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See detailLesions observed on stranded seabirds along the Belgian coast from 1992 to 1995
Jauniaux, Thierry ULg; Brosens, L.; Coignoul, Freddy ULg

in ICES Journal of Marine Science (1997), 54(4), 714-717

From 1992 to 1995, dead seabirds found on Belgian beaches were collected and various tissues of 241 birds were sampled for histopathological, bacteriological, parasitological, and toxicological ... [more ▼]

From 1992 to 1995, dead seabirds found on Belgian beaches were collected and various tissues of 241 birds were sampled for histopathological, bacteriological, parasitological, and toxicological investigations. The most common species examined was the guillemot (Uria aalge). Necropsies revealed cachexia (severe emaciation), acute haemorrhagic gastro-enteropathy and oil contamination in many of these birds. Statistical analyses were performed in order to explore correlations of these with biological parameters such as age, sex, and origin (pelagic or non-pelagic). The pelagic origin of seabirds were associated with the three main findings. Oil contamination was associated with acute gastro-enteropathy and cachexia, and cachexia was more prevalent among juveniles. Finally, cachexia and acute gastro-enteropathy were strongly associated. It is possible that oiled pelagic seabirds become cachectic and die of acute gastro-enteropathy. (C) 1997 International Council for the Exploration of the Sea. [less ▲]

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See detailPratique et importance des principales activités de loisirs chez des jeunes de 12 et 15 ans dans cinq pays européens
Cloes, Marc ULg; Ledent, Maryse; Didier, Pascale et al

in Sport (1997), 159/160

On admet généralement que les loisirs sont devenus une expression du style de vie dans les pays industrialisés. Dans ce contexte, la place qu'ils occupent dans le secteur social et dans le monde ... [more ▼]

On admet généralement que les loisirs sont devenus une expression du style de vie dans les pays industrialisés. Dans ce contexte, la place qu'ils occupent dans le secteur social et dans le monde économique semble croître régulièrement. Les comparaisons interculturelles des activités de loisirs s'avèrent très difficiles en raison des différences enregistrées dans la conception des instruments utilisés dans les enquêtes et dans les intérêts des équipes de recherche. ... [less ▲]

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See detailIdiopathic hypertrophic cranial pachymeningitis mimicking multiple meningiomas: case report and review of the literature.
Deprez, Manuel ULg; Born, Jacques; Hauwaert, Cécile ULg et al

in Acta Neuropathologica (1997), 94(4), 385-9

A case of idiopathic hypertrophic cranial pachymeningitis with an unusual and misleading manifestation is reported. Computed tomography scan, angiographic and magnetic resonance imaging findings were ... [more ▼]

A case of idiopathic hypertrophic cranial pachymeningitis with an unusual and misleading manifestation is reported. Computed tomography scan, angiographic and magnetic resonance imaging findings were suggestive of multiple meningeal neoplasms and a correct diagnosis was made only after meningeal biopsy. This 44-year-old patient had a previous history of an ill-defined systemic disorder associating episcleritis, erythroderma nodosa and multiple peripheral arthritis. We review previous reports of idiopathic cranial pachymeningitis with emphasis on radiological investigation techniques, histopathology and possible dysimmune mechanisms of pathogenesis. [less ▲]

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See detailReliability of the TEC computed using GPS measurements: the problem of hardware biases
Warnant, René ULg

in Acta Geodaetica et Geophysica Hungarica (1997), 32(3-4), 451-459

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See detailFamilial Crohn's Disease: A Study of 18 Families
Franchimont, D.; Belaiche, Jacques ULg; Louis, Edouard ULg et al

in Acta Gastro-Enterologica Belgica (1997), 60(2, Apr-Jun), 134-7

The high frequency of familial Crohn's disease (CD) suggests a genetic predisposition. The most recent data from epidemiology and molecular biology are consistent with a multifactorial, polygenic ... [more ▼]

The high frequency of familial Crohn's disease (CD) suggests a genetic predisposition. The most recent data from epidemiology and molecular biology are consistent with a multifactorial, polygenic inheritance with a possible genetic heterogeneity. The aim of our study was, first to compare familial and sporadic CD on the basis of the type and location of the disease, and age at diagnosis, and second, to evaluate among families, the concordance rate for the type and location of the disease. PATIENTS AND METHODS: 18 families with 2 (n = 16) and 3 (n = 2) affected first degree relatives were studied. They were compared to a population of 154 sporadic CD coming from the same gastroenterology unit. RESULTS: Age at diagnosis was the same in sporadic and familial CD. There was an increased frequency of ileal (p = 0.02), and fibro stenotic (p = 0.005) CD and a decreased frequency of colonic (p = 0.006) and inflammatory (p = 0.02) disease, in familial CD. There was a significant increase in concordance rate for fibrostenotic disease (p < 0.001) and a decrease for inflammatory disease (p < 0.01), among the families. The observed concordance rate for the location of the disease was not significantly different from the expected one. In conclusion, these data suggest that CD may be heterogenous and that different clinical patterns may be determined either by genetic or environmental factors. [less ▲]

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See detailChanging sensitivity to duration in human scalar timing: An experiment, a review, and some possible explanations
Ferrara, André ULg; Lejeune, Helga ULg; Wearden, J. H.

in Quarterly Journal of Experimental Psychology. B, Comparative & Physiological Psychology (1997), 50B

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See detailVrbis-Orbis (Ovide, Fastes, II, 684)
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (1997), 56(3), 551-553

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See detailLa bryoflore d'une forêt alluviale fonctionnelle: la réserve naturelle rhénane de l'Ile de Rhinau (Bas-Rhin, France)
Klein, J. P.; Siebel, H.; Vanderpoorten, Alain ULg

in Mitteilungen des Badischen Landesvereins für Naturkunde und Naturschutz (1997), 16

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See detailParticipation des jeunes Européens aux activités physiques et sportives
Ledent, Maryse; Cloes, Marc ULg; Telama, Risto et al

in Sport (1997), 159/160

Le rôle primordial que jouent les activités physiques et sportives en matière de prévention de plusieurs maladies parfois fatales survenant à l'âge adulte constitue un argument essentiel en faveur d'une ... [more ▼]

Le rôle primordial que jouent les activités physiques et sportives en matière de prévention de plusieurs maladies parfois fatales survenant à l'âge adulte constitue un argument essentiel en faveur d'une pratique régulière de l'effort physique. Ses effets sur la santé, ou plus précisément sur les facteurs de risque chez les adultes, ont suscité l'éveil d'un nombre croissant de chercheurs. ... [less ▲]

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See detailExamen échographique de l'articulation métacarpo-phalangienne. Corrélation signes échographiques - lésions
Denoix, Jean-Marie; Thill, Emanuelle; Houliez, Didier et al

in Pratique Vétérinaire Equine (1997), 29

This paper is the result of an ex-vivo study on ultrasonography of the equine fetlock. Abnormal findings in equine isolated limbs have been compared to macroscopic findings after dissections and ... [more ▼]

This paper is the result of an ex-vivo study on ultrasonography of the equine fetlock. Abnormal findings in equine isolated limbs have been compared to macroscopic findings after dissections and sensitivity and specificity of the technique have been calculated. [less ▲]

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See detailLeaf carbohydrate status in Lolium temulentum during the induction of flowering
Périlleux, Claire ULg; Bernier, Georges ULg

in New Phytologist (1997), 135(1), 59-66

Unifoliated plants of Lolium temulentum L. ev. Ceres, a qualitative long-day grass, were induced to flower by one 24-h long day (LD) or by one 8-h short day (SD) advanced by 1 2 h in the normal regime, so ... [more ▼]

Unifoliated plants of Lolium temulentum L. ev. Ceres, a qualitative long-day grass, were induced to flower by one 24-h long day (LD) or by one 8-h short day (SD) advanced by 1 2 h in the normal regime, so-called 'displaced short day' (DSD). Standard light for SD and DSD was a mixture of fluorescence and incandescence at 400 µmol m2 s-1 whereas the extension period of the 24-h LD was solely incandescence at 10-15 µmol m2 s-1. The DSD system was first characterized by the timings of floral induction, stimulus translocation and apical development. Carbohydrates in the blade tissues and in leaf exudate were analysed comparatively in vegetative and induced plants. Fructans were not detected in the leaf tissues whereas sucrose and starch were found to be present in similar amounts. In SD, their contents exhibited a diurnal fluctuation and were not in large excess. The common change observed during the two inductive treatments was that starch remained at a high level during the LD extension, even though the lighting was unsuitable for photosynthesis, and increased transiently in DSD. Sucrose was the major sugar contained in the leaf exudate. Its content increased when flowering was induced, but not at the same time in the two systems. In LD, sucrose exudation rose when plants were returned to standard light after the inductive cycle, i.e. after the LD stimulus had left the leaf blade. By contrast, during the DSD, sucrose was transported at the same time as the floral stimulus. Results are discussed together with the methods used to time stimulus translocation and their implications. [less ▲]

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See detailSequence Analysis of the Bovine Herpesvirus Type 1 Genes Homologous to the DNA Polymerase (Ul30), the Major DNA-Binding Protein (Ul29) and Icp18.5 Assembly Protein (Ul28) Genes of Herpes Simplex Virus
Meyer, Gilles; Vlcek, C.; Paces, V. et al

in Archives of Virology (1997), 142(1), 89-102

The nucleotide sequence of a 10.5 kb region (map position 0.332 to 0.410) of bovine herpesvirus type 1 (BHV-1) was determined. This region contained three open reading frames (ORFs) homologous to herpes ... [more ▼]

The nucleotide sequence of a 10.5 kb region (map position 0.332 to 0.410) of bovine herpesvirus type 1 (BHV-1) was determined. This region contained three open reading frames (ORFs) homologous to herpes simplex virus DNA polymerase catalytic subunit (DNApol, UL30), major DNA-binding protein (MDBP, UL29) and ICP18.5 assembly protein (ICP18.5, UL28). The BHV-1 DNApol. MDBP and ICP18.5 ORFs were 1246, 1203 and 826 amino acids long with a calculated molecular mass of 134.2 kDa, 124.4 kDa and 86.9 kDa, respectively. They showed a high homology with alphaherpesvirus homologs despite large differences in the G + C content of the UL30-UL28 segment ranging from 44.4% for varicella zoster virus to 71.5% for BHV-1. Particularly well conserved among Alphaherpesvirinae are the putative functional domains of the DNApol and MDBP proteins which are discussed. Phylogenetic analysis revealed that BHV-1 clustered in the Varicellovirus genus with the animal D-type viruses. In this group, the BHV-1 position was shown to vary according to the investigated genes. Indeed, pseudorabies virus clustered with BHV-1 in the DNApol tree but with equine herpesvirus 1 in the ICP18.5 tree. [less ▲]

