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See detailExperimental validation of a thermal model of a LOx flooded ball bearing
Servais, Christophe ULg; Bozet, Jean-Luc ULg; Kreit, Patrick ULg et al

in Tribology International (2014), 80

Ball bearings of turbopumps of rocket engines work in very singular conditions; they are flooded into liquid oxygen or liquid hydrogen. Therefore, the use of any conventional lubricants (oil or grease) is ... [more ▼]

Ball bearings of turbopumps of rocket engines work in very singular conditions; they are flooded into liquid oxygen or liquid hydrogen. Therefore, the use of any conventional lubricants (oil or grease) is prescribed. Although cryogenic fluids can cool this kind of ball bearing, they cannot separate the surfaces in contact. As a result, there is a significant increase in frictional power losses. This paper presents tests performed on a cryotechnic ball bearing flooded in liquid oxygen. The test results showed that beyond a critical loading of the bearing, a sudden increase in temperature occurred. A thermal model is also put forward, in order to understand and anticipate especially the thermal instability described above. [less ▲]

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See detailToward a tool aimed to quantify soil compaction risks at a regional scale: application to Wallonia (Belgium)
D'Or, Dimitri; Destain, Marie-France ULg

in Soil & Tillage Research (2014), 144

The spatial analysis of the soil compaction risk has been developed at the regional level and applied to Wallonia (Belgium). The methodology is based on the estimation of the probability of exceeding the ... [more ▼]

The spatial analysis of the soil compaction risk has been developed at the regional level and applied to Wallonia (Belgium). The methodology is based on the estimation of the probability of exceeding the preconsolidation stress due to the application of loads on the soil. Preconsolidation stresses (Pc) are computed from the pedotransfer functions of Horn and Fleige (2003) at pF 1.8 and 2.5 and classified into 6 categories ranging from very low Pc (< 30 kPa) to extremely high Pc (> 150 kPa). The computation requires the knowledge of pedological (texture, organic content), mechanical (bulk density, cohesion, internal friction angle), and hydraulic variables (water content available, non-available water content, air capacity, saturated hydraulic conductivity). These variables are obtained from databases like HYPRES or AARDEWERK or from pedotransfer functions. The computation of Pc takes into account the spatial structure of the data: in some cases, data are abundant (e.g. texture data) and spatial variability is taken into account through geostatistical methods. In other cases, the data is sparse but uncertainty information can be extracted from the knowledge of the statistical distribution. Maps of the most probable Pc class are produced. Uncertainty is computed as the classification error probability. Implementation of these methods in Wallonia showed that Pc values higher than 120 kPa are reached either on 64 % of the territory at pF 2.5 or on 55 % at pF 1.8. A higher uncertainty was found at pF 2.5 than at pF 1.8. Uncertainty was also found higher for clay and clayed loess than for other textural classes present in Wallonia. The risk of compaction is defined as the probability that Pc is exceeded by the stress created by a load applied to the soil at a depth of 40 cm, the loads being similar to those induced by agricultural or forestry tires. It appeared that subsoil compaction risks exist mainly in loamy forest soils with small coarse fragments supporting loads similar to that existing on logging machines. In the zones where the uncertainty is low, the developed tool could be used as a basis for providing policy measures in order to promote soil-friendly farming and forest practices. [less ▲]

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See detailComment je traite … Recommandations pour interrompre un traitement médicamenteux
SCHEEN, André ULg

in Revue Médicale de Liège (2014), 69(12), 644-649

L’interruption d’un traitement pharmacologique est une situation clinique fréquente qui peut paraître plus simple à gérer que l’instauration d’un nouveau traitement, mais qui impose néanmoins de remplir ... [more ▼]

L’interruption d’un traitement pharmacologique est une situation clinique fréquente qui peut paraître plus simple à gérer que l’instauration d’un nouveau traitement, mais qui impose néanmoins de remplir certaines conditions et de respecter certaines précautions : 1) pouvoir expliciter les raisons qui justifient l’arrêt du traitement; 2) vérifier qu’il n’y a pas de danger à interrompre le traitement (même si cette interruption est transitoire); 3) savoir comment gérer au mieux l’arrêt de la thérapeutique, en particulier choisir entre une interruption immédiate et une décroissance posologique progressive; et, enfin, 4) assurer un suivi approprié du patient dûment informé chez lequel le traitement vient d’être stoppé. [less ▲]

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See detailExiste-t-il des phénomènes mentaux?
Dewalque, Arnaud ULg; Seron, Denis ULg

in Philosophie (2014), 124

This paper offers a critical discussion of the so-called argument from the transparency of experience. We recall of the argument against the historical background of phenomenal anti-dualism (Natorp, Wundt ... [more ▼]

This paper offers a critical discussion of the so-called argument from the transparency of experience. We recall of the argument against the historical background of phenomenal anti-dualism (Natorp, Wundt, Russell) and identify three difficulties of it. Eventually, we propose an alternative view, which we call phenomenological dualism. On the proposed view, there is a sense in which our mental states may be said to appear to us, hence there is a sense to say that there are mental phenomena. [less ▲]

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See detailCracs, Neets... and Agency, le vocabulaire d’un autre monde... ou pas?
Vandoorne, Chantal ULg

in Education Santé (2014), (306), 7-8

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See detailCalcifications des tissus mous des jambes
COLLIN, Romain ULg; ANDRE, Béatrice ULg; Crielaard, Jean-Michel ULg et al

in Revue Médicale de Liège (2014), 69(12), 641-643

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See detailAdolescent Risk Behaviours and Protective Factors Against Peer Influence
Cattelino, Elena; Glowacz, Fabienne ULg; Born, Michel ULg et al

in Journal of Adolescence (2014), 37(8), 1353-1362

This study examined the relationships between protective factors and involvement in risk behaviour of Italian adolescents with friends involved in risk. Protective factors were drawn from models of peers ... [more ▼]

This study examined the relationships between protective factors and involvement in risk behaviour of Italian adolescents with friends involved in risk. Protective factors were drawn from models of peers and from individual skills (perceived regulatory self-efficacy, intolerant attitudes about deviance) and orientation (to health, school, religion). The data are from two waves, 1 year apart, of a questionnaire survey of adolescents in northwestern Italy. Participants were 908 adolescents (42% boys) ages 14–16 years. Results of a hierarchical regression revealed that religiosity is a protective factor and that friends’ models for conventional behaviours and positive attitude about health can mitigate the influence of deviant friends on adolescent risk behaviour 1 year later, even after controlling for prior levels of risk behaviour. Possible implications of this study suggest the importance of implementing preventive interventions by involving the peer group, especially at about 16 years, and working with heterogeneous (deviant and nondeviant) groups. [less ▲]

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See detailToward a tool aimed to quantify soil compaction risks at a regional scale: application to Wallonia (Belgium)
D'Or, Dimitri; Destain, Marie-France ULg

in Soil & Tillage Research (2014), 144

The spatial analysis of the soil compaction risk has been developed at the regional level and applied to Wallonia (Belgium). The methodology is based on the estimation of the probability of exceeding the ... [more ▼]

The spatial analysis of the soil compaction risk has been developed at the regional level and applied to Wallonia (Belgium). The methodology is based on the estimation of the probability of exceeding the preconsolidation stress due to the application of loads on the soil. Preconsolidation stresses (Pc) are computed from the pedotransfer functions of Horn and Fleige (2003) at pF 1.8 and 2.5 and classified into 6 categories ranging from very low Pc (< 30 kPa) to extremely high Pc (> 150 kPa). The computation requires the knowledge of pedological (texture, organic content), mechanical (bulk density, cohesion, internal friction angle), and hydraulic variables (water content available, non-available water content, air capacity, saturated hydraulic conductivity). These variables are obtained from databases like HYPRES or AARDEWERK or from pedotransfer functions. The computation of Pc takes into account the spatial structure of the data: in some cases, data are abundant (e.g. texture data) and spatial variability is taken into account through geostatistical methods. In other cases, the data is sparse but uncertainty information can be extracted from the knowledge of the statistical distribution. Maps of the most probable Pc class are produced. Uncertainty is computed as the classification error probability. Implementation of these methods in Wallonia showed that Pc values higher than 120 kPa are reached either on 64 % of the territory at pF 2.5 or on 55 % at pF 1.8. A higher uncertainty was found at pF 2.5 than at pF 1.8. Uncertainty was also found higher for clay and clayed loess than for other textural classes present in Wallonia. The risk of compaction is defined as the probability that Pc is exceeded by the stress created by a load applied to the soil at a depth of 40 cm, the loads being similar to those induced by agricultural or forestry tires. It appeared that subsoil compaction risks exist mainly in loamy forest soils with small coarse fragments supporting loads similar to that existing on logging machines. In the zones where the uncertainty is low, the developed tool could be used as a basis for providing policy measures in order to promote soil-friendly farming and forest practices. [less ▲]

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See detailSur les définitions de Dieu. Entretien avec Valère Novarina
Dubouclez, Olivier ULg; Novarina, Valère

in Littérature (2014)

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See detailToward a tool aimed to quantify soil compaction risks at a regional scale: application to Wallonia (Belgium)
D'Or, Dimitri; Destain, Marie-France ULg

in Soil & Tillage Research (2014), 144

The spatial analysis of the soil compaction risk has been developed at the regional level and applied to Wallonia (Belgium). The methodology is based on the estimation of the probability of exceeding the ... [more ▼]

The spatial analysis of the soil compaction risk has been developed at the regional level and applied to Wallonia (Belgium). The methodology is based on the estimation of the probability of exceeding the preconsolidation stress due to the application of loads on the soil. Preconsolidation stresses (Pc) are computed from the pedotransfer functions of Horn and Fleige (2003) at pF 1.8 and 2.5 and classified into 6 categories ranging from very low Pc (< 30 kPa) to extremely high Pc (> 150 kPa). The computation requires the knowledge of pedological (texture, organic content), mechanical (bulk density, cohesion, internal friction angle), and hydraulic variables (water content available, non-available water content, air capacity, saturated hydraulic conductivity). These variables are obtained from databases like HYPRES or AARDEWERK or from pedotransfer functions. The computation of Pc takes into account the spatial structure of the data: in some cases, data are abundant (e.g. texture data) and spatial variability is taken into account through geostatistical methods. In other cases, the data is sparse but uncertainty information can be extracted from the knowledge of the statistical distribution. Maps of the most probable Pc class are produced. Uncertainty is computed as the classification error probability. Implementation of these methods in Wallonia showed that Pc values higher than 120 kPa are reached either on 64 % of the territory at pF 2.5 or on 55 % at pF 1.8. A higher uncertainty was found at pF 2.5 than at pF 1.8. Uncertainty was also found higher for clay and clayed loess than for other textural classes present in Wallonia. The risk of compaction is defined as the probability that Pc is exceeded by the stress created by a load applied to the soil at a depth of 40 cm, the loads being similar to those induced by agricultural or forestry tires. It appeared that subsoil compaction risks exist mainly in loamy forest soils with small coarse fragments supporting loads similar to that existing on logging machines. In the zones where the uncertainty is low, the developed tool could be used as a basis for providing policy measures in order to promote soil-friendly farming and forest practices. [less ▲]

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See detailTheoretical power spectra of mixed modes in low-mass red giant stars
Grosjean, Mathieu ULg; Dupret, Marc-Antoine ULg; Belkacem, Kevin et al

in Astronomy and Astrophysics (2014), 572

CoRoT and Kepler observations of red giant stars revealed very rich spectra of non-radial solar-like oscillations. Of particular interest was the detection of mixed modes that exhibit significant ... [more ▼]

CoRoT and Kepler observations of red giant stars revealed very rich spectra of non-radial solar-like oscillations. Of particular interest was the detection of mixed modes that exhibit significant amplitude, both in the core and at the surface of the stars. It opens the possibility of probing the internal structure from their innermost layers up to their surface throughout their evolution on the red giant branch, as well as on the red clump. Our objective is primarily to provide physical insight into the mechanism responsible for mixed-mode amplitudes and lifetimes. Subsequently, we aim at understanding the evolution and structure of red-giant spectra along with their evolution. The study of energetic aspects of these oscillations is also important for predicting the mode parameters in the power spectrum. Non-adiabatic computations, including a time-dependent treatment of convection, are performed and provide the lifetimes of radial and non-radial mixed modes. We then combine these mode lifetimes and inertias with a stochastic excitation model that gives us their heights in the power spectra. For stars representative of CoRoT and Kepler observations, we show under which circumstances mixed modes have heights comparable to radial ones. We stress the importance of the radiative damping in determining the height of mixed modes. Finally, we derive an estimate for the height ratio between a g-type and a p-type mode. This can thus be used as a first estimate of the detectability of mixed modes. [less ▲]

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See detailA New Shift-Share Method
Artige, Lionel ULg; Van Neuss, Leif ULg

in Growth and Change (2014), 45(4), 667-683

Shift-share analysis is a decomposition technique widely used in regional studies to quantify an industry-mix effect and a competitive effect on the growth of regional employment (or any other relevant ... [more ▼]

Shift-share analysis is a decomposition technique widely used in regional studies to quantify an industry-mix effect and a competitive effect on the growth of regional employment (or any other relevant variable) relative to the national average. This technique has always been subject to criticism for its lack of theoretical basis. This paper presents a critical assessment of the methods suggested by Dunn (1960) and by Esteban-Marquillas (1972) and proposes a new shift-share method, which separates out the two effects unambiguously. By way of illustration, we provide an application to manufacturing employment in the Belgian provinces between 1995 and 2007. [less ▲]

