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See detailLa compétence du juge des référés en cas de procédure d'extradition
Kefer, Fabienne ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1993)

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See detailTests simples pour le diagnostic présumé des Escherichia coli isolées principalement chez les bovins et productrices des cytotoxines nécrosantes (CNF)
Pohl, P.; Oswald, E.; Van Robaeys, G. et al

in Annales de Médecine Vétérinaire (1993), 137

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See detailDu bon steak et du bon lait: d'abord interroger le naturel et en percer tous ces secrets
Renaville, Robert ULg; Burny, Arsène; Portetelle, Daniel ULg

in Agricontact (1993), 255

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See detailUltrastructural distribution of DNA within the ring-shaped nucleolus of human resting T lymphocytes.
Vandelaer, M.; Thiry, Marc ULg; Goessens, Guy ULg

in Experimental Cell Research (1993), 205(2), 430-2

The precise distribution of DNA within the resting human T lymphocyte nucleolus has been investigated, at the ultrastructural level, by cytochemical and molecular immunocytochemical techniques. The ... [more ▼]

The precise distribution of DNA within the resting human T lymphocyte nucleolus has been investigated, at the ultrastructural level, by cytochemical and molecular immunocytochemical techniques. The nucleolus is partially enveloped by a layer of condensed chromatin which, at several places, penetrates into the nucleolar body until in close contact with the fibrillar centers. Morphometric analysis reveals that 32% of the fibrillar center surface is essentially occupied by condensed chromatin. Using the in situ terminal deoxynucleotidyl transferase-immunogold procedure for detecting DNA, we further show that evident label is exclusively found over the condensed chromatin and over the fibrillar centers, whereas no significant label is detected over the dense fibrillar component of the nucleolus. [less ▲]

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See detailEngery-filtering transmission electron microscopy of biological specimens.
de Bruijn, W. C.; Sorber, C. W.; Gelsema, E. S. et al

in Scanning Microscopy (1993), 7(2), 693-708709

By energy-filtering transmission electron microscopy (EFTEM) electrons can be separated by their energy losses. An electron-energy filter, added to the microscope column allows the measurement of the ... [more ▼]

By energy-filtering transmission electron microscopy (EFTEM) electrons can be separated by their energy losses. An electron-energy filter, added to the microscope column allows the measurement of the energy distribution of transmitted electrons that have lost energy (< 2,000 eV, with an energy resolution of approximately 1 eV). These filtered electrons, recorded either as a spectrum or as an image, are composed of two parts superimposed on top of each other: (a) the unspecific energy-loss population (= the continuum) and (b) the specific element-related energy-loss population (= the edges). At the edges, electron data in spectra and images are mathematically processed, to obtain the desired element-related net-intensity values or images. These data are related to the total transmitted electron intensity, from the zero- and low-loss spectral region giving the relative spectralor image intensity rations ((S)R*x, (I)R*x), which can be related to the element concentration. The acquisition of the zero-loss and low-loss data is hampered by the restricted dynamic range of the TV camera. By improvements through the introduction of calibrated attenuation filters in the optical path to the TV-camera, more reliable values for (S)R*x and (I)R*x can be acquired. By addition of Bio-standards adjacent to the tissue, a "known" and "unknown" concentration of the element present in the same ultrathin section and the "bias" in the concentration estimation, can be obtained. Some practical examples are given for the estimation of the iron cencentration in siderosomes, boron in melasosomes and calcium in calcium oxalate monohydrate crystals. [less ▲]

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See detailEscherichia coli producing CNF1 and CNF2 cytotoxins in animals with different disorders
Pohl, P.; Oswald, E.; Van Muylem, K. et al

in Veterinary Research (1993), 24

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See detailPurification Of Antifungal Lipopeptides By Reversed-Phase High-Performance Liquid-Chromatography
Razafindralambo, Hary ULg; Paquot, Michel ULg; Hbid, Choukri et al

in Journal of Chromatography. A (1993), 639(1), 81-85

A rapid procedure for the purification of antifungal lipopeptides from Bacillus subtilis, a potential agent for biocontrol of plant diseases, was tested. It consists of a solid-phase extraction on C18 gel ... [more ▼]

A rapid procedure for the purification of antifungal lipopeptides from Bacillus subtilis, a potential agent for biocontrol of plant diseases, was tested. It consists of a solid-phase extraction on C18 gel followed by reversed-phase chromatography using a biocompatible PepRPC HR 515 column with a pharmacia fast protein liquid chromatographic system. This is a very effective method for isolating and fractionating iturin A and surfactin, two lipopeptides of different nature, co-produced by Bacillus subtilis strain S499. The presence of homologous lipopeptides was easily detected. [less ▲]

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See detailResistance a la secheresse et reponses a l'acide abscissique: analyse d'une approche synthetique.
El-Jaafari, S.; Paul, Roger ULg; Lepoivre, Philippe ULg et al

in Cahiers Agricultures (1993), 2(4),

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See detailRaoul de Cambrai.
Moreno, Paola ULg

in Revue Belge de Philologie et d'Histoire (1993)

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See detailMR1240747,Hromadka, II, Theodore V.,The best approximation method in computational mechanics
Rochus, Pierre ULg

in Mathematical Reviews [=MR] (1993)

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See detailIsopyoverdin Pp BTP1, a biogenetically interesting novel siderophore from Pseudomonas putida
Jacques, Philippe; Gwose, Inga; Seinsche, Dieter et al

in Natural Product Letters (1993), 3

From the cultures of Pseudomonas putida BTP 1 a siderophore could be isolated which contains the chromophore 2a rather than 1a typical for pyoverdins. Its structure was elucidated by MS, NHR and chemical ... [more ▼]

From the cultures of Pseudomonas putida BTP 1 a siderophore could be isolated which contains the chromophore 2a rather than 1a typical for pyoverdins. Its structure was elucidated by MS, NHR and chemical degradation. This new structural type is of great interest. The currently accepted biogenetic pathway leading to 1a starts from D-Tyr and L-Dab which condense to give the ferribactin chromophore 4. Subsequent ring closure via the -nitrogen of Dab leads to 1a while alternative ring closure via the -nitrogen would yield 2a. It is for the first time that this iso-chromophore has been detected in a Pseudomonas siderophore. Its discovery confirms the assumed intermediacy of ferribactine in the biogenesis of pyoverdins. [less ▲]

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See detailOstéoporose postménopausique: le point sur la thérapeutique
Reginster, Jean-Yves ULg

in Medisearch (1993), 73

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See detailSequence of the triosephosphate isomerase-encoding gene isolated from the thermophile Bacillus stearothermophilus
Rentier-Delrue, Françoise ULg; Moyens, Sylvianne; Lion, Michelle ULg et al

in Gene (1993), 134(1), 137-8

By analysis of genomic clones, we have determined the complete nucleotide sequence of the gene encoding triosephosphate isomerase (TIM; EC 5.3.1.1) in the thermophilic bacterium, Bacillus ... [more ▼]

By analysis of genomic clones, we have determined the complete nucleotide sequence of the gene encoding triosephosphate isomerase (TIM; EC 5.3.1.1) in the thermophilic bacterium, Bacillus stearothermophilus. The gene encodes a 253-amino-acid TIM which is 39% identical to that of the mesophile, Escherichia coli. [less ▲]

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See detailStereoselective hydrogenation of methacycline to doxycycline catalysed by rhodium-carborane complexes
Pirotte, Bernard ULg; Felekidis, Apostolos ULg; Fontaine, M. et al

in Tetrahedron Letters (1993), 34

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See detailEvolution du relief au Niger occidental : rôle de la fracturation du socle précambrien et de la formation de pseudo-karsts au sein de la lithomarge et de la couverture sédimentaire
Willems, Luc ULg; Lenoir, François; Levecq, Jean-Marie et al

in Comptes-Rendus de l'Académie des Sciences de Paris (1993), 317(Série II), 97-102

The observation of several forms in the Precambrian formations, in Tertiary and Quaternary deposits brings us to propose a model of topographic evolution mainly generated by a pseudo-karst. This latter is ... [more ▼]

The observation of several forms in the Precambrian formations, in Tertiary and Quaternary deposits brings us to propose a model of topographic evolution mainly generated by a pseudo-karst. This latter is developed in sedimentary deposits and in the lithomargin, in relation with fracturation of the basement. [less ▲]

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See detailRole of Neuropeptides in Acetylcholine-Induced Edema in Isolated and Perfused Rabbit Lungs
Delaunois, Annie ULg; Gustin, Pascal ULg; Ansay, Michel ULg

in Journal of Pharmacology and Experimental Therapeutics (The) (1993), 266(2), 483-491

