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See detailImmunohistochemical analysis of estrogen and progesterone receptors in endometrium and peritoneal endometriosis: a new quantitative method.
NISOLLE, Michelle ULg; Casanas-Roux, Françoise; Wyns, Christine et al

in Fertility and Sterility (1994), 62(4), 751-9

Objective: To evaluate estrogen receptors (ER) and progesterone receptors (PR) content in glandular and stromal cells of eutopic and ectopic endometrium. DESIGN: A recently advanced stereographic computer ... [more ▼]

Objective: To evaluate estrogen receptors (ER) and progesterone receptors (PR) content in glandular and stromal cells of eutopic and ectopic endometrium. DESIGN: A recently advanced stereographic computer technology was applied for the investigation of steroid receptors. SETTING: University hospital department of gynecology. PATIENTS: Biopsies of endometrium and typical peritoneal endometriotic lesions were taken from 19 infertile patients with laparoscopically proved endometriosis. Endometrial biopsies were also taken from 15 patients without endometriosis. All of them were untreated. RESULTS: In normal endometrium, the highest concentrations of ER and PR occurred in the epithelial and stromal cells during the late proliferative phase of the menstrual cycle. Estrogen receptor and PR content declined throughout the secretory phase. Progesterone receptor content was found not to be significantly decreased in the stroma during the early secretory phase and quite high in the late secretory phase. In peritoneal endometriotic lesions, the highest concentrations of ER and PR were found during the late proliferative phase. When compared with normal endometrium, a lower ER content ans a similar PR content were observed, and the cyclic changes in peritoneal endometriosis lesions were also similar. CONCLUSION: A new computerized technology for the evaluation of ER and PR in eutopic and ectopic endometrium. Although the ER content was found to be lower in endometriotic tissue when compared with endometrium, the cyclic pattern was similar in both eutopic and ectopic endometrium. Progesterone receptor content was similar in both tissues, except during the late secretory phase in ectopic glandular epithelium in which a high persistent PR content was observed. [less ▲]

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See detailHuman RelB (I-Rel) functions as a kappa B site-dependent transactivating member of the family of Rel-related proteins.
Bours, Vincent ULg; Azarenko, V.; Dejardin, Emmanuel ULg et al

in Oncogene (1994), 9(6), 1699-702

RelB belongs to the family of Rel-related proteins, dimers of which determine NF-kappa B activity. The murine RelB protein has been reported to be a dimerizing partner in kappa B-binding complexes which ... [more ▼]

RelB belongs to the family of Rel-related proteins, dimers of which determine NF-kappa B activity. The murine RelB protein has been reported to be a dimerizing partner in kappa B-binding complexes which are capable of transactivation. On the other hand, the I-Rel protein, the presumed human homolog of RelB, was proposed to be an inhibitor whose presence in dimeric complexes interfered with their kappa B binding and therefore interfered also with transactivation. We demonstrate that human RelB (I-Rel) forms with p50 and p52 (p50B) kappa B-binding heterodimeric complexes which potently transactivate kappa B-dependent constructs in transfection studies. It is concluded that human RelB (I-Rel) and murine RelB can both function as transactivators and that no significant species-specific differences exist. [less ▲]

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See detailL'hémorragie pulmonaire induite par l'exercise chez le cheval: une énigme de la médecine équine ?
Art, Tatiana ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1994), 138

This review analyses the epidemiology, etiology, anatomo- and physiopathology, diagnose and prevention of the syndrome of exercise pulmonary hemorrhage in horses

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See detailL'enseignement du français instrumental à l'université: quelles possibilités?
Vanden Berghe, Kristine ULg; Sanctobin, Véronique; Slootmaekers, An et al

in Rencontres (1994), 5

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See detailModulatory Effect of Neuropeptide Y on Acetylcholine-Induced Oedema and Vasoconstriction in Isolated Perfused Lungs of Rabbit
Delaunois, Annie ULg; Gustin, Pascal ULg; Dessy-Doize, C. et al

in British Journal of Pharmacology (1994), 113(3), 973-81

1. The modulatory role of neuropeptide Y (NPY) on pulmonary oedema induced by acetylcholine and capsaicin was investigated. The effects of NPY on the haemodynamic response to acetylcholine, phenylephrine ... [more ▼]

1. The modulatory role of neuropeptide Y (NPY) on pulmonary oedema induced by acetylcholine and capsaicin was investigated. The effects of NPY on the haemodynamic response to acetylcholine, phenylephrine and substance P were also investigated. 2. Isolated, ventilated, exsanguinated lungs of the rabbit were perfused with a constant flow of recirculating blood-free perfusate. The double/arterial/venous occlusion method was used to partition the total pressure gradient (delta Pt) into four components: the arterial gradient (delta Pa), the pre- and post-capillary gradients (respectively delta Pa' and delta Pv') and the venous pressure gradient (delta Pv). Endothelial permeability was evaluated by measuring the capillary filtration coefficient (Kf,c). 3. Acetylcholine (10(-8) M to 10(-4) M) and substance P (SP, 10(-10) M to 10(-6) M) induced a concentration-dependent increase in the Kf,c. Capsaicin (10(-4) M) and 5-hydroxytryptamine (5-HT) (10(-4) M) also increased this parameter. NPY (10(-8) M) completely inhibited the effects of acetylcholine and capsaicin on the Kf,c, without preventing the effects of substance P and 5-HT. 4. Acetylcholine induced concentration-dependent vasoconstriction in the precapillary segment. The effect was inhibited by NPY and aspirin, an inhibitor of cyclo-oxygenase, while ketanserin, a 5-HT2 receptor antagonist, and SR140333, a new NK1 antagonist, had no protective effect. Phenylephrine increased delta Pa at high concentration, an effect also inhibited by NPY and aspirin. Substance P had no significant haemodynamic effect. When injected together with NPY, substance P (10(-6) M) induced a significant increase in the total pressure gradient.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailDe limite en frontière : le monde à la mesure de l'homme
Bachelet, Jean-François ULg

in Revue de l'Institut de Sociologie (1994), 3-4

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See detailUne contrefaçon liégeoise exemplaire : les Œuvres du philosophe bienfaisant (1764)
Droixhe, Daniel ULg

in Bulletin de la Société Royale Le Vieux-Liège (1994), 265

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See detailEndoscopic management of ectopic pregnancy.
Donnez, Jacques; NISOLLE, Michelle ULg

in Bailliere's Clinical Obstetrics & Gynaecology (1994), 8(4), 707-2

The rationale for the conservative management of ectopic pregnancy is the preservation of reproductive potential. Removal of trophoblast through a linear incision (salpingotomy) can be easily performed by ... [more ▼]

The rationale for the conservative management of ectopic pregnancy is the preservation of reproductive potential. Removal of trophoblast through a linear incision (salpingotomy) can be easily performed by endoscopy. The injection of vasopressin into the broad ligament is required in less than 10% of cases and its routine use is not recommended because of the risk of severe side-effects. The techniques in cases of isthmic or cornual tubal pregnancy are also described. Other alternatives such as expectant management, methotrexate, RU 486 and prostaglandins have also recently been proposed. Although methotrexate therapy has been demonstrated to be effective in cases of unruptured tubal pregnancy, further studies are needed to determine whether or not this medical therapy is a safer option than laparoscopic surgery and to compare the subsequent intrauterine and recurrent ectopic pregnancy rates. Endoscopic salpingotomy is an efficacious procedure. Indeed, residual trophoblast is found in only 5% of cases after this surgical procedure. In these cases of persistent trophoblast, methotrexate is proposed as the medical approach of choice. Evaluation of the postoperative fertility after linear salpingotomy demonstrates an intrauterine pregnancy rate of 63% and a recurrent ectopic pregnancy rate of 8%. In conclusion, endoscopic management of tubal pregnancy is a safe and efficacious therapy. The contraindications are relative and depend essentially on the surgeon's experience. [less ▲]

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See detailFood Consumption in Belgium
Reginster-Haneuse, G.; Gosset, Christiane ULg

in Bibliotheca Nutritio et Dieta (1994), (51), 108-12

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See detailAnalysis of the penA gene of Pseudomonas cepacia 249.
Joris, Bernard ULg; Galleni, Moreno ULg; Frère, Jean-Marie ULg et al

in Antimicrobial Agents and Chemotherapy (1994), 38(2), 407-8

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See detailELEMENT DIFFUSION IN THE SOLAR INTERIOR
Thoul, Anne ULg; BAHCALL, J. N.; LOEB, A.