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See detailLe médicament du mois Canagliflozine (Invokana®) : inhibiteur des cotransporteurs rénaux sglt2 pour traiter le diabète de type 2
SCHEEN, André ULg

in Revue Médicale de Liège (2014), 69(12), 692-699

Canagliflozin is an inhibitor of sodium-glucose cotransporters type 2 (SGLT2) that are present in renal tubules. This specific insulin-independent mechanism promotes glucosuria, which results in a ... [more ▼]

Canagliflozin is an inhibitor of sodium-glucose cotransporters type 2 (SGLT2) that are present in renal tubules. This specific insulin-independent mechanism promotes glucosuria, which results in a reduction in fasting and postprandial glycaemia and a decrease of glycated haemoglobin (HbA1c). Furthermore, canagliflozin promotes weight loss and lowers arterial (mainly systolic) blood pressure. Its efficacy is decreased in patients with renal insufficiency and the treatment should be stopped if estimated glomerular filtration rate is below 45 ml/min/1.73 m². Both the efficacy and safety of canagliflozin have been investigated in 24 to 104-week controlled trials versus placebo or versus an active comparator (glimepiride or sitagliptin). The mean reduction in HbA1c averages 0.75% when added to other treatments, as compared to placebo. The 100 mg dose is as active as sitagliptin 100 mg while the 300 mg canagliflozin dose is even more efficacious. Adverse events are mostly mycotic genital infections and more rarely mild urinary tract infections. Caution is required in elderly patients and the risk of volume depletion should be checked (hypotension). Hypoglycaemia may occur only in patients already treated with an insulin-secreting agent or insulin. Canagliflozin is commercialized under the trade name Invokana®, at the doses of 100 mg and 300 mg once daily, for the treatment of type 2 diabetes. [less ▲]

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See detailManifesto de Curitiba: pela Prevenção Quaternária e por uma Medicina sem conflitos de interesse
Silva, André Luiz da; Mangin, Derelie; Pizzanelli, Miguel et al

in Revista Brasileira de Medicina de Família e Comunidade (2014), 9(33), 371-374

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See detailDe beklemtoning van samenstellingen in de tussentaal van Franstalige leerders van het Nederlands uit het immersie- en niet-immersieonderwijs
Bui-Anh, Vu ULg; Jouniaux, Anthony; Hiligsmann, Philippe et al

in n/f (2014), 12

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See detailThe Growth of the Skull Roof Plates in Arabosteus variabilis (Acanthothoraci, Placodermi) from the Early Devonian Jauf Formation (Saudi Arabia): Preliminary Results
Olive, Sébastien ULg; Goujet, Daniel; Lelièvre, Hervé et al

in Paleontological Journal (2014), 48(9), 992-1002

The skull roof growth of Arabosteus variabilis (Acanthothoraci), from the Pragian-Early Emsian of Saudi Arabia is studied on the basis of well preserved growth lines on the dermal plates. A clear tendency ... [more ▼]

The skull roof growth of Arabosteus variabilis (Acanthothoraci), from the Pragian-Early Emsian of Saudi Arabia is studied on the basis of well preserved growth lines on the dermal plates. A clear tendency towards growth in length, i.e. allometry in length, can be observed for all studied skull roof plates of Arabosteus variabilis as well as for the skull roof in general. Each studied plate displays particular growth shaping the skull roof according to its position in the skull roof pattern, e.g., the preorbital plate controls the shape of the part of the orbit and the nuchal plate retains the relative proportions in the skull roof during growth. [less ▲]

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See detailGenetic parameters for direct and maternal calving ease in Walloon dairy cattle based on linear and threshold models
Vanderick, Sylvie ULg; Troch, Thibault ULg; Gillon, Alain et al

in Journal of Animal Breeding & Genetics (2014), 131(6), 513-521

Calving ease scores from Holstein dairy cattle in the Walloon Region of Belgium were analysed using univariate linear and threshold animal models. Variance components and derived genetic parameters were ... [more ▼]

Calving ease scores from Holstein dairy cattle in the Walloon Region of Belgium were analysed using univariate linear and threshold animal models. Variance components and derived genetic parameters were estimated from a dataset including 33,155 calving records. Included in the models were season, herd and sex of calf age of dam classes group of calvings interaction as fixed effects, herd year of calving, maternal permanent environment and animal direct and maternal additive genetic as random effects. Models were fitted with the genetic correlation between direct and maternal additive genetic effects either estimated or constrained to zero. Direct heritability for calving ease was about 8% with linear models and about 12% with threshold models. Maternal heritabilities were about 2% and 4%, respectively. Genetic correlation between direct and maternal additive effects was found to be not significantly different from zero. Models were compared in terms of goodness of fit and predictive ability. Criteria of comparison such as mean squared error, correlation between observed and predicted calving ease scores as well as between estimated breeding values were estimated from 85,118 calving records. The results provided few differences between linear and threshold models even though correlations between estimated breeding values from subsets of data for sires with progeny from linear model were 17% and 23 % greater for direct and maternal genetic effects, respectively, than from threshold model. For the purpose of genetic evaluation for calving ease in Walloon Holstein dairy cattle, the linear animal model without covariance between direct and maternal additive effects was found to be the best choice. [less ▲]

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See detailConfiance politique et institutions internationales. Les perceptions de l'efficacité, de la légitimité et de la démocratie par des jeunes
Grandjean, Geoffrey ULg

in Revue de la Faculté de Droit de l'Université de Liège (2014), 3

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See detailPhysical and bacterial controls on inorganic nutrients and dissolved organic carbon during a sea ice growth and decay experiment
Zhou, Jiayun ULg; Delille, Bruno ULg; Kaartokallio, Hermanni et al

in Marine Chemistry (2014), 166

We investigated how physical incorporation, brine dynamics and bacterial activity regulate the distribution of inorganic nutrients and dissolved organic carbon (DOC) in artificial sea ice during a 19-day ... [more ▼]

We investigated how physical incorporation, brine dynamics and bacterial activity regulate the distribution of inorganic nutrients and dissolved organic carbon (DOC) in artificial sea ice during a 19-day experiment that included periods of both ice growth and decay. The experiment was performed using two series of mesocosms: the first consisted of seawater and the second consisted of seawater enriched with humic-rich river water. We grew ice by freezing the water at an air temperature of -14 °C for 14 days after which ice decay was induced by increasing the air temperature to -1 °C. Using the ice temperatures and bulk ice salinities, we derived the brine volume fractions, brine salinities and Rayleigh numbers. The temporal evolution of these physical parameters indicate that there was a succession of 3 stages in the brine dynamics: forced-convection, followed by bottom convection during ice growth, and then brine stratification during ice decay. The major findings are: (1) the incorporation of dissolved compounds (nitrate, nitrite, ammonium, phosphate, silicate, and DOC) into the sea ice was not conservative (relative to salinity) during ice growth. Brine convection clearly influenced the incorporation of the dissolved compounds, since the non-conservative behavior of the dissolved compounds was particularly pronounced in the absence of brine convection. (2) Bacterial activity further regulated nutrient availability in the ice: ammonium and nitrite accumulated as a result of remineralization processes, although bacterial production was too low to induce major changes in DOC concentrations. (3) Different forms of DOC have different properties and hence incorporation efficiencies. In particular, the terrestrially-derived DOC from the river water was less efficiently incorporated into sea ice than the DOC in the seawater. Therefore the main factors regulating the distribution of the dissolved compounds within sea ice are clearly a complex interaction of brine dynamics, biological activity and in the case of dissolved organic matter, the physico-chemical properties of the dissolved constituents themselves. [less ▲]

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See detailDouble thermoresponsive di- and triblock copolymers based on N-vinylcaprolactam and N-vinylpyrrolidone: synthesis and comparative study of solution behaviour
Kermagoret, Anthony ULg; Mathieu, Kevin ULg; Thomassin, Jean-Michel ULg et al

in Polymer Chemistry (2014), 5(22), 6534-6544

Poly(N-vinylcaprolactam) (PNVCL) and poly(N-vinylpyrrolidone) (PNVP) are water soluble polymers of interest especially in the biomedical field. Moreover, PNVCL is characterized by a lower critical ... [more ▼]

Poly(N-vinylcaprolactam) (PNVCL) and poly(N-vinylpyrrolidone) (PNVP) are water soluble polymers of interest especially in the biomedical field. Moreover, PNVCL is characterized by a lower critical solution temperature close to 36 °C in water, which makes it useful for the design of thermoresponsive systems. In this context, we used the cobalt-mediated radical polymerization (CMRP) and reaction coupling (CMRC) for synthesizing a series of well-defined NVCL and NVP-based copolymers, including statistical copolymers as well as double thermoresponsive diblocks and triblocks. Dynamic light scattering and turbidimetry analyses highlighted the crucial impact of the copolymer composition and architecture on the cloud point temperature (TCP) of each segment and also their influence on the multistep assembly behaviour of block copolymers. Addition of NaCl enabled us to adjust the inter-TCP range of the di- and triblock in which selective precipitation of one block and self-assembly of the copolymer were favoured. Overall, data presented here provide a basis for the synthesis of a broad range of NVCL/NVP based copolymer architectures with a tunable thermal response in water. [less ▲]

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See detailLong-term evolution and seasonal modulation of methanol above Jungfraujoch (46.5°N, 8.0°E): Optimisation of the retrieval strategy, comparison with model and independant observations
Bader, Whitney ULg; Stavrakou, T; Muller, J-F et al

in Atmospheric Measurement Techniques (2014), 7

Methanol (CH3OH) is the second most abundant organic compound in the Earth's atmosphere after methane. In this work, we present the first long-term time series of methanol total, lower tropospheric and ... [more ▼]

Methanol (CH3OH) is the second most abundant organic compound in the Earth's atmosphere after methane. In this work, we present the first long-term time series of methanol total, lower tropospheric and upper tropospheric-lower stratospheric partial columns derived from the analysis of high resolution Fourier transform infrared solar spectra recorded at the Jungfraujoch station (46.5° N, 3580 m a.s.l.). The retrieval of methanol is very challenging due to strong absorptions of ozone in the region of the selected υ8 band of CH3OH. Two wide spectral intervals have been defined and adjusted in order to maximize the information content. Methanol does not exhibit a significant trend over the 1995–2012 time period, but a strong seasonal modulation characterized by maximum values and variability in June–July, minimum columns in winter and a peak-to-peak amplitude of 130%. In situ measurements performed at the Jungfraujoch and ACE-FTS occultations give similar results for the methanol seasonal variation. The total and lower tropospheric columns are also compared with IMAGESv2 model simulations. There is no systematic bias between the observations and IMAGESv2 but the model underestimates the peak-to-peak amplitude of the seasonal modulations. [less ▲]

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See detailSurvey of Artificial Insemination Practices in Algeria
Souames, Samir; Hanzen, Christian ULg; Detilleux, Johann ULg et al

in Research Journal for Veterinary Practitioner (2014), 3(1), 1-9

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See detailRecent Northern Hemisphere stratospheric HCl increase due to atmospheric circulation changes
Mahieu, Emmanuel ULg; Chipperfield, M. P.; Notholt, J. et al

in Nature (2014), 515(7525), 104--107

The abundance of chlorine in the Earth’s atmosphere increased considerably during the 1970s to 1990s, following large emissions of anthropogenic long-lived chlorine-containing source gases, notably the ... [more ▼]

The abundance of chlorine in the Earth’s atmosphere increased considerably during the 1970s to 1990s, following large emissions of anthropogenic long-lived chlorine-containing source gases, notably the chlorofluorocarbons. The chemical inertness of chlorofluorocarbons allows their transport and mixing throughout the troposphere on a global scale[1], before they reach the stratosphere where they release chlorine atoms that cause ozone depletion[2]. The large ozone loss over Antarctica[3] was the key observation that stimulated the definition and signing in 1987 of the Montreal Protocol, an international treaty establishing a schedule to reduce the production of the major chlorine- and bromine-containing halocarbons. Owing to its implementation, the near-surface total chlorine concentration showed a maximum in 1993, followed by a decrease of half a per cent to one per cent per year[4], in line with expectations. Remote-sensing data have revealed a peak in stratospheric chlorine after 1996[5], then a decrease of close to one per cent per year[6,7], in agreement with the surface observations of the chlorine source gases and model calculations[7]. Here we present ground-based and satellite data that show a recent and significant increase, at the 2σ level, in hydrogen chloride (HCl), the main stratospheric chlorine reservoir, starting around 2007 in the lower stratosphere of the Northern Hemisphere, in contrast with the ongoing monotonic decrease of near-surface source gases. Using model simulations, we attribute this trend anomaly to a slowdown in the Northern Hemisphere atmospheric circulation, occurring over several consecutive years, transporting more aged air to the lower stratosphere, and characterized by a larger relative conversion of source gases to HCl. This short-term dynamical variability will also affect other stratospheric tracers and needs to be accounted for when studying the evolution of the stratospheric ozone layer. [less ▲]

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See detailThe Robust Economic Statistical Design of the Hotelling’s T^2 Chart
Faraz, Alireza ULg; Chalaki, Kamyar; Saniga, Erwin et al

in Communications in Statistics : Theory & Methods (2014)

Economic statistical designs aim at minimizing the cost of process monitoring when a specific scenario or a set of estimated process and cost parameters is given. However, in practical situations the ... [more ▼]

