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See detailDavid Malouf's 'Voyaging Imagination': The Conversations at Curlow Creek
Maes-Jelinek, Hena ULg

in Commonwealth : Essays and Studies (2000), 23(1), 89-98

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See detailLes composantes d'un management efficace dans le cadre des organisations sportives
Cloes, Marc ULg

in Sport (2000), 172

L'objectif de cet article consiste à réaliser une synthèse des notions abordées par les auteurs du colloque "Initiatives en matière de management du sport" et de fournir un outil permettant aux ... [more ▼]

L'objectif de cet article consiste à réaliser une synthèse des notions abordées par les auteurs du colloque "Initiatives en matière de management du sport" et de fournir un outil permettant aux responsables d'organisatons sportives de s'engager dans une auto-analyse des structures dont ils ont la charge. Pour rappel, le management se définit comme l'action de gérer, de diriger, d'assurer le succès d'une organisation. [less ▲]

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See detailDynamics and three-dimensional localization of ribosomal RNA within the nucleolus.
Thiry, Marc ULg; Cheutin, T.; O'Donohue, M. F. et al

in RNA (New York, N.Y.) (2000), 6(12), 1750-61

Although rRNA synthesis, maturation, and assembly into preribosomal particles occur within the nucleolus, the route taken by pre-rRNAs from their synthetic sites toward the cytoplasm remains largely ... [more ▼]

Although rRNA synthesis, maturation, and assembly into preribosomal particles occur within the nucleolus, the route taken by pre-rRNAs from their synthetic sites toward the cytoplasm remains largely unexplored. Here, we employed a nondestructive method for the incorporation of BrUTP into the RNA of living cells. By using pulse-chase experiments, three-dimensional image reconstructions of confocal optical sections, and electron microscopy analysis of ultrathin sections, we were able to describe topological and spatial dynamics of rRNAs within the nucleolus. We identified the precise location and the volumic organization of four typical subdomains, in which rRNAs are successively moving towards the nucleolar periphery during their synthesis and processing steps. The incorporation of BrUTP takes place simultaneously within several tiny spheres, centered on the fibrillar centers. Then, the structures containing the newly synthesized RNAs enlarge and appear as compact ringlets disposed around the fibrillar centers. Later, they form hollow spheres surrounding the latter components and begin to fuse together. Finally, these structures widen and form large rings reaching the limits of the nucleoli. These results clearly show that the transport of pre-rRNAs within the nucleolus does not occur randomly, but appears as a radial flow starting from the fibrillar centers that form concentric rings, which finally fuse together as they progress toward the nucleolar periphery. [less ▲]

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See detailUnimolecular reaction dynamics from kinetic energy release distributions. VI. Energy-selected ions
Lorquet, Jean-Claude ULg

in International Journal of Mass Spectrometry (2000), 201(1-3), 59-67

The kinetic energy distribution (KERD) determined by Brand et al. [Chem. Phys. 76 (1983) 111] for the iodine loss from energy-selected iodopropane ions has been analyzed by the maximum entropy method. The ... [more ▼]

The kinetic energy distribution (KERD) determined by Brand et al. [Chem. Phys. 76 (1983) 111] for the iodine loss from energy-selected iodopropane ions has been analyzed by the maximum entropy method. The entropy deficiency DS has been determined and the value of e(-DS), which measures the efficiency of phase-space sampling, has been found equal to about 96%, thus corresponding to a nearly fully statistical situation. The phase space theory of Klots describes a slightly more constrained situation with e(-DS) ≃ 77%. A rapid determination of the sampled fraction of phase space is possible from energy-selected KERDs, based on the fact that there exists a direct relationship between the efficiency e(-DS) and the reduced maximum of the KERD ε(red)/(M) = ε(M) (E)/<ε>(E). The product ε(M)(E) P(ε(M)/E) or ε(red)/(M) P(ε(red)/(M)) holds the same property. (C) 2000 Elsevier Science B.V. [less ▲]

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See detailContribution à la connaissance des Chrysopidae de Belgique : bilan des captures réalisées à Gembloux.
Mignon, Jacques ULg; Bozsik, Andras; Gaspar, Charles

in Notes Fauniques de Gembloux (2000), 41

Douze espèces de Chrysopidae furent identifiées: H. elegans, N. flava, N. pallida, Ch. ciliata, Ch. perla, Ch. pallens, D. flavifrons, D. prasina, D. ventralis, T. gracilis, Ch. carnea et C. albolineata ... [more ▼]

Douze espèces de Chrysopidae furent identifiées: H. elegans, N. flava, N. pallida, Ch. ciliata, Ch. perla, Ch. pallens, D. flavifrons, D. prasina, D. ventralis, T. gracilis, Ch. carnea et C. albolineata. Une espèce, Tjederina ventralis est nouvelle pour la faune belge. [less ▲]

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See detailSynthesis of new hydrophilic γ-substituted poly(ε-caprolactone)s
Lecomte, Philippe ULg; D'aloia, Violetta; Mazza, Michaël et al

in Polymer Preprints (2000), 41(2), 1534-1535

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See detailProbing Organization and Structural Characteristics of Alkanethiols Adsorbed on Gold and of Model Alkane Compounds through their Valence Electronic Structure: an Ultraviolet Photoelectron Spectroscopy Study
Duwez, Anne-Sophie ULg; Pfister-Guillouzo, G.; Delhalle, Joseph et al

in Journal of Physical Chemistry B (2000), 104

In this paper we report an ultraviolet photoelectron spectroscopy (UPS) study of saturated alkane chains in various configurations and conformations. The dependence of the valence spectra on molecular ... [more ▼]

In this paper we report an ultraviolet photoelectron spectroscopy (UPS) study of saturated alkane chains in various configurations and conformations. The dependence of the valence spectra on molecular structure characteristics has been assessed by comparing the results obtained from n-alkanethiol, R,ö-alkanedithiol, and R-cycloalkyl-ö-alkanethiol monolayers adsorbed on gold, and from gas-phase model alkane compounds. The differences between the spectra reflect directly the structural changes induced in the electronic structure of the alkane chains. We have determined the type of folding sequences adopted in a 1,12-dodecanedithiol monolayer. Angular dependent measurements and investigations on the photoelectron attenuation length have evidenced very fine structural differences between films obtained on deposited gold films, annealed gold films, and gold single crystals [less ▲]

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See detailEffectuer l'état des lieux, la réactivation et la rémédiation des bases de chimie à la charnière entre l'enseignement secondaire et l'Université sur http://www.ulg.ac.be/grptrans/
Müller, Robert; Cornélis, André; Cahay, René et al

in Bulletin de l'Association Belge des Professeurs de Physique et de Chimie (2000), (144), 30-40

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See detailMicroscopic model of ferroelectricity in stress-free PbTiO3 ultrathin films
Ghosez, Philippe ULg; Rabe, K. M.

in Applied Physics Letters (2000), 76(19), 2767-2769

The ground-state polarization of PbTiO3 thin films is studied using a microscopic effective Hamiltonian with parameters obtained from first-principles calculations. Under short-circuit electrical boundary ... [more ▼]

The ground-state polarization of PbTiO3 thin films is studied using a microscopic effective Hamiltonian with parameters obtained from first-principles calculations. Under short-circuit electrical boundary conditions, (001) films with thickness as low as three unit cells are found to have a perpendicularly polarized ferroelectric ground state with significant enhancement of the polarization at the surface. (C) 2000 American Institute of Physics. [S0003- 6951(00)02119-7]. [less ▲]

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See detailEntre stalle et prie-Dieu. La religieuse liégeoise en prière
Henneau, Marie-Elisabeth ULg

in Revue de l'Histoire des Religions (2000), 217(3), 327-344

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See detailICPC-2-E: the electronic version of ICPC-2. Differences from the printed version and the consequences.
Okkes, I.; Jamoulle, Marc ULg; Lamberts, H. et al

in Family practice (2000), 17(2), 101-7

BACKGROUND: In 1998, ICPC-2 was published as a book. In the process of translating the book, and preparing an electronic version of chapter 10 (the actual classification), ICPC-2 proved to contain many ... [more ▼]

