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See detailFructose utilization during exercise in men: rapid conversion of ingested fructose to circulating glucose.
Jandrain, Bernard ULg; Pallikarakis, N.; Normand, S. et al

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1993), 74(5), 2146-54

The aim of the present study was to compare the metabolic fate of repeated doses of fructose or glucose ingested every 30 min during long-duration moderate-intensity exercise in men. Healthy volunteers ... [more ▼]

The aim of the present study was to compare the metabolic fate of repeated doses of fructose or glucose ingested every 30 min during long-duration moderate-intensity exercise in men. Healthy volunteers exercised for 3 h on a treadmill at 45% of their maximal oxygen consumption rate. "Naturally labeled" [13C]glucose or [13C]fructose was given orally at 25-g doses every 30 min (total feeding: 150 g; n = 6 in each group). Substrate utilization was evaluated by indirect calorimetry, and exogenous sugar oxidation was measured by isotope ratio mass spectrometry on expired CO2. Results were corrected for baseline drift in 13C/12C ratio in expired air due to exercise alone. Fructose conversion to plasma glucose was measured combining gas chromatography and isotope ratio mass spectrometry. Most of the ingested glucose was oxidized: 81 +/- 4 vs. 57 +/- 2 g/3 h for fructose (2P < 0.005). Exogenous glucose covered 20.8 +/- 1.4% of the total energy need (+/- 6.7 MJ) compared with 14.0 +/- 0.6% for fructose (2P < 0.005). The contribution of total carbohydrates was significantly higher and that of lipids significantly lower with glucose than with fructose. The blood glucose response was similar in both protocols. From 90 to 180 min, 55-60% of circulating glucose was derived from ingested fructose. In conclusion, when ingested repeatedly during moderate-intensity prolonged exercise, fructose is metabolically less available than glucose, despite a high rate of conversion to circulating glucose. [less ▲]

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See detailLes chimpanzés : un modèle animal de la relation clientélaire
Servais, Véronique ULg

in Terrain (1993), 21(octobre), 67-80

The paper is about the dominance and coalition relationship among male chimpanzees. It focuses on the dependance relationship between the members of the coalition and distinguishes stable and unstable ... [more ▼]

The paper is about the dominance and coalition relationship among male chimpanzees. It focuses on the dependance relationship between the members of the coalition and distinguishes stable and unstable coalitions. A coalition is unstable if the support of the dominated individual is conditional and stable if it is not (i.e. among two brothers). In an unstable coalition the dominated indivuual can afford some priviledge, the dominant is very dependent on the subordinate and the relationship with the dominant is tense. Analogies with human power relationships are suggested. [less ▲]

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See detailResistance a la secheresse et reponses a l'acide abscissique: analyse d'une approche synthetique.
El-Jaafari, S.; Paul, Roger ULg; Lepoivre, Philippe ULg et al

in Cahiers Agricultures (1993), 2(4),

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See detailDesign and modeling of new platelet-activating-factor antagonists.1. Synthesis and biological activity of 1,4-bis(3',4',5'-trimethoxybenzoyl)-2-[[(substituted carbonyl and carbamoyl)oxy]methyl]piperazines
Lamouri, Aazdine; Heymans, Françoise; Tavet, Fabrice et al

in Journal of Medicinal Chemistry (1993), 36(8), 990-1000

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See detailEndogenous substrate oxidation during exercise and variations in breath 13CO2/12CO2.
Gautier, J. F.; Pirnay, Freddy ULg; Jandrain, Bernard ULg et al

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1993), 74(1), 133-8

This study attempted to induce a major shift in the utilization of endogenous substrates during exercise in men by the use of a potent inhibitor of adipose tissue lipolysis, Acipimox, and to see to what ... [more ▼]

This study attempted to induce a major shift in the utilization of endogenous substrates during exercise in men by the use of a potent inhibitor of adipose tissue lipolysis, Acipimox, and to see to what extent this affects the 13C/12C ratio in expired air CO2. Six healthy volunteers exercised for 3 h on a treadmill at approximately 45% of their maximum O2 uptake, 75 min after having ingested either a placebo or 250 mg Acipimox. The rise in plasma free fatty acids and glycerol was almost totally prevented by Acipimox, and no significant rise in the utilization of lipids, evaluated by indirect calorimetry, was observed. Total carbohydrate oxidation averaged 128 +/- 17 (placebo) and 182 +/- 21 g/3 h (Acipimox). Conversely, total lipid oxidation was 84 +/- 5 (placebo) and 57 +/- 6 g/3 h (Acipimox; P < 0.01). Under placebo, changes in expired air CO2 delta 13C were minimal, with only a 0.49/1000 significant rise at 30 min. In contrast, under Acipimox, the rise in expired air CO2 delta 13C averaged 1/1000 and was significant throughout the 3-h exercise bout; in these conditions calculation of a "pseudooxidation" of an exogenous sugar naturally or artificially enriched in 13C, but not ingested, would have given an erroneous value of 19.8 +/- 2.6 g/3 h. Thus under conditions of extreme changes in endogenous substrate utilization, an appropriate control experiment is mandatory when studying exogenous substrate oxidation by 13C-labeled substrates and isotope-ratio mass spectrometry measurements on expired air CO2. [less ▲]

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See detailMeasurement of the 2s2p2(4P)3s 3P2 lifetime in N II by beam-foil-laser spectroscopy
Bastin, Thierry ULg; Baudinet-Robinet, Y.; Garnir, Henri-Pierre ULg et al

in Journal Physical II (1993), 3

An accurate value for the radiative lifetime of the 2s2p2(4P)3s3P2 level in N II has been obtained using the beam-foil-laser spectroscopy method. The result (T = 0.456 ± 0.020 ns ) is shorter than the ... [more ▼]

An accurate value for the radiative lifetime of the 2s2p2(4P)3s3P2 level in N II has been obtained using the beam-foil-laser spectroscopy method. The result (T = 0.456 ± 0.020 ns ) is shorter than the beam-foil lifetime values reported previously for the 3s' 3P term. No theoretical value for the lifetime of this term is available at the present time. [less ▲]

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See detailIntérêt du monitoring ambulatoire de la PA de 24 h en pratique quotidienne
Saint-Remy, Annie ULg; Rorive, Georges ULg

in Profil (1993)

L'avènement et les apports incontestablement positifs du monitoringe PA en ambulatoire ne remettent pas en question toutes les connaissances acquises depuis des décennies sur base de la PA mesurée ... [more ▼]

L'avènement et les apports incontestablement positifs du monitoringe PA en ambulatoire ne remettent pas en question toutes les connaissances acquises depuis des décennies sur base de la PA mesurée traditionnellement. On doit encore attendre des directives en matière de diagnostic et de thérapeutique. Une appréciation plus précise du statut tensionnel du patient, du type d'hypertension ainsi que du contrôle de PA pendant le nycthémère par les médications, constituent des avantages potentiels qui devraient sensibiliser les praticiens son utilisation. [less ▲]

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See detailUne logique de l'anorexie mentale
Servais, Véronique ULg

in Revue Internationale de Systémique (1993), 7(4), 385-418

The paper presents a batesonian approach of anorexia nervosa. The illness is viewed as a positive feedback loop. The first restrictions appear as a solution to diverse problems of adolescence. Then the ... [more ▼]

The paper presents a batesonian approach of anorexia nervosa. The illness is viewed as a positive feedback loop. The first restrictions appear as a solution to diverse problems of adolescence. Then the restrictions become a deutero-learning : the girl finds pleasure and security in restriction behaviours. She si permanently looking for challenging contexts where she can proof her self control. Because the control is a deutero-learning the behavior cannot be diminished through punishment. Only the restoration of relationships with the whole personnality and the environment can give the girl the therapeutic experience of becoming to as system that she cannot control. [less ▲]

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See detailEffects of a 1-year treatment with a low-dose combined oral contraceptive containing ethinyl estradiol and cyproterone acetate on glucose and insulin metabolism.
Scheen, André ULg; Jandrain, Bernard ULg; Humblet, Dominique ULg et al

in Fertility and Sterility (1993), 59(4), 797-802

OBJECTIVE: To study the effects of the slightly estrogen-dominant monophasic low-dose oral contraceptive (OC) Diane-35 (Schering AG, Berlin, Germany) (35 micrograms ethinyl estradiol [EE2] + 2 mg ... [more ▼]

