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See detailLipid-binding properties of synthetic peptide fragments of human apolipoprotein A-II.
Benetollo, C.; Lambert, Géraldine ULg; Talussot, C. et al

in European Journal of Biochemistry (1996), 242(3), 657-64

Human apolipoprotein A-II (apo A-II) consists of three potential amphipathic helices of 17 residues each, which contribute to the lipid-binding properties of this apolipoprotein. The conformation and ... [more ▼]

Human apolipoprotein A-II (apo A-II) consists of three potential amphipathic helices of 17 residues each, which contribute to the lipid-binding properties of this apolipoprotein. The conformation and lipid-binding properties of these peptides, either as single-helix or as two-helix peptides, were investigated by turbidity, fluorescence, electron-microscopy and circular-dichroism measurements, and are compared in this article. The lipid affinity of shorter C-terminal segments of apo A-II was compared with those of the single-helix or two-helix peptides, to define the minimal peptide length required for stable complex formation. The properties of the apo-A-II-(13-48)-peptide were further compared with those of the same segment after deletion of the Ser31 and Pro32 residues, because the deleted apo-A-II-(13-30)-(33-48)-peptide, is predicted to form a long uninterrupted helix. The single helices of apo A-II could not form stable complexes with phospholipids, and the helix-turn-helix segment spanning residues 13-48 was not active either. The apo-A-II-(37-77)-peptide and the apo-A-II-(40-73)-peptide could form complexes with lipids, which appear as discoidal particles by negative-staining electron microscopy. The shortest C-terminal domain of apo A-II able to associate with lipids to form stable complexes was the apo-A-II-(40-73)-peptide, which consisted of the C-terminal helix, a beta-turn and part of the preceding helix. The shorter apo-A-II-(49-77)-peptide, and the helical apo-A-II-(13-30)-(33-48)-peptide, could also associate with phospholipids. The complexes formed were, however, less stable, as they dissociated outside the transition temperature range of the phospholipid. These data suggest that the C-terminal pair of helices of apo A-II, which is the most hydrophobic pair, is responsible for the lipid-binding properties of the entire protein. The N-terminal pair of helices of apo A-II at residues 13-48 does not associate tightly with lipids. The degree of internal similarity and the cooperativity between the helical segments of apo A-II is thus less pronounced than in apo A-I or apo A-IV. The N-terminal and C-terminal domains of apo A-II appear to behave as two distinct entities with regard to lipid-protein association. [less ▲]

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See detailThermographic facial pattern following an alpha2-adrenergic agonist injection in two horses suffering from Horner's syndrome
Ghafir, Y.; Art, Tatiana ULg; Lekeux, Pierre ULg

in Equine Veterinary Education (1996), 8(4), 192-195

The objective of the present study was to confirm this latter assumption, by measuring the facial skin temperature by infrared thermography after administration of an alpha2-adrenergic agonist to horses ... [more ▼]

The objective of the present study was to confirm this latter assumption, by measuring the facial skin temperature by infrared thermography after administration of an alpha2-adrenergic agonist to horses suffering from HS. [less ▲]

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See detailAu fur et à mesure qu'elles se construisent, les trajectoires professionnelles divergent entre les sexes : l'exemple belge
Gavray, Claire ULg

in Formation Emploi : Revue Française de Sciences Sociales (1996), 93

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See detailCompte-rendu de Pascal Engel, Philosophie et psychologie
Leclercq, Bruno ULg

in Revue Philosophique de Louvain (1996), 94

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See detailPrediction of signal peptide functional properties: a study of the orientation and angle of insertion of yeast invertase mutants and human apolipoprotein B signal peptide variants.
Talmud, P.; Lins, Laurence ULg; Brasseur, Robert ULg

in Protein Engineering (1996), 9(4), 317-21

A number of studies have introduced mutations into the yeast invertase signal peptide, using it as a model system to elucidate features for targeting, translocation and intracellular transport. Using ... [more ▼]

A number of studies have introduced mutations into the yeast invertase signal peptide, using it as a model system to elucidate features for targeting, translocation and intracellular transport. Using molecular modelling of the invertase signal peptide we have analysed the hydrophobicity potential and the change in dielectric constant of the energy transfer, when the molecule moves from a hydrophobic to a hydrophilic phase at the simulated hydrophobic-hydrophilic interface. This modelling has been carried out on wild type and mutant invertase signal peptides of altered function, previously reported in the literature. While the predicted angle of insertion correlates with the measured extent of invertase secretion, with an optimum angle of 45 degrees, mutations that change the angle of orientation reduce the extent of invertase secretion. We have applied these same molecular modelling principles to the naturally occurring variants of the human apolipo-protein B (apoB) signal peptide, that confer a secretion defective phenotype when fused to yeast invertase and expressed in yeast. Our modelling thus identifies a strong correlation between the predicted angle of insertion of the signal peptide into the membrane and its ability to direct secretion. [less ▲]

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See detailPrognostic Significance of bcl-2 Protein Expression in Aggressive Non-Hodkin's Lymphoma
Hermine, Olivier; Haioun, Corinne; Lepage, Eric et al

in Blood (1996)

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See detailSensitivity calculations and variance analysis in plant measurement reconciliation
Heyen, Georges ULg; Marechal, Eric; Kalitventzeff, Boris ULg

in Computers & Chemical Engineering (1996), 20(Suppl. A), 539-544

Analysis of the results of a data reconciliation program is made easier by extracting more information from the Jacobian matrix of the constraint equations. Standard deviation for all state variables ... [more ▼]

Analysis of the results of a data reconciliation program is made easier by extracting more information from the Jacobian matrix of the constraint equations. Standard deviation for all state variables (measured or not measured) is related to the standard deviation of measurements. Distinction between variables that are actually corrected by the validation process, and those that are merely derived from a single measurement is straightforward. Based on this information, decisions can be taken : deletion of unnecessary measurements, addition of new measurement points and their optimal selection, or identification of key measurements for which any enhancement of accuracy would result in significant improvement in the quality of the process validation. [less ▲]

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See detailMolecular Evidence That The Whitefly-Transmitted Sweetpotato Mild Mottle Virus Belongs To A Distinct Genus Of The Potyviridae
Colinet, Dominique; Kummert, Jean; Lepoivre, Philippe ULg

in Archives of Virology (1996), 141(1), 125-135

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See detailTomographie a emission de positons dans l'evaluation de l'extension ganglionnaire intrathoracique du cancer bronchique non petites cellules. Etude preliminaire chez 30 patients.
Bury, Thierry ULg; CORHAY, Jean-Louis ULg; Paulus, P et al

in Revue des Maladies Respiratoires (1996), 13(3), 281-286

Current methods for evaluating the mediastinum include chest radiography, computed tomography (CT) or magnetic resonance (MR) imaging and mediastinoscopy. Despite advances in morphologic imaging, some ... [more ▼]

Current methods for evaluating the mediastinum include chest radiography, computed tomography (CT) or magnetic resonance (MR) imaging and mediastinoscopy. Despite advances in morphologic imaging, some lung cancer patients are found to have unresectable disease at surgery. In contrast to CT scan or MR imaging, which depend primarily on anatomic and morphological criteria, positron emission tomography (PET) with 18fluorodeoxyglucose (FDG) depends mainly of the metabolic characteristics of a tissue for the diagnosis of disease. We perform a prospective study to compare FDG-PET and CT of the thorax in the presurgical assessment of the mediastinum in patients with newly diagnosed non-small cell lung cancer. Thirty patients have been included. CT and PET-scans were interpreted separately and results were compared to surgical staging during thoracotomy. In assessing mediastinal involvement, CT scan had a sensitivity of 56% and a specificity of 64%. For diagnosis mediastinal nodal disease, FDG-PET was 87% sensitive and 78% specific. Its positive predictive value was 82%, and the negative value was 83%. In conclusion, our preliminary results show that FDG-PET appears more accurate than CT in staging of mediastinal non-small cell lung cancer. [less ▲]

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See detailExperimental model for the study by chemiluminescence of the activation of isolated equine leucocytes.
Benbarek, H.; Deby, Ginette ULg; Deby, C. et al

in Research in Veterinary Science (1996), 61(1), 59-64

The activation of human polymorphonuclear leucocytes (the respiratory burst) can be studied by measuring their chemiluminescent response. This technique was adapted to equine leucocytes to investigate the ... [more ▼]

