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See detailTHERMAL-CONDUCTIVITY OF PURE OR IRON-DOPED YBA2CU3O7-DELTA WITH OR WITHOUT AN EXCESS OF CUO
Houssa, M.; Bougrine, Hassan ULg; Ausloos, Marcel ULg et al

in Journal of Physics : Condensed Matter (1994), 6(31), 6305-6316

The thermal conductivities of YBa2(Cu1-xFex)3O7-delta + y% CuO ceramics for 0 < x < 0.03 and 0 < y < 5 have been measured. The thermal conductivities of all samples exhibit a minimum in the vicinity of ... [more ▼]

The thermal conductivities of YBa2(Cu1-xFex)3O7-delta + y% CuO ceramics for 0 < x < 0.03 and 0 < y < 5 have been measured. The thermal conductivities of all samples exhibit a minimum in the vicinity of the critical temperature T(c) and a maximum near T(c)/2. These results are interpreted with the help of an electronic model, i.e. supposing that the main contribution to the thermal conductivity below T(c) is due to electron scattering in the CuO2 planes. Within a simple two-fluid model derived from kinetic theory, taking into account the temperature dependence of the electronic relaxation time and the normal charge carrier concentration, we obtain theoretical curves which reproduce the experimental results quite well. We also take into account the porosity of the samples (in term of an intergrain contribution) to derive the electronic thermal conductivity. The parameter values of the model and the observed minimum are explained in terms of physical properties. In particular, the contribution of superconductivity fluctuations to the thermal conductivity is shown to be negligible with respect to other mechanisms. [less ▲]

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See detailHuman follicular dendritic cells in vitro
Tsunoda, R.; Heinen, Ernst ULg; Imai, Y. et al

in Dendritic Cells (1994), 4

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See detailEffect of dopamine and baclofen on N-methyl-D-aspartate-induced burst firing in rat ventral tegmental neurons.
Seutin, Vincent ULg; Johnson, S. W.; North, R. A.

in Neuroscience (1994), 58(1), 201-6

Intracellular microelectrode recordings were made from dopamine-containing neurons of the ventral tegmental area or substantia nigra zona compacta in rat brain slices in vitro. The firing pattern of the ... [more ▼]

Intracellular microelectrode recordings were made from dopamine-containing neurons of the ventral tegmental area or substantia nigra zona compacta in rat brain slices in vitro. The firing pattern of the neurons was switched from a tonic, single-spike pattern to a burst firing mode by adding N-methyl-D-aspartate (20 microM) to the superfusing solution; after adding tetrodotoxin the membrane potential underwent rhythmical oscillations of 20-40 mV at 0.5-2 Hz. Baclofen (1 microM) and dopamine (30 microM) hyperpolarized the neurons; when the potential was restored to its original level, the oscillations of potential and/or burst firing were not observed, but the tonic firing pattern was restored. These effects of baclofen and dopamine were prevented by barium (1 mM), which also prevented the membrane hyperpolarization. Oscillations of membrane current of a similar frequency were observed when the somatic membrane was voltage-clamped at -60 mV; these were also blocked by barium (1 mM). It is concluded that the oscillations in membrane potential observed with N-methyl-D-aspartate are generated predominantly at a dendritic location which is not voltage-clamped with an electrode at the soma. Baclofen and dopamine inhibit the oscillations by increasing the potassium conductance and hyperpolarizing the dendrites. [less ▲]

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See detailA propos d'un cas de chylothorax compliquant une sclérose de varices oesophagiennes
Detry, Olivier ULg; Dekoster, Guy ULg; Honoré, Pierre ULg et al

in Lyon Chirurgical (1994), 90(1), 45-47

Chylothorax is an exceptional complication of endoscopic sclerotherapy of bleeding esophageal varices. We found only three cases in the literature. We report a fourth observation. We discuss the different ... [more ▼]

Chylothorax is an exceptional complication of endoscopic sclerotherapy of bleeding esophageal varices. We found only three cases in the literature. We report a fourth observation. We discuss the different etiologies and the different therapeutic approaches of these unusual chylothorax. [less ▲]

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See detailSubcellular Localization and Compartmentation of Thiamine Derivatives in Rat Brain
Bettendorff, Lucien ULg; Wins, Pierre; Lesourd, Monique

in Biochimica et Biophysica Acta (1994), 1222(1), 1-6

The subcellular distribution of thiamine derivatives in rat brain was studied. Thiamine diphosphate content was highest in the mitochondrial and synaptosomal fractions, and lowest in microsomal, myelin ... [more ▼]

The subcellular distribution of thiamine derivatives in rat brain was studied. Thiamine diphosphate content was highest in the mitochondrial and synaptosomal fractions, and lowest in microsomal, myelin and cytosolic fractions. Only 3-5% of total thiamine diphosphate was bound to transketolase, a cytosolic enzyme. Thiamine triphosphate was barely detectable in the microsomal and cytosolic fraction, but synaptosomes were slightly enriched in this compound compared to the crude homogenate. Both myelin and mitochondrial fractions contained significant amounts of thiamine triphosphate. In order to estimate the relative turnover rates of these compounds, the animals received an intraperitoneal injection of either [14C]thiamine or [14C]sulbutiamine (isobutyrylthiamine disulfide) 1 h before decapitation. The specific radioactivities of thiamine compounds found in the brain decreased in the order: thiamine > thiamine triphosphate > thiamine monophosphate > thiamine diphosphate. Incorporation of radioactivity into thiamine triphosphate was more marked with [14C]sulbutiamine than with [14C]thiamine. The highest specific radioactivity of thiamine diphosphate was found in the cytosolic fraction of the brain, though this pool represents less than 10% of total thiamine diphosphate. Cytosolic thiamine diphosphate had a twice higher specific radioactivity when [14C]sulbutiamine was used as precursor compared with thiamine though no significant differences were found in the other cellular compartments. Our results suggest the existence of two thiamine diphosphate pools: the bound cofactor pool is essentially mitochondrial and has a low turnover; a much smaller cytosolic pool (6-7% of total TDP) of high turnover is the likely precursor of thiamine triphosphate. [less ▲]

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See detailMaigret dans ses rapports avec les classes privilégiées
Mouton, Charles ULg

in Revue Générale (1994), 5

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See detailLes manifestations neurologiques de l'infection a Borrelia burgdorferi (maladie de Lyme).
PEPIN, Jean-Louis ULg; Bastings, Eric; Lenaerts, Marc ULg et al

in Revue Médicale de Liège (1994), 49(11), 603-10

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See detailThe cognitive approach to familiar face processing in human subjects
Brédart, Serge ULg; Bruyer, R.

in Behavioural Processes (1994), 33(1-2), 213-232

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See detailFIL2, an extracellular Leucine-Rich Repeat protein, is specifically expressed in Antirrhinum flowers.
Steinmayr, M.; Motte, Patrick ULg; Sommer, H. et al

in Plant Journal (The) (1994), 5(4), 459-67

The expression of the Antirrhinum gene FIL2 is affected in mutants of the homeotic transcription factor DEFICIENS. Northern and Western blot analyses showed that FIL2 in wild-type Antirrhinum flowers is ... [more ▼]

The expression of the Antirrhinum gene FIL2 is affected in mutants of the homeotic transcription factor DEFICIENS. Northern and Western blot analyses showed that FIL2 in wild-type Antirrhinum flowers is expressed weakly in the petals and more abundantly in the reproductive organs; the gene is active in the filaments and anthers of stamens, and in the stigma and transmitting tissue of the carpels. The FIL2 protein is glycosylated with high mannose type glycan chains and is located in the middle lamella of the extracellular matrix. The amino acid sequence contains 10 tandem repeats, the composition of which is similar to the Leucine-Rich Repeat (LRR) motif found in mammals, Drosophila and yeast. The possibility that FIL2 might be a component of a cellular signalling mechanism, involving LRR-mediated protein-protein interactions is discussed. [less ▲]

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See detail"Des biet ou lombardeau": La langue d'un écrivant belgoroman du début du 17e siècle
Boutier, Marie-Guy ULg; Chambon, Jean-Pierre

in Revue de Linguistique Romane (1994), 58

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See detailIs aprotinin worth the risk in total hip replacement?
Janssens, Marc ULg; Joris, Jean ULg

in Anesthesiology (1994), 81(2), 518-519

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See detailRobotique pédagogique, d'un colloque à l'autre : vers l'émergence d'une communauté scientifique ?
Denis, Brigitte ULg; Baron, G. L.