OBJECTIVE: To study the effects of the slightly estrogen-dominant monophasic low-dose oral contraceptive (OC) Diane-35 (Schering AG, Berlin, Germany) (35 micrograms ethinyl estradiol [EE2] + 2 mg cyproterone acetate, a 17 alpha-hydroxyprogesterone derivative [17-OHP]) on glucose and insulin metabolism. DESIGN: Seven healthy young women were investigated by using the euglycemic hyperinsulinemic glucose clamp technique (insulin delivery rate = 100 mU/kg per hour for 120 minutes). This test was performed, after an overnight fast, during the last 7 days of a spontaneous cycle and within the last 5 days of pill intake during the sixth and twelfth cycle of a continuous treatment with Diane-35 in each subject. RESULTS: The three indexes measuring the insulin-induced glucose disposal during the clamp (glucose infusion rate, glucose metabolic clearance rate, and glucose infusion rate divided by plasma insulin plateau levels) were not significantly affected by Diane-35. In contrast, the metabolic clearance rate of the exogenous insulin infused during the clamp tended to be slightly increased with Diane-35 (significant after 6 but not after 12 cycles). CONCLUSION: These results suggest that a 1-year treatment with the OC Diane-35, which contains EE2 + a 17-OHP rather than a 19-nortestosterone derivative as the progestogen compound, does not significantly alter peripheral (presumably muscular) insulin sensitivity but slightly increases insulin (presumably hepatic) clearance. [less ▲]

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See detailTHE CERTIFIED TOTAL GLUCOSINOLATE CONTENT IN 3 RAPESEEDS (CRM-190, CRM-366 AND CRM-367)
Wathelet, Jean-Paul ULg; WAGSTAFFE, P. J.; BOENKE, A. et al

in Fresenius' Journal of Analytical Chemistry (1993), 347(10-11), 396-399

The preparation of certified rapeseed reference materials and the steps taken to establish the certified values for total glucosinolate contents are described. Details are given of the studies to ... [more ▼]

The preparation of certified rapeseed reference materials and the steps taken to establish the certified values for total glucosinolate contents are described. Details are given of the studies to demonstrate the homogeneity and stability of the material. The results of the certification exercise for total glucosinolate content, which involved European laboratories who applied a variety of methods (high-pressure liquid chromatography, gas liquid chromatography, determination of enzymatically released glucose and sulphate), are presented and discussed. The certified values for the glucosinolate content (mumol/g of non-defatted whole seeds) and the 95% confidence level are the following: CRM 366 (12.1 +/- 0.8 mumol/g), CRM 190 (25.5 +/- 0.9 mumol/g) and CRM 367 (102.4 +/- 3 mumol/g) (CRM = certified reference material). Indicative values (not certified) for individual glucosinolates are also given. Certified sulphur values (mg/g of non defatted whole seeds) have been determined by other laboratories: CRM 366 (3.41 +/- 0.12 mg/g), CRM 190 (4.93 +/- 0.15 mg/g) and CRM 367 (10.5 +/- 0.40 mg/g). [less ▲]

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See detailSequence of the triosephosphate isomerase-encoding gene isolated from the thermophile Bacillus stearothermophilus
Rentier-Delrue, Françoise ULg; Moyens, Sylvianne; Lion, Michelle ULg et al

in Gene (1993), 134(1), 137-8

By analysis of genomic clones, we have determined the complete nucleotide sequence of the gene encoding triosephosphate isomerase (TIM; EC 5.3.1.1) in the thermophilic bacterium, Bacillus ... [more ▼]

By analysis of genomic clones, we have determined the complete nucleotide sequence of the gene encoding triosephosphate isomerase (TIM; EC 5.3.1.1) in the thermophilic bacterium, Bacillus stearothermophilus. The gene encodes a 253-amino-acid TIM which is 39% identical to that of the mesophile, Escherichia coli. [less ▲]

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See detailEffect of a Booster Vaccination against Influenza and Equine Herpes Virus on Cardio-Respiratory Adjustments to Strenuous Exercise and Training in Thoroughbred Horses
Art, Tatiana ULg; Lekeux, Pierre ULg

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (1993), 40(7), 481-491

This study was conducted in order to assess whether exercise- and training-induced cardio-respiratory adjustments are modified during the 10-day period which follows a booster vaccination with an oily ... [more ▼]

This study was conducted in order to assess whether exercise- and training-induced cardio-respiratory adjustments are modified during the 10-day period which follows a booster vaccination with an oily adjuvanted inactivated vaccine against influenza and equine herpesvirus-1 (Equiffa). Nine healthy vaccinated thoroughbred horses were used. Six were revaccinated and three were kept as control. All the horses completed a standardised exercise test (SET) that was repeated 4 times, i.e. 10 (SET1) and 2 (SET2) days before revaccination, and 2 (SET3) and 10 (SET4) days after revaccination. During the whole experimental period the horses were trained 6 days per week according to an interval training schedule. Respiratory airflow, tidal volume, respiratory rate and expired minute volume (VE) were measured using a face mask and 2 ultra-sonic pneumotachographs. The oxygen uptake (VO2) and carbon dioxide production (VCO2) were obtained on a breath-by-breath basis, using a mass spectrometer. Heart rate (HR) was continuously measured with a polar horse tester. Venous blood was sampled before and after the test and analysed for biochemical determinations. Blood was also sampled before and 21 days after the booster vaccination for circulating antibody titration. The peak VO2, VCO2, ventilatory equivalent (VE/VO2) and oxygen pulse (VO2/HR) were significantly improved by the 3-week training period. The other cardio-respiratory parameters as well as most of the blood parameters remained unchanged throughout the 4 SETs. The revaccination did not impair any of the parameters measured before, during, or after the SETs. All revaccinated horses showed a rise in antibodies against influenza virus type A1 and A2 and EVH-1 compared to the control horses. It was concluded that, in our horses, revaccination with an oily adjuvanted inactivated vaccine against influenza and EVH-1 did not impair their cardiorespiratory and metabolic adjustments to strenuous exercise and intense training, and that the seroconversion due to revaccination was unaffected by the intense daily exercise experienced by the animals in the post-vaccination period [less ▲]

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See detailA VARIABLE MECHANISM FOR THE NUCLEOPHILIC VINYLIC SUBSTITUTIONS IN A SERIES OF GEM-DIHALOGENATED ALKENES BY A BIDENTATE SULFUR NUCLEOPHILE - AN EXPERIMENTAL AND AM1 THEORETICAL-STUDY
Gimbert, Yves; Moradpour, Alec; Dive, Georges ULg et al

in Journal of Organic Chemistry (1993), 58(17), 4685-4690

The nucleophilic substitutions of a series of gem-dihalogenated alkenes 3,5,7,8, and 9 (RS)2C=CX2 (X = Cl, F) with 1,2-benzenedithiolate b have been studied. Depending on the structures of the R groups ... [more ▼]

The nucleophilic substitutions of a series of gem-dihalogenated alkenes 3,5,7,8, and 9 (RS)2C=CX2 (X = Cl, F) with 1,2-benzenedithiolate b have been studied. Depending on the structures of the R groups (alkyl, saturated and unsaturated cycloalkyls, aromatic ring), the course of the reactions and the structures of the yielded products are modified. In the frame of the addition-elimination-type mechanism for these nucleophilic substitutions, the energy contents of the anionic intermediates, resulting from the additions of the nucleophile b to the unsaturated centers, is calculated at the AM1 method level. For the compounds 5, 7, 8, and 9, the calculated energies nicely corroborate the experimental results. For 3, anionic intermediates are no longer found by calculation, and a synchronous single-step substitution is strongly suggested. [less ▲]

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See detailLa ferritine érythrocytaire
Guillemin, Ch; Revenant, M. C.; Vernet, V. et al

in Annales de Biologie Clinique (1993), 51

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See detailTEM investigation of transition phases precipitation in ZA alloys after isothermal aging at 250°C and subsequent creep at high temperature
Lecomte-Beckers, Jacqueline ULg; Terziev, L.; Wegria, J.

in Materials Science Forum (Intergranular and Interphase Boundaries in Materials) (1993), 126-128

Transition phases occurring during isothermal aging at 250°C af ternary Zri-A1-Cu alloys are modlifîed after creep at high temperature. fle pressure applkd during creep leads to a high dertsity of clef ... [more ▼]