Economic statistical designs aim at minimizing the cost of process monitoring when a specific scenario or a set of estimated process and cost parameters is given. However, in practical situations the process may be affected by more than one scenario which may lead to severe cost penalties for upsetting the true scenario. This paper presents the robust economic statistical design (RESD) of the T^2 chart to reduce the monetary losses when there are multiple distinct scenarios. The genetic algorithm optimization method is employed here to minimize the total expected monitoring cost across all distinct scenarios. Through two numerical examples the proposed method is illustrated. Simulation studies indicate that the robust economic statistical designs should be encouraged in practice. [less ▲]

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See detailSouthern Massive Stars at High Angular Resolution: Observational Campaign and Companion Detection
Sana, H.; Le Bouquin, J.-B.; Lacour, S. et al

in Astrophysical Journal Supplement Series (2014), 215

Multiplicity is one of the most fundamental observable properties of massive O-type stars and offers a promising way to discriminate between massive star formation theories. Nevertheless, companions at ... [more ▼]

Multiplicity is one of the most fundamental observable properties of massive O-type stars and offers a promising way to discriminate between massive star formation theories. Nevertheless, companions at separations between 1 and 100 milliarcsec (mas) remain mostly unknown due to intrinsic observational limitations. At a typical distance of 2 kpc, this corresponds to projected ph [less ▲]

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See detailOrigin and immunoescape of uterine cervical cancer
Van hede, Dorien ULg; Langers, Inge ULg; DELVENNE, Philippe ULg et al

in Presse Médicale (2014)

Human papillomavirus associated uterine cervical cancer is an important public health problem since it is classified as the fourth most common cancer in women worldwide with more than 500 000 recorded ... [more ▼]

Human papillomavirus associated uterine cervical cancer is an important public health problem since it is classified as the fourth most common cancer in women worldwide with more than 500 000 recorded cases. This review is focused on where and why HPV infection induces cervical cancers and how this virus avoids the host immune response. Immunological therapeutic approaches are also addressed. [less ▲]

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See detailSearching for faint companions with VLTI/PIONIER. II. 92 main sequence stars from the Exozodi survey
Marion, Lindsay ULg; Absil, Olivier ULg; Ertel, S. et al

in Astronomy and Astrophysics (2014), 570

Context. The Exozodi survey aims to determine the occurrence rate of bright exozodiacal discs around nearby main sequence stars using infrared interferometry. Although the Exozodi survey targets have been ... [more ▼]

Context. The Exozodi survey aims to determine the occurrence rate of bright exozodiacal discs around nearby main sequence stars using infrared interferometry. Although the Exozodi survey targets have been carefully selected to avoid the presence of binary stars, the results of this survey can still be biased by the presence of unidentified stellar companions. <BR /> Aims: Using the PIONIER data set collected within the Exozodi survey in 2012, we aim to search for the signature of point-like companions around the Exozodi target stars. <BR /> Methods: We make use of both the closure phases and squared visibilities collected by PIONIER to search for companions within the ~100 mas interferometric field of view. The presence of a companion is assessed by computing the goodness of fit to the data for a series of binary models with various separations and contrasts. <BR /> Results: Five stellar companions are resolved for the first time around five A-type stars: HD 4150, HD 16555, HD 29388, HD 202730, and HD 224392 (although the companion to HD 16555 was independently resolved by speckle interferometry while we were carrying out the survey). In the most likely case of main sequence companions, their spectral types range from A5V to K4V. Three of these stars were already suspected to be binaries from Hipparcos astrometric measurements, although no information was available on the companions themselves so far. In addition to debiasing the statistics of the Exozodi survey, these results can also be used to revise the fraction of visual binaries among A-type stars, suggesting that an extra ~13% A-type stars are visual binaries in addition to the ones detected in previous direct imaging surveys. <BR /> Conclusions: We estimate that about half the population of nearby A-type stars could be resolved as visual binaries using a combination of state-of-the-art interferometry and single-aperture imaging, and we suggest that a significant fraction of these binaries remains undetected to date. [less ▲]

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See detailA near-infrared interferometric survey of debris-disk stars. IV. An unbiased sample of 92 southern stars observed in H band with VLTI/PIONIER
Ertel, S.; Absil, Olivier ULg; Defrere, D. et al

in Astronomy and Astrophysics (2014), 570

Context. Detecting and characterizing circumstellar dust is a way to study the architecture and evolution of planetary systems. Cold dust in debris disks only traces the outer regions. Warm and hot ... [more ▼]

Context. Detecting and characterizing circumstellar dust is a way to study the architecture and evolution of planetary systems. Cold dust in debris disks only traces the outer regions. Warm and hot exozodiacal dust needs to be studied in order to trace regions close to the habitable zone. <BR /> Aims: We aim to determine the prevalence and to constrain the properties of hot exozodiacal dust around nearby main-sequence stars. <BR /> Methods: We searched a magnitude-limited (H <= 5) sample of 92 stars for bright exozodiacal dust using our VLTI visitor instrument PIONIER in the H band. We derived statistics of the detection rate with respect to parameters, such as the stellar spectral type and age or the presence of a debris disk in the outer regions of the systems. We derived more robust statistics by combining our sample with the results from our CHARA/FLUOR survey in the K band. In addition, our spectrally dispersed data allowed us to put constraints on the emission mechanism and the dust properties in the detected systems. <BR /> Results: We find an overall detection rate of bright exozodiacal dust in the H band of 11% (9 out of 85 targets) and three tentative detections. The detection rate decreases from early type to late type stars and increases with the age of the host star. We do not confirm the tentative correlation between the presence of cold and hot dust found in our earlier analysis of the FLUOR sample alone. Our spectrally dispersed data suggest that either the dust is extremely hot or the emission is dominated by the scattered light in most cases. The implications of our results for the target selection of future terrestrial planet-finding missions using direct imaging are discussed. [less ▲]

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See detailOccurence of Satellite RNAs associated with Cucumber mosaic virus isolated from banana (Musa sp.) in Ivory Coast
Kouadio, Kouakou Théodore; De Clerck, Caroline ULg; Agneroh, TA et al

in British Society for Plant Pathology - New Disease Reports (2014), 30

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See detailEconomic Statistical Design of the VP( X) ̅ Control Charts for Monitoring a Process under Non-normality
Seif, Asghar; Faraz, Alireza ULg; Saniga, Erwin

in International Journal of Operational Research (2014)

Recent studies proved that variable parameters (VP) X ̅ control charts not only detects process mean shifts quicker than the classical X ̅ control chart but also has better economic properties ... [more ▼]

Recent studies proved that variable parameters (VP) X ̅ control charts not only detects process mean shifts quicker than the classical X ̅ control chart but also has better economic properties. Furthermore, like most papers in control chart design, the fundamental assumption is that process data are normally distributed. Nevertheless, process quality variables may not be normal in application. In this paper, we investigate the economic statistical design of the VP X ̅ control chart when the underlying process distribution is non-normal. We illustrate the design procedure and perform a sensitivity analysis on the process and cost parameters based upon the degrees of skewness and kurtosis of the population using an industrial application. [less ▲]

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See detailBuilding galaxies, stars, planets and the ingredients for life between the stars. The science behind the European Ultraviolet-Visible Observatory
Gómez de Castro, Ana I.; Appourchaux, Thierry; Barstow, Martin A. et al

in Astrophysics and Space Science (2014), 354

This contribution gathers the contents of the white paper submitted by the UV community to the Call issued by the European Space Agency in March 2013, for the definition of the L2 and L3 missions in the ... [more ▼]

This contribution gathers the contents of the white paper submitted by the UV community to the Call issued by the European Space Agency in March 2013, for the definition of the L2 and L3 missions in the ESA science program. We outlined the key science that a large UV facility would make possible and the instrumentation to be implemented. The growth of luminous structures and the building blocks of life in the Universe began as primordial gas was processed in stars and mixed at galactic scales. The mechanisms responsible for this development are not well-understood and have changed over the intervening 13 billion years. To follow the evolution of matter over cosmic time, it is necessary to study the strongest (resonance) transitions of the most abundant species in the Universe. Most of them are in the ultraviolet (UV; 950 Å-3000 Å) spectral range that is unobservable from the ground. A versatile space observatory with UV sensitivity a factor of 50-100 greater than existing facilities will revolutionize our understanding of the Universe. Habitable planets grow in protostellar discs under ultraviolet irradiation, a by-product of the star-disk interaction that drives the physical and chemical evolution of discs and young planetary systems. The electronic transitions of the most abundant molecules are pumped by this UV field, providing unique diagnostics of the planet-forming environment that cannot be accessed from the ground. Earth's atmosphere is in constant interaction with the interplanetary medium and the solar UV radiation field. A 50-100 times improvement in sensitivity would enable the observation of the key atmospheric ingredients of Earth-like exoplanets (carbon, oxygen, ozone), provide crucial input for models of biologically active worlds outside the solar system, and provide the phenomenological baseline to understand the Earth atmosphere in context. [less ▲]

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See detailLe langage et l’homme
Dubuisson, Francois ULg

in Bulletin d'Analyse Phénoménologique [En ligne] (2014), 10(11),

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See detailTwo new aromadendrane sesquiterpenes from the stem bark of Alafia multiflora
Tchinda Tiabou, Alembert ULg; Tsala, David E.; Nnanga, Nga et al

in Natural Products Communications (2014), 9

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See detailLes progrès de la poésie en 1867. Portrait de Gautier en grand rapporteur
Durand, Pascal ULg

in Bulletin de la Société Théophile Gautier (2014), 36

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See detailThe phycologist Pierre Compère: his contribution to cyanobacterial studies
Golubic, Stjepko; Wilmotte, Annick ULg

in Plant Ecology and Evolution (2014), 147(3), 307-310

At the occasion of the 80th birthday of Pierre Compère, his rich career as a phycologist and cyanobacteriologist is placed in the context of the advances of the scientific theories, the evolution of the ... [more ▼]

At the occasion of the 80th birthday of Pierre Compère, his rich career as a phycologist and cyanobacteriologist is placed in the context of the advances of the scientific theories, the evolution of the cyanobacterial taxonomy and the nomenclatural discussions linked to the utilization of two different Codes of nomenclature. [less ▲]

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See detailPrediction of mean and turbulent kinetic energy in rectangular shallow reservoirs
Camnasio, Erica; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Engineering Applications of Computational Fluid Mechanics (2014), 8(4),

Shallow rectangular reservoirs are common structures in urban hydraulics and river engineering. Despite their simple geometry, complex symmetric and asymmetric flow fields develop in such reservoirs ... [more ▼]

Shallow rectangular reservoirs are common structures in urban hydraulics and river engineering. Despite their simple geometry, complex symmetric and asymmetric flow fields develop in such reservoirs, depending on their expansion ratio and length-to-width ratio. The original contribution of this study is the analysis of the kinetic energy content of the mean flow, based on UVP velocity measurements carried throughout the reservoir in eleven different geometric configurations. A new relationship is derived between the specific mean kinetic energy and the reservoir shape factor. For most considered geometric configurations, leading to four different flow patterns, the experimentally observed flow fields and mean kinetic energy contents are successfully reproduced by an operational numerical model based on the depth-averaged flow equations and a two-length-scale k-e turbulence closure. The analysis also highlights the better performance of this depth-averaged k-e model compared to an algebraic turbulence model. Finally, the turbulent kinetic energy in the reservoir is derived from the experimental measurements and the corresponding numerical predictions based on the k-e model agree satisfactorily in the main jet but not in the recirculation zones. [less ▲]

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See detail"Über Ländergrenzen hinaus" - Der Deutsche Buchpreis und seine Wirkung
Houscheid, Karin ULg

in Literaturkritik.de (2014)

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See detailControl of molecular dynamics with zero-area fields. application to molecular orientation and photodissociation
Sugny, Dominique; Vranckx, Stéphane; Ndong, Mamadou et al

in Physical Review A (2014), 90

The constraint of time-integrated zero area on the laser field is a fundamental requirement, both theoretically and experimentally, in the control of molecular dynamics. By using techniques of local and ... [more ▼]

The constraint of time-integrated zero area on the laser field is a fundamental requirement, both theoretically and experimentally, in the control of molecular dynamics. By using techniques of local and optimal control theory, we show how to enforce this constraint in two benchmark control problems, namely, molecular orientation and photofragmentation. The origin and the physical implications for the dynamics of this zero-area control field are discussed. [less ▲]

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See detailBook Review: Ralf Brand and Sarah Fregonese 2013: The Radicals’ City: Urban Environment, Polarisation, Cohesion. Surrey: Ashgate.
Farah, Jihad ULg

in International Journal of Urban and Regional Research (2014), 38(6),

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See detailComparison of the Decomposition VOC Profile during Winter and Summer in a Moist, Mid-latitude (Cfb) Climate
Forbes, Shari L.; Perrault, Katelynn A.; Stefanuto, Pierre-Hugues ULg et al

in PLoS ONE (2014), 9(e113681), 1-11

The investigation of volatile organic compounds (VOCs) associated with decomposition is an emerging field in forensic taphonomy due to their importance in locating human remains using biological detectors ... [more ▼]