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See detailJungermannia paroica (Schiffn.) Grolle in the Vosges, new to France
Vanderpoorten, Alain ULg; Sotiaux, André ULg

in Journal of Bryology (1997), 19

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See detailFibres alimentaires chez le chien IV. Effets sur les ingestions, le poids, les matières fécales et sur la digestibilité des nutriments
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141

The present paper summarizes the influence of diets enriched with fibres on voluntary feed intakes, bodyweight changes of dogs and feces. Fibres affect nutrients digestibility by different mechanisms. The ... [more ▼]

The present paper summarizes the influence of diets enriched with fibres on voluntary feed intakes, bodyweight changes of dogs and feces. Fibres affect nutrients digestibility by different mechanisms. The induced changes vary according to the types of fibre-soluble, insoluble or both- and are, on the whole, quite similar with dogs as in other monogastric species. [less ▲]

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See detailMutations in the immunosuppressive peptide of bovine leukema virus affect fusion and infectivity in vivo
GATOT, Jean-Stéphane ULg; Kettmann, Richard ULg; Callebaut-Mornon, Isabelle et al

in Virus Research (1997), 47(2-Special Issue), 103

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See detailPhylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae.
Elmoualij, Benaïssa ULg; Duyckaerts, Claire ULg; Brasseur, Josette ULg et al

in Yeast (Chichester, England) (1997), 13(6), 573-581

The screening of the open reading frames identified in the whole yeast genome has allowed us to discover 34 proteins belonging to the mitochondrial carrier family. By phylogenetic study, they can be ... [more ▼]

The screening of the open reading frames identified in the whole yeast genome has allowed us to discover 34 proteins belonging to the mitochondrial carrier family. By phylogenetic study, they can be divided into 27 subfamilies including ADP/ATP, phosphate and citrate carriers, putative oxoglutarate and GDC carriers and 22 new subfamilies. Topology predictions using the 'positive inside rule' approach have shown that the yeast carriers are similarly oriented with both extremities exposed to the cytosol. In each subfamily, a strict conservation of the charged residues in the six transmembrane alpha-helices is observed, suggesting a functional role for these residues and the existence of 27 functionally distinct carriers. [less ▲]

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See detailLangmuir film balance study of the surface properties of a soluble fraction of milk fat-globule membrane
Innocente, N.; Blecker, Christophe ULg; Deroanne, C. et al

in Journal of Agricultural and Food Chemistry (1997), 45(5), 1559-1563

Viewed from its origin, composition, and physicochemical properties, milk fat-globule membrane (MFGM) appears to act as a good, natural emulsifier and should be also considered as a potential stabilizing ... [more ▼]

Viewed from its origin, composition, and physicochemical properties, milk fat-globule membrane (MFGM) appears to act as a good, natural emulsifier and should be also considered as a potential stabilizing agent in the preparation of certain foods, e.g. creams and emulsions, infant formulas, and reduced-fat products. The present work was undertaken in an attempt to gain further information on the physicochemical properties of MFGM. In particular, the purpose of this study was to determine surface properties of a soluble fraction of MFGM (SFMFGM) using a film balance and to investigate the changes in the surface activity at different temperatures, which may occur during milk cream ripening or during heat and mechanical treatments of dairy products. The results showed that film balance measurements at the air/water interface actually provided a useful method for the study of SFMFGM monolayers. It was deduced from the compression isotherms that the SFMFGM films spread at the air/water interface presented a different behavior when the temperature varied from 4 to 40 degrees C. [less ▲]

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See detailNo-carrier-added asymmetric synthesis of alpha-methyl-alpha-amino acids labelled with fluorine-18
Damhaut, Philippe; Lemaire, Christian ULg; Plenevaux, Alain ULg et al

in Tetrahedron (1997), 53(16), 5785-5796

Various [18F]fluoro aromatic α-methyl-L-amino acids 11 have been synthesized with high enantiomeric purity (ee > 97%). These new radiopharmaceuticals for Positron Emission Tomography (PET), potential ... [more ▼]

Various [18F]fluoro aromatic α-methyl-L-amino acids 11 have been synthesized with high enantiomeric purity (ee > 97%). These new radiopharmaceuticals for Positron Emission Tomography (PET), potential inhibitors of enzymatic functions, were regiospecifically labelled by nucleophilic substitution on trimethylammoniumbenzaldehyde triflate precursors 9. The [18F]fluoro aromatic aldehydes 12 obtained were easily converted to the corresponding [18F]fluorobenzyl halides [13 (X = 1)]. After alkylation of the lithium enolate of (2S,5S)-l-tert-Boc-2-tert-butyl-3,5-dimethyl-imidazolidin-4-one 2, the adducts were cleaved to give, after HPLC purification, various [18F]fluoro-α-methyl amino acid analogs with radiochemical yields of 10% (End of Bombardment, EOB) after a synthesis time of 120 min. The corresponding [19F]fluorinated amino acids 4 and [19F]fluoro intermediates were also prepared. [less ▲]

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See detailA role for Xenopus Gli-type zinc finger proteins in the early embryonic patterning of mesoderm and neuroectoderm
Marine, Jean-Christophe; Bellefroid, Eric J.; Pendeville-Samain, Hélène ULg et al

in Mechanisms of Development (1997), 63(2), 211-25

Gli-type zinc finger proteins play important regulatory roles in vertebrate and invertebrate embryogenesis. In Xenopus, the Gli-type proteins XGli-3 and XGli-4 are first expressed in earliest stages of ... [more ▼]

Gli-type zinc finger proteins play important regulatory roles in vertebrate and invertebrate embryogenesis. In Xenopus, the Gli-type proteins XGli-3 and XGli-4 are first expressed in earliest stages of mesoderm and neural development. Transient transfection assays reveal that XGli-3 and XGli-4 can function as transcription repressors. Counteracting the Gli-protein repressor activity by ectopic expression of a fusion protein that contains the Gli-zinc finger cluster connected to the E1A activator domain in Xenopus embryos results in specific morphological alterations in the developing somites and in the central nervous system. Altered expression characteristics for a broad set of molecular markers highlighting specific aspects of mesodermal and neural differentiation demonstrate an important role for Gli-type zinc finger proteins in the early mesodermal and neural patterning of Xenopus embryos. [less ▲]

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See detailSoil Solution Nitrogen and Cations Influenced by (NH4)2SO4 Deposition in a Coniferous Forest
Carnol, Monique ULg; Ineson, Phil; Dickinson, A. L.

in Environmental Pollution (1997), 97(1-2), 1-10

The effects of chronically enhanced (NH(4))(2)SO(4) deposition on ion concentrations in soil solution and ionic fluxes were investigated in a Picea abies plot at Grizedale forest, NW England. Soil cores ... [more ▼]

The effects of chronically enhanced (NH(4))(2)SO(4) deposition on ion concentrations in soil solution and ionic fluxes were investigated in a Picea abies plot at Grizedale forest, NW England. Soil cores closed at the base and containing a ceramic suction cup sampler were 'roofed' and watered every 2 weeks with bulk throughfall collected in the field. Treatments consisted of the inclusion of living roots from mature trees in the lysimeters and increasing (NH(4))(2)SO(4) deposition (NS treatment) to ambient + 75 kg N ha(-1) a(-1). Rainfall, throughfall and soil solutions were collected every 2 weeks during 18 months, and analysed for major cations and anions. NO(3)(-) fluxes significantly increased following NS treatment, and were balanced by increased Al(3+) losses. Increased SO(4)(2-) concentrations played a minor role in controlling soil solution cation concentrations. The soil exchange complex was dominated by Al and, during the experimental period, cores of all treatments 'switched' from Ca(2+) to Al(3+) leaching, leading to mean [Formula: see text] molar ratios in soil solution of NS treated cores of 0.24. The experiment confirmed that the most sensitive soils to acidification (through deposition or changing environmental conditions) are those with low base saturation, and with a pH in the lower Ca, or Al buffer ranges. [less ▲]

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See detailComplications hepatiques de la chimiotherapie. De la cytolyse banale a la maladie veino-occlusive du foie.
Baron, Frédéric ULg; Beguin, Yves ULg

in Revue Médicale de Liège (1997), 52(2), 93-7

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See detailFreeze-dried resorcinol-formaldehyde gels
Blacher, Silvia ULg; Pirard, René ULg; Pirard, Jean-Paul ULg et al

in Journal of Non-Crystalline Solids (1997), 212(2-3), 250-261

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer ... [more ▼]

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer to micrometer length-scale. Taking a standard freezing rate, we study in detail the influence of the molar ratio resorcinol/catalyst on the texture, This molar ratio is one of the parameters under consideration which can lead to a tailoring of the dried gel texture in order to develop adsorbents or catalyst supports of controlled porosity. Characterization methods include nitrogen adsorption-desorption (including the classical and the fractal interpretations), mercury porosimetry, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and small angle X-ray scattering (SAXS). [less ▲]

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See detailPropriétés des profils de flux d'induction magnétique dans les céramiques supraconductrices
Vanderbemden, Philippe ULg

in Bulletin Scientifique de l'Association des Ingénieurs Electriciens sortis de l'Institut Electrotechnique Montefiore (1997), 2

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See detailPrevalence and characterization of Microsporum canis carriage in cats.
Mignon, Bernard ULg; Losson, Bertrand ULg

in Journal of Medical and Veterinary Mycology : Bi-Monthly Publication of the International Society for Human and Animal Mycology (1997), 35(4), 249-256

In order to determine the prevalence and to characterize the carriage of Microsporum canis in cats, different mycological examinations (including a culture obtained by hair brushing and Wood's light ... [more ▼]