in Astrophysical Journal (1994), 421(2), 828-842

We study the diffusion of helium and other heavy elements in the solar interior by solving exactly the set of flow equations developed by Burgers for a multicomponent fluid, including the residual heat ... [more ▼]

We study the diffusion of helium and other heavy elements in the solar interior by solving exactly the set of flow equations developed by Burgers for a multicomponent fluid, including the residual heat-flow terms. No approximation is made concerning the relative concentrations, and no restriction is placed on the number of elements considered. We give improved diffusion velocities for hydrogen, helium, oxygen, and iron, in the analytic form derived previously by Bahcall & Loeb. These expressions for the diffusion velocities are simple to program in stellar evolution codes and are expected to be accurate to similar to 15%. We find that the inclusion of the residual heat flow terms leads to an increase in the hydrogen diffusion velocity. We compare our numerical results-with those obtained analytically by Bahcall & Loeb using a simplified treatment, as well as with those derived numerically by Michaud & Proffitt. We find that for conditions characteristic of the Sun, the results of Bahcall & Loeb for the hydrogen diffusion velocity are smaller than our more accurate numerical results by similar to 30%, except very near the center where the error becomes larger. The Michaud & Proffitt results differ from the numerical results derived here by less than or similar to 15%. Our complete treatment of element diffusion can be directly incorporated in a standard stellar evolution code by means of an exportable subroutine, but, for convenience, we also give simple analytical fits to our numerical results. [less ▲]

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See detailConnection and frame design for economy
Anderson, D.; Colson, A.; Jaspart, Jean-Pierre ULg

in Bouwen met Staal (1994), n°117

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See detailThe Compartmentation of Phosphorylated Thiamine Derivatives in Cultured Neuroblastoma Cells
Bettendorff, Lucien ULg

in Biochimica et Biophysica Acta (1994), 1222(1), 7-14

Thiamine transport in cultured neuroblastoma cells is mediated by a high-affinity carrier (KM = 40 nM). In contrast, the uptake of the more hydrophobic sulbutiamine (isobutyrylthiamine disulfide) is ... [more ▼]

Thiamine transport in cultured neuroblastoma cells is mediated by a high-affinity carrier (KM = 40 nM). In contrast, the uptake of the more hydrophobic sulbutiamine (isobutyrylthiamine disulfide) is unsaturable and its initial transport rate is 20-times faster than for thiamine. In the cytoplasm, sulbutiamine is rapidly hydrolyzed and reduced to free thiamine, the overall process resulting in a rapid and concentrative thiamine accumulation. Incorporation of radioactivity from [14C]thiamine or [14C]sulbutiamine into intracellular thiamine diphosphate is slow in both cases. Despite the fact that the diphosphate is probably the direct precursor for both thiamine monophosphate and triphosphate, the specific radioactivity increased much faster for the latter two compounds than for thiamine diphosphate. This suggests the existence of two pools of thiamine diphosphate, the larger one having a very slow turnover (about 17 h); a much smaller, rapidly turning over pool would be the precursor of thiamine mono- and triphosphate. The turnover time for thiamine triphosphate could be estimated to be 1-2 h. When preloading the cells with [14C]sulbutiamine was followed by a chase with the same concentration of the unlabeled compound, the specific radioactivities of thiamine and thiamine monophosphate decreased exponentially as expected, but labeling of the diphosphate continued to increase slowly. Specific radioactivity of thiamine triphosphate increased first, but after 30 min it began to slowly decrease. These results show for the first time the existence of distinct thiamine diphosphate pools in the same homogeneous cell population. They also suggest a complex compartmentation of thiamine metabolism. [less ▲]

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See detailReasoning about Infinite Computations
Vardi, Moshe Y.; Wolper, Pierre ULg

in Information & Computation (1994), 115(1), 1-37

We investigate extensions of temporal logic by connectives defined by finite automata on infinite words. We consider three different logics, corresponding to three different types of acceptance conditions ... [more ▼]

We investigate extensions of temporal logic by connectives defined by finite automata on infinite words. We consider three different logics, corresponding to three different types of acceptance conditions (finite, looping, and repeating) for the automata. It turns out, however that these logics all have the same expressive power and that their decision problems are all PSPACE-complete. We also investigate connectives defined by alternating automata and show that they do not increase the expressive power of the logic or the complexity of the decision problem. (C) 1994 Academic Press, Inc. [less ▲]

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See detailOn destabilizing implicit factors in discrete advection-diffusion equations
Beckers, Jean-Marie ULg

in Journal of Computational Physics (1994), 111(2), 260-265

In the present paper, we find necessary and sufficient stability conditions for a simple one-time step finite difference discretization of an N-dimensional advection-diffusion equation. Furthermore, it is ... [more ▼]

In the present paper, we find necessary and sufficient stability conditions for a simple one-time step finite difference discretization of an N-dimensional advection-diffusion equation. Furthermore, it is shown that when the implicit factors differ in each direction, a strange behavior occurs: By increasing one implicit factor in only one direction, a stable scheme can become unstable. It is thus suggested to use a single implicit direction (for efficient computing), or the same implicit factor in each direction. (C) 1994 Academic Press, Inc. [less ▲]

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See detailThe coupling of quark and gluon condensates in hot and dense systems
Jaminon, Martine ULg; Van den Bossche, Bruno

in Nuclear Physics A (1994), 567

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See detailRole des somatomedines/insulin-like growth factors dans la croissance ponderale foetale.
Renaville, Robert ULg; Falaki, M.; Burny, A. et al

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(3),

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See detailControl of drug-resistant epilepsy after head injury with intravenous nimodipine.
HANS, Pol ULg; Triffaux, M.; BONHOMME, Vincent ULg et al

in Acta Anaesthesiologica Belgica (1994), 45(4), 175-8

The present report describes a young child who developed generalized epileptic seizures in the course of severe head injury. The start of epileptic seizures was associated with the occurrence of acute ... [more ▼]

The present report describes a young child who developed generalized epileptic seizures in the course of severe head injury. The start of epileptic seizures was associated with the occurrence of acute hyponatremia and hypoosmolality due to excessive Desmopressine administration. The seizures resistant to conventional therapy resolved completely with intravenous nimodipine infusion. [less ▲]

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See detailHooliganisme: approches descriptives et explicatives, avec une attention particulière aux faits observés en Belgique
Comeron, Manuel ULg

in Revue Internationale de Criminologie et de Police Technique (1994), 2

Etude du phénomène de violence dans les stades de football en Belgique avec une approche empirique des supporters et hooligans du Standard de Liège couplée avec une synthèse théorique des travaux anglo ... [more ▼]

Etude du phénomène de violence dans les stades de football en Belgique avec une approche empirique des supporters et hooligans du Standard de Liège couplée avec une synthèse théorique des travaux anglo-saxons. [less ▲]

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See detailFluid transfer in anorthosites and related rocks from Rogaland (Southwest Norway): Evidence from stable isotopes
Wilmart, Edith; Pineau, Françoise; Réjou-Michel, A. et al

in Earth & Planetary Science Letters (1994), 125

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See detailConditional watershed segmentation for grain boundary reconstruction
Pirard, Eric ULg; Delanaye, Annick ULg

in Acta Stereologica (1994), 14(1), 23-28

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See detailFirst-principles calculations of dielectric and effective charge tensors in Barium Titanate
Ghosez, Philippe ULg; Gonze, X.; Michenaud, J. P.

in Ferroelectrics (1994), 153

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See detailBiostatistical studies of Western European allogamous populations of the Epipactis helleborine (L.) Crantz species group (Orchidaceae)
Tyteca, D.; Dufrêne, Marc ULg

in Systematic Botany (1994), 19(3), 424-442

[No abstract available]

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See detailThe 4s-4p Transitions in Neutral Phosphorus
Biémont, Emile ULg; Martin, F.; Quinet, Pascal ULg et al

in Astronomy and Astrophysics (1994), 283

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See detailThe phytoplankton community of the river Meuse, Belgium: seasonal dynamics (year 1992) and the possible incidence of zooplankton grazing
Gosselain, Véronique ULg; Descy, Jean-Pierre; Everbecq, Etienne ULg

in Hydrobiologia (1994), 289

Qualitative and quantitative aspects of the phytoplankton of the river Meuse were studied during 1992 at a point 537 km from the source. The phytoplankton was dominated by diatoms and green algae. The ... [more ▼]

Qualitative and quantitative aspects of the phytoplankton of the river Meuse were studied during 1992 at a point 537 km from the source. The phytoplankton was dominated by diatoms and green algae. The factors regulating the phytoplankton groxth were clearly physical variables : discharge, temperature and irradiance. [less ▲]

