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See detailHumanitarian aid and health services in Eastern Kivu, Zaïre: collaboration or competition
Goyens, Philippe; Porignon, Denis ULg; Mugisho Soron'Gane, Etienne et al

in Journal of Refugee Studies (1996), 9(3), 268-280

The population of eastern Kivu, like that of Rwanda, has been surviving in critical conditions for many years. The Rwandan refugees of 1994 fled into an area with its own serious problems. The Zairean ... [more ▼]

The population of eastern Kivu, like that of Rwanda, has been surviving in critical conditions for many years. The Rwandan refugees of 1994 fled into an area with its own serious problems. The Zairean health services in the health districts of Rutshuru, Kirotshe and Masisi, in spite of the political and socioeconomic disintegration of the country, were still functioning, and the local hospitals and health centres, although overwhelmed, contributed to a large extent to the disaster response. Prominent among the major problems facing the local health services were their limited adaptability, the inadequate coordination and collaboration offered to them by the humanitarian aid agencies, and the discrimination between the direct and secondary victims of the emergency. The public health consequences of the Rwandan refugee crisis for the Zairean population constitute an integral part of the disaster. [less ▲]

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See detailQuelques documents inédits relatifs à Guillaume Lekeu
Pirenne, Christophe ULg; Dado, Stéphane; Verdebout, Luc

in Revue de la Société liégeoise de Musicologie (1996), 5

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See detailRelationships between growth, cannibalism and survival rate in intensively cultured larvae and alevins of perch (Perca fluviatilis)
Mélard, Charles ULg; Baras, E.; Mary, L. et al

in Annales Zoologici Fennici (1996), 33

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See detailSulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons.
Seutin, Vincent ULg; Shen, K. Z.; North, R. A. et al

in Neuroscience (1996), 71(3), 709-19

In Parkinson's disease, there is evidence of impaired mitochondrial function which reduces the capacity to synthesize ATP in dopamine neurons. This would be expected to reduce the activity of the sodium ... [more ▼]

In Parkinson's disease, there is evidence of impaired mitochondrial function which reduces the capacity to synthesize ATP in dopamine neurons. This would be expected to reduce the activity of the sodium pump (Na+/K+ ATPase), causing increased intracellular levels of Na+. Patch pipettes were used to introduce Na+ (40 mM in pipette solutions) into dopamine neurons in the rat midbrain slice in order to study the electrophysiological effects of increased intracellular Na+. We found that intracellular Na+ loading evoked 100-300 pA of outward current (at -60 mV) and increased whole-cell conductance; these effects developed gradually during the first 10 min after rupture of the membrane patch. Extracellular Ba2+ reduced most of the outward current evoked by Na+ loading; this Ba(2+)-sensitive current reversed direction at the expected reversal potential for K+ (EK), and was also blocked by extracellular tetraethylammonium (30 mM) and intracellular Cs+ (which replaced K+ in pipette solutions). The sulfonylurea drugs glipizide (IC50 = 4.9 nM), tolbutamide (IC50 = 23 microM) and glibenclamide (1 microM) were as effective as 300 microM Ba2+ in reducing the K+ current evoked by Na+ loading. When recording with "control" pipettes containing 15 mM Na+, diazoxide (300 microM) increased chord conductance and evoked outward current at -60 mV, which also reversed direction near EK. Effects of diazoxide were blocked by glibenclamide (1 microM) or glipizide (300 nM). Diazoxide (300 microM) and baclofen (3 microM), which also evoked K(+)-mediated outward currents recorded with control pipettes, caused little additional increases in outward currents during Na+ loading. Raising ATP concentrations to 10 mM in pipette solutions failed to significantly reduce currents evoked by diazoxide or Na+ loading, suggesting that these currents may not be mediated by ATP-sensitive K+ channels. Finally, Na+ loading using pipettes containing Cs+ in place of K+ evoked a relatively small outward current (50-150 pA at -60 mV), which developed gradually over the first 10 min after rupturing the membrane patch. This current was reduced by dihydro-ouabain (3 microM) and a low extracellular concentration of K+ (0.5 mM instead of 2.5 mM), but was not affected by Ba2+. We conclude that intracellular Na+ loading evokes a current generated by Na+/K+ ATPase in addition to sulfonylurea-sensitive K+ current. This Na(+)-dependent K+ current is unusual in its sensitivity to sulfonylureas, and could protect dopamine neurons against toxic effects of intracellular Na+ accumulation. [less ▲]

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See detailCytochemistry of the tergite epicuticle of Glomeris marginata (Villers) (MYRIAPODA, DIPLOPODA): preliminary experimental results
Compère, Philippe ULg; Defise, Stéphane; Goffinet, Gerhard ULg

in Mémoires du Muséum d'Histoire naturelle (Paris) - Acta Myriapodologica (1996), 169

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See detailLes champs électromagnétiques de faible intensité produisent une vague calcique dans les fibroblastes
Bomans, J.; Lambert, C. A.; Scarpa, B. et al

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1996), 151(3-4), 243-9250-2

Human fibroblasts display a Ca2+ wave after irradiation with an electromagnetic field (EMF) of low intensity (100 to 900 microT) as seen by LASER confocal microscopy and excitation of Fluo 3. The number ... [more ▼]

Human fibroblasts display a Ca2+ wave after irradiation with an electromagnetic field (EMF) of low intensity (100 to 900 microT) as seen by LASER confocal microscopy and excitation of Fluo 3. The number of excited cells is proportional to the intensity of EMF between 100 and 900 microT. Cellular activation by a dialysable serum factor is required to induce the Ca2+ wave. It also depends on extracellular Ca2+ and active tyrosine kinases and phospholipase C gamma. [less ▲]

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See detailNew bisphosphonates for the treatment of osteoporosis : concerns and hopes
Reginster, Jean-Yves ULg

in Revue du Rhumatisme (English ed.) (1996), 63(7-8), 461-464

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See detailLa géographie au service du développement local. Le bilan du Colloque de Liège (16-18 novembre 1995) de l'Association de Géographes Français
Merenne-Schoumaker, Bernadette ULg

in Cahiers de Géographie du Quebec (1996), 40(111), 479-484

Summary of a symposium held in Liege from 16 to 18 November 1996 on the theme of local development

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See detailDoes proliferation status predict radiation response in human tumors?
Coucke, Philippe ULg

in Radiotherapy & Oncology (1996), 40(Supp 1), 55

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See detailMise au point medicale avant gastroplastie: indications et contre-indications.
Scheen, André ULg

in Revue Médicale de Bruxelles (1996), 17(4), 232-5

Because of the common failure of the various medical procedures used for the treatment of morbid obesity, surgeons have searched alternatives among which gastroplasty appears to offer now the best ... [more ▼]

Because of the common failure of the various medical procedures used for the treatment of morbid obesity, surgeons have searched alternatives among which gastroplasty appears to offer now the best efficacy/safety ratio. Such approach has become more and more popular in our country, but success is almost highly variable from patient to patient. A careful medical assessment is necessary before performing gastroplasty. It mainly aims at choosing the appropriate indications (failure of previous well-applied medical therapy, exclusion of any hormonal cause of obesity, presence of complications due to weight excess, ...) and at excluding cardiovascular (unstable coronaropathy, carotid stenosis, ...), digestive (recurrent oesophagitis, ...) or psychiatric contra-indications. Such medical assessment before gastroplasty should allow to increase the success rate and to reduce the incidence of complications after the surgical procedure. [less ▲]

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See detailMaurice Streel, an annotated list of his publications.
Steemans, Philippe ULg; Loboziak, S

in Annales de la Société Géologique de Belgique (1996), 117

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See detailVan zwart beest tot allemansvriend
Spinoy, Erik ULg

in Muziek en woord (1996), 22(257), 2-3

This article strives to explain the striking evolution in the reception of Van Ostaijen's oeuvre: in his early years, he was a marginalized author. Nowadays, he is one of the most popular and highly ... [more ▼]