BACKGROUND: In 1998, ICPC-2 was published as a book. In the process of translating the book, and preparing an electronic version of chapter 10 (the actual classification), ICPC-2 proved to contain many errors and inconsistencies. Particularly, major problems were identified in the conversion between ICPC-2 and ICD-10, which could lead to major errors when used in electronic patient records. OBJECTIVES: We prepared an electronic version of chapter 10 of ICPC-2, ICPC-2-E, with all necessary corrections, to be published on the Oxford University Press web site as a part of this article. METHODS: Errors and inconsistencies were redressed, including particularly those in the con-version structure with all consequences on the level of inclusion and exclusion criteria, through a process of careful checking. RESULTS AND CONCLUSION: ICPC-2-E, the electronic version of chapter 10 of ICPC-2, is specifically to be used in an electronic patient record and for research purposes. It is to be used together with the first nine chapters of ICPC-2, since the book is indispensable to make a correct use of ICPC. [less ▲]

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See detailLa néosporose chez la chèvre : résultats de deux enquêtes sérologiques dans l'Ouest de la France
Chartier, C.; Baudry, C.; Losson, Bertrand ULg et al

in Point Vétérinaire (2000), 31

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See detailPolymer-layered silicate nanocomposites: preparation, properties and uses of a new class of materials
Alexandre, Michaël ULg; Dubois, Philippe ULg

in Materials Science & Engineering. R: Reports (2000), R28(1-2), 1-63

A review with 115 refs. This review aims at reporting on very recent developments in syntheses, properties and (future) applications of polymer-layered silicate nanocomposites. This new type of materials ... [more ▼]

A review with 115 refs. This review aims at reporting on very recent developments in syntheses, properties and (future) applications of polymer-layered silicate nanocomposites. This new type of materials, based on smectite clays usually rendered hydrophobic through ionic exchange of the sodium interlayer cation with an onium cation, may be prepd. via various synthetic routes comprising exfoliation adsorption, in situ intercalative polymn. and melt intercalation. The whole range of polymer matrixes is covered, i.e., thermoplastics, thermosets and elastomers. Two types of structure may be obtained, namely intercalated nanocomposites where the polymer chains are sandwiched in between silicate layers and exfoliated nanocomposites where the sepd., individual silicate layers are more or less uniformly dispersed in the polymer matrix. This new family of materials exhibits enhanced properties at very low filler level, usually inferior to 5 wt.%, such as increased Young's modulus and storage modulus, increase in thermal stability and gas barrier properties and good flame retardancy. [on SciFinder (R)] [less ▲]

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See detailRepeatability of Doppler ultrasound measurements of hindlimb blood flow in halothane anaesthetised horses
Raisis, Anthea L; Young, L. E.; Meire, H. et al

in Equine Veterinary Journal (2000), 32(3), 239-246

The purpose of this study was to determine the repeatability of femoral blood flow recorded using Doppler ultrasound in anaesthetised horses. Doppler ultrasound of the femoral artery and vein was ... [more ▼]

The purpose of this study was to determine the repeatability of femoral blood flow recorded using Doppler ultrasound in anaesthetised horses. Doppler ultrasound of the femoral artery and vein was performed in 6 horses anaesthetised with halothane and positioned in left lateral recumbency. Velocity spectra, recorded using low pulse repetition frequency, were used to calculate time-averaged mean velocity (TAV), velocity of component a (TaVa), velocity of component b (TaVb), volumetric flow, early diastolic deceleration slope (EDDS) and pulsatility index (PI). Within-patient variability was determined for sequential Doppler measurements recorded during a single standardised anaesthetic episode. Within-patient variability was also determined for Doppler and cardiovascular measurements recorded during 4 separate standardised anaesthetic episodes performed at intervals of at least one month. Within-patient variation during a single anaesthetic episode was small. Coefficients of variation (cv) were <12.5% for arterial measurements and <17% for venous measurements. Intraclass correlation coefficient was >0.75 for all measurements. No significant change was observed in measurements of cardiovascular function suggesting that within-patient variation observed during a single anaesthetic episode was due to measurement error. In contrast, within-patient variation during 4 separate anaesthetic episodes was marked (cv>17%) for most Doppler measurements obtained from arteries and veins. Variation in measurements of cardiovascular function were marked (cv>20%), suggesting that there is marked biological variation in central and peripheral observed. Further studies are warranted to determine the ability of this technique to detect differences in blood flow during administration of different anaesthetic agents [less ▲]

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See detailHistory is a fiction. Quentin Legrand talks with Johan Muyle and CarlHavelange
Havelange, Carl ULg

in Janus. Magazine on art and culture (2000), 2000(4), 7-13

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See detailD'un procès à l'autre - pour une esthétique des médias
Servais, Christine ULg

in Recherches en Communication (2000), 13

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See detailRole Of Surface Chemical Signals In Egg Cannibalism And Intraguild Predation In Ladybirds (Coleoptera : Coccinellidae)
Hemptinne, Jl.; Lognay, Georges ULg; Gauthier, Carole ULg et al

in Chemoecology (2000), 10(3), 123-128

The eggs of some ladybirds are known to be toxic to intraguild ladybird predators. However, this defence is of little value if the eggs are killed before their toxicity becomes apparent. The results ... [more ▼]

The eggs of some ladybirds are known to be toxic to intraguild ladybird predators. However, this defence is of little value if the eggs are killed before their toxicity becomes apparent. The results presented in this paper indicate that chemicals on the surface of the eggs of two species of ladybirds signal the relative risk of cannibalism and intraguild predation. In Adalia bipunctata and Coccinella septempunctata, 87% of the chemicals are alkanes. Each species of ladybird is less reluctant to eat their own eggs than those of the other species. This asymmetry is to be expected because there is a greater risk to ladybirds from intraguild predation than cannibalism. Similar alkanes to those on the surface of the eggs of A. bipunctata are present in tracks left by larvae and on the elytra of the adults of this species. Those in the larval tracks deter females from ovipositing in patches of prey already being attacked by their larvae and those on the elytra are used in mate recognition. That different context dependent messages could be signalled by similar chemicals is an example of semiochemical parsimony. [less ▲]

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See detailLégislation et exercice de l'entomologie en Région wallonne
Fagot, Jean ULg; Dethier, Michel ULg

in Notes Fauniques de Gembloux (2000), 41

In Wallonia, a new law is in study to set up a better level of protection for the fauna and the flora, and that, in respect of the european spirit of Nature preservation. On the other hand, a lot of ... [more ▼]

In Wallonia, a new law is in study to set up a better level of protection for the fauna and the flora, and that, in respect of the european spirit of Nature preservation. On the other hand, a lot of territories are raised to different level of protection. The authors enumerate the consequences of the new act and European directives on the practice of the entomology in Wallonia. [less ▲]

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See detailRespiratory responses of mature horses to intravenous lobeline bolus
Marlin, D. J.; Roberts, C. A.; Schroter, R. C. et al

in Equine Veterinary Journal (2000), 32(3), 200-207

The respiratory stimulant lobeline has been used in equine clinical practice to increase inspiratory and expiratory airflow rates at rest in orderto facilitate investigation of both lower and upper airway ... [more ▼]

The respiratory stimulant lobeline has been used in equine clinical practice to increase inspiratory and expiratory airflow rates at rest in orderto facilitate investigation of both lower and upper airway function. Some of the responses to lobeline in the pony have been reported, but the detailed time course, effect of dose, possible side effects and reproducibility associated with lobeline administration have not been described in the horse. Respiratory airflow rates and oesophageal pre s s u re were measured with a Fleisch No. 5 pneumotachometer and lightweight facemask and amicrotip pressure transducer catheter, respectively. The output of the Fleisch pneumotachometer was calibrated for flow rates up to ± 70 l/s. Seven mature horses with no clinical signs of respiratory disease were studied. Investigations were conducted to determine: (1) the responses to different doses of lobeline (0.15, 0.20, 0.25 and 0.30 mg/kg bwt) as a rapid i.v. bolus (6 horses); (2) arterial blood gases during and after lobeline administration (0.20 mg/kg bwt; 3 horses); and (3) the reproducibility of lobeline-stimulated hyperpnoea (5 horses; 2 doses of 0.20 mg/kg bwt lobeline, 15 min apart). All horses tolerated the lobeline-stimulated hyperpnoea well, although one always coughed or snorted at the onset. Mild tremor was noted following the highest dose in several horses. Apnoea of approximately 40 s was common after the hyperpnoea. Both tidal volume (VT) and frequency (fR) increased with lobeline dose. During peak hyperpnoea at a dose of 0.30 mg/kg bwt, peak inspired flow rate (PIF), peak expired flow rate (PEF) and minute ventilation (.VE) were mean ± s.e. 41 ± 5 l/s, 61 ± 10 l/s and 920 ± 99 l/min, respectively. The hyperpnoea also caused marked changes in arterial PaO2, PaCO2 and pHa at 90 s after lobeline (0.20 mg/kg bwt) administration (mean ± s.e. 146.0 ± 6.9 mmHg, 20.6 ± 0.8 mmHg and 7.707 ± 0.020, respectively) compared to at rest (mean ± s.e. 104.0 ± 4.0 mmHg, 50.6 ± 2.8 mmHg and 7.432 ± 0.012). Dynamic lung compliance (Cdyn) was unaltered by lobeline administration. The lobeline-induced hyperpnoea was highly reproducible, with no significant difference in any of the parameters during 2 stimulations 15 min apart. Lobeline induced highly reproducible responses without any apparent adverse effects and may be useful in the investigation of pulmonary function in healthy horses and those with airway disease. [less ▲]