in Sciences et Techniques Educatives [= STE] (1994), 1

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See detailAnti-LFA-1 (CD11a) monoclonal antibody interferes with the induction of neonatal tolerance to alloantigens
Schurmans, Stéphane ULg; Gonzalez, A.; Revilla, C. et al

in European Journal of Immunology (1994), 24

The injection of (C57BL/6 x BALB/c)F1 spleen cells into newborn BALB/c mice results in the induction of a specific cytotoxic T lymphocyte (CTL) tolerance to the alloantigens. On the contrary, alloreactive ... [more ▼]

The injection of (C57BL/6 x BALB/c)F1 spleen cells into newborn BALB/c mice results in the induction of a specific cytotoxic T lymphocyte (CTL) tolerance to the alloantigens. On the contrary, alloreactive CD4+ T cells persist in the host and are still able to activate autoreactive F1 B cells to produce autoantibodies. This state of "split tolerance" is closely associated with the development of a lupus-like autoimmune syndrome. The LFA-1 integrin plays a relevant role in homing, intercellular adhesion and tranduction of co-stimulatory signals in leukocytes. Because of the beneficial effects of anti-LFA-1 monoclonal antibodies (mAb) treatment in various models of organ transplantation and autoimmune disease, we have investigated if such a treatment could interfere with the induction of neonatal tolerance or the development of the autoimmune syndrome in F1 cell-injected newborn mice. For this purpose, BALB/c mice neonatally injected with F1 cells were treated from day 1 up to day 15 with a non-cytotoxic anti-LFA-1 (CD11a) mAb. Anti-LFA-1 mAb treatment interfered with the persistence of a stable chimerism and with the establishment of CTL tolerance, as shown by rejection of allogeneic skin grafts and F1 B cells, and by a normal in vitro CTL activity against the corresponding alloantigens. As a consequence, these mice did not develop the characteristic autoimmune features seen in close association with an effective induction of CTL tolerance to alloantigens. These results stress the importance of the interactions between LFA-1 and its ligands during the neonatal induction of tolerance to alloantigens [less ▲]

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See detailAgglomérations morphologiques et fonctionnelles, l’apport de la télédétection urbaine
Donnay, Jean-Paul ULg

in Acta Geographica Lovaniensia (1994), 34

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See detailEndoscopic management of ectopic pregnancy.
Donnez, Jacques; NISOLLE, Michelle ULg

in Bailliere's Clinical Obstetrics & Gynaecology (1994), 8(4), 707-2

The rationale for the conservative management of ectopic pregnancy is the preservation of reproductive potential. Removal of trophoblast through a linear incision (salpingotomy) can be easily performed by ... [more ▼]

The rationale for the conservative management of ectopic pregnancy is the preservation of reproductive potential. Removal of trophoblast through a linear incision (salpingotomy) can be easily performed by endoscopy. The injection of vasopressin into the broad ligament is required in less than 10% of cases and its routine use is not recommended because of the risk of severe side-effects. The techniques in cases of isthmic or cornual tubal pregnancy are also described. Other alternatives such as expectant management, methotrexate, RU 486 and prostaglandins have also recently been proposed. Although methotrexate therapy has been demonstrated to be effective in cases of unruptured tubal pregnancy, further studies are needed to determine whether or not this medical therapy is a safer option than laparoscopic surgery and to compare the subsequent intrauterine and recurrent ectopic pregnancy rates. Endoscopic salpingotomy is an efficacious procedure. Indeed, residual trophoblast is found in only 5% of cases after this surgical procedure. In these cases of persistent trophoblast, methotrexate is proposed as the medical approach of choice. Evaluation of the postoperative fertility after linear salpingotomy demonstrates an intrauterine pregnancy rate of 63% and a recurrent ectopic pregnancy rate of 8%. In conclusion, endoscopic management of tubal pregnancy is a safe and efficacious therapy. The contraindications are relative and depend essentially on the surgeon's experience. [less ▲]

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See detailMétaux lourds et isotopes stables du carbone dans la matière particulaire: distribution sur le plateau continental nord-ouest européen
Dauby, Patrick ULg; Mosora, Fiorentina; Frankignoulle, Michel et al

in Bulletin de la Société Royale des Sciences de Liège (1994), 63

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See detailOxygen Transport Chain in Double-Muscled Blue Belgian Cattle
Lekeux, Pierre ULg; Amory, Hélène ULg; Desmecht, Daniel ULg et al

in British Veterinary Journal (The) (1994), 150(5, Sep-Oct), 463-471

The physiological peculiarities of the oxygen transport chain in double-muscled Blue Belgian cattle are described. The investigations performed at several levels of the oxygen transport chain suggest that ... [more ▼]

The physiological peculiarities of the oxygen transport chain in double-muscled Blue Belgian cattle are described. The investigations performed at several levels of the oxygen transport chain suggest that the increased susceptibility of these cattle to stress, resulting mainly in respiratory diseases, is due to an insufficient functional reserve capacity mainly involving the pulmonary and cardiovascular systems. The resulting lack of 'functional hardiness' of the oxygen transport chain is seen in those double-muscled cattle which do not react in an appropriate or predictable way when submitted to a hostile environment. [less ▲]

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See detailComplete Dna-Sequence Of Yeast Chromosome-Xi
Dujon, Bernard; Esteban, Pf.; Fernandes, L. et al

in Nature (1994), 369(6479),

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See detailTechnical Efficiency and Productivity Growth in an Era of Deregulation: the Case of Airlines
Distexhe, Véronique; Perelman, Sergio ULg

in Schweizerische Zeitschrift für Volkswirtschaft und Statistik = Revue Suisse d'Economie Politique et de Statistique (1994), (130), 669-689

In this paper we measure technical efficiency and productivity gains in airline activities. Non-parametric frontiers and Malmquist indices of productivity are estimated for thirty-three airlines observed ... [more ▼]

In this paper we measure technical efficiency and productivity gains in airline activities. Non-parametric frontiers and Malmquist indices of productivity are estimated for thirty-three airlines observed over the period 1977-1988. We identify three sources of growth: technological progress, efficiency change and route network characteristics. The results bring to light the reasons that pushed several airlines to merge when markets were deregulated. [less ▲]

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See detailBI-BASED 2223 SUPERCONDUCTING POLYCRYSTALLINE MATERIALS PREPARED BY EITHER A SOLID-STATE ROUTE OR A GLASSY MATRIX PRECURSOR METHOD - CHEMICAL-ANALYSIS AS WELL AS ELECTRICAL AND THERMAL TRANSPORT-PROPERTIES
Cloots, Rudi ULg; Bougrine, Hassan ULg; HOUSSA, M. et al

in Physica C (1994), 231(3-4), 259-270

Two routes have been followed in order to prepare Bi1.7Pb0.3Sr2Ca2Cu3O(y) superconducting materials. Bi1.7Pb0.3CuO4 is always used as one of the starting basic materials. The first route involves a new ... [more ▼]

Two routes have been followed in order to prepare Bi1.7Pb0.3Sr2Ca2Cu3O(y) superconducting materials. Bi1.7Pb0.3CuO4 is always used as one of the starting basic materials. The first route involves a new experimental procedure based on the solid state synthesis of separate intermediate phases, mixed together in a two (Bi1.7Pb0.3CuO4 + 2SrCaCuO3), three (Bi1.7Pb0.3CuO4+2SrCuO2+2CaCO3) or four (Bi1.7Pb0.3CuO4+(1/12)Sr8Ca6Cu24O41 + (3/2)CaCO3 + (4/3)SrCO3) powder process. Electric resistivity versus temperature measurements are presented. Even though the T(c)(0) of each sample is above 100 K, X-ray diffraction shows that the main phase is the 2212 phase in each case. Relatively pure 2223 materials have, however, successfully been produced by the second method, which starts from a glassy intermediate phase and involves a so-called 'matrix' method. The glass precursor phase is composed of one (Bi1.7Pb0.3CuO4), two (Bi1.7Pb0.3CuO4 + 2CaCO3), and three (Bi1.7Pb0.3CuO4 + (3/2)CaCO3 + (4/3)SrCO3) components as for the solid state routes. The role of both the added alkaline earth crystalline compounds and the glass matrix precursors in this second method turns out to be very important. We propose a schematic structural model in order to explain the selectivity of the starting materials. SrCaCuO3 is found to be a good precursor of the 2212 phase, while SrCuO2 gives rise to the 2223 phase. It seems that the presence of CaCO3 in the glassy intermediate phase, thus acting as a cation reservoir, is very useful for the production of the 2223 phase. Electric resistivity, thermal conductivity and thermopower versus temperature measurements are also presented and discussed in terms of intergrowths and variations of cationic compositions in the Bi-based layers. [less ▲]