Changes in pulmonary endothelial permeability and in microvascular hemodynamics in response to cumulative concentrations of acetylcholine (ACh) (10(-8) M to 10(-5) M) were investigated in isolated ... [more ▼]

Changes in pulmonary endothelial permeability and in microvascular hemodynamics in response to cumulative concentrations of acetylcholine (ACh) (10(-8) M to 10(-5) M) were investigated in isolated, perfused rabbit lungs. The total pressure gradient was partitioned into four components: arterial, pre- and postcapillary and venous. The capillary filtration coefficient (Kf, c) also was evaluated. ACh caused a significant increase in arterial and precapillary pressures at concentrations higher than 3 x 10(-6) M. The total pressure gradient and precapillary were significantly increased whereas arterial, postcapillary and venous pressure gradient remained unchanged. In papaverine (3 x 10(-4) M)-pretreated lungs, the vasoconstriction was abolished and a concentration-dependent increase in Kf,c was recorded from 10(-8) to 10(-5) M ACh. This reaction was accompanied by pulmonary edema. Atropine, indomethacin, aspirin, ketanserin, clonidine, morphine and (+/-)-CP 96-345, an antagonist of neurokinin NK1 receptors, completely prevented the effects of ACh on Kf,c. In contrast, cromolyn sodium and SR48968, a neurokinin NK2 antagonist, did not inhibit the response to ACh. Terfenadine together with cimetidine had a partially inhibitory effect. Changes in the Kf, c similar to those observed with ACh were induced by capsaicin (10(-4) M) by exogenous substance P (10(-7) M) and by 5-hydroxytryptamine (5-HT) (10(-4) M). The effects of SP were inhibited by aspirin, (+/-)-CP 96,345 and ketanserin, but not by atropine and antihistaminics. 5-HT effects were prevented by aspirin and not by (+/-)-CP 96,345. It was concluded that ACh-induced pulmonary edema was due to an increase in the capillary filtration coefficient.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailTuméfaction de la jambe à Neocosmospora vasinfecta chez un transplanté rénal. Premier cas d'infection humaine
Chandenier, Jacques; Hayette, Marie-Pierre ULg; de Bièvre, Claude et al

in Journal de Mycologie Médicale (1993), 3

A 46-year old man, originated from Senegal, but living in France for more than 15 years, is dialized since January 1989, because of renal insuficiency. He had undergone a kidney graft in October 1990 with ... [more ▼]

A 46-year old man, originated from Senegal, but living in France for more than 15 years, is dialized since January 1989, because of renal insuficiency. He had undergone a kidney graft in October 1990 with good initial evolution, without any graft rejection. The immunosuppressive tretment quite moderate, was prenisone 10mg/d, azathioprine 50 mg/d and ciclosporine 400mg/d. On the 8th month, a tumefaction affecting the anterior side of the left leg was discovered, which was thick, renitent and non inflammatory. It relapsed after two punctures. In both cases direct examination showed numerous hyphae and a fungus identified as Neocosmospora vasinfecta, was isolated by culture:it is the sexual form of an Ascomycete whose species name is not identified. The treatment associated a complete surgery and ketoconazole during a week (200mg/d) The tumor did not relapsed after a 30 months follow up. [less ▲]

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See detailApplying the Meridional Streamfunction Visualization Technique to Open Ocean Domains
Deleersnijder, E.; Beckers, Jean-Marie ULg

in Ocean Modelling (1993), 101

It is common practice to represent by streamfunction the transport field ensuing from the integration - over one horizontal coordinate - of the velocity field predicted by ocean models. This very useful ... [more ▼]

It is common practice to represent by streamfunction the transport field ensuing from the integration - over one horizontal coordinate - of the velocity field predicted by ocean models. This very useful visualization technique requires that the transport field be divergenceless. If this is not the case, it is suggested to extract the divergenceless transport field that is closest to that stemming from the model while verifying the impermeability conditions of the ocean surface and bottom. A variational approach is examined. [less ▲]

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See detailLa descendance de celt. *AKARNOS en wallon
Boutier, Marie-Guy ULg

in Revue de Linguistique Romane (1993)

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See detailDémocratie, discussion et écriture chez Habermas et Lyotard
Delruelle, Edouard ULg

in Cahiers Internationaux de Symbolisme (1993), 74-76

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See detailLa decharge egale un bioreacteur a gerer.
Dumont, M.; Taillieu, X.; Destain, Jacqueline ULg et al

in Tribune de l'Eau (La) (1993), 46(564), 3-10

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See detailSédimentologie et diagenèse des monticules micritiques "F2j" du Frasnien de l'Ardenne
Boulvain, Frédéric ULg

in Professional Paper Belgian Geological Survey (1993), 260(1 et 2), 1-427

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See detailSaving behavior in 17 OECD countries
Kessler, Denis; Pestieau, Pierre ULg; Perelman, Sergio ULg

in Review of Income and Wealth (1993), (39), 37-50

This article compares savings behavior in a sample of 17 OECD countries over 24 years. On the basis of an analysis of variance and of a life-cycle-hypothesis-based equation, we test the homogeneity of ... [more ▼]

This article compares savings behavior in a sample of 17 OECD countries over 24 years. On the basis of an analysis of variance and of a life-cycle-hypothesis-based equation, we test the homogeneity of households' savings behavior. It appears that one cannot really speak of a homogeneous saving behavior across countries. This is a relevant finding in times of increasing economic and financial integration. [less ▲]

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See detailEffects of Age and Indomethacin on Response and Sensitivity of Pulmonary Artery to Phenylephrine and to Histamine in Pigs
Gustin, Pascal ULg; Ansay, Michel; Advenier, C.

in Journal of Veterinary Pharmacology & Therapeutics (1993), 16(2), 207-213

The vasoconstrictor effects of phenylephrine and histamine were investigated in isolated strips of pulmonary arteries in pigs during ageing. Interactions between phenylephrine-induced responses and ... [more ▼]

The vasoconstrictor effects of phenylephrine and histamine were investigated in isolated strips of pulmonary arteries in pigs during ageing. Interactions between phenylephrine-induced responses and arachidonic acid derivatives were also studied by incubating the blood-vessels with indomethacin. Potency (pD2 values) and maximal effects (Emaxx) recorded in 5-week-old piglets (group I, n= 5) with phenylephrine [5.71 ± 0.17 and 0.76 ± 0.22 g/mg of dry tissue respectively (mean ± SEM)] were similar to values found in 12-week-old animals (group 2, n = 5) (5.49 ± 0.30 and 1.06 ± 0.27 g/mg of dry tissue respectively). The sensitivity and responsiveness of tissues to this agonist were significantly reduced in 26-week-old mature pigs (group 3, n = 6) as indicated by the decrease in pD2 (3.91 ± 0.23; P < 0.01) and Emax (0.27 ± 0.13 g/mg of dry tissue; P < 0.05) values observed in this group. Histamine (10_3M)-induced maximal responses (Emax) were significantly higher in group 2 (2.23 ± 0.49 g/mg) than in group 1 (0.85 ± 0.11 g/mg; P < 0.05) and in group 3 (0.48 ± 0.10 g/mg; P < 0.01). In 5-week-old animals, indomethacin (3.10˜5M) significantly (P < 0.05) shifted the concentration-response curve to phenylephrine to the right (0.28 log. units) and depressed contractions to this drug as shown by the significant decrease of 39.5% (P < 0.05) in Emax. This cyclo-oxygenase inhibitor had no effect in other groups. These data indicate that phenylephrine is a potent and effective vasoconstrictor agent for the main pulmonary arteries in 5-week-old piglets and that alpha-1-adrenergic-induced contractions are enhanced by cyclo-oxygenase products. These findings can be related with the high reactivity of pulmonary vascular smooth muscles in these animals [less ▲]

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See detailThiamine Triphosphate Activates an Anion Channel of Large Unit Conductance in Neuroblastoma Cells
Bettendorff, Lucien ULg; Kolb, Hans-Albert; Schoffeniels, E.

in Journal of Membrane Biology (1993), 136(3), 281-8

In neuroblastoma cells, the intracellular thiamine triphosphate (TTP) concentration was found to be about 0.5 microM, which is several times above the amount of cultured neurons or glial cells. In inside ... [more ▼]