The activation of human polymorphonuclear leucocytes (the respiratory burst) can be studied by measuring their chemiluminescent response. This technique was adapted to equine leucocytes to investigate the effects of cell number, activator concentration, enhancers of chemiluminescence, pH, temperature and inhibitors. Leucocytes were isolated from citrated blood from healthy horses and chemiluminescence was measured with a Bio-Orbit luminometer sensitive to 900 nm light. The optimal cell density for the maximal chemiluminescent response ranged from 10(6) to 10(7) leucocytes 600 microliters-1. Chemiluminescence increased as a function of temperature, and the concentrations of luminol, lucigenin and phorbol myristate acetate (PMA), and was pH related (optimal pH value = 8.0 for lucigenin and 8.5 for luminol). The inhibition of chemiluminescence by 5 x 10(-5) M azide was 88 per cent for luminol and 37 per cent for lucigenin. Superoxide dismutase (100 IU) totally inhibited the chemiluminescence response. Approximately 30 per cent variability in chemiluminescence was observed under the same assay conditions, depending on the origin of the leucocytes. Based on these results, the conditions selected for the measurement of equine leucocyte chemiluminescence were: 10(6) to 10(7) leucocytes 600 microliters-1, 1 x 10(-6)M PMA, 1 mM luminol or 0.4 mM lucigenin, physiological pH (7.4) and physiological temperature (37.8 degrees C). These conditions were similar to those used for measuring the chemiluminescent response of human leucocytes. [less ▲]

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See detailUn nouveau département de français à l'Université de Liège : ses précédents, ses missions, ses projets, son équipe
Defays, Jean-Marc ULg

in Français 2000 : Le point sur le Français langue étrangère (1996), (150-151), 60-62

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See detailLe frêne, un bois noble et précieux
Claessens, Hugues ULg

in Forêt Wallonne (1996), 28

Avec le bouleau, l'aulne glutineux, les tilleuls, les érables, le merisier et d'autres feuillus relativement marginaux dans le marché du bois, le frêne fait partie des espèces secondaires de la forêt ... [more ▼]

Avec le bouleau, l'aulne glutineux, les tilleuls, les érables, le merisier et d'autres feuillus relativement marginaux dans le marché du bois, le frêne fait partie des espèces secondaires de la forêt wallonne, qui, ensemble ne représentent que 7% du volume sur pied, alors qu'à eux seuls, le hêtre, les chênes et l'épicéa en totalisent 85% (données IFW). Certaines, comme le frêne, sont qualifiées de "nobles" ou encore de "précieuses" en raison de leur valeur marchande (frêne, érable et merisier). Une des causes de ce phénomène est le choix délibéré des propriétaires forestiers, qui, pour des raisons que nous connaissons, à la fois historiques et liées aux marchés du bois passé et actuel, ont préféré le hêtre, le chêne et l'épicéa, souvent sous forme de monoculture, réduisant ainsi l'espace qui revenait naturellement aux espèces secondaires, naturellement disséminées dans nos forêts. [less ▲]

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See detailDe la spécificité du discours comique
Defays, Jean-Marc ULg

in Français Moderne (Le) (1996), LXIV

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See detailCardiovascular involvement during HIV infection.
Valdes, E. F.; Fernandez, R. E.; Villanueva, H. R. et al

in European Heart Journal (1996), 17(10), 1605

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See detailPseudoaneurisma gigante del ventriculo izquierdo
Olivieri, E.; Guessaghi, R.; Chavin, A. et al

in Prensa Medica Argentina (1996), 83(10), 919-924

A 85 years old patient was hospitalized because of thoracic pain, lasting since three months. He suffered of Parkinson's disease and he was a smoker. The pain increased with cough and Vansalva's test. His ... [more ▼]

A 85 years old patient was hospitalized because of thoracic pain, lasting since three months. He suffered of Parkinson's disease and he was a smoker. The pain increased with cough and Vansalva's test. His left arm was cianotic. An arterial obstruction was suspected. Dopler ultrasound of the left arm confirmed a partial obstruction of the left axillar artery. Surprisingly, thoracic scan and MRI found an important cardiomegaly. The heart was in contact with the diaphragmatic and gastric region. Ecocardiography confirmed a 7 cm pseudo aneurysm of the left ventricle. Coronarography showed extreme hypokinesia of the left ventricle. There was also an obstruction of the right coronary and 50 % stenosis of the left coronary. Pseudo aneurysm was a complication of myocardial infarction of the left ventricle. Surgery was offered to the patient, but he declined the intervention. He was dismissed with medical treatment and anticoagulation. The patient deceased three months later. [less ▲]

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See detailCompte rendu de Le clerc séculier au Moyen Age, Paris, 1993
George, Philippe ULg

in Cahiers de Clio (1996)

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See detailComparaison des effets de différents types de traitement phytosanitaires des semences de cotonnier au Burundi et en Grèce
Carême, C.; Mergeai, Guy ULg; Ydraiou, Francesca et al

in Tropicultura (1996), 14

Les effets de plusieurs matières actives insecticides et de différentes techniques de traitement des semences du cotonnier ont été étudiés lors de 7 essais réalisés au Burundi et en Grèce en 1993 et 1994 ... [more ▼]

Les effets de plusieurs matières actives insecticides et de différentes techniques de traitement des semences du cotonnier ont été étudiés lors de 7 essais réalisés au Burundi et en Grèce en 1993 et 1994. Les essais menés au Burundi mettent en évidence l'efficacité très hautement significative sur Aphis gossypii Glover de l'imidaclopride à la dose de 3g m.a./kg, associé au chlorothalonil à 0,8 g/kg semences, utilisé en enrobage des semences délintées. L'absence de pression parasitaire n'a pas permis de départager les traitements testés en Grèce en ce qui concerne leur efficacité pour lutter contre les ravageurs qui attaquent le cotonnier au début de son cycle. Les observations écophysiologiques réalisées au cours de ces expérimentations mettent en évidence une amélioration significative de la précocité de la maturation des capsules chez les plantes issues de graines enrobées portant une dose moyenne de 2,2 g d'imidaclopride et 2,4 g de TMTO par kg de semences. Le gain de précocité est en moyenne de 10 jours par rapport au traitement témoin. [less ▲]

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See detailRegulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.
De Smedt, T.; Pajak, B.; Muraille, E. et al

in Journal of Experimental Medicine (1996), 184(4), 1413-24

Dendritic cells (DC) are described as "nature's adjuvant," since they have the capacity to sensitize T cells in vivo upon first encounter with the antigen. The potent accessory properties of DC appear to ... [more ▼]

Dendritic cells (DC) are described as "nature's adjuvant," since they have the capacity to sensitize T cells in vivo upon first encounter with the antigen. The potent accessory properties of DC appear to develop sequentially. In particular, the ability to process antigens and to sensitize native T cells develops in sequence, a process termed "maturation" that is well described in vitro. Here, we obtain evidence for maturation in vivo in response to the bacterial product lipopolysaccharide (LPS). Before LPS treatment, many DC are found at the margin between the red and white pulp. These cells lack the M342 and DEC-205 markers, but process soluble proteins effectively. 6 h after LPS, DC with the M342 and DEC-205 markers are found in increased numbers in the T cell areas. These cells have a reduced capacity to process proteins, but show increases in the B7 costimulator and T cell stimulatory capacity. 48 h after LPS, the number of DC in the spleen is reduced markedly. We interpret these findings to mean that LPS can cause DC in the marginal zone to mature and to migrate into and then out of the T cell areas. [less ▲]

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See detailDu gang au groupe social: une analyse socio-préventive
Comeron, Manuel ULg

in Cahiers de la Sécurité (1996)

Au delà d'une enceinte ludique, le stade de football est le théatre d'un supporterisme démonstratif: agressivité des ultra ou hooligan, exaspération partisane, foule. Le supporter est l'objet d'étude de ... [more ▼]

Au delà d'une enceinte ludique, le stade de football est le théatre d'un supporterisme démonstratif: agressivité des ultra ou hooligan, exaspération partisane, foule. Le supporter est l'objet d'étude de la recherche qui évalue aussi les politiques publiques de prévention. [less ▲]

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See detailFaded Dreams - M. Carnoy
Martiniello, Marco ULg

in New Community (1996), 22(3), 547-548

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See detailAvoided resonance overlapping beyond the energy independent formalism. II. Electronic predissociation
Brems, Vincent; Desouter, Michèle ULg; Liévin, Jacques

in Journal of Chemical Physics (1996), 104

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See detailA new HPLC method for the assay of alkaloids in Strychnos nux-vomica and Strychnos ignatii
Gadi Biala, Rose; Tits, Monique ULg; Wauters, Jean-Noël ULg et al

in Fitoterapia (1996), 67(2), 163-165

A reversed-phase high performance liquid chromatographic procedure was developed for the qualitative and quantitative analysis of the alkaloids in S. nux-vomica and S. ignatii.

