References of "Scientific journals"
     in
Bookmark and Share    
Peer Reviewed
See detailMolecular bases of the interaction between human prolactin and its membrane receptor: A ten year study
KINET, Sandrina; BERNICHTEIN, Sophie; LLOVERA, Marta et al

in Recent research developments in endocrinology (2001), 2

In this review, we make a chronologically overview of a project aimed at deciphering the molecular bases of the mechanism by which prolactin, a pituitary-secreted polypeptidic hormone, interacts with its ... [more ▼]

In this review, we make a chronologically overview of a project aimed at deciphering the molecular bases of the mechanism by which prolactin, a pituitary-secreted polypeptidic hormone, interacts with its membrane receptor, a member of the cytokine receptor superfamily. This study, based essentially on structural and mutational analysis of human prolactin, has identified two regions interacting with the receptor, named binding sites 1 and 2. We have also provided evidence that prolactin induces dimerization of its receptor through its two binding sites, and based on that mechanism of activation, we have engineered and characterized prolactin antagonists able to block the effect of the hormone by competition for receptor binding. Our study has also highlighted the importance of using well characterized bioassays to monitor such a structure-function study since the properties of a given hormone analog were shown to strongly differ depending on the bioassay used. [less ▲]

Detailed reference viewed: 47 (4 ULg)
Full Text
Peer Reviewed
See detailUretere retrocave chez un enfant de dix ans.
Kakanou, A.; NCHIMI LONGANG, Alain ULg; Ghuysen, M. S. et al

in Annales de Chirurgie (2001), 126(2), 156-8

Retrocaval ureter is an uncommon abnormality of the inferior vena cava, which is rarely detected in the child due to its non-specific symptomatology. Despite a varying state of severity, chronic ureteral ... [more ▼]

Retrocaval ureter is an uncommon abnormality of the inferior vena cava, which is rarely detected in the child due to its non-specific symptomatology. Despite a varying state of severity, chronic ureteral obstruction generally leads to the deterioration of renal function during adulthood. Treatment depends on the symptomatology in question, and surgical management should be as conservative as possible. [less ▲]

Detailed reference viewed: 15 (5 ULg)
See detailLe Romuleon en françois, traduction de Sébastien Mamerot.
Moreno, Paola ULg

in Revue Belge de Philologie et d'Histoire (2001)

Detailed reference viewed: 19 (4 ULg)
Full Text
See detailQuelques spécimens exceptionnels de premières plantes terrestres découvertes au Brésil (Bassin du Paraná, Dévonien basal)
Gerrienne, Philippe ULg; Milagres, I.; Bergamaschi, S. et al

in Geo-Eco-Trop (2001), 25

Detailed reference viewed: 34 (11 ULg)
Peer Reviewed
See detailL’administration publique et les technologies de l’information
Cornet, Annie ULg; Rondeaux, Giseline ULg

in Gestion : Revue Internationale de Gestion (2001), 26(1), 28-30

Detailed reference viewed: 64 (1 ULg)
Full Text
Peer Reviewed
See detailLarge pion pole in Z(S)(MOM)/(Z(P)(MOM) from Wilson action data
Cudell, Jean-René ULg; Le Yaouanc, A.; Pittori, C.

in Physics Letters B (2001), 516(1-2), 92-102

Detailed reference viewed: 16 (4 ULg)
Peer Reviewed
See detailAvancées récentes en biologie moléculaire du virus de la diarrhée virale bovine
Dehan, Pierre ULg; Hamers, C.; Couvreur, B. et al

in Annales de Médecine Vétérinaire (2001), 145

Detailed reference viewed: 22 (6 ULg)
Peer Reviewed
See detailDégradation de dalles de tablier de ponts en Belgique. Etude d'une pathologie complexe
Demars, Philippe; Gilles, Pierre; Darimont, Anne ULg

in Bulletin des Laboratoires des Ponts et Chaussées (2001), 232

Detailed reference viewed: 96 (2 ULg)
Full Text
See detailProgramme international pour le suivi des acquis des élèves (PISA) de l'OCDE
Lafontaine, Dominique ULg; Baye, Ariane ULg; Matoul, Anne ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), 7-8(7-8), 53-57

Detailed reference viewed: 57 (10 ULg)
Full Text
Peer Reviewed
See detailImproved pulmonary adaptation in newborn calves with postnatal acidosis
Varga, J.; Mester, L.; Borzsonyi, L. et al

in Veterinary Journal (2001), 162

The adaptation of newborn calves to extra-uterine life was evaluated by measuring arterial blood gases, acidÐbase values, blood ions and lung mechanical function parameters in normal and acidotic calves ... [more ▼]

The adaptation of newborn calves to extra-uterine life was evaluated by measuring arterial blood gases, acidÐbase values, blood ions and lung mechanical function parameters in normal and acidotic calves during the first 24 h. Twenty-seven Holstein Friesian newborn calves were divided into two groups according to their immediate post partum arterial blood pH values (Group A blood pH ≥ 7.2: normal group; Group B blood pH between 7.2 and 7.0: acidotic group). Pulmonary function parameters were measured and arterial blood samples were analysed for blood gases, acidÐbase variables and ion content immediately post partum (within 2 min) and then 6 and 24 h after calving. Lung resistance and maximal difference between pressure maximum and pressure minimum (maxδPpl) decreased, while dynamic lung compliance increased significantly in both groups. Immediately post partum the lung resistance and maxδPpl were significantly higher in the acidotic group than in the normal group. The arterial blood pH progressively compensated with time in both groups during the first 24 h and there was no difference in arterial blood pH values between the two groups 6 h after birth. These results showed that the compensation of acidosis was associated with the improvement in lung mechanics and these changes occurred mainly during the first 6 h of life. Moderate to pronounced acidosis did not affect the pulmonary adaptation negatively, although some respiratory mechanics parameters (maxδPpl), blood pH and Ca2+ion concentrations remained significantly different between the normal and acidotic groups at 24 h. This might be the result of overcompensation of acidosis and the interdependence between blood pH and Ca2+concentrations. [less ▲]

Detailed reference viewed: 44 (4 ULg)
Full Text
Peer Reviewed
See detailChanges in polyamines, auxins and peroxidase activity during in vitro rooting of Fraxinus angustifolia shoots: an auxin-independent rooting model
Tonon, Giustino; Kevers, Claire ULg; Gaspar, Thomas ULg

in Tree Physiology (2001), 21(10), 655-663

Among shoots of Fraxinus angustifolia Vahl raised in vitro, 76% rooted after culture on root induction medium for 5 days in darkness followed by culture on root expression medium for 15 days in light. The ... [more ▼]

Among shoots of Fraxinus angustifolia Vahl raised in vitro, 76% rooted after culture on root induction medium for 5 days in darkness followed by culture on root expression medium for 15 days in light. The addition of 20.7 muM indole-butyric acid (IBA) to the root induction medium did not significantly increase the rooting percentage (88%). Putrescine, spermidine, cyclohexylamine (CHA) and aminoguanidine (AG) enhanced rooting up to 100% (98.66% for AG), when applied during root induction in the absence of IBA, otherwise these compounds inhibited rooting, as did spermine and difluoromethylornithine (DFMO) + difluoromethylarginine (DFMA). The root induction phase was characterized by a temporary increase in endogenous free indole-acetic acid (IAA) and putrescine concentrations during root induction, whereas the root expression phase was characterized by increased peroxidase activity and low concentrations of polyamines. These changes were specifically associated with the rooting process and did not depend on the presence of exogenous IBA, because application of exogenous IBA enhanced the amount of IAA in the cuttings but did not affect rooting or the pattern of changes in polyamines and peroxidase. The effects of CHA, AG and DFMO + DFMA on endogenous concentrations of auxins and polyamines highlight the close relationship between the effects of IAA and putrescine in root induction and suggest that polyamine catabolism has an important role in root formation and elongation. [less ▲]

Detailed reference viewed: 37 (7 ULg)
Full Text
Peer Reviewed
See detailAntimicrobial susceptilities of Campylobacter strains isolated from food animals in Belgium.
Van Looveren, M.; Daube, Georges ULg; De Zutter, L. et al

in Journal of Antimicrobial Chemotherapy (2001), 48

Afin d’assurer une transparence tout le long de la chaîne de transformation de la viande, il faut disposer d’un système de traçabilité performant. La traçabilité administative montre des limites que ... [more ▼]

Afin d’assurer une transparence tout le long de la chaîne de transformation de la viande, il faut disposer d’un système de traçabilité performant. La traçabilité administative montre des limites que l’utilisation de marqueurs génétiques pourrait surmonter. Le génome de chaque individu possède des différences de séquences, à la base du polymorphisme génétique, dont les marqueurs génétiques sont les témoins. Parmi ceux-ci, deux classes semblent s’imposer en matière de traçabilité : les microsatellites et les polymorphismes simple nucléotide. Les microsatellites sont caractérisés par un degré de polymorphisme important avec de nombreux allèles pour un même locus. De plus, leur détection se fait directement par amplification itérative. Techniquement, le problème se pose lors de la détection simultanée de plusieurs microsatellites où le patron obtenu est difficile à interpréter. Les polymorphismes simple nucléotide sont répresentés par des mutations ponctuelles dans la séquence nucléotidique. Ils sont fréquents, stables, répartis de façon aléatoire et généralement bialléliques. La détection se fait soit par hybridation sur des biopuces, soit par spectrométrie de masse ou par d’autres techniques facilement automatisables. Cette automatisation est nécessaire pour pouvoir tester un grand nombre de polymorphismes simultanément sur un grand nombre d’échantillons, permettant ainsi de diminuer les coûts. L’avantage majeur des polymophismes simple nucléotide est le signal binaire obtenu, son désavantage est le caractère population- spécifique de ce type de marqueur. [less ▲]

Detailed reference viewed: 24 (2 ULg)
Full Text
See detailGénéralisation de l'apprentissage d'une langue moderne à l'école primaire ; première analyse de la situation
Straeten, M.; Blondin, Christiane ULg

in Point sur la Recherche en Education (Le) (2001), 19

Detailed reference viewed: 45 (0 ULg)
Full Text
Peer Reviewed
See detailObligations des parties et sanctions des obligations dans la Convention de Vienne
Wautelet, Patrick ULg; van Houtte, Hans

in Revue du droit des affaires internationales - International Business Law Journal (2001)

This paper provides a detailed overview of the rights and duties of both seller and buyer under the Vienna Sales Convention. It does so in the light not only of the text of the Convention but also of the ... [more ▼]

This paper provides a detailed overview of the rights and duties of both seller and buyer under the Vienna Sales Convention. It does so in the light not only of the text of the Convention but also of the emerging case law of various countries, which is reviewed and taken into account. The overview also attempts to contrast the rules of the Convention with the rules applicable in Belgian contract law. [less ▲]