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See detailEffect of recombinant human erythropoietin on platelets in patients with anemia of renal failure: correlation of platelet count with erythropoietic activity and iron parameters.
Beguin, Yves ULg; Loo, Martine; R'Zik, Samir ULg et al

in European Journal of Haematology (1994), 53(5), 265-70

We examined the effect of treatment with rHuEpo on platelet counts in 61 hemodialysis patients and correlated them with changes in erythropoietic activity, iron status and inflammation. Platelets (10(9)/1 ... [more ▼]

We examined the effect of treatment with rHuEpo on platelet counts in 61 hemodialysis patients and correlated them with changes in erythropoietic activity, iron status and inflammation. Platelets (10(9)/1) increased from 220 +/- 80 to 245 +/- 102 after 14 days and stabilized at that level up to day 90 (p < 0.0001). The increment was similar in complete or partial responders but was not observed in failures. Serum transferrin receptor (sTfR, a measure of total erythropoiesis) and Het rose much more progressively, but relative platelet increments correlated with relative increases in sTfR and Hct. Relative platelet increments correlated inversely with relative changes of SeFe or transferrin saturation, but not with their absolute values, nor with baseline ferritin or its progressive decrease. Although baseline platelet count was 12% higher in patients with inflammation and correlated with serum haptoglobin, relative increases were similar in patients with or without inflammation. In conclusion, rHuEpo produced a clinically minor but consistent elevation of platelet counts. These modifications were not related primarily to modifications in iron stores, functional iron deficiency, or inflammation, but paralleled the expansion of erythropoietic activity. The results suggest that rHuEpo has a small positive effect on platelet production, but it cannot be ruled out that this could be partially mediated through functional iron deficiency. [less ▲]

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See detailConformal invariance and degrees of freedom in the QCD string
Dienes, Keith R; Cudell, Jean-René ULg

in Physical Review Letters (1994), 72

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See detailUne contrefaçon liégeoise exemplaire : les Œuvres du philosophe bienfaisant (1764)
Droixhe, Daniel ULg

in Bulletin de la Société Royale Le Vieux-Liège (1994), 265

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See detailRôle de la chirurgie carotidienne dans la prévention de l'infarctus cérébral
Limet, Raymond ULg; DESIRON, Quentin ULg; DETRY, Olivier et al

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1994), 149(5-7), 299-305306-7

A significant part of transient or permanent cerebral ischemic attacks (CIA) are due to arterio-arterial emboli issued from carotid plaques. Surgery for carotid disobstruction aims to take out emboligenic ... [more ▼]

A significant part of transient or permanent cerebral ischemic attacks (CIA) are due to arterio-arterial emboli issued from carotid plaques. Surgery for carotid disobstruction aims to take out emboligenic plaques by endarterectomy (associated to angioplasty or not). The adversaries of surgical treatment sustain two main assertions: 1. carotid stenoses are not very dangerous, because the definitive thromboses they create are easily compensated by the development of collaterals, so that the risk for stroke is low. 2. this low and late risk of spontaneous carotid thrombosis is not greater than the immediate one following carotid surgery. Those objections have been encountered in randomized North American studies (Nascet [less ▲]

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See detailPretreatment minimal staging for non-small cell lung cancer: an updated consensus report
Goldstraw; Rocmansb; Ball et al

in Lung Cancer (1994), 11(supp 3), 1-4

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See detailFear reactions of ewes to photographic images
Vandenheede, Marc ULg; Bouissou, Marie-France

in Behavioural Processes (1994), 32

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See detailTechnical Study of Some Major Parameters Influencing the Performances of an Aerosol Delivery Equipment Suitable for Calves
Genicot, Bruno; Peckova, M.; Close, Roland et al

in Veterinary Research (1994), 25(5), 468-77

Aerosol delivery equipment, suitable for the treatment of bovine respiratory dysfunctions and including 2 parallelly positioned jet nebulizers, was studied in depth in order to determine the optimal ... [more ▼]

Aerosol delivery equipment, suitable for the treatment of bovine respiratory dysfunctions and including 2 parallelly positioned jet nebulizers, was studied in depth in order to determine the optimal working conditions in the field. Indeed, some factors might reasonably alter the performance of this equipment. Among these factors, the influences of the parallel position of jet nebulizers (in order to accommodate the breathing requirements of the cattle and achieve a rapid treatment), of the long feed pipe delivering compressed air (in order to keep the animal away from the compressor unit), and finally of the ambient temperature were studied, this equipment being essentially used during the winter season. This equipment could accommodate the breathing needs of cattle weighing up to 225 kg if a pressure of 600 kPa was developed upstream to the nebulizers. The rate of atomization was significantly reduced when working at ambient air temperatures (272.25 K < T < 274.65 K) close to those encountered in winter. This was especially true when pressure upstream to the nebulizers did not exceed 500 kPa. The immersion of the feed pipe for compressed air in hot water led to an increase in the rate of atomization without raising evaporative water losses, and reduced the drop in temperature in the nebulizer solution. Finally, the rate of atomization significantly increased when the face mask including the nebulizers was maintained so that the nebulizers were in a vertical position or at an angle not less than 60 degrees with respect to the ground. [less ▲]

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See detailMuscle Fibre Type and Size, and Muscle Capillary Density in Young Double-Muscled Blue Belgian Cattle
Stavaux, D.; Art, Tatiana ULg; Mc Entee, Kathleen ULg et al

in Zentralblatt für Veterinarmedizin. Reihe A (1994), 41(3), 229-236

Bovine muscle biopsies were analysed for fiber type and capillary density by the acid ATP-ase and amylase-PAS methods respectively. Samples obtained from Belgian blue double muscled (DM) calves were ... [more ▼]

Bovine muscle biopsies were analysed for fiber type and capillary density by the acid ATP-ase and amylase-PAS methods respectively. Samples obtained from Belgian blue double muscled (DM) calves were compared for their fibre type, size and vascularization with samples from Friesian (F) calves. The animals were sampled both at 2 and 7 months of age. Changes in histochemical composition occurring with ageing, independently of the breed, and differences related to the muscle sampled by comparing biopsies obtained from the longissimus dorsi (LD) and gluteobiceps (GB) muscles in animals of both breed were also investigated. Independently of age and muscle, fibre type I percentage and area were significantly higher in F than in DM muscles. Type IIa area was significantly larger in F than in DM, while fibre type IIb percentage and area were higher in DM. The number of capillaries/mm2 was significantly higher in F than in DM. Fibre type IIa and IIb percentage as well as the diameter of the three fibre types was significantly higher in the oldest animals. Finally, independently of age and breed, fibre type I and IIb percentages were significantly higher in LD but lower in GB. The results mainly demonstrated that Belgian blue DM muscles present a higher proportion of IIb fibres and a lower capillary supply than F muscles. [less ▲]

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See detailLa métropolisation, une nouvelle donne
Merenne-Schoumaker, Bernadette ULg

in Acta Geographica Lovaniensia (1994), (34), 165-174

The recent economic growth of many big cities has led to the new concept of "metropolization" and to numerous research based on new models of urban growth. In trying to draw up on this theme, one has ... [more ▼]

The recent economic growth of many big cities has led to the new concept of "metropolization" and to numerous research based on new models of urban growth. In trying to draw up on this theme, one has tackled successively four points: the concepts of metropolis and metropolization, the metropolization process, the metropolization and the city systems, the metropolization in Europe and Belgium. [less ▲]

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See detailCas d'étymologie double dans le FEW (V)
Boutier, Marie-Guy ULg; Büchi, Eva; Chambon, Jean-Pierre et al

in Travaux de linguistique et de philologie (1994), 32

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See detailConnection and frame design for economy
Anderson, D.; Colson, A.; Jaspart, Jean-Pierre ULg

in Bouwen met Staal (1994), n°117

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See detailAnalysis by in Situ Hybridization of Cytokine Mrnas Expression in Thymic Nurse Cells
Deman, J.; Humblet, Chantal ULg; Martin, M. T. et al

in Advances in Experimental Medicine and Biology (1994), 355

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See detailFluid transfer in anorthosites and related rocks from Rogaland (Southwest Norway): Evidence from stable isotopes
Wilmart, Edith; Pineau, Françoise; Réjou-Michel, A. et al

in Earth & Planetary Science Letters (1994), 125

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See detailTranscription and expression analysis, using lacZ and phoA gene fusions, of Mycobacterium fortuitum beta-lactamase genes cloned from a natural isolate and a high-level beta-lactamase producer.
Timm, J; Perilli, M G; Duez, Colette ULg et al

in Molecular Microbiology (1994), 12(3), 491-504

The gene encoding a class A beta-lactamase was cloned from a natural isolate of Mycobacterium fortuitum (blaF) and from a high-level amoxicillin-resistant mutant that produces large amounts of beta ... [more ▼]

