nicolas; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Water Resources Management (2015), 29(3), 785-800

Sedimentation in large reservoirs is a major concern in semi-arid regions characterized by severe seasonal water scarcity. As a contribution to improved sediment management, this study analyses the real ... [more ▼]

Sedimentation in large reservoirs is a major concern in semi-arid regions characterized by severe seasonal water scarcity. As a contribution to improved sediment management, this study analyses the real case of the reservoir of Sidi Yacoub in the north of Algeria. First, a dynamic model of the reservoir was set up and used to estimate past water and sediment inflows (period 1990-2010) based on data recorded by the dam operator and measurements at a gauging station located downstream of the reservoir. Second, in a stochastic framework using the statistical characteristics of inflow and outflow discharges, a projection of future sedimentation was performed until 2030, assuming stationarity of the statistical distributions. Third, the model was used to investigate the influence of possible climate change and to quantify the positive effects of soil conservation measures upstream. [less ▲]

Detailed reference viewed: 73 (25 ULg)
Full Text
Peer Reviewed
See detailEffects of low dose endosulfan exposure on brain neurotransmitter levels in the African clawed frog Xenopus laevis
Preud'Homme, Valérie; Milla, Sylvain; Gillardin, Virginie et al

in Chemosphere (2015), 120(2), 357-364

Understanding the impact of pesticides in amphibians is of growing concern to assess the causes of their decline. Among pesticides, endosulfan belongs to one of the potential sources of danger because of ... [more ▼]

Understanding the impact of pesticides in amphibians is of growing concern to assess the causes of their decline. Among pesticides, endosulfan belongs to one of the potential sources of danger because of its wide use and known effects, particularly neurotoxic, on a variety of organisms. However, the effect of endosulfan was not yet evaluated on amphibians at levels encompassing simultaneously brain neurotransmitters and behavioural endpoints. In this context, tadpoles of the African clawed frog Xenopus laevis were submitted to four treatments during 27 d: one control, one ethanol control, and two low environmental concentrations of endosulfan (0.1 and 1 μg L−1). Endosulfan induced a significant increase of brain serotonin level at both concentrations and a significant increase of brain dopamine and GABA levels at the lower exposure but acetylcholinesterase activity was not modified by the treatment. The gene coding for the GABA transporter 1 was up-regulated in endosulfan contaminated tadpoles while the expression of other genes coding for the neurotransmitter receptors or for the enzymes involved in their metabolic pathways was not significantly modified by endosulfan exposure. Endosulfan also affected foraging, and locomotion in links with the results of the physiological assays, but no effects were seen on growth. These results show that low environmental concentrations of endosulfan can induce adverse responses in X. laevis tadpoles. At a broader perspective, this suggests that more research using and linking multiple markers should be used to understand the complex mode of action of pollutants. [less ▲]

Detailed reference viewed: 90 (30 ULg)
Full Text
Peer Reviewed
See detailSignes et jouabilité : l’interface comme outil de ludicisation
Barnabé, Fanny ULg

in Interfaces Numériques (2015), 4(1),

As shown by the recent works on the subject (Rao, 2008 ; Simonnot, 2008 ; all papers presented at the symposium Game and playability in the digital age), researchers now seem to agree on the fact that the ... [more ▼]

As shown by the recent works on the subject (Rao, 2008 ; Simonnot, 2008 ; all papers presented at the symposium Game and playability in the digital age), researchers now seem to agree on the fact that the digital has an intrinsic playability (it is “ludogenic” according to Vial, 2012) and that this property is not uninvolved with the current spread of the “gamification” or “ludification” (Genvo, 2011) phenomenons. Following these considerations, this paper aims to examine a specific angle of this privileged relationship between digital and game, namely the fundamental role played by the interfaces (both graphical and physical). We will try to demonstrate through various examples the deeply playable nature (I.e suitable to set off a playful attitude) of the different kinds of interface, but also to examine its causes: is there a structural basis that could explain this affinity with the play? With this aim in mind, theories of game (playful attitude) will be intersected with interface theories in order to demonstrate the existence of many similarities. The hypothesis that guides this work is that this transitional device’s playability owes more to its semiotic nature than to its belonging to digital. Indeed, as a system of signs, the interface has two characteristics that make it fit to generate a playful attitude in the user: the metaphoric distance and the increase of possible actions. [less ▲]

Detailed reference viewed: 19 (1 ULg)
Full Text
Peer Reviewed
See detailAnalysis versus synthesis for trending gas-path measurement time series
Borguet, Sébastien ULg; Léonard, Olivier ULg; Dewallef, Pierre ULg

in Journal of Engineering for Gas Turbines & Power (2015), 137

Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear ... [more ▼]

Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear filters such as the EWMA filter are traditionally used for noise removal. Unfortunately, these low-pass filters distort trend shifts indicative of faults, which increases the detection delay. The present paper investigates two new approaches to nonlinear filtering of time series. On the one hand, the synthesis approach reconstructs the signal as a combination of elementary signals chosen from a predefined library. On the other hand, the analysis approach imposes a constraint on the shape of the signal (e.g., piecewise constant). Both approaches incorporate prior information about the signal in a different way, but they lead to trend filters that are very capable at noise removal while preserving at the same time sharp edges in the signal. This is highlighted through the comparison with a classical linear filter on a batch of synthetic data representative of typical engine fault profiles. [less ▲]

Detailed reference viewed: 22 (0 ULg)