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See detailComparative performance study of postal services: a productive efficiency approach
Pestieau, Pierre ULg; Perelman, Sergio ULg

in Annales d'Economie et de Statistique (1994), (33), 187-202

This paper first discusses the notion of economic performance as applied to public enterprises and argues that productive efficiency is an attractive approach to performance measurement for such firms. It ... [more ▼]

This paper first discusses the notion of economic performance as applied to public enterprises and argues that productive efficiency is an attractive approach to performance measurement for such firms. It then presents an empirical efficiency study of postal services which is aimed at comparing productive performance indicators across countries and at testing the effect of competition and regulation on these indicators. [less ▲]

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See detailA recombinant viral haemorrhagic septicaemia virus glycoprotein expressed in insect cells induces protective immunity in rainbow trout
Lecocq-Xhonneux, F.; Thiry, M.; Dheur, I. et al

in Journal of General Virology (The) (1994), 75

Viral haemorrhagic septicaemia (VHS) is a fish rhabdovirus infection of world-wide importance. Control policies have been established but the disease still causes heavy losses in fish farming. The ... [more ▼]

Viral haemorrhagic septicaemia (VHS) is a fish rhabdovirus infection of world-wide importance. Control policies have been established but the disease still causes heavy losses in fish farming. The development of a recombinant subunit vaccine was initiated to produce a safe and effective vaccine to protect fish against VHS. The VHS virus (VHSV) glycoprotein, which induces neutralizing antibodies in rainbow trout, was chosen for expression in insect cells using a baculovirus vector. The Mr of the recombinant protein estimated by SDS-PAGE was slightly lower than that of the native viral protein. The recombinant protein displayed different degrees of glycosylation and was recognized in ELISA by neutralizing antibodies. It was transported to the plasma membrane of insect cells where its ability to induce membrane fusion was preserved. The efficacy of the recombinant protein as a vaccine was compared with those of an inactivated and an attenuated vaccine. When injected intraperitoneally into rainbow trout, the baculo-virus-encoded protein was shown (i) to induce the synthesis of VHSV-neutralizing antibodies and (ii) to confer protection against virus challenge. Immunization performed by immersion failed. This is the first report of a recombinant vaccine that protects fish against VHSV. [less ▲]

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See detailL'hémorragie pulmonaire induite par l'exercise chez le cheval
Art, Tatiana ULg; Lekeux, Pierre ULg

in Pratique Vétérinaire Equine (1994), 26(1), 15-24

This review analyses the epidemiology, etiology, anatomo- and physiopathology, diagnosis and prevention of the syndrome of exercise-induced pulmonary hemorrhage in horses.

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See detailGrowth-inhibiting effects of a neem-based insecticide (Margosan-O) against Spodoptera littoralis (Lepidoptera: Noctuidae
Haubruge, Eric ULg; Seck, Dogo; Hemptinne, Jean-Louis et al

in Insect Science and its application (1994), 15(4), 243-249

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See detailFlow modeling in an underground gasifier at great depth by the Boundary-Element Method
MATHY, B.; PIRLOT, Pierre; Pirard, Jean-Paul ULg et al

in In Situ (1994), 18(4), 399-418

In order to simulate the cavity growth of an underground gasifier in thin seams at great depth, Wilks1 has developed an original model that solves the continuity equation in the horizontal plane with the ... [more ▼]

In order to simulate the cavity growth of an underground gasifier in thin seams at great depth, Wilks1 has developed an original model that solves the continuity equation in the horizontal plane with the hypothesis of radial fluid flow around the injection well. In the model presented here, the continuity equation in the horizontal plane has been taken into account, removing the limiting assumption on flow (radial direction) assumed by Wilks. The simultaneous solution of the continuity equation and the Darcy law has been carried out using the Boundary Element Method (BEM); this method is particularly suitable for solving problems where boundary conditions are of prime importance. The model enables the influences of the permeability of the medium and gasifier geometry to be demonstrated. [less ▲]

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See detailEtude épidémiologique de la toxoplasmose chez les femmes enceintes à Amiens (Picardie). Nécessité d'une enquête nationale
Carme, Bernard; Lenne, Evelyne; Tirard, Véronique et al

in Médecine et Maladies Infectieuses (1994), 24

L'étude avait pour but d'évaluer le niveau d'immunité vis à vis de la toxoplasmose des femmes venant d'accoucher à Amiens entre mars 1993 et avril 1994 ainsi que leur connnaissance des mesures préventives ... [more ▼]

L'étude avait pour but d'évaluer le niveau d'immunité vis à vis de la toxoplasmose des femmes venant d'accoucher à Amiens entre mars 1993 et avril 1994 ainsi que leur connnaissance des mesures préventives vis à vis de cette parasitose. Cette étude a permis de mettre en évidence la bonne connaissance des mesures préventives vis à vis de la toxoplasmose chez les femmes non immunes. Ceci a permis également de préciser les données épidémiologiques de la toxoplasmose à Amiens. Le choix d'un protocole incluant les femmes au moment de l'accouchement pourrait être complété par celui de femmes en début de grosesse pour éviter d'exclure les interruptions de grossesse. Cette étude devrait déboucher sur une enquête nationale qui permettrait de préciser l'épidémiolgoie de la toxoplasmose en France. [less ▲]

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See detailLe projet d'entreprise d'insertion: son impact en termes budgétaires et d'emplois
Defourny, Jacques ULg; Lequet, Nathalie; Tilkin, Michel

in Reflets et Perspectives de la Vie Economique (1994), XXIII(1-2), 157-171

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See detailAcute biochemical variations induced by four different calcium salts in healthy male volunteers
Reginster, Jean-Yves ULg; Denis, D; Bartsch, V et al

in Equilibre (1994), 19

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See detailLifetime Measurements for the 4p2P° and 5p2P° Levels and calculation of Transition Probabilities in Na I
Lowe, R. M.; Biémont, Emile ULg

in Journal of Physics : B Atomic Molecular & Optical Physics (1994), 27

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See detailNONEQUILIBRIUM EFFECTS IN THE THERMAL-CONDUCTIVITY OF BI-BASED HIGH-TEMPERATURE SUPERCONDUCTORS
Bougrine, Hassan ULg; SERGEENKOV, S.; Ausloos, Marcel ULg et al

in Solid State Communications (1994), 91(7), 571-575

Thermal conductivity of two Bi-based high temperature superconducting ceramics, 2212 and 2223, with a markedly different microstructure have been examined. A pulse technique has been used. Depending on ... [more ▼]

Thermal conductivity of two Bi-based high temperature superconducting ceramics, 2212 and 2223, with a markedly different microstructure have been examined. A pulse technique has been used. Depending on the heating pulse duration, the more weak-links-containing 2223 sample shows either equilibrium or nonequilibrium behavior. The temperature dependence of the thermal conductivity between 110 K and 180 K is found to obey the Arrhenius law. The experimental observations are interpreted as a thermally activated heat flux motion through the polycrystalline grain boundaries with an energy barrier of nearly 10meV. It is likely due to a phase slip mechanism. An extra relaxation process due to the pore content/structure is thus emphasized in such regimes. [less ▲]

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See detailRécidive post-opératoire de la maladie de Crohn après chirurgie curatrice
Belaiche, Jacques ULg; Louis, Edouard ULg

in Médecine et Hygiène (1994), 52

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See detailEffect of the emulsion stability on the morphology and porosity of semicrystalline poly-L-lactide micriparticles prepared by w/o/w double emulsion-evaporation
Schugens, Ch; Laruelle, N; Nihant, N et al

in Journal of Controlled Release (1994), 32

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See detailQuantitative Assessment of Aerial Ammonia Toxicity to the Nasal Mucosa by Use of the Nasal Lavage Method in Pigs
Urbain, B.; Gustin, Pascal ULg; Prouvost, J. F. et al

in American Journal of Veterinary Research (1994), 55(9), 1335-1340

Effects of atmospheric ammonia (NH3) on the nasal mucosa and somatic growth were investigated in pigs exposed to 4 NH3 concentrations (0; 25; 50; and 100 ppm) for 6 days in a specifically designed air ... [more ▼]

