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See detailPolarization dependence of the exchange energy
Gonze, X.; Ghosez, Philippe ULg; Godby, R. W.

in Physical Review Letters (1997), 78(10), 2029-2029

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See detailLes comportements des enseignants dans la perspective d'un traitement différencié des élèves
Piéron, Maurice; Ledent, Maryse; Pirottin, Véronique et al

in Revue de l'Education Physique (1997), 4

La pédagogie basée sur la théorie des "rythmes d'apprentissage" accorde une place privilégiée à l'individualisation et contredit le principe d'une programmation uniforme, valable pour tous. Toute classe ... [more ▼]

La pédagogie basée sur la théorie des "rythmes d'apprentissage" accorde une place privilégiée à l'individualisation et contredit le principe d'une programmation uniforme, valable pour tous. Toute classe est hétérogène, chaque enfant étant singulier, différent dans ses valeurs, ses attitudes, ses potentialités et ses compétences. Chacun apprend à un rythme différent, plus rapidement que la moyenne dans des domaines, moins rapidement dans d'autres. ... [less ▲]

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See detailThree new species of Opegraphaceae (Lichens) from the Namib desert
Egea, J.M.; Sérusiaux, Emmanuël ULg; Torrente, Pilar et al

in Mycotaxon (1997), 61

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See detailExtensive Ulcerative Colitis and Extraintestinal Manifestations in a Patient with Hiv Infection and Significant Cd4 T-Cell Lymphopenia
Louis, Edouard ULg; Moutschen, Michel ULg; de Marneffe, Pierre et al

in Gastroentérologie Clinique et Biologique (1997), 21(11), 884-7

We report a heterosexual patient with HIV infection and a CD4 T-cell count of 0.45 x 10(9)/L who developed mild ulcerative proctitis, sacroileitis and oligoarthiritis. While he was treated with 5 ... [more ▼]

We report a heterosexual patient with HIV infection and a CD4 T-cell count of 0.45 x 10(9)/L who developed mild ulcerative proctitis, sacroileitis and oligoarthiritis. While he was treated with 5-aminosalicylic enemas, the patient rapidly developed severe pancolitis. An emergency colectomy without procetectomy was performed. A few months later, he suffered recurrence of ulcerative proctitis, aggravation of arthritic pain and developed anterior uveitis. All symptoms disappeared after proctectomy. There was no evidence for opportunistic infection or Kaposi's sarcoma. Antineutrophil cytoplasmic antibodies were positive and the HLA-B27 antigen was present. CD4 counts were lower during the phases of active disease than during remission. This case demonstrates that severe ulcerative colitis can occur in the presence of moderate T-cell defects. In view of a recent report of remission of Crohn's disease under comparable circumstances, it is possible that the extent of T-cell involvement in both diseases is radically different. [less ▲]

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See detailBWGIC guidelines for training and quality control in adult interventional cardiology. Belgian Working Group of Invasive Cardiology.
Legrand, Victor ULg; Vrolix, M.; De Bruyne, B. et al

in Acta cardiologica (1997), 52(6), 507-14

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See detailThe Complete Genome Sequence Of The Gram-Positive Bacterium Bacillus Subtilis
Kunst, F.; Ogasawara, N.; Moszer, I. et al

in Nature (1997), 390(6657), 249-256

Bacillus subtilis is the best-characterized member of the Gram-positive bacteria. Its genome of 4,214,810 base pairs comprises 4,100 protein-coding genes. Of these protein-coding genes, 53% are ... [more ▼]

Bacillus subtilis is the best-characterized member of the Gram-positive bacteria. Its genome of 4,214,810 base pairs comprises 4,100 protein-coding genes. Of these protein-coding genes, 53% are represented once, while a quarter of the genome corresponds to several gene families that have been greatly expanded by gene duplication, the largest family containing 77 putative ATP-binding transport proteins. In addition, a large proportion of the genetic capacity is devoted to the utilization of a variety of carbon sources, including many plant-derived molecules. The identification of five signal peptidase genes, as well as several genes for components of the secretion apparatus, is important given the capacity of Bacillus strains to secrete large amounts of industrially important enzymes. Many of the genes are involved in the synthesis of secondary metabolites, including antibiotics, that are more typically associated with Streptomyces species. The genome contains at least ten prophages or remnants of prophages, indicating that bacteriophage infection has played an important evolutionary role in horizontal gene transfer, in particular in the propagation of bacterial pathogenesis. [less ▲]

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See detailBankfull discharge recurrence interval in gravel bed rivers
Petit, François ULg; Pauquet, A.

in Earth Surface Processes & Landforms (1997)

Bankfull discharge was identified in some 30 gravel-bed rivers representing in total c. 40 gauging stations. The catchment sizes vary from 4km2 to nearly 2700km2. Bankfull discharge values increases with ... [more ▼]

Bankfull discharge was identified in some 30 gravel-bed rivers representing in total c. 40 gauging stations. The catchment sizes vary from 4km2 to nearly 2700km2. Bankfull discharge values increases with basin size. In the case of gravel-bed rivers developed on an impermeable substratum, the following equation emerges: Qb=0·087 A1·044. Bankfull discharge recurrence interval was determined by fitting maximum annual floods (Ta) into Gumbel’s distribution and then using the partial duration series (Tp) in this same distribution. Recurrence interval is below 0·7 years (Tp) for small pebble-bed rivers developed on an impermeable substratum; it reaches 1·1 to 1·5 years when the catchment size of these rivers exceeds 250km2. Rivers incised in the soft schists of the Famenne show larger channel capacity at bankfull stage, a small width/depth ratio and thus higher recurrence intervals (1·4–5·3 years with Ta and 1–4·4 years with Tp). Baseflow-dominated gravel-bed streams and sandy or silty rivers experience less frequent bankfull discharges, with a recurrence interval higher than 2 or even 3 years (Tp). [less ▲]

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See detailA. ANGENENDT, Heilige und Reliquien, Munich, 1994
George, Philippe ULg

in Francia. 1, Mittelalter (1997)

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See detailFatal Massive Liver Steatosis. A Clinicopathological Case Report
de Leval, Laurence ULg; Lambermont, Bernard ULg; D'Orio, Vincenzo ULg et al

in Acta Gastro-Enterologica Belgica (1997), 60(2, Apr-Jun), 180-183

Hepatic fatty change is a common lesion. Two forms are recognized: micro- and macrovesicular steatosis, the former being much less frequent and more serious than the latter. The case of an alcoholic woman ... [more ▼]

Hepatic fatty change is a common lesion. Two forms are recognized: micro- and macrovesicular steatosis, the former being much less frequent and more serious than the latter. The case of an alcoholic woman under anticonvulsivant therapy and with medications for a syndrome of inappropriate secretion of antidiuretic hormone (SIADH) who presented with rapidly progressive cholestasis and hepatocellular failure is reported. Massive macro- and micro-vesicular hepatic steatosis was diagnosed at autopsy. The authors review the clinico-pathological features associated with this condition, and causal factors possibly implicated in this case are discussed in regard with currently considered pathophysiological mechanisms. [less ▲]

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See detailEvidence For The Assignment Of Two Strains Of Splv To The Genus Potyvirus Based On Coat Protein And 3' Non-Coding Region Sequence Data
Colinet, Dominique; Kummert, Jean; Lepoivre, Philippe ULg

in Virus Research (1997), 49(1), 91-100

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See detailcompte rendu de : Les Grecs et l'Occident. Actes du colloque de la Villa "Kérylos" (1991), Rome, 1995
Rochette, Bruno ULg

in Revue Belge de Philologie et d'Histoire (1997), 75(1), 156-158

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See detailPromoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations.
Kas, K.; Voz, Marianne ULg; Roijer, E. et al

in Nature Genetics (1997), 15(2), 170-4

Pleiomorphic adenoma of the salivary glands is a benign epithelial tumour occurring primarily in the major and minor salivary glands. It is by far the most common type of salivary gland tumour ... [more ▼]