Transition phases occurring during isothermal aging at 250°C af ternary Zri-A1-Cu alloys are modlifîed after creep at high temperature. fle pressure applkd during creep leads to a high dertsity of clef ects which modifies the ndcrostructure. 11e trnsitiôn phases are studied by me ans of transmission electron microscopy and diffraction technique. Œ’r and phases pile up on dislocations. 11e reaction «s + £ 4 T +r 1$ accelerated and the transition T’ -. e’ is proxnoted by the defects. [less ▲]

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See detailHomologous recombinant growth hormone and calcium metabolism in the tilapia oreochromis mossambicus, adapted to freshwater
Flik, G.; Atsma, W.; Fenwick, J. C. et al

in Journal of Experimental Biology (1993)

Homologous recombinant tilapia growth hormoe was tested for its effect on calcium metabolism in freshwater tilapia Oreochromis mossambicus. A comparison of the role of GH and prolactin in calcium ... [more ▼]

Homologous recombinant tilapia growth hormoe was tested for its effect on calcium metabolism in freshwater tilapia Oreochromis mossambicus. A comparison of the role of GH and prolactin in calcium regulation of the tilapia led to the conclusion that GH has specific calciopropic effects on freshwater Tilapia that differ from those of prolactin. [less ▲]

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See detailStructure of the 16 S ribosomal RNA of the thermophilic cyanobacterium Chlorogloeopsis HTF (‘Mastigocladus laminosus HTF’) strain PCC75 18, and phylogenetic analysis
Wilmotte, Annick ULg; Van Der Auwera, Gert; De Wachter, Rupert

in FEBS Letters (1993), 317

The thermophilic cyanobacterial strain, PCC7518, originally identified as ‘Mu~tigocludus hminosus HTF’ does not show branchings or heterocysts. The absence of branchings supports the later assignment to ... [more ▼]

The thermophilic cyanobacterial strain, PCC7518, originally identified as ‘Mu~tigocludus hminosus HTF’ does not show branchings or heterocysts. The absence of branchings supports the later assignment to the genus Chlorogloeopsu. The absence of heterocysts may be the result of a mutation because heterocysts were observed in the original isolate. Alternatively, contamination may have happened. To solve this problem, the 16 S rRNA sequence was determined and used to infer a secondary structure model and build distance trees. The trees showed that strain PCC7518 belongs to the cluster of heterocystous species and has most probably lost the abihty to produce heterocysts by mutation. It is only distantly related to Chlorogloeopsis fritschii PCC67 18. [less ▲]

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See detailA sulfonylthiourea (BM 20) related to torasemide: a new loop diuretic with relative potassium-sparing properties
Masereel, B.; Schynts, M.; Krzesinski, Jean-Marie ULg et al

in Journal of Pharmacy & Pharmacology (1993), 45

A series of sulphonylthioureas related to torasemide, a high ceiling loop diuretic, were synthesized and found to inhibit the Na+ 2Cl- K+ co-transporter of the thick ascending limb of the loop of Henlé ... [more ▼]

A series of sulphonylthioureas related to torasemide, a high ceiling loop diuretic, were synthesized and found to inhibit the Na+ 2Cl- K+ co-transporter of the thick ascending limb of the loop of Henlé. Their diuretic properties were studied (30 mg kg-1) after oral administration to rats. Lipophilic derivatives very active in-vitro, were found inactive orally and intraperitoneally in rats. The four most active compounds were examined for their dose-dependent diuresis. Three of them showed a potency, water and electrolyte excretion similar to torasemide. The fourth molecule, a sulphonylthiourea (BM 20), exhibited relative potassium-sparing properties and a minimal diuretic dose of 0.001 mg kg-1, 200 times lower than torasemide. [less ▲]

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See detailOccurrence of contrasting skarn formations in dolomites of the Traversella deposit (Ivrea, Italy)
Vander Auwera, Jacqueline ULg; Verkaeren, Jean

in Geologische Rundschau : Zeitschrift für Allgemeine Geologie (1993), 82

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See detailHEXAGONAL MARANGONI CONVECTION IN A RECTANGULAR BOX WITH SLIPPERY WALLS
Dauby, Pierre ULg; Lebon, Georgy ULg; COLINET, P. et al

in Quarterly Journal Of Mechanics And Applied Mathematics (1993), 46(Part 4), 683-707

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See detailAnalgésie postopératoire par analgésie péridurale autocontrôlée
Joris, Jean ULg

in Douleur et analgésie (1993), 4

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See detailcr de J. Cerny, Papyrus hiératiques de Deir el-Médineh, t. II
Winand, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1993), 68

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See detailHemodynamic changes during laparoscopic cholecystectomy.
Joris, Jean ULg; Noirot, Didier P; Legrand, Marc ULg et al

in Anesthesia and Analgesia (1993), 76(5), 1067-71

Hemodynamics during laparoscopic cholecystectomy under general anesthesia (isoflurane in N2O/O2 (50%)) were investigated in 15 nonobese ASA Class I patients by using invasive hemodynamic monitoring ... [more ▼]

Hemodynamics during laparoscopic cholecystectomy under general anesthesia (isoflurane in N2O/O2 (50%)) were investigated in 15 nonobese ASA Class I patients by using invasive hemodynamic monitoring including a flow-directed pulmonary artery catheter. During surgery, intraabdominal pressure was maintained automatically at 14 mm Hg by a CO2 insufflator, and minute ventilation was controlled and adjusted to avoid hypercapnia. Hemodynamics were measured before anesthesia, after the induction of anesthesia, after tilting into 10 degrees head-up position, 5 min, 15 min, and 30 min after peritoneal insufflation, and 30 min after exsufflation. Induction of anesthesia decreased significantly mean arterial pressure and cardiac index (CI). Tilting the patient to the head-up position reduced cardiac preload and caused further reduction of CI. Peritoneal insufflation resulted in a significant increase (+/- 35%) of mean arterial pressure, a significant reduction (+/- 20%) of CI, and a significant increase of systemic (+/- 65%) and pulmonary (+/- 90%) vascular resistances. The combined effect of anesthesia, head-up tilt, and peritoneal insufflation produced a 50% decrease in CI. Administration of increasing concentrations of isoflurane, via its vasodilatory activity, may have partially blunted these hemodynamic changes. These results demonstrate that laparoscopy for cholecystectomy in head-up position results in significant hemodynamic changes in healthy patients, particularly at the induction of pneumoperitoneum. [less ▲]

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See detailOnce daily administration of amikacin. Adaptation to neonatology for infants less than 3 days of postnatal age
Battisti, Oreste ULg

in Médecine et Maladies Infectieuses (1993), 23

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See detailNote sur les techniques de gravure des sceaux-cylindres en Asie antérieure
Tunca, Önhan ULg

in Technologie et analyse des gemmes anciennes (PACT 23) (1993)

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See detailHigh-Grade Pleomorphic T Cell Lymphoma with Restricted Involvement of Skin and Bone Marrow
Gautier, M. S.; Pierard, Gérald ULg; Andrien, Francine ULg et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (1993), 186(4), 287-9

Pleomorphic T cell lymphoma of the medium to large cell type expressing CD30 antigen is a most aggressive peripheral T cell lymphoma. Currently, there is no satisfactory treatment available for this ... [more ▼]

Pleomorphic T cell lymphoma of the medium to large cell type expressing CD30 antigen is a most aggressive peripheral T cell lymphoma. Currently, there is no satisfactory treatment available for this neoplasm. We report the case of a woman with prominent skin and bone marrow involvement without detectable lymph node localization. This unusual presentation of disease responded well to polychemotherapy combined with autologous bone marrow transplantation. [less ▲]

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See detailReaction Dynamics of the Dichlorocarbene Anion Using tandem Mass Spectrometry.
Leyh, Bernard ULg; Mélon, Pierre

in Organic Mass Spectrometry (1993), 28

The dissociation dynamics of CCl2- anions were studied under various internal energy conditions. This study involved the measurement of daughter-ion spectra and branching ratios and of the amount of ... [more ▼]

