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See detailAbsolute configuration of N-[(R)-3-methyl-2-butyl]-(S)-2-(6-methoxy-2-naphthyl)-propionamide
Dupont, L.; Khellili, S.; Pirotte, Bernard ULg et al

in Acta Crystallographica (2001), E57

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See detailEvidence of rainbow trout prolactin interaction with its receptor through unstable homodimerisation.
Le Rouzic, Philippe; Sandra, Olivier; Grosclaude, Jeanne et al

in Molecular & Cellular Endocrinology (2001), 172(1-2), 105-13

This study aims to characterise Prolactin receptor (PRLR) in rainbow trout for which no information is available despite the availability of Salmonid PRL preparations. By screening a freshwater rainbow ... [more ▼]

This study aims to characterise Prolactin receptor (PRLR) in rainbow trout for which no information is available despite the availability of Salmonid PRL preparations. By screening a freshwater rainbow trout intestine cDNA library with a probe corresponding to the extracellular domain (ECD) of tilapia PRLR, we have cloned a 2.5 kb insert coding for the PRLR. The mature protein of 614 amino acid residues is similar to PRLR isolated in tilapia and also the long form of mammalian PRLR. Analysis of PRLR gene expression in osmoregulatory organs revealed the presence of a unique transcript, thus confirming the involvement of this hormone in the control of osmoregulation in this fish species. By using surface plasmon resonance (SPR) technology, kinetic measurement of interaction between trout PRL and its receptor ECD was studied. This approach allowed us to demonstrate the formation of a transient, unstable homodimeric complex. This unstability could explain the inability to perform binding experiments using homologous PRL. In contrast, heterologous lactogenic ligands were able to interact through a more stable complex. Whether these characteristics of PRL-receptor interaction in rainbow trout are different to what occurs in tilapia where a homologous radioreceptor assay was developed would require further studies. [less ▲]

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See detailOriginal 2-alkylamino-6-halogenoquinazolin-4(3H)-ones and KATP channel activity
Somers, F.; Ouedraogo, R.; Antoine, M.-H. et al

in Journal of Medicinal Chemistry (2001), 44

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See detailEuthanasia: a law in Belgium?
Damas, François ULg; Damas, Pierre ULg; Lamy, Maurice ULg

in Intensive Care Medicine (2001), 27(10), 1683

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See detailEvaluation of classical NSAIDs and COX-2 selective inhibitors on purified ovine enzymes and human whole blood
De Leval, X.; Delarge, J.; Devel, P. et al

in Prostaglandins, Leukotrienes, and Essential Fatty Acids (2001), 64

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See detailExtended analysis of the spectrum of triply-ionozed Ytterbium (Yb IV) and transition probabilities
Wyart, J.-F.; Tchang-Brillet, W. U. L.; Spector, N. et al

in Physica Scripta (2001), 63

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See detailLe domicile : une notion plurielle
d'Huart, Véronique ULg

in Répertoire notarial (2001), VII

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See detailLe contrôle de la constitutionnalité des lois aux Pays-Bas
Kohl, Benoît ULg

in Chroniques de Droit Public = Publiekrechtelijke Kronieken (2001)

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See detailCriterii de differentiere a unor specii de Veronica
Crisan, Gianina; Tamas, M.; Garbacki, Nancy ULg et al

in Farmacia (2001), 49(6), 67-73

We have tried to establish some criteria to avoid the substitution of Veronica officinalis L; with anti-ulcer and anti-inflammatory activities with other species of the genus Veronica, especially Veronica ... [more ▼]

We have tried to establish some criteria to avoid the substitution of Veronica officinalis L; with anti-ulcer and anti-inflammatory activities with other species of the genus Veronica, especially Veronica chamaedrys L. widely spread and without therapeutic use. We have studied the different histological, anatomical and phytochemical characters for the two species. A rapid method for the identification of both species is the TLC for flavonoids and phenylpropanic compounds was described. Moreover HPLC is useful to detect the presence of acteoside only in Veronica chamaedrys, while Veronica officinalis contains isoacteoside. [less ▲]

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See detailInsémination artificielle des vaches ‘Azawak’ et taurin ‘Gourunsi’ au Burkina Faso
Zongo, M.; Boly, H.; Sawadogo, L. et al

in Tropicultura (2001), 19(2), 75-78

La synchronisation des chaleurs et la fertilité en insémination artificielle des zébus ‘Azawak’ (Bos indicus, n = 66) et des taurins ‘Gourunsi’ (Bos taurus, n = 20) ont été appréciées en zone périurbaine ... [more ▼]

La synchronisation des chaleurs et la fertilité en insémination artificielle des zébus ‘Azawak’ (Bos indicus, n = 66) et des taurins ‘Gourunsi’ (Bos taurus, n = 20) ont été appréciées en zone périurbaine soudano-sahélienne de Ouagadougou au Burkina Faso. La synchronisation a été effectuée avec des implants sous cutanés de progestagène placés sous la peau de l’oreille pendant 10 jours. Le traitement a été complété par l’injection de prostaglandine F2 et de PMSG, respectivement au 8ième et au 10ième jours de la pose de l’implant. Le taux d’œstrus induits observés par l’éleveur était de 94,2% dans les 48 heures qui suivaient le retrait de l'implant. Il variait significativement (P<0,05) selon les groupes zébus ‘Azawak’ et taurins ‘Gourunsi’ (100% et 75%, respectivement). Les taux de fertilité, déterminés par palpation rectale chez les zébus ‘Azawak’ et les taurins ‘Gourunsi’, ont été respectivement 24,2% et 10%. La fertilité a varié selon le moment de l’insémination: lorsque les femelles étaient inséminées 36 à 48 heures après le retrait de l’implant, les taux de fertilité ont été faibles (0 à 12,5% chez les taurins ‘Gourunsi’ et les zébus ‘Azawak’, respectivement). Par ailleurs, lorsque les inséminations étaient réalisées 24 à 36 heures après le retrait de l’implant, les taux de fertilité ont été respectivement de 50% et 42,3%. [less ▲]

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See detailTraçabilité dans la filière viande. 2. Les marqueurs génétiques.
China, B.; Evrard, V.; Noirfalise, R. et al

in Annales de Médecine Vétérinaire (2001), 145

Afin d’assurer une transparence tout le long de la chaîne de transformation de la viande, il faut disposer d’un système de traçabilité performant. La traçabilité administative montre des limites que ... [more ▼]

Afin d’assurer une transparence tout le long de la chaîne de transformation de la viande, il faut disposer d’un système de traçabilité performant. La traçabilité administative montre des limites que l’utilisation de marqueurs génétiques pourrait surmonter. Le génome de chaque individu possède des différences de séquences, à la base du polymorphisme génétique, dont les marqueurs génétiques sont les témoins. Parmi ceux-ci, deux classes semblent s’imposer en matière de traçabilité : les microsatellites et les polymorphismes simple nucléotide. Les microsatellites sont caractérisés par un degré de polymorphisme important avec de nombreux allèles pour un même locus. De plus, leur détection se fait directement par amplification itérative. Techniquement, le problème se pose lors de la détection simultanée de plusieurs microsatellites où le patron obtenu est difficile à interpréter. Les polymorphismes simple nucléotide sont répresentés par des mutations ponctuelles dans la séquence nucléotidique. Ils sont fréquents, stables, répartis de façon aléatoire et généralement bialléliques. La détection se fait soit par hybridation sur des biopuces, soit par spectrométrie de masse ou par d’autres techniques facilement automatisables. Cette automatisation est nécessaire pour pouvoir tester un grand nombre de polymorphismes simultanément sur un grand nombre d’échantillons, permettant ainsi de diminuer les coûts. L’avantage majeur des polymophismes simple nucléotide est le signal binaire obtenu, son désavantage est le caractère population- spécifique de ce type de marqueur. [less ▲]

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See detailmarchés publics et économie sociale: l'union impossible?
Navez, Françoise ULg; Durviaux, Ann-Lawrence ULg

in Actualités du Droit (2001), 2

L'article envisage la question de l'introduction de considérations sociales dans les marchés publics: les obstacles et la technique de la clause sociale.

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See detailRappresentazioni e pratiche Alimentari in Adolescenza. I risultati preliminari di un’analisi del contenuto delle Interviste semistrutturate con il Programma Alceste
D'Amore, Salvatore ULg

in Eating and Weight Disorders [=EWD] (2001), 6(2), 15

Many studies have analysed psychopathological dimensions of relationship that adolescent have with food and body. But few researches have focused attention on links between psychosocial dimensions such as ... [more ▼]

Many studies have analysed psychopathological dimensions of relationship that adolescent have with food and body. But few researches have focused attention on links between psychosocial dimensions such as social representations (Moscovici, S. 1961; Lalhou, S.1995) and adolescent typical practices of eating (with family and peers) and body (diet and sport). This research is aimed to describe and to analyse representations and practices of eating and body of 60 adolescents (30 females, 30 males) equally distributed on high and low social class aged from 14 to 16 years. Hypothesis supposes changes of eating and body representations and practices according to sexe and social class of subjects. A multimethodogical approach was adopted. Data were collected in Avril 1999 in two roman colleges. Qualitative and quantitative instruments were administered in this order: a) associative network (words association), b) semi-structured interviews (18 questions about eating and body ideas and practices), c) body drawing, d) eating family drawing, e) questionnaires (Eating Attitudes Test, Eating Disorders Inventory 2). A preliminary interviews content analysis with ALCESTE (Reinert, M.1993) draw out 8 discourse classes. Four classes are linked to eating representations and practices: a) Eating Family Practice (16,85 %); b) Eating with Friends (8, 61%); c) Eating quantity and preferences (15, 97%); d) Daily meals organisation (7,40%). Others four classes are linked to body representations and practices: e) Eating Problems (20, 13%); f) Body Health and beauty (8,07%); g) Diets and Sports ( 10,86%); h) Food quality (12, 10%). Results show a general picture of eating and body representations and practices. Eating with family is a very important social situation: a script characterised by social actors, rules, actions and contexts is outlined. Food intake control and food preferences seem pregnant dimensions in identity construction process face to family and peers. Naive theories about eating disorders are constructed. Finally diet, sport and food quality seem central in shaping and modelling body. [less ▲]

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See detailIonic or non-ionic contrast media during coronary intervention: does it make a difference?
Legrand, Victor ULg

in European heart journal (2001), 22(5), 353-4

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See detailChanges in peroxidase activity, and level of phenolic compounds during light-induced plantlet regeneration from Eucalyptus camaldulensis Dehn. nodes in vitro
Arezki, Ouoimare; Boxus, Philippe; Kevers, Claire ULg et al

in Plant Growth Regulation (2001), 33(3), 215-219

Node cultures of Eucalyptus camaldulensis Dehn in Petri dishes in vitro under darkness in the presence of an auxin developed meristematic agglomerates (4 to 6 diameter), i.e. dense shoot clusters in which ... [more ▼]