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See detailTaqi Growth Hormone Gene Polymorphism And Milk Production Traits In Holstein-Friesian Cattle
Falaki, M.; Sneyers, M.; Prandi, A. et al

in Animal Science (1996), 63

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See detailSaint Remacle, évangélisateur en Ardenne (ca. 650). Mythe et réalité
George, Philippe ULg

in Bulletin de l'Institut Historique Belge de Rome (1996), XXXVIII

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See detailFormes pharmaceutiques à libération prolongée en médecine vétérinaire : systèmes à rétention dans le réticulo-rumen = Sustained-released veterinary dosage forms : retention devices in the reticulorumen
Evrard, Brigitte ULg; Delattre, Luc ULg

in STP Pharma Pratiques (1996), 6(6), 479-486

L'industrialisation des productions animales a mis en évidence la nécessité d'éviter des administrations réitérées chez des animaux dont la manipulation est difficile, et de développer des formes à ... [more ▼]

L'industrialisation des productions animales a mis en évidence la nécessité d'éviter des administrations réitérées chez des animaux dont la manipulation est difficile, et de développer des formes à libération contrôlée ou du moins fortement prolongée. L'anatomie particulière du tube digestive des ruminants offre en outre des possibilités inédites pour le développement de tels systèmes thérapeutiques, notamment grâce à la rétention dans le réticulo-rumen. De telles formes ont essentiellement été développées pour l'administration de médicaments antiparasitaires et antibactériens, de suppléments nutritionnels et de promoteurs croissance. Cette revue décrit les applications potentielles de la technologie des formes à libération contrôlée et prolongée en médecine vétérinaire et les différents dispositifs à rétention dans le réticulo-rumen décrits dans la littérature, brevetés ou commercialisés. More intensive methods ofanimal husbandry have revealed the necessity of avoiding repeated administration ofmedication to animals which are difficult to handle and of developing controlled and sustained release dosage forms. The physiological characteristics of the digestive tract of ruminants provide unique opportunity for controlled release technology, especially due to the animal's reticulo-rumen retention ability. The majorareas of application of these controlled and sustained release dosage forms include the delivery of antibiotic and antiparasitic agents, trace nutrients and growth promoting agents. This review describes the potential applications of controlled and sustained release technology in veterinary medicine and the various reticulo-rumen retention devices which are patented, marketed or described in the literature. [less ▲]

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See detailLes canaux potassiques ATP-dépendants et la sécrétion d'insuline: effets du BPDZ 62
Ouedraogo, R.; Pirotte, Bernard ULg; Antoine, M. H. et al

in Journal de Pharmacie de Belgique (1996), 51

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See detailA Simple Model for the Fire Resistance of Axially Loaded Members - Comparison with experimental results
Franssen, Jean-Marc ULg; schleich, Jean-Baptiste; Cajot, Louis-Guy et al

in Journal of Constructional Steel Research (1996), 37

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See detailCloning and Sequencing of the Dnak Locus in Streptomyces Coelicolor A3(2)
Brans, Alain ULg; Loriaux, Axelle; Joris, Bernard ULg et al

in DNA Sequence : The Journal of DNA Sequencing & Mapping (1996), 6(3), 179-84

The dnaK operon of Streptomyces coelicolor A3(2) was cloned by the DNA-probing method using synthetic oligonucleotides designed on the basis of two of the most conserved regions in 30 different DnaK ... [more ▼]

The dnaK operon of Streptomyces coelicolor A3(2) was cloned by the DNA-probing method using synthetic oligonucleotides designed on the basis of two of the most conserved regions in 30 different DnaK proteins (HSP70). The isolated insert-a BamHI 5.6-kb fragment-was sequenced and shown to contain three open-reading frames organized in an operon and coding for proteins analogous to DnaK, GrpE and DnaJ, successively. [less ▲]

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See detailProbing the Surface Molecular Structure in the UPS Spectra of Octadecanethiol and 1-Cyclohexyl-12-dodecanethiol Self-Assembled on Gold
Duwez, Anne-Sophie ULg; Riga, Joseph; Han, Bo-Ying et al

in Journal of Electron Spectroscopy & Related Phenomena (1996), 81

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See detailEtat-providence et efficacité économique
Gathon, Henry-Jean ULg; Pestieau, Pierre ULg

in Revue Française d'Economie (1996), XI, 2(Printemps), 29-44

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See detailA double-blind, three-week study to compare the efficacy and safety of meloxicam 7.5 mg and meloxicam 15 mg in patients with rheumatoid arthritis.
REGINSTER, Jean-Yves ULg; Distel, M.; Bluhmki, E.

in British Journal of Rheumatology (1996), 35(Suppl 1), 17-21

A multicentre, double-blind, randomized study was conducted in patients with rheumatoid arthritis (RA) in order to compare the efficacy and safety of two different doses of meloxicam, a new preferential ... [more ▼]

A multicentre, double-blind, randomized study was conducted in patients with rheumatoid arthritis (RA) in order to compare the efficacy and safety of two different doses of meloxicam, a new preferential cyclooxygenase-2 (COX-2) inhibitor. Four hundred and twenty-three patients were randomized to receive once-daily oral meloxicam 7.5 mg (n = 216) or meloxicam 15 mg (n = 207) for 3 weeks. The Ritchie joint index and pain in the morning were significantly improved versus baseline (P < 0.001) in both groups. There were no significant differences between the effects of each dose with respect to these measures nor with respect to final assessment of global efficacy by the patients. However, the 15 mg dose was associated with a significantly (P < 0.05) better effect on morning stiffness and grip strength. No differences between the doses were observed with regard to the other secondary efficacy parameter (pain at night, body weight and erythrocyte sedimentation rate). Both doses of meloxicam were well tolerated. There were no differences between the doses with respect to global tolerance as assessed by the patient and the patients, 'general condition'. In conclusion, meloxicam at a once-daily dose of either 7.5 or 15 mg is well tolerated and effective in the treatment of patients with RA. [less ▲]

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See detailIn situ demonstration of germinal cell apoptosis during diethylstilbestrol-induced testis regression in adult male syrian hamsters
Nonclercq, D.; Reverse, D.; Toubeau, G. et al

in Biology of Reproduction (1996), 55(6), 1368-1376

Testis regression was induced in male Syrian hamsters by chronic exposure to diethylstilbestrol (DES), an estradiol-1713 agonist. Experimental groups (n = 4-5) were killed at increasing time intervals ... [more ▼]

Testis regression was induced in male Syrian hamsters by chronic exposure to diethylstilbestrol (DES), an estradiol-1713 agonist. Experimental groups (n = 4-5) were killed at increasing time intervals over a period of 6 mo after initiation of treatment. Apoptosis in testes was demonstrated by in situ analysis of DNA fragmentation. Cell proliferation was monitored by immunostaining nuclei of S-phase cells after pulse labeling with 5-bromo-2'-deoxyuridine. Levels of FSH and testosterone, measured by RIA, fell rapidly in DES-treated hamsters. In parallel, testis weight and seminiferous tubule area underwent an 80% decrease during the first 2 wk of DES administration. The composition of seminiferous epithelium was also drastically affected by DES, since it became progressively confined to Sertoli cells, spermatogonia, and spermatocytes. Testis regression was associated with an important increase of apoptosis, which started 3 days after the beginning of DES administration. Apoptosis was still 10- to 50-fold higher than in control testes by the end of treatment; it affected primarily spermatocytes and, to a much lesser extent, spermatogonia. Cell proliferation was not inhibited by chronic DES administration. In conclusion, these data indicate that apoptosis can by itself account for estrogen-induced testis regression. [less ▲]

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See detailMuscle protein metabolism in relation to growth rate in double muscled Belgian Blue bulls: an integrated approach
Van Eenaeme, Christian ULg; Hornick, Jean-Luc ULg; Baldwin, Paule et al

in Mededelingen van de Faculteit van Landbouwwetenschappen, Rijksuniversiteit, Gent (1996), 61/4a

