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See detailTYPE OF WEAR FOR THE PAIR TI6A14V/PCTFE IN AMBIENT AIR AND IN LIQUID-NITROGEN
Bozet, Jean-Luc ULg

in Wear (1993), 162(Part B), 1025-1028

In the development of large, high pressure valves for cryotechnic rocket engines, the Tribology Department of the University of Liege had the opportunity to evaluate the pair Ti6Al4V ... [more ▼]

In the development of large, high pressure valves for cryotechnic rocket engines, the Tribology Department of the University of Liege had the opportunity to evaluate the pair Ti6Al4V/polychlorotrifluoroethylene (PCTFE) on a pin-on-disk tribometer in ambient air and liquid nitrogen with the contact pressure and sliding speed ranging, respectively, from 3 to 9 MPa and 0.03 to 0.05 m s-1. Because of the affinity of titanium for halogen elements, such as chlorine and fluorine, which are both present in PCTFE, we noticed the formation of an abrasive compound made of chlorine, fluorine, titanium and aluminium. These elements were detected by electron microscopy. In both environments the heat produced during sliding is responsible for the decomposition of the PCTFE. The surface of the polymer is softened by the heat and embedded abrasive particles then scratch the sliding track of the Ti6Al4V disk. This abrasiveness is confirmed with a three-dimensional stylus profilometer used on the Ti6Al4V disks. The low temperature and neutrality of liquid nitrogen hardly inhibit the decomposition of the polymer. This is related to the poor thermal conductivity of both titanium and PCTFE: the heat produced at the contact is fully available for the chemical reaction between the chlorine, fluorine and titanium, all the more so since this reaction requires little energy to take place. A better understanding of the wear behaviour of the pair PCTFE/Ti6Al4V in both air and liquid nitrogen should lead to the development of a surface treatment which prevents the formation of abrasive particles. We could then use titanium alloys as bulk materials for sliding parts in cryogenic valves and, because of the low specific mass of titanium, could benefit from the subsequent weight reduction. [less ▲]

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See detailMicroclimat et composition de l'air dans une enceinte fermée destinée à l'étude de la toxicité des polluants atmosphériques chez le porcelet
Urbain, B.; Gustin, Pascal ULg; Prouvost, J. F. et al

in Veterinary Research (1993), 24(6), 503-514

An experimental model representing the pollution background in a pigpen was constructed in order to study the toxicology of pig respiratory air pollutants. Temperature, relative humidity, air-flow rate ... [more ▼]

An experimental model representing the pollution background in a pigpen was constructed in order to study the toxicology of pig respiratory air pollutants. Temperature, relative humidity, air-flow rate, total dust, total viable particles, endotoxins in respirable dust (< 5 microns) and ammonia were measured in a 1.9 m3 environmental chamber designed for piglets. The activity of 1 piglet was recorded on video. Temperature and relative humidity were respectively 23.9 +/- 1.3 degrees C and 70.5 +/- 8.3% (mean +/- SD). Air flow rate was 10 m3/h. Dust, viable particles, endotoxin and ammonia concentrations were respectively 7 +/- 2 particles/ml, 3.4 x 10(4) +/- 2.9 x 10(4) BCFP (bacterial colony-forming particles)/m3, 4.8 +/- 1.5 ng/m3 and 6 +/- 0.8 ppm (mean +/- SD). All these parameters were comparable to the lowest values recorded in pigpens [less ▲]

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See detailLocation of the rRNA gene
Thiry, Marc ULg

in Rice Biotechnology Quarterly (1993), 15

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See detailMourir à son postmoderne
Demoulin, Laurent ULg

in Ecritures (1993), 5

Treize réflexions sur la notion de postmodernité, considérée étymologiquement, c'est-à-dire comme un "après" la modernité (et non comme un retour en arrière, ou une surmodernité). La postmodernité est à ... [more ▼]

Treize réflexions sur la notion de postmodernité, considérée étymologiquement, c'est-à-dire comme un "après" la modernité (et non comme un retour en arrière, ou une surmodernité). La postmodernité est à distinguer du postmodernisme (si celui-ci existe). [less ▲]

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See detailThree-dimensional General Circulation Model of the Northern Bering Sea’s Summer Ecohydrodynamics
Nihoul, Jacques ULg; Adam, Paul; Brasseur, Pierre et al

in Continental Shelf Research (1993), 13(5-6), 509-542

The main features of the northern Bering Sea's summer ecohydrodynamics are investigated with the help of two three-dimensional—direct and inverse—models developed at theGeoHydrodynamics ... [more ▼]

The main features of the northern Bering Sea's summer ecohydrodynamics are investigated with the help of two three-dimensional—direct and inverse—models developed at theGeoHydrodynamics andEnvironmentResearch Laboratory of the University of Liège (GHER). Each model consists of two interacting sectorial submodels for (i) the general circulation hydrodynamics and synoptic structures, and (ii) the associated plankton ecosystem dynamics. The direct model is used to simulate, from an initial state compatible with historical, climatological and all available data pertinent to the summer season, a typical overview of the northern Bering Sea's ecohydrodynamics during the summer. The inverse model is applied in a two-fold perspective: (i) the reconstruction of typical summer distributions of temperature and salinity by using more than 1500 CTD profiles measured during the months of July, August and September, in the course of the ISHTAR program; (ii) considering the observations from specific ISHTAR surveys as quasi-synoptic, the reconstruction of individual data fields in order to provide additional information to assess the variability of the system. The model's predictions indicate that the summer dynamics are dominated by a few cogent semi-permanent and reproducible mechanisms which govern the main water mass transports, the upwellings, the fronts and the subsequent seasonal patterns of primary and secondary productions. The general circulation fields calculated by the direct model are considered as a standard of reference to give a coherent interpretation of—local and often instantaneous—observations, process studies and related results, in the context of the natural variability of the system. The simulated flow pattern has been validated, using the set of current measurements provided by 1985 and 1986 ISHTAR moorings. The contribution of the Anadyr Stream to the northward transport is reproduced qualitatively and quantitatively. The vertical motions—undetectable from direct experiments—are computed by the model, and represent one of the most efficient constraints on the ecohydrodynamics. For instance, the strong upwelling located along the Siberian coast—the existence of which was only presumed until recently—is now correctly estimated in position and intensity. The exceptionally high concentrations of nutrients found in the upwelled water turn this hydrodynamic structure into a catalyst element for the development of biological species in the region. The pattern of primary production shows two successive maxima: the first appears as a direct consequence of the frontal conditions associated with the Anadyr Stream, whereas the second develops further north, in the Chukchi Sea. The results display a fairly good agreement with the classical descriptions induced from observations, and suggest that the advection-growth coupling is the main physical conditioning factor for biological processes. [less ▲]

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See detailThe fractal nature of the power spectrum as an indicator of chaos in the Bianchi-IX cosmological model
Demaret, Jacques; De Rop, Yves ULg

in Physics Letters B (1993), 299(3-4), 223-228

Using two different methods, we compute the fractal dimension of the power spectrum associated with numerical solutions of the spatially homogeneous Bianchi IX cosmological model in Misner-Chitre ... [more ▼]

Using two different methods, we compute the fractal dimension of the power spectrum associated with numerical solutions of the spatially homogeneous Bianchi IX cosmological model in Misner-Chitre coordinates. According to Perdang's criterion, the noninteger character of this dimension is reflection of chaos and can be used to measure it, in the same spirit as the Lyapunov exponent of the Kolmogorov entropy. The results obtained indicate the chaotic nature of the behaviour of the Bianchi IX model near the cosmological singularity. [less ▲]

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See detailIn Vivo Free Radical Production after Cross-Clamping and Reperfusion of the Renal Artery in the Rabbit
DEFRAIGNE, Jean ULg; PINCEMAIL, Joël ULg; FRANSSEN, Colette ULg et al

in Cardiovascular Surgery (1993), 1(4), 343-9

Postischaemic reperfusion injury is often attributed to the generation of oxygenated free radicals which may subsequently promote lipid peroxidation in cell membranes. Electron paramagnetic resonance ... [more ▼]