Effects of atmospheric ammonia (NH3) on the nasal mucosa and somatic growth were investigated in pigs exposed to 4 NH3 concentrations (0; 25; 50; and 100 ppm) for 6 days in a specifically designed air-pollutant exposure chamber. Nasal lavage (NAL) was applied to quantify the ammonia-induced inflammatory response by measuring the number of neutrophils and the albumin (porcine serum albumin) concentration in the NAL liquid. In control pigs, these variables remained unchanged throughout the exposure period. In all other groups, an important ammonia concentration-related increase was recorded. The equation of the linear regression line established between the mean values of the number of neutrophils (x 10(3)) per milliliter of NAL liquid (y) recorded at the end of the exposure period and the ammonia concentrations (ppm) was: y = 69.7 + 3.3 [NH3] (r = 0.979; P < 0.020). The increase in the neutrophil count was significant (P < 0.05) at concentrations as low as 25 ppm. For albumin concentration nanograms per milliliter, the corresponding equation was: y = 574 + 14.3 [NH3] (r = 0.953; P < 0.045). However, the first significant change (P < 0.05) in this variable was only obtained for the higher concentration (100 ppm). In exposed pigs, a concentration-related depression of somatic growth was observed. The equation of the regression line plotted relating the individual values of the changes in body weight gain recorded over the exposure period expressed as percentage of the initial body weight (y) and the ammonia concentration was: y = 3.507-0.203 [NH3] + 0.001 [NH3]2 (r = 0.55; P < 0.010).(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailTechniques moleculaires de detection et d'identification des agents phytopathogenes.
Lepoivre, Philippe ULg; Kummert, J.; Colinet, D. et al

in Cahiers Agricultures (1994), 3(4),

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See detailMolecular Analysis Of The Ycr-242 Gene Encoding The Putative Mitochondrial Asparaginyl-Transfer-Rna Synthetase From Saccharomyces-Cerevisiae
Landrieu, I.; Vandenbol, Micheline ULg; Portetelle, Daniel ULg et al

in Archives Internationales de Physiologie de Biochimie et de Biophysique (1994), 102(2),

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See detailModifier les représentations de l'échec à l'école normale
Beckers, Jacqueline ULg

in Recherche en Education. Théorie & Pratique (1994), 18-19

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See detailEffects of Atmospheric Ammonia on Pulmonary Hemodynamics and Vascular Permeability in Pigs: Interaction with Endotoxins
Gustin, Pascal ULg; Urbain, B.; Prouvost, J. F. et al

in Toxicology and Applied Pharmacology (1994), 125(1), 17-26

The influence of atmospheric ammonia on the somatic growth, the plasma cortisol and ammonia concentrations, and cell blood counts was investigated in pigs exposed to four concentrations (0, 25, 50, and ... [more ▼]

The influence of atmospheric ammonia on the somatic growth, the plasma cortisol and ammonia concentrations, and cell blood counts was investigated in pigs exposed to four concentrations (0, 25, 50, and 100 ppm) for 6 days in a specifically designed air-pollutants exposure chamber. The effects of this gas on pulmonary vascular hemodynamics and permeability and on the endotoxin-induced vascular response were also assessed using an isolated perfused lung preparation. The total pulmonary blood flow resistance (Rt) was partitioned into four components: arterial (Ra), pre-(Ra′) and post-(Rv′) capillary and venous (Rv). The capillary filtration coefficient (Kf,c) was evaluated by using a gravimetric technique. None of the concentrations of ammonia significantly modified the plasma cortisol and ammonia concentrations or the differential leukocyte percentages and total white blood cell count, suggesting an absence of stress related to ammonia. In exposed animals, lethargy and a concentration-related depression of the somatic growth were observed. The equation of the regression line plotted relating the mean values of the changes in body weight gain recorded over the exposure period expressed as percentages of the initial body weight (y) and ammonia concentrations (x) was: y = 3.204 − 0.177x + 0.001x2(r = 0.99; p≤0.013). Endotoxin infused in the perfusion liquid of lungs from unexposed animals for 180 min induced a significant 208% increase in Rt (p < 0.001) which can be ascribed to a 338 and 180% increase in Ra′ and Rv′, respectively. Endotoxin infusion also induced a 62% (p ≤ 0.001) increase in the Kf,c. Exposure of pigs to ammonia at any concentration did not modify the baseline values of any hemodynamic or permeability parameters. However, the hemodynamic response to endotoxins in lungs from pigs exposed to 100 ppm was significantly altered. The increase in Rt, Ra′, and Rv′ observed in unexposed pigs was completely abolished as shown by the limited changes in Rt (+34.9%). An intermediate reaction (+131.7%) was obtained in pigs exposed to 50 ppm. This inhibiting effect of ammonia was closely correlated with gas concentration by a linear regression (r = 0.99; p ≤ 0.037). The changes in the Kf,c recorded in the control group were not modified by exposure to ammonia. It was concluded that exposure of pigs to aerial ammonia concentrations from 0 to 100 ppm for 6 days has no direct effect on the pulmonary microvascular hemodynamics and permeability and induces no stress response. A marked depressive effect on the somatic growth is observed at concentrations greater than 25 ppm. Concentrations greater than 50 ppm can modulate the pulmonary vascular response to endotoxins [less ▲]

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See detailInsulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.
Peers, Bernard ULg; Sharma, S.; Teitelman, G. et al

in Molecular Endocrinology (1994), 8(12), 1798-806

The development of endocrine cell types within the pancreas is thought to involve the progressive restriction of pluripotential stem cells, which gives rise to the four major cell types: insulin ... [more ▼]

The development of endocrine cell types within the pancreas is thought to involve the progressive restriction of pluripotential stem cells, which gives rise to the four major cell types: insulin-, glucagon-, somatostatin-, and pancreatic polypeptide-expressing cells. The mechanism by which these peptide hormone genes are induced and then either maintained or repressed during development is unknown, but their coexpression in early precursor cells suggests the involvement of common regulatory factors. Here we show that the somatostatin transcription factor STF-1 is also a principal regulator of insulin expression in beta-cells of the pancreas. STF-1 stimulates the insulin gene by recognizing two well defined islet-specifying elements on the insulin promoter and by subsequently synergizing in trans with the juxtaposed helix-loop-helix protein E47. Within the STF-1 protein, an N-terminal trans-activation domain functions cooperatively with E47 to stimulate insulin transcription. As truncated STF-1 polypeptides lacking the N-terminal activation domain strongly inhibit insulin promoter activity in beta-islet cells, our results suggest that the specification of islet cell types during development may be in part determined by the expression of STF-1 relative to other islet cell factors. [less ▲]

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See detailSequence-Analysis Of A 40-Kb Dna Fragment From Chromosome-X Of Saccharomyces-Cerevisiae
Vandenbol, Micheline ULg; Bolle, Pa.; Dion, C. et al

in Archives Internationales de Physiologie de Biochimie et de Biophysique (1994), 102(2),

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See detailUtility of non-invasive ambulatory bood pressure monitoring in a hypertension clinic
Saint-Remy, Annie ULg; Dubois, Bernard ULg; Krzesinski, Jean-Marie ULg et al

in CVD Epidemiology newsletter (1994), 49(Spring), 50

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See detailEvolution of shoot density of the Posidonia seagrass bed of Calvi Bay (Corsica)
Soullard, Mady; Bourge, Isabelle; Fogel, Julie et al

in Vie et Milieu (1994), 44

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See detailCauses de mortalité et teneur en métaux lourds de Guillemots de Troïl Uria aalge échoués le long du littoral belge.
Bouquegneau, Jean-Marie ULg; Debacker, Virginie ULg; Antoine, Nathalie et al

in Bulletin de la Société Royale des Sciences de Liège (1994), 63(1-2), 211-217

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See detailPlasma IGF-I levels as predictive criteria of growth performances in cattle
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

in Growth Regulation (1994), 4(suppl 1), 115

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See detailPossessoire, pétitoire, référé, plainte, bornage et revendication ...Quand tout s'emmêle!
Lecocq, Pascale ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1994)

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See detailCrystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide
Merritt, E. A.; Sarfaty, S.; van den Akker, F. et al

in Protein Science : A Publication of the Protein Society (1994), 3(2), 166-75

Cholera toxin (CT) is an AB5 hexameric protein responsible for the symptoms produced by Vibrio cholerae infection. In the first step of cell intoxication, the B-pentamer of the toxin binds specifically to ... [more ▼]

