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See detailContribution of the quantitative interpretation of gamma-ray logs to the study of limestone exploitation, a case-study at Maizeret, Belgium
Halleux, Isabelle ULg

in Geoexploration (1999), 24(6), 461-470

Economic considerations constrain quarrymen in Wallonia to consider more profit-earning exploitation of limestone deposits and (or) to diversify their products. Gamma-ray logs contain information about ... [more ▼]

Economic considerations constrain quarrymen in Wallonia to consider more profit-earning exploitation of limestone deposits and (or) to diversify their products. Gamma-ray logs contain information about the geology, structure and quality of deposits. Quantitative interpretation of the logs is necessary in order to provide a reasonably good image of reality. The method proposed here consists in removing the effects of different parameters influencing the measurements (analog ratemeter, statistical noise, etc.) and in deconvolving the data in the frequency domain by the analytical impulse response function of the system. An example demonstrates that mathematical processing increases the lithologic and stratigraphic definition of the logs (bed boundaries, bed thicknesses) and offers a satisfactory characterization of the rocks along boreholes. Some of the quarrymen's questions can be answered from this analysis. [less ▲]

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See detailCompte rendu de J. VERGER, La renaissance du XIIe siècle
George, Philippe ULg

in Moyen Age (Le) (1999)

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See detail7-Iodo-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide
Dupont, L.; Pirotte, Bernard ULg; De Tullio, Pascal ULg

in Acta Crystallographica (1999), C55

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See detailLa greffe de cellules souches hematopoietiques dans la drepanocytose.
Cornu, G.; Vermylen, C.; Ferster, Aline et al

in Archives de Pédiatrie (1999), 6 Suppl 2

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See detailLa césarienne dans l'espèce bovine
Hanzen, Christian ULg; Lourtie, O; Ectors, Francis

in Annales de Médecine Vétérinaire (1999), 143

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See detailAnalyse préliminaire de la situation et des perspectives de la culture du haricot de Lima (Phaseolus lunatus L.) sur la Côte péruvienne (Vallées d'Ica, Pisco et Casma).
Rouschop, P.; Baudoin, Jean-Pierre ULg; Mayta, F. C. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1999), 3(2), 115-126

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See detailPregnancy Associated Glycoproteins in Ruminants: Inactive Members of the Aspartic Proteinase Family
Beckers, Jean-François ULg; Drion, Pierre ULg; Garbayo, J. M. et al

in Acta Veterinaria Hungarica (1999), 47(4), 461-9

The Pregnancy Associated Glycoproteins (PAGs) presented in this paper are largely expressed in the ruminant placenta. These proteins are classified as probably inactive members of the aspartic proteinase ... [more ▼]

The Pregnancy Associated Glycoproteins (PAGs) presented in this paper are largely expressed in the ruminant placenta. These proteins are classified as probably inactive members of the aspartic proteinase family. Pepsinogen, renin, cathepsin E [less ▲]

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See detailCompte-rendu de Jocelyn Benoist, L'a priori conceptuel. Bolzano, Husserl, Schlick
Leclercq, Bruno ULg

in Recherches Husserliennes (1999), 12

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See detailAlcoholic's deficit in the decoding of emotional facial expression
Philippot, P; Kornreich, C; Blairy, Sylvie ULg et al

in Alcoholism, Clinical & Experimental Research (1999), 23(6), 1031-1038

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See detailThe Molecular Neuron-Glia Couple and Epileptogenesis
Grisar, Thierry ULg; Lakaye, Bernard ULg; Thomas, E. et al

in Advances in Neurology (1999), 79

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See detailThe neural correlates of updating information in verbal working memory
Van der Linden, Martial ULg; Collette, Fabienne ULg; Salmon, Eric ULg et al

in Memory (1999), 7(5-6), 549-560

The aim of the present study was to re-examine cerebral areas subserving the updating function of the central executive with a running span task requiring subjects to watch strings of consonants of ... [more ▼]

The aim of the present study was to re-examine cerebral areas subserving the updating function of the central executive with a running span task requiring subjects to watch strings of consonants of unknown length and then to recall serially a specific number of recent items. In order to dissociate more precisely the updating process from the storage function, a four-item instead of a six-item memory load was used, contrary to our previous study (Salmon et al., 1996). In addition, a serial recall procedure was preferred to a recognition procedure in order to suppress the use of visuospatial strategies. The most significant increase of rCBF occurred in the left frontopolar cortex (Brodmann's area 10), spreading to the left middle frontal (Brodmann's area 46). Results suggest that frontopolar activation underlies an updating process in working memory. [less ▲]

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See detailOncologie gastro-intestinale
Coucke, Philippe ULg; FREI; FELLEY et al

in Médecine et Hygiène (1999), 57(2240), 213-217

Même si aucune acquisition nouvelle n'est venue embaumer l'atmosphère encore trop souvent grisâtre de l'oncologie gastro-intestinale en 1998, la nécessité d'un consilium préthérapeutique associant ... [more ▼]

Même si aucune acquisition nouvelle n'est venue embaumer l'atmosphère encore trop souvent grisâtre de l'oncologie gastro-intestinale en 1998, la nécessité d'un consilium préthérapeutique associant chirurgiens, endoscopeurs, oncologues et radio-oncologues s'impose avec encore plus de fermeté, pour tous les cancers digestifs. Les patients devraient autant que possible être inclus dans des protocoles d'études bien conduits et bénéficier d'une chirurgie oncologique optimale. [less ▲]

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See detailA procedure for deriving accurate linear polarimetric measurements.
Lamy, H.; Hutsemekers, Damien ULg

in The Messenger (1999), 96

The authors present here a procedure written within the ESO MIDAS reduction package with the aim of deriving semi-automatically linear polarisation data from CCD images obtained with beam-splitters such ... [more ▼]

The authors present here a procedure written within the ESO MIDAS reduction package with the aim of deriving semi-automatically linear polarisation data from CCD images obtained with beam-splitters such as those available at the ESO 3.6-m telescope equipped with EFOSC2 or at the VLT equipped with FORS1. The method is adequate for point-like objects and was used for measuring quasar polarisation. [less ▲]

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See detailLes conditions de la rentabilité de la production d'embryons bovins par ponction folliculaire échoguidée et fécondation in vitro en Région Wallonne : première approche.
Dehareng, D.; Annet, C.; Dupont, F. et al

in Annales de Médecine Vétérinaire (1999), 143

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See detailImmunocytochemistry of lipids : chemical fixatives have dramatic effects on the preservation of tissue lipids
Maneta-Peyret, Lilly; Compère, Philippe ULg; Moreau, Patrick et al

in Histochemical Journal (The) (1999), 31

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See detailLa découverte d'or natif dans le quartzite devellien de Hourt autorise un autre regard sur le site de Rompt-le-Cou
Hanson, Alain ULg; Dehove, J.; Debbaut, Vincent ULg et al

in Glain et Salm. Haute Ardenne (1999), 51

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See detailGezelle, mens en onmens
Spinoy, Erik ULg

in Gezelliana. Kroniek van de Gezellestudie (1999)

This article reflects on how the work of the reactionary 19th-century Flemish poet Guido Gezelle can be 'saved' through innovative rereadings.

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See detailImmunohistochemical study of the proliferation index, oestrogen receptors and progesterone receptors A and B in leiomyomata and normal myometrium during the menstrual cycle and under gonadotrophin-releasing hormone agonist therapy
NISOLLE, Michelle ULg; Gillerot, Stéphane; Casanas-Roux, Françoise et al

in Human Reproduction (1999), 14(11), 2844-2850

The cell proliferation-associated antigen Ki 67 and the immunohistochemical content of oestrogen receptors (ER), progesterone receptors AB (PRAB) and progesterone receptors B (PRB) were evaluated in ... [more ▼]

The cell proliferation-associated antigen Ki 67 and the immunohistochemical content of oestrogen receptors (ER), progesterone receptors AB (PRAB) and progesterone receptors B (PRB) were evaluated in leiomyomata and adjacent myometrium during the menstrual cycle and in leiomyomata under gonadotrophin-releasing hormone agonist (GnRHa) therapy. The proliferative status of muscular cells was measured by evaluating the percentage of nuclei staining positive for Ki 67 (proliferation index). Quantitative analysis (QH-score) was carried out using advanced stereographic computer technology to investigate ER, PRAB and PRB. Leiomyoma and myometrial biopsies were taken from 30 patients undergoing hysterectomy or myomectomy because of symptomatic leiomyomata (subgroup I). Leiomyoma biopsies were taken from 10 patients suffering from symptomatic submucosal leiomyomata, after 2 month GnRH therapy (subgroup II). During the secretory phase, the proliferation index (Ki 67) was found to be higher in leiomyomata than in myometrium, but the difference was not significant. Oestrogen receptor content was significantly higher in leiomyomata than in myometrium only during the proliferative phase of the cycle. PRAB and PRB content were found to be higher in leiomyomata than in adjacent myometrium with a statistically significant dominance of PRAB over PRB. Under GnRHa therapy, a dramatic decrease was observed in PRAB and B content as well as Ki 67 but ER content remained comparable with the results obtained during the menstrual cycle. The results suggest that leiomyomata may be under the influence of progesterone which may play a major role in their growth. [less ▲]