Pleiomorphic adenoma of the salivary glands is a benign epithelial tumour occurring primarily in the major and minor salivary glands. It is by far the most common type of salivary gland tumour. Microscopically, pleiomorphic adenomas show a marked histological diversity with epithelial, myoepithelial and mesenchymal components in a variety of patterns. In addition to a cytogenetic subgroup with normal karyotypes, pleiomorphic adenomas are characterized by recurrent chromosome rearrangements, particularly reciprocal translocations, with breakpoints at 8q12, 3p21, and 12q13-15, in that order of frequency. The most common abnormality is a reciprocal t(3;8)(p21;q12). We here demonstrate that the t(3;8)(p21;q12) results in promoter swapping between PLAG1, a novel, developmentally regulated zinc finger gene at 8q12, and the constitutively expressed gene for beta-catenin (CTNNB1), a protein interface functioning in the WG/WNT signalling pathway and specification of cell fate during embryogenesis. Fusions occur in the 5'-non-coding regions of both genes, exchanging regulatory control elements while preserving the coding sequences. Due to the t(3;8)(p21;q12), PLAG1 is activated and expression levels of CTNNB1 are reduced. Activation of PLAG1 was also observed in an adenoma with a variant translocation t(8;15)(q12;q14). Our results indicate that PLAG1 activation due to promoter swapping is a crucial event in salivary gland tumourigenesis. [less ▲]

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See detailA la mémoire de Daniel P. Bobon, Mafhoud Boucebci, Amadeo Sanchez Blanque, Jean Mirel
Mormont, Christian ULg

in Acta Psychiatrica Belgica (1997), 97(Suppl. 1), 2-7

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See detailFusion Of Bovine Leukemia Virus With Target Cells Monitored By R18 Fluorescence And Pcr Assays
Zarkik, S.; Defrisequertain, F.; Portetelle, Daniel ULg et al

in Journal of Virology (1997), 71(1),

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See detailMusaespora kalbii (lichenized Ascomycetes: Melanommatales), a new foliicolous lichen with a pantropical distribution
Lücking, Robert; Sérusiaux, Emmanuël ULg

in Nordic Journal of Botany (1997), 16

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See detailModulation of lung inflammation in the control of bovine respiratory disease
Van de Weerdt, ML; Lekeux, Pierre ULg

in Bovine Practitioner (1997), 31.1

The purpose of this paper is to review the potential strategies which could improve the treatment of respiratory disorders in general and the modulation of lung inflammation in particular. Possible ... [more ▼]

The purpose of this paper is to review the potential strategies which could improve the treatment of respiratory disorders in general and the modulation of lung inflammation in particular. Possible preventive treatments will not be discussed in this review. [less ▲]

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See detailHair follicle involvement in herpes zoster
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Virchows Archiv : An International Journal of Pathology (1997), 430

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See detailAbdominal sequelae after pedicled TRAM flap breast reconstruction
PETIT, JY; RIETJENS, M; FERREIRA, M et al

in Plastic and Reconstructive Surgery (1997), 99

A considerable interest in autologous tissue breast reconstructions has developed recently, especially since Food and Drug Administration (FDA) experts have raised the polemic on silicone implants ... [more ▼]

A considerable interest in autologous tissue breast reconstructions has developed recently, especially since Food and Drug Administration (FDA) experts have raised the polemic on silicone implants. Although such enthusiasm for the transverse rectus abdominis musculocutaneous (TRAM) flap is justified in what concerns the final cosmetic result of the reconstructed breast, the risk of abdominal sequelae should be explained to the patient. Abdominal scarring, parietal weakness, strength loss, and back pain have been recorded in a series of pedicled TRAM flap reconstructions performed at the Institut Gustave-Roussy before 1991. Cosmetic results of the abdomen were tested by three independent judges on the photographs taken of 132 patients. The global appearance of the abdomen was rated as "natural" in 70 percent of the patients. The umbilical scar was unacceptable in 25 percent and very good or not visible in 21 percent. The lower abdominal scar was rated as "not acceptable" in 35 percent. Abdominal strength was tested among the 38 patients who underwent both preoperative and postoperative muscular testing, of whom 18 had single-pedicled and 20 had bipedicled TRAM flap reconstructions. In the first group, the physiotherapist observed an impairment of function of the upper portion of the rectus abdominis and of the oblique muscle in almost 50 percent. In the second group, the same muscles were more severely impaired (in 60 percent), as well as the function of the lower portion of the rectus (in 15 percent). The percentage of patients complaining of "light back pain" in the 6-month postoperative period was 55 percent in the single-pedicle group and 30 percent in the double-pedicle group. However, 20 percent of the bipedicled patients complained of "severe" back pain, while there was none in the single-pedicled group. In conclusion, abdominal sequelae after TRAM flap breast reconstruction should not be underestimated and constitute one of the drawbacks of the technique when it is compared with reconstruction with a prosthesis. [less ▲]

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See detailCertification in the meat channel.
Mortiaux, Frédéric; Renaville, Robert ULg; Gengler, Nicolas ULg et al

in Journal of Animal Science (1997), 75(1), 136

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See detailNanoindentation and scanning force microscopy as a novel method for the characterization of tribological transfer films
Randall, N. X.; Bozet, Jean-Luc ULg

in Wear (1997), 212(1), 18-24

In conventional pin-on-disk testing of the tribological characteristics of two different materials in sliding contact, the main parameters of interest are notably the friction and wear properties of the ... [more ▼]

In conventional pin-on-disk testing of the tribological characteristics of two different materials in sliding contact, the main parameters of interest are notably the friction and wear properties of the material pair. However, when two bodies consisting of hard and soft materials respectively are subjected to such testing, the appearance of a transfer film, or third body, which can be a composite mixture of the two, is often observed. Until now the characterization of transfer films in terms of their mechanical properties has been hampered by their nonhomogeneous distribution across a tested surface, their small size, low thickness and the difficulty in accurately positioning a test probe such that the film properties can be measured independently from those of the substrate. In this paper a new method is introduced, consisting of nanoindentation and scanning force microscopy (SFM), which is capable of highly localized indentation testing of a specified sample site with high resolution imaging of the area prior to and after indentation. In this way the hardness and modulus of a transfer film can be obtained, as well as valuable surface topographical information concerning the material response to the indentation. Measurements are presented for the material pair A286/polyimide after testing on a pin-on-disk tribometer in ambient air and liquid nitrogen. Distinct variations in hardness between the transfer films and their contacting bodies have een observed and correlated to the wear behaviour and testing environment. (C) 1997 Elsevier Science S.A. [less ▲]

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See detailHerpesvirus Of Turkeys Homologue Of Hsv Vp16 Is Structurally Related To Varicella Zoster Virus Trans-Inducing Protein Encoded By Orf 10
Kopacek, J.; Zelnik, V.; Brasseur, Robert ULg et al

in Virus Genes (1997), 15(1), 45-52

Expression of the immediate-early genes of alpha-herpesviruses is stimulated by a family of trans-inducing factors represented by VP16 of HSV-1 and ORF10 gene product of VZV. We have identified and ... [more ▼]

Expression of the immediate-early genes of alpha-herpesviruses is stimulated by a family of trans-inducing factors represented by VP16 of HSV-1 and ORF10 gene product of VZV. We have identified and determined the nucleotide sequence of the UL48 gene encoding the herpesvirus of turkeys (HVT) homologue of HSV VP16. The gene maps to the BamHI-J fragment and appears to be expressed in a form of bicistronic transcript together with UL49. The deduced amino acid sequence of the protein encoded by HVT UL48 gene shows 55% identity with MDV UL48 gene product. Like the majority of related proteins in other alpha-herpesviruses, the protein encoded by HVT UL48 gene lacks the acidic C-terminal tail, known to possess the transactivation capacity of HSV VP16. Hydrophobic cluster analysis has revealed that its predicted domain composition is closely related to the transactivator protein encoded by ORF10 of VZV. However, the putative amino-terminal activation domain of the HVT homologue of HSV VP16 does not contain a typical horseshoe-like hydrophobic cluster found in other alpha-herpesvirus homologues, suggesting either that it acts as a transactivator via a different activation domain or that its transactivation potential is diminished. [less ▲]

