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See detailBelgian-style Human Resource Management: A Case of Mistaken Identity
Claus, Lisbeth; Vloeberghs, Daniel; Pichault, François ULg

in European Management Journal (2002), 20(4), 438-446

Discusses various forces that affect the future of human resource management (HRM) in Belgium. Development of HRM in the country; Specific forces that have shaped the development and character of HRM ... [more ▼]

Discusses various forces that affect the future of human resource management (HRM) in Belgium. Development of HRM in the country; Specific forces that have shaped the development and character of HRM; Details of the condition of HRM in the country. [less ▲]

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See detailSyndrome du canal lent associe a une translocation autosomique 2q31-9p27.
Zeevaert, Bernard ULg; Hansen, Isabelle ULg; Crielaard, Jean-Michel ULg et al

in Revue Neurologique (2002), 158(5 Pt 1), 605-8

A 27-year-old man complained of cervicoscapular and forearm weakness and amyotrophy. Electromyographic evaluation showed neuromuscular transmission dysfunction and a repetitive compound muscle action ... [more ▼]

A 27-year-old man complained of cervicoscapular and forearm weakness and amyotrophy. Electromyographic evaluation showed neuromuscular transmission dysfunction and a repetitive compound muscle action potential to a single stimulus. Prostigmine did not improve neuromuscular transmission. The genetic analysis of the patient's lymphocytes demonstrated a chromosomic 2q31-9p27 translocation. The combination of the clinical and electrophysiological data as well as the lack of auto-immunity signs against neuromuscular junction constituents led to the diagnosis to congenital postsynaptic myasthenic syndrome also called slow channel syndrome. This congenital myasthenic syndrome is for the first time associated with an autosomal translocation 2q31-9p27. [less ▲]

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See detailInfo-congres. Prevention du diabete de type 2 chez le sujet obese: premiers resultats avec l'orlistat dans l'etude XENDOS.
Scheen, André ULg

in Revue Médicale de Liège (2002), 57(9), 617-21

The results of the XENDOS study were presented by Professor Lars Sjostrom (Gothenburg, Sweden), on August 26, 2002, at the 9th International Congress on Obesity in Sao Paulo, Brazil. XENDOS (XENical in ... [more ▼]

The results of the XENDOS study were presented by Professor Lars Sjostrom (Gothenburg, Sweden), on August 26, 2002, at the 9th International Congress on Obesity in Sao Paulo, Brazil. XENDOS (XENical in the prevention of Diabetes in Obese Subjects) is a multicentre, randomised, double-blind, placebo-controlled, parallel-group prospective study performed in Sweden over a period of 4 years. The aim of XENDOS was to investigate the use of a weight loss agent (orlistat, Xenical) compared with lifestyle changes for the prevention of type 2 diabetes in obese patients (body mass index > or = 30 kg/m2). Weight loss was greater in the orlistat group (-6.9 kg; n = 1.640) than in the placebo group (-4.1 kg; n = 1.637; p < 0.001). Such a difference in weight reduction was sufficient to significantly reduce the cumulative incidence of type 2 diabetes (6.2% versus 9.0%; p = 0.0032; relative risk reduction of 37.3%). The difference was especially remarkable in obese patients with impaired glucose tolerance (21% of the cohort), with a reduction of conversion to diabetes from 28.8% in the placebo group to 18.8% in the orlistat group (p < 0.005) and a number needed to treat to avoid one event of 11 only. Significant and sustained reductions in cardiovascular risk factors such as arterial blood pressure and lipid levels were also observed in the orlistat group as compared to the placebo group. XENDOS is the first study demonstrating that an antiobesity agent, like orlistat, is able to reduce the progression to diabetes in obese subjects as compared with lifestyle changes alone. [less ▲]

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See detailThe photorefractive effect at large modulation depth in semiconductors with multiple defect levels
Nguyen, Ngoc Duy ULg; Schmeits, Marcel ULg

in Applied Physics B : Lasers & Optics (2002), 74

The photorefractive effect in semiconducting mate- rials with multiple defects is studied in the case of modulation depth m = 1. The basic equations are Poisson's equation and the continuity equations for ... [more ▼]

The photorefractive effect in semiconducting mate- rials with multiple defects is studied in the case of modulation depth m = 1. The basic equations are Poisson's equation and the continuity equations for electrons, holes and occupied defect levels. They include all recombination and optical generation mechanisms between the defect levels and valence and conduc- tion bands. Their explicit numerical solution yields microscopic quantities such as space- and time-dependent electrical field profiles, carrier concentrations, as well as generation and re- combination rates. The fundamental Fourier component of the electric field yields the two-wave-mixing gain. Application is made for InP with two levels in the forbidden gap, for which steady-state and transient resulting quantities are shown. The re- sulting features at large modulation depth are of non-sinusoidal shape. Due to the complexity of the system, the final results strongly depend on all parameters intervening in the models used, as is illustrated for several typical cases. [less ▲]

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See detailContinuité de la délinquance entre l’adolescence et l’âge adulte
Born, Michel ULg

in Criminologie (2002), 35(1), 53-67

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See detailPerspectives de dialogue entre des neuromédiateurs et les kératinocytes.
Pierard-Franchimont, Claudine ULg; Faska, N.; Nikkels, Arjen ULg et al

in Dermatologie Actualité (2002), 65

Les neuromédiateurs contrôlant l’activité de l’axe hypothalamo-hypophysaire sont aussi exprimés dans la peau. D’autres neuromédiateurs liés au stress le sont également. En fait, près d’une vingtaine de ... [more ▼]

Les neuromédiateurs contrôlant l’activité de l’axe hypothalamo-hypophysaire sont aussi exprimés dans la peau. D’autres neuromédiateurs liés au stress le sont également. En fait, près d’une vingtaine de ces molécules sont synthétisées in situ et sont connues pour avoir des récepteurs spécifiques et exprimer une activité biologique dans cet organe. Certaines exercent un impact fonctionnel sur les kératinocytes. Il s’agit en fait de systèmes paracrines neuro-kératinocytaires et autocrines par lesquels les kératinocytes expriment de nombreux récepteurs pour les neuromédiateurs qu’ils libèrent eux-mêmes. [less ▲]

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See detailPrediction of selectivity for enantiomeric separations of uncharged compounds by capillary electrophoresis involving dual cyclodextrin systems
Abushoffa, Adel M.; Fillet, Marianne ULg; Hubert, Philippe ULg et al

in Journal of Chromatography. A (2002), 948(1-2), 321-9

The single-isomer polyanionic cyclodextrin (CD) derivative heptakis-6-sulfato-beta-cyclodextrin (HSbetaCD) has been tested as chiral additive for the enantioseparation of non-steroidal anti-inflammatory ... [more ▼]

The single-isomer polyanionic cyclodextrin (CD) derivative heptakis-6-sulfato-beta-cyclodextrin (HSbetaCD) has been tested as chiral additive for the enantioseparation of non-steroidal anti-inflammatory drugs, such as fenoprofen, flurbiprofen, ibuprofen and ketoprofen, in capillary electrophoresis, using a pH 2.5 phosphoric acid-triethanolamine buffer in the reversed polarity mode. In most cases, the enantiomers of these acidic compounds, present in uncharged form at that pH, were only poorly resolved with HSbetaCD alone. However, the use of HSbetaCD in combination with the neutral CD derivative, heptakis-(2,3,6-tri-O-methyl)-beta-cyclodextrin (TMbetaCD), which has a particularly high enantioselectivity towards these compounds, has led to complete enantioresolution in reasonably low migration times in most cases. Affinity constants for the enantiomers with the two cyclodextrins were determined, using linear regression in a two-step approach. Affinity constants with the charged HSbetaCD were first calculated in single systems while those with the neutral TMbetaCD were determined in dual systems. Selectivity for the enantiomeric separation of these compounds in dual CD systems could be predicted using recently developed mathematical models. [less ▲]

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See detailSaussure entre deux épistémologies
Badir, Sémir ULg

in Le français moderne (2002), 70(2), 231-238

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See detailQuel statut pour l'embryon et le foetus dans le champ juridique belge?
Leleu, Yves-Henri ULg; Langenaken, Evelyne ULg

in Journal des Tribunaux (2002)

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See detailUn diabete peut en cacher un autre.
Scheen, André ULg

in Revue Médicale de Liège (2002), 57(5), 267-9

The abrupt interruption of insulin therapy in a severely obese diabetic woman submitted to a protein-sparing modified fast in a metabolic ward led to a severe ketoacidosis. This complication occurred ... [more ▼]

The abrupt interruption of insulin therapy in a severely obese diabetic woman submitted to a protein-sparing modified fast in a metabolic ward led to a severe ketoacidosis. This complication occurred because the patient had type 1 rather than type 2 diabetes, and the diagnosis of ketoacidosis was delayed because of confusion between ketonuria resulting from insulin deprivation and ketonuria associated with carbohydrate and energy restriction. This case report illustrates the danger of accepting an apparently obvious diagnosis which might be in fact erroneous. More particularly, it points out the importance of a correct differential diagnosis between C-peptide positive insulin-requiring type 2 diabetes and C-peptide negative (insulin-dependent) type 1 diabetes. [less ▲]