The investigation of volatile organic compounds (VOCs) associated with decomposition is an emerging field in forensic taphonomy due to their importance in locating human remains using biological detectors such as insects and canines. A consistent decomposition VOC profile has not yet been elucidated due to the intrinsic impact of the environment on the decomposition process in different climatic zones. The study of decomposition VOCs has typically occurred during the warmer months to enable chemical profiling of all decomposition stages. The present study investigated the decomposition VOC profile in air during both warmer and cooler months in a moist, mid-latitude (Cfb) climate as decomposition occurs year-round in this environment. Pig carcasses (Sus scrofa domesticus L.) were placed on a soil surface to decompose naturally and their VOC profile was monitored during the winter and summer months. Corresponding control sites were also monitored to determine the natural VOC profile of the surrounding soil and vegetation. VOC samples were collected onto sorbent tubes and analyzed using comprehensive two-dimensional gas chromatography – time-of-flight mass spectrometry (GC6GC-TOFMS). The summer months were characterized by higher temperatures and solar radiation, greater rainfall accumulation, and comparable humidity when compared to the winter months. The rate of decomposition was faster and the number and abundance of VOCs was proportionally higher in summer. However, a similar trend was observed in winter and summer demonstrating a rapid increase in VOC abundance during active decay with a second increase in abundance occurring later in the decomposition process. Sulfur-containing compounds, alcohols and ketones represented the most abundant classes of compounds in both seasons, although almost all 10 compound classes identified contributed to discriminating the stages of decomposition throughout both seasons. The advantages of GC6GC-TOFMS were demonstrated for detecting and identifying trace levels of VOCs, particularly ethers, which are rarely reported as decomposition VOCs. [less ▲]

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See detailLes inhibiteurs de la PSCK9: une innovation majeure dans le traitement des dyslipidémies ?
PAQUOT, Nicolas ULg

in ABD- le supplément du médecin (2014), 57(6), 6-7

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See detailMapping French terms in a Belgian guideline on heart failure to international classifications and nomenclatures: the devil is in the detail.
Jamoulle, Marc ULg; Cardillo, Elena; Roumier, Joseph et al

in Informatics in Primary Care (2014), 4

Introduction: With growing sophistication of eHealth platforms, the ability increases to share medical information across patients, health care providers, institutions and across borders. This implies ... [more ▼]

Introduction: With growing sophistication of eHealth platforms, the ability increases to share medical information across patients, health care providers, institutions and across borders. This implies more stringent demands on the quality of data-entry at the point-of-care. Non-native English speaking general practitioners experience difficulties in interacting with international classification systems and nomenclatures to facilitate the secondary use of their data and to ensure semantic interoperability. Aim: To identify words and phrases pertaining to the heart failure domain and to explore the difficulties in mapping to corresponding concepts in ICPC-2, ICD-10, SNOMED-CT, and UMLS. Methods: The medical concepts in a Belgian guideline for General Practitioners (GPs) in its French version were extracted manually and coded first in ICPC-2, then ICD-10 by a physician, an expert in classification systems. In addition, mappings were sought with SNOMED-CT and UMLS concepts, using the UMLS SNOMED-CT browser. Results: We retained 143 words and phrases, of which 128 referred to a single concept (1-to-1 mapping), while 15 referred to 2 or more concepts (1-to-n mapping to ICPC rubrics or to the other nomenclatures). In the guideline, words or phrases were often too general for adequate correspondence. Marked discrepancy between semantic tags and types was found. Conclusion: This study illustrates the variability of the various international classifications and nomenclatures, the need for structured guidelines with more attention to precise wording, and the need for classification expertise embedded in sophisticated terminological resources. End-users need support to perform their clinical work in their own language, while still assuring standardized and semantic interoperable medical registration. Collaboration between computational linguists, knowledge engineers, health informaticians and domain experts is needed. [less ▲]

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See detailLa bibliothèque ouverte : hommage à Christine Pagnoulle
Decoster, Sara ULg

in Culture, le Magazine Culturel de l'Université de Liège (2014), hors série

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See detailDépression et diabète de type 2. Analyse étiopathogènique d'une comorbidité fréquente
LUPPENS, David ULg; PIETTE, Catherine ULg; RADERMECKER, R.P et al

in Revue Médicale de Liège (2014), 69(11), 611-617

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See detailTrajectory-Based Supplementary Damping Control for Power System Electromechanical Oscillations
Wang, Da ULg; Glavic, Mevludin ULg; Wehenkel, Louis ULg

in IEEE Transactions on Power Systems (2014), 29(6), 2835-2845

This paper considers a trajectory-based approach to determine control signals superimposed to those of existing controllers so as to enhance the damping of electromechanical oscillations. This approach is ... [more ▼]

This paper considers a trajectory-based approach to determine control signals superimposed to those of existing controllers so as to enhance the damping of electromechanical oscillations. This approach is framed as a discrete-time, multi-step optimization problem which can be solved by model-based and/or by learning-based methods. This paper proposes to apply a model-free tree-based batch mode Reinforcement Learning (RL) algorithm to perform such a supplementary damping control based only on information collected from observed trajectories of the power system. This RL-based supplementary damping control scheme is first implemented on a single generator and then several possibilities are investigated for extending it to multiple generators. Simulations are carried out on a 16-generators medium size power system model, where also possible benefits of combining this RL-based control with Model Predictive Control (MPC) are assessed. [less ▲]

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See detailLa dépression à l'adolescence: Quels signes ? Quand s'inquiéter ?
Boulard, Aurore ULg

in Eduquer : Tribune Laïque (2014), 109

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See detailInfinite self-shuffling words
Charlier, Emilie ULg; Kamae, Teturo; Puzynina, Svetlana et al

in Journal of Combinatorial Theory - Series A (2014), 128

In this paper we introduce and study a new property of infinite words: An infinite word x, with values in a finite set A, is said to be k-self-shuffling (k≥2) if there exists a shuffle of k copies of x ... [more ▼]

In this paper we introduce and study a new property of infinite words: An infinite word x, with values in a finite set A, is said to be k-self-shuffling (k≥2) if there exists a shuffle of k copies of x which produces x. We are particularly interested in the case k=2, in which case we say x is self-shuffling. This property of infinite words is shown to be independent of the complexity of the word as measured by the number of distinct factors of each length. Examples exist from bounded to full complexity. It is also an intrinsic property of the word and not of its language (set of factors). For instance, every aperiodic word contains a non-self-shuffling word in its shift orbit closure. While the property of being self-shuffling is a relatively strong condition, many important words arising in the area of symbolic dynamics are verified to be self-shuffling. They include for instance the Thue–Morse word fixed by the morphism 0↦01, 1↦10. As another example we show that all Sturmian words of intercept 0<ρ<1 are self-shuffling (while those of intercept ρ=0 are not). Our characterization of self-shuffling Sturmian words can be interpreted arithmetically in terms of a dynamical embedding and defines an arithmetic process we call the stepping stone model. One important feature of self-shuffling words stems from their morphic invariance: The morphic image of a self-shuffling word is self-shuffling. This provides a useful tool for showing that one word is not the morphic image of another. In addition to its morphic invariance, this new notion has other unexpected applications particularly in the area of substitutive dynamical systems. For example, as a consequence of our characterization of self-shuffling Sturmian words, we recover a number theoretic result, originally due to Yasutomi, on a classification of pure morphic Sturmian words in the orbit of the characteristic. [less ▲]

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See detailPoints d'appui
Jacquemain, Marc ULg

in SociologieS (2014)

L'article discute un grand résumé de Jan Spurk. Il met le doigt sur la contradiction dans ce "grand résumé" entre l'assomption que je le "je" est au coeur du capitalisme contemporain et le fait de confier ... [more ▼]

L'article discute un grand résumé de Jan Spurk. Il met le doigt sur la contradiction dans ce "grand résumé" entre l'assomption que je le "je" est au coeur du capitalisme contemporain et le fait de confier au sujet la tâche de l'émancipation de ce même capitalisme. Il propose de relever, dans différents courants de la littérature contemporaine de sciences sociales, les éléments qui plaident pour un "sujet" doté d'une capacité empirique de résistance au capitalisme. [less ▲]

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See detailRecommandations européennes concernant la prise en charge de l'embolie pulmonaire.
MELISSOPOULOU, Maria ULg; ANCION, Arnaud ULg; LANCELLOTTI, Patrizio ULg

in Revue Medicale de Liege (2014), 69(11), 594-599

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See detailA new long-tailed bsal bird from the Lower Cretaceous of north-eastern China
Lefevre, Ulysse ULg; Hu, Dongyu; Escuillié, François et al

in Biological Journal of the Linnean Society (2014), 113(3), 790-804

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See detailStochastic modelling of reservoir sedimentation in a semi-arid watershed
Adam, Nicolas; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Water Resources Management (2014)

Sedimentation in large reservoirs is a major concern in semi-arid regions characterized by severe seasonal water scarcity. As a contribution to improved sediment management, this study analyses the real ... [more ▼]

Sedimentation in large reservoirs is a major concern in semi-arid regions characterized by severe seasonal water scarcity. As a contribution to improved sediment management, this study analyses the real case of the reservoir of Sidi Yacoub in the north of Algeria. First, a dynamic model of the reservoir was set up and used to estimate past water and sediment inflows (period 1990-2010) based on data recorded by the dam operator and measurements at a gauging station located downstream of the reservoir. Second, in a stochastic framework using the statistical characteristics of inflow and outflow discharges, a projection of future sedimentation was performed until 2030, assuming stationarity of the statistical distributions. Third, the model was used to investigate the influence of possible climate change and to quantify the positive effects of soil conservation measures upstream. [less ▲]

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See detailCompte rendu de "Où est passé la critique sociale", P. Corcuff, La découverte, 2013
Frère, Bruno ULg

in SociologieS (2014)

L’ouvrage dont Philippe Corcuff nous suggère ici un grand résumé est stimulant à plus d’un titre. Comme à son habitude l’auteur fait montre d’une étonnante faculté à circuler entre les différents espaces ... [more ▼]

L’ouvrage dont Philippe Corcuff nous suggère ici un grand résumé est stimulant à plus d’un titre. Comme à son habitude l’auteur fait montre d’une étonnante faculté à circuler entre les différents espaces de réflexion de l’agir humain, balayant tour à tour le champ de la sociologie, de la philosophie, du cinéma, de la littérature, de l’engagement social et politique ou de la culture populaire. Passant de Michel Jonaz à Foucault, de Weber à Al Pacino, de Marcos à Magris, Corcuff jongle assez magistralement avec des univers distincts que nos habitudes intellectuelles aiment séparer tantôt par souci prétendu de « scientificité » tantôt parce que, bon gré mal gré, nos esprits de chercheurs en sciences humaines ont été configurés de telle sorte que les passerelles entre divers champs de réflexions possibles (artistiques, politiques, sociologiques, etc.) ne se construisent même plus. Je voudrais donc ouvrir la discussion autour de Où est passé la critique sociale ? en saluant l’audace des ponts entrepris par Philippe Corcuff. Que l’on accepte de le suivre sur chacun d’entre eux ou pas n’enlève rien à la qualité de cette tentative intellectuellement risquée (tant les espaces parcourus sont vastes) à l’heure où la doxa académique, comme dirait Bourdieu, voudrait que nous nous enfermions tous exclusivement dans l’ultra-spécialisation scientifique de micro-catégories du savoir rassemblées dans une case de la sous-spécialité de la discipline que nous avons choisi. Cela afin de parvenir à pointer du doigt un détail qui sera jugé suffisamment original par les rares pairs aussi spécialisés que nous pour décrocher le graal d’une publication dans une sacro-sainte revue rankée. Ainsi, Corcuff semble nous dire : je ne suis pas spécialiste des gender studies mais j’ose évoquer le féminisme. Je ne suis pas spécialiste de la Grèce Antique mais j’ose citer Aristote. On se moque du contenu des textes de tel chanteur populaire, mais j’ose indiquer en quoi il recèle, au même titre que le féminisme ou Aristote, des ressources pour construire une sociologie ou, plus simplement, une esquisse de pensée analytique. Corcuff démontre qu’il est possible de rompre les barrières, de fréquenter des terres improbables pour faire naître le plaisir de la réflexion. Et c’est très heureux. Cette appréciation globale posée, je voudrais à présent entrer dans le vif du sujet et structurer mon commentaire en deux temps. Le premier voudrait insister sur les deux principales qualités des deux textes. De par la variété des paradigmes sociologiques, philosophiques, anthropologiques ou historiques convoqués, Où est passée la critique sociale ? et son résumé dévoilent un intérêt pédagogique singulier pour tout qui désire fréquenter ces disciplines. D’autre part, l’un des trois axes de l’ouvrage repérés par Corcuff dans son grand résumé mérite pour sa part clairement l’intérêt des spécialistes contemporains de la critique sociale. Le second temps de mon commentaire traitera alors de l’écueil que je pense cette fois déceler dans le résumé et l’ouvrage. Cet écueil illustre d’ailleurs une légère insatisfaction ressentie à l’égard de plusieurs ouvrages de l’auteur, insatisfaction précisément due à la frustration de ne pas voir l’originalité de sa démarche être conduite à son terme. Pour le dire rapidement, je chercherai à indiquer que, d’une certaine manière, la tentative de Corcuff a le défaut de ses qualités : il en fait trop et trop peu à la fois. Tout se passe comme si l’ouvrage – et le résumé – n’étaient qu’un succession de notes éparses qui se succèdent au sujet d’un très grand nombre d’auteurs, cités parfois lapidairement, souvent très rapidement, sur un concept ou l’autre, jamais développé de façon systématique, en arguant qu’au bout du compte, la démarche se justifie par la légitimité du bricolage en sociologie. A ce titre, l’ouvrage peut parfois apparaître redondant. Il semble en effet ressasser tout du long la même idée (intéressante au demeurant) d’une sociologie comme boîte à outil, assumant son incomplétude et ses insuffisances, en la déclinant il est vrai sous plusieurs angles. Ceci sans jamais véritablement entrer dans le vif du sujet et entreprendre soit l’approfondissement théorique de son intuition fondamentale soit son application empirique dans une enquête approfondie. [less ▲]