This article strives to explain the striking evolution in the reception of Van Ostaijen's oeuvre: in his early years, he was a marginalized author. Nowadays, he is one of the most popular and highly appreciated Flemish authors. [less ▲]

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See detailOccurrence and impact of Heteropolaria (Protozoa: Ciliophora), on intensively cultured perch Perca fluviatilis
Grignard, J. C.; Mélard, Charles ULg; Baras, E. et al

in Annales Zoologici Fennici (1996), 33

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See detailCompte-rendu de l'ouvrage de Doyne Dawson : Cities of the Gods : Communist Utopias in Greek Thought
Vanhaegendoren, Koen ULg

in Etudes Classiques (Namur, Belgium) (1996), 64

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See detailIn Vitro Cytotoxic Activity of Two Potential Anticancer Drugs Isolated from Strychnos: Strychnopentamine and Usambarensine
Bonjean, K. A.; De Pauw-Gillet, Marie-Claire ULg; Quetin-Leclercq, J. et al

in Anticancer Research (1996), 16(3A, May-Jun), 1129-37

The cytotoxicity and the selective antiprotozoal activity of some Strychnos alkaloids, namely strychnopentamine (SP) and usambarensine (US) (7) led us to analyze and compare their effects with emetine (EM ... [more ▼]

The cytotoxicity and the selective antiprotozoal activity of some Strychnos alkaloids, namely strychnopentamine (SP) and usambarensine (US) (7) led us to analyze and compare their effects with emetine (EM) by using mouse B16 melanoma cells cultivated in vitro. We observed by cytological analysis and proliferation rate studies that these substances induce analogous cytotoxic effects in B16 cells, but at different concentrations i.e. formation of lamellar bodies in the cytoplasm, the which contain pre-melanosomes in the case of SP and US, vacuoles and blebs. At concentrations near their respective IC50, SP and US, but not EM, decreased colony formation. We showed by incorporation of labelled precursors that SP and US first inhibit RNA synthesis while EM initially acts on protein synthesis. These alkaloids increased melanin synthesis. Furthermore, only EM and SP caused hemolysis of sheep red blood corpuscles. This could explain why the rate of antiplasmodial activity is higher for SP and EM. [less ▲]

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See detailA propos d'un syndrome de Cushing d'origine indéterminée
Geenen, Vincent ULg

in Actualité Médicale Belge (1996), 513

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See detailMarginalia Vergiliana
Rochette, Bruno ULg

in Zeitschrift für Papyrologie und Epigraphik (1996), 114

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See detailPapyrologica bilinguia Graeco-latina
Rochette, Bruno ULg

in Aegyptus (1996), 76

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See detailSeabirds mortality during the 1992-1993 winter along the Belgian coast
Jauniaux, Thierry ULg; Brosens, L.; Farnir, Frédéric ULg et al

in Annales de Médecine Vétérinaire (1996), 140(3), 149-

During the 1992-1993 133 seabirds found on Belgian beaches were necropsied. Most frequent species were the guillemot (Uria aalge), the oystercatcher (Haematopus ostralegus), the kittiwake (Rissa ... [more ▼]

During the 1992-1993 133 seabirds found on Belgian beaches were necropsied. Most frequent species were the guillemot (Uria aalge), the oystercatcher (Haematopus ostralegus), the kittiwake (Rissa tridactyla), the razorbill (Alca torda) and the herring gull (Larus argentatus). The three main observations were, in decreasing order, cachexia, acute and hemorrhagic gastroenteritis, and oil contamination of plumage and intestinal tract. The pelagic origin of seabirds was associated with all 3 observations; oil contamination was associated with acute gastro-enteritis and cachexia and, finally, the immature character was associated with cachexia. A hypothetical mechanism of death would be oiled pelagic seabirds that become cachectic and die of acute gastroenteritis. It is unlikely that seabirds act as a reservoir for bacteria, that were only occasionally identified in our material. Therefore, it appears that infectious agents play a minor role in seabirds stranding. [less ▲]

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See detailChronique de criminologie: Quels supporters pour l'an 2000?
Kellens, Georges ULg; Comeron, Manuel ULg

in Revue de Droit Pénal et de Criminologie (1996), (3), 306-312

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See detailBessy & Chateauraynaud : Experts et faussaires
Melard, François ULg

in Recherches sociologiques (1996), 2

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See detailAnalysis of structural members under elevated temperature conditions- Discussion
Franssen, Jean-Marc ULg

in Journal of Structural Engineering (1996), 10

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See detailL’expérience du SEGEFA en géographie appliquée
Merenne-Schoumaker, Bernadette ULg

in Géographes Associés (1996), (19), 25-29

Presentation and critical analysis of the experience in applied geography SEGEF

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See detailRuminal, cardiorespiratory and adrenocortical sequelae of Na2EDTA-induced hypocalcemia in calves
Desmecht, Daniel ULg; Linden, Annick ULg; Lekeux, Pierre ULg

in Veterinary Research Communications (1996), 20

A study was undertaken to provide further information on the ruminal, cardiorespiratory and hypothalamo-pituitary-adrenocortical (HPAC) physiological sequelae of hypocalcaemia in dairy calves. The ... [more ▼]

A study was undertaken to provide further information on the ruminal, cardiorespiratory and hypothalamo-pituitary-adrenocortical (HPAC) physiological sequelae of hypocalcaemia in dairy calves. The functional picture observed in standing calves experiencing Na2EDTA-induced progressive hypocalcaemia showed a biphasic pattern. During the first phase (Ca2+ varying between 1.20 +/- 0.09 and 0.64 +/- 0.15 mmol/L, mean +/- SD), the animals became dull and lethargic, shifting their weight from one hind limb to the other, with cool extremities and hypersalivation. Their ventilation was slightly increased but their heart rate, thoracoabdominal pressure, pulmonary mechanics, haemoglobin and temperature remained constant. Conversely, their systemic arterial pressure (SAP) and the amplitude of their ruminal contractions (RCA) were severely decreased. During the second phase (Ca2+ < 0.64 +/- 0.15 mmol/L), there was restlessness, tachycardia, hypertension, polycythaemia and, finally, inability to stay upright. It is suggested that the diminished Ca2+ availability caused smooth-muscle and myocardial dysfunctions which could explain the RCA and SAP changes recorded during the first phase, whereas neural and/or humoral sympathetic discharge probably accounted for the reversal in SAP and heart rate when Ca2+ was decreased further. Serum cortisol increased regularly and remained significantly correlated with Ca2+ in each animal. Moreover, regression of delta cortisol/delta Ca2+ on delta Ca2+/delta Na2EDTA was significant (p < or = 0.001). It was concluded that mild asymptomatic hypocalcaemia severely impairs ruminal function, which will progressively worsen the Ca2+ deficit; that the inability to maintain posture in hypocalcaemia is not due to hypotension; and that the higher the HPAC response to hypocalcaemia, the higher the resistance to its effects. An asymptomatic periparturient cow with barely detectable ruminal activity may merit preventive calcium borogluconate therapy. Also, the physiological role of hypotension in explaining the clinical picture may be less important than other processes, such as neuromuscular failure. Finally, the present results imply a possible HPAC exhaustion in cows with periparturient paretic hypocalcaemia [less ▲]

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See detailDeposition in the Distal Parts of the Bovine Respiratory Tract: Assessment of Equipment Suitable for Drug Inhalation
Genicot, Bruno; Votion, Dominique ULg; Munsters, K. et al

in Veterinary Record : Journal of the British Veterinary Association (1996), 138(13), 302-304