In neuroblastoma cells, the intracellular thiamine triphosphate (TTP) concentration was found to be about 0.5 microM, which is several times above the amount of cultured neurons or glial cells. In inside-out patches, addition of TTP (1 or 10 microM) to the bath activated an anion channel of large unit conductance (350-400 pS) in symmetrical 150 mM NaCl solution. The activation occurred after a delay of about 4 min and was not reversed when TTP was washed out. A possible explanation is that the channel has been irreversibly phosphorylated by TTP. The channel open probability (Po) shows a bell-shaped behavior as a function of pipette potential (Vp). Po is maximal for -25 mV < Vp < 10 mV and steeply decreases outside this potential range. From reversal potentials, permeability ratios of PCl/PNa = 20 and PCl/Pgluconate = 3 were estimated. ATP (5 mM) at the cytoplasmic side of the channel decreased the mean single channel conductance by about 50%, but thiamine derivatives did not affect unit conductance; 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (0.1 mM) increased the flickering of the channel between the open and closed state, finally leading to its closure. Addition of oxythiamine (1 mM), a thiamine antimetabolite, to the pipette filling solution potentiates the time-dependent inactivation of the channel at Vp = -20 mV but had the opposite effect at +30 mV. This finding corresponds to a shift of Po towards more negative resting membrane potentials. These observations agree with our previous results showing a modulation of chloride permeability by thiamine derivatives in membrane vesicles from rat brain. [less ▲]

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See detailUne logique de l'anorexie mentale
Servais, Véronique ULg

in Revue Internationale de Systémique (1993), 7(4), 385-418

The paper presents a batesonian approach of anorexia nervosa. The illness is viewed as a positive feedback loop. The first restrictions appear as a solution to diverse problems of adolescence. Then the ... [more ▼]

The paper presents a batesonian approach of anorexia nervosa. The illness is viewed as a positive feedback loop. The first restrictions appear as a solution to diverse problems of adolescence. Then the restrictions become a deutero-learning : the girl finds pleasure and security in restriction behaviours. She si permanently looking for challenging contexts where she can proof her self control. Because the control is a deutero-learning the behavior cannot be diminished through punishment. Only the restoration of relationships with the whole personnality and the environment can give the girl the therapeutic experience of becoming to as system that she cannot control. [less ▲]

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See detailEffect of prolactin on alpha and beta chloride cells in the gill epithelium of the saltwater adapted tilapia " Oreochromis niloticus"
Pisam, B.; Auperin, B.; Prunet, P. et al

in Anatomical Record (1993), 235

Tilapia (Oreochromis niloticus), 21 g average body weight, were divided into two groups. A group was maintained in fresh water, whereas another group was adapted for 2 weeks to 20% salt water. Among the ... [more ▼]

Tilapia (Oreochromis niloticus), 21 g average body weight, were divided into two groups. A group was maintained in fresh water, whereas another group was adapted for 2 weeks to 20% salt water. Among the latter, fishes were injected every 2 days for a week with tilapia prolactin (ti-PRL I). Gills were prepared for electron microscopy in order to determine the types and surface areas of chloride cells in each experimental condition. Two types of chloride cells, the alpha and beta cells were easily distinguished on the basis of their location and ultrastructural features in the gills of freshwater fishes, while only one type of cell, the saltwater alpha cells presumably derived from the transformation of the freshwater alpha cells, were encountered in saltwater adapted animals. After PRL injection of saltwater adapted fishes, small chloride cells, which displayed ultrastructural features similar to those of beta cells in freshwater tilapia, reappeared in interlamellar regions of the gills. In the same experimental conditions, the voluminous saltwater alpha cells showed a tendency to resume ultrastructural features more characteristic of the freshwater alpha cells from which they were derived. These observations tend to indicate that prolactin behaves as a "freshwater adapting hormone" and that beta cells are specifically involved in fish adaptation to freshwater living conditions. [less ▲]

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See detailTHERMAL-CONDUCTIVITY OF TWINNED YBA2CU3O7-X AND TWEEDED YBA2(CU0.95FE0.05)3O7-X IN A MAGNETIC-FIELD - EVIDENCE FOR INTRINSIC PROXIMITY EFFECT
Bougrine, Hassan ULg; SERGEENKOV, S.; Ausloos, Marcel ULg et al

in Solid State Communications (1993), 86(8), 513-516

The behavior of the thermal conductivity kappa of twinned YBa2Cu3O7-x and tweeded YBa2(Cu0.95Fe0.05)3O7-x polycrystals in a magnetic field up to 5 T is presented. Data as a function of field are shown to ... [more ▼]

The behavior of the thermal conductivity kappa of twinned YBa2Cu3O7-x and tweeded YBa2(Cu0.95Fe0.05)3O7-x polycrystals in a magnetic field up to 5 T is presented. Data as a function of field are shown to depart from the usual linear behavior of thermal magnetoresistivity (TMR) kappa-1 (B) for conventional superconductors. A set of stretched exponential laws, of the form kappa-1 (B) - kappa-1 (0) = CB exp(-pB(q)) has been found to describe our data with q decreasing with temperature from 1 to 1/2 and from 1/2 to 1/4 for pure and iron-doped samples, respectively, in contrast to the unique interpolation formula (q = 1/4) for TMR proposed recently by Richardson et al. [1] to fit their data on twinned and untwinned single crystals. Such a complex behavior of TMR in the high field region is supposed to originate from extended defect mediated intrinsic proximity effect in both samples. The proposed interpretation is based on incorporating two types of phonon scatterers, free (unpinned) and pinned (by the defect cores) vortices, into a conventional picture of phonon-vortex scattering mechanism. [less ▲]

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See detailEffects of a 1-year treatment with a low-dose combined oral contraceptive containing ethinyl estradiol and cyproterone acetate on glucose and insulin metabolism.
Scheen, André ULg; Jandrain, Bernard ULg; Humblet, Dominique ULg et al

in Fertility and Sterility (1993), 59(4), 797-802

OBJECTIVE: To study the effects of the slightly estrogen-dominant monophasic low-dose oral contraceptive (OC) Diane-35 (Schering AG, Berlin, Germany) (35 micrograms ethinyl estradiol [EE2] + 2 mg ... [more ▼]

OBJECTIVE: To study the effects of the slightly estrogen-dominant monophasic low-dose oral contraceptive (OC) Diane-35 (Schering AG, Berlin, Germany) (35 micrograms ethinyl estradiol [EE2] + 2 mg cyproterone acetate, a 17 alpha-hydroxyprogesterone derivative [17-OHP]) on glucose and insulin metabolism. DESIGN: Seven healthy young women were investigated by using the euglycemic hyperinsulinemic glucose clamp technique (insulin delivery rate = 100 mU/kg per hour for 120 minutes). This test was performed, after an overnight fast, during the last 7 days of a spontaneous cycle and within the last 5 days of pill intake during the sixth and twelfth cycle of a continuous treatment with Diane-35 in each subject. RESULTS: The three indexes measuring the insulin-induced glucose disposal during the clamp (glucose infusion rate, glucose metabolic clearance rate, and glucose infusion rate divided by plasma insulin plateau levels) were not significantly affected by Diane-35. In contrast, the metabolic clearance rate of the exogenous insulin infused during the clamp tended to be slightly increased with Diane-35 (significant after 6 but not after 12 cycles). CONCLUSION: These results suggest that a 1-year treatment with the OC Diane-35, which contains EE2 + a 17-OHP rather than a 19-nortestosterone derivative as the progestogen compound, does not significantly alter peripheral (presumably muscular) insulin sensitivity but slightly increases insulin (presumably hepatic) clearance. [less ▲]

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See detailTotal intravenous anesthesia in South-African genetic porphyria (variegate porphyria)
Bichel, Th; Joris, Jean ULg; Jacquet, N. et al

in Acta Anaesthesiologica Belgica (1993), 44(1), 25-29

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See detailThe Transcriptional Regulation of the Growth Hormone Gene Is Conserved in Vertebrate Evolution
Argenton, F.; Vianello, S.; Bernardini, S. et al

in Biochemical and Biophysical Research Communications (1993), 192(3), 1360-1366

Growth hormone (GH) gene expression in mammals is regulated by the interaction of the transcription factor Pit-1 with two binding sites within the proximal promoter. Four sequences, homologous to the ... [more ▼]

Growth hormone (GH) gene expression in mammals is regulated by the interaction of the transcription factor Pit-1 with two binding sites within the proximal promoter. Four sequences, homologous to the mammalian Pit-1 motif occur in the rainbow trout (Oncorhynchus mykiss) GHII (rtGH) gene promoter, two of which partly overlap. The three regions containing these putative Pit-1 binding sequences were protected from deoxyribonuclease I digestion by nuclear extracts of GC cells, a rat pituitary tumor cell line producing Pit-1. In gel shift assays, nuclear proteins from GC cells and from trout pituitaries were found to interact specifically with one of these protected sites. Transfection experiments showed that the rtGH promoter is transcnptionally active in GC cells, the response being strongly enhanced in the presence of a cAMP analogue. The results demonstrate that rat Pit-1 binds to and activates the rtGH promoter, indicating that the basic mechanisms regulating GH gene transcription have been conserved between fish and mammals. [less ▲]