Node cultures of Eucalyptus camaldulensis Dehn in Petri dishes in vitro under darkness in the presence of an auxin developed meristematic agglomerates (4 to 6 diameter), i.e. dense shoot clusters in which outgrowth of numerous successive buds is limited. Similar cultures under a 16 photoperiod produced small green plantlets with reduced leaves often presenting white hypertrophied lenticels and very short roots crowning the stem bases. The use of half-litre glass vials under light allowed direct development of well-developed rooted plantlets, either in the presence of the same auxin or in the presence of a cytokinin. Light favoured an increase in phenolic compounds and a reverse variation of peroxidase activity during the culture cycles. These aspects are discussed in terms of a possible regulation of the endogenous auxin level through a light control of peroxidase activity and the level of phenolic compounds. [less ▲]

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See detailDes escargots et des champignons à la rescousse du développement durable
Libois, Roland ULg; Codjia, J.T.C.

in Parcs & Réserves (2001), 56(4), 46-49

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See detailVesical varices in a patient with portal hypertension.
Gaspar, Yves; Detry, Olivier ULg; de Leval, Jean ULg

in New England Journal of Medicine [=NEJM] (2001), 345(20), 1503-4

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See detailAnatomical characteristics of tension wood and opposite wood in young inclined stems of poplar (Populus euramericana cv ‘Ghoy’)
Jourez, Benoît ULg; Riboux, Alain; Leclercq, André

in IAWA Journal (2001), 22(2), 133-157

Young shoots from poplar cuttings (P. euramericana cv ‘Ghoy’) were artificially inclined to 30° from vertical to quantify the anatomical modifications induced by this gravitational stimulus. At the end of ... [more ▼]

Young shoots from poplar cuttings (P. euramericana cv ‘Ghoy’) were artificially inclined to 30° from vertical to quantify the anatomical modifications induced by this gravitational stimulus. At the end of the growing season, the tension wood tissue (from the upper face of the inclined axis) was compared to the opposite wood tissue (from the lower face), with radial position taken into account. On isolated elements after maceration, fibres and vessels were significantly longer in tension wood tissue. In the cross section, the gelatinous fibres had a smaller radial diameter than normal fibres in opposite wood. Vessel frequency and porosity were significantly lower in tension wood than opposite wood. Solitary vessels in tension wood were less circular in cross section than in opposite wood, but their surface area did not differ. Rays were more numerous in tension wood than opposite wood but their height did not differ between the two tissue types. Finally, there was a negative correlation between the proportion of vessels lumina (lowest in tension wood) and the proportion of fibres lumina including the G layer. The very controlled nature of this experiment (greenhouse, young clonal material, detailed anatomical observations within one growth ring) and the image analysis technology (allowing a large number of observations) enabled us to draw conclusions that may not have been seen in less-controlled experiments and/or those with smaller sample sizes. [less ▲]

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See detailCarbon sinks in temperate forests
Martin, Philippe; Nabuurs, G. J.; Aubinet, Marc ULg et al

in Annual Review of Energy & the Environment (2001), 26

In addition to being scientifically exciting, commercially important, and environmentally essential, temperate forests have also become a key diplomatic item in international climate negotiations as ... [more ▼]

In addition to being scientifically exciting, commercially important, and environmentally essential, temperate forests have also become a key diplomatic item in international climate negotiations as potential sinks for carbon. This review presents the methods used to estimate carbon sequestration, identifies the constraints and opportunities for carbon sequestration in temperate forests, addresses the issues raised by the monitoring of carbon sequestration, and analyzes uncertainties pertaining to the sequestration of carbon by temperate forests. This review serves a dual purpose: It aims at informing policy makers about carbon sequestration in temperate forests and at making forest ecologists, biogeochemists, and atmospheric scientists aware of the structure of an international agreement to reduce CO2 and other greenhouse gas emissions and some of the real, still answered scientific questions that it poses. [less ▲]

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See detailSpectroscopic evidence for high-altitude Aurora at Jupiter from Galileo Extreme Ultraviolet Spectrometer and Hopkins Ultraviolet Telescope observations
Ajello, Joseph M.; Shemansky, D. E.; Pryor, Wayne R. et al

in Icarus: International Journal of Solar System Studies (2001), 152(1), 151-171

The Galileo Extreme Ultraviolet Spectrometer (EUVS) and the Hopkins Ultraviolet Telescope (HUT) acquired UV spectra of Jupiter Aurora in the period from 1995 through 1997, The EUVS spectra spanned the ... [more ▼]

The Galileo Extreme Ultraviolet Spectrometer (EUVS) and the Hopkins Ultraviolet Telescope (HUT) acquired UV spectra of Jupiter Aurora in the period from 1995 through 1997, The EUVS spectra spanned the wavelength range 540-1280 Angstrom and the HUT spectra measured the extreme ultraviolet and far ultraviolet (EUV + FUV) wavelength range 830-1850 Angstrom. Both sets of spectra present evidence of high-altitude, optically thin H-2 band emissions from the exobase region, The analysis of the UV spectra with a two-stream electron transport model and a jovian model auroral atmosphere indicates that the primary electron flux is composed of both soft and hard electrons with characteristic energies in the soft electron energy range of 20-200 eV and the hard electron range of 5-100 keV, The soft electron flux causes enhanced EUV emission intensities below 1100 Angstrom. The soft electron flux may explain the high temperature of the upper atmosphere above the homopause as measured from Il: rovibrational temperatures in the IR. For the deep aurora, a high primary characteristic energy above 5 keV is known to be present. The Galileo Energetic Particle Detector (EPD) has measured the electron distribution functions for energies above 15 keV in the middle magnetosphere. The high-energy distribution functions can be modeled by a combination of Maxwellian and kappa distributions. However, the EUV (800-1200 Angstrom) portion of the HUT spectrum cannot be modeled with a single distribution of hard electrons as was possible in the past for the FUV (1200-1650 Angstrom) spectrum measured by itself, The combination of EUV and FUV spectral observations by HUT serves to identify the amount of soft electron flux relative to the hard primary flux required to produce the high-altitude aurora in the neighborhood of the exobase, (C) tool academic Press. [less ▲]

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See detailA 4-year study of the mycological aspects of Kashin-Beck disease in Tibet
Chasseur, Camille; Suetens, Carl; Michel, Valérie et al

in International Orthopaedics (2001), 25

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See detailResidual circulation and thermohaline distribution of the Ria de Vigo: a 3-D hydrodynamical model
Lopez, S. T.; Varela, R. A.; Delhez, Eric ULg

in Scientia Marina (2001), 65(Suppl. 1), 277-289

A three-dimensional, non-linear, baroclinic model is described and tested for the first time to study the residual circulation and the thermohaline distribution of the Ria de Vigo (NW Spain) at short time ... [more ▼]

A three-dimensional, non-linear, baroclinic model is described and tested for the first time to study the residual circulation and the thermohaline distribution of the Ria de Vigo (NW Spain) at short time scales and under different wind stress regimes. Two markedly different realistic scenarios were chosen: northerly upwelling-favourable winds and southerly downwelling-favourable winds. The numerical experiments carried out indicate that the hydrodynamic regime of the Ria de Vigo is mostly a consequence of wind events. As could be expected, moderately strong North winds reinforce the normal (positive) Ria circulation, while winds blowing from the South, when sufficiently strong, reverse the typical circulation pattern and reduce the characteristic outgoing velocities and the flushing time inside the Ria. The temperature and salinity fields generated by the model in both situations were compared with observations and found to be in qualitatively good agreement, supporting the 3D velocity field distribution. [less ▲]

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See detailCachez cette loi que je ne saurais voir !
Orban, Lionel ULg

in Actualités du Droit (2001)

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See detailL'empreinte unitaire par coffrage métallo-résineux
Francois, Marcelle ULg; Lamy, Marc ULg

in Revue Belge de Médecine Dentaire = Belgisch Tijdschrift voor Tandheelkunde (2001), 56(3), 181-8

The metallic-resinous frame impression technique is based on the impression of single abutments encompassed in a global one, with or without transfert copings. For single tooth impression, this technique ... [more ▼]

The metallic-resinous frame impression technique is based on the impression of single abutments encompassed in a global one, with or without transfert copings. For single tooth impression, this technique is the easiest and the most practical alternative to the one using thermoplastic paste. The aim of this article is to describe, step-by-step, the impression taking procedures using the metallic-resinous frame technique. [less ▲]

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See detailNumeration systems on a regular language : Arithmetic operations, Recognizability and Formal power series
Rigo, Michel ULg

in Theoretical Computer Science (2001), 269

Generalizations of numeration systems in which \(\N\) is recognizable by a finite automaton are obtained by describing a lexicographically ordered infinite regular language \(L\subset \Sigma^*\). For ... [more ▼]

Generalizations of numeration systems in which \(\N\) is recognizable by a finite automaton are obtained by describing a lexicographically ordered infinite regular language \(L\subset \Sigma^*\). For these systems, we obtain a characterization of recognizable sets of integers in terms of $\N$-rational formal series. After a study of the polynomial regular languages, we show that, if the complexity of \(L\) is \(\Theta (n^l)\) (resp. if \(L\) is the complement of a polynomial language), then multiplication by \(\lambda\in \N\) preserves recognizability only if \(\lambda=\beta^{l+1}\) (resp. if \(\lambda\neq (\#\Sigma)^\beta\)) for some \(\beta\in \N\). Finally, we obtain sufficient conditions for the notions of recognizability for abstract systems and some positional number systems to be equivalent. [less ▲]

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See detailHuman - ovine comparative sequencing of a 250 kilobase imprinted domain encompassing the callipyge (clpg) gene and identification of six imprinted transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11 and MEG8
Charlier, Carole ULg; SEGERS, Karin ULg; Wagenaar, D. et al

in Genome Research (2001), 11

Two ovine BAC clones and a connecting long-range PCR product, jointly spanning ∼250 kb and representing most of theMULGE5-OY3 marker interval known to contain the clpglocus, were completely sequenced. The ... [more ▼]

Two ovine BAC clones and a connecting long-range PCR product, jointly spanning ∼250 kb and representing most of theMULGE5-OY3 marker interval known to contain the clpglocus, were completely sequenced. The resulting genomic sequence was aligned with its human ortholog and extensively annotated. Six transcripts, four of which were novel, were predicted to originate from within the analyzed region and their existence confirmed experimentally: DLK1, DAT, GTL2, PEG11, antiPEG11, and MEG8. RT-PCR experiments performed on a range of tissues sampled from an 8-wk-old animal demonstrated the preferential expression of all six transcripts in skeletal muscle, which suggests that they are under control of common regulatory elements. The six transcripts were also shown to be subject to parental imprinting: DLK1, DAT, andPEG11 were shown to be paternally expressed and GTL2,antiPEG11, and MEG8 to be maternally expressed. [less ▲]

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See detailSedimentology of the Bieumont Member : influence of the Lion Member Carbonate mounds (Frasnian, Belgium) on their sedimentary environment
Humblet, M.; Boulvain, Frédéric ULg

in Geologica Belgica (2001), 3(1-2), 97-118

This is a sedimentological study of Middle Frasnian Bieumont Member fore-reef and off-reef carbonate sediments exposed in the Chimay-Couvin region (Belgium). It is based on four stratigraphic sections ... [more ▼]

