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See detailDNA polymorphism detection in Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae): potential use in stored product pest management
Braet, Yves; Haubruge, Eric ULg

in DNA Sequence : The Journal of DNA Sequencing & Mapping (1995), 6

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See detailThermographie routière nocturne de la Région Wallonne : méthodologie, présentation des résultats et intérêts de l'approche topoclimatologique
Funcken, Ph.; Erpicum, Michel ULg; Frédéric, Marc ULg et al

in Publications de l'Association Internationale de Climatologie (1995), 8

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See detailJ. Peneff : l'hôpital en urgence
Melard, François ULg

in Recherches sociologiques (1995), 1

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See detailTemperature dependence of chlorophyll(ide) spectral shifts and photoactive protochlorophyllide regeneration after flash in etiolated barley leaves
Eullaffroy; Salvetat; Franck, Fabrice ULg et al

in Photochemistry & Photobiology (1995), 62(4), 751-756

Absorbance spectroscopy at 77 K was used to investigate the effect of temperature on in vivo chlorophyllide shifts and photoactive protochlorophyllide regeneration after a saturating flash, which ... [more ▼]

Absorbance spectroscopy at 77 K was used to investigate the effect of temperature on in vivo chlorophyllide shifts and photoactive protochlorophyllide regeneration after a saturating flash, which transformed all protochlorophyllide to chorophyllide. Photoactive protochlorophyllide present in darkness was stable up to 40 degrees C. The rate of Shibata shift and protochlorophyllide regeneration after flash were strongly temperature dependent in the range 0-25 degrees C. At 0 degrees C, the shift was still observed but no regeneration occurred. Only slight effects were observed in the range 25-40 degrees C. At all temperatures, the process of protochlorophyllide regeneration was significantly slower than the Shibata shift. The final chlorophyll shift from 672 to 674 nm was observed up to 40 degrees C. The implication of these results concerning the pigment-protein interactions during the Shibata shift are discussed. [less ▲]

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See detailAcetic acid esters synthesis catalysed by Candida antarctica lipase.
Fonteyn, Fabienne ULg; Lognay, Georges ULg; Marlier, M.

in Bulletin des Recherches Agronomiques de Gembloux (1995), 30(3), 183-188

Synthesis of various acetates catalysed by the Candida antarctica SP435 lipase was carried out in n-heptane. Reactions progress was established over a one hour period. Differences appeared in function of ... [more ▼]

Synthesis of various acetates catalysed by the Candida antarctica SP435 lipase was carried out in n-heptane. Reactions progress was established over a one hour period. Differences appeared in function of the structure and the chain length of alcohols: linalool and menthol were not esterified whereas the esterification of 1-dodecanol gave the highest rate (474 micromole per min and per g) and yield (86 per cent). [less ▲]

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See detailIron chelation decreases NF-kappaB and HIV-1 activation due to oxidative stress
Sappey, Christine; Boelaert, J. R.; Legrand-Poels, Sylvie ULg et al

in AIDS Research and Human Retroviruses (1995)

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See detailRat embryo fibroblasts immortalization by bovine leukemia virus Tax protein
Willems, Luc ULg; Heremans, H.; Burny, A. et al

in Methods in Cell Science : An Official Journal of the Society for in Vitro Biology (1995)

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See detailAntihyperglycaemic agents. Drug interactions of clinical importance.
Scheen, André ULg; Lefebvre, Pierre ULg

in Drug Safety : An International Journal of Medical Toxicology & Drug Experience (1995), 12(1), 32-45

Non-insulin-dependent (type 2) diabetes mellitus (NIDDM) affects middle-aged or elderly people who frequently have several other concomitant diseases, especially obesity, hypertension, dyslipidaemias ... [more ▼]

Non-insulin-dependent (type 2) diabetes mellitus (NIDDM) affects middle-aged or elderly people who frequently have several other concomitant diseases, especially obesity, hypertension, dyslipidaemias, coronary insufficiency, heart failure and arthropathies. Thus, polymedication is the rule in this population, and the risk of drug interactions is important, particularly in elderly patients. The present review is restricted to the interactions of other drugs with antihyperglycaemic compounds, and will not consider the mirror image, i.e. the interactions of antihyperglycaemic agents with other drugs. Oral antihyperglycaemic agents include sulphonylureas, biguanides--essentially metformin since the withdrawn of phenformin and buformin--and alpha-glucosidase inhibitors, acarbose being the only representative on the market. These drugs can be used alone or in combination to obtain better metabolic control, sometimes with insulin. Drug interactions with antihyperglycaemic agents can be divided into pharmacokinetic and pharmacodynamic interactions. Most pharmacokinetic studies concern sulphonylureas, whose action may be enhanced by numerous other drugs, thus increasing the risk of hypoglycaemia. Such an effect may result essentially from protein binding displacement, inhibition of hepatic metabolism and reduction of renal clearance. Reduction of the hypoglycaemic activity of sulphonylureas due to pharmacokinetic interactions with other drugs appears to be much less frequent. Drug interactions leading to an increase in plasma metformin concentrations, mainly by reducing the renal excretion or the hepatic metabolism of the biguanide, should be avoided to limit the risk of hyperlactaemia. Owing to its mode of action, pharmacokinetic interferences with acarbose are limited to the gastrointestinal tract, but have not been extensively studied yet. Pharmacodynamic interactions are quite numerous and may result in a potentiation of the hypoglycaemic action or, conversely, in a deterioration of blood glucose control. Such interactions may be observed whatever the type of antidiabetic treatment. They result from the intrinsic properties of the coprescribed drug on insulin secretion and action, or on a key step of carbohydrate metabolism. Finally, a combination of 2 to 3 antihyperglycaemic agents is common for treating patients with NIDDM to benefit from the synergistic effect of compounds acting on different sites of carbohydrate metabolism. Possible pharmacokinetic interactions between alpha-glucosidase inhibitors and classical antidiabetic oral agents should be better studied in the diabetic population. [less ▲]

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See detailÉvolution technique au Paléolithique ancien de Karain (Turquie)
Otte, Marcel ULg; Yalçinkaya, Isin; Kozlowski, Janusz et al

in Anthropologie (L') (1995), 99(4), 529-561

The Karain Cave, in Southern Turkey, provided a long sequence pf Lower and Middle Palaeoliothic. A "Clactonian" type flake industry is present at the basis, with numerous denticulates and notches. The ... [more ▼]

The Karain Cave, in Southern Turkey, provided a long sequence pf Lower and Middle Palaeoliothic. A "Clactonian" type flake industry is present at the basis, with numerous denticulates and notches. The evolution is marked by the development of the elaborated preparation of flakes leading to the Levallois technology. Four climatic cycles were recognized, each with an alternance of a long cold phase and thinner tempered deposits. The now available radiometric datations place the last tempered phase around 120 to 100,000 years. [less ▲]

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See detailPhysical Properties of Particles of Ipratropium and Clenbuterol Generated by Equipment Suitable for the Inhalation of Drugs by Calves
Genicot, Bruno; Lapp, K.; Close, Roland et al

in Research in Veterinary Science (1995), 59(2), 164-167

When solutions of ipratropium and clenbuterol were atomised at 300 kPa and 450 kPa in equipment suitable for the inhalation of drugs by calves, the numbers, velocities and diameters of the particles ... [more ▼]

When solutions of ipratropium and clenbuterol were atomised at 300 kPa and 450 kPa in equipment suitable for the inhalation of drugs by calves, the numbers, velocities and diameters of the particles produced were similar. When the pressure was increased to 600 kPa more of the particles were less than 2 microns in diameter and fewer were more than 7 microns in diameter, the fractions of the total mass of the solution generated in these size ranges were similarly increased and decreased, and the velocities of the particles were increased. At any given pressure, the numbers of particles of different sizes, and the proportions of the total mass generated, were similar for the solutions of ipratropium and clenbuterol, but a solution of saline produced more particles with a diameter less than 3 microns. Particles from the solution of ipratropium had the highest velocity and particles from the solution of clenbuterol had the lowest velocity. [less ▲]

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See detailGlucose metabolism in obese subjects: lessons from OGTT, IVGTT and clamp studies.
Scheen, André ULg; Paquot, Nicolas ULg; Letiexhe, Michel ULg et al

in International Journal of Obesity & Related Metabolic Disorders (1995), 19 Suppl 3

Impaired glucose tolerance and overt diabetes are more frequent in presence than in absence of obesity. In obese subjects, glucose tolerance can be maintained within the normal range by compensating for ... [more ▼]

Impaired glucose tolerance and overt diabetes are more frequent in presence than in absence of obesity. In obese subjects, glucose tolerance can be maintained within the normal range by compensating for insulin resistance by peripheral hyperinsulinism, the latter resulting from both increased insulin secretion and reduced insulin clearance. Impaired glucose tolerance is observed when insulin resistance is associated to impaired first-phase insulin response, which results in a significant increase in plasma glucose levels and a late insulin hyperresponsiveness. Both hyperinsulinaemia and hyperglycaemia are then able to overcome peripheral insulin resistance and impaired glucose disposal. When a more marked defect in insulin secretion is present, hyperglycaemia progresses, probably due to an additional participation of impaired suppression of hepatic glucose output. Overt diabetes then occurs with persistent post-absorptive hyperglycaemia. All these abnormalities can be reversed after a marked weight loss and recovery of ideal body weight, arguing for acquired rather than inherited metabolic defects in presence of morbid obesity. If a sufficient weight reduction can not be obtained, pharmacological approaches may be considered to improve insulin resistance of obese subjects, especially those with impaired glucose tolerance or overt diabetes. [less ▲]

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See detailBreakdown of the stereospecificity of DD-peptidases and beta-lactamases with thiolester substrates.
Damblon, Christian ULg; Zhao, G. H.; Jamin, M. et al

in Biochemical Journal (1995), 309 ( Pt 2)