The gene encoding a class A beta-lactamase was cloned from a natural isolate of Mycobacterium fortuitum (blaF) and from a high-level amoxicillin-resistant mutant that produces large amounts of beta-lactamase (blaF*). The nucleotide sequences of the two genes differ at 11 positions, including two in the region upstream from the coding sequence. Gene fusions to Escherichia coli lacZ and transcription and expression analysis of the cloned genes in Mycobacterium smegmatis indicated that high-level production of the beta-lactamase in the mutant is mainly or wholly due to a single base pair difference in the promoter. These analyses also showed that transcription and translation start at the same position. A comparison of the amino acid sequence of BlaF, as predicted from the nucleotide sequence, with the determined N-terminal amino acid sequence indicated the presence of a typical signal peptide. The fusion of blaF (or blaF*) to the E. coli gene phoA resulted in the production of BlaF-PhoA hybrid proteins that had alkaline phosphatase activity. These results demonstrate that phoA can be used as a reporter gene for studying protein export in mycobacteria. [less ▲]

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See detailR. Sacré, « Les Negro Spirituals et les Gospel Songs »
Pirenne, Christophe ULg

in Cahiers de Clio (1994), 119

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See detailOptimisation du plan parcellaire d'une exploitation agricole: une application de la theorie des graphes.
Dupont, Pascal ULg

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(3),

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See detailC.R. du Mystère de la Résurrection. (Angers, 1456)
Henrard, Nadine ULg

in Lettres Romanes (1994), XLVIII(1-2), 112-114

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See detailMarqueurs tumoraux
Charlier, Corinne ULg; Plomteux, Guy ULg

in Focus Diagnostica (1994), 2

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See detailPlace of MALT in the immune defence system.
Heinen, Ernst ULg

in Advances in Experimental Medicine and Biology (1994), 355

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See detailParametric Cubic Equations For Modeling Moldboard Plow Surfaces
Ravonison, Nm.; Destain, Marie-France ULg

in Soil & Tillage Research (1994), 31(4), 363-373

Mouldboard shape identification is needed to compare and analyse the performance of different plough bottoms. The paper presents a method for describing an existing mouldboard mathematically. The ... [more ▼]

Mouldboard shape identification is needed to compare and analyse the performance of different plough bottoms. The paper presents a method for describing an existing mouldboard mathematically. The technique used is based on a Bezier form of three dimensional parametric cubics and it focuses on an algorithm to improve the efficiency of approximation of a theoretical surface and the actual one. The method is well suited to describing mouldboard designs. [less ▲]

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See detailQue peut-on attendre des marqueurs immunohistochimiques du mélanome?
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Nouvelles Dermatologiques (1994), 13

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See detailBiostatistical studies of Western European allogamous populations of the Epipactis helleborine (L.) Crantz species group (Orchidaceae)
Tyteca, D.; Dufrêne, Marc ULg

in Systematic Botany (1994), 19(3), 424-442

[No abstract available]

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See detailFunctional Sites Of The Bovine Leukemia-Virus Envelope Glycoproteins Using Structural And Immunological Data
Callebaut, I.; Mornon, Jp.; Burny, A. et al

in Archives Internationales de Physiologie de Biochimie et de Biophysique (1994), 102(2),

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See detailAnevrysme femoral superficiel rompu dans le cadre d'une neurofibromatose. A propos d'un cas
Van Damme, Hendrik ULg; Deprez, Manuel ULg; De Leval, Laurence ULg et al

in Journal des Maladies Vasculaires (1994), 19(1), 62-5

The authors observed the spontaneous rupture of a dysplastic superficial femoral artery in a 47 years old patient with Von Recklinghausen disease. The patient presents a gigantism of his right lower limb ... [more ▼]

The authors observed the spontaneous rupture of a dysplastic superficial femoral artery in a 47 years old patient with Von Recklinghausen disease. The patient presents a gigantism of his right lower limb. On angiography, the femoropopliteal axis is polyaneurysmal and there is evidence of rupture at mid-thigh. The diseased artery is excluded by interposition of a dacron prosthesis, with reimplantation of the deep femoral artery. Histology shows fibrohyalin thickening of the intima. Dysplasia of large limb arteries is excessively rare in Von Recklinghausen disease. [less ▲]

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See detailHooliganisme et extrémisme
Comeron, Manuel ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1994), 1

Les dimensions de racisme et d'extrémisme politique sont liés aux problèmes de sécurité et de violence posés par les supporters de football.

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See detailVerticalization of behavior elicited by dopaminergic mobilization is qualitatively different between C57BL/6J and DBA/2J mice
Tirelli, Ezio ULg; Witkin, J. M.

in Psychopharmacology (1994), 116(2), 191-200

Behavioral effects of dopaminergic stimulation were compared for C57BL/6J mice and DBA/2J mice. Effects of apomorphine (APO) alone and in combination with cocaine (COC) were assessed using a time-sampling ... [more ▼]

Behavioral effects of dopaminergic stimulation were compared for C57BL/6J mice and DBA/2J mice. Effects of apomorphine (APO) alone and in combination with cocaine (COC) were assessed using a time-sampling technique that classified climbing and leaning in separate categories. Climbing occurred in DBA/2J mice only at doses of APO that were 16 times higher than the smallest effective dose in C57BL/6J mice, but relative to baseline values, effects were comparable. Whereas DBA/2J mice showed dose-dependent leaning under APO, C57BL/6J mice exhibited significantly increased leaning only after the highest APO dose. When given alone, COC produced significant climbing, but not leaning or gnawing, in either strain. COC potentiated APO-induced climbing and gnawing in both strains but did not consistently change APO-induced leaning in either strain. APO alone reduced locomotor activity and attenuated COC-induced hyperkinesia. ((c) 1997 APA/PsycINFO, all rights reserved) [less ▲]

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See detailArt et technique
Duchesne, Jean-Patrick ULg

in Art&fact (1994), 13

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See detailConditional watershed segmentation for grain boundary reconstruction
Pirard, Eric ULg; Delanaye, Annick ULg

in Acta Stereologica (1994), 14(1), 23-28

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See detailRécidive post-opératoire de la maladie de Crohn après chirurgie curatrice
Belaiche, Jacques ULg; Louis, Edouard ULg

in Médecine et Hygiène (1994), 52

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See detailDe limite en frontière : le monde à la mesure de l'homme
Bachelet, Jean-François ULg

in Revue de l'Institut de Sociologie (1994), 3-4

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See detailEst-ce ainsi que les jeunes Belges lisent? Résultat d'une enquête internationale
Lafontaine, Dominique ULg; Lafontaine, Annette ULg

in Enjeux : Revue de Formation Continuée et de Didactique du Français (1994), 31(7), 31

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See detailStereoselective syntheses of cyclopropane derivatives from γ-alkoxy-α,β-unsaturated carbonyl compounds and methylene transfer reagents
Krief, Alain; Dumont, Willy; Lecomte, Philippe ULg

in Polish Journal of Chemistry (1994), 68

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See detailLa maladie de Lyme : une nouvelle maladie?
Mainil, Jacques ULg

in Annales de Médecine Vétérinaire (1994), 138

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See detailGeometric control of a pyridoxal-catalyzed aldol condensation
Koh, John T.; Delaude, Lionel ULg; Breslow, Ronald

in Journal of the American Chemical Society (1994), 116(25), 11234-11240

A chiral cyclophane derivative of pyridoxal has been synthesized that has amino groups oriented specifically over one face of the cofactor. The compound catalyzes the formation of threonine and allo ... [more ▼]

A chiral cyclophane derivative of pyridoxal has been synthesized that has amino groups oriented specifically over one face of the cofactor. The compound catalyzes the formation of threonine and allo-threonine from glycine and acetaldehyde with enantioinductions that are a function of pH, reversing the optical selectivity between low pH and high pH. The stereochemical results are compared with those of structurally related pyridoxal cyclophanes that lack titratable catalytic groups. Explanations are advanced for this stereochemical reversal and for the otherwise surprising preference of most of these compounds to react on the more hindered face of the pyridoxal. Models indicate that the transamination intermediate is distorted by the transannular chain, and stereoelectronic arguments predict that this distortion should lead to reaction on the face that carries the chain, as observed. The stereochemical reversal with the attached (dimethylamino)alkyl group, as a function of pH, may reflect catalysis by the protonated form, but metal coordination by the basic form cannot be excluded. [less ▲]