The efficiency of equipment suitable for the inhalation of drugs by calves was assessed in six animals which inhaled radioisotopically labelled particles while suffering from reversible diffuse ... [more ▼]

The efficiency of equipment suitable for the inhalation of drugs by calves was assessed in six animals which inhaled radioisotopically labelled particles while suffering from reversible diffuse bronchoconstriction induced experimentally with 5-hydroxytryptamine and while they were breathing normally. Respiratory rates and data from pulmonary function tests and scintiscans were recorded during both investigations. After the first investigation, a mean (se) wash-out period of 9.8 (3.2) days was allowed. Under diffuse bronchoconstriction, the respiratory rate, the oscillatory resistance and the compliance of the respiratory system reached 282.1 (22.0), 161.1 (10.8) and 68.8 (2.7) per cent of their respective baseline values. When the calves were breathing normally these parameters did not change over time. The ratios (Cp/Ct) of the counts of gamma-disintegrations in the peripheral part (Cp) of the lungs and in the total lung area (Ct) were not significantly different when comparing the results from the two investigations. The ratios of Cp/Ct in the left lungs did not differ significantly from those in the right lungs. [less ▲]

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See detailForeword
Fontana, Roberta; Canepari, Pietro; Ghuysen, Jean-Marie ULg

in Microbial Drug Resistance : Mechanism, Epidemiology, & Disease (1996), 2(1), 5-5

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See detailActeurs sociaux et perspectives préventives du hooliganisme: Orientations en guise de conclusions
Kellens, Georges ULg; Comeron, Manuel ULg

in Revue Sport (1996), 1(153), 63-64

Euro 2000: sécurité, stewards, Fan coaching

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See detailGlacial-interglacial variability of atmospheric CO2 due to changing continental silicate rock weathering: A model study
Munhoven, Guy ULg; Francois, Louis ULg

in Journal of Geophysical Research (1996), 101(D16), 21423-21437

An 11-box model of the oceanic carbon cycle including sedimentary processes is used to explore the role chemical weathering of continental silicate rocks might play in driving atmospheric CO2 levels on ... [more ▼]

An 11-box model of the oceanic carbon cycle including sedimentary processes is used to explore the role chemical weathering of continental silicate rocks might play in driving atmospheric CO2 levels on glacial-interglacial timescales. Histories for the consumption of CO2 by silicate rock weathering processes are derived from the marine Ge/Si record. Taking the major uncertainties in the knowledge of the Ge and Si cycles into account, several histories for the evolution of the riverine dissolved silica fluxes are calculated from this record. The investigation of the systematics between riverine dissolved silica and bicarbonate fluxes under different weathering regimes leads us to the tentative conclusion that although there is no correlation between dissolved silica and total bicarbonate concentrations in the major rivers, there may exist a negative correlation between weathering intensity and the ratio of dissolved silica to bicarbonate derived from silicate weathering alone. With this correlation as a working hypothesis, it is possible to interpret the dissolved silica fluxes in terms of equivalent CO2 consumption rates. The calculated histories indicate that glacial rates of CO2 consumption by chemical silicate rock weathering could have been twice, and possibly up to 3.5 times, as high as they are today. When used to force the carbon cycle model, they are responsible for glacial-interglacial pCO2 variations in the atmosphere of typically 50–60 ppm and up to 95–110 ppm. These variations are superimposed to a basic oscillation of 60 ppm generated by the model, mainly in response to coral reef buildup and erosion processes. The total pCO2 signal has an amplitude of about 80–90 ppm and up to 125–135 ppm. Although these large amplitudes indicate that silicate weathering processes should be taken into account when studying glacial-interglacial changes of CO2 in the atmosphere, it also raises new problems, such as too high CO2 levels during the period from 110–70 kyr B.P., requiring further study. [less ▲]

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See detailApproximation of reliability for multiple-trait animal models with missing data by canonical transformation
Gengler, Nicolas ULg; Misztal, I.

in Journal of Dairy Science (1996), 79(2), 317-328

An algorithm for approximation of reliability for multiple traits by multiple diagonalization was modified to support missing data by weighting transformed contributions of records based on the pattern of ... [more ▼]

An algorithm for approximation of reliability for multiple traits by multiple diagonalization was modified to support missing data by weighting transformed contributions of records based on the pattern of missing data. The accuracy of approximation was assessed with simulated and field data by comparing approximate reliabilities with those from direct inversion. Simulated data had several levels of missing data and covariances between traits; correlations were close to those for linear type traits of dairy cattle. Field data were 1) dairy records for milk, fat, and protein yields with 26% of the observations for fat and protein removed and 2) beef records for birth weight, weaning weight, and mean gain after weaning with 43% of observations missing. These files also contained empty fixed effect classes. The algorithm worked best for simulated data, and, when covariances between traits decreased, proportion of missing traits decreased and the number of empty fixed classes decreased. For dairy data, improvement over single-trait reliability occurred only for traits with missing data; for beef data, little or no improvement occurred. The method is useful with multiple diagonalization if the proportion of missing records or number of empty fixed effect classes or covariances between traits is moderate. [less ▲]

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See detailA novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain
Jacquemin, Patrick; Hwang, Jung-Joo; Martial, Joseph ULg et al

in Journal of Biological Chemistry (1996), 271(36), 21775-85

We describe the molecular cloning of two novel human and murine transcription factors containing the TEA/ATTS DNA binding domain and related to transcriptional enhancer factor-1 (TEF-1). These factors ... [more ▼]

We describe the molecular cloning of two novel human and murine transcription factors containing the TEA/ATTS DNA binding domain and related to transcriptional enhancer factor-1 (TEF-1). These factors bind to the consensus TEA/ATTS cognate binding site exemplified by the GT-IIC and Sph enhansons of the SV40 enhancer but differ in their ability to bind cooperatively to tandemly repeated sites. The human TEFs are differentially expressed in cultured cell lines and the mouse (m)TEFs are differentially expressed in embryonic and extra-embryonic tissues in early post-implantation embryos. Strikingly, at later stages of embryogenesis, mTEF-3 is specifically expressed in skeletal muscle precursors, whereas mTEF-1 is expressed not only in developing skeletal muscle but also in the myocardium. Together with previous data, these results point to important, partially redundant, roles for these TEF proteins in myogenesis and cardiogenesis. In addition, mTEF-1 is strongly coexpressed with mTEF-4 in mitotic neuroblasts, while accentuated mTEF-4 expression is also observed in the gut and the nephrogenic region of the kidney. These observations suggest additional roles for the TEF proteins in central nervous system development and organogenesis. [less ▲]

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See detailRemarques sur le bilinguisme gréco-latin
Rochette, Bruno ULg

in Etudes Classiques (Namur, Belgium) (1996), 64

Réflexions sur la coexistence de l'emploi des langues grecque et latine dans le monde méditerranéen antique, ce phénomène étant considéré principalement sous son aspect littéraire, dans une perspective ... [more ▼]

Réflexions sur la coexistence de l'emploi des langues grecque et latine dans le monde méditerranéen antique, ce phénomène étant considéré principalement sous son aspect littéraire, dans une perspective diachronique. Les pionniers de la littérature latine furent des affranchis de langue grecque qui s'exprimaient en latin. Dès la fin du deuxième siècle av. J.-C., même si l'apport des affranchis grecs à l'histoire romaine reste important, de nombreux Romains cultivés s'expriment en grec. Devant les ressources qu'offre la langue grecque, plus d'un auteur latin, jusqu'à la fin de la République, déplore la « patrii sermonis egestas ». Mais Cicéron affirme la richesse du lexique latin et entreprend avec un grand souci d'exactitude des traductions du grec en latin. Finalement, durant toute la période impériale, les deux langues se complètent et s'équilibrent. [less ▲]

