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See detailInfluence des facteurs individuels et de troupeau sur les performances de reproduction bovine
Hanzen, Christian ULg; Houtain, J. Y.; Laurent, Y. et al

in Annales de Médecine Vétérinaire (1996), 140

Through a wide review of the litterature (330 references), the authors have tried to describe the determinant or predisposing effects of factors usually involved in the reproduction problems in beef or ... [more ▼]

Through a wide review of the litterature (330 references), the authors have tried to describe the determinant or predisposing effects of factors usually involved in the reproduction problems in beef or dairy cattle. These factors have been qualified as individual or herd factors. The first ones involve the animal itself like age, genetic, milk production level, dystocia, twinning, perinatal mortality, placental retentio, milk fever, uterine involution, metritis, post-partum ovarian activity. The second ones concern the environnement of the animal i.e. first insemination policy, oestrus detection, insemination time and technic, nutrition, season, stabulation, herd size or management capacity of the farmer. The authors conclude to the multifactorial etiology of the reproduction pathologies. It also appears necessary to develop data collection systems like herd health management programs. Such systems should be able to offer to the practitionner the opportunity to be involved more efficiently in the economic health of the herd using epidemiological tools to study the different implied factors. [less ▲]

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See detailUne banque de questions au service de l'évaluation formative dans l'enseignement technique du deuxième degré
Denis, Brigitte ULg; Bosmans, Catherine ULg; Jans, Véronique

in Informations pédagogiques (1996), (22), 23-33

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See detailDissociation of increases in plasma insulin-like growth factor I and testosterone during the onset of puberty in bulls
Renaville, Robert ULg; Massart, Serge; Sneyers, M. et al

in Journal of Reproduction and Fertility (1996), 106(1), 79-86

The present study was conducted to examine the relationship between plasma concentrations of testosterone, insulin-like growth factor I (IGF-I) and IGF-binding proteins (IGFBPs) during puberty, in male ... [more ▼]

The present study was conducted to examine the relationship between plasma concentrations of testosterone, insulin-like growth factor I (IGF-I) and IGF-binding proteins (IGFBPs) during puberty, in male calves treated with GnRH or testosterone propionate. Twelve male Holstein calves (10 weeks old) were assigned to the control group (n = 6), the GnRH-treated group (n = 3) or the testosterone-treated group (n = 3). For 8 weeks, the GnRH-treated group received a single i.v. injection of GnRH (0.5 mu g kg(-1) body mass) each day while the testosterone-treated group received an i.m. injection of testosterone propionate (0.5 mg kg(-1) body mass) twice a day. The calves were studied until they were 200 days old. Hormone treatments were stopped one month after puberty was reached in the control group. Blood samples were collected every 30 min for 8 h every third day. Hormone concentrations were determined by radioimmunoassay. Western ligand blotting and immunoblotting, using monoclonal antibodies against IGFBP-2, and IGFBP-3, were used to characterize the IGF-binding proteins. In the control group, puberty occurred at about 120 days of age and was associated with an increase in concentrations of testosterone, IGF-I and IGFBP-3 and a decrease in concentration of IGFBP-2. In the GnRH-treated group, plasma testosterone remained low until 8 weeks after establishment of puberty in the control group (4 weeks after the end of treatment). In the testosterone-treated group, testosterone was high during the treatment period and then decreased to prepubertal values when treatment was stopped. Testosterone values increased again to reach postpubertal values 5 weeks after the end of hormone treatment. Nevertheless, independent of testosterone status, the profile of IGF-I and the IGFBPs in the GnRH- and testosterone-treated groups were parallel to that reported for the control group with the transition from prepubertal to adult values at about 120 days of age. In conclusion, concentrations of testosterone, IGF-I and IGFBP-3 increase together, but probably independently, during the onset of puberty in male calves. [less ▲]

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See detailAnalysis of structural members under elevated temperature conditions- Discussion
Franssen, Jean-Marc ULg

in Journal of Structural Engineering (1996), 10

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See detailModélisation en hydrogéologie - De modelisatie in de hydrogeologie
Dassargues, Alain ULg; Vander Velpen, B.; Vercruysse, J.

in BLUG Tijdschrift - Revue de l'UBLG (1996)

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See detailThe Use Of N-15-Labeled Dietary Proteins For Determining True Ileal Amino Acid Digestibilities Is Limited By Their Rapid Recycling In The Endogenous Secretions Of Pigs
Leterme, Pascal; Thewis, André ULg; Francois, Etienne et al

in Journal of Nutrition (1996), 126(9), 2188-2198

We assessed the use of 15N-labeled dietary proteins as a possible tool for the determination of the true ileal amino acid (AA) digestibility in pigs. The first experiment was designed to study the dietary ... [more ▼]

We assessed the use of 15N-labeled dietary proteins as a possible tool for the determination of the true ileal amino acid (AA) digestibility in pigs. The first experiment was designed to study the dietary N excretion pattern at the ileum subsequent to the ingestion of a single 15N-labeled meal. In a second experiment, we compared ileal endogenous AA outputs and true AA digestibility estimates obtained in pigs ingesting 15N-labeled dietary proteins in a single meal vs. intravenous infusion of 15N-leucine for 10 d during the ingestion of a pea-based diet and a protein-free starch diet. The proportion of endogenous N found in the ¡leal digesta differed when the label was delivered orally (50%) vs. intravenously (72%) and changed with time. As a consequence, the true ileal AA digestibilities measured with labeled diets were lower. A third experiment demonstrated that this was due to the rapid recycling of labeled dietary N in endogenous moieties, because 15N was found in blood within 10 min of consuming the labeled meal, within 50 min of consumption in pancreatic enzymes, 90 min in bile and 4 h in ¡leal mucins. We conclude that the use of 15N-labeled meals for determination of true ¡leal AA digestibilities is limited by the fast recycling of dietary N in endogenous secretions following a single 15N-labeled meal. The accuracy of results will depend on meaningful estimates of AA flow during a limited period and accurate estimates of 15N in AA. [less ▲]

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See detailSimulation of pumping and artificial recharge in the phreatic aquifer near Bucarest (Romania)
Stefanescu, Christian; Dassargues, Alain ULg

in Hydrogeology Journal (1996), 4(3), 72-83

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See detailLa place actuelle de l'immunoanalyse en Toxicologie Clinique
Charlier, Corinne ULg; Plomteux, Guy ULg

in Immuno-Analyse & Biologie Spécialisée [=IBS] (1996), 11

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See detailIntérêt de l'acide rétinoïque "tous trans" dans le traitement de la leucémie aiguë promyélocytaire
Hermanne, J.-P.; Tassin, F.; Bours, Vincent ULg et al

in Médecine et Hygiène (1996), 54

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See detailForeword
Fontana, Roberta; Canepari, Pietro; Ghuysen, Jean-Marie ULg

in Microbial Drug Resistance : Mechanism, Epidemiology, & Disease (1996), 2(1), 5-5

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See detailCrystallization and preliminary X-ray diffraction studies of a-amylase from the antarctic psychrophile Alteromonas haloplanctis A23
Aghajari, N.; Feller, Georges ULg; Gerday, Charles ULg et al

in Protein Science : A Publication of the Protein Society (1996), 5(10), 2128-2129

A cold-active alpha-amylase was purified from culture supernatants of the antarctic psychrophile Alteromonas haloplanctis A23 grown at 4 degrees C. In order to contribute to the understanding of the ... [more ▼]

A cold-active alpha-amylase was purified from culture supernatants of the antarctic psychrophile Alteromonas haloplanctis A23 grown at 4 degrees C. In order to contribute to the understanding of the molecular basis of cold adaptations, crystallographic studies of this cold-adapted enzyme have been initiated because a three-dimensional structure of a mesophilic counterpart, pig pancreatic alpha-amylase, already exists. alpha-Amylase from A. haloplanctis, which shares 53% sequence identity with pig pancreatic alpha-amylase, has been crystallized and data to 1.85 A have been collected. The space group is found to be C222(1) with a = 71.40 A, b = 138.88 A, and c = 115.66 A. Until now, a three-dimensional structure of a psychrophilic enzyme is lacking. [less ▲]

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See detailRelationship of Plasma Lactate Production to Cortisol Release Following Completion of Different Types of Sporting Events in Horses
Desmecht, Daniel ULg; Linden, Annick ULg; Amory, Hélène ULg et al

in Veterinary Research Communications (1996), 20(4), 371-379

Fifty-eight healthy horses were studied during five sporting events of various intensities and durations, namely show-jumping (n = 6), cross-country in a three-day event (n = 30), trotting races (n = 7 ... [more ▼]