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See detailReduction of the acute bioavailability of metformin by the alpha-glucosidase inhibitor acarbose in normal man.
Scheen, André ULg; de Magalhaes, A. C.; Salvatore, T. et al

in European Journal of Clinical Investigation (1994), 24 Suppl 3

In a double-blind cross-over study, we investigated a possible influence of the alpha-glucosidase inhibitor acarbose on the bioavailability of the biguanide compound metformin. Each of the six healthy ... [more ▼]

In a double-blind cross-over study, we investigated a possible influence of the alpha-glucosidase inhibitor acarbose on the bioavailability of the biguanide compound metformin. Each of the six healthy young male volunteers was randomly allocated during two consecutive 7 day periods to either acarbose (days 1-3: 3 x 50 mg day-1; days 4-7: 3 x 100 mg day-1) or placebo. At day 7 and 14 of the study, the overnight-fasted subjects ingested 1000 mg metformin with the first bite of a standardized breakfast (500 kcal; 60 g carbohydrates) and together with either placebo or 100 mg acarbose. Acarbose significantly (P < 0.05) reduced the meal-induced increase in blood glucose and plasma insulin levels. Acarbose induced a significant (P < 0.05) reduction in early (90, 120, 180 min) serum levels, peak concentrations (Cmax: 1.22 +/- 0.14 vs. 1.87 +/- 0.60 mg l-1) and area under the curve of metformin (AUC 0-540 min: 423 +/- 55 vs. 652 +/- 55 mg min l-1), but did not diminish its 24 h urinary excretion. In conclusion, acarbose significantly reduces the acute bioavailability of metformin in normal subjects. [less ▲]

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See detailThe use of large scale computer assisted tomography for the study of hydrodynamics in trickling filters
Toye, Dominique ULg; Marchot, Pierre ULg; Crine, Michel ULg et al

in Chemical Engineering Science (1994), 49(24B), 5271-5280

In this paper, a new experimental technique is proposed, based on X-ray tomography, allowing the analysis of the gas-liquid-solid phase distribution in trickling filters. Tomography refers to the cross ... [more ▼]

In this paper, a new experimental technique is proposed, based on X-ray tomography, allowing the analysis of the gas-liquid-solid phase distribution in trickling filters. Tomography refers to the cross-sectional imaging of an object from data collected by illuminating this object from many directions. The experimental set-up allows the scanning of transverse sections of rather large filters: up to 0.8 m diameter and 2 m height can be irradiated. Experiments were carried out both without and with liquid flow. In the absence of liquid, the reconstructed images give a view of the non-uniformity of the solid phase distribution. The images obtained are very complex because they result from the superposition of several distributions with different spatial scales. The existence of a first spatial scale is shown which allows separation of the properties belonging to the individual packing elements from those belonging to the bed scale. When liquid is flowing through the packed bed, the distribution of the liquid hold-up is clearly evidenced, despite the very low liquid film thickness. [less ▲]

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See detailChemically selected subclones of the CEM cell line demonstrate resistance to HIV-1 infection resulting from a selective loss of NF-kappa B DNA binding proteins.
Qian, J.; Bours, Vincent ULg; Manischewitz, J. et al

in Journal of Immunology (1994), 152(8), 4183-91

To delineate cellular genes that are required for optimal HIV-1 infection, CEM cells were subjected to treatment with the chemical mutagen ethylmethanesulfonate (EMS) and subclones were selected based on ... [more ▼]

To delineate cellular genes that are required for optimal HIV-1 infection, CEM cells were subjected to treatment with the chemical mutagen ethylmethanesulfonate (EMS) and subclones were selected based on their increased resistance to HIV-1 infection and reduced syncytium formation, despite relatively normal CD4 expression (20,000 to 25,000 receptors/cell). Two subclones with this phenotype demonstrated a diminished capacity of HIV-1 long terminal repeat-chloramphenicol acetyl transferase expression either after treatment with the protein kinase C activator PMA, or through Tat-mediated transactivation. In this study, we show that the cellular levels of the NF-kappa B DNA binding proteins (but not AP1 or SP1) are markedly reduced in these cell mutants both at the mRNA and protein levels, resulting in reduced nuclear localization of p50/p65 after PMA induction or treatment with the lymphokine TNF-alpha. Transient reconstitution with a plasmid expressing p50 resulted in partial recovery of PMA-inducible LTR-chloramphenicol acetyl transferase expression. These data suggest that, at least in the CEM T cell line, a selective reduction in the NF-kappa B DNA binding proteins is sufficient to curtail HIV-1 infection. [less ▲]

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See detailNeuropeptides cutanés
Tassoudji, Nazli ULg; Nikkels, Arjen ULg; Pierard, Gérald ULg

in Les Nouvelles Dermatologiques (1994), 13

The neuropeptides act as mediators in the transmission of nervous influx and as messengers between the nervous system and other cell populations. The skin contains numerous neuropeptides which are ... [more ▼]

The neuropeptides act as mediators in the transmission of nervous influx and as messengers between the nervous system and other cell populations. The skin contains numerous neuropeptides which are involved in the regulation of inflammation, immunomodulation, and thermoregulation. Cutaneous trophicity, pigmentation, and to a lesser extent sebaccous secretions are also influenced by neuropeptides. This review describes the functions of the most important neuropeptides encountered at the level of the skin. [less ▲]

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See detailLe tamoxifene dans le traitement du cancer du sein
Charlier, Corinne ULg; Colin, Claude ULg; Merville, Marie-Paule ULg et al

in Journal de Gynécologie, Obstétrique et Biologie de la Reproduction (1994), 23(7), 751-6

Tamoxifen is the most often prescribed non steroidal antioestrogenic agent in the world for breast cancer. Worldwide collaboration. has centralized the results, of different trials throughout the world on ... [more ▼]

Tamoxifen is the most often prescribed non steroidal antioestrogenic agent in the world for breast cancer. Worldwide collaboration. has centralized the results, of different trials throughout the world on oral adjuvant therapy in the early stages of breast cancer. A significative regression of the tumour was observed in most cases. Moreover, recent epidemiological studies suggest that tamoxifen could prevent new contralateral primary tumours. The risk of the disease should thus be reduced by the prophylactic use of antioestrogens such as tamoxifen. Investigations using a variety of models have evaluated the effect of tamoxifen on tumour promotion and cell growth. Tamoxifen-induced growth inhibition is associated with major changes in biochemical events in cultured human breast cancer cells including cell proliferation or growth factor production. Growth inhibition of oestrogen-responsive human breast cancer cells is associated with an induced secretion of autoinhibitory polypeptides (TGF beta) and an antagonistic effect on the synthesis of proliferative proteins (TGF alpha,...). The first step in the mechanism of action of the drug is binding of tamoxifen to the oestrogen receptors. Development of resistance to tamoxifen treatment is a great problem in treatment of breast cancer patients and the mechanism of resistance will require further study: under the influence of the drug, tumours could become remodelled as selected subpopulations emerge resistant-tamoxifen. The fact that some breast cancers which are oestrogen receptor-negative respond to antioestrogen suggests that parallel but separate pathways for oestrogen and antioestrogen action may exist. This paper summarizes the results of the most recent studies concerning this promising drug. [less ▲]

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See detailPyoverdine production is not the sole trait involved in the biological control of soil diseases by Pseudomonas fluorescens ATCC 17400.
Jacques, Philippe ULg; Cornelis, P.; Gaballa, A. et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1994), 102(B81),

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See detailTaqi Restriction-Fragment-Length-Polymorphisms For Growth-Hormone In Bovine Breeds And Their Association With Quantitative Traits
Sneyers, M.; Renaville, Robert ULg; Falaki, M. et al

in Growth Regulation (1994), 4(3),

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See detailAnalysis of the penA gene of Pseudomonas cepacia 249.
Joris, Bernard ULg; Galleni, Moreno ULg; Frère, Jean-Marie ULg et al

in Antimicrobial Agents and Chemotherapy (1994), 38(2), 407-8

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See detailMR1325693,Huang, Hou-Cheng and Usmani, Asif S.,Finite element analysis for heat transfer
Rochus, Pierre ULg

in Mathematical Reviews [=MR] (1994)

