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See detailQuantitative bacterial cultures and cytological examination of bronchoalveolar lavage specimens in the diagnosis of lower respiratory tract disease in dogs: a retrospective study of 48 cases.
Peeters, Dominique ULg; McKierman, B.; Weisiger, R. et al

in Journal of Veterinary Internal Medicine (2000), 14(5), 534-541

Cytology and quantitative bacterial cultures of lower respiratory tract secretions are widely used in human medicine to differentiate airway infection from simple bacterial colonization. A retrospective ... [more ▼]

Cytology and quantitative bacterial cultures of lower respiratory tract secretions are widely used in human medicine to differentiate airway infection from simple bacterial colonization. A retrospective study was conducted to determine the usefulness of quantitative aerobic cultures and Gram stain intracellular bacteria counts from bronchoalveolar lavage (BAL) specimens in dogs in diagnosing lower respiratory tract infection (LRTI) and to determine whether chronic bronchitis is associated with marked bacterial growth in dogs. The threshold determined to define clinically relevant bacterial growth was 1.7 x 10(3) colony-forming units per milliliter of BAL fluid. We used this threshold and found that diagnostic sensitivity and specificity were 86% and 100%, respectively. With a threshold for infection of >2 intracellular bacteria observed in any of 50 fields, microscopic examination of Gram stain BAL preparations had a sensitivity of 71% and a specificity of 97% in establishing LRTI. There was a high correlation between bacterial morphology on BAL Gram stain and bacterial cultures. Combining the results of intracellular bacteria counts from the BAL Gram stain with those from the quantitative cultures, the sensitivity in diagnosing LRTI was 87% and the specificity was 97%. BAL quantitative cultures as well as quantitating intracellular bacteria on Gram stain BAL cytology were revealed to be useful in identifying LRTI in dogs. Chronic bronchitis does not appear to be associated with marked bacterial growth in dogs. [less ▲]

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See detailHigh-Performance Anion-Exchange Chromatography - Dad As A Tool For The Identification And Quantification Of Oligogalacturonic Acids In Pectin Depolymerisation
Deconinck, Thomas J.-M.; Ciza, Antoine; Sinnaeve, Georges et al

in Carbohydrate Research (2000), 329(4),

High-performance anion-exchange chromatography (HPAEC) coupled with a diode array detector (DAD) was used to identify and quantify oligogalacturonic acid components in pectins. Purified pectin lyase and ... [more ▼]

High-performance anion-exchange chromatography (HPAEC) coupled with a diode array detector (DAD) was used to identify and quantify oligogalacturonic acid components in pectins. Purified pectin lyase and polygalacturonase were used to generate unsaturated and saturated oligomers from pectins and sodium polygalacturonate, respectively. This method resulted in a good separation of saturated and unsaturated oligomers up to DP 13. It allowed us to follow polygalacturonase and pectate lyase depolymerisation pathways simultaneously. [less ▲]

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See detailL'éclairage : à nouveaux critères, nouveaux outils de mesure, de calcul et de simulation
Eugène, Christian; Rombauts, Patrick; Embrechts, Jean-Jacques ULg et al

in Revue de l'Electricité et de l'Electronique (2000), 7

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See detailLa carte des émotions : exercice structuré
Faulx, Daniel ULg

in Cahiers Internationaux de Psychologie Sociale (2000), (45), 98-103

Cet outil permet d'identifier et d'analyser la présence, la circulation et la gestion des émotions au sein d'une équipe de travail ou d'un groupe. Il propose différents modes de mesure de l'émotion au ... [more ▼]

Cet outil permet d'identifier et d'analyser la présence, la circulation et la gestion des émotions au sein d'une équipe de travail ou d'un groupe. Il propose différents modes de mesure de l'émotion au sein des groupes, et constitue à ce titre à la fois un outil de mesure et d'intervention ou de développement. [less ▲]

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See detailRole of Tir and Intimin in the Virulence of Rabbit Enteropathogenic Escherichia coli (REPEC) Serotype O103:H2
Marchès, O.; Nougayrede, J. P.; Boullier, S. et al

in Infection and Immunity (2000), 68

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See detailEclipse totale du 11 août 1999 et évolution de la basse ionosphère
Delcourt, J. J.; Jodogne, J.-C.; Biémont, Emile ULg

in Ciel et Terre (2000), 116(1), 6-7

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See detailUnimolecular reaction dynamics from kinetic energy release distributions. VI. Energy-selected ions
Lorquet, Jean-Claude ULg

in International Journal of Mass Spectrometry (2000), 201(1-3), 59-67

The kinetic energy distribution (KERD) determined by Brand et al. [Chem. Phys. 76 (1983) 111] for the iodine loss from energy-selected iodopropane ions has been analyzed by the maximum entropy method. The ... [more ▼]

The kinetic energy distribution (KERD) determined by Brand et al. [Chem. Phys. 76 (1983) 111] for the iodine loss from energy-selected iodopropane ions has been analyzed by the maximum entropy method. The entropy deficiency DS has been determined and the value of e(-DS), which measures the efficiency of phase-space sampling, has been found equal to about 96%, thus corresponding to a nearly fully statistical situation. The phase space theory of Klots describes a slightly more constrained situation with e(-DS) ≃ 77%. A rapid determination of the sampled fraction of phase space is possible from energy-selected KERDs, based on the fact that there exists a direct relationship between the efficiency e(-DS) and the reduced maximum of the KERD ε(red)/(M) = ε(M) (E)/<ε>(E). The product ε(M)(E) P(ε(M)/E) or ε(red)/(M) P(ε(red)/(M)) holds the same property. (C) 2000 Elsevier Science B.V. [less ▲]

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See detailRéhabilitation du pont barrage de Montignie-Saint-Christophe
Lejeune, André ULg; Pirotton, Michel ULg

in Cahiers de l'Urbanisme (Les) (2000)

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See detailEvidence-based medicine. Apport des etudes epidemiologiques.
REGINSTER, Jean-Yves ULg; BETZ, Romain ULg

in Revue Médicale de Liège (2000), 55(4), 211-5

Epidemiological studies, more specifically those related to analytical epidemiology are a major determinant of evidence-based medicine. When classifying the value of the different epidemiological studies ... [more ▼]

Epidemiological studies, more specifically those related to analytical epidemiology are a major determinant of evidence-based medicine. When classifying the value of the different epidemiological studies, based on their level of causality, cohort studies are ranked higher than case-control studies, mainly due to the fact that they allow direct collection of information on exposition to risk factors and health consequences. However, case-control studies can also provide an important information, if a specific effort is dedicated to the analyses of the circumstances of the exposition. Meta-analysis increases, by pooling them, the statistical power of individual studies of limited size. Meta-analysis can also be considered as an important source of evidence in the perspective of evidence-based medicine. [less ▲]

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See detailRésultats d'une enquête internationale en mathématiques
Monseur, Christian ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), (3-4), 13-20

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See detailLaparascopic management of a unicornuate uterus with two cavitated, non-communicating rudimentary horns
NISOLLE, Michelle ULg; Donnez, Jacques

in Human Reproduction (2000), 15(8), 1873-4

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See detailUse of stable isotope to delineate amphipod trophic status in Antarctic food webs
Nyssen, Fabienne ULg

in Polish Archives of Hydrobiology (2000), 47

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See detailConstruction and characterization of an ovine BAC contig spanning the callipyge locus.
SEGERS, Karin ULg; Vaiman, D.; Berghmans, S. et al

in Animal Genetics (2000), 31(6), 352-9

We describe the construction of an ovine BAC contig spanning a 4.6 centimorgan (cM) chromosome segment known to contain the callipyge (CLPG) locus. The contig comprises 21 ovine BAC clones jointly ... [more ▼]

We describe the construction of an ovine BAC contig spanning a 4.6 centimorgan (cM) chromosome segment known to contain the callipyge (CLPG) locus. The contig comprises 21 ovine BAC clones jointly covering approximately 900 kilobases (Kb). Two gaps in the BAC contig, spanning 10 and 7.5 Kb, respectively, were bridged by long range PCR. The corresponding chromosome region was shown to be characterized by an unusually low Kb to cM ratio (164 Kb/cM) and a high density of Not1 sites (1:126 Kb) possibly reflecting a high gene density in the corresponding chromosome region. Equivalent amplification of 64 sequence tagged sites spanning the corresponding region from homozygous +/+ and CLPG/CLPG individuals disproves the hypothesis of a major deletion causing the CLPG mutation. [less ▲]

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See detailTilted Peptides: A Motif For Membrane Destabilization (Hypothesis)
Brasseur, Robert ULg

in Molecular Membrane Biology (2000), 17(1), 31-40

Cell life depends on the dynamics of molecular processes: molecule folding, organelle building and transformations involving membrane fusion, protein activation and degradation. To carry out these ... [more ▼]