Fifty-eight healthy horses were studied during five sporting events of various intensities and durations, namely show-jumping (n = 6), cross-country in a three-day event (n = 30), trotting races (n = 7), galloping races (n = 7) and endurance rides (n = 8). Venous blood samples were collected at rest and immediately after exercise and analysed for plasma cortisol (CORT) and lactate (LA) levels. The experimental procedure was the same throughout the investigation so as to permit a reliable comparison between the five types of exercise. The type of event significantly affected both the resting (p < or = 0.05) and the post-exercise (p < or = 0.01) plasma CORT. The degree of exercise-induced hypercortisolaemia was related to both the intensity and the duration of exercise for all five sporting events, but the endurance ride induced the most and show-jumping the least serious post-exercise CORT changes. LA production was much more closely related to the intensity of the exercise than was CORT. It is concluded that simultaneous measurements of plasma CORT and LA levels may be useful to discriminate between different types of exercise, adjust training programmes, and improve our comprehension of the physiology of sport horses at exercise. [less ▲]

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See detailIntestinal Permeability in Crohn's Disease
Franchimont, D.; Louis, Edouard ULg; Simon, Sarah ULg et al

in Acta Gastro-Enterologica Belgica (1996), 59(1, Jan-Mar), 15-9

We summarize the anatomical and physiological basis and the ways of measuring the intestinal permeability. We review the studies of the intestinal permeability in Crohn's disease. We analyse the ... [more ▼]

We summarize the anatomical and physiological basis and the ways of measuring the intestinal permeability. We review the studies of the intestinal permeability in Crohn's disease. We analyse the involvement of an abnormal intestinal permeability in the pathogenesis of Crohn's disease, as a primary or secondary defect. We discuss the potential usefulness of the measure of intestinal permeability in Crohn's disease activity assessment, relapse prediction and efficacy of treatment. [less ▲]

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See detailInteraction Of The Macrolide Azithromycin With Phospholipids .2. Biophysical And Computer-Aided Conformational Studies
Montenez, Jp.; Vanbambeke, F.; Piret, J. et al

in European Journal of Pharmacology (1996), 314(1-2), 215-27

In a comparison paper, we show the azithromycin causes a lysosomal phospholipidosis in cultured cells, binds in vitro to negatively charged bilayers without causing aggregation or fusion, and inhibits ... [more ▼]

In a comparison paper, we show the azithromycin causes a lysosomal phospholipidosis in cultured cells, binds in vitro to negatively charged bilayers without causing aggregation or fusion, and inhibits lysosomal phospholipase A1. In this paper, we show that azithromycin decreases the mobility of the phospholipids in negatively charged liposomes (using 31P nuclear magnetic resonance) and that it increases the fluidity of the acyl chains close to the hydrophilic/hydrophobic interface, but not deeper into the hydrophobic domain (assessed by measuring the fluorescence polarization of trimethylammonium-diphenylhexatriene and diphenyhexatriene, respectively). Computer-aided conformational analysis of mixed monolayers of azithromycin and phosphatidylinositol shows that the drug can be positioned largely in the hydrophobic domain, but close to the interface, with the macrocycle facing the C1 of the fatty acids (allowing the N9a endocyclic tertiary amine to interact with the phospho-groups), the cladinose located on the hydrophobic side of the lipid/water interface and the desosamine projected into the hydrophobic domain. This position is consistent with the experimental data. Analysis of virtual molecules shows that this unanticipated behavior to the shielding of the ionizable N3' amino-group in the desosamine by methyl-groups, and to the wide dispersion of hydrophobic domains all over the molecule. The interaction of azithromycin with phospholipids may account for some of its unusual pharmacokinetic properties and for its potential to cause lysosomal phospholipidosis. [less ▲]

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See detailTwo rare European Ephemerum species (Bryophita): E. cohaerens rediscovered near Strasbourg (France) and E. stellatum new to Belgium
Vanderpoorten, Alain ULg; Stieperaere, H.; Klein, J.-P.

in Belgian Journal of Botany (1996), 129

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See detailRecommendations for the registration of agents used in the prevention and treatment of glucocorticoid-induced osteoporosis
Compston, JE; Audran, M; Avouac, B et al

in Calcified Tissue International (1996), 59

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See detailPremière approche de la flore macrolichénique corticole de la Région de Bruxelles-Capitale en situation de dépollution au SO2
Tanghe, Martin; Richel, Thierry; Crisan, Florin et al

in Belgian Journal of Botany (1996), 129

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See detailThe Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock
Georges, Michel ULg; Cockett, N.

in Reproduction Nutrition Development (1996), 36(6), 651-7

An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge (CLPG) gene mapped to ovine chromosome 18. We demonstrate in this work that the callipyge ... [more ▼]

An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge (CLPG) gene mapped to ovine chromosome 18. We demonstrate in this work that the callipyge phenotype is characterized by a non-Mendelian inheritance pattern, referred to as polar overdominance, in which only heterozygous individuals having inherited the CLPG mutation from their sire express the phenotype. The possible role of parental imprinting in the determinism of polar overdominance is envisaged. [less ▲]

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See detailImpairement of Memory for Spatial Context in Schizophrenia
Van der Linden, Martial ULg; Rohmer, J.G.; Rizzo, L. et al

in Neuropsychology (1996), 10

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See detailA simple technique to relieve Tribolium castaneum (Coleoptera: Tenebrionidae) of Acarophenax tribolii (Acarina: Pyemotidae).
Arnaud, Ludovic; Mignon, Jacques ULg; Gilson, Jean-Claude et al

in Tribolium Information Bulletin (1996), 36

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See detailHigh neuron specific enolase levels in bronchoalveolar lavage fluid of patients with lung carcinoma: diagnostic value, relation to serum neuron specific enolase, and staging.
Dowlati, A; Bury, Thierry ULg; CORHAY, Jean-Louis ULg et al

in Cancer (1996), 77(10), 2039-43

BACKGROUND: High levels of neuron specific enolase (NSE) have recently been described in the bronchoalveolar lavage (BAL) fluid of patients with lung carcinoma. Although its value in serum has been ... [more ▼]

BACKGROUND: High levels of neuron specific enolase (NSE) have recently been described in the bronchoalveolar lavage (BAL) fluid of patients with lung carcinoma. Although its value in serum has been extensively studied, its diagnostic value in BAL fluid in terms of sensitivity, specificity, and predictive value have not been evaluated. In addition, its value in staging and relation to serum NSE are yet unknown. METHODS: NSE levels were determined on the same day in the BAL fluid and the sera of two groups of patients: those with newly diagnosed lung carcinoma and those with smoking related chronic obstructive pulmonary disease (COPD). Clinical TNM staging was also performed. Levels of NSE in BAL fluid were expressed as nanograms per 100 international units of lactate dehydrogenase. BAL fluid NSE levels of the two groups were compared with staging and serum NSE. RESULTS: A highly significant difference exists in BAL NSE in the two groups. For diagnostic purposes, the simultaneous measurements of serum NSE increases its sensitivity, but specificity remains unchanged. No correlation exists between BAL NSE and serum NSE, tumor size, nodal status, or the presence of metastases. BAL NSE is a better predictor of malignancy than serum NSE. CONCLUSION: BAL fluid measurements of NSE may have diagnostic value, specially if it is simultaneously measured in the serum. However, our study does not show any value for this technique in staging of lung carcinoma. Also it has no correlation with serum NSE. Studies will have to be performed to determine if BAL NSE can predict chemotherapeutic sensitivity. [less ▲]

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See detailLifetimes of the 3d2D levels in Ca II
Biémont, Emile ULg; Zeippen, C. J.

in Comments on Atomic and Molecular Physics (1996), 33

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See detailHeparin-coated Palmaz-Schatz stents in human coronary arteries. Early outcome of the Benestent-II Pilot Study.
Serruys, P. W.; Emanuelsson, H.; van der Giessen, W. et al

in Circulation (1996), 93(3), 412-22

BACKGROUND: The purpose of the Benestent-II Pilot Study was to evaluate the safety of delaying and eliminating anticoagulant therapy in patients receiving a heparin-coated stent in conjunction with ... [more ▼]