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See detailDoppler ultrasonography and single-fiber laser Doppler flowmetry for measurement of hind limb blood flow in anesthetized horses
Raisis, Anthea L; Young, Lesley E; Taylor, Polly M et al

in American Journal of Veterinary Research (2000), 61(3), 286-290

OBJECTIVE: To use Doppler ultrasonography and single-fiber laser Doppler flowmetry (LDF) to evaluate blood flow in the dependent and nondependent hind limbs of anesthetized horses and to evaluate changes ... [more ▼]

OBJECTIVE: To use Doppler ultrasonography and single-fiber laser Doppler flowmetry (LDF) to evaluate blood flow in the dependent and nondependent hind limbs of anesthetized horses and to evaluate changes in femoral arterial blood flow and microvascular skeletal muscle perfusion in response to administration of phenylephrine hydrochloride or dobutamine hydrochloride. ANIMALS: 6 healthy adult horses. PROCEDURE: Horses were anesthetized and positioned in left lateral recumbency. Doppler ultrasonography was used to measure velocity and volumetric flow in the femoral vessels. Single-fiber LDF was used to measure relative microvascular perfusion at a single site in the semimembranosus muscles. Phenylephrine or dobutamine was then administered to decrease or increase femoral arterial blood flow, and changes in blood flow and microvascular perfusion were recorded. RESULTS: Administration of phenylephrine resulted in significant decreases in femoral arterial and venous blood flows and cardiac output and significant increases in mean aortic blood pressure, systemic vascular resistance, and PCV. Administration of dobutamine resulted in significant increases in femoral arterial blood flow, mean aortic blood pressure, and PCV. Significant changes in microvascular perfusion were not detected. CONCLUSION AND CLINICAL RELEVANCE: Results suggest that Doppler ultrasonography and single-fiber LDF can be used to study blood flows in the hind limbs of anesthetized horses. However, further studies are required to determine why changes in femoral arterial blood flows were not associated with changes in microvascular perfusion [less ▲]

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See detailKinetic and spectroscopic characterization of native and metal-substituted beta-lactamase from Aeromonas hydrophila AE036.
Hernandez Valladares, M.; Kiefer, M.; Heinz, U. et al

in FEBS letters (2000), 467(2-3), 221-5

Two metal ion binding sites are conserved in metallo-beta-lactamase from Aeromonas hydrophila. The ligands of a first zinc ion bound with picomolar dissociation constant were identified by EXAFS ... [more ▼]

Two metal ion binding sites are conserved in metallo-beta-lactamase from Aeromonas hydrophila. The ligands of a first zinc ion bound with picomolar dissociation constant were identified by EXAFS spectroscopy as one Cys, two His and one additional N/O donor. Sulfur-to-metal charge transfer bands are observed for all mono- and di-metal species substituted with Cu(II) or Co(II) due to ligation of the single conserved cysteine residue. Binding of a second metal ion results in non-competitive inhibition which might be explained by an alternative kinetic mechanism. A possible partition of metal ions between the two binding sites is discussed. [less ▲]

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See detailOppositions locales et dynamiques d'environnementalisation
Mormont, Marc ULg; Bertrand, Anne

in Espaces et Sociétés (Paris, France) (2000), (101-102), 93-112

Local conflicts provoke collective action that through new coalitions induce reformulations of the problems and elarge scope and scaling of environmental problems. These processes are called ecologization ... [more ▼]

Local conflicts provoke collective action that through new coalitions induce reformulations of the problems and elarge scope and scaling of environmental problems. These processes are called ecologization dynamics and are going to transform environmental politics. [less ▲]

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See detailLes propriétés de la glucosamine
Reginster, Jean-Yves ULg; Halkin, V

in Journal de Pharmacie de Belgique (2000), 55(5), 118-121

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See detailL'écriture en chantier. Une brochure destinée aux enseignants du secondaire
Baye, Ariane ULg; Denooz, Régine

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), 7-8

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See detailA potent diazoxide analogue activating ATP-sensitive K+ channels and inhibiting insulin release
Lebrun, P.; Arkhammar, P.; Antoine, M.-H. et al

in Diabetologia (2000), 43

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See detailMass Transfer Across an Interface Induces Formation of Droplets in Lattice Systems
Pfennig, Andreas ULg

in Chemical Engineering Science (2000), 55(22), 5333-5339

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See detailSimulation of first and second order scattering by rough surfaces with a sound ray formalism
Embrechts, Jean-Jacques ULg

in Journal of Sound & Vibration (2000), 229(1)

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See detailPhysostigmine reverses propofol-induced unconsciousness and attenuation of the auditory steady state response and bispectral index in human volunteers.
Meuret, Pascal; Backman, Steven; Bonhomme, Vincent ULg et al

in Anesthesiology (2000), 93(3), 708-17

BACKGROUND: It is postulated that alteration of central cholinergic transmission plays an important role in the mechanism by which anesthetics produce unconsciousness. The authors investigated the effect ... [more ▼]

BACKGROUND: It is postulated that alteration of central cholinergic transmission plays an important role in the mechanism by which anesthetics produce unconsciousness. The authors investigated the effect of altering central cholinergic transmission, by physostigmine and scopolamine, on unconsciousness produced by propofol. METHODS: Propofol was administered to American Society of Anesthesiologists physical status 1 (n = 17) volunteers with use of a computer-controlled infusion pump at increasing concentrations until unconsciousness resulted (inability to respond to verbal commands, abolition of spontaneous movement). Central nervous system function was assessed by use of the Auditory Steady State Response (ASSR) and Bispectral Index (BIS) analysis of electrooculogram. During continuous administration of propofol, reversal of unconsciousness produced by physostigmine (28 microgram/kg) and block of this reversal by scopolamine (8.6 microgram/kg) were evaluated. RESULTS: Propofol produced unconsciousness at a plasma concentration of 3.2 +/- 0.8 (+/- SD) microgram/ml (n = 17). Unconsciousness was associated with reductions in ASSR (0.10 +/- 0.08 microV [awake baseline 0.32 +/- 0.18 microV], P < 0.001) and BIS (55.7 +/- 8.8 [awake baseline 92.4 +/- 3.9], P < 0.001). Physostigmine restored consciousness in 9 of 11 subjects, with concomitant increases in ASSR (0.38 +/- 0.17 microV, P < 0.01) and BIS (75.3 +/- 8.3, P < 0.001). In all subjects (n = 6) scopolamine blocked the physostigmine-induced reversal of unconsciousness and the increase of the ASSR and BIS (ASSR and BIS during propofol-induced unconsciousness: 0.09 +/- 0.09 microV and 58.2 +/- 7.5, respectively; ASSR and BIS after physostigmine administration: 0.08 +/- 0.06 microV and 56.8 +/- 6.7, respectively, NS). CONCLUSIONS: These findings suggest that the unconsciousness produced by propofol is mediated at least in part via interruption of central cholinergic muscarinic transmission. [less ▲]

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See detailRevue bibliographique : l’hydroperoxyde lyase
Delcarte, Jérome; Fauconnier, Marie-Laure ULg; Hoyaux, Phryné et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(3), 157-167

The hydroperoxide lyase belongs to the lipoxygenase pathway, pathway in which polyunsaturated fatty acids are transformed into a large spectrum of compounds with various chemical and biological functions ... [more ▼]

The hydroperoxide lyase belongs to the lipoxygenase pathway, pathway in which polyunsaturated fatty acids are transformed into a large spectrum of compounds with various chemical and biological functions. The hydroperoxide lyase acts on fatty acids hydroperoxides (mainly linoleic and linolenic). It cleaves the bond between carbon carrying the hydroperoxide function and a vicinal carbon giving an w-oxo-acid and also depending on the species, an aldehyde, a hydrocarbon or an alcohol. [less ▲]