Cholera toxin (CT) is an AB5 hexameric protein responsible for the symptoms produced by Vibrio cholerae infection. In the first step of cell intoxication, the B-pentamer of the toxin binds specifically to the branched pentasaccharide moiety of ganglioside GM1 on the surface of target human intestinal epithelial cells. We present here the crystal structure of the cholera toxin B-pentamer complexed with the GM1 pentasaccharide. Each receptor binding site on the toxin is found to lie primarily within a single B-subunit, with a single solvent-mediated hydrogen bond from residue Gly 33 of an adjacent subunit. The large majority of interactions between the receptor and the toxin involve the 2 terminal sugars of GM1, galactose and sialic acid, with a smaller contribution from the N-acetyl galactosamine residue. The binding of GM1 to cholera toxin thus resembles a 2-fingered grip: the Gal(beta 1-3)GalNAc moiety representing the "forefinger" and the sialic acid representing the "thumb." The residues forming the binding site are conserved between cholera toxin and the homologous heat-labile enterotoxin from Escherichia coli, with the sole exception of His 13. Some reported differences in the binding affinity of the 2 toxins for gangliosides other than GM1 may be rationalized by sequence differences at this residue. The CTB5:GM1 pentasaccharide complex described here provides a detailed view of a protein:ganglioside specific binding interaction, and as such is of interest not only for understanding cholera pathogenesis and for the design of drugs and development of vaccines but also for modeling other protein:ganglioside interactions such as those involved in GM1-mediated signal transduction. [less ▲]

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See detailEnzyme Immobilization in Nanoparticles produced by Inverse Microemulsion Polymerization
Daubresse, Catherine; Grandfils, Christian ULg; Jérôme, Robert ULg et al

in Journal of Colloid & Interface Science (1994), 168

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See detailTaqI restriction fragment length polymorphism for bovine growth hormone in bovine breeds selected for milk and/or meat
Renaville, Robert ULg; Sneyers, Myriam; Falaki, Mohammed et al

in Journal of Animal Science (1994), 72(suppl 1), 316

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See detailA note on the size-fractionated pigments of the phytoplankton of the Strait of Magellan (February-March 1991)
Saggiomo, Vincenzo; Mangoni, Olga; Borriello, C. et al

in Oebalia : International Journal of Marine Biology and Oceanography (1994), XX

During an oceanographic cruise, carried out at the end of the austral summer (February-March 1991) in the Strait of Magellan, spatial patterns of size-fractionated chlorophyll and primary production were ... [more ▼]

During an oceanographic cruise, carried out at the end of the austral summer (February-March 1991) in the Strait of Magellan, spatial patterns of size-fractionated chlorophyll and primary production were studied in relation to hydrographic patterns. Phytoplankton biomass, in terms of active Chl a, ranged between 10 and 51 mg m-2 and primary production between 275 and 1 170 mg C m-2 d-1. The most important features concern the confinement of the microphytoplanktonic fraction to the Pacific opening and to the embayements between the two Narrows. In the internal part of the Strait, an uniform dimensional structure (< 5 um) of phytoplankton communities was observed, with the picophytoplanktonic fraction always dominant. [less ▲]

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See detailSpatial patterns of phytoplanktonic pigments and primary production in a semi-enclosed periantarctic ecosystem: the Strait of Magellan
Saggiomo, Vincenzo; Goffart, Anne ULg; Carrada, Gian Carlo et al

in Journal of Marine Systems (1994), 5

The spatial patterns of nitrate, phytoplankton size-fractionated chlorophyll a, photosynthetic pigments detected by HPLC and primary production were studied at the end of the austral summer ... [more ▼]

The spatial patterns of nitrate, phytoplankton size-fractionated chlorophyll a, photosynthetic pigments detected by HPLC and primary production were studied at the end of the austral summer (February–March 1991), in the Strait of Magellan to provide insight into the mechanisms governing this seemi-enclosed periantartic ecosystem. Climatological peculiarities, hydrodynamic constraints, runoff and land forcing were considered. The most important features identified for this area were the confinement of the microphytoplankton fraction to the external parts of the Strait and the rather uniform dimensional structure of the phytoplankton communities ( < 5 μm) within the internal sectors. In particular, the nanoplanktonic fraction (10 - 2 μm) comprised 33 %, while the picoplanktonic one (2 - 0.5 μm) represented 62% of the total. The concentration of active Chl. a and plant pigments detected by HPLC, nitrate and primary production showed an uneven but similar distribution, allowing for the characterization of different sectors within the Strait, according to different types and intensities of forcing factors. The different ecological sectors identified along the Strait were associated with distinct hydrographic typologies: an oligotrophic, wind-mixed coastal area, adjacent to the Pacific opening; a high runoff fjord and a divergence zone in the Andean sectors; a stratified inland sea in the basin-like part of the channel (Paso Ancho) and a shallow, tidally mixed system in the Patagonian sectors. Areas of relatively low and high phytoplankton biomass and primary production alternate along the Strait, according to the hydrographic structures of the different sectors. Phytoplankton biomass, in terms of active Chl. a (spectrofluorometric determination) ranged between 10 and 51 mg m−2 and primary production between 275 and 1170 mg C m−2 d−1. The assemblage of plant pigments detected by HPLC indicated that the high levels of phytoplankton pigments and production were most likely attributable to Chlorophytes, Prasinophytes, Prymnesiophytes and/or Gyrodinium and Gymnodinium-like Dinoflagellates that were submitted to natural senescence and to superfluous feeding activity; while, when Diatoms, Cryptomonads and Prymnesiophytes were dominant, efficient zooplankton grazing occurred and characterized a balanced food chain. The spatial distribution of the parameters considered was related to hydrologic conditions indicating a Pacific water influence in the entire channel. [less ▲]

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See detailIsolation of the missing 5-end of the encoding region of the bovine leukemia virus cell receptor gene.
Ban, J.; Truong, A. T.; Horion, B. et al

in Archives of Virology (1994), 138(3-4),

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See detailMéléagre dans les Argonautiques
Renaud, Jean-Michel ULg

in Uranie : Mythes et Littératures (1994), 4

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See detailThe structures and catalytic mechanisms of active-site serine beta-lactamases.
Lamotte, Josette ULg; Knox, J.; Kelly, J. A. et al

in Biotechnology & Genetic Engineering Reviews (1994), 12

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See detailTechnical Study of Some Major Parameters Influencing the Performances of an Aerosol Delivery Equipment Suitable for Calves
Genicot, Bruno; Peckova, M.; Close, Roland et al

in Veterinary Research (1994), 25(5), 468-77

Aerosol delivery equipment, suitable for the treatment of bovine respiratory dysfunctions and including 2 parallelly positioned jet nebulizers, was studied in depth in order to determine the optimal ... [more ▼]

Aerosol delivery equipment, suitable for the treatment of bovine respiratory dysfunctions and including 2 parallelly positioned jet nebulizers, was studied in depth in order to determine the optimal working conditions in the field. Indeed, some factors might reasonably alter the performance of this equipment. Among these factors, the influences of the parallel position of jet nebulizers (in order to accommodate the breathing requirements of the cattle and achieve a rapid treatment), of the long feed pipe delivering compressed air (in order to keep the animal away from the compressor unit), and finally of the ambient temperature were studied, this equipment being essentially used during the winter season. This equipment could accommodate the breathing needs of cattle weighing up to 225 kg if a pressure of 600 kPa was developed upstream to the nebulizers. The rate of atomization was significantly reduced when working at ambient air temperatures (272.25 K < T < 274.65 K) close to those encountered in winter. This was especially true when pressure upstream to the nebulizers did not exceed 500 kPa. The immersion of the feed pipe for compressed air in hot water led to an increase in the rate of atomization without raising evaporative water losses, and reduced the drop in temperature in the nebulizer solution. Finally, the rate of atomization significantly increased when the face mask including the nebulizers was maintained so that the nebulizers were in a vertical position or at an angle not less than 60 degrees with respect to the ground. [less ▲]