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See detailGénétique moléculaire des récepteurs olfactifs
Parmentier, M.; Vanderhaeghen, P.; Schurmans, Stéphane ULg et al

in Medecine Sciences : M/S (1994), 10

Les gènes codant pour les récepteurs olfactifs ont été isolés à partir d'une banque d'ADNc de la muqueuse olfactive. Ils constituent une famille très étendue (plusieurs centaines de gènes) codant pour des ... [more ▼]

Les gènes codant pour les récepteurs olfactifs ont été isolés à partir d'une banque d'ADNc de la muqueuse olfactive. Ils constituent une famille très étendue (plusieurs centaines de gènes) codant pour des récepteurs à sept passages transmembranaires couplés, par l'intermédiaire de protéines G, à l'activation de l'adénylyl cyclase et de la phospholipase C. La grande diversité des récepteurs olfactifs réside surtout dans les domaines transmembranaires III, IV, V et VI, qui portent les sites de liaison des ligands, les molécules odorantes, et répond sans doute à la diversité des ligands [less ▲]

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See detailLe contrôle de l'infection par le virus de la rhinotrachéite infectieuse bovine
Lemaire, Mylène; Pastoret, Paul-Pierre ULg; Thiry, Etienne ULg

in Annales de Médecine Vétérinaire (1994), 138

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See detailMechanisms of dexamethasone-induced insulin resistance in healthy humans.
Tappy, L.; Randin, D.; Vollenweider, P. et al

in Journal of Clinical Endocrinology and Metabolism (1994), 79(4), 1063-9

Insulin resistance may result from decreased muscle blood flow, impaired cellular glucose transport, or intracellular deficits of glucose metabolism. The mechanisms responsible for dexamethasone-induced ... [more ▼]

Insulin resistance may result from decreased muscle blood flow, impaired cellular glucose transport, or intracellular deficits of glucose metabolism. The mechanisms responsible for dexamethasone-induced insulin resistance were investigated in healthy human subjects. During a 2-h hyperinsulinemic clamp, dexamethasone decreased glucose uptake, oxidation, and nonoxidative glucose disposal during the first hour. During the second hour, glucose uptake was normalized by means of hyperglycemia; glucose oxidation, however, remained suppressed by dexamethasone. Dexamethasone also abolished the insulin-mediated increase in calf blood flow. When acipimox was administered during the clamps to correct glucocorticoid-induced inhibition of glucose oxidation, dexamethasone decreased whole body glucose uptake and nonoxidative glucose disposal in the same proportion as when no acipimox was administered. However, glucose oxidation and insulin-mediated calf blood flow were normalized after acipimox. During the second hour, exogenous glucose infusion was matched to that used in the control clamp and normalized whole body glucose uptake. However, hyperglycemia developed, indicating insulin resistance. It is concluded that dexamethasone 1) decreases glucose oxidation independently of glucose transport; this inhibition is reversed by acipimox; and 2) decreases whole body glucose uptake independently of increased lipolysis, decreased glucose oxidation, or an altered muscle blood flow. [less ▲]

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See detailErythropoietic activity and iron metabolism in autologous blood donors during recombinant human erythropoietin therapy.
Biesma, D. H.; Van de Wiel, A.; Beguin, Yves ULg et al

in European Journal of Clinical Investigation (1994), 24(6), 426-32

The use of recombinant human erythropoietin (rhEPO) to intensify the erythropoietic response in autologous donors may reduce homologous blood requirement. We studied the effect of subcutaneous rhEPO (500 ... [more ▼]

The use of recombinant human erythropoietin (rhEPO) to intensify the erythropoietic response in autologous donors may reduce homologous blood requirement. We studied the effect of subcutaneous rhEPO (500 U kg-1 body weight twice weekly during a 3 week period) on variables of erythropoiesis and iron metabolism in 62 autologous blood donors, of whom 32 received rhEPO (epo group) and 30 did not (control group). Patients donated only 2 units of blood and received oral iron in order to restrict phlebotomy-induced decrease of iron stores. Pre-phlebotomy haemoglobin concentration (14.0 +/- 0.8 g dl-1) was completely regenerated in the epo group at surgery (13.7 +/- 1.3 g dl-1); haemoglobin concentration in the control group fell from 13.5 +/- 1.4 g dl-1 to 11.6 +/- 1.4 g dl-1 after the phlebotomies and did not improve during the pre-operative phase. Total erythropoietic activity expressed as serum transferrin receptor concentration (sTfR) showed a 4-fold increase from 3.8 +/- 0.9 micrograms ml-1 to 14.9 +/- 4.8 micrograms ml-1 in the epo group. Effective erythropoietic activity measured by absolute reticulocyte count, however, declined after the fourth rhEPO injection in the epo group. Serum ferritin was lower in the epo group, but no differences in serum iron, transferrin concentration and transferrin saturation were observed between the groups. A marked increase in free erythrocyte protoporphyrin (FEP) was observed in the epo group, whereas FEP levels in the controls remained within normal ranges. Despite oral iron supplementation and the limited number of phlebotomies, the effect of rhEPO therapy in autologous donors is restricted by iron depletion. [less ▲]

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See detailA Consistent next-to-leading order QCD calculation of hadronic diffractive scattering
Cudell, Jean-René ULg; Nguyen, Bao

in Nuclear Physics B (1994), 420

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See detailCoupling and carbonylation of iodoaromatics and terminal alkynes or alkynols catalyzed by a dimeric palladium hydroxide
Delaude, Lionel ULg; Masdeu, Anna M.; Alper, Howard

in Synthesis (1994), (11), 1149-1151

The palladium(II) complex [(Ph(3)P)Pd(Ph)mu-OH)](2) is an effective catalyst for the coupling and carbonylation of alkynes and iodoarenes to give acetylenic ketones in 63-94% yields. Acetylenic hydroxy ... [more ▼]

The palladium(II) complex [(Ph(3)P)Pd(Ph)mu-OH)](2) is an effective catalyst for the coupling and carbonylation of alkynes and iodoarenes to give acetylenic ketones in 63-94% yields. Acetylenic hydroxy ketones were formed using secondary or tertiary alkynols as reactants. [less ▲]

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See detailMBO en Aandeelhouder
Corhay, Albert ULg; Herst, Arthur; Tourani Rad, Alireza

in Bedrifskunde (1994), 4

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See detailLe diabète insipide central : l'étiologie n'est pas toujours évidente
Geenen, Vincent ULg

in Actualité Médicale Belge (1994), 444

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See detailLe Marquis et les castrats. Note sur un tabou sadien
Durand, Pascal ULg

in Art&Fact (1994), 13

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See detailNatural-Convection Above Line Heat-Sources In Greenhouse Canopies
Aubinet, Marc ULg; Deltour, Jules

in International Journal of Heat and Mass Transfer (1994), 37(12),

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See detailSyndrome naviculaire : anatomie, étio-pathogénie, diagnostic et traitement
Gabriel, Annick ULg; Caudron, I.; Serteyn, Didier ULg et al

in Annales de Médecine Vétérinaire (1994), 138

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See detailUse of recombinant human erythropoietin after bone marrow transplantation in pediatric patients with acute leukemia: effect on erythroid repopulation in autologous versus allogeneic transplants.
Locatelli, F.; Zecca, M.; Pedrazzoli, P. et al

in Bone Marrow Transplantation (1994), 13(4), 403-10

We carried out a pilot study on the use of recombinant human erythropoietin (rHuEPO) in children undergoing allogeneic or mafosfamide-purged autologous BMT for ALL or AML. rHuEPO was administered ... [more ▼]

We carried out a pilot study on the use of recombinant human erythropoietin (rHuEPO) in children undergoing allogeneic or mafosfamide-purged autologous BMT for ALL or AML. rHuEPO was administered intravenously at a dose of 75 U/kg/day for 30 days after transplant. Ten rHuEPO-treated patients receiving allogeneic BMT and 10 given autologous BMT were compared with 15 allogeneic and 10 autologous historical controls. Endogenous EPO production was appropriate for the degree of anemia after autologous BMT. In these patients, rHuEPO did not accelerate erythroid repopulation and did not modify transfusion requirements. With allogeneic BMT, erythroid marrow activity increased faster in patients given rHuEPO than in controls and resulted in higher red cell production, the mean reticulocyte count on day +30 being 187 +/- 51 x 10(9)/l in treated patients versus 107 +/- 63 x 10(9)/l in controls (p < 0.01). The total number of RBC units administered was 1.7 +/- 1.3 in the rHuEPO group versus 5.1 +/- 3.0 in the control group (p < 0.001). The total number of platelet transfusions was 4.0 +/- 2.3 for patients given allogeneic BMT and receiving rHuEPO versus 8.4 +/- 6.8 for historical controls (p < 0.05) whereas it was similar in rHuEPO-treated and control autologous BMT patients.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailLes défis des familles recomposées
Guillaume, Jean-François ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1994), 6(novembre-décembre), 30-36