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See detailFructose utilization during exercise in men: rapid conversion of ingested fructose to circulating glucose.
Jandrain, Bernard ULg; Pallikarakis, N.; Normand, S. et al

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1993), 74(5), 2146-54

The aim of the present study was to compare the metabolic fate of repeated doses of fructose or glucose ingested every 30 min during long-duration moderate-intensity exercise in men. Healthy volunteers ... [more ▼]

The aim of the present study was to compare the metabolic fate of repeated doses of fructose or glucose ingested every 30 min during long-duration moderate-intensity exercise in men. Healthy volunteers exercised for 3 h on a treadmill at 45% of their maximal oxygen consumption rate. "Naturally labeled" [13C]glucose or [13C]fructose was given orally at 25-g doses every 30 min (total feeding: 150 g; n = 6 in each group). Substrate utilization was evaluated by indirect calorimetry, and exogenous sugar oxidation was measured by isotope ratio mass spectrometry on expired CO2. Results were corrected for baseline drift in 13C/12C ratio in expired air due to exercise alone. Fructose conversion to plasma glucose was measured combining gas chromatography and isotope ratio mass spectrometry. Most of the ingested glucose was oxidized: 81 +/- 4 vs. 57 +/- 2 g/3 h for fructose (2P < 0.005). Exogenous glucose covered 20.8 +/- 1.4% of the total energy need (+/- 6.7 MJ) compared with 14.0 +/- 0.6% for fructose (2P < 0.005). The contribution of total carbohydrates was significantly higher and that of lipids significantly lower with glucose than with fructose. The blood glucose response was similar in both protocols. From 90 to 180 min, 55-60% of circulating glucose was derived from ingested fructose. In conclusion, when ingested repeatedly during moderate-intensity prolonged exercise, fructose is metabolically less available than glucose, despite a high rate of conversion to circulating glucose. [less ▲]

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See detailFollicular dendritic cells: isolation procedures, short and long term cultures.
Heinen, Ernst ULg; Tsunoda, R.; Marcoty, C. et al

in Advances in Experimental Medicine and Biology (1993), 329

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See detailEffects of Capsaicin on the Endothelial Permeability in Isolated and Perfused Rabbit Lungs
Delaunois, Annie ULg; Gustin, Pascal ULg; Ansay, Michel ULg

in Fundamental & Clinical Pharmacology (1993), 7(2), 81-91

Changes in pulmonary endothelial permeability and in microvascular hemodynamics in response to capsaicin (10(-4) M) were investigated in isolated, perfused rabbit lungs. Blood-free perfusate was ... [more ▼]

Changes in pulmonary endothelial permeability and in microvascular hemodynamics in response to capsaicin (10(-4) M) were investigated in isolated, perfused rabbit lungs. Blood-free perfusate was recirculated through ventilated lungs in an isogravimetric state, under zone III conditions with a constant flow. Using the occlusions method, the total pressure gradient between the arterial and the venous levels (delta Pt) was partitioned into four components: arterial (delta Pa), pre-(delta Pa') and post-(delta Pv') capillary, and venous (delta Pv). The capillary filtration coefficient (Kf,c) was evaluated by measuring the amount of fluid filtering through the endothelium when arterial and venous pressures were suddenly increased. Capsaicin caused no changes in the vascular pressures at any level of the pulmonary circulation but induced a significant 3-fold increase in the Kf,c (P < 0.05). This reaction was accompanied by pulmonary oedema. The mechanisms involved in the permeability changes were investigated by testing the capacity of different drugs to block the response to capsaicin. Clonidine (10(-7) M to 10(-5) M), morphine (10(-6) M), aspirin (10(-3) M), ketanserin (10(-8) M) and (+/)- CP 96,345 (10(-6) M), an antagonist of neurokinin NK1 receptor, completely prevented the effects of capsaicin on the Kf,c. In contrast, terfenadine (10(-7)) together with cimetidine (10(-5) M) had no protective effect against capsaicin. It was concluded that capsaicin-induced pulmonary oedema was due to an increase in the capillary filtration coefficient and not to hemodynamic changes. This alteration in the endothelium permeability is mediated by the release of endogenous peptides from C-fibers upon the action of capsaicin and subsequent activation of NK1 receptors, probably by substance P. Moreover, 5-hydroxytryptamine receptors and arachidonic acid derivates are also involved in this reaction [less ▲]

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See detailMechanism of action of DD-peptidases: role of asparagine-161 in the Streptomyces R61 DD-peptidase.
Wilkin, J M; Jamin, M; Joris, Bernard ULg et al

in Biochemical Journal (1993), 293 ( Pt 1)

The role of residue Asn-161 in the interaction between the Streptomyces R61 DD-peptidase and various substrates or beta-lactam inactivators was probed by site-directed mutagenesis. The residue was ... [more ▼]

The role of residue Asn-161 in the interaction between the Streptomyces R61 DD-peptidase and various substrates or beta-lactam inactivators was probed by site-directed mutagenesis. The residue was successively replaced by serine and alanine. In the first case, acylation rates were mainly affected with the peptide and ester substrates but not with the thiol-ester substrates and beta-lactams. However, the deacylation rates were decreased 10-30-fold with the substrates yielding benzoylglycyl and benzoylalanyl adducts. The Asn161Ala mutant was more generally affected, although the acylation rates with cefuroxime and cefotaxime remained similar to those observed with the wild-type enzyme. Surprisingly, the deacylation rates of the benzoylglycyl and benzoylalanyl adducts were very close to those observed with the wild-type enzyme. The results also indicate that the interaction with the peptide substrate and the transpeptidation reaction were more sensitive to the mutations than the other reactions studied. The results are discussed and compared with those obtained with the Asn-132 mutants of a class A beta-lactamase. [less ▲]

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See detailQuantitative estimation of chimerism in mice using microsatellite markers
Delhaise, F.; Zhao, X.; Dessy, F. et al

in Molecular Reproduction and Development (1993), 34(2), 127-132

An embryonic stem cell line was established from SV129 mouse blastocysts and used to generate chimeric mice by injection into OF1 blastocysts; 18 out of the 30 resulting offspring appeared chimeric as ... [more ▼]

An embryonic stem cell line was established from SV129 mouse blastocysts and used to generate chimeric mice by injection into OF1 blastocysts; 18 out of the 30 resulting offspring appeared chimeric as judged from their coat color patterns, and 3 of the 13 males proved to be germ-line chimeras as they transmitted the SV129 agouti phenotype to all or part of their offspring. The degree of chimerism of these males was evaluated for different tissues using polymorphic microsatellite markers amplified by the polymerase chain reaction. It was shown that these new markers can be effectively used to quantitatively estimate levels of chimerism. The CKMM (creatine kinase, muscle) microsatellite system was used to distinguish the SV129 from the OF1 genotype. In all performed tests, the correlation between DNA ratio and signal ratio, expressed as a base 10 logarithm, was shown to exceed or equal 0.98 for known DNA ratios (SV129/OF1) ranging from 1/99 to 99/1. Linear calibration methods were used to predict the % SV129 DNA of a test sample based on the obtained signal ratio. The accuracy of the prediction was evaluated by performing repeated measurements. Differences among three repeated estimates ranged from 2 to 17% for a given sample. Microsatellite systems should be very useful to monitor chimerism involving strains that can not be discerned with coat color or biochemical markers. This will be particularly important when ES methodology becomes available in species other than mice. [less ▲]

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See detailComputed subsidence of the central area of Shanghai
Dassargues, Alain ULg; Radu, Jean-Pol ULg; Charlier, Robert ULg et al

in Bulletin of Engineering Geology & the Environment (1993), 47

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See detailLinks between Egyptian and Greek Medicine
Marganne, Marie-Hélène ULg

in Forum (1993), 3(5), 35-43

Given the present state of our knowledge, the question about the links between Egyptian and Greek medicine is far from being resolved. Some convergences can in fact be detected, but when you study them ... [more ▼]

Given the present state of our knowledge, the question about the links between Egyptian and Greek medicine is far from being resolved. Some convergences can in fact be detected, but when you study them further, you will find that they reveal a loan, or a simple coincidence, or else a false interpretation of the sources. At the end of the sixth century BC, Pharaonic medicine was outclassed and influenced little by little by Greek medicine. Lastly, the Coptic medical treatises, composed in Egyptian language, but written in Greek characters, combine some Greek and finally Arabic borrowings. [less ▲]