Postischaemic reperfusion injury is often attributed to the generation of oxygenated free radicals which may subsequently promote lipid peroxidation in cell membranes. Electron paramagnetic resonance spectroscopy in association with the spin trap molecule alpha-phenyl-N-tert-butyl-nitrone allowed direct confirmation of lipid free radical production after renal ischaemia-reperfusion in an in vivo rabbit model. A 60-min period of ischaemia followed by reperfusion caused free radical production twofold greater than after 15 min of ischaemia. Glutathione and alpha-tocopherol have been measured in renal tissue, as indirect markers of lipid peroxidation. After 15 min of ischaemia followed by 10 min of reperfusion, the mean(s.e.m.) glutathione content of the ischaemic kidney was slightly but significantly reduced by 11.9(2.5)% (P < 0.003). The content of alpha-tocopherol was unchanged. However, 10 min of reperfusion following 60 min of ischaemia led to significant decrease in mean(s.e.m.) content of both glutathione (30.4(3.7)%) (2.23(0.2) versus 3.14(0.18) mumol/g wet tissue, P < 0.001) and alpha-tocopherol (46.1(7.8)%) (0.57(0.10) versus 1.09(0.14) micrograms/g wet tissue, P < 0.001) when compared to the control kidney. Under these experimental conditions, desferrioxamine (15 mg/kg administered intravenously before inducing ischaemia), a drug known to limit free radical production, significantly limited the decrease of alpha-tocopherol to 20.8(6.4)% (0.83(0.08) versus 1.05(0.04) micrograms/g wet tissue, P < 0.05), but did not prevent glutathione consumption in the reperfused kidney. [less ▲]

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See detailHistoplasmose africiaine à Histoplasma duboisii (Histoplasma capsulatum var. duboisii): quatorze cas congolais observés en 10 ans (1981-1990)
Carme, Bernard; Hayette, Marie-Pierre ULg; Itoua Ngaporo, A. et al

in Journal de Mycologie Médicale (1993), 3

Fourteen cases of histoplasmosis due to Histoplasma duboisii seen in Congo from 1981 through 1990, are reported: the average age of the patients was 25 years (the youngest being 1,5 y and the oldest 50y ... [more ▼]

Fourteen cases of histoplasmosis due to Histoplasma duboisii seen in Congo from 1981 through 1990, are reported: the average age of the patients was 25 years (the youngest being 1,5 y and the oldest 50y), the M/F ratio was 2,5; most of the patients (10/14) live in a rural area. there was a rather constant frequency of one to three cases per annum from 1981 through 1990. The fisrt congolese AIDS-associated systemic histoplasmosis duboisii case was observed in 1990. Lymph node involvment and mucocutaneous lesions were the most frequent clinical manifestations. In all cases, the disgnosis was established by histological examination. When performed, direct microscopy was always positive (11/11). Isolation of H. duboisii in culture was successful in 7 out of 9 attempts. Two cases of systemic infection were rapidly fatal but a good clinical response was obtained in the other cases wih amphotericin B, which due to intolerance, was replaced by ketoconazole in 2 patients. [less ▲]

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See detailLes aquifères crayeux en Belgique
Dassargues, Alain ULg; Monjoie, Albéric ULg

in Hydrogéologie (1993), (2), 135-145

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See detailTransforming growth factor ß as a neuronoglial signal during peripheral nervous sytem response to injury.
Rogister, Bernard ULg; Delrée, P.; Leprince, Pierre ULg et al

in Journal of Neuroscience Research (1993), 34

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See detailOlfactory receptors are displayed on dog mature sperm cells
Vanderhaeghen, P.; Schurmans, Stéphane ULg; Vassart, G. et al

in Journal of Cell Biology (1993), 123

Olfactory receptors constitute a huge family of structurally related G protein-coupled receptors, with up to a thousand members expected. We have shown previously that genes belonging to this family were ... [more ▼]

Olfactory receptors constitute a huge family of structurally related G protein-coupled receptors, with up to a thousand members expected. We have shown previously that genes belonging to this family were expressed in the male germ line from both dog and human. The functional significance of this unexpected site of expression was further investigated in the present study. We demonstrate that a few dog genes representative of various subfamilies of olfactory receptors are expressed essentially in testis, with little or no expression in olfactory mucosa. Other randomly selected members of the family show the expected site of expression, restricted to the olfactory system. Antibodies were generated against the deduced amino acid sequence of the most abundantly expressed olfactory receptor gene in dog testis. The purified serum was able to detect the gene product (DTMT receptor) in late round and elongated spermatids, as well as in the cytoplasmic droplet that characterizes the maturation of dog sperm cells, and on the tail midpiece of mature spermatozoa. Western blotting further confirmed the presence of a 40-kD immunoreactive protein in the membrane of mature sperm cells. Altogether , these results demonstrate that the main expression site of a subset of the large olfactory receptor gene family is not olfactory mucosa but testis. This expression correlates with the presence of the corresponding protein during sperm cell maturation, and on mature sperm cells. The pattern of expression is consistent with a role as sensor for unidentified chemicals possibly involved in the control of mammalian sperm maturation, migration, and/or fertilization [less ▲]

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See detailCommon stochastic trends in European stock markets
Corhay, Albert ULg; Tourani-Rad, Alireza; Urbain, Jean-Pierre ULg

in Economics Letters (1993), 42(4), 385-390

The objective of the paper is to investigate whether price indices of different European stock markets display a common long-run trending behaviour. Using cointegration analysis, we provide empirical ... [more ▼]

The objective of the paper is to investigate whether price indices of different European stock markets display a common long-run trending behaviour. Using cointegration analysis, we provide empirical evidence of common stochastic trends among five important European stock markets over the period 1975-1991. [less ▲]

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See detailThe Audiospinal Reaction in Parkinsonian Patients Reflects Functional Changes in Reticular Nuclei
Delwaide, Paul ULg; PEPIN, Jean-Louis ULg; Maertens De Noordhout, Alain ULg

in Annals of Neurology (1993), 33(1), 63-9

Audiospinal facilitation using the soleus H-reflex as a test was compared in 16 control subjects and 23 parkinsonian patients. In the patients, facilitation was significantly reduced during the 75 to 150 ... [more ▼]

Audiospinal facilitation using the soleus H-reflex as a test was compared in 16 control subjects and 23 parkinsonian patients. In the patients, facilitation was significantly reduced during the 75 to 150 msec after the conditioning stimulation. This reduction was seen bilaterally even in patients with a hemisyndrome. It was corrected by L-dopa but not by anticholinergic agents. Facilitation at the 75-msec delay showed an inverse linear correlation with the bradykinesia intensity (r = -0.7, p < 0.01). The results argue in favor of a reduced excitability of the nucleus reticularis pontis caudalis from which a reticulospinal tract emanates as effector of the audiospinal facilitation. This would represent another example of dysfunction of reticular nuclei in Parkinson's disease. [less ▲]

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See detailModelling the Arterial Wall by Finite Elements
Mosora, F.; Harmant, A.; Hallet, Claude ULg et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1993), 101(3, May-Jun), 185-91

The mechanical behaviour of the arterial wall was determined theoretically utilizing some parameters of blood flow measured in vivo. Continuous experimental measurements of pressure and diameter were ... [more ▼]

The mechanical behaviour of the arterial wall was determined theoretically utilizing some parameters of blood flow measured in vivo. Continuous experimental measurements of pressure and diameter were recorded in anesthetized dogs on the thoracic ascending and midabdominal aorta. The pressure was measured by using a catheter, and the diameter firstly, at the same site, by a plethysmograph with mercury gauge and secondly, by a sonomicrometer with ferroelectric ceramic transducers. The unstressed radius and thickness were measured at the end of each experiment in situ. Considering that the viscous component is not important relatively to the nonlinear component of the elasticity and utilizing several equations for Young modulus calculation (thick and thin wall circular cylindrical tube formulas and Bergel's equation) the following values were obtained for this parameter: 0.6 MPa-2 MPa in midabdominal aorta and 2 MPa-6.5 MPa in thoracic ascending aorta. The behaviour of the aorta wall was modelled considering an elastic law and using the finite element program "Lagamine" working in large deformations. The discretized equilibrium equations are non-linear and a unique axi-symmetric, iso-parametric element of 1 cm in length with 8 knots was used for this bi-dimensional problem. The theoretical estimation of radius vessel, utilizing a constant 5 MPa Young modulus and also a variable one, are in good agreement with the experimental results, showing that this finite element model can be applied to study mechanical properties of the arteries in physiological and pathological conditions. [less ▲]

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See detailOrganization of partner preference and sexual behavior and its nocturnal rhythmicity in male rats.
Bakker, Julie ULg; van Ophemert, J.; Slob, A. K.