Dans un contexte de croissance des recompositions conjugales après divorce, la prise en charge des tâches parentales constitue un défi inédit, où il s'agit pour les uns de retrouver des repères bien ... [more ▼]

Dans un contexte de croissance des recompositions conjugales après divorce, la prise en charge des tâches parentales constitue un défi inédit, où il s'agit pour les uns de retrouver des repères bien connus, et pour les autres, d'imaginer un nouvel ordre éducatif. Une nouvelle histoire doit alors être créée, et dans ce "bricolage", chacun ne dispose pas des mêmes ressources pour trouver sa place. [less ▲]

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See detailLes spermatozoïdes ont-ils du nez ?
Vanderhaeghen, P.; Schurmans, Stéphane ULg; Parmentier, M. et al

in Medecine Sciences : M/S (1994), 10

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See detailAcute ethanol increases taurine but neither glutamate nor GABA in the nucleus accumbens of male rats: a microdialysis study.
Dahchour, Abdelkhader; Quertemont, Etienne ULg; De Witte, Philippe

in Alcohol & Alcoholism (1994), 29(5), 485-7

The effects of acute intraperitoneal administration of ethanol (1-3 g/kg body wt) on the extracellular concentrations of glutamate (GLU), taurine (TAU) and gamma-aminobutyric acid (GABA) in rat brain ... [more ▼]

The effects of acute intraperitoneal administration of ethanol (1-3 g/kg body wt) on the extracellular concentrations of glutamate (GLU), taurine (TAU) and gamma-aminobutyric acid (GABA) in rat brain nucleus accumbens were studied by the microdialysis technique coupled to HPLC-EC detection. Levels of GLU and GABA were not affected by ethanol, whereas those of TAU were increased by doses of the drug of 2-3 g/kg. [less ▲]

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See detailStereoelectronic properties of five anti-HSV-1 2′-deoxynucleosides analogues with heterocyclic substituents in the 5-position: A comparison with BVDU
Olivier, Anne; Creuven, Isabelle; Evrard, Christine ULg et al

in Antiviral Research (1994), 24

Structural and electronic characteristics of 5-(5-chlorothien-2-yl)-2′-deoxyuridine (I), 5-(furan-2-yl)-2′-deoxyuridine (II), 5-(5-bromofuran-2-yl)-2′-deoxyuridine (III), 5-(3-bromoisoxazol-5-yl)-2′ ... [more ▼]

Structural and electronic characteristics of 5-(5-chlorothien-2-yl)-2′-deoxyuridine (I), 5-(furan-2-yl)-2′-deoxyuridine (II), 5-(5-bromofuran-2-yl)-2′-deoxyuridine (III), 5-(3-bromoisoxazol-5-yl)-2′-deoxyuridine (V) and 5-(isoxazol-5-yl)-2′-deoxyuridine (IV) have been determined and compared to the BVDU (VI) characteristics in order to explain their respective affinity for the herpes simplex virus type 1 thymidine kinase (TK). Molecular structure of 5-(5-chlorothien-2-yl)-2′-deoxyuridine has been obtained using single crystal X-ray crystallography. Electrostatic potential maps, energy and topology of frontier orbitals were computed at the ab initio MO STO-3G and STO-3G* level. These studies reveal that the electrostatic potential energy maps are clearly dependent on the affinity of the compound for the enzyme. [less ▲]

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See detailCompte rendu de Mélanges Gabriel Sanders
George, Philippe ULg

in Moyen Age (Le) (1994)

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See detailFood Consumption in Belgium
Reginster-Haneuse, G.; Gosset, Christiane ULg

in Bibliotheca Nutritio et Dieta (1994), (51), 108-12

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See detailBénard-Marangoni instability in a viscoelastic Jeffreys' fluid layer
Lebon, Georgy ULg; Parmentier, Patrice; Teller, O. et al

in Rheologica Acta (1994), 33(4), 257-266

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See detailInvolvement Of The Cyclic Amp-Responsive Element-Binding Protein In Bovine Leukemia-Virus Expression In-Vivo
Adam, E.; Kerkhofs, P.; Mammerickx, M. et al

in Journal of Virology (1994), 68(9),

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See detailAnticorps anticytoplasme des polynucléaires neutrophiles (ANCA) dans les maladies inflammatoires du tube digestif
Lamproye, Anne ULg; Belaiche, Jacques ULg; Louis, Edouard ULg et al

in Acta Gastro-Enterologica Belgica (1994), 57(2, Mar-Apr), 171-6

Antineutrophil cytoplasmic antibodies have recently been demonstrated in sera of patients with inflammatory bowel disease. We are reporting here our experience among 94 patients with Crohn's disease and ... [more ▼]

Antineutrophil cytoplasmic antibodies have recently been demonstrated in sera of patients with inflammatory bowel disease. We are reporting here our experience among 94 patients with Crohn's disease and 25 with ulcerative colitis. The indirect immunofluorescence assay with alcohol fixed neutrophils has been used. The presence of antineutrophil cytoplasmic antibodies was significantly associated to the ulcerative colitis 61% VS 17% (p < 0.001). The fluorescence had a perinuclear pattern among all but one suffering from ulcerative colitis. Among the patients suffering from ulcerative colitis there was no relationship between the presence of antineutrophil cytoplasmic antibodies and the activity or the localisation of the disease. Among the 9 patients operated for their ulcerative colitis, 4 were ANCA positive and remained so after proctocolectomy. The existence of antineutrophil cytoplasmic antibodies is useful for the diagnosis of some unclassifiable colitis. Their presence may be used as an argument in favour of some disturbances of the immunoregulation of the disease. [less ▲]

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See detailDo canine scalene and sternomastoid muscles play a role in breathing?
De Troyer, A.; Cappello, M.; Brichant, Jean-François ULg

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1994), 76(1), 242-52

To assess the respiratory function of the scalene and sternomastoid muscles in the dog, we studied the effect of graded increases in inspiratory airflow resistance and single-breath airway occlusion on ... [more ▼]

To assess the respiratory function of the scalene and sternomastoid muscles in the dog, we studied the effect of graded increases in inspiratory airflow resistance and single-breath airway occlusion on the electrical activity of these muscles in 18 supine anesthetized spontaneously breathing animals. The sternomastoids never showed any activity, and the scalenes showed some inspiratory activity during occlusion in only two animals. The adoption of the prone position and bilateral cervical vagotomy did not affect this pattern. Hypercapnia also did not elicit any sternomastoid activity and induced scalene inspiratory activity during occlusion in only four of nine animals. On microscopic examination, however, both muscles were found to contain large numbers of spindles, suggesting that they have the capacity to respond to stretch. In addition, with increases in inspiratory resistance, both the sternum and ribs were displaced in the caudal direction. As a result, the scalenes demonstrated a gradual inspiratory lengthening and the normal inspiratory lengthening of the sternomastoids was accentuated. Additional studies in three unanesthetized animals showed consistent activity in the scalene and sternomastoid muscles during movements of the trunk and neck but no activity during breathing, including occluded breathing. These observations thus indicate that the alpha-motoneurons of the scalene and sternomastoid muscles in the dog have very small central respiratory drive potentials with respect to their critical firing threshold. In this animal, these muscles do not have a significant respiratory function. [less ▲]

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See detailThymus Involvement in Murine Acquired Immunodeficiency (Maids)
Colombi, Sonia; Deprez, Manuel ULg; de Leval, Laurence ULg et al

in Thymus (1994), 23(1), 27-37

Due to self-renewal of the peripheral pool of T-cells, adult thymectomy has normally little influence on immunocompetence. However, thymus might play a more important role in the setting of viral-induced ... [more ▼]