BACKGROUND: The purpose of the Benestent-II Pilot Study was to evaluate the safety of delaying and eliminating anticoagulant therapy in patients receiving a heparin-coated stent in conjunction with antiplatelet drugs. METHODS AND RESULTS: The study consisted of three initial phases (I, II, III) during which resumption of heparin therapy after sheath removal was progressively deferred by 6, 12, and 36 hours. In phase IV, coumadin and heparin were replaced by 250 mg ticlopidine and 100 mg aspirin. Of the 207 patients with stable angina pectoris and a de novo lesion in whom heparin-coated stent implantation was attempted, implantation was successful in 202 patients (98%). Stent thrombosis did not occur during all four phases, and the overall clinical success rate at discharge was 99%. Bleeding complications requiring blood transfusion or surgery fell from 7.9% in phase I to 5.9%, 4%, and 0% in the three following phases. Hospital stay was 7.4, 6.1, 7.2, and 3.1 days for the consecutive phases. The restenosis rate for the combined four phases was 13% (15% in phase I, 20% in phase II, 11% in phase III, and 6% in phase IV). The overall rate of reintervention for the four phases was 8.9%. At 6 months, 84%, 75%, 94%, and 92% of the patients of phases I to IV, respectively, were event free. For the four phases, the event-free rate was 86%, which compares favorably with the rate observed in the Benestent-I study (80%; relative risk, 0.68 [0.45 to 1.04]). CONCLUSIONS: The implantation of stents coated with polyamine and end-point-attached heparin in stable patients with one significant de novo coronary lesion is well tolerated, is associated with no (sub)acute stent thrombosis, and results in a favorable event-free survival after 6 months. [less ▲]

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See detailThe development of a European questionnaire for quality of life in patients with vertebral osteoporosis
Lips, P; Agnusdei, D; Caulin, F et al

in Scandinavian Journal of Rheumatology (1996), 25(103), 84-85

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See detailThe lichen genus Lecanactis and allied genera in Papua New Guinea
Egea, J.M.; Sérusiaux, Emmanuël ULg; Torrente, Pilar

in Mycotaxon (1996), 59

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See detailChronic Exposure of Pigs to Airborne Dust and Endotoxins in an Environmental Chamber: Technical Note
Urbain, B.; Prouvost, J. F.; Beerens, Dominique ULg et al

in Veterinary Research (1996), 27(6), 569-578

A new experimental setup was developed to expose pigs to dust and airborne endotoxins in an environmental chamber, at levels liable to be encountered in pig farm buildings. The following parameters were ... [more ▼]

A new experimental setup was developed to expose pigs to dust and airborne endotoxins in an environmental chamber, at levels liable to be encountered in pig farm buildings. The following parameters were evaluated in a chamber containing two pigs of 10 kg body-weight: inhalable and respirable dust gravimetric concentrations were measured using area samplers and expressed as mg/m3. The respirable dust concentration was also measured using a "TM digital microP respirable dust-measuring instrument', which has been shown to give similar results to the gravimetric method. The endotoxin concentration was evaluated using the Limulus-assay and expressed as ng/m3 of air containing the inhalable or respirable dust or as ng/mg of inhalable and respirable dust. Feed flour dust was introduced into the chamber to obtain different concentrations of inhalable and respirable dust ranging from 3.62 to 76.66 mg/m3 and from 0.24 to 1.40 mg/m3, respectively. The endotoxin concentration was modulated by mixing the feed flour with Escherichia coli endotoxins before blowing it into the chamber. The endotoxin concentrations in the air containing inhalable or respirable dust ranged from 28.9 to 270.0 ng/m3 and from 2.22 to 36.38 ng/m3, respectively, depending on the amount of endotoxins added to the dust. Data were also obtained in a piggery. The experimental setup detailed in this paper could be used to study the significance of air contaminants in the development of pig respiratory diseases. [less ▲]

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See detailBenard-Marangoni instability in rigid rectangular containers
Dauby, Pierre ULg; Lebon, Georgy ULg

in Journal of Fluid Mechanics (1996), 329

Not Available

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See detailMaladie pulmonaire obstructive chronique dans l'espèce équine
Vandenput, Sandrina ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1996), 140

Equine chronic obstructive pulmonary disease (COPD), also known as <<heaves>>, is a respiratory syndrome associated with stabling or exposure to hay or conditions in which molds or dust prevail. This ... [more ▼]

Equine chronic obstructive pulmonary disease (COPD), also known as <<heaves>>, is a respiratory syndrome associated with stabling or exposure to hay or conditions in which molds or dust prevail. This paper reviews the different aspects of the equine COPD. Etiology, potential evolutions, treatment and prevention of this disease are evolved. [less ▲]

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See detailTribology in Aerospace Propulsion Mechanisms
Bozet, Jean-Luc ULg

in Space Scientific Research in Belgium, vol. IV : Space Technology (1996), 4

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See detailDescription lithostratigraphique et pétrographie du sondage 221E87 de Villers-devant-Orval (Trias, Lias de la Gaume, Belgique)
Boulvain, Frédéric ULg; Delsate, D.; Gulinck, M. et al

in Professional Paper Belgian Geological Survey (1996), 281

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See detailActivités sportives et système immunitaire
PIRNAY, Freddy ULg; Bury, Thierry ULg

in Médecine et Hygiène (1996), 54

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See detail"Aquí, allá y en todas partes": La (con)version de la Identidad Caribeña por Michelle Cliff
Ledent, Bénédicte ULg; Ortega, María Teresa

in Anales del Caribe (1996), 16-18

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See detailA New Equilibrium Cell with Variable Cell Volume for Static Vapour-Pressure Measurements
Gaube, J; Hammer, S; Pfennig, Andreas ULg

in Fluid Phase Equilibria (1996), 123((1-2)), 245-257

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See detailTransition probabilities for forbidden lines of Fe III
Quinet, Pascal ULg

in Astronomy and Astrophysics. Supplement Series (1996), 116

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See detailDescription des plantules de quatre Caesalpiniacées africaines
Léonard, J.; Doucet, Jean-Louis ULg

in Bulletin du Jardin Botanique National de Belgique = Bulletin van de Nationale Plantentuin van België (1996), 66

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See detailDémarche préventive d'une école du dos
Vanderthommen, Marc ULg; Drosson, C.; TOMASELLA, Marco ULg et al

in Kine 2000 (1996), 5(7),

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See detailDistribution of surface water partial CO2 pressure in the English Channel and in the Southern Bight of the North Sea
Frankignoulle, Michel; Bourge, Isabelle; Canon, Christine ULg et al

in Continental Shelf Research (1996), 16

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See detailMembrane-type matrix metalloproteinase-1 expression at the site of human placentation
Nawrocki, B.; Polette, M. E.; Marchand, V. et al

in Placenta (1996), 17(8), 565-72

Human trophoblast implantation is a highly regulated process of invasion that requires action of proteolytic enzymes to degrade extracellular matrix components of the endometrium. Among these enzymes ... [more ▼]

Human trophoblast implantation is a highly regulated process of invasion that requires action of proteolytic enzymes to degrade extracellular matrix components of the endometrium. Among these enzymes, matrix metalloproteinases (MMPs) seem to be particularly important in this degradative process. We previously showed that gelatinase A is extensively expressed in vivo in the human placenta. A new MMP, MT-MMP-1 (membrane-type matrix metalloproteinase-1), which is thought to activate progelatinase A, has recently been described. In this study, we examined the expression of MT-MMP-1, by immunohistochemistry and in situ hybridization, in human placental bed biopsies taken during the first trimester of gestation. Human first trimester intermediate trophoblasts synthesized MT-MMP-1 mRNAs and the protein. The MT-MMP-1 pattern of distribution in placental beds was similar to that of gelatinase A, suggesting a pivotal role for MT-MMP-1 in placentation, perhaps by activating progelatinase A. [less ▲]

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See detailInfluence of Van Hove singularity on the electronic specific heat of high-Tc superconductors
Dorbolo, Stéphane ULg; Houssa, Michel; Ausloos, Marcel ULg

in Physica C: Superconductivity (1996)

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See detailDe la phrase au texte dans l'enseignement d'une langue étrangère
Defays, Jean-Marc ULg

in Dialogues et cultures (1996), 40

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See detailMarginalia Vergiliana
Rochette, Bruno ULg

in Zeitschrift für Papyrologie und Epigraphik (1996), 114

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See detailSexual differentiation of odor and partner preference in the rat.
Bakker, Julie ULg; Van Ophemert, J.; Slob, A. K.

in Physiology & Behavior (1996), 60(2), 489-94

Previous studies have shown that adult male rats, in which brain estrogen formation was inhibited neonatally by SC administration of the aromatase inhibitor 1,4, 6-androstatriene-3,17-dione (ATD), show an ... [more ▼]

