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See detailProduction et utilisation du colza en Belgique.
Cartrysse, C.; Cors, F.; Wathelet, Jean-Paul ULg

in GCIRC Bulletin (1991)

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See detailConformational analysis of beta and gamma lactam antibiotics
Lamotte, Josette ULg; Dive, Georges ULg; Ghuysen, Jean-Marie ULg

in European Journal of Medicinal Chemistry (1991), 26(1), 43-50

Geometry optimization, superimposition searches and conformational analysis carried on several lactam antibiotics show that reactivity with the active-site serine penicillin-binding proteins is related to ... [more ▼]

Geometry optimization, superimposition searches and conformational analysis carried on several lactam antibiotics show that reactivity with the active-site serine penicillin-binding proteins is related to a particular spatial disposition of 2 flanking functional groups - namely a C = O or C-OH on 1 side and a carboxylate on the other - with respect to the central scissile amide bond. Such a binding entity is found in one of the most stable conformers of the tripeptide diacetyl-L-Lys-D-Ala-D-Ala conferring substrate activity, and in benzylpenicillin, cephapyrin, thienamycin, gamma-lactam, the 6-spiro-epoxypenicillin S and in one epimer of lactivicin, conferring inactivating potency. This binding entity generates a particular electronic distribution and the fact that it is conserved in compounds belonging to very different chemical families strongly suggests that it is an important feature required for enzyme recognition. [less ▲]

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See detailBiostatistical studies on western European Dactylorhiza (Orchidaceae)-the D. maculata group
Dufrêne, Marc ULg; Gathoye, J.-L.; Tyteca, D.

in Plant Systematics & Evolution (1991), 175(1-2), 55-72

Multivariate analysis tools are exploited on a data set composed of quantitative characteristics collected on 35 populations of plants of the Dactylorhiza maculata (L.)Soó group from Western-Europe. These ... [more ▼]

Multivariate analysis tools are exploited on a data set composed of quantitative characteristics collected on 35 populations of plants of the Dactylorhiza maculata (L.)Soó group from Western-Europe. These samples lead to four well-defined clusters; this, together with qualitative, cytological and ecological arguments, allows for the recognition of four specific entities:D. maculata s.str., D. fuchsii (Druce)Soó, D. saccifera (Brongn.)Soó and D. caramulensis (Vermeulen)Tyteca. It is concluded that the floral characters play an essential role in the taxonomical distinction. It also appears that the set of characters measured, as well as the methods exploited, are especially well-suited and valuable tools for the morphological study of the genus Dactylorhiza. © 1991 Springer-Verlag. [less ▲]

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See detailApproche physique des phénomènes hydrodynamiques
Marchal, Jean ULg

in Revue de l'AIRH (1991)

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See detailDes nouveaux supports électroniques. Pour qui ? pour quoi ?
Denooz, Joseph ULg

in Revue. Informatique et Statistique dans les Sciences Humaines (1991), 27

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See detailThe lack of relationship between DST nonsuppression in the dexamethasone suppression test and EEG abnormalities.
Pitchot, William ULg; Hansenne, Michel ULg; Ansseau, Marc ULg

in European Archives of Psychiatry & Clinical Neuroscience (1991), 241(3), 193-4

As a recent study suggested a relationship between cortisol escape following dexamethasone suppression test (DST) and electroencephalogram (EEG) abnormalities, we tried to replicate these findings in 52 ... [more ▼]

As a recent study suggested a relationship between cortisol escape following dexamethasone suppression test (DST) and electroencephalogram (EEG) abnormalities, we tried to replicate these findings in 52 major depressive inpatients. A total of 23 patients exhibited DST nonsuppression (44%) and 18 patients had EEG abnormalities (35%). No relationship existed between DST and EEG results. [less ▲]

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See detailEros et Thanatos
Duchesne, Jean-Patrick ULg

in Art&fact (1991), 10

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See detailJulian Key
Duchesne, Jean-Patrick ULg

in Sint-Lukasgalerij (1991), 2

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See detailIntroduction à l'arithmétique des algèbres de quaternions
Pays, Isabelle ULg; Tignol, Jean-Pierre

in Note di Matematica e Fisica, Cerfim, Locarno (5) (1991)

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See detailLa maison de repos, une entreprise de services
Jurion, Bernard ULg

in Association des Directeurs de Maisons de Repos de la Communauté Française (1991), 8

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See detailA Monoclonal Elisa for Bovine Viral Diarrhoea Pestivirus Antigen Detection in Persistently Infected Cattle
Mignon, Bernard ULg; Dubuisson, J.; Baranowski, E. et al

in Journal of Virological Methods (1991), 35(2), 177-188

Detection of cattle persistently infected with bovine viral diarrhoea virus (BVDV) is crucial to controlling mucosal disease. A sandwich enzyme-linked immunosorbent assay (ELISA) using monoclonal ... [more ▼]

Detection of cattle persistently infected with bovine viral diarrhoea virus (BVDV) is crucial to controlling mucosal disease. A sandwich enzyme-linked immunosorbent assay (ELISA) using monoclonal antibodies raised against the 48-kDa glycoprotein and the 120/80-kDa protein was developed for detecting antigens in leucocytes of 3 persistently BVDV-infected calves. The test is simple, sensitive and rapid. Moreover the same ELISA was able to recognise Belgian field isolates of BVDV. These results show that the test can be applied in the field. [less ▲]

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See detailThe 1991 EGAS Conference in Torun
Biémont, Emile ULg; Werth, G.

in Europhysics News (1991), 22

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See detailL'examen cytogénétique en onco-hématologie : son importance dans la stratégie thérapeutique
Collignon, J.; Laurent, C.; Rombout, S. et al

in Médecine et Hygiène (1991), 49

The findings that chromosomal aberrations are specifically associated with a considerable number of tumors and particularly leukemia, have lead the cytogenetic studies to be considered particularly ... [more ▼]

The findings that chromosomal aberrations are specifically associated with a considerable number of tumors and particularly leukemia, have lead the cytogenetic studies to be considered particularly contributive in haematological practices. Since the discovery of th Philadelphia chromosome linked with the chronic myeloid leukemia, technological improvements have allowed detection of others chromosomes specifically associated with some types or subtypes of leukemia, lymphomas and solid tumors. Today, cytogenetics is considered as a useful tool not only for diagnostic but also for prognosis and therapeutic. During the follow-up, it may assess not only complete remission, success of bone marrow transplantation but also relapse. Bone marrow cytogenetic studies are being now essential at diagnosis and during follow-up of patients with hematological proliferative tumors. Well done, cytogenetics studies may be of importance for the therapeutic decision. [less ▲]