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See detailImportance of Weight Loss and Sodium Restriction in the Treatment of Mild and Moderate Essential Hypertension
Krzesinski, Jean-Marie ULg; Janssens, Marion; Vanderspeeten, Francine et al

in Acta Clinica Belgica (1993), 48(4), 234-245

The effectiveness of non pharmacological treatment of chronic arterial hypertension has been evaluated in 116 treated or not primary hypertensive out-patients. Those receiving diuretics were however ... [more ▼]

The effectiveness of non pharmacological treatment of chronic arterial hypertension has been evaluated in 116 treated or not primary hypertensive out-patients. Those receiving diuretics were however excluded. This population was requested to follow for 3 months a modification of their usual diet characterized by salt restriction combined with energy intake restriction when the patients were above their ideal body weight. Only 62 patients (53%) completed the study. However, this approach was effective by decreasing blood pressure and total cholesterol. The weight loss appears the most effective way to decrease blood pressure in untreated patients, but needs 3 months to be significant. In drug-treated patients, the sodium restriction significantly influences the blood pressure level, already after 1 month. However, salt sensitivity has been noted, especially in the most severe forms of the hypertensive disease. The combination of both modifications (weight loss and sodium restriction) does not appear to be more effective than each separate dietary measure. [less ▲]

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See detailStrutture asindetiche nella poesia italiana delle origini, Firenze.
Moreno, Paola ULg

in Revue Belge de Philologie et d'Histoire (1993)

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See detailDe la perversité des comptes rendus
Winand, Jean ULg

in Göttinger Miszellen (1993), 134

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See detailPHOTOREDUCTION OF PROTOCHLOROPHYLLIDE TO CHLOROPHYLLIDE IN 2-D-OLD DARK-GROWN BEAN (PHASEOLUS-VULGARIS CV COMMODORE) LEAVES - COMPARISON WITH 10-D-OLD DARK-GROWN (ETIOLATED) LEAVES
SCHOEFS, B.; Franck, Fabrice ULg

in Journal of Experimental Botany (1993), 44(263), 1053-1057

Two-d-old leaves which do not contain prolamellar bodies synthesize active protochlorophyllide in darkness. When protochlorophyllide is photoreduced by one intense white flash, a main chlorophyllide ... [more ▼]

Two-d-old leaves which do not contain prolamellar bodies synthesize active protochlorophyllide in darkness. When protochlorophyllide is photoreduced by one intense white flash, a main chlorophyllide species emitting at 690 nm is formed. After the photoreduction, the emission maximum is shifted to 675 nm within 5 s. This result suggests that in young leaves, chlorophyllide formed after one flash is quickly released from the active site of NADPH: protochlorophyllide oxidoreductase. This interpretation is strenghtened by time-resolved fluorescence measurements at room temperature, showing that 675 nm emitting chlorophyllide does not transfer excitation energy to the 696 nm emitting chlorophyllide which is formed in very low amount. In 10-d-old bean leaves, the 690 nm chlorophyllide emitting species formed after one short flash undergoes the well-known rapid and Shibata spectral shifts. The 675 nm emitting chlorophyllide appears only as a shoulder. At both ages, the fluorescence intensity of the active protochlorophyllide strongly decreases during and after photoreduction, suggesting rapid modifications in the close environment of the pigment. [less ▲]

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See detailAnalyse de la viande de poulet par spectroscopie infrarouge proche.
Sindic, Marianne ULg; Chevalier, Olivier; Dardenne, Pierre et al

in Viandes et Produits Carnés (1993), 14(4),

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See detailLes auteurs latins et les langues étrangères
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (1993), 52

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See detailEarly prediction of response to recombinant human erythropoietin in patients with the anemia of renal failure by serum transferrin receptor and fibrinogen.
Beguin, Yves ULg; Loo, Martine; R'Zik, Samir ULg et al

in Blood (1993), 82(7), 2010-6

Recombinant human erythropoietin (rHuEpo) has been shown to be effective in correcting the anemia of chronic renal failure, but the dose needed may be variable. The reason for this variation is not known ... [more ▼]

Recombinant human erythropoietin (rHuEpo) has been shown to be effective in correcting the anemia of chronic renal failure, but the dose needed may be variable. The reason for this variation is not known, but several factors could be involved, such as iron deficiency, inflammation, aluminum intoxication, hyperparathyroidism, blood losses, or marrow dysfunction. Treatment with rHuEpo was given intravenously thrice weekly after hemodialysis to 64 consecutive unselected patients with the anemia of chronic renal failure. The starting dose was 50 U/kg/dose, which was increased to 75 and 100 U/kg/dose if no response was observed after 1 and 2 months of treatment. After a minimum follow-up of 6 months, response was evaluated as early (hematocrit [Hct] > or = 30% before 3 months) or late (Hct > or = 30% after 3 months) response, or failure (target Hct not attained). We examined the value of various laboratory parameters (baseline values and early changes) as predictors of response to rHuEpo. The best prediction by pretreatment parameters only was obtained with baseline serum transferrin receptor (TfR) (< or > or = 3,500 ng/mL) and fibrinogen (< or > or = 4 g/L): 100% response rate when both parameters were low, versus only 29% when they were both high, and versus 67% when one was low and the other high. When the 2-week TfR increment was greater than 20%, the response rate was 96%. When TfR increment was less than 20%, the response rate was 100% when baseline TfR and fibrinogen were low, 12% when fibrinogen was elevated, and 62% when fibrinogen was low but baseline TfR high. The predictive value of baseline TfR and fibrinogen and of the 2-week increment of TfR was confirmed by life table analysis and stepwise discriminant analysis. Major reasons for failure or late response were identified and included subclinical inflammation, iron deficiency, functional iron deficiency, marrow disorders, hemolysis, bleeding, and low Epo dose. We conclude that response to rHuEpo can be predicted early by pretreatment fibrinogen and TfR, together with early changes of TfR levels. These prognostic factors illustrate the importance of the early erythropoietic response, subclinical inflammation, and functional iron deficiency. Early recognition of a low probability of response in a given patient could help identify and correct specific causes of treatment failure to hasten clinical improvement and avoid prolonged ineffective use of an expensive medication. [less ▲]

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See detailMuscles rotateurs d'épaule et isocinétisme
Croisier, Jean-Louis ULg; Mommer, R.; Crielaard, Jean-Michel ULg

in Médecine et Hygiène (1993), 51

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See detailHypofractionation in retinoblastoma: an increased risk of retinopathy.
Coucke, Philippe ULg; Mirimanoff, R-O; Schmid, C et al

in Radiotherapy & Oncology (1993), 28

Forty-four eyes in 38 children were treated between 1963 and 1991 by external radiotherapy for retinoblastoma. Treatment modalities varied widely during this period; in addition to radiotherapy there was ... [more ▼]

Forty-four eyes in 38 children were treated between 1963 and 1991 by external radiotherapy for retinoblastoma. Treatment modalities varied widely during this period; in addition to radiotherapy there was chemotherapy (16/44), photocoagulation (14/44), and laser therapy or cryotherapy (14/44). Treatment technique and dose fractionation also varied widely; lateral beam technique (39/44) versus anterior or anterior/lateral beam; doses per fraction ranged from 1 to 4.5 Gy, total doses from 30 to 61.5 Gy, and overall times from 22 to 49 days. Patients were followed at 3-month intervals, and actuarial survival at 10 years was 88%, with 62% local control. Ten eyes showed clinical evidence of retinopathy. A multivariate analysis of factors associated with increased risk of retinopathy was carried out using the Cox proportional hazards model and the mixture model of Farewell. The estimated latent time was 17 months (95% confidence interval, 14-20 months). The only factors found to be significantly associated with retinopathy were total dose multiplied by dose per fraction, or total dose normalized to the equivalent total dose in 2-Gy fractions as estimated from the LQ model, and these gave equivalent descriptions. There were trends (not significant) for increased risk of retinopathy when treatments included chemotherapy or photocoagulation, and for decreased risk (also not significant) when cryotherapy was used in conjunction with radiotherapy. No significance could be attached to any of the following: number of sites per eye, Reese-Ellsworth stage, and family history. We conclude that hypofractionation carries a significant risk for retinopathy in the treatment of retinoblastoma. [less ▲]

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See detailLa régionalisation du droit pénal international
Flore, Daniel ULg; Thomas, F.

in Revue de Droit Pénal et de Criminologie (1993)