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See detailA homologous radioimmunoassay for quantification of insulin-like growth factor-binding protein-2 in blood from cattle.
Vleurick, Lieve; Renaville, Robert ULg; VandeHaar, M. et al

in Journal of Dairy Science (2000), 83(3), 452-8

Insulin-like growth factor-I and -II (IGF-I, IGF-II) circulate in biological fluids bound to six different IGF-binding proteins that regulate IGF bioactivity. The IGF-binding protein-2 is regulated by ... [more ▼]

Insulin-like growth factor-I and -II (IGF-I, IGF-II) circulate in biological fluids bound to six different IGF-binding proteins that regulate IGF bioactivity. The IGF-binding protein-2 is regulated by growth hormones, and its concentration depends on nutrition and physiological state. Specific antibodies directed against bovine IGF-binding protein-2 were produced, and IGF-binding protein-2 levels in bovine blood samples were quantified by radioimmunoassay. Parallel displacement curves showed strong cross-reactivity with bovine and ovine plasma, were low with porcine plasma, and no cross-reactivity with rat or chicken plasma. Addition of IGF-I or -II to a control pool of bovine plasma did not significantly alter control IGF-binding protein-2 values in a radioimmunoassay. Six nycthemeral periods, determined for three young bulls bled on two occasions, showed that IGF-binding protein-2 plasma levels were stable throughout the day; two or three samples were sufficient to characterize the animal. Cows treated with recombinant bovine somatotropin (bST) had significantly lower serum levels of IGF-binding protein-2 than did control cows. Furthermore, IGF-binding protein-2 levels were dramatically increased at the onset of lactation. This radioimmunoassay for bovine IGF-binding protein-2, which enables quantitative assessment of IGF-binding protein-2 concentration in cattle, confirmed that IGF-binding protein-2 concentrations are depressed by administration of bST, enhanced after calving, and showed absence of diurnal variation. [less ▲]

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See detail“Cross-Cultural Dialogues with Greek Classics: Walcott’s The Odyssey and Soyinka’s The Bacchae of Euripides.”
Bada, Valérie ULg

in Ariel : A Review of International English Literature (2000)

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See detailLa douleur pelvienne chez le patient oncologique
Jansen, Nicolas ULg; Nickers, Philippe ULg; Devoghel, Jean-Claude ULg

in Oncologie (2000), 2(4), 187-200

Pelvic pain is a common problem in the general population. In cancer patients this pain can be secondary to tumor activity or recent tumor related interventions (surgery, radiotherapy, chemotherapy). On ... [more ▼]

Pelvic pain is a common problem in the general population. In cancer patients this pain can be secondary to tumor activity or recent tumor related interventions (surgery, radiotherapy, chemotherapy). On the other hand cancer patients can also suffer from not cancer related pain. Cancer related pain is often chronic. Whatever the cause of this pain, an important psychological factor is often present, if not attributing to the pathogenesis of the pain, then as an secondary effect from the pain. Managing pelvic pain requires knowledge of the regional anatomy. A general overview is given of the approach to an oncological patient presenting with pelvic pain. Three different possibilities are discussed: (1) pain in a patient without a presently known pelvic or abdominal malignancy, (2) pain in a patient treated recently for a tumor in the pelvic area or lower abdomen, (3) pain in an so far untreated patient with a known tumor. Finally an overview of treatment options is presented. [less ▲]

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See detailThe medical management of severe acute and chronic ulcerative colitis--current recommendations from the Belgian Working Group.
Melange, M.; D'Haens, G.; Devos, Martine ULg et al

in Acta Gastro-Enterologica Belgica (2000), 63(3), 273-4

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See detailTherapeutic and chemical developments of cholecystokinin receptor ligands
De Tullio, Pascal ULg; Delarge, J.; Pirotte, Bernard ULg

in Exp. Opin. Invest. Drugs (2000), 9

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See detailAutour de Stavelot-Malmedy (VIIe-IXe siècles)
George, Philippe ULg

in Publications de la Section Historique de l'Institut Royal Grand-Ducal de Luxembourg (2000)

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See detailViroses tropicales éruptives
Fraiture, A. L.; Nikkels, Arjen ULg; Pierard-Franchimont, Claudine ULg et al

in Revue Médicale de Liège (2000), 55

Eruptive tropical viroses are severe diseases which may prove to be sometimes fatal diseases. They are characterized by erythémato-purpuric cutaneous lesions associated with hyperthermia. Polyarthralgia ... [more ▼]

Eruptive tropical viroses are severe diseases which may prove to be sometimes fatal diseases. They are characterized by erythémato-purpuric cutaneous lesions associated with hyperthermia. Polyarthralgia or severe haemorrhage can also be part of the clinical presentation. Rapid diagnosis and preventive measures are mandatory, particularly when human transmission is possible. [less ▲]

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See detailEffects of glucocorticoids on hepatic sensitivity to insulin and glucagon in man.
Dirlewanger, M.; Schneiter, P. H.; Paquot, Nicolas ULg et al

in Clinical Nutrition (2000), 19(1), 29-34

AIMS: This study was undertaken to determine the effects of a short-term dexamethasone treatment on hepatic sensitivities to insulin and glucagon. METHODS: Eleven healthy subjects were studied during one ... [more ▼]

AIMS: This study was undertaken to determine the effects of a short-term dexamethasone treatment on hepatic sensitivities to insulin and glucagon. METHODS: Eleven healthy subjects were studied during one or several of four protocols. In all protocols, somatostatin was infused continuously to inhibit pancreatic hormone secretion. In protocol 1, basal insulin was infused over 300 min while glucagon was infused at a rate of 0.5 mg/kg(-1)/min(-1)during 180 min, then at a rate of 1.5 ng/kg(-1)/min(-1)during 150 min. In protocol 2, the same experiment was performed after a 2 day treatment with 8 mg/day dexamethasone. In protocol 3, the two-step glucagon infusion was performed during insulin infusion at a rate aimed to reproduce the hyperinsulinemia observed during protocol 2. In protocol 4, continuous basal insulin and low glucagon (0.5 mg/kg(-1)/min(-1)) were infused over 330 min. RESULTS: In protocol 1, plasma glucose rose transiently by 2.0 +/- 0.3 mmol/l when the glucagon rate was increased and glucose production increased by 1.4 +/- 0.5 micromol/kg(-1)/min(-1). In protocol 2, the insulin infusion rate (1.85 +/- 0.36 nmol/kg(-1)/min(-1)) required to maintain glycemia was 3.3-fold higher than during protocol 1. Glucagon-induced stimulation of glycemia (by 1.47 +/- 0.5 mmol/l) and endogenous glucose production (by 0.8 +/- 0.3 micromol/kg(-1)/min(-1)) were blunted, but not abolished. In protocol 3, endogenous glucose production was suppressed by 75% by hyperinsulinemia and was not stimulated when the glucagon infusion rate was increased. In protocol 4, endogenous glucose production did not change significantly with time. CONCLUSION: These results indicate that high dose glucocorticoids induce a marked hepatic insulin resistance. Stimulation of glucose production by hyperglucagonemia was maintained in spite of hyperinsulinemia which can be attributed to either hepatic insulin resistance and/or increased hepatic glucagon sensitivity. [less ▲]

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See detailEnantioselective Syntheses and Absolute Configuration of the Ladybird Defence Alkaloids (+)-Calvine and (+)-2-Epicalvine
Laurent, Pascal ULg; Braekman, Jean-Claude; Daloze, Désiré

in European Journal of Organic Chemistry (2000), 11

Enantiomerically pure (+)-calvine (1a) and (+)-2-epicalvine (Ib), two piperidine alkaloids isolated from ladybird beetles of the genus Calvia (Coccinellidae), were synthesized by two different strategies ... [more ▼]

Enantiomerically pure (+)-calvine (1a) and (+)-2-epicalvine (Ib), two piperidine alkaloids isolated from ladybird beetles of the genus Calvia (Coccinellidae), were synthesized by two different strategies starting from (-)-2,3,6,7,8,8a-hexahydro-3-phenyl-5H-[1,3]oxazolo[3,2-a]pyridine-5-carbonitrile (2). The key steps of these syntheses are the stereocontrolled formation of an asymmetric centre a to the nitrogen atom of 2 and the subsequent introduction of the methoxycarbonylmethyl substituent at the u'-position. Comparison of the optical rotations of the synthetic benzoates (12a) and (12b) with those of the corresponding benzoates derived from the natural compounds has revealed the absolute configuration of (+)-calvine to be (2S,6S) and that of (+)-2-epicalvine to be (2R,6S). [less ▲]

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See detailRural Labor Flows in China
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2000), Vol. XVIII