With peptide analogues of their natural substrates (the glycopeptide units of nascent peptidoglycan), the DD-peptidases exhibit a strict preference for D-Ala-D-Xaa C-termini. Gly is tolerated as the C ... [more ▼]

With peptide analogues of their natural substrates (the glycopeptide units of nascent peptidoglycan), the DD-peptidases exhibit a strict preference for D-Ala-D-Xaa C-termini. Gly is tolerated as the C-terminal residue, but with a significantly decreased activity. These enzymes were also known to hydrolyse various ester and thiolester analogues of their natural substrates. Some thiolesters with a C-terminal leaving group that exhibited L stereochemistry were significantly hydrolysed by some of the enzymes, particularly the Actinomadura R39 DD-peptidase, but the strict specificity for a D residue in the penultimate position was fully retained. These esters and thiolesters also behave as substrates for beta-lactamases. In this case, thiolesters exhibiting L stereochemistry in the ultimate position could also be hydrolysed, mainly by the class-C and class-D enzymes. However, more surprisingly, the class-C Enterobacter cloacae P99 beta-lactamase also hydrolysed thiolesters containing an L residue in the penultimate position, sometimes with a higher efficiency than the D isomer. [less ▲]

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See detailEffects of infused sodium lactate on glucose and energy metabolism in healthy humans.
Paquot, Nicolas ULg; Schneiter, P.; Cayeux, M. C. et al

in Diabètes & Métabolism (1995), 21(5), 345-52

To assess the effects of lactate on glucose metabolism, sodium lactate (20 mumol.kg-1.min-1) was infused into healthy subjects in basal conditions and during application of a hyperinsulinaemic (6 pmol.kg ... [more ▼]

To assess the effects of lactate on glucose metabolism, sodium lactate (20 mumol.kg-1.min-1) was infused into healthy subjects in basal conditions and during application of a hyperinsulinaemic (6 pmol.kg-1.min-1) euglycaemic clamp. Glucose rate of appearance (GRa) and disappearance (GRd) were measured from plasma dilution of infused U- 13C glucose, and glucose oxidation (G(ox)) from breath 13CO2 and plasma 13C glucose. In basal conditions, lactate infusion did not alter G(ox) (8.8 +/- 0.9 vs 9.2 +/- 1.1 mumol.kg-1.min-1), while GRa slightly decreased from 15.2 +/- 0.8 basal to 13.9 +/- 0.9 mumol.kg-1.min-1 after lactate (p < 0.05). During a hyperinsulinaemic clamp, hepatic glucose production was completely suppressed with or without lactate. Lactate decreased G(ox) from 17.1 +/- 0.4 to 13.4 +/- 1.2 mumol.kg-1.min-1 (p < 0.05), whereas GRd was unchanged (39.7 +/- 3.6 vs 45.6 +/- 2.6 mumol.kg-1.min-1. It is concluded that infusion of lactate in basal conditions does not increase GRa or interfere with peripheral glucose oxidation, and that during hyperinsulinaemia lactate decreases glucose oxidation but does not alter hepatic or peripheral insulin sensitivity. [less ▲]

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See detailUnaudited clinical experience.
NISOLLE, Michelle ULg; Donnez, Jacques

in Fertility and Sterility (1995), 63(4), 934-5

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See detailLa climatologie comme facteur modifiant du projet urbain
Dupagne, Albert ULg; Leclercq, Pierre ULg

in Publications de l'Association Internationale de Climatologie (1995), 8

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See detailDélimitation des hinterlands des agglomérations urbaines au départ d’une image de télédétection
Donnay, Jean-Paul ULg

in Revue Belge de Géographie (1995), 3-4(59), 325-331

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See detailDe ruimtebeleving in Vestdijks Verzamelde verhalen III
Nachtergaele, Lutgarde ULg

in Vestdijkkroniek (1995), 88-89

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See detailProtective Effect of Various Antagonists of Inflammatory Mediators against Paraoxon-Induced Pulmonary Edema in the Rabbit
Delaunois, Annie ULg; Gustin, Pascal ULg; Vargas, M. et al

in Toxicology and Applied Pharmacology (1995), 132(2), 343-345

The protective effect of some antagonists of various inflammatory mediators against paraoxon-induced increases in endothelial permeability has been investigated in isolated perfused rabbit lungs. The ... [more ▼]

The protective effect of some antagonists of various inflammatory mediators against paraoxon-induced increases in endothelial permeability has been investigated in isolated perfused rabbit lungs. The edema induced by paraoxon has been previously related to a chain reaction mediated by acetylcholine. Lungs were ventilated and blood-free perfused with a constant flow. Arterial and venous pressures and lung weight were continuously recorded. Endothelial permeability was evaluated by measuring the capillary filtration coefficient (Kf,c). Paraoxon (4 x 10(-4) M) was injected in the perfusion circuit, in lungs with or without pretreatment with atropine, ketanserin, clonidine, morphine, indomethacin, and terfenadine plus cimetidine. Paraoxon induced a time-dependent increase in the Kf,c, a maximal effect being recorded 60 min after the injection. All the antagonists used as pretreatment significantly reduced the maximal effect recorded after paraoxon. These results show that muscarinic receptor antagonists, inhibitors of neuropeptides release, cyclooxygenase inhibitors, and 5-hydroxytryptamine and histamine receptor antagonists can protect the lung against the edema induced by paraoxon. This protective effect is due to inhibition of the chain reaction triggered by acetylcholine. [less ▲]

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See detailComposition n'est pas raison? Une contrefaçon liégeoise de la Théorie de l'impôt de Mirabeau (1761)
Droixhe, Daniel ULg

in De Gulden Passer = Le compas d'or (1995), 73

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See detailForbidden transitions of Astrophysical Interest in the 5pk (k=1-5) Configurations
Biémont, Emile ULg; Hansen, J. E.; Quinet, Pascal ULg et al

in Astronomy and Astrophysics. Supplement Series (1995), 111

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See detailFinite-amplitude regimes of the short-wave Marangoni-Benard convective instability.
Colinet, Pierre; Legros, Jean-Claude; Kamotani, Y. et al

in Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (1995), 52(3), 2603-2616

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See detailThe Anatolian Middle Palaeolithic. New Research at Karain Cave
Otte, Marcel ULg; Yalçinkaya, Isin; Taskiran, Harun et al

in Journal of Anthropological Research (1995), 51(4), 287-299

The aims of this report are three-fold: i. to provide new informattion concerning the Palaeolithic of Turkey; ii. to present the shifts in lithic techniques évidenced during this period; and iii. to ... [more ▼]

The aims of this report are three-fold: i. to provide new informattion concerning the Palaeolithic of Turkey; ii. to present the shifts in lithic techniques évidenced during this period; and iii. to demonstrate significance of the new information for interpreting long distance relations between Western Asia and Europe. In fact, in spite of the crucial geographic situation of Anatolia between the Near East and Europe, it has rarely been the subject of intensive excavations and publications concerning the Paleolithic periods. Recently obtained data are therefore of significant interest. [less ▲]

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See detailDeux chansons relatives à des imprimeries liégeoises du XVIIIe siècle
Droixhe, Daniel ULg

in Bulletin de la Société Royale Le Vieux-Liège (1995), 268

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See detailThiamine Deficiency--Induced Partial Necrosis and Mitochondrial Uncoupling in Neuroblastoma Cells Are Rapidly Reversed by Addition of Thiamine
Bettendorff, Lucien ULg; Sluse, Francis ULg; Goessens, Guy ULg et al

in Journal of Neurochemistry (1995), 65(5), 2178-2184

Culture of neuroblastoma cells in a medium of low-thiamine concentration (6 nM) and in the presence of the transport inhibitor amprolium leads to the appearance of overt signs of necrosis; i.e., the ... [more ▼]

Culture of neuroblastoma cells in a medium of low-thiamine concentration (6 nM) and in the presence of the transport inhibitor amprolium leads to the appearance of overt signs of necrosis; i.e., the chromatin condenses in dark patches, the oxygen consumption decreases, mitochondria are uncoupled, and their cristae are disorganized. Glutamate formed from glutamine is no longer oxidized and accumulates, suggesting that the thiamine diphosphate-dependent alpha-ketoglutarate dehydrogenase activity is impaired. When thiamine (10 microM) is added to the cells, the O2 consumption increases, respiratory control is restored, and normal cell and mitochondrial morphology is recovered within 1 h. Succinate, which is oxidized via the thiamine diphosphate-independent succinate dehydrogenase, is also able to restore a normal O2 consumption (with respiratory control) in digitonin-permeabilized thiamine-deficient cells. Our results therefore suggest that the slowing of the citric acid cycle is the main cause of the biochemical lesion induced by thiamine deficiency as observed in Wernicke's encephalopathy. [less ▲]

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See detailAcquis de la recherche en matière d'évaluation génétique des ovins et des caprins en Tunisie
D'Jemali, M'naouer; Jamal, Sofiene; Ben-Dhiaf, Sonia et al

in Cahiers Options Méditerranéennes (1995), 11

Work carried out on performance recording for growth and milk yield in sheep and goats for use in genetic evaluation is briefly summarized, and preliminary data on the growth and reproductive traits of 9 ... [more ▼]

Work carried out on performance recording for growth and milk yield in sheep and goats for use in genetic evaluation is briefly summarized, and preliminary data on the growth and reproductive traits of 9 flocks of Barbary sheep in 1987-92 are presented in 14 tables and discussed. [less ▲]

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See detailThiamine Homeostasis in Neuroblastoma Cells
Bettendorff, Lucien ULg

in Neurochemistry International (1995), 26(3), 295-302

We recently showed that thiamine uptake by neuroblastoma cells is mediated by two saturable transport system: the first with high affinity for thiamine (Km = 35 nM) is blocked by veratridine; the other ... [more ▼]