In order to determine the prevalence and to characterize the carriage of Microsporum canis in cats, different mycological examinations (including a culture obtained by hair brushing and Wood's light examination) were performed on 632 animals of different origins. Group 1 comprised 467 healthy pet cats belonging to veterinary students. In this group, prevalence of carriage was 2.1%: eight cats were asymptomatic transient carriers and one cat was an asymptomatic infected animal presenting discrete Wood's-positive lesions disseminated on the whole body that were visible after sedation and clipping. The carriage prevalence was higher (15.7%) in group 2 comprising 134 European cats destroyed in a pound and kept together. In two additional groups of cats, it was shown that an infected cat was responsible for the dissemination of fungal material into its environment including the other in-contact animals. When the active source of fungus was removed, the dissemination stopped, resulting in a decrease in the amount of infective material recovered from both the animal carriers and the environmental surfaces. This was also observed in two experimental groups of guinea pigs. No association between feline immunodeficiency virus infection and the M. canis carriage was observed in a retrospective case-control study performed on group 2. None of these cats was feline leukaemia virus positive. [less ▲]

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See detailZastosowanie ultrasonografii w diagnostyce klinicznej ukladu rozrodczego u bydla
Gajewski, Z.; Hanzen, Christian ULg; Thun, R. et al

in Nowa Weterynaria (1997)

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See detailOrigine sociale et réussite scolaire : un modèle en Chaîne de Markov estimé sur données individuelles belges
Donni, Olivier; Lejeune, Bernard ULg

in Recherches Economiques de Louvain (1997), 63(4), 421-446

Cet article étudie les relations entre l'origine socio-économique des élèves belges et leur parcours scolaire primaire et secondaire. Il repose sur l'hypothèse que le parcours scolaire des élèves peut ... [more ▼]

Cet article étudie les relations entre l'origine socio-économique des élèves belges et leur parcours scolaire primaire et secondaire. Il repose sur l'hypothèse que le parcours scolaire des élèves peut être décrit par un processus de Markov. Sur la base d'un échantillon transversal d'un millier d'enfants, en fonction de variables socio-économiques et pour chacune des années de scolarité obligatoire, les probabilités individuelles de poursuivre un parcours scolaire ''normal'', c.-à-d. sans redoublement ni relégation dans une filière de second choix, sont estimées. Nos résultats montrent que derrière les substantiels taux agrégés de redoublement qui caractérisent le système scolaire belge se cachent en fait de profondes inégalités sociales. [less ▲]

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See detailLa survie des savoirs médiévaux dans la littérature populaire. Le rôle des incunables
Opsomer, Carmélia ULg

in Bulletin de la Société des Bibliophiles liégeois (1997), 23

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See detailNutrient utilisation and particulate organic matter changes during summer in the upper mixed layer (Ross Sea, Antarctica).
Catalano, Giulio; Povero, Paolo; Fabiano, Mauro et al

in Deep-Sea Research Part I, Oceanographic Research Papers (1997), 44(1), 97-112

The relationships among vertical stability, estimated nutrient utilisation and particulate organic matter in the Ross Sea are analysed from data collected during two cruises in the summers of 1987 - 88 ... [more ▼]

The relationships among vertical stability, estimated nutrient utilisation and particulate organic matter in the Ross Sea are analysed from data collected during two cruises in the summers of 1987 - 88 and 1989 - 90. In the upper mixed layer (UML), identified through the vertical stability E(Z(UML)), nutrient consumption is calculated as the difference between the « diluted » nutrient value and the mean calculated from the integrated value in the UML. The nutrient utilisation ratio and E(Z(UML)) are linearly related for E(Z(UML)) < 25, whereas for values > 25, the distribution pattern is more scattered and independent of E(Z(UML)). For E(Z(UML)) > 25, utilisation values were > 4, 0.4 and 10 mmol m-3 for nitrate, phosphate and silicate, respectively. Significant relationships between nutrient depletion and both particulate organic carbon (POC) and particulate protein / particulate carbohydrate ratios (PPRT/PCHO) are found. The analysis of particulate matter distribution vs nutrient utilisation shows that the stations could be divided into two groups having different characteristics. The first group includes coastal stations, where high nutrient utilisation, POC and PPRT / PCHO are typical of areas with high production. In the second group (pelagic stations), nutrient utilisation, POC and PPRT / PCHO are lower. The vertical stability can be used to discriminate among the factors that influence primary production. [less ▲]

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See detailExpérimentation médicale sur l'être humain. Propositions pour un cadre législatif.
Palermini, Patricia ULg; Delfosse, Marie-Luce

in Revue de Droit de la Santé = Tijdschrift voor Gezondheidsrecht (1997), (5), 333-344

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See detailComment se développe le savoir-lire ?
Hindryckx, Geneviève ULg; Lafontaine, Annette ULg

in Point sur la Recherche en Education (Le) (1997), 4

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See detailThe Major Homology Region Of Bovine Leukaemia Virus P24(Gag) Is Required For Virus Infectivity In Vivo
Willems, Luc ULg; Kerkhofs, P.; Attenelle, L. et al

in Journal of General Virology (1997), 78

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See detailLe clonage par transfert de noyau dans l'espèce bovine
Ectors, Fabien ULg; Delval, Alain; Beckers, Jean-François ULg et al

in Annales de Médecine Vétérinaire (1997), 141

A all in vitro cloning technique was developed in wich embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer (re-cloning). Such method ... [more ▼]

A all in vitro cloning technique was developed in wich embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer (re-cloning). Such method permitted to produce 14,5% of morulae and 14,9% of blastocysts after the first and second cycle of nuclear transfer, respectively. The rates of birth obtained after transfer of such embryos were 21,4% and 20,5% for first and second cyle respectively, corresponding to 6 and 5 calves for 28 and 24 transferred embryos. Unfortunately, gestation patholgies and an increase of birth weights were observed. It seems that the in vitro presence of gametes and/or embryos may be responsible of an alteration in the control of gene expression. [less ▲]

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See detailPsychiatrie de liaison:regards sur une pratique de la psychologie médicale en hôpital général
Triffaux, Jean-Marc ULg

in Revue francaise de psychiatrie et de psychologie médicale (1997)

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See detailCortical application of potassium chloride induces the low-molecular weight heat shock protein (Hsp27) in astrocytes.
Plumier, Jean-Christophe ULg; David, Jean-Claude; Robertson, H. A. et al

in Journal of Cerebral Blood Flow & Metabolism (1997), 17(7), 781-90

Spreading depression induces tolerance to ischemic injury, and ischemic tolerance has been associated with expression of heat shock proteins (Hsp). Here we examine Hsp27 expression after KCl-induced ... [more ▼]

Spreading depression induces tolerance to ischemic injury, and ischemic tolerance has been associated with expression of heat shock proteins (Hsp). Here we examine Hsp27 expression after KCl-induced spreading depression. Twenty-minute cortical KCl application induced Hsp27 immunoreactivity in glial fibrillary acidic protein-positive astrocytes of the ipsilateral neocortex. Systemic administration of MK-801 (3 mg/kg) suppressed KCl-induced Hsp27 expression in the parietal cortex. Astrocytes in the posterior cingulate and retrosplenial cortex did not express Hsp27 after KCl application but did express Hsp27 after systemic administration of high dose MK-801 (9 mg/kg). Whereas Hsp27 was usually observed in all layers of the parietal cortex after 5-minute application of KCl, in 2 of 6 rats, Hsp27 was seen in clusters of astrocytes or in astrocytes in the superficial layers I to III of the parietal cortex. We conclude that (1) cortical application of KCl triggered Hsp27 astrocytic expression; (2) astrocytes in the cingulate and retrosplenial cortex responded differently compared with astrocytes of the parietal cortex; (3) Hsp27 expression progressed from small clusters of astrocytes throughout superficial layers of the cortex that joined and recruited astrocytes in deeper layers; (4) several mechanisms induced Hsp27 astrocytic expression. We propose that Hsp27 is involved in spreading depression-induced ischemic tolerance through protection of astrocyte function. [less ▲]

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See detailCo-regulation and physical association of the 67-kDa monomeric laminin receptor and the alpha6beta4 integrin.
Ardini, E.; Tagliabue, E.; Magnifico, A. et al

in Journal of Biological Chemistry (1997), 272(4), 2342-5

The interactions between tumor cells and laminin or other components of the extracellular matrix have been shown to play an important role in tumor invasion and metastasis. However, the role of the ... [more ▼]

The interactions between tumor cells and laminin or other components of the extracellular matrix have been shown to play an important role in tumor invasion and metastasis. However, the role of the monomeric 67-kDa laminin receptor (67LR) remains unclear. We analyzed the regulation of 67LR expression under different culture conditions with respect to the expression of other well characterized laminin receptors. In A431 cells treated with laminin for different time periods, the regulation of 67LR expression correlated with expression of the alpha6 integrin subunit but not with the expression of other laminin receptors. Moreover, cytokine treatment resulted in down-modulated expression of the alpha6 integrin subunit and the 67LR. Co-regulation of the expression of the two receptors was further suggested by the observation that specific down-modulation of the alpha6-chain by antisense oligonucleotides was accompanied by a proportional decrease in the cell surface expression of 67LR. Biochemical analyses indicated co-immunoprecipitation of 67LR and the alpha6 subunit with an anti-alpha6 but not an anti-beta1 monoclonal antibody. Co-regulation of 67LR and alpha6 subunit expression, together with the physical association between the two receptors, supports the hypothesis that 67LR is an auxiliary molecule involved in regulating or stabilizing the interaction of laminin with the alpha6beta4 integrin. [less ▲]

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See detailLe Système d'informations sur la Biodiversité en Wallonie.
Dufrêne, Marc ULg

in Les cahiers des Réserves Naturelles RNOB (1997), 11

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See detailGenetic Diversity In Lima Bean (Phaseolus Lunatus L) As Revealed By Rapd Markers
Fofana, B.; Vekemans, X.; Du Jardin, Patrick ULg et al

in Euphytica (1997), 95(2),

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See detailThe effects of ammonium sulphate deposition and root sinks on soil solution chemistry in coniferous forest soils
Carnol, Monique ULg; Ineson, Phil; Anderson, J. M. et al

in Biogeochemistry (1997), 38

The effects of enhanced (NH4)(2)SO4 deposition on soil solution cation and anion concentrations and annual ionic fluxes were followed using a standardised experimental protocol in six European coniferous ... [more ▼]