The dissociation dynamics of CCl2- anions were studied under various internal energy conditions. This study involved the measurement of daughter-ion spectra and branching ratios and of the amount of kinetic energy released (KER) on the fragments. The competition between C and Cl loss for CCl2- ions created by many of the following sequence of processes: CCl4->CCl2+->(G=Xe, Kr C6H6)->CCl2--> fragments (1); CCl4->(CCl2--+[Cl,Cl]+;CCl2-; CCl2- (Ne)-> Fragments (2); CCl4->(CCl2)2+ (C6H6)->CCl2--> fragments (3) was particularly investigated. For process (1), the amount of fragmentating CCl2- ions is 8-10 times larger with Kr than with Xe or C6H6. The KER for Cl loss is smaller than 0.20 eV with the three target gases used. For the loss of C, the KER is much larger (0.7 eV). This KER is, however, equal to 0.21 eV for the collisionally activated C loss in process (2). For this latter process, the C loss vs Cl loss branching ratio decreases with increasing internal energy. The KERs measured for process (3) are vary similar to those obtained for process (1). It is suggested that repulsive or slightly bound excited states which correlate directly to the Cl2-(X2Sigma+)+C asymptote and which are vibronically coupled to the ground state play an important role in these dissociation processes. [less ▲]

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See detailLa catalyse enzymatique en milieu organique : potentialités d'utilisation des lipases.
Blecker, Christophe ULg

in Bulletin des Recherches agronomiques de Gembloux (1993), 28(1), 51-85

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See detailUltrastructural distribution of DNA within the nucleolus of various animal cell lines or tissues revealed by terminal deoxynucleotidyl transferase.
Thiry, Marc ULg; Ploton, D.; Menager, M. et al

in Cell & Tissue Research (1993), 271(1), 33-45

We have used the highly sensitive in situ terminal deoxynucleotidyl transferase method, applied to ultrathin sections, to investigate the location of DNA within nucleoli of various animal cells. In all ... [more ▼]

We have used the highly sensitive in situ terminal deoxynucleotidyl transferase method, applied to ultrathin sections, to investigate the location of DNA within nucleoli of various animal cells. In all the nucleoli studied, intense labelling is revealed over the peri- and intranucleolar condensed chromatin. Gold particles are also consistently found over the fibrillar centres, especially at their periphery, namely in the border area between the fibrillar centres and the dense fibrillar component, whereas the dense fibrillar component itself seems to be free of label in nucleoli in which these two compartments can be distinguished. We conclude that, in transcriptionally active nucleoli of this type, DNA is a characteristic constituent of the fibrillar centres, distinguishing them functionally from the dense fibrillar component. Some nucleoli exhibit neither fibrillar centres nor a dense fibrillar component, but have a single, albeit heterogeneous accumulation of fibrillar material; gold particles are consistently seen over some parts of this fibrillar compartment. This suggests that certain parts of the fibrillar material are functionally similar to the fibrillar centres of those nucleoli that possess them. [less ▲]

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See detailComparison of three metrenperone dosage regimens inhibiting the 5-hydroxytryptamine-induced pulmonary dysfunction in cattle
Linden, Annick ULg; Desmecht, Daniel ULg; Amory, Hélène ULg et al

in Research in Veterinary Science (1993), 55

The effects of a 5-hydroxytryptamine (5-HT) challenge infusion on pulmonary function values were studied in healthy calves, pretreated with varying doses of metrenperone, a selective type 2 serotonergic ... [more ▼]

The effects of a 5-hydroxytryptamine (5-HT) challenge infusion on pulmonary function values were studied in healthy calves, pretreated with varying doses of metrenperone, a selective type 2 serotonergic (5-HT2) antagonist. In the first part of the experiment, the 5-HT challenge was performed 30 minutes after administration of metrenperone at a dose of 0.025 mg kg-1 (group 1, n = 8), 0.050 mg kg-1 (group 2, n = 8) and 0.100 mg kg-1 (group 3, n = 7). In the second part, the 5-HT challenge was performed 12 hours after administration of metrenperone at a dose of 0.050 mg kg-1 (group 4, n = 5) and 0.100 mg kg-1 (group 5, n = 5). None of the three doses of metrenperone influenced the 5-HT-induced ventilatory changes. For the challenge performed 30 minutes after blockade, all three doses inhibited the bronchoconstrictive process triggered by the 5-HT challenge. There was no dose-related inhibition. On the other hand, when the challenge was performed 12 hours after metrenperone, there was a dose-related inhibition with only the higher dose (0.100 mg kg-1) showing a significant efficacy in inhibiting 5-HT-induced bronchoconstriction. It is concluded that, if 5-HT is involved in the pathophysiological processes of respiratory diseases in cattle, a 5-HT2 blockade with metrenperone at a dose rate of 0.100 mg kg-1 and with a dosage interval of 12 hours should improve pulmonary function. [less ▲]

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See detailUtilisation d'un S.I.G. pour la gestion des ressources forestières : exemple d'application à un inventaire forestier régional
Lejeune, Philippe ULg; Lecomte, Hugues; Prevot, Hugues ULg

in Bulletin des Recherches Agronomiques de Gembloux (1993), 28(2-3), 275-286

The development of a Geographic Information System (G.I.S.) leads to new prospects in the field of broad-scale forest inventory, the main objective being to estimate areas and growing stock for the ... [more ▼]

The development of a Geographic Information System (G.I.S.) leads to new prospects in the field of broad-scale forest inventory, the main objective being to estimate areas and growing stock for the different stand types in a given region. The dot grid method typically used to estimate the areas in the case of systematic sampling, can be advantageously replaced by the creation within a G.I.S., of a stand map, that can be overlaid with data issued from the inventory. A methodology is proposed, to produce such a map using color infrared aerial photos at a scale of 1:25,000. Geographical data are processed using ILWIS software. The method has been tested on a 200 km² forest area. The error rate for interpretation of stand types is less than 6 % if one considers the confusions between species. The crossing of this stand map with the sample plots layer provides an estimation of the growing stock per stand type. [less ▲]

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See detailModeling of the chemical processes in a longwall face underground gasifier at great depth
COEME, Antoinette; Pirard, Jean-Paul ULg; MOSTADE, Marc

in In Situ (1993), 17(1), 83-104

In order to simulate the cavity growth of an underground gasifier in thin seams, at great depth, Wilks1,2 has developed an original model based on the distribution of fluid flows around an injection well ... [more ▼]

In order to simulate the cavity growth of an underground gasifier in thin seams, at great depth, Wilks1,2 has developed an original model based on the distribution of fluid flows around an injection well. In this paper, we aim to introduce within this model a description of chemical processes on the wall and within the fluid phase, in order to determine the temperature and concentration profiles along the coal wall. These profiles are dependent only on two factors: the transfer coefficients and the energy balance of the gas generator. A study of the sensitivity of the operating variables has been carried out. [less ▲]

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See detailSédimentologie et diagenèse des monticules micritiques "F2j" du Frasnien de l'Ardenne
Boulvain, Frédéric ULg

in Professional Paper Belgian Geological Survey (1993), 260(1 et 2), 1-427

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See detailPresence Of Growth Hormone-Binding Proteins In Cattle Plasma And Milk
Devolder, A.; Renaville, Robert ULg; Sneyers, M. et al

in Journal of Endocrinology (1993), 138(1),

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See detailA model for the origin and petrogenesis of the red stromatactis limestone of Paleozoic carbonate mounds
Bourque, P. A.; Boulvain, Frédéric ULg

in Journal of Sedimentary Petrology (1993), 63(4), 607-619

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See detailCompte-rendu de J. Cerny : Papyrus hiératiques de Deir-el-Médineh
Winand, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1993), 78

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See detailDe l'emploi des tests dans l'expertise psychologique
Mormont, Christian ULg

in Bulletin de Psychologie (1993), 47(415), 235-239

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See detailThyrotropin-releasing hormone and epidermal growth factor induce human prolactin expression via identical multiple cis elements
Berwaer, Monique; Peers, Bernard ULg; Nalda, Asuncion M et al

in Molecular & Cellular Endocrinology (1993), 92(1), 1-7

Pituitary GH3 cells were transfected with different deletion mutants of the human prolactin (hPRL) promoter fused to the CAT reporter gene. The proximal region (-250 to -42) was sufficient to confer ... [more ▼]