We recently showed that thiamine uptake by neuroblastoma cells is mediated by two saturable transport system: the first with high affinity for thiamine (Km = 35 nM) is blocked by veratridine; the other, with low affinity is blocked by Ca2+. The driving force for thiamine uptake is its phosphorylation to thiamine diphosphate (TDP) by thiamine pyrophosphokinase and subsequent binding of this cofactor to apoenzymes. Our results suggest that cells of neuronal origin possess mechanisms regulating the intracellular concentration of thiamine. At low external thiamine, the vitamin is taken up by a high-affinity transporter and pyrophosphorylated in thiamine diphosphate (TDP): this is the TDP pool of slow turnover. An intraover extracellular concentration gradient of free thiamine is observed at low external concentration of the vitamin. At higher external thiamine concentration, TDP accumulation is limited by the binding capacity to the apoenzymes and unbound TDP (i.e. a small pool of fast turnover) is quickly hydrolyzed. Thiamine is slowly released by the cells by at least two different mechanisms. The first, accounting for a maximum of 50% of total thiamine release, is stimulated by external thiamine and is blocked by veratridine, suggesting that it is a self-exchange mechanism catalyzed by the high affinity thiamine transporter. The remaining thiamine efflux is neither sensitive to veratridine nor to Ca2+ and its mechanism is unknown. About 25% of intracellular thiamine is not released, even after treatment of the cells with digitonin, thus maintaining an apparent gradient. This suggests a binding or sequestration in intracellular compartments.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailInteresting Lines in the Infrared Solar Spectrum. II. Unblended Lines between 1.0 and 1.8µm
Ramsauer, J.; Solanki, S. K.; Biémont, Emile ULg

in Astronomy and Astrophysics. Supplement Series (1995), 113

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See detailInhibition of growth of normal and human papillomavirus-transformed keratinocytes in monolayer and organotypic cultures by interferon-gamma and tumor necrosis factor-alpha.
Delvenne, Philippe ULg; al-Saleh, W.; Gilles, Christine ULg et al

in American Journal of Pathology (1995), 146(3), 589-98

The growth response of normal and human papillomavirus (HPV)-transformed cervical keratinocytes to interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha was investigated in monolayer and ... [more ▼]

The growth response of normal and human papillomavirus (HPV)-transformed cervical keratinocytes to interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha was investigated in monolayer and organotypic raft cultures. The proliferation rates of monolayer cultures were assessed by [3H]TdR incorporation and fluorimetric DNA titration. The growth of keratinocytes in organotypic cultures was estimated by their ability to stratify on collagen rafts and by immunohistochemistry for Ki67 antigen expression. IFN-gamma reduced the DNA synthesis of normal and HPV-transformed keratinocytes in monolayer cultures and exerted a marked growth inhibitory effect in organotypic raft cultures. In control raft cultures, normal keratinocytes produced an epithelial sheet of approximately 10 cells in thickness that closely resembled normal cervical epithelium and was characterized by sparse Ki67 antigen-positive cells whereas HPV-transformed keratinocytes produced up to 15 poorly differentiated epithelial layers that were reminiscent of high grade cervical lesions seen in vivo and exhibited a full thickness Ki67 antigen expression. When normal and HPV-transformed keratinocytes were maintained in the presence of IFN-gamma, the epithelial sheet was reduced to a few cells in thickness and the density of Ki67 antigen-positive cells was decreased. A more pronounced growth inhibitory effect in monolayer and organotypic cultures was observed when IFN-gamma was associated with tumor necrosis factor-alpha Tumor necrosis factor-alpha alone reduced the DNA synthesis of normal keratinocytes but was significantly less effective than IFN-gamma to inhibit the growth of HPV-transformed keratinocytes. These results suggest that similar responses in vivo to regulatory molecules may play a role in the development of HPV-related lesions. [less ▲]

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See detailVaricella-zoster virus induces apoptosis in cell culture
Sadzot-Delvaux, Catherine ULg; Thonard, P.; Schoonbroodt, Sonia et al

in Journal of General Virology (The) (1995), 76(Pt 11), 2875-2879

Apoptosis is an active mechanism of cell death which can be initiated in response to various stimuli including virus infections. In this work, we demonstrate that lytic infection by varicella-zoster virus ... [more ▼]

Apoptosis is an active mechanism of cell death which can be initiated in response to various stimuli including virus infections. In this work, we demonstrate that lytic infection by varicella-zoster virus (VZV), a human herpesvirus, is characterized by nuclear fragmentation of DNA into oligonucleosomal fragments and by chromatin condensation. In vitro, VZV-induced cell death is actually mediated by apoptosis. The mechanisms developed by cells to protect themselves against apoptosis could be one of the parameters allowing the establishment of virus latency. In the case of VZV, which can remain latent in sensory ganglia, we have not yet identified a cellular or viral protein which could play this protective role, since the observed apoptosis mechanism seems to be independent from Bcl-2, the most frequently described inhibitor of apoptosis. [less ▲]

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See detailComparative double-blind multicenter study of the efficacy of tiludronate and etidronate in Paget's disease of bone
Roux, C; Gennari, C; Farrerons, J et al

in BONE (1995), 16(S1), 503

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See detailEtiologie et physiopathologie du diabète de type 2.
SCHEEN, André ULg; PAQUOT, Nicolas ULg; Lefevre, P.

in Problèmes Actuels d'Endocrinologie et de Nutrition (1995), 10

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See detailL'hyperthyroïdie sévère associée à la prise d'amodarone: une urgence chirurgicale
Meurisse, Michel ULg; Hamoir, Etienne ULg; Joris, Jean ULg et al

in Revue Française d'Endocrinologie Clinique, Nutrition, et Métabolisme (La) (1995), 36(1), 35-45

L'évolution de certaines thyréotoxicoses associées à la prise d'amiodarone peut être particulièrement grave et rapide, menaçant le pronostic vital. De déclenchement brutal, sans relation avec la durée du ... [more ▼]

L'évolution de certaines thyréotoxicoses associées à la prise d'amiodarone peut être particulièrement grave et rapide, menaçant le pronostic vital. De déclenchement brutal, sans relation avec la durée du traitement par amiodarone, elles peuvent survenir aussi bien chez des sujets porteurs de thyroïdopathies méconnues ou négligées au moment de l'induction du traitement, que chez des patients apparemment indemnes de toute pathologie thyroïdienne pré-existante. Le traitement médical conservateur est le plus souvent inefficace. Dans ces cas, il convient de poser sans hésitation, l'indication d'une thyroïdectomie la plus radicale possible. Ce rapport traite de l'évolution post-opératoire spectaculaire et favorable de 13 cas consécutifs de thyréotoxicose sévère associée à la prise d'amiodarone. La validité de l'approche chirurgicale repose sur la correction rapide et définitive de l'état toxique après exérèse glandulaire. La morbidité quasi nulle liée au geste chirurgical est la seule alternative thérapeutique antithyroïdienne existante qui permette de poursuivre un traitement par amiodarone lorsque celui-ci est indiqué pour contrôler une arytmie menaçante [less ▲]

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See detailVaricella-zoster virus gene regulation
Piette, Jacques ULg; Defechereux, Patricia; Baudoux, Laurence et al

in Neurology (1995), 45(12, suppl. 8), 23-27

The varicella-zoster virus genome contains 71 open reading frames (ORFs), five of which (ORF62, ORF4, ORF63, ORF61, and ORF10) encode regulatory proteins. ORF62 codes for the major immediate early protein ... [more ▼]

The varicella-zoster virus genome contains 71 open reading frames (ORFs), five of which (ORF62, ORF4, ORF63, ORF61, and ORF10) encode regulatory proteins. ORF62 codes for the major immediate early protein of the virus exhibiting DNA-binding and regulatory functions. This protein, localized in the cell nucleus, is a functional homologue to ICP4 of herpes simplex virus type 1 (HSV-1). It trans-activates several varicella-zoster virus promoters of the various gene classes and autoregulates its own expression. ORF4 protein activates gene promoters provided they have basal activities, but it is not a functional homologue of HSV-1 ICP27. Gene regulation activity appears to be linked to its cysteine-rich C-terminal region. ORF63 codes for an immediate early protein mainly located in the cell nucleus. The regulatory functions it performs are still unclear. ORF61 protein is the functional homologue of HSV-1 ICPO. Its N-terminal region exhibits a RING domain responsible for trans-activating and trans-repressing activities. ORF10 protein exhibits similarities with HSV-1 VP16 and activates the ORF62 promoter. [less ▲]

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See detailAspects hémodynamiques de l'insulinorésistance: des concepts théoriques à la thérapeutique.
Paquot, Nicolas ULg; SCHEEN, André ULg; Lefebvre, P.

in Médecine et Hygiène (1995), 53

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See detailSurface Molecular Structure of Self-Assembled Alkanethiols Evidenced by UPS, Synchrotron Radiation and HREELS
Duwez, Anne-Sophie ULg; Riga, Joseph; ghijsen, Jacques et al

in Journal of Electron Spectroscopy & Related Phenomena (1995), 76

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See detailProposition Of A 3-Dimensional Representation Of The Constitutive Protein Of The Hepatitis-B Surface-Antigen Particles
Sonveaux, N.; Ruysschaert, Jm.; Brasseur, Robert ULg

in Journal of Protein Chemistry (1995), 14(6), 477-86

Hepatitis B surface antigen particles are composed of the major viral envelope protein, the S protein, embedded into a lipid shell. The description of the folding of this protein within the particle ... [more ▼]

Hepatitis B surface antigen particles are composed of the major viral envelope protein, the S protein, embedded into a lipid shell. The description of the folding of this protein within the particle membrane could provide helpful information for replacing surface-exposed protein domains by foreign sequences without destabilizing the particle structure. Since the crystallization of the protein in its lipid environment remains inaccessible in the near future, alternative approaches had to be envisaged. We combine here the available experimental structural and topological data with a conformational procedure to identify membrane-associated domains of the HBsAg protein and to propose a three-dimensional description of their assembly within the particle membrane. The proposed protein structure is composed of four membrane-spanning helices and an amphipatic helix located on the inner surface membrane. The transmembrane helices are assembled into a highly hydrophobic complex in which no access to the water environment is allowed. The approach could be extended to other membrane-associated proteins. [less ▲]