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See detailComment je traite … Recommandations pour surveiller et optimiser un traitement médicamenteux en cours
SCHEEN, André ULg

in Revue Médicale de Liège (2014), 69(11), 581-585

Any pharmacological treatment should ideally be effective and safe. The supervision of an ongoing therapy should control that individualized goals are reached while tolerance and safety are present. In ... [more ▼]

Any pharmacological treatment should ideally be effective and safe. The supervision of an ongoing therapy should control that individualized goals are reached while tolerance and safety are present. In case of not reaching the predefined objectives, the causes of failure should first be screened (for instance, exclusion of poor patient compliance), and the treatment should be then optimized : dose adjustment, add-on of another drug (if possible synergistic combination) and/or shift to a more effective pharmacological therapy. In some cases, therapeutic monitoring may be useful or even mandatory in order to better adjust drug dosing and thus guarantee both efficacy and safety. [less ▲]

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See detailDon / Langage / Contretemps. Diagonales giovannangeliennes. Actes de la rencontre autour du travail de Daniel Giovannangeli. Université Saint-Louis Bruxelles, 2 mai 2014
Gavray, Marc-Antoine ULg; Gély, Raphaël; Richard, Sébastien

in Bulletin d'Analyse Phénoménologique (2014), 10(11),

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See detailEstetrol attenuates neonatal hypoxic–ischemic brain injury
Tskitishvili, Ekaterine ULg; Nisolle, Michelle ULg; Munaut, Carine ULg et al

in Experimental Neurology (2014), 261

Estetrol (E4) is a recently described natural estrogen with four hydroxyl-groups that is synthesized exclusively during pregnancy by the human fetal liver. It has important antioxidative activity. The aim ... [more ▼]

Estetrol (E4) is a recently described natural estrogen with four hydroxyl-groups that is synthesized exclusively during pregnancy by the human fetal liver. It has important antioxidative activity. The aim of the present study was to define the importance of E4 in the attenuation of neonatal hypoxic-ischemic encephalopathy. Antioxidative effect of 650μM, 3.25mM and 6.5mM E4 on primary hippocampal cell cultures was studied before/after H202-induced oxidative stress. To examine oxidative stress and cell viability, lactate dehydrogenase activity and cell proliferation colorimetric assays were performed. To study the neuroprotective and therapeutic effects of E4 in vivo neonatal hypoxic-ischemic encephalopathy model of 7-day-old newborn rat pups was used. The neuroprotective and therapeutic effects of estetrol before/after hypoxic-ischemic insult was studied in 1mg/kg/day, 5mg/kg/day, 10mg/kg/day, 50mg/kg/day E4 pretreated/treated groups and compared with the sham and the vehicle treated groups. The body temperature of the rat pups was examined along with their body and brain weights. Brains were studied at the level of the hippocampus and cortex. Intact cell counting and expressions of microtubule-associated protein-2, doublecortin and vascular-endothelial growth factor were evaluated by histo- and immunohistochemistry. ELISAs were performed on blood samples to detect concentrations of S100B and glial fibrillary acidic protein as brain damage markers. This work reveals for the first time that E4 significantly decreases LDH activity and enhances cell proliferation in primary hippocampal neuronal cell cultures in vitro, and decreases the early gray matter loss and promotes neuro- and angiogenesis in vivo. [less ▲]

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See detailAn inverse modelling approach to estimate the hygric parameters of clay-based masonry during a Moisture Buffer Value test
Dubois, Samuel ULg; McGregor, Fionn; Evrard, Arnaud et al

in Building & Environment (2014), 81

This paper presents an inverse modelling approach for parameter estimation of a model dedicated to the description of moisture mass transfer in porous hygroscopic building materials. The hygric behaviour ... [more ▼]

This paper presents an inverse modelling approach for parameter estimation of a model dedicated to the description of moisture mass transfer in porous hygroscopic building materials. The hygric behaviour of unfired clay-based masonry samples is specifically studied here and the Moisture Buffer Value (MBV) protocol is proposed as a data source from which it is possible to estimate several parameters at once. Those include materials properties and experimental parameters. For this purpose, the mass of two clay samples with different compositions is continuously monitored during several consecutive humidity cycles in isothermal conditions. Independently of these dynamic experimental tests, their moisture storage and transport parameters are measured with standard steady-state methods. A simple moisture transfer model developed in COMSOL Multiphysics is used to predict the moisture uptake/release behaviour during the MBV tests. The set of model parameters values that minimizes the difference between simulated and experimental results is then automatically estimated using an inverse modelling algorithm based on Bayesian techniques. For materials properties, the optimized parameters values are compared to values that were experimentally measured in steady state. And because a precise understanding of parameters is needed to assess the confidence in the inverse modelling results, a sensitivity analysis of the model is also provided. [less ▲]

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See detailValidation of SCIAMACHY HDO/H2O measurements using the TCCON and NDACC-MUSICA networks
Scheepmaker, R. A.; Frankenberg, C.; Deutscher, N. M. et al

in Atmospheric Measurement Techniques. Papers in Open Discussion (2014), 7(11), 11799--11851

Measurements of the atmospheric HDO/H2O ratio help us to better understand the hydrological cycle and improve models to correctly simulate tropospheric humidity and therefore climate change. We present an ... [more ▼]

Measurements of the atmospheric HDO/H2O ratio help us to better understand the hydrological cycle and improve models to correctly simulate tropospheric humidity and therefore climate change. We present an updated version of the column-averaged HDO/H2O ratio dataset from the SCanning Imaging Absorption spectroMeter for Atmospheric CHartographY (SCIAMACHY). The dataset is extended with two additional years, now covering 2003–2007, and is validated against co-located ground-based total column delta-D measurements from Fourier-Transform Spectrometers (FTS) of the Total Carbon Column Observing Network (TCCON) and the Network for the Detection of Atmospheric Composition Change (NDACC, produced within the framework of the MUSICA project). Even though the time overlap between the available data is not yet ideal, we determined a mean negative bias in SCIAMACHY delta-D of -35±30‰ compared to TCCON and -69±15‰ compared to MUSICA (the uncertainty indicating the station-to-station standard deviation). The bias shows a latitudinal dependency, being largest (about -60 to -80‰) at the highest latitudes and smallest (about -20 to -30‰) at the lowest latitudes. We have tested the impact of an offset correction to the SCIAMACHY HDO and H2O columns. This correction leads to a humidity and latitude dependent shift in delta-D and an improvement of the bias by 27 ‰, although it does not lead to an improved correlation with the FTS measurements nor to a strong reduction of the latitudinal dependency of the bias. The correction might be an improvement for dry, high-altitude areas, such as the Tibetan Plateau and the Andes region. For these areas, however, validation is currently impossible due to a lack of ground stations. The mean standard deviation of single-sounding SCIAMACHY–FTS differences is ~115 ‰, which is reduced by a factor ~2 when we consider monthly means. When we relax the strict matching of individual measurements and focus on the mean seasonalities using all available FTS data, we find that the correlation coefficients between SCIAMACHY and the FTS networks improve from 0.2 to 0.7–0.8. Certain ground stations show a clear asymmetry in delta-D during the transition from the dry to the wet season and back, which is also detected by SCIAMACHY. This asymmetry points to a transition in the source region temperature or location of the water vapor, and shows the added information that HDO/H2O measurements provide, if used in combination with variations in humidity. [less ▲]

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See detailA BCool magnetic snapshot survey of solar-type stars
Marsden, S.C.; Petit, P.; Jeffers, S.V. et al

in Monthly Notices of the Royal Astronomical Society (2014), 444

We present the results of a major high-resolution spectropolarimetric BCool project magnetic survey of 170 solar-type stars. Surface magnetic fields were detected on 67 stars, with 21 classified as mature ... [more ▼]

We present the results of a major high-resolution spectropolarimetric BCool project magnetic survey of 170 solar-type stars. Surface magnetic fields were detected on 67 stars, with 21 classified as mature solar-type stars, a result that increases by a factor of 4 the number of mature solar-type stars on which magnetic fields have been observed. In addition, a magnetic field was detected for 3 out of 18 of the subgiant stars surveyed. For the population of K-dwarfs, the mean value of |Bl| (|Bl|mean) was also found to be higher (5.7 G) than |Bl|mean measured for the G-dwarfs (3.2 G) and the F-dwarfs (3.3 G). For the sample as a whole, |Bl|mean increases with rotation rate and decreases with age, and the upper envelope for |Bl| correlates well with the observed chromospheric emission. Stars with a chromospheric S-index greater than about 0.2 show a high magnetic field detection rate and so offer optimal targets for future studies. This survey constitutes the most extensive spectropolarimetric survey of cool stars undertaken to date, and suggests that it is feasible to pursue magnetic mapping of a wide range of moderately active solar-type stars to improve our understanding of their surface fields and dynamos. [less ▲]

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See detailRetrofitting the suburbs: Insulation, density, urban form and location
Marique, Anne-Françoise ULg; Reiter, Sigrid ULg

in Environmental management and sustainable development (2014), 3(2), 138-153

The effects of urban sprawl have been well documented, particularly regarding energy consumption. Suburban neighbourhoods are known to be energy inefficient and urban sprawl is considered as a major issue ... [more ▼]

The effects of urban sprawl have been well documented, particularly regarding energy consumption. Suburban neighbourhoods are known to be energy inefficient and urban sprawl is considered as a major issue for sustainable development. To improve the energy efficiency of existing suburban urban fabrics is a major challenge that must be addressed to favour a sustainability transition of our built environment. In this context, this paper aims at investigating several scenarios that could be developed to improve the sustainability of existing suburban neighbourhoods: three main types of scenarios (building insulation, density, and urban form) and twelve sub-scenarios, which are focused on the possible evolution of the existing suburban building stocks, are proposed. Quantitative methods developed in previous research are used to assess and compare building and transportation energy consumption of a representative suburban case study. This application aims at investigating two main research questions: (1) "how to intervene in suburban neighbourhoods?" and (2) «where to intervene?" The main results of this application, which are focused on energy efficiency, are then studied in a larger framework to highlight their opportunities and constraints. The main findings of the paper are that, beyond the traditional polarisation of the debates on the energy efficiency of our built environment between the “compact” and the “sprawled” city, a new pragmatic paradigm, which is focused on the smooth densification of existing suburban neighbourhoods, can make them evolve towards greater sustainability. [less ▲]

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See detailAu cœur de la réforme des soins de santé mentale en Belgique : les coordinateurs de réseau
Thunus, Sophie ULg; Lorquet, Nadège ULg

in SociologieS (2014)

Inside the Belgian reform of mental health care delivery: network coordinators This article analyses the Belgian reform of mental health care delivery as a two steps-translation (Callon 1986): the ... [more ▼]

Inside the Belgian reform of mental health care delivery: network coordinators This article analyses the Belgian reform of mental health care delivery as a two steps-translation (Callon 1986): the problematization – the devising of a new mental health care model by policy makers, and the interessement – through which “local coordinators” tried to interest local actors to the new model. Based on empirical data, two evidences are stressed: the coordination function is conceived in different ways, ranging from intermediaries to mediators; and the interessement is influenced by systems of concrete action (Friedberg, 1997). Thus, it is argued that in case where translators are appointed to interest local actors to a problematization from the policy arena, their performance is better appraised by considering their commitment to behave as faithful intermediaries or as strategic mediators, and the informal games regulating their system of action. [less ▲]

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See detailLa prothèse valvulaire idéale n’existe toujours pas. Quels facteurs entrent en compte pour orienter les choix d’une valve mécanique ou biologique ?
GREGOIRE, Céline ULg; Nellessen, Eric; Defraigne, Jean-Olivier ULg et al

in Revue Médicale de Liège (2014), 69(11), 600-604

The prevalence of valvular heart diseases reaches 2.5% in the overall population. Aortic valve replacement is one of the most common surgical procedures. We report the story of a female patient whose ... [more ▼]

The prevalence of valvular heart diseases reaches 2.5% in the overall population. Aortic valve replacement is one of the most common surgical procedures. We report the story of a female patient whose aortic mechanical valve, implanted at the age of 54 years at the time of a mitral valve repair surgery, had to be replaced 14 years later, due to the development of a subvalvular pannus narrowing the valvular orifice. We use this clinical story to compare the advantages and disadvantages of repair surgery and valve replacement with a biological or mechanical prosthesis, and summarize the latest evidence for the choice of the most adequate prosthesis for a particular patient’s profile. [less ▲]

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See detailProjections graphiques de quelques espaces de la vie sociale au Japon
Badir, Sémir ULg

in Lexia (2014), 17-18

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See detailRaman hyperspectral imaging: a single tool to characterise pharmaceutical products
Netchacovitch, Lauranne ULg; De Bleye, Charlotte ULg; Chavez, Pierre-François ULg et al

in European Pharmaceutical Review (2014), 19(5), 8-11

Raman hyperspectral imaging is an increasingly used tool in the pharmaceutical field because it allows for the investigation of many characteristics on a solid sample. This paper delves into Raman ... [more ▼]