The effects of enhanced (NH4)(2)SO4 deposition on soil solution cation and anion concentrations and annual ionic fluxes were followed using a standardised experimental protocol in six European coniferous forests with contrasting soil types, pollution inputs and climate. Native soil cores containing a ceramic suction cup were installed in the field, roofed and watered every two weeks with local throughfall or local throughfall with added (NH4)(2)SO4 at 75 kg NH4+-N ha(-1) a(-1). Living root systems were established in half of the lysimeters. Untreated throughfall NH4+-N deposition at the sites ranged from 3.7 to 29 kg ha(-1) a(-1). Soil leachates were collected at two weekly intervals over 12 months and analysed for volume, and concentrations of major anions and cations. Increases in soil solution NO3- concentrations in response to N additions were observed after 4-9 months at three sites, whilst one sandy soil with high C:N ratio failed to nitrify under any of the treatments. Changes in NO3- concentrations in soil solution controlled soil solution cation concentrations in the five nitrifying soils, with Al3+ being the dominant cation in the more acid soils with low base saturation. The acidification responses of the soils to the (NH4)(2)SO4 additions were primarily related to the ability of the soils to nitrify the added NH4+. pH and soil texture seemed important in controlling NH4+ leaching in response to the treatments, with two less acidic, clay/clay loam sites showing almost total retention of added NH4+, whilst nearly 75% of the added N was leached as NH4+ at the acid sandy soils. The presence of living roots significantly reduced soil solution NO3- and associated cation concentrations at two of the six sites. The very different responses of the six soils to increased (NH4)(2)SO4 deposition emphasise that the establishment of N critical loads for forest soils need to allow for differences in N storage. capacity and nitrification potential. [less ▲]

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See detailNumerical simulation of a quantum particle in a box
Hermann, Raphaël ULg

in Journal of Physics : A Mathematical & General (1997), 30(11), 3967-3975

It is shown how one can get numerical prediction of quantum mechanical particle behaviour without using the Schrodinger equation. The main steps of this development are the non-differentiability ... [more ▼]

It is shown how one can get numerical prediction of quantum mechanical particle behaviour without using the Schrodinger equation. The main steps of this development are the non-differentiability hypothesis, the equations of motion entailed by this hypothesis, and the numerical formulation of a simple one-dimensional problem: the particle in a box. [less ▲]

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See detailCrystallization and preliminary X-ray analysis of bacteriophage lambda lysozyme in which all tryptophans have been replaced by aza-tryptophans
Evrard, Christine ULg; Declercq, Jean-Paul; Fastrez, Jacques

in Acta Crystallographica Section D-Biological Crystallography (1997), D53

After many unsuccessful attempts to crystallize the bacteriophage lambda lysozyme, a mutant where all the tryptophan residues have been replaced by aza-tryptophans has been crystallized by the vapor ... [more ▼]

After many unsuccessful attempts to crystallize the bacteriophage lambda lysozyme, a mutant where all the tryptophan residues have been replaced by aza-tryptophans has been crystallized by the vapor-diffusion method. The crystals are orthorhombic and belong to space group P212121 with cell dimensions a = 73.01, b = 78.80, c = 82.31 Å. Diffraction data were collected using synchrotron radiation sources. Crystals diffract to a resolution of 2.3 Å. Data from two different platinum derivatives were also recorded to 2.8 and 2.5 Å, respectively. [less ▲]

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See detailLes peuplements à graines. Concept, réglementations et mise en oeuvre.
Vanslembrouck, C.; Rondeux, Jacques ULg

in Silva Belgica (1997), 104(4), 17-21

La rentabilité de la propriété forestière qui, dans une large mesure, conditionne la pérennité des forêts gérées intensivement fait de plus en plus l'objet des préoccupations des chercheurs, sylviculteurs ... [more ▼]

La rentabilité de la propriété forestière qui, dans une large mesure, conditionne la pérennité des forêts gérées intensivement fait de plus en plus l'objet des préoccupations des chercheurs, sylviculteurs, gestionnaires et responsables des politiques forestières. Dans ce contexte, lorsqu'il s'agit de la création et de l'enrichissement de peuplements, veiller à respecter la meilleure adéquation possible entre le sol et l'essence n'est pas tout, encore faut-il ensuite utiliser un matériel génétique de qualité en particulier lors de régénérations artificielles. C'est à ce dernier point, et plus particulièrement aux peuplements à graines, que les lignes suivantes sont consacrées. Nous envisagerons successivement ce qu'il convient communément d'entendre par peuplement à graines (§ 2), sa raison d'être (§ 3) et le processus d'identification de celui-ci (§ 4) avant de tirer quelques brèves conclusions. [less ▲]

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See detailMultiple seawater-derived geochemical signatures in Indian oceanic pelagic clays
Fagel, Nathalie ULg; André, Luc; Debrabant, Pierre

in Geochimica et Cosmochimica Acta (1997), 61(5), 989-1008

This paper reports a geochemical study of oceanic clays. Major and trace elements were analyzed on smectite-rich, clay size (<2 mu m) samples, bulk sediments, and leachate residues from the Central Indian ... [more ▼]

This paper reports a geochemical study of oceanic clays. Major and trace elements were analyzed on smectite-rich, clay size (<2 mu m) samples, bulk sediments, and leachate residues from the Central Indian Basin. Sr-Nd isotopes were also studied to investigate their geochemical evolution during transport in the water column, sedimentation, and diagenesis. The region is of special interest because the sedimentation records the interaction between the detrital supply from the Bengal Fan in the north and the biosiliceous input associated with the equatorial divergence in the south. The clay size fractions display extremely variable trace element contents, e.g., [Ba] = 100-5000 ppm, [Sr] = 20-200 ppm, Ce/Ce* = 0.9-3.3, [Nd] = 10-50 ppm. Although in the argillaceous samples, clay size fractions have a similar trace element imprint to the bulk sediment, some major fractionations occur in the biosiliceous samples between the clay and the bulk sediment, especially for Sr and rare earth elements (REE). Three major components may account for the variable geochemical signatures of these pelagic clays. The first component (component A), already identified by Fagel et al. (1994), is characterized by a homogeneous geochemical signature (La-N/Yb-N = 1.03-1.05; Th/Ta = 12.8-21.1; Ba/Th similar to 28) and a nonradiogenic Nd isotopic composition (Nd-143/Nd-144 similar to 0.511880): it traces a detrital Himalayan-derived origin. The two other components display a seawater-derived isotopic composition with global Sr (Sr-87/Sr-86 similar to 0.709060) and regional Indian Ocean Nd(Nd-143/Nd-144 similar to 0.512200) signatures. Both components are enriched in Sr and Ba (Sr similar to 150 ppm, Ba/Th similar to 500), and they are either enriched in light rare earth elements (LREE, e.g., Nd similar to 50 ppm) in the argillaceous sediments (component B) or LREE-depleted (Nd < 20 ppm) in the biosiliceous sediments (component C). The frequent occurrence of micrometric (<5 mu m) Sr-REE-Th enriched barite grains showing three major habits (rhombic, rounded, dendritic) suggests that these biologically-derived mineral phases had a major role in the genesis of components B and C. A strong clay-barite equilibration is deduced from the Post Archean Australian Shales PAAS-like REE patterns of these barites and the Ba enrichment of the clays. We suggest that it results from two successive mechanisms of exchange. First, at the top of the oxygen minimum zone, the microbial-induced decay of organic matter is proposed to trigger a series of trace element transfers between the various particulate-forming components (clays, barites, and decaying organic coatings). This is proposed as the origin of the clay component B: the barite-derived components (Ba, Sr) and the organic-derived positive Ce anomaly are imported to the clay particles while the PAAS signature of the clays is retained by the remaining barite crystals. Second, after settling, the barites are believed to partly dissolve and recrystallize, especially in the anoxic part of the sedimentary column. This diagenetic barite dissolution is proposed as the origin of the clay component C. Copyright (C) 1997 Elsevier Science Ltd. [less ▲]

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See detailPotential of Varicella zoster virus thymidine kinase as a suicide gene in breast cancer cells
Grignet, Christine ULg; Calberg-Bacq, Claire-Michelle

in Gene Therapy (1997), 4

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See detailPlaidoyer pour une expertise entièrement contradictoire en matière pénale
Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1997)

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See detailAntibodies against vaccinia virus do not neutralize extracellular enveloped virus but prevent virus release from infected cells and comet formation
Vanderplasschen, Alain ULg; Hollinshead, M.; Smith, G. L.

in Journal of General Virology (The) (1997), 78(Pt 8), 2041-2048

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See detailClinical characteristics, prognosis and treatment for pelvic cryptorchid seminoma
Li; COUCKE, Philippe ULg; Qian et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 38(2), 351-357

Purpose: To analyze the clinical characteristics, prognosis, and treatment outcome of pelvic cryptorchid seminoma (PCS), and to determine whether whole abdominal-pelvic irradiation for Stage I disease is ... [more ▼]

Purpose: To analyze the clinical characteristics, prognosis, and treatment outcome of pelvic cryptorchid seminoma (PCS), and to determine whether whole abdominal-pelvic irradiation for Stage I disease is necessary. Methods and Materials: From 1958 to 1991,60 patients with PCS were treated at the Cancer Hospital of Chinese Academy of Medical Sciences, Beijing. They presented with a lower abdominal mass and showed a predominance for the right side. A high proportion of patients with PCS [ 26 of 60 (43% )] had metastatic disease, compared to 20% of those with scrotal seminoma, and there was a tendency toward a higher frequency of pelvic nodal metastases. There were 34 Stage I, 6 Stage IIA, 11 Stage IIB, 5 Stage III, and 4 Stage IV patients. Of these 60 patients, 56 underwent laparotomy with or without cryptorchiectomy (37 radical orchiectomy, 7 partial orchiectomy, and 12 biopsy of the primary or cervical node), and 4 cervical node biopsy only. All patients were further treated with radiotherapy, chemotherapy, or a combination of both. Patients with Stage I and II disease received radiotherapy, whereas patients with Stage III and IV were treated with chemotherapy. Results: The overall and disease-free survivals at 5 and 10 years were 92% and 87%, and 88% and 84%, respectively. The 5- and lo-year survivals were 100% for Stage I, 94% and 87% for Stage II, and 56% and 42% for Stage III/IV, respectively @ < 0.05). Volume of irradiation, i.e., whole abdominal-pelvic radiotherapy ( 10 patients), versus hockey-stick encompassing paraaortic, ipsilateral iliac nodes and the primary tumor or tumor bed (17) did not influence outcome in Stage I patients. Five patients relapsed within 2-12 years after treatment, and four of these patients were successfully salvaged. Four patients developed a second malignant tumor and died. Conclusion: Stage I and II PCS can he adequately controlled by radiotherapy regardless of the surgical procedure. Whole abdominal-pelvic irradiation for Stage I and IIA disease is not required, and fields can be limited to the paraaortic, ipsilateral iliac nodes and primary tumor or tumor bed. We recommend platinum-based chemotherapy for Stage IIB-IV PCS. 0 1997 Elsevier Science Inc. [less ▲]