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See detailDifferential effects of drawing and indirect dopamine agonists on the induction of gnawing in C57BI/6J mice
Tirelli, Ezio ULg; Witkin, J. M.

in Journal of Pharmacology and Experimental Therapeutics (The) (1995), 273(1), 7-15

Compared the ability of indirect dopamine (DA) agonists to induce gnawing behavior (GB) in male C57BL/6J mice with that of direct DA agonists acting at DA D-sub-1 or D-sub-2 receptor subtypes. Eight Ss ... [more ▼]

Compared the ability of indirect dopamine (DA) agonists to induce gnawing behavior (GB) in male C57BL/6J mice with that of direct DA agonists acting at DA D-sub-1 or D-sub-2 receptor subtypes. Eight Ss were used per dose. Holes left by Ss on corrugations of packing cardboard were used as an objective index of GB. Indirect DA agonists, including DA releasers such as fencamfamine and amfonelic acid and DA uptake inhibitors such as cocaine and nomifensine, produced dose-dependent increases in GB. None of the direct agonists (e.g., apomorphine, quinpirole) increased GB. The dopaminergic nature of GB was confirmed in studies in which a host of compounds (e.g., nicotine, caffeine, dizocilpine) with primary actions at nondopaminergic sites did not induce GB. Given the general contrast between the effects of direct and indirect DA agonists, this procedure could serve as a rapid in vivo method of distinguishing direct- from indirect-acting DA agonists. ((c) 1997 APA/PsycINFO, all rights reserved) [less ▲]

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See detailAccroissement des exportations agricoles et sécurité alimentaire au Viêt-nam
Lebailly, Philippe ULg; Burny, Philippe ULg

in Economies et sociétés. Série Développement agro-alimentaire, A.G. (1995), 22(3-4), 361-371

La rénovation des politiques et des méthodes d'action à l'égard de l'agriculture a permis au Viêt-nam de conforter sa position de troisième exportateur mondial de riz. Néanmoins la situation semble moins ... [more ▼]

La rénovation des politiques et des méthodes d'action à l'égard de l'agriculture a permis au Viêt-nam de conforter sa position de troisième exportateur mondial de riz. Néanmoins la situation semble moins favorable qu'il n'y paraît. Le marché international du riz est caractérisé par des prix bas et par une forte concurrence entre pays exportateurs. En outre, le marché est réduit et instable. Il s'ensuit que le Viêt-nam, proche de l'autosuffisance, peut tantôt être importateur tantôt exportateur de riz selon les performances enregistrées par les riziculteurs. Cet article analyse les perspectives qui sont actuellement offertes au Viêt-nam en matière de sécurité alimentaire en relation avec l'adoption d'une politique agricole qui encourage l'accroissement des exportations de riz. [less ▲]

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See detailModulation of the Expression of Interstitial and Type-Iv Collagenases in Coculture of Ht1080 Fibrosarcoma Cells and Fibroblasts
Munaut, Carine ULg; Noël, Agnès ULg; Weidle, U. H. et al

in Invasion & Metastasis (1995), 15(5-6), 169-78

Members of the metalloproteinase family (MMPs) are known to play a crucial role in the metastatic cascade. Here, we report some investigations about the synthesis of interstitial and type-IV collagenases ... [more ▼]

Members of the metalloproteinase family (MMPs) are known to play a crucial role in the metastatic cascade. Here, we report some investigations about the synthesis of interstitial and type-IV collagenases (gelatinases A and B) in a model of coculture of human fibroblasts and HT 1080 fibrosarcoma cells. The interstitial collagenase activity, mainly found in the conditioned medium of fibroblasts, and its mRNA level were increased in the in vitro coculture model. In contrast, gelatinase A was produced by both cell types. The HT 1080 cells additionally synthesised gelatinase B. In coculture, an enhancement of gelatinase A and the presence of its activated form were observed. Northern blot analysis demonstrated that this enzymatic enhancement occurred at a pretranslational level. The stimulation of the interstitial collagenase activity was partially mediated through soluble factor(s), whereas increased gelatinase A appeared to require direct cell-cell interactions. The extracellular matrix component, type-I collagen, stimulated the enzymatic activities released by the individual cells, but it did not modulate the synthesis of interstitial collagenase in coculture. Our results demonstrate that distinct MMPs are modulated by distinct mechanisms, all depending on specific interactions between tumour cells and host fibroblasts. [less ▲]

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See detailShort administration of metformin improves insulin sensitivity in android obese subjects with impaired glucose tolerance.
Scheen, André ULg; Letiexhe, Michel ULg; Lefebvre, Pierre ULg

in Diabetic Medicine : A Journal of the British Diabetic Association (1995), 12(11), 985-9

In a double-blind, randomized, cross-over study, the metabolic effects of a short treatment with metformin (2 x 850 mg day-1 for 2 days and 850 mg 1 h before evaluation) were compared to those of placebo ... [more ▼]

In a double-blind, randomized, cross-over study, the metabolic effects of a short treatment with metformin (2 x 850 mg day-1 for 2 days and 850 mg 1 h before evaluation) were compared to those of placebo in 15 obese subjects (BMI: 33.2 +/- 0.9 kg m-2), with abdominal distribution of adipose tissue and impaired glucose tolerance. An intravenous glucose tolerance test (0.3 g glucose kg-1) was performed after each period of treatment. Areas under the curve (AUC0-180 min) were calculated for plasma glucose, insulin, and C-peptide levels. Glucose tolerance was estimated by the coefficient of glucose assimilation (KG). Insulin sensitivity (SI) and glucose effectiveness (SG) indices were calculated using Bergman's minimal model. Insulin secretion rate (ISR) was determined by deconvolution of plasma C-peptide levels and insulin metabolic clearance rate (MCR) was estimated by dividing AUC 1SR by AUC insulin. Fasting plasma insulin levels were reduced after metformin (89.3 +/- 15.9 vs 112.4 +/- 24.3 pmol l-1; p = 0.04). AUC glucose, KG and SG were similar in both tests. However, AUC insulin was reduced (39.7 +/- 6.5 vs 51.8 +/- 10.4 nmol min l-1; p = 0.02), while SI (6.98 +/- 1.14 vs 4.61 +/- 0.42 10(-5) min-1 pmol-1 l; p = 0.03) and insulin MCR (715 +/- 116 vs 617 +/- 94 ml min-1 m-2; p = 0.03) were increased after metformin. The demonstration that metformin rapidly improves insulin sensitivity should encourage further research to evaluate the long-term effects of metformin in android obese subjects with impaired oral glucose tolerance. [less ▲]

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See detailGrowth hormone response to apomorphine in panic disorder: comparison with major depression and normal controls.
Pichot, W.; Hansenne, Michel ULg; Gonzalez Moreno, A. et al

in European Archives of Psychiatry & Clinical Neuroscience (1995), 245(6), 306-8

Several lines of evidence suggest that dopamine might be involved in anxiety states. In the present study we assessed the growth hormone (GH) response to 0.5 mg apomorphine (a dopaminergic agonist) in 10 ... [more ▼]

Several lines of evidence suggest that dopamine might be involved in anxiety states. In the present study we assessed the growth hormone (GH) response to 0.5 mg apomorphine (a dopaminergic agonist) in 10 male drug-free inpatients meeting Research Diagnostic Criteria for panic disorder who were compared with 10 male major depressive inpatients and 10 male normal controls. The three groups differed significantly in the GH peak response (mean +/- SD): 27.8 +/- 12.5 ng/ml in panics, 5.4 +/- 4.0 ng/ml in major depressives, and 25.8 +/- 11.3 ng/ml in normal controls (F(2,27) = 15.3; P = 0.00003). Although there were significant differences between panics and major depressives (P = 0.00004), and between major depressives and controls (P = 0.00004), panics did not significantly differ from controls. These results do not support the hypothesis of an overlap between panic and affective disorders, and suggest that the hypothalamo-GH-somatomedin axis could be intact in panic disorder. [less ▲]

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See detailTranssexualism and connection with reality: Rorschach data
Mormont, Christian ULg; Michel, Aude; Wauthy, Jacques ULg

in Rorschachiana (1995), 20(1), 172-187

AB Presents 12 various types of responses to the Rorschach that indicate a distinctive connection with reality that seems to resemble the inability of transsexuals to resign themselves as easily to ... [more ▼]

AB Presents 12 various types of responses to the Rorschach that indicate a distinctive connection with reality that seems to resemble the inability of transsexuals to resign themselves as easily to perceived reality as to symbolic satisfactions (desired reality). The authors then compare the frequency of such responses in the Rorschach protocols of transsexuals and control subject in order to test the validity of this hypothesis. The research to be reported here involved an initial sample of 36 transsexuals, 24 men and 12 women (with the designated sex determined by the original anatomical sex). These subjects had consulted a psychologist for an evaluation that was required prior to a medical decision to perform an anatomical sex-change operation. Clinical observation indicates that transsexuals (a) correctly perceive the anatomical reality of their sex; (b) do not modify their conviction (that of belonging to the other sex) in accord with this perception; and (c) seek to resolve the resulting dissonance by changing their anatomy rather than their conviction (gender identity). On the basis of this observation, we have inferred that transsexuals should maintain a characteristic relationship with reality that we have formulated in terms of indices to be identified during Rorschach testing. [less ▲]

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See detailIncreased frequency of bronchial hyperresponsiveness in patients with inflammatory bowel disease.
Louis, Edouard ULg; Louis, Renaud ULg; Drion, V. et al

in Allergy (1995), 50(9), 729-33

Although bronchopulmonary manifestations are rare in inflammatory bowel disease (IBD), subclinical abnormalities have been described in up to 50% of cases. The pathophysiology of these abnormalities ... [more ▼]