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See detailCommunication et langage chez les animaux.
Poncin, Pascal ULg; Huynen, Marie-Claude ULg; Ruwet, J.Cl.

in Bulletin de la Société Royale des Sciences de Liège (2002), 4

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See detailMigration between States and Markets (Conference Report)
Martiniello, Marco ULg

in International Migration Review (2002), 36(2), 593-596

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See detailIdentification of bioindicator species among Ephemeroptera, Plecoptera and Trichoptera in a survey of streams belonging to the rhithral classification in the Grand Duchy of Luxembourg
Dohet, A.; Dolisy, D.; Hoffmann, L. et al

in Verhandlungen der Internationalen Vereinigung für Theoretische und Angewandte Limnologie = Proceedings of the International Association of Theoretical and Applied Limnology (2002), 28

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See detailLes Parents maltraités
Malchair, Alain ULg

in Neurone (2002), 7(3), 83-86

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See detailElevated atmospheric CO2 in open top chambers increases net nitrification and potential denitrification
Carnol, Monique ULg; Hogenboom, L.; Jach, M. E. et al

in Global Change Biology (2002), 8

The control of soil nitrogen (N) availability under elevated atmospheric CO2 is central to predicting changes in ecosystem carbon (C) storage and primary productivity. The effects of elevated CO2 on ... [more ▼]

The control of soil nitrogen (N) availability under elevated atmospheric CO2 is central to predicting changes in ecosystem carbon (C) storage and primary productivity. The effects of elevated CO2 on belowground processes have so far attracted limited research and they are assumed to be controlled by indirect effects through changes in plant physiology and chemistry. In this study, we investigated the effects of a 4-year exposure to elevated CO2 (ambient + 400 mumol mol(-1) ) in open top chambers under Scots pine (Pinus sylvestris L) seedlings on soil microbial processes of nitrification and denitrification. Potential denitrification (DP) and potential N-2 O emissions were significantly higher in soils from the elevated CO2 treatment, probably regulated indirectly by the changes in soil conditions (increased pH, C availability and NO3 (-) production). Net N mineralization was mainly accounted for by nitrate production. Nitrate production was significantly larger for soil from the elevated CO2 treatment in the field when incubated in the laboratory under elevated CO2 (increase of 100%), but there was no effect when incubated under ambient CO2 . Net nitrate production of the soil originating from the ambient CO2 treatment in the field was not influenced by laboratory incubation conditions. These results indicate that a direct effect of elevated atmospheric CO2 on soil microbial processes might take place. We hypothesize that physiological adaptation or selection of nitrifiers could occur under elevated CO2 through higher soil CO2 concentrations. Alternatively, lower microbial NH4 assimilation under elevated CO2 might explain the higher net nitrification. We conclude that elevated atmospheric CO2 has a major direct effect on the soil microbial processes of nitrification and denitrification despite generally higher soil CO2 concentrations compared to atmospheric concentrations. [less ▲]

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See detailRate coefficient determination in charge transfer reactions
Vaeck, Nathalie; Baloïtcha, Ezinvy; Desouter, Michèle ULg et al

in International Journal of Molecular Sciences (2002), 3

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See detailGenetic variation and evolution in the genus Apodemus (Muridae : Rodentia)
Filippucci, M. G.; Macholan, M.; Michaux, Johan ULg

in Biological Journal of the Linnean Society (2002), 75(3), 395-419

Genetic variation was studied using protein electrophoresis of 28-38 gene loci in 1347 specimens of Apodemus agrarius, A. peninsulac, A. flavicollis, A. sylvaticus, A. alpicola, A. uralensis, A. cf ... [more ▼]

Genetic variation was studied using protein electrophoresis of 28-38 gene loci in 1347 specimens of Apodemus agrarius, A. peninsulac, A. flavicollis, A. sylvaticus, A. alpicola, A. uralensis, A. cf. hyrcanicus, A. hermonensis, A. m. mystacinus and A. in. epimelas, representing 121 populations from Europe, the Middle East, and North Africa. Mean values of heterozygosity per locus for each species ranged from 0.02 to 0.04. Mean values of Nei's genetic distance (D) between the taxa ranged from 0.06 (between A. flavicollis and A. alpicola) to 1.34 (between A. uralensis and A. agrarius). The highest values of D were found between A. agrarius and other Apodemus species (0.62-1.34). These values correspond to those generally observed between genera in small mammals. Our data show that A. agrarius and A. peninsulae are sister species, well-differentiated from other taxa. High genetic distance between A. m. mystacinus and A. m. epimelas leads us to consider them distinct species and sister taxa to other Western Palaearctic species of the subgenus Sylvaemus. The data also suggest a recent separation of members of the latter group from a common ancestor, and subsequent rapid radiation, making it difficult to infer phylogenetic relationships. Some taxonomic implications of the results are discussed further. (C) 2002 The Linnean Society of London. [less ▲]

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See detailThe effect of health related quality of life on reported use of health care resources in patients with osteoarthritis and rheumatoid arthritis: a longitudinal analysis.
Ethgen, Olivier ULg; Kahler, Kristijan H; Kong, Sheldon X et al

in Journal of Rheumatology (2002), 29(6), 1147-55

OBJECTIVE: In today's cost conscious environment, health services researchers are consistently trying to find ways to predict future health care resource utilization (HCRU) and its associated costs. We ... [more ▼]

OBJECTIVE: In today's cost conscious environment, health services researchers are consistently trying to find ways to predict future health care resource utilization (HCRU) and its associated costs. We evaluated the impact of health related quality of life (HRQL) on future HCRU in patients with arthritis. METHODS: A total of 642 patients with rheumatoid arthritis (RA) and 395 patients with osteoarthritis (OA) completed at least 2 and as many as 6 consecutive surveys at 6 mo intervals. Information collected included demographics, HRQL questionnaires [Medical Outcome Study Short Form 36 (SF-36), Western Ontario McMaster Universities Osteoarthritis Index (WOMAC), and the Stanford Health Assessment Questionnaire (HAQ)], and HCRU over the previous 6 months. Longitudinal data analysis was perfomed to assess the effect of HRQL on future HCRU. RESULTS: Statistically significant associations between HCRU and HRQL variables were noted. Higher rates of HCRU were found in those in the worst quarter compared with those in the best quarter of HRQL. With the HAQ, OA and RA patients in the worst quarter reported a 199% (p < 0.05) and 48% (p < 0.05) increase in rheumatologist visits, respectively. With the WOMAC Function, increases were as high as 196% (p < 0.05) in rheumatologist visits for patients with OA. Patients with RA with a high level of HRQL as measured by the SF-36 (physical component score) reported a decrease of 31% (p < 0.01) in general practitioner visits and a decrease of 52% (p < 0.01) in hospitalization (mental component score). CONCLUSION: These findings suggest that HRQL may be used to predict future health care consumption. Such an approach may lead to a more efficient allocation of resources by providing useful information to health care providers and health care decision makers. [less ▲]

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See detailLe médicament du mois. Le tacrolimus topique (Protopic).
Pierard, Gérald ULg; Pierard, Claudine ULg; Paquet, Philippe ULg

in Revue Médicale de Liège (2002), 57(8), 552-5

Tacrolimus is a potent inhibitor of immune mechanisms. It belongs to the macrolactam group. It inhibits the release of both Th1 and Th2 cytokines. It proves to be efficacious after topical application in ... [more ▼]

Tacrolimus is a potent inhibitor of immune mechanisms. It belongs to the macrolactam group. It inhibits the release of both Th1 and Th2 cytokines. It proves to be efficacious after topical application in the treatment of atopic dermatitis. In this indication, tacrolimus challenges topical corticosteroids. Irritation risks are present. The local immuno-depression can boost disseminated infections including herpes. The risk to promote photocarcinogenesis on the long term, and that bound to chronic resorption remain theoretical concerns that have not been assessed so far. [less ▲]

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See detailFirst-principles computation of material properties: the ABINIT software project
Gonze, X.; Beuken, J. M.; Caracas, R. et al

in Computational Materials Science (2002), 25(3), 478-492

The density functional theory (DFT) computation of electronic structure, total energy and other properties of materials, is a field in constant progress. In order to stay at the forefront of knowledge, a ... [more ▼]

The density functional theory (DFT) computation of electronic structure, total energy and other properties of materials, is a field in constant progress. In order to stay at the forefront of knowledge, a DFT software project can benefit enormously from widespread collaboration, if handled properly. Also, modern software engineering concepts can considerably ease its development. The ABINIT project relies upon these ideas: freedom of sources, reliability, portability, and self-documentation are emphasised, in the development of a sophisticated plane-wave pseudopotential code. We describe ABINITv3.0, distributed under the GNU General Public License. The list of ABINITv3.0 capabilities is presented, as well as the different software techniques that have been used until now: PERL scripts and CPP directives treat a unique set of FORTRAN90 source files to generate sequential (or parallel) object code for many different platforms; more than 200 automated tests secure existing capabilities; strict coding rules are followed; the documentation is extensive, including online help files, tutorials, and HTML-formatted sources. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailReconstruction of healthcare in Afghanistan.
Porignon, Denis ULg; Hennart, Philippe

in Lancet (2002), 359(9311), 1071-2

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See detailLa recherche scientifique en Hautes-Fagnes
Streel, Maurice ULg

in Bulletin de l'Académie Royale des Sciences, des Lettres et des Beaux-Arts de Belgique. Sciences (2002), XIII(1-6), 55-65