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See detailComparing global models of terrestrial net primary productivity (NPP): analysis of the seasonal atmospheric CO2 signal
Nemry, B.; François, Louis ULg; Gérard, Jean-Claude ULg et al

in Global Change Biology (1999), 5(Suppl. 1), 65-76

Eight terrestrial biospheric models (TBMs) calculating the monthly distributions of both net primary productivity (NPP) and soil heterotrophic respiration (R-H) in the Potsdam NPP Model Intercomparison ... [more ▼]

Eight terrestrial biospheric models (TBMs) calculating the monthly distributions of both net primary productivity (NPP) and soil heterotrophic respiration (R-H) in the Potsdam NPP Model Intercomparison workshop are used to simulate seasonal patterns of atmospheric CO2 concentration. For each model, we used net ecosystem productivity (NEP=NPP-R-H) as the source function in the TM2 atmospheric transport model from the Max-Planck Institute for Meteorology. Comparing the simulated concentration fields with detrended measurements from 25 monitoring stations spread over the world, we found that the decreasing seasonal amplitude from north to south is rather well reproduced by all the models, though the amplitudes are slightly too low in the north. The agreement between the simulated and observed seasonality is good in the northern hemisphere, but poor in the southern hemisphere, even when the ocean is accounted for. Based on a Fourier analysis of the calculated zonal atmospheric signals, tropical NEP plays a key role in the seasonal cycle of the atmospheric CO2 in the whole southern hemisphere. The relatively poor match between measured and predicted atmospheric CO2 in this hemisphere suggests problems with all the models. The simulation of water relations, a dominant regulator of NEP in the tropics, is a leading candidate for the source of these problems. [less ▲]

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See detailDiagnostiquer les Troubles Spécifiques de l'Apprentissage
Garcet, Serge ULg

in Revue Scientifique de l'AIGS, (1999), 2

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See detailRadiative Properties of Neutral Germanium obtained from excited-state lifetime and branching-ratio measurements and comparison with theoretial calculations
Li, Z. S.; Norin, J.; Persson, A. et al

in Physical Review. A (1999), 60

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See detailThe Locus for Enterocyte Effacement (Lee) of Enteropathogenic Escherichia Coli (Epec) from Dogs and Cats
Goffaux, F.; China, B.; Janssen, L. et al

in Advances in Experimental Medicine and Biology (1999), 473

Enteropathogenic Escherichia coli (EPEC) produce attaching and effacing lesions. The genes responsible for this lesion are clustered on the chromosome forming a 35.5 kilobase pathogenesis island called ... [more ▼]

Enteropathogenic Escherichia coli (EPEC) produce attaching and effacing lesions. The genes responsible for this lesion are clustered on the chromosome forming a 35.5 kilobase pathogenesis island called LEE. The LEE was identified, characterized and completely sequenced from the human EPEC strain E2348/69. The LEE carries genes coding for: a type III secretion system (genes esc and sep), the translocated intimin receptor (gene tir), the outer membrane protein intimin (gene eae) and the E. coli secreted proteins EspA, EspB, and EspD (genes esp). In addition to man and farm animals, EPEC are also isolated from dogs and cats. We studied structurally and functionally the LEE of dog and cat EPEC. First, we used four probes scattered along the LEE to identify the presence of a LEE in canine and feline EPEC isolates. Second, by PCR, we checked the presence of genes homologous to eae, sep, esp, and tir genes in these strains. Third, since the four types of eae and tir genes were described, we developed a multiplex PCR in order to determine the type of eae and tir genes present in each strain. Fourth, we determined by PCR the site of the LEE insertion on the chromosome. Fifth, we tested several of the canine EPEC in their capacity to induce attaching and effacing lesions in the rabbit intestinal loop assay. We can conclude from this study: first, that the a LEE-like structure is present in all tested strains and that it contains genes homologous to esp, sep, tir, and eae genes; second, that there is some preferential associations between the type of eae gene and the type of tir gene present in a strain; third, that the majority of the tested strains contained a LEE located elsewhere on the chromosome in comparison to the human EPEC strain E2348/69; and fourth that dog EPEC were able to induce attaching and effacing lesions in rabbit ileal loop assay. [less ▲]

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See detailDissection of the GHER turbulence closure scheme
Delhez, Eric ULg; Grégoire, Marilaure ULg; Nihoul, Jacques ULg et al

in Journal of Marine Systems (1999), 21(1-4), 379-397

In this paper, the turbulence closure scheme implemented in the GHER hydrodynamic model is described in detail. Two case studies carried out in two contrasting conditions-one in the shallow, tide ... [more ▼]

In this paper, the turbulence closure scheme implemented in the GHER hydrodynamic model is described in detail. Two case studies carried out in two contrasting conditions-one in the shallow, tide dominated, north-western European continental shelf, and the other in the deep Mediterranean Sea-are used to identify the dominant terms of the equation for the turbulent kinetic energy, first theoretically, secondly from the results of the simulations. In both domains, the dominant terms are the local destruction and production terms, the vertical diffusion term and to a smaller degree, the time derivative. Advection and horizontal diffusion turn out to be negligible in most of the relevant cases for such large scale studies. This opens the way to simplifications and optimisations of the numerical models. (C) 1999 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailTreatment of Inflammatory Bowel Disease with Azathioprine: How to Use It in 1999
Louis, Edouard ULg; Belaiche, Jacques ULg

in Acta Gastro-Enterologica Belgica (1999), 62(4, Oct-Dec), 437-9

Azathioprine and 6-mercaptopurine are effective drugs in the management of steroid dependent and chronic active inflammatory bowel diseases. They are also well tolerated on the long term. However, their ... [more ▼]

Azathioprine and 6-mercaptopurine are effective drugs in the management of steroid dependent and chronic active inflammatory bowel diseases. They are also well tolerated on the long term. However, their use is still hampered by some drawbacks including delay before efficacy, 20-35% of non responders, relapse at withdrawal of the drugs, possible bone marrow toxicity and other side effects. During the last few years, these drawbacks have been challenged by important studies showing that a better knowledge of the metabolism of these drugs may help to improve their use. [less ▲]

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See detailA sharp decrease of resistivity in La0.7Ca0.3Mn0.96Cu0.04O3: Evidence for Cu-assisted coherent tunneling of spin polarons
Sergeenkov, S. A.; Bougrine, Hassan ULg; Ausloos, Marcel ULg et al

in JETP Letters (1999), 69(11), 858-862

Nearly a 50% decrease of the resistivity rho(T,x) is observed upon just 4% Cu doping at the Mn site of La2/3Ca1/3Mn1-xCuxO3. When the observed phenomenon is attributed to a decrease of the spin-polaron ... [more ▼]

Nearly a 50% decrease of the resistivity rho(T,x) is observed upon just 4% Cu doping at the Mn site of La2/3Ca1/3Mn1-xCuxO3. When the observed phenomenon is attributed to a decrease of the spin-polaron energy E-sigma(x) below T-C(x), all of the data are found to be well fitted by the nonthermal coherent tunneling expression rho(T,x)=rho(0)e(-gamma M2(T,x)), assuming that the magnetization in the ferromagnetic state is given by the expression M(T,x)=M-R(x)+M-0(x)tanh{T-[root(C)(x)/T](2)-1}. The best fits through all the data points suggest M-0(x)similar or equal to root 1-xM(0)(0), M-R(x)similar or equal to x root M-0(0), and E-sigma(x)similar or equal to E-sigma(0)(1-x)(4) for the explicit x dependence of the Cu-induced modifications of the Mn-spin-dominated zero-temperature spontaneous magnetization, residual paramagnetic contribution, and spin-polaron tunneling energy, respectively, with E-sigma(0)=0.12 eV. (C) 1999 American Institute of Physics. [S0021-3640(99)00811-7]. [less ▲]

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See detailMaladie de Crohn. Récidives post-opératoires. Conduite à tenir.
Belaiche, Jacques ULg; Louis, Edouard ULg

in Acta Endoscopica (1999), 29

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See detailNegative magnetoresistance in mixed-valence La0.6Y0.1Ca0.3MnO3: Evidence for charge localization governed by the Curie-Weiss law
Sergeenkov, S.; Bougrine, Hassan ULg; Ausloos, Marcel ULg et al

in JETP Letters (1999), 70(2), 141-146

The colossal negative magnetoresistance Delta rho observed in La0.6Y0.1Ca0.3MnO3 at B=1 T shows an unusual, nearly perfect symmetry (around the peak temperature T-0=160 K), suggestive of a Curie-Weiss ... [more ▼]

The colossal negative magnetoresistance Delta rho observed in La0.6Y0.1Ca0.3MnO3 at B=1 T shows an unusual, nearly perfect symmetry (around the peak temperature T-0=160 K), suggestive of a Curie-Weiss-dominated transport mechanism in this material both above and below the field-dependent Curie temperature T(C)equivalent to T-0. Attributing this symmetry to strong magnetic fluctuations below T-C (which are triggered by the Y substitution and cause a "bootstrap" destruction of the ferromagnetic phase), the data are interpreted in terms of the nonthermal spin hopping and magnetization-dependent charge carrier localization scenario leading to Delta rho=-rho(s)(1-e(-gamma M2)), with the magnetization M(T,B)=CB/\ T-T-C(B)\(nu). The separate fits through all the data points above and below T-C yield C(+)similar or equal to 2C(-) and nu(+)similar or equal to nu(-)similar or equal to 1, in agreement with the predictions of the Landau mean-field theory. (C) 1999 American Institute of Physics. [S0021-3640(99)01314-6]. [less ▲]