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See detailR. Sacré, « Les Negro Spirituals et les Gospel Songs »
Pirenne, Christophe ULg

in Cahiers de Clio (1994), 119

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See detailCharacterization of a single prolactin (PRL) receptor in tilapia (Oreochromis niloticus) which binds both PRLI and PRLII
Auperin, B.; Rentier-Delrue, Françoise ULg; Martial, Joseph ULg et al

in Journal of Molecular Endocrinology (1994), 13(3), 241-51

In tilapia, there are two forms of prolactin (PRL) whose effects on sodium and chloride movements differ and depend on the living environment of the fish. To see whether different receptors or the same ... [more ▼]

In tilapia, there are two forms of prolactin (PRL) whose effects on sodium and chloride movements differ and depend on the living environment of the fish. To see whether different receptors or the same receptor mediates these different effects, we have characterized the specific binding of both forms of tilapia (ti)PRL in two osmoregulatory organs, the gill and kidney. Two recombinant tiPRLs were used for this analysis. The recombinant hormones had the same properties as the native hormones in a tilapia gill radioreceptor assay. Specific binding to gill and kidney membranes was increased by optimizing the quality of the tissue preparations (physiological state of fish, membrane preparation) and the incubation conditions (pH, salt concentrations, temperature, time). Under these optimized conditions, we detected only one class of high affinity PRL receptor in gill and kidney. Its binding affinity was higher for tiPRLI than for tiPRLII in both gill and kidney (for tiPRLI the respective affinity values were 2.9 and 2.3 x 10(10) per M, for tiPRLII they were 1.9 and 0.5 x 10(10) per M). In competition studies, tiPRLI was more potent, followed by tiPRLII and ovine (o)PRL. tiGH and oGH did not significantly displace either tiPRL. The receptor we have characterized thus recognizes quite specifically both tiPRLs. [less ▲]

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See detailBrucellose enzootique à Brucella suis biotype 2 chez le sanglier (sus scrofa) en Belgique
Godfroid, J.; Michel, P.; Uytterhaegen, L. et al

in Annales de Médecine Vétérinaire (1994), 138

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See detailApprendre, ou se mettre en projet ? Réflexions au départ d'une expérience de pédagogie du projet en classe du secondaire
Jadoulle, Jean-Louis ULg

in Histoire et Enseignement : Bulletin (1994), 44e année(n°1), 5-17

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See detailLa régression linéaire pondérée : principes et application
Palm, Rodolphe ULg

in Notes de Statistique et d'Informatique (1994), 4

This note briefly describes the prinicples of weighted linear regression and gives two completely worked out examples from the real world.

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See detailCell localization and redistribution of the 67 kD laminin receptor and alpha 6 beta 1 integrin subunits in response to laminin stimulation: an immunogold electron microscopy study.
Romanov, V.; Sobel, M. E.; pinto da Silva, P. et al

in Cell Adhesion and Communication (1994), 2(3), 201-9

The 67 kDa laminin receptor (67LR), one of several cell surface laminin-binding proteins, is involved in the interactions between cancer cells and laminin during tumor invasion and metastasis. A 37 kDa ... [more ▼]

The 67 kDa laminin receptor (67LR), one of several cell surface laminin-binding proteins, is involved in the interactions between cancer cells and laminin during tumor invasion and metastasis. A 37 kDa polypeptide (37LRP), previously identified as the 67LR precursor, is abundantly present in the cytoplasm and has been implicated in polysome formation. To better understand the cellular localization of the 67LR and its precursor, transmission electron microscopic studies of human melanoma A2058 cells were carried out using immunogold labeling and a variety of antibodies: (a) affinity purified antibodies directed against 37LRP cDNA-derived synthetic peptides; (b) anti-67LR monoclonal antibodies raised against intact human small cell lung carcinoma cells; and (c) monoclonal antibodies against the subunits of the integrin laminin receptor, alpha 6 beta 1. Double-labeling immunocyto-chemistry revealed that anti-67LR monoclonal antibodies as well as anti-37 LRP antibodies recognized antigens that were localized in the cytoplasm in electron dense structures. As expected, cell membrane labeling was also observed. Surprisingly, alpha 6 and beta 1 integrin subunits were detected in the same cytoplasmic structures positive for the 67LR and the 37LRP. After addition of soluble laminin to A2058 cells in suspension, the number of labeled cytoplasmic structures increased especially in the vicinity of the plasma membrane, and were exported onto the cell surface. Neither fibronectin nor BSA induced such an effect. The data demonstrate that the 67 LR and the 37 LRP antibodies detect colocalized antigens that are in cytoplasmic structures with alpha 6 beta 1 integrin.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailEFFECTS OF ELECTROKINETIC CHARACTERISTICS ON THE FORMATION OF A PROTEIN MICROCRYSTALLINE CELLULOSE COMPLEX
Paquot, Michel ULg; GODIN, F.; Dumont de chassart, Q.

in Lebensmittel-Wissenschaft & -Technologie = Food Science & Technology (1994), 27(1), 11-15

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See detailLa pompe musculo-veineuse de la personne âgée
Petermans, Jean ULg; Zicot, M.

in Journal des Maladies Vasculaires (1994), 19(2), 115-8

We study the musculo-venous pump in an elderly population, free of venous disease, by use of a digitized photoplethysmograph. We measure the venous refilling time (To) and the venous drainage (Vo) during ... [more ▼]

We study the musculo-venous pump in an elderly population, free of venous disease, by use of a digitized photoplethysmograph. We measure the venous refilling time (To) and the venous drainage (Vo) during active and passive movement. In the first part, we measure Vo and To during active and passive ankle flexions among 17 patients (34 limbs) aged 82.2 years. These variables are compared to the results of the same measurements obtained among 15 young adults aged 45.1 years (30 limbs). We find that To and Vo are significantly lower in the oldest population (To j 35.9 +/- 4.8 sec, To aged 16.1 +/- 5.2 sec, p < 0.001, Vo j 4.98 +/- 1.1%, Vo ag 2.97 +/- 1%, p < 0.001). In the second part of this work, a passive massage of the calf is substituted to the ankle flexions. This technique is applied to 19 elderly people aged 80.4 years (37 limbs) compared to 6 young adults aged 24 years (12 limbs). In these conditions the comparison is no more in favour of the younger group (To j 37 +/- 7.5 sec, To ag 30.6 +/- 4.1 sec, Vo j 4.03 +/- 1.5%, Vo ag 3.8 +/- 0.06%). The values measured in the elderly group are in the range of normal values. We conclude that senescence does not alter the venous system itself. The present work confirms the influence of extravascular factors as muscles, understanding and coordination of the motions, articular flexibility, on the performance of the musculo venous pomp. As far as possible, the muscular and articular activity has to be encouraged in elderly people in order to reduce the venous stasis. [less ▲]

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See detailLa régression : un problème statistique complexe à partir d'une idée simple
Palm, Rodolphe ULg

in Biométrie-Praximétrie (1994), 34(2), 109-123

Comme beaucoup de domaines de la statistique, la régression a connu d'importants développements au cours de ces vingt-cinq dernières années et l'objectif de l'article est de présenter, de façon sommaire ... [more ▼]

Comme beaucoup de domaines de la statistique, la régression a connu d'importants développements au cours de ces vingt-cinq dernières années et l'objectif de l'article est de présenter, de façon sommaire, les développements relatifs à quelques aspects particuliers de la régression linéaire, même si certains éléments peuvent être facilement étendus ou adpatés au cas de la régression non linéaire. Nous examinerons tout d'abord le problème de la validation des résultats d'une régression, en considérant successivement les critères globaux de mesure de la qualité de la régression, la division des données et la validation croisée, les représentations graphiques et les mesures de l'influence. Ensuite, nous envisagerons l'établissement des équations de régression, en abordant le problème du choix des variables et en évoquant quelques alternatives à la régression classique, en relation, notamment, avec la colinéarité. Enfin, nous terminerons par quelques conclusions. [less ▲]

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See detailMuscle Fibre Type and Size, and Muscle Capillary Density in Young Double-Muscled Blue Belgian Cattle
Stavaux, D.; Art, Tatiana ULg; Mc Entee, Kathleen ULg et al

in Zentralblatt für Veterinarmedizin. Reihe A (1994), 41(3), 229-236

Bovine muscle biopsies were analysed for fiber type and capillary density by the acid ATP-ase and amylase-PAS methods respectively. Samples obtained from Belgian blue double muscled (DM) calves were ... [more ▼]