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See detailLe contrat de rivière au service de la politique européenne de l'eau.
Rosillon, Françis ULg; Vander Borght, Paul ULg

in Wallonie (2002), (72), 88-97

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See detailOrigine du Solutréen: le rôle de l'Espagne
Otte, Marcel ULg; Noiret, Pierre ULg

in Zephyrus (2002), LV

The Solutrean "culture" of France should be separated in two clearly distinct elements. (1) The "Proto-Solutrean" and the "early" Solutrean are linked to the late phases of the Gravettian of the northern ... [more ▼]

The Solutrean "culture" of France should be separated in two clearly distinct elements. (1) The "Proto-Solutrean" and the "early" Solutrean are linked to the late phases of the Gravettian of the northern plains. (2) The "middle and late" Solutrean seem to have originated in Spain. A movement from North Africa, in the most arid phase, constitutes the most likely hypothesis to explain this expansion. [less ▲]

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See detailMétabolisme des lipides chez la levure: catabolisme peroxysomal des acides gras et applications biotechnologiques
Waché, Y.; Aguedo, Mario ULg; Nicaud, J.M. et al

in Regard sur la Biochimie (2002), 4

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See detailEvaluation of ocean model ventilation with CFC-11: comparison of 13 global ocean models
Dutay, J.-C.; Bullister, J. L.; Doney, S. C. et al

in Ocean Modelling (2002), 4(2), 89-120

We compared the 13 models participating in the Ocean Carbon Model Intercomparison Project (OCMIP) with regards to their skill in matching observed distributions of CFC-11. This analysis characterizes the ... [more ▼]

We compared the 13 models participating in the Ocean Carbon Model Intercomparison Project (OCMIP) with regards to their skill in matching observed distributions of CFC-11. This analysis characterizes the abilities of these models to ventilate the ocean on timescales relevant for anthropogenic CO2 uptake. We found a large range in the modeled global inventory (+/- 30\%), mainly due to differences in ventilation from the high latitudes. In the Southern Ocean, models differ particularly in the longitudinal distribution of the CFC uptake in the intermediate water, whereas the latitudinal distribution is mainly controlled by the subgrid-scale parameterization. Models with isopycnal diffusion and eddy-induced velocity parameterization produce more realistic intermediate water ventilation. Deep and bottom water ventilation also varies substantially between the models. Models coupled to a sea-ice model systematically provide more realistic AABW formation source region; however these same models also largely overestimate AABW ventilation if no specific parameterization of brine rejection during sea-ice formation is included. In the North Pacific Ocean, all models exhibit a systematic large underestimation of the CFC uptake in the thermocline of the subtropical gyre, while no systematic difference toward the observations is found in the subpolar gyre. In the North Atlantic Ocean, the CFC uptake is globally underestimated in subsurface. In the deep ocean, all but the adjoint model, failed to produce the two recently ventilated branches observed in the North Atlantic Deep Water (NADW). Furthermore, simulated transport in the Deep Western Boundary Current (DWBC) is too sluggish in all but the isopycnal model, where it is too rapid. (C) 2002 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailTraite des êtres humains : un coup de frein à l'application de l'article 77bis de la loi du 15 décembre 1980 ?
Monville, Pierre ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2002)

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See detailMaladie de Horton et atteintes arterielles extratemporales: utilite de la tomographie par emission de positons au 18FDG. A propos de trois observations et d'une revue de la litterature
Belhocine, Tarik; Kaye, Olivier; Delanaye, Pierre ULg et al

in Revue de Médecine Interne (2002), 23(7), 584-91

PURPOSE: We report three cases of Horton's disease, in which F18-Fluorine-2-Deoxy-D-Glucose (18FDG) positron emission tomography (PET) demonstrated a clinically unsuspected extra-cranial vessels ... [more ▼]

PURPOSE: We report three cases of Horton's disease, in which F18-Fluorine-2-Deoxy-D-Glucose (18FDG) positron emission tomography (PET) demonstrated a clinically unsuspected extra-cranial vessels hypermetabolism. METHODS: Fully corrected whole-body PET was performed in three patients (two women, one man) for exploring a marked inflammatory syndrome. Scanning was acquired 60 min after i.v. injection of 222 MBq of 18FDG in average. RESULTS: In two patients with histologically proven Horton's disease, PET alone showed increased glucose metabolism involving the carotid and sub-clavian arteries as well as the ascending aorta, aortic arch, thoracic and abdominal aorta, and the iliac and femoral arteries. In the third patient, by detecting cervical, thoracic and abdominal vessel hypermetabolism, PET non-invasively contributed to the diagnosis of giant cell arteritis. All patients had complete clinical and biological response to corticoids. PET controls performed 3- to 6-months post-treatment, confirmed the disappearance of the metabolic stigma. CONCLUSION: 18FDG PET may show an increased glucose metabolism in asymptomatic extracranial vessels locations of Horton's arterities. If these observations are confirmed on controlled trials, PET could be particularly useful for non-invasive diagnosing, staging and monitoring atypical clinical forms of Horton's disease. The metabolic imaging could also contribute to a better understanding of the pathogenesis of GCA. [less ▲]

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See detailLes privatisations d'entreprises publiques en économie de marché: quelques observations juridiques
Thirion, Nicolas ULg

in Chroniques de Droit Public = Publiekrechtelijke Kronieken (2002), 2

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See detailFracture prevention in postmenopausal women.
Bruyère, Olivier ULg; Edwards, John; Reginster, Jean-Yves ULg

in Clinical Evidence (2002), 8

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See detailModelled glacial and non-glacial HCO3-, Si and Ge fluxes since the LGM: little potential for impact on atmospheric CO2 concentrations and a potential proxy of continental chemical erosion, the marine Ge/Si ratio
Jones, Ian W; Munhoven, Guy ULg; Tranter, Martyn et al

in Global and Planetary Change (2002), 33(1-2), 139-153

The runoff and riverine fluxes of HCO3-, Si and Ge that arise from chemical erosion in non-glaciated terrain, are modelled at six time steps from the Last Glacial Maximum (LGM) to the present day. The ... [more ▼]

The runoff and riverine fluxes of HCO3-, Si and Ge that arise from chemical erosion in non-glaciated terrain, are modelled at six time steps from the Last Glacial Maximum (LGM) to the present day. The fluxes that arise from the Great Ice Sheets are also modelled. Terrestrial HCO3- fluxes decrease during deglaciation, largely because of the reduction in the area of the continental shelves as sea level rises. The HCO3- fluxes. and the inferred consumption of atmospheric CO2 are used as inputs to a carbon cycle model that estimates their impact on atmospheric CO2 concentrations ((CO2)-C-atms). A maximum perturbation of (CO2)-C-atms by similar to 5.5 ppm is calculated, The impact of solutes from glaciated terrain is small in comparison to those from non-glaciated terrain. Little variation in terrestrial Si and Ge fluxes is calculated (< 10%). However, the global average riverine Ge/Si ratio may be significantly perturbed if the glacial Ge/Si ratio is high. At present. variations in terrestrial chemical erosion appear to have only a reduced impact on (CO2)-C-atms and only little influence on the global Si and Ge cycle and marine Ge/Si ratios during deglaciation. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailEffect of some insecticides on acetylcholinesterase from beneficial insects: Coccinella septempunctata, Chrysoperla carnea and Forficula auricularia
Boszic, Andras; Francis, Frédéric ULg; Gaspar, Charles et al

in Med. Fac. Landbouw. Univ. Gent (2002), 67(3), 671-677

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See detailEchouage de mammifères marins : guide d'intervention et procédures d'autopsie
Jauniaux, Thierry ULg; Garcia-Hartmann, M.; Haelters, J. et al

in Annales de Médecine Vétérinaire (2002), 146(5, OCT-NOV), 261-276

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See detailLa mesure de la pression artérielle : écueils et chausse-trapes
Rorive, Georges ULg; Dubois, Bernard ULg; Saint-Remy, Annie ULg

in Revue Médicale de Liège (2002), 57(5), 250-252

La mesure de la pression artérielle est probablement l'acte médical le plus souvent réalisé et certainement un des moins fiables. L'introduction de la mesure ambulatoire de la pression artérielle a permis ... [more ▼]

La mesure de la pression artérielle est probablement l'acte médical le plus souvent réalisé et certainement un des moins fiables. L'introduction de la mesure ambulatoire de la pression artérielle a permis d'identifier l'importance de l'effet consultatio et, par là, de définir l'hypertension de "la blouse blanche". Celle-ci se définit comme une pression artérielle pathologique à la consultation et strictement normale en dehors. Si on la définit de cette manière, cette pathologie ne s'accompagne pas d'une augmentation de la fréqunce des affections cardiovasculaires. Chez un tiers des patients, cependant, elle évolue vers des formes plus sévères de l'hypertension. [less ▲]