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See detailOuverture
Maes-Jelinek, Hena ULg

in Journal of Caribbean Literatures (2000), 2(1/2/3), 6-16

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See detailA simple method for neutrophils isolaton in horse
Votion, Dominique ULg; Harmegnies, N. F.; Lekeux, Pierre ULg

in European Journal of Nuclear Medicine (2000), 27

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See detailChanging dynamics of the Loire river in Burgundy (France) during the last 200 years
Leteinturier, B.; Engels, Patrick ULg; Petit, François ULg et al

in Géomorphologie : Relief, Processus, Environnement (2000)

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See detailVitamines anti-oxydantes dans la prevention des maladies cardio-vasculaires. 1ere partie: Le point sur les etudes epidemiologiques.
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(1), 11-8

The hypothesis of the atherogenic role of oxidized. LDL lipoproteins and the observation of the longevity of individuals on a "mediterranean diet" led to the concept that antioxidant vitamins may exert ... [more ▼]

The hypothesis of the atherogenic role of oxidized. LDL lipoproteins and the observation of the longevity of individuals on a "mediterranean diet" led to the concept that antioxidant vitamins may exert cardiovascular protective effects. In this first article, we summarize the results of the main epidemiological studies which analyzed the influence of dietary intakes (or resulting plasma concentrations) in vitamin E (alpha-tocopherol), vitamin A (beta-carotene) or vitamin C (ascorbic acid). The three types of studies available in the literature provided quite heterogeneous results, in favour of a protective role of antioxidant vitamins as far as cross-cultural and most prospective observational studies were concerned, but rather negative when considering case-control studies. However, in general, epidemiological studies tended to support, a beneficial role of these antioxidant vitamins to prevent cardiovascular diseases, at least in some subgroups of individuals. [less ▲]

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See detailHuitième campagne de fouilles à Tell Beydar
Van der Stede, Véronique ULg; Talon, Philippe

in Annales d'Histoire de l'Art et d'Archéologie (2000), XXII

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See detailCoupled thermo-magnetic simulation of a foil-winding transformer connected to a non-linear load
Driesen, Johan; Deliège, Geoffrey ULg; Belmans, Ronnie et al

in IEEE Transactions on Magnetics (2000), 36(4), 1381-1385

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See detailComment j'explore ... les anomalies du metabolisme glucidique, de l'insulinosecretion et de la sensibilite a l'insuline avec une hyperglycemie provoquee par voie orale.
Luyckx, Françoise ULg; Scheen, André ULg

in Revue Médicale de Liège (2000), 55(9), 881-5

Oral glucose tolerance test (OGTT) has been widely used for the diagnosis of diabetes mellitus, gestational diabetes, impaired glucose tolerance or reactive hypoglycaemia. Simultaneous measurements of ... [more ▼]

Oral glucose tolerance test (OGTT) has been widely used for the diagnosis of diabetes mellitus, gestational diabetes, impaired glucose tolerance or reactive hypoglycaemia. Simultaneous measurements of plasma glucose and insulin levels also allow to derive indices of insulin secretion and insulin sensitivity. Whereas OGTT is not considered anymore as the first choice for the diagnosis of diabetes mellitus, it remains useful for studying abnormalities of glucose metabolism as well as of insulin secretion and insulin action. [less ▲]

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See detailElectrophysiological behavior of Purkinje cells and motor coordination in calretinin knock-out mice
Cheron, Guy; Schurmans, Stéphane ULg; Lohof, Ann et al

in Progress in Brain Research (2000), 124

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See detailClinical impact and perspectives of 18F-FDG PET in lymphoma
Jerusalem, Guy ULg; Beguin, Yves ULg

in Clinical Lymphoma (2000), 1

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See detailA survey on staging and treatment in uterine cervical carcinoma in the Radiotherapy Cooperative Group of the European Organization for Research and Treatment of Cancer
Coucke, Philippe ULg; Maingon, P; Ciernik, I et al

in Radiotherapy & Oncology (2000), 54

Abstract Background: The treatment outcome of advanced stage uterine cervical carcinoma remains unsatisfactory. In order to elaborate a novel trial within The Radiotherapy Cooperative Group (RCG) of the ... [more ▼]

Abstract Background: The treatment outcome of advanced stage uterine cervical carcinoma remains unsatisfactory. In order to elaborate a novel trial within The Radiotherapy Cooperative Group (RCG) of the European Organization for Research and Treatment of Cancer (EORTC), we conducted a survey in 1997±1998 to determine the variability of pre-treatment assessment and treatment options. The variability of choosing surgery, de®ned radiation therapy techniques and chemotherapy are investigated, as well as the center's choices of future treatment strategies. Methods: Fifty two of 81 RCG centers from the RCG have participated in the survey. As one would expect, there is a large variation in the techniques used for pretreatment evaluation and treatment options. There is no `standard' for reporting acute and late side effects. Chemotherapy is used neither systematically nor uniformly, and some centers continue to use neadjuvant chemotherapy modalities. Results: Furthermore, the survey reveals that there is a strong demand for the reduction of overall treatment-time, for clinical investigation of novel combined modality treatment strategies, especially chemo±radiation therapy, and also for the use of new radiation sensitizers. Conclusion:We conclude that a more homogeneous approach to the pretreatment evaluation as well as treatment techniques is required in order to allow adequate quality control in any future trial of the RCG in the EORTC.q2000 Elsevier Science Ireland Ltd. All rights reserved. [less ▲]

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See detailPharma-clinics. Le medicament du mois. La moxonidine (Moxon).
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(1), 61-3

Moxonidine (Moxon, Solvay Pharma) is the first member of a new class of centrally-acting antihypertensive agents. The selective activation of central I1 imidazoline receptors results in an inhibition of ... [more ▼]

Moxonidine (Moxon, Solvay Pharma) is the first member of a new class of centrally-acting antihypertensive agents. The selective activation of central I1 imidazoline receptors results in an inhibition of peripheral sympathetic activity and produces arterial vasodilatation. Moxonidine is indicated in the treatment of essential arterial hypertension, at a usual daily dose of 0.4 mg (initial dose of 0.2 mg/day), in one administration per day. Its tolerance profile is better than that of other centrally-acting antihypertensive agents which stimulate alpha-2 adrenergic receptors, and similar to that of medications of other classes. As monotherapy, the antihypertensive efficacy of moxonidine is similar to that of most other antihypertensive agents. In case of insufficient response, moxonidine may be associated with other antihypertensive compounds, which leads to a better efficacy with no deterioration of its good tolerance profile. [less ▲]

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See detailDexamethasone Ester Treatment Alters Insulin-Like Growth Factor-I, Its Binding Proteins And Thyroid Status In Finishing Calves
Bertozzi, C.; Portetelle, Daniel ULg; Massart, Serge et al

in Canadian Journal of Animal Science (2000), 80(2),

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See detailComparaison des treillis classiques de type Warren, Pratt et Howe : optimisation et prédimensionnement sur base d'indicateurs morphologiques
Latteur, Pierre ULg; Samyn, Philippe; De Wilde, Patrick

in Revue Française de Génie Civil (2000), 4

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See detailLa carte des émotions : exercice structuré
Faulx, Daniel ULg

in Cahiers Internationaux de Psychologie Sociale (2000), (45), 98-103

Cet outil permet d'identifier et d'analyser la présence, la circulation et la gestion des émotions au sein d'une équipe de travail ou d'un groupe. Il propose différents modes de mesure de l'émotion au ... [more ▼]

Cet outil permet d'identifier et d'analyser la présence, la circulation et la gestion des émotions au sein d'une équipe de travail ou d'un groupe. Il propose différents modes de mesure de l'émotion au sein des groupes, et constitue à ce titre à la fois un outil de mesure et d'intervention ou de développement. [less ▲]

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See detailSynthesis and biological effects of new 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides on insulin-secreting cells
Somers, F.; De Tullio, Pascal ULg; Boverie, S. et al

in Pharmacy and Pharmacology Communications (2000), 6

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See detailLa grippe: de la prevention vaccinale au traitement antiviral.
Nkoghe, D.; Scheen, André ULg

in Revue Médicale de Liège (2000), 55(1), 19-23

Influenza is a highly infectious disease responsible for dangerous epidemics, especially in patients at high risk. The vaccine exerts a valuable protective effect estimated up to 70% and is still ... [more ▼]