Bovine muscle biopsies were analysed for fiber type and capillary density by the acid ATP-ase and amylase-PAS methods respectively. Samples obtained from Belgian blue double muscled (DM) calves were compared for their fibre type, size and vascularization with samples from Friesian (F) calves. The animals were sampled both at 2 and 7 months of age. Changes in histochemical composition occurring with ageing, independently of the breed, and differences related to the muscle sampled by comparing biopsies obtained from the longissimus dorsi (LD) and gluteobiceps (GB) muscles in animals of both breed were also investigated. Independently of age and muscle, fibre type I percentage and area were significantly higher in F than in DM muscles. Type IIa area was significantly larger in F than in DM, while fibre type IIb percentage and area were higher in DM. The number of capillaries/mm2 was significantly higher in F than in DM. Fibre type IIa and IIb percentage as well as the diameter of the three fibre types was significantly higher in the oldest animals. Finally, independently of age and breed, fibre type I and IIb percentages were significantly higher in LD but lower in GB. The results mainly demonstrated that Belgian blue DM muscles present a higher proportion of IIb fibres and a lower capillary supply than F muscles. [less ▲]

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See detailCrystallization and X-ray diffraction study of the Streptomyces K15 penicillin-binding DD-transpeptidase.
Englebert, S.; Charlier, Paulette ULg; Fonze, E. et al

in Journal of Molecular Biology (1994), 241(2), 295-7

The 262 amino acid residue long DD-transpeptidase/penicillin-binding protein of Streptomyces K15 has been crystallized at room temperature by using the hanging drop vapour diffusion technique. The ... [more ▼]

The 262 amino acid residue long DD-transpeptidase/penicillin-binding protein of Streptomyces K15 has been crystallized at room temperature by using the hanging drop vapour diffusion technique. The crystals belong to the orthorhombic space group P2(1)2(1)2(1), with unit cell parameters a = 46.4 A, b = 54.1 A and c = 108.3 A. They contain one protein molecule per asymmetric unit and diffract to about 1.9 A. X-ray data have been collected to 2.0 A from a native crystal. The previously published amino acid sequence of the protein has been corrected at positions 71, 72, 113, 114 and 156. [less ▲]

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See detailEnantioselective synthesis of 6-[fluorine-18]-fluoro-L-dopa from no-carrier-added fluorine-18-fluoride.
Lemaire, Christian ULg; Damhaut, Philippe; Plenevaux, Alain ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1994), 35(12), 1996-2002

METHODS: A trimethylammonium veratraldehyde triflate was synthesized and used as a precursor for the asymmetric synthesis of 6-[18F]fluoro-L-dopa. RESULTS: Its nucleophilic fluorination with 18F-fluoride ... [more ▼]

METHODS: A trimethylammonium veratraldehyde triflate was synthesized and used as a precursor for the asymmetric synthesis of 6-[18F]fluoro-L-dopa. RESULTS: Its nucleophilic fluorination with 18F-fluoride produced by the 18O(p,n)18F nuclear reaction on enriched 18O-water led to the corresponding no-carrier-added [18F]fluoroveratraldehyde (45 +/- 5% EOB). Diiodosilane was used to prepare the corresponding [18F]fluorobenzyl iodide (36.5 +/- 5.3% EOB). Akylation of (S)-1-tert-boc-2-tert-butyl-3-methyl-4-imidazolidinone with this electrophilic agent, hydrolysis and purification by preparative high-pressure liquid chromatography made 6-[18F]fluoro-L-dopa ready for human injection, in a 23% +/- 6% decay-corrected radiochemical yield. The enantiomeric purity and the specific activity were above 96% and 1 Ci/mumole respectively. CONCLUSION: Through this procedure, starting from 250 mCi of 18F-fluoride, multimillicurie amounts (32 +/- 8.5 mCi) of no-carrier-added 6-[18F]fluoro-L-dopa are now available at the end of synthesis (90 min) with a good radiochemical purity (more than 98%). [less ▲]

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See detailEvidence that two tilapia (Oreochromis niloticus) prolactins have different osmoregulatory functions during adaptation to a hyperosmotic environment
Auperin, B.; Rentier-Delrue, Françoise ULg; Martial, Joseph ULg et al

in Journal of Molecular Endocrinology (1994), 12(1), 13-24

Two forms of prolactin (tiPRLI and tiPRLII), with only 69% sequence identity, have been previously described in the cichlid fish tilapia (Oreochromis species). In the present study we have attempted to ... [more ▼]

Two forms of prolactin (tiPRLI and tiPRLII), with only 69% sequence identity, have been previously described in the cichlid fish tilapia (Oreochromis species). In the present study we have attempted to investigate the biological activity of these two prolactin forms during adaptation to a hyperosmotic environment. For this purpose, we have developed two highly sensitive (sensitivity: 0.05 ng/ml) and specific (cross-reactivity < 0.04%) radioimmunoassays for tiPRLI and tiPRLII, using recombinant hormones. When fish were directly transferred from fresh to brackish water, the measured levels of plasma tiPRLI and tiPRLII dropped abruptly until 12 h after transfer. Thereafter, plasma tiPRLII remained stable (around 0.5 ng/ml) until the end of the experiment, whereas plasma tiPRLI continued to decrease to undetectable levels. These different patterns of change are reflected in the calculated ratio of plasma tiPRLII to tiPRLI, which increased from 2-3 in fresh water-adapted fish to over 10 in fish which had spent 3 days or more in brackish water. The pituitary contents of tiPRLI and tiPRLII varied in a qualitatively similar fashion after transfer to brackish water. The tiPRLI content dropped continuously after 12 h, reaching one-twelfth of its initial level after 2 weeks. The pituitary tiPRLII content, on the other hand, did not decrease significantly until day 7, and after a 2-week exposure to brackish water it had only decreased by 50%. When injected into tilapia adapted to brackish water, both ovine prolactin and recombinant tiPRLI induced a clear dose-dependent ion-retaining effect. In contrast, the effect induced by tiPRLII treatment was markedly smaller and not dose-dependent. Northern blot analysis of tiPRL mRNAs using either a tiPRLI or a tiPRLII cDNA probe indicated the presence of two mRNAs differing in size: a 1.7 kb mRNA coding for tiPRLI and a 1.3 kb mRNA coding for tiPRLII. After transfer to brackish water, levels of the two mRNAs decreased similarly. The present study indicates that, in O. niloticus, the two forms of prolactin have different osmoregulatory roles during adaptation to brackish water. Accordingly, their synthesis are differentially regulated after transfer to a hyperosmotic environment, presumably at a post-transcriptional level. [less ▲]

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See detailAsthme et hyperréactivité bronchique non spécifique
Louis, Renaud ULg; Kayembe, J. M.; Radermecker, Maurice ULg

in Acta Clinica Belgica (1994), 49(3-4), 148-57

Bronchial hyperresponsiveness is a hallmark of asthma although it can also be present, to a lesser extent, in other diseases. The level of bronchial responsiveness depends on immuno-inflammatory processes ... [more ▼]

Bronchial hyperresponsiveness is a hallmark of asthma although it can also be present, to a lesser extent, in other diseases. The level of bronchial responsiveness depends on immuno-inflammatory processes modifying the functional status of airway smooth muscle as well as the structure of the bronchial wall. The responsiveness toward a direct constricting pharmacological agent is poorly correlated to the one toward an indirect constricting agent or a physical stimulus which cause airway obstruction through a more complex mechanism. Transversal studies show a relationship between the severity of asthma and the level of methacholine airway responsiveness. Long term treatment with corticoids can reduce the bronchial hyperresponsiveness of asthmatics. [less ▲]

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See detailLa reproduction des poissons de nos rivières.
Poncin, Pascal ULg

in Cahiers d'Ethologie (1994), 13(3), 317-342

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See detailUn formalisme unique peut-il décrire les phénomènes acoustiques et lumineux ?
Embrechts, Jean-Jacques ULg

in Bulletin d'Acoustique (1994), 16

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See detailEvaluation de la chimiorésistance de Plasmodium falciparum. Revue des tests in vitro: méthodologie, intérêts et limites
Hayette, Marie-Pierre ULg; Carme, Bernard

in Publications Médicales Africaines (1994), 129

The chloroquine-resistance of Plasmodium falciparum appeared first in Southeast Asia and South-America during the sixties. It reached further the african continent in 1977, through Kenya and Tanzania. In ... [more ▼]

The chloroquine-resistance of Plasmodium falciparum appeared first in Southeast Asia and South-America during the sixties. It reached further the african continent in 1977, through Kenya and Tanzania. In Africa, the front of the resistance spread from East to West, and now completely covers Black Africa with different degrees of resistance. Rapidly, "in vivo" and "in vitro" tests were developped to assess the sensitivity of P. falciparum strains against the different antimalarial drugs. This paper is a review of existing "in vitro" and "in vivo" tests with their interest and limits. [less ▲]