Detailed reference viewed: 185 (3 ULg)
Peer Reviewed
See detailPossibili correlazioni tra riscontri neurofisiologici e genetica molecolare nell'emicrania
Ambrosini, A.; Schoenen, Jean ULg

in Confinia Cephalalgica (2001), 10

Detailed reference viewed: 20 (0 ULg)
Full Text
Peer Reviewed
See detailThe Pyoverdin Of Pseudomonas Fluorescens Btp2, A Novel Structural Type
Ongena, MARC ULg; Jacques, Philippe ULg; Thonart, Philippe ULg et al

in Tetrahedron Letters (2001), 42(34),

Abstract—From Pseudomonas fluorescens BTP2 a pyoverdin was isolated which contained the so far not encountered Val in its peptide chain. Its structure could be elucidated by chemical degradation and ... [more ▼]

Abstract—From Pseudomonas fluorescens BTP2 a pyoverdin was isolated which contained the so far not encountered Val in its peptide chain. Its structure could be elucidated by chemical degradation and spectroscopic data. [less ▲]

Detailed reference viewed: 70 (1 ULg)
See detailLe point sur le dépérissement de l’aulne
Claessens, Hugues ULg; Cavelier, Marc

in Forêt Wallonne (2001), 49/50

Detailed reference viewed: 17 (4 ULg)
Full Text
Peer Reviewed
See detailLe point sur la transplantation pancreatique.
De Roover, Arnaud ULg; Detry, Olivier ULg; Hamoir, Etienne ULg et al

in Revue Médicale de Liège (2001), 56(8), 557-62

Pancreas transplantation significantly improves the quality of life as well as the survival of the diabetic patient. It is also associated with stabilization and reversal of secondary diabetic ... [more ▼]

Pancreas transplantation significantly improves the quality of life as well as the survival of the diabetic patient. It is also associated with stabilization and reversal of secondary diabetic complications. Improvements in organ preservation, surgical techniques and immunosuppression have achieved one-year graft survival of more than 90% for combined kidney-pancreas transplant and 80% for isolated pancreas transplantation. Recipient evaluation must weigh the benefits of the procedure with the risk associated with surgery and chronic immunosuppression. Combined kidney-pancreas transplantation appears today as the best treatment for the diabetic patient with end stage renal disease. Isolated pancreas transplantation is reserved to non-uremic patients with severe diabetic complications or with brittle glycaemic control and severe impairment of quality of life. [less ▲]

Detailed reference viewed: 74 (9 ULg)
Full Text
Peer Reviewed
See detailPDX:PBX complexes are required for normal proliferation of pancreatic cells during development.
Dutta, S.; Gannon, M.; Peers, Bernard ULg et al

in Proceedings of the National Academy of Sciences of the United States of America (2001), 98(3), 1065-70

The homeobox factor PDX-1 is a key regulator of pancreatic morphogenesis and glucose homeostasis; targeted disruption of the PDX-1 gene leads to pancreatic agenesis in pdx-1(-/-) homozygotes. Pdx-1 ... [more ▼]

The homeobox factor PDX-1 is a key regulator of pancreatic morphogenesis and glucose homeostasis; targeted disruption of the PDX-1 gene leads to pancreatic agenesis in pdx-1(-/-) homozygotes. Pdx-1 heterozygotes develop normally, but they display glucose intolerance in adulthood. Like certain other homeobox proteins, PDX-1 contains a consensus FPWMK motif that promotes heterodimer formation with the ubiquitous homeodomain protein PBX. To evaluate the importance of PDX-1:PBX complexes in pancreatic morphogenesis and glucose homeostasis, we expressed either wild-type or PBX interaction defective PDX-1 transgenes under control of the PDX-1 promoter. Both wild-type and mutant PDX-1 transgenes corrected glucose intolerance in pdx-1 heterozygotes. The wild-type PDX-1 transgene rescued the development of all pancreatic lineages in pdx-1(-/-) animals, and these mice survived to adulthood. In contrast, pancreata from pdx-1(-/-) mice expressing the mutant PDX-1 transgene were hypoplastic, and these mice died within 3 weeks of birth from pancreatic insufficiency. All pancreatic cell types were observed in pdx-1(-/-) mice expressing the mutant PDX-1 transgene; but the islets were smaller, and increased numbers of islet hormone-positive cells were noted within the ductal epithelium. These results indicate that PDX-1:PBX complexes are dispensable for glucose homeostasis and for differentiation of stem cells into ductal, endocrine, and acinar lineages; but they are essential for expansion of these populations during development. [less ▲]

Detailed reference viewed: 23 (2 ULg)
Full Text
Peer Reviewed
See detailThe Homolytic And Heterolytic Fatty Acid Hydroperoxide Lyase-Like Activities Of Hematin
Delcarte, J.; Jacques, Philippe ULg; Fauconnier, Marie-Laure ULg et al

in Biochemical and Biophysical Research Communications (2001), 286(1),

Pentenols and pentene dimers are biosynthetized in plants by homolytic fatty acid hydroperoxide lyase (HPL) or HPL-like enzymes. It has been found that these compounds can modify the flavor of olive oil ... [more ▼]

Pentenols and pentene dimers are biosynthetized in plants by homolytic fatty acid hydroperoxide lyase (HPL) or HPL-like enzymes. It has been found that these compounds can modify the flavor of olive oil. Reactions between hematin and 13-hydroperoxyoctadecatrienoic acid resulted in the formation of the same compounds via a free radical reaction in which an alkoxyl radical derived from linolenic acid hydroperoxide undergoes a β-scission. (Z)-3-Hexenal has also been detected as a minor product of the reaction. It is bioconversed from the same substrate in plants by heterolytic HPL. Thanks to the redox cycle of its central iron, hematin has both homolytic and heterolytic HPL-like activities. [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailRésumé C.E. n°89.185, du 31 juillet 2000, Van Den Borre
Delnoy, Michel ULg

in Aménagement - Environnement (2001), 1

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailL'autonomie fiscale des communautés et des régions après les accords du Lambermont
Bourgeois, Marc ULg

in Actualités du Droit (2001)

Detailed reference viewed: 52 (10 ULg)
Full Text
Peer Reviewed
See detailResonance-assisted tunneling in near-integrable systems
Brodier, O.; Schlagheck, Peter ULg; Ullmo, D.

in Physical Review Letters (2001), 87(6), 064101

Dynamical tunneling between symmetry related invariant tori is studied in the near-integrable regime. Using the kicked Harper model as an illustration, we show that the exponential decay of the wave ... [more ▼]

Dynamical tunneling between symmetry related invariant tori is studied in the near-integrable regime. Using the kicked Harper model as an illustration, we show that the exponential decay of the wave functions in the classically forbidden region is modified due to coupling processes that are mediated by classical resonances. This mechanism leads to a substantial deviation of the splitting between quasidegenerate eigenvalues from the purely exponential decrease with 1/(h) over bar obtained for the integrable system. A simple semiclassical framework, which takes into account the effect of the resonance substructure on the invariant tori, allows one to quantitatively reproduce the behavior of the eigenvalue splittings. [less ▲]

Detailed reference viewed: 18 (0 ULg)
Full Text
See detailLes flux d'azote mobilisés par les agricultures belges
Debouche, Charles ULg

in Bulletin d'Information (Association Royale des Ingénieurs Issus de la Fusagx - Aigx) (2001), 4

Les flux de matières azotées mobilisés par les exploitations agricoles sont identifiés et quantifiés par divers modèles mathématiques. Ceux-ci sont conçus de manière à pouvoir être appliqués tant au ... [more ▼]

Les flux de matières azotées mobilisés par les exploitations agricoles sont identifiés et quantifiés par divers modèles mathématiques. Ceux-ci sont conçus de manière à pouvoir être appliqués tant au niveau d'une exploitation agricole qu'au niveau d'un territoire déterminé. Après avoir décrit succinctement ces modèles, leurs caractéristiques et leurs limites, le résultat de leur application aux agricultures flamande et wallonne est présenté. Il met en évidence une différence importante entre ces deux agricultures, notamment quant à leurs responsabilités environnementales. Les flux d'azote mobilisés par des exploitations agricoles existantes sont également estimés. Ils illustrent la grande diversité de comportement d'exploitations agricoles apparemment semblables. [less ▲]

Detailed reference viewed: 12 (2 ULg)
Full Text
Peer Reviewed
See detailLes contrats de rivière en Wallonie (Belgique) : retour d'expériences
Rosillon, Françis ULg; Vander Borght, Paul ULg

in Revue européenne de droit de l'environnement (2001), (4), 414-429

Detailed reference viewed: 28 (2 ULg)
Peer Reviewed
See detailPharma clinics le medicament du mois. Le nebivolol (Nobiten).
Scheen, André ULg

in Revue Médicale de Liège (2001), 56(11), 788-91

Nebivolol (Nobiten, Menarini) is a new beta-blocker recommended for the management of essential hypertension, at a dose of 5 mg once daily. It is administered as a racemic mixture of equal proportions of ... [more ▼]

Nebivolol (Nobiten, Menarini) is a new beta-blocker recommended for the management of essential hypertension, at a dose of 5 mg once daily. It is administered as a racemic mixture of equal proportions of d- and l-enantiomers. As a lipophilic agent, it is metabolised in the liver and transformed in several active metabolites, essentially via the CYP 2D6, an isoform of cytochrome P450 characterized by a genetic polymorphism. Nebivolol is highly specific for beta-1 adrenergic receptors; it is devoid of intrinsic sympathomimetic or membrane stabilising activity. Interestingly enough, it appears to have nitric oxide-mediated vasodilatory effects which might explain its favourable haemodynamic profile. Several comparative trials demonstrated an antihypertensive activity that was similar or slightly superior to that observed with various other reference antihypertensive agents. Nebivolol has an additive antihypertensive effect in combination with hydrochlorothiazide. All studies reported that the drug has a good clinical and biological tolerance profile. Therefore, nebivolol may be recommended as an alternative first-line treatment option for the management of patients with mild to moderate essential hypertension. [less ▲]

Detailed reference viewed: 357 (1 ULg)
Peer Reviewed
See detailRez. zu: Piirainen, Elisabeth: Phraseologie der westmünsterländischen Mundart
Möller, Robert ULg

in Zeitschrift für Dialektologie und Linguistik (2001), 69

Detailed reference viewed: 38 (1 ULg)
Full Text
Peer Reviewed
See detailInhibition of protein phosphatase PP1 in GH3B6, but not in GH3 cells, activates the MEK/ERK/c-fos pathway and the human prolactin promoter, involving the coactivator CPB/p300
Manfroid, Isabelle ULg; Martial, Joseph ULg; Muller, Marc ULg

in Molecular Endocrinology (Baltimore, Md.) (2001), 15(4), 625-37

The human (hPRL) PRL gene proximal promoter (-164/+15) is the target for numerous signal transduction pathways involving protein kinases. The inhibitor of Ser/Thr-protein phosphatases okadaic acid (OA ... [more ▼]