Influenza is a highly infectious disease responsible for dangerous epidemics, especially in patients at high risk. The vaccine exerts a valuable protective effect estimated up to 70% and is still considered as the key-approach against influenza. Antiviral agents of the first generation (amantadine, rimantadine, ribavirine) have limited use because of poor tolerance and occurrence of resistance. Zanamivir or Relenza, marketed by Glaxo Wellcome, is a new virostatic drug acting as a neuraminidase inhibitor. It prevents the release of new viruses and so stop the propagation of the infection. It must be taken orally by inhalation within 48 hours after the onset of symptoms. The treatment lasts 5 days (10 mg twice daily). Its efficacy has been demonstrated in controlled clinical trials, and its tolerance is generally excellent. However, caution is recommended in patients with asthma and chronic bronchitis because of the potential risk of bronchoconstriction. No resistance has been detected until now. Zanamivir is active on all strains of influenza A and B viruses. [less ▲]

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See detailLa vie quotidienne à Stavelot-Malmedy autour de l'an mil. Moines & société à travers les Miracula Remacli
George, Philippe ULg

in Bulletin de l'Institut historique liégeois (2000)

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See detailÀ la recherche de l'«art public» dans les villes de la Mésopotamie
Tunca, Önhan ULg

in Art&Fact (2000), 19

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See detailRecent advances in inducible cyclooxygenase (COX-2) inhibition
De Leval, X.; Delarge, J.; Somers, F. et al

in Current Medicinal Chemistry (2000), 7(10), 1041-1062

Cyclooxygenase is the key enzyme in the biosynthesis of prostanoids, biologically active substances that are involved in several physiological processes but also in pathological conditions such as ... [more ▼]

Cyclooxygenase is the key enzyme in the biosynthesis of prostanoids, biologically active substances that are involved in several physiological processes but also in pathological conditions such as inflammation. Since ten years now, it is well known that this enzyme exists under two forms: a constitutive (COX-1) and an inducible form (COX-2). Both enzymes are sensitive to inhibition by conventional nonsteroidal anti-inflammatory drugs (NSAIDs). Observations that COX-1, involved in several homeostatic processes, played a housekeeping role while COX-2 expression was associated with inflammation and other pathologies such as cancer proliferation have led to the development of COX-2 selective inhibitors in order to reduce the classical side-effects, of which gastric irritation is the most common, associated with the use of conventional NSAIDs. [less ▲]

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See detailERK activation upon hypoxia: involvement in HIF-1 activation.
Minet, E.; Arnould, T.; Michel, G. et al

in FEBS Letters (2000), 468(1), 53-8

Hypoxia-inducible factor-1 (HIF-1) is a transcription factor activated by hypoxia. The HIF-1 activation transduction pathway is poorly understood. In this report, we investigated the activation of ... [more ▼]

Hypoxia-inducible factor-1 (HIF-1) is a transcription factor activated by hypoxia. The HIF-1 activation transduction pathway is poorly understood. In this report, we investigated the activation of extracellular regulated kinases (ERK) in hypoxia and their involvement in HIF-1 activation. We demonstrated that in human microvascular endothelial cells-1 (HMEC-1), ERK kinases are activated during hypoxia. Using dominant negative mutants, we showed that ERK1 is needed for hypoxia-induced HIF-1 transactivation activity. Moreover, using a kinase assay and Western blot experiments, we showed that HIF-1alpha is phosphorylated in hypoxia by an ERK-dependent pathway. These results evidence the role of mitogen-activated protein kinase in the transcriptional response to hypoxia. [less ▲]

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See detailClinical Usefulness of the Mini Nutritional Assessment (Mna) Scale in Geriatric Medicine
Gazzotti, C.; Albert, Adelin ULg; Pepinster, A. et al

in Journal of Nutrition, Health & Aging (The) (2000), 4(3), 176-81

OBJECTIVE: This study was undertaken to estimate the prevalence of malnutrition in elderly patients hospitalized with an acute illness, as well as to assess the clinical usefulness of standardized ... [more ▼]

OBJECTIVE: This study was undertaken to estimate the prevalence of malnutrition in elderly patients hospitalized with an acute illness, as well as to assess the clinical usefulness of standardized nutritional assessment upon admission by means of the MNA scale. Design: A prospective study. Setting: A large size regional university hospital. Subjects: There were 175 patients (113 women and 62 men) with a mean age of 79.7 + 8.5 years admitted for an acute problem. Death occurred in 11 patients (6.3%). METHODS: Upon admission, demographic (age, gender, origin) and medical (disease, drugs) data were recorded for each patient; the MNA questionnaire (score: 0-30) was administered and Katz score (7-28) calculated. At hospital discharge, data included Katz score, outcome (death/survival), and destination. RESULTS: The mean MNA score was 20.5 + 5.1 and the prevalence of severe malnutrition (MNA <17) was 21.7%. Further, 48.6% of elderly were at risk of malnutrition (MNA between 17 and 24). There was no association between MNA and age or gender, but underweight was a sign of low MNA values (P <.001). MNA scores were inversely related to Katz scores at both admission and hospital discharge (P <.001). Patients originating from nursing homes had a poorer nutritional status than those living at home (MNA: 18.4 against 22.3, P <.001). The number of drugs taken per patient (5.2 + 2.8) was found to be correlated with MNA (P =.049). MNA scores were on average significantly higher (P <.001) in survivors (20.9) than in nonsurvivors (14.1). CONCLUSIONS: The study clearly demonstrates the high prevalence of malnutrition and the clinical usefulness of the MNA scale in geriatric medicine. The MNA score upon admission reflects the patient's nutritional condition, degree of autonomy (Katz score), living conditions and current treatment. It is also predictive of patient's outcome (death or survival). [less ▲]

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See detailProgress in Arabidopsis genome sequencing and functionnal genomics.
Wambutt, R.; Portetelle, Daniel ULg; Vandenbol, Micheline ULg et al

in Journal of Biotechnology (2000), 78

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See detailEffects of 3-alkylamino-7-chloro-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxides on smooth muscle contractile activity
Ouedraogo, R.; Fontaine, J.; Antoine, M.-H. et al

in Pharmacy and Pharmacology Communications (2000), 6

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See detailL’intégration de l’estompage dans les spatiocartes
Donnay, Jean-Paul ULg

in Bulletin de la Société Géographique de Liège (2000), 38

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See detailA 1H, 13C, 31P and 15N NMR study of (pyrrolidine-2,2-diyl)bisphosphonic acid, tetraalkyl(pyrrolidine-2,2-diyl)bisphosphonates and acyclic tetraethyl bisphosphonates
Olive, Gilles ULg; van Genderen, Marcel H P

in Magnetic Resonance in Chemistry [=MRC] (2000), 38(5), 379-381

A multinuclear magnetic resonance study (1H, 13C, 31P, 15N) was performed on a series of new cyclic pyrrolidine bisphosphonates and acyclic bisphosphonates. Values are reported and discussed for the ... [more ▼]

A multinuclear magnetic resonance study (1H, 13C, 31P, 15N) was performed on a series of new cyclic pyrrolidine bisphosphonates and acyclic bisphosphonates. Values are reported and discussed for the chemical shifts and coupling constants of the various nuclei. [less ▲]

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See detailThe bushlike radiation of muroid rodents is exemplified by the molecular phylogeny of the LCAT nuclear gene.
Michaux, Johan ULg; Catzeflis, F.

in Molecular Phylogenetics & Evolution (2000), 17(2), 280-93

Phylogenetic relationships among 40 extant species of rodents, with an emphasis on the taxonomic sampling of Muridae and Dipodidae, were studied using sequences of the nuclear protein-coding gene LCAT ... [more ▼]

Phylogenetic relationships among 40 extant species of rodents, with an emphasis on the taxonomic sampling of Muridae and Dipodidae, were studied using sequences of the nuclear protein-coding gene LCAT (lecithin cholesterol acyl transferase). Analysis of 804 bp from the exonic regions of LCAT confirmed many traditional groupings in and around Muridae. A strong support was found for the families Muridae (represented by 29 species) and Dipodidae (5 species). Compared with Sciuridae, Gliridae, and Caviomorpha, the Dipodidae family appeared the closest relative of Muridae, confirming the suprafamilial Myodonta concept. Within the speciose family Muridae, the first branching leads to the fossorial Spalacinae and semifossorial Rhyzomyinae. The remaining components of Muridae appear as a polytomy from which are issued Sigmodontinae, Calomyscinae, Arvicolinae, Cricetinae, Mystromyinae, Nesomyinae, and some Dendromurinae (Steatomys and Dendromus). This phylogeny is interpreted as the result of a bushlike radiation at the end of the early Miocene, leading to emergence of most living subfamilies. The separation between three additional taxa, Murinae, Gerbillinae, and "Acomyinae" (which comprises the genera Acomys, Deomys, Uranomys, and Lophuromys), has occurred more recently from a common ancestor issued from the main basal radiation. As previously shown by other molecular studies, the vlei rats, Otomyinae, are nested within Old World Murinae. In the same way, the zokors, Myospalacinae, appear strongly nested within the hamsters, Cricetinae. Finally, we propose a sister group relationship between Malagasy Nesomyinae and south African Mystromyinae. [less ▲]