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See detailDNase I hypersensitive sites far upstream of the rat tryptophan oxygenase gene direct developmentally regulated transcription in livers of transgenic mice.
Kaltschmidt, Christian; Muller, Marc ULg; Brem, Gottfried et al

in Mechanisms of Development (1994), 45(3), 203-10

Expression of the gene coding for tryptophan oxygenase (TO) is switched on in rat liver about two weeks after birth. We identified two clusters of DNaseI hypersensitive (HS) sites in the TO gene upstream ... [more ▼]

Expression of the gene coding for tryptophan oxygenase (TO) is switched on in rat liver about two weeks after birth. We identified two clusters of DNaseI hypersensitive (HS) sites in the TO gene upstream region; one near the promoter, the other at a distant upstream location (-8.5 kb). Hypersensitivity of upstream sites was present in adult and in 7 day old rat liver, but absent in kidney. To investigate their role in transcriptional regulation, a reporter gene controlled by both HS site regions was used to generate transgenic mice. In these animals the transgene followed the cell specific and developmental regulation of the endogenous gene: inactive after birth and active in adult liver. Transgenes containing only the promoter proximal HS site were non-functional. [less ▲]

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See detailDimensionless critical shear stress evaluation from flume experiments using different gravel beds
Petit, François ULg

in Earth Surface Processes & Landforms (1994)

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See detailThe experience of the CHU Liege with conservative surgery in the management of upper urinary tract tumors.
Bouffioux, Christian ULg; Andrianne, Robert ULg; Bonnet, Pierre ULg et al

in Acta Urologica Belgica (1994), 62(4), 39-43

A review of 20 cases of conservative surgery for urothelial tumors of the upper tract is presented. The morbidity is limited; the recurrence rate is around 15% in the ipsilateral urinary tract with a mean ... [more ▼]

A review of 20 cases of conservative surgery for urothelial tumors of the upper tract is presented. The morbidity is limited; the recurrence rate is around 15% in the ipsilateral urinary tract with a mean follow up of 41 months. Conservative surgery does not seem to carry a higher fatal risk as compared to more radical surgery. It has indications in some cases which are defined. [less ▲]

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See detailImproved Experimental and Theoretical Energy Levels of Neon I
Chang, E. S.; Schoenfeld, W. G.; Biémont, Emile ULg et al

in Physica Scripta (1994), 49

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See detailA comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group.
Serruys, P. W.; de Jaegere, P.; Kiemeneij, F. et al

in The New England journal of medicine (1994), 331(8), 489-95

BACKGROUND: Balloon-expandable coronary-artery stents were developed to prevent coronary restenosis after coronary angioplasty. These devices hold coronary vessels open at sites that have been dilated ... [more ▼]

BACKGROUND: Balloon-expandable coronary-artery stents were developed to prevent coronary restenosis after coronary angioplasty. These devices hold coronary vessels open at sites that have been dilated. However, it is unknown whether stenting improves long-term angiographic and clinical outcomes as compared with standard balloon angioplasty. METHODS: A total of 520 patients with stable angina and a single coronary-artery lesion were randomly assigned to either stent implantation (262 patients) or standard balloon angioplasty (258 patients). The primary clinical end points were death, the occurrence of a cerebrovascular accident, myocardial infarction, the need for coronary-artery bypass surgery, or a second percutaneous intervention involving the previously treated lesion, either at the time of the initial procedure or during the subsequent seven months. The primary angiographic end point was the minimal luminal diameter at follow-up, as determined by quantitative coronary angiography. RESULTS: After exclusions, 52 patients in the stent group (20 percent) and 76 patients in the angioplasty group (30 percent) reached a primary clinical end point (relative risk, 0.68; 95 percent confidence interval, 0.50 to 0.92; P = 0.02). The difference in clinical-event rates was explained mainly by a reduced need for a second coronary angioplasty in the stent group (relative risk, 0.58; 95 percent confidence interval, 0.40 to 0.85; P = 0.005). The mean (+/- SD) minimal luminal diameters immediately after the procedure were 2.48 +/- 0.39 mm in the stent group and 2.05 +/- 0.33 mm in the angioplasty group; at follow-up, the diameters were 1.82 +/- 0.64 mm in the stent group and 1.73 +/- 0.55 mm in the angioplasty group (P = 0.09), which correspond to rates of restenosis (diameter of stenosis, > or = 50 percent) of 22 and 32 percent, respectively (P = 0.02). Peripheral vascular complications necessitating surgery, blood transfusion, or both were more frequent after stenting than after balloon angioplasty (13.5 vs. 3.1 percent, P < 0.001). The mean hospital stay was significantly longer in the stent group than in the angioplasty group (8.5 vs. 3.1 days, P < 0.001). CONCLUSIONS: Over seven months of follow-up, the clinical and angiographic outcomes were better in patients who received a stent than in those who received standard coronary angioplasty. However, this benefit was achieved at the cost of a significantly higher risk of vascular complications at the access site and a longer hospital stay. [less ▲]

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See detailIntensities of the doublet-quadruplet intersystem transitions in C II and N III
Biémont, Emile ULg; Delahaye, F.; Zeippen, C. J.

in Journal of Physics : B Atomic Molecular & Optical Physics (1994), 27

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See detailBovine Leukemia Virus
Kettmann, Richard ULg; Burny, A.; Callebaut, I. et al

in The Retroviridae (1994)

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See detailOnce-a-day administration of amikacin in neonates: clinical evidence of the validity of a pharmacokinetic according to the gestational age
Battisti, Oreste ULg; Wallemacq P; Langhendries JP

in Early Human Development (1994), 38

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See detailThe Moorcock / Hawkwind Connection: Science Fiction and Rock & Roll Culture
Delville, Michel ULg

in Foundation: The Review of Science Fiction (1994)

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See detailQue retenir d’une expérience d’éducation physique quotidienne dans le cadre d’une rénovation de l’enseignement fondamental?
Piéron, Maurice; Cloes, Marc ULg; Delfosse, Catherine et al

in Revue de l'Education Physique (1994), 34(2-3), 117-120

Un projet pédagogique de l'envergure de celui qui fut mis en place dans l'enseignement fondamental de la Communauté française de Belgique exige que l'on considère les effets possibles sous de multiples ... [more ▼]

Un projet pédagogique de l'envergure de celui qui fut mis en place dans l'enseignement fondamental de la Communauté française de Belgique exige que l'on considère les effets possibles sous de multiples éclairages. Par les personnes auxquelles il s'adresse, par la diversité de ces effets et par l'organisation qu'il requiert, par la nécessité de mettre en évidence les relations de causalité, il a nécessité une méthodologie d'évaluation multidimensionnelle. [less ▲]

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See detailLa prothèse pénienne dans le traitement de l'impuissance: La décision du patient
Kempeneers, Philippe ULg; Andrianne, R.; Mormont, Christian ULg

in Cahiers de Sexologie Clinique (1994), 20(124), 31-36

In the population who look advice from our interdisciplinary team, penile prosthesis is estimated been indicated in about 13% of the cases. Among these 13% of patients to whom a penile implant was ... [more ▼]

In the population who look advice from our interdisciplinary team, penile prosthesis is estimated been indicated in about 13% of the cases. Among these 13% of patients to whom a penile implant was proposed, only 32% agreed to undergo the operation. From this statement, we wondered why some men require penile implantation and other ones resign. A follow-up survey allowed to compare the experience of 19 implants recipients to the experience of 17 patients who have refused this solution. The cost of the device appears being a very determinant argument in the decision to reject penile implantation. Our study fails to distinguls clearly the two groups of subjects on the basis of another motivation criterion. [less ▲]

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See detailAspergillose chez les oiseaux marins échoués sur la côte belge
Jauniaux, Thierry ULg; Coignoul, Freddy ULg

in Annales de Médecine Vétérinaire (1994), 138(4), 277-281

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species ... [more ▼]

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species. Debilitation and stress are favourable for the mycosis installation in captive wild birds (Zoo and rehabilitation centers). During 90-91 and 91-92 winters, 386 birds found dead at the belgian seashore were necropsied and 9 birds were carriers of specific lesions. Complementary investigations were undertaken. Most animals were oiled and had been kept for some time in rehabilitation centers. [less ▲]