Pituitary GH3 cells were transfected with different deletion mutants of the human prolactin (hPRL) promoter fused to the CAT reporter gene. The proximal region (-250 to -42) was sufficient to confer stimulation by both thyrotropin-releasing hormone (TRH) and epidermal growth factor (EGF). Further deletion analyses demonstrated the importance of the three proximal Pit-1 binding sites in this response. However, Pit-1 binding oligonucleotides confer neither TRH nor EGF induction to a linked neutral promoter, suggesting that other elements might be involved. We have previously shown that sequence A (-115 to -85) is needed together with Pit-1 binding sites for full cyclic AMP response of hPRL-CAT. Mutation of this sequence strongly affects TRH and EGF induction. On the other hand, three copies of sequence A confer both TRH and EGF response to a linked neutral promoter. In conclusion, although TRH and EGF activate mostly different intracellular pathways, they mediate transcriptional induction of the hPRL promoter via identical cis elements. [less ▲]

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See detailLa transcription du nominatif -wn dans les noms propres grecs des inscriptions latines de Rome
Purnelle, Gérald ULg

in Revue. Informatique et Statistique dans les Sciences Humaines (1993)

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See detailLa compétence du juge des référés en cas de procédure d'extradition
Kefer, Fabienne ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1993)

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See detailEscherichia coli productrices de la toxine cytotoxique nécrosante de type 1 (CNF1) isolées à partir de processus pathologiques chez des chats et des chiens
Pohl, P.; Mainil, Jacques ULg; Devriese, L. et al

in Annales de Médecine Vétérinaire (1993), 137

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See detailStimulation of the 92-Kd Type Iv Collagenase Promoter and Enzyme Expression in Human Melanoma Cells
Lauricella-Lefebvre, M. A.; Castronovo, Vincenzo ULg; Sato, H. et al

in Invasion & Metastasis (1993), 13(6), 289-300

The 92-kD type IV collagenase is a member of the metalloproteinase family which degrades type IV collagen, a major component of basement membrane and is involved in tumor invasion and metastasis. The ... [more ▼]

The 92-kD type IV collagenase is a member of the metalloproteinase family which degrades type IV collagen, a major component of basement membrane and is involved in tumor invasion and metastasis. The promoter and adjacent regulatory sequences of the 92-kD type IV collagenase have been identified previously and three cis-acting elements homologous to the binding sites for AP-1, NF-KB and SP-1 proteins contributed to induction of the promoter activity by 12-O-tetradecanoylphorbol 13-acetate (TPA) and tumor necrosis factor (TNF-alpha) in HT1080 cells. To date, no direct correlation between promoter activity and expression of the 92-kD type IV collagenase has been reported in normal or cancer cells. In this study, the effects of the transcriptional stimulation of the 92-kD type IV collagenase gene on the expression of the enzyme in human A2058 melanoma cells was analyzed by zymography experiments. Quantitative immunoblots using a monoclonal antibody that recognized specifically and exclusively the 92-kD type IV collagenase, confirmed that the 92-kD gelatinase was 92-kD type IV collagenase. Stimulation of the promoter activity resulted in increased gelatinase activity in the culture medium of A2058 cells. A direct correlation between TPA- and TNF-alpha-mediated promoter stimulation of the 92-kD type IV collagenase gene and its expression was also demonstrated in the human fibrosarcoma HT1080 cells. Interleukin-1 alpha failed to induce 92-kD gene promoter activity and type IV collagenase expression in melanoma and fibrosarcoma cell lines. Our data demonstrated that TPA- and TNF-alpha-induced 92-kD type IV collagenase promoter stimulation leads to a proportional increase of enzyme expression and secretion and thus could contribute to the activation of the invasive phenotype. [less ▲]

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See detailUsing Partial Orders for the Efficient Verification of Deadlock Freedom and Safety Properties
Godefroid, Patrice; Wolper, Pierre ULg

in Formal Methods in System Design (1993), 2(2), 149--164

This article presents an algorithm for detecting deadlocks in concurrent finite-state systems without incurring most of the state explosion due to the modeling of concurrency by interleaving. For systems ... [more ▼]

This article presents an algorithm for detecting deadlocks in concurrent finite-state systems without incurring most of the state explosion due to the modeling of concurrency by interleaving. For systems that have a high level of concurrency, our algorithm can be much more efficient than the classical exploration of the whole state space. Finally, we show that our algorithm can also be used for verifying arbitrary safety properties. [less ▲]

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See detailLes stratégies de développement des villes européennes. Essai de bilan
Merenne-Schoumaker, Bernadette ULg

in Cahiers de Géographie du Quebec (1993), 37(100), 165-168

Reflections on new policies of the European cities for their development

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See detailLes colibacilloses dans l'espèce bovine
Mainil, Jacques ULg

in Annales de Médecine Vétérinaire (1993), 137

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See detailLa descendance de celt. *AKARNOS en wallon
Boutier, Marie-Guy ULg

in Revue de Linguistique Romane (1993)

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See detailEscherichia coli producing CNF1 and CNF2 cytotoxins in animals with different disorders
Pohl, P.; Oswald, E.; Van Muylem, K. et al

in Veterinary Research (1993), 24

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See detailCarbohydrate-deficient glycoprotein syndrome type II.
Jaeken, J.; De Cock, P.; Stibler, H. et al

in Journal of inherited metabolic disease (1993), 16(6), 1041

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See detailCompte rendu de F. Kudlien, R.J. Durling, Galen's Method of Healing, Leiden, 1991
Marganne, Marie-Hélène ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1993), 62

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See detailAssociation between the effacing (eae) gene and the Shiga-like toxin-encoding genes in Escherichia coli isolates from cattle
Mainil, Jacques ULg; Jacquemin, E.; Kaeckenbeeck, A. et al

in American Journal of Veterinary Research (1993), 54

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See detailRaoul de Cambrai.
Moreno, Paola ULg

in Revue Belge de Philologie et d'Histoire (1993)

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See detailTests simples pour le diagnostic présumé des Escherichia coli isolées principalement chez les bovins et productrices des cytotoxines nécrosantes (CNF)
Pohl, P.; Oswald, E.; Van Robaeys, G. et al

in Annales de Médecine Vétérinaire (1993), 137

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See detailCompte rendu de B. Einarson, G.K.K. Link, Theophrastus. De causis plantarum. Books III-IV and V-VI, Cambridge-London, 1990
Marganne, Marie-Hélène ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1993), 62

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See detailLes pseudo-asthmes. Tout ce qui siffle n'est pas asthme.
CORHAY, Jean-Louis ULg; Bury, Thierry ULg; Cabut, Christian ULg et al

in Revue Médicale de Liège (1993), 48(3), 137-42

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See detailLa fonction centrale du thymus dans la reconnaissance des fonctions neuroendocrines par les lymphocytes T au cours de leur développement
Geenen, Vincent ULg; Martens, Henri ULg; Cormann-Goffin, N. et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1993), 101(4, Jul-Aug), 19-22

The dual physiological role of the thymus in T cell positive and negative selection appears prominent in the establishment of appropriate host immune defenses. However, the cellular and molecular ... [more ▼]

The dual physiological role of the thymus in T cell positive and negative selection appears prominent in the establishment of appropriate host immune defenses. However, the cellular and molecular mechanisms underlying those thymic functions begin only to be understood. On the basis of our previous investigations about the thymic expression of different neuroendocrine-related signals, we have advanced a model which transposes at the peptide level the intervention of this primary lymphoid organ in both T cell positive and negative selective processes. There is now ample evidence that the thymic subcapsular and medullary epithelium is the site for synthesis of neurohypophysial (NHP)-related peptides (reviewed in Geenen et al., 1992a). We have also demonstrated that the epithelial component of thymic "nurse" cells (TNC) synthesizes NHP-related peptides and expresses a neuroendocrine-like phenotype (Geenen et al., 1988a). This observation was a remarkable example of the intimate neuroendocrine-immune interactions that take place during T cell ontogeny. Further immunocytochemical analyses have confirmed that one dominant NHP-related epitope belongs to the oxytocin (OT) lineage of the NHP peptide superfamily (Robert et al., 1991, 1992). The intrathymic coexpression of this OT-like epitope with a neurophysin protein domain is a strong argument for a local synthetic process similar to the hypothalamo-NHP one. However, the absence of ir-OT in secretory granules of thymic epithelial cells (TEC), as well as of NHP-related peptides in the supernatant of TEC cultures questioned the application to the thymus of the classical neurosecretory model established for hypothalamic magnocellular neurons (Scharrer [less ▲]