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See detailEvaluation of the cranial rectus abdominus muscle pedicle flap as a blood supply for the caudal superficial epigastric skin flaps in dogs.
Degner, Daniel; Walshaw, Richard; Arnoczky, Steven et al

in Veterinary Surgery : The Official Journal of the American College of Veterinary Surgeons (1996), 25

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See detailFinite element modelling of the competition between shear bands in the early stage of thrusting : Strain localisation and constitutive law influence
Barnichon, Jean-Dominique; Charlier, Robert ULg

in Special Publication - Geological Society of London (1996), 99

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See detailEffecten van internationale overnames op aandelenrendementen
Adriaanse, F.; Corhay, Albert ULg; Tourani-Rad, Alireza

in Maandblad voor Accountancy en Bedrijfseconomie [=MAB] (1996), 70(3), 123-132

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See detailControl of chorionic obstructive pulmonary disease in the horse
Lekeux, Pierre ULg; Art, Tatiana ULg; Roberts, C.

in British Veterinary Journal (The) (1996), 152

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See detailEtude dynamographique de la marche de l'hémiplégique: effets de différentes modalités d'électrostimulation
Vanderthommen, Marc ULg; Lucas, C.; Laurent, J.M. et al

in Kine Acta-Symposium (1996)

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See detailAutologous stem cell transplantations in elderly AML patients
Archimbaud, E.; Jehn, U.; De Cataldo, F. et al

in Trends in Onco-Hematology (1996), 4(2), 28-29

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See detailTabac et maladie parodontale
Geerts, Sabine ULg

in Actualités Dentaires de l'Université de Liège (1996), 19

Le tabac est un facteur aggravant la parodontite. Beaucoup d'études cliniques ont été menées et ont souvent montré des résultats contradictoires. Cet article est une revue de littérature sur la relation ... [more ▼]

Le tabac est un facteur aggravant la parodontite. Beaucoup d'études cliniques ont été menées et ont souvent montré des résultats contradictoires. Cet article est une revue de littérature sur la relation entre le tabagisme et la parodontite. [less ▲]

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See detailReconnaissance des malformations et pathologies prénatales du système nerveux central
Misson, Jean-Paul ULg; Dubru, Jean-Marie ULg; Leroy, Patricia

in Acta Paediatrica Belgica (1996), 28(3), 204-215

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See detailAge and correlation of the Barreinrinha Formation (Curua Group, Amazon Basin) : new evidence from the Miospore biostratigraphy
Loboziak, S.; Melo, J.H.G.; Rodriguez, R. et al

in Anais da Academia Brasileira de Ciencias (1996), 68(2), 207-212

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See detailDesign and modeling of new platelet-activating factor antagonists.3. Relative importance of hydrophobicity and electronic distribution in piperazinic series
Heymans, Françoise; Dive, Georges ULg; Lamouri, Aazdine et al

in Journal of Lipid Mediators and Cell Signalling (1996), 15(2), 161-173

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See detailExperimental research on the determination of the main parameters affecting the behaviour of reinforced concrete columns under fire conditions
Dotreppe, Jean-Claude ULg; Franssen, Jean-Marc ULg; Bruls, Alois et al

in Magazine of Concrete Research (1996), 48(6), 117-127

The design of reinforced concrete columns under fire conditions is generally made on the basis of national and international recommendations. The CEB/FIP recommendations have been used for many years ... [more ▼]

The design of reinforced concrete columns under fire conditions is generally made on the basis of national and international recommendations. The CEB/FIP recommendations have been used for many years. Recently, in the framework of the Eurocodes, the document ENV 1992-1-2 (Eurocode 2-1-2), Structural fire design, has been approved by Commission CEN/TC250/SC2 of the European Committee for Standardization. In the CEB/FIP documents and in Eurocode 2-1-2 the main part is devoted to design from tabulated data containing the dimensions of the cross-sections and values for the concrete cover. The use of simplified calculation methods is not current practice for concrete elements, while they are widely used in the case of steel. The determination of the temperature distribution in the cross-section does not facilitate the development of a simplified method. Furthermore, in columns there is a wide scatter of experimental results. In order to gain additional information, an extensive experimental research programme on the behaviour of reinforced concrete columns under fire conditions, financially supported by the Belgian Funds for Fundamental Collective Research (FRFC-FKFO), has been performed at the Universities of Liege and Ghent. In this article the results of this research are presented and the influence of the main parameters is analysed. [less ▲]

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See detailThe Creb, Atf-1, And Atf-2 Transcription Factors From Bovine Leukemia Virus-Infected B Lymphocytes Activate Viral Expression
Adam, E.; Kerkhofs, P.; Mammerickx, M. et al

in Journal of Virology (1996), 70(3),

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See detailEvaluation du débit sanguin au niveau du quadriceps électrostimulé et contracté volontairement
Vanderthommen, Marc ULg; BAUVIR, Philippe ULg; Depresseux, J.C. et al

in Annales de Kinésithérapie (1996), 23(1), 20-23

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See detailParticle Production in a Hadron Collider Rapidity Gap: The Higgs Case
Cudell, Jean-René ULg; Hernandez, Oscar F

in Nucl. Phys. (1996), B471

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See detailBactericidal activity against Pseudomonas aeruginosa is acquired by cultured human monocyte-derived macrophages after uptake of myeloperoxidase.
Mathy-Hartert, M.; Deby, Ginette ULg; Melin, Pierrette ULg et al

in Experientia (1996), 52(2), 167-74

Myeloperoxidase (MPO) is an enzyme located within polymorphonuclear neutrophils capable of producing cytotoxic oxidant species that are particularly active against bacteria with polysaccharide capsules ... [more ▼]

Myeloperoxidase (MPO) is an enzyme located within polymorphonuclear neutrophils capable of producing cytotoxic oxidant species that are particularly active against bacteria with polysaccharide capsules. Pseudomonas aeruginosa (10(6) bacteria per 1ml) are killed within 1 h in vitro by a MPO/H2O2/C1- system (48mU=132ng of MPO). The question arose as to whether human macrophages would acquire cytotoxic activity when loaded with this enzyme. Monocytes were therefore isolated from human blood and cultured for up to ten days to induce maturation to macrophages. These cells lost endogenous MPO within five days while H2O2 production in response to stimulation by phorbol myristate acetate (10(-6)M) decreased to 23% within ten days. On the other hand, their capacity to take up exogenous MPO increased fourfold from day three to day ten. Human macrophages cultured from eight days (when both H2O2 production and MPO uptake were sufficient) were therefore used to study the effects of MPO uptake on cytocidal activity against Pseudomonas aeruginosa. After a 1 h MPO loading period, macrophages (5X10(5) cells per ml) were incubated in the presence of bacteria (0.5 to 2X10(6) bacteria per ml) for 2 h at 37 degrees C. At a bacteria/macrophage ratio of 1, only 34.8+/-7.0% of bacteria survived (compared to killing by non-loaded macrophages), while 74.4+/-9.3% survived at a ratio of 4. From these results, we conclude that loading macrophages with exogenous MPO could enhance their microbicidal activity, suggesting a potentially useful therapeutic application. [less ▲]

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See detailHistorical seismicity of the Strait of Dover–Pas de Calais
Melville, Charles; Levret, Agnès; Alexandre, Pierre ULg et al

in Terra Nova (1996), 8

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See detailMutations structurelles d'emploi et insertion professionnelle
Gavray, Claire ULg

in Lettre d'information TEF (1996), 4

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See detailBrain thiamine, its phosphate esters, and its metabolizing enzymes in Alzheimer's disease.
Mastrogiacomo, Frank; Bettendorff, Lucien ULg; Grisar, Thierry ULg et al

in Annals of Neurology (1996), 39

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See detailA single editing event is a prerequisite for efficient processing of potato mitochondrial phenylalanine tRNA
MarechalDrouard, L.; Cosset, A.; Remacle, Claire ULg et al

in Molecular & Cellular Biology (1996), 16(7), 3504-3510

In bean, potato, and Oenothera plants, the C encoded at position 4 (C-4) in the mitochondrial tRNA(GAA)(Phe) gene is converted into a U in the mature tRNA, This nucleotide change corrects a mismatched C-4 ... [more ▼]