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See detailLove in a Post-Cultural Ditch: Janet Frame
Delrez, Marc ULg

in Kunapipi : Journal of Postcolonial Writing (1991), XIII(3), 108-116

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See detailAllergic cross-reaction of teicoplanin and vancomycin
Grek, V.; Andrien, F.; Collignon, J. et al

in Journal of Antimicrobial Chemotherapy (1991), 28

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See detailUne plaquette filigranée du XIIIe siècle découverte à Stavelot. Identification et conservation
Van den Bossche, Benoît ULg; Dewanckel, Gilberte; Paquet, Pierre ULg et al

in Bulletin de l'Institut Royal du Patrimoine Artistique (1991), 23

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See detailCalcul de la propagation d'une onde de rupture de barrage
Pirotton, Michel ULg

in Tribune de l'Eau (La) (1991), 44(551), 23-31

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See detailChoice of sedation according to ventilatory mode
Lamy, Maurice ULg; Damas, Pierre ULg; Joris, Jean ULg

in Journal of drug development (1991), 4(Suppl 3), 77-81

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See detailComparaison de techniques de calcul des équations de calibrage en analyse des protéines du blé par spectrophotométrie de réflexion dans le proche infrarouge
Dagnelie, P.; Dardenne, P.; Palm, Rodolphe ULg et al

in Bulletin des Recherches Agronomiques de Gembloux (1991), 26(3), 323-336

Dans le cas des protéines du blé tendre, on étudie l'incidence, sur la qualité des équations de calibrage, des transformations appliquées aux spectres bruts (lissage par calcul des moyennes mobiles ... [more ▼]

Dans le cas des protéines du blé tendre, on étudie l'incidence, sur la qualité des équations de calibrage, des transformations appliquées aux spectres bruts (lissage par calcul des moyennes mobiles, dérivées premières, dérivées secondes et calcul des coefficients de FOURIER) et des procédures de réduction préliminaire du nombre de longueurs d'onde prises en considération (choix systématique et choix basé sur la corrélation entre réponses aux longueurs d'onde voisines). [less ▲]

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See detailPneumonie vermineuse caprine à Mulerius capillaris : étude des paramètres de la fonction pulmonaire
Bakima, M.; Arendt, J.; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1991), 131

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See detailLa recherche en Brucellose entreprise par le CEB (1e partie)
Limet, J.; Oanh Vo, T. K.; Saegerman, Claude ULg et al

in Les élevages belges (1991)

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See detailMetal Forming Analysis via Eulerian-Lagrangian FEM with Adaptive Mesh
Hogge, Michel ULg; Ponthot, Jean-Philippe ULg

in Latin American Research Review (1991), 21

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See detailChest wall motion during epidural anesthesia in dogs.
Warner, David O; Brichant, Jean-François ULg; Ritman, Erik L et al

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1991), 70(2), 539-47

To determine the relative contribution of rib cage and abdominal muscles to expiratory muscle activity during quiet breathing, we used lumbar epidural anesthesia in six pentobarbital sodium-anesthetized ... [more ▼]

To determine the relative contribution of rib cage and abdominal muscles to expiratory muscle activity during quiet breathing, we used lumbar epidural anesthesia in six pentobarbital sodium-anesthetized dogs lying supine to paralyze the abdominal muscles while leaving rib cage muscle motor function substantially intact. A high-speed X-ray scanner (Dynamic Spatial Reconstructor) provided three-dimensional images of the thorax. The contribution of expiratory muscle activity to tidal breathing was assessed by a comparison of chest wall configuration during relaxed apnea with that at end expiration. We found that expiratory muscle activity was responsible for approximately half of the changes in thoracic volume during inspiration. Paralysis of the abdominal muscles had little effect on the pattern of breathing, including the contribution of expiratory muscle activity to tidal breathing, in most dogs. We conclude that, although there is consistent phasic expiratory electrical activity in both the rib cage and the abdominal muscles of pentobarbital-anesthetized dogs lying supine, the muscles of the rib cage are mechanically the most important expiratory muscles during quiet breathing. [less ▲]

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See detailPour un roman sans manifeste
Demoulin, Laurent ULg

in Ecritures (1991), 1

Description des nouvelles tendances du roman écrit en français.

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See detailRésection ureteroscopique du polype fibreux de l'uretère
Nicolas, Hubert; Vandeberg, Colette ULg; Bonnet, Pierre ULg et al

in Acta Urologica Belgica (1991), 59(3), 119-30

From a new case of fibroepithelial polyp in a 41 year old woman, we reviewed literature on this rare and benign pathology, for which differential diagnosis with malignant tumor is most often obtained ... [more ▼]

From a new case of fibroepithelial polyp in a 41 year old woman, we reviewed literature on this rare and benign pathology, for which differential diagnosis with malignant tumor is most often obtained surgically. We emphasize both diagnostic and therapeutic advantages of endoscopic approach of this lesion. [less ▲]

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See detailDermal Dendrocytes and Photochemotherapy
Pierard, Gérald ULg; Nikkels, Arjen ULg; Arrese Estrada, Jorge ULg et al

in Virchows Archiv. A : Pathological Anatomy and Histopathology (1991), 418(4), 311-314

We studied the fate of dermal dendrocytes in patients treated with psoralens and ultraviolet light by combining immunohistochemistry and computerized image analysis. Factor-XIIIa-positive dermal ... [more ▼]

We studied the fate of dermal dendrocytes in patients treated with psoralens and ultraviolet light by combining immunohistochemistry and computerized image analysis. Factor-XIIIa-positive dermal dendrocytes were found to be altered in these patients. When compared with controls, dermal dendrocytes were often increased in number and had an uneven size and tissue distribution. Their cytoplasm was occasionally fragmented. These changes were more pronounced when early photosclerosis was present. The alterations described probably reflect vascular changes, and may be responsible for immunomodulating actions and disorder of the connective tissue structure induced by ultraviolet light. [less ▲]

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See detailManagement of small woods in Belgium.
Rondeux, Jacques ULg

in Quarterly Journal of Forestry (1991), 85(1), 37-42

In Belgium, forest occupies 20 per cent of the total land area. Private forests account for about 52 per cent; they are generally small (averaging about three ha) and their owners are not accustomed to ... [more ▼]

In Belgium, forest occupies 20 per cent of the total land area. Private forests account for about 52 per cent; they are generally small (averaging about three ha) and their owners are not accustomed to basing their decisions on a management plan. However, some attempts to develop co-operation through forestry associations exist and the regional authorities tend to encourage them. Whatever the details of any possible future legislation may be, the principal aim must be the development and introduction of an extremely simple form of management plan (the so-called 'plan simple de gestion') in exchange for assistance to the private owner. [less ▲]

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See detailEchantillonnage à probabilité de sélection proportionnelle à la prédiction et inventaires forestiers.
Hebert, Jacques ULg; Rondeux, Jacques ULg

in Annales de Gembloux (1991), 97(3), 221-231

The so-called 3 P sampling system (sampling with Probability Proportional to Prediction) is a variation of list sampling that does not require a list of population elements prior to the inventory. Every ... [more ▼]