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See detailThe cognitive approach to familiar face processing in human subjects
Brédart, Serge ULg; Bruyer, R.

in Behavioural Processes (1994), 33(1-2), 213-232

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See detailBiodegradation of the polycyclic aromatic hydrocarbons phenanthrene, naphtalene and biphenyl by bacteria isolated from a contaminated soil.
Detaille, D.; Jacques, Ph.; Thonart, Philippe ULg

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1994), 102(B8),

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See detailPlace of MALT in the immune defence system.
Heinen, Ernst ULg

in Advances in Experimental Medicine and Biology (1994), 355

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See detailMétaux lourds et isotopes stables du carbone dans la matière particulaire: distribution sur le plateau continental nord-ouest européen
Dauby, Patrick ULg; Mosora, Fiorentina; Frankignoulle, Michel et al

in Bulletin de la Société Royale des Sciences de Liège (1994), 63

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See detail"Des biet ou lombardeau": La langue d'un écrivant belgoroman du début du 17e siècle
Boutier, Marie-Guy ULg; Chambon, Jean-Pierre

in Revue de Linguistique Romane (1994), 58

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See detailChiral restoration transition in scaled effective Lagrangians
Jaminon, Martine ULg; Van den Bossche, Bruno

in Zeitschrift für Physik. C, Particles and Fields (1994), 64

We make a systematic study of the chiral restoration transition in function of the two free parameters of two scaled effective NJL Lagrangians. We show that it is not possible to reproduce with the same ... [more ▼]

We make a systematic study of the chiral restoration transition in function of the two free parameters of two scaled effective NJL Lagrangians. We show that it is not possible to reproduce with the same set of parameters the temperature behaviours of the quark condensate and of the quark entropy and a critical density at least equal to the normal density of nuclear systems. [less ▲]

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See detailFear reactions of ewes to photographic images
Vandenheede, Marc ULg; Bouissou, Marie-France

in Behavioural Processes (1994), 32

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See detailEffects of immunization against somatostatin on growth performances and growth hormone - insulin-like growth factor I and insulin plasma levels in young bulls.
Renaville, Robert ULg; Sneyers, M.; Massart, Serge et al

in Zootecnica e Nutrizione Animale (1994), 20(4),

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See detailRôle de la chirurgie carotidienne dans la prévention de l'infarctus cérébral
Limet, Raymond ULg; DESIRON, Quentin ULg; DETRY, Olivier et al

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1994), 149(5-7), 299-305306-7

A significant part of transient or permanent cerebral ischemic attacks (CIA) are due to arterio-arterial emboli issued from carotid plaques. Surgery for carotid disobstruction aims to take out emboligenic ... [more ▼]

A significant part of transient or permanent cerebral ischemic attacks (CIA) are due to arterio-arterial emboli issued from carotid plaques. Surgery for carotid disobstruction aims to take out emboligenic plaques by endarterectomy (associated to angioplasty or not). The adversaries of surgical treatment sustain two main assertions: 1. carotid stenoses are not very dangerous, because the definitive thromboses they create are easily compensated by the development of collaterals, so that the risk for stroke is low. 2. this low and late risk of spontaneous carotid thrombosis is not greater than the immediate one following carotid surgery. Those objections have been encountered in randomized North American studies (Nascet [less ▲]

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See detailB.E.M.S. : Batterie d'Evaluation de la Morpho-Syntaxe : développement, évaluation, et lignes d'action
Fayasse, M.; Comblain, Annick ULg; Rondal, Jean-Adolphe ULg

in Informations pédagogiques (1994), 12

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See detailSpectrum analysis of diaphragmatic global electromyograms in cattle, with special regard to appropriate strategy for detection of fatigue.
Desmecht, Daniel ULg; Linden, Annick ULg; Close, R. P. et al

in American Journal of Veterinary Research (1994), 55

Although the respiratory tract of healthy and diseased cattle has been intensively studied during the past few years, only a few attempts to detect dysfunctions of bovine inspiratory muscles have been ... [more ▼]

Although the respiratory tract of healthy and diseased cattle has been intensively studied during the past few years, only a few attempts to detect dysfunctions of bovine inspiratory muscles have been reported. Such technique would be useful in assessing the possibility of inspiratory muscle fatigue in the context of ventilatory failure. Fatigue in skeletal muscle is associated with characteristic changes in the electromyographic power spectrum. Power spectral analysis was therefore applied to cattle diaphragmatic electromyograms (EMGdi) to precisely determine the exact influence of motion and ECG artifacts, describe its basic frequency content, and extract a spectral index capable of providing an accurate warning of fatigue. The EMGdi was recorded via intramuscularly placed fishhook electrodes in 5 healthy young bulls during resting and stimulated respiration. The EMGdi and EGC signals were analyzed by use of power spectral density analysis after band-pass filtering (20 to 1,800 Hz). The EMGdi spectrum was concentrated in the band width 20 to 530 Hz. Electrode motion artifacts were absent, and it was always possible to find an electrode pair giving ECG-free EMGdi. Of the 12 power and frequency values used to quantitate the spectrum, the most stable was the centroid frequency. It was reproducible within and between calves and was only minimally altered by changing inspiratory load.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailEvaluation de la fonction pulmonaire du cheval par la technique scintigraphique
Votion, Dominique ULg; Art, Tatiana ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1994), 138

Scintigraphy of the respiratory system, a technique used extensively in human medecine, provides a direct and non-invasive measure of both total and regional ventilation and perfusion of each lung. This ... [more ▼]

Scintigraphy of the respiratory system, a technique used extensively in human medecine, provides a direct and non-invasive measure of both total and regional ventilation and perfusion of each lung. This article remind you some nuclear notions and describes scintigraphical techniques for horses. The resuits of studies suggest that ventilation! perfusion scintigraphy provides valuable additionnai informations on regional lung function that are not obtainable from conventional investigations. The mucociliary clearance rates from the trachea can be determinated using scintigraphy and the differenttherapeutic drugs, which are claimed to increase mucokinesis, are successively presented. Methods of radiation protection in equine nuclear medecine are described [less ▲]

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See detailENANTIOSELECTIVE SYNTHESIS OF NCA (S)-L-([ALPHA-C-11]METHYL)-TRYPTOPHAN
Plenevaux, Alain ULg; Lemaire, Christian ULg; Delfiore, Guy et al

in Applied Radiation & Isotopes (1994), 45(6), 651-653

N.c.a. (S)-L-([alpha-C-11]methyl)-tryptophan was prepared by treatment at -78-degrees-C of (2S,3aR,8aS)-1,2-bis(-methoxycarbonyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2, 3-b]-indole with lithium ... [more ▼]

N.c.a. (S)-L-([alpha-C-11]methyl)-tryptophan was prepared by treatment at -78-degrees-C of (2S,3aR,8aS)-1,2-bis(-methoxycarbonyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2, 3-b]-indole with lithium diisopropylamide and [C-11]CH3I. After hydrolysis with HI and HPLC purification, the title compound was isolated with a radiochemical yield of 36% (EOB corrected) within 22 min; e.e. was shown > 97% (n = 20); specific activity was ranging between 0.8 and 1.2 Ci (30-45 GBq)/mu mol EOB. [less ▲]

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See detailLa Shoah ne fut pas un spectacle. A propos de La liste de Schindler
Delruelle, Edouard ULg

in Cahiers de Clio (1994), 117(11),

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See detailStudies of marine epiphytic algae, Calvi, Corsica. III. Variations in the populations of epiphytic Bangiophyceae
Hoffmann, Lucien; Detienne, Xavier; Goffart, Anne ULg et al

in Cryptogamie Algologie (1994), 15(1), 53-63

Variations in the populations of Bangiophyceae (Rhodophyta) epiphytic on Cladophora prolifera and Stypocaulon scoparium were monitored qualitatively and quantitatively for two years (1981/82 and 1987/88 ... [more ▼]

Variations in the populations of Bangiophyceae (Rhodophyta) epiphytic on Cladophora prolifera and Stypocaulon scoparium were monitored qualitatively and quantitatively for two years (1981/82 and 1987/88) in nine stations with constrasting water quality in the area of Calvi (Corsica). The development of Chroodactylon ornatum was temperature dependent and showed its maximum density during the summer. The development of the other Bangiophyceae (Erythrocladia irregularis, Erythrotrichia camea, Goniotrichum alsidii, G. cornu-cewi) was correlated to the water quality in that their density increased towards the sewage discharge near to the town of Calvi. A general increase in epiphytism by Bangiophyceae between 1981 and 1988 seems to indicate an increased degree of eutrophication in the bay of Calvi. [less ▲]