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See detailEtude comparative de la décontamination microbiologique, avec ou sans Biosol, de terres d'excavation contaminées par des hydrocarbures
Verstaete, W.; Van Eyck, L.; Thonart, Philippe ULg et al

in Tribune de l'Eau (La) (1997), 587/3

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See detailSoluble and cell-associated transferrin receptor in lung cancer.
Dowlati, A.; Loo; Bury, Thierry ULg et al

in British Journal of Cancer (1997), 75(12), 1802-6

The expression of transferrin receptor (TfR) has been identified in many malignant tumours. In lung cancer, lymphoma and breast cancer, it has been shown that the expression of TfR correlates with tumour ... [more ▼]

The expression of transferrin receptor (TfR) has been identified in many malignant tumours. In lung cancer, lymphoma and breast cancer, it has been shown that the expression of TfR correlates with tumour differentiation, probably implying some prognostic value. A soluble form of TfR (sTfR) in human serum has been shown to be proportional to the number of cellular TfRs. Based on these data we examined the utility of measuring sTfR in the serum and bronchoalveolar lavage (BAL) fluid of patients with lung cancer (n = 32) and patients with chronic obstructive pulmonary disease (n = 22). BAL fluid was centrifuged to separate the supernatant from the cellular component. Cells were lysed in a detergent and cell-associated TfR was measured by enzyme-linked immunosorbent assay (ELISA) and expressed as ng 10(-6) cells in this cellular component. There was no difference in serum sTfR between the cancer and chronic obstructive pulmonary disease (COPD) groups. A higher level of cell-associated TfR was found in BAL of non-small-cell lung cancer patients than in COPD patients (P = 0.01). The calculated number of TfR molecules per cell in BAL correlated positively with the percentage of macrophages in BAL (P < 0.0001), suggesting that cell-associated TfR in BAL originates primarily from macrophages in this fluid. No correlation existed between BAL cell-associated TfR and tumour size, nodal status, the presence of metastases and serum sTfR. BAL cell-associated TfR was negatively correlated with BAL supernatant neuron-specific enolase (NSE) (P = 0.01). A combination of BAL supernatant NSE and cell-associated TfR detected lung cancer with a sensitivity of 91%, a specificity of 59% and positive and negative predictive values of 81% and 71% respectively. In conclusion, BAL cell-associated TfR may help in the differential diagnosis of lung cancer vs pneumonia. [less ▲]

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See detailBovine Herpesvirus 1-Induced Apoptosis Occurs At The G0/G1 Phase Of The Cell Cycle
Hanon, Emilien ULg; Hoornaert, S.; Dequiedt, Franck ULg et al

in Virology (1997), 232(2), 351-358

We have previously shown that bovine herpesvirus 1 (BHV-1), even when inactivated, induces apoptotic cell death in mitogen-stimulated bovine peripheral blood mononuclear cells (PBMCs) (Hanon et al., 1996 ... [more ▼]

We have previously shown that bovine herpesvirus 1 (BHV-1), even when inactivated, induces apoptotic cell death in mitogen-stimulated bovine peripheral blood mononuclear cells (PBMCs) (Hanon et al., 1996, J. Virol. 70, 4116-4120). In order to gain insight into this process, we have investigated the cell cycle phase at which BHV-1 induces apoptosis in PBMCs. Our results show that the percentage of cells that progress through the S phase was always lower in BHV-1-infected PBMCs than in control cells. This effect was not due to a defective activation of mitogen-stimulated PBMCs since BHV-1 only slightly affected the percentage of cells expressing BoCD25, a well-known lymphocyte activation marker. Furthermore, mimosine and cyclosporine A, two chemicals that inhibit entry into the S phase of the cell cycle by different pathways, did not affect the ability of BHV-1 to induce apoptosis. BHV-1-induced apoptosis also occurred in unstimulated PBMCs and interestingly, this was associated with the expression of c-myc and BoCD25 proteins both of which are related to cell cycle progression. All together, these data provide evidence demonstrating that BHV-1-induced apoptosis occurs at the G0/G1 phase of the cell cycle. [less ▲]

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See detailField observations of the spawning behaviour of European grayling
Darchambeau, François ULg; Poncin, Pascal ULg

in Journal of Fish Biology (1997), 51(5), 1066-1068

During observations of the River Ourthe, Belgium, 70 spawning attempts were recorded during the reproductive period of the European grayling. Thirty-six per sent of the spawning attempts proceeded to ... [more ▼]

During observations of the River Ourthe, Belgium, 70 spawning attempts were recorded during the reproductive period of the European grayling. Thirty-six per sent of the spawning attempts proceeded to completion, while interference by another male may explain some of the incomplete acts. Sneaking behaviour was observed and one spawning act included two males and one female. (C) 1997 The Fisheries Society of the British Isles. [less ▲]

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See detailCharacterization of Clostridium perfringens isolates from goats.
Phukan, A.; Dutta, G.-N.; Daube, Georges ULg et al

in Indian Veterinary Journal (The) (1997), 74

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See detailLa cartographie des hydrophytes appliquée à l'étude des écosystèmes fluviaux: un outil d'analyse pour la restauration des anciens chenaux rhénans
Klein, J. P.; Vanderpoorten, Alain ULg; Sanchez-Perez, J. et al

in Lejeunia, Revue de Botanique (1997), 153

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See detailSynthesis and biological evaluation of sulfonylcyanoguanidines and sulfonamidonitroethylenes as bioisosteres of hypoglycemic sulfonylureas
Masereel, B.; Ouedraogo, R.; Dogne, J.-M. et al

in European Journal of Medicinal Chemistry (1997), 32

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See detailContribution à l'étude de la flore et de l'écologie des plantes de quelques grottes wallonnes.
Garbacki, Nancy ULg

in Bulletin des Chercheurs de la Wallonie (1997), XXXVI

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See detailInfluence of whole milk in diet of growing fattening Belgian Blue bulls on animal performances and on fatty acid composition in subcutaneous, intermuscular and intramuscular fats
Hornick, Jean-Luc ULg; Clinquart, Antoine ULg; Van Eenaeme, Christian ULg et al

in Livestock Production Science (1997), 48

Influence of milk in diet of growing fattening Belgian Blue bulls on animal performances and on fatty acid composition in subcutaneous, intermuscular and intramuscular fats. The use of milk as component ... [more ▼]

Influence of milk in diet of growing fattening Belgian Blue bulls on animal performances and on fatty acid composition in subcutaneous, intermuscular and intramuscular fats. The use of milk as component of a fattening diet for bulls was studied in an experiment carried-out over 2 years with Belgian Blue bulls. The animals weighed 305 kg at the beginning of the experiment. In all, 15 bulls were given a control concentrate fattening diet (control group, CG), while 11 others were fed concentrate plus 6.5 to 11 1 whole milk per day according to weight or age (milk group, MG). The fattening period lasted for 174 and 181 d respectively in groups CG and MG. The MG-group had a higher killing-out percentage (P < 0.01) and the meat was characterized by a lower b* value and a lower dry matter content (P < 0.1). Whole milk in the diet increased the proportion of shorter chain and saturated fatty acids in fat (P < 0.001) and reduced the proportion of mono- and polyunsaturated acids (P < 0.05; P < 0.1). The extent of the changes were larger in subcutaneous and intermuscular fats than in intramuscular fat. [less ▲]

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See detailVaux-et-Borset : campagne de fouilles 1995
Caspar, Jean-Paul; Delye, Emmanuel ULg; Bit, Richard et al

in Chronique de l'Archéologie Wallonne (1997), 4-5

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See detailAerogel compression theoretical analysis
Pirard, René ULg; Pirard, Jean-Paul ULg

in Journal of Non-Crystalline Solids (1997), 212(2-3), 262-267

Several authors have empirically shown that, in aerogels, a power law exists between the mechanical moduli and the bulk density. An exponent value can be determined from mercury porosimetry curves. The ... [more ▼]

Several authors have empirically shown that, in aerogels, a power law exists between the mechanical moduli and the bulk density. An exponent value can be determined from mercury porosimetry curves. The shrinkage of aerogels under mercury pressure follows a buckling mechanism which links the pore size to the exerted pressure. The present study relates the exponent to the pore volume distribution which can be described by a hierarchical model valid in a large range of pore size, so a physical meaning is given to the exponent. [less ▲]