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See detailStructure of the apolipoprotein A-IV/lipid discoidal complexes: an attenuated total reflection polarized Fourier transform infrared spectroscopy study.
Lins, Laurence ULg; Brasseur, Robert ULg; Rosseneu, M. et al

in Biochimica et Biophysica Acta (1993), 1149(2), 267-77

Discoidal lipid particles were prepared from a reaction mixture containing apo A-IV and dimyristoylphosphatidylcholine (DMPC) or dipalmitoylphosphatidylcholine (DPPC) in the molar ratio of 185:1 (lipid ... [more ▼]

Discoidal lipid particles were prepared from a reaction mixture containing apo A-IV and dimyristoylphosphatidylcholine (DMPC) or dipalmitoylphosphatidylcholine (DPPC) in the molar ratio of 185:1 (lipid/protein). The complexes were isolated by gel filtration and characterized in terms of composition and size. Infrared attenuated total reflection spectroscopy was used to estimate the secondary structure of apolipoprotein A-IV and the orientation of its amphipathic alpha-helices with respect to the lipid hydrocarbon chains. In addition, infrared spectra were analyzed in terms of the conformation and organization of different regions of the lipid molecules in the particles. This approach has been applied successfully to reconstituted HDL particles prepared from a reaction mixture containing DPPC and apo A-I in the molar ratio of 150:1 (Wald, J.H., Goormaghtigh, E., De Meutter, J., Ruysschaert, J.M. and Jonas, A. (1990) J. Biol. Chem. 265, 20044-20050). Apo A-IV helicity increased for the protein bound to DMPC or DPPC but the increase was more pronounced for the apo A-IV/DMPC particles. In both complexes, the alpha helical amphipathic segments of the protein were parallel to the lipid acyl chains and no significant modification of the overall organization of the lipid molecules in the lipid bilayer was observed. The presence of apo A-IV seems only to affect the conformation of the lipid hydrocarbon chains in close contact with the protein in the discoidal particles. [less ▲]

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See detailLes articles 19 et 93 de la loi relative au crédit à la consommation, obs sous civ. Dinant, 28 juin 1989 et Liège, 26 juin 1992
Biquet, Christine ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1993)

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See detailNut van ambulante bloeddrukmeting bij arteriële hypertensie
Saint-Remy, Annie ULg; Dubois, Bernard ULg; Krzesinski, Jean-Marie ULg et al

in Journal de Cardiologie [= JDC] = Tijdschrift voor Cardiologie [= TVC] (1993), 1

De frequentie van het 'witte-jassen' syndroom en het belang van dit fenomeen op de bloeddrukbelasting en de variabiliteit van de arteriële bloeddruk over 24 uur werden bij 181 patiënten onderzocht ... [more ▼]

De frequentie van het 'witte-jassen' syndroom en het belang van dit fenomeen op de bloeddrukbelasting en de variabiliteit van de arteriële bloeddruk over 24 uur werden bij 181 patiënten onderzocht gedurende een 24 uur durende ambulante bloeddrukmeting. Ondanks een goede correlatie tussen de klinische meting van de arteriële bloeddruk en de gemiddelde bloeddruk overdag of gedurende 24 uur, is er toch een tegenstrijdigheid tussen de .bloeddrukwaarden die met beide methoden worden gemeten (de klinische bloeddruk is hoger dan de ambulant gemeten bloeddruk, des te meer naarmate de klinische bloeddruk hoger is). Bij de beoordeling van de werkzaamheid van antihypertensiva blijkt uit het beloop van de bloeddruk dat een derde van de behandelde patiënten normale bloeddrukwaarden heeft, terwijl bij twee derden van de patiënten de gemiddelde bloeddruk overdag en gedurende 24 uur duidelijk hoger is dan per definitie is toegestaan. Dit onderzoek toont ook aan dat de ambulant gemeten bloeddrukwaarden (vooral de systolische bloeddruk) een beter voorspellend vermogen voor linker-ventrikelhypertrofie hebben dan de klinisch gemeten bloeddrukwaarden. Deze waarnemingen bevestigen het belang van deze niet-invasieve techniek van meting van de gemiddelde bloeddruk, zowel om het 'witte-jassen' effect te objectiveren en aldus de diagnose arteriële hypertensie te preciseren, als om na te gaan of de bloeddruk met antihypertensiva goed is ingesteld. [less ▲]

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See detailWanze/Huccorgne: Station de l'Hermitage
Noiret, Pierre ULg

in Chronique de l'Archéologie wallonne (1993), 1

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See detailThe Implications of European Union for the Performance of Public Enterprises
Gathon, Henry-Jean ULg; Pestieau, Pierre ULg

in Administration : Journal of the Institute of Public Administration of Ireland (1993), 41(Summer), 149-165

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See detailSYNCYTIOTROPHOBLASTIC LOCALIZATION OF THE HUMAN GROWTH-HORMONE VARIANT MESSENGER-RNA IN THE PLACENTA
Scippo, Marie-Louise ULg; Frankenne, Francis ULg; HOOGHEPETERS, ELisabeth et al

in Molecular & Cellular Endocrinology (1993), 92(2), 7-13

The hGH/hCS genes, clustered on chromosome 17 in the 5' to 3' order GH-N, CS-L, CS-A, GH-V and CS-B, show a high degree of sequence identity. The expression product of the GH-V gene is the placental ... [more ▼]

The hGH/hCS genes, clustered on chromosome 17 in the 5' to 3' order GH-N, CS-L, CS-A, GH-V and CS-B, show a high degree of sequence identity. The expression product of the GH-V gene is the placental growth hormone, which replaces pituitary GH in maternal blood throughout pregnancy. By means of mRNA competitive hybridization using P-32-labelled and unlabelled 30 bases long oligonucleotides, we first optimized specific hybridization conditions. In situ hybridization was then performed to locate the GH-V mRNA encoding placental growth hormone. The hGH-V gene appears expressed in the placental syncytiotrophoblast. Unlike the CS-A and CS-B genes (both encoding hPL) which are expressed uniformly in the syncytiotrophoblast, the GH-V mRNA is located in a few syncytiotrophoblast cells only. [less ▲]

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See detailLa collaboration entre les CPAS et autres institutions d'Aide Sociale
Gavray, Claire ULg; Huvelle, P.

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1993), 1-2

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See detailLaparoscopy, urology, and gynaecology
Joris, Jean ULg

in Current Opinion in Anaesthesiology (1993), 6

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See detailEffect of the vector-axial-vector coupling on the vector-meson modes
Jaminon, Martine ULg; Mendez Galain, Ramon

in Nuclear Physics A (1993), 564

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See detailFractionnement du froment d'hiver : influences variétale et phytotechnique.
Sindic, Marianne ULg; Chevalier, Olivier; Duculot, Jacqueline et al

in Industries des Céréales (1993), (82),

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See detailThe central role of the thymus in the education of T cells to neuroendocrine self principles
Geenen, Vincent ULg; Martens, Henri ULg; Cormann-Goffin, Nadine et al

in Archives Internationales de Physiologie et de Biochimie (1993), 101

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See detailViolences des jeunes : à l'école et ailleurs ?
Born, Michel ULg; Gavray, Claire ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1993), 6

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See detailIntercultural Education in French-speaking Belgium : an overview of ideology, legislation and practice
Martiniello, Marco ULg; Manço, Altay

in European Journal of Intercultural Education (1993), 4(2), 19-28

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See detailDe lugebere droom van W.F. Hermans. Hermans'mythologie in het licht van A. Schopenhauer
Yans, Baudoin ULg

in Spiegel der Letteren (1993), (1), 47-61

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See detailRole du systeme dopaminergique dans la depression: correlats cliniques du test a l'apomorphine.
Pitchot, William ULg; Gonzalez Moreno, Antonio; Hansenne, Michel ULg et al

in Acta Psychiatrica Belgica (1993), 93 Spec No

Disturbances in dopaminergic neurotransmission seem to play an important role in biochemical mechanisms involved in depressive disorders. The study of the growth hormone (GH) response to apomorphine, a ... [more ▼]