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See detailDynamique du carbone inorganique des eaux de surface dans l'embouchure de l'Escaut
Frankignoulle, Michel; Biondo, Renzo ULg; Bouquegneau, Jean-Marie ULg et al

in Bulletin de la Société Royale des Sciences de Liège (1994), 61

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See detailVerticalization of behavior elicited by dopaminergic mobilization is qualitatively different between C57BL/6J and DBA/2J mice
Tirelli, Ezio ULg; Witkin, J. M.

in Psychopharmacology (1994), 116(2), 191-200

Behavioral effects of dopaminergic stimulation were compared for C57BL/6J mice and DBA/2J mice. Effects of apomorphine (APO) alone and in combination with cocaine (COC) were assessed using a time-sampling ... [more ▼]

Behavioral effects of dopaminergic stimulation were compared for C57BL/6J mice and DBA/2J mice. Effects of apomorphine (APO) alone and in combination with cocaine (COC) were assessed using a time-sampling technique that classified climbing and leaning in separate categories. Climbing occurred in DBA/2J mice only at doses of APO that were 16 times higher than the smallest effective dose in C57BL/6J mice, but relative to baseline values, effects were comparable. Whereas DBA/2J mice showed dose-dependent leaning under APO, C57BL/6J mice exhibited significantly increased leaning only after the highest APO dose. When given alone, COC produced significant climbing, but not leaning or gnawing, in either strain. COC potentiated APO-induced climbing and gnawing in both strains but did not consistently change APO-induced leaning in either strain. APO alone reduced locomotor activity and attenuated COC-induced hyperkinesia. ((c) 1997 APA/PsycINFO, all rights reserved) [less ▲]

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See detailTherapy for obesity--today and tomorrow.
Scheen, André ULg; Desaive, Claude ULg; Lefebvre, Pierre ULg

in Bailliere's Clinical Endocrinology and Metabolism (1994), 8(3), 705-27

Obesity poses a serious health hazard and its treatment is often disappointing. Besides conservative methods, the place of pharmacotherapy, very-low-calorie diets, and even, in selected cases, mechanical ... [more ▼]

Obesity poses a serious health hazard and its treatment is often disappointing. Besides conservative methods, the place of pharmacotherapy, very-low-calorie diets, and even, in selected cases, mechanical means or surgery can be considered. Effective drug treatment for obesity must reduce energy intake, or increase energy expenditure, or increase energy losses in faeces. All these possibilities have potential activities but also serious limitations. Current pharmacotherapy essentially uses anorectic drugs and the other approaches, although promising, are still under investigation. Of the anorectic compounds currently available, serotoninergic agents, like dexfenfluramine and fluoxetine, appear to have the most suitable pharmacological profile. Very-low-calorie diets could help in the short-term but should be associated with other approaches to increase the rate of long-term success. They must be well-balanced as macronutrients and micronutrients are concerned, be prescribed in well-selected patients under careful medical supervision, and not be followed longer than a few weeks. Surgery can provide palliation for severe obesity when all medical approaches have failed. It may consist in decreasing food intake (gastric procedures), affecting calorie absorption (intestinal shunting, biliopancreatic bypass), or removing localized excess fat (lipectomy, liposuction). Gastric reduction operations are safe and effective provided they are performed by experienced surgeons in well-selected patients. They can be considered now as the best option for a minority of patients with morbid and refractory obesity. Finally, in very selected patients, mechanical means (such as the waist cord) may also help losing weight and/or avoiding weight regain. Even if all these therapeutic approaches can be helpful, at least in some obese individuals, they also have important limitations so that prevention remains up to now the 'treatment' of choice for obesity. [less ▲]

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See detailENANTIOSELECTIVE SYNTHESES OF NCA (S)-L-[BETA-C-11]-4-CHLOROPHENYLALANINE AND (S)-L-(ALPHA-METHYL)-[BETA-C-11]-4-CHLOROPHENYLALANINE
Plenevaux, Alain ULg; Al-Darwich, M. J.; Lemaire, Christian ULg et al

in Applied Radiation & Isotopes (1994), 45(3), 361-369

The radiolabeling of (S)-L-4-chlorophenylalanine and (S)-L-(alpha-methyl)-4-chlorophenylalanine were realized with carbon-11 at position beta through a radiochemical synthesis relying on the highly ... [more ▼]

The radiolabeling of (S)-L-4-chlorophenylalanine and (S)-L-(alpha-methyl)-4-chlorophenylalanine were realized with carbon-11 at position beta through a radiochemical synthesis relying on the highly enantioselective reaction between 4-chloro[alpha-C-11]benzyl bromide and the lithium enolate of (S)-1-(t-butyloxycarbonyl)-2-(t-butyl)-3-methyl-1,3-imidazolidine-4-one for (S)-L-[beta-C-11]-4-chlorophenylalanine and of (2S,5S)-1-(t-butyloxycarbonyl)-2-(t-butyl)-3,5-dimethyl-1,3-imidazolidin e-4-one for (S)-L-(alpha-methyl)-[beta-C-11]-4-chlorophenylalanine. Quantities of about 25-35 mCi were obtained at the end of synthesis, ready for injection, after hydrolysis and HPLC purification with a radiochemical yield of 19% corrected to EOB within 45 min. The enantiomeric excesses were shown to be greater than or equal to 97% for both molecules without chiral separation. The radiochemical and the chemical purities of the final compounds were greater than or equal to 98% and the specific activity at the end of synthesis ranged between 250-800 mCi/mu mol. [less ▲]

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See detailMonofrequency Forced Oscillation Technique for the Investigation of Pulmonary Function in Calves: In Vitro and in Vivo Studies
Close, Roland; Reinhold, Petra; Lekeux, Pierre ULg

in Research in Veterinary Science (1994), 56(3), 363-372

Parameters derived from the non-invasive and simple monofrequency forced oscillation technique were compared with classical parameters of ventilatory mechanics in order to assess its usefulness for the ... [more ▼]

Parameters derived from the non-invasive and simple monofrequency forced oscillation technique were compared with classical parameters of ventilatory mechanics in order to assess its usefulness for the investigation of pulmonary function in calves. To facilitate this comparison, theoretical derivations were coupled with in vitro measurements, using an artificial lung model, and with in vivo studies. These studies compared the oscillatory resistance parameters (Ros and Re) and the respiratory system compliance (Crs) against the classical pulmonary resistance (RL) and the dynamic compliance (Cdyn), respectively. Ros and Re were highly correlated (r > or = 0.87) with RL and the comparison between Crs and Cdyn gave a similarly high correlation (r > or = 0.88). Given its simplicity, its correspondence with classical parameters and its rapidity and reproducibility, monofrequency forced oscillation technique seems well suited for the investigation of pulmonary function under field conditions. [less ▲]

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See detailThe Pepinster formation in the Verviers synclinorium, between Pepinster and Eupen (Belgium). Structural and stratigraphical context
Hance, Luc ULg; Dejonghe, L; Fairon-Demaret, Muriel ULg et al

in Annales de la Société Géologique de Belgique (1994), 117

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See detailMetabolic clearance rate of insulin in type 2 diabetic patients treated with combined insulin and sulfonylurea therapy.
Castillo, M. J.; Scheen, André ULg; Lefebvre, Pierre ULg

in Revista Espanola de Fisiologia (1994), 50(1), 27-34

The metabolic clearance rate of insulin (MCRI) in 10 non-obese type 2 diabetic patients treated with either insulin alone or combined insulin plus sulfonylurea therapy is investigated. A classical 2-hour ... [more ▼]

The metabolic clearance rate of insulin (MCRI) in 10 non-obese type 2 diabetic patients treated with either insulin alone or combined insulin plus sulfonylurea therapy is investigated. A classical 2-hour euglycaemic hyperinsulinaemic glucose clamp using the artificial pancreas was performed in a randomized order after two 6-week periods of treatment: either with subcutaneous injections of insulin alone or with insulin plus oral administration of the sulfonylurea compound glipizide at the dose of 3 x 10 mg/day. The MCRI was calculated knowing the constant insulin infusion rate (0.1 U.kg-1.h-1) and measuring basal and steady-state plasma free insulin and C-peptide levels. When the test was performed at the end of the period of treatment with insulin plus glipizide and 30 min after the ingestion of the last dose of 10 mg glipizide, plasma C-peptide levels were significantly increased and steady-state free insulin levels tended to be slightly higher whereas the metabolic clearance rate of glucose was not affected. The MCRI was significantly reduced by glipizide from 23.3 +/- 2.9 to 18.9 +/- 2.0 ml.kg-1.min-1 p < 0.05. These results demonstrate that the sulfonylurea glipizide decreases the MCRI. This effect may play a role in the hypoglycemic action of sulfonylureas. [less ▲]