Previous studies have shown that adult male rats, in which brain estrogen formation was inhibited neonatally by SC administration of the aromatase inhibitor 1,4, 6-androstatriene-3,17-dione (ATD), show an altered sexual partner preference. When tested in a three-compartment box, such gonadally intact ATD males approach and mate both with the estrous female and the sexually active male, whereas normal males prefer to approach and mate with the estrous female, avoiding the stimulus male. After castration in adulthood and estradiol treatment, ATD males prefer sexually active males. Similarly treated normal males prefer estrous females, and estrous females prefer to mate with males. In the present study, we asked what stimulus characteristics of active males vs. estrous females determined the different sexual preferences of males, ATD males, and of females. Were they chemosensory cues or more distal cues such as actually seeing and hearing the stimulus animals or the reward of sexual activity with the stimulus animals? Sex differences in preference were evident when animals were given a choice between soiled bedding from estrous females and from sexually active males. ATD and control males spent significantly more time on soiled bedding from estrous females than on soiled bedding from sexually active males. Control females spent significantly more time on soiled bedding from sexually active males than on soiled bedding from estrous females. More distal cues, such as seeing and hearing the stimulus animals, revealed differences in preference between control males and females, but not between ATD and control males. Physical interaction with the stimulus animals was a prerequisite for revealing differences in preference between ATD and control males. Then, the behavior of ATD males was clearly intermediate between that of normal male and female rats. In conclusion, neonatal estradiol is important for the psychosexual development of the male rat. However, the present data suggest that the psychosexual development of the male rat also requires either prenatal estradiol or perinatal testosterone. [less ▲]

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See detailOscillator strengths for Ca-like iron, cobalt and nickel (Fe VII, Co VIII, Ni IX)
Quinet, Pascal ULg; Hansen, J E

in Journal of Physics : B Atomic Molecular & Optical Physics (1996), 29

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See detailChemical Composition Of Pea Fibre Isolates And Their Effect On The Endogenous Amino Acid Flow At The Ileum Of The Pig
Leterme, Pascal; Thewis, André ULg; Van leeuwen, Piet et al

in Journal of the Science of Food and Agriculture (1996), 72(1), 127-134

Pea starch, hulls and cotyledon inner fibres, isolated from pea seeds, were incorporated in N-free diets, on a NDF-content basis, in order to study their effect on the ileal endogenous amino acid (AA ... [more ▼]

Pea starch, hulls and cotyledon inner fibres, isolated from pea seeds, were incorporated in N-free diets, on a NDF-content basis, in order to study their effect on the ileal endogenous amino acid (AA) excretion in the growing pig. Maize starch and wood cellulose were selected as references. The inner fibrecontaining diet was also supplemented with enzymatically hydrolysed casein (EHC) in order to test the peptide alimentation method on a diet containing a fibre source with a high water-holding capacity (WHC = 10.9 g water g-' DM). The fibres were also analysed by different methods (crude fibre, NDF, ADF, enzymatic-gravimetric method, Englyst method). The fibre content of the inner fibre fraction varied widely from one method to another and ranged from 109 g crude fibre to 480 g AOAC fibre kg-' DM. Compared to the 'maize starch + wood cellulose' diet (11.0 g AA excreted kg-' DM intake), pea starch had no effect on ileal AA losses (9.6 g), whereas pea hulls slightly increased them (14.2 g). The AA excretion dramatically increased with the incorporation of inner fibres (28.0 g), because of their very high WHC. The addition of EHC increased the output (48.0 g) further, at a level that can hardly be explained only by an increase of the endogenous secretions. The results suggest that the NDF content of grain legume products is not indicative of their effect on the ileal endogenous AA losses in pigs and that the physiological effects of fibres along the gastrointestinal tract are due to both their chemical and physical properties. [less ▲]

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See detailModelling the North Sea hydrodynamics in a management perspective
Djenidi, Salim ULg; Delhez, Eric ULg; Martin, Géraldine ULg et al

in Bulletin de la Société Royale des Sciences de Liège (1996), 65

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See detailThe frequency of cutaneous vasculitis is not increased in patients with rheumatoid arthritis treated with methotrexate
Kaye, O.; Beckers, C. C.; Paquet, P. et al

in Journal of Rheumatology (1996), 23(2), 253-257

OBJECTIVE: To analyse the frequency, type, and immunohistological features of clinical cutaneous vasculitis developing in patients with rheumatoid arthritis (RA) treated or not with methotrexate as well ... [more ▼]

OBJECTIVE: To analyse the frequency, type, and immunohistological features of clinical cutaneous vasculitis developing in patients with rheumatoid arthritis (RA) treated or not with methotrexate as well as their demographic, clinical and biological characteristics. METHODS: Ninety-one patients with RA receiving 9.5 mg/wk of methotrexate (MTX) were compared for an average observation time of 18 months to 130 matched patients with RA treated with various drugs excluding MTX. RESULTS: Whether receiving MTX or not, 5.4% of patients with RA developed a clinical cutaneous vasculitis. There were significant differences between both groups for 2 variables only: a higher percentage of polyneuropathies and a higher level of immune complex-plasma levels in non-MTX patients. The immunohistological analysis did not differentiate both groups. CONCLUSION: The percentage of cutaneous vasculitis that developed under MTX therapy was not different from that occurring as a natural complication of longstanding severe RA. [less ▲]

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See detailBibliographie de Jean Haust
Boutier, Marie-Guy ULg

in Dialectes de Wallonie (1996), 23-24

Bibliographie de Jean Haust et index raisonné de l'ensemble de l'oeuvre.

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See detailPeritoneal endometriosis and "endometriotic" nodules of the rectovaginal septum are two different entities.
Donnez, Jacques; NISOLLE, Michelle ULg; Smoes, Pierre et al

in Fertility and Sterility (1996), 66(3), 362-8

OBJECTIVES: To compare histologically and stereologically the endometriotic nodule of the rectovaginal septum to peritoneal endometriosis. DESIGN: Morphometric investigation, cytokeratin and vimentin ... [more ▼]

OBJECTIVES: To compare histologically and stereologically the endometriotic nodule of the rectovaginal septum to peritoneal endometriosis. DESIGN: Morphometric investigation, cytokeratin and vimentin content, and steroid receptor evaluation were performed on endometriotic tissue from the peritoneum (n = 52) and rectovaginal nodules (n = 68). SETTING: An academic teaching hospital. PATIENTS: Biopsies were taken from 120 patients undergoing a laparoscopy for infertility and/ or pelvic pain (52 from typical black peritoneal endometriotic implants and 68 from endometriotic nodule of the rectovaginal septum). None of the patients were treated. RESULTS: Mitotic activity was found to be significantly different in peritoneal and rectovaginal endometriosis. The evaluation suggested that the stroma is not mandatory for the invasion of glandular epithelium in the rectovaginal nodule, which is, like a adenomyoma, a circumscribed nodular aggregate of smooth muscle and glandular elements. Cytokeratin and vimentin content as well as the estrogen receptor (ER) and P receptor (PR) content were significantly lower in both types of lesion when compared with eutopic endometrium. But vimentin immunoreactivity in epithelium, as well as the ER and PR content, were significantly lower in nodules when compared with black peritoneal lesions. CONCLUSION: It is suggested that the rectovaginal endometriotic nodule is a different disease from peritoneal endometriosis and must be called rectovaginal adenomyosis or rectovaginal adenomyoma. Its histopathogenesis probably is not related to the implantation of regurgitated endometrial cells but to the metaplasia of Müllerian rests. [less ▲]

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See detailRheumatic and musculoskeletal diseases and impaired quality of life. A challenge for rheumatologists
Morales-Torres, J; Reginster, Jean-Yves ULg; Hochberg, MC

in Journal of Rheumatology (1996), 23

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See detailModelling of repeated series of count data measured at unequally spaced times
Lambert, Philippe ULg

in Journal of the Royal Statistical Society : Series C (Applied Statistics) (1996), 45

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See detailAlteration of the endocrinological status of growing calves by a glucocorticoids treatment
Massart, Serge; Bertozzi, Carlo; Prandi, Alberto et al

in Journal of Animal Science (1996), 74(suppl 1), 230

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See detailCloning, sequencing and overexpression in Escherichia coli of the alginate lyase-encoding aly gene of Pseudomonas alginovora: identification of three classes of alginate lyases
Chavagnat, Frederic; Duez, Colette ULg; Guinand, Micheline et al

in Biochemical Journal (1996), 319(Pt 2), 575-583

A gene of Pseudomonas alginovora, called aly, has been cloned in Escherichia coli using a battery of PCR techniques and sequenced. It encodes a 210-amino-acid alginate lyase (EC 4.2.2.3), Aly, in the form ... [more ▼]