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See detailUDP-N-Acetyl-alpha-D-glucosamine as acceptor substrate of beta-1,4-galactosyltransferase. Enzymatic synthesis of UDP-N-acetyllactosamine.
Elling, Lothar; Zervosen, Astrid ULg; Gallego, Ricardo Gallego et al

in Glycoconjugate Journal (1999), 16(7), 327-36

The capacity of UDP-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) as an in vitro acceptor substrate for beta-1,4-galactosyltransferase (beta4GalT1, EC 2.4.1.38) from human and bovine milk and for recombinant ... [more ▼]

The capacity of UDP-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) as an in vitro acceptor substrate for beta-1,4-galactosyltransferase (beta4GalT1, EC 2.4.1.38) from human and bovine milk and for recombinant human beta4GalT1, expressed in Saccharomyces cerevisiae, was evaluated. It turned out that each of the enzymes is capable to transfer Gal from UDP-alpha-D-galactose (UDP-Gal) to UDP-GlcNAc, affording Gal(beta1-4)GlcNAc(alpha1-UDP (UDP-LacNAc). Using beta4GalT1 from human milk, a preparative enzymatic synthesis of UDP-LacNAc was carried out, and the product was characterized by fast-atom bombardment mass spectrometry and 1H and 13C NMR spectroscopy. Studies with all three beta4GalTs in the presence of alpha-lactalbumin showed that the UDP-LacNAc synthesis is inhibited and that UDP-alpha-D-glucose is not an acceptor substrate. This is the first reported synthesis of a nucleotide-activated disaccharide, employing a Leloir glycosyltransferase with a nucleotide-activated monosaccharide as acceptor substrate. Interestingly, in these studies beta4GalT1 accepts an alpha-glycosidated GlcNAc derivative. The results imply that beta4GalT1 may be responsible for the biosynthesis of UDP-LacNAc, previously isolated from human milk. [less ▲]

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See detailOverexpression, purification and characterization of Mycobacterium bovis BCG alcohol dehydrogenase.
Wilkin, J. M.; Soetaert, K.; Stelandre, M. et al

in European Journal of Biochemistry (1999), 262(2), 299-307

A previous study of the effect of zinc deprivation on Mycobacterium bovis BCG pointed out the potential importance of an alcohol dehydrogenase for maintaining the hydrophobic character of the cell ... [more ▼]

A previous study of the effect of zinc deprivation on Mycobacterium bovis BCG pointed out the potential importance of an alcohol dehydrogenase for maintaining the hydrophobic character of the cell envelope. In this report, the effect of the overexpression of the M. bovis BCG alcohol dehydrogenase (ADH) in Mycobacterium smegmatis and M. bovis BCG is described. The purification of the enzyme was performed to apparent homogeneity from overexpressing M. bovis BCG cells and its kinetic parameters were determined. The enzyme showed a strong preference for both aromatic and aliphatic aldehydes while the corresponding alcohols were processed 100-1000-fold less efficiently. The best kcat/Km values were found with benzaldehyde > 3-methoxybenzaldehyde > octanal > coniferaldehyde. A phylogenetic analysis clearly revealed that the M. bovis BCG ADH together with the ADHs from Bacillus subtilis and Helicobacter pylori formed a sister group of the class C medium-chain alcohol dehydrogenases, the plant cinnamyl alcohol dehydrogenases (CADs). Comparison of the kinetic properties of our ADH with some related class C enzymes indicated that the mycobacterial enzyme substrate profile resembled that of the CADs involved in plant defence rather than those implicated in lignification. A possible role for the M. bovis BCG ADH in the biosynthesis of the lipids composing the mycobacterial cell envelope is proposed. [less ▲]

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See detailFrom Neural Stem Cells to Myelinating Oligodendrocytes
Rogister, Bernard ULg; Ben Hur, Tamir; Dubois-Dalcq, Monique

in Molecular & Cellular Neuroscience [=MCN] (1999), 14

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See detailLa Société nationale de la Petite Propriété Terrienne, Une institution entre ville et campagne
Mougenot, Catherine ULg

in Cahiers de l'Urbanisme (Les) (1999), (25-26), 42-45

Les maisons « terriennes » font partie de bon nombre de villes et villages. On connait pourtant mal l’origine de ces nombreux quartiers dont l’histoire se fonde dans l’attachement au jardin et la maitrise ... [more ▼]

Les maisons « terriennes » font partie de bon nombre de villes et villages. On connait pourtant mal l’origine de ces nombreux quartiers dont l’histoire se fonde dans l’attachement au jardin et la maitrise d’un environnement proche, un attrait que l’on redécouvre largement aujourd’hui. [less ▲]

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See detailEffects Of Galanin Infusion On Gh Secretion And Ghrh-Induced Gh Release In Prepubertal Male Lambs
Saleri, R.; Baratta, M.; Renaville, Robert ULg et al

in Small Ruminant Research (1999), 33(3),

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See detailPubertal Growth as a Determinant of Adult Height in Boys with Constitutional Delay of Growth and Puberty
Rensonnet, Claudie ULg; Kanen, F.; Coremans, C. et al

in Hormone Research (1999), 51(5), 223-9

In boys with constitutional delay of growth and puberty, adult height may be inconsistent with parental (target) height. We aimed at studying which period of growth was important to account for adult ... [more ▼]

In boys with constitutional delay of growth and puberty, adult height may be inconsistent with parental (target) height. We aimed at studying which period of growth was important to account for adult height being above or below target height. In this retrospective study, adult height measured after 20 years in 39 patients was compared with target height and height data obtained at about 6 and 12 years of age and at diagnosis of delayed puberty (mean 14.6 years). Twenty-eight patients were untreated while 11 received testosterone enanthate (50 or 100 mg/month for 6 months). The growth data from both groups were pooled since they were not different. On average, the adult height standard deviation score (-0. 6 +/- 0.8, mean +/- SD) was similar to target height (-0.5 +/- 0.6). There were, however, marked individual differences since adult height varied between 1.7 SD (11 cm) below target height and 1.4 SD (9.5 cm) above target height. Multiple regression analysis showed that the most significant determinant of the difference between adult height and target height was height catch up during puberty (p < 0.002). We conclude that the magnitude of height catch up during puberty is a significant determinant of adult height in boys with constitutional delay of growth and puberty. Thus, optimizing pubertal growth may be a relevant therapeutic aim for adult height in boys with short stature and delayed puberty. Copyrightz1999S. KargerAG,Basel [less ▲]

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See detailHarm avoidance and serotonin.
Hansenne, Michel ULg; Ansseau, Marc ULg

in Biological Psychology (1999), 51(1), 77-81

The relationships between the Tridimensional Personality Questionnaire (TPQ) and serotonergic activity has been described in some studies with controversial results. These studies have focused on specific ... [more ▼]

The relationships between the Tridimensional Personality Questionnaire (TPQ) and serotonergic activity has been described in some studies with controversial results. These studies have focused on specific patient populations rather than normal controls. Therefore, the aim of the present study is to examine the relationships between the TPQ and serotonergic activity in a group of non-patient subjects. Twenty-three normal subjects answered the TPQ, and the serotonergic activity was assessed by the prolactin response to a highly potent and selective 5-HT1a agonist (flesinoxan). A positive relationship between harm avoidance and PRL response to flesinoxan was found. This study is consistent with the hypothesized link between serotonergic activity and the harm avoidance dimension of the biosocial model of Cloninger. [less ▲]

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See detailImmunohistochemical study of the rectus sheath and transversalis facia in adult groin hernias
PANS, Alain ULg; Pierard, Gérald ULg; Albert, Adelin ULg

in Hernia : the Journal of Hernias & Abdominal Wall Surgery (1999), 3

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See detailStudies of the glutathione S-transferases activities and their localisation in Adalia bipunctata L. (Coleoptera : Coccinellidae).
Francis, Frédéric ULg; Broon, D.; Haubruge, Eric ULg

in Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen (Rijksuniversiteit te Gent) (1999), 64(3a), 349-355

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See detailHigh Prevalence of Low Femoral Bone Mineral Density in Elderly Women Living in Nursing Homes or Community-Dwelling: A Plausible Role of Increased Parathyroid Hormone Secretion
Reginster, Jean-Yves ULg; Deroisy, Rita ULg; Pirenne, H. et al

in Osteoporosis International (1999), 9(2), 121-8

The present study was designed to visit elderly women living in nursing homes and to compare their femoral neck bone mineral density (BMD) and circulating levels of parathyroid hormone (PTH) and 25-OH ... [more ▼]