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See detailPhysical activity, obesity, and cardiovascular risk factors in children. The Belgian Luxembourg Child Study II.
Guillaume, Michèle ULg; Lapidus, L.; Bjondorp, P. et al

in Obesity Research (1997), 5(6), 549-56

Physical activity was measured in relation to cardiovascular (CV) risk factors in a randomly selected population of 1028 children from Province de Luxembourg in Belgium, a mainly rural area with a high ... [more ▼]

Physical activity was measured in relation to cardiovascular (CV) risk factors in a randomly selected population of 1028 children from Province de Luxembourg in Belgium, a mainly rural area with a high prevalence of such risk factors among adults and children. Physical activity was estimated as participation in sport activities, a major indicator of leisure-time physical activity in schoolchildren, and physical inactivity was estimated as frequency and duration of television (TV) watching. Boys participated more frequently in sport activities than girls did (p = 0.001). A majority of the children watched TV daily. After age adjustment, bodyweight (girls, p < 0.012; boys, p < 0.027) and, in boys, body mass index (BMI) (p < 0.039) were related to days per week of TV watching. No significant relationships with other CV risk factors remained after adjustments for BMI. In analyses of independent contributions of age, TV watching, and sports activity on CV risk factors, age showed highly significant relationships. In boys, TV showed relationships with BMI (p < 0.04) and (borderline) with systolic blood pressure, independent of age and sports activity, whereas the latter was significantly related to subscapular skinfold (p < 0.04) and (borderline) with triceps skinfold and cholesterol. In girls, no significant independent contributions to risk factor associations were found. The father's education was directly associated with sports activities, whereas the mother being a housewife showed negative relationships to physical activity and positive to TV watching in their children, suggesting socioeconomic influence on the activity patterns of children. Furthermore, registrations suggested less physical activity in the most rural part of the area. It is concluded that children in this mainly rural area watch TV frequently. In boys, physical inactivity, measured both as TV watching and as registrations of sports activities, contributes independently to body fat mass. In girls, no contribution or weaker contributions of physical inactivity were found. This suggests that contributory factors leading to obesity might be different in girls and boys. [less ▲]

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See detailRoquentin et les types sans importance sociale
Denis, Benoît ULg

in Etudes Françaises (1997), XXXIII(3), 105-119

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See detailHydrostatic flattening, core structure, and translational mode of the inner core
Denis, Carlo; Rogister, Yves; Amalvict, Martine et al

in Physics of the Earth & Planetary Interiors (1997), 99(3-4), 195-206

Modern Earth models are constrained by an inertia coefficient y*=J(2)/H approximate to 0.3308 which leads to a so-called 'hydrostatic' flattening f(hyd) approximate to 1/299.9. The latter is in rather ... [more ▼]

Modern Earth models are constrained by an inertia coefficient y*=J(2)/H approximate to 0.3308 which leads to a so-called 'hydrostatic' flattening f(hyd) approximate to 1/299.9. The latter is in rather large disagreement with the observed flattening f approximate to 1/298.3. We show that a more satisfactory value of the inertia coefficient for constraining a standard Earth model is y approximate to 0.332, consistent with a hydrostatic flattening of about 1/298.6. The change of the value of the inertia coefficient from about 0.331 to about 0.332 significantly alters the density structure of the core, notably the density jump at the inner core boundary. It brings, as a by-produce, the hydrostatic values of J(2) and H to better agreement with the observed values than is presently thought, and most probably leads for the Slichter mode to a period of much longer than 5.42 h, which is the value computed for PREM. [less ▲]

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See detailThe glucocorticoid receptor inhibits the human prolactin gene expression by interference with Pit-1 activity
Nalda, Asunción M; Martial, Joseph ULg; Muller, Marc ULg

in Molecular & Cellular Endocrinology (1997), 134(2), 129-37

Glucocorticoids have been shown to inhibit the activity of the human prolactin (hPRL) promoter. Using transient expression experiments in rat pituitary cells, we located the sequence conferring ... [more ▼]

Glucocorticoids have been shown to inhibit the activity of the human prolactin (hPRL) promoter. Using transient expression experiments in rat pituitary cells, we located the sequence conferring glucocorticoid inhibition to a region which contains Pit-1 binding sites, responsible for pituitary-specific expression, but does not seem to contain a glucocorticoid receptor (GR) binding site. Co-transfection experiments in non-pituitary cell lines, using expression vectors for Pit-1 and different mutants of the human GR show that inhibition of the hPRL gene is seen only in the presence of Pit-1 and GR, and that the DNA binding function of the receptor is not required. Immunoprecipitation studies show that either anti-GR or anti-Pit-1 antibodies are able to co-precipitate GR and Pit-1, suggesting an interaction between these factors. We conclude that the activated GR functionally interferes with the pituitary specific factor Pit-1, thereby leading to the observed transcriptional repression. [less ▲]

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See detailGenetics and Inflammatory Bowel Disease: From Association Studies to Wide Genome Screen
Louis, Edouard ULg; Belaiche, Jacques ULg

in Acta Gastro-Enterologica Belgica (1997), 60(3, Jul-Sep), 201-3

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See detailSur la pratique de la localisation implicite dans le Dictionnaire de l'Ouest-wallon d'Arille Carlier
Boutier, Marie-Guy ULg

in Travaux de linguistique et de philologie (1997), 35-36

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See detailCharacterization of CuInTe2 thin films prepared by flash evaporation
Boustani, M.; El Assali, K.; Bekkay, T. et al

in Semiconductor Science & Technology (1997), 12

Thin films of CuInTe2 were grown by flash evaporation. The influence of the substrate temperature Ts during film deposition on the properties of the thin films was examined. CuInTe2 films were ... [more ▼]

Thin films of CuInTe2 were grown by flash evaporation. The influence of the substrate temperature Ts during film deposition on the properties of the thin films was examined. CuInTe2 films were structurally characterized by the grazing incidence x-ray diffraction (GIXD) technique. Investigation by this technique demonstrates that the surface of thin films of CuInTe2 prepared by flash vaporation at Ts > 100 °C exhibits the chalcopyrite structure with additional binary compounds in the surface. However, in the volume the films exhibit the chalcopyrite structure only; no foreign phases were observed. X-ray reflectometry was utilized to evaluate the critical reflection angle bc of CuInTe2 (bCuInTe2 c 0.32°) which permitted us to calculate the density of the films to be 6 g cm−3. The evaporated films were p type and the films deposited at Ts = 100 °C had a resistivity in the range 0.3–2 cm. From optical measurements we have determined the optical energy gap Eg 0.94 eV and the effective reduced mass m*r 0.07me . [less ▲]

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See detailAttitude des élèves face à l'école et au cours d'éducation physique, âge et retard scolaire
Piéron, Maurice; Delfosse, Catherine; Ledent, Maryse et al

in Revue de l'Education Physique (1997), 37(1), 31-41

Le terme motivation fait partie du langage habituel des psychologues, des enseignants, des sportifs,... Nous pourrions continuer cette liste sans parvenir à lui donner un caractère exhaustif. Parfois ... [more ▼]

Le terme motivation fait partie du langage habituel des psychologues, des enseignants, des sportifs,... Nous pourrions continuer cette liste sans parvenir à lui donner un caractère exhaustif. Parfois utilisé de manière abusive, ce concept présente néanmoins des aspects théoriques et pratiques fondamentaux. A la notion de motivation, on associe très fréquemment celle d'attitude. Toutes deux sont définies en référence à l'affect, c'est-à-dire à une impression d'attraction ou de répulsion vis-à-vis d'un objet déterminé. ... [less ▲]

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See detailFrançois Stockmans
Delmer, A; Fairon-Demaret, M; Streel, Maurice ULg

in Annales Académie Royale des Sciences, des Lettres et des Beaux-Arts de Belgique. Notices (1997), 97

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See detailThe effects of shunting sytemic venous blood into the portal circulation. Review, experiences and future perspectives
D'Silva, Milbhor; Wolf, P.; Bonnet, Pierre ULg

in Archives of Hellenic Medecine (1997), 14(3), 246-264

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See detailFirst epidemiological data on pathogenic leptospires isolated on the Azorean islands
Collares-Pereira, Margarida; Korver, H.; Terpstra, W. J. et al

in European Journal of Epidemiology (1997), 13

Insectivores (Erinaceus europaeus) and rodents (Rattus rattus, R. norvegicus and Mus musculus) from different islands of the Azores archipelago were found to carry three distinct Leptospira interrogans s ... [more ▼]

Insectivores (Erinaceus europaeus) and rodents (Rattus rattus, R. norvegicus and Mus musculus) from different islands of the Azores archipelago were found to carry three distinct Leptospira interrogans s.l. serovars (copenhageni, icterohaemorrhagiae and ballum) which have never been previously investigated there. The house mouse and the black rat were the major Leptospira reservoir showing isolation rates ranging from 0% for both species (in Graciosa) to 88 % and 33 %, respectively (in São Miguel). This study also showed that the majority of the animals with positive kidney cultures exhibited specific agglutinins agaibst the isolated strains of Leptospira. The observed isalation rates in the different islands, with a very interesting island variation in prevalence, suggest that small mammals, serving as sylvatic reservoirs of pathogenic leptospires, may represent an important risk to the health of humans and the livestock, particularly in the islands of Terceira and São Miguel. [less ▲]

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See detailImplication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
Gilles, Christine ULg; Polette, M.; Seiki, M. et al

in Laboratory Investigation : Journal of Technical Methods & Pathology (1997), 76(5), 651-60

We have previously demonstrated that fibroblasts and invasive human breast carcinoma (HBC) cells specifically activate matrix metalloproteinase-2 (MMP-2) when cultured on 3-dimensional gels of type I ... [more ▼]