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See detailA semiautomated test apparatus for studying partner preference behavior in the rat.
Bakker, Julie ULg; van Ophemert, J.; Eijskoot, F. et al

in Physiology & Behavior (1994), 56(3), 597-601

A semiautomated three-compartment box (3CB) for studying partner preference behavior of rats is described. This apparatus automatically records the rat's time spent in each compartment, as well as the ... [more ▼]

A semiautomated three-compartment box (3CB) for studying partner preference behavior of rats is described. This apparatus automatically records the rat's time spent in each compartment, as well as the locomotor activity (i.e., the number of visits an animal pays to each compartment). Software was developed for calculating partner preference scores. Behavioral testing in the semiautomated 3CB, which is a modification of an earlier version, is less time consuming and less laborious. Three 3CBs can be observed simultaneously by two trained observers, and the behavioral interactions of three experimental animals with the stimulus animals can be observed and scored by hand. The use of the new apparatus was validated by studying adult partner preference behavior of neonatally ATD-treated male rats. The collected data fully corroborate previous results, obtained in the earlier version of the 3CB, again revealing the behavioral bisexual nature of these ATD males. A new finding was the much higher locomotor activity of the ATD males compared to controls. [less ▲]

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See detailTamoxifen restores the E-cadherin function in human breast cancer MCF-7/6 cells and suppresses their invasive phenotype
Bracke, M. E.; Charlier, Corinne ULg; Bruyneel, E. A. et al

in Cancer Research (1994), 54

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See detailUse Of Bacteria Protections In Pelleting For Preinoculation Of Bean-Seeds (Phaseolus-Vulgaris L)
Jansen, Jp.; Schiffers, Bruno ULg; Mathot, P. et al

in Seed Science and Technology (1994), 22(2), 329-336

Preinoculation of bean seeds (Phaseolus vulgaris L.) with Rhibozium phaseoli material has been carried out by incorporating the inoculum in seed pelleting. An inoculum was incorporated into a mixture of ... [more ▼]

Preinoculation of bean seeds (Phaseolus vulgaris L.) with Rhibozium phaseoli material has been carried out by incorporating the inoculum in seed pelleting. An inoculum was incorporated into a mixture of vermiculite and compost or wheat bran, and applied to seeds to produce a solid pellet. The pelleted seed contained a sufficient number of bacteria per seed for effective nodulation after 56 days storage of preinoculated pelleted seeds at 25°C. Those results are not achieved using a liquid inoculum of Rhibozium. [less ▲]

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See detailL'anemie ferriprive de la grossesse.
Fraipont, V.; Beguin, Yves ULg; Fillet, Georges ULg

in Revue Médicale de Liège (1994), 49(8), 436-45

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See detailTrickle flow in packed columns : new experimental and theoretical investigations
Crine, Michel ULg; Marchot, Pierre ULg; Toye, Dominique ULg et al

in Trends in Chemical Engineering (1994), 2

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See detailAsthme et bêta2-agonistes de longue durée d'action
Bury, Thierry ULg; Kayambe, JM; Radermecker, Maurice ULg

in Médecine et Hygiène (1994), 52

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See detailCompte-rendu de l'ouvrage de Vincent de Gaulejac et d'Isabel Taboada Leonnetti: La lutte des places
Robert, Jocelyne ULg

in Revue de l'Institut de Sociologie (1994)

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See detailIGF-I and IGFBP-3 increase independently of testosterone release during the onset of puberty in cattle
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

in Growth Regulation (1994), 4(suppl 1), 116

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See detailDetection des molecules responsables de l'activite biocide des feuilles de Boscia senegalensis (Pers.) Lam ex Poir. par echantillonage d'espace de tete et spectrometrie de masse couplee a la chromatographie en phase gazeuse.
Lognay, Georges ULg; Marlier, M.; Seck, D. et al

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(1),

Des échantillons de feuilles de Boscia senegalensis (Prns.) I.ev ex Porn. ont été tnaintenus dans des conditions contrôlées sous un flux d'hélium, à l'intérieur d'une.platine de désorption thermique ... [more ▼]

Des échantillons de feuilles de Boscia senegalensis (Prns.) I.ev ex Porn. ont été tnaintenus dans des conditions contrôlées sous un flux d'hélium, à l'intérieur d'une.platine de désorption thermique directement connectée à un GC-MS. A côté du trans-2-hexénal, responsable de la note "verte" des feuilles, l'isothiocyanate de méthyle et le cyanure de méthyle (acétonitrile) ont été détectés. Ces deux produits se sont formés par dégradation enzymatique in situ d'un précurseur, la glucocapparine. Ils ont été caractérisés par leur spectre de masse. La libération de cyanure de méthyle à partir d'échantillons biologiques est expliquée. [less ▲]

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See detailMétaux lourds et isotopes stables du carbone dans la matière particulaire: distribution sur le plateau continental nord-ouest européen
Dauby, Patrick ULg; Mosora, Fiorentina; Frankignoulle, Michel et al

in Bulletin de la Société Royale des Sciences de Liège (1994), 63

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See detailHormonal profile of growing male and female diploïds and triploïds of the blue tilapia, Oreochromis aureus, reared in intensive culture
Mol, K.; Byamungu, N.; Cuisset, B. et al

in Fish Physiology and Biochemistry (1994), 13

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See detailBilateral diaphragmatic paralysis in a pony
Amory, Hélène ULg; Lomba, Fernand; Lekeux, Pierre ULg et al

in Journal of the American Veterinary Medical Association [=JAVMA] (1994), 205(4), 587-591

An adult pony had a 1-month history of severe respiratory distress that was resistant to treatment and environmental changes. Results of blood gas analysis were indicative of alveolar hypoventilation ... [more ▼]

An adult pony had a 1-month history of severe respiratory distress that was resistant to treatment and environmental changes. Results of blood gas analysis were indicative of alveolar hypoventilation. Simultaneous recordings of thoracic and abdominal wall motion by inductance plethysmography, together with complete pulmonary mechanics evaluation that included transdiaphragmatic pressure monitoring, revealed complete passive behavior of the diaphragm during breathing. Because radiography, necropsy, and histologic examination did not reveal any major lesion to explain the clinical and functional observations, bilateral diaphragmatic paralysis was diagnosed [less ▲]

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See detailAbnormal temporal patterns of glucose tolerance in obesity: relationship to sleep-related growth hormone secretion and circadian cortisol rhythmicity.
Van Cauter, E. V.; Polonsky, K. S.; Blackman, J. D. et al

in Journal of Clinical Endocrinology and Metabolism (1994), 79(6), 1797-805

To define the chronobiology of glucose tolerance and insulin secretion in obesity, nine obese men and nine lean men were studied during constant glucose infusion for 53 h, including 8 h of nocturnal sleep ... [more ▼]

To define the chronobiology of glucose tolerance and insulin secretion in obesity, nine obese men and nine lean men were studied during constant glucose infusion for 53 h, including 8 h of nocturnal sleep, 28 h of continuous wakefulness, and 8 h of daytime sleep. Blood samples were collected at 20-min intervals to assay glucose, insulin, C-peptide, cortisol, and GH. Sleep was polygraphically monitored. Abnormal temporal profiles of glucose regulation were observed during wakefulness and sleep in obese subjects. During daytime hours, the normal profile of glucose tolerance was reversed, as an improvement, rather than a deterioration, was observed from morning to late evening. This reversal of the daytime pattern appeared to be caused by a dual defect in glucose regulation during the previous night. Indeed, during early sleep, GH secretion was markedly reduced, and the nocturnal rises of glucose and insulin secretion were dampened. During late sleep, obese subjects failed to suppress insulin secretion and plasma glucose, resulting in high morning levels. Comparisons of metabolic and hormonal patterns during nocturnal and daytime sleep suggest that the failure to suppress insulin secretion in late sleep may reflect a relative insensitivity of the beta-cell to acute inhibitory effects of cortisol in addition to insulin resistance. [less ▲]

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See detailUn affranchi trop discret? : A propos des lignes 13-19 du P. Matr. Daris 2
Straus, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1994), LXIX(137), 127-131

Born of manumitted parents, Sarapion introduice himself as a freeborn though he too is a freedman. Observations on the way he got a patch of land and on the affective and sexual life of the slaves.