in Behavioral Neuroscience (1993), 107(6), 1049-58

Male rats were neonatally treated with 1,4,6-androstatriene-3,17-dione (ATD), which blocks aromatization of testosterone (T) to estradiol (E2), from Days 0, 2, or 5 through 14. Adult partner preference ... [more ▼]

Male rats were neonatally treated with 1,4,6-androstatriene-3,17-dione (ATD), which blocks aromatization of testosterone (T) to estradiol (E2), from Days 0, 2, or 5 through 14. Adult partner preference behavior (PPB; choice between estrous female rat [F] and active male rat [M]) was studied in the early part of the dark phase of the light-dark (LD) cycle. ATD Day 0 Ms showed a preference for the stimulus M or showed no preference for either of the stimulus Ss. Controls preferred the estrous F. ATD Days 2 and 5 Ms showed PPB intermediate between ATD Day 0 Ms and controls. Thus the neonatally sensitive period for organization of adult PPB extends beyond Day 5. Furthermore, PPB showed a nocturnal rhythmicity in ATD Ms but not in controls. In the late part of the dark phase, all Ms showed a preference for the stimulus F. ATD Days 2 and 5 Ms and control Ms were no longer different in PPB, but ATD Day 0 Ms still showed significantly lower preference scores for F than all other Ms. Thus the E2 metabolite of T suppresses organization of an adult nocturnal rhythm in PPB. [less ▲]

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See detailInventaire préliminaire sur le patrimoine campanaire de l'église Saint-Servais à Liège
Marganne, Marie-Hélène ULg; Mélard, Marc

in Bulletin de la Société Royale Le Vieux-Liège (1993), 261

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See detailL’Iynge dans le discours mythique et les procédures magiques
Pirenne-Delforge, Vinciane ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (1993), 6

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See detailIn vitro susceptibility of Clostridium perfringens isolated from farm animals to growth-enhancing antibiotics.
Devriese, L. A.; Daube, Georges ULg; Hommez, J. et al

in Journal of Applied Bacteriology (1993), 75

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See detailStructure of the 16 S ribosomal RNA of the thermophilic cyanobacterium Chlorogloeopsis HTF (‘Mastigocladus laminosus HTF’) strain PCC75 18, and phylogenetic analysis
Wilmotte, Annick ULg; Van Der Auwera, Gert; De Wachter, Rupert

in FEBS Letters (1993), 317

The thermophilic cyanobacterial strain, PCC7518, originally identified as ‘Mu~tigocludus hminosus HTF’ does not show branchings or heterocysts. The absence of branchings supports the later assignment to ... [more ▼]

The thermophilic cyanobacterial strain, PCC7518, originally identified as ‘Mu~tigocludus hminosus HTF’ does not show branchings or heterocysts. The absence of branchings supports the later assignment to the genus Chlorogloeopsu. The absence of heterocysts may be the result of a mutation because heterocysts were observed in the original isolate. Alternatively, contamination may have happened. To solve this problem, the 16 S rRNA sequence was determined and used to infer a secondary structure model and build distance trees. The trees showed that strain PCC7518 belongs to the cluster of heterocystous species and has most probably lost the abihty to produce heterocysts by mutation. It is only distantly related to Chlorogloeopsis fritschii PCC67 18. [less ▲]

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See detailMiddle and Upper Devonian Miospore Zonation of Eastern Europe.
Avkhimovitch, V.I.; Tchibrikova, E.V.; Obukhovskaya, T.G. et al

in Bull. Centres Rech. Explor.-Prod. Elf Aquitaine, (1993), 17

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See detailAmineptine and response timing in the rat
Lejeune, Helga ULg; Hermans, Isabelle ULg; Mocaer, E. et al

in Behavioural Processes (1993), 29

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See detailColonne lithologique du sondage de Latour (494 m): une coupe de référence pour le Secondaire de la Gaume
Boulvain, Frédéric ULg; Monteyne, R.

in Professional paper Belgian geological survey (1993), 267

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See detailAn efficient interpolation algorithm for Fourier and diffractive optics
Roose, Stéphane ULg; Brichau, Bart; Stijns, Erik

in Optics Communications (1993), 97(5-6), 312-318

An alternative algorithm for the computation of diffraction (Fourier) integrals is described. Its computation time is comparable with the computation time of an FFT-algorithm combined with zero-framing ... [more ▼]

An alternative algorithm for the computation of diffraction (Fourier) integrals is described. Its computation time is comparable with the computation time of an FFT-algorithm combined with zero-framing. On the other hand it allows a free choice of resolution, as in numerical integration. The features of this algorithm are illustrated on the calculation of a PSF of an aberrated lens. [less ▲]

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See detailLa gestion de l'espace
Bock, Laurent ULg

in Bulletin des Recherches Agronomiques de Gembloux (1993), 28(2-3), 115-414

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See detailFollicular Dendritic Cells Do Not Produce Tnf-Alpha nor its Receptor
Mancini, I.; Bosseloir, A.; Hooghe-Peters, E. et al

in Advances in Experimental Medicine and Biology (1993), 329

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See detailMonads and chaos : the vitality of Leibniz's philosophy
Bouquiaux, Laurence ULg

in Diogenes (1993)

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See detailComputer Originated Polarizing Holographic Optical Element recorded in Photopolymerizable layers
Carré, Christiane; Habraken, Serge ULg; Roose, Stéphane ULg

in Optics Letters (1993), 18(9), 738-740

The photosensitive system that is used in most cases to produce holographic optical holograms is dichromated gelatin. Other materials may be used, in particular, photopolymerizable layers. In the present ... [more ▼]

The photosensitive system that is used in most cases to produce holographic optical holograms is dichromated gelatin. Other materials may be used, in particular, photopolymerizable layers. In the present investigation, we set out to use the polymer developed in the Laboratoire de Photochimie Générale in Mulhouse in order to duplicate a computer-generated hologram. Our technique is intended to generate polarizing properties. We took into account the fact that no wet chemistry processing is required; grating fringe spacings are not distorted through chemical development. [less ▲]

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See detailEnergy Analysis on Small to Medium Sized H-Bonded Complexes
Dive, Georges ULg; Dehareng, Dominique ULg; Ghuysen, Jean-Marie ULg

in Theoretica Chimica Acta (1993), 85(6), 409-421

Dimers (water-methanol, guanine-cytosine) as well as trimers (methanol-water-imidazole, formamide-methylformate-formamide), are studied as H-bonded complexes of increasing complexity. All the investigated ... [more ▼]

Dimers (water-methanol, guanine-cytosine) as well as trimers (methanol-water-imidazole, formamide-methylformate-formamide), are studied as H-bonded complexes of increasing complexity. All the investigated conformations have been fully optimized. In particular, it is the first time that all the intra- and intermolecular parameters of the guanine-cytosine complex are left variable. In minimal basis sets, the planar conformation has been found to be a first-order critical point. The minimal basis set MINI-1 has been adapted to provide nearly planar amides. The stability of the complexes is accounted for by four energy components of the same order: the first-order term (electrostatic + exchange), the polarization, the charge transfer and the correlation terms. In the case of the studied trimers, the energy components, apart from the electrostatic one, have been found to be nearly additive. [less ▲]

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See detailAspects cliniques de la neoplasie endocrinienne multiple de type 2 (NEM-2).
Moreau, L.; Beckers, Albert ULg

in Revue Médicale de Liège (1993), 48(6), 316-22

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See detailImprovement Yarrowia lipolytica lipase production by mutant selection.
Destain, Jacqueline ULg; Roblain, D.; Thonart, Philippe ULg

in Archives Internationales de Physiologie et de Biochimie (1993), 101(B1-B25),

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See detailDRC1 expression on normal and pathological lymphoid cells.
Antoine, Nadine ULg; Heinen, Ernst ULg; Marcoty, C. et al

in Advances in Experimental Medicine and Biology (1993), 329

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See detailThe role of GnRH agonists in the endoscopic treatment of endometriosis and fibromyomas.
Donnez, Jacques; NISOLLE, Michelle ULg; Grandjean, P. et al

in Contraception, Fertilite, Sexualité (1992) (1993), 21(1), 59-62

Uterine myomas and endometriosis are benign pathologies frequently encountered in women. Myomas are often associated with infertility and/or menorrhagia particularly if they are sub-mucosal. Endometriosis ... [more ▼]