Cell life depends on the dynamics of molecular processes: molecule folding, organelle building and transformations involving membrane fusion, protein activation and degradation. To carry out these processes, the hydrophilic/hydrophobic interfaces of amphipathic systems such as membranes and native proteins must be disrupted. In the past decade, protein fragments acting in the disruption of interfaces have been evidenced: they are named the tilted or oblique peptides. Due to a peculiar distribution of hydrophobicity, they can disrupt hydrophobicity interfaces. Tilted peptides should be present in many proteins involved in various stages of cell life. This hypothesis overviews their discovery, describes how they are detected and discusses how they could be involved in dynamic biological processes. [less ▲]

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See detailPLAG1, the main translocation target in pleomorphic adenoma of the salivary glands, is a positive regulator of IGF-II.
Voz, Marianne ULg; Agten, N. S.; Van de Ven, W. J. et al

in Cancer Research (2000), 60(1), 106-13

PLAG1, a novel developmentally regulated C2H2 zinc finger gene, is consistently rearranged and overexpressed in pleomorphic adenomas of the salivary glands with 8q12 translocations. In this report, we ... [more ▼]

PLAG1, a novel developmentally regulated C2H2 zinc finger gene, is consistently rearranged and overexpressed in pleomorphic adenomas of the salivary glands with 8q12 translocations. In this report, we show that PLAG1 is a nuclear protein that binds DNA in a specific manner. The consensus PLAG1 binding site is a bipartite element containing a core sequence, GRGGC, and a G-cluster, RGGK, separated by seven random nucleotides. DNA binding is mediated mainly via three of the seven zinc fingers, with fingers 6 and 7 interacting with the core and finger 3 with the G-cluster. In transient transactivation assays, PLAG1 specifically activates transcription from its consensus DNA binding site, indicating that PLAG1 is a genuine transcription factor. Potential PLAG1 binding sites were found in the promoter 3 of the human insulin-like growth factor II (IGF-II) gene. We show that PLAG1 binds IGF-II promoter 3 and stimulates its activity. Moreover, IGF-II transcripts derived from the P3 promoter are highly expressed in salivary gland adenomas overexpressing PLAG1. In contrast, they are not detectable in adenomas without abnormal PLAG1 expression nor in normal salivary gland tissue. This indicates a perfect correlation between PLAG1 and IGF-II expression. All of these results strongly suggest that IGF-II is one of the PLAG1 target genes, providing us with the first clue for understanding the role of PLAG1 in salivary gland tumor development. [less ▲]

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See detailRecombinant prolactin Receptor Extracellular Domain of Rainbouw trout (Oncorhynchus mykiss): subcloning, preparation and characterization
Sandowski, Y.; Cohen, Y.; Le Rouzic, P. et al

in General and Comparative Endocrinology (2000), 118

The cDNA of the extracellular domain of rainbow trout (Oncorhynchus mykiss) prolactin receptor (trPRLR-ECD) was cloned in the prokaryotic expression vector pMON to enable its expression in Escherichia ... [more ▼]

The cDNA of the extracellular domain of rainbow trout (Oncorhynchus mykiss) prolactin receptor (trPRLR-ECD) was cloned in the prokaryotic expression vector pMON to enable its expression in Escherichia coli after induction with nalidixic acid. The bacterially expressed trPRLR-ECD protein, contained within the refractile body pellet, was solubilized in 4.5 M urea, refolded, and purified on a Q-Sepharose column, pH 8, by stepwise elution with NaCl. The bioactive monomeric 26-kDa fraction was eluted in 0.2 M NaCl, yielding 20 mg/2.5 L of induced culture. The purified protein was over 98% homogeneous, as shown by SDS-PAGE in the presence or absence of reducing agent and by chromatography on a Superdex column. Binding experiments using [125I]ovine placental lactogen (oPL) as a ligand revealed that human growth hormone (hGH), oPL, and ovine prolactin (oPRL) were the most effective competitors, with respective IC50 values of 1.32, 2.27, and 2.70 nM. Chicken (ch) PRL did not compete at all, and homologous trPRL was much less effective, with a corresponding IC50 value of 1826 nM. Gel-filtration was used to determine the stoichiometry of trPRLR-ECD's interaction with oPL, hGH, and oPRL. Only oPL yielded a 2:1 complex, whereas hGH and oPRL formed only 1:1 complexes, with excess trPRLR-ECD being seen at the initial 2:1 trPRLR-ECD:hGH or trPRLR-ECD:oPRL ratios. No studies were performed with chPRL because of its inability to compete with [125I]oPL or with trPRL because of its low affinity toward trPRLR-ECD. The present results agree with previous findings indicating, as in mammals, that homologous PRL interacts transiently with its receptor and suggest that transient homologous PRL-induced homodimerization of the receptor is sufficient to initiate a biological signal, despite the fact that, in classical binding experiments, only low specific binding can be detected. [less ▲]

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See detailGenetic Knowledge and Social Marginalization in the People's Republic of China
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2000), Vol. XVII

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See detailGeometric quantities associated to differential operators
Mathonet, Pierre ULg

in Communications in Algebra (2000), 28(2), 699-718

Denote by F_lambda the space of fields of tensor densities of weight -lambda over a manifold M. The space D^p_{lambda,mu} of differential operators of order at most p that map F_lambda onto F_mu are ... [more ▼]

Denote by F_lambda the space of fields of tensor densities of weight -lambda over a manifold M. The space D^p_{lambda,mu} of differential operators of order at most p that map F_lambda onto F_mu are modules over the Lie algebra of vector fields Vect(M). We compute all the Vect(M)-invariant mappings from D^p_{lambda,mu} onto F_nu. [less ▲]

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See detailDevelopment Of An In Vitro Pod Culture Technique For Young Pods Of Phaseolus Vulgaris L.
Geerts, P.; Sassi, K.; Mergeai, Guy ULg et al

in In Vitro Cellular & Developmental Biology-Plant (2000), 36(6),

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See detailPharma clinics. Le medicament du mois. La cerivastatine (Lipobay, Cholstat).
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(2), 117-20

Cerivastatin, commercialized under the trade names of Lipobay by Bayer and Cholstat by Fournier Pharma, is a new synthetic statin. Because of its high affinity for HMG-CoA reductase enzyme that it ... [more ▼]

Cerivastatin, commercialized under the trade names of Lipobay by Bayer and Cholstat by Fournier Pharma, is a new synthetic statin. Because of its high affinity for HMG-CoA reductase enzyme that it specifically and selectively inhibited in the hepatocytes, cerivastatin exerts its cholesterol-lowering effect at very low doses, between 0.1 and 0.3 mg/day. Cerivastatin is indicated, after diet failure, in the treatment of primary forms of isolated hypercholesterolaemia or combined hyperlipidaemia. It is presented by the two pharmaceutical companies as 0.1, 0.2 and 0.3 mg filmed tablets. Usual dose is 0.3 mg, once daily, to be reduced in presence of renal failure. Cerivastatin is metabolised within the liver by two different families of cytochrome P450, which limits the risk of drug interferences. Besides this potential advantage as compared with some other statins, its pharmacodynamic activity and safety profile seem to be similar to those of other agents of the same pharmacological family. [less ▲]

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See detailLes souches pathogènes d'Escherichia coli chez les chiens et chats : II) Données cliniques et bactériologiques sur les souches entéropathogènes
Mainil, Jacques ULg; Janssen, L.; Charlier, G. et al

in Annales de Médecine Vétérinaire (2000), 144

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See detailLe maître de Waha : un exemple de développement durable
Van Ruymbeke, Muriel ULg

in De la Meuse à l'Ardenne (2000), (31), 104-106

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See detailWegwijs in de vele benamingen van de veelvormige pathogeen Escherichia coli
Mainil, Jacques ULg

in Vlaams Diergeneeskundig Tijdschrift (2000), 69

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See detailPlatypsyllus castoris Ritsema, 1869 (Coleoptera, Leptinidae), espèce nouvelle pour la faune de Belgique
Libois, Roland ULg

in Bulletin de la Société Royale Belge d'Entomologie = Bulletin van de Koninklijke Belgische Vereniging voor Entomologie (2000), 136(1), 30-31

This paper reports for the first time, the presence of Platypsyllus castoris Rits. in Belgium. The insects were collected on a road killed European beaver found in Anseremme (Dinant) in December 1999 ... [more ▼]

This paper reports for the first time, the presence of Platypsyllus castoris Rits. in Belgium. The insects were collected on a road killed European beaver found in Anseremme (Dinant) in December 1999. This beaver is one of those that were recently illegaly reintroduced in various parts of southern Belgium. [less ▲]