The so-called 3 P sampling system (sampling with Probability Proportional to Prediction) is a variation of list sampling that does not require a list of population elements prior to the inventory. Every tree in a timber sale has to be visited and one needs an estimate of the total volume. In order to correct the total estimated volume, a small number of sample trees are selected according to a unequal-probability selection rule. The predicted tree volume is paired with a random number. Trees with predicted values larger than or equal to the random number are precisely measured. The average ratio of the measured volume to the estimated volume in the sample is used to adjust the total estimated volume. Such a system of inventory is often designed where a highly precise estimate of the volume or value of standing trees is required. [less ▲]

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See detailImprovement of insulin-induced glucose disposal in obese patients with NIDDM after 1-wk treatment with d-fenfluramine.
Scheen, André ULg; Paolisso, G.; Salvatore, T. et al

in Diabetes Care (1991), 14(4), 325-32

OBJECTIVE: To study the short-term effects of the serotoninergic anorectic drug d-fenfluramine on insulin-induced glucose disposal. RESEARCH DESIGN AND METHODS: A randomized double-blind placebo ... [more ▼]

OBJECTIVE: To study the short-term effects of the serotoninergic anorectic drug d-fenfluramine on insulin-induced glucose disposal. RESEARCH DESIGN AND METHODS: A randomized double-blind placebo-controlled crossover trial with 1-wk treatment periods (2 x 15 mg/day d-fenfluramine) was conducted. Twenty obese subjects, 10 with normal oral glucose tolerance and 10 with non-insulin-dependent diabetes mellitus (NIDDM), were all treated with a weight-maintaining diet. Euglycemic-hyperinsulinemic glucose clamps with measurement of glucose kinetics with D-[3-3H]glucose were performed at either two (patients without NIDDM, 0.05 and 0.10 U.kg-1.h-1) or three (patients with NIDDM, 0.05, 0.10, and 0.50 U.kg-1.h-1) insulin delivery rates. RESULTS: In the nondiabetic subjects, no significant changes in any metabolic or hormonal parameter were measured in the basal state or during the clamp despite a slight reduction in body weight (-1.2 +/- 0.5 kg, P less than 0.05). In the diabetic patients, no significant changes in body weight or basal plasma insulin levels were observed, but fasting blood glucose levels (8.0 +/- 0.8 vs. 9.4 +/- 1.1 mM, P less than 0.005) and plasma free fatty acid concentrations (1150 +/- 227 vs. 1640 +/- 184 microM, P less than 0.05) were significantly reduced after d-fenfluramine compared with placebo. During the clamp, insulin metabolic clearance rate (MCR) was similar after both placebo and d-fenfluramine; endogenous (hepatic) glucose production was similarly and almost completely suppressed, whereas glucose disposal was remarkably enhanced after d-fenfluramine (average increase of glucose MCR 35 +/- 12%, P less than 0.02). CONCLUSIONS: Whatever the mechanism(s) involved, a 1-wk treatment with d-fenfluramine induces better blood glucose control and improves insulin sensitivity in obese patients with NIDDM independent of significant weight reduction; this last effect is not present in obese subjects with normal oral glucose tolerance. [less ▲]

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See detailImpact de la pollution atmosphérique sur le système respiratoire. I : l’ammoniac
Gustin, Pascal ULg; Urbain, B.; Ansay, M. et al

in Annales de Médecine Vétérinaire (1991), 135

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See detailModélisation moléculaire de l'usambarensine, de la tubulosine et de l'émétine, alcaloïdes cytotoxiques et antiamibiens
Quetin-Leclercq, J.; Dupont, Léon ULg; Wright, C. W. et al

in Journal de Pharmacie de Belgique (1991), 46(2, Mar-Apr), 85-92

The analyses of the different possible conformations of usambarensine, tubulosine and emetine, which possess interesting cytotoxic and amoebicide properties showed us that they cannot take the planar ... [more ▼]

The analyses of the different possible conformations of usambarensine, tubulosine and emetine, which possess interesting cytotoxic and amoebicide properties showed us that they cannot take the planar conformation proposed to explain the activity of this type of molecules on protein synthesis. Nevertheless, a common (non planar) conformation exists where the angles between the two plans containing the aromatic rings are nearly the same for the three compounds. This fact could confirm the hypothesis of a common receptor which would be slightly different in amoebae because of its higher sensitivity to usambarensine. [less ▲]

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See detailSEARCH FOR PARVALBUMIN IN CARDIAC-MUSCLE OF NORMAL AND HEMOGLOBIN-MYOGLOBIN FREE ANTARCTIC FISH
Laforet, C.; Feller, Georges ULg; Gerday, Colette ULg

in Journal of Muscle Research and Cell Motility (1991), 12(1), 115-116

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See detailPit-1 binding sequences permit calcium regulation of human prolactin gene expression
Hoggard, Nigel; Davis, Julian R E; Berwaer, Monique et al

in Molecular Endocrinology (1991), 5(11), 1748-54

This study examines the regulation of the human PRL (hPRL) gene promoter by intracellular calcium. Deletants of the 5'-flanking region of the hPRL gene and constructs consisting of the thymidine kinase ... [more ▼]

This study examines the regulation of the human PRL (hPRL) gene promoter by intracellular calcium. Deletants of the 5'-flanking region of the hPRL gene and constructs consisting of the thymidine kinase promoter linked to the first or second proximal Pit-1 binding site were fused to the bacterial chloramphenicol acetyl transferase (CAT) reporter gene. With the complete 5-kilobase pair (kbp) hPRL promoter sequence the calcium channel agonist Bay K8644 induced a significant 2-fold increase in CAT reporter gene expression and the antagonist verapamil a 4.5-fold reduction, using GH3 cells cultured in physiological levels of calcium. The transcriptional response to calcium influx was similar with a series of 5'-deleted hPRL-CAT constructs including those that comprised the proximal (up to 740 bp) or distal (-1300- to -1700-bp) sequences alone. When treating cells cultured in low calcium conditions the induction with the hPRL promoter increased to 5-fold on the addition of exogenous calcium and Bay K8644. The pituitary-specific expression of the hPRL gene is conferred by the interaction of the pituitary-specific factor Pit-1 with several binding sites located in the 5'-flanking DNA, of which three are located in the proximal region. This suggested that Pit-1 binding sites may be involved in the calcium response.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailNew hypothesis on the conformation of the PAF receptor from studies on the geometry of selected platelet-activating-factor antagonists
Batt, Jean-Pierre; Lamouri, Aazdine; Tavet, Fabrice et al

in Journal of Lipid Mediators (1991), 4(3), 343-346

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See detailPhotosystem II assembly in 2-day-old bean leaves during the first 16 hrs. of greening
Schoefs, Benoît; Franck, Fabrice ULg

in Comptes Rendus de l'Académie des Sciences. Série III, Sciences de la Vie (1991), 313(10), 441-445