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See detailT92-0045: Interlaboratory quality control on Tpot measurements
Coucke, Philippe ULg; Beer, K.; Bernier, J. et al

in International Journal of Radiation, Oncology, Biology, Physics (1996), 36(1(supp1)), 384

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See detailDéplacements prémigratoire et itinéraire de migration d'une cigogne noire (Cicinia nigra) juvénile suivie par télémétrie satellitaire
Libois, Roland ULg; Jadoul, Gérard

in Aves (1996), 33(1), 1-10

On 19th of July 1995, a juvenile black stork was caught in the vicinity of Bastogne (Province of Luxembourg, Belgium) and was fitted a PTT platform weighing about 75 grams. The locations obtained by the ... [more ▼]

On 19th of July 1995, a juvenile black stork was caught in the vicinity of Bastogne (Province of Luxembourg, Belgium) and was fitted a PTT platform weighing about 75 grams. The locations obtained by the Argos system were sorted according to their precision and the fixes of good quality (A,0,2 or 3 in the Argos classification) were mapped. From the 19th July to the first migration day (28 August at 09h GMT), more than fifty percent of the 109 obtained fixes are located inside a zone of 100 km² (5.65 km radius) centered near the capture point. Moreover, that zone bas been visited nearly every day by the bird. Twenty more percent of the fixes are situated in a wider area of 300 km² (9.77 km radius). That region is covered by spruce plantations, deciduous forests and cattle meadows with numerous small watercourses and several ponds including fish ponds. Some medium distance (10 to 110 km apart from the home range centre) movements were also recorded, mainly eastwards and westwards. No difference has been evidenced in the home range use during the 4 decades of monitoring. The migration travel was monitored till the 06th September, when the transmitter failed due to a technical misconception. At that time, the stork was located in the region of Fès (Morocco). Within 9 days, the bird has travelled a distance of ca 2,400 km (mean daily movement: 237 km). The Pyrenees were crossed in the high valley of the river Tech (Pyrénées Orientales, France) only 3 days after the departure and the bird has been seen by Spanish colleagues when flying across the strait of Gibraltar (Tarifa, 5 September, 07.55 h GMT). [less ▲]

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See detailCuba in tijden van periodo especial
Vanden Berghe, Kristine ULg

in Romaneske (1996), 21(1), 40-44

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See detailThree hTIM mutants that provide new insights on why TIM is a dimer
Mainfroid, Véronique; Terpstra, Peter; Beauregard, Marc et al

in Journal of Molecular Biology (1996), 257(2), 441-56

Human triosephosphate isomerase (hTIM), a dimeric enzyme, was altered by site-directed mutagenesis in order to determine whether it can be dissociated into monomers. Two hTIM mutants were produced, in ... [more ▼]

Human triosephosphate isomerase (hTIM), a dimeric enzyme, was altered by site-directed mutagenesis in order to determine whether it can be dissociated into monomers. Two hTIM mutants were produced, in which a glutamine residue was substituted for either Met14 or Arg98, both of which are interface residuces. These substitutions strongly interfere with TIM subunit association, since these mutant TIMs appear to exist as compact monomers in dynamic equilibrium with dimers. In kinetic studies, the M14Q mutant exhibits significant catalytic activity, while the R98Q enzyme is inactive. The M14Q enzyme is nevertheless much less active than unmutated hTIM. Moreover, its specific activity is concentration dependent, suggesting a dissociation process in which the monomers are inactive. In order to determine the conformational stability of the wild-type and mutant hTIMs, unfolding of all three enzymes was monitored by circular dichroism and tryptophan fluorescence spectroscopy. In each case, protein stability is concentration dependent, and the unfolding reaction is compatible with a two-state model involving the native dimer and unfolded monomers. The conformational stability of hTIM, as estimated according to this model, is 19.3 (+/-0.4) kcal/mol. The M14Q and R98Q replacements significantly reduce enzyme stability, since the free energies of unfolding are 13.8 and 13.5 (+/- 0.3) kcal/mol respectively, for the mutants, A third mutant, in which the M14Q and R98Q replacements are cumulated, behaves like a monomer. The stability of this mutant is not concentration-dependent, and the unfolding reaction is assigned to a transition from a folded monomer to an unfolded monomer. The conformational stability of this double mutant is estimated 2.5 (+/-0.1) kcal/mol. All these data combined suggest that TIM monomers are thermodynamically unstable. This might explain why TIM occurs only as a dimer. [less ▲]

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See detailActualités thérapeutiques dans la thrombocytémie essentielle
Hermanne, J.-P.; Tassin, F.; Beguin, Yves ULg et al

in Médecine et Hygiène (1996), 54

Essential thrombocythemia is a myeloproliferative disorder affecting megakaryocyte and is characterized by frequent thrombotic or hemorrhagic complications. In young patients, the optimal management of ... [more ▼]

Essential thrombocythemia is a myeloproliferative disorder affecting megakaryocyte and is characterized by frequent thrombotic or hemorrhagic complications. In young patients, the optimal management of thrombocythaemia is controversial. Since th relationship of thrombosis and hemorrhage to platelet counts is not demonstrated, ther is no clear inidcation for using drugs capable of lowering platelet counts in young asymptomatic subjects. However, treatment should be offered to patients with a definite high risk of major or life-threatening hemostatic complications. The present paper reviews the incidence and risk factors for thrombotic complications and the use of medications inhibiting platelet production. [less ▲]

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See detailIncidence of Inflammatory Bowel Disease in the Province of Liege (Belgium). La Societe De Gastroenterologie Liegeoise
Latour, Pascale ULg; Belaiche, Jacques ULg; Louis, Edouard ULg et al

in Acta Gastro-Enterologica Belgica (1996), 59(1, Jan-Mar), 3-6

Up to now, as there is no national registry of patients with inflammatory bowel disease (IBD) in Belgium, the study of IBD epidemiology in our country is only possible through institutional or regional ... [more ▼]

Up to now, as there is no national registry of patients with inflammatory bowel disease (IBD) in Belgium, the study of IBD epidemiology in our country is only possible through institutional or regional series. Therefore we conducted a prospective epidemiologic study of IBD in the Province of Liege (1 million inhabitants). METHODS: 29 (out of 47) private and public gastroenterologists completed a standard questionnaire for each patient consulting for the first time with clinical symptoms compatible with IBD between 1/06/1993 and 31/05/1994. RESULTS: During that period 104 cases of IBD were recorded: 56 (54%) Crohn's disease (CD), 36 (35%) ulcerative colitis (UC) including 7 proctitis (19% of UC) and 12 (11%) unclassified colitis. The annual incidence was 5.5 per 100.000 for CD and 3.5 for UC. The sex ratio F/M was 1.7 for CD and 0.7 for UC. The median age at the time of diagnosis was 33.5 yrs for CD and 40 yrs for UC. The highest age specific incidence rate for CD and UC was between 20 and 29 yrs : 13.6 and 6.1, respectively. CONCLUSIONS: This first Belgian prospective study has shown an incidence rate for CD comparable with that seen in north European studies but lower than that seen for UC. These results were similar to those observed in the northern part of France. Belgium appears to be a privileged country to undertake a national register and to study epidemiological aspects of IBD. [less ▲]

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See detailLe Calendrier et son Histoire
Biémont, Emile ULg

in Bulletin de la Classe des Sciences. Académie Royale de Belgique (1996), 6e série(VII), 15-71

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See detailSelection of hammerhead ribozymes for optimum cleavage of interleukin 6 mRNA.
Hendrix, Chris; Anne, J; Joris, Bernard ULg et al

in Biochemical Journal (1996), 314 ( Pt 2)

Four GUC triplets in the coding region of the MRNA of interleukin 6 (IL-6) were examined for their suitabilty to serve as a target for hammerhead ribozome-mediated cleavage. This selection procedure was ... [more ▼]

Four GUC triplets in the coding region of the MRNA of interleukin 6 (IL-6) were examined for their suitabilty to serve as a target for hammerhead ribozome-mediated cleavage. This selection procedure was performed with the intention to downregulate IL-6 production as a potential treatment of those diseases in which IL-6 overexpression is involved. Hammerhead ribozymes and their respective short synthetic substrates (19-mers) were synthesized for these four GUC triplets. Notwithstanding the identical catalytic core sequences, the difference in base composition of the helices involved in substrate binding caused substantial variation in cleavage activity. The cleavage reactions on the 1035 nucleotide IL-6 mRNA transcript revealed that two ribozymes were able to cleave this substrate, showing a decrease in catalytic efficiency to 1/30 and 1/300 of the short substrate. This study indicates that the GUC triplet located at nucleotide 510 of the mRNA of IL-6 is the best site for hammerhead ribozyme-mediated cleavage. We suggest that in future targeting of chemically modified hammerhead ribosomes for cleavage of IL-6 RNA should be directed at this location. [less ▲]