Raman hyperspectral imaging is an increasingly used tool in the pharmaceutical field because it allows for the investigation of many characteristics on a solid sample. This paper delves into Raman spectroscopy and imaging, including spectral and spatial information, and presents some applications of Raman hyperspectral imaging in the pharmaceutical field. [less ▲]

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See detailPractical aspects of genome-wide association interaction analysis.
Gusareva, Elena ULg; Van Steen, Kristel ULg

in Human Genetics (2014), 133(11), 1343-58

Large-scale epistasis studies can give new clues to system-level genetic mechanisms and a better understanding of the underlying biology of human complex disease traits. Though many novel methods have ... [more ▼]

Large-scale epistasis studies can give new clues to system-level genetic mechanisms and a better understanding of the underlying biology of human complex disease traits. Though many novel methods have been proposed to carry out such studies, so far only a few of them have demonstrated replicable results. Here, we propose a minimal protocol for genome-wide association interaction (GWAI) analysis to identify gene–gene interactions from large-scale genomic data. The different steps of the developed protocol are discussed and motivated, and encompass interaction screening in a hypothesis-free and hypothesisdriven manner. In particular, we examine a wide range of aspects related to epistasis discovery in the context of complex traits in humans, hereby giving practical recommendations for data quality control, variant selection or prioritization strategies and analytic tools, replication and meta-analysis, biological validation of statistical findings and other related aspects. The minimal protocol provides guidelines and attention points for anyone involved in GWAI analysis and aims to enhance the biological relevance of GWAI findings. At the same time, the protocol improves a better assessment of strengths and weaknesses of published GWAI methodologies. [less ▲]

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See detailDe l’usage des programmes électoraux. Compétition sur enjeux et attribution des compétences au sein du gouvernement wallon 2014-2019
Piet, Grégory ULg

in Revue de la Faculté de Droit de l'Université de Liège (2014), 3

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See detailPlutella xylostella (L.) infestations at varying temperatures induce the emission of specific volatile blends by Arabidopsis thaliana (L.) Heynh
Hien, Truong Thi Dieu ULg; Delory, Benjamin ULg; Brostaux, Yves ULg et al

in Plant Signaling & Behavior (2014)

The effect of combined abiotic and biotic factors on plant volatile organic compound (VOC) emissions is poorly understood. This study evaluated the VOC emissions produced by Arabidopsis thaliana (L.) Col ... [more ▼]

The effect of combined abiotic and biotic factors on plant volatile organic compound (VOC) emissions is poorly understood. This study evaluated the VOC emissions produced by Arabidopsis thaliana (L.) Col-0 subjected to three temperature regimes (17, 22, and 27 °C) in the presence and absence of Plutella xylostella larvae over two time intervals (0–4 and 4–8 h), in comparison to control plants. The analyses of VOCs emitted by Arabidopsis plants were made by headspace solid phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS). It was found that certain volatile groups (e.g., alcohols, ketones, aldehydes, and terpenes) are induced by both single factors (temperature or larval infestation) and combined factors (temperature and larvae interactions), whereas other volatile groups (e.g., isothiocyanates [ITCs] and nitrile) were specific to the experimental conditions. ITCs (mainly 4-methylpentyl isothiocyanate) were emitted from plants subjected to larval infestation at 17 and 27 °C after the two time intervals. The proportions of sulfides (mainly dimethyl disulfide) and 4-(methylthio) butanenitrile were significantly higher on herbivore-infested plants at 22 °C compared to the other treatments. Overall, our findings indicate that changes in all experimental conditions caused significant changes to the VOC emissions of Arabidopsis plants. Therefore, the interaction between temperature and larval feeding may represent an important factor determining the variability of volatile emissions by plants subjected to multiple simultaneous factors. [less ▲]

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See detailLa représentation commerciale comme objet principal du contrat
Kéfer, Fabienne ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2014), (2014/35),

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See detailInjury Risk Assessment of Non-Lethal Projectile Head Impacts
Oukara, Amar ULg; Robbe, Cyril; Nsiampa, Nestor et al

in The Open Biomedical Engineering Journal (2014), 8(2014), 75-83

Kinetic energy non-lethal projectiles are used to impart sufficient effect onto a person in order to deter uncivil or hazardous behavior with a low probability of permanent injury. Since their first use ... [more ▼]

Kinetic energy non-lethal projectiles are used to impart sufficient effect onto a person in order to deter uncivil or hazardous behavior with a low probability of permanent injury. Since their first use, real cases indicate that the injuries inflicted by such projectiles may be irreversible and sometimes lead to death, especially for the head impacts. Given the high velocities and the low masses involved in such impacts, the assessment approaches proposed in automotive crash tests and sports may not be appropriate. Therefore, there is a need of a specific approach to assess the lethality of these projectiles. In this framework, some recent research data referred in this article as “force wall approach” suggest the use of three lesional thresholds (unconsciousness, meningeal damages and bone damages) that depend on the intracranial pressure. Three corresponding critical impact forces are determined for a reference projectile. Based on the principle that equal rigid wall maximal impact forces will produce equal damage on the head, these limits can be determined for any other projectile. In order to validate the consistence of this innovative method, it is necessary to compare the results with other existing assessment methods. This paper proposes a comparison between the “force wall approach” and two different head models. The first one is a numerical model (Strasbourg University Finite Element Head Model-SUFEHM) from Strasbourg University; the second one is a mechanical surrogate (Ballistics Load Sensing Headform-BLSH) from Biokinetics. [less ▲]

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See detailCapacitated vehicle routing problem with sequence- based pallet loading and axle weight constraints
Pollaris, Hanne; Braekers, Kris; Caris, An et al

in EURO Journal on Transportation and Logistics (2014)

In this paper, we introduce and study the capacitated vehicle routing problem with sequence-based pallet loading and axle weight constraints. To the best of our knowledge, it is the first time that axle ... [more ▼]

In this paper, we introduce and study the capacitated vehicle routing problem with sequence-based pallet loading and axle weight constraints. To the best of our knowledge, it is the first time that axle weight restrictions are incorporated in a vehicle routing model. The aim of this paper is to demonstrate that incorporating axle weight restrictions in a vehicle routing model is possible and necessary for a feasible route planning. Axle weight limits impose a great challenge for transportation companies. Trucks with overloaded axles represent a significant threat for traffic safety and may cause serious damage to the road surface. Transporters face high fines when violating these limits. A mixed integer linear programming formulation for the capacitated vehicle routing problem with sequence-based pallet loading and axle weight constraints is provided. Results of the model are compared to the results of the model without axle weight restrictions. Computational experiments demonstrate that the model performs adequately and that the integration of axle weight constraints in vehicle routing models is required for a feasible route planning. [less ▲]

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See detailBrix, contre la modernité
Lorent, Fanny ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2014)

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See detailPiezoelectric vibration damping using resonant shunt circuits: an exact solution
Soltani, Payam ULg; Kerschen, Gaëtan ULg; Tondeau, Gilles et al

in Smart Materials & Structures (2014), 23

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See detailRetrievals of formaldehyde from ground-based FTIR and MAX-DOAS observations at the Jungfraujoch station and comparisons with GEOS-Chem and IMAGES model simulations
Franco, Bruno ULg; Hendrick, François; Van Roozendael, Michel et al

in Atmospheric Measurement Techniques. Papers in Open Discussion (2014), 7

As a ubiquitous product of the oxidation of many Volatile Organic Compounds (VOCs), formaldehyde (HCHO) plays a key role as a short-lived and reactive intermediate in the atmospheric photo-oxidation ... [more ▼]

As a ubiquitous product of the oxidation of many Volatile Organic Compounds (VOCs), formaldehyde (HCHO) plays a key role as a short-lived and reactive intermediate in the atmospheric photo-oxidation pathways leading to the formation of tropospheric ozone and secondary organic aerosols. In this study, HCHO profiles have been successfully retrieved from ground-based Fourier Transform Infrared (FTIR) solar spectra and UV-Visible Multi-AXis Differential Optical Absorption Spectroscopy (MAX-DOAS) scans recorded during the July 2010–December 2012 time period at the Jungfraujoch station (Swiss Alps, 46.5 N, 8.0 E, 3580ma.s.l.). Analysis of the retrieved products has revealed different vertical sensitivity between both remote sensing techniques. Furthermore, HCHO amounts simulated by two state-of-the-art Chemical Transport Models (CTMs), GEOS-Chem and IMAGESv2, have been compared to FTIR total columns and MAX-DOAS 3.6–8 km partial columns, accounting for the respective vertical resolution of each ground-based instrument. Using the CTMs outputs as intermediate, FTIR and MAX-DOAS retrievals have shown consistent seasonal modulations of HCHO throughout the investigated period, characterized by summertime maximum and wintertime minimum. Such comparisons have also highlighted that FTIR and MAX-DOAS provide complementary products for the HCHO retrieval above the Jungfraujoch station. [less ▲]

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See detailSensitivity of Greenland Ice Sheet surface mass balance to perturbations in sea surface temperature and sea ice cover: a study with the regional climate model MAR
Noel, Brice; Fettweis, Xavier ULg; van de Berg, W.J. et al

in Cryosphere (The) (2014), 8

During recent summers (2007–2012), several surface melt records were broken over the Greenland Ice Sheet (GrIS). The extreme summer melt resulted in part from a persistent negative phase of the North ... [more ▼]

During recent summers (2007–2012), several surface melt records were broken over the Greenland Ice Sheet (GrIS). The extreme summer melt resulted in part from a persistent negative phase of the North Atlantic Oscillation (NAO), favoring warmer atmospheric conditions than normal over the GrIS. Simultaneously, large anomalies in sea ice cover (SIC) and sea surface temperature (SST) were observed in the North Atlantic, suggesting a possible connection. To assess the direct impact of 2007–2012 SIC and SST anomalies on GrIS surface mass balance (SMB), a set of sensitivity experiments was carried out with the regional climate model MAR forced by ERA-Interim. These simulations suggest that perturbations in SST and SIC in the seas surrounding Greenland do not considerably impact GrIS SMB, as a result of the katabatic wind blocking effect. These offshore-directed winds prevent oceanic near-surface air, influenced by SIC and SST anomalies, from penetrating far inland. Therefore, the ice sheet SMB response is restricted to coastal regions, where katabatic winds cease. A topic for further investigation is how anomalies in SIC and SST might have indirectly affected the surface melt by changing the general circulation in the North Atlantic region, hence favoring more frequent warm air advection towards the GrIS. [less ▲]

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See detailCombined holography and thermography in a single sensor through image-plane holography at thermal infrared wavelengths
Georges, Marc ULg; Vandenrijt, Jean-François ULg; Thizy, Cédric ULg et al

in Optics Express (2014), 22(21), 25517-25529

Holographic interferometry in the thermal wavelengths range, combining a CO2 laser and digital hologram recording with a microbolometer array based camera, allows simultaneously capturing temperature and ... [more ▼]

Holographic interferometry in the thermal wavelengths range, combining a CO2 laser and digital hologram recording with a microbolometer array based camera, allows simultaneously capturing temperature and surface shape information about objects. This is due to the fact that the holograms are affected by the thermal background emitted by objects at room temperature. We explain the setup and the processing of data which allows decoupling the two types of information. This natural data fusion can be advantageously used in a variety of nondestructive testing applications. [less ▲]

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See detailProbabilistic Assessment of Lifetime of Low-Earth-Orbit Spacecraft: Uncertainty Propagation and Sensitivity Analysis
Dell'Elce, Lamberto ULg; Kerschen, Gaëtan ULg

in Journal of Guidance Control & Dynamics (2014)

This paper is devoted to the probabilistic uncertainty quantification of orbital lifetime estimation of low-altitude satellites. Specifically, given a detailed characterization of the dominant sources of ... [more ▼]

This paper is devoted to the probabilistic uncertainty quantification of orbital lifetime estimation of low-altitude satellites. Specifically, given a detailed characterization of the dominant sources of uncertainty, we map this input into a probabilistic characterization of the orbital lifetime through orbital propagation. Standard Monte Carlo propagation is first considered. The concept of drag correction is then introduced to facilitate the use of polynomial chaos expansions and to make uncertainty propagation computationally effective. Finally, the obtained probabilistic model is exploited to carry out stochastic sensitivity analyses, which in turn allow gaining insight into the impact uncertainties have on orbital lifetime. The proposed developments are illustrated using one CubeSat of the QB50 constellation. [less ▲]

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See detailSeasonal variations of wild boar Sus scrofa distribution in agricultural landscapes: a species distribution modelling approach
Morelle, Kevin ULg; Lejeune, Philippe ULg

in European Journal of Wildlife Research (2014)

Seasonal changes in the distribution of animals can have an important impact on the ecosystem. In agricultural landscapes, the seasonal movement of the wild boar Sus scrofa towards field crops often ... [more ▼]

Seasonal changes in the distribution of animals can have an important impact on the ecosystem. In agricultural landscapes, the seasonal movement of the wild boar Sus scrofa towards field crops often results in damages and makes control of the population difficult. The plasticity of the species to cope with different habitats is largely proven, but the environmental and human drivers of this seasonal habitat shift at the population scale remain largely unknown. Using MaxEnt and two seasonally distinct presence datasets, we contrasted the distribution of wild boar in southern Belgium during the growing and hunting seasons to (i) analyse seasonal drivers of the distribution and (ii) forecast the potential spread of the species north to its current distribution. We demonstrated that during the growing season, wild boar range almost double, owing to the cover and food provided by agricultural areas, thereby enhancing the movement and spread of the species. We found that the seasonal distribution of wild boar in agricultural lands is mostly influenced by the search for cover and food provided alternatively by forest and field crops. Interestingly, it seems that this search for cover operates under the constraint of a threshold distance. Our results indeed reveal an increased probability of presence not only in the vicinity of forests but also above a threshold distance of 865 m from the forest edge, suggesting that wild boar can overcome the dependence to forest cover. The forecast distribution of wild boar highlighted a potential increase of the current range into suitable habitat between 63 and 168 km2. To counteract the potential spread of the species into agricultural habitats and the consecutive damages, we insist on the need for the development of integrated management strategies, combining land use spatial configuration and wild boar spatial behaviour. [less ▲]