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See detailUse of specific bioluminescent cell lines for the detection of steroid hormone (ant)agonists in meat producing animals
Willemsen, Philippe; Scippo, Marie-Louise ULg; Maghuin-Rogister, Guy ULg et al

in Analytica Chimica Acta (2002), 473(1-2), 119-126

We present stable transformed human mammary cell lines displaying highly inducible steroid receptor-mediated luciferase reporter gene expression. The utilization of a cell-based assay for detection of ... [more ▼]

We present stable transformed human mammary cell lines displaying highly inducible steroid receptor-mediated luciferase reporter gene expression. The utilization of a cell-based assay for detection of steroid agonists and antagonists down to 0.3 ng g(-1) is described and its application to the analysis of bovine samples is discussed. In particular, the use of the assays to detect illegal progesterone or androgen treatment has to take into account the presence of natural endogenous hormones. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailLa conformation bouchère des agneaux. Etude d'après la variabilité génétique entre races
Laville, E.; Bouix, J.; Sayd, T. et al

in INRA Productions Animales (2002), 15(1), 53-66

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See detailLes-Bons-Villers, l'église Saint-Martin à Mellet
Hoffsummer, Patrick ULg

in Bulletin de la Fondation Vanhove-Vonneche (2002), 4

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See detailCaractérisation physico-chimique de gommes végétales exsudées par quelques acacias du Burkina Faso
Djiré, O.; Ntema, P.; Zgoulli, S. et al

in Science et Technique (2002), 25(2), 37-47

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See detailTexture characterization of ultramacroporous materials using non-destructive methods
Blacher, Silvia ULg; Maquet, Véronique; Léonard, Angélique ULg et al

in Studies in Surface Science and Catalysis (2002), 158

Image analysis, impedance spectroscopy and X-ray microtomography have been used as non-destructive methods in order to characterize ultramacroporous materials (pore width > 1 mum). These methods are used ... [more ▼]

Image analysis, impedance spectroscopy and X-ray microtomography have been used as non-destructive methods in order to characterize ultramacroporous materials (pore width > 1 mum). These methods are used to investigate the texture of different kinds of materials, i.e., highly oriented polylactide (PLA) foams prepared by freeze-drying, isotropic polyolefin foams prepared by thermal degradation of a chemical foaming agent and convective heat dried wastewater sludges. The image analysis of SEM micrographs recorded at different magnifications gave information on the pore size distribution and pore morphology. Impedance spectroscopy was used to investigate the transport properties of the three-dimensional porous matrices by measurement of the water ionic conduction. Finally, 3D image reconstruction from 2D cross-sections obtained by X-ray microtomography allowed visualizing the pore structure. [less ▲]

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See detailVegetation composition of a threatened hypersaline lake (Lake Bardawil), North Sinai
El-Bana, M I; Khedr, A-H A; Van Hecke, P et al

in Plant Ecology (2002), 163(1), 63-75

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See detailLes antagonistes calciques ont-ils une place de première ligne dans le traitement de l'hypertension artérielle?
Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2002), 57(2), 79-84

During the nineties, a controversy was noted in the literature about the potential risk of using calcium antagonists in the treatment of hypertension. Several recent studies, such as the INSIGHT’s one ... [more ▼]

During the nineties, a controversy was noted in the literature about the potential risk of using calcium antagonists in the treatment of hypertension. Several recent studies, such as the INSIGHT’s one have not confirmed this provided that one uses long-acting molecule. But the real beneficial effect due to the different antihypertensive classes is mainly linked to the magnitude of the blood pressure lowering effect. [less ▲]

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See detailThe Otherness of Self. A Genealogy of the Self in Contemporary China
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2002), Volume XIV

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See detailElectrical characterization of InGaN/GaN multiple-quantum-well structures by thermal admittance spectroscopy
Nguyen, Ngoc Duy ULg; Schmeits, Marcel; Germain, Marianne et al

in Physica Status Solidi C. Current Topics in Solid State Physics (2002)

Experimental results of electrical characterization of InGaN/GaN multiple-quantum-well electrolu- minescence test structures obtained by thermal admittance spectroscopy are presented. The stu- died GaN ... [more ▼]

Experimental results of electrical characterization of InGaN/GaN multiple-quantum-well electrolu- minescence test structures obtained by thermal admittance spectroscopy are presented. The stu- died GaN : Mg/5 × (InGaN/GaN)/GaN:Si structures were grown on c-plane sapphire substrate by metal-organic vapor phase epitaxy. Admittance measurements were conducted from room tem- perature down to 125 K for a wide frequency range and for different applied bias voltages. Analy- sis of the capacitance versus frequency curves shows the presence of several cutoff frequencies which originate from the response of equivalent RC series circuits and give peaks in the conduc- tance divided by angular frequency. The dependence of the position and the amplitude of these peaks on temperature is discussed. [less ▲]

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See detailStatut et tendances des effectifs d’éléphants dans les aires protégées de l’Est du Burkina Faso
Bouché, Philippe ULg; Lungren, Clark; Ouédraogo, Léonard

in Pachyderm (2002), 32

Le Burkina Faso abrite l’effectif d’éléphants de savane le plus important de toute l’Afrique de l’Ouest, là où cette espèce jouit d’une protection intégrale. Un recensement aérien par échantillon a été ... [more ▼]

Le Burkina Faso abrite l’effectif d’éléphants de savane le plus important de toute l’Afrique de l’Ouest, là où cette espèce jouit d’une protection intégrale. Un recensement aérien par échantillon a été mené dans le sud-est du Burkina Faso en avril et mai 2000. L’effectif total moyen atteignait 1.743 ± 648 éléphants, ce qui constitue la plus grande population d’éléphants de savane en Afrique de l’Ouest. La moyenne des groupes observés était de: 5,42 (Erreur standard = 11,68 animaux) (1 à 32 individus / groupe). La distribution des éléphants enregistrée confirme largement la distribution enregistrée les années précédentes. [less ▲]

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See detailThe plant pathogenesis-related PR-10 proteins
Elbez, Mounira; Kevers, Claire ULg; Hamdi, Saïd et al

in Acta Botanica Gallica : Bulletin de la Société Botanique de France (2002), 149(4), 415-444

The PR-10 protein family contains proteins related to pathogenesis and allergenic proteins. They are acidic proteins, with an intracellular localization, usually members of a multigene family and ... [more ▼]

The PR-10 protein family contains proteins related to pathogenesis and allergenic proteins. They are acidic proteins, with an intracellular localization, usually members of a multigene family and ubiquitous among plant kingdom. They contain a highly conserved motif, identified as a phosphate binding site. Even if the biological function of these proteins is still unknown, many indicators seem to favour the hypothesis of an RNAse activity. Moreover, one of them seems to be a cytokinin specific binding protein. Besides, PR-10 protein expression induction under cytokinin treatment was observed with the Catharanthus roseus CrPR-10a protein. Here, we present the evidence of a significative increase of endogenous cytokinin contents in leaves of transgenic Tobacco plants over-expressing the CrPR-10a protein. [less ▲]

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See detailIsolement et caractérisation de l'ostéocalcine équine
Carstanjen, Bianca; Wattiez, R.; Amory, Hélène ULg et al

in Annales de Médecine Vétérinaire (2002), 146

Equine bone gamma-carboxyglutamic acid containing protein - also called osteocalcin - has been isolated for the first time till homogeneity. After acid demineralisation and acid extraction, the ... [more ▼]

Equine bone gamma-carboxyglutamic acid containing protein - also called osteocalcin - has been isolated for the first time till homogeneity. After acid demineralisation and acid extraction, the purification procedure was based on reverse phase chromatography, gel filtration and ion exchange chromatography. The amino acid sequence of the primary structure has been determined to be YLDHWLGA(HYP) APYPDPL(GLA)PRR(GLA)VC (GLA)LNPDCDELADHIGF-AYRRFYGPV. The protein has a calculated molecular weight of 5,732 kDa and a calculated isoelectric point of 4,45. It contains 49 amino acids, from which 3 are gamma-carboxyglutamic acid residues at position 17, 21 and 24 and has a fully hydroxylated proline in position nine and cysteine in position 23 and 29. Equine osteocalcin shows a strong homology with bovine (98%), ovine (96%) and human (94%) osteocalcin [less ▲]

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See detailAxillary artery injury secondary to anterior shoulder dislocation: report of two cases.
MAWEJA, Sylvie ULg; SakalihasanN, Natzi ULg; VAN DAMME, Hendrik ULg et al

in Acta Chirurgica Belgica (2002), 102(3), 187-91

Vascular injuries secondary to isolated shoulder dislocation are rare. Unawareness for closed axillary artery trauma by many physicians treating shoulder dislocations, counts often for missed or delayed ... [more ▼]

Vascular injuries secondary to isolated shoulder dislocation are rare. Unawareness for closed axillary artery trauma by many physicians treating shoulder dislocations, counts often for missed or delayed diagnosis. The authors describe two cases that presented with an anterior shoulder dislocation, complicated by a disruption of the axillary artery with subsequent thrombosis. The various pathogenic mechanisms are discussed. The pathognomic triad consists of anterior shoulder dislocation, absent or diminished distal pulse and an axillary protruding hematoma. Prompt surgical arterial repair is mandatory. [less ▲]