We have studied the assembly of the photosynthetic apparatus during the greening of 2-day-old bean leaves in continuous white light by using fluorimetric methods. We have recorded 77 and 298 K ... [more ▼]

We have studied the assembly of the photosynthetic apparatus during the greening of 2-day-old bean leaves in continuous white light by using fluorimetric methods. We have recorded 77 and 298 K fluorescence kinetics at 690 nm in order to detect electron flow through the photosystem II reaction centre (RC(II)) at increasing greening periods. In those experiments, the 77 K fluorescence spectra were also considered. Charge separation is detected 1 hr. after the onset of the illumination. Room temperature fluorescence variation showing the << O-I-P >> phases are detected after 4 hrs. of illumination. Typical fluorescence bands at 688, 697 and 735 nm appear after 14 hrs. of illumination. [less ▲]

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See detailExcision of imidazole ring-opened N7-hydroxyethylguanine from chloroethylnitrosourea-treated DNA by Escherichia coli formamidopyrimidine-DNA glycolsylase
Laval, J.; Lopes, F.; Madelmont, J. et al

in IARC Scientific Publications (1991), 105

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See detailSurveillance des variations de la nappe d'eau superficielle en Fagnes de Duret et du Setay
Erpicum, Michel ULg; Streel, Maurice ULg; Groulard, J. M. et al

in Hautes Fagnes (1991), 203

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See detailLa biologie des infections par morbillivirus
Pastoret, Paul-Pierre ULg; Van Bressem, M. F.; Diallo, A. et al

in Annales de Médecine Vétérinaire (1991), 135

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See detailConserved KRAB protein domain identified upstream from the zinc finger region of Kox 8
Thiesen, H. J.; Bellefroid, E.; Revelant, O. et al

in Nucleic Acids Research (1991), 19(14), 3996

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See detailLes plantes emsiennes de Marchin (bord nord du Synclinorium de Dinant, Belgique). II. Forgesia curvata gen. et sp. nov.
Gerrienne, Philippe ULg

in Comptes Rendus de l'Académie des Sciences. Série II. Mécanique, Physique, Chimie, Sciences de l'Univers, Sciences de la Terre (1991), 313

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See detailTarifs de cubage peuplement pour le douglas Pseudotsuga menziesii (Mirb.) Franco en moyenne et haute Belgique
Rondeux, Jacques ULg; Laurent, Christian; Lejeune, Philippe ULg

in Revue Forestière Française (1991), XLIII(6), 507-513

L'estimation rapide du volume des peuplements de nos principales essences forestières peut être réalisée au moyen de tarifs de cubage de peuplements. Nous avons mis à profit de grand nombre de données ... [more ▼]

L'estimation rapide du volume des peuplements de nos principales essences forestières peut être réalisée au moyen de tarifs de cubage de peuplements. Nous avons mis à profit de grand nombre de données dendrométrique récoltées dans le cadre d'une étude consacrée à la sylviculture et à la production du Douglas, pour établir des tarifs adaptés à la détermination du volume des peuplements de ce résineux en pleine expansion et qui couvre aujourd'hui près de 11 000 hectares en Moyenne et Haute Belgique. Nous présenterons d'abord les caractéristiques du matériel expérimental ainsi que la technique de construction des tarifs et nous fournirons les résultats obtenus pour le volume bois fort tige ainsi que ceux relatifs à différentes découpes, et, nous envisagerons enfin l'utilisation pratique de ces tarifs et rappellerons leur intérêt en matière de gestion forestière. [less ▲]

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See detailCharacterization of Monoclonal Antibodies to Bovine Viral Diarrhoea Virus: Evidence of a Neutralizing Activity against Gp48 in the Presence of Goat Anti-Mouse Immunoglobulin Serum
Boulanger, D.; Waxweiler, Sophie; Karelle, L. et al

in Journal of General Virology (1991), 72(5), 1195-1198

Twenty-one monoclonal antibodies (MAbs) directed against the NY-1 and the Osloss-c strains of bovine viral diarrhoea virus were produced and characterized by indirect immunofluorescence assay ... [more ▼]

Twenty-one monoclonal antibodies (MAbs) directed against the NY-1 and the Osloss-c strains of bovine viral diarrhoea virus were produced and characterized by indirect immunofluorescence assay, radioimmunoprecipitation and neutralization tests. Fourteen MAbs directed against the NY-1 strain recognized the gp48 and showed a weak neutralizing activity in the presence of goat anti-mouse immunoglobulin serum. [less ▲]

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See detailConvergence variationnelle et opérateurs maximaux monotones d'un espace de Hilbert réel
Tossings, Patricia ULg

in Bulletin de la Société Royale des Sciences de Liège (1991), 60(2), 103-132

Following an idea due to H. Attouch and R.J.B. Wets in the context of variational convergence theory and convex optimization, we introduce, on the set of maximal monotone operators on a real Hilbert space ... [more ▼]

Following an idea due to H. Attouch and R.J.B. Wets in the context of variational convergence theory and convex optimization, we introduce, on the set of maximal monotone operators on a real Hilbert space, a parametric semi-distance, which induces a stronger notion of convergence than the graph convergence. This metric is fundamental in the theoretical study of algorithms for searching a zero of a maximal monotone operator on a real Hilbert space. [less ▲]

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See detailOstéite sternale et médiastinite après chirurgie de pontage aorto-coronaire
DETROZ, B.; Defraigne, Jean-Olivier ULg; Limet, Raymond ULg

in Annales de Chirurgie (1991), 45(2), 128-35

Between 1980 and 1987, 31 cases of osteitis (n = 9) and/or mediastinitis (n = 22) were observed after 2,801 consecutive aorto-coronary bypasses (1.1%). Three types of treatment were used: 1) sternal ... [more ▼]

Between 1980 and 1987, 31 cases of osteitis (n = 9) and/or mediastinitis (n = 22) were observed after 2,801 consecutive aorto-coronary bypasses (1.1%). Three types of treatment were used: 1) sternal debridement with osteosynthesis and continuous mediastinal irrigation (n = 25); 2) sternal and mediastinal debridement with open drainage without osteosynthesis (n = 2); 3) incision and debridement of sternal abscesses (n = 4). The overall mortality was 26% (8/31), i.e. 11% (1/9) for isolated osteitis and 32% (7/22) for mediastinitis. Four factors were statistically associated with infection: reoperation for hemorrhage (19.4%, p less than 0.001); preoperative diabetes (25%, p less than 0.001), postoperative low cardiac output (55%, p less than 0.001), postoperative respiratory insufficiency (45%, p less than 0.001). [less ▲]

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See detailcompte rendu de G. Ballaira, Prisciano e i suoi amici, Turin, 1989
Rochette, Bruno ULg

in Scriptorium. Bulletin codicologique (1991)