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See detailTheoretical Oscillator Strengths in Pr III and application to some CP stars
Palmeri, P.; Quinet, Pascal ULg; Frémat, Y. et al

in Astrophysical Journal Supplement Series (2000), 129

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See detailIntégration du transfert de rugosité à un modèle de laminage à froid
Collette, Caroline; Counhaye, Christian; Ponthot, Jean-Philippe ULg

in Revue de Métallurgie [=Revue de Métallurgie. Cahiers d'Informations Techniques] (2000)

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See detailL'entérotoxémie bovine en Belgique. II. Epizootiologie élémentaire et pathologie descriptive.
Manteca, Christophe; Daube, Georges ULg; Jauniaux, Thierry ULg et al

in Annales de Médecine Vétérinaire (2000), 145

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See detailIschaemic Colitis Following Aortoiliac Surgery
VAN DAMME, Hendrik ULg; CREEMERS, Etienne ULg; Limet, Raymond ULg

in Acta Chirurgica Belgica (2000), 100(1), 21-7

Ischaemic colitis following aortoiliac surgery is a feared complication. Its frequency varies from 7% after repair of ruptured abdominal aortic aneurysm (AAA) to 0.6% after bypass for aortoiliac occlusive ... [more ▼]

Ischaemic colitis following aortoiliac surgery is a feared complication. Its frequency varies from 7% after repair of ruptured abdominal aortic aneurysm (AAA) to 0.6% after bypass for aortoiliac occlusive disease (AOD). In order to analyse predisposing factors and outcome of ischaemic colitis, the authors reviewed their clinical experience from 1988 to 1998. It concerns 28 cases (16 ruptured AAA, 7 elective AAA, 5 OAD) of clinically evident colonic ischaemia. This means an incidence of 7% after repair of ruptured AAA, 0.6% after elective AAA repair, and 0.8% after bypass for AOD. Transmural necrosis (grade 3) was observed in 21 patients, grade 2 ischaemia in 5 patients, and grade 1 ischaemia in 2 patients. Fifteen patients with grade 3 ischaemia underwent colectomy (Hartmann's procedure) with a mortality rate of 66%. All non operated grade 3 patients died. Overall, 16 of the 28 patients died at hospital (57% mortality rate). None of the patients with mild (grade 2 or 1) colonic ischaemia died. Profound hypovolaemic shock and inflammatory AAA were the only significant predisposing factors leading to colonic ischaemia. Associated colon revascularization could not avoid the evolution to colon necrosis in four patients. Reimplantation of a patent inferior mesenteric artery or an internal iliac artery was performed in only 4.8% of all aortoiliac reconstructions, and did not influence the development of ischaemic colitis. The authors conclude that a more liberal use of postoperative sigmoidoscopy could allow detecting colonic ischaemia at an earlier stage and reduce ensuing mortality. A reinforced effort to restore or preserve colonic vascularization could lower the incidence of colonic ischaemia following aortoiliac surgery. [less ▲]

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See detailPierre Bourdieu: Die Regeln der Kunst : Genese und Struktur des literarischen Feldes
Viehöver, Vera ULg

in Philosophischer Literaturanzeiger (2000), 53(4), 344-349

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See detailNew strategy for the validation of chromatographic bioanalytical methods
Chapuzet, E.; Mercier, N.; Bervoas-Martin, S. et al

in STP Pharma Pratiques (2000), 10(1), 21-38

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See detailCompétition et choix du partenaire sexuel chez les primates
Huynen, Marie-Claude ULg

in Cahiers d'Ethologie (2000), 20(1), 85-112

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See detailTheoretical analysis of a dynamic thermoconvective pattern in a circular container
Dauby, Pierre ULg; Colinet, Pierre; Johnson, Duane

in Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (2000), 61(3), 2663-2668

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See detailEffet du couvert forestier sur la précison d'un système de positionnement global différentiel (dGPS)
Lejeune, Philippe ULg; Hellemans, Philippe

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(1), 41-49

Effect of forest canopy on the accuracy of a differential global positioning system (dGPS). The possibilities to use dGPS for forest mapping are analysed. The efficiency of dGPS in forest condition is ... [more ▼]

Effect of forest canopy on the accuracy of a differential global positioning system (dGPS). The possibilities to use dGPS for forest mapping are analysed. The efficiency of dGPS in forest condition is linked to canopy interference, which intercepts signals sent by some of the satellites or reflect them (multipathing). Two types of equipment have been tested : a TrimbleTM Svee Six coupled with a RDS differential receiver and a Trimble SK8 coupled with an OMNISTAR differential receiver. Recordings have been achieved according to two modes : static (recording on one spot during one minute) and cinematic (moving continuously along the stand limits). Two types of forest canopy were compared : light canopy made of young poplar plantation with few obstacles in the vicinity, and closed canopy of mature spruce stand edged with other mature stand. Cinematic mode efficiency is higher than static one (mean errors are respectively 3.1 m and 9.1 m). In the same way positioning is more accurate for the stand with light canopy than for the other one (mean errors are respectively 2.9 m and 9.4 m). Difference between recording modes are probably due to multipathing effect that filtering algorithm integrated in the GPS receivers are not able to remove in static mode. The efficiency of differential signal reception is also different for the two stands : 1.3 % and 20.5 % of missing differential signal respectively in the light and dense canopy conditions. [less ▲]

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See detailMieux connaître la forêt privée. Appel aux propriétaires.
Rondeux, Jacques ULg; Bourland, Nils ULg

in Silva Belgica (2000), 107(1), 28-29

Dans le cadre de l'appui scientifique à l'Inventaire permanent des Ressources ligneuses de Wallonie, l'Unité de Gestion et Economie forestières (Prof. J. RONDEUX) de la Faculté universitaire des Sciences ... [more ▼]

Dans le cadre de l'appui scientifique à l'Inventaire permanent des Ressources ligneuses de Wallonie, l'Unité de Gestion et Economie forestières (Prof. J. RONDEUX) de la Faculté universitaire des Sciences agronomiques de Gembloux (FUSAGx) a été chargée de compléter l'information générale relative à la forêt privée, en particulier pour mieux identifier son degré de morcellement et l'évolution attendue de celui-ci dans un avenir proche. Ce travail est réalisé en étroite collaboration avec la Cellule Inventaire des Ressources ligneuses Wallonnes (Ir. H. LECOMTE) et bénéficie du soutien de la Société Royale Forestière de Belgique. [less ▲]

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See detailImpact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: a free-response ROC analysis.
Hustinx, Roland ULg; Dolin, R. J.; Benard, F. et al

in European Journal of Nuclear Medicine (2000), 27(9), 1365-71

The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating ... [more ▼]

The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating characteristic (FROC) methodology. Thirty-four patients with various abdominal tumors were evaluated (11 men, 23 women, median age 48 years). Whole-body emission scans were performed 68 min (35-102 min) after intravenous injection of 4.3 MBq/kg fluorine-18 fluorodeoxyglucose (FDG). Images were reconstructed using the OS-EM algorithm and corrected for attenuation either using postinjection singles transmission (n=27) or by calculation and body outline (n=7). Total scan duration did not exceed 70 min. Studies were read independently by four observers unaware of any clinical data. The uncorrected (UC) images were systematically read before the attenuation-corrected (AC) images. All studies were given an image quality score ranging from 1 (unreadable) to 5 (excellent). Each focus of increased activity was then localized and given a probability of malignancy using a five-point scale. The average image quality score was similar for both UC and AC images. At the time of the positron emission tomography (PET) scans, 127 lesions (63 liver metastases, 9 retroperitoneal lesions, 50 peritoneal or bowel lesions, and 5 pancreatic carcinomas) were revealed by pathological or correlative studies. The areas under the FROC curves were consistently greater for AC images (range 0.8663-0.8867) than for UC images (range 0.7774 -0.8613). Overall, the difference between the AC images and the UC images was significant (P=0.019). In particular, correction for attenuation increased the sensitivity regardless of the location of the lesions. In conclusion, correction for attenuation significantly improves the diagnostic accuracy of FDG-PET for abdominal staging of neoplasms, without impairing the image quality. [less ▲]

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See detailLe Sart Tilman et Louvain-la-Neuve
Frankignoulle, Pierre ULg

in Cahiers de l'Urbanisme (Les) (2000), 28-29

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See detailLe principe de precaution et l'obligation d'action medicale
Foidart, Jean-Michel ULg

in Bulletin de l'Académie Nationale de Médecine (2000), 184(5), 937-43943-4

Since Antiquity, medicine has been based upon the principle of prudence. In recent years, the principle of precaution has stolen over the medical conscience and has especially been forced on doctors under ... [more ▼]

Since Antiquity, medicine has been based upon the principle of prudence. In recent years, the principle of precaution has stolen over the medical conscience and has especially been forced on doctors under pressure from a Society searching for a new Holy Grail; the utopia of zero risk and the fear for magical power of an omnipotent medicine. The principle of precaution should be capable of warding off all these evils of techno-scientific progress applied to Health. Thus, in a few years, a new norm has established itself first for the environment but which has today extended to the domain of medical decisions. It is essential that the medical authorities attract the attention of politics and of the judiciary to the dangers of blindly transposing the principle of precaution in ecology to the world of medicine. The risks of deviation are numerous, the eventual perverse effects would be detrimental to patients and health security would be endangered by paralysis and conservatism. Medicine is neither the Art of Curing nor the Art of not Harming, ... it is the Art of Caring! ... [less ▲]