Uterine myomas and endometriosis are benign pathologies frequently encountered in women. Myomas are often associated with infertility and/or menorrhagia particularly if they are sub-mucosal. Endometriosis is diagnosed in more than 35% of infertile patients. These two common pathologies are oestrogen-dependent and the administration of a GnRH agonist has been proposed as a non-surgical approach to the treatment of myomas and endometriosis. GnRH agonists cannot, however, be considered as definitive medical therapy because most myomas and endometriotic cysts return to their initial size within 4 months following the cessation of treatment. Moreover, because of the menopausal-like state that they induce, GnRH agonists provoke bone demineralization and for this reason, their long-term use is not recommended. These agents should, therefore, be considered as an adjuvant preoperative therapy. The aim is, above all, to achieve a preoperative reduction of tumour size, thus facilitating the endoscopic surgery: either hysteroscopic resection in the case of sub-mucosal myomas, or vaporization of ovarian cysts in the case of cystic endometriotic lesions. [less ▲]

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See detailEarly prediction of response to recombinant human erythropoietin in patients with the anemia of renal failure by serum transferrin receptor and fibrinogen.
Beguin, Yves ULg; Loo, Martine; R'Zik, Samir ULg et al

in Blood (1993), 82(7), 2010-6

Recombinant human erythropoietin (rHuEpo) has been shown to be effective in correcting the anemia of chronic renal failure, but the dose needed may be variable. The reason for this variation is not known ... [more ▼]

Recombinant human erythropoietin (rHuEpo) has been shown to be effective in correcting the anemia of chronic renal failure, but the dose needed may be variable. The reason for this variation is not known, but several factors could be involved, such as iron deficiency, inflammation, aluminum intoxication, hyperparathyroidism, blood losses, or marrow dysfunction. Treatment with rHuEpo was given intravenously thrice weekly after hemodialysis to 64 consecutive unselected patients with the anemia of chronic renal failure. The starting dose was 50 U/kg/dose, which was increased to 75 and 100 U/kg/dose if no response was observed after 1 and 2 months of treatment. After a minimum follow-up of 6 months, response was evaluated as early (hematocrit [Hct] > or = 30% before 3 months) or late (Hct > or = 30% after 3 months) response, or failure (target Hct not attained). We examined the value of various laboratory parameters (baseline values and early changes) as predictors of response to rHuEpo. The best prediction by pretreatment parameters only was obtained with baseline serum transferrin receptor (TfR) (< or > or = 3,500 ng/mL) and fibrinogen (< or > or = 4 g/L): 100% response rate when both parameters were low, versus only 29% when they were both high, and versus 67% when one was low and the other high. When the 2-week TfR increment was greater than 20%, the response rate was 96%. When TfR increment was less than 20%, the response rate was 100% when baseline TfR and fibrinogen were low, 12% when fibrinogen was elevated, and 62% when fibrinogen was low but baseline TfR high. The predictive value of baseline TfR and fibrinogen and of the 2-week increment of TfR was confirmed by life table analysis and stepwise discriminant analysis. Major reasons for failure or late response were identified and included subclinical inflammation, iron deficiency, functional iron deficiency, marrow disorders, hemolysis, bleeding, and low Epo dose. We conclude that response to rHuEpo can be predicted early by pretreatment fibrinogen and TfR, together with early changes of TfR levels. These prognostic factors illustrate the importance of the early erythropoietic response, subclinical inflammation, and functional iron deficiency. Early recognition of a low probability of response in a given patient could help identify and correct specific causes of treatment failure to hasten clinical improvement and avoid prolonged ineffective use of an expensive medication. [less ▲]

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See detailEchographic Characterization of Carotid Plaques
VAN DAMME, Hendrik ULg; TROTTEUR, Geneviève ULg; Vivario, M. et al

in Acta Chirurgica Belgica (1993), 93(5), 233-8

The histology of the endarterectomy specimen was compared with the preoperative echopattern of 154 plaques. Thirty-four ultrasound images were of poor quality. The 120 adequate echographies revealed 22 ... [more ▼]

The histology of the endarterectomy specimen was compared with the preoperative echopattern of 154 plaques. Thirty-four ultrasound images were of poor quality. The 120 adequate echographies revealed 22 dense hyperechogenic homogeneous plaques, 28 soft hypoechogenic homogeneous plaques, 53 inhomogeneous plaques, and 13 mixed plaques. According to the surface, lesions were subdivided as smooth (n = 63) or irregular (n = 57). Echography recognized fibrous plaques (dense homogeneous hyperechogeneous lesions), with a specificity of 87% and a sensitivity of 56%. Recent intraplaque haemorrhage is echographically apparent as a hypoechogenic area in 88% of cases, what corresponds to a specificity of 79% and a sensitivity of 75%. Echography proved to be more accurate than angiography in determining the presence or absence of ulceration. The ability to characterize the pathology of carotid atheroma by duplex scan make the clinicopathologic correlation of carotid plaques of practical importance. [less ▲]

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See detailDe l'emploi des tests dans l'expertise psychologique
Mormont, Christian ULg

in Bulletin de Psychologie (1993), 47(415), 235-239

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See detailTotal intravenous anesthesia in South-African genetic porphyria (variegate porphyria)
Bichel, Th; Joris, Jean ULg; Jacquet, N. et al

in Acta Anaesthesiologica Belgica (1993), 44(1), 25-29

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See detailApplications de l'échographie en reproduction bovine. 2. L'utérus gestant et non-gestant.
Hanzen, Christian ULg; Laurent, Yves; Jakovljevic, Samy

in Annales de Médecine Vétérinaire (1993)

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See detailApamin increases NMDA-induced burst-firing of rat mesencephalic dopamine neurons.
Seutin, Vincent ULg; Johnson, S. W.; North, R. A.

in Brain Research (1993), 630(1-2), 341-4

Intracellular recordings made in vitro from rat midbrain dopamine neurons showed that apamin (100 nM) did not alter the regular spontaneous firing of the neurons, but it increased the occurrence of bursts ... [more ▼]

Intracellular recordings made in vitro from rat midbrain dopamine neurons showed that apamin (100 nM) did not alter the regular spontaneous firing of the neurons, but it increased the occurrence of bursts of action potentials in N-methyl-D-aspartate. Apamin appeared to facilitate burst-firing induced by NMDA because, by blocking an outward calcium-activated potassium current, it increased the depolarizing action of NMDA. [less ▲]

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See detailDifferential location of nucleic acids within interchromatin granule clusters.
Thiry, Marc ULg

in European Journal of Cell Biology (1993), 62(2), 259-69

We have examined in great detail the distribution of nucleic acids within interchromatin granule clusters in different cell types by means of various immunocytochemical approaches. Using the in situ ... [more ▼]

We have examined in great detail the distribution of nucleic acids within interchromatin granule clusters in different cell types by means of various immunocytochemical approaches. Using the in situ polyadenylate nucleotidyl transferase-immunogold technique for RNA detection or anti-RNA antibodies, we decisively demonstrate the presence of appreciable amount of RNA in clusters of interchromatin granules of untreated cells. Neither the in situ terminal deoxynucleotidyl transferase-immunogold technique nor anti-DNA antibodies, nor the in situ nick-translation technique for DNA detection have revealed any DNA in the interchromatin granule clusters. However, dispersed chromatin sensitive to DNase I are found at the borders and in the close vicinity of interchromatin granule clusters. The results indicate that interchromatin granule clusters should not be nuclear structures directly involved in RNA transcription but rather in some other steps of RNA metabolism. [less ▲]

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See detailMaghrébins en Europe
Martiniello, Marco ULg; Geisser, V.; Lorcerie, F. et al

in Annuaire de l'Afrique du Nord (1993), XXXII

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See detailCompte rendu de J. HEERS, Précis d’histoire du Moyen Âge, 4e éd.
Marchandisse, Alain ULg

in Moyen Age (Le) (1993), 99

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See detailLa fonction centrale du thymus dans la reconnaissance des fonctions neuroendocrines par les lymphocytes T au cours de leur développement
Geenen, Vincent ULg; Martens, Henri ULg; Cormann-Goffin, N. et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1993), 101(4, Jul-Aug), 19-22

The dual physiological role of the thymus in T cell positive and negative selection appears prominent in the establishment of appropriate host immune defenses. However, the cellular and molecular ... [more ▼]