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See detailLa torsion isolée de la rate : cas clinique et revue de la littérature
Zonderland, J. L.; Balligand, Marc ULg; Snaps, Frédéric ULg et al

in Annales de Médecine Vétérinaire (1997), 141

This paper describes a case report and reviews the literature concerning isolated torsion of the splenic pedicle in a dog. Splenic torsion is found in young, large and deep-chested dogs with a prevalence ... [more ▼]

This paper describes a case report and reviews the literature concerning isolated torsion of the splenic pedicle in a dog. Splenic torsion is found in young, large and deep-chested dogs with a prevalence of 3.5 to 6%. The pathogenesis of isolated splenic torsion is unknown, Clinical signs and diagnostic procedures are non specific. Only sonographic changes are valuable in performing an etiologic diagnosis, The surgical treatment consists in a splenectomy, An early diagnosis and surgical treatment usually lead to a good prognosis. [less ▲]

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See detailPerspective in the treatment of insulin resistance.
Scheen, André ULg

in Human Reproduction (1997), 12 Suppl 1

Improving the action of insulin is a relatively new concept in therapy. It should, however, become more and more important because of the rapid expansion of the insulin resistance syndrome (including ... [more ▼]

Improving the action of insulin is a relatively new concept in therapy. It should, however, become more and more important because of the rapid expansion of the insulin resistance syndrome (including upper body adiposity, glucose intolerance, hypertension, dyslipidaemia, etc.) in industrialized countries and its dramatic consequences for public health. Insulin sensitivity can be improved by non-pharmacological means, essentially reduction of excessive body weight, promotion of regular physical activity and modification of dietary habits, as well as, possibly, cessation of smoking and correction of subclinical magnesium deficiency. Currently available pharmacological means mainly include the biguanide compound metformin and possibly anti-obesity agents, such as (d-) fenfluramine, fluoxetine and benfluorex. New compounds aiming at improving the action of insulin are in development, especially the thiazolidinedione derivatives (e.g. troglitazone), known as 'insulin sensitizers'. Treatment of insulin resistance may have important gynaecological applications, essentially in polycystic ovary syndrome and, possibly, after menopause. Hopefully, improving insulin sensitivity could ameliorate the cardiovascular prognosis of numerous individuals having some or all components of insulin resistance syndrome. [less ▲]

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See detailStudies on the O-J-I-P transient of chlorophyll fluorescence in relation to photosystem II assembly and heterogeneity in plastids of greening barley
Barthelemy, X.; Popovic, R.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (1997), 39(3), 213-218

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of ... [more ▼]

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of etiolated leaves of Hordeum vulgare. The initial photochemical phase (O-J) due to reduction of the primary quinone acceptor Q(A) was found to represent a constant proportion (65-70%) of total variable fluorescence independent of greening time. The partial fluorescence quenching in the Q(A)-reduced state seems, therefore, to represent a basic property of PSII electron transport. The biphasic character of the slower J-I-P transient due to reduction of the plastoquinone pool developed progressively during the first hours of greening. in the same period of lime the proportion and rate constant of rapid PSII alpha sub-population increased, as calculated from the induction curve in the presence of DCMU. Etiochloroplasts or chloroplasts resuspended in low salt medium showed a low I level, which was restored upon readdition of 5 mM MgCl2 and NaCl. Salts also increased the apparent proportion of PSII alpha. These results suggest that the J-I and I-P phases of the induction curve are related to different rates of plastoquinone photoreduction by two distinct PSII populations. The effects of DMQ and of DCBQ on the O-J-I-P transient were also studied in (etio-)chloroplasts, In addition to the already reported quenching of the initial (F-0) and variable fluorescence by DCBQ, a slow fluorescence increase phase was found to appear upon the addition of DCBQ but not of DMQ. The latter observations confirm that DCBQ differs from DMQ by its higher efficiency as PSII electron acceptor. (C) 1997 Elsevier Science S.A. [less ▲]

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See detailVers une chirurgie mammaire supraconservatrice des lésions mammaires infracliniques?
LIFRANGE, Eric ULg; COLIN, Claude

in Gunaïkeia (1997), 2

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See detailRelationships of growth hormone gene and milk protein polymorphisms to milk production traits in Simmental cattle
Falaki, M.; Prandi, A.; Corradini, C. et al

in Journal of Dairy Research (1997), 64(1), 47-56

The importance of milk proteins and the positive effect of administration of growth hormone (GH) on milk production, and the presence in some dairy cattle lines of greater GH concentrations prompted us to ... [more ▼]

The importance of milk proteins and the positive effect of administration of growth hormone (GH) on milk production, and the presence in some dairy cattle lines of greater GH concentrations prompted us to examine the presence of restriction fragment length polymorphism at the GH gene using the restriction enzyme TaqI and to investigate associations between this polymorphism in Simmental cows and bulls, as well as milk protein variants in Simmental cows, and milk production traits. Blood and milk were sampled from 279 Italian Simmental cows and semen was collected from 148 bulls of the same breed. Two fragment bands, denoted A and B, of 6200 and 5200 bp respectively, were examined and three patterns, AA, AB and BB, were found in both animal samples. All variants previously reported in other studies, for kappa, beta, and alpha(s1)-caseins, and beta-lactoglobulin, were found in the cows' samples. For the cows' samples, a BLUP (Best Linear Unbiased Predictor) analysis of results was performed using a REML (Restricted Maximum Likelihood) program and known heritabilities, whereas for bulls we have performed a General Linear Model analysis. The effect of GH gene polymorphism, using TaqI restriction enzyme, on milk production traits was not significant, but bulls of BB pattern had a higher breeding value for milk yield than AA bulls (P < 0.05). For the kappa-casein genotypic effects, cows of AB genotype gave milli with 1.53+/-0.70 g/kg less fat than cows of AA genotype. In addition, breeding values for milk protein content were significantly higher in BB bulls, with 0.87+/-0.32 and 0.71+/-0.34 g/kg more milk protein than AA and AB bulls respectively. Thus, our results revealed a GH gene polymorphism and indicated significant effects of milk protein polymorphisms on milk production traits in the Italian Simmental breed. [less ▲]

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See detailChimie et immunologie: controle de qualite des eaux.
Portetelle, Daniel ULg; Copin, A.; Hecquet, J. F.

in Agricontact (1997), (290),

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See detailOncogenic potential of Tax requires phosphorylation on serines 106 et 293.
Willems, Luc ULg; Grimonpont, Catherine; Kerkhofs, Pierre et al

in Virus Research (1997), 47(2 -Special Issue), 121-122

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See detailRésumé des communications et livret guide des excursions
Petit, François ULg; Wastiaux, Cécile; Assani, Ali Arkamose et al

in Journées hydrologiques françaises (Commission des Hydrosystèmes fluviaux) Journées de terrain organisées en Ardenne et dans les Hautes fagnes (1997)

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See detailIA-2-autoantibodies complement GAD65-autoantibodies in new-onset IDDM patients and help predict impending diabetes in their siblings. The Belgian Diabetes Registry.
Gorus, F. K.; Goubert, P.; Semakula, C. et al

in Diabetologia (1997), 40(1), 95-9

IA-2 has been identified as an autoantigen that is recognized by immunoglobulins from insulin-dependent diabetic (IDDM) patients. Using a liquid phase radiobinding assay, we performed an IA-2-autoantibody ... [more ▼]