The present study was designed to visit elderly women living in nursing homes and to compare their femoral neck bone mineral density (BMD) and circulating levels of parathyroid hormone (PTH) and 25-OH vitamin D (25-OHD) with those of subjects living at home, in the immediate vicinity of the nursing homes. Of 1483 women, aged 70 years and older, who were selected, 993 agreed to participate in this trial. Their femoral neck BMD (n = 993) was measured by dual-energy X-ray absorptiometry, with a specific device installed in a mobile truck. The circulating levels of 25-OHD and PTH were assessed after an overnight fast (n = 748). After stratification for age, there were no significant differences in mean femoral neck BMD values, prevalence of femoral neck osteoporosis, mean serum 25-OHD and prevalence of absolute or relative 25-OHD deficiency between the two groups. Serum levels of PTH were significantly higher in women over 80 years old living in nursing homes, compared with the community-dwelling women. After adjustment for age, a significant relation was found between femoral neck BMD and PTH levels in the whole population (p = 0.004) and in community-dwelling subjects (p = 0.039). When stratifying our population by quartiles of serum PTH values, the odds ratios for femoral neck osteoporosis were significantly increased for the top two quartiles compared with the lowest one both before (p = 0.00146) and after (p = 0.0013) adjustment for age and type of housing. From this study we conclude that femoral osteoporosis is largely underestimated in European women. Living in a nursing home is not, per se, a risk factor for decreased femoral BMD, and circulating PTH levels are a key determinant of low femoral bone density and osteoporosis. [less ▲]

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See detailDevelopment of a coupled flow and transport 3D model for simulating seawater intrusions in coastal aquifers
Carabin, Guy; Dassargues, Alain ULg

in Natuurwetenschappelijk Tijdschrift (1999), 79

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See detailObservations sous Prés. Com. Bruxelles, 27 avril 1999
Boularbah, Hakim ULg

in Revue de Droit Commercial Belge [= RDC] = Tijdschrift voor Belgisch Handelsrecht [=TBH] (1999)

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See detailBovine herpesvirus 1-induced apoptotic cell death: role of glycoprotein D
Hanon, Emmanuel; Keil, Günther; Van Drunen Littel-Van Den Hurk, Sylvia et al

in Virology (1999), 257

Bovine herpesvirus 1 (BHV-1) induces apoptotic cell death in peripheral blood mononuclear cells and in bovine B lymphoma (BL-3) cells. Attachment but not penetration of BHV-1 is necessary to induce ... [more ▼]

Bovine herpesvirus 1 (BHV-1) induces apoptotic cell death in peripheral blood mononuclear cells and in bovine B lymphoma (BL-3) cells. Attachment but not penetration of BHV-1 is necessary to induce apoptosis in target cells, suggesting that one or more BHV-1 envelope glycoproteins could be involved in the activation of the apoptotic process. In the present study, we demonstrate that, although BHV-1 virions devoid of glycoprotein D (BHV-1 gD-/-) still bind to BL-3 cells, they are no longer able to induce apoptosis. In contrast, virions that contain glycoprotein D (gD) in the viral envelope but do not genetically encode gD (BHV-1 gD-/+) induce a level of apoptosis comparable to that produced by wild-type (wt) BHV-1. In addition, monoclonal antibodies directed against gD, but not against gB or gC, strongly reduced the high levels of apoptosis induced by BHV-1. These observations demonstrate that the induction of apoptosis is directly due to BHV-1 viral particles harboring gD in the viral envelope. Interestingly, binding of affinity-purified gD to BL-3 cells did not induce apoptosis but inhibited the ability of wt BHV-1 to induce apoptosis. Altogether, these results provide evidence for the direct or indirect involvement of gD in the mechanism by which BHV-1 induces apoptosis. [less ▲]

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See detailRadio-oncologie et radiothérapie. Confirmation de l'efficacité des radiations ionisantes en oncologie, et renouveau de leur intérêt dans les affections non oncologiques : Acquisitions thérapeutiques 1998
OZSAHIN; MIRIMANOFF; PICA, A et al

in Médecine et Hygiène (1999), 54(2238), 100-111

En 1998, plusieurs études ont clarifié ou confirmé l'effet positif de la radiothérapie dans le cancer du sein in situ, dans différents types de lymphomes non hodgkinien et hodgkinien, et dans le cancer ... [more ▼]

En 1998, plusieurs études ont clarifié ou confirmé l'effet positif de la radiothérapie dans le cancer du sein in situ, dans différents types de lymphomes non hodgkinien et hodgkinien, et dans le cancer bronchique à petites cellules. Deux métaanalyses par contre semblent remettre en cause la radiothérapie, dans la maladie de Hodgkin de stade avancé et dans l'approche postopératoire du cancer ronchique à non petites cellules. Ces méta-analyses comportent toutefois d'importantes faiblesses et doivent être interprétées de façon critique. Dans le domaine technique de la radio-oncologie, les progrès spectaculaires de la planification assistée par ordinateur et l'intégration de l'imagerie IRM peuvent maintenant s'appliquer aussi à la curiethérapie. Enfin, la radiothéraple dans les affections non oncologiques suscite un nouvel intérêt, comme par exemple la curiethérapie intracoronarienne, un traitement prometteur pour prévenir la resténose coronarienne. [less ▲]

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See detailSymbolic Verification of Communication Protocols with Infinite State Spaces using QDDs
Boigelot, Bernard ULg; Godefroid, Patrice

in Formal Methods in System Design (1999), 14(3), 237-255

We study the verification of properties of communication protocols modeled by a finite set of finite-state machines that communicate by exchanging messages via unbounded FIFO queues. It is well-known that ... [more ▼]

We study the verification of properties of communication protocols modeled by a finite set of finite-state machines that communicate by exchanging messages via unbounded FIFO queues. It is well-known that most interesting verification problems, such as deadlock detection, are undecidable for this class of systems. However, in practice, these verification problems may very well turn out to be decidable for a subclass containing most "real" protocols. Motivated by this optimistic (and, we claim, realistic) observation, we present an algorithm that may construct a finite and exact representation of the state space of a communication protocol, even if this state space is infinite. Our algorithm performs a loop-first search in the state space of the protocol being analyzed. A loop-first search is a search technique that attempts to explore first the results of successive executions of loops in the protocol description (code). A new data structure named Queue-content Decision Diagram (QDD) is introduced for representing (possibly infinite) sets of queue-contents. Operations for manipulating QDDs during a loop-first search are presented. A loop-first search using QDDs has been implemented, and experiments on several communication protocols with infinite state spaces have been performed. For these examples, our tool completed its search, and produced a finite symbolic representation for these infinite state spaces. [less ▲]

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See detailEffects of Nimesulide and Indometacin on Cox-1 and Cox-2: A Comparative Study
de Leval, X.; Dogné, Jean-Michel ULg; Neven, P. et al

in Journal de Pharmacie de Belgique (1999), 54(3), 89-90

Evidence of the existence of two forms of cyclooxygenases and the clinical relevance of COX-2 inhibition led to the development of COX-2 selective NSAIDs. In order to evaluate this selectivity, we have ... [more ▼]

Evidence of the existence of two forms of cyclooxygenases and the clinical relevance of COX-2 inhibition led to the development of COX-2 selective NSAIDs. In order to evaluate this selectivity, we have developed and validated an enzymatic method. The precision and reproducibility of the assay were determined and COX-2 selectivity examined using nimesulide and indometacin. [less ▲]

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See detailGerhard Herzberg (1904-1999)
Biémont, Emile ULg; Dubois, I.

in Annuaire Cl. Sc. Acad. Roy. (1999), X

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See detailGEQUAC, an excess Gibbs energy model describing associating and non-associating liquid mixtures by a new model concept for functional groups
Egner, Katja; Gaube, Johann; Pfennig, Andreas ULg

in Fluid Phase Equilibria (1999), 158(381-389),

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See detailSite index curves and autecology of ash, sycamore and cherry in Wallonia (Southern Belgium)
Claessens, Hugues ULg; Pauwels, Dominique; Thibaut, André et al

in Forestry (1999), 72(3), 171-182

The work described in this article forms part of an exploratory study whose aim was to determine the main aspects of the autecology of ash (Fraxinus excelsior L.), sycamore (Acer pseudoplatanus L.) and ... [more ▼]

The work described in this article forms part of an exploratory study whose aim was to determine the main aspects of the autecology of ash (Fraxinus excelsior L.), sycamore (Acer pseudoplatanus L.) and cherry (Prunus avium L.) in Wallonia (Southern Belgium). The potential productivity of these species was studied using the site index approach (the height a crop achieves at a given age) which is the most widely accepted means for estimating site quality. As a first step, a set of site index curves were constructed from stem analysis and semi-permanent plots data using the Johnson (1935) and Schumacher (1939) model for ash and the Duplat and Tran-Ha (1986) model II for sycamore and cherry. For ash, dominant height achieved at age 50 is related to various soil-site characters (through adequate multiple regression analysis) in order to make the predictions of site quality applicable to both forested and non-forested land. Furthermore the sites expressed through soil attributes are classified in 'a site catalogue' for each species according to their productivity level. [less ▲]

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See detailEther suicide poisoning by intravenous injection
LAMBERMONT, Bernard ULg; D'Orio, Vincenzo ULg

in Intensive Care Medicine (1999), 25(3), 338

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See detailMalathion Resistance Increases Male Reproductive Success In Tribolium Castaneum (Coleoptera : Tenebrionidae)
Arnaud, L.; Haubruge, Eric ULg; Gaspar, Charles ULg

in Annales de la Societe Entomologique de France (1999), 35

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See detailDesign of a microwave array hyperthermia applicator with a semicircular reflector
V Sabariego, Ruth ULg; Landesa, Luis; Obelleiro, Fernando

in Medical & Biological Engineering & Computing (1999), 37(5), 612-617

The design of a hyperthermia applicator for heating biological tissues is presented in which the applicator consists of an array antenna surrounded by a perfect electrically conducting reflector. The heat ... [more ▼]