The dual physiological role of the thymus in T cell positive and negative selection appears prominent in the establishment of appropriate host immune defenses. However, the cellular and molecular mechanisms underlying those thymic functions begin only to be understood. On the basis of our previous investigations about the thymic expression of different neuroendocrine-related signals, we have advanced a model which transposes at the peptide level the intervention of this primary lymphoid organ in both T cell positive and negative selective processes. There is now ample evidence that the thymic subcapsular and medullary epithelium is the site for synthesis of neurohypophysial (NHP)-related peptides (reviewed in Geenen et al., 1992a). We have also demonstrated that the epithelial component of thymic "nurse" cells (TNC) synthesizes NHP-related peptides and expresses a neuroendocrine-like phenotype (Geenen et al., 1988a). This observation was a remarkable example of the intimate neuroendocrine-immune interactions that take place during T cell ontogeny. Further immunocytochemical analyses have confirmed that one dominant NHP-related epitope belongs to the oxytocin (OT) lineage of the NHP peptide superfamily (Robert et al., 1991, 1992). The intrathymic coexpression of this OT-like epitope with a neurophysin protein domain is a strong argument for a local synthetic process similar to the hypothalamo-NHP one. However, the absence of ir-OT in secretory granules of thymic epithelial cells (TEC), as well as of NHP-related peptides in the supernatant of TEC cultures questioned the application to the thymus of the classical neurosecretory model established for hypothalamic magnocellular neurons (Scharrer [less ▲]

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See detailCaractéristiques du nid et du site de nidification chez le grèbe huppé (Podiceps cristatus). Influence sur le succès des éclosions
Marechal, Corinne ULg

in Cahiers d'Ethologie (1993), 13(1), 1-34

The study aimed at determining the influence of nest and nest-site characteristics on breeding success in a population of great Crested grebes (Podiceps cristatus) nesting on an old máeander of the river ... [more ▼]

The study aimed at determining the influence of nest and nest-site characteristics on breeding success in a population of great Crested grebes (Podiceps cristatus) nesting on an old máeander of the river Meuse on the Belgium-Dutch border. Evolution of clutches has been followed during two breeding seasons (1991 and 1992). The features of the nests and the nest-sites have been subjected to a multivariate analysis. It’s difficult to distinguish clearly between successful and unsuccessful nests during the same year. Moreover, most characteristics are not constant any year. Only two parameters seem to have the same effects on nesting success in 1991 and 1992 : the distance from nest to nearest neighbour and the water level in nest site. Nests distant from another nest and in deep water were less successful. Other possible causes of nesting failure have been tackled (investigator disturbance, bad weather conditions, fall of eggs, clutch-destruction by human). [less ▲]

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See detailEffects on performance and meat characteristics of a diet supplemented with fat during the finishing period of growing fattening bulls
Hollo, Véronique; Marche, Christian; Dufrasne, Isabelle ULg et al

in Animal Production (1993), 56

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See detailSpelling en spellingverandering : een slingerbeweging in de tijd
Vromans, Joseph ULg

in Nederlands van Nu (1993), 41

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See detailMeasurement of the 2s2p2(4P)3s 3P2 lifetime in N II by beam-foil-laser spectroscopy
Bastin, Thierry ULg; Baudinet-Robinet, Y.; Garnir, Henri-Pierre ULg et al

in Journal Physical II (1993), 3

An accurate value for the radiative lifetime of the 2s2p2(4P)3s3P2 level in N II has been obtained using the beam-foil-laser spectroscopy method. The result (T = 0.456 ± 0.020 ns ) is shorter than the ... [more ▼]

An accurate value for the radiative lifetime of the 2s2p2(4P)3s3P2 level in N II has been obtained using the beam-foil-laser spectroscopy method. The result (T = 0.456 ± 0.020 ns ) is shorter than the beam-foil lifetime values reported previously for the 3s' 3P term. No theoretical value for the lifetime of this term is available at the present time. [less ▲]

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See detailA concise guide to the temporal maze
Richelle, Marc ULg

in Psychologica Belgica (1993), 33(2), 135-145

The paper provides a concise historical survey of the expanding field of time psychology, pointing to the important contributions, in its early stages as well as today, of European psychologists. An ... [more ▼]

The paper provides a concise historical survey of the expanding field of time psychology, pointing to the important contributions, in its early stages as well as today, of European psychologists. An evaluation of past and current research is proposed, and prospects for further development suggested, especially with regard to neglected areas and to issues related to applied situations. [less ▲]

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See detailMonoamine Oxidase Inhibitors and Anesthesia: An Updated Literature Review
Blom-Peters, L.; Lamy, Maurice ULg

in Acta Anaesthesiologica Belgica (1993), 44(2), 57-60

Safe anesthesia for patients taking MAOIs has been possible since the 1980s using judicious choice of agents. The introduction of a new class of MAOIs (RIMA) has increased the margin of safety for these ... [more ▼]

Safe anesthesia for patients taking MAOIs has been possible since the 1980s using judicious choice of agents. The introduction of a new class of MAOIs (RIMA) has increased the margin of safety for these anesthetics. These drugs allow selective and rapidly reversible inhibition of type A-MAO. The pharmacologic effects of this new class of drug as well as their potential interactions with agents used in anesthesia are reviewed. [less ▲]

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See detailMathematical Programming Methods for Constrained Optimization: Dual Methods
Fleury, Claude ULg

in Progress in Astronautics and Aeronautics (1993), 150

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See detailMetabolism of Thiamine Triphosphate in Rat Brain: Correlation with Chloride Permeability
Bettendorff, Lucien ULg; Peeters, Maryline; Wins, Pierre et al

in Journal of Neurochemistry (1993), 60(2), 423-434

Our results show that a net synthesis of thiamine triphosphate (TTP) can be demonstrated in vitro using rat brain extracts. The total homogenate was preincubated with thiamine or its diphosphate ... [more ▼]

Our results show that a net synthesis of thiamine triphosphate (TTP) can be demonstrated in vitro using rat brain extracts. The total homogenate was preincubated with thiamine or its diphosphate derivative (TDP), centrifuged, and washed twice. With TDP (1 mM) as substrate, a 10-fold increase in TTP content was observed in this fraction (nuclear fraction, membrane vesicles). A smaller, but significant, increase was observed in the P2 fraction (mitochondrial/synaptosomal fraction). In view of the low TTP content of our fractions, it was carefully assessed that authentic TTP was being formed. Incorporation of radioactivity from [beta-32P]TDP and [gamma-32P]ATP in TTP suggests that these two compounds are its precursors. Furthermore, TTP synthesis was inhibited by ADP and relatively low concentrations of Zn2+. These results suggest that TTP synthesis is catalyzed by an ATP:TDP transphosphorylase rather than by the cytoplasmic adenylate kinase that may be present in the vesicles. After osmotic lysis of the vesicles at alkaline pH, TTP was recovered in protein-bound form. Concomitantly, a soluble thiamine triphosphatase, with alkaline pH optimum, was also released from the vesicles. No net synthesis could be obtained in the cytosolic fraction or in detergent-solubilized systems. Like TTP synthesis, chloride permeability of the vesicles was increased when the homogenate had been incubated with thiamine and particularly with TDP. Our results suggest a regulatory role of TTP on chloride permeability, but the target remains to be characterized. [less ▲]

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See detailInfluence of body size on tibial nerve somato sensory evoked potentials in dogs
Poncelet, Luc; Michaux, Charles; Balligand, Marc ULg

in American Journal of Veterinary Research (1993)

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See detailAspects cliniques de la néoplasie endocrinienne multiple de type 2 (NEM-2)
Moreau, L.; Beckers, Albert ULg

in Médecine & Chirurgie Digestives (1993), 23(1), 17-20

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See detailSodium et hypertension artérielle essentielle. Nouveau refrain pour une vieille chanson
Krzesinski, Jean-Marie ULg

in L'Information Cardiologique (1993), 17(7), 299-304

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See detailLog jam effect on bed-load mobility from experiments conducted in a small gravel-bed channel
Assani, Ali; Petit, François ULg

in Memorial symposium Pro. J. De Ploey Experimental geomorphology and landscape ecosystem changes (1993)

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See detailLate Famennian miospore assemblages from the Bergisch Gladbach - Paffrath Syncline, Rhenish Slate Mountains, Germany
Hartkopf-Fröder, C; Streel, Maurice ULg

in Annales de la Société Géologique de Belgique (1993), 116(2), 333-357

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See detailRésultats de la mesure de la concentration en poussière dans l'air de 12 porcheries
Marlier, Didier ULg; Nicks, Baudouin ULg; Canart, Bernard

in Annales de Médecine Vétérinaire (1993), 137

Aerial dust concentrations in 12 pig houses Dust concentration was measured during 3 days at hourly intervals in 5 farrowing houses and 7 fattening houses. The number concentration of aerial particles was ... [more ▼]