A gene of Pseudomonas alginovora, called aly, has been cloned in Escherichia coli using a battery of PCR techniques and sequenced. It encodes a 210-amino-acid alginate lyase (EC 4.2.2.3), Aly, in the form of a 233-amino-acid precursor. P. alginovora Aly has been overproduced in E. coli with a His-tag sequence fused at the C-terminal end under conditions in which the formation of inclusion bodies is avoided. His-tagged P. alginovora Aly has the same enzymic properties as the wild-type enzyme and has the specificity of a mannuronate lyase. It can be purified in a one-step procedure by affinity chromatography on Ni(2+)-nitriloacetate resin. The yield is of 5 mg of enzyme per litre of culture. The amplification factor is 12.5 compared with the level of production by wild-type P. alginovora. The six alginate lyases of known primary structure fall into three distinct classes, one of which comprises the pair P. alginovora Aly and Klebsiella pneumoniae Aly. [less ▲]

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See detailSeasonal temperature and salinity fields in the Mediterranean Sea: Climatological analyses of a historical data set
Brasseur, P.; Beckers, Jean-Marie ULg; Brankart, J. M. et al

in Deep-Sea Research Part I, Oceanographic Research Papers (1996), 43(2), 159-192

Climatological analyses of a historical data base have been carried out with the aim of reconstructing the three-dimensional temperature and salinity fields in the Mediterranean Sea. Seasonal and monthly ... [more ▼]

Climatological analyses of a historical data base have been carried out with the aim of reconstructing the three-dimensional temperature and salinity fields in the Mediterranean Sea. Seasonal and monthly distributions of hydrographic properties have been computed by a variational inverse method as an alternate to the standard Gandin (1969; Objective analysis of meterological fields, Israeli Program for Scientific Translation, Jerusalem) procedure. The spline solutions of the minimization problem are demonstrated to be numerically and theoretically equivalent to field estimates obtained by conventional objective analysis. The application of a finite-element technique allows analysis to be performed in the model space rather than in the observational space, which substantially improves the numerical efficiency of the procedure. The parameters of the scheme are adjusted according to the statistics of the climatological data. The results,realized as gridded data sets (horizontal resolution of 0.25 degrees), show some trends in seasonal variability affecting the properties of water masses. As expected, the upper layer is subject to a well-defined seasonal signal affecting both the temperature and salinity fields. Error maps, reflecting the degree of uncertainty in the analyses, have been systematically produced. The present work is conceived as a basic support to more advanced studies such as diagnostic calculations, initialization of dynamical models, assimilation of hydrological data into primitive equation models, or planning of experimental surveys. New versions of the climatological fields will be released as data are added to the historical data base. Copyright (C) 1996 Elsevier Science Ltd. [less ▲]

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See detailNew Devonian fossil localities in Bolivia
Blieck, A; Gagnier, PY; Bigey, FP et al

in Journal of South American Earth Sciences (1996), 9(5-6), 295--308

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See detail"Parce que je ne connais pas bien le grec..." (P. Col. Zen. II 66)
Rochette, Bruno ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1996), 71(142), 311-316

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See detailExpansive benign lesions: treatment by laser.
Smets, Mireille; NISOLLE, Michelle ULg; Bassil, Salim et al

in European Journal of Obstetrics and Gynecology (1996), 65(1), 101-5

Submucous fibroids, polyps and dysfunctional bleeding are responsible for meno-metrorrhagia in women over 40 years of age. The authors describe the technique of hysteroscopic myomectomy and endometrial ... [more ▼]

Submucous fibroids, polyps and dysfunctional bleeding are responsible for meno-metrorrhagia in women over 40 years of age. The authors describe the technique of hysteroscopic myomectomy and endometrial ablation using the Nd-YAG laser and the advantages of the preoperative use of GnRH agonist therapy. They report their results in a series of 746 patients treated for meno-metrorrhagia (366 cases of myomectomy and 380 cases of endometrial ablation). [less ▲]

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See detailEnergy levels and oscillator strengths for transitions in Pd II
Quinet, Pascal ULg

in Physica Scripta (1996), 54

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See detail"Le plus subtil ouvrir de monde" Godefroid de Huy,orfèvre mosan
George, Philippe ULg

in Cahiers de Civilisation Médiévale (1996), XXXIX

http://www.persee.fr/web/revues/home/prescript/article/ccmed_0007-9731_1996_num_39_156_2659

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See detailImprint and Brush Cytology in the Diagnosis of Canine Intranasal Tumours
Clercx, Cécile ULg; Wallon, J.; Gilbert, S. et al

in Journal of Small Animal Practice (1996), 37(9), 423-7

Fifty-four dogs with nasal tumours were included in this study. Based on histopathology 52 tumours were malignant (36 epithelial and 16 mesenchymal) and two were benign (one oncocytoma and one ... [more ▼]

Fifty-four dogs with nasal tumours were included in this study. Based on histopathology 52 tumours were malignant (36 epithelial and 16 mesenchymal) and two were benign (one oncocytoma and one pleiomorphic adenoma). Malignancy was significantly more frequently diagnosed by imprint cytology (81 per cent of the cases) than by brush cytology (56 per cent). Brush cytology was a significantly more sensitive technique in epithelial than in mesenchymal tumours, while the sensitivity of imprint cytology was not affected by the histological type. Brush cytology determined an epithelial origin in 88 per cent of epithelial tumours, and imprint cytology in 90 per cent. In mesenchymal tumours, the scores were significantly lower, the histological type being determined in only 20 per cent and 50 per cent, using brush and imprint cytology, respectively. [less ▲]

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See detailGuidelines for authors of medical scientific manuscripts.
Detry, Olivier ULg; Van Damme, Hendrik ULg; Van de Stadt, J.

in Acta Chirurgica Belgica (1996), 96(4), 140-3

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See detailInfluence of the production of two lipopeptides, Iturin A and Surfactin S1, on oxygen transfer during Bacillus subtilis fermentation
Hbid, Choukri; Jacques, Philippe; Razafindralambo, Hary ULg et al

in Applied Biochemistry and Biotechnology (1996), 57-8

Bacillus subtilis produces three types of lipopeptides: Iturins, Fengycins, and Surfactins. These amphiphilic molecules influence the volumetric oxygen transfer (K(L)a) like chemical surfactant. K(L)a ... [more ▼]

Bacillus subtilis produces three types of lipopeptides: Iturins, Fengycins, and Surfactins. These amphiphilic molecules influence the volumetric oxygen transfer (K(L)a) like chemical surfactant. K(L)a values were from two- to fivefold lower when both Iturin A and Surfactin S1 were coproduced, and from 0.57- to 0.8-fold lower when only Iturin A was produced. The addition of an oxygen vector (n-Dodecane) during fermentation increased K(L)a values (7.5-fold) and biomass production (twofold), and decreased Iturin A and Surfactin S1 production. However, at high stirring conditions and in the presence of n-Dodecane, Iturin A production was improved. [less ▲]

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See detailVers une perspective transactionnelle du stress au travail : pistes d'évaluations méthodologiques
De Keyser, Véronique ULg; Hansez, Isabelle ULg

in Cahiers de Médecine du Travail (1996), 33(3), 133-144

L'objectif principal de cet article est d'élaborer des pistes d'évaluations méthodologiques pour les études sur le stress au travail. L'approche se base sur une définition du stress axée sur le contrôle ... [more ▼]

L'objectif principal de cet article est d'élaborer des pistes d'évaluations méthodologiques pour les études sur le stress au travail. L'approche se base sur une définition du stress axée sur le contrôle de la situation et adopte une conception transactionnelle du stress psychologique au travail insistant sur l'importance de l'évaluation de la situation par l'individu et les processus de coping, dans une perspective diachronique (Mackay et Cooper, 1987). Cet article synthétise les indices utilisés généralement dans les recherches sur le stress au travail et discute leurs limites. Les problèmes méthodologiques envisagés sont les suivants: la difficulté d'établir des relations causales, les problèmes de validité discriminante et convergente, la mise en évidence des effets de chronicité, la fidélité des mesures. Des suggestions sont alors proposées, basées principalement sur une démarche combinant comparaisons intra et inter-individuelles, la méthode des «critical job events» ou approche épidémiologique, les stratégies de triangulation, le tout dans une perspective longitudinale. Pour terminer, des exemples en milieu hospitalier illustrent les démarches proposées. [less ▲]