The design of a hyperthermia applicator for heating biological tissues is presented in which the applicator consists of an array antenna surrounded by a perfect electrically conducting reflector. The heat hazard to superficial tissues is reduced by the introduction of a dielectric protecting layer over them. A method of moments formulation is applied to approximate the electric field within the biological medium and a closed form expression is presented for the electromagnetic coupling problem, which enables an optimisation procedure to be performed. The applicator enhances both penetration and focusing: deep tumours, close to the bone region, are heated and the percentage of biologically healthy tissue exposed to a specific absorption rate (SAR) hazard level diminishes by 53.8%. [less ▲]

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See detailCrystallization and preliminary X-ray analysis of a new L-aminopeptidase-D-amidase/D-esterase activated by a Gly-Ser peptide bond hydrolysis.
Bompard-Gilles, C; Villeret, V; Fanuel, L et al

in Acta Crystallographica Section D-Biological Crystallography (1999), 55(Pt 3), 699-701

Ochrobactrum anthropi possesses an L-aminopeptidase (DmpA) also able to act as a D-amidase/D-esterase. DmpA (40 kDa) is activated by auto-catalyzed protein splicing liberating an alpha-amino group ... [more ▼]

Ochrobactrum anthropi possesses an L-aminopeptidase (DmpA) also able to act as a D-amidase/D-esterase. DmpA (40 kDa) is activated by auto-catalyzed protein splicing liberating an alpha-amino group presumably used as a general base in the catalytic mechanism. Two crystal forms were obtained at 294 K in 13-16% PEG 2000 mono-methylether at pH 9.0, adding either 0.2 M magnesium chloride or 1 M lithium chloride. Crystals of the first form belong to the space group C2221 and diffract to 3.0 A resolution, whereas crystals of the second form belong to the space group P21212 and diffract to 2.3 A resolution. Initial screening for heavy-atom derivatives on form II crystals, has led to a well substituted Hg derivative. [less ▲]

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See detailExperimental and theoretical radiative lifetimes, branching fractions and oscillator strengths in Lu II
Quinet, Pascal ULg; Palmeri, P.; Biémont, Emile ULg et al

in Monthly Notices of the Royal Astronomical Society (1999), 307

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See detailThe Indotriradites dolianitii Morphon, a distinctive group of miospore species from the Lower Carboniferous of Gondwana.
Loboziak; Melo, J.H.G.; Playford, G et al

in Review of Palaeobotany and Palynology (1999), 107

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See detailLatest Devonian to Early Carboniferous biostratigraphy of Northern Brazil: an update.
Melo, JHG; Loboziak, S; Streel, Maurice ULg

in Bulletin du Centre de Recherches Elf Exploration Production (1999), 22(1), 13-33

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See detailHypnoanesthesia for endocrine cervical surgery: a statement of practice.
Defechereux, Thierry ULg; Meurisse, Michel ULg; Hamoir, Etienne ULg et al

in Journal of Alternative & Complementary Medicine : Research on Paradigm, Practice, & Policy (1999), 5(6), 509-20

OBJECTIVES: To assess the feasibility of endocrine cervical surgery under hypnoanesthesia as a valuable, safe, efficient, and economic alternative to general anesthesia. METHODS: Between April 1994 and ... [more ▼]

OBJECTIVES: To assess the feasibility of endocrine cervical surgery under hypnoanesthesia as a valuable, safe, efficient, and economic alternative to general anesthesia. METHODS: Between April 1994 and June 1997, 197 thyroidectomies and 21 cervical explorations for hyperparathyroidism were performed under hypnoanesthesia (HYP) using Erikson's method. Operative data and postoperative course of this initial series were compared to a contemporary population of patients (n = 119) clinically similar except that they declined HYP or were judged unsuitable for it, and who were therefore operated on under general anesthesia (GA). RESULTS: The surgeons all reported better operating conditions for cervicotomy using HYP. Conversion from hypnosis to GA was needed in two cases (1%). All patients having HYP reported a pleasant experience and, keeping in mind that the GA group is not a randomly assigned control group, both had significantly less postoperative pain and analgesic use. Hospital stay was also significantly shorter, providing a substantial reduction in the costs of medical care. The postoperative convalescence was significantly improved after HYP and a full return to social or professional activity was significantly quicker. CONCLUSION: From this study, we conclude that HYP is an effective technique for providing relief of intraoperative and postoperative pain in endocrine cervical surgery. The technique results in high patient satisfaction and better surgical convalescence. This technique can therefore be used in most well-chosen patients and reduces the socioeconomic impact of hospitalization. [less ▲]

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See detailSome phase equilibrium constraints on the origin of Proterozoic (massif) anorthosites and related rocks
Longhi, John ULg; Vander Auwera, Jacqueline ULg; Fram, Miranda S. et al

in Journal of Petrology (1999), 40

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See detailBiochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-beta-lactamase IMP-1 produced by Escherichia coli.
Laraki, N.; Franceschini, N.; Rossolini, G. M. et al

in Antimicrobial agents and chemotherapy (1999), 43(4), 902-6

The blaIMP gene coding for the IMP-1 metallo-beta-lactamase produced by a Pseudomonas aeruginosa clinical isolate (isolate 101/1477) was overexpressed via a T7 expression system in Escherichia coli BL21 ... [more ▼]

The blaIMP gene coding for the IMP-1 metallo-beta-lactamase produced by a Pseudomonas aeruginosa clinical isolate (isolate 101/1477) was overexpressed via a T7 expression system in Escherichia coli BL21 (DE3), and its product was purified to homogeneity with a final yield of 35 mg/liter of culture. The structural and functional properties of the enzyme purified from E. coli were identical to those of the enzyme produced by P. aeruginosa. The IMP-1 metallo-beta-lactamase exhibits a broad-spectrum activity profile that includes activity against penicillins, cephalosporins, cephamycins, oxacephamycins, and carbapenems. Only monobactams escape its action. The enzyme activity was inhibited by metal chelators, of which 1,10-o-phenanthroline and dipicolinic acid were the most efficient. Two zinc-binding sites were found. The zinc content of the P. aeruginosa 101/1477 metallo-beta-lactamase was not pH dependent. [less ▲]

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See detailHousekeeping Genes as Internal Standards: Use and Limits
Thellin, Olivier ULg; Zorzi, Willy ULg; Lakaye, Bernard ULg et al

in Journal of Biotechnology (1999), 75(2-3), 291-5

Quantitative studies are commonly realised in the biomedical research to compare RNA expression in different experimental or clinical conditions. These quantifications are performed through their ... [more ▼]

Quantitative studies are commonly realised in the biomedical research to compare RNA expression in different experimental or clinical conditions. These quantifications are performed through their comparison to the expression of the housekeeping gene transcripts like glyceraldehyde-3-phosphate dehydrogenase (G3PDH), albumin, actins, tubulins, cyclophilin, hypoxantine phsophoribosyltransferase (HRPT), L32. 28S, and 18S rRNAs are also used as internal standards. In this paper, it is recalled that the commonly used internal standards can quantitatively vary in response to various factors. Possible variations are illustrated using three experimental examples. Preferred types of internal standards are then proposed for each of these samples and thereafter the general procedure concerning the choice of an internal standard and the way to manage its uses are discussed. [less ▲]

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See detailCD44v6 expression is an independent prognostic factor in node-negative FIGO stage IB cervical carcinoma.
Speiser, P.; KRIDELKA, Frédéric ULg; Tempfer, C. et al

in International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society (1999), 9(2), 160-165

Adhesion molecules such as CD44 play an important role in the metastatic cascade by mediating tumor cell interaction with the endothelium and the subendothelial matrix. As a so-called "lymphocyte homing ... [more ▼]

Adhesion molecules such as CD44 play an important role in the metastatic cascade by mediating tumor cell interaction with the endothelium and the subendothelial matrix. As a so-called "lymphocyte homing receptor," CD44 is physiologically involved in migration of circulating lymphocytes to lymphatic tissue. In the present study, we investigated the expression of CD44v3 and v6 in 237 patients with stage IB, N0 cervical carcinoma by means of immunohistochemistry. These results were correlated with the GOG score and other prognostic variables. Median follow-up was 82.6 months (39-110 months). Thirty-nine patients recurred and 35 died from disease within the observation period. In univariate analysis, the GOG score, histologic subtype, and CD44v6 expression were statistically significant predictors for poor overall survival (OS). In multivariate (Cox regression) analysis, the GOG score (< 40 vs. 40-120, RR: 1.37 (95% CI: 1.10-1.71); 40-120 vs. > 120, RR: 2.23 (95% CI: 1.28-3.88); P = 0.004), histologic subtype (adenosquamous carcinomas) (RR: 4.56 (95% CI: 1.49-13.92), P = 0.007) and CD44v6 expression (RR: 2.42 (95% CI: 1.14-5.10), P = 0.021) were independent predictors for poor OS. The expression of CD44v3 did not correlate with prognosis. Furthermore we found a strong correlation between CD44v6 expression and lymphovascular space invasion (LVSI) (chi2 = 17.01, P = 0.0001). Tumor expansion into the loco-regional lymphatic system is the preferred way of tumor spread in cervical carcinoma. The strong correlation of CD44v6 with LVSI produces a significant degree of suspicion that cervical carcinoma cells expressing CD44v6 could, by mimicking lymphocytes, exploit their pathways. [less ▲]