This is a sedimentological study of Middle Frasnian Bieumont Member fore-reef and off-reef carbonate sediments exposed in the Chimay-Couvin region (Belgium). It is based on four stratigraphic sections: the Lompret quarry, the Frasnes railway section, the Leus quarry and southern parts of the Lion quarry. The Lompret section is here described for the first time and represents the main focus of this work. The Bieumont Member consists of a bedded sequence of argillaceous and bioclastic limestone. At Lompret, the Member is exposed with a thickness of 48 m (the basal contact is not exposed). The Member consists of 6 lithological units (in stratigraphic order) : 1. argillaceous limestone with episodic intercalations of reef debris (distal reef talus), 2. an alternation of marl and argillaceous limestone (basinal background sediment), 3. thickly-bedded bioclastic limestone (channel deposits), 4. a sequence of argillaceous limestone (inter-channel deposits), 5. bioclastic limestone with sporadic occurrence of framestone (proximal fore-reef deposits) and 6. fine-grained, bioclastic limestone interbedded with prominent layers of reef debris (distal fore-reef deposits). Within unit 5, an isolated reef block transported down the paleoslope is present. Microfacies analysis revealed 16 microfacies units which together with the lithological subdivisions were used to reconstruct the dynamic sedimentary history of the Bieumont Member at Lompret. There are two orders of depositional rhythmicity. The reef growth cycle starts with the first significant influx of reef-related facies at the beginning of unit 3 and from thereon is well differentiated from the Bieumont Member stratotype which largely consists of lithologies equivalent to units 1 and 2. Progradation was directed to the South and related shallowing-upward conditions culminated during the deposition of unit 5. On a lower scale, rhythmic bedding within units 2 and 4 could be related to orbitally forced cycling. The vertical and lateral variations of facies within the Bieumont Member were used to reconstruct a depositional model for the Lompret area. In addition, the documentation of facies variation on a regional scale was enhanced by using data from the Focant borehole and geological surveys of Han-sur-Lesse and Barvaux regions. [less ▲]

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See detailL'impact de la readaptation cardiaque sur la qualite de vie apres un pontage aorto-coronaire : Une etude belge
Etienne, Anne-Marie ULg; Fontaine, Ovide ULg; Dupuis, Gilles et al

in Revue Francophone de Clinique Comportementale et Cognitive (2001), 6(2), 15-25

The aim of this study was to measure the quality of life of coronary artery bypass surgery patients enrolled or not in a rehabilitation program. The study was prospective and longitudinal and used ... [more ▼]

The aim of this study was to measure the quality of life of coronary artery bypass surgery patients enrolled or not in a rehabilitation program. The study was prospective and longitudinal and used patients’ self selection as the allocation strategy to constitute the two groups: rehabilitation and no-rehabilitation. Forty first coronary bypass surgery patients (38 men and 2 women, mean age 59 +/-8) were recruited from four hospitals in a French area of Belgium. Patients were evaluated before and after surgery with: the Quality of Life Systemic Inventory (QLSI), the Beck Depression Inventory, the State Anxiety Inventory, a somatic symptoms questionnaire, a physical activities questionnaire, and a medical questionnaire. Both groups improved on the QLSI global score of quality of life, but the effect size (eta squared) was greater in the rehab group (0.5) compared to the no rehab group (0.25) [less ▲]

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See detailDu mode de définition de deux programmes de recherche en sociologie et en ethnométhodologie
Lejeune, Christophe ULg

in Carnets de Bord (2001), 2

Cet article examine la fondation de deux programmes scientifiques via l’étude de leur bibliographie, des traductions qu’ils opèrent et de leur définition de la mauvaise façon de faire science: leur ... [more ▼]

Cet article examine la fondation de deux programmes scientifiques via l’étude de leur bibliographie, des traductions qu’ils opèrent et de leur définition de la mauvaise façon de faire science: leur pathologie. Dans le « métier de sociologue », la cohérence entre l’importation bachelardienne de la rupture épistémologique et la sociologie critique permet de réaffirmer les dangers du substantialisme. L’ethnométhodologie s’offre quant à elle la sociologie comme pathologie. Elle traduit de manière singulière les règles de méthodes de Durkheim et Parsons en phénomènes ordinaires observables et descriptibles. L’analyse de l’opération concrète de fondation des principes de méthode de ces programmes de recherche sociologique offre une occasion d’envisager différemment le rapport de l’action à son contexte, de la sociologie à son objet, de la connaissance scientifique à la connaissance ordinaire. [less ▲]

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See detailVoix de la mémoire et causes obscures
Gauthier, Jean-Marie ULg

in Cahiers de Psychologie Clinique (2001), 16

Freud a établi un lien très fort entre Inconscient et temporalité puisque, à l'inverse de toutes nos autres productions personnelles, seul celui-ci ne subirait pas les outrages du temps. Ce texte tente de ... [more ▼]

Freud a établi un lien très fort entre Inconscient et temporalité puisque, à l'inverse de toutes nos autres productions personnelles, seul celui-ci ne subirait pas les outrages du temps. Ce texte tente de montrer l'importance et la richesse de cette intuition freudienne à travers l'analyse du film de W. Wenders, 'Lisbon Story'. Il nous faut alors, pour reprendre les propos de Freud constater que la structure de nos temporalités intérieures est complexe, à la fois immuable et en perpétuelle transformation. [less ▲]

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See detailLe dispositif d'évaluation externe en Communauté française de Belgique
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 195-218

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See detailDietary habits during adolescence - results of the Belgian Adolux Study
Paulus, Dominique; Saint-Remy, Annie ULg; JeanJean, Michel

in European Journal of Clinical Nutrition (2001), 55

STUDY: To analyse the usual dietary habits of Belgian adolescents from a high cardiovascular risk population. METHODS: A food frequency questionnaire (57 items) was administered to the whole sample ... [more ▼]

STUDY: To analyse the usual dietary habits of Belgian adolescents from a high cardiovascular risk population. METHODS: A food frequency questionnaire (57 items) was administered to the whole sample. Complementary questions specified some types of food (eg fat content). A subgroup of 234 adolescents gave detailed information on portion size (picture book and food samples). SETTING: Twenty-four secondary schools in the Belgian province of Luxembourg. SUBJECTS: A total of 1,526 adolescents (12-17y) selected by a multiclustered stage sampling (participation: 83.6%). RESULTS: Respectively 46% and 60% of the adolescents did not eat fruit and vegetables daily. Most of the adolescents (72%) consumed at least one dairy product daily. The frequent consumption of chocolate and French fries indicated the strong cultural influence on dietary habits while imported foods (like hamburgers) had little success. One-third of the adolescents (33%, n = 509) drank alcohol at least once a week and this proportion rose to 57% in the oldest age group. Boys and girls differed significantly in their diet, with girls choosing healthier foods. Dietary habits, in particular drinking habits, differed also significantly between education levels, assessed by the learning option of the participants. The semi-quantitative questionnaire showed that two-thirds of the adolescents had a lipid intake (mainly saturated fatty acids) which exceeded 35% of the total caloric intake. Complex carbohydrates represented less than half of the total carbohydrates intake. CONCLUSION: The study of the diet of Belgian adolescents confirmed the strong influence of tradition, in particular on the consumption of high fat content foods. The promotion of healthy diet in adolescents should consider the cultural influence, even for this young age group [less ▲]

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See detailIncinérateurs, crise dioxine et risques sanitaires pour la population belge
Bernard; Fierens; Mairesse et al

in Bulletin de la Classe des Sciences. Académie Royale de Belgique (2001), 1-6

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See detailComment j'explore ... une myopathie par biopsie musculaire
Deprez, Manuel ULg

in Revue Médicale de Liège (2001), 56(1), 49-52

Muscle biopsy is a valuable tool in the diagnosis of many neuromuscular disorders. It is an invasive investigation that will be considered after careful clinical examination, supplemented by biological ... [more ▼]

Muscle biopsy is a valuable tool in the diagnosis of many neuromuscular disorders. It is an invasive investigation that will be considered after careful clinical examination, supplemented by biological and electrophysiological studies. The biopsy procedure and the subsequent processing of specimen in the laboratory significantly influence the information provided by the microscopic examination of muscle tissue. They are reviewed in details in this article. Close collaboration between clinicians and neuropathologists in the setting of an optimized procedure will further increase the diagnostic yield of muscle biopsy. [less ▲]

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See detailLa lecture littéraire : le pour et le contre
Dumortier, Jean-Louis ULg

in Education-Formation (2001), 262

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See detailEuropean Citizenship Practice - A. Wiener
Martiniello, Marco ULg

in Nations & Nationalism (2001), 7(1), 121-122

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See detailEffect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.
Neer, R M; Arnaud, C D; Zanchetta, J R et al

in New England Journal of Medicine [=NEJM] (2001), 344(19), 1434-41

BACKGROUND: Once-daily injections of parathyroid hormone or its amino-terminal fragments increase bone formation and bone mass without causing hypercalcemia, but their effects on fractures are unknown ... [more ▼]

BACKGROUND: Once-daily injections of parathyroid hormone or its amino-terminal fragments increase bone formation and bone mass without causing hypercalcemia, but their effects on fractures are unknown. METHODS: We randomly assigned 1637 postmenopausal women with prior vertebral fractures to receive 20 or 40 microg of parathyroid hormone (1-34) or placebo, administered subcutaneously by the women daily. We obtained vertebral radiographs at base line and at the end of the study (median duration of observation, 21 months) and performed serial measurements of bone mass by dual-energy x-ray absorptiometry. RESULTS: New vertebral fractures occurred in 14 percent of the women in the placebo group and in 5 percent and 4 percent, respectively, of the women in the 20-microg and 40-microg parathyroid hormone groups; the respective relative risks of fracture in the 20-microg and 40-microg groups, as compared with the placebo group, were 0.35 and 0.31 (95 percent confidence intervals, 0.22 to 0.55 and 0.19 to 0.50). New nonvertebral fragility fractures occurred in 6 percent of the women in the placebo group and in 3 percent of those in each parathyroid hormone group (relative risk, 0.47 and 0.46, respectively [95 percent confidence intervals, 0.25 to 0.88 and 0.25 to 0.861). As compared with placebo, the 20-microg and 40-microg doses of parathyroid hormone increased bone mineral density by 9 and 13 more percentage points in the lumbar spine and by 3 and 6 more percentage points in the femoral neck; the 40-microg dose decreased bone mineral density at the shaft of the radius by 2 more percentage points. Both doses increased total-body bone mineral by 2 to 4 more percentage points than did placebo. Parathyroid hormone had only minor side effects (occasional nausea and headache). CONCLUSIONS: Treatment of postmenopausal osteoporosis with parathyroid hormone (1-34) decreases the risk of vertebral and nonvertebral fractures; increases vertebral, femoral, and total-body bone mineral density; and is well tolerated. The 40-microg dose increased bone mineral density more than the 20-microg dose but had similar effects on the risk of fracture and was more likely to have side effects. [less ▲]

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See detailFlow rate quality of new flat fan nozzles
Huyghebaert, Bruno; Debouche, Charles ULg; Mostade, Olivier

in Transactions of the ASAE (2001), 44(4), 769-773

Manufacturers of spraying nozzles have established manufacturing tolerances to guarantee the quality of their products. They control, among other things, the new nozzles’ flow rate by comparison with the ... [more ▼]