Disturbances in dopaminergic neurotransmission seem to play an important role in biochemical mechanisms involved in depressive disorders. The study of the growth hormone (GH) response to apomorphine, a dopaminergic agonist, provides an indirect index of dopaminergic neurotransmission at the postsynaptic level. In the present study, we assessed the role of the dopaminergic system in some psychopathological dimensions in depression: personality dimensions, suicidal behavior, psychomotor disturbances and dichotomy unipolar/bipolar. Our studies included major depressed inpatients matched for gender, age and, in the case of women, menopausal status. Our results show that dopaminergic disturbances are related to social introversion and anxiety according to dopaminergic hypothesis of schizophrenic disorders and dopaminergic hyperactivity hypothesis of anxiety disorders. A blunted GH response to apomorphine could be considered as a biological marker of suicidal behavior. Moreover motor retardation appeared to be in relationship with dopaminergic disturbances. Finally, the dopaminergic system did not appear to play a significant role in the dichotomy unipolar/bipolar. The results show the interest of the apomorphine test in the assessment of the relationship between biochemical disturbances and clinical correlates. [less ▲]

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See detailSomatosensory potentials in dogs suffering naturally-acquired thoraco-lumbar spinal cord disease
Poncelet, Luc; Michaux, Ch.; Balligand, Marc ULg

in American Journal of Veterinary Research (1993)

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See detailCloning of a human GHF-1/Pit-1 cDNA variant
Pernasetti, Flavia; Wera, Stefaan; Belayew, Alexandra et al

in Nucleic Acids Research (1993), 21(15), 3584

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See detailcr de J. Cerny, Papyrus hiératiques de Deir el-Médineh, t. II
Winand, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1993), 68

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See detailLa saisie électronique des données en forêt : réalités et perspectives
Rondeux, Jacques ULg

in Revue Forestière Française (1993), 45(n° sp), 20-26

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See detailL'agriculteur et les aides directes aux revenus
Lebailly, Philippe ULg

in Nouvelles des Sciences et des Technologies (1993), 11(2), 171-176

Le but de cet article est de présenter les différents volets de la politique agricole qui permettent un soutien aux agriculteurs par le biais d'aides directes aux revenus. Après avoir présenté le ... [more ▼]

Le but de cet article est de présenter les différents volets de la politique agricole qui permettent un soutien aux agriculteurs par le biais d'aides directes aux revenus. Après avoir présenté le dispositif mis en place en Belgique pour les régions agricoles défavorisées, l'auteur s'attarde sur les aspects de la réforme de la PAC qui introduisent les paiements directs. Les changements les plus importants concernant les cultures arables et le fonctionnement du système sont présentés de manière détaillée. Enfin, l'auteur présente les mesures d'accompagnement de la réforme de la politique des marchés et des prix. [less ▲]

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See detailMesures quantitatives de l'erythropoiese. Le recepteur soluble de la transferrine.
Beguin, Yves ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1993), 148(1-2), 100-4105-7

Iron transport in plasma is carried out by transferrin, which donates iron to cells through its interaction with a specific membrane receptor. The soluble form of the transferrin receptor has been ... [more ▼]

Iron transport in plasma is carried out by transferrin, which donates iron to cells through its interaction with a specific membrane receptor. The soluble form of the transferrin receptor has been identified in plasma. Dosage of the soluble receptor represents a simple, reliable, quantitative assay of erythropoiesis, which should replace the standard ferrokinetic measurement. Using this dosage, it is now possible to investigate the pathophysiology of anemia in many conditions, and to analyze the erythropoietic response to treatment with recombinant erythropoietin. [less ▲]

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See detailContribution à l'étude des effets de l'exposition à des champs magnétiques 50 Hz sur certains paramètres neuropsychologiques et neuroendocriniens
Crasson, Marion ULg; Timsit-Berthier, Martine; Legros, Jean-Jacques ULg

in Psychologie Médicale (1993), 25(13), 1341-1346

Depuis une trentaine d'années, l'exposition des populations industrialisées aux champs électromagnétiques 50/60 Hz n'a cessé de susciter des polémiques concernant ses éventuels effets nocifs. Cette étude ... [more ▼]

Depuis une trentaine d'années, l'exposition des populations industrialisées aux champs électromagnétiques 50/60 Hz n'a cessé de susciter des polémiques concernant ses éventuels effets nocifs. Cette étude préliminaire a été réalisée avec un appareillage original, qui génère des champs magnétiques comparables à ceux rencontrés dans la vie quotidienne. Deux groupes de 10 volontaires en bonne santé ont participé à cette recherche, le premier réellement exposé à un champ d'induction magnétique de 142 microtesla, 50 Hz, pendant une demi-heure, le deuxième exposé de manière simulée. Nos résultats montrent que le champ magnétique n'engendre aucun effet perceptible mais qu'il provoque une légère modification de certains paramètres psychologiques (humeur, attention visuelle). [less ▲]

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See detailMesurer les compétences en lecture: Apports et limites d'une enquête internationale
Lafontaine, Dominique ULg

in Lettre de la DFLM (La) (1993), 12

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See detailEscherichia coli productrices de la toxine cytotoxique nécrosante de type 1 (CNF1) isolées à partir de processus pathologiques chez des chats et des chiens
Pohl, P.; Mainil, Jacques ULg; Devriese, L. et al

in Annales de Médecine Vétérinaire (1993), 137

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See detailInterface entre médecin de famille, référent social et psychiatrie: un hôpital de jour
Triffaux, Jean-Marc ULg; Halkin, Stéphane ULg; Bertrand, Jean ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1993)

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See detailLa voie navigable Anvers-Dusseldorf pour une liaison Meuse-Rhine
Rigo, Philippe ULg

in Bulletin de l’Association Internationale Permanente des Congrès de Navigation [Bulletin de l'AIPCN] (1993)

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See detailLes formations frasniennes du Massif de Philippeville
Boulvain, Frédéric ULg; Coen, M.; Coen-Aubert, M. et al

in Professional Paper Belgian Geological Survey (1993), 259

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See detailLa société québécoise après 30 ans de changements, sous la direction de Fernand Dumont (compte rendu)
Fournier, Bernard ULg

in Revue canadienne de science politique (1993), 26(2), 392-394

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See detailDensitometric Determination of Salicin in Willow Stem Bark
Poukens-Renwart, Pascale; Tits, Monique ULg; Angenot, Luc ULg

in Journal of Planar Chromatography (1993), 6(november-december), 434-437

Most of the salicin present in willow stem bark occurs as labile glycosides (e.g. salicin, salicortin, 2-O'-acetylsalicortin, 3-O'-acetylsalicortin, tremulacin and fragilin). On alkaline hydrolysis, these ... [more ▼]

Most of the salicin present in willow stem bark occurs as labile glycosides (e.g. salicin, salicortin, 2-O'-acetylsalicortin, 3-O'-acetylsalicortin, tremulacin and fragilin). On alkaline hydrolysis, these acylated derivatives decompose to salicin; in this way, the total amount of salicin can be determined. A HPTLC method has been developed for the quantitative determination of salicin in stem bark before and after alkaline hydrolysis. The mobile phase used for the separation is a modification of one described in the literature. a double or triple migration is necessary to separate salicin from other components of the extract. The results have been compared with those obtained after bidimensional chromatography using two phases described for the quantitative evaluation of salicin. to check that separation was complete, the spectrum of salicin obtained from willow extracts was superimposed on that of a salicin standard.Quantification was performed at lambda = 270nm, the wavelenght of maximum absorption in the IV spectrum of salicin. [less ▲]

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See detailCrystallization of a genetically engineered water-soluble primary penicillin target enzyme. The high molecular mass PBP2x of Streptococcus pneumoniae.
Charlier, Paulette ULg; Buisson, G.; Dideberg, O. et al

in Journal of Molecular Biology (1993), 232(3), 1007-9

A genetically engineered water-soluble derivative of PBP2x of Streptococcus pneumoniae has been produced, purified and crystallized in a form suitable for X-ray diffraction analysis. The best crystals ... [more ▼]

A genetically engineered water-soluble derivative of PBP2x of Streptococcus pneumoniae has been produced, purified and crystallized in a form suitable for X-ray diffraction analysis. The best crystals have been grown at 15 degrees C, from solutions containing 8% polyethylene glycol 10,000 at pH values ranging from 3.9 to 6.0. These crystals diffract to a resolution of 3.5 A and have a space group P6(1)22 (or enantiomorph) with unit cell dimensions of a = b = 162.2 A, c = 171.8 A, alpha = beta = 90 degrees, gamma = 120 degrees. The molecular mass and cell dimensions suggest that there is one molecule of enzyme per asymmetric unit. The breakdown of a chromogenic cephalosporin derivative diffused into a crystal reveals clearly that the enzyme is active in the crystalline state. [less ▲]

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See detailP. Colon. Inv. 4781 verso: vente d'une esclave
Straus, Jean ULg

in Zeitschrift für Papyrologie und Epigraphik (1993), 98

Edition du contrat de vente d'une esclave. Papyrus grec d'Egypte. Ptolémaïs Euergétis, 3 décmebre 65