In bean, potato, and Oenothera plants, the C encoded at position 4 (C-4) in the mitochondrial tRNA(GAA)(Phe) gene is converted into a U in the mature tRNA, This nucleotide change corrects a mismatched C-4-A(69) base pair which appears when the gene sequence is folded into the cloverleaf structure. C-to-U conversions constitute the most common editing events occurring in plant mitochondrial mRNAs. While most of these conversions introduce changes in the amino acids specified by the mRNA and appear to be essential for the synthesis of functional proteins in plant mitochondria, the putative role of mitochondrial tRNA editing has not yet been defined. Since the edited form of the tRNA has the correct secondary and tertiary structures compared with the nonedited form, the two main processes which might be affected by a nucleotide conversion are aminoacylation and maturation. To test these possibilities, we determined the aminoacylation properties of unedited and edited potato mitochondrial tRNA(Phe) in vitro transcripts, as well as the processing efficiency of in vitro-synthesized potato mitochondrial tRNA(Phe) precursors. Reverse transcription-PCR amplification of natural precursors followed by cDNA sequencing was also used to investigate the influence of editing on processing. Our results show that C-to-U conversion at position 4 in the potato mitochondrial tRNA(GAA)(Phe) is not required for aminoacylation,vith phenylalanine but is likely to be essential for efficient processing of this tRNA. [less ▲]

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See detailEnhancement of nuclear receptor transcriptional signalling.
Renkawitz, Rainer; Kaltschmidt, Christian; Leers, Joerg et al

in Journal of Steroid Biochemistry & Molecular Biology (1996), 56(1-6 Spec No), 39-45

Glucocorticoids and thyroid hormones induce complex responses in about every mammalian tissue. These effects are mediated by the transcription factor function of the corresponding nuclear receptors, which ... [more ▼]

Glucocorticoids and thyroid hormones induce complex responses in about every mammalian tissue. These effects are mediated by the transcription factor function of the corresponding nuclear receptors, which in most cases achieve the observed regulatory strength in synergy with other factors. Here we describe the functional interaction of the glucocorticoid receptor (GR) with liver-specific transcription factors, the functional synergy of GR with the thyroid hormone receptor (TR), the synergizing sub-domains of the TR, and finally the direct interaction of the GR with other proteins. [less ▲]

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See detailEvaluacion isocinetica de las ligamentoplastias de rodilla
Croisier, Jean-Louis ULg; Villanueva, F. J.; Delcour, J. P. et al

in Utilidad de la reeducacion. Inflamación (1996), 7

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See detailEffects of castration on fear reactions of male sheep.
Vandenheede, Marc ULg; Bouissou, Marie-France

in Applied Animal Behaviour Science (1996), 47

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See detailPaget’s disease of bone : diagnosis and management
Hosking, D; Meunier, PJ; Ringe, JD et al

in British Medical Journal (1996), 312

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See detailLes Charites à Athènes et dans l’île de Cos
Pirenne-Delforge, Vinciane ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (1996), 9

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See detailMagnetic alignment in 2212 Bi-based superconducting system .1. Magnetic orientation of Bi2Sr2Ca1-x(RE)(x)Cu2O8-y [(RE)=Gd, Dy, Ho, Er] powder dispersed in epoxy resin at room temperature
Stassen, S.; Cloots, Rudi ULg; Vanderbemden, Philippe ULg et al

in Journal of Materials Research (1996), 11(5), 1082-1085

The magnetic anisotropy of rare-earth substituted 2212 materials (Bi(2)Sr(2)Ca(0.8)RE(0.2)Cu(2)O(x) with RE = Gd, Dy, Ho, Er) is put into evidence. Superconducting powder dispersed in epoxy resin is ... [more ▼]

The magnetic anisotropy of rare-earth substituted 2212 materials (Bi(2)Sr(2)Ca(0.8)RE(0.2)Cu(2)O(x) with RE = Gd, Dy, Ho, Er) is put into evidence. Superconducting powder dispersed in epoxy resin is oriented under an external magnetic field (4 T) in a direction that depends on the nature of the rare-earth used in the substitution. Both directions of observation (parallel or perpendicular to the field) were investigated. Splitting of (00l) peaks is neatly observed and discussed. [less ▲]

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See detailOrdovician and Silurian cryptospores and miospores from southeastern Turkey
Steemans, Philippe ULg; Le Hérissé, A; Bozdogan, N

in Review of Palaeobotany and Palynology (1996), 93(1-4), 35-76

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See detailCes histoires que l'on construit et que l'on se raconte...
Guillaume, Jean-François ULg

in Cahiers Internationaux de Sociologie (1996), 100

A partir des réflexions de Paul Ricoeur sur la temporalité et la narrativité, l'A. envisage les processus discursifs de construction identitaire chez les jeunes gens en fin de scolarité obligatoire. L ... [more ▼]

A partir des réflexions de Paul Ricoeur sur la temporalité et la narrativité, l'A. envisage les processus discursifs de construction identitaire chez les jeunes gens en fin de scolarité obligatoire. L'identité en construction est appréhendée à travers le récit qu'ils donnent de leurs projets d'avenir et de leur histoire familiale. La présentation de soi, perçue dans cette double dimension, est soumise à un ensemble de schèmes ou de modèles narratifs culturellement ancrés et socialement véhiculés. Elle prend forme et se constitue en une totalité cohérente et intelligible par une « mise en intrigue » de la diversité des péripéties vécues ou imaginées. [less ▲]

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See detailCompte rendu de l'ouvrage de ANDORLINI Isabella (Edizione e commento a cura di), Trattato di medicina su papiro, Firenze, Istituto Papirologico "G. Vitelli", 1995
Marganne, Marie-Hélène ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1996), 71

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See detailLa greffe de cellules souches hematopoietiques (greffe de moelle osseuse"): indications, modalites et risques."
Beguin, Yves ULg

in Revue Médicale de Liège (1996), 51(4), 270-5

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See detailRole of the metallothioneins in metal regulation by the guillemot Uria aalge
Bouquegneau, Jean-Marie ULg; Debacker, Virginie ULg; Gobert, Sylvie ULg et al

in Comparative Biochemistry and Physiology. C : Comparative Pharmacology and Toxicology (1996), 113C(2), 135-139

Guillemots, like other seabird species living in the North Sea, appear to be heavily contaminated by copper. Metallothioneins are present in both liver and kidney but, at least in the specimens stranded ... [more ▼]

Guillemots, like other seabird species living in the North Sea, appear to be heavily contaminated by copper. Metallothioneins are present in both liver and kidney but, at least in the specimens stranded along the Belgian coast, fail to maintain constant the copper, zinc and cadmium load of the high molecular weight soluble proteins of both organs, stressing the potential toxic role of these metals, mainly copper. [less ▲]

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See detailLes "deux cultures" et la tâche de la philosophie
Bouquiaux, Laurence ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (1996)

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See detailRéactions physiologiques face à des conditions extrêmes de chaleur et d'humidité relative: Etude des effets de l'exercice
Art, Tatiana ULg; Lekeux, Pierre ULg

in Pratique Vétérinaire Equine (1996), 28

The purpose of this study was to investigate the effect of a hot and humid environment on the pattern of breathing and the gas exchange in heavily exercising horses. Five healthy fit standardbred horses ... [more ▼]