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See detailCompte rendu de l'ouvrage de P. Contamine, Des pouvoirs en France. 1300/1500
Marchandisse, Alain ULg

in Le Moyen Âge (1996), 102

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See detailEthnic Mobilisation, Multiculturalism and the Political Process in two Belgian Cities : Antwerp and Liège
Martiniello, Marco ULg; Blommaert, Jan

in Innovation in Social Sciences Research (1996), 9(1), 51-74

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See detailVérification microbiologiques et sérologiques des donneurs de cornées
Weekers, J. F.; Melin, Pierrette ULg; Lejeune, Tony ULg et al

in Bulletin de la Société Belge d'Ophtalmologie (1996), 260

A study was made during 1994 about microbiological contamination on the donor eyes before enucleation of whole globe. We studied the efficiency of the decontamination method by checking sterility of ... [more ▼]

A study was made during 1994 about microbiological contamination on the donor eyes before enucleation of whole globe. We studied the efficiency of the decontamination method by checking sterility of corneal storage medium after two days. We give results of serological tests on 252 donors. [less ▲]

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See detailBronchopulmonary and Disseminated Granulomatous Disease Associated with Aspergillus Fumigatus and Candida Species Infection in a Golden Retriever
Clercx, Cécile ULg; Mc Entee, Kathleen ULg; Snaps, Frédéric ULg et al

in Journal of the American Animal Hospital Association (1996), 32(2, Mar-Apr), 139-45

A seven-year-old, female golden retriever was referred for a paroxysmal, chronic cough and dyspnea, dysphagia, facial pruritus, anterior uveitis, and deteriorating general condition. A severe, mixed ... [more ▼]

A seven-year-old, female golden retriever was referred for a paroxysmal, chronic cough and dyspnea, dysphagia, facial pruritus, anterior uveitis, and deteriorating general condition. A severe, mixed interstitial and alveolar pattern, with poorly defined amorphous lesions, was seen on thoracic radiographs. Multiple, whitish nodules disseminated on the hyperemic respiratory mucosa were noted on bronchoscopy. Escherichia coli and Aspergillus fumigatus were cultured from the bronchoalveolar lavage. Granulomatous lesions in numerous organs were identified during necropsy, and Aspergillus fumigatus and Candida spp. were cultured from lung and kidney tissues. Microscopic granulomatous lesions were compatible with mycotic infection; however fungal organisms were not observed. [less ▲]

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See detailPrimary Systemic Amyloidosis - A report of 2 cases
Dezfoulian, Bita ULg; Arrese Estrada, Jorge ULg; Fernandez, A. et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (1996), 192

We report 2 cases of primary systemic amyloidosis. A monoclonal gammopathy was confirmed at the postmortem examination of the first patient. An extensive search for evidence of chronic infection ... [more ▼]

We report 2 cases of primary systemic amyloidosis. A monoclonal gammopathy was confirmed at the postmortem examination of the first patient. An extensive search for evidence of chronic infection, inflammation, neoplasms and paraproteinemia was conclusively negative in the other patient. The recognition of cutaneous signs of primary systemic amyloidosis is crucial to insure a rapid management aimed at postponing the fatal issue of the disease. [less ▲]

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See detailEnrico Mattioda, Teorie della tragedia nel settecento, Modena, Mucchi, 1994, 366
Curreri, Luciano ULg

in Franco-Italica (1996), 9

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See detailMicrosatellite mapping of a major determinant of White Heifer Disease: the bovine roan locus
Charlier, Carole ULg; Denys, B.; Belanche, J. I. et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (1996), 7

In the Belgian Blue Cattle breed, coat color variation is mainly under the influence of a single autosomal locus, the roan locus, characterized by a pair of codominant alleles: r + (black) and R (white ... [more ▼]

In the Belgian Blue Cattle breed, coat color variation is mainly under the influence of a single autosomal locus, the roan locus, characterized by a pair of codominant alleles: r + (black) and R (white). Heterozygous r + R animals have intermingled black and white hairs, yielding the ``blue'' phenotype typical of the breed. Major interest for the roan locus stems from its pleiotropic effect on fertility, owing to the critical role of the R allele in the determinism of White Heifer Disease. We describe the linkage mapping of the roan locus to bovine Chromosome (Chr) 5, in the interval between microsatellite markers BPI and AGLA293, with an associated lodscore of 11.2. Moreover, we map a candidate gene, the Steel locus coding for the mast cell growth factor, to bovine Chr 5. [less ▲]

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See detailNouveaux bisphosphonates dans l’ostéoporose : craintes et espoirs
Reginster, Jean-Yves ULg

in Revue du Rhumatisme (1996), 63(7-8), 545-548

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See detailThe existence of an urban underclass in Belgium
Martiniello, Marco ULg

in New Community (1996), 22(4), 655-669

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See detailThe Erythrocyte/Brain Glucose Transporter (Glut1) May Adopt A Two-Channel Transmembrane Alpha/Beta Structure.
Ducarme, P.; Rahman, M.; Lins, Laurence ULg et al

in Journal of Molecular Modeling (1996), 2(2), 27-45

There are two models of topology for the membrane domains of the erythrocyte/brain facilitative glucose transporter, GLUT1. The first is composed of 12 membrane-spanning a-helices, the second of 16 ... [more ▼]

There are two models of topology for the membrane domains of the erythrocyte/brain facilitative glucose transporter, GLUT1. The first is composed of 12 membrane-spanning a-helices, the second of 16 membrane-spanning b-strands. We have used Jähnig’s and Eisenberg’s methods to identify possible transmembrane segments (10 spanning a-helices and 4 b-strands). The topology proposed is more consistent with available experimental data from FTIR, CD and mapping experiment than the previous models . We suggest that GLUT1 might form two channels, one of which is responsible for glucose transport. This agrees with the theoretical and experimental arguments. Finally, an analysis of the mutation periodicity and of the mean hydrophobicity for the GLUT family is provided in order to evaluate the packing of the protein in the membrane. Keywords: [less ▲]

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See detailManifestaciones cardiovasculares en el SIDA
Valdes, E. F.; Rostello, E.; Villanueva, H. R. et al

in Prensa Medica Argentina (1996), 83

Cardiovascular complications in acquired immunodeficiency syndrome. AIDS miocardiopathy has been described since 1983. Physiopathologic events leading to AIDS myocardiopathy are largely unknown: viral ... [more ▼]

Cardiovascular complications in acquired immunodeficiency syndrome. AIDS miocardiopathy has been described since 1983. Physiopathologic events leading to AIDS myocardiopathy are largely unknown: viral miocardiopathy, cytokines induced lesions, nutritional status, microvascular and ischemic miocadiopathy have been suspected. We describe a consecutive series of 50 patients (43 males, 7 women) with HIV infection and severe immunodepression (CD4<200/ml) that had clinical, ECG and echocardiographic evaluation. There were 24 drug addicted patients, 17 homosexual patients, and 10 heterosexuals. Some of these patients had the following opportunistic infections: tuberculosis (n=20), Pneumocystis carinii (n=9), Criptocococis (n=9), oropharyngeal candidosis (n=5), toxoplasmosis (n=5), histoplasmosis (n=1) and Kaposi’s sarcoma (n=2). After clinical evaluation 15/50 patients had some kind of cardiovascular complication: 6 patients had congestive heart failure, 5 patients presented with pericardial effusion, one patient has a reversible cardiac arrest, and one patient had pulmonary valvular endocarditis. After Doppler echocardiographic evaluation (according to the American echocardiography association), we found 20 patients with left ventricular diastolic dysfunction, 9 patients with right ventricular diastolic dysfunction and 6 patients with left ventricular systolic dysfunction. In conclusion, our series found left diastolic dysfunction in nearly 40 % of cases and cardiavasular events (pericarditis, heart congestive failure, arrhythmias) in 26% of cases. Cardiovascular complications have prognostic implications in AIDS and shoul be early detected. Further pathological and immunohistochemical studies are needed to clarify the phyiopathological etiologies in AIDS miocardiopathy. [less ▲]