IA-2 has been identified as an autoantigen that is recognized by immunoglobulins from insulin-dependent diabetic (IDDM) patients. Using a liquid phase radiobinding assay, we performed an IA-2-autoantibody (IA-2-Ab) assay in 474 IDDM patients and 482 non-diabetic control subjects aged 0-3 years. IA-2-Ab were detected in 58% of the patients and 0.8% of control subjects. Their prevalence in patients was lower than that of islet cell autoantibodies (ICA; 73%) or glutamic acid decarboxylase (M(r) 65 kDa)-autoantibodies (GAD65-Ab; 82%) but higher than that of insulin autoantibodies (IAA; 42%). IA-2-Ab were more frequent in patients under age 20 years (70%) than between 20 and 40 years (45%; p < 0.001). In the whole IDDM group, 92% of patients were positive for at least one of the three molecular assays, which is higher than the positivity for the ICA assay (73%). Only 1% was negative in the molecular assays and positive in the ICA assay. IA-2-Ab levels were positively correlated with ICA titres (p < 0.001) and HLA DQ A1*0301-DQ B1*0.02 (p < 0.003) by multivariate analysis. In a group of 481 non-diabetic siblings (age 0-39 years) of IDDM patients only 7 were IA-2-Ab positive (1.5%). All seven were under age 20 years and positive for at least two other autoantibodies and for DQ A1*0301-DQB1*0302. Four of these seven developed IDDM during the 6-70-month follow-up period. The positive predictive value of IA-2-Ab (57%) was higher than that of ICA, GAD65-Ab or IAA alone, or in combination (< or = 20%) but these calculations are restricted by the relatively short observation period and the small number of cases. The only IA-2-Ab-negative case of pre-diabetes was also negative for IAA and GAD65-Ab, while it was strongly positive for ICA. In conclusion, IA-2-Ab show a high diagnostic specificity for IDDM and are predictive markers of impending diabetes in siblings of patients. In combination with other molecular antibody assays they may replace ICA testing in future. Our data also indicate that other autoantibodies than IA-2-Ab, GAD65-Ab and IAA contribute to ICA. [less ▲]

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See detailEtudes phénoménologiques
Ryle, Gilbert; Leclercq, Bruno ULg

in Recherches Husserliennes (1997), 7

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See detailLoss of type IV collagen alpha 5 and alpha 6 chains in human invasive prostate carcinomas
Dehan, Pierre ULg; Waltregny, David ULg; Beschin, Alain et al

in American Journal of Pathology (1997), 151(4), 1097-104

Type IV collagen, a major component of basement membranes, is organized in a network responsible for the mechanical resistance of the basement membranes. It also plays a key role in epithelial cell ... [more ▼]

Type IV collagen, a major component of basement membranes, is organized in a network responsible for the mechanical resistance of the basement membranes. It also plays a key role in epithelial cell adhesion to basement membranes. This study was designed to investigate the distribution of type IV collagen alpha-chains in normal, preneoplastic, and malignant prostate basement membranes. For this purpose, immunohistochemistry using specific antibodies raised against the different alpha-chains of type IV collagen was performed in eight normal samples, six prostatic intraepithelial neoplasia, and 20 malignant lesions of the prostate. Our results demonstrate the presence of the "novel" alpha 5 (IV) and alpha 6 (IV) chains along with the "classical" alpha 1 (IV)/alpha 2 (IV) chains in the basement membrane of the normal prostate gland. The alpha 3 (IV) chain was never detected in any prostate specimen. Prostatic intraepithelial neoplasia showed a similar immunostaining pattern to that found in normal glands. In cancer gland basement membranes, we demonstrate for the first time a specific loss of the alpha 5 (IV) and alpha 6 (IV) chains, whereas the classical alpha 1 (IV) and alpha 2 (IV) chains were consistently exhibited. Additionally, type VII collagen colocalized with alpha 5 (IV) collagen chain, and these two proteins, which were always observed in normal and prostatic intraepithelial neoplasia gland basement membranes, were lost in invasive carcinoma basement membranes. This observation raises questions about the possible association or cooperation between alpha 5 (IV)/alpha 6 (IV) chains and anchoring fibrils in prostate glands basement membrane. [less ▲]

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See detailLa contestation des pierres. Des œuvres écrites d'Olivier Smolders
Badir, Sémir ULg

in Textyles : Revue des Lettres Belges de Langue Française (1997), 14

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See detailDopamine 'D2-like' receptor agonists in combination with cocaine: absence of interactive effects on locomotor activity.
Tirelli, Ezio ULg; Reggers, Jean ULg; Terry, P.

in Behavioural Pharmacology (1997), 8(2-3), 147-59

This study examined interactions between cocaine and drugs that act as direct agonists at subtypes of "D2-like" dopamine receptors. The drugs 7-OH-DPAT, quinpirole and RU24213 were studied alone and in ... [more ▼]

This study examined interactions between cocaine and drugs that act as direct agonists at subtypes of "D2-like" dopamine receptors. The drugs 7-OH-DPAT, quinpirole and RU24213 were studied alone and in combination with cocaine for their effects on locomotor activity in non-habituated mice. Locomotor activity was measured by photobeam crossings over 140 min. At the doses given (7-OH-DPAT: 0.006-6.4 mg/kg; quinpirole: 0.001-1 mg/kg; RU24213: 0.008-8 mg/kg) all three direct agonists dose-dependently reduced locomotor activity throughout the test, whereas cocaine (0.6-20 mg/kg) produced dose-related hyperactivity. Next, for each direct agonist, a series of doses was selected (up to threshold behaviourally-active doses) as pretreatments to a sub-maximally stimulant dose of cocaine (15 mg/kg). 7-OH-DPAT and quinpirole did not modulate the effects of cocaine; RU24213 produced, at best, a very modest attenuation of the effects of cocaine. Finally, a series of cocaine doses (below stimulant threshold) was given before a single dose of each direct agonist (the lowest dose to reduce activity significantly). Cocaine did not reliably alter the hypoactivity produced by any of the D2-like agonists. By demonstrating negligible interactions between cocaine and D2-like agonists, the results fail to demonstrate any necessary involvement of D2-like receptors in one of the behavioural effects of cocaine. [less ▲]

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See detailAge model estimation in paleoclimatic research : fuzzy regression and radiocarbon uncertainties
Boreux, Jean-Jacques ULg; Pesti, G.; Duckstein, L. et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (1997), 128(1), 29-37

A fuzzy linear regression-based method to relate the depth and age of sediment layers is described. Because algae, moss or local plants respond to climatic change, the age and depth of sediment layers are ... [more ▼]

A fuzzy linear regression-based method to relate the depth and age of sediment layers is described. Because algae, moss or local plants respond to climatic change, the age and depth of sediment layers are interrelated variables but the link between them is often imprecise. In most cases, due to the limited number of layers in a core (i.e., small number of data points), estimation of the slope and uncertainties in classical regression analysis does not take into account the uncertainties in radiocarbon dating. Here, fuzzy linear regression, which may be applied even to a very small data set, is utilized. The method, illustrated through a practical example, with eight data points, appears to be a promising tool in stratigraphic studies to link sediment age to layer depth and takes into account uncertainties from radiocarbon dating. [less ▲]

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See detailComment les enseignants évaluent-ils la géométrie au premier degré de l'enseignement secondaire ?
Burton, Réginald; Detheux-Jehin, Monique; Fagnant, Annick ULg

in Informations pédagogiques (1997), 38(15), 24

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See detailESRA guidelines for the use of epidural opioids
Aguilar, J. L.; Benhamou, D.; Bonnet, F. et al

in International Monitor on Regional Anaesthesia (1997), 9

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See detailEffects of level of intake and of available volatile fatty acids on the absorptive capacity of sheep rumen
Doreau, Michel; Ferchal, Edwin; Beckers, Yves ULg

in Small Ruminant Research (1997), 25

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See detailUn cas de néoténie dans un bâtiment désaffecté, chez le Triton alpestre, Triturus alpestris apuanus (Salamandridae)
Denoël, Mathieu ULg

in Alytes (1997), 15

A population of Triturus alpestris apuanus of the Apuane Alps (Tuscany , Italy) was studied during July 1994. The particularity of this population is that it breeds in an artificial site, in the dark and ... [more ▼]

A population of Triturus alpestris apuanus of the Apuane Alps (Tuscany , Italy) was studied during July 1994. The particularity of this population is that it breeds in an artificial site, in the dark and under cover, in a deserted building. Moreover some neotenic newts were discovered. The recent colonization and the instability of this biotope indicate a form of labile neoteny, appearing and disappearing spontaneously. [less ▲]

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See detailEffect of activators and inhibitors of K+-channels on insulin secretion in the amphibian pancreas
Francini, F.; Pirotte, Bernard ULg; Gagliardino, J. J.