The human (hPRL) PRL gene proximal promoter (-164/+15) is the target for numerous signal transduction pathways involving protein kinases. The inhibitor of Ser/Thr-protein phosphatases okadaic acid (OA) was shown to induce this promoter in rat pituitary GH3B6 through a synergism between increased amounts of the ubiquitous factor AP-1 and the pituitary-specific factor Pit-1. Here we show that this activation results mainly from transcriptional stimulation of the c-fos promoter leading to increased AP-1 activity. We report the surprising absence of the hPRL and c-fos promoter stimulation by OA in GH3 cells, closely related to GH3B6 cells, and we use this discrepancy to dissect the precise mechanism of action. c-fos gene activation involves the mitogen-activated kinase (MAPK)-ternary complex factor (TCF) pathway and can be obtained by expressing active V12ras in both cell lines. We show that OA acts by inhibiting protein phosphatase PP1, thereby protecting MAPK kinase (MEK)1/2 and/or a MEK1/2-kinase from dephosphorylation. PP1 inhibition of MEK activation by V12ras does not occur in GH3 cells, indicating that a distinct, PP1-sensitive phosphorylation site is used in GH3B6 cells to activate the TCF pathway in GH3B6 cells. Finally, we show that the synergistic OA activation of the hPRL promoter by Pit-1 and AP-1 is independent of the Pit-1 transactivation domain and is mediated by the general coactivator (CRE-binding protein)-binding protein (CBP)/p300. [less ▲]

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailLa photographie aérienne en période de sècheresse comme source de renseignements géologiques en Wallonie
Quoilin, H.; Ozer, André ULg; Cornet, Yves ULg et al

in Bulletin de la Société Géographique de Liège (2001), 40(2001-1), 33-40

Detailed reference viewed: 65 (11 ULg)
Full Text
See detailConsidérations sur le taux du ressort lorsque les bases de détermination de la valeur du litige font défaut
Boularbah, Hakim ULg

in Revue de Droit Judiciaire et de la Preuve = Tijdschrift voor Procesrecht en Bewijsrecht (2001)

Detailed reference viewed: 51 (0 ULg)
Peer Reviewed
See detailComment j'explore ... les differentes formes de diabete sucre: diagnostic differentiel clinique et biologique.
Scheen, André ULg; Philips, Jean-Christophe ULg; Luyckx, Françoise ULg et al

in Revue Médicale de Liège (2001), 56(9), 650-5

Owing to the increasing prevalence of diabetes mellitus and the various aspects of this disease, we present a practical approach which allows the clinician to more easily differentiate type 1 diabetes ... [more ▼]

Owing to the increasing prevalence of diabetes mellitus and the various aspects of this disease, we present a practical approach which allows the clinician to more easily differentiate type 1 diabetes, type 2 diabetes and secondary diabetes of pancreatic origin, i.e. the most common forms of diabetes mellitus. Such an approach uses simple diagnostic criteria, based upon both clinical characteristics (family history, personal history, clinical presentation) and biological markers (C-peptide, autoantibodies,...). A right diagnosis should allow to optimize the management of the diabetic patient. [less ▲]

Detailed reference viewed: 60 (5 ULg)
Full Text
Peer Reviewed
See detailEssais d’induction artificielle de la lactation chez des génisses âgées de 6 a 7 mois
Nchare, A.; Salaheddine, M.; Desbuleux, H. et al

in Annales de Médecine Vétérinaire (2001), 145(6, Suppl. S), 365-371

The rates of successful gene's manipulations are very low in domestic mammals. In addition the period between generations in cows is long. Artificial induction of lactation in young animals could improve ... [more ▼]

The rates of successful gene's manipulations are very low in domestic mammals. In addition the period between generations in cows is long. Artificial induction of lactation in young animals could improve manipulation yield for genes what are expressed in the udder, by anticipating the control of transgen expression in milk, a long time before the beginning of the milk production in normal condition. Using this method, the early selection of real transgenic animals would be possible. Between November 1999 and April 2000, lactation was induced in non-transgenic heifers aged from 6 to 7 months, in 2 trials based on short time hormonal treatment, with the goal of verifying the efficiency of the technique on immature heifers, and setting up a simple and reliable treatment scheme applicable on young animals. Interesting lactations (35 to 974 ml/day) were obtained, but the milk yield was low compared to adult performances. Results of the 2 trials were different, in relation with the galenical form of progesterone used and the frequency of drugs administration. So, these trials provide an efficient treatment scheme for induction of lactation in young heifers. [less ▲]

Detailed reference viewed: 92 (5 ULg)
Full Text
Peer Reviewed
See detailIntensive and Prolonged Health Promotion Strategy May Increase Awareness of Osteoporosis among Postmenopausal Women
Tellier, V.; De Maeseneer, J.; De Prins, L. et al

in Osteoporosis International (2001), 12(2), 131-5

The aim of the study was to measure the results of a 15-year health promotion strategy towards osteoporosis, in an urban community of subjects over 45 years old, in terms of osteoporosis awareness and ... [more ▼]

The aim of the study was to measure the results of a 15-year health promotion strategy towards osteoporosis, in an urban community of subjects over 45 years old, in terms of osteoporosis awareness and handling. To this end an ancillary study to a large survey of the Belgian population's self-perceived health status was carried out. A rectangular sample of 4800 individuals over 45 years old was randomly selected in two Belgian cities, among the affiliates of the two main health insurance providers. One of the cities (Liege) had been, since the early 1980s, the target of a constant health promotion strategy, directed to both the medical community and the general population, aimed at increasing osteoporosis awareness in women after the menopause. During the same period, no particular steps were taken in the other city (Aalst) to increase osteoporosis awareness in the community. In our study, the participants were asked to spontaneously report any chronic, serious and/or severe disorders that they had been suffering from, for at least 6 months, during the previous 12 months. They also provided a list of drugs they were taking at the time of the survey. Osteoporosis was reported to be a disease affecting 1.5% of men in Aalst and 1.3% of men in Liege (p = 0.61). For women, osteoporosis was reported to be present in 4.8% in Aalst and 10.8% in Liege (p<0.001). Self-reporting of osteoporosis prevalence in Liege was statistically significantly higher in women aged 45-64 years, 65-74 years or over 75 years (p<0.001). Obesity, alcohol consumption or physical activity were equally distributed between women from Liege and Aalst. Prescription drugs used for osteoporosis had been delivered to a similar proportion of men in Aalst and Liege. In women, a statistically significant difference in these prescription drugs was observed between Liege and Aalst, both for the overall population (p<0.001) and in each of the age classes (p<0.001 for 45-64 years and 65-74 years; p<0.009 for over 75 years). A continuous long-term health promotion strategy, directed toward both physicians and the general population, thus appears to increase awareness about osteoporosis in women over 45 years and/or in the medical community. This is reflected by an increase in self-reported prevalence of osteoporosis and in the prescription of drugs aimed at prevention and treatment of this disorder. Whether these observations reflect an appropriate diagnosis and a proper handling of the disease remains to be evaluated by objective diagnostic tools such as bone densitometry and by an evaluation of the effectiveness of prescription practices in postmenopausal women. [less ▲]

Detailed reference viewed: 55 (1 ULg)
Full Text
Peer Reviewed
See detailFrontières d’efficacité et processus d’appariement sur le marché du travail au Maroc
Ibourk, Aomar; Perelman, Sergio ULg

in Economie et Prévision (2001), (150-151), 33-45

La capacité d’un marché du travail à générer de nouveaux emplois à partir d’un stock donné de postes vacants et de chômeurs est interprétée comme une forme d’efficacité transactionnelle. Elle peut être ... [more ▼]

La capacité d’un marché du travail à générer de nouveaux emplois à partir d’un stock donné de postes vacants et de chômeurs est interprétée comme une forme d’efficacité transactionnelle. Elle peut être mesurée à partir de l’estimation d’une fonction d’appariement qui décrit la situation d’échange entre la demande, exprimée par les firmes, et l’offre, représentée par les travailleurs à la recherche d’un emploi. Dans cet article, nous proposons l’utilisation des techniques des frontières d’efficacité pour ces estimations. Deux méthodes alternatives, paramétrique et non paramétrique, sont appliquées au cas des marchés du travail régionaux au Maroc. Les résultats obtenus permettent une évaluation de l’efficacité des appariements sur chacun des marchés ainsi qu’une évaluation de l’activité des centres d’information et d’orientation pour l’emploi (CIOPE) qui ont été créés au début des années quatre-vingt-dix aux fins de faciliter l’appariement de l’offre et de la demande des diplômés. [less ▲]

Detailed reference viewed: 73 (3 ULg)
Full Text
Peer Reviewed
See detailDéveloppement agricole et protection du milieu
Debouche, Charles ULg

in Les nouvelles de l'Automne (2001), (4e trimestre), 14-16

La Filière porcine wallonne sous-tend ses activités de fédération et de promotion par une analyse du contexte règlementaire. L'expansion qu'elle encourage du secteur porcin doit trouver place dans celui ... [more ▼]

La Filière porcine wallonne sous-tend ses activités de fédération et de promotion par une analyse du contexte règlementaire. L'expansion qu'elle encourage du secteur porcin doit trouver place dans celui-ci. Si la situation est aujourd'hui délicate, une embellie est en vue. Les aides 2000 à l'investissement des agriculteurs favorisent la production porcine. Le permis d'environnement ira dans ce même sens. [less ▲]

Detailed reference viewed: 13 (1 ULg)
Full Text
Peer Reviewed
See detailColomb interactions and the 17 August 1999 Izmit, Turkey earthquake
King, G. C. P.; Hubert, Aurelia ULg; Nalbant, S. S. et al

in Comptes Rendu de l’Académie des Sciences de Paris - Série 2. Sciences de la terre et des planètes (2001), 333(rie 2. Sciences de la terre et des planètes), 557-569

At 00:02 GMT (03:02 local time) on 17 August, 1999 a magnitude 7.4 (Ms) earthquake occurred 100 km east of Istanbul causing extensive destruction. The event was expected and several scientists have ... [more ▼]

At 00:02 GMT (03:02 local time) on 17 August, 1999 a magnitude 7.4 (Ms) earthquake occurred 100 km east of Istanbul causing extensive destruction. The event was expected and several scientists have published and attempted to publicize the danger. A paper on stress interactions for NW Turkey (J. Geophys. Res. 103 (1998) 24466–24469) concluded that “by combining the stress change map with the map of active faulting, likely locations for the occurrence of future earthquakes can be refined; faults in the Izmit Bay area, the western part of Biga Peninsula, the Saroz Gulf and a part of western Sea of Marmara must be regarded as posing a specific hazard”. An extension of that study is described here. It is shown that the Izmit (1999) earthquake loaded faults both to the east and west of the Izmit rupture. About three months after the Izmit event an M 7.2 earthquake occurred with an epicenter at Duzce extending the Izmit rupture to the east. In the Marmara Sea, west of Izmit, faults have been loaded by between 1 and 5 bar; 5 to 30 % of typical earthquake stress drops in the region suggesting the likelihood of a future event. The risk of a major event on a fault depends not just on stress increases associated with an individual earthquake, but also on the longer-term earthquake history and on tectonic loading. The roles of both are examined over two time periods from 1900 to 1999 and 1700 to 1999. Whatever interpretation we place on the data we conclude that one or two events as great or greater than the recent one is likely to occur within the next few decades near to the northern coast of the Marmara Sea [less ▲]