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See detailUne approche heuristique de l'analyse.
Hauchart, C.; Schneider, Marguerite ULg

in Repères IREM (1996), 25

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See detailEvaluation du rôle préventif des oestroprogestatifs et des thérapeutiques non hormonales dans le cadre de l'ostéoporose postménopausique
Reginster, Jean-Yves ULg

in Journal de Gynécologie, Obstétrique et Biologie de la Reproduction (1996), 25(7), 677-83

Osteoporosis is a medical, social and economical problem for developed countries. Prevention remains the only realistic approach to reduce the burden related to this disorder. Primary prevention of ... [more ▼]

Osteoporosis is a medical, social and economical problem for developed countries. Prevention remains the only realistic approach to reduce the burden related to this disorder. Primary prevention of osteoporosis is based on efforts to reach a maximal peak bone mass at the end of the growth period and, subsequently, at the time of menopause. No pharmacological intervention is considered at this stage. Biologically, hormone replacement therapy induces a correction of the biochemical changes observed in markers of bone remodeling at the time of the menopause. A systematic screening of asymptomatic postmenopausal women followed by the induction of hormonal replacement therapy in high risk subjects appears to be an interesting cost/benefit strategy in terms of reasonable attribution of health resources. Nasal administration of calcitonin fully prevents the trabecular bone loss observed during the first years of menopause. Notwithstanding, the exact dose of nasal calcitonin able to prevent bone loss remains to be fully elucidated. Bisphosphonates inhibit bone resorption. Tiludronate prevents trabecular postmenopausal bone loss. The use of selectif estrogen receptor modulators is based on a possible differential action of these molecules, at the level of the estrogenic receptors, depending of the tissue considered. Several direct inhibitors of osteoclastic resorption are also under development. Their main target is either to prevent the linkage of osteoclasts to the bone matrix or to prevent the acidification of bone matrix required to induce the resorption process. [less ▲]

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See detailCompte rendu de J.-L. LEMAITRE, Le Limousin monastique
George, Philippe ULg

in Moyen Age (Le) (1996)

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See detailGaston Leroux et la dissociation de la matière romanesque
Denis, Benoît ULg

in Tapis-franc. Revue du roman populaire (1996), (7), 56-66

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See detailThe riddle of formycin A insulinotropic action
Malaisse, W. J.; Lebrun, P.; Pirotte, Bernard ULg et al

in Biochemical and Molecular Medicine (1996), 57

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See detailCartes de contrôle : les cartes de Shewhart.
Palm, Rodolphe ULg

in Notes de Statistique et d'Informatique (1996), (2), 41

This note describes the SHEWHART control charts for subgroup means, standard deviation, medians, ranges, proportions of defectives, numbers of defectives and numbers of defects. Minitab and SAS outputs ... [more ▼]

This note describes the SHEWHART control charts for subgroup means, standard deviation, medians, ranges, proportions of defectives, numbers of defectives and numbers of defects. Minitab and SAS outputs are given for all these charts. [less ▲]

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See detailLa nutrition et le couple "mère-enfant"
Hennart, P; Porignon, Denis ULg; Donnen, P

in Académie Royale des Sciences d'Outre-Mer (1996)

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See detailLe chaponnage, une technique qui revient à la mode!
Marlier, Didier ULg; Vindevogel, Henri ULg

in Annales de Médecine Vétérinaire (1996), 140

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See detailEffect Of Propylene Glycol Supplementation Around Parturition On Milk Yield, Reproduction Performance And Some Hormonal And Metabolic Characteristics In Dairy Cows
Formigoni, A.; Cornil, Mc.; Prandi, A. et al

in Journal of Dairy Research (1996), 63(1),

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See detailThe efficacy in vitro and in vivo of bacteriocin against Erwinia amylovora : comparison of biological and chemical control of fire blight
Jabrane, A.; Deckers, T.; Ledoux, L. et al

in Acta Horticulturae (1996), 411

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See detailBrain Levels of Thiamine and Its Phosphate Esters in Friedreich's Ataxia and Spinocerebellar Ataxia Type 1
Bettendorff, Lucien ULg; Mastrogiacomo, Frank; LaMarche, J. et al

in Movement Disorders : Official Journal of the Movement Disorder Society (1996), 11(4), 437-439

Decreased blood and cerebrospinal fluid levels of thiamine have been reported in patients with spinocerebellar ataxia disorders. To determine whether a thiamine deficiency is present in the brain, we ... [more ▼]

Decreased blood and cerebrospinal fluid levels of thiamine have been reported in patients with spinocerebellar ataxia disorders. To determine whether a thiamine deficiency is present in the brain, we measured levels of thiamine and its phosphate esters thiamine monophosphate (TMP) and thiamine diphosphate (TDP), in postmortem cerebellar and cerebral cortices of patients with Friedreich's ataxia (FA) and spinocerebellar ataxia type 1 (SCA1). Brain levels of free (nonphosphorylated) thiamine, TMP, TDP, and total thiamine in FA and SCA1 were, on average, not significantly different from control values. However, a nonsignificant trend was observed for slightly reduced levels of TDP and total thiamine in cerebellar cortex of the SCA1 patients, a finding that might be related to the severe neuronal damage in this brain area. We conclude that in FA, brain thiamine concentrations are normal, whereas in SCA1 the levels are, at most, only slightly reduced. [less ▲]

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See detailCartes de contrôle : combinaison de résultats, données corrélées ou multivariées
Palm, Rodolphe ULg

in Notes de Statistique et d'Informatique (1996), (3), 1-37

This note first describes moving average, exponentially weighted moving average and cumulative sum control charts. Then, control charts for autocorrelated and for multivariate data are examined. Minitab ... [more ▼]

This note first describes moving average, exponentially weighted moving average and cumulative sum control charts. Then, control charts for autocorrelated and for multivariate data are examined. Minitab outputs are given for these control charts. [less ▲]

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See detailLa classification numérique : principes et applications
Palm, Rodolphe ULg

in Notes de Statistique et d'Informatique (1996), (1), 28

The principles of some clustering techniques are described and illustrated by an example. The data consist of chemical contents for 45 types of mineral water.

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See detailEffect of total treatment time on event-free survival in carcinoma of the cervix
Delaloye, J-F; COUCKE, Philippe ULg; Pampallona, S et al

in Gynecologic Oncology (1996), 60

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See detailWhat about lorisk Figo Stage Ia and Ib, G1-G2 endometrial adenocarcinoma ?
Delaloye, J-F; Megalo; COUCKE, Philippe ULg et al

in Radiotherapy & Oncology (1996), 43(Supp 1), 6

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See detailIs IL-6 capable to modify chondrocyte metabolism ?
Henrotin, Yves ULg; Labasse, A; Jaspar, JM et al

in Clinical Rheumatology (1996), 15

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See detailEndometrial laser interstitial hyperthermy: a potential modality for endometrial ablation.
Donnez, Jacques; Polet, Roland; Mathieu, Pierre-Emmanuel et al

in Obstetrics & Gynecology (1996), 87(3), 459-64

This study was undertaken to evaluate the efficacy and safety of an intrauterine device designed for endometrial ablation by Nd-YAG laser interstitial hyperthermy. Eight hysterectomy specimens were ... [more ▼]

This study was undertaken to evaluate the efficacy and safety of an intrauterine device designed for endometrial ablation by Nd-YAG laser interstitial hyperthermy. Eight hysterectomy specimens were treated in vitro with an output power of 30 W for 5 minutes; tissue temperatures, recorded by thermocouples, were plotted to draw time-temperature and time-distance curves. As a preliminary series, ten patients were treated, with the first five subjected to local temperature monitoring; all ten were followed-up for 6-17 months. Immediate and delayed (6 weeks) histologic data were obtained. The intramural temperature at 6 mm from the fibers ranged from 55-60C). In vivo, the cooling effect of the arterial blood flow lowered the serosal temperatures under 41C. The histologic data and the hysterographic pictures suggest that endometrial ablation was effective. This new device does not require distending medium, hysteroscopic control, or high-powered Nd-YAG laser machines. Preliminary long-term results suggest that the device could be used for endometrial ablation. [less ▲]

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See detailLa myxomatose amyxomateuse: isolement de trois souches en Belgique
Marlier, Didier ULg; Vindevogel, Henri ULg

in Annales de Médecine Vétérinaire (1996), 140

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See detailDéveloppement d'un modèle de type arbre appliqué à la croissance des peuplements feuillus irréguliers du sud de la Belgique
Lejeune, Philippe ULg

in Canadian Journal of Forest Research = Journal Canadien de la Recherche Forestière (1996), 26(10), 1838-1848