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See detailHalothane, enflurane, and isoflurane depress the peripheral vagal motor pathway in isolated canine tracheal smooth muscle.
Brichant, Jean-François ULg; Gunst, Susan J; Warner, David O et al

in Anesthesiology (1991), 74(2), 325-32

Volatile anesthetics are potent bronchodilators, but the site of action for the dilation is unclear. To determine the site of action of halothane, enflurane, and isoflurane on the peripheral vagal motor ... [more ▼]

Volatile anesthetics are potent bronchodilators, but the site of action for the dilation is unclear. To determine the site of action of halothane, enflurane, and isoflurane on the peripheral vagal motor pathway, isolated strips of canine trachealis muscle were stimulated before and during exposure to halothane at 0.3, 1.0, 1.7, or 2.4 MAC, enflurane at 1 MAC, or isoflurane at 1 MAC. The sites and methods of stimulation were: 1) postsynaptic nicotinic cholinergic receptors in the intramural parasympathetic ganglia, with 1,1-dimethyl-4-phenyl-piperazinium iodide (DMPP); 2) postganglionic cholinergic nerve fibers, with electrical field stimulation (EFS); and 3) muscarinic cholinergic receptors of the smooth muscle, with acetylcholine (ACh). The concentration-response curve to DMPP was significantly shifted to the right by 0.3 MAC halothane, whereas 0.3 MAC halothane had no significant effect on the concentration-response curves to ACh and EFS. At concentrations greater than 1 MAC of halothane, enflurane, or isoflurane, concentration-response curves to all three stimuli were shifted significantly to the right; i.e., the contractile responses to ACh, EFS, and DMPP were reduced. At all concentrations of halothane the force of contraction was significantly more reduced during stimulation with DMPP than during stimulation with ACh, and at halothane concentrations greater than or equal to 1.7 MAC the response to EFS was significantly more reduced than that to ACh. We conclude that halothane, enflurane, and isoflurane attenuated airway constriction by several mechanisms, including 1) reduced excitability of the postsynaptic nicotinic receptors of the intramural parasympathetic ganglia and 2) an effect on the smooth muscle and/or on the muscarinic receptors.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailDescription des restes contenus dans un échantillon concrétionné découvert au Titelberg.
Gerrienne, Philippe ULg; Fairon-Demaret, Muriel ULg; Cordy, Jean-Marie ULg

in Bulletin de la Société Préhistorique du Luxembourg (1991), 13

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See detailSténose de l'artère rénale droite par les piliers du diaphragme. A propos d'un cas
Vahdat, H.; CREEMERS, Etienne ULg; Limet, Raymond ULg

in Journal des Maladies Vasculaires (1991), 16(3), 304-7

We present one case of arterial hypertension that had rapidly developed in a 23-year-old patient. Arteriography demonstrates a light stenosis of the root of the right renal artery and an obstruction of ... [more ▼]

We present one case of arterial hypertension that had rapidly developed in a 23-year-old patient. Arteriography demonstrates a light stenosis of the root of the right renal artery and an obstruction of the superior mesenteric artery. After an attempt of intraluminal dilatation had failed, we decided to carry out double revascularization with a venous graft. Postoperative control arteriography demonstrated early thrombosis in both grafts. Our second operation directly approached the lesion on the root of the renal artery, which was stenosed by muscle fibers from the right column of the diaphragm muscle. The resection of these fibers released the renal artery, which was otherwise normal, as was confirmed by the postoperative arteriogram. In a second part, we discuss the etiology of this double stenosis and our surgical strategy. [less ▲]

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See detailC.R. de J. CASTAÑO-RUIZ, El atuendo en la obra de Frederi Mistral
Henrard, Nadine ULg

in Revue Belge de Philologie et d'Histoire (1991), 69

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See detailIntérêt de la différence aterio-veineuse en O2 dans l'approche thérapeutique de l'hypertension intracrânienne post-traumatique
Franssen, Christine ULg; Hans, Pol ULg; Deprez, Josette ULg et al

in Agressologie : Revue Internationale de Physio-Biologie et de Pharmacologie Appliquées aux Effets de l'Agression (1991), 32(6-7), 366-368

Elevated intracranial pressure (ICP) is undoubtedly a determinant factor of outcome in severe head injured patient. Until now, medical treatment of elevated ICP in diffuse brain lesions consisted of ... [more ▼]

Elevated intracranial pressure (ICP) is undoubtedly a determinant factor of outcome in severe head injured patient. Until now, medical treatment of elevated ICP in diffuse brain lesions consisted of hyperventilation, CSF drainage, mannitol and barbiturates without accurate selection criteria. In fact, in comatose patients, the cerebral blood flow (CBF) can vary independently of the cerebral metabolic rate of oxygen (CMRO2) which is typically reduced. The venous oxygen saturation (SjO2) measured in the jugular bulb and the arterial-jugular oxygen difference (ajDO2) can be used for more appropriately selecting therapeutic measures. According to the following equation: CMRO2 = CBF x ajDO2, the measurement of the changes in ajDO2 might serve as an indicator of CBF adequacy, out of the presence of cerebral ischemia. A decreased ajDO2 suggests that CBF is excessive for cerebral metabolic requirements and an elevated ajDO2 indicates a decreased CBF. Consequently, treatment of elevated ICP in the presence of a low ajDO2 should be more oriented towards moderate hyperventilation and administration of metabolic depressive agents with maintenance of normal arterial blood pressure. Conversely, in case of high ajDO2, ICP control should aim to increase CBF by maintaining normocapnia, improving hemodynamic status or reducing extravascular volume accordingly. [less ▲]

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See detailIntérêt de l'électromyostimulation de basse fréquence dans la rééducation du quadriceps
Constant, T.; Vanderthommen, Marc ULg

in STAPS : Revue Internationale des Sciences du Sport et de l'Education Physique (1991), 24

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See detailStudy of the properties of fix new siderophores produced by fluorescent Pseudomonas
Ongena, Marc ULg; Jacques, Ph.; Delfosse, Ph. et al

in Archives Internationales de Physiologie et de Biochimie (1991), 99(B71),

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See detailUn exemple d'étude dendrochronologique: la charpente de la chapelle Saint_hubert à Weweler (Burg-Reuland)
Hoffsummer, Patrick ULg

in Bulletin de la Fondation Vanhove-Vonneche (1991), 3

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See detailL'immersion dans la vie professionnelle dès la formation initiale : pourquoi ?
Beckers, Jacqueline ULg

in Revue de la Direction Générale de l’Organisation des Etudes (1991), 2

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See detailLobeline-Induced Hyperpnea in Equids. Comparison with Rebreathing Bag and Exercise
Art, Tatiana ULg; Desmecht, Daniel ULg; Amory, Hélène ULg et al

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (1991), 38(2), 148-152

In order to facilitate lung auscultation, a transitory hyperpnea may be obtained by lobeline administration, use of a rebreathing bag or exercise. The effect of these three methods on the pulmonary ... [more ▼]