Detailed reference viewed: 26 (0 ULg)
Full Text
See detailLes mélèzes
Rondeux, Jacques ULg; Pauwels, D.

in Fiche technique (2001)

Detailed reference viewed: 15 (5 ULg)
Full Text
See detailPlante-t-on l'épicéa n'importe où ? L'apport d'une analyse objective de la pessière wallonne.
Claessens, Hugues ULg; Lecomte, Hugues; Lejeune, Philippe ULg et al

in Forêt Wallonne (2001), (49-50), 45-51

Depuis son introduction dans la sylviculture belge au milieu du XIXe siècle, l'épicéa s'est progressivement imposé principalement grâce à sa bonne adaptation aux difficiles conditions écologiques de l ... [more ▼]

Depuis son introduction dans la sylviculture belge au milieu du XIXe siècle, l'épicéa s'est progressivement imposé principalement grâce à sa bonne adaptation aux difficiles conditions écologiques de l'Ardenne, la facilité de sa culture et sa haute productivité en sols pauvres. Il est devenu la première essence de la forêt wallonne où il représente près de la moitié du volume de bois sur pied. Mais petit à petit, l'impact négatif de sa culture à grande échelle sur l'environnement s'est aussi révélé, notamment lors de son introduction dans des milieux fragiles qu'il a altérés, voire détruits. Ces erreurs ont progressivement amené de plus en plus d'observateurs de notre patrimoine naturel à rejeter globalement l'épicéa et sa culture en Belgique. Ces cas malheureux sur lesquels se sont focalisées l'opinion publique et scientifique sont-ils l'exeption ? Dans quelle mesure l'épicéa a-t-il colonisé à tort certains milieux ? Dans quelles conditions sa culture est-elle acceptable, tolérée ou à exclure ? C'est à ce type de question que la présente étude tente de répondre. [less ▲]

Detailed reference viewed: 210 (27 ULg)
Full Text
Peer Reviewed
See detailFetal renal hyperechogenicity in intrauterine growth retardation : importance and outcome.
Suranyi, A.; Retz, C.; Foidart, Jean-Michel ULg et al

in Pediatric Nephrology : Journal of the International Pediatric Nephrology Association (2001), 16(7), 575-580

The object of the study was to investigate the outcome in growth-retarded newborns who were diagnosed with fetal renal hyperechogenicity without anatomical abnormality during any stage of pregnancy ... [more ▼]

The object of the study was to investigate the outcome in growth-retarded newborns who were diagnosed with fetal renal hyperechogenicity without anatomical abnormality during any stage of pregnancy. Depending on the fetal renal ultrasonography result, the cases were divided into two study groups. There was an intrauterine growth-retarded group with fetal renal medullary hyperechogenicity and another group without fetal renal medullary hyperechogenicity. The renal parenchyma was observed after birth, within the first 5 days of life, and several times until the 14th postpartum day in positive cases. Hyperechogenic renal medullae were detected in 25 of 90 cases with intrauterine growth retardation during the 8-month study period. This may be an in utero cause of subsequent intrauterine and neonatal complications, such as cesarean section because of fetal distress (36%), perinatal infection (24%), treatment in a neonatal intensive care unit (52%), or increased perinatal mortality (8%). The results demonstrate that fetuses with hyperechoic medullae had 1.5 times the risk of an abnormal outcome compared with fetuses with normal echoic kidneys and intrauterine growth retardation. Detailed ultrasound examinations of renal parenchyma appear to be useful for the prenatal diagnosis of intrauterine hypoxia, allowing the detection of possible pathological fetal conditions in utero. [less ▲]

Detailed reference viewed: 45 (0 ULg)
Full Text
See detailUn exemple de gestion originale de la nature : la restauration de forêts alluviales de l’Elbe
Claessens, Hugues ULg

in Parcs & Réserves (2001), 56(1), 23-25

Detailed reference viewed: 26 (4 ULg)
Full Text
Peer Reviewed
See detailHelioseismic Tests of the New Los Alamos LEDCOP Opacities
Neuforge-Verheecke, C.; Guzik, J. A.; Keady, J. J. et al

in Astrophysical Journal (2001), 561(1), 450-454

We compare the helioseismic properties of two solar models, one calibrated with the OPAL opacities and the other with the recent Los Alamos LEDCOP (Light Element Detailed Configuration Opacity) opacities ... [more ▼]

We compare the helioseismic properties of two solar models, one calibrated with the OPAL opacities and the other with the recent Los Alamos LEDCOP (Light Element Detailed Configuration Opacity) opacities. We show that, in the radiative interior of the Sun, the small differences between the two sets of opacities (up to 6% near the base of the convection zone) lead to noticeable differences in the solar structure (up to 0.3% in sound speed), with the OPAL model being the closest to the helioseismic data. More than half of the difference between the two opacity sets results from the interpolation scheme and from the relatively widely spaced temperature grids used in the tables. The remaining 3% intrinsic difference between the OPAL and the LEDCOP opacities in the radiative interior of the Sun is well within the error bars on the opacity calculations resulting from the uncertainties on the physics. We conclude that both the OPAL and LEDCOP opacities produce solar models in close agreement with helioseismic inferences, but discrepancies still persist at the level of 0.6% between the calculated and inferred sound speed in the radiative interior of the Sun. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailLe sort des obligations du bailleur en cas de contre-préavis du locataire. Note sous Cass., 22 juin 1998
Kohl, Benoît ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2001)

Detailed reference viewed: 15 (1 ULg)
Peer Reviewed
See detailImmunisation against East Coast fever by the infection and treatment method: evaluation of the use of ice baths for field delivery and appraisal of an acid formulation of long-acting tetracycline.
Marcotty, T.; Billiouw, M.; Chaka, G. et al

in Veterinary Parasitology (2001), 99(3), 175-87

Immunisation by the infection and treatment method using the Katete strain is currently the most efficient prophylactic technique to control East Coast fever (ECF) in the endemic areas of the Eastern ... [more ▼]

Immunisation by the infection and treatment method using the Katete strain is currently the most efficient prophylactic technique to control East Coast fever (ECF) in the endemic areas of the Eastern Province of Zambia. The maintenance of the cold chain in liquid nitrogen up to the time of inoculation and the cost of the reference long-acting oxytetracycline (Terramycin LA, Pfizer) are the main drawbacks of the method. The work presented in this paper aims at reducing the cost of immunisation against ECF by using an ice bath for the field delivery and a cheaper long-acting oxytetracycline formulation as chemotherapeutic agent. In experimental conditions, the results from 40 calves immunised after various periods of storage on ice ranging from 4 to 32 h indicate that deferred immunisation performed with a stabilate kept on ice for up to 6h after thawing has an efficiency of 90%. Moreover, sporozoites kept on ice were still surviving 32 h after thawing. In a field trial, 91 calves were inoculated with a stabilate kept for 3.5-5.5 h after thawing and dilution whereas 86 calves were immunised using the standard method. Clinical and parasitological reactions to immunisation were monitored as well as the seroconversion. In the field trial, the deferred immunisation was more efficient than the standard method. The acid formulation of oxytetracycline that was tested was found as suitable as the reference alkaline formulation for the chemotherapeutic control of the Katete strain in ECF immunisation. One indoor trial was carried out on 10 animals and a field trial involved 93 calves. [less ▲]

Detailed reference viewed: 21 (2 ULg)
Peer Reviewed
See detailPratique de l'exercice musculaire chez le patient diabetique.
Jandrain, Bernard ULg; Scheen, André ULg

in Revue Médicale de Liège (2001), 56(5), 300-5

Muscular exercise is recommended in patients with type 1 or type 2 diabetes mellitus and is part of the overall management, in combination with diet, oral antidiabetic agents and/or insulin. From a ... [more ▼]

Muscular exercise is recommended in patients with type 1 or type 2 diabetes mellitus and is part of the overall management, in combination with diet, oral antidiabetic agents and/or insulin. From a pathophysiological point of view, regular physical activity enhances insulin sensitivity, thus contributing to improve blood glucose control and to reduce cardiovascular risk factors associated to diabetes mellitus. From a practical point of view, however, muscular exercise in a diabetic patient requires special caution, in particular careful selection of the type of exercise, respect of metabolic and/or cardiovascular contraindications, and appropriate adjustment of current pharmacological/dietary treatment. [less ▲]

Detailed reference viewed: 72 (1 ULg)
Full Text
Peer Reviewed
See detailLocalized iterative generalized multipole technique for large two-dimensional scattering problems
Obelleiro, Fernando; Landesa, Luis; Rodriguez, Jose Luis et al

in Ieee Transactions On Antennas And Propagation (2001), 49(6), 961-970

In this work, we propose a novel and efficient solution for the generalized multipole technique (GMT): the localized iterative generalized multipole technique (LIGMT). In LIGMT, an analytic constraint is ... [more ▼]

In this work, we propose a novel and efficient solution for the generalized multipole technique (GMT): the localized iterative generalized multipole technique (LIGMT). In LIGMT, an analytic constraint is imposed on the power radiated by the set of multipole sources sharing the same origin, rendering it minimum over a given angular sector. In this way, the power radiated by each set of multipoles is confined to a different section of the scatterer surface. It follows that each set of multipole coefficients can be solved step by step via an iterative process, which circumvents the need to solve the large and full matrix equation. This implies a significant reduction of the computational and storage cost, enhancing the scope of application of the GMT method to larger problems. [less ▲]

Detailed reference viewed: 18 (0 ULg)
Full Text
Peer Reviewed
See detailTriassic and Jurassic lithostratigraphic units (Belgian Lorraine)
Boulvain, Frédéric ULg; Belanger, I.; Delsate, D. et al

in Geologica Belgica (2001), 4(1-2), 113-119

A multidisciplinary study of some extensively cored boreholes together with the new 1/25,000 geological mapping of Wallonia led us to propose a new lithostratigraphic canvas for Belgian Lorraine. This ... [more ▼]

A multidisciplinary study of some extensively cored boreholes together with the new 1/25,000 geological mapping of Wallonia led us to propose a new lithostratigraphic canvas for Belgian Lorraine. This area is located on the NE border of the Paris Basin, south of the Ardennes; the studied stratigraphic interval covers the Keuper to the Bajocian. [less ▲]

Detailed reference viewed: 48 (2 ULg)
Full Text
See detailProperties of ordinary and exotic hadrons
Stancu, Floarea ULg

in Few-Body Systems Supplementum (2001), 13

I discuss properties of ordinary and exotic hadrons as described by two distinct constituent quark models. These are the one gluon exchange (OGE) and the Goldstone boson exchange (GBE) models. I also ... [more ▼]