Although bronchopulmonary manifestations are rare in inflammatory bowel disease (IBD), subclinical abnormalities have been described in up to 50% of cases. The pathophysiology of these abnormalities remains unknown. However, a latent inflammation of the bronchial mucosa secondary to the inflammation of the intestinal mucosa has been suggested. This subclinical inflammation may lead to increased bronchial responsiveness. We studied the bronchial responsiveness in 38 inflammatory bowel disease (IBD) patients, using the methacholine test. Bronchial hyperresponsiveness was defined by a PC20M < 16 mg/ml. Twenty-four healthy controls were also studied. There was no significant difference in baseline FEV1 between IBD patients and controls. However, there was a significantly greater fall in FEV1 in the IBD patients at the concentrations of methacholine tested. The frequency of bronchial hyperresponsiveness was significantly higher in the IBD population (45%) than in controls (17%; P < 0.03). Atopy, defined by skin test, was more common in IBD patients (42%) than in controls (21%). Even when only nonatopic subjects were considered, the frequency of bronchial hyperresponsiveness was significantly higher in IBD patients (41%) than in controls (5%; P < 0.02). Thus, subclinical bronchial hyperresponsiveness is common in IBD, and may be considered a further extraintestinal manifestation. [less ▲]

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See detail3-Methyl-6-(4-methylpiperazin-1-yl)-11H-pyrido[2,3-b][1,4]benzodiazepine
Dupont, l; Liégeois, Jean-François ULg; Rogister, F. et al

in Acta Crystallographica Section C-Crystal Structure Communications (1995), C51

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See detailComment j'explore ... une anemie (2eme partie).
Beguin, Yves ULg

in Revue Médicale de Liège (1995), 50(11), 487-8

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See detailEtude du miveau de contamination par les PCBs et les pesticides organochlorés de loutres (Lutra lutra) et l'anguilles (Anguilla anguilla) issues de zones humides de l'oeust de la France
Tans, Michael; Hugla, Jean Louis; Libois, Roland ULg et al

in Cahiers d'Ethologie (1995), 15(2-3-4), 321-324

Organochlorinated pesticides and PCBs were identified in 32 otter carcasses (road casualties) found in the wetlands of western France. The contamination levels are relatively low compared to those found ... [more ▼]

Organochlorinated pesticides and PCBs were identified in 32 otter carcasses (road casualties) found in the wetlands of western France. The contamination levels are relatively low compared to those found in other otter European populations. As eel is the main prey of otters in that area, samples of that fish from the Marais poitevin were analysed too. They also show a low level of contamination by these compounds, their PCB congener pattern being different. [less ▲]

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See detailFra Stein til Waldrop: sprogdigtningen og de nye prosadigtere
Delville, Michel ULg; Schatz-Jakobsen, Claus

in Den Blå Port: Tidsskrift for Litteratur (1995)

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See detailTransient respiration locomotion decoupling in galloping thoroughbreds
Jolly, Sandra ULg; Art, Tatiana ULg; Lekeux, Pierre ULg

in Equine Veterinary Journal. Supplement (1995), 18(suppl), 13-17

The compulsory respiration locomotion coupling may sometimes be broken in healthy galloping horses, leading to a `big respiratory cycle' (BRC). This work is aimed at describing the ventilatory pattern of ... [more ▼]

The compulsory respiration locomotion coupling may sometimes be broken in healthy galloping horses, leading to a `big respiratory cycle' (BRC). This work is aimed at describing the ventilatory pattern of the BRC and at studying the influence of the individual horse, gallop speed and training. Eleven healthy Thoroughbred horses were studied during a 9 week period of incremental training intensity. Instantaneous respiratory airflow, tidal volume, respiratory rate and the 02 and C02 fraction in inspired and expired gases were continuously obtained on a breath-by-breath basis during 4 standardised treadmill exercise tests (SET) performed at 3 week intervals. The inspiratory airflow of the BRC had a bi- or triphasic shape and ils inspiratory time was 1.5-fold longer than that of a normal breath. The expiratory flow was monophasic and lasted 2.5-fold longer than the normal breath. The inspiratory, but not the expiratory peak flows, remained unchanged during the BRC. The inspiratory volume was 2.0-to 1.5-fold higher than normal, according to the gallop speed. Each BRC was followed by a`readjustment cycle' (RC), which allowed the recovery of normal respiration locomotion coupling. The sum of BRC + RC times always equalled the time for 3 normal respiratory cycles. The sum of the inspiratory volumes of BRC and RC was significantly higher than the sum of their expiratory volumes. There was a highly significant effect of horse and of training on the frequency of BRC. Lastly, during the BRC and at least the 4 following respiratory cycles, the end-tidal 02 and CO, fractions were significantly lower and higher respectively. It was hypothesised that this respiratory manoeuvre could result from a negative feedback mechanism providing, at least, transiently either a readjustment of the end expiratory lung volume or an improvement of the pulmonary gas exchange [less ▲]

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See detailVaux-et-Borset : site néolithique, campagne de fouilles 1994
Caspar, Jean-Paul; Delye, Emmanuel ULg; Rochus, Noémie et al

in Chronique de l'Archéologie Wallonne (1995), 3

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See detailL'histoire de l'histoire de la médecine et ses significations. Perspectives pour une discipline en transformation
Havelange, Carl ULg

in Bulletin de l'Académie Royale de Médecine de Belgique (1995), 148 (1993)(n°10), 362-369

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See detailVentilatory and arterial blood gas tension adjustments to strenuous exercise in standardbreds
Art, Tatiana ULg; Lekeux, Pierre ULg

in American Journal of Veterinary Research (1995), 56(10), 1332-1337

Five healthy, fit Standardbreds (mean +/- SEM, 490.4 +/- 15.0 kg, 4.0 +/- 0.5 years) were studied during a standardized test carried out on a treadmill. The test consisted of an 8-minute warm-up and a 9 ... [more ▼]

Five healthy, fit Standardbreds (mean +/- SEM, 490.4 +/- 15.0 kg, 4.0 +/- 0.5 years) were studied during a standardized test carried out on a treadmill. The test consisted of an 8-minute warm-up and a 9-minute exercise period (1 minute at 1.7, 4, 7, 8, 9, and 10 m/s; 2 minutes at 4 m/s; and a 1-minute walk at a 6% slope). Respiratory airflow, tidal volume (V(T)), and respiratory frequency (f) were continuously recorded, using 2 ultrasonic pneumotachographs connected to a face mask and mass spectrometer. Oxygen uptake, carbon dioxide output, and expired minute volume (V(E)) were obtained on a breath by breath basis. Arterial blood was tested at the end of each step for O2 and CO2 partial pressures. Heart rate was continuously recorded, using a heart rate recording system. Stride frequency was measured at each step, and the stride frequency-to-f ratio was calculated. Venous blood was tested for plasma lactate concentration be fore and 2 minutes after completion of the test. Some horses had a locomotion-respiration coupling (LRC), but this coupling was occasional and intermittent. The f was lower and V(T) was higher than values reported for thoroughbreds working under similar experimental conditions. Nevertheless, maximal V(E) did not overshoot maximal V(E) reported in Thoroughbreds. All horses were hypoxemic and hypercapnic, but there was wide variability between subjects. The horses with the highest oxygen uptake and the lowest plasma lactate concentration were more hypoxemic and hypercapnic. The Standardbreds, studied under our laboratory conditions, did not have constant LRC and had lower f with higher V(T) than did Thoroughbreds under similar experimental conditions. Despite these differences in breathing strategy, the Standardbreds did not have higher V(E) than did Thoroughbreds, and they were hypoxemic and hypercapnic. The fact that these Standardbreds, which obviously freely selected their breathing strategy, were unable or unwilling to adopt compensatory hyperventilation reinforces the hypothesis that, in strenuous exercising horses, there could be a physiologic limit to ventilation, most probably related to mechanical factors, but independent of any LRC. [less ▲]

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See detailMémoire et imagerie mentale
Van der Linden, Martial ULg; Coyette, Françoise; Meulemans, Thierry ULg

in Questions de Logopédie (1995), 31

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See detailBiochemical analysis of cytoplasmic and mitochondrial Asn-tRNA synthetase functions in two mutant yeast strains.
Landrieu, Isabelle; Vandenbol, Micheline ULg; Portetelle, Daniel ULg et al

in Archives Internationales de Physiologie et de Biochimie (1995), 103

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See detailNimesulide
Dupont, L.; Pirotte, Bernard ULg; Masereel, B. et al

in Acta Crystallographica (1995), C51

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See detailApplication of sucrose synthase from rice grains for the synthesis of carbohydrates.
Elling, Lothar; Grothus, Marita; Zervosen, Astrid ULg et al

in Annals of the New York Academy of Sciences (1995), 750

The enzymatic synthesis of oligosaccharides offers an efficient way to obtain regiospecific and stereo-selective natural and nonnatural target molecules. However, the very expensive activated sugars are ... [more ▼]

The enzymatic synthesis of oligosaccharides offers an efficient way to obtain regiospecific and stereo-selective natural and nonnatural target molecules. However, the very expensive activated sugars are required as substrates for glycosyltransferases. Activated sugars are usually synthesized by pyrophosphorylases from nucleoside triphosphates and sugar-l-phosphates.'.* For cyclic in situ regeneration, at least three enzymes are needed, which makes the synthesis of, for example, N-acetyllactosamine very complex by established procedure. We report here on the enzymatic synthesis of saccharides and activated sugars by the plant glycosyltransferase sucrose synthase (EC 2.4.1.13)! The glycosyltransferase has the unique feature of catalyzing in vitro the synthesis and cleavage of sucrose (SCHEME1 ). The main advantage of sucrose synthase over pyrophosphorylases is the utilization of nucleoside diphosphates (NDP) instead of nucleoside triphosphates to generate activated sugars. [less ▲]

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See detailA general functional characterization of the microlocal singularities
Bastin, Françoise ULg; Laubin, Pascal

in Journal of Mathematical Sciences, The University of Tokyo (1995), 2(1), 155-164