The purpose of this study was to investigate the effect of a hot and humid environment on the pattern of breathing and the gas exchange in heavily exercising horses. Five healthy fit standardbred horses (493± 14 kg; 4± 0,5yrs) were investigated twice at eight days interval, once in temperated atmos¬pheric conditions (TC) (ambient temperature : 15o C; relative humidity : 55 %) and once in hot and humid conditions (HHC) (ambient temperature : 30°C; relative humidity : 75 %). The standardized treadmill exercise test consisted in 8 min warm-up and in 8 min exer¬cise (1 min at 1,7, 4, 7, 8, 9 and 10 m/sec and 2 min at 4 m/sec with a 6% slope). Respiratory airflow, tidal volume, respiratory frequency as well as the 02 and C02 fraction in the inspired and expired gases were continuously recorded, using 2 ultrasonic pneumo¬tachographs connected to a face mask and a mass spectrometer. Oxygen uptake (VO2, carbon dioxide output (VCO2,), respiratory quotient (RQ) and expired minute volume (VE.) as well as alveolar partial pressure in C02 (PAC02) were obtained on a breath-by--breath basis. The maximal values obtained during the highest intensity were used for the comparison between both tests. Heart rate and skip temperature were continuously recorded, using a heart rate recording system and a real time infrared thermographic unit, respecti¬vely. Venous blood was sampled before and 2 min after the completion of the test for hematological and biochemical analysis, namely plasma lactate (LA), beta-endorphins, cortisol (Cor). Running in HHC induced a significant decrease in peak VE, VO2, VCO2 and oxygen pulse, while RQ remained unchanged and PAC02 increased. The changes in skin temperature (ST), i.e. the difference between ST at rest and at 10 m/sec, was dramatically higher in HHC. As well, the test-induced changes, i.e. the differences between the values before and after the test, in Cor, beta-endorphins and LA values after the test were significantly higher. This study shows that performing a strenuous exercise in hot, humid conditions in unacclimatized horses induced a reduction of the aerobic capacity, i.e. decrease of the VO2 and increase of LA production. A relative hypoventilation could be partly responsible for this observation, but all the steps of the oxygen transport from the pulmonary ventilation to the muscle metabolism could also potentially be impaired in such conditions [less ▲]

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See detailTowards concerted river management in Belgium.
Mormont, Marc ULg

in Journal of Environmental Planning & Management (1996), 39(1), 131-141

River basin management is a highly complex issue, involving scientific uncertainties and competing interests between many groups. One approach is to build consensus between different users and to agree a ... [more ▼]

River basin management is a highly complex issue, involving scientific uncertainties and competing interests between many groups. One approach is to build consensus between different users and to agree a common basis for operation. The King Baudouin Foundation in Belgium has supported the idea of 'river contracts' as a way of producing agreed strategies for river management. Examples of early contracts are described and their wider significance reviewed. [less ▲]

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See detailThe Ahrensburgian site at Zonhoven-Molenheide
Vermeersch, Pierre M.; Peleman, Chris; Rots, Veerle ULg et al

in Notae Praehistoricae (1996), 16

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See detailVers une perspective transactionnelle du stress au travail : pistes d'évaluations méthodologiques
De Keyser, Véronique ULg; Hansez, Isabelle ULg

in Cahiers de Médecine du Travail (1996), 33(3), 133-144

L'objectif principal de cet article est d'élaborer des pistes d'évaluations méthodologiques pour les études sur le stress au travail. L'approche se base sur une définition du stress axée sur le contrôle ... [more ▼]

L'objectif principal de cet article est d'élaborer des pistes d'évaluations méthodologiques pour les études sur le stress au travail. L'approche se base sur une définition du stress axée sur le contrôle de la situation et adopte une conception transactionnelle du stress psychologique au travail insistant sur l'importance de l'évaluation de la situation par l'individu et les processus de coping, dans une perspective diachronique (Mackay et Cooper, 1987). Cet article synthétise les indices utilisés généralement dans les recherches sur le stress au travail et discute leurs limites. Les problèmes méthodologiques envisagés sont les suivants: la difficulté d'établir des relations causales, les problèmes de validité discriminante et convergente, la mise en évidence des effets de chronicité, la fidélité des mesures. Des suggestions sont alors proposées, basées principalement sur une démarche combinant comparaisons intra et inter-individuelles, la méthode des «critical job events» ou approche épidémiologique, les stratégies de triangulation, le tout dans une perspective longitudinale. Pour terminer, des exemples en milieu hospitalier illustrent les démarches proposées. [less ▲]

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See detailEx-vivo cytokine production by whole blood cells from cancer patients
De Groote, Donat; Vrindts-Gevaert, Yvonne; Lopez Y Cadenas, Miguel ULg et al

in Cancer Detection & Prevention (1996), 20

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See detailClay mineral signature of the NW Atlantic Boundary Undercurrent
Fagel, Nathalie ULg; Robert, Christian; Hillaire Marcel

in Marine Geology (1996), 130(1-2), 19-28

Surface sediments were sampled along 2 transects, across the Iceland and Irminger basins and in the Labrador Sea. Clay mineral assemblages (deduced from X-ray analyses of the carbonate-free <2 mu m ... [more ▼]

Surface sediments were sampled along 2 transects, across the Iceland and Irminger basins and in the Labrador Sea. Clay mineral assemblages (deduced from X-ray analyses of the carbonate-free <2 mu m fraction) are largely dominated by smectites (about 60%) in the Iceland and Irminger basins. In the Labrador Sea, smectites are present along the Greenland Slope, but absent or rare in sediments from the Labrador Slope. They may, however, represent up to 50% of the clay fraction at depths between 2800 and 3400 m along both margins of the Labrador Sea, i.e., along the axis of the Western Boundary Undercurrent (WBUC). A detrital supply from the adjacent continents is unlikely. The WBUC is thought to be responsible for erosion and transport of fine particles from the smectite-rich Irminger and Iceland Basins, then for their redeposition in the Labrador Sea. These results suggest that clay minerals can be used as paleocurrent indicators in the Northwest Atlantic. [less ▲]

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See detailAssessment of the cell-mediated immunity in cattle infection after bovine herpesvirus 4 infection, using an in vitro antigen-specific interferon-gamma assay.
Godfroid, J.; Czaplicki, G.; Kerkhofs, P. et al

in Veterinary Microbiology (1996), 53(1-2), 133-41

The cell-mediated immunity (CMI) following bovine herpesvirus 4 (BHV4) infection has been poorly investigated in cattle. The in vivo response measured by a delayed type of hypersensitivity (DTH) assay has ... [more ▼]

The cell-mediated immunity (CMI) following bovine herpesvirus 4 (BHV4) infection has been poorly investigated in cattle. The in vivo response measured by a delayed type of hypersensitivity (DTH) assay has been reported to be positive in only few animals showing serological evidences of BHV4 infection. We have investigated the CMI following BHV4 infection by an in vitro antigen-specific interferon gamma (IFN-gamma) release assay, as an indicator of an actively acquired immunity to BHV4. Our preliminary results using a partially purified antigen suggest that there was a measurable CMI in 75 out of 168 animals (44.4%) originating from a farm with a clinical history and serological evidences (76.3% seropositivity) of BHV4 infection. If the results of serological tests and BHV4 IFN-gamma test are interpreted in parallel, 81.5% of the animals are classified positive, demonstrating the complementarity of these tests. The specificity of the BHV4 IFN-gamma test was supported by the absence of a measurable CMI in 41 animals originating from a farm with no clinical history or serological evidence of BHV4 infection. In an allied study, we developed a bovine herpesvirus 1 (BHV1) IFN-gamma test. This allowed us to measure the antigen specific IFN-gamma release after stimulation with a mixture of BHV1 and BHV4 antigens. Animals that were classified negative by the BHV4 IFN-gamma test and by the BHV1 IFN-gamma test, were classified negative after stimulation with a mixture of both antigens. Animals that were classified positive by the BHV4 IFN-gamma test or the BHV1 IFN-gamma test, were classified positive after stimulation with a mixture of both antigens. Taken together these results suggest that the in vitro assessment of the CMI after BHV4 infection should be further investigated as a specific and valuable alternative to the DTH assay. [less ▲]