Manufacturers of spraying nozzles have established manufacturing tolerances to guarantee the quality of their products. They control, among other things, the new nozzles’ flow rate by comparison with the nominal flow rate. When the deviation exceeds a set limit, the nozzles are rejected. A survey carried out among three manufacturers made it possible to determine the manufacturing tolerances and limits that manufacturers impose upon themselves. The flow rates of 1565 new nozzles collected on the market from these manufacturers were measured on a device developed for this study. Different statistical tests assessed the performances and characteristics of the products. The quality standards announced by the manufacturers were not checked for every nozzle. On average, 20% of the new nozzles exceeded the manufacturing tolerances. The average flow rate of the nozzle sets equalled the nominal flow rate. In practice, the probability distribution of the flow rate of new nozzles should be normal. The dispersion of the new nozzle flow rates was slightly higher than the theoretical one. The quality of the products differed from one manufacturer to another. [less ▲]

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See detailc-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells.
Minet, E.; Michel, G.; Mottet, Denis ULg et al

in Experimental Cell Research (2001), 265(1), 114-24

Hypoxia is an important pathophysiological stress that occurs during blood vessel injuries and tumor growth. It is now well documented that hypoxia leads to the activation of several transcription factors ... [more ▼]

Hypoxia is an important pathophysiological stress that occurs during blood vessel injuries and tumor growth. It is now well documented that hypoxia leads to the activation of several transcription factors which participate in the adaptive response of the cells to hypoxia. Among these transcription factors, AP-1 is rapidly activated by hypoxia and triggers bFGF, VEGF, and tyrosine hydroxylase gene expression. However, the mechanisms of AP-1 activation by hypoxia are not well understood. In this report, we studied the events leading to AP-1 activation in hypoxia. We found that c-jun protein accumulates in hypoxic HepG2 cells. This overexpression is concomitant with c-jun phosphorylation and JNK activation. Moreover, we showed that AP-1 is transcriptionally active. We also observed that AP-1 transcriptional activity is inhibited by a MEKK1 dominant negative mutant. Moreover, the MEKK1 dominant negative mutant as well as deletion of the AP-1 binding sites within the c-jun promoter inhibited the c-jun promoter activation by hypoxia. All together, these results indicate that, in hypoxic HepG2 cells, AP-1 is activated through a JNK-dependent pathway and that it is involved in the regulation of the c-jun promoter, inducing a positive feedback loop on AP-1 activation via c-jun overexpression. [less ▲]

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See detailPre-and post-harvest application of antagonistic yeasts for the control of gray and blue mold: efficacy and monitoring
De Clercq, D.; Dickburt, C.; Lepoivre, Philippe ULg et al

in Phytopathology (2001), 91(6), 21

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See detailLa représentation des travailleurs à l’heure de la flexibilité : conséquences, enjeux et perspectives
Agro, Linda ULg; Dieu, Anne-Marie; Schoenaers, Frédéric ULg

in Revue de Gestion des Ressources Humaines (2001), 39

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See detailNouvelles approches thérapeutiques puor l'hypernéphrome métastasique
Sylvestre, Rose-Marie; Jerusalem, Guy ULg; Sautois, Brieuc ULg et al

in Médecine et Hygiène (2001), 59

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See detailComparison between the GIRBAS Scale and the Acoustic and Aerodynamic Measures Provided by EVA for the Assessment of Dysphonia following Unilateral Vocal Fold Paralysis.
Morsomme, Dominique ULg; Jamart, Jacques; Wery, Carine et al

in Folia Phoniatrica et Logopaedica (2001), 53(6), 317-25

The aim of this study is to establish relevant objective parameters for evaluating dysphonia following unilateral vocal fold paralysis. To do so, the study compares objective and perceptual voice measures ... [more ▼]

The aim of this study is to establish relevant objective parameters for evaluating dysphonia following unilateral vocal fold paralysis. To do so, the study compares objective and perceptual voice measures. The objective measures were obtained using a voice analysis software (Evaluation Vocale Assistee), whereas the perceptual measures were established with the GIRBAS Scale (grade, instability, roughness, breathiness, asthenia, and strain). All measurements were performed on 40 voice samples: 28 dysphonic subjects with unilateral laryngeal paralysis, and 12 control subjects. The intra- and inter-judge agreements were fairly good, at least for control subjects. The six GIRBAS measures obtained from the pathological voices were higher than those from the control voices (p < 0.001) and the correlation between both groups was good. Grade, breathiness and asthenia correlated with the objective parameters that express the aperiodicity of the phonatory signal (p < 0.01), namely, the coefficient of variability of the fundamental frequency, the coefficient of variability of intensity, and jitter. Our findings suggest that the perceptual reality of laryngeal paralysis-induced dysphonia depends more on grade, breathiness and asthenia than it does on roughness or instability. [less ▲]

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See detailL'indexation de l'allocation pour l'aide d'une tierce personne : deux lectures distinctes pour un même problème.
Michiels, Olivier ULg

in Revue Générale des Assurances et des Responsabilités (2001)

L'article s'attache à cerner la jurisprudence divergente de la Cour de cassation et de la Cour d'arbitrage - devenue constitutionnelle - relative à l'indexation de l'allocation pour l'aide d'une tierce ... [more ▼]

L'article s'attache à cerner la jurisprudence divergente de la Cour de cassation et de la Cour d'arbitrage - devenue constitutionnelle - relative à l'indexation de l'allocation pour l'aide d'une tierce personne. [less ▲]

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See detailA comparison of the efficacy and tolerability of meloxicam and diclofenac in the treatment of patients with osteoarthritis of the lumbar spine.
Valat, J P; Accardo, S; REGINSTER, Jean-Yves ULg et al

in Inflammation Research (2001), 50(Suppl 1), 30-4

OBJECTIVE: The aim of this study was to evaluate the efficacy and tolerability of meloxicam compared with diclofenac in patients with osteoarthritis of the lumbar spine. SUBJECTS: 229 patients with ... [more ▼]

OBJECTIVE: The aim of this study was to evaluate the efficacy and tolerability of meloxicam compared with diclofenac in patients with osteoarthritis of the lumbar spine. SUBJECTS: 229 patients with radiologically confirmed osteoarthritis of the lumbar spine. TREATMENT AND METHODS: Once-daily meloxicam 7.5 mg tablet or diclofenac 100 mg slow release tablet. Efficacy and tolerability parameters were assessed at baseline and after 3, 7 and 14 days of treatment. RESULTS: The two drugs had equal short-term efficacy, with pain on motion of lumbar spine significantly (p<0.05) decreased at Day 3. Secondary efficacy variables were also significantly improved at Days 3, 7 and 14. There were no statistically significant differences between the two drugs, although the global tolerability of meloxicam was significantly better than for diclofenac, as assessed by the investigators (p = 0.0072) and the patients (p = 0.049). CONCLUSIONS: Meloxicam and diclofenac were equivalent in relieving the acute pain associated with osteoarthritis of the lumbar spine. However, meloxicam was much better tolerated. [less ▲]

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See detailCell cycle activation of hematopoietic progenitor cells increases very late antigen-5-mediated adhesion to fibronectin.
Giet, Olivier ULg; Huygen, Sandra; Beguin, Yves ULg et al

in Experimental hematology (2001), 29(4), 515-24

Recent studies suggested that trafficking of hematopoietic progenitor cells is related to cell cycle status. We studied whether adhesion of progenitor cells to extracellular matrix proteins was modulated ... [more ▼]

Recent studies suggested that trafficking of hematopoietic progenitor cells is related to cell cycle status. We studied whether adhesion of progenitor cells to extracellular matrix proteins was modulated by cell cycle transit.Mobilized peripheral blood CD34+ cells were stimulated ex vivo for 48 hours with stem cell factor, flt-3 ligand, and thrombopoietin and fractionated by adhesion to fibronectin or vascular cell adhesion molecule-1 (VCAM-1). Adherent and nonadherent cells were assayed for cell cycle status, long-term culture-initiating cell frequency, and integrin function. Binding to fibronectin, but not to VCAM-1, displayed a cell cycle selectivity as the adherent fraction to fibronectin was enriched in cycling CD34+ cells and in cycling long-term culture-initiating cells compared to the nonadherent fraction. Combined cell cycle and phenotypic analysis showed that the expression of VLA-5 was upregulated during S/G2+M but that of VLA-4 remained constant. The selective binding of cycling CD34+ cells to fibronectin was reverted by anti-VLA-5 but not by anti-VLA-4 blocking antibodies. Also, cycling CD34+ cells preferentially adhered to the VLA-5 binding domain but not to the VLA-4 binding domain of fibronectin. Adhesion of cycling CD34+ cells to fibronectin was a reversible process modulated by cell cycle progression, because adherent cells could exit the cell cycle and return to a nonadhesive state within an additional 48-hour culture period.The results indicate that the enhanced binding capacity of cycling progenitor cells to fibronectin is mediated by VLA-5. [less ▲]

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See detailIntraconzole versus amphotericin B plus nystatin in the prophylaxis of fungal infections in neutropenic cancer patients
Boogaerts, Marc; Maertens, Johan; van Hoof, Achiel et al

in Journal of Antimicrobial Chemotherapy (2001), 48

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See detailImidazolopyrazinones as potential antioxydants
Devillers, Ingrid; Dive, Georges ULg; De Tollenaere, Catherine et al

in Bioorganic & Medicinal Chemistry Letters (2001), 11(17), 2305-2309

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See detailPurification and characterization of a 43.5 kDa keratinolytic metalloprotease from Microsporum canis.
Brouta, F.; Descamps, F.; Fett, Thomas ULg et al

in Medical Mycology (2001), 39(3), 269-275

A keratinolytic protease secreted by a feline clinical isolate of Microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by ... [more ▼]

A keratinolytic protease secreted by a feline clinical isolate of Microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by affinity chromatography on bacitracin-agarose and by hydrophobic chromatography on octyl-agarose. The enzyme had an apparent molecular mass of 43.5 kDa and the pI was 7.7. It had a significant activity against keratin azure, elastin-Congo red and denatured type I collagen (azocoll). Using the latter substrate, the optimum pH was around 8 and the apparent optimum temperature around 50 degrees C. The protease was strongly inhibited by 1,10-phenanthroline, phosphoramidon and EDTA. The first 13 N-terminal amino acid sequence showed a 61% homology with that of the extracellular metalloprotease of Aspergillus fumigatus and with the neutral protease I of A. oryzae, confirming that this 43.5 kDa keratinase is a metalloprotease. This keratinolytic metalloprotease could be a virulence-related factor involved in pathophysiological mechanisms of M. canis dermatophytosis. [less ▲]

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See detailSpermine induces precocious development of the spleen in Wistar rat
Peulen, Olivier ULg; Jolois, Olivier ULg; Galopin, Catherine et al

in Trends in Comparative Biochemistry and Physiology (2001), 8

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See detailThe Secret History of Belgian Surrealism
Delville, Michel ULg

in Samizdat (2001)

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See detailLa fin de la vie en médecine intensive
Ferdinande, P.; Berré, J.; Colardyn, F. et al

in Réanimation (2001), 10

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See detailDonnées récentes sur la pathogenèse de l'infection à Microsporum canis chez les carnivores domestiques
Brouta, F.; Descamps, F.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (2001), 145