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See detailMonads and chaos : the vitality of Leibniz's philosophy
Bouquiaux, Laurence ULg

in Diogenes (1993)

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See detailEnvironnement socio-géographique et état de santé de la population liégeoise
Gosset, Christiane ULg

in Le journal du Réseau Villes-Santé - Réseau français (1993), 4

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See detailDémocratie, discussion et écriture chez Habermas et Lyotard
Delruelle, Edouard ULg

in Cahiers Internationaux de Symbolisme (1993), 74-76

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See detailThe distensibility of the central bronchial system in calves measured by means of the monofrequency oscillation technique
Reinhold, P.; Barnikol, W. K. R.; Lekeux, Pierre ULg

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (1993), 40

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See detailMédiastinites: diagnostic, facteurs de risque et traitement
Medot, M.; Fissette, J.; Limet, Raymond ULg

in Annales de Chirurgie (1993), 47(8), 752-65

The authors review the literature concerning post-sternotomy mediastinitis. The incidence, mortality, diagnosis and risk factors are discussed, but above all, the various treatments are reviewed and ... [more ▼]

The authors review the literature concerning post-sternotomy mediastinitis. The incidence, mortality, diagnosis and risk factors are discussed, but above all, the various treatments are reviewed and compared with respect to their advantages and risks, their respective usefulness and results, in order to define a reasonable way of management of this highly pejorative surgical complication. Open technique, closed irrigation and surgical flaps of omentum, pectoralis major and rectus abdominis are successively considered. [less ▲]

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See detailSpelling en spellingverandering : een slingerbeweging in de tijd
Vromans, Joseph ULg

in Nederlands van Nu (1993), 41

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See detailThree-dimensional General Circulation Model of the Northern Bering Sea’s Summer Ecohydrodynamics
Nihoul, Jacques ULg; Adam, Paul; Brasseur, Pierre et al

in Continental Shelf Research (1993), 13(5-6), 509-542

The main features of the northern Bering Sea's summer ecohydrodynamics are investigated with the help of two three-dimensional—direct and inverse—models developed at theGeoHydrodynamics ... [more ▼]

The main features of the northern Bering Sea's summer ecohydrodynamics are investigated with the help of two three-dimensional—direct and inverse—models developed at theGeoHydrodynamics andEnvironmentResearch Laboratory of the University of Liège (GHER). Each model consists of two interacting sectorial submodels for (i) the general circulation hydrodynamics and synoptic structures, and (ii) the associated plankton ecosystem dynamics. The direct model is used to simulate, from an initial state compatible with historical, climatological and all available data pertinent to the summer season, a typical overview of the northern Bering Sea's ecohydrodynamics during the summer. The inverse model is applied in a two-fold perspective: (i) the reconstruction of typical summer distributions of temperature and salinity by using more than 1500 CTD profiles measured during the months of July, August and September, in the course of the ISHTAR program; (ii) considering the observations from specific ISHTAR surveys as quasi-synoptic, the reconstruction of individual data fields in order to provide additional information to assess the variability of the system. The model's predictions indicate that the summer dynamics are dominated by a few cogent semi-permanent and reproducible mechanisms which govern the main water mass transports, the upwellings, the fronts and the subsequent seasonal patterns of primary and secondary productions. The general circulation fields calculated by the direct model are considered as a standard of reference to give a coherent interpretation of—local and often instantaneous—observations, process studies and related results, in the context of the natural variability of the system. The simulated flow pattern has been validated, using the set of current measurements provided by 1985 and 1986 ISHTAR moorings. The contribution of the Anadyr Stream to the northward transport is reproduced qualitatively and quantitatively. The vertical motions—undetectable from direct experiments—are computed by the model, and represent one of the most efficient constraints on the ecohydrodynamics. For instance, the strong upwelling located along the Siberian coast—the existence of which was only presumed until recently—is now correctly estimated in position and intensity. The exceptionally high concentrations of nutrients found in the upwelled water turn this hydrodynamic structure into a catalyst element for the development of biological species in the region. The pattern of primary production shows two successive maxima: the first appears as a direct consequence of the frontal conditions associated with the Anadyr Stream, whereas the second develops further north, in the Chukchi Sea. The results display a fairly good agreement with the classical descriptions induced from observations, and suggest that the advection-growth coupling is the main physical conditioning factor for biological processes. [less ▲]

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See detailMapping Of B-Neutralizing And T-Helper Cell Epitopes On The Bovine Leukemia-Virus External Glycoprotein Gp51
Callebaut, I.; Voneche, V.; Mager, A. et al

in Journal of Virology (1993), 67(9),

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See detailHypofractionation in retinoblastoma: an increased risk of retinopathy.
Coucke, Philippe ULg; Mirimanoff, R-O; Schmid, C et al

in Radiotherapy & Oncology (1993), 28

Forty-four eyes in 38 children were treated between 1963 and 1991 by external radiotherapy for retinoblastoma. Treatment modalities varied widely during this period; in addition to radiotherapy there was ... [more ▼]

Forty-four eyes in 38 children were treated between 1963 and 1991 by external radiotherapy for retinoblastoma. Treatment modalities varied widely during this period; in addition to radiotherapy there was chemotherapy (16/44), photocoagulation (14/44), and laser therapy or cryotherapy (14/44). Treatment technique and dose fractionation also varied widely; lateral beam technique (39/44) versus anterior or anterior/lateral beam; doses per fraction ranged from 1 to 4.5 Gy, total doses from 30 to 61.5 Gy, and overall times from 22 to 49 days. Patients were followed at 3-month intervals, and actuarial survival at 10 years was 88%, with 62% local control. Ten eyes showed clinical evidence of retinopathy. A multivariate analysis of factors associated with increased risk of retinopathy was carried out using the Cox proportional hazards model and the mixture model of Farewell. The estimated latent time was 17 months (95% confidence interval, 14-20 months). The only factors found to be significantly associated with retinopathy were total dose multiplied by dose per fraction, or total dose normalized to the equivalent total dose in 2-Gy fractions as estimated from the LQ model, and these gave equivalent descriptions. There were trends (not significant) for increased risk of retinopathy when treatments included chemotherapy or photocoagulation, and for decreased risk (also not significant) when cryotherapy was used in conjunction with radiotherapy. No significance could be attached to any of the following: number of sites per eye, Reese-Ellsworth stage, and family history. We conclude that hypofractionation carries a significant risk for retinopathy in the treatment of retinoblastoma. [less ▲]

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See detailPalaeolithic and Mesolithic Research in Belgium, 1993: le Trou Magrite, Huccorgne & l'Abri du Pape
Straus, Lawrence; Otte, Marcel ULg; Cordy, Jean-Marie ULg et al

in Old World Archaeology Newsletter (1993), XVII(1), 17-24

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See detailL’Iynge dans le discours mythique et les procédures magiques
Pirenne-Delforge, Vinciane ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (1993), 6

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See detailLa place de la musique en hôpital de jour
Triffaux, Jean-Marc ULg; Bertrand, Jean ULg

in Psychologie Médicale (1993)

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See detailLa cinétique cellulaire tumorale: aspects cliniques «à la recherche du temps perdu»
Coucke, Philippe ULg; Paschoud, N

in Bulletin du Cancer. Radiothérapie : Journal de la Société Française du Cancer : Organe de la Société Française de Radiothérapie Oncologique (1993), 80(4), 431-437

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See detailThermal conductivity measurements in soil using an instrument based on the cylindrical probe method
Nicolas, Jacques ULg; Andre, Philippe ULg; Rivez, Jean-François et al

in Review of Scientific Instruments (1993), 64(3), 774-780

The article discusses the underlying hypothesis, the limits, the range of application, and the practical operation of a versatile thermal conductivity analyzer based on a transient cylindrical probe ... [more ▼]