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See detailOne-pot enzymatic synthesis of the Gal alpha 1-->3Gal beta 1-->4GlcNAc sequence with in situ UDP-Gal regeneration.
Hokke, Cornelis H; Zervosen, Astrid ULg; Elling, Lothar et al

in Glycoconjugate Journal (1996), 13(4), 687-92

The trisaccharide Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was enzymatically synthesized, with in situ UDP-Gal regeneration. By combination in one pot of only four enzymes, namely ... [more ▼]

The trisaccharide Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was enzymatically synthesized, with in situ UDP-Gal regeneration. By combination in one pot of only four enzymes, namely, sucrose synthase, UDP-Glc 4'-epimerase, UDP-Gal:GlcNAc beta 4-galactosyltransferase and UDP-Gal:Gal beta 1-->4GlcNAc alpha 3-galactosyltransferase, Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was formed in a 2.2 mumol ml-1 yield starting from the acceptor GlcNAc beta 1-->O-(CH2)8COOCH3. This is an efficient and convenient method for the synthesis of the Gal alpha 1-->3Gal beta 1-->4GlcNAc epitope which pays an important role in various biological and immunological processes. [less ▲]

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See detailA propos de la genèse des orthostates néo-assyriens
Tunca, Önhan ULg

in Tablettes et images aux pays de Sumer et d'Akkad. Mélanges offerts à Monsieur H. Limet (A.P.H.A.O. Mémoires n° 1) (1996)

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See detailYves Panafieu, Le mystère Buzzati, Liancourt-Saint-Pierre, Y. P., 1995, 303
Curreri, Luciano ULg

in Studi buzzatiani (1996), 1

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See detailDeposition in the Distal Parts of the Bovine Respiratory Tract: Assessment of Equipment Suitable for Drug Inhalation
Genicot, Bruno; Votion, Dominique ULg; Munsters, K. et al

in Veterinary Record : Journal of the British Veterinary Association (1996), 138(13), 302-304

The efficiency of equipment suitable for the inhalation of drugs by calves was assessed in six animals which inhaled radioisotopically labelled particles while suffering from reversible diffuse ... [more ▼]

The efficiency of equipment suitable for the inhalation of drugs by calves was assessed in six animals which inhaled radioisotopically labelled particles while suffering from reversible diffuse bronchoconstriction induced experimentally with 5-hydroxytryptamine and while they were breathing normally. Respiratory rates and data from pulmonary function tests and scintiscans were recorded during both investigations. After the first investigation, a mean (se) wash-out period of 9.8 (3.2) days was allowed. Under diffuse bronchoconstriction, the respiratory rate, the oscillatory resistance and the compliance of the respiratory system reached 282.1 (22.0), 161.1 (10.8) and 68.8 (2.7) per cent of their respective baseline values. When the calves were breathing normally these parameters did not change over time. The ratios (Cp/Ct) of the counts of gamma-disintegrations in the peripheral part (Cp) of the lungs and in the total lung area (Ct) were not significantly different when comparing the results from the two investigations. The ratios of Cp/Ct in the left lungs did not differ significantly from those in the right lungs. [less ▲]

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See detailA Novel Oxidizing Reagent Based on Potassium Ferrate(VI)
Delaude, Lionel ULg; Laszlo, Pierre ULg

in Journal of Organic Chemistry (1996), 61(18), 6360-6370

A new, efficient preparation has been devised for potassium ferrate(VI) (K(2)FeO(4)). The ability of this high-valent iron salt for oxidizing organic substrates in nonaqueous media was studied. Using ... [more ▼]

A new, efficient preparation has been devised for potassium ferrate(VI) (K(2)FeO(4)). The ability of this high-valent iron salt for oxidizing organic substrates in nonaqueous media was studied. Using benzyl alcohol as a model, the catalytic activity of a wide range of microporous adsorbents was ascertained. Among numerous solid supports of the aluminosilicate type, the K10 montmorillonite clay was found to be best at achieving quantitative formation of benzaldehyde, without any overoxidation to benzoic acid. The roles of the various parameters (reaction time and temperature, nature of the solvent, method of preparation of the solid reagent) were investigated. The evidence points to a polar reaction mechanism. The ensuing procedure was applied successfully, at room temperature, to oxidation of a series of alcohols to aldehydes and ketones, to oxidative coupling of thiols to disulfides, and to oxidation of nitrogen derivatives. At 75 degrees C, the reagent has the capability of oxidizing both activated and nonactivated hydrocarbons. Toluene is turned into benzyl alcohol (and benzaldehyde). Cycloalkanes are also oxidized, in significant (30-40%) yields, to the respective cycloalkanols (and cycloalkanones). Thus, potassium ferrate, used in conjunction with an appropriate heterogeneous catalyst, is a strong and environmentally friendly oxidant. [less ▲]

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See detailImages liées à la pathologie traumatique du système nerveux central
Leroy, Patricia; Dubru, Jean-Marie ULg; Misson, Jean-Paul ULg

in Acta Paediatrica Belgica (1996), 28(3), 216

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See detailVoltage stability analysis in transient and mid-term time scales
Van Cutsem, Thierry ULg; Vournas, Costas

in IEEE Transactions on Power Systems (1996), 11

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See detailLe cas clinique du mois : syndrome de Moskowitz chez un patient traité par ticlopidine
FRANCHIMONT, D; Freres, Pierre ULg; LEBRUN, F et al

in Revue Médicale de Liège (1996), 51(3), 214-216

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See detailLes reliques sur ordinateur
George, Philippe ULg

in Le médiéviste et l'ordinateur (1996)

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See detailLes infections utérines dans l’espèce bovine: 1. Aspects étiologiques et épidémiologiques
Hanzen, Christian ULg; Houtain, J. Y.; Laurent, Y.

in Point Vétérinaire (1996), 28(numéro spécial), 1013-1017

Assessing the frequency of metritis shows the animal uterine health as well as the herd . The practitioner prefers to use vaginal examination. The great diversity and variation postpartum in germs ... [more ▼]

Assessing the frequency of metritis shows the animal uterine health as well as the herd . The practitioner prefers to use vaginal examination. The great diversity and variation postpartum in germs responsible for uterine diseases make it difficult to interpret bacteriology. Uterine diseases are all the more frequent as the interval between calving and clinical examination is shorter, therefore the practitioner screening needs to be done as soon as possible. This recommendation is valid for the primiparous dairy cow as well as the suckler cow [less ▲]

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See detailA Non-Cofactor Role of Thiamine Derivatives in Excitable Cells?
Bettendorff, Lucien ULg

in Archives of Physiology & Biochemistry (1996), 104(6), 745-751

Thiamine diphosphate (TDP) is an important cofactor of pyruvate (PDH) and alpha-ketoglutarate (KGDH) dehydrogenases and transketolase. Thiamine deficiency leads to reversible and irreversible brain ... [more ▼]

Thiamine diphosphate (TDP) is an important cofactor of pyruvate (PDH) and alpha-ketoglutarate (KGDH) dehydrogenases and transketolase. Thiamine deficiency leads to reversible and irreversible brain lesions due to impaired oxidative metabolism. A specific non-cofactor role for thiamine has also been proposed in excitable cells and thiamine triphosphate (TTP) might be involved in the regulation of ion channels. Thiamine is taken up by neuroblastoma cells through a high affinity transporter. Inside the cells, it is rapidly phosphorylated to TDP. This high turnover TDP pool is the precursor for TTP. Most of the TDP however has a low turnover and is associated with PDH and KGDH in mitochondria. In excised inside-out patches from neuroblastoma cells, TTP, at a concentration of 1 microM, activates chloride channels of large unitary conductance, the so-called maxi-Cl- channels. These channels are inhibited by oxythiamine from the outide. In addition to the role of TTP in the regulation of chloride channels, thiamine itself, or a presently unknown analog, may have trophic effects on neuronal cells. [less ▲]

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See detailGlacial-interglacial variability of atmospheric CO2 due to changing continental silicate rock weathering: A model study
Munhoven, Guy ULg; Francois, Louis ULg

in Journal of Geophysical Research (1996), 101(D16), 21423-21437

An 11-box model of the oceanic carbon cycle including sedimentary processes is used to explore the role chemical weathering of continental silicate rocks might play in driving atmospheric CO2 levels on ... [more ▼]