We have previously demonstrated that fibroblasts and invasive human breast carcinoma (HBC) cells specifically activate matrix metalloproteinase-2 (MMP-2) when cultured on 3-dimensional gels of type I collagen but not a range of other substrates. We show here the constitutive expression of membrane-type 1 (MT1)-MMP in both fibroblasts, and invasive HBC cell lines, that have fibroblastic attributes presumably acquired through an epithelial-to-mesenchymal transition (EMT). Treatment with collagen type I increased the steady-state MT1-MMP mRNA levels in these cells but did not induce either MT1-MMP expression or MMP-2 activation in noninvasive breast carcinoma cell lines, which retain epithelial features. Basal MT3-MMP mRNA expression had a pattern similar to that of MT1-MMP but was not up-regulated by collagen. MT4-MMP mRNA was seen in both invasive and noninvasive HBC cell lines and was also not collagen-regulated, and MT2-MMP mRNA was not detected in any of the HBC cell lines tested. These data support a role for MT1-MMP in the collagen-induced MMP-2-activation seen in these cells. In situ hybridization analysis of archival breast cancer specimens revealed a close parallel in expression of both collagen type I and MT1-MMP mRNA in peritumoral fibroblasts, which was correlated with aggressiveness of the lesion. Relatively high levels of expression of both mRNA species were seen in fibroblasts close to invasive tumor nests and, although only focally, in certain areas close to preinvasive tumors. These foci may represent hot spots for local degradation and invasive progression. Collectively, these results implicate MT1-MMP in collagen-stimulated MMP-2 activation and suggest that this mechanism may be employed in vivo by both tumor-associated fibroblasts and EMT-derived carcinoma cells to facilitate increased invasion and/or metastasis. [less ▲]

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See detailPd/SiO2-cogelled aerogel catalysts and impregnated aerogel and xerogel catalysts: Synthesis and characterization
Heinrichs, Benoît ULg; Noville, Francis ULg; Pirard, Jean-Paul ULg

in Journal of Catalysis (1997), 170(2), 366-376

Pd/SiO2 aerogel catalysts have been synthesized by cogelation of tetraethoxysilane with complex Pd2+[NH2-CH2-CH2-NH-(CH2)(3)-Si(OCH3)(3)](2) containing a hydrolysable silyl group. Pd catalysts have also ... [more ▼]

Pd/SiO2 aerogel catalysts have been synthesized by cogelation of tetraethoxysilane with complex Pd2+[NH2-CH2-CH2-NH-(CH2)(3)-Si(OCH3)(3)](2) containing a hydrolysable silyl group. Pd catalysts have also been prepared by impregnation of silica aerogels and xerogels with solutions of this complex or Pd2+(NH3)(4) followed by drying under hypercritical conditions or under vacuum. It appears that, in cogelled samples, the Pd2+ complex acts as a nucleation agent in the formation of silica particles. The resulting catalysts are then composed of completely accessible palladium crystallites with a diameter of about 2.3 nm located inside silica particles with a monodisperse microporous distribution centered on a hydraulic radius of 0.43 nm. The continuous meso- and macropore distribution is located in voids between particles and between aggregates constituted of those particles. In impregnated samples, it appears that Pd particles are located outside SiO2 particles. The relation between the texture of cogelled and impregnated catalysts and their behavior toward sintering has been studied in detail. In cogelled samples, it has been shown that Pd crystallites cannot migrate because they are trapped in the pores of SiO2 particles. These catalysts are sinterproof during hypercritical drying, When Pd crystallites are not trapped inside SiO2 particles, hypercritical drying leads to an extensive sintering of metal particles. During calcination of impregnated catalysts dried under vacuum, sintering occurs to a various extent depending on the support texture. The Pd crystallites size decreases when the pore size distribution is shifted toward the small sizes. (C) 1997 Academic Press. [less ▲]

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See detailWhole organ vascularized cluster heart-thymus allografting : Experiences with a novel experimental model
D'Silva, Milbhor; Antoniou, E.; Howie, A. J. et al

in Cardiovascular Engineering : An International Journal (1997), 2(1), 65-74

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See detailVieillissement normal, démence d'Alzheimer et mémoire de travail
Van der Linden, Martial ULg; Collette, Fabienne ULg; Andrès Bénito, Pilar

in Psychologie Française (1997), 42

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See detailCaractéristiques microbiologiques et organoleptiques du nététu du commerce.
N'dir, B.; Gningue, B. D.; Keita, N. G. et al

in Cahiers Agricultures (1997), 6

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See detailTheoretical study of slope effects in resistivity surveys and applications
Sahbi, Hassan; Jongmans, Denis; Charlier, Robert ULg

in Geophysical Prospecting (1997), 45(5), 795-808

When electric soundings are made over an irregular terrain, topographic effects can influence the values of apparent resistivity and lead to erroneous 1D interpretation. A 3D finite-element method has ... [more ▼]

When electric soundings are made over an irregular terrain, topographic effects can influence the values of apparent resistivity and lead to erroneous 1D interpretation. A 3D finite-element method has been applied to study the topographical effect of a slope on Schlumberger soundings parallel to the strike. When the resistivity survey is performed at the top of the slope, the apparent resistivity values can be two times higher than in the flat-earth case, depending on the angle (alpha) and height (H) of the slope, and on the distance (X) between the sounding and the slope top. The results are presented as nondimensional curves which can be used for evaluating topographic anomalies for any value of the parameters alpha, H and X. It is numerically shown that the topographic effects can be removed from measurements on horizontally layered structures with an irregular earth surface. Real measurements were performed in different geological conditions over an irregular terrain. The correction method based on the nondimensional curves has been applied to the data and has enabled the determination of the correct layered ground configuration using 1D interpretation. [less ▲]

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See detailRéflexions sur l’iconologie de la châsse de saint Remacle
Van den Bossche, Benoît ULg

in Bulletin de la Société d’Art et d’Histoire du Diocèse de Liège (1997), LXII

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See detailOzone-Induced Stimulation of Pulmonary Sympathetic Fibers: A Protective Mechanism against Edema
Delaunois, Annie ULg; Segura, P.; Dessy, Cécile ULg et al

in Toxicology and Applied Pharmacology (1997), 147(1), 71-82

Tropospheric ozone exerts well-described toxic effects on the respiratory tract. Less documented, by contrast, is the ability of ozone to induce protective mechanisms against agents that are toxic to the ... [more ▼]

Tropospheric ozone exerts well-described toxic effects on the respiratory tract. Less documented, by contrast, is the ability of ozone to induce protective mechanisms against agents that are toxic to the lungs. In particular, interactions between ozone and the sympathetic nervous system have never been considered. Using a model of permeability edema in isolated perfused rabbit lungs, we report here that, immediately after exposure of rabbits to 0.4 ppm ozone for 4 hr, the pulmonary microvascular responses to acetylcholine and substance P are completely blocked. Several lines of evidence, including partial inhibition of the ozone-induced protective effect by several drugs (alpha2- and beta-adrenergic antagonists, neuropeptide Y antagonist, guanethidine), measured levels of released catecholamines in blood and urine and the in vitro response of isolated lungs exposed to 0.4 ppm ozone all seem to suggest that ozone can stimulate pulmonary adrenergic fibers and induce the local release of catecholamines and neuropeptide Y, this resulting in transient protection against pulmonary edema. We also showed that, 48 hr after the exposure, ozone increased the baseline microvascular permeability and the response to low concentrations of acetylcholine [less ▲]

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See detailComparison of hindquarter metabolite uptakes in Belgian Blue double-muscled bulls at maintenance or during fattening.
Hornick, Jean-Luc ULg; Van Eenaeme, Christian ULg; Diez, Marianne ULg et al

in Journal of Animal Science (1997), 75(12), 3331-41

Metabolism of muscle growth in the hindquarter was investigated by the arterio-venous difference (AVD) technique in Belgian Blue double-muscled type bulls at maintenance or at fattening. The bulls were ... [more ▼]

Metabolism of muscle growth in the hindquarter was investigated by the arterio-venous difference (AVD) technique in Belgian Blue double-muscled type bulls at maintenance or at fattening. The bulls were fitted with an aortic ultrasonic blood flow probe and with catheters in the aorta and vena cava. They were offered a diet allowing for maintenance (MP) during a period of 15 d, at the end of which measurements were made over 3 d. Bulls were then given a fattening diet (FP) and the measurements were repeated. Arterial blood flow was approximately 1 L/min greater when the bulls were standing than when lying. Blood flow was 2 L/min higher during FP than during MP. The AVD and uptake of glucose were maximal at 1400 and 1600. Uptake of alpha-amino nitrogen decreased immediately after a meal. The increase in glucose from MP to FP fitted very well with the calculated energy needs for muscle growth. The AVD and uptake of alpha-amino nitrogen, total amino acids, and total nonessential amino acids were negative during MP and positive and significantly higher during FP. There was also a significant increase in AVD and uptake of essential and branched-chain amino acids when the bulls were changed from MP to FP. When changing from maintenance to fattening, the incremental glucose and amino acid hindquarter uptake provided energy and supply for muscle protein accretion, respectively. The level of alanine transamination was also sharply reduced. [less ▲]

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See detailThe impact of sperm precedence in malathion resistance transmission in populations of the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae)
Haubruge, Eric ULg; Arnaud, Ludovic; Mignon, Jacques ULg

in Journal of Stored Products Research (1997), 33(2), 143-146

Malathion resistance in the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) is actually a worldwide problem, and studies on resistance transmission are needed to improve ... [more ▼]

Malathion resistance in the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) is actually a worldwide problem, and studies on resistance transmission are needed to improve insecticide resistance management. Females of Tribolium castaneum commonly mate with several males, and the last batch of male sperm preferentially fertilizes subsequent eggs. This phenomenon, a particular form of sexual selection, helps to increase resistance transmission in populations of stored product insects. We confirmed the last male sperm precedence and, in the absence of further matings, examined the evolution of mixed susceptible and malathion-resistant progeny during a 3-month period. The proportion of resistant phenotypes in female progeny was 99.6 and 3%, respectively, after the first mating with a resistant male and the second mating with a susceptible one. When females thus mated twice were isolated from males, the proportion of the resistant phenotype increased to 34.1% after 30 days. From 72 days onwards, this proportion ranged from 14.2 to 29.7%. (C) 1997, Published by Elsevier Science Ltd. [less ▲]

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See detailGluonic content of the scalar meson nonet in a scaled effective Lagrangian
Jaminon, Martine ULg; Van den Bossche, Bruno

in Nuclear Physics A (1997), 619

A scaled SU(3) Nambu-Jona-Lasinio Lagrangian is used to compute the mass of the nine scalar mesons in the vacuum and the mass of the glueball. This chiral model provides a gluonic content to the scalar ... [more ▼]