in Archives of Physiology & Biochemistry (1997), 105

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See detailA global model of the biosphere : validation and applications to present and past climatic conditions
François, Louis ULg; Gérard, Jean-Claude ULg; Nemry, Bernard et al

in Sciences Géologiques. Bulletin (1997), 50(1-4), 89-107

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See detail125I-Tyr0-hCRH labelling characteristics of corticotropin-releasing hormone receptors: differences between normal and adenomatous corticotrophs.
Abs, R.; Smets, G.; Vauquelin, G. et al

in Neurochemistry International (1997), 30(3), 291-297

The presence of corticotropin-releasing hormone (CRH) receptors has been previously demonstrated in corticotrophs from normal pituitaries using a method combining immunocytochemistry and liquid emulsion ... [more ▼]

The presence of corticotropin-releasing hormone (CRH) receptors has been previously demonstrated in corticotrophs from normal pituitaries using a method combining immunocytochemistry and liquid emulsion autoradiography. The aim of this study was to compare the characteristics of the 125I-Tyr0-hCRH binding in corticotrophs from normal pituitaries (three obtained at autopsy and one obtained at surgery) with corticotrophs from pituitary adenomas (six corticotroph adenomas responsible for Cushing's disease and two silent corticotroph adenomas secreting a biologically inactive ACTH molecule). In normal corticotrophs, the larger part of the 125I-Tyr0-hCRH binding was localised in patchy conglomerates at the centre of the cell and, to a much lesser degree, in a diffuse pattern at the cell periphery. In adenomatous corticotrophs, CRH receptor expression is disturbed both quantitatively and qualitatively. Except for a minority of cells in one adenoma, all adenomatous corticotrophs showed only peripherally bound 125I-Tyr0-hCRH and no centrally localised binding. Furthermore, adenomatous corticotrophs revealed a statistically significant lower signal intensity when compared to normal corticotrophs and a strongly negative correlation was found between the labelling area in adenomatous corticotrophs and both the basal and CRH-stimulated plasma ACTH levels. These findings suggest defective processing of CRH receptors and could be relevant to the sustained ACTH secretion by adenomatous corticotrophs in Cushing's disease and, more generally, provide an explanation to its pathology. The silent corticotrophs secreting a biologically inactive ACTH molecule were characterised by a very faint signal intensity, although present on almost every cell. [less ▲]

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See detailComment j'explore ... le syndrome d'insulinoresistance grace a ses marqueurs biologiques.
Luyckx, Françoise ULg; Scheen, André ULg; Gielen, Jean-Louis ULg et al

in Revue Médicale de Liège (1997), 52(10), 686-91

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See detailDesign Of A New Class Of Amphipathic Helical Peptides For The Plasma Apolipoproteins That Promote Cellular Cholesterol Efflux But Do Not Activate Lcat
Labeur, C.; Lins, Laurence ULg; Vanloo, B. et al

in Arteriosclerosis, Thrombosis, and Vascular Biology (1997), 17(3), 580-8

Amphipathic helical peptides represent the lipid-binding units of the soluble plasma apolipoproteins. Several synthetic peptide analogues have been designed to mimic such structures and have been used to ... [more ▼]

Amphipathic helical peptides represent the lipid-binding units of the soluble plasma apolipoproteins. Several synthetic peptide analogues have been designed to mimic such structures and have been used to unravel some of the mechanisms involved in the physiological function of the apolipoproteins, including lipid binding, LCAT activation, and enhancement of cholesterol efflux from lipid-laden cells. A series of novel synthetic peptides, named ID peptides, was modeled on the basis of the structural properties common to the amphipathic helices of apolipoprotein (apo) A-I. In these new peptides, however, the segregation between hydrophobic and hydrophilic faces of the helices is more pronounced than in apoA-I, so that the surface of the hydrophobic and hydrophilic faces of the amphipathic helices is equal. Moreover, there are fewer negatively charged residues in the center of the hydrophilic face of the helical peptides. Most charged amino acids are located along the edge of the helix and are susceptible to forming salt bridges with residues of an antiparallel helix, such as around a discoidal phospholipid/peptide complex. The physicochemical characteristics of these peptides and their complexes with phospholipids were compared with those of the 18A peptide and its lipid/peptide complex. All ID peptides bind dimyristoylphosphatidylcholine vesicles more rapidly than the 18A peptide to yield discoidal peptide/phospholipid complexes of comparable size. The alpha-helical content of the lipid-free ID peptides is close to that of the 18A peptide and increases slightly on lipid binding. The stability of the ID and 18A peptides and of the phospholipid/peptide complexes against guanidinium hydrochloride denaturation is higher than that of lipid-free and lipid-bound apoA-I. LCAT activation by the 18A/phospholipid/cholesterol complexes equals that of apoA-I/ phospholipid/cholesterol complexes, whereas none of the ID peptides tested is able to activate LCAT to a significant extent. Incubation of the peptide/phospholipid complexes with lipid-laden macrophages induces cellular cholesterol efflux and incorporation of cholesterol into the complexes. The cholesterol efflux capacity of the peptide/phospholipid complexes is comparable among the peptides and higher than that of apoprotein/phospholipid complexes. In conclusion, although the amphipathicity of the new peptides is higher than that of the 18A model peptide, the lack of LCAT activation by the ID peptides suggests that an enhanced segregation of the hydrophobic and hydrophilic residues, equal magnitude of hydrophobic and hydrophilic faces of the helix, and the absence of negatively charged residues in the central part of the hydrophilic face might account for the lack of LCAT activity of these peptides. These parameters do not affect the capacity of the peptide/phospholipid complexes to promote cellular cholesterol efflux. [less ▲]

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See detailMeasurements of the ground state ionization energy and wavelengths for the 1snp1P1 - 1s2 1S0(n=4-10) lines of O VII
Bartnik, A.; Biémont, Emile ULg; Dyakin, V. M. et al

in Journal of Physics : B Atomic Molecular & Optical Physics (1997), 30

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See detailLe sondage de Focant: lithostratigraphie et implications structurales
Boulvain, Frédéric ULg; Coen-Aubert, M.

in Memoirs of the Geological Survey of Belgium (1997), 43

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See detailAssociative chunk strength in artificial grammar learning
Meulemans, Thierry ULg; Van der Linden, Martial ULg

in Journal of Experimental Psychology. Learning, Memory & Cognition (1997), 23(4), 1007-1028

In four experiments, adherence to grammatical rules and associative chunk strength (including different measures, each calculated on the basis of the frequency with which bigrams and trigrams present in ... [more ▼]

In four experiments, adherence to grammatical rules and associative chunk strength (including different measures, each calculated on the basis of the frequency with which bigrams and trigrams present in the test strings appeared in the learning strings) were manipulated independently in the test phase of an artificial grammar learning task. When participants learned few items of the grammar (Experiments 1a and 2a), the associated items were more often classified as grammatical than the nonassociated ones. On the other hand, when the learning phase included most of the grammatical items (Experiments 1b and 2b), the only effect observed was an effect of grammaticality. These results suggest that, depending on the specific constraints of the tasks, knowledge based on bigrams and trigrams and knowledge based on the abstraction of the grammatical structure can be used for the classification task. [less ▲]

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See detailTiming effect of combined radioimmunotherapy and radiotherapy on a human solid tumor in nude mice.
Coucke, Philippe ULg; Lin-Quan, Sun; Vogel, Charles-André et al

in Cancer Research (1997), 57

Timing effects of radioimmunotherapy (HIT) combined with external beam radiotherapy (RT) were assessed In human colon carcinoma xe nografts. Initially, dose effects offractlonated RT and RIT were ... [more ▼]