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See detailHeart Graft Monitoring by the Ventricular Evoked Response
Mahaux, V.; Demoulin, J.C.; BIESSAUX, Yves ULg et al

in Pacing & Clinical Electrophysiology (2000), 23(11, Pt 2), 2003-5

Monitoring of the negative slew rate of the evoked T wave has been proposed as a noninvasive diagnostic tool to follow heart transplant recipients. The clinical contribution of this measurement on ... [more ▼]

Monitoring of the negative slew rate of the evoked T wave has been proposed as a noninvasive diagnostic tool to follow heart transplant recipients. The clinical contribution of this measurement on telemetrically recorded, paced unipolar ventricular electrograms was evaluated in the detection of grade 3 acute allograft rejection. Thirteen patients undergoing heart transplantation received a DDD pacemaker connected to two epimyocardial leads. Electrograms were recorded and digitized after each endomyocardial biopsy (EMB). The maximum slew rate of the descending slope of the repolarization phase (RSP) was extracted and normalized. A 20% downward shift of RSP from the reference value was considered abnormal. Results of signal processing were blinded during the first 6 months. Eleven patients completed the 6 months blinded period and two patients died. A total of 101 EMB were graded according to the International Society for Heart and Lung Transplantation classification. Grade 3 was assigned to 9 EMB. A significant difference was found between RSP values measured during grade 3 rejection episodes and other RSP values (P < 0.001). A diagnostic model consisting of a single threshold test confirmed the ability of RSP to predict significant signs of rejection on EMB (P < 0.0001). The sensitivity of RSP in detecting grade 3 rejections was 100%, specificity was 81%, negative predictive value 100%, and positive predictive value 35%. The use of RSP as a noninvasive monitoring tool to pose the indication for a biopsy would avoid 73% of EMB. Monitoring of transplanted hearts based on the analysis of the ventricular evoked response is promising and may markedly reduce the number of EMB. [less ▲]

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See detailAdenovirus infections in pigeons
Duchatel, Jean-Pierre ULg; Marlier, Didier ULg; Jauniaux, Thierry ULg et al

in Annales de Médecine Vétérinaire (2000), 144(1), 13-17

This paper describes the different clinical aspects of the adenovirus infections in pigeons. Etiology, epidemiology, pathogenesis, diagnosis and treatment are discussed. The two specific clinical ... [more ▼]

This paper describes the different clinical aspects of the adenovirus infections in pigeons. Etiology, epidemiology, pathogenesis, diagnosis and treatment are discussed. The two specific clinical syndromes of pigeons are mainly described: classical adenovirus and necrotizing-hepatitis. [less ▲]

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See detailKantvilasia (Lecanorales, Ectolechiaceae), a new foliicolous lichen genus from Tasmania
McCarthy, P.M.; Elix, J.A.; Sérusiaux, Emmanuël ULg

in Lichenologist (2000), 32

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See detailVery Low Surfactant Protein C Contents in Newborn Belgian White and Blue Calves with Respiratory Distress Syndrome
Danlois, F.; Zaltash, S.; Johansson, J. et al

in Biochemical Journal (2000), 351(Pt 3), 779-87

We have studied a respiratory distress syndrome (RDS) occurring in newborn calves of the Belgian White and Blue (BWB) breed that represents the large majority of beef cattle in Belgium. Pulmonary ... [more ▼]

We have studied a respiratory distress syndrome (RDS) occurring in newborn calves of the Belgian White and Blue (BWB) breed that represents the large majority of beef cattle in Belgium. Pulmonary surfactant isolated from 14 BWB newborn calves that died from RDS and from 7 healthy controls was analysed for composition and surface activity. An extremely low content or, in some instances, an absence of surfactant protein C (SP-C) was detected in the RDS samples by Western blotting and differential amino acid analysis [0.03+/-0.01% (w/w) relative to total phospholipids, compared with 0.39+/-0.06% for healthy controls (means+/-S.E.M., P < 0.001)]. The contents of surfactant protein B (SP-B) were similar in RDS and control samples. The crude surfactant samples isolated from RDS calves had higher ratios of total protein to total phospholipid, altered phospholipid profiles and lower SP-A contents. Both crude and organic extracts of RDS surfactant samples showed increased dynamic surface tension compared with healthy controls when evaluated with a pulsating-bubble surfactometer. The addition of purified SP-C to organic extracts of RDS surfactant samples lowered surface tension. Strongly decreased levels of mature SP-C associated with fatal RDS and altered surface activity in vitro have, to the best of our knowledge, not been previously reported. The mechanisms underlying RDS and the decrease in SP-C in BWB calves remain to be established. [less ▲]

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See detailEnvironmentally based maternal effect on reproduction of Adalia bipunctata : impact of aphid prey species.
Francis, Frédéric ULg; Defrance, Thibault; Haubruge, Eric ULg et al

in Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen (Rijksuniversiteit te Gent) (2000), 65(2), 303-310

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See detail"note sous J.P. Jumet, 24 février 2000"
Moreau, Pierre ULg

in Actualités du Droit (2000)

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See detailRandomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group.
REGINSTER, Jean-Yves ULg; Minne, H. W.; Sorensen, O. H. et al

in Osteoporosis International (2000), 11(1), 83-91

The purpose of this randomized, double-masked, placebo-controlled study was to determine the efficacy and safety of risedronate in the prevention of vertebral fractures in postmenopausal women with ... [more ▼]

The purpose of this randomized, double-masked, placebo-controlled study was to determine the efficacy and safety of risedronate in the prevention of vertebral fractures in postmenopausal women with established osteoporosis. The study was conducted at 80 study centers in Europe and Australia. Postmenopausal women (n = 1226) with two or more prevalent vertebral fractures received risedronate 2.5 or 5 mg/day or placebo; all subjects also received elemental calcium 1000 mg/day, and up to 500 IU/day vitamin D if baseline levels were low. The study duration was 3 years; however, the 2.5 mg group was discontinued by protocol amendment after 2 years. Lateral spinal radiographs were taken annually for assessment of vertebral fractures, and bone mineral density was measured by dual-energy X-ray absorptiometry at 6-month intervals. Risedronate 5 mg reduced the risk of new vertebral fractures by 49% over 3 years compared with control (p<0.001). A significant reduction of 61% was seen within the first year (p = 0.001). The fracture reduction with risedronate 2.5 mg was similar to that in the 5 mg group over 2 years. The risk of nonvertebral fractures was reduced by 33% compared with control over 3 years (p = 0.06). Risedronate significantly increased bone mineral density at the spine and hip within 6 months. The adverse-event profile of risedronate, including gastrointestinal adverse events, was similar to that of control. Risedronate 5 mg provides effective and well-tolerated therapy for severe postmenopausal osteoporosis, reducing the incidence of vertebral fractures and improving bone density in women with established disease. [less ▲]

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See detailLa prescription de l'action publique
Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2000)

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See detailRelationships between cognitive performance and cerebral metabolism in Alzheimer's disease
Collette, Fabienne ULg; Van der Linden, Martial ULg; Salmon, Eric ULg

in Current Psycholology Letters: Brain, Behavior and Cognition (2000), 1(1), 55-69

The presence of correlations between cerebral metabolism and performance on cognitive tasks (digit span, verbal fluency, Hayling inhibition task and the Mattis dementia rating scale) was assessed in AD ... [more ▼]

The presence of correlations between cerebral metabolism and performance on cognitive tasks (digit span, verbal fluency, Hayling inhibition task and the Mattis dementia rating scale) was assessed in AD patients and elderly controls. Results showed that in both groups the cerebral areas where metabolism was correlated to performance were similar to those found in functional activation studies with young healthy subjects. The comparison of cognitivo-metabolic correlations in AD patients and control subjects showed that the single significant difference was a correlation between posterior cingulate metabolism and performance on the Mattis dementia rating scale in AD patients only. These results are consistent with two neurobiological causes of cognitive impairment in AD : a less efficient functioning of some areas involved in specific cognitive tasks and a deficit of integration of information coming from different areas. [less ▲]