A scaled SU(3) Nambu-Jona-Lasinio Lagrangian is used to compute the mass of the nine scalar mesons in the vacuum and the mass of the glueball. This chiral model provides a gluonic content to the scalar mesons as well as a quark content to the glueball. It is shown that a suitable choice of the vacuum gluon condensate allows reproduction of the experimental masses of the scalar mesons except for K*0(1430). This choice corresponds to a weak coupling between the gluon and quark condensates, giving f0(1500) or fJ(1710) which is nearly a pure glueball. [less ▲]

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See detailDeux POHLIA méconnus d'Alsace: P.lutescens (Limpr.) Lindb. et P. lescuriana (Sull.) Andrews
Vanderpoorten, Alain ULg

in Bulletin de la Société d'Histoire Naturelle de Colmar (1997), 63

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See detailQuantitative variations of indolyl compounds including IAA, IAA-aspartate and serotonin in walnut microcuttings during root induction
Gatineau, F.; Fouché, J. G.; Kevers, Claire ULg et al

in Biologia Plantarum (1997), 39(1), 131-137

Shoots of the hybrid walnut Juglans nigra x Juglans regia contained serotonin in the micromole range and indole-3-acetic acid (IAA) in the nanomole range. The serotonin level fell by 40 % in 12 h in auxin ... [more ▼]

Shoots of the hybrid walnut Juglans nigra x Juglans regia contained serotonin in the micromole range and indole-3-acetic acid (IAA) in the nanomole range. The serotonin level fell by 40 % in 12 h in auxin (IBA) treated whole shoots and then reincreased to a maximum (50 % over the control) after 36 h. The same pattern was followed in the top portions of the shoot but in the shoot bases, serotonin always remained under the control level. The early decrease of serotonin was correlated with an increase in IAA-aspartate. The early decrease and peaking of the serotonin level preceded and corresponded to the increase and peaking of free IAA in the shoot bases. The initial serotonin pool in treated-to-root shoots might thus suffice for the biosynthesis of IAA and IAA-conjugated compounds. Because of its auxin-like properties, the early serotonin peak might be taken into consideration as an endogenous auxin signal for rooting in the present material. If this turns out to be so, the rooting signal for the shoot bases necessarily should come from the apices. [less ▲]

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See detailTheory of the thermal conductivity of metallic localized spin compounds in a magnetic field (vol 163, pg 153, 1996)
Rassili, Ahmed ULg; Ausloos, Marcel ULg

in Journal of Magnetism & Magnetic Materials (1997), 170(1-2), 241-241

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See detailLes taxanes : un nouvelle classe d'agents cytotoxiques
Jerusalem, Guy ULg; Fillet, Georges ULg

in Médecine et Hygiène (1997), 55

Paclitaxel et docetaxel sont de novueaux agents cytotoxiques qui présentent un mécanisme d'action tout à fait original. Les taxanes favorisent la polymérisation des dimères alpha et bêta de la tubuline et ... [more ▼]

Paclitaxel et docetaxel sont de novueaux agents cytotoxiques qui présentent un mécanisme d'action tout à fait original. Les taxanes favorisent la polymérisation des dimères alpha et bêta de la tubuline et sont responsables d'anomalies stables de la structure des microtubules ainsi que de la formation anarchique de nombreux astères non fonctionnels. Des résultats encourageants sont observés dans le traitement de deuxième ligne d'une grande variété de cancers. La toxicité est acceptable si l'on utilise une prémédication anti-allergique. Le paclitaxel est indiqué dans le traitement de première ligne du cancer ovarien avancé et de deuxième ligne du cancer du sein métastatique réfractaire aux anthracyclines. Le remboursement dans d'autres indications est à l'étude dans les années à venir. [less ▲]

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See detailGenetic Structure Of A Lima Bean Base Collection Using Allozyme Markers
Maquet, A.; Bi, Iz.; Delvaux, M. et al

in Theoretical & Applied Genetics = Theoretische und Angewandte Genetik (1997), 95(5-6),

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See detailAcetaldehyde-induced changes in the monoamine and amino acid extracellular microdialysate content of the nucleus accumbens
Ward, Roberta J.; Colantuoni, Carlo; Dahchour, Abdelkhader et al

in Neuropharmacology (1997), 36(2), 225-232

The effect of an acute intraperitoneal (i.p.) injection of acetaldehyde, 20 mglkg or 100mg/kg, on the microdialysate content of both amino acids and monoamine was studied in the nucleus accumbens (NA) by ... [more ▼]

The effect of an acute intraperitoneal (i.p.) injection of acetaldehyde, 20 mglkg or 100mg/kg, on the microdialysate content of both amino acids and monoamine was studied in the nucleus accumbens (NA) by a microdialysis technique. Acetaldehyde (ACH) which was detectable at levels of 50-130 µmol/g brain tissue 10 min after injection, evoked a significantd ecrease in the extracellular microdialysis dopamine content, which was sustained for the period of the study, i.e. 120 min. Homovanillicacid, HVA, decreased significantly when the lower dose of ACH was administered while dihydrophenylaceticacid, DOPAC, showed no significant change with either dose of ACH during the period of the study. Serotonin levels decreased significantly after both doses of acetaldehyde, with significant increases of its major metabolite, hydroxyindolacetic acid, 5-HIAA, with the higher acetaldehyde dose. Taurine increased significantly, only during the first twenty minutes, after both doses of acetaldehyde, although neither of the excitatory amino acids assayed, glutamate and aspartate, nor the inhibitoryamino acid, GABA, showed any significant changes. Acetaldehyde clearly evokes significant perturbation in the monoamine content of the NA, such changes being the converse to those reported for monoamine after ethanol administration, which might indicate a negative reinforcement effect. [less ▲]

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See detailThe role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids.
El Ouahabi, A.; Thiry, Marc ULg; Pector, V. et al

in FEBS Letters (1997), 414(2), 187-92

We used a 32P-labeled pCMV-CAT plasmid DNA to estimate the DNA uptake efficiency and unlabeled pCMV-CAT plasmid DNA to quantify the CAT activity after transfection of COS cells using each of the three ... [more ▼]

We used a 32P-labeled pCMV-CAT plasmid DNA to estimate the DNA uptake efficiency and unlabeled pCMV-CAT plasmid DNA to quantify the CAT activity after transfection of COS cells using each of the three following cationic compounds: [1] vectamidine (3-tetradecylamino-N-tert-butyl-N'-tetradecylpropionamidine, and previously described as diC14-amidine [1]), [2] lipofectin (a 1:1 mixture of N-(1-2,3-dioleyloxypropyl)-N,N,N-triethylammonium (DOTMA) and dioleylphosphatidylethanolamine (DOPE)), and [3] DMRIE-C (a 1:1 mixture of N-[1-(2,3-dimyristyloxy)propyl]-N,N-dimethyl-N-(2-hydroxyethyl) ammonium bromide (DMRIE) and cholesterol). Surprisingly, a high CAT activity was observed with vectamidine although the DNA uptake efficiency was lower as compared to lipofectin and DMRIE-C. Transmission electron microscopy (TEM) revealed endocytosis as the major pathway of DNA-cationic lipid complex entry into COS cells for the three cationic lipids. However, the endosomal membrane in contact with complexes containing vectamidine or DMRIE-C often exhibited a disrupted morphology. This disruption of endosomes was much less frequently observed with the DNA-lipofectin complexes. This comparison of the three compounds demonstrate that efficient transfection mediated by cationic lipids is not only correlated to their percentage of uptake but also to their ability to destabilize and escape from endosomes. [less ▲]

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See detailChanges in the Distribution Pattern of Galectin-1 and Galectin-3 in Human Placenta Correlates with the Differentiation Pathways of Trophoblasts
Maquoi, Erik ULg; van den Brule, F. A.; Castronovo, Vincenzo ULg et al

in Placenta (1997), 18(5-6, Jul-Aug), 433-9

Human placentation is a complex biological phenomenon that results from precisely regulated interactions between cells and the extracellular matrix. Galectin- 1 and galectin-3 belong to a newly defined ... [more ▼]

Human placentation is a complex biological phenomenon that results from precisely regulated interactions between cells and the extracellular matrix. Galectin- 1 and galectin-3 belong to a newly defined family of galactose-binding lectins that can bind several glycoconjugates such as the basement membrane glycoprotein laminin, and are involved in many biological events including cell adhesion. In this study, the expression of these two galectins in first and third trimester normal human placenta was examined using single and double immunohistochemical staining and specific antibodies for galectins and cytokeratins. Galectin-3 was detected in all trophoblastic lineages including villous cytotrophoblasts and extravillous trophoblasts (trophoblastic cell columns, infiltrating trophoblasts, endovascular trophoblasts and placental bed giant cells). On the contrary, galectin-1 distribution was restricted to endometrium. A reduction of galectin-3 expression was observed from the villous trophoblasts to the trophoblastic cell columns. This pattern correlated with the switch from a proliferative to a migratory phenotype. Galectin-1 and galectin-3 were both detected in maternal decidual cells. Our data demonstrate a specific pattern of galectin-1 and galectin-3 expression in trophoblastic tissue, and suggest these lectins could contribute to cell-cell and cell matrix interactions of trophoblast during placentation. [less ▲]

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See detailComparison between different methods of measurement of momentum and sensible heat fluxes over canopies.
Aubinet, Marc ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(1),

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See detailPhysical activity and cardiovascular risk factors in children. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Bjorntorp, P.

in Obesity Research (1997)

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See detailLe comportement de reproduction du goujon, Gobio gobio, en aquarium
Poncin, Pascal ULg; Jeandarme, J.; Rinchard, J. et al

in Bull. Fr. Pêche Piscic. (1997)

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See detailIUG-/ZOUG- dans une inscription latine écrite en lettres grecques (CIJ I 215)
Rochette, Bruno ULg

in Zeitschrift für Papyrologie und Epigraphik (1997), 115

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See detailCharacterization of non pigmented B16 melanoma cell-derived cytotoxic factors.
Siwek, B.; De Pauw-Gillet, Marie-Claire ULg; Quetin-Leclercq, J. et al

in Chemico-Biological Interactions (1997), 103(1), 59-73

We analyzed and tried to characterize substance(s) responsible for cytotoxic activities detected in culture media conditioned by non pigmented B16 melanoma cells (NPB16). The different cytological tests ... [more ▼]