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See detailShelley in travestie: De vertaalstrijd om 'Alastor'
Steyaert, Kris ULg

in Filter: Tijdschrift over Vertalen (1999), 6(3), 28-36

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See detailLe traitement des ectasies anevrysmales de l'aorte ascendante par l'intervention de Robicsek
RADERMECKER, Marc ULg; Laurent, S.; Limet, Raymond ULg

in Revue Médicale de Liège (1999), 54(11), 886-8

The technique and the results of the external contention of the dilated ascending aorta by the application of an external Dacron graft are reported. This technique, without replacing the usual graft ... [more ▼]

The technique and the results of the external contention of the dilated ascending aorta by the application of an external Dacron graft are reported. This technique, without replacing the usual graft interposition, can efficiently and expeditiously treat borderline dilatation of the ascending aorta, as frequently encountered in aortic valve disease. If the sinotubular junction is not dilated, this technique may stop the aneurysmal evolution of the ascending aorta. [less ▲]

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See detailSur philellên chez Cicéron
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1999), 68

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See detailModélisation spatiale de la sélection de l'habitat chez le Blaireau européen (Meles meles) au moyen d'un Système d'Information Géographique.
Vanhalle, L.; Defourny, P.; Dufrêne, Marc ULg

in Cahiers des Réserves Naturelles -Rnob (1999), 13

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See detailSeparation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using nonaqueous electrolytes.
Fillet, Marianne ULg; Bechet, Isabelle; Piette, Véronique et al

in Electrophoresis (1999), 20(9), 1907-15

The aim of the present work was to investigate the separation of nonsteroidal anti-inflammatory drugs (NSAIDs: niflumic acid, flufenamic acid, piroxicam, alclofenac, tiaprofenic acid, flurbiprofen ... [more ▼]

The aim of the present work was to investigate the separation of nonsteroidal anti-inflammatory drugs (NSAIDs: niflumic acid, flufenamic acid, piroxicam, alclofenac, tiaprofenic acid, flurbiprofen, suprofen, ketoprofen, naproxen, indomethacin, carprofen, indoprofen, sulindac) in capillary electrophoresis (CE) using completely nonaqueous systems. The influence of different parameters such as nature and proportion of organic solvent (methanol, acetonitrile, 2-propanol), apparent pH (ranging from 7 to 9) and temperature (ranging from 25 to 40 degrees C) on selectivity and migration times were studied systematically in an uncoated fused-silica capillary. A nonaqueous electrolyte made of 50 mM ammonium acetate - 13.75 mM ammonia in methanol proved to resolve 11 NSAIDs at 25 degrees C and 13 NSAIDs at 36 degrees C, both within 13 min and without a modifier besides the methanol itself. The same buffer containing 30% acetonitrile provides a satisfactory separation for 13 NSAIDs within 14 min at 25 degrees C. [less ▲]

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See detailEffects on nicotine administered via a transdermal delivery system on vigilance : a repeated measure study
Mancuso, Giovanna; Andrès Bénito, Pilar; Ansseau, Marc ULg et al

in Psychopharmacology (1999), 142(1), 18-23

Tested 15 male smokers (aged 18-25 yrs) in a within-Ss design to determine the influence of a transdermal patch of 21 mg nicotine on vigilance. Ss were tested on the Rapid Visual Information Processing ... [more ▼]

Tested 15 male smokers (aged 18-25 yrs) in a within-Ss design to determine the influence of a transdermal patch of 21 mg nicotine on vigilance. Ss were tested on the Rapid Visual Information Processing test 1.3, 3 and 6.3 hrs after patch application, to verify the involvement of the dose of nicotine on the performance. The results confirm and extend the knowledge on the increasing effects of nicotine on vigilance previously found with orally and transdermally administered nicotine. Moreover, results show that such performance was independent of the time of nicotine absorption, which suggests that a relatively low dose of nicotine suffices to activate vigilance processing. Regarding motor performance, no convincing effect of nicotine was observed on reaction time. ((c) 1999 APA/PsycINFO, all rights reserved) [less ▲]

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See detailAccumulation of glycosidically bound compounds in Fragaria * ananassa cv. Elsanta fruits at various developmental stages.
Groyne, Joëlle; Lognay, Georges ULg; Marlier, Michel

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1999), 3(1), 5-9

Isolation of glycosidically bound compounds of Fragaria ´ ananassa cv. Elsanta was performed by Amberlite XAD-2 adsorption followed by methanol elution. After glycosidic extract hydrolysis with a ... [more ▼]

Isolation of glycosidically bound compounds of Fragaria ´ ananassa cv. Elsanta was performed by Amberlite XAD-2 adsorption followed by methanol elution. After glycosidic extract hydrolysis with a commercial b-glucosidase and liquidliquid extraction with diethyl ether, on-line coupled capillary gas chromatographic - mass spectrometric (HRGC-MS) identification of the liberated aglycons was achieved. Five developmental stages of strawberry fruit were investigated during ripening. The occurrence and accumulation of glycosides were pointed out and several aglycons were identified in relation with the investigated developmental stages, with a maximum for the overripe fruit. [less ▲]

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See detailEletriptan: a viewpoint
Schoenen, Jean ULg

in CNS Drugs (1999), 12(4), 334-335

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See detailLe langage à l'envers
Steinmetz, Rudy ULg

in Louvain : Revue Mensuelle de l'Université Catholique de Louvain et de l'Association des Anciens et Amis de l'UCL (1999)

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See detailFormation documentaire et projets pédagogiques
Pochet, Bernard ULg; Thirion, Paul ULg

in Bulletin des Bibliothèques de France (1999), 44(1), 16-22

This article is the fruit of a reflective study carried out over ten years by the group Formation des utilisateurs de l'Association belge de documentation. After a description of «the informational space» ... [more ▼]

This article is the fruit of a reflective study carried out over ten years by the group Formation des utilisateurs de l'Association belge de documentation. After a description of «the informational space» offered by this group and without forgetting the place of the Internet, it offers an outline proposal on general documentation training, largely methodological and integrated in pedagogical projects. Information literacy includes aspects as varied as taking account and expression of information needs, the knowledge of the space of information, the criticism and evaluation of information, and its exploitation... It concludes with the need to construct a solid pedagogical project and with a call to all documentation professionals. [less ▲]

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See detailNondispersive two-electron wave packets in the collinear driven helium atom
Schlagheck, Peter ULg; Buchleitner, A.

in Europhysics Letters [=EPL] (1999), 46(1), 24-30

Nondispersive two-electron wave packets are found in the Floquet spectrum of the driven, one-dimensional helium atom. In classical phase space, they are anchored to the principal nonlinear resonance ... [more ▼]

Nondispersive two-electron wave packets are found in the Floquet spectrum of the driven, one-dimensional helium atom. In classical phase space, they are anchored to the principal nonlinear resonance between the collinear frozen planet orbit and the driving field linearly polarized along the orbit. These novel, highly correlated eigenstates of the driven three-body Coulomb problem, exhibit lifetimes of the order of 10(3)...10(7) periods of the driving field, with strong fluctuations reminiscent of chaos-assisted tunneling. [less ▲]

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See detailMise au point d'un test d'évaluation gestuelle du patient lombalgique
Vanderthommen, Marc ULg; DEFAWEUX, Michel ULg; TOMASELLA, Marco ULg et al

in Revue de la Société Belge des Ecoles du Dos (1999)

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See detailL'art et la ville
Duchesne, Jean-Patrick ULg

in Art&fact (1999), 19

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See detailL'esthéticien
Steinmetz, Rudy ULg

in Art&Fact (1999)

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See detailHas disinfection of endoscopes by automatic machines become obligatory?
Delwaide, Jean ULg; Pelckmans, P.; Defrance, P. et al

in Revue Médicale de Bruxelles (1999), 20(1), 49-50

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See detailEffects of exercise on concentrations of immunoreactive endothelin in bronchoalveolar lavage fluid of normal horses and horses with chronic obstructive pulmonary disease
Benamou, A. E.; Art, Tatiana ULg; Marlin, David J et al

in Equine Veterinary Journal. Supplement (1999), 30

Chronic obstructive pulmonary disease (COPD) represents a major cause of loss of performance in the horse. The role of endothelin (ET), a potent bronchoconstrictive and vasoactive peptide, is currently ... [more ▼]

Chronic obstructive pulmonary disease (COPD) represents a major cause of loss of performance in the horse. The role of endothelin (ET), a potent bronchoconstrictive and vasoactive peptide, is currently being investigated in asthma and other obstructive respiratory diseases in man. We have previously found elevated systemic and pulmonary endothelin levels in horses during exacerbation of COPD. In the present study, our aim was to examine possible variations in ET concentrations occurring during exercise in COPD horses. We compared the effects of intense treadmill exercise on the recovery of endothelin (ET) in the bronchoalveolar lavage fluid (BALF) as well as in arterial and venous blood, in a group of 5 healthy horses and a group of 5 COPD horses studied alternately in remission and while symptomatic. We also investigated the possible correlations between ET levels and pulmonary function tests during the study. While exercise did not affect the ET levels recovered in BALF among controls, it caused a significant increase (P = 0.02) among symptomatic COPD horses. During remission, wide variations of ET levels among horses, at rest and during exercise, made any significant interpretation difficult. No correlation could be found between exercise-induced changes in ET concentrations and pulmonary function tests or changes in arterial oxygen tension with exercise. We conclude that exercise appears to affect the release of ET by the airways in COPD horses, in contrast to healthy horses. It is still unclear, however, whether these differences relate to adjustments of lung function during exercise. [less ▲]