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See detailStudy of the structural, electronic, and magnetic properties of the barium-rich iron(IV) oxides, Ba2FeO4 and Ba3FeO5
Delattre, J. L.; Stacy, A. M.; Young, V. G. et al

in Inorganic Chemistry (2002), 41(11), 2834-2838

Crystals of Ba2FeO4 and Ba3FeO5, grown from a "self-sealing" KOH-Ba(OH)(2) flux, have been characterized by single-crystal X-ray diffraction, Mossbauer spectroscopy, and magnetic measurements. Ba2FeO4 ... [more ▼]

Crystals of Ba2FeO4 and Ba3FeO5, grown from a "self-sealing" KOH-Ba(OH)(2) flux, have been characterized by single-crystal X-ray diffraction, Mossbauer spectroscopy, and magnetic measurements. Ba2FeO4 forms nonmerohedral twinned crystals with the monoclinic space group P2(1)/c, a = 6.034(2) Angstrom, b = 7.647(2) Angstrom, c = 10.162(3) Angstrom, beta = 92.931(6)degrees, and Z = 4. Ba3FeO5 crystallizes in the orthorhombic space group Pnma, with a = 10.301(1) Angstrom, b = 8.151(1) Angstrom, c = 7.611(1) Angstrom, and Z = 4. While both compounds feature discrete FeO44- tetrahedra, the anion found in Ba2FeO4 has shorter Fe-O bonds and is significantly distorted relative to the Ba3FeO5 anion, An iron valence of 4+ was confirmed by magnet susceptibility measurements and by the low-temperature isomer shifts of -0.152 and -0.142 mm/s relative to alpha-iron for Ba2FeO4 and Ba3FeO5, respectively. [less ▲]

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See detailYBa2Cu3O7 tapes prepared by sol-gel deposition techniques: microstructure and structural characterizations
Marguillier, David ULg; Cloots, Rudi ULg; Rulmont, André ULg et al

in Physica C: Superconductivity (2002), 372(Part 2), 715-718

We report on the preparation conditions of YBa2Cu3O7 polycrystalline superconducting tapes by a sol-gel deposition technique. We present some discussion on the compatibility between the nature of the ... [more ▼]

We report on the preparation conditions of YBa2Cu3O7 polycrystalline superconducting tapes by a sol-gel deposition technique. We present some discussion on the compatibility between the nature of the substrate, the use of a buffer layer, and the conditions used to prepare appropriate superconducting YBa2Cu3O7,, materials. We report also on the microstructural characterizations performed in order to evaluate the crystallites size, degree of orientation and connectivity. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailPetite réflexion sur la qualité du bois d'épicéa
Hebert, Jacques ULg; Herman, Marc; Jourez, Benoît ULg

in Forêt Wallonne (2002), (60), 24-25

En termes de qualité du bois, l'influence du sylviculteur est déterminante. En effet, dès la décision de plantation, et ensuite, par le jeu des soins culturaux et des éclaircies, il va façonner, compte ... [more ▼]

En termes de qualité du bois, l'influence du sylviculteur est déterminante. En effet, dès la décision de plantation, et ensuite, par le jeu des soins culturaux et des éclaircies, il va façonner, compte tenu des conditions environnementales, les caractéristiques de la matière première qui en définiront les aptitudes technologiques. [less ▲]

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See detailMultidisciplinary study of the Wealden deposits in the Mons Basin (Belgium): a progress report.
Yans, J; Spagna, P; Foucher, JC et al

in Aardkungigen Mededelingen (2002), 12

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See detailEnquête sur les "contes" de Voltaire
Tilkin, Françoise ULg

in Cahiers Voltaire : Revue Annuelle de la Société Voltaire (2002), 1

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See detailExperimental Validation Of The Constant Level Method For Identification Of Non-Linear Multi-Degree-Of-Freedom Systems
Dimitriadis, Grigorios ULg

in Journal of Sound & Vibration (2002), 258(5), 829-845

System identification for non-linear dynamical systems could find use in many applications such as condition monitoring, finite element model validation and determination of stability. The effectiveness ... [more ▼]

System identification for non-linear dynamical systems could find use in many applications such as condition monitoring, finite element model validation and determination of stability. The effectiveness of existing non-linear system identification techniques is limited by various factors such as the complexity of the system under investigation and the type of non-linearities present. In this work, the constant level identification approach, which can identify multi-degree-of-freedom systems featuring any type of non-linear function, including discontinuous functions, is validated experimentally. The method is shown to identify accurately an experimental dynamical system featuring two types of stiffness non-linearity. The full equations of motion are also extracted accurately, even in the presence of a discontinuous non-linearity. [less ▲]

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See detailMise au point d'un modèle cartographique pour la description des stations forestières en Ardenne belge.
Claessens, Hugues ULg; Lejeune, Philippe ULg; Cuvelier, M. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2002), 6(4), 209-220

The paper presents an original method dealing with the forest site types delineation. The suggested method consists in integrating a typological key in a GIS aiming at producing a thematic map that ... [more ▼]

The paper presents an original method dealing with the forest site types delineation. The suggested method consists in integrating a typological key in a GIS aiming at producing a thematic map that describes forest site types. Data used are the soil map of Belgium (digitized at the scale 1:20,000) and a digital elevation model built from a topographic map (scale 1:10,000). The typological key is mainly based on the methodology used by Thill et al. (1988) in the site types system for central Ardenne, the potential vegetation map of Sougnez and Dethioux (1975) and the ecoregion map of Delvaux and Galoux (1962). In that respect, site types are closely linked to the soil map and the phytosociological classification. So, they can be connected to the afforestation guide and different phytosociological and autecological studies concerning forest species. It is then possible to map the potential habitats or the site potentialities related to tree species. The key is valid for the Ardenne ecoregion located in Southern Belgium (elevation higher than 300 m). It has to be validated through an intensive use in the field, taking into account its imprecision linked to the types of collected data, chieffly those being digitized. The integration of such a tool in a SIG can be considered as an original way in terms of integrated forest management or forest sites description in the context of the project “Natura 2000” launched by the European Union. The study has been carried out within the framework of an experimental integrated management project concerning the Saint-Hubert forest (17,000 ha). [less ▲]

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See detailLes acteurs et les enjeux au coeur de l'évaluation
Vandoorne, Chantal ULg

in Education santé (2002), 173(173), 9-11

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See detailFrontal hypometabolism does not explain inhibitory dysfunction in Alzheimer disease
Collette, Fabienne ULg; Van der Linden, Martial ULg; Delrue, Gaël ULg et al

in Alzheimer Disease and Associated Disorders (2002), 16(4, Oct-Dec), 228-238

A series of tasks assessing inhibitory processes was administered to patients with Alzheimer disease and control subjects. Two groups of patients with Alzheimer disease were examined: patients with ... [more ▼]

A series of tasks assessing inhibitory processes was administered to patients with Alzheimer disease and control subjects. Two groups of patients with Alzheimer disease were examined: patients with hypometabolism restricted to the posterior (temporal and parietal) cerebral areas and patients with hypometabolism in both posterior and anterior (frontal) cerebral areas. The performances of the patients with Alzheimer disease were inferior to those of control subjects on all inhibitory tasks, but the two groups of patients obtained similar scores. These data indicate that frontal lobe hypometabolism is not necessary to produce inhibitory impairment in Alzheimer disease. Consequently, inhibitory dysfunction could be the consequence of a (partial) disconnection process between posterior and anterior cerebral areas. [less ▲]

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See detailStress écologique et chronobiologique de la dérive géoclimatique.
Pierard, Sébastien ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Revue Verviétoise d'Histoire Naturelle (2002), 59

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See detailHyperfine structure of neutral vanadium lines and livels
Lefèbvre, P.-H.; Garnir, Henri-Pierre ULg; Biémont, Emile ULg

in Physica Scripta (2002), 66

We have recorded hollow-cathode spectra of neutral vanadium by Fourier transform spectroscopy in the near infrared - visible region (9000-17 000 cm-1). 36 transitions showing hyperfine structure have been ... [more ▼]

We have recorded hollow-cathode spectra of neutral vanadium by Fourier transform spectroscopy in the near infrared - visible region (9000-17 000 cm-1). 36 transitions showing hyperfine structure have been analyzed, allowing us to deduce magnetic dipole constants for 27 levels belonging to the 3d44p and 3d34s4p configurations. For 22 of these levels no data were previously available. [less ▲]

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See detailEtude par spectroscopie de génération de la fréquence somme de l'interface méthanol-platine
Vidal, F.; Busson, B.; Six, C. et al

in J. Phys. IV France (2002), 12

La spectroscopie vibrationnelle non-linéaire par génération de la fréquence somme est une sonde particulièrement adaptée à l'étude des interfaces entre milieux denses. Cette technique a été appliquée à l ... [more ▼]

La spectroscopie vibrationnelle non-linéaire par génération de la fréquence somme est une sonde particulièrement adaptée à l'étude des interfaces entre milieux denses. Cette technique a été appliquée à l'étude de l'interface électrochimique monocristal de platine/solution acide de méthanol, système qui constitue un modèle de pile à combustible, dispositif où l'énergie chimique est directement convertie en énergie électrique. Les propriétés vibrationnelles dépendent fortement de l'orientation cristallographique de l'électrode de platine. [less ▲]