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See detailRèglements de juges : conséquences sur la peine et sur la saisine du juge de renvoi
Michiels, Olivier ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2014)

Le prévenu qui après avoir été condamné par défaut et sur opposition interjette seul appel de cette dernière décision ne peut voir sa situation aggravée quand bien même la juridiction d’appel s’est ... [more ▼]

Le prévenu qui après avoir été condamné par défaut et sur opposition interjette seul appel de cette dernière décision ne peut voir sa situation aggravée quand bien même la juridiction d’appel s’est déclarée incompétente provoquant de la sorte un règlement de juges qui se résout par son renvoi devant la cour d’assises. [less ▲]

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See detailEffects of Size and Dispersity of Microcrystalline Celluloses on Size, Structure and Stability of Nanocrystalline Celluloses Extracted by Acid Hydrolysis
Qi, Liu; Weiping, Hao; Yongguang, Yang et al

in Nano LIFE (2014), 4(4),

Nanocrystalline celluloses (NCCs) were separated from four commercial microcrystalline celluloses (MCCs) by an acid hydrolysis–sonication treatment. Transmission electron microscopy (TEM), atomic force ... [more ▼]

Nanocrystalline celluloses (NCCs) were separated from four commercial microcrystalline celluloses (MCCs) by an acid hydrolysis–sonication treatment. Transmission electron microscopy (TEM), atomic force microscopy (AFM), Fourier transform infrared (FTIR) spectrum, X-ray di®raction (XRD) and thermogravimetric analysis (TGA) were conducted to investigate the NCCs. MCCs with di®erent morphologies and particle sizes showed di®erent aggregation degrees. The aggregation of MCCs followed the order MCC1 > MCC3 > MCC2 > MCC4, which is the same order of the heights of the resulting NCCs. The best uniformity and thermal stability were characterized for NCC3, which was produced by MCC3 with smallest original particle size and good dispersity among the four MCCs. This result suggests that both the original particle size and dispersity of MCCs had signi¯cant e®ects on separated NCCs. [less ▲]

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See detailA closer look at the low frequency dynamics of vortex matter
Raes, Bart; de Souza Silva, Clecio C.; Silhanek, Alejandro ULg et al

in Physical Review. B : Condensed Matter (2014), 90

Using scanning susceptibility microscopy, we shed new light on the dynamics of individual superconducting vortices and examine the hypotheses of the phenomenological models traditionally used to explain ... [more ▼]

Using scanning susceptibility microscopy, we shed new light on the dynamics of individual superconducting vortices and examine the hypotheses of the phenomenological models traditionally used to explain the macroscopic ac electromagnetic properties of superconductors. The measurements, carried out on a 2H-NbSe2 single crystal at relatively high temperature T = 6.8 K, show a linear amplitude dependence of the global ac-susceptibility for excitation amplitudes between 0.3 and 2.6 Oe. We observe that the low amplitude response, typically attributed to the oscillation of vortices in a potential well defi ned by a single, relaxing, Labusch constant, actually corresponds to strongly non-uniform vortex shaking. This is particularly pronounced in the fi eld-cooled disordered phase, which undergoes a dynamic reorganization above 0.8 Oe as evidenced by the healing of lattice defects and a more uniform oscillation of vortices. These observations are corroborated by molecular dynamics simulations when choosing the microscopic input parameters from the experiments. The theoretical simulations allow us to reconstruct the vortex trajectories providing deeper insight in the thermally induced hopping dynamics and the vortex lattice reordering. [less ▲]

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See detailThe use of Ion Mobility Mass Spectrometry for isomer composition determination extracted from Se-rich yeast
Far, Johann ULg; Delvaux, Cédric ULg; Kune, Christopher ULg et al

in Analytical Chemistry (2014), just accepted

The isomer ratio determination of a selenium-containing metabolite produced by Se-rich yeast was performed. Electrospray Ionization and Ion Mobility Mass Spectrometry (IM-MS) were unsuccessfully used in ... [more ▼]

The isomer ratio determination of a selenium-containing metabolite produced by Se-rich yeast was performed. Electrospray Ionization and Ion Mobility Mass Spectrometry (IM-MS) were unsuccessfully used in order to resolve the isomers according to their Collisional Cross Section (CCS) difference. The isomer ratio determination of 2,3-dihydroxypropionylselenocystathionine was performed after multidimensional liquid chromatography preconcentration from a water extract of Se-rich yeast using preparative size exclusion, anion exchange and capillary reverse phase columns coupled to IM-MS. 4’-nitrobenzo-15-crown-5 ether, a Selective Shift Reagent (SSR), was added after the last chromatographic dimension in order to specifically increase the CCS of one of the isomers by the formation of a stable host-guest system with the crown-ether . Both isomers were consequently fully resolved by IM-MS and the relative ratio of the isomers was determined: 11-13% and 87-89%. The present data compared favorably with literature to support the analytical strategy despite the lack of authentic standard for method validation. In addition, computational chemistry methods were successfully applied to design the SSR and to support the experimental data. [less ▲]

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See detailA facile and fast electrochemical route to produce functional few-layer graphene sheets for lithium battery anode application
Ouhib, Farid ULg; Aqil, Abdelhafid ULg; Thomassin, Jean-Michel ULg et al

in Journal of Materials Chemistry A (2014), 2(37), 15298-15302

A simple approach for the production of polymer functionalized graphene nanosheets is reported. The resulting polyacrylonitrile chemisorbed on graphene sheets is made of 1 to 2 layers, with a large ... [more ▼]

A simple approach for the production of polymer functionalized graphene nanosheets is reported. The resulting polyacrylonitrile chemisorbed on graphene sheets is made of 1 to 2 layers, with a large majority of graphene single-layers. This novel functionalized graphene exhibits good cycling stability as an anode in Li-ion batteries without a conductive additive or binder. [less ▲]

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See detailClassical analogy for the deflection of flux avalanches by a metallic layer
Brisbois, Jérémy ULg; Vanderheyden, Benoît ULg; Colauto, Fabiano et al

in New Journal of Physics (2014), 16(10), 103003

Sudden avalanches of magnetic flux bursting into a superconducting sample undergo deflections of their trajectories when encountering a conductive layer deposited on top of the superconductor. Remarkably ... [more ▼]

Sudden avalanches of magnetic flux bursting into a superconducting sample undergo deflections of their trajectories when encountering a conductive layer deposited on top of the superconductor. Remarkably, in some cases the flux is totally excluded from the area covered by the conductive layer. We present a simple classical model that accounts for this behaviour and considers a magnetic monopole approaching a semi-infinite conductive plane. This model suggests that magnetic braking is an important mechanism responsible for avalanche deflection. [less ▲]

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See detailMulticenter implementation of geriatric assessment in Belgian patients with cancer: A survey on treating physicians' general experiences and expectations.
Kenis, Cindy; Kenis, Cindy; Heeren, Pieter et al

in Journal of geriatric oncology (2014), 5(4), 431-438

OBJECTIVES: The aim of this study is to identify treating physicians' general experiences and expectations regarding geriatric assessment (GA) in older patients with cancer. MATERIALS AND METHODS: A ... [more ▼]

OBJECTIVES: The aim of this study is to identify treating physicians' general experiences and expectations regarding geriatric assessment (GA) in older patients with cancer. MATERIALS AND METHODS: A survey was carried out in 9 Belgian hospitals, which participated in a national GA implementation project focusing on older patients with cancer. A newly developed questionnaire was completed by their treating physicians. Data collection comprised of reviewing hospital data, general respondent data, and treating physicians' general experiences and expectations regarding GA. Descriptive statistics were calculated. RESULTS: Eighty-two physicians from 9 hospitals participated. The GA team composition can vary substantially, with a nurse as core member. Ideally, all older patients with cancer in whom a treatment decision is necessary, should benefit from the GA. Nearly all GA domains are reported as very important. Availability of GA results can be improved. Treating physicians want geriatricians to coordinate geriatric recommendations related to the identified GA problems, and expect from trained healthcare workers (THCWs) to collect GA data, to report GA results, and to follow-up the implementation of geriatric recommendations. CONCLUSION: This study identifies relevant information for improving the implementation of GA in older patients with cancer in Belgium and reveals priorities for a THCW from the treating physician's point of view. To increase the effectiveness of GA, further efforts are needed to improve the implementation of geriatric recommendations. [less ▲]

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See detailTIGRE: A new robotic spectroscopy telescope at Guanajuato, Mexico
Schmitt, J. H. M. M.; Schröder, K.-P.; Rauw, Grégor ULg et al

in Astronomische Nachrichten (2014), 335

TIGRE is a new robotic spectroscopy telescope located in central Mexico at the La Luz Observatory of the University of Guanajuato. The 1.2 m telescope is fiber-coupled to an échelle spectrograph with a ... [more ▼]

TIGRE is a new robotic spectroscopy telescope located in central Mexico at the La Luz Observatory of the University of Guanajuato. The 1.2 m telescope is fiber-coupled to an échelle spectrograph with a spectral resolving power exceeding 20 000 over most of the covered spectral range between 3800 Å and 8800 Å, with a small gap of 130 Å around 5800 Å. TIGRE operates robotically, i.e. it (normally) carries out all observations without any human intervention, including, in particular, the target selection in any given observing night. In this paper we describe the properties of the TIGRE instrumentation and its technical realization, as well as our first operational experience with the performance and efficiency of the overall system. Finally, we present some examples of recent TIGRE observations. [less ▲]

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See detailQTL analysis and candidate gene mapping for the polyphenol content in cider apple
Verdu, Cindy ULg; Guyot, Sylvain; Childebrand, Nicolas et al

in PLoS ONE (2014), 9(10), 107103

Polyphenols have favorable antioxidant potential on human health suggesting that their high content is responsible for the beneficial effects of apple consumption. They control the quality of ciders as ... [more ▼]

Polyphenols have favorable antioxidant potential on human health suggesting that their high content is responsible for the beneficial effects of apple consumption. They control the quality of ciders as they predominantly account for astringency, bitterness, color and aroma. In this study, we identified QTLs controlling phenolic compound concentrations and the average polymerization degree of flavanols in a cider apple progeny. Thirty two compounds belonging to five groups of phenolic compounds were identified and quantified by reversed phase liquid chromatography on both fruit extract and juice, over three years. The average polymerization degree of flavanols was estimated in fruit by phloroglucinolysis coupled to HPLC. Parental maps were built using SSR and SNP markers and used for the QTL analysis. Sixty-nine and 72 QTLs were detected on 14 and 11 linkage groups of the female and male maps, respectively. A majority of the QTLs identified in this study are specific to this population, while others are consistent with previous studies. This study presents for the first time in apple, QTLs for the mean polymerization degree of procyanidins, for which the mechanisms involved remains unknown to this day. Identification of candidate genes underlying major QTLs was then performed in silico and permitted the identification of 18 enzymes of the polyphenol pathway and six transcription factors involved in the apple anthocyanin regulation. New markers were designed from sequences of the most interesting candidate genes in order to confirm their co-localization with underlying QTLs by genetic mapping. Finally, the potential use of these QTLs in breeding programs is discussed. [less ▲]

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See detailMicrocrystalline cellulose, a direct compression binder in a quality by design environment—A review
Thoorens, Grégory; Krier, Fabrice ULg; Leclercq, Bruno et al

in International Journal of Pharmaceutics (2014), 473(1-2), 64-72

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See detailThe 2.35 year itch of Cygnus OB2 #9. III. X-ray and radio emission analysis based on 3D hydrodynamical modelling
Parkin, E. R.; Pittard, J. M.; Nazé, Yaël ULg et al

in Astronomy and Astrophysics (2014), 570

Context. The wind-wind collision in a massive star binary system leads to the generation of high temperature shocks that emit at X-ray wavelengths and, if particle acceleration is effective, may exhibit ... [more ▼]