An 11-box model of the oceanic carbon cycle including sedimentary processes is used to explore the role chemical weathering of continental silicate rocks might play in driving atmospheric CO2 levels on glacial-interglacial timescales. Histories for the consumption of CO2 by silicate rock weathering processes are derived from the marine Ge/Si record. Taking the major uncertainties in the knowledge of the Ge and Si cycles into account, several histories for the evolution of the riverine dissolved silica fluxes are calculated from this record. The investigation of the systematics between riverine dissolved silica and bicarbonate fluxes under different weathering regimes leads us to the tentative conclusion that although there is no correlation between dissolved silica and total bicarbonate concentrations in the major rivers, there may exist a negative correlation between weathering intensity and the ratio of dissolved silica to bicarbonate derived from silicate weathering alone. With this correlation as a working hypothesis, it is possible to interpret the dissolved silica fluxes in terms of equivalent CO2 consumption rates. The calculated histories indicate that glacial rates of CO2 consumption by chemical silicate rock weathering could have been twice, and possibly up to 3.5 times, as high as they are today. When used to force the carbon cycle model, they are responsible for glacial-interglacial pCO2 variations in the atmosphere of typically 50–60 ppm and up to 95–110 ppm. These variations are superimposed to a basic oscillation of 60 ppm generated by the model, mainly in response to coral reef buildup and erosion processes. The total pCO2 signal has an amplitude of about 80–90 ppm and up to 125–135 ppm. Although these large amplitudes indicate that silicate weathering processes should be taken into account when studying glacial-interglacial changes of CO2 in the atmosphere, it also raises new problems, such as too high CO2 levels during the period from 110–70 kyr B.P., requiring further study. [less ▲]

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See detailIsolation of nucleoli from ELT cells: a quick new method that preserves morphological integrity and high transcriptional activity.
Vandelaer, M.; Thiry, Marc ULg; Goessens, Guy ULg

in Experimental Cell Research (1996), 228(1), 125-31

We have developed a quick new method for isolating nucleoli which, unlike the methods in current use, preserves the nucleolar ultrastructure. Until now, the isolation process has generally been assumed to ... [more ▼]

We have developed a quick new method for isolating nucleoli which, unlike the methods in current use, preserves the nucleolar ultrastructure. Until now, the isolation process has generally been assumed to empty one of the three major compartments of the nucleolus, the fibrillar center, of its content. We have used the AgNOR staining and in vitro transcription assay to test the degree of structural and functional preservation of the isolated nucleoli. Our results demonstrate the value of our procedure as a reliable tool for biochemical and ultrastructural studies on the nucleolus. Moreover, these proprieties prompt us to investigate the rRNA synthesis, using a nonisotopic approach, within morphologically intact isolated nucleoli. Thus, we show that newly synthesized rRNA transcripts are located not only in the dense fibrillar component, but also indubitably in the fibrillar center. [less ▲]

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See detailAbsolute configuration of (R)-1-phenylethyl ammonium (S)-2-(6-methoxy-2-naphthyl)-propionate
Dupont, L.; Pirotte, Bernard ULg; De Tullio, Pascal ULg et al

in Acta Crystallographica (1996), C52

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See detailPistoi Hermeneis. La traduction orale en Grèce
Rochette, Bruno ULg

in Revues des Etudes grecques (1996), 109(2), 325-347

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See detailFoaming Properties Of Surfactin, A Lipopeptide Biosurfactant From Bacillus Subtilis
Razafindralambo, Hary ULg; Paquot, Michel ULg; Baniel, Alain et al

in Journal of the American Oil Chemists' Society (1996), 73(1), 149-151

Foaming properties of surfactin were investigated and compared to those of sodium dodecyl sulfate (SDS) and bovine serum albumin (BSA). Foams were formed by a bubbling technique. Evolution of the foam ... [more ▼]

Foaming properties of surfactin were investigated and compared to those of sodium dodecyl sulfate (SDS) and bovine serum albumin (BSA). Foams were formed by a bubbling technique. Evolution of the foam volume and the liquid in the foam was monitored with optical and conductimetric methods to characterize foam formation and stability. Excellent foaming properties of surfactin were shown by its higher ability to form and stabilize the foam at a concentration as low as 0.05 mg/mL, in comparison with SDS and BSA. Surfactin produced a foam with intermediate maximum density and stabilized the liquid in foam, as well as BSA. [less ▲]

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See detailFirst synthesis of 4-substituted benzenesulfonylcyanoguanidines
Masereel, B.; Lebrun, P.; Dogne, J.-M. et al

in Tetrahedron Letters (1996), 37

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See detailLigniculture et maintien de la fertilité des sols dans l'Ouest-Cameroun
Njoukam, Raphaël; Bock, Laurent ULg; Hebert, Jacques ULg et al

in Bois et Forêts des Tropiques (1996), (249), 33-49

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See detailQuestions de regards
Havelange, Carl ULg

in Le Carnet et les Instants (1996), septembre-novembre 1996(n° 94), 57

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See detailStructure and bonding in liquid tellurium
Bichara, C.; Raty, Jean-Yves ULg; Gaspard, Jean-Pierre ULg

in Physical Review. B, Condensed Matter and Materials Physics (1996), 53(1), 206-211211

The atomic structure and bonding mechanism in liquid tellurium have been investigated by a tight-binding Monte Carlo simulation. On melting, the chain structure of the crystal is preserved in spite of ... [more ▼]

The atomic structure and bonding mechanism in liquid tellurium have been investigated by a tight-binding Monte Carlo simulation. On melting, the chain structure of the crystal is preserved in spite of some significant changes in the local atomic environment. A third covalent bond appears with a bond length (widely distributed around 3.15 Aring) intermediate between those characteristic of the crystal. A short-long alternation of the bonds takes place within the chains, in agreement with the most recent extended X-ray-absorption fine structure measurements. In addition, the bond angle within the chains is reduced. Our calculations clearly prove that these effects are due to the electronic interaction between the lone pair orbitals. The subsequent broadening of the lone pair band is responsible for the semiconductor to metal transition that takes place upon melting. [less ▲]

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See detailActivation of ATP-dependant K+ channels and inhibition of insulin release: effect of BPDZ 62
Lebrun, P.; Antoine, M.-H.; Ouedraogo, R. et al

in Journal of Pharmacology and Experimental Therapeutics (The) (1996), 277

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See detailLes infections utérines dans l’espèce bovine : 2. Thérapeutiques anti-infectieuses et hormonales
Hanzen, Christian ULg; Houtain, J. Y.; Laurent, Y.

in Point Vétérinaire (1996), 28(numéro spécial), 1019-1025

The choice of an antibiotic or antiseptic treatment must take into account, the administrative route, the individual factors (nature of symptoms, stage postpartum, stage in the cycle) and the agents used ... [more ▼]

The choice of an antibiotic or antiseptic treatment must take into account, the administrative route, the individual factors (nature of symptoms, stage postpartum, stage in the cycle) and the agents used (nature of germs, minimal inhibiting concentration, pharmacological properties, milk residue). Hormonal treatment is an interesting alternative, which must be considered on an individual basis rather than systematically at herd level. For prevention, it should only be used on animals presenting a high risk factor of infection [less ▲]

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See detailEffect of some organophosphate insecticides on acetylcholinesterase of adult Coccinella septempunctata (Coccinellidae)
Bozsik, Andras; Haubruge, Eric ULg; Gaspar, Charles

in Journal of Environmental Science & Health. Part. B, Pesticides, Food Contaminants, & Agricultural Wastes (1996)

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See detailEffects of exogenous IL-1 beta, TNF alpha, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes.
Henrotin, Yves ULg; De Groote, D. D.; Labasse, A. H. et al

in Osteoarthritis and Cartilage (1996), 4(3), 163-73

Cytokines are potent regulators of the chondrocyte functions. Some of them are produced by chondrocytes and interact to regulate cartilage metabolism. In this study, we investigated the production of ... [more ▼]