Timing effects of radioimmunotherapy (HIT) combined with external beam radiotherapy (RT) were assessed In human colon carcinoma xe nografts. Initially, dose effects offractlonated RT and RIT were evaluated separately. Then, 30 Gy RT (10 fractions over 12 days) were combined with three weekly Lv. injections of 200 g@Ci of 131I-labeled anti-carcino embryonic antigen monoclonal antibodies in four different treatment schedules. RIT was given either prior to, concurrently, Immediately after, or 2 weeks after RT administration. The longest regrowth delay (RD) of 105 days was observed in mice treated by concurrent administration of RT and lilT, whereas the RDs of RT and RIT alone were 34 and 20 days, respectively. The three sequential combination treatments produced sig nificantly shorter RDs ranging from 62 to 70 days. The tumor response represented by the minimal volume (MV) also showed that concurrent administration of RT and RIT gave the best result, with a mean MV of 4.5% as compared to MVs from 26 to 53% for the three sequential treatments. The results were confirmed In a second experiment, In which a RT of 40 Gy was combined with an identical lilT as above (three injections of 200 g&Ci of ‘31I-labeled monoclonal antibodies). At compa rable toxicity levels, the maximum tolerated RT or BIT alone gave shorter RDs and less tumor shrinkage compared to slinultaneous RT+RIT. These results may be useful for designing clinical protocols ofcombined RIT and RT. [less ▲]

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See detailRegolazione della crescité follicolare e luteinica. Ovulazione, corpo luteo e luteolisi
Drion, Pierre ULg; Ectors, Fabien; Hanzen, Christian ULg et al

in Riproduzione dei Ruminanti (1997), 14(9), 17-25

Most ovarian follicles (99.9%) will end up with follicular atresia. During antral stages atresia depends on a reduction of FSH levels secondary to estradiol and inhibin secretions by the dominant follicle ... [more ▼]

Most ovarian follicles (99.9%) will end up with follicular atresia. During antral stages atresia depends on a reduction of FSH levels secondary to estradiol and inhibin secretions by the dominant follicle. Plasma levels in estradiol higher than 12pg/ml for at least 12 hours in bovine will cause the reversal of the negative feed-back effect of estradiol on the hypothalamus inducing the preovulatory peak of LH. So that the ovulatory discharge does not occur prematurely, the dominant follicle also secretes GnSIF which desensitises the hypohtesis to the action of GnRH. After ovulation, the corupus luteum, a true endocrine gland, develops. [less ▲]

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See detailIntensivemedizinische Probleme nach kardiochirurgischen Eingriffen in der Neugeborenenperiode
Hörnchen, H.; Dreuw, M.; Merz, U. et al

in Monatsschrift fur Kinderheilkunde (1997), 145

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See detailPhosphorylation of the Bovine Leukemia Virus transactivator p34Tax is required for transformation but not for transactivation.
Kettmann, Richard ULg; Grimonpont, C.; Kerkhofs, Pierre et al

in FASEB Journal (1997), 11(9), 1179

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See detailLes pesticides: effets endocriniens et cancérogènes chez l'Homme
Charlier, Corinne ULg; Plomteux, Guy ULg

in Toxicorama (1997), IX

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See detailLuteinizing hormone increases the abundance of various transcripts, independently of the androgens, in the rat prostate.
Reiter, E.; Poncin, Joseph ULg; Hennuy, Benoît ULg et al

in Biochemical and Biophysical Research Communications (1997), 233(1), 108-12

Differential display analysis was carried out to find, in the rat prostate, genes that could be regulated by Luteinizing Hormone (LH), independently of the androgens. Hypophysectomized and castrated adult ... [more ▼]

Differential display analysis was carried out to find, in the rat prostate, genes that could be regulated by Luteinizing Hormone (LH), independently of the androgens. Hypophysectomized and castrated adult rats were treated with either LH, testosterone or saline. Regulated discrete bands have been eluted and reamplified. After Northern blotting, the levels of mRNA corresponding to 8 PCR fragments were significantly increased by LH treatment. None of these inserts were found to be induced by testosterone. One insert was subcloned, sequenced and identified as the ribosomial protein S 23. A competitive RT-PCR assay was carried out on the full length S 23 cDNA and confirmed that its mRNA levels were stimulated by LH but not by testosterone. These results strongly suggest that the LH membrane receptor, previously shown to be expressed in the rat prostate, has a physiological significance in this organ. Moreover, it appears that the effect of LH on the rat prostate are independent of the androgens. [less ▲]

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See detailBicuculline methiodide potentiates NMDA-dependent burst firing in rat dopamine neurons by blocking apamin-sensitive Ca2+-activated K+ currents.
Johnson, S. W.; Seutin, Vincent ULg

in Neuroscience Letters (1997), 231(1), 13-6

Apamin, a bee venom toxin which blocks a Ca2+-dependent K+ current, potentiates N-methyl-D-aspartate (NMDA)-induced burst firing in dopamine neurons. We now report that burst firing is also potentiated by ... [more ▼]

Apamin, a bee venom toxin which blocks a Ca2+-dependent K+ current, potentiates N-methyl-D-aspartate (NMDA)-induced burst firing in dopamine neurons. We now report that burst firing is also potentiated by an apamin-like effect of bicuculline methiodide (BMI) at the same concentration (30 microM) which blocks GABA(A) receptors in vitro. Using microelectrodes to record intracellularly from rat dopamine neurons in the midbrain slice, BMI reduced the apamin-sensitive afterhyperpolarization in all cells tested. BMI also mimicked apamin (100 nM) by potentiating burst firing produced by a concentration of NMDA (10 microM) which is too low to evoke burst firing when perfused alone. When recording under voltage-clamp, both BMI and apamin reduced a depolarization-activated outward current which was also sensitive to perfusate containing no-added Ca2+. Although picrotoxin (100 microM) and bicuculline free base (30 microM) blocked the inhibition of firing produced by the GABA(A) agonist isoguvacine (100 microM), neither had apamin-like effects. We conclude that BMI potentiates burst firing by blocking an apamin-sensitive Ca2+-activated K+ current. [less ▲]

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See detailActes de la 23ème Réunion internationale de l'AMDP francophone, Colonster (Liège), 1er et 2 septembre 1995
Mormont, Christian ULg

in Acta Psychiatrica Belgica (1997), 97(Suppl. 1), 1-72

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See detailQuelle est la place de l’Université dans notre société ?
Brunet, Sébastien ULg

in Revue l’Observatoire (1997), 15

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See detailEtude clinique et anatomopathologique de l'infection expérimentale de lapins par une souche virale amyxomateuse isolée en Belgique
Marlier, Didier ULg; Coignoul, Freddy ULg; Boucraut-Baralon, Corine et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailLa problématique de la matière grasse : aspects théoriques
Thonart, Philippe ULg; Destain, Jacqueline ULg; Antoine, P. et al

in Tribune de l'Eau (La) (1997), 586/2

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See detailIUG-/ZOUG- dans une inscription latine écrite en lettres grecques (CIJ I 215)
Rochette, Bruno ULg

in Zeitschrift für Papyrologie und Epigraphik (1997), 115

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See detailLe rôle de l'officier de l'état civil requis de célébrer un mariage présumé simulé
Paris, Catherine ULg

in Revue Trimestrielle de Droit Familial (1997)

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See detailLe rôle de l'expert
Boxho, Philippe ULg

in Société d'étude du dommage corporel (1997)

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See detailSchool Geography Textbooks in Francophone Belgium
Merenne-Schoumaker, Bernadette ULg

in International Research in Geographical & Environmental Education (1997), 6(1), 86-88

Review on the situation of geographical textbooks in Belgium since the French education reform in 1969

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See detailGénération innommable
Demoulin, Laurent ULg

in Textyles : Revue des Lettres Belges de Langue Française (1997), 14

Evocation de tendances romanesque ayant émergé dans les années 1980 et 1990 envisagées au moyen des notions discutables et discutées de "minimalisme" et de "postmodernité".

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See detailHooliganisme: la délinquance des stades de football
Comeron, Manuel ULg

in Déviance et Société (1997), 21(1), 97-113

Analyse de la violence des supporters: individuelle, groupale, foule et sociétale.