I discuss properties of ordinary and exotic hadrons as described by two distinct constituent quark models. These are the one gluon exchange (OGE) and the Goldstone boson exchange (GBE) models. I also discuss the interaction between hadrons starting from their quark structure. The case of the $NN$ is presented in some details. [less ▲]

Detailed reference viewed: 14 (6 ULg)
Full Text
Peer Reviewed
See detailLe contrôle de la constitutionnalité des lois aux Pays-Bas
Kohl, Benoît ULg

in Chroniques de Droit Public = Publiekrechtelijke Kronieken (2001)

Detailed reference viewed: 45 (2 ULg)
Full Text
Peer Reviewed
See detailStrontium ranelate increases cartilage matrix formation.
Henrotin, Yves ULg; Labasse, Alain; Zheng, S. X. et al

in Journal of Bone and Mineral Research (2001), 16(2), 299-308

Based on previous studies showing that strontium ranelate (S12911) modulates bone loss in osteoporosis, it could be hypothesized that this drug also is effective on cartilage degradation in osteoarthritis ... [more ▼]

Based on previous studies showing that strontium ranelate (S12911) modulates bone loss in osteoporosis, it could be hypothesized that this drug also is effective on cartilage degradation in osteoarthritis (OA). This was investigated in vitro on normal and OA human chondrocytes treated or not treated with interleukin-1beta (IL-1beta). This model mimics, in vitro, the imbalance between chondroformation and chondroresorption processes observed in vivo in OA cartilage. Chondrocytes were isolated from cartilage by enzymatic digestion and cultured for 24-72 h with 10(-4)-10(-3) M strontium ranelate, 10(-3) M calcium ranelate, or 2 x 10(-3) M SrCl2 with or without IL-1beta or insulin-like growth factor I (IGF-I). Stromelysin activity and stromelysin quantitation were assayed by spectrofluorometry and enzyme amplified sensitivity immunoassay (EASIA), respectively. Proteoglycans (PG) were quantified using a radioimmunoassay. Newly synthesized glycosaminoglycans (GAGs) were quantified by labeled sulfate (Na2(35)SO4) incorporation. This method allowed the PG size after exclusion chromatography to be determined. Strontium ranelate, calcium ranelate, and SrCl2 did not modify stromelysin synthesis even in the presence of IL-1beta. Calcium ranelate induced stromelysin activation whereas strontium compounds were ineffective. Strontium ranelate and SrCl2 both strongly stimulated PG production suggesting an ionic effect of strontium independent of the organic moiety. Moreover, 10(-3) M strontium ranelate increased the stimulatory effect of IGF-I (10(-9) M) on PG synthesis but did not reverse the inhibitory effect of IL-1beta. Strontium ranelate strongly stimulates human cartilage matrix formation in vitro by a direct ionic effect without stimulating the chondroresorption processes. This finding provides a preclinical basis for in vivo testing of strontium ranelate in OA. [less ▲]

Detailed reference viewed: 17 (6 ULg)
Peer Reviewed
See detailLa représentation des travailleurs à l’heure de la flexibilité : conséquences, enjeux et perspectives
Agro, Linda ULg; Dieu, Anne-Marie; Schoenaers, Frédéric ULg

in Revue de Gestion des Ressources Humaines (2001), 39

Detailed reference viewed: 62 (22 ULg)
Full Text
Peer Reviewed
See detailDown-Regulation of MT1-MMP expression by the alpha3 chain of type IV collagen inhibits bronchial tumor cell line invasion
Martinella-Catusse, C.; Polette, M.; Noël, Agnès ULg et al

in Laboratory Investigation : Journal of Technical Methods & Pathology (2001), 81

The basement membrane (BM) is the first barrier encountered by tumor cells when they become invasive. Moreover, some invasive tumor clusters are surrounded by a remnant or neosynthetized BM material. We ... [more ▼]

The basement membrane (BM) is the first barrier encountered by tumor cells when they become invasive. Moreover, some invasive tumor clusters are surrounded by a remnant or neosynthetized BM material. We have previously reported the presence of a particular alpha chain of type IV collagen, the alpha3(IV) chain, in bronchopulmonary carcinomas. This chain was not detected in the normal bronchial epithelium, but was found around some invasive tumor cluster BM. In the present study, we examined the effects of the alpha3(IV) chain on the invasive properties of bronchial tumor cell lines, with special emphasis on their expression of matrix metalloproteinase-2 (MMP-2) and its activator, membrane type 1-matrix metalloproteinase (MT1-MMP), which is largely involved in tumor progression. Two epithelial bronchial cell lines (16HBE14o- and BZR), showing different invasive abilities, were evaluated. Using the Boyden chamber invasion assay, we demonstrated that the alpha3(IV) chain inhibits the invasive properties of BZR cells and modifies their morphology by inducing an epithelial cell shape. In the presence of the recombinant NC1 domain of the alpha3(IV) chain, the expression of MMP-2 and tissue inhibitor of metalloproteinase-2 (TIMP-2) was not modified in either cell line. The NC1 alpha3(IV) domain did not modulate the MT1-MMP expression of noninvasive 16HBE14o- cells, whereas a 50% decrease of MT1-MMP mRNA was observed in invasive BZR cells. Accordingly, Western blot analyses showed a disappearance of the 45-kd MT1-MMP form when BZR cells were treated with the recombinant NC1 alpha3(IV) domain. These findings suggest that the alpha3 chain of type IV collagen may play a role in tumor invasion, at least by decreasing the expression and synthesis of MT1-MMP. [less ▲]

Detailed reference viewed: 45 (7 ULg)
See detailEvaluer une réforme pédagogique : La généralisation de l'apprentissage d'une langue seconde à l'école primaire
Blondin, Christiane ULg; Straeten, Marie-Hélène

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 163-173

La recherche Généralisation de l'apprentissage d'une langue moderne à l'école primaire, réalisée avec le soutien du Ministère de la Communauté française vise à évaluer la mise en place de l'innovation que ... [more ▼]

La recherche Généralisation de l'apprentissage d'une langue moderne à l'école primaire, réalisée avec le soutien du Ministère de la Communauté française vise à évaluer la mise en place de l'innovation que constitue l'enseignement obligatoire des langues en cinquième et sixième années primaires, dans les écoles fondamentales organisées ou subventionnées par la Communauté française.Il est donc nécessaire de récolter un maximum d'informations quant aux ressources des équipes éducatives et plus particulièrement des maîtres de langue face à cette réforme, quant aux difficultés rencontrées, aux aides et aux soutiens possibles, tant d'un point de vue méthodologique qu'institutionnel ou administratif. A terme, cette recherche veut proposer des pistes pour assurer la réussite de l'innovation. Le présent article situe cette recherche dans une perspective de pilotage d'innovation. [less ▲]

Detailed reference viewed: 33 (3 ULg)
Full Text
Peer Reviewed
See detailRole Of The Proline-Rich Motif Of Bovine Leukemia Virus Transmembrane Protein Gp30 In Viral Load And Pathogenicity In Sheep
Reichert, M.; Winnicka, A.; Willems, Luc ULg et al

in Journal of Virology (2001), 75(17),

Detailed reference viewed: 12 (1 ULg)
Full Text
Peer Reviewed
See detailAuto-observation des modalites d'apprentissage en situation de projet. Metacognition mathetique au cours de PARMs; L'universite, un espace d'innovation pedagogique ?
Leclercq, Dieudonné ULg; Denis, Brigitte ULg

in Revue des Sciences de l'Education (2001), 27(2), 421-440

This article presents the training objectives (motivational, metacognitive, instrumental, and disciplinary) of a pedagogical method known as PARMs (multimedia reciprocal animation project) and procedures ... [more ▼]

This article presents the training objectives (motivational, metacognitive, instrumental, and disciplinary) of a pedagogical method known as PARMs (multimedia reciprocal animation project) and procedures for self-observation of learning as experienced by university students. The authors describe a series of didactic-mathetic activities related to training objectives, as well as those learning strategies promoted in the PARMs course. Two instruments to measure metacognitive thinking are presented: « Questionnaire on progress » and « Questionnaire on mathetical self-description ». The results of these questionnaires is then discussed. [less ▲]

Detailed reference viewed: 179 (11 ULg)
Peer Reviewed
See detailInulin: its physicochemical properties and technological functionality.
Blecker, Christophe ULg; Chevalier, J. P.; Herck, J C van et al

in Recent Research Developments in Agricultural & Food Chemistry (2001), 5

This review examines the present state of knowledge on the physicochemical properties and technological functionality of inulin. First, structure and conformation are described. Secondly, solubility and ... [more ▼]

This review examines the present state of knowledge on the physicochemical properties and technological functionality of inulin. First, structure and conformation are described. Secondly, solubility and gelation are precisely detailed. Finally, the numerous advantages offered by this functional food are described. [less ▲]

Detailed reference viewed: 371 (16 ULg)
Full Text
Peer Reviewed
See detailStudies in Bacidia sensu lato (lichenized Ascomycetes: Lecanorales). II. Six new combinations in Fellhanera Vezda
Lücking, Robert; Cáceres, M.E.S.; Kalb, Klaus et al

in Lichenologist (2001), 33

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailMonitoring of erythropoiesis by the serum transferrin receptor and erythropoietin.
Fillet, Georges ULg; Beguin, Yves ULg

in Acta Clinica Belgica (2001), 56(3), 146-54

Virtually all cells have transferrin receptors (a transmembrane glycoprotein) on their surface but in a normal adult, 80% of them are in the erythroid marrow. Some of them are lost into the circulation ... [more ▼]

Virtually all cells have transferrin receptors (a transmembrane glycoprotein) on their surface but in a normal adult, 80% of them are in the erythroid marrow. Some of them are lost into the circulation where they can be measured by immuno-assays. A direct and highly significant correlation exists between serum transferrin receptor level and erythron transferrin uptake in humans. The measurement of serum transferrin receptor has wide clinical applications for the quantitation of erythropoiesis. It can be used to study erythropoiesis in situations in which ferrokinetics is not acceptable such as pregnancy. It is particularly useful for serial studies, e.i., for monitoring the recovery of erythropoiesis after stem cell transplantation or after treatment with erythropoietin. Combined with the determination of serum erythropoietin, both evaluated in relation to the degree of anemia, they provide a physiological approach to the diagnosis of anemia. Thus, the simultaneous determination of hematocrit, reticulocytes, serum transferrin receptor and serum erythropoietin has high discriminatory value in distinguishing between a defect in erythroid proliferation, maturation or red cell survival. It is also particularly useful for detecting the presence of multiple mechanisms of anemia in the same patient. [less ▲]

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailDoes ovarian surgery for endometriomas impair the ovarian response to gonadotropin?
Donnez, Jacques; Wyns, Christine; NISOLLE, Michelle ULg

in Fertility and Sterility (2001), 76(4), 662-5

Objective: To evaluate the ovarian response to stimulation conducted for IVF treatment in women who have undergone conservative surgery for endometriomas. Design: Retrospective study with prospective ... [more ▼]