A model predicting circumference growth of individual trees has been developed for mixed irregular stands dominated by Fagus silvatica L. in southeastern Belgium. This model integrates simultaneously tree ... [more ▼]

A model predicting circumference growth of individual trees has been developed for mixed irregular stands dominated by Fagus silvatica L. in southeastern Belgium. This model integrates simultaneously tree, stand, and growing site characteristics without considering distances between individual trees. It has a determination coefficent of 40.1 % and a residual standard deviation of 0.45cm/year. Forest mensuration variables considered in the model are circumference, tree social position represented by the total basal area of trees greater than the subject tree, stand basal area, and some index of stand structure corresponding to the ratio of the variance over the mean circumference. The site component is essentially expressed by the length of the growing period. The low accuracy obtained for individual tree growth is relative because the results are used mainly after individual trees have been distributed into size classes. We have been able to show that the introduction of crown description in the model can increase its accuracy. But this modification requires a submodel describing crown changes over time. [less ▲]

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See detailType II to type I transformation of chronically stimulated goat latissimus dorsi muscle: a histoenzymological, biochemical, bioenergetic, and functional study.
Radermacker, M. A.; Focant, B.; Hautecler, T. et al

in European Surgical Research = Europäische Chirurgische Forschung = Recherches Chirurgicales Européennes (1996), 28

Five goat latissimus dorsi muscles (LDM) were submitted to a progressive chronic electrostimulation program to reach an integrated understanding of the fast-to-slow transformation process in large mammals ... [more ▼]

Five goat latissimus dorsi muscles (LDM) were submitted to a progressive chronic electrostimulation program to reach an integrated understanding of the fast-to-slow transformation process in large mammals. LDM were regularly sampled and followed during a period of 8 months. Each sample was simultaneously assessed for histoenzymological study, myosin and LDH isoforms and bioenergetic capacities [NADH dehydrogenase cytochrome c oxidoreductase (NADH Cyt c OR), succinate dehydrogenase cytochrome c oxidoreductase (Succ Cyt c OR), cytochrome c oxidase (Cyt c Ox) and LDH]. Such muscles were also tested with and without completion of II to I transformation for their mechanical properties in isometric and isotonic strain gauge testing. The conversion of fast-to-slow myosin monitored by heavy chain (HC I) and light chain slow component (LC2s) began a few days after stimulation and was almost 100% after 100 days. The H-LDH isoforms evolved similarly but did not reach 100% conversion after 200 days. The activity of respiratory chain oxidases increased within 36 h but to a variable extent and peaked after 32 days, corresponding to a 75% transformation of myosin compared to initial levels. NADH Cyt c OR, Succ Cyt c OR, and Cyt c Ox, respectively increased 10-, 5- and 5-fold. These activities then significantly decreased before the completion of the myofibrillar transformation and reached a plateau with stable activities that remained 2- to 3-fold higher than the unstimulated LDM. LDH activity sharply decreased until day 62 (5-fold) and then plateaued. Functionally, muscle showed a reduced speed of contraction and moderate reduction in power output but had become fatigue-resistant. This study documents the transformation process in large mammals and suggests the dynamic relation between workload, aerobic-anaerobic metabolism and the contractile myofibrillar system. [less ▲]

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See detailAgriculture et environnement : pour une sociologie des dispositifs
Mormont, Marc ULg

in Economie Rurale (1996), (No. 236), 28-36

An analytical model for the environmental regulation of agriculture under various aspects, such as the definition of environment, type of agricultural practice, incentives, scale of application and mode ... [more ▼]

An analytical model for the environmental regulation of agriculture under various aspects, such as the definition of environment, type of agricultural practice, incentives, scale of application and mode of administration, is presented. In a number of cases, technical, scientific, social and economic factors also have to be addressed (especially as regards the notion of uncertainty), which entails taking into account a series of heterogeneous and less obvious aspects. A new typology of institutional settings is therefore drawn up, which emphasizes the constraints present in any regulation. Particular reference is made to the EU. [less ▲]

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See detailA Morphometric and Functional Study of the Toxicity of Atmospheric Ammonia in the Extrathoracic Airways in Pigs
Urbain, B.; Gustin, Pascal ULg; Charlier, G. et al

in Veterinary Research Communications (1996), 20(4), 381-399

The effects of atmospheric ammonia (NH3) on the nasal and tracheal mucosa of pigs were investigated by morphometric and functional methods. Pigs were exposed to four concentrations of NH3 [5 (control), 25 ... [more ▼]

The effects of atmospheric ammonia (NH3) on the nasal and tracheal mucosa of pigs were investigated by morphometric and functional methods. Pigs were exposed to four concentrations of NH3 [5 (control), 25, 50 and 100 ppm] for 6 days in a specially designed air-pollutant exposure chamber. Samples were taken from the turbinates and the trachea, and the respiratory mucosa was examined by light and scanning electron microscopy. Dose-response curves to carbachol and isoproterenol were constructed using isolated strips of tracheal smooth muscle, with or without epithelium. In pigs exposed to ammonia, considerable mucosal injuries were observed in the turbinates but not in the trachea. The number of neutrophils in the epithelial layer and in the lamina propria, and epithelial hyperplasia were closely and significantly correlated with the concentrations of ammonia (r = 0.894, p < 0.001; r = 0.727, P < 0.001; and r = 0.818, p < 0.001, respectively). Except for the lamina propria, all these changes were significant (p < 0.05) at ammonia concentrations as low as 25 ppm. The percentage of the surface of the turbinate mucosa that was ciliated tended to decrease with increasing ammonia concentration (r = 0.439, p < 0.082). Ammonia induced smooth-muscle hyperresponsiveness to carbachol with a close linear correlation between individual values of the carbachol-induced maximal effect and the NH3 concentrations (r = 0.526, p < 0.003). While mechanical destruction of the epithelium induced an increase in Emax in the control group, no difference was observed between the intact and denuded strips from animals exposed to ammonia. The response to isoproterenol was not influenced by ammonia. It was concluded that quantitative histological analysis of the inflammatory infiltration and epithelial hyperplasia in the turbinates is a useful tool for quantifying the effects of atmospheric pollutants in pigs; a 6-day exposure to ammonia induces nasal irritation and functional disturbances of the tracheal smooth-muscle contractions at concentrations as low as 25 ppm [less ▲]

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See detailMinority Rights in Europe de H. Miall (ed)
Martiniello, Marco ULg

in Ethnic and Racial Studies (1996), 19(2), 446-447

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See detailTheory of laser-induced two-step electron-ion recombination
Schlagheck, Peter ULg; Maragakis, P.; Lambropoulos, P.

in Zeitschrift für Physik. D, Atoms, Molecules, and Clusters (1996), 37(1), 19-27

A theoretical framework for the quantitative interpretation of laser-induced electron-ion recombination is presented in terms of the density matrix taking into account stochastic bandwidth and pulse ... [more ▼]

A theoretical framework for the quantitative interpretation of laser-induced electron-ion recombination is presented in terms of the density matrix taking into account stochastic bandwidth and pulse duration of the laser. The theory deals with recombination induced from the continuum into one group of states by one laser and further stabilized into a lower group of states by a second laser. Rate equations are then derived from the complete density matrix, and the conditions for their validity are discussed. Both density matrix and rate equations are applied to the interpretation of a recent experiment with equally good agreement. [less ▲]

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See detailLes maladies virales chez le lapin européen (Oryctolagus cuniculus)
Marlier, Didier ULg; Vindevogel, Henri ULg

in Annales de Médecine Vétérinaire (1996), 140

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See detailMorphometric, immunohistological and three-dimensional evaluation of the endometrium of menopausal women treated by oestrogen and Crinone, a new slow-release vaginal progesterone.
Casanas-Roux, Françoise; NISOLLE, Michelle ULg; Marbaix, Etienne et al

in Human Reproduction (1996), 11(2), 357-63

Recently advanced computerized technology was applied to the investigation of morphometric, immunohistological and three-dimensional changes of the endometrial mucosa in order to evaluate quantitatively ... [more ▼]