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See detailRural Labor Flows in China
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2000), Vol. XVIII

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See detailErythropoiesis and renal transplant pregnancy.
Magee, L. A.; von Dadelszen, P.; Darley, J. et al

in Clinical Transplantation (2000), 14(2), 127-35

OBJECTIVE: To examine erythropoiesis in renal transplant pregnancies. METHODS: Retrospective cohort study of 30 renal transplant cases and 30 age, smoking and parity-matched healthy controls with normal ... [more ▼]

OBJECTIVE: To examine erythropoiesis in renal transplant pregnancies. METHODS: Retrospective cohort study of 30 renal transplant cases and 30 age, smoking and parity-matched healthy controls with normal index pregnancy. Retrospective chart review and assay of frozen antenatal serum (for serum erythropoietin concentration [serum EPO]), transferrin receptor protein [TfR], ferritin, folate and B12) were performed. The linear regression equation for normal pregnancy controls was used to calculate predicted [serum EPO] and the observed/predicted (O/P) log [serum EPO] was plotted. The relationship between [serum EPO] and haemoglobin (Hb) among transplant cases was considered to be different from that among controls if the slope of the O/P log [serum EPO] versus Hb regression was significantly different from zero. RESULTS: The transplant (14 cadaveric) to conception interval was (median [range]) 33.5 [4, 189] months. Immunosuppressants were azathioprine (n = 25), cyclosporine (n = 22) and/or prednisone (n = 25). Cases were more often primiparous (20 vs. 7 [controls]; p = 0.01), had pre-existent hypertension (20 vs. 0 [controls]; p < 0.001), developed new/increased hypertension or pre-eclampsia (28 vs. 0 [controls]; p < 0.001) and an antenatal rise in creatinine (14 vs. 2 [controls]; p < 0.001). In early pregnancy, cases had similar EPO (15.2 [2.6, 84.6] vs. 15.7 [6.4, 41.0] [controls] U/L) but lower Hb (101 [65, 129] vs. 116 [106, 150] g/L; p < 0.001). Twenty-two (73%) cases had Hb < 100 g/L (vs. 4 [controls]; p < 0.0001); Hb was comparable at 6 wk postpartum. With advancing gestational age (GA), Hb remained stable and serum EPO increased in both groups. The slope of the O/P log [serum EPO] versus Hb for transplant cases was significantly different from zero within both the 17-28 wk (slope +/- SEM: 0.010 +/- 0.002; p < 0.0001) and the 29-42 wk GA categories (0.006 +/- 0.003; p = 0.02). Cases showed smaller rises in serum TfR (change 481 [- 1471, 2780]) vs. 1119 [- 698, 4195] [controls] ng/mL; p = 0.005). CONCLUSIONS: Anaemia frequently complicates renal transplant pregnancies, in which serum EPO is inappropriately low and the rate of erythropoiesis blunted. [less ▲]

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See detailFracture prevention. New topic
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Clinical Evidence (2000), 4

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See detailTransition rates of the resonance line doublet in the Cl I sequence, Ar II to Ge XVI
Biémont, Emile ULg; Träbert, E.

in Journal of Physics : B Atomic Molecular & Optical Physics (2000), 33

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See detailPredictive value of ovarian endometriosis?
NISOLLE, Michelle ULg; Donnez, Jacques

in Fertility and Sterility (2000), 73(2), 419-20

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See detailEvidence-Based Medicine: traitement de l'hépatite chronique C. GLEVHE. Groupe Liégeois d'Etude des Virus Hépatotropes.
Delwaide, Jean ULg; Gerard, Christiane ULg; Belaiche, Jacques ULg et al

in Revue Médicale de Liège (2000), 55(5), 337-340

The Hepatitis C virus (HCV) infects nearly 170 million people in the world. The major characteristic of virus C is its tendency to chronicity in more than 85% of cases. Generally asymptomatic, HCV ... [more ▼]

The Hepatitis C virus (HCV) infects nearly 170 million people in the world. The major characteristic of virus C is its tendency to chronicity in more than 85% of cases. Generally asymptomatic, HCV infection may also evolve with time to cirrhosis and hepatocellular carcinoma. During the last few years, HCV-related end-stage cirrhosis has become the first cause of liver transplantation. In 10 years only, very significant progress has been made in the knowledge of the virus, not only in the field of diagnosis but also in therapy. Several consensus conferences taking last discoveries into account have been organized in order to promote recommendations useful for the management of hepatitis C patients. The aim of this short overview is to summarize practical recommendations that emerged recently from consensus meetings. [less ▲]

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See detailHarcèlement moral au travail. Etat des lieux et pistes de développement.
Faulx, Daniel ULg; Geuzaine, Caroline

in Médecine du Travail & Ergonomie= Arbeidsgezondheidszorg & Ergonomie (2000), 37(3), 135-147

Revue théorique critique et analyse de littérature sur le harcèlement moral

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See detailCrystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family.
Bompard-Gilles, C.; Remaut, H.; Villeret, V. et al

in Structure (2000), 8(9), 971-80

BACKGROUND: beta-Lactam compounds are the most widely used antibiotics. They inactivate bacterial DD-transpeptidases, also called penicillin-binding proteins (PBPs), involved in cell-wall biosynthesis ... [more ▼]

BACKGROUND: beta-Lactam compounds are the most widely used antibiotics. They inactivate bacterial DD-transpeptidases, also called penicillin-binding proteins (PBPs), involved in cell-wall biosynthesis. The most common bacterial resistance mechanism against beta-lactam compounds is the synthesis of beta-lactamases that hydrolyse beta-lactam rings. These enzymes are believed to have evolved from cell-wall DD-peptidases. Understanding the biochemical and mechanistic features of the beta-lactam targets is crucial because of the increasing number of resistant bacteria. DAP is a D-aminopeptidase produced by Ochrobactrum anthropi. It is inhibited by various beta-lactam compounds and shares approximately 25% sequence identity with the R61 DD-carboxypeptidase and the class C beta-lactamases. RESULTS: The crystal structure of DAP has been determined to 1.9 A resolution using the multiple isomorphous replacement (MIR) method. The enzyme folds into three domains, A, B and C. Domain A, which contains conserved catalytic residues, has the classical fold of serine beta-lactamases, whereas domains B and C are both antiparallel eight-stranded beta barrels. A loop of domain C protrudes into the substrate-binding site of the enzyme. CONCLUSIONS: Comparison of the biochemical properties and the structure of DAP with PBPs and serine beta-lactamases shows that although the catalytic site of the enzyme is very similar to that of beta-lactamases, its substrate and inhibitor specificity rests on residues of domain C. DAP is a new member of the family of penicillin-recognizing proteins (PRPs) and, at the present time, its enzymatic specificity is clearly unique. [less ▲]

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See detailLandscape fragmentation assessment using a single measure.
Bogaert, Jan ULg; Van Hecke, P; Salvador-Van Eysenrode, D et al

in Wildlife Society Bulletin (2000), 28(4), 875-881

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See detailIs the external beam PIXE method suitable for determining ancient silver artifact fineness?
Weber, Georges ULg; Guillaume, J.; Strivay, David ULg et al

in Nuclear Instruments & Methods in Physics Research Section B (2000), 161

In archeometry, the non-destructive characteristic of an analytical method is always very attractive. For most of techniques, besides the need of sampling, difficulties can originate from the shape and ... [more ▼]

In archeometry, the non-destructive characteristic of an analytical method is always very attractive. For most of techniques, besides the need of sampling, difficulties can originate from the shape and the size of the silver artifacts to be analyzed. The external PIXE method should be an answer to this problem but several questions are arising from the implementation of the technique to such a material. The aim of this paper is to specify the experimental procedure as to take into account several parameters, which could induce dramatic errors. Among them it can be pointed out the superficial enrichment in silver, arising from the dissolution of copper and copper oxide, the surface roughness effects, the great importance of the stability of the geometric conditions. The accuracy and the precision of the method are considered within the scope of the results obtained in ancient times by the cupellation with ashbone cupels. In addition. the process involved to obtain silver alloys has been studied in order to define its influence on the real fineness of the objects. (C) 2000 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailA clinical comparison of sumatriptan nasal spray and dihydroergotamine nasal spray in the acute treatment of migraine.
Boureau, F.; Kappos, L.; Schoenen, Jean ULg et al

in International Journal of Clinical Practice (2000), 54(5), 281-6

A multinational, multicentre, randomised, double-blind, double-dummy, crossover study (368 patients treating two attacks) was conducted to compare the efficacy and tolerability of sumatriptan nasal spray ... [more ▼]