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See detailGreffes de moelle dans les hémoglobinopathies
Beguin, Yves ULg

in Mini Acta (1994), 26

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See detailCharacterization of an up-stream promoter directing extrapituitary expression of the human prolactin gene
Berwaer, M.; Martial, Joseph ULg; Davis, J. R.

in Molecular Endocrinology (1994), 8(5), 635-42

The human PRL gene is expressed outside pituitary lactotrophs in decidualized endometrium and lymphoid cells, but here the mRNA contains a 5'-untranslated region from an additional noncoding exon 1a. We ... [more ▼]

The human PRL gene is expressed outside pituitary lactotrophs in decidualized endometrium and lymphoid cells, but here the mRNA contains a 5'-untranslated region from an additional noncoding exon 1a. We have isolated a genomic DNA clone containing human PRL exon 1a with 2800 basepairs (bp) of 5'-flanking sequences. Sequencing locates exon 1a -5840 bp up-stream of the pituitary start site. To study its suspected regulatory function, various lengths of the 5'-flanking region were linked to the luciferase (Luc) reporter gene. Their ability to direct gene expression has been analyzed in transfection studies. The proximal 1620 bp of promoter sequence directed Luc expression in the T-lymphoid Jurkat cell line, and this was unaffected by 5'-deletion to the proximal 453 bp. However, further 5'-deletion to the most proximal 67 bp drastically reduced this activity by 90%. The exon 1a promoter was inactive in pituitary GH3 cells and HeLa cells; in contrast, the exon 1b pituitary promoter, active in GH3 cells, was inactive in Jurkat cells. DNase-I footprinting studies and further 5'- and 3'-deletion analysis identified factor-binding sites within an enhancer element located at -375/-212 bp, which contributed approximately 50% of the promoter activity. [less ▲]

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See detailInvestigation of the Western Mediterranean's hydrodynamics with the GHER three-dimensional primitive equation model
Beckers, Jean-Marie ULg; Brasseur, P.; Djenidi, Salim ULg et al

in Coastal and Estuarine Studies (1994), 46

A three-dimensional, non-linear, primitive equation model with turbulent closure developed at the GeoHydrodynamics and Environment Research Laboratory (GHER), University of Liège, is designed to define ... [more ▼]

A three-dimensional, non-linear, primitive equation model with turbulent closure developed at the GeoHydrodynamics and Environment Research Laboratory (GHER), University of Liège, is designed to define marine weather-like processes ranging from mesoscale tides and storm surges, to synoptic frontal and eddy structures, to macroscale slowly-varying currents characteristic of the so-called “general circulation”. The model is applied here to the study of the hydrodynamics of the western Mediterranean as both a metagnostic (i.e. system-oriented) model and a diagnostic (i.e. process-oriented) model with both models allowed to run simultaneously and interactively. Critical processes such as deep water formation and the instabilities of the Algerian Current, are studied to provide a basic understanding of the physics needed to adequately parameterize sub-grid scale processes in the basin wide metagnostic model. This general circulation model provides boundary conditions for the finer grid diagnostic studies as well as the general overview of the basin's hydrodynamics. Further improvement is achieved by concurrent use of a variational inverse model to provide initial data fields and boundary conditions for the direct model. In turn, the metagnostic model provides hydrodynamic constraints which are imposed to the variational principle to ensure an interpolation/extrapolation of data compatible with the system's hydrodynamics. Results viz (i) a diagnostic study of the Algerian Current, (ii) a metagnostic study of the seasonal variability of the western Mediterranean Sea, are presented and compared with observations and with results of simpler (quasi-geostrophic, reduced gravity, etc.) models. Possible improved hydrodynamic forecasts of seasonal and interannual variability with the 3D primitive equation model is discussed with particular attention to the forecast's sensitivity to initial and boundary conditions. [less ▲]

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See detailCompte rendu de Recherche de l'Ironie et ironie de la "Recherche", de P. Schoentjes
Defays, Jean-Marc ULg

in Revue Belge de Philologie et d'Histoire (1994), 72(3), 716-718

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See detailAN IMPROVED ONE-POINT INTEGRATION METHOD FOR LARGE-STRAIN ELASTOPLASTIC ANALYSIS
Stainier, Laurent ULg; Ponthot, Jean-Philippe ULg

in Computer Methods in Applied Mechanics & Engineering (1994), 118(1-2), 163-177

In this paper, we present a new one-point integration method generalizing Flanagan and Belytschko's method (Internat. J. Numer. Methods Engrg. 17 (1981) 679-706) and a modification of Belytschko and ... [more ▼]

In this paper, we present a new one-point integration method generalizing Flanagan and Belytschko's method (Internat. J. Numer. Methods Engrg. 17 (1981) 679-706) and a modification of Belytschko and Bindeman's method (Comput. Methods Appl. Mech. Engrg. 88 (1991) 311-340), both in the frame of large deformation elastoplastic analysis. These stabilization methods are combined with the radial return method used to integrate the constitutive law. Plane strain problems are first considered, and the method is then generalized to axisymmetrical situations. The explicit time integration scheme with its critical timestep is also considered. A few examples are presented that show the great time savings that can be obtained with reduced integration without any loss of accuracy, and even with a gain in the solution quality, since the underintegrated elements prove to be 'flexurally superconvergent'. [less ▲]

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See detailSynthesis and biodistribution of [5-131I]iodotropapride: a potential D2 dopamine receptor imaging agent.
Cantineau, Robert; Guillaume, Marcel; Damhaut, Philippe et al

in Nuclear Medicine & Biology (1994), 21(2), 255-62

[5-131I]Iodotropapride is a benzamidic compound which displays high affinity and selectivity for dopaminergic receptors. It was prepared from the corresponding brominated compound by a nucleophilic ... [more ▼]

[5-131I]Iodotropapride is a benzamidic compound which displays high affinity and selectivity for dopaminergic receptors. It was prepared from the corresponding brominated compound by a nucleophilic substitution with [131I]iodine (t1/2 = 8.02 days, E gamma = 364 keV) based on the use of Cu(I) as catalyst and high specific activity of [131I]NaI. After i.v. injection in rats the tracer crosses the blood-brain barrier (0.42 +/- 0.06% of injected dose in the total brain) and demonstrates a high affinity binding to the striatum. The striatum-to-cerebellum ratio increases with time and reaches values of 9 and 22 at 30 and 120 min after injection, respectively. This specific uptake in the striatum is saturable and can be blocked by pretreatment with different D2 antagonists. When labeled with 123I (t1/2 = 13 h, E1 = 159 keV), the corresponding [123I]iodotropapride may be useful for the investigation of the D2 dopamine receptors in humans with single photon emission computer tomography (SPECT). [less ▲]

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See detailL'inventaire forestier wallon: un outil de developpement regional
Rondeux, Jacques ULg

in Wallonie (1994), 21(34), 3-8

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See detailSymbolic Verification with Periodic Sets
Boigelot, Bernard ULg; Wolper, Pierre ULg

in Lecture Notes in Computer Science (1994), 818

Symbolic approaches attack the state explosion problem by introducing implicit representations that allow the simultaneous manipulation of large sets of states. The most commonly used representation in ... [more ▼]

Symbolic approaches attack the state explosion problem by introducing implicit representations that allow the simultaneous manipulation of large sets of states. The most commonly used representation in this context is the Binary Decision Diagram (BDD). This paper takes the point of view that other structures than BDD's can be useful for representing sets of values, and that combining implicit and explicit representations can be fruitful. It introduces a representation of complex periodic sets of integer values, shows how this representation can be manipulated, and describes its application to the state-space exploration of protocols. Preliminary experimental results indicate that the method can dramatically reduce the resources required for state-space exploration. [less ▲]

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See detailPump up the volume! Mogelijkheid en onmogelijkheid van het manifest in postmoderne tijden
Spinoy, Erik ULg

in De Zingende Zaag (1994), (24-25), 102-123

This article reflects on the fact that manifests are a predominantly modernist genre. In postmodern times, manifests can only reappear as simulations or parodies.