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See detailLa gale psoroptique bovine. Une maladie éradicable ?
Mignon, Bernard ULg; Lonneux, J. F.; Losson, Bertrand ULg

in Sillon Belge (1996), 20.12.1996

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See detailThe short duration and anorogenic character of anorthosite magmatism: U-Pb dating of the Rogaland complex, Norway
Schärer, Urs; Wilmart, Edith; Duchesne, Jean-Clair ULg

in Earth & Planetary Science Letters (1996), 139

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See detailMaladie de Hodgkin et facteurs de croissance
Fillet, Georges ULg

in Tempo Médical (1996), 166

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See detailIpriflavone in prevention and treatment of postmenopausal and senile osteoporosis
Reginster, Jean-Yves ULg

in Osteoporosis News (1996), 4

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See detailA field observation on the influence of aggressive behaviour on mating success in the European grayling
Poncin, Pascal ULg

in Journal of Fish Biology (1996), 48(4), 802-804

The biggest male grayling present on a spawning area was strongly territorial and developed more aggressive behaviours than smaller males. However, its spawning frequency was similar to that of smaller ... [more ▼]

The biggest male grayling present on a spawning area was strongly territorial and developed more aggressive behaviours than smaller males. However, its spawning frequency was similar to that of smaller males. (C) 1996 The Fisheries Society of the British Isles [less ▲]

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See detailLe clonage par transfert de noyau dans l'espece bovine: resultats et perspectives.
Ectors, Fabien ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1996), 151(12), 493-9

A all in vitro cloning technique was developed in which the reconstituted embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer ... [more ▼]

A all in vitro cloning technique was developed in which the reconstituted embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer (recloning). Such method permitted to produce 14.5% of morulae and 14.9% of blastocysts after the first and second cycles of nuclear transfer, respectively. The rates of birth obtained after transfer of such embryos were 21.4% et 20.8% for first and second cycles respectively, corresponding to 6 et 5 calves for 28 et 24 transferred embryos. Unfortunately, gestation pathologies and an increase of birth weights were observed. It seems that the in vitro presence of gametes and/or embryos may be responsible of an alteration in the control of gene expression. [less ▲]

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See detailHyperfine structure of Sc I by Infrared Fourier Transform Spectroscopy
Aboussaïd, A.; Carleer, M.; Hurtmans, D. et al

in Physica Scripta (1996), 53

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See detailRecent advances in prostate cancer metastasis
Waltregny, David ULg; Castronovo, Vincenzo ULg

in Tumori (1996), 82(3, May-Jun), 193-204

Prostate cancer in men has now surpassed lung cancer as the most frequent non-cutaneous cancer. From a biological perspective, prostate carcinoma is unique among human malignancies in the wide discrepancy ... [more ▼]

Prostate cancer in men has now surpassed lung cancer as the most frequent non-cutaneous cancer. From a biological perspective, prostate carcinoma is unique among human malignancies in the wide discrepancy that exists between the prevalence of 'latent' cancer, recognizable only histologically, and that of the clinical disease. Histologically detected localized prostate cancers are heterogeneous, with only a small subset having undergone all of the malignant changes required to produce clinically aggressive tumors. Most of these 'latent' carcinoma never become fully malignant and do not threaten the life or well-being of the host. At present, it is not possible to predict which localized cancers will progress to clinically overt disease. Likewise, many patients have underevaluated and unpredictable extent of their prostate carcinoma, thus resulting in inadequate therapeutic strategies. It is clear that we need to identify molecular and/or cellular markers that are able to define the invasive and metastatic potential of prostate cancer on an individual patient basis. Acquisition of metastatic ability is a definitive criterion by which substage localized prostate cancers. Under the light of recent studies designed to identify some of the features associated with the metastatic phenotype of prostate cancer, the authors review recent advances aimed at gaining insight into those factors that may be involved in prostate cancer metastasis. [less ▲]

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See detailHaemodynamic dysfunctions involved in experimental bovine pneumonic pasteurellosis
Desmecht, Daniel ULg; Amory, Hélène ULg; Linden, Annick ULg et al

in Journal of Experimental Animal Science (1996), 37

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See detailDesign and modeling of new platelet-activating factor antagonists.2. Synthesis and biological activity of 1,4-bis-(3',4',5'-trimethoxybenzoyl)-2-alkyl and 2-alkoxymethylpiperazines
Tavet, Fabrice; Lamouri, Aazdine; Heymans, Françoise et al

in Journal of Lipid Mediators and Cell Signalling (1996), 15

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See detailLe campus universitaire comme espace public : des représentations aux pratiques
Frankignoulle, Pierre ULg; Bodson, Edith

in Etudes de Communication (1996), 18

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See detailTheory of the thermal conductivity of metallic localized spin compounds in a magnetic field
Rassili, Ahmed ULg; Ausloos, Marcel ULg

in Journal of Magnetism & Magnetic Materials (1996), 163(1-2), 153-163

We calculated the influence of a de magnetic field on the thermal conductivity of localized spin metallic systems as a function of temperature. A variational method was used. The influence of the joint ... [more ▼]

We calculated the influence of a de magnetic field on the thermal conductivity of localized spin metallic systems as a function of temperature. A variational method was used. The influence of the joint impurity and phonon scattering processes together with the localized spin influence is shown. Remarkable features are found at low temperature and near the critical transition. An increase of conductivity with field near T-C is discussed. It is also argued that a coherent effect due to the field is the cause of the thermal conductivity enhancement at low temperature. The magneto-thermal conductivity is shown at different temperatures. [less ▲]

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See detailThe current situation of wild mammals in Belgium: an outline
Libois, Roland ULg

in Hystrix: the Italian Journal of Mammalogy (1996), 8(1-2), 35-41

The distrbution of the wild mammals of Belgium has been intensively stutied during the years '78-81'. It was the first time that such a work was undertaken in Belgium and could lead to a better ... [more ▼]

The distrbution of the wild mammals of Belgium has been intensively stutied during the years '78-81'. It was the first time that such a work was undertaken in Belgium and could lead to a better understanding of the current status of the different species. Conservation measures were olso proposed to the political authorities who thereafter edicted a legal protection of the most vulnerable species. Unfortunately, habitat protection is rather unachieved and the situation of the most endangered species is still getting worse. [less ▲]

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See detailBiodegradable and macroporous polylactide implants for cell transplantation : 1. Preparation of macroporous polylactide supports by solid-liquid phase separation
Schugens, Ch; Maquet, Véronique; Grandfils, Christian ULg et al

in Polymer (1996), 37(6), 1027-1038

Freeze-drying of polylactide solutions in 1,4-dioxane has been studied as a way to produce microcellular foams. The thermally induced phase separation has been studied in relation to several processing ... [more ▼]