Context. The wind-wind collision in a massive star binary system leads to the generation of high temperature shocks that emit at X-ray wavelengths and, if particle acceleration is effective, may exhibit non-thermal radio emission. Cyg OB2#9 is one of a small number of massive star binary systems in this class. <BR /> Aims: X-ray and radio data recently acquired as part of a project to study Cyg OB2#9 are used to constrain physical models of the binary system, providing in-depth knowledge about the wind-wind collision and the thermal, and non-thermal, emission arising from the shocks. <BR /> Methods: We use a 3D, adaptive mesh refinement simulation (including wind acceleration, radiative cooling, and the orbital motion of the stars) to model the gas dynamics of the wind-wind collision. The simulation output is used as the basis for radiative transfer calculations considering the thermal X-ray emission and the thermal/non-thermal radio emission. <BR /> Results: The flow dynamics in the simulation show that wind acceleration (between the stars) is inhibited at all orbital phases by the opposing star's radiation field, reducing pre-shock velocities below terminal velocities. To obtain good agreement with the X-ray observations, our initial mass-loss rate estimates require a down-shift by a factor of ˜7.7 to 6.5 × 10[SUP]-7[/SUP] M[SUB]⊙[/SUB] yr[SUP]-1[/SUP] and 7.5 × 10[SUP]-7[/SUP] M[SUB]⊙[/SUB] yr[SUP]-1[/SUP] for the primary and secondary star, respectively. Furthermore, the low gas densities and high shock velocities in Cyg OB2 #9 are suggestive of unequal electron and ion temperatures, and the X-ray analysis indicates that an immediately post-shock electron-ion temperature ratio of ≃0.1 is also required. The radio emission is dominated by non-thermal synchrotron emission. A parameter space exploration provides evidence against models assuming equipartition between magnetic and relativistic energy densities. However, fits of comparable quality can be attained with models having stark contrasts in the ratio of magnetic-to-relativistic energy densities. Both X-ray and radio lightcurves are largely insensitive to viewing angle. The variations in X-ray emission with orbital phase can be traced back to an inverse relation with binary separation and pre-shock velocity. The radio emission also scales with pre-shock velocity and binary separation, but to positive powers (i.e. not inversely). The radio models also reveal a subtle effect whereby inverse Compton cooling leads to an increase in emissivity as a result of the synchrotron characteristic frequency being significantly reduced. Finally, using the results of the radio analysis, we estimate the surface magnetic field strengths to be ≈0.3 - 52G. [less ▲]

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See detailSimulation and optimization of a CHP biomass plant and district heating network
Sartor, Kevin ULg; Quoilin, Sylvain ULg; Dewallef, Pierre ULg

in Applied Energy (2014), 130

Biomass Combined Heat and Power (CHP) plants connected to district heating (DH) networks are recognized nowadays as a very good opportunity to increase the share of renewable sources into energy systems ... [more ▼]

Biomass Combined Heat and Power (CHP) plants connected to district heating (DH) networks are recognized nowadays as a very good opportunity to increase the share of renewable sources into energy systems. However, as CHP plants are not optimized for electricity production, their operation is profitable only if a sufficient heat demand is available throughout the year. Most of the time, pre-feasibility studies are based on peak power demand and business plans only assume monthly or yearly consumption data. This approach usually turns out to overestimate the number of operating hours or oversize the plant capacity. This contribution presents a methodology intended to be simple and effective that provides accurate estimations of economical, environmental and energetic performances of CHP plants connected to district heating networks. A quasi-steady state simulation model of a CHP plant combined with a simulation model of the district heating network installed on the Campus of the University in Liège (Belgium) is used as an application framework to demonstrate the effectiveness of the selected approach. Based on the developed model and actual consumption data, several scenarios for energy savings are considered and ranked. The potential energy savings and resulting energy costs are estimated enabling more general conclusions to be drawn on the opportunity of using district heating networks in urban districts for Western Europe countries. [less ▲]

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See detailDynamic Simulation of Large-scale Power Systems Using a Parallel Schur-complement-based Decomposition Method
Aristidou, Petros ULg; Fabozzi, Davide; Van Cutsem, Thierry ULg

in IEEE Transactions on Parallel and Distributed Systems (2014), 25(10), 2561-2570

Power system dynamic simulations are crucial for the operation of electric power systems as they provide important information on the dynamic evolution of the system after an occurring disturbance. This ... [more ▼]

Power system dynamic simulations are crucial for the operation of electric power systems as they provide important information on the dynamic evolution of the system after an occurring disturbance. This paper proposes a robust, accurate and efficient parallel algorithm based on the Schur complement domain decomposition method. The algorithm provides numerical and computational acceleration of the procedure. Based on the shared-memory parallel programming model, a parallel implementation of the proposed algorithm is presented. The implementation is general, portable and scalable on inexpensive, shared-memory, multi-core machines. Two realistic test systems, a medium-scale and a large-scale, are used for performance evaluation of the proposed method. [less ▲]

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See detailUnveiling the effects of berenil, a DNA-binding drug, on Trypanosoma cruzi: implications for kDNA ultrastructure and replication.
Zuma, Aline Araujo; Cavalcanti, Danielle Pereira; Zogovich, Marcelo et al

in Parasitology research (2014)

Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits a single mitochondrion with an enlarged portion termed kinetoplast. This unique structure harbors the mitochondrial DNA (kDNA ... [more ▼]

Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits a single mitochondrion with an enlarged portion termed kinetoplast. This unique structure harbors the mitochondrial DNA (kDNA), composed of interlocked molecules: minicircles and maxicircles. kDNA is a hallmark of kinetoplastids and for this reason constitutes a valuable target in chemotherapeutic and cell biology studies. In the present work, we analyzed the effects of berenil, a minor-groove-binding agent that acts preferentially at the kDNA, thereby affecting cell proliferation, ultrastructure, and mitochondrial activity of T. cruzi epimastigote form. Our results showed that berenil promoted a reduction on parasite growth when high concentrations were used; however, cell viability was not affected. This compound caused significant changes in kDNA arrangement, including the appearance of membrane profiles in the network and electron-lucent areas in the kinetoplast matrix, but nuclear ultrastructure was not modified. The use of the TdT technique, which specifically labels DNA, conjugated to atomic force microscopy analysis indicates that berenil prevents the minicircle decatenation of the network, thus impairing DNA replication and culminating in the appearance of dyskinetoplastic cells. Alterations in the kinetoplast network may be associated with kDNA lesions, as suggested by the quantitative PCR (qPCR) technique. Furthermore, parasites treated with berenil presented higher levels of reactive oxygen species and a slight decrease in the mitochondrial membrane potential and oxygen consumption. Taken together, our results reveal that this DNA-binding drug mainly affects kDNA topology and replication, reinforcing the idea that the kinetoplast represents a potential target for chemotherapy against trypanosomatids. [less ▲]

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See detailData processing of vibrational chemical imaging for pharmaceutical applications.
Sacre, Pierre-Yves ULg; De Bleye, Charlotte ULg; Chavez, Pierre-François ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (2014), 101

Vibrational spectroscopy (MIR, NIR and Raman) based hyperspectral imaging is one of the most powerful tools analyze pharmaceutical preparation. Indeed, it combines the advantages of vibrational ... [more ▼]

Vibrational spectroscopy (MIR, NIR and Raman) based hyperspectral imaging is one of the most powerful tools analyze pharmaceutical preparation. Indeed, it combines the advantages of vibrational spectroscopy to imaging techniques and allows therefore the visualization of distribution of compounds, crystallization processes. However, these techniques provide a huge amount of data that must be processed to extract the relevant information. This review presents fundamental concepts of hyperspectral imaging, the basic theory of the most used chemometric tools used to pre-process, process and post-process the generated data. The last part of the present paper focuses on pharmaceutical applications of hyperspectral imaging and highlights the data processing approaches to enable the reader making the best choice among the different tools available. [less ▲]

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See detailSystematic analysis of site-specific yield distributions resulting from nitrogen management and climatic variability interactions
Dumont, Benjamin ULg; Basso, Bruno; Leemans, Vincent ULg et al

in Precision Agriculture (2014)

At the plot level, crop simulation models such as STICS have the potential to evaluate risk associated with management practices. In nitrogen (N) management, however, the decision-making process is ... [more ▼]

At the plot level, crop simulation models such as STICS have the potential to evaluate risk associated with management practices. In nitrogen (N) management, however, the decision-making process is complex because the decision has to be taken without any knowledge of future weather conditions. The objective of this paper is to present a general methodology for assessing yield variability linked to climatic uncertainty and variable N rate strategies. The STICS model was coupled with the LARS-Weather Generator. The Pearson system and coefficients were used to characterise the shape of yield distribution. Alternatives to classical statistical tests were proposed for assessing the normality of distributions and conducting comparisons (namely, the Jarque-Bera and Wilcoxon tests, respectively). Finally, the focus was put on the probability risk assessment, which remains a key point within the decision process. The simulation results showed that, based on current N application practice among Belgian farmers (60 60 60 kgN ha-1), yield distribution was very highly significantly non normal, with the highest degree of asymmetry characterised by a skewness value of -1.02. They showed that this strategy gave the greatest probability (60%) of achieving yields that were superior to the mean (10.5 t ha-1) of the distribution. [less ▲]

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See detailEccentric muscle contractions: risks and benefits
Hody, Stéphanie ULg; Croisier, Jean-Louis ULg; Lacrosse, Zoé ULg et al

in Proceedings of the Belgian Royal Academies of Medicine (2014)

La contraction musculaire excentrique se caractérise par le développement d'une tension musculaire associée à l'étirement concomitant du complexe musculo-tendineux. Ce mode de contraction présente un ... [more ▼]

La contraction musculaire excentrique se caractérise par le développement d'une tension musculaire associée à l'étirement concomitant du complexe musculo-tendineux. Ce mode de contraction présente un intérêt croissant dans de nombreux domaines tels que l’entraînement sportif, la médecine physique et la rééducation. De plus, certaines indications de l’entraînement en mode excentrique ont été posées chez des patients porteurs de maladies chroniques. Cependant, lorsqu’il est réalisé de manière intense et inhabituelle, l’exercice excentrique peut entraîner diverses altérations de l’ultrastructure musculaire qui se manifestent par une série de symptômes cliniques comme des douleurs musculaires d’apparition retardées (Delayed-Onset Muscle Soreness, DOMS) et une altération de la fonction musculaire. Malgré la littérature abondante consacrée à la description du phénomène des DOMS, aucune théorie cohérente n’est actuellement disponible pour expliquer la survenue différée des sensations douloureuses et des signes associés. De même, toujours à l’analyse de la littérature, on ne peut que constater l’absence de solution thérapeutique susceptible d’atténuer significativement l’intensité des DOMS et de leurs conséquences fonctionnelles associées à l’exception, paradoxalement, de l’exercice excentrique lui-même qui, lorsqu’il est proposé en conditions sous-maximales d’intensité progressivement croissante, semble constituer la seule prévention réellement efficace de l’apparition des DOMS. De même, si l’efficacité d’un entraînement spécifique dans la prévention des DOMS a été confirmée par de nombreux travaux, la nature de cet effet protecteur reste sujette à conjectures. Nous sommes néanmoins convaincus qu’une meilleure compréhension des réponses aiguës et/ou adaptatives à l’exercice excentrique contribuerait d’une part, à la mise au point d’interventions thérapeutiques efficaces et d’autre part, à élucider les évènements moléculaires impliqués dans des conditions pathologiques telles que les myalgies et certaines maladies neuromusculaires. [less ▲]

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See detailEvidence of oxidative stress and mitochondrial respiratory chain dysfunction in an in vitro model of sepsis-induced kidney injury
Quoilin, Caroline ULg; Mouithys-Mickalad, Ange ULg; Lécart, Sandrine et al

in Biochimica et Biophysica Acta-Bioenergetics (2014), 1837(10), 1790-1800

To investigate the role of oxidative stress and/or mitochondrial impairment in the occurrence of acute kidney injury (AKI) during sepsis, we developed a sepsis-induced in vitro model using proximal ... [more ▼]

To investigate the role of oxidative stress and/or mitochondrial impairment in the occurrence of acute kidney injury (AKI) during sepsis, we developed a sepsis-induced in vitro model using proximal tubular epithelial cells exposed to a bacterial endotoxin (lipopolysaccharide, LPS). This investigation has provided key features on the relationship between oxidative stress and mitochondrial respiratory chain activity defects. LPS treatment resulted in an increase in the expression of inducible nitric oxide synthase (iNOS) and NADPH oxidase 4 (NOX-4), suggesting the cytosolic overexpression of nitric oxide and superoxide anion, the primary reactive nitrogen species (RNS) and reactive oxygen species (ROS). This oxidant state seemed to interrupt mitochondrial oxidative phosphorylation by reducing cytochrome c oxidase activity. As a consequence, disruptions in the electron transport and the proton pumping across the mitochondrial inner membrane occurred, leading to a decrease of the mitochondrial membrane potential, a release of apoptotic-inducing factors and a depletion of adenosine triphosphate. Interestingly, after being targeted by RNS and ROS, mitochondria became in turn producer of ROS, thus contributing to increase the mitochondrial dysfunction. The role of oxidants in mitochondrial dysfunction was further confirmed by the use of iNOS inhibitors or antioxidants that preserve cytochrome c oxidase activity and prevent mitochondrial membrane potential dissipation. These results suggest that sepsis-induced AKI should not only be regarded as failure of energy status but also as an integrated response, including transcriptional events, ROS signaling, mitochondrial activity and metabolic orientation such as apoptosis. [less ▲]

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See detailL’ANATOMIE REVISITÉE DU PETIT BASSIN
Bonnet, Pierre ULg

in Louvain Medical (2014), 133(8), 3-13

Le petit bassin est un espace cônique musculoosseux comportant la portion inférieure de la cavité péritonéale surmontant l’espace endopelvien. Les viscères pelviens reçoivent leur vascularisation des ... [more ▼]

Le petit bassin est un espace cônique musculoosseux comportant la portion inférieure de la cavité péritonéale surmontant l’espace endopelvien. Les viscères pelviens reçoivent leur vascularisation des parois latérales au sein de l’espace endopelvien, leur innervation dépend d’une double origine, abdominale et pelvienne. Les parois de cet espace abritent les nerfs somatiques et vaisseaux destinés aux parois de la partie inférieure du tronc et aux membres inférieurs. La connaissance pratique de cette anatomie peut être aidée par une approche constructive élaborant les parois et ensuite le contenu de cet espace. [less ▲]

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