A multinational, multicentre, randomised, double-blind, double-dummy, crossover study (368 patients treating two attacks) was conducted to compare the efficacy and tolerability of sumatriptan nasal spray (20 mg) with dihydroergotamine (DHE) nasal spray (1 mg plus optional 1 mg). At the primary efficacy time point of 60 minutes after dosing, significantly more patients obtained headache relief (change from moderate or severe to none or mild) after treatment with sumatriptan than with DHE (53% sumatriptan, 41% DHE, p < 0.001). Significantly more patients reported relief of nausea after sumatriptan than after DHE at 60 minutes (64% sumatriptan, 49% DHE, p = 0.006). A significant difference between the two treatments was first observed at 45 minutes with respect to both headache relief (38% sumatriptan, 31% DHE, p = 0.037) and relief of nausea (55% sumatriptan, 40% DHE, p = 0.014). There were no significant differences between the two treatments for other measures of efficacy. Both treatments were well tolerated, with only 10% of patients in each group reporting one or more adverse events. The most frequently reported adverse event after sumatriptan was a bad or bitter taste, which was reported by 5% of patients. After DHE, 4% of patients reported symptoms of the nasal cavity/sinuses and 3% reported nausea and/or vomiting as adverse events. It is concluded that sumatriptan nasal spray is superior to DHE nasal spray in the relief of pain and nausea associated with acute migraine headache. [less ▲]

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See detailLa Francophonie à travers les médias africains. Le cas de la région des Grands Lacs africains
Kabamba, Bob ULg

in Studia Diplomatica (2000), Vol. LIII: 2000(n°3),

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See detailL'appareil aptychial chez les ammonoïdes.
Pierard, Sébastien ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Association des Géologues Amateurs de Belgique Minibul (2000), 33

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See detailPalladium-silver sol-gel catalysts for selective hydrodechlorination of 1,2-dichloroethane into ethylene II. Surface composition of alloy particles
Heinrichs, Benoît ULg; Noville, Francis ULg; Schoebrechts, Jean-Paul et al

in Journal of Catalysis (2000), 192(1), 108-118

The surface composition of alloy particles in Pd-Ag/SiO2 hydrodechlorination (HDC) sol-gel catalysts has been determined by combining three experimental techniques, carbon monoxide chemisorption, X-ray ... [more ▼]

The surface composition of alloy particles in Pd-Ag/SiO2 hydrodechlorination (HDC) sol-gel catalysts has been determined by combining three experimental techniques, carbon monoxide chemisorption, X-ray diffraction, and transmission electron microscopy, Values obtained through this method show a very marked silver enrichment of the surface, as expected: as a consequence of the important gap between palladium and silver surface energies. These values are in complete agreement with surface composition curves calculated in other studies by means of Auger electron spectroscopy and infrared spectroscopy. The influence of sample pretreatment temperature as well as the influence of carbon monoxide on surface composition are discussed. (C) 2000 Academic Press. [less ▲]

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See detailParticularités de la prise en charge de l’excès pondéral chez l’adolescent : résultats d’une enquête exploratoire
Glowacz, Fabienne ULg; Bourguignon, J. P.; Born, Michel ULg

in Bulletin d’Education du Patient (2000), 19(3), 132-140

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See detailLa rédaction cartographique des spatiocartes
Donnay, Jean-Paul ULg; Cornélis, Bernard

in Bulletin de la Société Géographique de Liège (2000), 38

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See detailFour-fold anisotropy of the basal plane magnetization of YNi2B2C: nonlocal effects
Civale, L.; Silhanek, Alejandro ULg; Thompson, J. R. et al

in Physica C: Superconductivity (2000), 341(Part 2), 1299-1300

We present studies of the vortex state magnetization M of a single crystal of the nonmagnetic borocarbide superconductor YNi2B2C. With magnetic field H applied in the square basal plane of the tetragonal ... [more ▼]

We present studies of the vortex state magnetization M of a single crystal of the nonmagnetic borocarbide superconductor YNi2B2C. With magnetic field H applied in the square basal plane of the tetragonal unit cell, M has a four-fold anisotropy. This pi /2 periodicity occurs deep in the superconductive mixed state, with an unusual field dependence, for a range of temperatures T < T-c. The observations are well explained by a generalized London model incorporating non-local electrodynamics, using parameters from complementary experiments. [less ▲]

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See detailEcological, morphological and allozymic differentiation between diploid and tetraploid knapweeds (Centaurea jacea) from a contact zone in the Belgian Ardennes
Hardy, O. J.; Vanderhoeven, SONIA ULg; De Loose, M. et al

in New Phytologist (2000), 146(2), 281-290

In the northeastern part of Belgium, the Centaurea jacea complex shows extensive morphological variation and is represented by a diploid (2n = 22) and a tetraploid (2n = 44) cytotype. Polysomic ... [more ▼]

In the northeastern part of Belgium, the Centaurea jacea complex shows extensive morphological variation and is represented by a diploid (2n = 22) and a tetraploid (2n = 44) cytotype. Polysomic inheritance of allozyme markers in the tetraploids, suggesting autopolyploidy, is here demonstrated for the first time. In order to test whether the tno cytotypes occupy distinct habitats and possess different gene pools, patterns of allozymic and morphological variation were investigated in relation to ploidy level and site characteristics in 26 populations from the Belgian Ardennes. The two cytotypes showed a parapatric distribution, the diploids occurring at higher elevations (mostly above 500 m) than the tetraploids (mostly below 500 m). Three mixed populations were found near the contact zone of the two cytotypes. Within the mixed populations no triploid plant and no evidence for gene flow between cytotypes were found, despite widely overlapping flowering periods. The two cytotypes can be distinguished on the basis of morphological traits and enzymatic gene pools. The congruence of morphological and allozymic variation with chromosome numbers suggests a secondary contact between the two cytotypes with limited gene flow between them. The origin and persistence of the parapatric distribution are discussed. [less ▲]

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See detailRiboflavin (vitamin B2) as a prophylactic treatment for migraine
Schoenen, Jean ULg

in Medical Updates on Therapy, Diagnosis and Prevention (2000), 2

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See detailLa station de l'Hermitage à Huccorgne: un habitat gravettien de plein-air en Belgique
Straus, Lawrence; Otte, Marcel ULg; Noiret, Pierre ULg et al

in Notae Praehistoricae (2000), 20

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See detailAssessment of postprandial hepatic glycogen synthesis from uridine diphosphoglucose kinetics in obese and lean non-diabetic subjects.
Paquot, Nicolas ULg; Schneiter, P.; Scheen, André ULg et al

in International Journal of Obesity & Related Metabolic Disorders (2000), 24(10), 1297-302

BACKGROUND: Obese patients are frequently characterized by insulin resistance and decreased insulin-mediated glycogen synthesis in skeletal muscle. Whether they also have impaired postprandial hepatic ... [more ▼]

BACKGROUND: Obese patients are frequently characterized by insulin resistance and decreased insulin-mediated glycogen synthesis in skeletal muscle. Whether they also have impaired postprandial hepatic glycogen synthesis remains unknown. AIM: To determine whether postprandial hepatic glycogen synthesis is decreased in obese patients compared to lean subjects. METHODS: Lean and obese subjects with impaired glucose tolerance were studied over 4h after ingestion of a glucose load. Hepatic uridine diphosphoglucose kinetics were assessed using 13C-galactose infusion, with monitoring of urinary acetaminophen-glucuronide isotopic enrichment to estimate hepatic glycogen kinetics. RESULTS: Estimated net hepatic glycogen synthesis amounted to 18.6 and 22.6% of the ingested load in lean and obese subjects, respectively. CONCLUSION: Postprandial hepatic glycogen metabolism is not impaired in non-diabetic obese subjects. [less ▲]

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See detailDerived Categories for Functional Analysis
Prosmans, Fabienne ULg

in Publications of the Research Institute for Mathematical Sciences (2000), 36(1), 19-83

We study the homological algebra of the category of locally convex topological vector spaces from the point of view of derived categories.