Due to self-renewal of the peripheral pool of T-cells, adult thymectomy has normally little influence on immunocompetence. However, thymus might play a more important role in the setting of viral-induced cytopathic effects on T-cells in the periphery. Therefore, thymus weight, cell numbers, and subset distribution were sequentially analysed after infection with RadLV-Rs, a viral mixture known to induce murine retrovirus induced immunodeficiency (MAIDS). Infection induced thymic atrophy (concerning organ weight as well as total cell number) which culminated seven weeks after inoculation. The atrophic process mostly reflected the depletion of double positive CD4+ CD8+ cells since their proportion sharply decreased around week 6. Single positive T-cells were less affected by the process. The proportion of B-cells progressively increased. Surprisingly, there was a strong correlation between the extent of atrophy and the frequency of B-cells in the thymus. Finally, an abnormal CD4+ T-cell subset lacking Thy-1 and previously described in the periphery also appeared in the thymus and its frequency was strongly correlated with the expansion of B-cells in this organ. [less ▲]

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See detailProtection du vendeur : les garanties légales et conventionnelles
Gosselin, Antoinette ULg

in Actualités du Droit (1994), (4), 933-972

The contribution envisages the protection of the seller as part of the cession of a firm in return for remuneration, giving rise to the payment of a price in exchange for the transfer of ownership. Sale ... [more ▼]

The contribution envisages the protection of the seller as part of the cession of a firm in return for remuneration, giving rise to the payment of a price in exchange for the transfer of ownership. Sale can concern a business or a number of actions or parts representative of an important party of the capital allowing to acquire the control of the society. The first party examines the lawful protection of the giving up, the second conventional guarantees in which giving it up can think to protect itself against the nonpayment of price by the seller. [less ▲]

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See detailFactors influencing between-laboratory variability of C-reactive protein results as evidenced by the Belgian External Quality Assessement (EQA) Scheme
Devleeschouwer, N.; Libeer, J. C.; Chapelle, Jean-Paul ULg et al

in Scandinavian Journal of Clinical & Laboratory Investigation (1994), 54(6), 435-40

Based on results from the Belgian External Quality Assessment (EQA) Scheme, we studied the main factors affecting the between-laboratory variation of C-reactive protein determination. Participants using ... [more ▼]

Based on results from the Belgian External Quality Assessment (EQA) Scheme, we studied the main factors affecting the between-laboratory variation of C-reactive protein determination. Participants using homogeneous systems with several calibration points generally achieved better performance. Working temperatures influenced the results to a lesser extent. The present study stresses the importance for EQA organizers to collect more detailed information about CRP analytical methods used by the participants. It also suggests that manufacturers should be more involved in the management of quality, in particular by striving for standardization of the material (kit and calibrator) they produce for CRP assay. [less ▲]

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See detailControl of the Illegal Administration of Natural Steroid Hormones in the Plasma of Bulls and Heifers
Scippo, Marie-Louise ULg; Degand, Guy ULg; Duyckaerts, Anne et al

in Analyst (1994), 119(12), 2639-44

In the context of the control of the illegal administration of natural steroid hormones in cattle husbandry, an attempt was made to establish the decision levels for sex steroid hormones in the plasma of ... [more ▼]

In the context of the control of the illegal administration of natural steroid hormones in cattle husbandry, an attempt was made to establish the decision levels for sex steroid hormones in the plasma of adult cattle, taking into account the effect of the treatment. Bulls and heifers were treated with two injections, at a two week interval, of an estradiol-testosterone cocktail. Steroid hormone and biochemical precursor concentrations were measured in plasma samples by using specific radioimmunoassays, before and after the treatment. When the treatment significantly (p < 0.05) modified a hormone concentration, a decision level was established for that hormone concentration. At each decision level, a score was assigned that represented the percentage of treated animals detected when the decision limit was applied. For heifers, 17 beta-estradiol and testosterone concentrations in plasma, which increased after the treatment, are the best criteria to use to detect treated animals, with decision limits of 20 pg ml-1 and 125 pg ml-1, respectively. In the instance of bulls, both testosterone and steroid biochemical precursor concentrations decreased in the plasma after the treatment. We proposed decision limits of 1500 pg ml-1 and 28 pg ml-1 for testosterone and androstenedione concentrations, respectively, the bulls displaying concentrations below these limits being positive. We observed that the repetition of the injection increased the score of the decision limit. The scores for testosterone are 70%, 14d after the first injection and 100% 14 d after the second injection, and for androstenedione, these scores are 60 and 100%, respectively. [less ▲]

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See detailObservations de coupes dans la terrasse T3 dans la vallée du Niger en aval de Niamey
Willems, Luc ULg; Bergoing, Jean-Pierre

in Revue de Géographie Alpine (1994), 5

Dans la région de Niamey, l'étendue et le nombre d'affleurements du complexe T3, appelé aussi terrasse moyenne, permettent de dresser une chronologie relative des événements climatiques survenus dans la ... [more ▼]

Dans la région de Niamey, l'étendue et le nombre d'affleurements du complexe T3, appelé aussi terrasse moyenne, permettent de dresser une chronologie relative des événements climatiques survenus dans la région durant son édification. Une étude systématique révèle une grande diversité dans les dépôts souvent assimilable aux variations locales de sédimentation. Cependant, cinq épisodes majeurs dans l'édification du complexe peuvent être dégagés et correspondent à autant de fluctuations climatiques durant une période qui s'étendrait de 20 000 à 12 000 BP. La découverte et l'observation de diaclases ainsi que des phénomènes de soutirage dans les dépôts pléistocènes montrent le rôle important qu'a pu jouer la fracturation du socle birrimien sur l'ensemble de la morphologie actuelle de la région de Niamey, en particulier sur le réseau hydrographique. [less ▲]

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See detailImportance des insectes ravageurs des cereales stockees en Belgique.
Letellier, C.; Haubruge, Eric ULg; Gaspar, Charles ULg

in Parasitica (1994), 50(1-2),

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See detailHistoire naturelle des anévrysmes de l'aorte abdominale
SakalihasanN, Natzi ULg; Limet, Raymond ULg

in Revue Médicale de Liège (1994), 49(10), 545-52

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See detailHIGH-RESOLUTION SPECTRA OF JUPITER NORTHERN AURORAL ULTRAVIOLET EMISSION WITH THE HUBBLE-SPACE-TELESCOPE
TRAFTON, L. M.; Gérard, Jean-Claude ULg; Munhoven, Guy ULg et al

in Astrophysical Journal (1994), 421(2), 816-827

The first spectroscopic observations of planetary aurora with the HST are reported. These include spectral regions centered on the H-2 Lyman and Werner bands of a region of Jupiter's northern aurora. The ... [more ▼]

The first spectroscopic observations of planetary aurora with the HST are reported. These include spectral regions centered on the H-2 Lyman and Werner bands of a region of Jupiter's northern aurora. The observations were made with the Goddard High Resolution Spectrograph (GHRS) using the Large Science Aperture as part of a campaign to study Jupiter at the time of the Ulysses flyby. The individual rotational-vibrational bands are resolved and the observed emissions are essentially all from H-2. A rotational-vibrational temperature for H-2 of 530 +/- 100 K is derived, a value significantly less than the 850-1100 K reported for Jovian H-3(+) in the near-infrared but consistent with the temperature reported for fundamental-band quadrupole H-2 emission. Comparison with the Faint Object Camera (FOC) images shows that the observed region was not one of the hot spots of the aurora. The results are interpreted in terms of electron impact excitation of H-2 from secondary particles generated by primaries precipitating into Jupiter's atmosphere from the magnetosphere. In the region of the aurora observed, the homopause level is found to be significantly hotter but not necessarily higher than observed at nonauroral latitudes. The equatorial H-2 dayglow spectrum was also detected; its intensity was 3.2 kR or 13% of the strength of the observed auroral emission. [less ▲]

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See detailANOMALOUS PERTURBATIVE TRANSPORT IN TOKAMAKS DUE TO DRIFT-ALVEN-WAVE TURBULENCE
Thoul, Anne ULg; SIMILON, P. L.; SUDAN, R. N.

in Physics of Plasmas (1994), 1(3), 601-608

The method developed in Thoul, Similon, and Sudan [Phys. Plasmas 1, 579 (1994)] is used to calculate the transport due to drift-Alfven-wave turbulence, in which electromagnetic effects such as the ... [more ▼]

The method developed in Thoul, Similon, and Sudan [Phys. Plasmas 1, 579 (1994)] is used to calculate the transport due to drift-Alfven-wave turbulence, in which electromagnetic effects such as the fluttering of the magnetic field lines are important. Explicit expressions are obtained for all coefficients of the anomalous transport matrix relating particle and heat fluxes to density and temperature gradients in the plasma. Although the magnetic terms leave the transport by trapped electrons unaffected, they are important for the transport by circulating electrons. [less ▲]

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