In order to facilitate lung auscultation, a transitory hyperpnea may be obtained by lobeline administration, use of a rebreathing bag or exercise. The effect of these three methods on the pulmonary function were studied and compared in 5 healthy ponies. Respiratory airflow and tidal volume were measured with a pneumotachograph Nr. 5 and pleural pressure with the esophageal balloon catheter technique. Pulmonary function values were measured before, during and after the hyperpnea induced by (i) lobeline, (ii) rebreathing and (iii) exercise. Lobeline administration induced an hyperpnea due to both an increase in tidal volume and respiratory rate; this increase in ventilation lasted for about 90 s and was accompanied by a sharp rise in the respiratory peak airflows, especially the expiratory ones. The rebreathing method induced a less hyperpnea which lasted only 30 s. Lastly the hyperpnea after a light treadmill exercise was the longer in duration and intermediate between the preceding methods in intensity [less ▲]

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See detailLes innovations dans l'intervention sociale et la justice des mineurs en Belgique
Born, Michel ULg

in Revue Internationale de Criminologie et de Police Technique (1991), 4

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See detailMechanical Properties of the Isolated Equine Trachea
Art, Tatiana ULg; Lekeux, Pierre ULg

in Research in Veterinary Science (1991), 51(1), 55-60

In order to study the in vitro mechanical properties of the equine trachea submitted to the compressive pressures observed in vivo, the pressure-volume relationship was determined in intra- and extra ... [more ▼]

In order to study the in vitro mechanical properties of the equine trachea submitted to the compressive pressures observed in vivo, the pressure-volume relationship was determined in intra- and extra-thoracic tracheal segments taken post mortem from 29 healthy horses (one to 15 years old; 352 to 651 kg). At the same time, the cross-sectional lumen area (X-SA) at the mid-point of the segment was measured using a slit-lamp transillumination and photographic measurement by endoscopy. The tracheal specific compliance (Cs) as well as the relative changes in X-SA and in the sagittal and transverse diameters, for intraluminal pressures from 5 to - 5 kPa, were calculated. The extrathoracic tracheal Cs was 0.060 +/- 0.002 kPa-1 and, at an intraluminal pressure of - 5 kPa, X-SA was reduced to about 73 per cent of its resting value. The intrathoracic segments were more compliant and, at similar compressive pressure, their X-SA was more reduced. These data show that the equine tracheal compliance is high and suggest that the increase in pulmonary resistance observed during strenuous exercise may be partly explained by a partial tracheal collapse. [less ▲]

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See detailPlasma evolution of testosterone, insulin-like growth factor-I and IGF-I binding protein capacities around puberty in cattle
Massart, Serge; Renaville, Robert ULg; Sneyers, Myriam et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1991), 99

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See detailLes abus sexuels et l’inceste
Glowacz, Fabienne ULg

in Revue d’Action sociale (1991), 1/2

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See detailPast and Future CFC and other trace gas warming: results from a seasonal climate model
Hauglustaine, Didier A.; Gérard, Jean-Claude ULg

in Annales Geophysicae [= ANGEO] (1991), 9

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See detailAutomatic Determination of Diltiazem and Desacetyldiltiazem in Human Plasma Using Liquid-Solid Extraction on Disposable Cartridges Coupled to Hplc--Part I: Optimization of the Hplc System and Method Validation
Hubert, Philippe ULg; Chiap, Patrice ULg; Crommen, Jacques ULg

in Journal of Pharmaceutical & Biomedical Analysis (1991), 9(10-12), 877-882

A sensitive and automated method for the analysis of diltiazem and desacetyldiltiazem in plasma has been developed using liquid-solid extraction (LSE) on disposable extraction cartridges (DECs) in ... [more ▼]

A sensitive and automated method for the analysis of diltiazem and desacetyldiltiazem in plasma has been developed using liquid-solid extraction (LSE) on disposable extraction cartridges (DECs) in combination with HPLC. After isolation from plasma, the analytes are separated on a highly deactivated octyl silica column with a mobile phase of methanol-0.05 M phosphate buffer (pH 7.4) (62:38, v/v). The analytes are monitored photometrically at 238 nm. The complete preparation of the plasma sample as well as the injection of the final extract on to the analytical column are performed automatically by means of a sample processor equipped with a robotic arm to which is attached a needle dispensing the different liquids. The internal standard solution is first added to the plasma sample. The DEC is then conditioned successively with methanol and phosphate buffer (pH 7.4). A 1.0-ml volume of sample containing the internal standard solution is applied on an extraction cartridge filled with cyanopropyl silica (50 mg). After the DEC has been washed with the same buffer, the analytes are eluted with 0.16 ml of methanol. A 0.14-ml volume of buffer is then passed through the DEC and 0.25 ml of the final extract is injected onto the HPLC column. The absolute recoveries of the drugs are about 90% and the limit of detection for diltiazem is 0.8 ng ml-1. Relative standard deviations of 2.6% (within-day) and 3.7% (between-day) have been obtained for this compound at a plasma concentration of 50 ng ml-1. [less ▲]

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See detailCompte rendu de J. Jouanna, Hippocrate. Tome V, 1e partie. Des vents. De l'art, Paris, 1988
Marganne, Marie-Hélène ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1991), 60

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See detailAmino acid composition and digestibility of four protein sources for dogs.
Neirinck, K.; Istasse, Louis ULg; Gabriel, Annick ULg et al

in Journal of Nutrition (1991), 121(11 Suppl), 64-5

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See detailInterprétation et rectification des jugements répressifs
Masset, Adrien ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1991)

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See detailEffects of specific dopaminergic agonists and antagonists in the open-field test.
Bruhwyler, J.; Chleide, E.; Liégeois, Jean-François ULg et al

in Pharmacology, Biochemistry & Behavior (1991), 39(2), 367-71

It has been found that dopaminergic transmission could be involved in some aspects of anxiety. The present study aims to explore this hypothesis further, using specific DA1 (SKF 38393) and DA2 ... [more ▼]

It has been found that dopaminergic transmission could be involved in some aspects of anxiety. The present study aims to explore this hypothesis further, using specific DA1 (SKF 38393) and DA2 (bromocriptine) agonists or DA1 (SCH 23390), and DA2 (zetidoline) antagonists in the open-field test. The results confirm previous studies indicating that DA1 and DA2 agonists predominantly increase locomotor activity, while DA1 and DA2 antagonists predominantly decrease it. However, at low doses, the four drugs increase the peripheral ambulation score significantly and, with the exception of zetidoline, also increase the central ambulation score. The observations made with zetidoline confirm the hypothesis that a specific presynaptic DA2 antagonism could be determinant for the disinhibitory effects of low doses of neuroleptics. A collateral action on 5HT transmission is also suggested to explain an hypothetic anxiolytic action of DA agonists and SCH 23390 at lower doses. [less ▲]