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See detailEquilibrium basal-plane magnetization of superconductive YNi(2)B(2)C: The influence of nonlocal electrodynamics
Thompson, J. R.; Silhanek, Alejandro ULg; Civale, L. et al

in Physical Review. B : Condensed Matter (2001), 64(2),

For a single crystal of YNi(2)B(2)C superconductor, the equilibrium magnetization M in the square basal Plane has been studied experimentally as a function of temperature and magnetic field. While the ... [more ▼]

For a single crystal of YNi(2)B(2)C superconductor, the equilibrium magnetization M in the square basal Plane has been studied experimentally as a function of temperature and magnetic field. While the magnetization M(H) deviates from conventional London predictions, a recent extension of London theory (to include effects of nonlocal electrodynamics) describes the experiments accurately. The resulting superconductive parameters are well behaved. These results are compared with corresponding findings for the case with M perpendicular to the basal plane. [less ▲]

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See detailReticulocyte transferrin receptor (TfR) expression and contribution to soluble TfR levels.
R'Zik, Samir ULg; Loo, Martine; Beguin, Yves ULg

in Haematologica (2001), 86(3), 244-51

BACKGROUND AND OBJECTIVES: Transferrin receptor (TfR) expression in erythroid cells is regulated by a number of factors, including iron status and erythropoietin (Epo) stimulation. However, the impact of ... [more ▼]

BACKGROUND AND OBJECTIVES: Transferrin receptor (TfR) expression in erythroid cells is regulated by a number of factors, including iron status and erythropoietin (Epo) stimulation. However, the impact of these factors on reticulocyte TfR expression in vivo has never been studied. A soluble form of TfR (sTfR) is present in serum in proportion to the mass of cellular TfR. Although sTfR shedding by reticulocytes and erythroblasts has been demonstrated in vitro, the contribution of reticulocyte TfR to serum sTfR has never been evaluated in vivo. DESIGN AND METHODS: We measured directly the total number of reticulocyte TfR in normal rats of different age and iron status, as well as in animals experiencing various conditions and treatments aimed at altering erythropoietic activity and iron status, including rHuEpo therapy, hemolytic anemia, phlebotomies, hypertransfusions, thiamphenicol-induced red cell aplasia or inflammation. In addition, we examined the impact of repeated hypertransfusions with normal, reticulocyte-poor and reticulocyte-rich blood on serum sTfR levels. RESULTS: The number of TfR molecules per reticulocyte was around 50,000 in young rats but was around 100,000 in older animals. These values remained constant in most conditions and in particular were not influenced by iron supplementation or iron overload. However, functional iron deficiency as well as rHuEpo therapy resulted in increased reticulocyte TfR expression. In addition, TfR numbers in reticulocytes were elevated in the early phase of recovery after acute hemolysis or red cell aplasia but normalized soon after. Hypertransfusion experiments clearly demonstrated that reticulocytes can contribute substantially to sTfR levels in vivo. INTERPRETATION AND CONCLUSIONS: TfR numbers are regulated in vivo by the same factors as in vitro, in particular iron deficiency and erythropoietin stimulation. Circulating reticulocytes contribute significantly to serum sTfR levels. [less ▲]

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See detailSecondary fabrics revealed by remanence anisotropy: methodological study and examples from plutonic rocks
Trindade, Ricardo I.F.; Bouchez, Jean-Luc; Bolle, Olivier ULg et al

in Geophysical Journal International (2001), 147(2), 310-318

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See detailUnraveling Oligodendrocyte Origin and Function by Cell-Specific Transgenesis
Belachew, Shibeshih ULg; Yuan, Xiaoqing; Gallo, Vittorio

in Developmental Neuroscience (2001), 23(4-5), 287-98

Besides the role of mature oligodendrocytes in myelin synthesis during the development of the central nervous system (CNS), the oligodendrocyte lineage also encompasses the largest pool of postnatal ... [more ▼]

Besides the role of mature oligodendrocytes in myelin synthesis during the development of the central nervous system (CNS), the oligodendrocyte lineage also encompasses the largest pool of postnatal proliferating progenitors whose behavior in vivo remains broadly elusive in health and disease. We describe here transgenic models that allow us to track the functions and origins of such cells by using proteolipid protein and 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) gene promoters to direct oligodendroglial expression of different reporters, in particular the green fluorescent protein (GFP). We emphasize that the CNP-GFP mouse, which targets the entire oligodendroglial lineage from embryonic life to adulthood, provides an outstanding tool to study the in vivo properties of oligodendrocyte progenitor cells in normal and damaged CNS. [less ▲]

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See detailModified hormonal balance in rooting-recalcitrant rac mutant tobacco shoots
Faivre-Rampant, Odile; Kevers, Claire ULg; Dommes, Jacques ULg et al

in Plant Biosystems (2001), 135(1), 85-93

The rooting-recalcitrant rac tobacco mutant has been multiplied in vitro via outgrowth of axillary buds in parallel to the DS wild-type. The mutant shoots grew at a lower rate and did not root whatever ... [more ▼]

The rooting-recalcitrant rac tobacco mutant has been multiplied in vitro via outgrowth of axillary buds in parallel to the DS wild-type. The mutant shoots grew at a lower rate and did not root whatever the treatments, whereas the wild-type shoots rooted spontaneously during the culture cycle without auxin treatment. The mutant and wild-type shoots showed similar peroxidase variations along the culture cycle (21 days) but with higher levels of activity for the rac mutant: minimum peroxidase activity occurrey at day 14 in whole shoots of both tobacco genotypes, but already at day 7 in the basal parts of the stems (where roots appear) of the wild-type tobacco, while it was delayed in the mutant. Free and conjugated auxin and polyamine levels were also determined in whole shoots and basal parts of the stems. The rac mutant was characterised by higher auxin and polyamine contents. A peak of auxins and polyamines appeared at day 14 in the whole shoots whatever the tobacco genotype. This peak was delayed in the basal parts of the rac stems compared to the wild-type ones. The mutant shoots contained higher levels of benzyladenine and isopentenyladenosine at the end of the culture cycle, whereas zeatin riboside was more abundant in wild-type shoots. In response to increasing concentrations of indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA), only the wild-type shoots responded by an increase in growth rate followed by inhibition at high concentrations. The rac shoot responses were very low or nonexistent. Peroxidase activity was also measured in E basal parts of tobacco stems grown in the presence of IBA. Results suggest growth inhibition related to auxin accumulation, possibly combined with elevated putrescine content. Second, rooting induction seems to take place in both tobacco genotypes; however, the process of root formation is blocked in the mutant. The lack of initiation and expression phases of rooting in relation to auxin content in the mutant is discussed. [less ▲]

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See detailThe organotypic culture of HPV-transformed keratinocytes: an effective in vitro model for the development of new immunotherapeutic approaches for mucosal (pre)neoplastic lesions.
Delvenne, Philippe ULg; Hubert, Pascale ULg; Jacobs, Nathalie ULg et al

in Vaccine (2001), 19(17-19), 2557-64

The purpose of this study is to develop a reliable in vitro human model to test new immunotherapeutic approaches for squamous cell carcinoma that develop on mucosal surfaces. The organotypic (raft ... [more ▼]

The purpose of this study is to develop a reliable in vitro human model to test new immunotherapeutic approaches for squamous cell carcinoma that develop on mucosal surfaces. The organotypic (raft) culture permits cells to proliferate and differentiate at an air-liquid interface on a dermal equivalent support. Normal keratinocytes stratify and fully differentiate in a manner similar to the normal squamous epithelial tissues, while human papillomavirus-immortalized and established squamous carcinoma cell lines exhibit dysplastic morphologies similar to (pre)neoplastic lesions seen in vivo. We have demonstrated the ability of these organotypic cultures to be manipulated by altering the epithelial stratification with cytokines (interferon-gamma and tumor necrosis factor-alpha) and by integrating activated lymphocytes or dendritic cells into the in vitro formed epithelial sheet. This model may provide a useful tool to investigate the factors contributing to the presence and function of immunocompetent cells within a neoplastic epithelium that develops on a mucosal surface. [less ▲]

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See detailDoes ovarian surgery for endometriomas impair the ovarian response to gonadotropin?
Donnez, Jacques; Wyns, Christine; NISOLLE, Michelle ULg

in Fertility and Sterility (2001), 76(4), 662-5

Objective: To evaluate the ovarian response to stimulation conducted for IVF treatment in women who have undergone conservative surgery for endometriomas. Design: Retrospective study with prospective ... [more ▼]

Objective: To evaluate the ovarian response to stimulation conducted for IVF treatment in women who have undergone conservative surgery for endometriomas. Design: Retrospective study with prospective selection of participants and controls. Setting: University infertility clinic. Patient(s): A series of 374 women who underwent in vitro fertilization (IVF). The study group consisted of 85 patients with ovarian endometriomas who had undergone laparoscopic surgery in an attempt to become pregnant, but had failed within a year of surgery. The control group consisted of 289 patients with tubal factor infertility. Intervention(s): IVF-embryo transfer procedures. Main Outcome Measure(s): Stimulation parameters, fertilization, implantation, and pregnancy rates were analyzed in both groups. Result(s): There was no significant difference between the two groups in stimulation parameters or IVF outcome. Conclusion(s): A total of 820 cycles were analyzed. A similar IVF-ET outcome was observed in patients with endometriosis after ablation of endometriomas compared to women with tubal factors. In conclusion, endometrioma surgery by internal wall vaporization does not impair IVF outcome. The clinical pregnancy rate was respectively 37.4% and 34.6% in the endometriosis group and the control group. [less ▲]

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See detailSpécificités de la fonction cardiorespiratoire de l'âne (Equus asinus)
Delvaux, Véronique ULg; Kirschvink, Nathalie; Amory, Hélène ULg et al

in Pratique Vétérinaire Equine (2001), 33(129), 21-28

A group of 22 donkeys underwent a serres of non-invasive cardiorespiratory tests in order to establish the reference standards for this species and compare the results with those for horses. For ... [more ▼]

A group of 22 donkeys underwent a serres of non-invasive cardiorespiratory tests in order to establish the reference standards for this species and compare the results with those for horses. For particular tests (haematology, measurement of arterial blond gases, electrocardiogram with phonocardiogram and thoracic radiographs, cardias echography), no major differences were found. However, the mechanical ventilation parameters differed from those for horses and moere similar to Chose for food-producing animais (carde): a higher resistance, a lower compliance and a higher maximum pleural pressure variation moere found. The "respiratory strategy" adopted by certain donkeys is different from that of horses: there are two to three phases of inspiration with a nil airflow between each phase. Expiration is the same as for horses. The conformation of the pharynx and larynx is slightly different to that of horses making it more difficult to pass an endoscope through this area. The lower respiratory tract is sensitive and it is necessary to apply a local anaesthetic (xylocaine) for this examination. The différential leukocyte count from tracheal lavage includes a number of epithelial cells, and a higher percentage of eosinophils and neutrophile for donkeys compared to horses. These similarities and différences between donkeys and horses should be taken into account when performing ancillary tests [less ▲]