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See detailMediators in critical illness
Deby, Ginette ULg; Lamy, Maurice ULg

in Current Anaesthesia and Critical Care (1995), 6(1), 3-9

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See detailVariations temporelles de la phénologie et de la composition biochimique de la phanérogame marine Posidonia oceanica en baie de Calvi
Gobert, Sylvie ULg; Belkhiria, Samy; Dauby, Patrick ULg et al

in Bulletin de la Société Royale des Sciences de Liège (1995), 64

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See detailAnomalous pion decay in effective QCD at finite temperature
Blaschke, David; Jaminon, Martine ULg; Kalinovsky, Yu. L. et al

in Nuclear Physics A (1995), 592

The width of the process π0 → γγ is calculated within effective QCD at finite temperature. We use two different effective models which describe chiral symmetry breaking and its restoration at finite ... [more ▼]

The width of the process π0 → γγ is calculated within effective QCD at finite temperature. We use two different effective models which describe chiral symmetry breaking and its restoration at finite temperature in SU(2)ƒ: (i) an effective lagrangian with a nonlocal separable interaction kernel, (ii) A- and B-scaledNJL lagrangians which implement the scale anomaly of QCD. We calculate the temperature dependences of the quark and pion masses as well as of the pion-park-antiquark coupling strength below and above the double quark mass threshold. At zero temperature we obtain a fairly good agreement with the experimental value for the decay width. The temperature dependence of the decay width is related to that of the pion mass. Γπ0 → γγ is enhanced in the vicinity of the Mott temperature (Mπ = 2mq) for the nonlocal as well as for the A-scaled model and suppressed for the B-scaled model. We compare our results with the SU(2) Nambu-Jona-Lasinio model which is contained as a limiting case in our approach. [less ▲]

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See detailRectovaginal septum, endometriosis or adenomyosis: laparoscopic management in a series of 231 patients.
Donnez, Jacques; NISOLLE, Michelle ULg; Casanas-Roux, Françoise et al

in Human Reproduction (1995), 10(3), 630-5

A series of 231 cases of deep-infiltrating endometriosis of the rectovaginal septum is presented. Laparoscopic procedures with excision of deep fibrotic endometriotic nodules were performed in all cases ... [more ▼]

A series of 231 cases of deep-infiltrating endometriosis of the rectovaginal septum is presented. Laparoscopic procedures with excision of deep fibrotic endometriotic nodules were performed in all cases. In three cases, the bowel lumen was entered. No other peri-operative complications were observed. Three cases of urinary retention were reported. The nodule resection resulted in considerable pain relief. Histologically, the rectovaginal nodule was similar to an adenomyoma. Indeed it was a circumscribed nodular aggregate of smooth muscle and endometrial glands. This form of disease must be considered as a specific disease which originates from the Mullerian rests present in the rectovaginal septum and we suggest that it be called 'rectovaginal adenomyosis'. [less ▲]

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See detailAging and text-specific implicit memory
Meulemans, Thierry ULg; Van der Linden, Martial ULg

in Psychologica Belgica (1995), 35(4), 227-239

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See detailBlues & African-American Literature. The Devil's Music in Novels of Nella Larsen,Gayl Jones and Toni Morrison. An Approach
Sacré, Robert ULg

in International Jazz Archives Journal (1995), vol.1(no.3), 93-106

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See detailPET radiopharmaceuticals in Europe : Current use and data relevant for the formulation of summaries of product characteristics (SPCs)
Meyer, G. J.; Waters, S. L.; Coenen, H. H. et al

in European Journal of Nuclear Medicine (1995), 22(12), 1420-1432

The increasing use of radiopharmaceuticals for positron emission tomography (PET) has come to the attention of regulatory bodies. In order to help authorities in all aspects, the EANM has formed a task ... [more ▼]

The increasing use of radiopharmaceuticals for positron emission tomography (PET) has come to the attention of regulatory bodies. In order to help authorities in all aspects, the EANM has formed a task group for licensing PET radiopharmaceuticals; this group has surveyed the use of these compounds in Europe by a questionnaire. The number of PET centres that responded to the questionnaire was 26, which included more than 90% of the larger European PET centres. The survey showed that 2-[18F]fluoro-2-deoxyglucose is by far the most important PET radiopharmaceutical with more than 200 applications per week, followed by [15O]water, [15O]carbonmonoxide, [13N]ammonia, [11C]-l-methionine, andl-6-[18F]fluoro-DOPA. More than 25 other PET radiopharmaceuticals are in regular use, however, at rather low application frequencies. The data were used by the European Pharmacopoeia Commission for its priority rating for requesting the formulation of monographs. Since it is likely that group registrations will be issued by authorities for the PET radiopharmaceuticals, relevant data on toxicity and dosimetry for the formulation of summaries of product characteristics have been collected by the task group as well. [less ▲]

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See detailModified glucagon test allowing simultaneous estimation of insulin secretion and insulin sensitivity: application to obesity, insulin-dependent diabetes mellitus, and noninsulin-dependent diabetes mellitus.
Castillo, M. J.; Scheen, André ULg; Lefebvre, Pierre ULg

in Journal of Clinical Endocrinology and Metabolism (1995), 80(2), 393-9

The aim of this study was to describe an adaptation of the glucagon test allowing the simultaneous characterization of insulin secretion and sensitivity. A glucagon test (1 mg/m2) was performed in healthy ... [more ▼]

The aim of this study was to describe an adaptation of the glucagon test allowing the simultaneous characterization of insulin secretion and sensitivity. A glucagon test (1 mg/m2) was performed in healthy subjects (n = 11), obese patients (n = 5), insulin-dependent diabetics (n = 9), nonobese noninsulin-dependent diabetics (n = 7), and overweight noninsulin-dependent diabetics (n = 8). Previously, they had been connected to the Biostator, modified for continuous blood collection. Endogenous insulin secretion induced by glucagon was derived from integrated C-peptide concentrations. An index of insulin sensitivity was obtained by dividing the rate of decrease in blood glucose by the total amount of insulin entering the circulation (secreted+infused by the Biostator). The indices of insulin sensitivity obtained in the above groups of subjects were, respectively, 0.064 +/- 0.006, 0.030 +/- 0.006, 0.037 +/- 0.007, 0.021 +/- 0.006, and 0.016 +/- 0.002 mmol/L.U.min (P < 0.001). The estimated insulin secretion values in the 20 min following glucagon injection were, respectively, 0.38 +/- 0.05, 0.65 +/- 0.08, 0.05 +/- 0.01, 0.26 +/- 0.15, and 0.30 +/- 0.07 U (P < 0.001). The insulin sensitivity index obtained from this test correlated with the glucose MCR obtained from a euglycemic glucose clamp (r = 0.816; P < 0.001; n = 12). C-Peptide levels after glucagon administration were also significantly correlated with the estimated endogenous insulin secretion (r = 0.808; P < 0.001; n = 30). This adaptation of the classical glucagon test is an efficient and simple method to simultaneously evaluate insulin secretion and insulin sensitivity. [less ▲]

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See detailProfondeville/Rivière: Grotte du "Bois Laiterie"
Noiret, Pierre ULg

in Chronique de l'Archéologie Wallonne (1995), 3

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See detailPiracetam-Induced Changes To Membrane Physical-Properties - A Combined Approach By P-31 Nuclear-Magnetic-Resonance And Conformational-Analysis
Peuvot, J.; Schanck, A.; Deleers, M. et al

in Biochemical Pharmacology (1995), 50(8), 1129-34

Piracetam, Nootropil (2-oxo-1-pyrrolidine acetamide), is a drug promoting erythrocyte deformability. To establish the mode of action of this compound, we have investigated its influence on the ... [more ▼]

Piracetam, Nootropil (2-oxo-1-pyrrolidine acetamide), is a drug promoting erythrocyte deformability. To establish the mode of action of this compound, we have investigated its influence on the organization of model phospholipid membranes. 31P NMR data show that the drug induces a structural modification in liposomes made of phosphatidylcholine and phosphatidylethanolamine. Our conformational analysis results have allowed the interpretation of the effect of piracetam on these model membranes: the specific interaction between the drug molecules and the phosphate headgroups induces a new organization of the lipids favouring formation of mobile drug-phospholipid complexes that exhibit an isotropic-type signal in the 31P NMR spectra. [less ▲]

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See detailImportance of Cell Kinetics Rhythmicity for the Control of Cell Proliferation and Carcinogenesis in Rat Liver (Review)
Barbason, Hervé ULg; Herens, Christian ULg; Robaye, B. et al

in In Vivo (Athens, Greece) (1995), 9(6, Nov-Dec), 539-48

The circadian control of cell Proliferation and Differentiation has been studied principally in rat liver. The comparison between the differentiation by hepatic enzymes and the division by the cell cycle ... [more ▼]

The circadian control of cell Proliferation and Differentiation has been studied principally in rat liver. The comparison between the differentiation by hepatic enzymes and the division by the cell cycle under various experimental conditions (postnatal maturation, regeneration after partial hepatectomy, adrenalectomy, corticosterone treatments etc.) leads to the following conclusions: Under physiological conditions, proliferation and differentiation activities present a mutually exclusive relationship with a specific circadian rhythm. For both functions, the circadian variation of corticosterone plays the role of synchronizer, each evening (peak) it induces the synthesis of tissue specific enzymes in G0 cells and simultaneously inhibits the DNA synthesis in cycling cells. The same parameters have been studied during the different stages of hepatocarcinogenesis induced by Diethylnitrosamine (DEN). After initiation alone, (DEN for 2 weeks) circadian control is unchanged and precancerous cells are not able to reach malignancy. Promotion (DEN for 6 weeks) consists of disturbing the circadian synchronization to liberate the selective growth of initiated precancerous cells. This proliferation advantage favours the accumulation of chromosomal aberrations including those implicated in malignant transformation: i.e. activation of oncogenes or inhibition of antioncogenes. [less ▲]