Aerial dust concentrations in 12 pig houses Dust concentration was measured during 3 days at hourly intervals in 5 farrowing houses and 7 fattening houses. The number concentration of aerial particles was measured using a counter which sizes the total numbers in 5 categories: from 0.3-0.5 mum to > 5 mum. The mean dust concentrations were significantly higher in the farrowing houses than in the fattening houses (179 +/- 91 vs 97 +/- 65 particles/ml). Over a 24-h period, the ratio between the highest and the lowest hourly concentrations was 3 +/- 1 in the farrowing houses and 5 +/- 4 in the fattening houses; the difference between the 2 types of houses is significant. The smallest particles were the most numerous; 82 % of the aerial particles were in the size range 0.3-0.5 mum, with less than 1 % being 5 mum or larger. During the most polluted hours, there was proportionally more particles in the size range 0.5-1 mum and significantly less particles in the size ranges 1-2 mum and 2-5 mum, as compared to the less polluted hours. This study shows that most of the aerial particles in piggeries are smaller than 5 mum, the size below which deposition is regarded to occur in the lower respiratory tract, the farrowing houses being more polluted than the fattening houses. [less ▲]

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See detailLaparoscopic myolysis with the Nd:YAG laser.
NISOLLE, Michelle ULg; Smets, Mireille; Malvaux, Vincent et al

in Journal of Gynecologic Surgery (1993), 9(2), 95-9

Laparoscopic myomectomy can be carried out in cases of subserosal and intramural fibroids. Laparoscopic myolysis can be proposed as an alternative to laparoscopic myomectomy in cases of large or multiple ... [more ▼]

Laparoscopic myomectomy can be carried out in cases of subserosal and intramural fibroids. Laparoscopic myolysis can be proposed as an alternative to laparoscopic myomectomy in cases of large or multiple intramural fibroids in women aged over 40 or not desiring to bear more children but wishing to avoid a future hysterectomy. The authors report the technique and the long-term results in a series of 48 women with fibroids treated by myolysis. Because of the risk of bowel adhesions, further studies with another type of laser fiber are required. [less ▲]

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See detailOnce daily administration of amikacin. Adaptation to neonatology for infants less than 3 days of postnatal age
Battisti, Oreste ULg

in Médecine et Maladies Infectieuses (1993), 23

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See detailMicrosatellite mapping of the gene causing weaver disease in cattle will allow the study of an associated QTL
Georges, Michel ULg; Lathrop, M.; Dietz, A. B. et al

in Proceedings of the National Academy of Sciences of the United States of America (1993), 90

A genetic disease in cattle, progressive degenerative myeloencephalopathy (weaver disease), is associated with increased milk production. This association could result from population stratification, from ... [more ▼]

A genetic disease in cattle, progressive degenerative myeloencephalopathy (weaver disease), is associated with increased milk production. This association could result from population stratification, from a pleiotropic effect of a single gene, or from linkage disequilibrium between the gene causing weaver disease and a quantitative trait locus (QTL) for milk production. To test these hypotheses, we performed an extensive linkage study in a bovine pedigree segregating for the weaver condition and identified a microsatellite locus (TGLA116) closely linked to the weaver gene (zmax, 8.15; theta, 0.03). TGLA116 and, by extension, the weaver locus were assigned to bovine synteny group 13. This microsatellite can be used to identify weaver carriers, to select against this genetic defect, and to study the effect of the corresponding chromosomal region on milk production in Brown Swiss and other breeds of cattle. [less ▲]

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See detailMiddle Devonian to Lower Carboniferous Miospores from selected boreholes in Amazonas and Parnaiba basins (Brazil): additional data, synthesis, and correlation.
Loboziak, S; Streel, Maurice ULg; Caputo, MV et al

in Documents du laboratoire de Géologie de Lyon (1993), 125

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See detailClonidine and ketanserin both are effective treatment for postanesthetic shivering.
Joris, Jean ULg; Banache, Maryse; Bonnet, Francis et al

in Anesthesiology (1993), 79(3), 532-9

BACKGROUND: Although meperidine is an effective treatment of postanesthetic shivering, its mechanism of action remains unknown. Investigation of other drugs might help clarify the mechanisms by which ... [more ▼]

BACKGROUND: Although meperidine is an effective treatment of postanesthetic shivering, its mechanism of action remains unknown. Investigation of other drugs might help clarify the mechanisms by which shivering can be controlled. Accordingly, we investigated the efficacy of clonidine, an alpha 2-adrenergic agonist, and ketanserin, a 5-hydroxytryptamine antagonist, in treating postanesthetic shivering. METHODS: First, 54 patients shivering after general anesthesia were allocated randomly to receive an intravenous bolus of saline, 150 micrograms clonidine, or 10 mg ketanserin. A second study explored the dose-dependence of clonidine. Forty shivering patients were given saline or clonidine, 37.5, 75, or 150 micrograms. RESULTS: The duration of shivering was significantly shorter in those given clonidine (2.1 +/- 0.9 min) than in the other two groups and shorter in the ketanserin group (4.3 +/- 0.9 min) than in the saline group (12.0 +/- 1.6 min). Clonidine and ketanserin significantly decreased systolic arterial blood pressure when compared to saline. Core rewarming was significantly slower in the clonidine group. In the second study, 37.5 micrograms clonidine was no more effective than saline. Two minutes after treatment, 150 micrograms obliterated shivering in all patients. Five minutes after treatment, all patients given 75 micrograms had stopped shivering. Systolic arterial pressure and heart rate decreased significantly in patients given 75 and 150 micrograms clonidine. CONCLUSIONS: Clonidine (150 micrograms) and ketanserin (10 mg) both are effective treatment for postanesthetic shivering. The effect of clonidine on shivering is dose-dependent: whereas 37.5 micrograms had no effect, 75 micrograms clonidine stopped shivering within 5 min. [less ▲]

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See detailInventaire des végétaux éodévoniens de Belgique
Gerrienne, Philippe ULg

in Annales de la Société Géologique de Belgique (1993), 116

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See detailLocalisation scintigraphique de tumeurs neuroendocrines et de leurs métastases par un analogue de la somatostatine: [111In-DTPA-d-phe1] octréotide.
Beckers, Albert ULg; Pham, V. T.; Abs, R. et al

in Revue Médicale de Liège (1993), 48(6), 326-34

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See detailApport de la mesure ambulatoire de la pression artérielle dans une consultation d'hypertension artérielle
Saint-Remy, Annie ULg; Dubois, Bernard ULg; Krzesinski, Jean-Marie ULg et al

in Journal de Cardiologie [= JDC] = Tijdschrift voor Cardiologie [= TVC] (1993), 5(1), 6-13

La fréquence du syndrome de la blouse blanche, l'importance de la charge tensionnelle et de la variabilité de la pression artérielle au cours du nycthémère ont été analysées dans une population de 181 ... [more ▼]

La fréquence du syndrome de la blouse blanche, l'importance de la charge tensionnelle et de la variabilité de la pression artérielle au cours du nycthémère ont été analysées dans une population de 181 patients ayant bénéficié d'un enregistrement de la pression artérielle en ambulatoire pendant 24 heures. En dépit d'une bonne corrélation entre la mesure clinique de la pression artérielle et la pression moyenne de jour ou de 24 heures, on observe une discordance entre les niveaux de pression fournis par les deux méthodes (la pression clinique étant supérieure à la pression en ambulatoire et cela d'autant plus que la pression clinique est élevée). Lors de l'évaluation de l'efficacité du traitement antihypertenseur, l'analyse des tracés montre qu'un tiers des patients traités ont des pressions normalisées, alors que deux tiers d'entre eux conservent des pressions de jour et de 24 heures nettement supérieures aux critères définissant l'hypertension artérielle. Par ailleurs, cette étude souligne également la supériorité des valeurs de pression en ambulatoire (surtout la pression systolique) par rapport à la pression clinique comme prédicteur d'une hypertrophie ventriculaire gauche. Ces observations confirment l'intérêt de cette technique non invasive de mesure de la pression artérielle moyenne tant pour objectiver l'effet blouse blanche, et ainsi préciser le diagnostic d'une hypertension artérielle, que pour s'assurer du contrôle de la pression par les thérapeutiques antihypertensives. [less ▲]

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See detailCompte-rendu de J. Cerny : Papyrus hiératiques de Deir-el-Médineh
Winand, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1993), 78