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See detailAnticyclonic eddies in the deep eastern Black Sea in summer-autumn 1999 (satellite and ship-borne observations
Ginzburg, Anna I.; Zatsepin, Andrey; Kostianoy, Andrey G. et al

in Earth Observation and Remote Sensing (2001), 5

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See detailSome properties of generalized age-distribution equations in fluid dynamics
Beckers, Jean-Marie ULg; Delhez, Eric ULg; Deleersnijder, Eric

in SIAM Journal on Applied Mathematics (2001), 61(5), 1526-1544

The concept of age in fluid dynamics is analyzed in the case of a tracer advection-diffusion equation. From the general solution in a uniform velocity field, it is shown that unexpected symmetry ... [more ▼]

The concept of age in fluid dynamics is analyzed in the case of a tracer advection-diffusion equation. From the general solution in a uniform velocity field, it is shown that unexpected symmetry properties arise for the age field. In particular, for a point release, the age field is isotropic, regardless of the direction of the ow and the value of the diffusion coefficient. The analysis is then extended to situations with time-varying currents, where the symmetry can be broken under some circumstances. Finally, we show a method by which a time-dependent problem can be used to assess a stationary concentration distribution function, providing details about the propagation of younger and older material at a given location. [less ▲]

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See detailCompte rendu de Frédéric Barbier, Histoire du livre
Durand, Pascal ULg

in Bulletin des Bibliothèques de France (2001), 46/4

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See detailLes techniques d'empreinte en implantologie
Van Heusden, Alain ULg

in Revue Belge de Médecine Dentaire = Belgisch Tijdschrift voor Tandheelkunde (2001), 56(3), 189-203

The implant-borne prostheses have become an integral part of the oral rehabilitation procedures. The aim of this article is to describe the most current impression techniques for oral implant prosthetics ... [more ▼]

The implant-borne prostheses have become an integral part of the oral rehabilitation procedures. The aim of this article is to describe the most current impression techniques for oral implant prosthetics used at the University of Liege, Belgium. Impression protocols adapted to various prosthetic procedures are described step-by-step through several clinical cases. Emphasis is put on the means necessary for achieving a precise adaptation and a passive fit of the final prosthetic suprastructure. [less ▲]

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See detailL'exigence de motivation des décisions ordonnant un repérage ou une écoute téléphonique
Jacobs, Ann ULg

in Revue de Droit Pénal et de Criminologie (2001)

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See detailRadiative lifetime measurements and transition probabilities of astrophysical interest in Er III
Biémont, Emile ULg; Garnir, Henri-Pierre ULg; Bastin, Thierry ULg et al

in Monthly Notices of the Royal Astronomical Society (2001), 321

Radiative lifetimes of seven excited states of Er III have been measured using time-resolved laser-induced fluorescence following two-photon excitation. Relativistic Hartree-Fock calculations taking core ... [more ▼]

Radiative lifetimes of seven excited states of Er III have been measured using time-resolved laser-induced fluorescence following two-photon excitation. Relativistic Hartree-Fock calculations taking core-polarization effects into account are found to be in excellent agreement with the experimental results. A large set of new calculated transition probabilities is presented for many transitions of astrophysical interest. These results will be useful for investigating the composition of chemically peculiar stars. [less ▲]

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See detailOral vitamin C attenuates acute ischaemia-reperfusion injury in skeletal muscle.
Kearns, S. R.; Moneley, D.; Murray, P. et al

in Journal of Bone & Joint Surgery, British Volume (2001), 83(8), 1202-6

Ischaemia-reperfusion injury (IRI) is caused by endothelial and subendothelial damage by neutrophil-derived oxidants. Vitamin C is an antioxidant which attenuates endothelial injury after IRI. Our aim was ... [more ▼]

Ischaemia-reperfusion injury (IRI) is caused by endothelial and subendothelial damage by neutrophil-derived oxidants. Vitamin C is an antioxidant which attenuates endothelial injury after IRI. Our aim was to evaluate the effect of oral vitamin C in the prevention of IRI in skeletal muscle. We used a model of cross-clamping (3 hours) and reperfusion (1 hour) of the cremaster muscle in rats. Muscle function was assessed electrophysiologically by electrical field stimulation. Infiltration by neutrophils was determined by the activity of tissue myeloperoxidase (MPO) and tissue oedema by the wet-to-dry ratio. Neutrophil respiratory burst activity was measured in control animals and groups pretreated with vitamin C. IRI significantly decreased muscle function and increased muscle neutrophil MPO activity and muscle oedema. Pretreatment with vitamin C preserved muscle function and reduced tissue oedema and neutrophil infiltration. Neutrophil respiratory burst activity was reduced in the group treated with vitamin C compared with the control group. We conclude that pretreatment with oral vitamin C protects against acute muscle IRI, possibly by attenuating neutrophil respiratory burst activity. [less ▲]

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See detailOn the origin and systematics of the northern African wood mouse (Apodemus sylvaticus) populations: a comparative study of mtDNA restriction patterns
Libois, Roland ULg; Michaux, Johan ULg; Ramalhinho, M. G. et al

in Canadian Journal of Zoology (2001), 79(8), 1503-1511

Conflicting hypotheses have been formulated regarding the origin of wood mouse (Apodemus sylvaticus) populations in northern Africa. In this study, the mtDNA restriction patterns of mice (n = 28 ... [more ▼]

Conflicting hypotheses have been formulated regarding the origin of wood mouse (Apodemus sylvaticus) populations in northern Africa. In this study, the mtDNA restriction patterns of mice (n = 28) collected in Tunisia and Morocco are compared with those of representatives from southern Europe (n = 102). The neighbour-joining tree confirms the existence of the three lineages previously found in the Mediterranean area: western, Tyrrhenian-Balkan, and Sicilian. The western group is isolated from the two others, with bootstrap values of 89 and 95%. Northern African patterns are included in the western group. Their variability is low, the same pattern being shared by five Tunisian and all Moroccan animals (n = 18), caught either in the north of the country (Cap Spartel) or in the south (Marrakech). This implies that northern African wood mouse populations have a southwestern European origin and that their presence in the region is probably recent, which corresponds to both paleontological data and the hypothesis of anthropogenic introduction. [less ▲]

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See detailThiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies.
Mollard, C.; Moali, C.; Papamicael, C. et al

in Journal of Biological Chemistry (2001), 276(48), 45015-23

Resistance to beta-lactam antibiotics mediated by metallo-beta-lactamases is an increasingly worrying clinical problem. Candidate inhibitors include mercaptocarboxylic acids, and we report studies of a ... [more ▼]

Resistance to beta-lactam antibiotics mediated by metallo-beta-lactamases is an increasingly worrying clinical problem. Candidate inhibitors include mercaptocarboxylic acids, and we report studies of a simple such compound, thiomandelic acid. A series of 35 analogues were synthesized and examined as metallo-beta-lactamase inhibitors. The K(i) values (Bacillus cereus enzyme) are 0.09 microm for R-thiomandelic acid and 1.28 microm for the S-isomer. Structure-activity relationships show that the thiol is essential for activity and the carboxylate increases potency; the affinity is greatest when these groups are close together. Thioesters of thiomandelic acid are substrates for the enzyme, liberating thiomandelic acid, suggesting a starting point for the design of "pro-drugs." Importantly, thiomandelic acid is a broad spectrum inhibitor of metallo-beta-lactamases, with a submicromolar K(i) value for all nine enzymes tested, except the Aeromonas hydrophila enzyme; such a wide spectrum of activity is unprecedented. The binding of thiomandelic acid to the B. cereus enzyme was studied by NMR; the results are consistent with the idea that the inhibitor thiol binds to both zinc ions, while its carboxylate binds to Arg(91). Amide chemical shift perturbations for residues 30-40 (the beta(3)-beta(4) loop) suggest that this small inhibitor induces a movement of this loop of the kind seen for other larger inhibitors. [less ▲]

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See detailPoly(e-caprolactone) layered silicate nanocomposites: effect of clay surface modifiers on the melt intercalation process
Pantoustier, Nadège; Alexandre, Michaël ULg; Degée, Philippe et al

in e-Polymers (2001), (9), 1-9

Nanocomposites based on biodegradable poly(e-caprolactone) (PCL) and layered silicates (montmorillonite) modified by various alkylammonium cations were prepared by melt intercalation. Depending on whether ... [more ▼]

Nanocomposites based on biodegradable poly(e-caprolactone) (PCL) and layered silicates (montmorillonite) modified by various alkylammonium cations were prepared by melt intercalation. Depending on whether the ammonium cations contain non-functional alkyl chains or chains terminated by carboxylic acid or hydroxyl functions, microcomposites or nanocomposites were recovered as shown by X-ray diffraction and transmission electron microscopy. Mechanical and thermal properties were examined by tensile testing and thermogravimetric analysis. The layered silicate PCL nanocomposites exhibited some improvement of the mechanical properties (higher Young's modulus) and increased thermal stability as well as enhanced flame retardant characteristics as result of a charring effect. This communication aims at reporting that the formation of PCL-based nanocomposites strictly depends on the nature of the ammonium cation and its functionality, but also on the selected synthetic route, i.e. melt intercalation vs. in situ intercalative polymerization. Typically, protonated w-aminododecanoic acid exchanged montmorillonite allowed to intercalate e-caprolactone monomer and yielded nanocomposites upon in situ polymerization, whereas they exclusively formed microcomposites when blended with preformed PCL chains. In other words, it is shown that the formation of polymer layered silicate nanocomposites is not straightforward and cannot be predicted since it strongly depends on parameters such as ammonium cation type and functionality together with the production procedure, i.e., melt intercalation, solvent evaporation or in situ polymerization [less ▲]

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See detailA world monograph of the lichen genus Gyalectidium (Gomphillaceae)
Ferraro, Lidia Itati; Lücking, Robert; Sérusiaux, Emmanuël ULg

in Botanical Journal of the Linnean Society (2001), 137

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See detailExploring Consumer Evaluations of e-Services: A Portal Site
Van Riel, Allard ULg; Liljander, Veronica

in International Journal of Service Industry Management (2001), 12(4), 359-377

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See detailSens de la cohérence, colère et trouble obsessionnel-compulsif
Lambert, Stéphanie; Etienne, Anne-Marie ULg; Fontaine, Ovide ULg

in Revue Francophone de Clinique Comportementale et Cognitive (2001), 6(4), 5-16

This study assesses the relationship between the Sense of Coherence (SoC) of Antonovsky, anger and the obsessive-compulsive disorder. The sample is composed of 42 subjects divided in two groups, 21 ... [more ▼]

This study assesses the relationship between the Sense of Coherence (SoC) of Antonovsky, anger and the obsessive-compulsive disorder. The sample is composed of 42 subjects divided in two groups, 21 subjects suffering of obsessive-compulsive disorder and 21 subjects matched controls. They completed a demographic questionnaire, the list of obsessions and compulsions of Goodman & al.(1989), translation Mollard, Cottraux & Bouvard (1989), the Visual Analogues Scales, the Orientation Life Questionnaire of Antonovsky (1987), the State-Trait Anger Expression Inventory of Spielberger (STAXI), the State-Trait Anxiety Inventory of Spielberger (STAI), and the Beck Depression Inventory (BDI). The results show higher scores of anxiety and depression in obsessive-compulsive patients than in controls subjects. According to the results obtained with the Anger Inventory, the obsessive-compulsive subjects show higher scores of state-anger, of anger-expression and higher scores of anger-control. The results of the Sense of Coherence scale reveal a lower SoC in TOC group than in control group. The SoC is also negatively associated with depression and anxiety in both groups. The SoC is negatively associated with the control of anger in the TOC group and with the suppression of anger in the control group. The theorical and clinical implications of these results are discussed. [less ▲]