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See detailNuclear transplantation using bovine primordial germ cells from male fetuses.
Delhaise, F.; Ectors, Fabien ULg; de Roover, R. et al

in Reproduction, Fertility and Development (1995), 7(5), 1217-9

The developmental potential of nuclei of bovine gonial cells was investigated by nuclear transfer. Gonial cells were collected from male fetuses at about 175 days post coitum (p.c.). They were fused with ... [more ▼]

The developmental potential of nuclei of bovine gonial cells was investigated by nuclear transfer. Gonial cells were collected from male fetuses at about 175 days post coitum (p.c.). They were fused with enucleated oocytes; reconstituted embryos were cultured in vitro for 7 days. Embryos reaching the compacted morula or blastocyst stage were either fixed for cell counting or transferred into recipients. Out of 115 oocyte-gonia fusions, 101 (87.8%) gave rise to cleaved embryos at Day 3 and 26 (22.6%) had reached the 8-cell stage. At Day 7, 1 (1%) developed to the morula stage and 5 (4%) reached the blastocyst stage. Three blastocysts were fixed and showed normal cell numbers (135; 90; 76 cells). Three blastocysts and one morula were transferred in four recipients; two recipients were pregnant at Day 21 but only one was positive at Day 35 p.c.; this last one aborted around Day 40 p.c. No conceptus was collected. These results indicate that gonial cell nuclei can be partially reprogrammed; they are able to develop into blastocysts and to initiate gestation. However, more experiments will be necessary to prove the nuclear totipotency of bovine gonial cells. [less ▲]

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See detailMigraine and cluster headache--their management with sumatriptan: a critical review of the current clinical experience.
Wilkinson, M.; Pfaffenrath, V.; Schoenen, Jean ULg et al

in Cephalalgia : An International Journal of Headache (1995), 15(5), 337-57

Sumatriptan is a potent and selective agonist at the vascular 5HT1 receptor which mediates constriction of certain large cranial blood vessels and/or inhibits the release of vasoactive neuropeptides from ... [more ▼]

Sumatriptan is a potent and selective agonist at the vascular 5HT1 receptor which mediates constriction of certain large cranial blood vessels and/or inhibits the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater following activation of the trigeminovascular system. The mode of action of this drug in migraine and cluster headache is discussed. On the basis of a detailed review of all published trials and available data from post-marketing studies, the efficacy, safety, tolerability and the place of oral and subcutaneous sumatriptan in the treatment of both conditions are assessed. A number of double-blind clinical trials have demonstrated that sumatriptan 100 mg administered orally is clearly superior to placebo in the acute treatment of migraine headache and achieves significantly greater response rates than ergotamine or aspirin. In other studies, 70 to 80% of patients receiving sumatriptan 6 mg sc experienced relief of migraine headaches by 1 or 2 h after administration, and patients consistently required less rescue medication for unresolved symptoms. Sumatriptan was also effective in relieving associated migraine symptoms like nausea and vomiting. Sumatriptan was equally effective regardless of migraine type or duration of migraine symptoms. Overall, approximately 40% of patients who initially responded to oral or subcutaneous sumatriptan experienced recurrence of their headache usually within 24 h, effectively treated by a further dose of this drug. In 75% of patients with cluster headache treated with sumatriptan 6 mg sc, relief was achieved within 15 min. Based on pooled study data, sumatriptan is generally well tolerated and most adverse events are transient. Adverse events following oral administration include nausea, vomiting, malaise, fatigue and dizziness. With the subcutaneous injection, injection site reactions occur in approximately 30%. Chest syumptoms are reported in 3 to 5% but have been associated with myocardial ischaemia only in rare isolated cases. The recommended dosage of sumatriptan at the onset of migraine symptoms is 100 mg orally or 6 mg subcutaneously. The recommended dosage for cluster headache is 6 mg sumatriptan sc. Sumatriptan must not be given together with vasoconstrictive substances, e.g., ergotamines, or with migraine prophylactics with similar properties, e.g., methysergide. Sumatriptan should not be given during the migraine aura. It is contraindicated in patients with ischaemic heart disease, previous myocardial infarction, Prinzmetal (variant) angina and uncontrolled hypertension. [less ▲]

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See detailLa disparition de l'absorption
Kefer, Fabienne ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1995)

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See detailComment j'explore ... Une anorexie mentale.
Scheen, André ULg

in Revue Médicale de Liège (1995), 50(12), 538-9

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See detailCharacterization of monoclonal antibodies against stromelysin-3 and their use to evaluate stromelysin-3 levels in breast carcinoma by semi-quantitative immunohistochemistry
Santavicca, M.; Noël, Agnès ULg; Chenard, M. P. et al

in International Journal of Cancer = Journal International du Cancer (1995), 64(5), 336-341

Stromelysin-3 (ST3) is a matrix metalloproteinase which is expressed in fibroblastic cells of most human invasive carcinomas and represents a potential new prognostic indicator. Expression of recombinant ... [more ▼]

Stromelysin-3 (ST3) is a matrix metalloproteinase which is expressed in fibroblastic cells of most human invasive carcinomas and represents a potential new prognostic indicator. Expression of recombinant ST3 forms in Escherichia coli from cDNA constructs indicated that high levels of expression were achieved when the ST3 pro-domain was deleted. The putative mature form of ST3 thus produced and recovered from bacterial inclusion bodies was used to prepare monoclonal antibodies (MAbs) against ST3 by immunization of BALB/C mice. Ten hybridomas producing MAbs against ST3 were obtained and analyzed for their ability to detect endogenous ST3 in breast cancer and in conditioned media from human fibroblasts. One of these MAbs (5ST-4A9) was found to be suitable for the routine detection of ST3 on breast cancer tissue sections, thus opening the possibility to evaluate ST3 prognostic value in breast cancer using semi-quantitative immunohistochemistry [less ▲]

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See detailEnergy levels of High l - States in Neutral and Singly Ionized Argon
Palmeri, P.; Biémont, Emile ULg

in Physica Scripta (1995), 51

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See detailRecherche expérimentale sur le comportement au feu des colonnes en béton armé
Dotreppe, Jean-Claude ULg; Franssen, Jean-Marc ULg; Baus, Raymond et al

in Annales de l'Institut Technique du Bâtiment et des Travaux Publics (1995), 539(254), 25-41

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See detailBases biologiques du comportement suicidaire: approche neuroendocrinienne et psychophysiologique du role des catecholamines.
Pitchot, William ULg; Hansenne, Michel ULg; Gonzalez Moreno, Antonio et al

in Acta Psychiatrica Belgica (1995), 95(4-5), 210-33

The current main neurochemical theories of the biological correlates of suicidal behavior principally involve the serotonergic system. Few data are available about the possible role of the ... [more ▼]

The current main neurochemical theories of the biological correlates of suicidal behavior principally involve the serotonergic system. Few data are available about the possible role of the catecholaminergic (noradrenergic and dopaminergic) function. In the present study, in a first part, we assessed the growth hormone (GH) response to clonidine, a selective alpha 2-adrenergic agonist, and to apomorphine, a dopaminergic agonist, in 22 DSM-III-R major depressive male inpatients with a history of suicide attempts compared to 22 age-matched major depressive inpatients without history of suicidal behavior. Hormonal responses to clonidine and apomorphine were also compared with 4.00 PM postdexamethasone cortisol levels. The two groups differed significantly in the GH peak response after apomorphine: 6.27 +/- 3.18 ng/ml in suicide attempters vs 17.40 +/- 14.87 ng/ml in nonattempters (F = 11.78, p = 0.001). There was no statistically significant difference between the two groups for GH peak responses after clonidine. Moreover, mean postdexamethasone cortisol levels did not exhibit any significant difference between suicide attempters and nonattempters. Violent and nonviolent attempters did not differ on any of the biological measures. In a second part, P300 and contingent negative variation (CNV) were recorded in 20 depressive inpatients subgrouped into suicide attempters (n = 10) and nonattempters (n = 10). The results showed a significant reduction of both P300 and CNV amplitudes in patients who attempted suicide compared to patients without history of suicide attempts. Moreover, a significant correlation was found between the Suicidal Risk scale and CNV amplitude. In conclusion, these results suggest that a dopaminergic hypoactivity as assessed by a blunted GH response to apomorphine and by a reduction of both P300 and CNV amplitudes, could be considered as a biological correlate of suicidal behavior. In contrast, noradrenergic disturbances, particularly at the level of alpha 2-adrenergic receptors, seem to play a more minor role. Moreover, DST nonsuppression cannot be considered as a biological marker of suicidal behavior. [less ▲]

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See detailRegime et tactique alimentaires de la loutre (Lutra lutra) en France: synthèse.
Libois, Roland ULg

in Cahiers d'Ethologie (1995), 15(2-3-4), 251-274

More than 1500 otter spraint samples have been collected in different aquatic habitats throughout the present geographic range of the otter in France. Prey remains were identified, the relative occurrence ... [more ▼]

More than 1500 otter spraint samples have been collected in different aquatic habitats throughout the present geographic range of the otter in France. Prey remains were identified, the relative occurrence and abundance of each species was assessed and the biomass of each individual prey estimated. When available, data about the fish communities (size frequency- distributions, relative abundance) were compared with the diet of the mustelid. The main conclusions of the study are as follows: 1. The otter is mainly piscivorous but some other aquatic (crayfish) or semiaquatic preys (frogs, Natrix-snakes, some birds and mammals) are of major dietary importance in oligotrophic habitats. 2. The composition of the diet is determined by the local fish resources. The otter is an opportunistic predator, its diet varying greatly from one place to another. The diet can also change depending upon the season or upon some special circumstances such as frog or fish reproduction or strong prey-community changes. 3. Small fish are dominant in the diet. No size selection has been evidenced at least in the eel and in the cyprinid fishes. As far as the trout is concerned, it seems that the otter consumes preferably medium sized individuals. 4. The proportion of some prey species is lower in the diet than in the habitat. These are the more pelagic (bleak, sander, breams), rheophilic (dace, chub) or group-living species (minnow, roach). Bottom- (bullhead, eel, tench, gudgeon, barbel) or plant-living (rudd, pike) species are more frequent. [less ▲]