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See detailEnzymatically prepared n-alkyl esters of glucuronic acid: The effect of hydrophobic chain length on surface properties
Blecker, Christophe ULg; Piccicuto, S.; Lognay, Georges ULg et al

in Journal of Colloid & Interface Science (2002), 247(2), 424-428

The effect of hydrophobic chain length on surface properties of enzymatically prepared n-alkyl esters of glucuronic acid are examined. Dynamic parameters from Hua and Rosen's mathematical model and ... [more ▼]

The effect of hydrophobic chain length on surface properties of enzymatically prepared n-alkyl esters of glucuronic acid are examined. Dynamic parameters from Hua and Rosen's mathematical model and equilibrium surface tension are presented for esters with octyl, decyl, dodecyl, and tetradecyl alkyl segments. Increasing the alkyl chain length has a significant influence on the surface activity. Decyl and dodecyl glucuronate exhibit an interesting adsorption speed associated with foaming capacity. Octyl glucuronate exhibits a micellar organization as its bulk concentration is over 10.68 mM. (C) 2002 Elsevier Science (USA). [less ▲]

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See detailLandscape ecology – A top-down approach (J. Sanderson, L.D. Harris)
Bogaert, Jan ULg

in Acta Biotheoretica (2002), 50(2), 129-131

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See detailCompte rendu de R. GODDING, Prêtres en Gaule mérovingienne, Bruxelles, 2001
George, Philippe ULg

in Moyen Age (Le) (2002)

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See detailMedical imaging and MRI in nail disorders: report of 119 cases and review of the literature
Richert, Bertrand ULg; Baghaie, Mahmoud

in Dermatologic Therapy (2002), 15

Radiographs remain the golden standard for exploration of the bony structures located beneath the nail plate, but they provide no information on the perionychium. Until a few years ago the nail apparatus ... [more ▼]

Radiographs remain the golden standard for exploration of the bony structures located beneath the nail plate, but they provide no information on the perionychium. Until a few years ago the nail apparatus was deprived of investigative medical imaging. Glomus tumor was the only condition that was explored using invasive techniques such as angiography or scintigraphy. High-frequency ultrasound rapidly came up against technical limits. High-resolution magnetic resonance imaging (MRI) offers a superior alternative in detection of distal lesions as well as their relationship with the adjacent structures. MRI provides an accurate analysis of the nail apparatus with detection of lesions as small as 1 mm. This noninvasive technique will allow us to better understand, diagnose, and treat pathologies of the distal phalanx. [less ▲]

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See detailA transformed fish cell line expressing a green fluorescent protein-luciferase fusion gene responding to cellular stress
Molina, A.; Carpeaux, Rudy ULg; Martial, Joseph ULg et al

in Toxicology in Vitro (2002), 16(2), 201-7

We obtained a stable transformed fish (EPC) cell line containing a reporter gene under the control of the tilapia HSP70 promoter. Expression of the reporter gene, coding for a green fluorescent protein ... [more ▼]

We obtained a stable transformed fish (EPC) cell line containing a reporter gene under the control of the tilapia HSP70 promoter. Expression of the reporter gene, coding for a green fluorescent protein (GFP)-luciferase fusion protein, was assessed by measuring the luciferase enzymatic activity by luminometry and the GFP expression by fluorescence microscopy and flow cytometry. The clone was characterized for its capacity to respond to heat shock treatment. The results show high induction after 1 h at 37 degrees C of treatment, up to 500-fold. In addition, its convenience to detect a large range of cellular stressors was evaluated. We observed high induction when Cd2+, Zn2+, Hg2+ or Cu2+ was added, but not Pb2+. In addition, activation of the reporter gene was observed in the presence of other compounds such as acetyl chloride, tetrachlorophenol, chloroacetamide and sodium arsenite. In conclusion, this cell line can be used as a rapid, cheap and easy biological test to determine cellular stress induced by environmental pollutants, alone or in conjunction with other, more specific assays. [less ▲]

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See detailDevelopment of a two-color picosecond optical parametric oscillator, pumped by a Nd:YAG laser mode locked using a nonlinear mirror, for doubly-resonant sum frequency generation spectroscopy
Mani, A. A.; Dreesen, Laurent ULg; Humbert, C. et al

in Surface Science (2002), 502-503

We step up a doubly-resonant sum frequency generation (DR-SFG) spectrometer based on the use of an all-solid-state flash-lamp-pumped Nd:YAG laser that synchronously pumps two parametric oscillators ... [more ▼]

We step up a doubly-resonant sum frequency generation (DR-SFG) spectrometer based on the use of an all-solid-state flash-lamp-pumped Nd:YAG laser that synchronously pumps two parametric oscillators. Pulses as short as 12 ps FWHM are generated by mode locking a Nd:YAG oscillator using a frequency doubling nonlinear mirror combined with a two-photon absorber. The available pump power is shared between a LiNbO3/AgGaS2 optical parametric oscillator (OPO), tunable from 3800 to 1100cm-1 and a BBO OPO tunable from 410 to 2600 nm. Spectral resolution and pulse are 2 and 3 cm-1 in the infrared and visible spectral ranges, respectively. First DR-SFG spectra of self-assembled monolayers on Au are presented. [less ▲]

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See detailComposite structures optimization using sequential convex programming
Bruyneel, Michaël ULg; Fleury, Claude ULg

in Advances in Engineering Software (2002), 33(7-10), 697-711

The design of composite structures is considered here. The approximation concepts approach is used to solve the optimization problem. The convex approximations of the MMA family are briefly described ... [more ▼]

The design of composite structures is considered here. The approximation concepts approach is used to solve the optimization problem. The convex approximations of the MMA family are briefly described. Several modifications of these approximations are presented. They are now based on gradient information at two successive iterations, avoiding the use of the expensive second-order derivatives. A two-point fitting scheme is also described, where the function value at the preceding design point is used to improve the approximation. Numerical examples compare these new purely non-monotonous schemes to the existing ones for the selection of optimal fibers orientations in laminates. It is shown how these two-point based approximations are well adapted to the problem and can improve the optimization task, leading to reasonable computational efforts. A procedure is also derived for considering simultaneously monotonous and non-monotonous structural behaviors. The resulting generalized approximation scheme is well suited for the optimization of composite structures when both plies thickness and fibers orientations are considered as design variables. It is concluded that the newly developed approximation schemes of the MMA family are reliable for composite structures optimization. All the studied approximations are convex and separable: the optimization problem can then be solved using a dual approach. (C) 2002 Civil-Comp Ltd and Elsevier Science Ltd. All rights reserved. [less ▲]

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See detail" Entre Notre-Dame de Paris et Chartres : Le portail de Longpont-sur-Orge (vers 1235) "
Kasarska, Iliana ULg

in Bulletin Monumental (2002), 160

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See detailIdentités et transactions réflexives. Une approche de l'identité des acteurs retraités
Vrancken, Didier ULg

in Recherches Sociologiques et Anthropologiques (2002), 2

A partir de l'identification d'une population, celle des retraités âgés entre 50 et 75 ans, population particulièrement confrontée à des problèmes de reconnaissance et d'identités sociales, cet article ... [more ▼]

A partir de l'identification d'une population, celle des retraités âgés entre 50 et 75 ans, population particulièrement confrontée à des problèmes de reconnaissance et d'identités sociales, cet article propose de repenser le concept d'identité en sociologie au départ d'un triple travail d'articulation identitaire qu'accomplirait l'acteur. Après avoir identifié une transaction narrative, une transaction argumentative, l'auteur dégage une troisième forme : celle de la tradition réflexive analysée à la suite de la tradition expressiviste allemande et de son dépassement par la critique herméneutique. C'est de cette triple articulation identitaire que rendrait compte une typologie proposée en conclusion. [less ▲]

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See detailL'intensité des soins en gériatrie : élaboration d'un document de réflexion
Petermans, Jean ULg

in Revue Médicale de Bruxelles (2002), 23

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See detailLipid-Interacting Properties Of The N-Terminal Domain Of Human Apolipoprotein C-III
Lins, Laurence ULg; Flore, Christelle ULg; Chapelle, L. et al

in Protein Engineering (2002), 15(6), 513-20

The lipid-interacting properties of the N-terminal domain of human apolipoprotein C-III (apo C-III) were investigated. By molecular modeling, we predicted that the 6-20 fragment of apo C-III is obliquely ... [more ▼]