The article discusses the underlying hypothesis, the limits, the range of application, and the practical operation of a versatile thermal conductivity analyzer based on a transient cylindrical probe method. The best expected precision for the conductivity determination appears to be ~±10%. A compact analyzer, integrating all the apparatus' components in the same unit, has been specifically designed for environmental research in the field. Calibration received special attention regarding thermal conductivity values in the range 0.1–3 W/mK. The analyzer was tested on seven materials, in field conditions, and discrepancies from published conductivity values did not exceed 9%. Several checks were performed in the laboratory to study the influence of experimental conditions, such as the probe insertion technique. The cylindrical probe method appears well suited to powdered materials, but may also be applied to viscous liquids and solid matter. As an application, the cylindrical probe was used to characterize nine soils from the Belgian Lorraine. After soil analysis in the dry state, thermal conductivity of each sample was determined at different moisture contents. The transient cylindrical probe method proved to be quick and easy, whether in situ or on samples in the laboratory. It is a powerful tool which can map a country's soil thermal properties. [less ▲]

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See detailThe Audiospinal Reaction in Parkinsonian Patients Reflects Functional Changes in Reticular Nuclei
Delwaide, Paul ULg; PEPIN, Jean-Louis ULg; Maertens De Noordhout, Alain ULg

in Annals of Neurology (1993), 33(1), 63-9

Audiospinal facilitation using the soleus H-reflex as a test was compared in 16 control subjects and 23 parkinsonian patients. In the patients, facilitation was significantly reduced during the 75 to 150 ... [more ▼]

Audiospinal facilitation using the soleus H-reflex as a test was compared in 16 control subjects and 23 parkinsonian patients. In the patients, facilitation was significantly reduced during the 75 to 150 msec after the conditioning stimulation. This reduction was seen bilaterally even in patients with a hemisyndrome. It was corrected by L-dopa but not by anticholinergic agents. Facilitation at the 75-msec delay showed an inverse linear correlation with the bradykinesia intensity (r = -0.7, p < 0.01). The results argue in favor of a reduced excitability of the nucleus reticularis pontis caudalis from which a reticulospinal tract emanates as effector of the audiospinal facilitation. This would represent another example of dysfunction of reticular nuclei in Parkinson's disease. [less ▲]

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See detailNeurotransmitter phenotype plasticity in adult dorsal root ganglia neurons
Moonen, Gustave ULg; Delrée, P.; Martin, Didier ULg et al

in Restorative Neurology & Neuroscience (1993), 5

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See detaila new way to solve galloping on bundled lines. A concept, a prototype bytwo years field experience.
Lilien, Jean-Louis ULg; pirotte, pol; smart, Tom et al

in Bulletin Scientifique de l'Association des Ingénieurs Electriciens sortis de l'Institut Electrotechnique Montefiore (1993), 2

that paper introduce a new concept to control galloping on bundle conductors using a dynamic device coupling detuning of frequencies together with some addition in torsional damping.The concept is ... [more ▼]

that paper introduce a new concept to control galloping on bundle conductors using a dynamic device coupling detuning of frequencies together with some addition in torsional damping.The concept is explained, a prototype is tested on actual line and results are presented. [less ▲]

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See detailNitric oxide: a new messenger in the brain.
Bruhwyler, J.; Chleide, E.; Liégeois, Jean-François ULg et al

in Neuroscience & Biobehavioral Reviews (1993), 17(4), 373-84

The important role played by nitric oxide (NO) in the central nervous system has largely been emphasized in the recent literature. It can originate at least from four different sources: the endothelium of ... [more ▼]

The important role played by nitric oxide (NO) in the central nervous system has largely been emphasized in the recent literature. It can originate at least from four different sources: the endothelium of cerebral vessels, the immunostimulated microglia and astrocytes, the nonadrenergic noncholinergic nerve, and the glutamate neuron. NO has been implicated in a large number of pathologies (such as neurotoxicity in Alzheimer's disease and Huntington's disease, cerebral ischemia, stroke, and anxiety) and also in normal physiological functions (such as memory and learning, regulation of the cerebrovascular system, modulation of the wakefulness, mediation of nociception, olfaction, food intake and drinking, regulation of noradrenaline, and dopamine release). The aim of this paper is to review and to integrate the most recent advances in our understanding of the roles of NO in the brain. [less ▲]

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See detailCaractéristiques du nid et du site de nidification chez le grèbe huppé (Podiceps cristatus). Influence sur le succès des éclosions
Marechal, Corinne ULg

in Cahiers d'Ethologie (1993), 13(1), 1-34

The study aimed at determining the influence of nest and nest-site characteristics on breeding success in a population of great Crested grebes (Podiceps cristatus) nesting on an old máeander of the river ... [more ▼]

The study aimed at determining the influence of nest and nest-site characteristics on breeding success in a population of great Crested grebes (Podiceps cristatus) nesting on an old máeander of the river Meuse on the Belgium-Dutch border. Evolution of clutches has been followed during two breeding seasons (1991 and 1992). The features of the nests and the nest-sites have been subjected to a multivariate analysis. It’s difficult to distinguish clearly between successful and unsuccessful nests during the same year. Moreover, most characteristics are not constant any year. Only two parameters seem to have the same effects on nesting success in 1991 and 1992 : the distance from nest to nearest neighbour and the water level in nest site. Nests distant from another nest and in deep water were less successful. Other possible causes of nesting failure have been tackled (investigator disturbance, bad weather conditions, fall of eggs, clutch-destruction by human). [less ▲]

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See detailP. Colon. Inv. 4781 verso: vente d'une esclave
Straus, Jean ULg

in Zeitschrift für Papyrologie und Epigraphik (1993), 98

Edition du contrat de vente d'une esclave. Papyrus grec d'Egypte. Ptolémaïs Euergétis, 3 décmebre 65

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See detailCompte rendu de La Messe de Tournai
George, Philippe ULg

in Moyen Age (Le) (1993)

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See detailHet Craeckhuys van de Bijloke in Gent, dendrochronologische analyse van houtmonsters
Hoffsummer, Patrick ULg; Houbrechts, David

in Stadsarcheologie (1993), 17(4), 24-29

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See detailBPDZ 44: a new and potent activator of ATP-sensitive K+ channels
Lebrun, P.; Pirotte, Bernard ULg; Antoine, M.-H. et al

in Diabetologia (1993), 36

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See detailInfluence of body size on tibial nerve somato sensory evoked potentials in dogs
Poncelet, Luc; Michaux, Charles; Balligand, Marc ULg

in American Journal of Veterinary Research (1993)

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See detailDu bon steak et du bon lait: d'abord interroger le naturel et en percer tous ces secrets
Renaville, Robert ULg; Burny, Arsène; Portetelle, Daniel ULg

in Agricontact (1993), 255

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See detailAmineptine and response timing in the rat
Lejeune, Helga ULg; Hermans, Isabelle ULg; Mocaer, E. et al

in Behavioural Processes (1993), 29

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See detailAn overview of the kinetic parameters of class B beta-lactamases.
Felici, A; Amicosante, G; Oratore, A et al

in Biochemical Journal (1993), 291 ( Pt 1)

The catalytic properties of three class B beta-lactamases (from Pseudomonas maltophilia, Aeromonas hydrophila and Bacillus cereus) were studied and compared with those of the Bacteroides fragilis enzyme ... [more ▼]

The catalytic properties of three class B beta-lactamases (from Pseudomonas maltophilia, Aeromonas hydrophila and Bacillus cereus) were studied and compared with those of the Bacteroides fragilis enzyme. The A. hydrophila beta-lactamase exhibited a unique specificity profile and could be considered as a rather specific 'carbapenemase'. No relationships were found between sequence similarities and catalytic properties. The problem of the repartition of class B beta-lactamases into sub-classes is discussed. Improved purification methods were devised for the P. maltophilia and A. hydrophila beta-lactamases including, for the latter enzyme, a very efficient affinity chromatography step on a Zn(2+)-chelate column. [less ▲]

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See detailDifferential location of nucleic acids within interchromatin granule clusters.
Thiry, Marc ULg

in European Journal of Cell Biology (1993), 62(2), 259-69

We have examined in great detail the distribution of nucleic acids within interchromatin granule clusters in different cell types by means of various immunocytochemical approaches. Using the in situ ... [more ▼]

We have examined in great detail the distribution of nucleic acids within interchromatin granule clusters in different cell types by means of various immunocytochemical approaches. Using the in situ polyadenylate nucleotidyl transferase-immunogold technique for RNA detection or anti-RNA antibodies, we decisively demonstrate the presence of appreciable amount of RNA in clusters of interchromatin granules of untreated cells. Neither the in situ terminal deoxynucleotidyl transferase-immunogold technique nor anti-DNA antibodies, nor the in situ nick-translation technique for DNA detection have revealed any DNA in the interchromatin granule clusters. However, dispersed chromatin sensitive to DNase I are found at the borders and in the close vicinity of interchromatin granule clusters. The results indicate that interchromatin granule clusters should not be nuclear structures directly involved in RNA transcription but rather in some other steps of RNA metabolism. [less ▲]