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See detailL'avenir de l'enseignement
de Landsheere, Gilbert ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (5-6), 59-78

La Wallonie est, de longue tradition, pays d'éducation. Cela lui a valu la place de choix qu'elle occupe tant dans le domaine de l'économie que dans celui de la culture. Nous traversons actuellement une ... [more ▼]

La Wallonie est, de longue tradition, pays d'éducation. Cela lui a valu la place de choix qu'elle occupe tant dans le domaine de l'économie que dans celui de la culture. Nous traversons actuellement une période difficile. La restructuration politique de notre pays a absorbé beaucoup d'énergie et le long processus qui y a conduit n'a pas permis de prendre à temps, en particulier pour l'éducation, des décisions scientifiques et administratives urgentes. Le retard pris ainsi est alarmant et, s'il s'accentuait encore, il pourrait entraîner des décrochages et des pertes d'une gravité extrême. La chance veut que les connaissances nécessaires à l'élévation généralisée de la qualité de l'éducation et de sa productivité arrivent à maturité. On dispose ainsi d'éléments solides pour fonder les décisions et mettre en oeuvre une politique éducative qui nous permette d'entrer avec assurance dans le XXI ème siècle. Toute décision en matière d'éducation est indissociable de jugements de valeur et des réalités économiques et sociales. Ne fût-ce que par réalisme, les options humanistes et démocratiques s'imposent, car seuls ces deux idéaux sont garants de progrès et donnent l'espoir d'éviter des mouvements sociaux qui pourraient se solder par un désastre. En revanche, si la raison et la justice triomphent, la civilisation nouvelle qui émerge pourrait dépasser en qualité et en noblesse tout ce que l'humanité a connu jusqu'à présent. [less ▲]

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See detailImplication de la neurohypophyse dans le stress psychique
Scantamburlo, Gabrielle ULg; Ansseau, Marc ULg; Legros, Jean-Jacques ULg

in Encéphale (L') (2001), 27(3, May-Jun), 245-59

Effects of different psychological stimuli on oxytocin (OT) and vasopressin (AVP) secretion are reviewed in animals and in humans. The secretion of neuropituitary hormones is also discussed in various ... [more ▼]

Effects of different psychological stimuli on oxytocin (OT) and vasopressin (AVP) secretion are reviewed in animals and in humans. The secretion of neuropituitary hormones is also discussed in various psychiatric diseases such an anorexia nervosa, bipolar disorder, schizophrenia and obsessive-compulsive disorder. AVP and OT are secreted into the hypophyseal portal circulation by neurons which project from the paraventricular nucleus to the external zone of the median eminence. AVP and OT-containing neurons in the suprachiasmatic and paraventricular nuclei project to limbic areas, including the hippocampus, the subiculum, the ventral nucleus of the amygdala and the nucleus of the diagonal band. Specific AVP receptors which are pharmacologically different from the pressor and antidiuretic AVP receptors have been found in the anterior pituitary. OT receptors have been identified in a variety of forebrain sites. The neurohypophyseal secretion is regulated by the cholinergic muscarinic, histaminergic and beta-adrenergic systems. Stress alters the secretion of one or more of the hypothalamic factors which interact at the pituitary to increase the secretion of ACTH. AVP and OT have been shown to modulate the effect of Corticotropin-Releasing Factor (CRF) on ACTH secretion and appear to play a key role in mediating the ACTH response to stress. Although AVP is a relatively weak secretagogue for ACTH, it markedly potentiates the activity of CRF both in vitro and in vivo. The role of OT is more complex. In vitro, OT stimulates ACTH release at high doses whereas in human it inhibits ACTH secretion at low doses. The type of stressor appear to determine the relative importance of these secretatogues in ACTH response. Several recent studies indicate that psychological stressors display a similar degree of variety of secretagogue release patterns as was found earlier for physical stressors. A bewildering array of technique produces a bewildering array of conclusions. In rats, OT may be an important secretagogue during a novel stimulus, whereas the role for AVP is less clear. Indeed two studies out of ten suggest a stimulating role for AVP. In response to frustration and submission, OT and AVP are secreted. Regarding social isolation, results are difficult to interpret and the role of AVP could be species-dependent. In contrast plasma OT levels do not change. After restraint, ACTH release is primarily mediated by the active increase of OT and AVP does not appear to play a role. When restraint is associated with moderate levels of physical components and during immobilisation, all two secretagogs are involved in the ACTH response. With fear, ACTH response appears to be driven by OT. In humans, one study indicates that high emotionality women increase plasma OT in response to uncontrollable noise. Various neuroendocrine dysregulations have been observed in psychiatric disease. Either an increase or a decrease of the hypothalamic-pituitary-adrenal (HPA) function have been described in several illnesses. Effects of OT appear to be reciprocal to the effects of AVP. OT has been called the "amnestic" neuropeptide due to its capacity to attenuate memory consolidation and retrieval. AVP exhibits a central activating action on mood, memory and selective attention. Underweight patients with anorexia nervosa have abnormally high levels of centrally directed AVP and reduced OT levels. These modifications could enhance the retention of cognitive distortions of aversive consequences of eating. Patients with bipolar disorder show a biphasic secretion of AVP. Depressive episodes are associated with decreased vasopressinergic activity whereas manic episodes involve an increased release. AVP might be responsible for an increased catecholamine activity. In addition, lithium could act as an antagonist to AVP. In schizophrenic patients, studies using the apomorphine stimulation suggest increased oxytoninergic and decreased vasopressinergic functions. These findings are consistent with the beneficial role of AVP on schizophrenic symptoms noted in several trials. The increased OT could be responsible for "positive" symptomatology such as delusions and hallucinations. Obsessive compulsive disorder (OCD) includes a range of cognitive and behavioral disturbances that could be influenced by OT. In animals, several studies have emphasized the role of AVP in promoting repetitive grooming behaviors and maintaining conditioned response to aversive stimuli. In OCD patients, one study have reported that AVP/OT ratio was negatively correlated with symptom severity. However, an independent report found similar AVP concentrations in OC patients without a personal or family history of tic disorder and in normal subjects. Whether these modifications are only a consequence of the central disturbances or whether those peptides could participate in the pathogenesis of these affections remains to be elucidated. [less ▲]

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See detailProductivity Overshadows Temperature In Determining Soil And Ecosystem Respiration Across European Forests
Janssens, Ia.; Lankreijer, H.; Matteucci, G. et al

in Global Change Biology (2001), 7(3),

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See detailLe pilotage des systèmes d'enseignement
de Landsheere, Gilbert ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (5-6), 115-120

Un peu moins de trois ans après le congrès 'La Wallonie au futur. Le défi de l'éducation' (Namur, octobre 1991), Gilbert de Landsheere reprend la parole lors de l'introduction d'une conférence-consensus ... [more ▼]

Un peu moins de trois ans après le congrès 'La Wallonie au futur. Le défi de l'éducation' (Namur, octobre 1991), Gilbert de Landsheere reprend la parole lors de l'introduction d'une conférence-consensus (Namur, mars 1994) sur le thème 'Où en est et où va le système éducatif en Wallonie? Comment le savoir ?'. Il y est plus inquiet et en colère que jamais... et il le fait savoir ! Il poursuit la réflexion qu'il avait livrée dans deux des textes que nous publions également dans ces Cahiers ('L'avenir de l'enseignement' et 'Propositions relatives à l'enseignement'). Il expose aussi la substance de l'ouvrage qu'il fera publié chez De Boeck la même année. [less ▲]

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See detailConsumer Evaluations of Brand Extensions: Differences between Goods and Services
Van Riel, Allard ULg; Lemmink, Jos; Ouwersloot, Hans

in Journal of Service Research (2001), 3(3), 220-231

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See detailValue of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: results of the European Organization for Research and Treatment of Cancer 58881 randomized phase III trial.
Millot, F; Suciu, S; Philippe, N et al

in Journal of Clinical Oncology (2001), 19

PURPOSE: The European Organization for Research and Treatment of Cancer 58881 study was designed to test in a prospective multicentric randomized trial the value of high-dose (HD) intravenous (IV ... [more ▼]

PURPOSE: The European Organization for Research and Treatment of Cancer 58881 study was designed to test in a prospective multicentric randomized trial the value of high-dose (HD) intravenous (IV) cytarabine (Ara-C) added to HD IV methotrexate (MTX) to reduce the incidence of CNS and systemic relapses in children with increased-risk acute lymphoblastic leukemia (ALL) or stage III and IV lymphoblastic lymphoma treated with a Berlin-Frankfurt-Munster (BFM)-based regimen. PATIENTS AND METHODS: After completion of induction-consolidation phase, children with increased-risk (risk factor > 0.8 or T-lineage) ALL or stage III and IV lymphoblastic lymphoma were randomized to receive four courses of HD MTX (5 g/m(2) over 24 hours every 2 weeks) and four intrathecal administrations of MTX (Arm A) or the same treatment schedule with additional HD IV Ara-C (1 g/m(2) in bolus injection 12 and 24 hours after the start of each MTX infusion) (Arm B). RESULTS: Between January 1990 and January 1996, 653 patients with ALL (593 patients) or lymphoblastic lymphoma (60 patients) were randomized: 323 were assigned to Arm A (without Ara-C) and 330 to Arm B (with Ara-C). A total of 190 events (177 relapses and 13 deaths without relapse) were reported, and the median follow up was 6.5 years (range, 2 to 10 years). The incidence rates of CNS relapse were similar in both arms whether isolated (5.6% and 3.3%, respectively) or combined (5.3% and 4.6%, respectively). The estimated 6-year disease-free survival (DFS) rate was similar (log-rank P =.67) in the two treatment groups: 70.4% (SE = 2.6%) in Arm A and 71.0% (SE = 2.5%) in Arm B. The 6-year DFS rate was similar for ALL and LL patients: 70.2% (SE = 1.9%) versus 76.3% (SE = 5.6%). CONCLUSION: Prevention of CNS relapse was satisfactorily achieved with HD IV MTX and intrathecal injections of MTX in children with increased-risk ALL or stage III and IV lymphoblastic lymphoma treated with our BFM-based treatment protocol in which cranial irradiation was omitted. Disappointingly, with the dose schedule used in this protocol, HD Ara-C added to HD MTX, although well tolerated, failed to further decrease the incidence of CNS relapse or to improve the overall DFS. [less ▲]

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See detailAnaesthesia for laparoscopic surgery
Kaba, Abdourahmane ULg; Joris, Jean ULg

in Current Anaesthesia and Critical Care (2001), 12

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See detailBelgian normative data of the temperament and character inventory
Hansenne, Michel ULg; Le Bon, O.; Gauthier, Audrey ULg et al

in European Journal of Psychological Assessment (2001), 17(1), 56-62

The Temperament and Character Inventory (TCI) is a 226-item self-questionnaire developed to assess the seven dimensions of personality described by Cloninger and his colleagues. Normative data from 322 ... [more ▼]