Objective: To evaluate the ovarian response to stimulation conducted for IVF treatment in women who have undergone conservative surgery for endometriomas. Design: Retrospective study with prospective selection of participants and controls. Setting: University infertility clinic. Patient(s): A series of 374 women who underwent in vitro fertilization (IVF). The study group consisted of 85 patients with ovarian endometriomas who had undergone laparoscopic surgery in an attempt to become pregnant, but had failed within a year of surgery. The control group consisted of 289 patients with tubal factor infertility. Intervention(s): IVF-embryo transfer procedures. Main Outcome Measure(s): Stimulation parameters, fertilization, implantation, and pregnancy rates were analyzed in both groups. Result(s): There was no significant difference between the two groups in stimulation parameters or IVF outcome. Conclusion(s): A total of 820 cycles were analyzed. A similar IVF-ET outcome was observed in patients with endometriosis after ablation of endometriomas compared to women with tubal factors. In conclusion, endometrioma surgery by internal wall vaporization does not impair IVF outcome. The clinical pregnancy rate was respectively 37.4% and 34.6% in the endometriosis group and the control group. [less ▲]

Detailed reference viewed: 18 (3 ULg)
Full Text
Peer Reviewed
See detailCentral self-tolerance by thymic presentation of self-antigens and autoimmunity
Geenen, Vincent ULg; Martens, Henri ULg; Hansenne, Isabelle et al

in Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents (2001), 1

Before reacting against non-self infectious agents, the immune system is educated to tolerate the host molecular structure (self). The induction of self-tolerance is a multistep process that begins in the ... [more ▼]

Before reacting against non-self infectious agents, the immune system is educated to tolerate the host molecular structure (self). The induction of self-tolerance is a multistep process that begins in the thymus during fetal ontogeny (central tolerance) and also involves inactivating mechanisms outside the thymus (peripheral tolerance). The thymus is the primary lymphoid organ implicated in the development of competent and self-tolerant T cells. During ontogeny, T cell progenitors originating from hemopoietic tissues (yolk sac, fetal liver, and then bone marrow) enter the thymus and undergo a program of proliferation, T cell receptor (TCR) gene rearrangement, maturation and selection. Close interactions between thymocytes (pre-T cells) and the thymic cellular environment are crucial both for T cell development and induction of central self-tolerance. Thymic epithelial and stromal cells synthesize polypeptides belonging to various neuroendocrine families. The thymic repertoire of neuroendocrine-related precursors transposes at the molecular level the dual role of the thymus in T cell negative and positive selection. Thymic precursors not only constitute a source of growth peptides for cryptocrine signaling between thymic stromal cells and pre-T cells, but are also processed in a way that leads to the presentation of self-antigens by thymic major histocompatibility complex (MHC) proteins. Thymic neuroendocrine self-antigens often correspond to peptide sequences highly conserved during the evolution of their corresponding family. The thymic presentation of some neuroendocrine self-antigens is not restricted by MHC alleles. Following the presentation of neuroendocrine self-antigens by thymic MHC proteins, the T cell system might be educated to tolerate main hormone families. Recent experiments argue that a defect in the thymic essential tolerogenic function is implicated as an important factor in the pathophysiology of many autoimmune diseases. [less ▲]

Detailed reference viewed: 32 (3 ULg)
Full Text
Peer Reviewed
See detailOral vitamin C attenuates acute ischaemia-reperfusion injury in skeletal muscle.
Kearns, S. R.; Moneley, D.; Murray, P. et al

in Journal of Bone & Joint Surgery, British Volume (2001), 83(8), 1202-6

Ischaemia-reperfusion injury (IRI) is caused by endothelial and subendothelial damage by neutrophil-derived oxidants. Vitamin C is an antioxidant which attenuates endothelial injury after IRI. Our aim was ... [more ▼]

Ischaemia-reperfusion injury (IRI) is caused by endothelial and subendothelial damage by neutrophil-derived oxidants. Vitamin C is an antioxidant which attenuates endothelial injury after IRI. Our aim was to evaluate the effect of oral vitamin C in the prevention of IRI in skeletal muscle. We used a model of cross-clamping (3 hours) and reperfusion (1 hour) of the cremaster muscle in rats. Muscle function was assessed electrophysiologically by electrical field stimulation. Infiltration by neutrophils was determined by the activity of tissue myeloperoxidase (MPO) and tissue oedema by the wet-to-dry ratio. Neutrophil respiratory burst activity was measured in control animals and groups pretreated with vitamin C. IRI significantly decreased muscle function and increased muscle neutrophil MPO activity and muscle oedema. Pretreatment with vitamin C preserved muscle function and reduced tissue oedema and neutrophil infiltration. Neutrophil respiratory burst activity was reduced in the group treated with vitamin C compared with the control group. We conclude that pretreatment with oral vitamin C protects against acute muscle IRI, possibly by attenuating neutrophil respiratory burst activity. [less ▲]

Detailed reference viewed: 40 (2 ULg)
Peer Reviewed
See detailCharge critique et longueur de flambement des éléments à inertie variable et aux conditions d'extrémité élastiques
Latteur, Pierre ULg

in revue scientifique des Instituts supérieurs industriels francophones de Belgique (2001), 15

Detailed reference viewed: 150 (2 ULg)
Full Text
Peer Reviewed
See detailImmediate and long-term clinical and angiographic results from Wiktor stent treatment for true bifurcation narrowings.
Anzuini, A.; Briguori, C.; Rosanio, S. et al

in American Journal of Cardiology (2001), 88(11), 1246-50

From January 1996 to December 1998, 90 consecutive patients with true bifurcation lesions underwent percutaneous coronary angioplasty with Wiktor stent implantation in our centers. In 1 group (group I, n ... [more ▼]

From January 1996 to December 1998, 90 consecutive patients with true bifurcation lesions underwent percutaneous coronary angioplasty with Wiktor stent implantation in our centers. In 1 group (group I, n = 45), a simple approach (main vessel stenting and balloon angioplasty of the side branch) was pursued. In the other group (group II, n = 45), both the main vessel and the side branch were stented ("T" technique). There was no significant difference in clinical and angiographic characteristics between the 2 groups. Angiographic and procedural successes were 100% and 95.6%, respectively, in both groups. Angiographic results for the side branch were better in group II than in group I. In-hospital and long-term (12 month) major cardiac events were similar in the 2 groups. Target lesion revascularization was 15.5% in group I and 35.5% in group II (p = 0.12). In the main vessel, restenosis rate was 12.5% in group I and 25% in group II (p = 0.15). In the side branch, restenosis rate was 37.5% in group II and 12.5% in group I (p = <0.05; odds ratio 2.42; 95% confidence interval 1.05 to 6.26). Event-free probability at 12 months was 61% in group II and 80% in group I (p = 0.10). When dealing with true bifurcation lesions, a simple strategy is associated with a lower risk of restenosis in the side branch. In contrast, a complex approach does not appear to give any benefit in terms of early or long-term outcome or restenosis rate. [less ▲]

Detailed reference viewed: 23 (1 ULg)
Full Text
Peer Reviewed
See detailLa distribution des industries dans une région : des images multiples
Merenne-Schoumaker, Bernadette ULg; Devillet, Guénaël ULg

in Bulletin de la Société Géographique de Liège (2001), 40

How to apprehend the industrial distribution in a region ? How to analyse their pattern ? Such are the two main questions discussed in this paper which tries to give an answer by a progress in five steps ... [more ▼]

How to apprehend the industrial distribution in a region ? How to analyse their pattern ? Such are the two main questions discussed in this paper which tries to give an answer by a progress in five steps : thinking about the choice of indicators, thinking about the choice of the spatial scale, making or not a distinction between industrial hranchs or types, integreting or not the temporal changes, testing a typology. Through all the images that have been produced, the relativity of the points of view as well as their partial approach of the studying phenomenon are showed, which indicates that both « prudence » and « modesty » are necessary in all researchs trying to analyse the structures of the territories. [less ▲]

Detailed reference viewed: 74 (17 ULg)
Full Text
Peer Reviewed
See detailSize-related predation reduces intramorph competition in paedomorphic Alpine newts
Denoël, Mathieu ULg; Joly, Pierre

in Canadian Journal of Zoology (2001), 79(6), 943-948

Evolutionary theory assumes that facultative paedomorphosis in newts and salamanders is adaptive in allowing either a younger age at maturity or resource partitioning between the heterochronic morphs. In ... [more ▼]

Evolutionary theory assumes that facultative paedomorphosis in newts and salamanders is adaptive in allowing either a younger age at maturity or resource partitioning between the heterochronic morphs. In newt populations that only take the metamorphic ontogenetic pathway, juveniles are terrestrial and avoid food competition with larvae and breeding adults. In contrast, in populations where paedomorphosis occurs, branchiate newts of all sizes coexist in the aquatic habitats, posing the question of whether intramorph competition exists and its relationship with the evolution of paedomorphosis. We studied size-related predation in such a size-structured community of branchiate Alpine newts (Triturus alpestris) inhabiting a deep alpine lake. Although gape limitation may explain such size-related predation, individuals also exhibited selectivity according to prey size. Amongst small prey that were within the capture range of all newt size classes, smaller newts preyed on smaller items than did larger ones. We assume that such decisions favour the coexistence of different-sized individuals. It is suspected that such size-selective predation on items which are avoided by water-living metamorphs allows the maintenance of facultative paedomorphosis, in favouring resource partitioning between morphs. [less ▲]

Detailed reference viewed: 196 (9 ULg)
Peer Reviewed
See detailCell turnover in BLV-infected sheep.
Debacq, C.; Peremans, T.; Kerkhofs, P. et al

in AIDS Research and Human Retroviruses (2001), 17(1), 13

Detailed reference viewed: 11 (1 ULg)
Full Text
Peer Reviewed
See detailThe effect of food on growth and metamorphosis of paedomorphs in Triturus alpestris apuanus
Denoël, Mathieu ULg; Poncin, Pascal ULg

in Archiv für Hydrobiologie (2001), 152(4), 661-670

The effect of food level on growth and metamorphosis of paedomorphs was examined in an experimental replicated design in Triturus alpestris apuanus. Paedomorphosis concerns the retention of larval ... [more ▼]

The effect of food level on growth and metamorphosis of paedomorphs was examined in an experimental replicated design in Triturus alpestris apuanus. Paedomorphosis concerns the retention of larval characteristics in adult individuals. Newts that forgo metamorphosis and then retain gill and gill slits in the adult stage maintain an aquatic life but keep potential for undergoing metamorphosis. Paedomorphs metamorphosed later in treatments with food as a non-limiting factor than in stressful treatments where food was limited. Timing of metamorphosis did not differ between males and females. Food level greatly affected growth rates. These results confirm and extend optimality models that predict paedomorphosis under advantageous aquatic conditions (paedomorph advantage hypothesis) and metamorphosis in stressful aquatic habitats. [less ▲]