Freeze-drying of polylactide solutions in 1,4-dioxane has been studied as a way to produce microcellular foams. The thermally induced phase separation has been studied in relation to several processing and formulation parameters. The effects of polymer concentration, chain stereoregularity, polymer molecular weight and cooling rate have been investigated in connection with the porous morphology and the physico-mechanical characteristics of the final foams. As a rule, bundles of channels are formed with a diameter of ~100 μ.m. They have a preferential orientation that fits the cooling direction. A porous substructure (~10 μm) is observed in the internal walls of the tubular macropores. Variations in this general porous morphology-and particularly in the porosity, density, solvent residue, mechanical resistance and degree of regularity in the spatial organization of pores-have been observed when polymer concentration in 1,4-dioxane and polylactide stereoregularity are changed. As expected, cooling rate has a strong effect on the foam morphology, which is essentially controlled by the solvent crystallization. Pores are nothing but the fingerprints of 1,4-dioxane crystallites. [less ▲]

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See detailComparative evaluation of impulse oscillometry and a monofrequency forced oscillation technique in clinically healthy calves undergoing bronchochallenges
Reinhold, Petra; MacLeod, D.; Lekeux, Pierre ULg

in Research in Veterinary Science (1996), 61

Multifrequency impulse oscillometry (IOS) was compared with a monofrequency forced oscillation technique (MFO) in calves undergoing experimentally induced bronchoconstriction and subsequent ... [more ▼]

Multifrequency impulse oscillometry (IOS) was compared with a monofrequency forced oscillation technique (MFO) in calves undergoing experimentally induced bronchoconstriction and subsequent bronchodilatation. The dynamic lung compliance (Cdyn) was also measured by conventional methods. For each test, the baseline mean and the responses to saline, a bronchoconstrictive agent (carbachol) and a bronchodilator (fenoterolhydrobromide) were calculated. Using the IOS, the information was markedly frequency-dependent. The resistance (R) and the magnitude of respiratory impedance (Z) were only sensitive at 5 Hz, leading to negative frequency dependence of these parameters as an indicator of peripheral airway obstruction. A high sensitivity for reactance (X) and phase angle phi values was observed between 5 and 20 Hz. For MFO (10 Hz), the parameters Ros (which includes resistive and capacitive components of the respiratory system), phase shift (psi), and the oscillatory derived compliance of the respiratory system (Crs) were of the greatest clinical potential. Crs showed a significant coefficient of linear correlation (r = 0.88, P < 0.001) with Cdyn. At the 10 Hz test frequency similar results were observed with MFO and IOS, suggesting that for healthy calves the measurement effect of an impulse is not significant. With respect to peripheral airway calibre, a test frequency less than 10 Hz appeared to be most sensitive and least variable. [less ▲]

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See detailIncidence et coûts sociaux directs de la fracture du fémur
Gillet, Pierre ULg; Reginster-Haneuse, G; Reginster, Jean-Yves ULg

in Les Nouvelles de Rhumatologie (1996), 1

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See detailMicroscopic observation of the retinal photoreceptor layer of the common barbel (Teleostei: Cyprinidae)
Compère, Philippe ULg; Poncin, Pascal ULg

in Belgian Journal Of Zoology (1996), 126(1), 49-56

Light and electron microscopic observations show that cones-belonging to four types are present in the retina of the common barbel Barbus barbus (L.): short single cones, long single cones, twin cones ... [more ▼]

Light and electron microscopic observations show that cones-belonging to four types are present in the retina of the common barbel Barbus barbus (L.): short single cones, long single cones, twin cones, and unequal double cones. They do not exhibit any particular arrangement. Estimates of cone density suggest that the common barbel has multichromatic vision but of low acuity and that no difference exists between the lower and the upper parts of the retina. Both cone density (approximately 3000 units/mm(2)) and the proportion of double cones to single cones (approximately 1:3) are low. The view that the barbel has an inferior colour vision is in good agreement with the fact that this species is active mainly at twilight, but with diurnal activity during spawning. [less ▲]

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See detailThe efficacy of a phyto-aromatic ear gel against auricular mange in rabbits and carnivores
Mignon, Bernard ULg; Losson, Bertrand ULg

in Veterinary Record : Journal of the British Veterinary Association (1996), 138

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See detailLaparoscopic myomectomy today. Fibroids: management and treatment: the state of the art.
Donnez, Jacques; Mathieu, Pierre Emmanuel; Bassil, Salim et al

in Human Reproduction (1996), 11(9), 1837-40

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See detailStrigula kaitokensis sp. nov. from New Zealand
Sérusiaux, Emmanuël ULg; Polly, Barbara

in Mycotaxon (1996), 59

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See detailInsectes ravageurs: Protection des grains stockés
Mignon, Jacques ULg; Haubruge, Eric ULg; Gaspar, Charles

in Agricontact (1996), 287

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See detailThe Potent Angioinhibin Agm-1470 Stimulates Normal but Not Human Tumoral Lymphocytes
Antoine, Nadine ULg; Daukandt, M.; Locigno, R. et al

in Tumori (1996), 82(1, Jan-Feb), 27-30

BACKGROUND: AGM-1470 is a newly synthesized molecule developed as an analog of the potent anti-angiogenic fumagillin. Its efficacy in restraining tumor growth in vivo and the absence of major side effects ... [more ▼]

BACKGROUND: AGM-1470 is a newly synthesized molecule developed as an analog of the potent anti-angiogenic fumagillin. Its efficacy in restraining tumor growth in vivo and the absence of major side effects have already led to phase I clinical trials in patients with solid cancers. However, neither the exact mechanisms of action of AGM-1470 nor its effects on the host of normal cells have been extensively studied. Recently, we showed that AGM-1470 enhanced the proliferation of B lymphocytes in the presence of T cells. Since AGM-1470 could potentially be used in patients with lymphoma, it was urgent to test the effect of the molecule on the proliferation of tumor lymphocytes. METHODS: The possible effect of AGM-1470 on the proliferation of normal or tumor lymphocytes was evaluated by thymidine-incorporated assays. Normal T and B lymphocytes were purified from human tonsils. The tumor lymphocytes used in the study were Molt 3, Molt 4 and Jurkatt cell lines for the T lineage and Daudi and Radji cell lines for the B lineage. RESULTS: As shown previously, AGM-1470 stimulates the proliferation of normal B lymphocytes through an action on normal T cells. THe angioinhibin was ineffective ont eh proliferation of both T and B transformed cells. Moreover, in the presence of the drug, tumor T cells co-cultured with normal B lymphocytes did not induce any increase in B cell proliferation, as previously observed with normal T lymphocytes. Inversely, tumor B cells co-cultured with normal T lymphocytes were insensitive to the drug. CONCLUSIONS: Our results demonstrate that AGM-1470 is ineffective on lymphoid tumor cell proliferation and could potentially be safely administered to lymphoma patients. [less ▲]

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See detailAn improved preparation method of benzyl and thenyl triphenylphosphonium salt
Zhang, Jian-Xin; Dubois, Philippe ULg; Jérôme, Robert ULg

in Synthetic Communications (1996), 26(16), 3091-3095

New benzyl and thenyl phosphonium salts have been prepared by an improved method in solution from the parent alcohols and triphenylphosphine hydrobromide. Benzyl-type alcohols containing a tertiary amine ... [more ▼]

New benzyl and thenyl phosphonium salts have been prepared by an improved method in solution from the parent alcohols and triphenylphosphine hydrobromide. Benzyl-type alcohols containing a tertiary amine can also be converted within high yields to phosphonium salts by removing the formed water by azeotropic distillation. Solvent (methylene chloride, chloroform and acetonitrile) and temperature have been chosen in close relation to the alcohol reactivity. Purification is straightforward and yields are relatively high. [less ▲]

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See detailFreud, l'individu et le groupe : Hier et aujourd'hui
Carels, N.; Gauthier, Jean-Marie ULg

in Revue Belge de Psychanalyse (1996), 29

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See detailLa réforme du premier degré en Communauté française de Belgique veut relever le défi d'une pédagogie de la réussite
Beckers, Jacqueline ULg

in Recherche en Education. Théorie & Pratique (1996), 5-6

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