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See detailHuman Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene.
Colige, Alain ULg; Sieron, A. L.; Li, S. W. et al

in American Journal of Human Genetics (1999), 65(2), 308-17

Ehlers-Danlos syndrome (EDS) type VIIC is a recessively inherited connective-tissue disorder, characterized by extreme skin fragility, characteristic facies, joint laxity, droopy skin, umbilical hernia ... [more ▼]

Ehlers-Danlos syndrome (EDS) type VIIC is a recessively inherited connective-tissue disorder, characterized by extreme skin fragility, characteristic facies, joint laxity, droopy skin, umbilical hernia, and blue sclera. Like the animal model dermatosparaxis, EDS type VIIC results from the absence of activity of procollagen I N-proteinase (pNPI), the enzyme that excises the N-propeptide of type I and type II procollagens. The pNPI enzyme is a metalloproteinase containing properdin repeats and a cysteine-rich domain with similarities to the disintegrin domain of reprolysins. We used bovine cDNA to isolate human pNPI. The human enzyme exists in two forms: a long version similar to the bovine enzyme and a short version that contains the Zn++-binding catalytic site but lacks the entire C-terminal domain in which the properdin repeats are located. We have identified the mutations that cause EDS type VIIC in the six known affected human individuals and also in one strain of dermatosparactic calf. Five of the individuals with EDS type VIIC were homozygous for a C-->T transition that results in a premature termination codon, Q225X. Four of these five patients were homozygous at three downstream polymorphic sites. The sixth patient was homozygous for a different transition that results in a premature termination codon, W795X. In the dermatosparactic calf, the mutation is a 17-bp deletion that changes the reading frame of the message. These data provide direct evidence that EDS type VIIC and dermatosparaxis result from mutations in the pNPI gene. [less ▲]

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See detailYeast species for biocontrol of apple postharvest diseases: an encouraging case of study for practical use
Jijakli, Haissam ULg; Grevesse, Cathy; Lepoivre, Philippe ULg

in biotechnological approaches in biocontrol of plant pathogens (1999)

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See detailInfluence function and efficiency of the minimum covariance determinant scatter matrix estimator
Croux, C.; Haesbroeck, Gentiane ULg

in Journal of Multivariate Analysis (1999), 71(2), 161-190

The minimum covariance determinant (MCD) scatter estimator is a highly robust estimator for the dispersion matrix of a multivariate, elliptically symmetric distribution. It is relatively fast to compute ... [more ▼]

The minimum covariance determinant (MCD) scatter estimator is a highly robust estimator for the dispersion matrix of a multivariate, elliptically symmetric distribution. It is relatively fast to compute and intuitively appealing. In this note we derive its influence function and compute the asymptotic variances of its elements. A comparison with the one step reweighted MCD and with S-estimators is made. Also finite-sample results are reported. (C) 1999 Academic Press AMS 1991 subject classifications: 62F35, 62G35. [less ▲]

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See detailCompte rendu de R. AMIET, Les manuscrits liturgiques de Lyon, 1998
George, Philippe ULg

in Scriptorium (1999)

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See detailLicéité des baux au regard de la police de l'aménagement du territoire et de l'urbanisme
Delnoy, Michel ULg

in Actualités Juridiques des Baux (1999)

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See detailAnalysing financial returns using regression models based on non-symmetric stable distributions
Lambert, Philippe ULg; Lindsey, James ULg

in Journal of the Royal Statistical Society : Series C (Applied Statistics) (1999), 48

The daily evolution of the price of Abbey National shares over a 10-week period is analysed by using regression models based on possibly non-symmetric stable distributions. These distributions, which are ... [more ▼]

The daily evolution of the price of Abbey National shares over a 10-week period is analysed by using regression models based on possibly non-symmetric stable distributions. These distributions, which are only known through their characteristic function, can be used in practice for interactive modelling of heavy-tailed processes. A regression model for the location parameter is proposed and shown to induce a similar model for the mode. Finally, regression models for the other three parameters of the stable distribution are introduced. The model found to fit best allows the skewness of the distribution, rather than the location or scale parameters, to vary over time. The most likely share return is thus changing over time although the region where most returns are observed is stationary. [less ▲]

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See detailS/SL/PPV : le prix de l'information du futur
Jérôme, Simone

in Cahiers de la Documentation = Bladen voor Documentatie (1999), (1), 3-25

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See detailAn Evolutive Software Environment for Teaching the Finite Element Method in Electromagnetism
Dular, Patrick ULg; Geuzaine, Christophe ULg; Genon, André ULg et al

in IEEE Transactions on Magnetics (1999), 35(3), 1682--1685

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See detailLymphocytic colitis: a distinct clinical entity? A clinicopathological confrontation of lymphocytic and collagenous colitis.
Baert, F.; Wouters, K.; D'Haens, G. et al

in Gut (1999), 45(3), 375-81

BACKGROUND AND AIMS: It is not known whether lymphocytic colitis and collagenous colitis represent different clinical entities or constitute part of a spectrum of disease. METHODS: Detailed clinical ... [more ▼]

BACKGROUND AND AIMS: It is not known whether lymphocytic colitis and collagenous colitis represent different clinical entities or constitute part of a spectrum of disease. METHODS: Detailed clinical features and histological findings were compared in a large series of patients with confirmed lymphocytic and collagenous colitis. RESULTS: Histological diagnosis was confirmed in 96 patients with collagenous colitis and 80 with lymphocytic colitis. Twenty eight per cent of patients with collagenous colitis and 26% of patients with lymphocytic colitis had overlapping but less pronounced histological features. Both groups were equal in terms of age, use of aspirin and non-steroidal anti-inflammatory drugs, associated autoimmune conditions, arthritis, diarrhoea, and abdominal pain. The male:female ratio was 27:73 for collagenous colitis and 45:55 for lymphocytic colitis (p=0.013). Twenty five per cent of patients with collagenous colitis compared with 14% of patients with lymphocytic colitis were active smokers; only 8.3% of patients with collagenous colitis had stopped smoking compared with 23% of patients with lymphocytic colitis (p=0.013). Drug induced disease was suspected for ticlopidine (two collagenous colitis, four lymphocytic colitis) and flutamide (four lymphocytic colitis). Mean duration of symptoms before diagnosis was two months for lymphocytic colitis and four months for collagenous colitis. Overall prognosis was generally mild; 84% of patients with lymphocytic colitis and 74% of patients with collagenous colitis reported resolution or significant improvement (p=0.033). CONCLUSIONS: Collagenous and lymphocytic colitis are similar but not identical. Patients with lymphocytic colitis present somewhat earlier and are less likely to be active smokers. Symptoms are milder and more likely to disappear in lymphocytic colitis. Ticlopidine and flutamide should be added to the list of drugs inducing colitis. [less ▲]

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See detailThe deformation of the Egersund-Ogna anorthosite massif, south Norway: finite-element modelling of diapirism
Barnichon, Jean-Dominique; Havenith, Hans-Balder ULg; Hoffer, Benoit et al

in Tectonophysics (1999), 303(1-4), 109-130

This paper aims at testing the mechanical relevance of the petrological model of anorthosite massif diapiric emplacement. The Egersund-Ogna massif (S. Norway) is of particular interest because recent ... [more ▼]

This paper aims at testing the mechanical relevance of the petrological model of anorthosite massif diapiric emplacement. The Egersund-Ogna massif (S. Norway) is of particular interest because recent petrological and geochronological data constrain the initial geometry, emplacement conditions and timing (about 2 m.y.). The formation of this anorthosite massif is in agreement with the classical petrological model, in which accumulation of plagioclase takes place in a deep-seated magma chamber at the crust-mantle limit, from which masses of plagioclase separate and rise through the lower crust up to the final level of emplacement at mid-crustal depths. The Egersund-Ogna massif also displays a foliated inner margin, in which strain ellipsoids have been reconstructed by investigating at 51 sites the deformation of megacrysts of high-alumina orthopyroxene. Based on these petrological data, a model made up of one rigid layer (upper granitic crust) and three viscous layers (lower part of the granitic crust, noritic lower crust and anorthosite) has been built up. The upper crust behaviour is represented by an elastoplastic law and the viscous layers obey elastic-viscoplastic laws with Newtonian viscosity. An inverse density gradient is considered between the lower crust (d = 3.00) and the anorthosite (d = 2.75), the loading consisting only in gravity. The modelling is carried out under axisymmetrical conditions, using the LAGAMINE finite-element code coupled with an automatic re-meshing algorithm designed to deal with large strains in complex structures. The results show that, from a mechanical point of view, the diapirism model is a robust and consistent assumption for the emplacement of anorthosites, because realistic diapir and rim-syncline shapes are obtained. Moreover, the numerically obtained emplacement time (about 2.5 m.y.) is in agreement with the available geochronological data, and the computed strain field is coherent with field measurements, especially regarding the circumferential extension, which becomes the largest extension strain component in the expansion phase. (C) 1999 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailLa non-observance therapeutique: probleme majeur pour la prevention des maladies cardio-vasculaires.
Scheen, André ULg

in Revue Médicale de Liège (1999), 54(12), 914-20

The prevention of cardiovascular diseases relies upon the correction of risk factors and, more particularly, the optimal management of various metabolic abnormalities such as obesity, dyslipidaemias ... [more ▼]