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See detailLocation of the rRNA gene
Thiry, Marc ULg

in Rice Biotechnology Quarterly (1993), 15

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See detailDifferent Mechanisms of Extracellular Matrix Remodeling by Fibroblasts in Response to Human Mammary Neoplastic Cells
Noël, Agnès ULg; Munaut, Carine ULg; Nusgens, Betty ULg et al

in Invasion & Metastasis (1993), 13(2), 72-81

Human breast tumors are often associated with a fibrotic reaction termed desmoplasia. Tumor cells may indirectly modulate the composition of the extracellular matrix by influencing fibroblast properties ... [more ▼]

Human breast tumors are often associated with a fibrotic reaction termed desmoplasia. Tumor cells may indirectly modulate the composition of the extracellular matrix by influencing fibroblast properties. They may also directly interact with collagen fibrils leading to retraction of the matrix. We have studied in vitro the influence of various human mammary tumor cells on the proliferation rate of normal human fibroblasts and on their level of collagen synthesis, as well as their release of collagenase activity. Interactions between neoplastic cells and collagen matrix were investigated by incorporation of tumor cells in collagen gels (lattices) and measurement of their retraction. All cells tested (HBL100, SW613, SA52, MDA-MB-231, MCF7, MCF7/6, MCF7 ras, BT20 and T47D) were able to modulate the composition of the extracellular matrix by one or several of the mechanisms investigated. Our results also demonstrate an opposite regulation of collagen and collagenase production. The effects on the collagen metabolism and on fibroblast proliferation are probably mediated by soluble cytokines since they are reproduced by incubating the fibroblasts in the presence of medium conditioned by tumor cells. The desmoplastic reaction may thus result from different mechanisms dependent upon tumor cell types. [less ▲]

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See detailInventaire préliminaire sur le patrimoine campanaire de l'église Saint-Servais à Liège
Marganne, Marie-Hélène ULg; Mélard, Marc

in Bulletin de la Société Royale Le Vieux-Liège (1993), 261

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See detailAnalyse des comportements d'entraîneurs de volley-ball pendant des rencontres officielles
Cloes, Marc ULg; Delhaes, Jean-Pierre; Piéron, Maurice

in Sport (1993), 141(1), 16-25

L'observation systématique des comportements des entraîneurs sportifs a connu un réel développement au cours de la dernière décennie. Les études relevées dans la littérature spécialisée peuvent se ... [more ▼]

L'observation systématique des comportements des entraîneurs sportifs a connu un réel développement au cours de la dernière décennie. Les études relevées dans la littérature spécialisée peuvent se regrouper selon leurs objectifs: (1) l'analyse descriptive des comportements d'entraîneurs et de sportifs, parfois de très haut niveau; (2) la comparaison de situations pédagogiques, notamment en observant une même personne exerçant les fonctions d'entraîner et d'enseignant; (3) la comparaison des interventions des entraîneurs en fonction du niveau d'habileté des sportifs qu'ils dirigent; (4) la comparaison du comportement des entraîneurs en fonction des succès ou des échecs de leur équipe. ... [less ▲]

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See detailAccurate f-values of Astrophysical Interest in neutral Carbon
Hibbert, A.; Biémont, Emile ULg; Godefroid, M. et al

in Astronomy and Astrophysics. Supplement Series (1993), 99

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See detailNEOGENE TO QUATERNARY CLAY MINERAL FLUXES IN THE CENTRAL INDIAN BASIN
DEBRABANT, P.; Fagel, Nathalie ULg; CHAMLEY, H. et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (1993), 103(3-4), 117-131

The late Cenozoic clay sedimentation in the Central Indian Basin was investigated by mineralogical analyses of five very long cores (33-49 m long), which were recovered between 1-degrees and 10-degrees-S ... [more ▼]

The late Cenozoic clay sedimentation in the Central Indian Basin was investigated by mineralogical analyses of five very long cores (33-49 m long), which were recovered between 1-degrees and 10-degrees-S along a transect at about 80-degrees-E and compared with data from adjacent ODP and piston cores. Progressive changes occur from North to South, and are especially marked by a decrease of illite and chlorite amounts balanced by increased contents of smectite and kaolinite. These changes arc attributed to a southwards reduction of Himalaya-derived detrital fluxes, and to a correlative augmentation both of smectite reworked from coastal Indian, Indonesian and volcanic submarine sources, and of kaolinite supplied from Australia and blocked by the equatorial divergence. The stratigraphic changes are more diversified than the geographic changes and develop discontinuously. High fluxes of illitic and chloritic materials during the middle-late Miocene reflect major activity of the Himalayan Main Central Thrust. A tectonic relaxation developed during the latest Miocene-early Pliocene, allowing alternating supply of illite-rich and smectite-rich sediments, which suggests periodical changes from distant to more local supply partly controlled by climate and by Indian intraplate deformations. The more abundant and constant amounts of smectite in late Pliocene-early Pleistocene sediments are chiefly attributed to erosion of Indian coastal zones favored by a worldwide sea-level drop. The middle to late Quaternary increase of the illite group resulted from the resumption of the tectonic activity in the Himalaya-Tibet range associated with a general climatic cooling. [less ▲]

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See detailLaparoscopic supracervical (subtotal) hysterectomy (LASH).
Donnez, Jacques; NISOLLE, Michelle ULg

in Journal of Gynecologic Surgery (1993), 9(2), 91-4

The use of laparoscopically assisted vaginal hysterectomy with or without annexectomy has been widely discussed. We report the technique of laparoscopic supracervical (subtotal) hysterectomy (LASH), which ... [more ▼]

The use of laparoscopically assisted vaginal hysterectomy with or without annexectomy has been widely discussed. We report the technique of laparoscopic supracervical (subtotal) hysterectomy (LASH), which was first performed in 1990. Laparoscopic supracervical hysterectomy was carried out in a series of 36 women. The duration time was 60 min in experienced hands. There were no major complications. The feasibility and low morbidity rate of this laparoscopic approach led us to propose LASH in certain indications, particularly in cases of a uterus with multiple submucosal myomas where hysteroscopic therapy is less successful. [less ▲]

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See detailLa régionalisation du droit pénal international
Flore, Daniel ULg; Thomas, F.

in Revue de Droit Pénal et de Criminologie (1993)

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See detailCalcitonins: Newer Routes of Delivery
Reginster, Jean-Yves ULg

in Osteoporosis International : A Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis & the National Osteoporosis Foundation of the USA (1993), 3(Suppl 2), 3-7

Because of its anti-osteoclastic and analgesic properties, calcitonin is a first-line choice in the treatment of several bone diseases characterized by absolute or relative bone resorption. With regard to ... [more ▼]

Because of its anti-osteoclastic and analgesic properties, calcitonin is a first-line choice in the treatment of several bone diseases characterized by absolute or relative bone resorption. With regard to the prevention and treatment of postmenopausal osteoporosis, the chronic nature of the disease and the subsequent long duration of the pharmacological intervention require uncomfortable parenteral administration to be repeated on a long-term basis. Newer routes of administration have therefore been developed. At present the most promising of these are the nasal spray and the rectal suppository. Both routes have been shown to induce significant increases in plasma levels of salmon calcitonin. The ability of salmon calcitonin to cross the nasal mucosa was shown immunologically by the generation of specific anti-salmon-calcitonin antibodies in the plasma. In healthy volunteers these alternative routes of administration do not decrease the anti-osteoclastic activity of calcitonin, as demonstrated by a significant decrease in biochemical parameters that reflect bone turnover. In the prevention and treatment of postmenopausal osteoporosis, as well as in the treatment of Paget's disease of bone, the properties of calcitonins are generally preserved if they are administered non-parenterally. However, the equivalent doses required to sustain the effects of calcitonin have not been fully elucidated. This article reviews the potential benefits of two methods of non-parenteral administration of calcitonins in the prevention and treatment of postmenopausal osteoporosis. [less ▲]

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