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See detailDinant/Anseremme: Trou Magrite
Noiret, Pierre ULg

in Chronique de l'Archéologie wallonne (1994), 2

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See detailLe financement au niveau communal
Jurion, Bernard ULg

in Mouvement communal, Union des Villes et des Communes de Belgique (1994)

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See detailChloride and Inorganic Phosphate Modulate Binding of Oxygen to Bovine Red Blood Cells
Gustin, Pascal ULg; Detry, Benoît; Cao, M. L. et al

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1994), 77(1), 202-208

The influence of Pi and Cl on the equilibrium of oxygen binding to bovine red blood cells was assessed by plotting the whole blood oxygen dissociation curve measured under standard conditions with and ... [more ▼]

The influence of Pi and Cl on the equilibrium of oxygen binding to bovine red blood cells was assessed by plotting the whole blood oxygen dissociation curve measured under standard conditions with and without added KCl and K2HPO4. Both salts shifted the oxygen dissociation curve to the right. This effect was more marked at the highest saturation levels. At a given saturation level, the anion-induced shift was linearly related to the concentration of salt added to the blood. Cl had a greater effect than Pi. The relationship between changes in Po2 at 50% hemoglobin saturation (in Torr) and concentrations of ions added (in mmol/l) was equal to 0.0515[Cl] + 0.0302[Pi] (r2 = 0.94; P < 0.001). These changes were not due to the hyperosmolality induced by salt addition, since sucrose added in place of salts was without effect on the measured parameters. The oxygen exchange fraction expressed as percentage of saturation, i.e., the difference in hemoglobin saturation when Po2 decreases from 130 to 40 Torr, was linearly correlated to added anion concentration (in mmol/l) (= 0.102[Cl] + 0.059[Pi] (r2 = 0.95; P < 0.001)). No significant interaction between the anions was observed; their effects were purely additive. This original mechanism of controlling the oxygen affinity of bovine blood may have clinical relevance: Cl and Pi could be used to increase oxygen transport efficiency in hypoxic animals [less ▲]

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See detailRecherches paléolithiques et mésolithiques en Belgique, 1993: le Trou Magrite, Huccorgne et l'Abri du Pape
Noiret, Pierre ULg; Otte, Marcel ULg; Straus, Lawrence et al

in Notae Praehistoricae (1994), 13

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See detailINTERNATIONAL-CONFERENCE ON BARBUS - PRESENT AND FUTURE - FOREWORD
BERREBI, P.; Poncin, Pascal ULg

in Bulletin Francais De La Peche Et De La Pisciculture (1994), (334), 167-168

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See detailConstruction d'un modèle de répartition des arbres par classes de grosseur pour des plantations d'épicéa commun (Picea abies L Karst) en Ardenne belge
Lejeune, Philippe ULg

in Annales des Sciences Forestières (1994), 51(1), 53-65

The construction of a girth distribution model for Norway spruce (Picea abies L Karst) plantations has been considered using 141 sample plots of 1 000 m². The effects of the theoretical distribution ... [more ▼]

The construction of a girth distribution model for Norway spruce (Picea abies L Karst) plantations has been considered using 141 sample plots of 1 000 m². The effects of the theoretical distribution (comparison of the normal and Weibull distributions) and the estimation methods have been analysed. Despite the higher flexibility of the Weibull distribution, its use does not lead to a more accurate prediction of the distribution. The small number of samples measured in the plots seems to be the primary cause of the inaccuracy of the various models. Considering the data analysed, the normal distribution, which is easier to use, is proving to be more suitable for the creation of distribution model for such stands. [less ▲]

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See detailLe Paléolithique supérieur de Moldavie. Recherches récentes
Noiret, Pierre ULg; López Bayón, Ignacio

in Bulletin de l'Association scientifique liégeoise pour la Recherche archéologique (1994), XXI

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See detailModélisation mathématique appliquée à la délimitation des zones de protection: cas du site de captage de Vivegnis (plaine alluviale de la Meuse, Belgique)
Derouane, Johan; Dassargues, Alain ULg

in Bulletin du Centre d'Hydrogéologie de l'Université de Neuchätel (Suisse) (1994), 13

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See detailVariations of lyoluminescence with commercial origin of the dosimeters
Galand, Eric; Niezette, Jacques; Vanderschuren, Jacques et al

in Radiation Physics and Chemistry (1994), 43

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See detailGéologie de la région de Puagne, Bande de Sambre-et-Meuse (Belgique). Hypothèses basées sur l'état de maturation des palynomorphes fossiles
Steemans, Philippe ULg

in Comptes Rendus de l'Académie des Sciences. Série 2, Sciences de la Terre et des Planètes (1994), 318(11), 1551-1556

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See detailSynthesis of barium-titanate by the sol-gel process
LEMOINE, Christine; Gilbert, Bernard ULg; MICHAUX, Bernard et al

in Journal of Non-Crystalline Solids (1994), 175(1), 1-13

Homogeneous BaTiO3 gels were prepared by hydrolysis and polycondensation reactions between titanium isopropoxide and barium hydroxide in the presence of methoxyethanol, methanol and water. Gel formation ... [more ▼]

Homogeneous BaTiO3 gels were prepared by hydrolysis and polycondensation reactions between titanium isopropoxide and barium hydroxide in the presence of methoxyethanol, methanol and water. Gel formation mechanisms were investigated by Raman scattering spectrometry. Two drying methods are carried out: either in air with a possible formation of barium carbonate or in a vacuum furnace, sheltered from CO2. The influence of the drying method on texture is studied through nitrogen adsorption-desorption isotherm analyses. A heat treatment is deduced from thermogravimetry and differential scanning calorimetry results. The influence of the calcining temperature on the texture and the crystallization of the solids has been measured. For the first time, the transformation at 900 degrees C from the cubic to the tetragonal form of BaTiO3 has been observed by polarization microscopy. [less ▲]

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See detailON THE FUNCTIONAL-CHARACTERIZATION OF THE ANALYTIC WAVE-FRONT SET OF AN HYPERFUNCTION
Bastin, Françoise ULg; LAUBIN, P.

in Mathematische Nachrichten (1994), 166

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See detailThe treatment of amiodarone-induced hyperthyroidism. Is there a place for surgery?
Meurisse, Michel ULg; Detroz, Bernard ULg; Messens, D. et al

in Acta Chirurgica Belgica (1994), 94(1), 36-41

In many instances amiodarone-induced hyperthyroidism has been reported as mild, thyroid functions returning to normal after discontinuation of the drug. Nevertheless, life-threatening amiodarone-induced ... [more ▼]

In many instances amiodarone-induced hyperthyroidism has been reported as mild, thyroid functions returning to normal after discontinuation of the drug. Nevertheless, life-threatening amiodarone-induced thyrotoxicosis has also been described. Conventional treatments such as with antithyroid drugs (Thionamide) and corticosteroids are essentially ineffective or fail to stop the dramatic course of the thyroid crisis. This limited efficacy of medical therapy, particularly in patients with previously--neglected or unknown--thyroid disease, prompted us to intervene surgically. We report a series of six patients who underwent total or nearly total thyroidectomy as first line therapy for four of them. Surgery resulted in rapid resolution of thyrotoxicosis with an uneventful postoperative course. This approach has the advantage of immediate and safe efficacy, low risk of relapse and finally, appears to be the only antithyroid treatment that permits continued therapy with amiodarone. [less ▲]

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See detailThe Perturbed Tikhonov's Algorithm and Some of its Applications
Tossings, Patricia ULg

in RAIRO : Modélisation Mathématique et Analyse Numérique (Mathematical Modelling and Numerical Analysis) (1994), 28(2), 189-221

The proximal point algorithm has known these last years many developments connected with the expansion of the variational convergence theory. Motivated by this fact and inspired by the work of A. Tikhonov ... [more ▼]

The proximal point algorithm has known these last years many developments connected with the expansion of the variational convergence theory. Motivated by this fact and inspired by the work of A. Tikhonov and V. Arsénine in the context of convex optimization, we present a new algorithm for searching a zero of a maximal monotone operator on a real Hilbert space. We study the perturbed version of this algorithm and establish a critical comparison with the perturbed proximal point algorithm. We apply this new algorithm to convex optimization and to variational inclusions or, more particularly, to variational inequalities. [less ▲]

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See detailComparison of Reproductive Performance in Belgian Dairy and Beef Cattle
Hanzen, Christian ULg; Laurent, Y.; Ward, W. R.