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See detailAn Atypical Anion Transporter Functioning at Acid pH in Neuroblastoma Cells
Bettendorff, Lucien ULg; Margineanu, Ilca; Wins, Pierre et al

in Biochemical and Biophysical Research Communications (1995), 207(1), 375-381

At pH 7.4, 36Cl- uptake by neuroblastoma cells was Na(+)-independent, saturable and blocked by submicromolar concentrations of DIDS. This suggests that at this pH, Cl- transport is mediated by an ... [more ▼]

At pH 7.4, 36Cl- uptake by neuroblastoma cells was Na(+)-independent, saturable and blocked by submicromolar concentrations of DIDS. This suggests that at this pH, Cl- transport is mediated by an exchanger analogous to erythroid band 3. At pH 6. [less ▲]

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See detailStatistical and Non-statistical Reactions in Energy Selected Fluoromethane Ions.
Weitzel, K.-M.; Güthe, F.; Mähnert, J. et al

in Chemical Physics (1995), 201

The unimolécular reactions of the fluoromethane ion have been investigated by the threshold photoelectron photoion coincidence technique (TPIPECO). The breakdown curves have been measured in the energy ... [more ▼]

The unimolécular reactions of the fluoromethane ion have been investigated by the threshold photoelectron photoion coincidence technique (TPIPECO). The breakdown curves have been measured in the energy range between the adiabatic ionization potential of 12.53 eV and 21 eV. In this enery range the formation of the CH2F+, CHF+, CH2+, CH3+, and CF+ fragment ions is observed. The appearance energies (AE) for these ions at 300K are 13.2, 13.91, 13.93, 14.51 and <17.7 eV respectively. The 0K threshold energy for the formation of CH2F+ ions is 13.37 eV. Two different pathways for the unimolecular reaction of the fluoromethane ion can be distinguished.The reaction proceeding through the electronic ground state of the ion is entirely statistical. In contrast to this the reaction occurring through the first electronic excited state shows non-statistical behaviour. The two pathways are distinguished via the kinetic energy released in the respective dissociation channels. While all thermodynamically allowed reaction channels are observed on the ion ground state potential, the first excited state seems to decay predominantly by F loss reaction. [less ▲]

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See detailTreatment of Clostridium difficile colitis. Summary of a round table held in Brussels on March, 3rd, 1994.
Delmée, Michel; Melin, Pierrette ULg; Peetermans, Willy et al

in Acta Clinica Belgica (1995), 50(2), 114-6

Due to the growing incidence and the severity of infections due to vancomycin resistant enterococci, it is now recommended to treat mild to moderate cases of Clostridium difficile-associated diarrhoea ... [more ▼]

Due to the growing incidence and the severity of infections due to vancomycin resistant enterococci, it is now recommended to treat mild to moderate cases of Clostridium difficile-associated diarrhoea with metronidazole while maintaining the use of oral vancomycin in serious or life-threatening colitis. Clostridium difficile is a common cause of diarrhoea after antibiotic therapy and induces a spectrum of diseases ranging from mild diarrhoea to pseudomembranous colitis (PMC). It is considered to be the first cause of diarrhoea occurring among hospitalized patients (1). [less ▲]

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See detailVaricella-zoster virus : Introduction
Rentier, Bernard ULg

in Neurology (1995), 45(12, suppl. 8), 8

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See detailEmergence of the ZNF91 Kruppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea
Bellefroid, Eric J.; Marine, Jean-Christophe; Matera, A Gregory et al

in Proceedings of the National Academy of Sciences of the United States of America (1995), 92(23), 10757-61

The ZNF91 gene family, a subset of the Kruppel-associated box (KRAB)-containing group of zinc finger genes, comprises more than 40 loci; most reside on human chromosome 19p12-p13.1. We have examined the ... [more ▼]

The ZNF91 gene family, a subset of the Kruppel-associated box (KRAB)-containing group of zinc finger genes, comprises more than 40 loci; most reside on human chromosome 19p12-p13.1. We have examined the emergence and evolutionary conservation of the ZNF91 family. ZNF91 family members were detected in all species of great apes, gibbons, Old World monkeys, and New World monkeys examined but were not found in prosimians or rodents. In each species containing the ZNF91 family, the genes were clustered at one major site, on the chromosome(s) syntenic to human chromosome 19. To identify a putative "founder" gene, > 20 murine KRAB-containing zinc finger protein (ZFP) cDNAs were randomly cloned, but none showed sequence similarity to the ZNF91 genes. These observations suggest that the ZNF91 gene cluster is a derived character specific to Anthropoidea, resulting from a duplication and amplification event some 55 million years ago in the common ancestor of simians. Although the ZNF91 gene cluster is present in all simian species, the sequences of the human ZNF91 gene that confer DNA-binding specificity were conserved only in great apes, suggesting that there is not a high selective pressure to maintain the DNA targets of these proteins during evolution. [less ▲]

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See detailRecent advances in ring-opening polymerization of lactones and related compounds
Lögfren, Anders; Albertsson, Ann-Christine; Dubois, Philippe ULg et al

in Journal of Macromolecular Science - Reviews in Macromolecular Chemistry and Physics (1995), C35(3), 379-418

Polyesters are currently synthesized by a step-growth mechanism from a mixture of a diol and a diacid (or a diacid derivative), or from a hydroxy-acid when available. Ring-opening polymerization (ROP) of ... [more ▼]

Polyesters are currently synthesized by a step-growth mechanism from a mixture of a diol and a diacid (or a diacid derivative), or from a hydroxy-acid when available. Ring-opening polymerization (ROP) of lactones and related compounds is an alternative method for the synthesis of aliphatic polyesters. Comparison of these two mechanisms is clearly in favor of the polyaddition process. The drawbacks of polycondensation are well known:high temperatures and long reaction times are required to produce high-molecular-weight chains. Even though conversion of the hydroxyl and acid group is close to completion, any departure from the reaction stoichiometry has a very detrimental effect on the chain length. [less ▲]

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See detailLa thermographie infrarouge dans l'étude de la thermorégulation : revue de la littérature
Spruyt, P.; Ghafir, Y.; Art, Tatiana ULg et al

in Annales de Médecine Vétérinaire (1995), 139

Infrared thermography is a method to assess the skin temperature by means of a camera equipped with an infrared detector. It makes thermograms that represents the surface temperature of skin patterns ... [more ▼]

Infrared thermography is a method to assess the skin temperature by means of a camera equipped with an infrared detector. It makes thermograms that represents the surface temperature of skin patterns. This article summerizes the different information about thermography and thermoregulation of horses. In fact, lots of information exist about thermoregulation of most of the domestic animais but very little exists as far as horses are concerned. Two different types of devices are used for thermography : contacting and noncontacting which measure the infrared radiation either with a thermometer or with a themographic camera. The blood circulation dictates the thermic model which is at the origin of thermographic interpretation. This latter is a good method helping to study thermoregulation. [less ▲]

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See detailP300 in posttraumatic stress disorder.
Charles, G.; Hansenne, Michel ULg; Ansseau, Marc ULg et al

in Neuropsychobiology (1995), 32(2), 72-4

In the present study, P300 has been recorded in 26 subjects (15 women) 1 month after an aggression without organic complications. Among our sample, 16 subjects fulfilled DSM-III-R criteria for ... [more ▼]

In the present study, P300 has been recorded in 26 subjects (15 women) 1 month after an aggression without organic complications. Among our sample, 16 subjects fulfilled DSM-III-R criteria for posttraumatic stress disorder (PTSD) and 10 did not. P300 amplitude was significantly lower in the 16 PTSD subjects as compared to the 10 subjects without PTSD. This study supports information processing disturbances in PTSD. [less ▲]

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See detailProgress from 1989 to 1992 in understanding the circulation of the Western Mediterranean Sea
Lehucher, P. M.; Beautier, L.; Chartier, M. et al

in Oceanologica Acta (1995), 18(2), 255-271

The present paper describes the major results obtained from 1989 to 1992 by the EUROMODEL group in studying the circulation in the Western Mediterranean Sea. Particular emphasis has been given to the ... [more ▼]

The present paper describes the major results obtained from 1989 to 1992 by the EUROMODEL group in studying the circulation in the Western Mediterranean Sea. Particular emphasis has been given to the physical processes responsible for seasonal and mesoscale variabilities. Observations (in situ and satellite), together with theoretical, physical and numerical models, have been widely used in the course of these studies. Attention has been focused on the dynamics of the northern basin (deep water formation, dynamics of the Northern Mediterranean Current, circulation and shelf/slope interaction in the Balearic Sea) and of the southern basin (Alboran Sea circulation, instabilities of the Algerian Current). The straits dynamics have been studied with particular reference to the Corsica channel. Preliminary runs of a basin-scale circulation model of the Western Mediterranean Sea forced by the straits are also presented. They are shown to be capable of generating a cyclonic circulation in the western basin. [less ▲]

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See detailHypnosis as adjunct therapy in conscious sedation for plastic surgery
Faymonville, Marie ULg; Fissette, Jean ULg; Mambourg, P.-H. et al

in Regional Anesthesia (1995), 20(2), 145-151

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See detailFurther new lichen species producing campylidia or complex conidiomata
Sérusiaux, Emmanuël ULg

in Bibliotheca Lichenologica (1995), 58

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See detailLack of LTR and ENV genetic variation during bovine leukemia virus-induced leukemogenesis.
Willems, Luc ULg; Kerkhofs, P.; Burny, A. et al

in Virology (1995), 206(1),

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See detailParticle fluxes over a Mediterranean seagrass bed: a one-year sediment trap experiment
Dauby, Patrick ULg; Bale, A. J.; Bloomer, N. et al

in Marine Ecology. Progress Series (1995), 126

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