The lipid-interacting properties of the N-terminal domain of human apolipoprotein C-III (apo C-III) were investigated. By molecular modeling, we predicted that the 6-20 fragment of apo C-III is obliquely orientated at the lipid/water interface owing to an asymmetric distribution of the hydrophobic residues when helical. This is characteristic of 'tilted peptides' originally discovered in viral fusion proteins and later in various proteins including some involved in lipoprotein metabolism. Since most tilted peptides were shown to induce liposome fusion in vitro, the fusogenic capacity of the 6-20 fragment of apo C-III was tested on unilamellar liposomes and compared with the well characterized SIV fusion peptide. Mutants were designed by molecular modeling to assess the role of the hydrophobicity gradient in the fusion. FTIR spectroscopy confirmed the predominantly helical conformation of the peptides in TFE solution and also in lipid-peptide complexes. Lipid-mixing experiments showed that the apo C-III (6-20) peptide is able to increase the fluorescence of a lipophilic fluorescent probe. The vesicle fusion was confirmed by core-mixing and leakage assays. The hydrophobicity gradient plays a key role in the fusion process because the mutant with no hydrophobic asymmetry but the same mean hydrophobicity as the wild type does not induce significant lipid fusion. The apo C-III (6-20) fragment is, however, less fusogenic than the SIV peptide, in agreement with their respective mean hydrophobicity. Since lipid fusion should not be the physiological function of the N-terminal domain of apo CIII, we suggest that its peculiar distribution of hydrophobic residues is important for the lipid-binding properties of apo C-III and should be involved in apolipoprotein and lipid exchanges crucial for triglyceride metabolism. [less ▲]

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See detailAromatic Side-Chain Interactions In Proteins. I. Main Structural Features
Thomas, Annick ULg; Meurisse, R.; Charloteaux, Benoît ULg et al

in Proteins-Structure Function and Genetics (2002), 48(4), 628-34

In a data set of 593 nonhomologous proteins from the PDB, we have analyzed the pairing of phenylalanine, tyrosine, tryptophan, and histidine residues with their closest aromatic partner. The frequency ... [more ▼]

In a data set of 593 nonhomologous proteins from the PDB, we have analyzed the pairing of phenylalanine, tyrosine, tryptophan, and histidine residues with their closest aromatic partner. The frequency distribution of the shortest interatomic distance of partners is bimodal with a sharp peak at approximately 3.8 A and a wider one at a longer distance. Only the 3.8 A peak corresponds to direct ring-ring interactions thus aromatic pairs. The aromatic pairs were separated into two classes, near-sequence pairs and far-sequence pairs. Near sequence pairs stabilize local structure, and far-sequence pairs stabilize tertiary structure. Far-sequence pairs (74% of all pairs) mainly bridge two beta-strands, followed by pairs that bridge a beta-strand and a helix, and pairs that bridge a beta-strand and a random coil structure. Pairs that bridge helices are rare. The secondary structure of the near-sequence pairs depends on the partner distance in the sequence. When the partners are 1, 3, or 4 residues apart in the sequence, pairs are mostly found in helical structures. When the partners are two apart, pairs are mostly found in the same beta-strand. Analysis of the frequency of near sequence pairs supports the hypothesis that aromatic pairing occurs after, rather than before, the formation of secondary structures. [less ▲]

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See detailStudy of the role of ionogenic amino-acid residues in catalytic activity of thiamine triphosphatase from bovine kidney by means of chemical modification
Makarchikov, Alexander F; Luchko, A. A.; Bettendorff, Lucien ULg et al

in News of Biomedical Sciences (2002), 3

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See detailPourquoi la Finlande a-t-elle tant de jeunes bons lecteurs ?
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2002), 9-10

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See detailLa forêt et la protection du sol dans le cadre d'aménagement forestiers intégrés
Huart, O.; Adam, V.; Quevy, B. et al

in Fiche technique (2002), (14),

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See detailApplication de Pichia anomala souche K, Beta 1,3-glucanes et chlorure de Calcium pour le contrôle des maladies de conservation des pommes en conditions proches de la pratique
Jijakli, Haissam ULg; Dickburt, C.; De Clerck, D. et al

in Colloque transnational sur les luttes biologiques, intégrée et raisonnée (2002)

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See detailPrognosis of hematologic malignancies does not predict intensive care unit mortality.
MASSION, Paul ULg; Dive, Alain M; Doyen, Chantal et al

in Critical Care Medicine (2002), 30(10), 2260-70

OBJECTIVE: To evaluate the correlation between specific prognosis of hematologic malignancies on the one hand and intensive care unit and hospital mortality in critically ill patients with hematologic ... [more ▼]

OBJECTIVE: To evaluate the correlation between specific prognosis of hematologic malignancies on the one hand and intensive care unit and hospital mortality in critically ill patients with hematologic malignancies on the other hand. DESIGN: Observational study during a 10-yr period. SETTING: A 22-bed medical-surgical intensive care unit. PATIENTS: A total of 84 consecutive patients with nonterminal hematologic malignancies with medical complications requiring intensive care. INTERVENTIONS: None. MEASUREMENTS: Demographic factors, acute physiology and organ dysfunction scores, microbiology, therapeutic support, and hematologic factors data on admission and during the intensive care unit stay were collected, together with mortality follow-up. Based on specific-disease prognostic factors and related published survival curves, the prognosis of hematologic malignancies was assessed and defined as good, intermediate, or poor according to a 3-yr survival probability of >50%, 20-50%, or <20%, respectively. MAIN RESULTS: Prognosis of hematologic malignancies does not predict intensive care unit or hospital mortality and almost reaches significance for 6-mo mortality (53%, 71%, and 84% rate for patients with good, intermediate, and poor prognosis, respectively, p =.058), but it determines long-term survival (p =.008). Intensive care unit, hospital, and 6-mo overall mortality rates were 38%, 61%, and 75%, respectively. Using multivariate analysis, intensive care unit mortality was best predicted on admission by respiratory failure and fungal infection, whereas hospital mortality was predicted by the number of organ failures, the bone marrow transplant status, and the presence of fungal infection. The Acute Physiology and Chronic Health Evaluation II and the Simplified Acute Physiology Score II had no prognostic value, whereas the difference of the Multiple Organ Dysfunction Score between at the time of admission and at day 5 allowed quick prediction of hospital mortality. Diseases with the poorest 6-mo prognosis were acute myeloid leukemia and non-Hodgkin lymphoma. CONCLUSION The severity of the underlying hematologic malignancies does not influence intensive care unit or hospital mortality. Short-term prognosis is exclusively predicted by acute organ dysfunctions and by a pathogen's aggressiveness. Therefore, reluctance to admit patients with nonterminal hematologic malignancies to the intensive care unit based only on the prognosis of their underlying hematologic malignancy does not seem justified. [less ▲]

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See detailThe complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription.
Gaudray, Gilles ULg; Gachon, Frederic; Basbous, Jihane et al

in Journal of virology (2002), 76(24), 12813-22

The RNA genome of the human T-cell leukemia virus type 1 (HTLV-1) codes for proteins involved in infectivity, replication, and transformation. We report in this study the characterization of a novel viral ... [more ▼]

The RNA genome of the human T-cell leukemia virus type 1 (HTLV-1) codes for proteins involved in infectivity, replication, and transformation. We report in this study the characterization of a novel viral protein encoded by the complementary strand of the HTLV-1 RNA genome. This protein, designated HBZ (for HTLV-1 bZIP factor), contains a N-terminal transcriptional activation domain and a leucine zipper motif in its C terminus. We show here that HBZ is able to interact with the bZIP transcription factor CREB-2 (also called ATF-4), known to activate the HTLV-1 transcription by recruiting the viral trans-activator Tax on the Tax-responsive elements (TxREs). However, we demonstrate that the HBZ/CREB-2 heterodimers are no more able to bind to the TxRE and cyclic AMP response element sites. Taking these findings together, the functional inactivation of CREB-2 by HBZ is suggested to contribute to regulation of the HTLV-1 transcription. Moreover, the characterization of a minus-strand gene protein encoded by HTLV-1 has never been reported until now. [less ▲]

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See detailDevelopment of GEQUAC as a new group contribution method for strongly non-ideal mixtures
Ehlker, Gerhard H; Pfennig, Andreas ULg

in Fluid Phase Equilibria (2002), 203((1-2)), 53-69

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See detailCoastal and Estuarine Fine Sediment Processes (book review)
Grégoire, Marilaure ULg

in Journal of Marine Systems (2002), 37

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See detailA. Gacek: The Arabic manuscript tradition: A glossary of technical terms and bibliography
Bauden, Frédéric ULg

in Journal of the American Oriental Society (2002), 122(3), 658-659

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See detailControl of the Radical Polymerization by 2,2,15,15-tetramethyl-1-aza-4,7,10,13-tetraoxacyclopentadecan-1-oxyl and its Sodium Salt
Olive, Gilles ULg; Rozanska, Xavier; Smulders, Wilfred et al

in Macromolecular Chemistry and Physics (2002), 203(12), 1790-1796

The control of the radical polymerization of styrene by 2,2,15,15-tetramethyl-1-aza-4,7,10,13-tetraoxacyclopentadecan-1-oxyl is reported here in bulk at 90 °C, 120 °C and in miniemulsion. Similarly, the ... [more ▼]

The control of the radical polymerization of styrene by 2,2,15,15-tetramethyl-1-aza-4,7,10,13-tetraoxacyclopentadecan-1-oxyl is reported here in bulk at 90 °C, 120 °C and in miniemulsion. Similarly, the control by its sodium complex is reported in bulk at 90 °C. [less ▲]