The prevention of cardiovascular diseases relies upon the correction of risk factors and, more particularly, the optimal management of various metabolic abnormalities such as obesity, dyslipidaemias, diabetes mellitus and arterial hypertension. Such an approach first requires the adherence to life-style habits (healthy diet, physical activity and no smoking) and, in case of failure, the use of lipid-lowering drugs, antidiabetic agents and/or antihypertensive medications. Sometimes, a monotherapy may be sufficient but, in most cases, a drug combination is mandatory because of the need to reach tight therapeutic targets and of the presence of a polypathology, especially within the frame of the metabolic syndrome. Unfortunately, all surveys indicate that therapeutic compliance to non-pharmacological advice and even to drug prescriptions is far from being excellent. Such a non-compliance limits the efficacy of the prevention strategies and contributes to markedly increase the cost of metabolic diseases and associated complications. [less ▲]

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See detailLa leçon des choses. Robinson ou la répétition
Durand, Pascal ULg

in Etudes Françaises (1999), 35/1

Roman à ce point connu qu'il n'est plus guère lu, texte tronqué parce que trop réécrit, Robinson Crusoe tire peut-être bien de tout ce que Rousseau appelait son « fatras » l'essentiel de sa signification ... [more ▼]

Roman à ce point connu qu'il n'est plus guère lu, texte tronqué parce que trop réécrit, Robinson Crusoe tire peut-être bien de tout ce que Rousseau appelait son « fatras » l'essentiel de sa signification. Actes rituels, besognes et constructions, plaintes et méditations, prières et prêchi-prêcha font de ce texte un roman de la répétition dans lequel un héros calculateur soumet les objets divers qui l'environnent à une comptabilité compulsive. La leçon des choses est trompeuse : le principe d'utilité qu'elles proclament masque assez mal qu'elles restent prises, aux yeux de Robinson, dans la logique marchande qu'elles semblaient suspendre. [less ▲]

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See detailLes agents antiplaquettaires en chirurgie vasculaire périphérique
VAN DAMME, Hendrik ULg; DAVID, Jean-Louis ULg; Limet, Raymond ULg

in Revue Médicale de Liège (1999), 54(2), 109-17

Prescription of platelet inhibitors after arterial surgery is common use. The major concern of the vascular surgeon is to maintain patency of arterial reconstructions. Major causes of graft failure or ... [more ▼]

Prescription of platelet inhibitors after arterial surgery is common use. The major concern of the vascular surgeon is to maintain patency of arterial reconstructions. Major causes of graft failure or arterial thrombosis are the non-thromboresistant nature of the grafts and of the endarterectomised or balloon-dilated surfaces, restenosis due to intimal hyperplasia and progression of atherosclerotic disease in in- or outflow vessels. Platelet adhesion and intimal injury are the primary causes in both processes of graft thrombosis and intimal hyperplasia. To understand how antiplatelet drugs can interfere with these processes, a brief review of platelet function, and of the main platelet inhibitors (aspirin, dypiridamole, ticlopidine) is given. The pathophysiology of intimal hyperplasia is discussed. From clinical trials of peripheral vascular surgery or percutaneous transluminal angioplasty with or without periprocedural antiplatelet therapy, it appears that platelet inhibitors reduce early failure rate by 50% (thrombosis rate at one year reduced from 40 to 20%). There is also evidence that antiplatelet drugs allow to slow down the progression of the atherosclerotic degenerative process in the outflow vessels and in other vascular territories. For the polyvascular patients with charged passed history, platelet inhibitors reduce the risk of myocardial or cerebral infarction by 30% (secondary prevention). Today, there is a general consensus that antiplatelet drugs, started the day before the procedure, are beneficial for early and late patency of peripheral vascular reconstructions (carotid endarterectomy, infrainguinal bypass grafts or endovascular procedures). [less ▲]

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See detailThe influence of tissular cross-talking on osteoarthritis progression: role of non steroidal antiinflammatory drugs
Pelletier, JP; Reginster, Jean-Yves ULg

in Osteoarthritis and Cartilage (1999), 7

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See detailFlow cytometry estimation of nuclear size and ploidy level of habituated calli of sugar beet
Kevers, Claire ULg; Greimers, Roland ULg; Franck, Thierry ULg et al

in Biologia Plantarum (1999), 42(3), 321-332

A fully habituated (auxin- and cytokinin-independent) self-regenerating (organogenic) sugar beet cell line (HO) and a fully habituated non-organogenic one (HNO) derived from the former one, were analyzed ... [more ▼]

A fully habituated (auxin- and cytokinin-independent) self-regenerating (organogenic) sugar beet cell line (HO) and a fully habituated non-organogenic one (HNO) derived from the former one, were analyzed as to their nuclear size and DNA content. Flow cytometry and image analysis were used and cells of certified diploid leaves of the same sugar beet strain served as controls. The HNO cells had been shown previously to have many characteristics of cancerous cells. The analyses made on leaves and HNO cells indicated the presence of only one population of cycling cells. In HO cells. two cycling populations were detected: the first one had the same DNA content as the leaves while the second one contained two fold more DNA than the first population. HNO cells showed the higher nuclear size and DNA content. HNO cells also showed evidence of aneuploidy. Thus, nuclear size, DNA content and ploidy level increase together with the neoplasic progression to culminate in HNO cells with the loss of organogenic totipotency. [less ▲]

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See detailEffective resolution of racemic pirlindole at the preparative scale
De Tullio, Pascal ULg; Ceccato, A.; Liégeois, Jean-François ULg et al

in Chirality (1999), 11

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See detailModelling the propagation pathway of street-traffic noise : practical comparison of German guidelines and real-world measurements
Wetzel, Edgar; Nicolas, Jacques ULg; Andre, Philippe ULg et al

in Applied Acoustics (1999), 57(2), 97-107

In Germany, several guidelines were developed to model the noise propagation pathway. The study compares the guidelines DIN 18005, RLS-90 and VDI 2714, all of which provide some kind of sound object line ... [more ▼]

In Germany, several guidelines were developed to model the noise propagation pathway. The study compares the guidelines DIN 18005, RLS-90 and VDI 2714, all of which provide some kind of sound object line source suited to model street traffic noise. Differences between those guidelines are explained, and their effect on practical calculations is shown in a real-world situation, National Road N4, in Arlon, Belgium. Calculated results are compared to measurements made on critical points along the road. The paper emphasises the understanding of the inner workings of models. In order to avoid differences in calculated results due to software design methods applied, all calculations are made using one single commercially available simulation program. Additionally, this allows for a test of guideline sensitivity to changes in input parameters. [less ▲]

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See detailThe mouse SHIP2 (Inppl1) gene: complementary DNA, genomic structure, promoter analysis, and gene expression in the embryo and adult mouse
Schurmans, Stéphane ULg; Carrio, R.; Behrens, J. et al

in Genomics (1999), 62

SHIP2 is a new member of the inositol polyphosphate 5-phosphatase family showing homology to SHIP1. The structure of both enzymes is characterized by the presence of a 5' SH2 domain, a central catalytic ... [more ▼]

SHIP2 is a new member of the inositol polyphosphate 5-phosphatase family showing homology to SHIP1. The structure of both enzymes is characterized by the presence of a 5' SH2 domain, a central catalytic domain, and a 3' proline-rich region. Recent results suggest that SHIP2 and SHIP1 act downstream of various receptors by removing a phosphate from the 5' position of the phosphatidylinositol 3'-kinase phosphatidylinositol 3,4, 5-triphosphate product and of inositol 1,3,4,5-tetrakisphosphate. Human SHIP2 is highly expressed in adult heart, skeletal muscle, and placenta, whereas SHIP1 expression is limited to the hematopoietic system. We report here the molecular analysis of the mouse SHIP2 cDNA and the corresponding protein, the structure of the gene, and the identification of its promoter. SHIP2 mRNA expression was analyzed in embryonic and adult mouse tissues by reverse transcription-polymerase chain reaction and in situ hybridization. In embryonic day 15.5 mice, SHIP2 was strongly expressed in the liver, specific regions of the central nervous system, the thymus, the lung, and the cartilage perichondrium. In adult mice, SHIP2 mRNA was markedly present in the brain and the thymus and at different stages of spermatozoa maturation in the seminiferous tubules. The subtle differences in the protein structure of SHIP2 and SHIP1 as well as their different patterns of expression are discussed [less ▲]

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See detailOptimal acquisition of video images in reflected light microscopy
Pirard, Eric ULg; Lebrun, Vincent; Nivart, Jean-François

in European Microscopy and Analysis (1999), 60(9-11),

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See detailIncreased number of hip fractures.
Gillet, Pierre ULg; Reginster, Jean-Yves ULg

in Lancet (1999), 353(9170), 2160-1

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