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See detailLarge-scale eradication of rabies using recombinant vaccinia-rabies vaccine
Brochier, Bernard; Kieny, M. P.; Costy, F. et al

in Nature (1991), 354(19/26 December), 520-521

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See detailStructure du méthyl-4 pipérazinyl-1)-10 pyrido[4,3-b][1,4]benzothiazépine
Dupont, L.; Dideberg, O.; Liégeois, Jean-François ULg et al

in Acta Crystallographica Section C-Crystal Structure Communications (1991), C47

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See detailMalignant cell attachment to endothelium of ex vivo perfused human umbilical vein. Modulation by platelets, plasma and fibronectin.
Lewalle, J. M.; Castronovo, Vincenzo ULg; Goffinet, G. et al

in Thrombosis Research (1991), 62(4), 287-98

The success of blood-born metastatic spread depends upon a key event: the tumor cell arrest and attachment to the host organ vasculature. In the present study, we have investigated interactions between ... [more ▼]

The success of blood-born metastatic spread depends upon a key event: the tumor cell arrest and attachment to the host organ vasculature. In the present study, we have investigated interactions between several normal and cancer cell lines and vascular endothelium in a model of ex vivo perfusion of human umbilical vein. In this system, hydrodynamic parameters are monitored and endothelial cells are kept in their original environment known to modulate their phenotype. Metastatic tumor cell adhesion to the perfused endothelium was found to be significantly higher than that of normal cells tested. Platelets and soluble plasma factors including fibronectin promoted tumor cell arrest and adhesion to endothelium. Altogether our results indicate that the ex vivo perfusion of human umbilical vein allows the study of the interactions between malignant tumor cells, circulating plasma or blood cells and the endothelium during blood-born metastatic spread. [less ▲]

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See detailMyeloperoxidase and elastase as markers of leukocyte activation during cardiopulmonary bypass in humans
Faymonville, Marie ULg; Pincemail, Joël ULg; Duchateau, J. et al

in Journal of Thoracic and Cardiovascular Surgery (The) (1991), 102

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See detailInterpleural, intercostal and thoracic epidural analgesia
Joris, Jean ULg

in Current Opinion in Anaesthesiology (1991), 4

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See detailAbcès thyroïdien a streptocoque pneumoniae associé à un goitre nodulaire toxique. A propos d'un cas
Panas, N.; Zgheib, A.; Desaive, Claude ULg et al

in Annales de Chirurgie (1991), 45(5), 429-31

An unusual case of acute suppurative thyroiditis in association with toxic nodular goiter is reported by the authors. Surgical therapy was necessary due to the severity of the local and systemic ... [more ▼]

An unusual case of acute suppurative thyroiditis in association with toxic nodular goiter is reported by the authors. Surgical therapy was necessary due to the severity of the local and systemic inflammation induced by this association. [less ▲]

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See detailStructures du 11-formyl-5-(4-méthylpipérazin-1-yl)-11H-pyrido[2,3b][1,5]benzodiazépine et du 6-(4-méthylpipérazin-1-yl)-11-méthyl-11H-pyrido[2,3-b][1,4]benzodiazépine
Dupont, L.; Englebert, S.; Dideberg, O. et al

in Acta Crystallographica Section C-Crystal Structure Communications (1991), C47

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See detailAllowed and Forbidden Transitions in Highly Ionized Neon-like Atoms (Ni XIX - ULXXXIII)
Quinet, Pascal ULg; Gorlia, T.; Biémont, Emile ULg

in Physica Scripta (1991), 44

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See detailValidation of the Thermodilution Technique for the Estimation of the Cardiac Output in the Unsedated Calf
Amory, Hélène ULg; Linden, Annick ULg; Desmecht, Daniel ULg et al

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (1991), 38(6), 409-417

The purpose of this study was to establish a standardized protocol in order to obtain accurate and reproducible cardiac output (CO) measurements by the thermodilution technique in the unsedated calf. In 5 ... [more ▼]

The purpose of this study was to establish a standardized protocol in order to obtain accurate and reproducible cardiac output (CO) measurements by the thermodilution technique in the unsedated calf. In 5 healthy calves, the effect of various temperatures, volumes, rates, means and sites of injection of the thermal indicator were tested for their effect on accuracy and reproducibility of CO measurement by the thermodilution technique, the Fick method being used as the standard technique. Five milliliters of an iced 5% dextrose solution per 100 kg body weight constituted the correct amount of thermal indicator. Manual injection of the indicator bolus and/or injection of this bolus through the proximal lumen of a thermodilution Swan-Ganz catheter gave poor results of CO measurements by the thermodilution technique. On the other hand, results of CO measurements were highly reliable when the bolus injection was performed by an ECG-synchronized injection pump and/or through a right atrial catheter with a larger diameter and a shorter length than the classical Swan-Ganz catheter. It was concluded that an iced 5% solution of dextrose (5 ml/100 kg body weight) injected through a right atrial catheter by an ECG-synchronized pump gives the most accurate and reproducible CO measurements by the thermodilution technique in unsedated calves. [less ▲]

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See detailGerminal centres and the immune response - Discussion
Cebra, J.; Schrader, C.; Shroff, K. et al

in Research in Immunology (1991), 142

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See detailL’ordinateur pour apprendre le latin
Denooz, Joseph ULg

in EVPRHOSYNE (1991), 19

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See detailLa cellule beta dans le diabète de type II: coupable ou victime?
SCHEEN, André ULg; Paquot, Nicolas ULg; Lefebvre, P. J.

in Journées Annuelles de Diabetologie de l'Hôtel-Dieu (1991)

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See detailLe test ELISA, une nouvelle voie rapide de determination de residus d'herbicides dans le sol. Application au cas de l'isoproturon.
Liegeois, E.; Dehon, Y.; Deleu, R. et al

in Mededelingen van de Faculteit Landbouwwetenschappen (Rijksuniversiteit te Gent) (1991), 56(3a),

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See detailNEW ROTATIONAL ANALYSIS OF THE ALPHA-1-PI-CHI-1-SIGMA+ TRANSITION OF ALBR
BREDOHL, Harald; DUBOIS, Iwan; Mahieu, Emmanuel ULg et al

in Journal of Molecular Spectroscopy (1991), 145(1), 12-17

Twenty-eight bands of the A1Π-X1Σ+ transition have been fully analyzed. The vibrational constants obtained for the A1Π state do not agree with earlier data. On the other hand the observations suggest that ... [more ▼]

Twenty-eight bands of the A1Π-X1Σ+ transition have been fully analyzed. The vibrational constants obtained for the A1Π state do not agree with earlier data. On the other hand the observations suggest that the conclusion about the predissociation ought to be revised. [less ▲]