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See detailCyclin-dependent kinase-2 controls oligodendrocyte progenitor cell cycle progression and is downregulated in adult oligodendrocyte progenitors.
Belachew, Shibeshih ULg; Aguirre, Adan A.; Wang, Hang et al

in Journal of Neuroscience (2002), 22(19), 8553-62

Proliferation of oligodendrocyte progenitor (OP) cells is a crucial process controlling myelination in the CNS. Previous studies demonstrated a correlation between OP proliferation rate and cyclin E ... [more ▼]

Proliferation of oligodendrocyte progenitor (OP) cells is a crucial process controlling myelination in the CNS. Previous studies demonstrated a correlation between OP proliferation rate and cyclin E/cyclin-dependent kinase-2 (cdk2) activity. To establish a causal link between cyclin E/cdk2 activity and OP proliferation, we selectively modulated cdk2 activity in vitro by transfection of cultured OP cells. Dominant-negative (Dn)-cdk2 overexpression inhibited mitogen-induced OP cell proliferation, whereas wild-type (wt)-cdk2 prevented cell cycle arrest caused by anti-mitotic signals. Dn-cdk2- or wt-cdk2-mediated regulation of G(1)/S transition, per se, did not influence initiation of OP differentiation. To study the function of cyclin E/cdk2 in OP cells during development in vivo, we analyzed cdk2 and cyclin E expression in cells acutely isolated from transgenic mice expressing the green fluorescent protein (GFP) under the control of the 2'-3'-cyclic nucleotide 3'-phosphodiesterase gene promoter. Both cyclin E/cdk2 protein levels and activity were decreased in GFP(+) oligodendrocyte lineage cells between postnatal days 4 and 30. Immunostaining of NG2(+)/GFP(+) OP cells in brain tissue sections showed a 90% decrease in overall cell proliferation and cdk2 expression between perinatal and adult cells. However, cdk2 expression within the proliferating (i.e., expressing the proliferating cell nuclear antigen) OP cell population was maintained throughout development. Our data indicate that: (1) cyclin E/cdk2 activity plays a pivotal function in OP cell cycle decisions occurring at G(1)/S checkpoint; (2) initiation of OP differentiation is independent of cyclinE/cdk2 checkpoint, and (3) intrinsic differences in cyclin E/cdk2 expression and activity may underlie the slowly proliferative state that characterizes so-called "quiescent" adult OP cells in vivo. [less ▲]

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See detailHormonal measurements in late pregnancy and parturition in dairy cows - possible tools to monitor foetal well being
Kornmatitsuk, B.; Veronesi, M. C.; Madej, A. et al

in Animal Reproduction Science (2002), 72(3-4), 153-164

Three dairy heifers (A, B and C) were induced to parturition with two prostaglandin (PG) F-2alpha injections on day 268 and 269 of pregnancy. Signs of approaching parturition were carefully observed. The ... [more ▼]

Three dairy heifers (A, B and C) were induced to parturition with two prostaglandin (PG) F-2alpha injections on day 268 and 269 of pregnancy. Signs of approaching parturition were carefully observed. The following parameters were registered: degrees of calving difficulty, date and time of parturition, calf's birth weight and calf's sex. Body temperature was measured and blood samples were taken every 3 h 3 days before the first PGF(2alpha) injection until 3 days after parturition. The plasma concentrations of the PGF2a metabolite, progesterone, cortisol, oestrone sulphate and pregnancy associated glycoproteins (PAGs) were analysed. Heifers A, B and C delivered 48, 51 and 57 h after the first PGF(2alpha) injection, respectively. Heifer A delivered without any signs of calving difficulty, whereas, the parturition was considered to be slight and moderate difficulty occurred in the delivery of heifers B and C, respectively. The calf of heifer C, without any abnormal gross-evidences, was stillborn. All animals had retained foetal membranes. A slight increase of the PGF(2alpha) metabolite at the time of parturition was found only in heifer C, whereas the levels dramatically increased in all animals 15-24 h after parturition. At the same time, progesterone levels decreased within 3 h after the first PGF(2alpha) injection (P < 0.05) and reached 0.8, 2.7 and 12.4 nmol/l at the time of parturition in heifers A, B and C, respectively. High release of cortisol at the time of parturition was seen in heifer C. Rising levels of oestrone sulphate around the time of parturition were recorded in all heifers, whereas, increasing levels of PAGs were recorded only in heifer A. In conclusion, the patterns of the PGF(2alpha) metabolite, cortisol, progesterone and PAGs were changed in the cases of calving difficulty and stillbirth after PGF(2alpha)-induction of parturition. However, the relationship between oestrone sulphate and PAGs and the status of foetal well being prior to parturition require further elucidation. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailSynthesis, cytotoxicity, and antiplasmodial and antitrypanosomal activity of new neocryptolepine derivatives.
Jonckers, Tim H M; van Miert, Sabine; Cimanga, Kanyanga et al

in Journal of Medicinal Chemistry (2002), 45(16), 3497-508

On the basis of the original lead neocryptolepine or 5-methyl-5H-indolo[2,3-b]quinoline, an alkaloid from Cryptolepis sanguinolenta, derivatives were prepared using a biradical cyclization methodology ... [more ▼]

On the basis of the original lead neocryptolepine or 5-methyl-5H-indolo[2,3-b]quinoline, an alkaloid from Cryptolepis sanguinolenta, derivatives were prepared using a biradical cyclization methodology. Starting from easily accessible educts, this approach allowed the synthesis of hitherto unknown compounds with a varied substitution pattern. As a result of steric hindrance, preferential formation of the 3-substituted isomers over the 1-substituted isomers was observed when cyclizing N-(3-substituted-phenyl)-N'-[2-(2-trimethylsilylethynyl)phenyl]carbodiimides. All compounds were evaluated for their activity against chloroquine-sensitive as well as chloroquine-resistant Plasmodium falciparum strains, for their activity against Trypanosoma brucei and T. cruzi, and for their cytotoxicity on human MRC-5 cells. Mechanisms of action were investigated by testing heme complexation using ESI-MS, inhibition of beta-hematin formation, DNA interactions (DNA-methyl green assay and linear dichroism), and inhibition of human topoisomerase II. Neocryptolepine derivatives with a higher antiplasmodial activity and a lower cytotoxicity than the original lead have been obtained. This selective antiplasmodial activity was associated with inhibition of beta-hematin formation. 2-Bromoneocryptolepine was the most selective compound with an IC(50) value against chloroquine-resistant P. falciparum of 4.0 microM in the absence of cytotoxicity (IC(50) > 32 microM). Although cryptolepine, a known lead for antimalarials also originally isolated from Cryptolepis sanguinolenta, was more active (IC(50) = 2.0 microM), 2-bromoneocryptolepine showed a low affinity for DNA and no inhibition of human topoisomerase II, in contrast to cryptolepine. Although some neocryptolepine derivatives showed a higher antiplasmodial activity than 2-bromocryptolepine, these compounds also showed a higher affinity for DNA and/or a more pronounced cytotoxicity. Therefore, 2-bromoneocryptolepine is considered as the most promising lead from the present work for new antimalarial agents. In addition, 2-bromo-, 2-nitro-, and 2-methoxy-9-cyanoneocryptolepine exhibited antitrypanosomal activity in the micromolar range in the absence of obvious cytotoxicity. [less ▲]

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See detailMass transfer by free and forced convection from single spherical liquid drops
Waheed, M Adekojo; Henschke, Martin; Pfennig, Andreas ULg

in International Journal of Heat & Mass Transfer (2002), 45(22), 4507-4514

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See detailRestorative Justice: Activities and expectations at European LEvel
Lauwaert, Katrien ULg; Aertsen, Ivo

in Era Forum : Scripta Iuris Europaei (2002)

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See detailControlled radical polymerisation catalysed by ruthenium complexes: Variations on Ru-Cp#
Delfosse, Sébastien; Guillaume, Bernard; Richel, Aurore ULg et al

in Polymer Preprints (2002)

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See detailBlade-Tip Timing Measurement Of Synchronous Vibrations Of Rotating Bladed
Dimitriadis, Grigorios ULg; Carrington, Ian B.; Wright, Jan Robert et al

in Mechanical Systems & Signal Processing (2002), 16(4), 599-622

Blade-tip timing (BTT) is a promising method for the detection, measurement and analysis of blade vibrations in rotating bladed assemblies. However, the intricacies of the method when applied to real ... [more ▼]

Blade-tip timing (BTT) is a promising method for the detection, measurement and analysis of blade vibrations in rotating bladed assemblies. However, the intricacies of the method when applied to real rotating structures undergoing synchronous (Engine Ordered) vibrations are not yet fully understood. In this paper, a mathematical model is developed to simulate data from typical BTT tests of rotating assemblies. The simulator is then used in order to provide a qualitative analysis of several phenomena that can be associated with the synchronous vibrations of rotating assemblies, including mistuning, coupling, excitation at multiple Engine Orders and simultaneous synchronous and asynchronous responses. It is concluded that none of these phenomena on its own will render the identification of the frequency and amplitude of blade vibrations impossible. However, there is no single BTT data analysis method that is able to deal with all of these phenomena. [less ▲]

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See detailCoalescence of secondary dispersions in fiber beds
Speth, Hauke; Pfennig, Andreas ULg; Chatterjee, Michael et al

in Separation and Purification Technology (2002), 29(2), 113-119

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