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See detailHuman follicular dendritic cells in vitro
Tsunoda, R.; Heinen, Ernst ULg; Imai, Y. et al

in Dendritic Cells (1994), 4

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See detailLa régionalisation du droit pénal international
Flore, Daniel ULg; Thomas, F.

in Revue internationale de droit pénal (1994)

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See detailOvarian endometrial cysts: the role of gonadotropin-releasing hormone agonist and/or drainage.
Donnez, Jacques; NISOLLE, Michelle ULg; Gillerot, Stéphane et al

in Fertility and Sterility (1994), 62(1), 63-6

Objective: To evaluate the role of GnRH agonist (GnRH-a) and/or drainage in the management of large endometriomas. DESIGN: This prospective clinical study was conducted in a parallel and randomized design ... [more ▼]

Objective: To evaluate the role of GnRH agonist (GnRH-a) and/or drainage in the management of large endometriomas. DESIGN: This prospective clinical study was conducted in a parallel and randomized design. SETTING: Department of Gynecology, Cliniques Universitaires St. Luc, Brussels, Belgium. PATIENTS: Eight infertile women with laparoscopically confirmed ovarian endometriotic cysts. After laparoscopic drainage of the ovarian cyst, patients were randomized. Patients in group I (n = 40) received no therapy. Patients in group II (n = 40) received GnRH-a therapy for 12 weeks. A second-look laparoscopy was performed after 12 weeks in each woman. RESULTS: After drainage, a quick recurrence of the endometrial cyst was observed in only group I. Indeed, the score and the cyst size were similar to the values observed before the first laparoscopy. In group II, a significant decrease in score and cyst diameter was observed. Ovarian biopsies revealed significant reduction in the stromal vascularization and a significant reduction in the mitotic activity in the group of women treated with GnRH-a. CONCLUSION: The quick recurrence of the ovarian cyst after drainage proved that drainage alone is ineffective. Drainage followed by GnRH-a was effective in the reduction of cyst size and the glandular mitotic activity. [less ▲]

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See detailModeles lineaires en genetique quantitative: synthese des connaissances actuelles.
Gengler, Nicolas ULg

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(1),

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See detailQuelle stratégie pour le développement rural dans la structuration de l'espace régional?
Rondeux, Jacques ULg

in Annales de Gembloux (1994), 100(3-4), 93-107

L’espace rural comporte tellement de paramètres et de diversités et vit aujourd’hui tellement de mutations que le définir de manière précise est une gageure. On pourrait dire qu’il concerne un territoire ... [more ▼]

L’espace rural comporte tellement de paramètres et de diversités et vit aujourd’hui tellement de mutations que le définir de manière précise est une gageure. On pourrait dire qu’il concerne un territoire essentiellement agricole, à contours diffus, caractérisé par une grande diversité où l’homme y voit une source d’activités multiples, saisonnières ou complémentaires, de services gratuits et de ressources renouvelables : l’air, l’eau, le paysage. Ce n’est pas la ville, ce n’est pas le site industriel mais cela peut être les champs entre deux agglomérations, la forêt entre deux villes et surtout les grands espaces, le monde ouvert dans lequel on oublierait un peu vite que pour maintenir son originalité et valoriser ses atouts et donc se développer il doit se raccrocher à des villes, chacun tirant profit des spécificités et des potentialités de l’autre. Non au désert économique, non aux services systématiquement gratuits, non à l’absence de tissu urbain adapté ; voilà les conditions pour le maintien ou pour un oui à une agriculture revue et corrigée, à la qualité de la vie, à la beauté des paysages, aux espaces de liberté et de détente, en un mot à une nouvelle ruralité basée sur la solidarité. [less ▲]

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See detailLa gestion des données avec le logiciel V. M. S.
Claustriaux, Jean-Jacques ULg; Deltenre, Alain

in Notes de Statistique et d'Informatique (1994), 2

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See detailAnti-LFA-1 (CD11a) monoclonal antibody interferes with the induction of neonatal tolerance to alloantigens
Schurmans, Stéphane ULg; Gonzalez, A.; Revilla, C. et al

in European Journal of Immunology (1994), 24

The injection of (C57BL/6 x BALB/c)F1 spleen cells into newborn BALB/c mice results in the induction of a specific cytotoxic T lymphocyte (CTL) tolerance to the alloantigens. On the contrary, alloreactive ... [more ▼]

The injection of (C57BL/6 x BALB/c)F1 spleen cells into newborn BALB/c mice results in the induction of a specific cytotoxic T lymphocyte (CTL) tolerance to the alloantigens. On the contrary, alloreactive CD4+ T cells persist in the host and are still able to activate autoreactive F1 B cells to produce autoantibodies. This state of "split tolerance" is closely associated with the development of a lupus-like autoimmune syndrome. The LFA-1 integrin plays a relevant role in homing, intercellular adhesion and tranduction of co-stimulatory signals in leukocytes. Because of the beneficial effects of anti-LFA-1 monoclonal antibodies (mAb) treatment in various models of organ transplantation and autoimmune disease, we have investigated if such a treatment could interfere with the induction of neonatal tolerance or the development of the autoimmune syndrome in F1 cell-injected newborn mice. For this purpose, BALB/c mice neonatally injected with F1 cells were treated from day 1 up to day 15 with a non-cytotoxic anti-LFA-1 (CD11a) mAb. Anti-LFA-1 mAb treatment interfered with the persistence of a stable chimerism and with the establishment of CTL tolerance, as shown by rejection of allogeneic skin grafts and F1 B cells, and by a normal in vitro CTL activity against the corresponding alloantigens. As a consequence, these mice did not develop the characteristic autoimmune features seen in close association with an effective induction of CTL tolerance to alloantigens. These results stress the importance of the interactions between LFA-1 and its ligands during the neonatal induction of tolerance to alloantigens [less ▲]

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See detailLongwave Sky Radiation Parametrizations
Aubinet, Marc ULg

in Solar Energy (1994), 53(2),

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See detailcerebral blood flow velocities measurements on anterior cerebral artery during general anesthesia and minor surgery
Battisti, Oreste ULg

in Circulation et Métabolisme du Cerveau (1994), 11

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See detailTraducteurs et traductions dans l'Egypte gréco-romaine
Rochette, Bruno ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1994), 69(138), 313-322

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See detailMax Ophuls : le cristal et la tache
Belloi, Livio ULg

in Cinémathèque (1994), 6(automne),

Cette étude porte sur les quatre derniers films de Max Ophuls ("La Ronde", "Le Plaisir", "Madame de" et "Lola Montès") et s'attache à révéler, en eux, une forme de dilemme du visible (entre transparence ... [more ▼]

Cette étude porte sur les quatre derniers films de Max Ophuls ("La Ronde", "Le Plaisir", "Madame de" et "Lola Montès") et s'attache à révéler, en eux, une forme de dilemme du visible (entre transparence et opacité) que la modernité cinématographique inscrira résolument à son ordre du jour. [less ▲]

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See detailLe chylothorax et son traitement
Detry, Olivier ULg; Dekoster, Guy ULg; Limet, Anne ULg

in Lyon Chirurgical (1994), 90(1), 38-44

Chylothorax is an unfrequent pathology defined by fistula between the thoracic duct and one of the pleura. Its spontaneous evolution is worse, with respiratory failure in the acute phase. After a few days ... [more ▼]

Chylothorax is an unfrequent pathology defined by fistula between the thoracic duct and one of the pleura. Its spontaneous evolution is worse, with respiratory failure in the acute phase. After a few days of thoracic tube drainage, hemodynamic, nutritional and immunologic disturbances appear. Since the first thoracic duct ligature by Lampson in 1948, surgical approach has obviously reduced the morbidity and mortality of chylothorax. The new development of the thoracoscopic techniques will allow earlier and less aggressive surgical treatment. However, thoracic surgeons must keep in mind that every intrathoracic operation could induce chylothorax, especially in case of posteriror mediastinal surgery. Chylothorax must be evocated if unusually profuse milky pleural effusion complicate this type of procedure. We discribe the anatomy and the physiology of chylous circulation and we discuss the etiologies and the different therapeutic approaches of chylothorax. [less ▲]