in Theriogenology (1994), 41(5), 1099-114

A computerized program was written to collect, evaluate and compare reproductive performance data of 2004 beef (Belgian Blue breed) and 1649 dairy (Friesian Holstein and German Red) cattle in 35 Belgian ... [more ▼]

A computerized program was written to collect, evaluate and compare reproductive performance data of 2004 beef (Belgian Blue breed) and 1649 dairy (Friesian Holstein and German Red) cattle in 35 Belgian herds (6 suckler beef herds, 9 milked beef herds and 20 dairy herds). Reproduction data were collected at monthly herd health visits. No difference in age at first calving was observed. Significant differences were observed among the 3 kinds of herds, and the best results were obtained in dairy herds for the calving interval, interval from calving to the first estrus, interval from calving to the first service and average number of days open. Concerning these parameters, first calvers had lower results than multiparous cows, mainly in suckler and milked beef herds. Significant differences were noted in the number of services per pregnancy. Heifers that had never calved presented the highest fertility. Primiparous beef cows had higher fertility than pluriparous cows. In dairy herds, pluriparous cows had higher fertility than primiparous cows. Estrus detection was better in milked beef herds than in suckled beef and dairy herds. Suckled beef herds had the lowest incidence of metritis and ovarian cysts of the three types of herds. Rates of abortion, overall culling and retained fetal membranes were similar in all the herds. The percentage of animals removed for infertility was highest in milked beef herds and lowest in dairy herds. Because 90% of the 1159 calvings recorded in the beef herds required a caesarean section, the reproductive performance of beef cattle represent results after caesarean section. [less ▲]

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See detailRestriction fragment length polymorphisms in cattle
Falaki, Mohammed; Renaville, Robert ULg; Sneyers, Myriam et al

in Journal of Animal Science (1994), 72(suppl 1), 316

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See detailSignificance of soluble transferrin receptor
Beguin, Yves ULg; Loo, M.; R'Zik, Samir ULg et al

in Molecular Biology of Hematopoiesis (1994)

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See detailLa régionalisation du droit pénal international
Flore, Daniel ULg; Thomas, F.

in Revue internationale de droit pénal (1994)

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See detailModèles de cubage pour essences multi-tiges : application à des plantations d'acacia
Lejeune, Philippe ULg; Rondeux, Jacques ULg

in Cahiers Agricultures (1994), 3(3), 189-194

Tree-volume equations were devised to estimate the volume of wood (excluding bark) of Acacia auriculiformis A. Cunn ex Benth fuelwood plantations in Zaïre. The tables give the total volume of stems and ... [more ▼]

Tree-volume equations were devised to estimate the volume of wood (excluding bark) of Acacia auriculiformis A. Cunn ex Benth fuelwood plantations in Zaïre. The tables give the total volume of stems and branches to an upper girth limit of 9 cm, together with the volumes according to the following classes of girth : 9-14, 15-44 and over 45 cm. Because this species has a high proportion of multiple-stem trees (which begin forking below the breast-height level), girth at 1.30 m is a relatively meaningless concept. Taking the extent of this variable in tree volume estimation into account, various expressions of girth were investigated. Instead of considering each stem girth individually, a "standardised" girth at 1.30 m (from ground level) was adopted. For any given tree, this corresponds to the quadratic sum of all girths measured at 1,30 m. [less ▲]

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See detailMeaningful Interiors: An Interview with Clark Coolidge
Delville, Michel ULg

in BELL. Belgian Essays on Language and Literature (1994)

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See detailRelationship between alpha 2-adrenergic function and suicidal behavior in depressed patients.
Pitchot, William ULg; Ansseau, Marc ULg; Gonzalez Moreno, A. et al

in Psychiatry Research (1994), 52(2), 115-23

The current main neurochemical theories of the biological correlates of suicidal behavior involve serotonergic and, to a lesser extent, dopaminergic systems. Few data are available about the possible ... [more ▼]

The current main neurochemical theories of the biological correlates of suicidal behavior involve serotonergic and, to a lesser extent, dopaminergic systems. Few data are available about the possible implication of the noradrenergic function. In the present study, we assessed the growth hormone response to clonidine, a selective alpha 2-adrenergic agonist, in 15 DSM-III-R major depressive inpatients with a history of suicide attempts, compared with 15 age- and gender-matched major depressive inpatients without a history of suicidal behavior. Mean (+/- SD) growth hormone peak responses to clonidine were significantly lower in the group of suicide attempters than in the control group: 2.93 +/- 3.01 ng/ml vs. 8.28 +/- 8.15 ng/ml. Therefore, these results suggest that a blunted growth hormone response to clonidine could be a biological correlate of suicidal behavior. [less ▲]

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See detailCritical appraisal of pressure-frequency relation for estimation of diaphragm function in intact and conscious animals
Desmecht, Daniel ULg; Linden, Annick ULg; Lekeux, Pierre ULg

in American Journal of Veterinary Research (1994), 55(12), 1638-1646

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See detailDe réels progrès ont-ils été faits dans le traitement de l'ostéoporose ?
Reginster, Jean-Yves ULg; DEROISY, Rita ULg; Franchimont, P

in Les Nouvelles de Rhumatologie (1994), 4

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See detailDinant/Falmignoul: Abri du Pape
Noiret, Pierre ULg

in Chronique de l'Archéologie wallonne (1994), 2

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See detailPopulation dynamics of CD4+ T cells lacking Thy-1 in murine retrovirus-induced immunodeficiency syndrome (MAIDS).
Moutschen, Michel ULg; Colombi, S.; Deprez, Manuel ULg et al

in Scandinavian Journal of Immunology (1994), 39(2), 216-24

Increased numbers of CD4+ Thy-1- cells have been described in the spleen (SP) of mice with retrovirus-induced immunodeficiency (MAIDS). Since this phenotypic abnormality might have considerable functional ... [more ▼]

Increased numbers of CD4+ Thy-1- cells have been described in the spleen (SP) of mice with retrovirus-induced immunodeficiency (MAIDS). Since this phenotypic abnormality might have considerable functional importance, the expansion of the CD4+ Thy-1- subset in MAIDS was characterized further. CD4+ Thy-1- and Thy-1+ T-cells from infected mice expressed similar densities of CD3 and TCR alpha/beta. In contrast, the Thy-1- subset was uniformly CD44hi, even early in the disease when part of Thy-1+ cells were still CD44lo. The emergence of CD4+ Thy-1- cells occurred first in SP and lymph nodes and was observed later in thymus. The important fraction of CD4+ cells lacking Thy-1 normally present in Peyer's patches was only weakly modified. Despite the major expansion of the CD4+ Thy-1- phenotype, the proliferating fraction was not higher in this subset than in CD4+ Thy-1+ cells from infected mice. Persistence after hydroxyurea administration was identical in both subsets, indicating similar mean cell lifespans. Taken together, these results show that the major expansion of CD4+ Thy-1- T-cells in MAIDS is not ascribable solely to increased proliferation within this subset. Phenotypic analysis suggests that CD4+ Thy-1- cells result from the differentiation of Thy-1+ cells induced by activation signals related to retroviral infection. [less ▲]

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See detailCationic and secretory effects of BPDZ 44 and diazoxide in rat pancreatic islets
Antoine, M.-H.; Pirotte, Bernard ULg; Hermann, M. et al

in Experientia (1994), 50

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See detailSuccessful removal of an intramedullary spinal paraganglioma from a dog
Poncelet, Luc; Snaps, Frédéric ULg; Jacobovitz, D. et al

in Journal of the American Animal Hospital Association (1994), 30(3), 213-216

An 11-year-old, mixed-breed dog suffering progressive asymmetric hind limb ataxia was diagnosed as having spinal cord compression at the L1 spinal level. An intramedullary, encapsulated tumor was ... [more ▼]

An 11-year-old, mixed-breed dog suffering progressive asymmetric hind limb ataxia was diagnosed as having spinal cord compression at the L1 spinal level. An intramedullary, encapsulated tumor was surgically removed. Tumor microscopic features, positive neuron-specific enolase (NSE) immunostaining, and Grimelius staining led to the diagnosis of paraganglioma. The dog was free from any neuroloaic signs 12 days after surgery. [less ▲]

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