Recently advanced computerized technology was applied to the investigation of morphometric, immunohistological and three-dimensional changes of the endometrial mucosa in order to evaluate quantitatively the effects of three doses of a new slow-release vaginal progesterone on the endometrium in post-menopausal women. A total of 20 menopausal women, deprived of ovarian function, were given oestrogen for 12 days and a combined therapy of oestrogen (administered orally) and progesterone for another 12 day period. Progesterone was administered vaginally through a new gel (Crinone) utilizing a bioadhesive, biocompatible polymer as a base to achieve a sustained release effect. An endometrial biopsy was taken before treatment, after oestrogen-only treatment and after the oestro-progestogen therapy. Before treatment, all the patients exhibited an atrophic endometrium. After oestrogen-only treatment, typical proliferative changes occurred: an increase in the endometrium thickness, an increase in the mitotic index, numerous cylinder-like glands and no coiled glands, and high concentrations of oestrogen receptors (ER) and progesterone receptors (PR). After the oestro-progestogen therapy, whatever the dose of progesterone given, a secretory transformation of the endometrial mucosa occurred, mitotic activity decreased significantly, more ramified and coiled glands were observed, and a decrease in PR content was noted in epithelial and stromal nuclei, and a decrease in PR content was also observed in epithelial nuclei but not in stromal nuclei. Accurate new techniques of image analysis have shown that crinone therapy could eliminate the proliferative effects of oestrogen treatment in post-menopausal women, despite doses as low as 45 mg of progesterone administered vaginally every other day. The results suggest that the sustained release effects of Crinone are clinically relevant. [less ▲]

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See detailL’immigration. De l’homme seul à la famille de A. Zerhaoui
Martiniello, Marco ULg

in Revue Européenne des Migrations Internationales (1996), 12(1), 224-225

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See detailRéactions physiologiques face à des conditions extrêmes de chaleur et d'humidité relative. Etude de la récupération après l'exercice
Art, Tatiana ULg; Votion, Dominique ULg; Lekeux, Pierre ULg

in Pratique Vétérinaire Equine (1996), 28

The purpose of this study was to follow the recovery of horses during 1hour after treadmill exercise performed either in temperated atmospheric conditions (TC) (ambient temperature: 15°C; relative ... [more ▼]

The purpose of this study was to follow the recovery of horses during 1hour after treadmill exercise performed either in temperated atmospheric conditions (TC) (ambient temperature: 15°C; relative humidity: 55%) or in hot and humid conditions (HHC) (ambient temperature: 30°C; relative humidity: 75%). Five healthy fit standardbred horses (493± 14 kg; 4± 0,5 yrs) were investigated twice at eight days interval, in TC and in HHC. Some ventilatory and cardiorespiratory measurements were made during a standardised treadmill exercise test (SET), other measurements, i.e. cardiac and respiratory frequencies and rectal temperature, during a 1-hour recovery period. The SET consisted in 8 min warm-up and in 8 min exercise (1 min at 1,7, 4, 7, 8, 9 and 10 m/sec and 2 min at 4 m/sec with a 6% (3.4°) slope). Venous blond was sampled before, 2 min, 60 min and 48 hours after the completion of the test for biochemical analysis, namely plasma electrolytes and enzymatic activities. Exercising in HHC induced a reduction of the aerobic metabolism to the total energy requierement, i.e. a 20 % decrease of VO, and 55 % increase in lactate, as well as a decrease in VE. The increase in rectal and skip temperature, the dehydration and the weight loss were higher in HHC than in TC. During the recovery period the HR and f remained higher up to 30 minutes after the end of the SET in HHC while the rectal temperature remained higher up to 60 min after the end of this test. Sa, despite the fact that our horses recovered in TC after exercising in HHC, there were significant differences between their physiological parameters measured during the recovery. This means that the recovery in air-conditionned unit would probably be an insufficient measure to ensure an adequate cooling of the horses and justify consequently the adaptations proposed by the FEI, i.e. the decrease of the distance of the run and the increase of the lime devoted to the hall between phases [less ▲]

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See detailComparison of food conversion by the Pirapatinga Piaractus brachypomus under different times of feeding
Baras, E.; Mélard, Charles ULg; Grignard, J. C. et al

in Progressive Fish-Culturist (1996), 58

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See detailEtude des groupements de macrophytes vasculaires aquatiques de la Semois en rapport avec la qualité globale des eaux et du milieu
Thoen, Daniel ULg; Roussel, Laurence; Nicolas, Jacques ULg

in Ecologie (1996), 27(4), 223-232

Les groupements de macrophytes aquatiques de la Semois (ca. 200 km de long) ont été décrits par l'analyse de 218 relevés de végétation réalisés durant l'année 1994. De l'amont vers l'aval, six groupements ... [more ▼]

Les groupements de macrophytes aquatiques de la Semois (ca. 200 km de long) ont été décrits par l'analyse de 218 relevés de végétation réalisés durant l'année 1994. De l'amont vers l'aval, six groupements végétaux ont été caractérisés. Deux zones principales peuvent être distinguées. Dans la zone amont, la végétation potentielle a été détruite ou remplacée par des groupements végétaux, plus résistants à la pollution organique et aux modifications physiques du milieu: groupement à Sparganium emersum et Potamogeton nanans; association à Potamogeton pectinatus. Dans la zone aval, la présence de groupements relevant du Ranunculetum fluitantis est plus conforme à la végétation potentielle et indique de meilleures conditions du milieu. Une analyse canonique des correspondances, sur les principales espèces aquatiques et les paramètres physico-chimiques de l'eau de 40 stations, a permis de regrouper des espèces présentant des affinités écologiques entre elles et de dégager leurs valeurs indicatrices relatives pour certains paramètres abiotiques. [less ▲]

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See detailParadoxical Sleep Deprivation Increases the Content of Glutamate and Glutamine in Rat Cerebral Cortex
Bettendorff, Lucien ULg; Sallanon-Moulin, M.; Touret, Monique et al

in Sleep (1996), 19(1), 65-71

We investigated the influence of the sleep/waking cycle, the effects of paradoxical sleep deprivation (PSD) and of the vigilance-promoting drug modafinil on the amino acid contents of rat brain cortex. No ... [more ▼]

We investigated the influence of the sleep/waking cycle, the effects of paradoxical sleep deprivation (PSD) and of the vigilance-promoting drug modafinil on the amino acid contents of rat brain cortex. No significant nycthemeral variations in amino acid levels could be detected. PSD (12-24 hours), using the water tank method, significantly increased the levels of glutamate and glutamine. The increase was still observed after the sleep rebound period. gamma-Aminobutyric acid (GABA) levels did not change significantly during the instrumental sleep deprivation but increased during the rebound period. Control experiments indicate that the increase in glutamate and glutamine levels is due to PSD rather than to the stress associated with the experimental procedure. The increase in glutamate content cannot arise only from transamination reactions, because the levels of other amino acids (such as aspartate) did not decrease. Modafinil treatment did not significantly modify the brain cortex content of any of the amino acids tested. [less ▲]

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See detailThe ovarian follicle in cow: in vivo growth and in vitro culture
Beckers, Jean-François ULg; Drion, Pierre ULg; Figueiredo, J. R. et al

in Reproduction in Domestic Animals (1996), 31

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See detailPrécarité psycho-sociale différentielle des hommes et des femmes
Born, Michel ULg; Gavray, Claire ULg

in Cahiers de l'IPSA (1996), 19

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See detail9-Methoxygeissoschizol, an alkaloid from bark of strychnos guianensis
Mavar-Manga, Hélène; Quetin-Leclercq, Joëlle; Llabres, Gabriel ULg et al

in Phytochemistry (1996), 43(5), 1125-1127

The isolation and structure determination of 9-methoxygeissoschizol from the stem bark of Strychnos guianensis is described. Elucidation of its structure is mainly based on NMR studies.

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See detailL’ostéomalacie : étiologie, clinique, physiopathologie et thérapeutique
Reginster, Jean-Yves ULg

in Le Monde Médical de la Femme (1996), 330(23), 18-21

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See detailIdentification of antigens recognized in the developing mouse brain by the RC2 antibody, a marker of radial glia
Leprince, Pierre ULg; Chanas-Sacre, G.; Wattiez, R. et al

in International Journal of Developmental Neuroscience (1996), 14(Sup. 1), 84

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See detailBacteriogical evidence of leptospira infetion in wild mammals from Azores archipelago, Portugal (short report)
Collares Pereira, Margarida; Santos Reis, Margarida; Oom, Maria do Mar et al

in Vie et milieu (1996), 46(3-4), 380-381

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