Detailed reference viewed: 259 (14 ULg)
Peer Reviewed
See detailL'etude clinique du mois. L'etude CALM ou interet de combiner un inhibiteur de l'enzyme de conversion et un antagoniste du recepteur de type 1 de l'angiotensine II dans le traitement de la nephropathie diabetique.
Philips, Jean-Christophe ULg; Weekers, Laurent ULg; Scheen, André ULg

in Revue Médicale de Liège (2001), 56(2), 126-8

The main objective of the CALM (Candesartan And Lisinopril Microalbuminuria) study is to assess the effect of a dual blockade of the renin-angiotensin system--using both an angiotensin converting enzyme ... [more ▼]

The main objective of the CALM (Candesartan And Lisinopril Microalbuminuria) study is to assess the effect of a dual blockade of the renin-angiotensin system--using both an angiotensin converting enzyme inhibitor (ACE-I) and an angiotensin II type 1 receptor blocker--in patients with type 2 diabetes, high blood pressure and microalbuminuria. The study included 200 patients randomized to receive candesartan 16 mg or lisinopril 20 mg for 12 weeks, followed by 12 weeks of the same monotherapy or a combination treatment. Main outcomes are the reduction of microalbuminuria and blood pressure. All three of the treatments are effective, but the dual blockade is respectively 18%, 8 mmHg and 5 mmHg more effective in reducing microalbuminuria, systolic and diastolic blood pressure. No comparison is made between this "new" association and the more frequently used biotherapy (i.e. ACE-I plus thiazidic diuretic) and therefore its usefulness in regular practice is still to be determined. [less ▲]

Detailed reference viewed: 170 (0 ULg)
Peer Reviewed
See detailSubclinical cerebellar impairment in the common types of migraine: a three-dimensional analysis of reaching movements.
Sandor, P. S.; Mascia, A.; Seidel, L. et al

in Annals of Neurology (2001), 49(5), 668-72

Mutations in the CACNA1A gene can cause familial hemiplegic migraine (FHM) and/or cerebellar ataxia CACNA1A codes for the alpha1 subunit of P/Q-Ca2+ channels and is highly expressed in the cerebellum ... [more ▼]

Mutations in the CACNA1A gene can cause familial hemiplegic migraine (FHM) and/or cerebellar ataxia CACNA1A codes for the alpha1 subunit of P/Q-Ca2+ channels and is highly expressed in the cerebellum. Using a pointing paradigm and infrared optoelectronic tracking system, we found subclinical hypermetria and other subtle cerebellar signs in the common forms of migraine. These were more pronounced in migraine with than without aura. Whether this reflects involvement of Ca2+ channel genes in the common types of migraine needs to be investigated by genetic analyses. [less ▲]

Detailed reference viewed: 26 (2 ULg)
Full Text
Peer Reviewed
See detailProcollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis.
Fernandes, R. J.; Hirohata, S.; Engle, J. M. et al

in Journal of Biological Chemistry (2001), 276(34), 31502-9

The amino and carboxyl propeptides of procollagens I and II are removed by specific enzymes as a prerequisite for fibril assembly. Null mutations in procollagen I N-propeptidase (ADAMTS-2) cause ... [more ▼]

The amino and carboxyl propeptides of procollagens I and II are removed by specific enzymes as a prerequisite for fibril assembly. Null mutations in procollagen I N-propeptidase (ADAMTS-2) cause dermatosparaxis in cattle and the Ehlers-Danlos syndrome (dermatosparactic type) in humans by preventing proteolytic excision of the N-propeptide of procollagen I. We have found that procollagen II is processed normally in dermatosparactic nasal cartilage, suggesting the existence of another N-propeptidase(s). We investigated such a role for ADAMTS-3 in Swarm rat chondrosarcoma RCS-LTC cells, which fail to process the procollagen II N-propeptide. Stable transfection of RCS-LTC cells with bovine ADAMTS-2 or human ADAMTS-3 partially rescued the processing defect, suggesting that ADAMTS-3 has procollagen II N-propeptidase activity. Human skin and skin fibroblasts showed 30-fold higher mRNA levels of ADAMTS-2 than ADAMTS-3, whereas ADAMTS-3 mRNA was 5-fold higher than ADAMTS-2 mRNA in human cartilage. We propose that both ADAMTS-2 and ADAMTS-3 process procollagen II, but ADAMTS-3 is physiologically more relevant, given its preferred expression in cartilage. The findings provide an explanation for the sparing of cartilage in dermatosparaxis and, perhaps, for the relative sparing of some procollagen I-containing tissues. [less ▲]

Detailed reference viewed: 14 (0 ULg)
Peer Reviewed
See detailMigraine
Sandor, Peter S.; Agosti, Reto; Schoenen, Jean ULg

in Pain Clinical Updates (2001), 9

Detailed reference viewed: 26 (4 ULg)
Full Text
See detailDes escargots et des champignons à la rescousse du développement durable
Libois, Roland ULg; Codjia, J.T.C.

in Parcs & Réserves (2001), 56(4), 46-49

Detailed reference viewed: 21 (3 ULg)
Full Text
Peer Reviewed
See detailInfluence du régime d’administration continu ou discontinu d’acétate de nomégestrol sur l’apoptose des cellules mammaires
Van den Brule, F; DESREUX, Joëlle ULg; BELIARD, Aude ULg et al

in Reproduction Humaine et Hormones (2001), 15

Detailed reference viewed: 23 (1 ULg)
Peer Reviewed
See detailContrebande de cigarettes: un exemple moderne de délinquance d'entreprise
Dantinne, Michaël ULg

in Revue Internationale de Criminologie et de Police Technique et Scientifique [= RICPTS] (2001), (1), 3-25

Detailed reference viewed: 99 (9 ULg)
Full Text
See detailUne enquête internationale sur l'éducation à la citoyenneté : Connaissances, représentations, attitudes et engagement des jeunes
Lafontaine, Annette ULg; Hindryckx, Geneviève ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 59-64

Detailed reference viewed: 48 (5 ULg)
Peer Reviewed
See detailAnticyclonic eddies in the deep eastern Black Sea in summer-autumn 1999 (satellite and ship-borne observations
Ginzburg, Anna I.; Zatsepin, Andrey; Kostianoy, Andrey G. et al

in Earth Observation and Remote Sensing (2001), 5

Detailed reference viewed: 29 (7 ULg)
Full Text
Peer Reviewed
See detailA comparison of the efficacy and tolerability of meloxicam and diclofenac in the treatment of patients with osteoarthritis of the lumbar spine.
Valat, J P; Accardo, S; REGINSTER, Jean-Yves ULg et al

in Inflammation Research (2001), 50(Suppl 1), 30-4

OBJECTIVE: The aim of this study was to evaluate the efficacy and tolerability of meloxicam compared with diclofenac in patients with osteoarthritis of the lumbar spine. SUBJECTS: 229 patients with ... [more ▼]

OBJECTIVE: The aim of this study was to evaluate the efficacy and tolerability of meloxicam compared with diclofenac in patients with osteoarthritis of the lumbar spine. SUBJECTS: 229 patients with radiologically confirmed osteoarthritis of the lumbar spine. TREATMENT AND METHODS: Once-daily meloxicam 7.5 mg tablet or diclofenac 100 mg slow release tablet. Efficacy and tolerability parameters were assessed at baseline and after 3, 7 and 14 days of treatment. RESULTS: The two drugs had equal short-term efficacy, with pain on motion of lumbar spine significantly (p<0.05) decreased at Day 3. Secondary efficacy variables were also significantly improved at Days 3, 7 and 14. There were no statistically significant differences between the two drugs, although the global tolerability of meloxicam was significantly better than for diclofenac, as assessed by the investigators (p = 0.0072) and the patients (p = 0.049). CONCLUSIONS: Meloxicam and diclofenac were equivalent in relieving the acute pain associated with osteoarthritis of the lumbar spine. However, meloxicam was much better tolerated. [less ▲]

Detailed reference viewed: 27 (3 ULg)
Peer Reviewed
See detailComparison of deposition images obtained by use of an ultrafine 99m-technetium-labeled carbon dry aerosol with ventilation images obtained by use of 81m-krypton gas for evaluation of pulmonary dysfunction in calves.
Votion, Dominique ULg; Coghe, J. D.; Lekeux, Pierre ULg

in American Journal of Veterinary Research (2001), 62(12), 1881-6

OBJECTIVE: To characterize the accuracy of an ultrafine 99m-technetium-labeled carbon dry aerosol for use in assessment of regional ventilation in calves with pulmonary dysfunction. ANIMALS: 7 Belgian ... [more ▼]

OBJECTIVE: To characterize the accuracy of an ultrafine 99m-technetium-labeled carbon dry aerosol for use in assessment of regional ventilation in calves with pulmonary dysfunction. ANIMALS: 7 Belgian White and Blue calves. PROCEDURE: The ultrafine aerosol was assessed by comparing deposition (D) images with ventilation (V) images obtained by use of 81 m-krypton (81mKr) gas via D-to-V ratio (D:V) image analysis in calves during spontaneous breathing (SB) and during experimentally induced pulmonary dysfunction (ePD). RESULTS: Mismatching index (LrTot) calculated on the D:V images revealed a good match (LrTot, 0.96 +/- 0.01) between D and V distribution patterns in calves during SB. Calculation of the ultrafine aerosol penetration index relative to 81mKr (PIRel) revealed preferential distribution of the ultrafine aerosol in lung parenchyma (PIRel, 1.13 +/- 0.11). In ePD, heterogeneity in the D:V distribution was observed (LrTot, 0.78 +/- 0.10) as a result of ultrafine aerosol particles impaction in airways as indicated by PIRel (0.66 +/- 0.16) and a proportion of pixels more radioactive in D images, compared with V images, that was located in the central part of the lung (475 +/- 77% in ePD vs 32.8 +/- 5.7% in SB). However, this central deposition did not prevent visual examination of the entire ventilated lung. CONCLUSIONS AND CLINICAL RELEVANCE: The ultrafine aerosol appears suitable for use in examination of ventilated parts of lungs of cattle, even those with impaired pulmonary function. However, airway impaction of ultrafine aerosol particles impedes the quantification of regional ventilation in cattle with abnormal lung function. [less ▲]

Detailed reference viewed: 43 (6 ULg)
Peer Reviewed
See detailExtended analysis of the spectrum of triply-ionozed Ytterbium (Yb IV) and transition probabilities
Wyart, J.-F.; Tchang-Brillet, W. U. L.; Spector, N. et al

in Physica Scripta (2001), 63

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailModification génétique de la levure Yarrowia lipolytica pour maîtriser la β-oxydation
Waché, Y.; Aguedo, Mario ULg; LeDall, M.-T. et al

in Journal de la Société de Biologie (2001), 195(4), 459-459

Les biotechnologies font régulièrement appel à la β-oxydation pour produire des composés à haute valeur ajoutée ou dépolluer des effluents industriels. Cette voie métabolique est difficile à maîtriser car ... [more ▼]