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See detailL'histoire de Méléagre : plaidoyer pour une analyse de l'ensemble du mythe
Renaud, Jean-Michel ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (1993), 6

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See detailMonoclonal-Antibodies To Bovine Growth-Hormone Potentiate Hormonal Activity In-Vivo By Enhancing Growth-Hormone Binding To Hepatic Somatogenic Receptors
Massart, Serge; Maiter, D.; Portetelle, Daniel ULg et al

in Journal of Endocrinology (1993), 139(3),

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See detailAérosolthérapie chez le cheval : 3. Etude clinique
Lekeux, Pierre ULg; Genicot, Bruno; Votion, Dominique ULg et al

in Pratique Vétérinaire Equine (1993), 25(4), 245-248

This review analyzes the advantages, disadvantages, limites and clinical applications of aerosoltherapy in equine medicine

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See detailEvolution de la situation des mammifères sauvages en Région wallonne au cours de décennie 1983-1992
Libois, Roland ULg

in Cahiers d'Ethologie (1993), 13(1), 77-92

During the last ten years, the evolution of the status of the mammal fauna of Wallony (southern part of Belgium) can be characterized by four main trends: i- enforcement of a better legal protection ii ... [more ▼]

During the last ten years, the evolution of the status of the mammal fauna of Wallony (southern part of Belgium) can be characterized by four main trends: i- enforcement of a better legal protection ii- arrival of at least four new species: coypu, raccoon, raccon-dog and American mink iii- restoration of badger numbers following the efficient control of rabies iv- increase of anthropophilic or game species (stone marten, ungulates). Unfortunately, the most threathened species (otter, horseshoe bats, barbastella) did not recover. [less ▲]

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See detailRespiratory response to abdominal and rib cage muscle paralysis in dogs.
Brichant, Jean-François ULg; Gorini, Massimo; De Troyer, André

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1993), 74(5), 2309-17

To assess the respiratory response to abdominal and rib cage muscle paralysis, we measured tidal volume, esophageal and gastric pressures, arterial blood gases, and the electromyogram (EMG) of the ... [more ▼]

To assess the respiratory response to abdominal and rib cage muscle paralysis, we measured tidal volume, esophageal and gastric pressures, arterial blood gases, and the electromyogram (EMG) of the diaphragm during progressive epidural anesthesia (lidocaine 2%) in 35 supine anesthetized dogs. The EMG activity of the diaphragm was measured with fine-wire electrodes; the abdominal cavity was thus left intact. Paralysis of the abdominal muscles alone did not produce any alterations. In contrast, when all rib cage muscles were also paralyzed, there were substantial increases in the peak height and the rate of rise of diaphragmatic EMG activity that were associated with a decrease in tidal volume and an increase in arterial PCO2 (PaCO2); swings in transdiaphragmatic pressure, however, were unchanged. The increased diaphragmatic activation due to rib cage muscle paralysis persisted after bilateral cervical vagotomy and was well explained by the increased PaCO2. These observations indicate that in the dog 1) the rib cage muscles contribute significantly to tidal volume, and their paralysis causes, through the increased hypercapnic drive, a compensatory increase in diaphragmatic activation; and 2) the rib cage inspiratory muscles enhance the diaphragm's ability to generate pressure during breathing. [less ▲]

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See detailStructure of triosephosphate isomerase from Escherichia coli determined at 2.6 A resolution
Noble, M. E.; Zeelen, J. P.; Wierenga, R. K. et al

in Acta Crystallographica Section D-Biological Crystallography (1993), 49(Pt 4), 403-17

The structure of triosephosphate isomerase (TIM) from the organism Escherichia coli has been determined at a resolution of 2.6 A. The structure was solved by the molecular replacement method, first at 2.8 ... [more ▼]

The structure of triosephosphate isomerase (TIM) from the organism Escherichia coli has been determined at a resolution of 2.6 A. The structure was solved by the molecular replacement method, first at 2.8 A resolution with a crystal grown by the technique of hanging-drop crystallization from a mother liquor containing the transition-state analogue 2-phosphoglycolate (2PG). As a search model in the molecular replacement calculations, the refined structure of TIM from Trypanosoma brucei, which has a sequence identity of 46% compared to the enzyme from E. coli, was used. An E. coli TIM crystal grown in the absence of 2PG, diffracting to 2.6 A resolution, was later obtained by application of the technique of macro-seeding using a seed crystal grown from a mother liquor without 2PG. The final 2.6 A model has a crystallographic R factor of 11.9%, and agrees well with standard stereochemical parameters. The structure of E. coli TIM suggests the importance of residues which favour helix initiation for the formation of the TIM fold. In addition, TIM from E. coli shows peculiarities in its dimer interface, and in the packing of core residues within the beta-barrel. [less ▲]

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See detailEchec des élèves, échec de l'école ?
Crahay, Marcel ULg

in Recherche en Education. Théorie & Pratique (1993), 11-12

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See detailC.R. de S. KAY, Subjectivity in Troubadour Poetry
Henrard, Nadine ULg

in Moyen Age (Le) (1993), IC

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See detailLong-Term Photometry of Variables at ESO. II. The Second Data Catalogue (1986-1990).
Sterken, C.; Manfroid, Jean ULg; Anton, K. et al

in European Southern Observatory Scientific Report (1993), 12

Not Available

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See detailLasfe (CIL IV 2319 l) et quelques autres exemples d’usage abusif de l’épigraphie en phonétique historique
Purnelle, Gérald ULg

in Etudes Classiques (Namur, Belgium) (1993), 61

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See detailSequence of a gene encoding a (poly ManA) alginate lyase active on Pseudomonas aeruginosa alginate
Malissard, Martine; Duez, Colette ULg; Guinand, Micheline et al

in FEMS Microbiology Letters (1993), 110(1), 101-106

The recombinant plasmid pAL-A3 bears a (poly ManA) alginate lyase-encoding gene that originates from the marine bacterium ATCC 433367 (Brown et al., Appl. Environ. Microbiol. (1991) 57, 1870-1872). The ... [more ▼]

The recombinant plasmid pAL-A3 bears a (poly ManA) alginate lyase-encoding gene that originates from the marine bacterium ATCC 433367 (Brown et al., Appl. Environ. Microbiol. (1991) 57, 1870-1872). The alginate lyase produced by Escherichia coli TC4 harbouring pAL-A3 was purified to protein homogeneity and the corresponding gene sequenced, giving access to the first known primary structure of an alginate lyase. The 265-amino acid residue alginate lyase showed lytic activity on a Pseudomonas aeruginosa alginate isolated from a cystic fibrosis patient. Unexpectedly, the alginate lyase thus characterized differed from that isolated from the culture medium of the bacterium ATCC 433367 (Romeo and Preston, Biochemistry (1986) 25, 8385-8391). [less ▲]

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See detailRELATIVE IMPORTANCE OF FACTORS CONTROLLING THE LEACHING AND UPTAKE OF INORGANIC-IONS IN THE CANOPY OF A SPRUCE FOREST
Hambuckers, Alain ULg; Remacle, Jean ULg

in Biogeochemistry (1993), 23(2), 99-117

Sequential sampling of precipitation under mature spruce trees and time-series analysis of the data were performed in order to assess, in natural conditions, the relative importance of different factors ... [more ▼]

Sequential sampling of precipitation under mature spruce trees and time-series analysis of the data were performed in order to assess, in natural conditions, the relative importance of different factors that could influence the leaching and uptake of inorganic ions in the canopy. Eleven rain events were analyzed in order to estimate how external factors, rain intensity, H+, and ionic concentration of the incident rain influence the ionic throughfall concentrations and the net throughfall fluxes. The results led to the conclusion that leaching or uptake mostly occur by diffusion. The influence of the open rain acidity was not conclusive; however, it was shown that the tested external factors only controlled a few percent of the variation of the data. By contrast, the autocorrelation of the data always explained a large portion of the variance. lt could result from the gradual changes in the course time of internal factors related to the exchange system including waxes, cuticles, apoplast and xylem sap. These constituents were known to control the exchange at the canopy surface and to be sensitive to the plant physiology and environmental conditions. [less ▲]

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See detailConnection and frame design for economy
Anderson, D.; Colson, A.; Jaspart, Jean-Pierre ULg

in New Steel Construction (1993), 1(N°6), 30-33

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See detailDes inscriptions de sceaux-cylindres diverses provenant d'Acemhöyük
Tunca, Önhan ULg

in Aspects of Art and Iconography: Anatolia and its Neighbors. Studies in Honor of Nimet Özgüç (1993)

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