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See detailHereditary muscular hypertrophy in cattle is associated with a reduced myocardial contractility
Amory, Hélène ULg; Mc Entee, Kathleen ULg; Linden, Annick ULg et al

in Pflügers Archiv : European Journal of Physiology (1994), 426

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See detailA Comparison of Cabergoline and Bromocriptine in the Treatment of Hyperprolactinemic Amenorrhea
Webster, J.; Piscitelli, G.; Polli, A. et al

in New England Journal of Medicine [=NEJM] (1994), 331(14), 904-909

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See detailImmunological detection of beta-galactosidase-expressing cells by flow cytometry
Vanderplasschen, Alain ULg; Goltz, M.; Hanon, E.

in Biochemica (1994), 3

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See detailDe l'école à l'entreprise ou le processus d esocialisation mis en échec
Robert, Jocelyne ULg

in Eucation-Formation (1994)

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See detailNew Energy Levels in Ne II deduced from FTS spectra in the Infrared Region (1800-9000 cm-1)
Quinet, Pascal ULg; Palmeri, P.; Biémont, Emile ULg

in Physica Scripta (1994), 49

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See detailLes fleurs pâles du souvenir... Sur Guillaume Lekeu
Pirenne, Christophe ULg; Vendrix, Philippe ULg

in La Vie Wallonne (1994), 110

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See detailHeterogeneous conversion of N2O5 to HNO3 in the post-Mount Pinatubo eruption stratosphere
Rinsland, Curtis P.; Gunson, Michaël R.; Abrams, M. C. et al

in Journal of Geophysical Research (1994), 99(D4), 8213-8219

Simultaneous stratospheric volume mixing ratio (VMR) profiles of dinitrogen pentoxide (N2O5) and nitric acid (HNO3) at sunrise between 25-degrees-N and 15-degrees-S latitude and profiles of HNO3 at sunset ... [more ▼]

Simultaneous stratospheric volume mixing ratio (VMR) profiles of dinitrogen pentoxide (N2O5) and nitric acid (HNO3) at sunrise between 25-degrees-N and 15-degrees-S latitude and profiles of HNO3 at sunset between 42-degrees-S and 53-degrees-S latitude have been derived from 0.01 cm-1 resolution infrared solar occultation spectra recorded 9 1/2 months after the massive eruption of the Mount Pinatubo volcano in the Philippine Islands. The measurements were obtained by the atmospheric trace molecule spectroscopy (ATMOS) Fourier transform spectrometer during the ATLAS 1 shuttle mission (March 24 to April 2, 1992). The measured HNO3 VMRs are higher at all altitudes and latitudes than corresponding values measured by the limb infrared monitor of the stratosphere (LIMS) instrument during the same season in 1979, when the aerosol loading was near background levels. The largest relative increase in the HNO3 VMR occurred near the equator at 30-km altitude, where the ATMOS/ATLAS 1 values are about a factor of 2 higher than the LIMS measurements. Two-dimensional model calculations show that the increase in HNO3 and the ATMOS/ATLAS 1 measurement of a steep decrease in the N2O5 VMR below 30 km can be explained by the enhanced conversion of N2O5 to HNO3 on the surfaces of the Mount Pinatubo sulfate aerosols. Our profile results demonstrate the global impact of the N2O5 + H2O --> 2HNO3 heterogeneous reaction in altering the partitioning of stratospheric odd nitrogen after a major volcanic eruption. [less ▲]

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See detailOxygen Transport Chain in Double-Muscled Blue Belgian Cattle
Lekeux, Pierre ULg; Amory, Hélène ULg; Desmecht, Daniel ULg et al

in British Veterinary Journal (The) (1994), 150(5, Sep-Oct), 463-471

The physiological peculiarities of the oxygen transport chain in double-muscled Blue Belgian cattle are described. The investigations performed at several levels of the oxygen transport chain suggest that ... [more ▼]

The physiological peculiarities of the oxygen transport chain in double-muscled Blue Belgian cattle are described. The investigations performed at several levels of the oxygen transport chain suggest that the increased susceptibility of these cattle to stress, resulting mainly in respiratory diseases, is due to an insufficient functional reserve capacity mainly involving the pulmonary and cardiovascular systems. The resulting lack of 'functional hardiness' of the oxygen transport chain is seen in those double-muscled cattle which do not react in an appropriate or predictable way when submitted to a hostile environment. [less ▲]

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See detailRedox Mechanism For The Chaperone Activity Of Heat-Shock Proteins Hsp-60, Hsp-70 And Hsp-90 As Suggested By Hydrophobic Cluster-Analysis - Hypothesis
Callebaut, I.; Catelli, Mg.; Portetelle, Daniel ULg et al

in Comptes Rendus de l'Académie des Sciences. Série III, Sciences de la Vie (1994), 317(8),

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See detailEffect of dopamine and baclofen on N-methyl-D-aspartate-induced burst firing in rat ventral tegmental neurons.
Seutin, Vincent ULg; Johnson, S. W.; North, R. A.

in Neuroscience (1994), 58(1), 201-6

Intracellular microelectrode recordings were made from dopamine-containing neurons of the ventral tegmental area or substantia nigra zona compacta in rat brain slices in vitro. The firing pattern of the ... [more ▼]

Intracellular microelectrode recordings were made from dopamine-containing neurons of the ventral tegmental area or substantia nigra zona compacta in rat brain slices in vitro. The firing pattern of the neurons was switched from a tonic, single-spike pattern to a burst firing mode by adding N-methyl-D-aspartate (20 microM) to the superfusing solution; after adding tetrodotoxin the membrane potential underwent rhythmical oscillations of 20-40 mV at 0.5-2 Hz. Baclofen (1 microM) and dopamine (30 microM) hyperpolarized the neurons; when the potential was restored to its original level, the oscillations of potential and/or burst firing were not observed, but the tonic firing pattern was restored. These effects of baclofen and dopamine were prevented by barium (1 mM), which also prevented the membrane hyperpolarization. Oscillations of membrane current of a similar frequency were observed when the somatic membrane was voltage-clamped at -60 mV; these were also blocked by barium (1 mM). It is concluded that the oscillations in membrane potential observed with N-methyl-D-aspartate are generated predominantly at a dendritic location which is not voltage-clamped with an electrode at the soma. Baclofen and dopamine inhibit the oscillations by increasing the potassium conductance and hyperpolarizing the dendrites. [less ▲]

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See detailAdvanced endoscopic techniques used in dysfunctional bleeding, fibroids and endometriosis, and the role of gonadotrophin-releasing hormone agonist treatment.
Donnez, Jacques; NISOLLE, Michelle ULg; Clerckx, Françoise et al

in British Journal of Obstetrics & Gynaecology (1994), 101(suppl 10), 2-9

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See detailUniversal scaling laws and the QCD scale anomaly
Ripka, Georges; Jaminon, Martine ULg

in Physics Reports (1994), 242

An effective chiral Lagrangian is given which implements the QCD scale anomaly and the universal scaling law of hadron masses. It is used to study the pion mass and the coupling between quark and gluon ... [more ▼]

An effective chiral Lagrangian is given which implements the QCD scale anomaly and the universal scaling law of hadron masses. It is used to study the pion mass and the coupling between quark and gluon condensates in dense matter. [less ▲]

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See detailMultiphase Saturation Curves of the Oxoglutarate Carrier : A mathematical Model
Holzhütter, H.-G.; Sluse-Goffart, C.; Sluse, Francis ULg

in Mathematical & Computer Modelling (1994), 19(6-8), 263-272

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See detailCo-movements and dynamic interrelationships in pacific basin stock markets
Corhay, Albert ULg; Tourani-Rad, Alireza; Urbain, Jean-Pierre ULg

in Research in International Business and Finance (1994), 11B

In this paper, we investigate dynamic interrelationships among the stock markets of Australia, Hong Kong, Japan, New Zealand and Singapore. Using cointegration analysis and the Granger causality test we ... [more ▼]

In this paper, we investigate dynamic interrelationships among the stock markets of Australia, Hong Kong, Japan, New Zealand and Singapore. Using cointegration analysis and the Granger causality test we find that, although the five stock price indices share some common trends, the only stock price which does not apparently Granger cause (precede) the remaining stock prices is that of New Zealand. It is further observed that all price indices are caused by the remaining stock prices except that of Australia. With respect to the geographical separation, it appears that when we consider the Asian countries as an entity and those of the Pacific as another entity, they seem not to influence each other significantly. [less ▲]

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See detailL’éthique et l’animal. Eléments pour un débat
Ansay, M.; Delaunois, A.; Gustin, Pascal ULg

in Annales de Médecine Vétérinaire (1994), 138

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