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See detailLe temps de la formation professionnelle pour les jeunes chômeurs
Robert, Jocelyne ULg

in Revue de l'Institut de Sociologie (1993), 1-4

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See detailUnimolecular reaction dynamics from Kinetic Energy Release Distributions. 1 - Dissociation of Bromobenzene Ions.
Lorquet, Jean-Claude ULg; Leyh, Bernard ULg

in Organic Mass Spectrometry (1993), 28

Preliminary data on a new method for extracting data from the kinetic energy release distribution of metastable fragment ions are presented. This method can give information concerning the energy ... [more ▼]

Preliminary data on a new method for extracting data from the kinetic energy release distribution of metastable fragment ions are presented. This method can give information concerning the energy threshold of the reaction and the energy dependence of the rate constant (i.e. its logarithmic derivative). It was applied to bromine loss from bromobenzene cations. [less ▲]

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See detailMicrosatellite mapping of a gene affecting horn development in Bos taurus
Georges, Michel ULg; Drinkwater, R.; Lefort, A. et al

in Nature Genetics (1993), 4(2), 206-210

The presence or absence of horns in Bos taurus is thought to be under the genetic control of the autosomal polled locus, characterized by two alleles: P dominant over p, and causing the polled or hornless ... [more ▼]

The presence or absence of horns in Bos taurus is thought to be under the genetic control of the autosomal polled locus, characterized by two alleles: P dominant over p, and causing the polled or hornless phenotype. We have demonstrated genetic linkage between the polled locus and two microsatellite markers, GMPOLL-1 and GMPOLL-2, and have assigned the corresponding linkage group to bovine chromosome 1. This confirms the existence of the postulated polled locus and the hypothesized inheritance pattern. It will allow marker assisted selection for the polledness trait in breeding programs and is a first step towards positional cloning and molecular study of a gene that has been subjected to both natural and artificial selection. [less ▲]

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See detailPilot study of flesinoxan in major depression. Effect on REM latency and body temperature
ANSSEAU, Marc ULg; PITCHOT, William ULg; Gonzalez Moreno, Antonio et al

in Human Psychopharmacology (1993)

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See detailPalaeolithic and Mesolithic Research in Belgium, 1993: le Trou Magrite, Huccorgne & l'Abri du Pape
Straus, Lawrence; Otte, Marcel ULg; Cordy, Jean-Marie ULg et al

in Old World Archaeology Newsletter (1993), XVII(1), 17-24

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See detailComparison of the cardiac pumping capability and cardiac pumping reserve in double muscled and conventional calves
Amory, Hélène ULg; Mc Entee, Kathleen ULg; Linden, Annick ULg et al

in Canadian Journal of Physiology & Pharmacology (1993), 71(12), 946-951

Hereditary muscular hypertrophy is a character that has been selected in several animal species for industrial meat production. The selection of this character in cattle produces animals of exceptional ... [more ▼]

Hereditary muscular hypertrophy is a character that has been selected in several animal species for industrial meat production. The selection of this character in cattle produces animals of exceptional commercial value but ones with a lower aerobic capacity than that of conventional cattle. The purpose of this work was to study the role of cardiac function as a potential limiting factor of aerobic capacity in double-muscled calves. Two groups of healthy calves were studied, one consisting of nine calves of conventional conformation and the other of nine double-muscled calves. Pulmonary arterial and capillary wedge, central venous, and systemic arterial pressures were measured by fluid-filled catheters and recorded together with the electrocardiogram. Cardiac output was measured by the thermodilution technique. From these measurements, the heart rate, the cardiac and the stroke indices, the pulmonary and the systemic vascular resistances, and the cardiac power output were calculated. The parameters were recorded under basal resting conditions and during incremental dobutamine challenge, which allowed determination of the resting cardiac power output, the cardiac pumping capability, and the cardiac reserve. Dobutamine challenge induced a significant rise in cardiac and stroke indices, heart rate, and cardiac power output, a significant decrease in pulmonary and systemic vascular resistances, and no change in systemic and pulmonary arterial pressures. The cardiac reserve obtained in the present study was low in comparison with those previously reported in humans, dogs, and horses. This may be related to the poor running capability of bovine species relative to that of the former species.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailApplying the Lagamine model to compute land subsidence in Shanghai
Dassargues, Alain ULg; Schroeder, Christian ULg; Li, Xiang Lin

in Bulletin of Engineering Geology & the Environment (1993), 47

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See detailPeut-on réfléchir sereinement sur les migrations humaines ?
Martiniello, Marco ULg

in Agenda Interculturel (1993), 113

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See detailRapid and Selective Isolation of Follicular Dendritic Cells by Low Speed Centrifugations on Discontinuous Bsa Gradients
Marcoty, C.; Heinen, Ernst ULg; Antoine, Nadine ULg et al

in Advances in Experimental Medicine and Biology (1993), 329

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See detailMutational analysis of the p50 subunit of NF-kappa B and inhibition of NF-kappa B activity by trans-dominant p50 mutants.
Bressler, P.; Brown, K.; Timmer, W. et al

in Journal of Virology (1993), 67(1), 288-93

The NF-kappa B family of DNA-binding proteins regulates the expression of many cellular and viral genes. Each of these proteins has an N-terminal region that is homologous to the c-Rel proto-oncogene ... [more ▼]

The NF-kappa B family of DNA-binding proteins regulates the expression of many cellular and viral genes. Each of these proteins has an N-terminal region that is homologous to the c-Rel proto-oncogene product, and this Rel homology region defines both DNA binding and protein dimerization properties of the individual proteins. Most of the NF-kappa B family members have been shown to associate with themselves or with each other to form homodimers or heterodimers, and previous studies have shown that dimerization of NF-kappa B factors is necessary to provide a functional DNA binding domain. We have used site-directed mutagenesis to identify regions in the Rel homology domain of the p50/NF-kappa B protein that are important for DNA binding and protein dimerization. Our studies have identified mutations of p50 that interfere with DNA binding only and those that interfere with protein dimerization. Mutations of p50 which disrupt only DNA binding were still able to associate with other members of the NF-kappa B protein family. We demonstrate that such heterodimeric complexes inhibit transcriptional activation mediated in trans through a cis-acting kappa B motif; therefore, we have identified trans-dominant negative mutants of p50. [less ▲]

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See detailChanges In The Hypophyseal-Gonadal Axis During The Onset Of Puberty In Young Bulls
Renaville, Robert ULg; Devolder, A.; Massart, Serge et al

in Journal of Reproduction and Fertility (1993), 99(2),

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See detailComparison of three metrenperone dosage regimens inhibiting the 5-hydroxytryptamine-induced pulmonary dysfunction in cattle
Linden, Annick ULg; Desmecht, Daniel ULg; Amory, Hélène ULg et al

in Research in Veterinary Science (1993), 55

The effects of a 5-hydroxytryptamine (5-HT) challenge infusion on pulmonary function values were studied in healthy calves, pretreated with varying doses of metrenperone, a selective type 2 serotonergic ... [more ▼]

The effects of a 5-hydroxytryptamine (5-HT) challenge infusion on pulmonary function values were studied in healthy calves, pretreated with varying doses of metrenperone, a selective type 2 serotonergic (5-HT2) antagonist. In the first part of the experiment, the 5-HT challenge was performed 30 minutes after administration of metrenperone at a dose of 0.025 mg kg-1 (group 1, n = 8), 0.050 mg kg-1 (group 2, n = 8) and 0.100 mg kg-1 (group 3, n = 7). In the second part, the 5-HT challenge was performed 12 hours after administration of metrenperone at a dose of 0.050 mg kg-1 (group 4, n = 5) and 0.100 mg kg-1 (group 5, n = 5). None of the three doses of metrenperone influenced the 5-HT-induced ventilatory changes. For the challenge performed 30 minutes after blockade, all three doses inhibited the bronchoconstrictive process triggered by the 5-HT challenge. There was no dose-related inhibition. On the other hand, when the challenge was performed 12 hours after metrenperone, there was a dose-related inhibition with only the higher dose (0.100 mg kg-1) showing a significant efficacy in inhibiting 5-HT-induced bronchoconstriction. It is concluded that, if 5-HT is involved in the pathophysiological processes of respiratory diseases in cattle, a 5-HT2 blockade with metrenperone at a dose rate of 0.100 mg kg-1 and with a dosage interval of 12 hours should improve pulmonary function. [less ▲]