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See detailCompte rendu de R.C. Maulitz, D.E. Long, Grand Rounds. One Hundred Years of Internal Medicine, Philadelphie, 1988
Marganne, Marie-Hélène ULg

in Archives Internationales d'Histoire des Sciences (1991), 41

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See detailThe stratigraphy of the Middle Devonian in Belgium
Bultynck, P; Coen-Aubert, M; Godefroid, J et al

in Memoirs of the Geological Survey of Belgium (1991), 30

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See detailLe point sur l'evolution dans le domaine des formulations.
Schiffers, Bruno ULg; Galoux, M.

in Parasitica (1991), 47(2-3),

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See detailBranchial Arch Anomalies in Trisomy 18
Verloes, Alain ULg; Seret, N.; Bernier, V. et al

in Annales de Génétique (1991), 34(1), 22-4

The authors report two newborns and one fetus with trisomy 18, who have severe anomalies of the first branchial arch: extreme microtia with imperforate external meatus in two cases, and hemifacial ... [more ▼]

The authors report two newborns and one fetus with trisomy 18, who have severe anomalies of the first branchial arch: extreme microtia with imperforate external meatus in two cases, and hemifacial microsomia in a third one. Those cases point to the huge phenotypic variability of the trisomy 18. [less ▲]

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See detailApport du genie genetique en production animale.
Portetelle, Daniel ULg

in Bulletin des Recherches Agronomiques de Gembloux (1991), 26(2),

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See detailSuperconductivity fluctuations in Bi(Pb) based granular ceramics superconductors: evidence for fractal behavior
Ausloos, Marcel ULg; Laurent, Christian; Patapis, S. K. et al

in Zeitschrift für Physik. B, Condensed Matter (1991), 83(3), 355-359

We report precise measurements of the electrical resistivity in three different Bi(Pb) based granular ceramics superconductors. We show that a single critical exponent (5/6) describes the ... [more ▼]

We report precise measurements of the electrical resistivity in three different Bi(Pb) based granular ceramics superconductors. We show that a single critical exponent (5/6) describes the superconductivity fluctuations. Such a critical exponent indicates a fractal behavior of the superconducting path. Our results thus indicate a strict two dimensional fluctuation percolation set (below the superconductivity onset temperature 195 K down to T(c)), and provide some proof for Tarascon et al. "shell conductivity path" hypothesis. We estimate the shell thickness to be of the order of 10 angstrom. [less ▲]

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See detailThe Photoionization of Ammonia revisited. The Vibrational Autoionization of NH3 and its three Isotopomers in the 10-12 eV photon energy range.
Locht, Robert ULg; Leyh, Bernard ULg; Denzer, W. et al

in Chemical Physics (1991), 155

The photoionzation efficiency curves of NH3 and its three isotopomers have been investigated in the photon energy range of the first ionized state. From the analysis of the corresponding vibrational ... [more ▼]

The photoionzation efficiency curves of NH3 and its three isotopomers have been investigated in the photon energy range of the first ionized state. From the analysis of the corresponding vibrational structure, wavenumbers and anharmonicity constants are deduced. The detailed investigation of the abundant autoionization structure tends to show the adiabatic ionization energy to be 10.072+/-0.010 eV for NH3, NH2D and NHD2 and 10.083+/-0.010 eV for ND3. All autoionization features were classified in vibrational progressions (nu2 bending mode) belonging to nasa1 (or nd) and npe (n=5, 6, 7) Rydberg series. Vibrational autoionization occurs through Delta v transitions up to -9. A qualitative analysis of the intensity distribution of these series strongly supports that transitions involving odd Delta v values are favoured. This observation can be understood by applying group theoretical considerations to the theory of vibrational autoionization. [less ▲]

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See detailCharacterization of an unusual thyroid response unit in the promoter of the human placental lactogen gene
Voz, Marianne ULg; Peers, Bernard ULg; Belayew, Alexandra et al

in Journal of Biological Chemistry (1991), 266(20), 13397-404

The human placental lactogen B (hCS-B) promoter activity is strongly stimulated by thyroid hormones in the rat pituitary GC cell line. The minimal DNA sequence required for stimulation, as determined by ... [more ▼]

The human placental lactogen B (hCS-B) promoter activity is strongly stimulated by thyroid hormones in the rat pituitary GC cell line. The minimal DNA sequence required for stimulation, as determined by transfection with 5' and 3' deletion mutants, spans 67 base pairs, from coordinate -97 to -31. DNase I footprinting experiments show that this thyroid response unit includes two adjacent binding sites: one for the thyroid receptor (-67/-41), the other for the pituitary-specific factor GHF1 (-95/-68). Neither region alone is sufficient to confer thyroid responsiveness. The thyroid receptor binding element (TBE) does not contain any repeats or palindromes but is composed of two different domains, one of which is very similar to the half-palindromic motif described by Glass et al. (Glass, C.K., Holloway, J.M., Devary, O.L., and Rosenfeld, M.G. (1988) Cell 54, 313-323). The other is very rich in purine. The normal human growth hormone (hGH-N) promoter, which is 94% similar to the hCS-B promoter, differs from its hCS-B counterpart precisely in this TBE. This difference may explain the opposite 3,5,3'-triiodothyronine (T3) regulation of these two genes. [less ▲]

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See detailEradication de la leucose bovine enzootique en Belgique : estimation du temps nécessaire à l'assainissement des foyers découverts
Knapen, K.; Kerkhofs, P.; Palm, Rodolphe ULg et al

in Annales de Médecine Vétérinaire (1991), 135(4), 281-285

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See detailLaminin receptor complementary DNA-deduced synthetic peptide inhibits cancer cell attachment to endothelium.
Castronovo, Vincenzo ULg; Taraboletti, G.; Sobel, M. E.

in Cancer Research (1991), 51(20), 5672-8

Stable attachment of cancer cells to the endothelium is a key step in the formation of metastasis. In this study, we have investigated the possibility that interaction between laminin and its Mr 67,000 ... [more ▼]

Stable attachment of cancer cells to the endothelium is a key step in the formation of metastasis. In this study, we have investigated the possibility that interaction between laminin and its Mr 67,000 high-affinity receptor (67 LR) could play a major role in this process. Scatchard analysis of laminin-binding studies showed that bovine aortic endothelial cells exhibit 46,000 high-affinity receptors that mediate, at least in part, the attachment of highly invasive melanoma cells. This endothelial cell-melanoma cell interaction was significantly inhibited by soluble laminin and by anti-laminin antibodies. Peptide G, an eicosapeptide derived from the complementary DNA sequence of the 67 LR precursor (IPCNNKGAHSVGLMWWMLAR) that specifically binds to laminin and presumably contains the active ligand-binding site of the receptor, specifically prevented attachment of the melanoma cells to both the bovine aortic endothelial cell monolayer and human umbilical vein endothelium. Thus, peptide G may selectively interfere with the metastatic cascade by inhibiting tumor cell attachment to endothelium via the laminin-67 LR pathway and is a potential new antimetastatic agent. [less ▲]

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