We analyzed and tried to characterize substance(s) responsible for cytotoxic activities detected in culture media conditioned by non pigmented B16 melanoma cells (NPB16). The different cytological tests used showed that ultrafiltrated conditioned media (CM U1 fraction) contained several cytotoxic factors with a Mw lower than 1000 Da. These factors seemed to act either directly or indirectly on cell membranes, mitochondria, on the cell cycle and on protein and DNA synthesis. A cytotoxic activity could be found even after high dilution of CM U1. These cytotoxic factors were rapidly released by B16 cells in culture, independently of cell confluence. Their activities in the treated cells were also very fast and the cytotoxic effects were irreversible after only a few hours of treatment. These factors were not intermediate products during melanogenesis, neither polyamines, nor proteases. At least one of them seemed to be a small acidic and basic stable peptide without disulfide bounds but not heat stable. The synthesis of at least one of these cytotoxic factors was inhibited by cycloheximide and the cytotoxic activity was partially destroyed by pronase and trypsin, but not by pepsin. The cytotoxicity was not modified by copper complexants or free radical inhibitors (bovine serum albumin (BSA), tyrosine, superoxyde dismutase (SOD), catalase, vitamin E). Furthermore the levels of glutathione peroxydase activity and reduced glutathione did not change after treatment by CM U1 as compared to controls. [less ▲]

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See detailDiagnostic de l'ostéoporose
Devogelaer, JP; Reginster, Jean-Yves ULg; Raeman, F et al

in Medipractice (1997), 21

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See detailMetacognitive Realism: A cognitive Style or a Learning Strategy?
Jans, Véronique; Leclercq, Dieudonné ULg

in British Journal of Educational Technology (1997), 17(1-2),

Identifies metacognitive realism as the accurate assessment by a learner of their knowledge on a subject. Considers whether realism in metacognition is a stable trait, and possible influences. Briefly ... [more ▼]

Identifies metacognitive realism as the accurate assessment by a learner of their knowledge on a subject. Considers whether realism in metacognition is a stable trait, and possible influences. Briefly reviews the literature and experimental evidence and concludes that metacognitive realism is both style and strategy. [less ▲]

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See detailLes pesticides: effets endocriniens et cancérogènes chez l'Homme
Charlier, Corinne ULg; Plomteux, Guy ULg

in Toxicorama (1997), IX

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See detailPost-operative adjuvant therapy for non-small-cell lung cancer
Barthelemy, Nicole ULg; Johnson; Arriagada et al

in Lung Cancer (1997), 17(supp 1),

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See detailLa rhinotrachéite infectieuse bovine : caractéristiques du virus, l'infection et ses manifestations cliniques
Thiry, Etienne ULg; Lemaire, Mylène; Vanderheijden, Nathalie et al

in Bulletin des Groupements Techniques Vétérinaires (1997), 568

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See detailInfestation par Paramphistomum sp. chez le bovin : description d'un premier cas en Belgique
Losson, Bertrand ULg; Cassart, Dominique ULg; Mignon, Bernard ULg

in Annales de Médecine Vétérinaire (1997), 142

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See detailLow Thiamine Diphosphate Levels in Brains of Patients with Frontal Lobe Degeneration of the Non-Alzheimer's Type
Bettendorff, Lucien ULg; Mastrogiacomo, Frank; Wins, Pierre et al

in Journal of Neurochemistry (1997), 69(5), 2005-2010

We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or ... [more ▼]

We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or frontotemporal dementia with five age-, postmortem delay-, and agonal status-matched control subjects. Our results reveal a 40-50% decrease in thiamine diphosphate (TDP) in the cortex of FNAD patients, whereas thiamine monophosphate was increased 49-119%. TDP synthesizing and hydrolyzing enzymes were unaffected. The activity of citrate synthase, a mitochondrial marker enzyme, was decreased in the frontal cortex of patients with FNAD, but no correlation with TDP content was found. These results suggest that decreased contents of TDP, which is essentially mitochondrial, is a specific feature of FNAD. As TDP is an essential cofactor for oxidative metabolism and neurotransmitter synthesis, and because low thiamine status (compared with other species) is a constant feature in humans, a nearly 50% decrease in cortical TDP content may contribute significantly to the clinical symptoms observed in FNAD. This study also provides a basis for a trial of thiamine, to improve the cognitive status of the patients. [less ▲]

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See detailLes hermeneis dans le christianisme primitif. Aux sources du schisme byzantin
Rochette, Bruno ULg

in Byzantion : Revue Internationale des Etudes Byzantines (1997), 67

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See detailSynthesis of resorcinol-formaldehyde aeroels by the freeze-drying methods
Mathieu, Bernard; Michaux, Bernard; Pirard, René ULg et al

in Annales de Chimie Science des Materiaux (1997), 22

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See detailAn Easy Way to Increase the Finite-Sample Efficiency of the Resampled Minimum Volume Ellipsoid Estimator
Croux, Christophe ULg; Haesbroeck, Gentiane ULg

in Computational Statistics & Data Analysis (1997), 25

In a robust analysis, the minimum volume ellipsoid (MVE) estimator is very often used to estimate both multivariate location and scatter. The MVE estimator for the scatter matrix is defined as the ... [more ▼]

In a robust analysis, the minimum volume ellipsoid (MVE) estimator is very often used to estimate both multivariate location and scatter. The MVE estimator for the scatter matrix is defined as the smallest ellipsoid covering half of the observations, while the MVE location estimator is the midpoint of that ellipsoid. The MVE estimators can be computed by minimizing a certain criterion over a high-dimensional space. In practice, one mostly uses algorithms based on minimization of the objective function over a sequence of trial estimates. One of these estimators uses a resampling scheme, and yields the (p + 1)-subset estimator. In this note, we show how this estimator can easily be adapted, yielding a considerable increase of statistical efficiency at finite samples. This gain in precision is also observed when sampling from contaminated distributions, and it becomes larger when the dimension increases. Therefore, we do not need more computation time nor do we lose robustness properties. Moreover, only a few lines have to be added to existing computer programs. The key idea is to average over several trials close to the optimum, instead of just picking out the trial with the lowest value for the objective function. The resulting estimator keeps the equivariance and robustness properties of the original MVE estimator. This idea can also be applied to several other robust estimators, including least-trimmed-squares regression. [less ▲]

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See detailThe Effects of Hypertonic Saline in Healthy and Diseased Animals
Cambier, Carole ULg; Ratz, V.; Rollin, Frédéric ULg et al

in Veterinary Research Communications (1997), 21(5), 303-316

In this review, the pharmacological effects of administering hypertonic solutions to both healthy animals and during experimentally induced diseases are considered with a view to understanding the ... [more ▼]

In this review, the pharmacological effects of administering hypertonic solutions to both healthy animals and during experimentally induced diseases are considered with a view to understanding the mechanisms behind the possible clinical efficacy of such treatment. The review focuses successively on haemorrhagic shock, endotoxic shock and hypokalaemic metabolic alkalosis. How hypertonic saline solutions affect oxygen transport by haemoglobin is also considered. [less ▲]

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See detailDesign for an Ipriflavone Multicenter European Fracture Study
Reginster, Jean-Yves ULg; Bufalino, L.; Christiansen, C. et al

in Calcified Tissue International (1997), 61(Suppl 1), 28-32

In order to investigate the efficacy of ipriflavone (i.p.) on the prevention of vertebral fractures and the effect on bone mineral density (BMD) in women with postmenopausal osteoporosis, a large ... [more ▼]

In order to investigate the efficacy of ipriflavone (i.p.) on the prevention of vertebral fractures and the effect on bone mineral density (BMD) in women with postmenopausal osteoporosis, a large multicentric European study was designed and is presently ongoing. Included in the study were 460 Caucasian, nonobese postmenopausal women aged > 45 and < 75 years, menopaused for at least 12 months. Inclusion was on the basis of a lumbar bone mineral density (BMD) lower than 2 SD compared with healthy women aged 50 years, corresponding to values below 0.860 g/cm2 (antero-posterior measurement) by Hologic QDR 1000. Women with prevalent vertebral fractures were excluded as well as those presenting secondary osteoporosis or having been treated with medications that could affect bone metabolism. This study was designed as a 3-year, double-blind, placebo-controlled, parallel group study that randomized the women to the oral administration of either 3 x 200 mg/day of i.p. or placebo. All patients received a daily supplement of 500 mg calcium. The primary purpose of the study was to evaluate the efficacy of i.p. in preventing vertebral nontraumatic fractures. Fracture is defined here as a > or = 20% decrease in any anterior, central, or posterior T4-L4 vertebral height. Blinded vertebral X-ray readings and vertebral morphometry have been centralized in an independent Center, with standardized evaluation of two experts. Power calculations have been based on the hypothesis that 21% of placebo-treated patients would fracture within 3 years and that treatment with i.p. would lead to a 50% reduction in the incidence of fracture. Statistical tests have been designed to have a power of 80%, with a type I error equal to 5%. Secondary endpoints were changes in vertebral, radial, and femoral BMD. Centralized controls on 100% BMD scans would ensure the good quality of BMD readings. This study should verify the hypothesis that i.p. significantly decreases the risk of vertebral fracture in postmenopausal, osteoporotic women. [less ▲]

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See detailLoss of calcyphosin gene expression in mouse and other rodents
Clément, S.; Dumont, J.; Schurmans, Stéphane ULg

in Biochemical and Biophysical Research Communications (1997), 232

alcyphosine-for calcium binding and regulated by cyclic AMP through phosphorylation protein-is a target of both the cyclic AMP and the Ca(+2)-phophatidylinositol cascades first isolated from dog thyroid ... [more ▼]

alcyphosine-for calcium binding and regulated by cyclic AMP through phosphorylation protein-is a target of both the cyclic AMP and the Ca(+2)-phophatidylinositol cascades first isolated from dog thyroid, and then from rabbit and human brain. Although the exact function of this 24kD protein is unknown, calcyphosine could be implicated in the cross-signaling between these cascades to coordinate cellular proliferation and differentiation. Here, we report the sequence of a pseudogene which is the murine calcyphosine homologue, and demonstrate that it represents the unique sequence homologous to the dog calcyphosine gene in the murine genome. The lack of expression of this murine pseudogene in brain and thyroid-two major sites of dog calcyphosine expression-was extended to 5 other rodents, and suggest the existence of alternative pathway(s) to fill the function of calcyphosine in rodents [less ▲]

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