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See detailExteroceptive suppression of temporalis muscle activity in patients with chronic headache and in normal volunteers: methodology, clinical and pathophysiological relevance.
Schoenen, Jean ULg

in Headache (1993), 33(1), 3-17

Exteroceptive suppression of temporalis muscle activity was studied in patients with chronic headache and in healthy controls. Among different methods of recording, averaging 10 full-wave rectified EMG ... [more ▼]

Exteroceptive suppression of temporalis muscle activity was studied in patients with chronic headache and in healthy controls. Among different methods of recording, averaging 10 full-wave rectified EMG responses produces results with acceptable variability and discomfort. The late temporalis exteroceptive suppression period (ES2) is reduced on average in patients with chronic tension-type headache; this finding has been reproduced by several independent laboratories. Mean duration of temporalis ES2 is also diminished, but to a lesser degree, in daily drug abuse headache and, as shown by others, in episodic tension-type headache. It is normal in migraine between attacks, cluster headache and various types of symptomatic headaches. Temporalis ES2 may be decreased in untreated patients with major depression. In healthy volunteers, temporalis ES2 duration is reduced by a short-lasting painful stimulus to peripheral limbs after a delay of 50 to 60 ms, and by a sub-motor threshold electromagnetic stimulation to the contralateral cerebral cortex after a delay of 20 to 30 ms. In contrast, long-lasting trains of peripheral painful stimuli have no effect. Various pharmacological agents are able to modify temporalis ES2. Its duration is increased by 5-HT antagonists, but decreased by 5-HT uptake blockers. Pharmacological effects may differ between controls and patients. Considering these results and available data on the anatomo-functional organization of masticatory reflexes, we postulate that temporalis ES2 is a marker of the excitability of interneuronal nets in the ponto-medullary reticular formation. In chronic tension-type headache, excitability of these interneurons is decreased because of inadequate control by the serotonergic raphe magnus nucleus and the periaqueductal gray matter. Dysfunctioning of the latter structures might be caused by abnormal limbic inputs to the brain stem. Some steps of this pathophysiological hypothesis can be verified by modern neurophysiological techniques. [less ▲]

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See detailLa racine grb et l'Amon-grb
Malaise, Michel ULg; Winand, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1993), 68

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See detailVisite du Trésor de la Cathédrale de Liège
George, Philippe ULg

in Feuillets de la Cathédrale de Liège (1993)

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See detailOptical imaging of the gravitational lens system B 1422+231
Remy; Surdej, Jean ULg; Smette, A. et al

in Astronomy and Astrophysics (1993), 278

Direct optical images (Bessel V, R and Gunn i; average seeing of 0.88 seconds) of B1422+231, obtained in March 1993 at European Southern Observatory (ESO) (La Silla), have been decomposed by fitting ... [more ▼]

Direct optical images (Bessel V, R and Gunn i; average seeing of 0.88 seconds) of B1422+231, obtained in March 1993 at European Southern Observatory (ESO) (La Silla), have been decomposed by fitting multiple Point Spread Functions (PSFs). We detect the optical counterparts of the four known radio point-like components. No additional optical image is found, but due to the compactness of the configuration, our detection limit for additional point sources is rather low (19.3 in R). The deduced positions and photometry of the four optical components agree pretty well with the radio and IR observations and this study provides further evidence supporting the gravitational lens origin of B1422+231. [less ▲]

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See detailA method of comparison of two close batches data: Application to analysis of fog formation causes
Boreux, Jean-Jacques ULg; Guiot, Joël

in Geophysical Research Letters (1993), 20(12), 1179-1182

Given suitable conditions of air temperature and humidity, the density of a fog and its microphysical properties depend mainly on the availability of cloud condensation nuclei (CCN) and their nature. Fogs ... [more ▼]

Given suitable conditions of air temperature and humidity, the density of a fog and its microphysical properties depend mainly on the availability of cloud condensation nuclei (CCN) and their nature. Fogs become particularly dense near certain industrial plants because of high concentration of hygroscopic combustion particles in the air. Their role in dense fog formation is estimated by comparing the local climates and CCN concentrations at two similar sites, the first being more subject to air pollution and dense fogs than the second. Orthogonal regression is applied to three meteorological variables (air temperature, relative humidity, wind speed) and CCN concentration. As we compare very close variables, bootstrap provides precise confidence intervals independent of Gaussian assumptions. Two sites are compared: they are located in the Meuse valley (Belgium) at a distance of about 15 km. We found that the local climate of the polluted site is not only colder and wetter but also richer in CCN that the control site. These results suggest interactions of natural and anthropogenic causes in dense fog formation at industrial site. This method is useful in various domains of geophysics when correlated time series have to be compared. [less ▲]

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See detailProduction of hemicellulase by Penicillium canescens 10-10C. Arch. Int. Phys. Bioch., 101, B1-B00.
Fonder, C.; Rikir, R.; Kvesitadze, G. et al

in Archives Internationales de Physiologie et de Biochimie (1993), 101(B1-B100),

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See detail"Influence of bioreactor aeration conditions on sporulation rate of Bacillus subtilis (b 213 stream)"
Meurisse, E.; Hbid, Ch.; Jacques, Ph. et al

in Mededelingen - Faculteit Landbouwwetenschappen, Rijksuniversiteit Gent (1993), 58(4b), 1985-1987

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See detailRapport préliminaire sur la 2e campagne de fouille à Tell Amarna (Syrie)
Tunca, Önhan ULg

in Akkadica (1993), 83

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See detailL'antiquité classique comme source d'inspiration dans l'oeuvre de Karel Tchapek
Mouton, Charles ULg

in Slavica Gandensia (1993), 20

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See detailEpidural anesthesia and intrathoracic blood volume.
Warner, David O; Brichant, Jean-François ULg; Ritman, Erik L et al

in Anesthesia and Analgesia (1993), 77(1), 135-40

To investigate how epidural anesthesia changes intrathoracic gas volume, high epidural anesthesia was administered to five pentobarbital-anesthetized dogs lying supine, and the total intrathoracic volume ... [more ▼]

To investigate how epidural anesthesia changes intrathoracic gas volume, high epidural anesthesia was administered to five pentobarbital-anesthetized dogs lying supine, and the total intrathoracic volume at end-expiration was measured with a high-speed three-dimensional x-ray scanner. The amount of gas in the lungs at end-expiration [the functional residual capacity (FRC)] was measured with a nitrogen washout technique, and the intrathoracic tissue volume, including the intrathoracic blood volume, was calculated as the difference between intrathoracic volume at end-expiration and FRC. High epidural anesthesia with the local anesthetic etidocaine to a T-1 myotomal level significantly (P < 0.05) increased intrathoracic volume at end-expiration [76 +/- 35 mL (M +/- SD)] by significantly increasing both intrathoracic tissue volume (33 +/- 15 mL) and FRC (43 +/- 26 mL). Increases in intrathoracic tissue volume were probably caused by increases in intrathoracic blood volume. We conclude that increases in FRC caused by epidural anesthesia in anesthetized dogs lying supine may be minimized by a concurrent increase in intrathoracic blood volume. These results suggest that measurements of thoracic gas volume alone may be insufficient to describe chest wall responses to epidural anesthesia. [less ▲]

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See detailConfidence levels of correlations between miospore biohorizons and standard conodont zones during Middle and Late Devonian time.
Streel, Maurice ULg; Loboziak, S

in Newsletter. Subcommission on Devonian Stratigraphy (1993), 10

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See detailAnalgesic Efficiency of Propacetamol Hydrochlorid after Lumbar Disc Surgery
Hans, Pol ULg; Brichant, Jean-François ULg; Bonhomme, Vincent ULg et al

in Acta Anaesthesiologica Belgica (1993), 44(4), 129-33

The influence of intravenous propacetamol hydrochlorid administration on postoperative analgesia and intramuscular opioid consumption was assessed in a randomized placebo-controlled study. Fourty patients ... [more ▼]

The influence of intravenous propacetamol hydrochlorid administration on postoperative analgesia and intramuscular opioid consumption was assessed in a randomized placebo-controlled study. Fourty patients scheduled for lumbar disc surgery were randomly allocated to two groups. They were given either propacetamol 2 g or saline every 6 hours, starting at the end of procedure for a 24 hours period. The pain intensity (VAS) was not significantly different between the two groups except 3 and 4 hours after surgery, where it was higher in the paracetamol group. The cumulative narcotic consumption (piritramide on request) was higher in the placebo group from 6 hours till 9 hours after surgery but not significantly different after 24 hours. Piritramide administration decreased VAS score significantly in both groups while propacetamol reduced it in a significant way only when given from 12 hours after surgery. [less ▲]

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