Cytokines are potent regulators of the chondrocyte functions. Some of them are produced by chondrocytes and interact to regulate cartilage metabolism. In this study, we investigated the production of interleukin-1 beta (IL-1 beta), IL-6, IL-8 and leukemia inhibitory factor (LIF) by human chondrocytes and examined the modulation of their secretion by exogenous cytokines. Human articular chondrocytes were isolated from their extracellular matrix by a triple successive enzymatic digestion of the cartilage. Subsequently, chondrocytes were stimulated by increased amounts of human recombinant cytokines [IL-1 beta, tumour necrosis factor alpha (TNF alpha), IL-8, LIF, IL-6]. IL-1 beta, IL-6, IL-8 and LIF were assayed into culture media and inside cell extracts by specific enzyme amplified sensitivity immunoassays (EASIAs). Under these experimental conditions, we have identified various interactions between cytokines. IL-beta and TNF alpha highly stimulated IL-6, LIF and IL-8 productions. IL-6 decreased IL-8 synthesis and increased LIF production. IL-8 slightly enhanced IL-6 production. Finally, LIF stimulated IL-1 beta, IL-6 and IL-8 productions. Using neutralizing antibodies against IL-1, we demonstrated that the effects of LIF were secondary to the stimulation by LIF of IL-1 beta production by the chondrocytes. In conclusion, chondrocytes secrete a variety of immunocompetent cytokines including IL-1 beta, IL-6, IL-8 and LIF that can interact to regulate chondrocytes metabolism. These results also define new biological activities of LIF and IL-6, and raise questions concerning their role in the pathogenesis of joint diseases. [less ▲]

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See detail"Vielen Dank und auf Wiedersehen" : Mitteilungen an das Publikum in den Kinoprogrammen der Frühzeit
Belloi, Livio ULg

in KINtop : Jahrbuch zur Erforschung des frühen Films (1996), 5

Etude des vues d'annonce au public telles que la firme Lumière en a très tôt l'intuition, mais qui se développent surtout à partir de 1906, en conjonction avec l'émergence progressive des salles fixes et ... [more ▼]

Etude des vues d'annonce au public telles que la firme Lumière en a très tôt l'intuition, mais qui se développent surtout à partir de 1906, en conjonction avec l'émergence progressive des salles fixes et spécialisées, c'est-à-dire en même temps que l'apparition de cette instance historiquement constituée qu'est le spectateur de cinéma. [less ▲]

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See detailUna Cabeza Bien Hecha O Una Cabeza Repleta ?
Crahay, Marcel ULg

in Perspectivas (1996), XXVI(1),

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See detailHeparin-binding domain, type 1 and type 2 repeats of thrombospondin mediate its interaction with human breast cancer cells.
Incardona, F.; Lawler, J.; Cataldo, Didier ULg et al

in Journal of Cellular Biochemistry (1996), 62(4), 431-42

Thrombospondin is an adhesive glycoprotein that promotes breast cancer cell adhesion to human vascular endothelial cells (Incardona et al., 1995). In this study, we have identified the molecular domains ... [more ▼]

Thrombospondin is an adhesive glycoprotein that promotes breast cancer cell adhesion to human vascular endothelial cells (Incardona et al., 1995). In this study, we have identified the molecular domains of thrombospondin that mediate its binding to specific receptors on the human breast adenocarcinoma cell line, MDA-MB-231. Two recombinant fragments from the amino-terminus (TSPN18 and TSPN28), and the fusion proteins of the type 1 and type 2 repeats of human thrombospondin, inhibited binding of radiolabeled thrombospondin to MDA-MB-231 cells in suspension by 40-60% at 50 micrograms/ml whereas the type 3 repeat, carboxy-terminus and unfused glutathione-S-transferase as well as the synthetic peptide Gly-Arg-Gly-Asp-Ser (500 micrograms/ml) had little or no effect. Heparin and various glycosaminoglycans as heparan sulfate, chondroitin sulfates A, B or C, and fucoidan inhibited thrombospondin binding to MDA-MB-231 cells by more than 60% whereas dextran sulfate had only little effect. Treatment of cells with heparitinase, chondroitinase ABC, and hyaluronidase, but not with neuraminidase, induced 30-50% inhibition of thrombospondin binding suggesting the participation of both heparan sulfate and chondroitin sulfate cell surface-associated molecules. Inhibition of proteoglycan sulfation by chlorate or inhibition of glycosaminoglycan chain formation by two beta-D-xylosides also led to a substantial inhibition of thrombospondin binding. Our results indicate that several domains within the thrombospondin molecule, namely the amino-terminus, type 1 and type 2 repeats, participate in its binding to specific receptors bearing sulfated glycosaminoglycans on MDA-MB-231 cells. Biological assays have indicated that, in addition to these domains, the peptide Gly-Arg-Gly-Asp-Ser inhibited MDA-MB-231 cell attachment to thrombospondin suggesting that the last type 3 repeat of the molecule may also contribute to its cell adhesive activity. [less ▲]

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See detailOn the helminthofauna of wild mammals (Rodentia, Insectivora ans Lagomorpha) in Azores archipelago (Portugal)
Casanova, J. C.; Miquel, Jordi; Fons, Roger et al

in Vie et milieu (1996), 46(3-4), 253-259

The faunistic and ecological study of the helminthfaunas of mammals in Azorean islands is considered. 103 rodents (Rattus rattus L., 1758 and Mus musculus L., 1758) 9 insectivores (Erinaceus europaeus L ... [more ▼]

The faunistic and ecological study of the helminthfaunas of mammals in Azorean islands is considered. 103 rodents (Rattus rattus L., 1758 and Mus musculus L., 1758) 9 insectivores (Erinaceus europaeus L., 1758) and 19 lagomorphs (Oryctolagus cuniculus L., 1758) were analysed. The hosts been captured in several biotopes of thre islands (São Miguel, Terceira and Flores). 27 helminth species were detected (3 Digenea Trematoda, 5 Cestoda, 18 Nematoda and 1 Acantocephala). All hosts species show high prevalences and no significant differences were found between different islands. The helminthfaunas show typical features of a young island parasitofaunas. [less ▲]

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See detailDesign and modeling of new platelet-activating factor antagonists.2. Synthesis and biological activity of 1,4-bis-(3',4',5'-trimethoxybenzoyl)-2-alkyl and 2-alkoxymethylpiperazines
Tavet, Fabrice; Lamouri, Aazdine; Heymans, Françoise et al

in Journal of Lipid Mediators and Cell Signalling (1996), 15

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See detailChanges in gene expression in the leaf of Lolium temulentum L. Ceres during the photoperiodic induction of flowering
Périlleux, Claire ULg; Ongena, Philippe; Bernier, Georges ULg

in Planta (1996), 200(1), 32-40

Unifoliated plants of Lolium temulentum L. Ceres were induced to flower by a unique 24-h long day (LD) consisting of the extension of the regular 8-h short day (SD) (400 µmol photons·m-2·s-1, fluorescence ... [more ▼]

Unifoliated plants of Lolium temulentum L. Ceres were induced to flower by a unique 24-h long day (LD) consisting of the extension of the regular 8-h short day (SD) (400 µmol photons·m-2·s-1, fluorescence + incandescence) with incandescence at 10–15 µmol photonsm -2·s-1. The polyadenylated-RNA complement of leaf blade tissues was analysed at 4-h intervals during the photoperiod extension in LD vs. SD, by using two-dimensional polyacrylamide gel electrophoresis to resolve in-vitro-translated products. Of the 991 spots that were analysed, none appeared or disappeared during the inductive cycle, i.e. no qualitative effect of floral induction was detected, at any time. Sixty-eight spots were found whose intensity was influenced by lengthening of the photoperiod; 50 of them, i.e. ca. 5 of the population analysed, were affected before the end of the extension period and were thus potentially related to floral induction. Many of these RNAs were not quantitatively constant during a 24-h cycle in SD. Seven of them oscillated according to the ‘light-on’ and the ‘light-off’ signals, among which three seemed to be controlled by phytochrome since their relative amount increased under the standard light conditions but decreased under incandescence even faster than in darkness. The large majority of other RNAs varied with a timing that was not clearly driven by the alternation of light and darkness, indicating that genes related to the biological clock may be especially sensitive to the lengthening of the photoperiod. Furthermore, seven spots were observed that underwent a phase-shift in LD, which consisted, for six of them, of a phase advance of 4–8 h. The steady-state level of CAB mRNA was analysed because the CAB gene family (encoding the chlorophyll a/b-binding proteins of the light-harvesting complexes) is known to be controlled both by the biological clock and phytochrome. In SD, the level was high in the light and low in darkness; the fluctuation was conducted by a circadian rhythm. When plants were exposed to the inductive LD, the peak of mRNA accumulation that was expected according to the endogenous rhythmicity was abolished, possibly because of the change in light quality during the LD extension. [less ▲]

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See detailIpriflavone in prevention and treatment of postmenopausal and senile osteoporosis
Reginster, Jean-Yves ULg

in Osteoporosis News (1996), 4

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