The Temperament and Character Inventory (TCI) is a 226-item self-questionnaire developed to assess the seven dimensions of personality described by Cloninger and his colleagues. Normative data from 322 representative French-speaking subjects from Belgium are presented and the psychometric properties are discussed. Mean scores of temperament dimensions were appreciably different from those published by Cloninger. In our sample, novelty seeking and self-transcendence scores were lower and harm avoidance scores were higher compared to US norms. The other dimensions were almost identical. The factorial analysis showed that the hypothesized factor structure of temperament and character dimensions was almost confirmed. The present study also confirmed that the TCI scales were weakly related among themselves. The relationships were consistent with those reported by previous reports. Gender differences were also found for different dimensions. [less ▲]

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See detailDetermination of the scattering coefficient of random rough diffusing surfaces for room acoustics applications
Embrechts, Jean-Jacques ULg; Archambeau, Dominique; Stan, Guy-Bart

in Acta Acustica United with Acustica (2001), 87

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See detailCorrect regimen of fluoride and calcium reduces the risk of vertebral fractures in postmenopausal osteoporosis
Reginster, Jean-Yves ULg; Rovati, L; Setnikar, I

in Osteoporosis International (2001), 12

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See detailApplication of the accelerated shelf life testing method (ASLT) to study the survival rates of freeze-dried Lactococcus starter cultures
Achour, M.; Mtimet, N.; Cornelius, C. et al

in Journal of Chemical Technology & Biotechnology (2001), 74

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See detailProcollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis.
Fernandes, R. J.; Hirohata, S.; Engle, J. M. et al

in Journal of Biological Chemistry (2001), 276(34), 31502-9

The amino and carboxyl propeptides of procollagens I and II are removed by specific enzymes as a prerequisite for fibril assembly. Null mutations in procollagen I N-propeptidase (ADAMTS-2) cause ... [more ▼]

The amino and carboxyl propeptides of procollagens I and II are removed by specific enzymes as a prerequisite for fibril assembly. Null mutations in procollagen I N-propeptidase (ADAMTS-2) cause dermatosparaxis in cattle and the Ehlers-Danlos syndrome (dermatosparactic type) in humans by preventing proteolytic excision of the N-propeptide of procollagen I. We have found that procollagen II is processed normally in dermatosparactic nasal cartilage, suggesting the existence of another N-propeptidase(s). We investigated such a role for ADAMTS-3 in Swarm rat chondrosarcoma RCS-LTC cells, which fail to process the procollagen II N-propeptide. Stable transfection of RCS-LTC cells with bovine ADAMTS-2 or human ADAMTS-3 partially rescued the processing defect, suggesting that ADAMTS-3 has procollagen II N-propeptidase activity. Human skin and skin fibroblasts showed 30-fold higher mRNA levels of ADAMTS-2 than ADAMTS-3, whereas ADAMTS-3 mRNA was 5-fold higher than ADAMTS-2 mRNA in human cartilage. We propose that both ADAMTS-2 and ADAMTS-3 process procollagen II, but ADAMTS-3 is physiologically more relevant, given its preferred expression in cartilage. The findings provide an explanation for the sparing of cartilage in dermatosparaxis and, perhaps, for the relative sparing of some procollagen I-containing tissues. [less ▲]

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See detailLes etats preleucemiques: d'un modele experimental murin aux syndromes myelodysplasiques humains
Defresne, Marie-Paule ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2001), 156(1-2), 99-104105-6

Using a model of experimental leukemia in mice, we have demonstrated that tumor development depends upon interactions between preleukemic cells and their microenvironment whose functions are altered ... [more ▼]

Using a model of experimental leukemia in mice, we have demonstrated that tumor development depends upon interactions between preleukemic cells and their microenvironment whose functions are altered. Cytokine injections inhibit tumor development by inducing a functional restoration of this environment. Human myelodysplastic syndromes (MDS) are marrow pathologies considered as preleukemic stages. As in murine leukemias, it is possible that marrow environment could play a key role in their evolution. We currently establish a model of human hematopoiesis in NOD/SCID mice grafted with human bone fragments. We hope that this model would allow to analyse the role of the marrow stromal cells in MDS and to establish treatments restoring their functions. [less ▲]

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See detailVies et Miracles de Domitien Deuxième partie
George, Philippe ULg

in Analecta Bollandiana : Revue Critique d’Hagiographie = A Journal of Critical Hagiography (2001), CXIX

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See detailLe martin-pêcheur (Alcedo atthis) va-t-il bientôt manquer de sites de nidification ?
Libois, Roland ULg

in Aves (2001), 38(4), 161-178

In south-west Belgium, the breeding of the kingfisher was monitored for more than 10 years. During this period, 158 banks were regularly surveyed. Alterations or potential threats were identified: natural ... [more ▼]

In south-west Belgium, the breeding of the kingfisher was monitored for more than 10 years. During this period, 158 banks were regularly surveyed. Alterations or potential threats were identified: natural erosion, cattle trampling, disturbance from kayak-riders or anglers and, last but not least, consolidation works. Only 56 banks (35.4 %) can de considered as "safe". However, since the recent (2001) legal restrictions about the navigation on small rivers, 12 more banks are now safe too. Cattle trampling appears as the main threat (55 sites). However, the enforcement of the law regulating the fences along the rivers could easily solve the problem. Nineteen banks were completely destroyed for different purposes: navigation, road retaining walls or simply anti-erosive measures. Most of these works were undertaken along the river Meuse, the best nidification habitat of the area. (11 photos) [less ▲]

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See detailGérer l'hétérogénéité des élèves : Méthodes de regroupement des élèves dans l'enseignement obligatoire
Monseur, Christian ULg; Demeuse, Marc ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 25-52

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See detailEditorial: Les Systèmes de production agricole et la protection des cultures à la croisée des chemins
Lepoivre, Philippe ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2001), 5(4), 195-199

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See detailLes surcoûts de l’étalement urbain en Wallonie
Halleux, Jean-Marie ULg

in Etudes Foncières (2001), (94), 18-21

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See detailCore-shell-corona micelles with a responsive shell
Gohy, Jean-François; Willet, Nicolas ULg; Varshney, Sunil et al

in Angewandte Chemie (International ed. in English) (2001), 40(17), 3214-3216

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See detailHuman Fdc Express Prpc in Vivo and in Vitro
Thielen, Caroline ULg; Antoine, Nadine ULg; Mélot, France ULg et al

in Developmental Immunology (2001), 8(3-4), 259-66

Prion diseases are fatal neurodegenerative disorders caused by accumulation of abnormal prion protein (protease-resistant prion, PrPres). PrPres accumulation is also detected in lymphoid organs after ... [more ▼]

Prion diseases are fatal neurodegenerative disorders caused by accumulation of abnormal prion protein (protease-resistant prion, PrPres). PrPres accumulation is also detected in lymphoid organs after peripheral infection. Several studies suggest that follicular dendritic cells (FDC) could be the site of PrPres retention and amplification. Here we show that human follicular dendritic cells can express normal cellular prion protein (PrPc) both in situ and in vitro. When tonsillar cryosections were treated with anti-PrP antibody, the label was found on some very delicate cell extensions inside the lymphoid follicles, especially in the germinal centres. These extensions react with DRC1 antibody, used frequently to label FDC. Other structures labelled with anti-PrP antibody were the keratinocytes. To confirm the ability of FDC to synthesise PrPc, we isolated FDC by a non-enzymatic procedure and cultured them. By cytochemistry and flow cytometry it was clearly shown that FDC do produce PrPc. [less ▲]

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See detailThe interior-to-edge breakpoint distance as a guideline for nature conservation policy.
Bogaert, Jan ULg; Salvador-Van Eysenrode, D; Impens, I

in Environmental Management (2001), 27(4), 493-500

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See detailRegime alimentaire du Grand-Duc du désert, Bubo ascalaphus, dans la réserve naturelle de Mergueb (M'Sila, Algérie)
Biche, Mohamed; Sellami, Medhi; Libois, Roland ULg et al

in Alauda (2001), 69(4), 554-557

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical ... [more ▼]

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical basis (82 %) as well as in term of biomass (96 %) was Meriones shawi trouessarti (Gerbillidae). Other preys included Jaculus orientalis (Dipodidae), and two insectivores: Crocidura russula and Hemiechinus aethiopicus. Among the avifauna, only the Spanish sparrow (Passer hispaniolensis) was a significant part of the Eagle owl dietn especially in spring. Arthropods were represented by Scarabeidae in spring and Scorpionidae in summer but they played a minor role in the food of the Eagle owl. The originality of this diet lies in the absence of Brown hare (Lepus capensis) and the presence of only one specimen of the desert hedgehog. Although its food spectrum was very narrow in this site, the Eagle owl can be regarded as opportunistic as it concentrated on the most available prey: Meriones shawi. [less ▲]

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See detailSerum transferrin receptor concentration indicates increased erythropoiesis in Kenyan children with asymptomatic malaria.
Verhoef, H.; West, C. E.; Ndeto, P. et al

in American Journal of Clinical Nutrition (2001), 74(6), 767-75

BACKGROUND: Serum transferrin receptor concentrations indicate both erythropoietic activity and the deficit of functional iron in the erythron. In contrast with serum ferritin concentrations, serum ... [more ▼]

BACKGROUND: Serum transferrin receptor concentrations indicate both erythropoietic activity and the deficit of functional iron in the erythron. In contrast with serum ferritin concentrations, serum transferrin receptor concentrations are not or are only marginally influenced by the inflammatory response to infection. OBJECTIVE: We assessed iron status and examined the relation between serum transferrin receptor concentrations and malaria in children aged 2-36 mo who were asymptomatic for malaria. DESIGN: This was a community-based cluster survey (n = 318). RESULTS: Prevalences of malaria, anemia (hemoglobin concentration <110 g/L), iron deficiency (serum ferritin concentration <12 microg/L), and iron deficiency anemia were 18%, 69%, 53%, and 46%, respectively. Malaria was associated with lower mean hemoglobin concentrations (92.7 compared with 104.1 g/L; P = 0.0001) and higher geometric mean serum concentrations of transferrin receptor (11.4 compared with 7.8 mg/L; P = 0.005), ferritin (21.6 compared with 11.9 microg/L; P = 0.05), and C-reactive protein (12.5 compared with 6.8 mg/L; P = 0.004). There was no evidence for an association between serum concentrations of C-reactive protein and transferrin receptor. Children with malaria had higher serum transferrin receptor concentrations than expected for the degree of anemia, even after adjustment for inflammation indicated by serum C-reactive protein concentration quartiles (P = 0.02). CONCLUSIONS: Our findings are consistent with the notion that malaria-induced hemolysis is accompanied by increased erythropoiesis. Serum transferrin receptor concentration is not useful for detecting iron deficiency in individuals with malaria. Individuals with high concentrations of serum C-reactive protein or similar acute phase reactants should be excluded from analysis if serum ferritin concentrations <12 microg/L are to be used to measure iron deficiency in malaria-endemic areas. [less ▲]

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See detailQuoi de neuf en littératie ? : Regard sur trente ans d'évaluation de la lecture
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 71-95

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