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See detailMechanisms of reduced and compensatory growth.
Hornick, Jean-Luc ULg; Van Eenaeme, Christian ULg; Gerard, O. et al

in Domestic Animal Endocrinology (2000), 19(2), 121-32

Growth is an integrated process, resulting from the response of cells dependent on the endocrine status and nutrient availability. During feed restriction, the production and secretion of growth hormone ... [more ▼]

Growth is an integrated process, resulting from the response of cells dependent on the endocrine status and nutrient availability. During feed restriction, the production and secretion of growth hormone (GH) by the pituitary gland are enhanced, but the number of GH receptors decreases. Changes of GH binding proteins induce GH resistance and are followed by reduced insulin-like growth factor-I (IGF-I) secretion. On the other hand, high circulating levels of GH enhance the mobilization of fatty acids, which are used to support energy requirements. Thus, when feed restriction in growing animals is moderate, there is mainly protein but barely fat accretion. By contrast, a severe feed restriction enhances the release of catabolic hormones and stimulates, from muscle cells, the liberation of amino acids, which are used by hepatocytes for gluconeogenesis. During refeeding and compensatory growth, the secretion of insulin is sharply enhanced and plasma GH concentrations remain high. This situation probably allows more nutrients to be used for growth processes. The role of plasma IGF-I during compensatory growth is not clear and must be explained in connection with changes of its binding proteins. Thyroxin and 3,5,3'-triiodothyronine seem to have a permissive effect on growth. The simultaneous occurrence of puberty with refeeding can exert a synergistic effect on growth. Initially, compensatory growth is characterized by the deposition of very lean tissue, similar as during feed restriction. This lasts for some weeks. Then, protein synthesis decreases and high feed intake leads to increased fat deposition. [less ▲]

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See detailAlteration of thyroid hormones, insulin-like growth factor-I (IGF-I) and IGFBPs in finishing calves treated with dexamethasone
Bertozzi, Carlo; Massart, Serge; Darras, Veerle et al

in Canadian Journal of Animal Science (2000), 80

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See detailChronique de la 54ème Session de la SIHDA à Antalya (24-29 Septembre 2000)
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité (2000), L

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See detailExpression And Activity Of Antioxidant Enzymes During Potato Tuber Dormancy
Rojas-Beltran, Ja.; Dejaeghere, F.; Kotb, Ma. et al

in Potato Research (2000), 43(4),

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See detailCaractéristiques spermatiques des taureaux de race Borgou au Bénin
Adamou N'Diaye, M.; Gbangboche, A.B.; Adjovi, A. et al

in Annales des Sciences Agronomiques du Bénin (2000), 2

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See detailPrincipal component analysis based on robust estimators of the covariance or correlation matrix: Influence functions and efficiencies
Croux, C.; Haesbroeck, Gentiane ULg

in Biometrika (2000), 87(3), 603-618

A robust principal component analysis can be easily performed by computing the eigenvalues and eigenvectors of a robust estimator of the covariance or correlation matrix. In this paper we derive the ... [more ▼]

A robust principal component analysis can be easily performed by computing the eigenvalues and eigenvectors of a robust estimator of the covariance or correlation matrix. In this paper we derive the influence functions and the corresponding asymptotic variances for these robust estimators of eigenvalues and eigenvectors. The behaviour of several of these estimators is investigated by a simulation study. It turns out that the theoretical results and simulations favour the use of S-estimators, since they combine a high efficiency with appealing robustness properties. [less ▲]

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See detailCompte-rendu de Sandra Laugier, Recommencer la philosophie. La philosophie américaine aujourd'hui
Leclercq, Bruno ULg

in Recherches Husserliennes (2000), 13

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See detailAffections musculaires et intolrance à l'effort. 1- Pathogénie et approche diagnostique
Art, Tatiana ULg; Amory, Hélène ULg; Lekeux, Pierre ULg

in Pratique Vétérinaire Equine (2000), 32

The muscular condition, rhabdomyolysis, may cause exercise intolerance in the sporting horse. When the condition is recurring, it is often difficult for the equine practitioner to establish the clinical ... [more ▼]

The muscular condition, rhabdomyolysis, may cause exercise intolerance in the sporting horse. When the condition is recurring, it is often difficult for the equine practitioner to establish the clinical diagnosis (is the horse suffering from rhabdomyolysis or not ?) and the aetiology (what is/are the cause(s) of the condition ?) and also to provide an effective treatment [less ▲]

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See detailL'influence de l'article 6 de la Convention européenne des droits de l'homme sur la procédure pénale belge
Jacobs, Ann ULg; Berbuto, Sandra

in Revue de Droit International et de Droit Comparé (2000)

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See detailBeyond Prejudice as Antipathy: Hostile and Benevolent Sexism Across Cultures
Glick, Peter; Fiske, Susan T.; Mladinic, Antonio et al

in Journal of Personality & Social Psychology (2000), 79(5), 763-775

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See detailInfo-congres. L'etude "MIRACL" ou "Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering".
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(12), 1064-6

The results of the "MIRACL" trial ("Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering") were presented at the recent annual meeting of the American Heart Association in New Orleans last ... [more ▼]

The results of the "MIRACL" trial ("Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering") were presented at the recent annual meeting of the American Heart Association in New Orleans last November 2000. This study demonstrates that atorvastatin, at a daily dose of 80 mg starting within the first 24 to 96 hours after an acute coronary event (unstable angina or non-Q-wave acute myocardial infarction) and maintained for 4 months, improves the cardiovascular prognosis by decreasing the combined risk of death (any cause), nonfatal myocardial infarction, resuscitated cardiac arrest and worsening angina with new objective evidence of ischemia requiring urgent hospitalization (-16% versus placebo, p < 0.05). [less ▲]

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See detailThe influence of facial emotion displays gender, and ethnicity on judgments of dominance and affiliation
Hess, U; Blairy, Sylvie ULg; Kleck, R

in Journal of Nonverbal Behavior (2000), 24(4), 265-283

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See detailIs the external beam PIXE method suitable for determining ancient silver artifact fineness?
Weber, Georges ULg; Guillaume, J.; Strivay, David ULg et al

in Nuclear Instruments & Methods in Physics Research Section B (2000), 161

In archeometry, the non-destructive characteristic of an analytical method is always very attractive. For most of techniques, besides the need of sampling, difficulties can originate from the shape and ... [more ▼]

In archeometry, the non-destructive characteristic of an analytical method is always very attractive. For most of techniques, besides the need of sampling, difficulties can originate from the shape and the size of the silver artifacts to be analyzed. The external PIXE method should be an answer to this problem but several questions are arising from the implementation of the technique to such a material. The aim of this paper is to specify the experimental procedure as to take into account several parameters, which could induce dramatic errors. Among them it can be pointed out the superficial enrichment in silver, arising from the dissolution of copper and copper oxide, the surface roughness effects, the great importance of the stability of the geometric conditions. The accuracy and the precision of the method are considered within the scope of the results obtained in ancient times by the cupellation with ashbone cupels. In addition. the process involved to obtain silver alloys has been studied in order to define its influence on the real fineness of the objects. (C) 2000 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailPomme: maladies de conservation. La lutte biologique au moyen de deux souches de levures.
Jijakli, Mohamed ULg

in Arboriculture Fruitiere (2000), (539), 19-23

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See detailNew strategy for the validation of chromatographic bioanalytical methods
Chapuzet, E.; Mercier, N.; Bervoas-Martin, S. et al

in STP Pharma Pratiques (2000), 10(1), 21-38

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See detailThickness effects on the pinning by columnar defects
Silhanek, Alejandro ULg; Guimpel, J.; Civale, L. et al

in Physica C: Superconductivity (2000), 341(Part 2), 1217-1218

We compare the angular dependence of the pinning of equivalent columnar defects in GdBa2Cu2O7 thin films and a thicker YBa2Cu3O7 single crystal. The tracks' related enhancement of the critical currents is ... [more ▼]

We compare the angular dependence of the pinning of equivalent columnar defects in GdBa2Cu2O7 thin films and a thicker YBa2Cu3O7 single crystal. The tracks' related enhancement of the critical currents is much smaller for the case of the thin films. We interpret this thickness dependence as resulting from a competition between the pinning of the correlated structures, related to total sample thickness, and surface boundary conditions, which force the vortices to depin from the columnar defects near the sample surface. [less ▲]

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See detailLa rédaction cartographique des spatiocartes
Donnay, Jean-Paul ULg; Cornélis, Bernard

in Bulletin de la Société Géographique de Liège (2000), 38

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