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See detailField observations on the variability of crude oil impact on indigenous hydrocarbon-degrading bacteria from sub-Antarctic intertidal sediments
Delille, Daniel; Delille, Bruno ULg

in Marine Environmental Research (2000), 49(5), 403-417

Oil pollution of the oceans has been a problem ever since man began to use fossil fuels. Biodegradation by naturally occurring populations of micro-organisms is a major mechanism for the removal of ... [more ▼]

Oil pollution of the oceans has been a problem ever since man began to use fossil fuels. Biodegradation by naturally occurring populations of micro-organisms is a major mechanism for the removal of petroleum from the environment. To examine the effects of crude oil pollution on intertidal bacteria, we repeated the same contamination experiments on nine different sub-Antarctic intertidal beaches using specifically built enclosures (PVC pipe, 15 cm in inner diameter and 30 cm in height). Despite the pristine environmental conditions, significant numbers of indigenous hydrocarbon-degrading bacteria were observed in all the studied beaches. Introduction of oil into these previously oil-free environments resulted in several orders of magnitude of increase in hydrocarbon-degrading micro-organisms within a few days in some of the studied sites but has no obvious effects on two others. The physical environment of the bacterial assemblage seems to play a major role in the biodegradation capacities. After 3 months of contamination, both remaining oil concentrations and biodegradation indexes differ strongly between the different stations. Thus, chemical and biological parameters reveal a strong heterogeneity of biodegradation capacities between the different sites. (C) 2000 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailTherapeutic and chemical developments of cholecystokinin receptor ligands
De Tullio, Pascal ULg; Delarge, J.; Pirotte, Bernard ULg

in Exp. Opin. Invest. Drugs (2000), 9

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See detailStudies in Bacidia sensu lato (lichenized Ascomycetes: Lecanorales). I. The genus Bapalmuia
Kalb, Klaus; Lücking, Robert; Sérusiaux, Emmanuël ULg

in Mycotaxon (2000), 75

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See detailDifferences in associations of familial and nutritional factors with serum lipids between boys and girls: the Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Lambert, A.

in American Journal of Clinical Nutrition (2000), 72(2), 384-8

BACKGROUND: Sex differences in the effects of genetic and environmental factors on circulating lipids have been examined mainly in adults, in whom the influences of sex steroid hormones are well known ... [more ▼]

BACKGROUND: Sex differences in the effects of genetic and environmental factors on circulating lipids have been examined mainly in adults, in whom the influences of sex steroid hormones are well known. OBJECTIVE: Our objective was to determine the effect of sex on genetic and environmental influences on serum lipids in prepubertal boys and girls. DESIGN: Children aged 6-8, 8-10, and 10-12 y (n = 1028) were selected at random in the Belgian province of Luxembourg, a region in Europe with a high prevalence of risk factors for cardiovascular disease and diabetes. Blood glucose and serum cholesterol, triacylglycerol, and insulin concentrations were measured, and anthropometric data and blood pressure were recorded. Familial data were obtained from standardized questionnaires. Nutritional status was obtained from a 3-d record. Participation was 70.3% of the primary cohort. RESULTS: Cholesterol, triacylglycerol, and insulin values were among the highest recorded in studies of children. In girls, cholesterol correlated positively with the energy density of intake of saturated fat (r = 0.13, P = 0.001), cholesterol (r = 0.11, P = 0.006), and protein (r = 0.12, P = 0.007) and negatively with the ratio of polyunsaturated to saturated fat intake (r = -0.14, P = 0.001) and the energy density of carbohydrate intake (r = -0.11, P = 0.019). In boys, no such relations were found. Triacylglycerol was not significantly related to nutritional factors. Consistent, independent relations were found between reported elevated cholesterol concentrations in the parental and grandparental generation and cholesterol (r = 0.101, P = 0.011) and triacylglycerol (r = 0.09, P = 0.03) in boys. No such associations were found in girls. CONCLUSION: Environmental and genetic factors may have different effects on serum cholesterol in girls and boys. [less ▲]

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See detailFailure temperature of a System Comprising a Restrained Column Submitted to Fire
Franssen, Jean-Marc ULg

in Fire Safety Journal (2000), 34

The problem of columns submitted to fire is discussed in the intoduction with an emphasis on the differences between the case of a column acting as a single element or being part of a frame. In the latter ... [more ▼]

The problem of columns submitted to fire is discussed in the intoduction with an emphasis on the differences between the case of a column acting as a single element or being part of a frame. In the latter case, failure of the column does not necessarily lead to the failure of the structure. The basic principles of the arc-length technique are given, first for the way it is applied traditionally at room temperature, then for the way it can be applied to extend a numerical simulation beyond the moment of local failures in case of fire. The technique is then applied to the case of restrained columns and it is shown how it is possible to obtain a safe estimate of the critical temperature of the column leading to the failure of the structure, even if the degree of restraint apllied to the column is unknown. [less ▲]

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See detailTreatment outcome in infant acute lymphoblastic leukemia
Ferster, A; Benoit, Y; Francotte, N et al

in Blood (2000), 95(8), 2729-31

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See detailArticle d'introduction. Colloque du Sart Tilman du 29 avril 2000. Initiatives en matière de management du sport.
Cloes, Marc ULg

in Revue Sport (2000), 172

Le management du sport fait désormais l'objet d'une attention croissante tant de la part des responsables sportifs que de nombreux scientifiques impliqués dans le domaine des activités physiques et ... [more ▼]

Le management du sport fait désormais l'objet d'une attention croissante tant de la part des responsables sportifs que de nombreux scientifiques impliqués dans le domaine des activités physiques et sportives. L'évolution de la société occidentale (individualisme, recherche de profit, concurrence effrénée, effets de mode, etc) concerne directement les organisations sportives, dont les ressources humaines et financières tendent à se raréfier. Les bénévoles fuient les exigences des membres et les responsabilités de plus en plus contraignantes ainsi que le peu de valorisation dont se voit fratifier leur dévouement. Les budgets augmentent et les frais se multiplient tandis que l'aide publique se limite souvent à la portion congrue, incitant les responsables à rechercher la rentabilité. Les sportifs se transforment peu à peu en clients exigeant des services de qualité... [less ▲]

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See detailEosinophilic Bronchopneumopathy in Dogs
Clercx, Cécile ULg; Peeters, Dominique ULg; Snaps, Frédéric ULg et al

in Journal of Veterinary Internal Medicine (2000), 14(3, May-Jun), 282-91

Eosinophilic bronchopneumopathy was diagnosed in 23 young dogs. Clinical signs included cough, gagging, and retching in all dogs, dyspnea in 21 dogs (91%), and nasal discharge in 12 dogs (52%). The most ... [more ▼]

Eosinophilic bronchopneumopathy was diagnosed in 23 young dogs. Clinical signs included cough, gagging, and retching in all dogs, dyspnea in 21 dogs (91%), and nasal discharge in 12 dogs (52%). The most common radiographic findings were a moderate to severe bronchointerstitial pattern (68%, 13 of 19 dogs). Bronchoscopic findings included the presence of abundant yellow-green mucus or mucopurulent material (70%, 16 of 23 dogs) and severe mucosal thickening with an irregular or polypoid appearance (52%, 12 of 23 dogs), with partial airway closure during expiration in 3 dogs (13%). Peripheral blood eosinophilia was noted in 14 of 23 dogs (61%). Inflammatory cells in brush or bronchoalveolar lavage fluid cytologic preparations comprised more than 50% eosinophils in 14 of 23 dogs (61%), and 20-50% eosinophils in 6 dogs (26%). Eosinophilic infiltration of the bronchial mucosa was observed in biopsies from 19 dogs and was graded as mild (37%, 7 dogs), moderate (32%, 6 dogs), or severe (32%, 6 dogs). The mean serum immunoglobulin A concentration was almost double that of a population of 20 healthy dogs of various breeds. Oral glucocorticoids were administered on alternate days with progressive tapering of the dose; the dosage at maintenance varied between 0.1 and 1.0 mg/kg every other day. No relationship was found between the duration of clinical signs and the maintenance dosage or the cytologic and histopathologic grades. [less ▲]

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See detailComment évolue la motivation pour l'école et pour la lecture des enfants entre la 1re et la 3e année primaire
Hindryckx, Geneviève ULg; Schockert, Catherine

in Point sur la Recherche en Education (Le) (2000), 14

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See detailThe branchial basket in Teleost feeding.
Vandewalle, Pierre ULg; Parmentier, Eric ULg; Chardon, Michel ULg

in Cybium (2000), 24(4), 319-342

In teleosts, feeding is effected principally by suction and food is handled by the branchial basket. Preys are carried to the oesophagus by the pharyngeal jaws (PJs). The pharyngobranchial bones ... [more ▼]

In teleosts, feeding is effected principally by suction and food is handled by the branchial basket. Preys are carried to the oesophagus by the pharyngeal jaws (PJs). The pharyngobranchial bones constitute the upper pharyngeal jaws (UPJs) and the 5th ceratobranchial bones, the lower pharyngeal jaws (LPJs). In lower teleosts, these jaws have well-separated spindly parts attached to the neurocranium, pectoral girdle, and hyoid bar; they only transport food and LPJ activity predominates. In acanthopterygians, the PJs become stronger, the left and right ceratobranchials fuse into one LPJ, and the pharyngobranchials join together to form two big UPJs articulating with the neurocranium. In labrids and scarids, the LPJ is also joined to the pectoral girdle. In acanthopterygians, a new retractor dorsalis muscle gives the UPJs the major role in food chewing and transport. Cypriniforms have developed original PJs with strong 5th ceratobranchials opposed to a postero-ventral neurocranial plate. Small-sized preys and food particles are seized by the gill rakers, small skeletal pieces supported by the branchial arches. [less ▲]