Les biotechnologies font régulièrement appel à la β-oxydation pour produire des composés à haute valeur ajoutée ou dépolluer des effluents industriels. Cette voie métabolique est difficile à maîtriser car elle implique un nombre réduit d'enzymes pour une voie très longue. En particulier, la production d'intermédiaires réactionnels est délicate car les enzymes de la voie de reconsommation sont souvent les mêmes que celles impliquées dans la production. Ainsi, la production de γ-décalactone à partir de ricinoléate de méthyle chez Y. lipolytica implique la β-oxydation (Endrizzi et al., 1996). Cette levure est un bon modèle pour étudier le métabolisme des acides gras car elle possède cinq acyl-CoA oxydases (Aox) catalysant la première étape de la β-oxydation (Wang et al., 1999). L'effet d'une invalidation des gènes codant pour les Aox a été étudié sur la production de γ-décalactones. En fonction des Aox présentes dans les souches, différentes lactones sont produites et leur reconsommation peut être nettement ralentie. Cette étude montre qu'on peut maîtriser la β-oxydation en modifiant le matériel génétique des souches et qu'on peut ainsi améliorer les productions existantes mais aussi produire de nouvelles molécules d'intérêt. [less ▲]

Detailed reference viewed: 33 (0 ULg)
Peer Reviewed
See detailEvidence of rainbow trout prolactin interaction with its receptor through unstable homodimerisation.
Le Rouzic, Philippe; Sandra, Olivier; Grosclaude, Jeanne et al

in Molecular & Cellular Endocrinology (2001), 172(1-2), 105-13

This study aims to characterise Prolactin receptor (PRLR) in rainbow trout for which no information is available despite the availability of Salmonid PRL preparations. By screening a freshwater rainbow ... [more ▼]

This study aims to characterise Prolactin receptor (PRLR) in rainbow trout for which no information is available despite the availability of Salmonid PRL preparations. By screening a freshwater rainbow trout intestine cDNA library with a probe corresponding to the extracellular domain (ECD) of tilapia PRLR, we have cloned a 2.5 kb insert coding for the PRLR. The mature protein of 614 amino acid residues is similar to PRLR isolated in tilapia and also the long form of mammalian PRLR. Analysis of PRLR gene expression in osmoregulatory organs revealed the presence of a unique transcript, thus confirming the involvement of this hormone in the control of osmoregulation in this fish species. By using surface plasmon resonance (SPR) technology, kinetic measurement of interaction between trout PRL and its receptor ECD was studied. This approach allowed us to demonstrate the formation of a transient, unstable homodimeric complex. This unstability could explain the inability to perform binding experiments using homologous PRL. In contrast, heterologous lactogenic ligands were able to interact through a more stable complex. Whether these characteristics of PRL-receptor interaction in rainbow trout are different to what occurs in tilapia where a homologous radioreceptor assay was developed would require further studies. [less ▲]

Detailed reference viewed: 49 (2 ULg)
Peer Reviewed
See detailOptimisation des arcs paraboliques et en chaînette – aide à la conception sur base d'indicateurs morphologiques
Latteur, Pierre ULg; Samyn, Philippe; De Wilde, Patrick

in Revue Française de Génie Civil (2001), 5

Detailed reference viewed: 33 (0 ULg)
Full Text
Peer Reviewed
See detailMonitoring biologique des greffes de cellules souches hématopoïétiques
GOTHOT, André ULg

in Focus Diagnostica (2001), 9

Detailed reference viewed: 9 (1 ULg)
Full Text
Peer Reviewed
See detailDissipative forces and external resonances
Jancart, Sylvie ULg; Lemaitre, Anne

in Celestial mechanics and Dynamical Astronomy (2001), 81

We analyze the process of resonance trapping due to Poynting-Robertson drag and Stokes drag in the frame of the restricted 3-body problem and in the case of external mean motion resonances. The numerical ... [more ▼]

We analyze the process of resonance trapping due to Poynting-Robertson drag and Stokes drag in the frame of the restricted 3-body problem and in the case of external mean motion resonances. The numerical simulations presented are computed by using the 3-dimensional extended Schubart averaging (ESA) integrator developed by Moons (1994) for all mean motion resonances. We complete it by adding the contributions of the dissipative forces. To follow the philosophy of the initial integrator, we average the drag terms, but we do not make any expansion in series of eccentricity or inclination. We show our results, especially capture around asymmetric equilibria, and compare them to those found by Beaué and Ferraz-Mello (1993, 1994) and Liou et al. (1979). [less ▲]

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailCorrect regimen of fluoride and calcium reduces the risk of vertebral fractures in postmenopausal osteoporosis
Reginster, Jean-Yves ULg; Rovati, L; Setnikar, I

in Osteoporosis International (2001), 12

Detailed reference viewed: 13 (3 ULg)
Full Text
Peer Reviewed
See detailSuboptimal Enhancer Sequences Are Required For Efficient Bovine Leukemia Virus Propagation In Vivo: Implications For Viral Latency
Merezak, C.; Pierreux, C.; Adam, E. et al

in Journal of Virology (2001), 75(15),

Detailed reference viewed: 13 (1 ULg)
Full Text
Peer Reviewed
See detailRegime alimentaire du Grand-Duc du désert, Bubo ascalaphus, dans la réserve naturelle de Mergueb (M'Sila, Algérie)
Biche, Mohamed; Sellami, Medhi; Libois, Roland ULg et al

in Alauda (2001), 69(4), 554-557

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical ... [more ▼]

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical basis (82 %) as well as in term of biomass (96 %) was Meriones shawi trouessarti (Gerbillidae). Other preys included Jaculus orientalis (Dipodidae), and two insectivores: Crocidura russula and Hemiechinus aethiopicus. Among the avifauna, only the Spanish sparrow (Passer hispaniolensis) was a significant part of the Eagle owl dietn especially in spring. Arthropods were represented by Scarabeidae in spring and Scorpionidae in summer but they played a minor role in the food of the Eagle owl. The originality of this diet lies in the absence of Brown hare (Lepus capensis) and the presence of only one specimen of the desert hedgehog. Although its food spectrum was very narrow in this site, the Eagle owl can be regarded as opportunistic as it concentrated on the most available prey: Meriones shawi. [less ▲]

Detailed reference viewed: 330 (5 ULg)
Full Text
Peer Reviewed
See detailPresentation of a French version ot the Internal, Personal and Situational Attributions Questionnaire
Laroi, Frank ULg; Brédart, Serge ULg

in European Review of Applied Psychology = Revue Européenne de Psychologie Appliquée (2001), 52

In recent years an increasing interest in attributional style in both normal and pathological populations has developed. In that context, the Internal, Personal and Situational Attributions Questionnaire ... [more ▼]

In recent years an increasing interest in attributional style in both normal and pathological populations has developed. In that context, the Internal, Personal and Situational Attributions Questionnaire (IPSAQ) was constructed. We investigated the psychometric properties of a French translation of the IPSAQ in a normal population.The results offer evidence that the present french translation has similarly adequate psychometric porperties as the original english version [less ▲]

Detailed reference viewed: 252 (14 ULg)
Full Text
Peer Reviewed
See detailThe early Paleozoic carbon cycle
Godderis, Y.; François, Louis ULg; Veizer, J.

in Earth And Planetary Science Letters (2001), 190(3-4), 181-196

A review of O, C, Sr and S isotope trends for the entire Phanerozoic shows that the present-day values of isotope signals are similar to those at the Proterozoic termination. The sharp rise in Sr-87/Sr-86 ... [more ▼]

A review of O, C, Sr and S isotope trends for the entire Phanerozoic shows that the present-day values of isotope signals are similar to those at the Proterozoic termination. The sharp rise in Sr-87/Sr-86 since similar to 65 Ma has been attributed to an uplift and subsequent metamorphism and erosion associated with the Himalayas and Tibet. This orogenic evolution has been postulated to have influenced the global organic and inorganic carbon cycles and climate as well. A similar large-scale orogeny, the Pan-African event, also dominated the Neoproterozoic (Vendian) times, and the similarity of modern and Neoproterozoic isotope values for seawater may therefore have had a comparable tectonic cause. In this contribution, we present the results of a numerical model of the coupled C-alkalinity-S-Sr cycles suggesting that the early Paleozoic (from early Cambrian to late Devonian) evolution of Sr, O, C and S seawater isotope signals could have been the consequence of progressive oxidation of a large reduced carbon reservoir exhumed during the Pan-African orogeny. The delta O-18 measured in brachiopod shells is used as a forcing of the model, postulating that any change in the oxygen isotopic composition of seawater is the result of a disequilibrium in the organic carbon subcycle through the coupling of the oxygen isotopic and carbon cycles. The calculated delta C-13, Sr-87/Sr-86 and delta S-34 are in good agreement with the data, as is the reasonable calculated history for atmospheric pCO(2) and its relation to global climate. (C) 2001 Elsevier Science B.V. All rights reserved. [less ▲]

Detailed reference viewed: 18 (0 ULg)
Full Text
Peer Reviewed
See detailPerspectives de vaccination anti-dermatophytique chez les carnivores domestiques
Descamps, F.; Brouta, F.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (2001), 145

Detailed reference viewed: 12 (1 ULg)
Peer Reviewed
See detailThe Secret History of Belgian Surrealism
Delville, Michel ULg

in Samizdat (2001)

Detailed reference viewed: 51 (1 ULg)
Full Text
Peer Reviewed
See detailLow TSH requirement and goiter in transgenic mice overexpressing IGF-1 and IGF-1R in the thyroid gland
Clément, S.; Refetoff, S.; Robaye, B. et al

in Endocrinology (2001), 142(12), 5131-5139

Through the cAMP signaling pathway, TSH stimulates thyroid follicular cell proliferation, differentiation, and function. Although the autocrine production of IGF-I in the thyroid gland suggests an ... [more ▼]

Through the cAMP signaling pathway, TSH stimulates thyroid follicular cell proliferation, differentiation, and function. Although the autocrine production of IGF-I in the thyroid gland suggests an important physiological function for this factor in these processes, the exact role of the IGF-I/IGF-I receptor system in vivo remains unclear. Although the mitogenic action of TSH requires the presence of IGF-I or insulin in primary culture of dog and human thyroid cells, IGF-I has an effect equal to and independent of the effect of TSH on cell proliferation in rat thyroid cell lines and may even be the main growth regulator in this case. To investigate the in vivo function of the IGF-I/IGF-I receptor system, transgenic mice overexpressing human IGF-I, IGF-I receptor, or both in the thyroid were generated. Adult transgenic mice did not present external signs of thyroid dysfunction, but mice overexpressing both transgenes had significantly increased gland weight and follicular lumen area. A decreased TSH level together with a slightly increased serum T4 concentration and increased thyroidal iodine uptake were also observed, suggesting that IGF-I and IGF-I receptor stimulate thyroid function to some extent in vivo [less ▲]

Detailed reference viewed: 63 (8 ULg)