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See detailLa Belgique: Diversité territoriale
Merenne-Schoumaker, Bernadette ULg; Van der Haegen, H.; Van Hecke, E.

in Bulletin du Crédit Communal (1997), (202), 144

Présentation synthétique en 16 thèmes des résultats des recherches d'équipes universitaires de la KULeuven, l'UCL, l'ULB, la VUB et l'ULg. Tableau de la situation de la Belgique en 1991 et des dynamiques ... [more ▼]

Présentation synthétique en 16 thèmes des résultats des recherches d'équipes universitaires de la KULeuven, l'UCL, l'ULB, la VUB et l'ULg. Tableau de la situation de la Belgique en 1991 et des dynamiques entre 1981 et 1991. 155 cartes en couleurs. [less ▲]

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See detailFreeze-dried resorcinol-formaldehyde gels
Blacher, Silvia ULg; Pirard, René ULg; Pirard, Jean-Paul ULg et al

in Journal of Non-Crystalline Solids (1997), 212(2-3), 250-261

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer ... [more ▼]

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer to micrometer length-scale. Taking a standard freezing rate, we study in detail the influence of the molar ratio resorcinol/catalyst on the texture, This molar ratio is one of the parameters under consideration which can lead to a tailoring of the dried gel texture in order to develop adsorbents or catalyst supports of controlled porosity. Characterization methods include nitrogen adsorption-desorption (including the classical and the fractal interpretations), mercury porosimetry, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and small angle X-ray scattering (SAXS). [less ▲]

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See detailEn mai élis qui te plaît
Durand, Pascal ULg

in Liège Université (1997), (été), 3

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See detailL'interprétation communautaire de la notion de défendeur défaillant au sens de l'article 27, point 2, de la Convention de Bruxelles
Boularbah, Hakim ULg

in Revue de Droit Commercial Belge [= RDC] = Tijdschrift voor Belgisch Handelsrecht [=TBH] (1997)

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See detailLe clonage par transfert de noyau dans l'espèce bovine
Ectors, Fabien ULg; Delval, Alain; Beckers, Jean-François ULg et al

in Annales de Médecine Vétérinaire (1997), 141

A all in vitro cloning technique was developed in wich embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer (re-cloning). Such method ... [more ▼]

A all in vitro cloning technique was developed in wich embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer (re-cloning). Such method permitted to produce 14,5% of morulae and 14,9% of blastocysts after the first and second cycle of nuclear transfer, respectively. The rates of birth obtained after transfer of such embryos were 21,4% and 20,5% for first and second cyle respectively, corresponding to 6 and 5 calves for 28 and 24 transferred embryos. Unfortunately, gestation patholgies and an increase of birth weights were observed. It seems that the in vitro presence of gametes and/or embryos may be responsible of an alteration in the control of gene expression. [less ▲]

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See detailEffect of diet and bST on mRNA for IGF-I binding proteins (BP)-2 and -3 in dairy cattle
Sharma, B. K.; Vandehaar, M. J.; Tucker, H. A. et al

in Journal of Dairy Science (1997), 80(suppl 1), 176

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See detailEntre Babil et Babel
Durand, Pascal ULg

in Liège Université (1997), (Automne), 15

Compte rendu de J.-A. Rondal et J.-P. Thibaut, Psychologie de l'enfant et de l'adolescent, Bruxelles, Labor, 1997

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See detailRecherche d'information et pragmatisme : I. Le paradigme de la confirmation d'hypothèses
Dardenne, Benoît ULg; Leyens, J.; Yzerbyt, V. Y.

in Année Psychologique (L') (1997), 97

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See detailJungermannia paroica (Schiffn.) Grolle in the Vosges, new to France
Vanderpoorten, Alain ULg; Sotiaux, André ULg

in Journal of Bryology (1997), 19

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See detailAnti-PMSG in sheep subjected annualy to oestrus synchronisation
Bodin, L.; Drion, Pierre ULg; Remy, Benoit et al

in Reproduction Nutrition Development (1997), 37

Estimation of the long-term consequences on reproduction performance of the oestrus synchronisation treatments that are annually applied to ewes was carried out on nine officially controlled dairy flocks ... [more ▼]

Estimation of the long-term consequences on reproduction performance of the oestrus synchronisation treatments that are annually applied to ewes was carried out on nine officially controlled dairy flocks in the Roquefort region of France. A hormonal treatment combining the insertion of a vaginal fluoro-gestone acetate (FGA) sponge for 14 days and the injection of about 500 IU of pregnant mare serum gonadotropin (PMSG) at withdrawal was applied to the ewes in seven of the nine flocks. The ewes in the two other flocks were used as controls. Blood samples were taken from each female just before the treatment (to test for the presence of residual antibodies) and 20 days after the PMSG injection. Anti-PMSG antibody binding rates were calculated for each blood sample. The residual binding rate increased with age and induce negative effects on the following years reproduction performances, ie, they increased the probability that the ewes would not become pregnant. [less ▲]

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See detailBilinguisme, traduction et histoire des textes dans l'Orient grec (Ier - IVe s. après J.-C.)
Rochette, Bruno ULg

in Revue d'Histoire des Textes (1997), 27

Vise à montrer l'intérêt que présentent les textes traduits pour l'étude de la transmission de l'original. Trois exemples de traductions du latin en grec, réalisées dans la Pars Orientis entre le Ier et ... [more ▼]

Vise à montrer l'intérêt que présentent les textes traduits pour l'étude de la transmission de l'original. Trois exemples de traductions du latin en grec, réalisées dans la Pars Orientis entre le Ier et le IVe s., sont étudiés : les Res gestae diui Augusti, les listes de mots compilées à partir de Virgile et de Cicéron sur papyrus, la uersio Graeca de la quatrième Bucolique de Virgile appartenant à l'Oratio ad Sanctorum coetum de Constantin le Grand. L'apport de ces traductions se situe sur deux plans. D'abord, constituant une tradition en soi, les traductions grecques d'œuvres latines permettent de connaître l'état du texte au moment de sa traduction et peuvent donc jouer un rôle dans l'ecdotique. Ensuite, ces traductions apportent une contribution à l'histoire de la littérature et des mentalités. La traduction d'un texte se situe dans un contexte culturel différent de celui dans lequel a été élaboré l'original. Loin de se contenter de traduire ad uerbum, le traducteur fait passer dans la version traduite des conceptions nouvelles, politiques, sociales ou religieuses. Ainsi, par exemple, le passage d'un régime politique à un autre (République-Empire) ou d'une conception religieuse à une autre (paganisme-christianisme) peut modifier radicalement la perspective du traducteur. [less ▲]

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See detailBulletin bibliographique de la Société Rencesvals, 1996-1997
Horrent, Jacques ULg; Henrard, Nadine ULg

in Bulletin bibliographique de la Société Rencesvals (1997), (28), 189

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See detailPlasma pregnancy-associated glycoprotein and progesterone concentrations in pregnant Assaff ewes carrying single and twin lambs
Ranilla, Marie-José; Sulon, Joseph ULg; Mantecón, A. R. et al

in Small Ruminant Research (1997), 24(2), 125-131

Ovine pregnancy-associated glycoprotein (oPAG) and progesterone (P4) concentrations were monitored weekly during the last three months of gestation and the first month postpartum in plasma of twelve Assaf ... [more ▼]

Ovine pregnancy-associated glycoprotein (oPAG) and progesterone (P4) concentrations were monitored weekly during the last three months of gestation and the first month postpartum in plasma of twelve Assaf ewes. The oPAG levels were determined with a heterologous RIA using bovine PAG as standard and tracer and rabbit antiserum against oPAG. The P4 levels were measured with a radioimmunological procedure with a sensitivity to less than 0.1 ng/ml. The oPAG profiles in ewes carrying a single lamb and in those carrying twins were very similar from week 9 of gestation to lambing. Ewes which had twins presented numerically higher oPAG concentrations from week 12 to lambing, but that difference was only significant (p<0.05) at week 21. Ewes carrying twins presented higher (P<0.05) P4 concentrations from weeks 12 to 20 of gestation than those carrying a single lamb, but afterwards there was no difference. No correlation was found between P4 and oPAG concentrations at each stage of gestation studied in any group. After lambing, P4 levels dropped rapidly in one week, whereas oPAG decreased in four weeks to basal values in both groups of ewes. No relationship (P>0.05) was found between oPAG concentrations and lamb birth-weight at any week of gestation considered in this study. However, the lamb birth-weight was positively correlated (P<0.10) with the P4 concentrations from weeks 9 to 19 of gestation. Results indicate that number of fetuses could influence the oPAG production in ewes during the last three months of gestation. [less ▲]

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