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See detailInterplay of anisotropy and competing correlated pinning mechanisms in the angular dependence of the irreversible magnetization of YBa2Cu3O7 crystals
Silhanek, Alejandro ULg; Civale, L.

in Physica C: Superconductivity (2000), 341(Part 2), 1227-1228

We measured the angular dependence of the irreversible magnetization of a YBa2Cu3O7 single crystal with columnar defects (CD) inclined with respect to the c-axis. At temperatures T greater than or equal ... [more ▼]

We measured the angular dependence of the irreversible magnetization of a YBa2Cu3O7 single crystal with columnar defects (CD) inclined with respect to the c-axis. At temperatures T greater than or equal to 40K and high fields we observe a sharp maximum centered at the tracks' direction. At T less than or equal to 20K the behavior is quite different. At high fields a broad bump at the tracks' direction is still visible, but its height is small and it appears only as a perturbation to the angular dependence due to material anisotropy. However, by performing the usual anisotropic rescaling (Blatter et al., Phys. Rev. Lett. 68, 875, 1992) we recover the strong unidirectional effects due to CD's. [less ▲]

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See detailD'un procès à l'autre - pour une esthétique des médias
Servais, Christine ULg

in Recherches en Communication (2000), 13

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See detailWilson Harris Issue
Maes-Jelinek, Hena ULg

in Journal of Caribbean Literatures (2000), 2(1-2-3), 289

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See detailImmunocastration of farm animals
Portetelle, Daniel ULg; Haezebroeck, Valérie; Mortiaux, Frédéric et al

in Bases (2000), 4

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See detailBeta-radiation for coronary in-stent restenosis
Latchem, D-R; Urban, P; Goy, JJ et al

in Catheterization and Cardiovascular Interventions (2000), 51(4), 422-429

To determine the feasibility and safety of an intracoronary beta-radiation device in preventing the recurrence of in-stent restenosis (ISR) after successful angioplasty, we studied 37 patients treated ... [more ▼]

To determine the feasibility and safety of an intracoronary beta-radiation device in preventing the recurrence of in-stent restenosis (ISR) after successful angioplasty, we studied 37 patients treated with beta-radiation (30-mm strontium-90 source) after angioplasty. The mean reference diameter was 2.9 ± 0.5 mm, and 62% of lesions were diffuse, including four total occlusions. Beta-radiation was successfully delivered in 36 of 37 (97%) cases. Over the course of 7.1 ± 4.5 mo follow-up, there were no myocardial infarctions and three deaths: one from preexisting malignancy, one from progressive cardiac failure, and one from sudden cardiac death. Target vessel revascularization (TVR) was performed in seven of 36 (19%) patients. Thirty patients underwent angiography at 6 mo; three (10%) experienced restenosis (diameter stenosis > 50%) at the target site, four (13%) had edge stenoses, and two (7%) had late (> 1 mo) thrombotic occlusions. Beta-radiation for ISR is associated with encouragingly low rates of target lesion restenosis and TVR. Further improvements are needed to solve the limitations of the edge effect and late occlusion. [less ▲]

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See detailLocalization of Nadph-Protochlorophyllide Reductase in Plastids of Barley at Different Greening Stages
Barthelemy, X.; Bouvier, G.; Radunz, A. et al

in Photosynthesis Research (2000), 64(1), 63-76

The localization of protochorophyllide (Pchlide) and of NADPH-protochlorophyllide oxidoreductase (POR, EC 1.6.99.1) within (etio)chloroplasts has been investigated at selected stages of greening of barley ... [more ▼]

The localization of protochorophyllide (Pchlide) and of NADPH-protochlorophyllide oxidoreductase (POR, EC 1.6.99.1) within (etio)chloroplasts has been investigated at selected stages of greening of barley seedlings. Pchlide pigment and POR protein contents were evaluated in different plastid membrane fractions by fluorescence spectroscopy and immunoblot analysis using a monospecific polyclonal antibody raised against the purified enzyme. Fluorescence analysis showed the presence of Pchlide in both the envelope and thylakoid membranes. During greening, the Pchlide content, expressed on a total protein basis, decreased in thylakoid membranes, whereas it increased in the envelope membranes. POR proteins were detected mainly in thylakoid membranes at early greening stages. In contrast, the weak amount of POR proteins was associated more specifically with envelope membranes of mature chloroplasts. Whatever the greening stage, thylakoid-bound Pchlide and POR proteins were more abundant in the thylakoid regions which remained unsolubilized after mild Triton treatment used as standard procedure to prepare PS II particles. This suggests the preferential association of Pchlide and POR to the appressed regions of thylakoids. [less ▲]

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See detailNeoteny and progenesis as two heterochronic processes involved in paedomorphosis in Triturus alpestris (Amphibia: Caudata)
Denoël, Mathieu ULg; Joly, Pierre

in Proceedings of the Royal Society B : Biological Sciences (2000), 267(1451), 1481-1485

Current theories on the evolution of paedomorphosis suppose that several ontogenetic pathways have appeared according to different selective pressures. The aim of this study was to find out whether two ... [more ▼]

Current theories on the evolution of paedomorphosis suppose that several ontogenetic pathways have appeared according to different selective pressures. The aim of this study was to find out whether two distinct processes can lead to paedomorphosis in the Alpine newt, Triturus alpestris. In this respect, we compared age structures of paedomorphic and metamorphic individuals in two newt populations where the two forms lived syntopically. Whereas paedomorphosis resulted in a slower rate of somatic development in one population, it resulted in an acceleration of sexual maturation in the other population. These processes correspond to neoteny and progenesis, respectively. These results suggest that phenotypic plasticity can result from contrasted ontogenetic pathways between two populations of the same species. They give support to models that consider gonadic development as the target of selection under different environmental pressures. [less ▲]

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See detailSimulation of first and second order scattering by rough surfaces with a sound ray formalism
Embrechts, Jean-Jacques ULg

in Journal of Sound & Vibration (2000), 229(1)

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See detailÉric Benoît, Les Poésies de Mallarmé et Mallarmé et le Mystère du « Livre »
Durand, Pascal ULg

in Littératures Classiques (2000), 43(automne), 173-180

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See detailAcute pancreatitis attributed to the use of interferon alfa-2b
Eland, I. A.; Rasch, M. C.; Sturkenboom, M. J. et al

in Gastroenterology (2000), 119(1), 230-233

Two patients experienced episodes of acute pancreatitis shortly after starting treatment with interferon alfa-2b (IFN-alpha) for a chronic hepatitis C infection. The first patient was a 40-year-old man ... [more ▼]

Two patients experienced episodes of acute pancreatitis shortly after starting treatment with interferon alfa-2b (IFN-alpha) for a chronic hepatitis C infection. The first patient was a 40-year-old man who developed acute pancreatitis after 15 weeks of treatment with 3 MU IFN-alpha subcutaneously (SC) 3 times weekly and 1200 mg ribavirin. After disappearance of symptoms and normalization of laboratory values, oral intake of solid foods and IFN-alpha therapy were restarted. Within hours, a relapse of acute pancreatitis occurred. A rechallenge with IFN-alpha 4 days later was followed by a prompt increase in serum lipase level, and IFN-alpha therapy was discontinued. The second patient was a 38-year-old man who developed acute pancreatitis 2 hours after SC administration of 5 MU IFN-alpha. Ultrasound endoscopy showed sludge in the gallbladder. The patient was rechallenged 5 weeks later with 3 MU IFN-alpha SC. Although serum amylase and lipase levels increased after readministration of IFN-alpha, treatment was continued. The patient was readmitted 2 weeks later with severe abdominal pain, and IFN-alpha administration was discontinued. Considering the temporal relationship between the start of IFN-alpha treatment and development of acute pancreatitis, the absence of other clear etiologic factors for acute pancreatitis, disappearance of symptoms after discontinuation of IFN-alpha, and positive reactions to rechallenge, IFN-alpha is the most probable cause for development of acute pancreatitis in these patients. [less ▲]

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See detailIncreased synovial fluid levels of soluble CD23 are associated with an erosive status in rheumatoid arthritis (RA).
Ribbens, Clio ULg; Bonnet, V.; Kaiser, Marie-Joëlle ULg et al

in Clinical & Experimental Immunology (2000), 120(1), 194-199

Synovial fluid (SF) levels of soluble CD23 (sCD23) were determined in 96 patients presenting with an inflammatory knee effusion (73 with RA and 23 with reactive arthritis (ReA) serving as a control ... [more ▼]

Synovial fluid (SF) levels of soluble CD23 (sCD23) were determined in 96 patients presenting with an inflammatory knee effusion (73 with RA and 23 with reactive arthritis (ReA) serving as a control inflammatory non-erosive group) and were correlated with the degree of joint destruction, with local immune parameters (IL-1beta, IL-3, IL-4, IL-6, IL-8, IL-10, IL-12 and sCD25) and with serum markers of inflammation, C-reactive protein and erythrocyte sedimentation rate. RA patients, classified as erosive or not according to Larsen's grade, were separated as follows: (i) 13 patients with non-erosive RA; (ii) 16 RA patients with erosions in hands but not in knees, matched for disease duration with the first group; (iii) 44 RA patients with hand and knee erosions, matched with the second group for rheumatoid factor positivity but of longer disease duration. SF sCD23 levels were significantly increased in both erosive RA groups compared with non-erosive diseases, whether RA or ReA (P < 0.05), whose SF levels were not different. SF IL-10 showed a similar profile to that of SF sCD23 and was the only other parameter characteristic of erosive RA, but no direct correlation was found between the two. SF sCD23 was significantly correlated with IL-12 (r = 0.65, P = 0.0001) and sCD25 (r = 0.39, P = 0.0019) exclusively in the two erosive RA populations. In conclusion, these data showing that increased levels of sCD23 are not only found in the SF of erosive joints but also in knee SF of patients with erosive RA but without knee x-ray-diagnosed erosions suggest that this parameter might be of predictive value for joint destruction. Longitudinal studies are however needed to confirm its potential clinical interest. [less ▲]

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See detailComment utiliser l'hypnose en anesthésie
Faymonville, Marie ULg; Joris, Jean ULg; Lamy, Maurice ULg

in Praticien en Anesthésie Réanimation (Le) (2000), 4(6), 345-348

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See detailHigh-energy forward scattering and the pomeron: Simple pole versus unitarized models
Cudell, Jean-René ULg; Ezhela, V.; Kang, K. et al

in Physical Review. D : Particles and Fields (2000), 61

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See detailSignificance of random illite-vermiculite mixed layers in Pleistocene sediments of the northwestern Atlantic Ocean
Vanderaveroet, P.; Bout-Roumazeilles, V.; Fagel, Nathalie ULg et al

in Clay Minerals (2000), 35(4), 679-691

The clay mineralogy of Pleistocene sediments of eleven sediment cores at three ODP sites from 30 degrees N to 60 degrees N northwestern Atlantic Ocean has been investigated. The sediments are ... [more ▼]

The clay mineralogy of Pleistocene sediments of eleven sediment cores at three ODP sites from 30 degrees N to 60 degrees N northwestern Atlantic Ocean has been investigated. The sediments are characterized by the presence of random illite-vermiculite mixed layers (I-V) (up to 32% of the clay mineral assemblage). The I-V clays are much more abundant during interglacial periods than during glacial ones. They are attributed to detrital supply through erosion of high-latitude continental areas from which they are derived mainly from chemical weathering of micaceous phyllosilicates. Their spatial distribution and the specific conditions for their formation through weathering suggest that I-V mixed layers are mainly derived from the Canadian Shield. They were transported From their source to marine deposition areas by rivers, deep water masses or nepheloid layers. Due to the specific conditions required For the Formation of I-V, its occurrence and abundance are used as a palaeoclimate and palaeocirculation proxy for northwestern Atlantic Pleistocene sediment. [less ▲]

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See detailEffective treatment of Jo-1-associated polymyositis with T-cell-depleted autologous peripheral blood stem cell transplantation.
Baron, Frédéric ULg; Ribbens, Clio ULg; Kaye, O. et al

in British Journal of Haematology (2000), 110(2), 339-342

A patient with Jo-1 antibody-associated polymyositis (Jo-1 PM) had a Karnofsky score of 40% and severe muscle, liver and lung damage that was refractory to standard therapy. The female patient received an ... [more ▼]

A patient with Jo-1 antibody-associated polymyositis (Jo-1 PM) had a Karnofsky score of 40% and severe muscle, liver and lung damage that was refractory to standard therapy. The female patient received an autologous T-cell-depleted haematopoietic stem cell transplant (HSCT) after myeloablative conditioning. The transplant procedure was complicated by severe adult respiratory distress syndrome (ARDS) and adenovirus-associated haemorrhagic cystitis as well as cytomegalovirus (CMV) reactivation. The patient's creatinine phosphokinase (CPK) and alanine transaminase (ALT) values were normal on day 21. The patient's strength has improved remarkably and her dyspnoea is subjectively improved. At 15 months after the transplant, the patient was well with a Karnofsky score of 80% and had been off any therapy, including steroids, for 14 months. [less ▲]

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See detailValue of technegas for ventilation imaging in calf
Votion, Dominique ULg; Coghe, J.; Lekeux, Pierre ULg

in European Journal of Nuclear Medicine (2000), 27

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See detailLa libre circulation des personnes dans l'Union européenne (1er janvier - 31 décembre 1999)
Carlier, Jean-Yves ULg

in Journal de Droit Européen [=JDE] (2000)

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See detailGuerres au Congo (1996-1999), acteurs et scénarios
Kabamba, Bob ULg

in cahiers du CEDAF (2000)

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See detailAlternative area-perimeter ratios for measurement of 2-D shape compactness of habitats.
Bogaert, Jan ULg; Rousseau, R; Van Hecke, P et al

in Applied Mathematics and Computation (2000), 111(1), 71-85

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See detailEvaluation thérapeutique précoce par tomographie à émission de positons
Jerusalem, Guy ULg; Beguin, Yves ULg; Fassotte, Marie-France ULg et al

in Médecine et Hygiène (2000), 58

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See detailAuditory processing in the vegetative state.
Laureys, Steven ULg; Faymonville, Marie ULg; Degueldre, Christian ULg et al

in Brain : A Journal of Neurology (2000), 123 ( Pt 8)

H(2)(15)O-PET was used to investigate changes in regional cerebral blood flow in response to auditory stimulation in patients in the vegetative state. Five patients in a vegetative state of hypoxic origin ... [more ▼]

H(2)(15)O-PET was used to investigate changes in regional cerebral blood flow in response to auditory stimulation in patients in the vegetative state. Five patients in a vegetative state of hypoxic origin were compared with 18 age-matched controls. In addition, the cerebral metabolism of these patients and 53 age-matched controls was studied using [(18)F]fluorodeoxyglucose. In control subjects, auditory click stimuli activated bilateral auditory cortices [Brodmann areas (BA) 41 and 42] and the contralateral auditory association cortices (BA 22). In the patients, although resting metabolism was decreased to 61% of normal values, bilateral auditory areas 41 and 42 showed activation as seen in the controls, but the temporoparietal junction cortex (BA 22) failed to be activated. Moreover, the auditory association cortex was functionally disconnected from the posterior parietal association area (BA 40), the anterior cingulate cortex (BA 24) and the hippocampus, as revealed by psychophysiological interaction analysis. Thus, despite altered resting metabolism, the auditory primary cortices were still activated during external stimulation, whereas hierarchically higher-order multi- modal association areas were not. Such a cascade of functional disconnections along the auditory cortical pathways, from the primary auditory areas to multimodal and limbic areas, suggests that the residual cortical processing observed in the vegetative state cannot lead to the integrative processes that are thought to be necessary for the attainment of the normal level of awareness. [less ▲]

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See detailIdentification and characterization of in vivo attenuated mutants of Brucella melitensis.
Lestrate, P.; Delrue, R. M.; DANESE, Isabelle ULg et al

in Molecular Microbiology (2000), 38(3), 543-51

Brucella melitensis 16M is a Gram-negative alpha2-proteobacterium responsible for abortion in goats and for Malta fever in humans. This facultative intracellular pathogen invades into and survives within ... [more ▼]

Brucella melitensis 16M is a Gram-negative alpha2-proteobacterium responsible for abortion in goats and for Malta fever in humans. This facultative intracellular pathogen invades into and survives within both professional and non-professional phagocytes. Signature-tagged mutagenesis (STM) was used to identify genes required for the in vivo pathogenesis of Brucella. A library of transposon mutants was screened in a murine infection model. Out of 672 mutants screened, 20 were not recovered after a 5 day passage in BALB/c mice. The attenuation of 18 mutants was confirmed using an in vivo competition assay against the wild-type strain. The 18 mutants were characterized further for their ability to replicate in murine macrophages and in HeLa cells. The sequences disrupted by the transposon in the mutants have homology to genes coding for proteins of different functional classes: transport, amino acid and DNA metabolism, transcriptional regulation, peptidoglycan synthesis, a chaperone-like protein and proteins of unknown function. The mutants selected in this study provide new insights into the molecular basis of Brucella virulence. [less ▲]

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See detailDo estrogens effectively prevent osteoporosis-related fractures?
Reginster, Jean-Yves ULg; Bruyère, Olivier ULg; Audan, M. et al

in Calcified Tissue International (2000), 67

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